LOCUS       DAVBOD010000001        75387 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 640-05
            SAMEA1012484-rid20186543.denovo.001, whole genome shotgun sequence.
ACCESSION   DAVBOD010000001 DAVBOD010000000
VERSION     DAVBOD010000001.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012484
            Sequence Read Archive: ERR059358
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 75387)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 75387)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979948.1
            Genome Coverage       :: 595x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:03:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,266
            CDSs (total)                      :: 2,219
            Genes (coding)                    :: 2,091
            CDSs (with protein)               :: 2,091
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 71 of 128
            Pseudo Genes (incomplete)         :: 50 of 128
            Pseudo Genes (internal stop)      :: 33 of 128
            Pseudo Genes (multiple problems)  :: 22 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..75387
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012484-rid20186543.denovo.001"
                     /strain="NIG 640-05"
                     /db_xref="taxon:1313"
     gene            complement(141..1010)
                     /locus_tag="VQ862_000001"
     CDS             complement(141..1010)
                     /locus_tag="VQ862_000001"
                     /EC_number="2.7.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000692406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine kinase"
                     /protein_id="HET3114426.1"
                     /translation="MKIIVPATSANIGPGFDSVGVAVTKYLQIEVCEERDEWLIEHQI
                     GKWIPHDERNLLLKIALQIVPDLQPRRLKMTSDVPLARGLGSSSSVIVAGIELANQLG
                     QLNLSDHEKLQLATKIEGHPDNVAPAIYGNLVIASSVEGQVSAIVADFPECDFLAYIP
                     NYELRTRDSRSVLPKKLSYKEAVAASSIANVAVAALLAGDMVTAGQAIEGDLFHERYR
                     QDLVREFAMIKQVTKENGAYATYLSGAGPTVMVLASHDKMPTIKAELEKQPFKGKLHD
                     LRVDTQGVRVEAK"
     gene            complement(1012..2298)
                     /locus_tag="VQ862_000002"
     CDS             complement(1012..2298)
                     /locus_tag="VQ862_000002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine dehydrogenase"
                     /protein_id="HET3114427.1"
                     /translation="MTVKIALLGFGTVASGVPFLLKENGGKINQSAHSDIKVAKVLVK
                     DEDEKNRLLAAGNDFNFVTNVDDILSDQDITIVVELMGRIEPAKTFITRALEAGKHVV
                     TANKDLLAVHGAELLEIAQANKVALYYEAAVAGGIPILRTLANSLASDKITRVLGVVN
                     GTSNFMVTKMVEEGWSYDDALAEAQRLGFAESDPTNDVDGIDAAYKMVILSQFAFGMK
                     IAFDDVAHKGIRNITPEDVAVAQELGYVVKLVGSIEETSSGIAAEVTPTFLPKAHPLA
                     SVNGVMNAVFVESIGIGESMYYGPGAGQKPTATSVVADIVRIVRRLNDGTIGKDFNEY
                     SRDLVLANPEDVKANYYFSILALDSKGQVLKLAEIFNAQDISFKQILQDGKEGDKARV
                     VIITHKINKAQLENVSAELKKVSEFDLLNTFKVLGE"
     gene            complement(2449..3186)
                     /gene="mecA"
                     /locus_tag="VQ862_000003"
     CDS             complement(2449..3186)
                     /gene="mecA"
                     /locus_tag="VQ862_000003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000782680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adaptor protein MecA"
                     /protein_id="HET3114428.1"
                     /translation="MKMKQISDTTLKITMSLEDLMDRGMEIADFLVPQEKTEEFFYAI
                     LDELEMPDSFLDTGMLSFRVTPKPDKVDVFVTKSKIDQNLDFEDLSDLPDMEELAQMS
                     PDEFIKTLEKSIADKTKDDIEAIQSLEQVEAKEEEQEQAEQEAESKKEPYIYYILSFA
                     KLADLVAFAKTVTFEMETSELYKMNERYYLTILVDIENHPSPYPAWLLARMREFADDS
                     DISRSVLQEYGQVLMSHDAVLNLQKIG"
     gene            complement(3386..4420)
                     /locus_tag="VQ862_000004"
     CDS             complement(3386..4420)
                     /locus_tag="VQ862_000004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000461501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HET3114429.1"
                     /translation="MFEHYSVADLFANLYKKRKANILALIALFALIAVPFTIKAVRNK
                     NTVKDTTSYSTYLIYKITPPKESAKTILNHQIGGYSDFYGKLIDGNLNGAYLFNDVEP
                     SELKKIASELDTTETTLKNSTNDYWWKKLTVYYMIDDAGVGVKILTSSKDANDLLEKK
                     IDGLIEKFKHAYANVKIEKLETINSKELNANGETALGLNVKNLILRLVVIGVVCVILV
                     VMGNVLVYLFNPTINRVGDFSQYQIDFVTEITTIANLADVLSYKNTGQELTIVSSNKA
                     ILDKLKQSQEALKGMHFVDLQDVSSLLERDTVLLVEEYGVTRYKKFEQSLQILRNLNR
                     SILGVATFKL"
     gene            complement(4449..5882)
                     /locus_tag="VQ862_000005"
     CDS             complement(4449..5882)
                     /locus_tag="VQ862_000005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen polysaccharide polymerase Wzy family
                     protein"
                     /protein_id="HET3114430.1"
                     /translation="MIDGKRLLFSLTIVSYTLTLVSGIVYLFNNNNVSLLSTLLFLLV
                     SSLIACWNDIKYYLIHFIFYLTIFVFLVSRPTIDYFRDGALDTYHPIAYRFAFIVVMV
                     SILGLTTGGVLARYFIARKKIKVANIGNSLKEVYIKRLRFVSLGVFLLTYPFYFIRLF
                     ERLLYRLQTSYYAYYANFESKLPYFTYILSTFTVYAMCMYLATKPKKLQATAVLVSFI
                     AANTIHLAIGTRNPFILSILFAFVYYFMREQTEKGKWIGFKEKLAIFVGSPILMLAMG
                     VLNYVRDNVQVSHTGFWDILLDFIYKQGTSFGVLARGFLFNSSLPYRDFRNFTFGPVL
                     DYFARGSLGAIFGGKAFEHTTNSVELAIDSNSYAHNLSYLVLNKEYLKGHGIGSSYIM
                     ELYTDYGMIGVFLLSFLLGVLFIAMLQVAYRSRTILFALSLLILNNLFFMPRSSFSES
                     FFNLFTMQFWGIVLVIIFVAKMLTKEN"
     gene            complement(5898..6884)
                     /locus_tag="VQ862_000006"
     CDS             complement(5898..6884)
                     /locus_tag="VQ862_000006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000446977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HET3114431.1"
                     /translation="METALISVIVPVYNVAQYLEKSIASIQKQTYQNLEIILVDDGAT
                     DESGRLCDSIAEQDDRVSVLHKKNEGLSQARNDGMKQAHGDYLIFIDSDDYIHPEMIQ
                     SLYEQLVQEDADVSSCGVMNVYANDESPQSANQDDYFVCDSQTFLKEYLIGEKIPGTI
                     CNKLIKRQIATALSFPKGLIYEDAYYHFDLIKLAKKYVVNTKPYYYYFHRGDSITTKP
                     YAKKDLAYIDIYQKFYNEVVKNYPDLKEVAFFRLAYAHFFILDKMLLDDQYKQFEAYS
                     QIHRFLKGYAFAISRNPIFRKGRRISALALFINISLYRFLLLKNIEKSKKLH"
     gene            complement(6886..7989)
                     /locus_tag="VQ862_000007"
     CDS             complement(6886..7989)
                     /locus_tag="VQ862_000007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000225894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HET3114432.1"
                     /translation="MVAKKKILFFMWSFSLGGGAEKILSTIVSNLDPEKYDIDILEME
                     HFDKGYESVPKHVRILKSLQDYRQTRWLRAFLWRMRIYFPRLTRRLLVKDDYDVEVSF
                     TIMNPPLLFSKRREVKKISWIHGSIEELLKDSSKRESHRSQLDAANTIVGISKKTSNS
                     IKEVYPDYASKLQTIYNGYDFQTILEKSQEKIDIEIAPQSICTIGRIEENKGSDRVVE
                     VIRLLHQEGKNYHLYFIGAGDMEEELKKRVKEYEIEDYVHFLGYQKNPYQYLSQTKVL
                     LSMSKQEGFPGVYVEALSLGLPFISTDVGGAEELSQEGRFGQIIESNQEAAQAITNYM
                     TSASNFNVDEASQFIQQFTITKQIEQVEKLLEE"
     gene            complement(7979..8824)
                     /locus_tag="VQ862_000008"
     CDS             complement(7979..8824)
                     /locus_tag="VQ862_000008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001061982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine transferase LicD"
                     /protein_id="HET3114433.1"
                     /translation="MNNMTDLKAIQARSLEMAEYFVAFCKEHDLLCYLCGGGAIGALR
                     NKGFIPWDDDLDFFMPRKDYEKLAELWPRYADERYFLSKSHKDFVDRNLFITIRDKET
                     TCIKPYQQDLDLPHGLALDVLPLDYYPKNPAERKKQVRWALIYSLFCAQTIPEKHGAL
                     MKWGSRILLGLTPKSLRYRIWKKAEKEMTKYDLADCDGITELCSGPGYMRNKYPITSF
                     EDNLFLPFEGTEMPIPIGYDVYLRTAFGDYMTPPPADKKVPHHDAVIADMDKSYTEYK
                     GEYGG"
     gene            complement(9103..10377)
                     /gene="psr"
                     /locus_tag="VQ862_000009"
     CDS             complement(9103..10377)
                     /gene="psr"
                     /locus_tag="VQ862_000009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyisoprenyl-teichoic acid--peptidoglycan
                     teichoic acid transferase Psr"
                     /protein_id="HET3114434.1"
                     /translation="MSKENPLSHHEQLRYDYLLKNIHYLNEREKNEFAYLQEKLTLAR
                     GNSSSSLEQEREEQVDLPSYANRSRSQSKSQALSFPPKKKRRKLRLKRIFMVIFSLLV
                     CVALAMVFMFLRGYQDASAKKTADARAAQVEVFNGQDTRDGVNILIMGTDGRIGQNSV
                     ETRTDSIMVLNVGGSDKKMKLVSFMRDNLVYIDGYSQVINGRKQTDNKLNVAYELGEQ
                     EGQKGAEMVRQVLKDNFDLDIKYYALVDFQAFATAIDTLFPDGVTIDAQFSTLNGRPL
                     TEATVGDDLYATETESPTQTIKVGKQQMNGSTLLNYARFRDDDEADYGRTKRQQQVLT
                     AILEQIKDPTKLFTGSEALGKVFAMTSTNVPYTFLLTNGLSVLDGAKNGIEKLTIPEL
                     GDWVDAYDVYGGLGLLVDQNKYQTKLAQMGLR"
     gene            complement(10374..11222)
                     /gene="pheA"
                     /locus_tag="VQ862_000010"
     CDS             complement(10374..11222)
                     /gene="pheA"
                     /locus_tag="VQ862_000010"
                     /EC_number="4.2.1.51"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HET3114435.1"
                     /translation="MKIAYLGPKGSFSHHVVQIAFPHEELQAFANITDVIKAYEQGLV
                     DYSVVPVENSIEGSVHETLDYLFHQAHIQAVAEIVQPIHQQLMVVPGHTKIEKIFSHP
                     QALAQGKKFIDEQYPEAQIEVTASTAYAARFISEHPDQPFAAVAPRSSAEEYGLELIA
                     EDIQEMEANFTRFWVLGAEKPSIPLQAQTEKMSLALTLPDNLPGALYKALSTFAWRGI
                     DLTKIESRPLKTALGEYFFIIDVDYTDKDLVHFAQKELEAIGIQYKILGAYPIYPISD
                     HGKERR"
     gene            complement(11219..11695)
                     /locus_tag="VQ862_000011"
     CDS             complement(11219..11695)
                     /locus_tag="VQ862_000011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate kinase"
                     /protein_id="HET3114436.1"
                     /translation="MAKVLLGFMGAGKSTIARGLDPNYLDMDALIEKRLGMSIANFFA
                     EKGEAAFRQVESEVLADLLQTDQVVSTGGGVVISQRNRDLLKTNTDNIYLKADFETLY
                     QRIAADKDNQRPLFLNNSKEELVAIFQERQAWYEEVASRVLDVTKLSPEEIIEELR"
     gene            complement(11688..12971)
                     /gene="aroA"
                     /locus_tag="VQ862_000012"
     CDS             complement(11688..12971)
                     /gene="aroA"
                     /locus_tag="VQ862_000012"
                     /EC_number="2.5.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004236106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="HET3114437.1"
                     /translation="MKLKTNIRHLHGSIRVPGDKSISHRSIIFGSLAEGETKVYDILR
                     GEDVLSTMQVFRDLGVEIEDKDGVITIQGVGMAGLKAPQNALNMGNSGTSIRLISGVL
                     AGADFEVEMFGDDSLSKRPMDRVTLPLKKMGVSISGQTERDLPPLRLKGTKNLRPIHY
                     ELPIASAQVKSALMFAALQAKGESVIIEKECTRNHTEDMLKQFGGHLSVDGKKITVQG
                     PQKLTGQKVVVPGDISSAAFWLVAGLIVPNSRLVLQNVGINETRTGIIDVIRAMGGKL
                     EITEIDPVAKSSTLTVESSDLKGTEIGGALIPRLIDELPIIALLATQAQGVTVIKDAE
                     ELKVKETDRIQVVADALNSMGADITPTADGMIIKGKSALHGARVNTFGDHRIGMMTAI
                     AALLVADGEVELDRAEAINTSYPSFFDDLESLIHG"
     gene            complement(13063..13401)
                     /locus_tag="VQ862_000013"
     CDS             complement(13063..13401)
                     /locus_tag="VQ862_000013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000065990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF/YmcA family competence regulator"
                     /protein_id="HET3114438.1"
                     /translation="MSNIYDSANELSRGLRGLPEYKAVKAAKDAIAADAEASKIFTEY
                     LAFQEEIQKLAHTGQMPDASFQAKMEGFGKQIQGNSLLSEFFTKQQQLAIYLSDIEKI
                     VFEPVSELLK"
     gene            complement(13412..14515)
                     /locus_tag="VQ862_000014"
     CDS             complement(13412..14515)
                     /locus_tag="VQ862_000014"
                     /EC_number="1.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydrogenase"
                     /protein_id="HET3114439.1"
                     /translation="MAKTIYIAGLGLIGASMALGIKRDHPDYEILGYNRSQASRDIAL
                     KEGMIDRATDDFASFAPLADVIILSLPIKQTIAFIKELANLDLREGVIISDAGSTKST
                     IVDAAEQYLAGKSVRFVGAHPMAGSHKTGAASADVNLFENAYYIFTPSSLTSQDTLKE
                     MKDLLSGLHARFIEIDAKEHDRVTSQISHFPHILASSLMEQTAVYAQEHEMARRFAAG
                     GFRDMTRIAESEPGMWTSILLSNSETILDRIEDFKERLEVIGQAISKGDEEQIWNFFN
                     QAREQRQTMEIHKRGGVDSSYDLYVDVPDEEDVILRILELLRGTSLVNIHINEENRED
                     IHGILQISFKNAQDLERAEHLITENTDYTVVIK"
     gene            complement(14525..15691)
                     /gene="aroC"
                     /locus_tag="VQ862_000015"
     CDS             complement(14525..15691)
                     /gene="aroC"
                     /locus_tag="VQ862_000015"
                     /EC_number="4.2.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate synthase"
                     /protein_id="HET3114440.1"
                     /translation="MRYLTAGESHGPRLTAIIEGIPAGLPLTAEDINEDLRRRQGGYG
                     RGGRMKIESDQVVFTSGVRHGKTTGAPITMDVINKDHQKWLDIMSAEDIEDRLKSKRK
                     ITHPRPGHADLVGGIKYRFDDLRNSLERSSARETTMRVAVGAVAKRLLAELDMEIANH
                     VVVFGGKEIDVPENLTVAEIKQRAAQSEVSIVNQEREQEIKDYIDQIKRDGDTIGGVV
                     ETVVGGVPVGLGSYVQWDRKLDARLAQAVVSINAFKGVEFGLGFEAGYRKGSQVMDEI
                     LWSKEDGYTRRTNNLGGFEGGMTNGQPIVVRGVMKPIPTLYKPLMSVDIETHEPYKAT
                     VERSDPTALPAAGMVMEAVVATVLAQEILEKFSSDNLEELKEAVAKHRDYTKNY"
     gene            complement(15701..16768)
                     /locus_tag="VQ862_000016"
     CDS             complement(15701..16768)
                     /locus_tag="VQ862_000016"
                     /EC_number="4.2.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-dehydroquinate synthase"
                     /protein_id="HET3114441.1"
                     /translation="MKIRIDIPHHPYDIQIEKGCMAQAGQWLRELWQPQKVVIVTDNH
                     VASLYAEKVKLSLEDAGFQVAVFDFLEGEERKNLTTVQKVYEFLVKQGLTRSDGIVAL
                     GGGVVGDLAGFVASTYMRGIHFVQIPTSLTAQVDSSIGGKTGVNTPFAKNMVGTFAQP
                     DGVLIDPLVLETLGKRELIEGMGEVIKYGLIEDPELWALLTGLNGSVESILEHAETLI
                     EHSCQVKRKMVVEDELDNGIRLYLNFGHTIGHAIEATAGYGKVMHGEAVAMGMVQISK
                     VAEEKGLMPAGITQSITEMCQKFGLPVDYENWEVDKLYQALTHDKKARGNTLKLVLVP
                     ELGSAIIHPVSLEEMKDYLVK"
     gene            complement(16787..17641)
                     /locus_tag="VQ862_000017"
     CDS             complement(16787..17641)
                     /locus_tag="VQ862_000017"
                     /EC_number="1.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HET3114442.1"
                     /translation="MKLDGYTRLAAVVANPIKHSISPFIHNRAFEATDTNGAYVAWEI
                     EASDLVETVANIRRYQMFGINLSMPYKEQVIPYLDKLSDEARLIGAVNTVVNENGNLI
                     GYNTDGKGFFKCLPSFTISGKKMTLLGAGGAAKSILAQAILDGVSQISVFVRSVSMEK
                     TRPYLDKLQEQTGFKVDLCALEYVSELQARIAESDLLVNATSVGMDGQSSPVPENIVL
                     PETLLVADIIYQPFETPFLKWARSQGNPAVNGLGMLLYQAAEAFQLWTGKEMPTEEIW
                     QSLTEKYQ"
     gene            complement(17631..18308)
                     /locus_tag="VQ862_000018"
     CDS             complement(17631..18308)
                     /locus_tag="VQ862_000018"
                     /EC_number="4.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000780376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I 3-dehydroquinate dehydratase"
                     /protein_id="HET3114443.1"
                     /translation="MKLIVSVMPRSLEEAQALDDTRYLDADIIEWRADYLPKEAILQV
                     APAIFEKFAGRELVFTLRTRSEGGEIDLSPEEYIHLIKEVAQLYQPDYIDFEYYSYKD
                     VFEEMLDFPNLVLSYHNFQETPENMMEILSELTILNPKLVKVAVMAHTEQDVLDLMNY
                     TRGFKTLNPEQEYVTISMGKVGKVSRITADVTGSSWSFASLDEVSAPGQISLASMKKI
                     REILDEA"
     gene            complement(18305..19468)
                     /locus_tag="VQ862_000019"
     CDS             complement(18305..19468)
                     /locus_tag="VQ862_000019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001837533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent rRNA methyltransferase"
                     /protein_id="HET3114444.1"
                     /translation="MNRIRVSKRVEKKLAKGLVLLEASDLENVNLKDQEVEVQGQEGN
                     FLGTAYLSQQNKGLGWFVSKDKVAFNQTFFETLFRKAKEKRNAYYQDDLTTAFRLFNQ
                     EGDGFGGLTVDLYGDYAVFSWYNSYVYQIRQTISEAFRQVFPEVLGAYEKIRFKGLDY
                     ESAHVYGQEAPDFFTVLENGVLYQVFMNDGLMTGIFLDQHEVRGSLVDGLAMGKSLLN
                     MFSYTAAFSVAAAMGGASQTTSVDLAKRSRELSQAHFQANGLSTDEHHFIVMDVFEYF
                     KYAKRKDLTYDVIVLDPPSFARNKKQTFSVAKDYHKLISQSLEILNPGGIIIASTNAA
                     NVSRQKFTEQIDKGFAGRSYQILNKYGLPADFAYNKKDESSNYLKVISMKVSK"
     gene            complement(20155..21789)
                     /locus_tag="VQ862_000020"
     CDS             complement(20155..21789)
                     /locus_tag="VQ862_000020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001237556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3114445.1"
                     /translation="MRLKVIKKLVDINILYSSQDANLANPRKKQAKNTGKKVNVSARV
                     LSSYIFSSLLMLIFFSTIAIHFPFEEMPVYFSFMVAILLVIAFSTSLTAFYNVFYESK
                     DLASYSPYAFKESEIIIAKGLSVLLPALTGIVPILAYFLALYISLAPSLWLGLPLMLL
                     SLTLLFVSVTLVTVVAVHFLAQTRVFRKYQSIFSNVMIGIGVLIPLIFIFFLQSTFGS
                     IVDKVRDIPFLLYPLHIFYKIAVEPFSIEAILGLLAWIGLTLFLLYLTKKKVLPRFYD
                     VILLNSEEKVKKERRSKERISTTKKGFFRMVLRYHLTLLGQGTGVVTVLFTSAFLPYL
                     MMIGLISKIRDSQIVPDIHPPYWLPLFFIALFIAVVNNNITSLPSIALSLERENVDFL
                     KSLPFDFARYVKVKFWIIFAVQSFLPILTLLGLSLYLGLPIISMIYLIVAWILASVIL
                     SCHHYFKDVKNLSTNWSSITDLVNRSNGIVAIVLLFIYSAILMALVIGSIFLVQSLSP
                     ILAISLGVGALILLLALAIFGYHYYLSRILAEIEKR"
     gene            complement(21770..22519)
                     /locus_tag="VQ862_000021"
     CDS             complement(21770..22519)
                     /locus_tag="VQ862_000021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000569185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3114446.1"
                     /translation="MIEFQNVSKLYGDKEALSNLNLQIENGEIMGLIGHNGAGKSTTI
                     KSLVSIISPSSGRILVDGQELSENRLAIKRKIGYVADSPDLFLRLTANEFWELIASSY
                     DLSRSDLEASLARLLNVFDFAENRYQVIETLSHGMRQKVFVIGALLSDPDIWVLDEPL
                     TGLDPQAAFDLKQMMKEHAQKGKTVLFSTHVLEVAEQVCDRIAILKKGHLIYCGKVED
                     LRKDNPDQSLESIYLSLAGRKEEVSDASQGH"
     gene            22698..24152
                     /locus_tag="VQ862_000022"
     CDS             22698..24152
                     /locus_tag="VQ862_000022"
                     /EC_number="3.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-amylase"
                     /protein_id="HET3114447.1"
                     /translation="MQNQTLMQYFEWYLPHDGQHWTRLAEDAPHLAHLGISHVWMPPA
                     FKATNEKDVGYGVYDLFDLGEFNQKGTVRTKYGFKEDYLQAIQALKAQGIQPMADVVL
                     NHKAAADHMEAFQVIEVDPVDRTVELGEPFTINGWTSFTFYGRQDTYNDFHWHWYHFT
                     GTDYDAKRRKSGIYLIQGDNKGWANEELVDNENGNYDYLMYADLDFKHPEVIQNIYDW
                     ADWFMETTGVAGFRLDAVKHIDSFFMRNFIRDMKEKYGDDFYVFGEFWNPDKEANLDY
                     LEKTEEHFDLVDVRLHQNLFEASQAGANYDLRGIFTDSLVELKPDKSVTFVDNHDTQR
                     GQALESTVEEWFKPAAYALILLRQDGLPCVFYGDYYGISGQYAQQDFKEILDRLLAIR
                     KDLAYGEQNDYFDHANCIGWVRSGAENQSPIAVLISNDQENSKSMFVGQEWTNQTFVD
                     LLGNHQGQVTIDEEGYGQFPVSARSVSVWAVNTI"
     gene            complement(24241..26859)
                     /gene="alaS"
                     /locus_tag="VQ862_000023"
     CDS             complement(24241..26859)
                     /gene="alaS"
                     /locus_tag="VQ862_000023"
                     /EC_number="6.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012130635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--tRNA ligase"
                     /protein_id="HET3114448.1"
                     /translation="MKQLSSAQVRQMWLDFWATKGHSVEPSVSLVPVNDPTLLWINSG
                     VATLKKYFDGTIIPENPRITNAQKAIRTNDIENVGKTARHHTMFEMLGNFSIGDYFRD
                     EAITWAYELLTSPEWFDFPAEKLYMTYYPDDKDSYNRWIEVGVDPSHLIPIEDNFWEI
                     GAGPSGPDTEIFFDRGEAFDPENIGLRLLAEDIENDRYIEIWNIVLSQFNADPAVPRS
                     EYKELPHKNIDTGAGLERLVAVIQGAKTNFETDLFMPIIREVEKLSGKVYDQDGDNMS
                     FKVIADHIRSLSFAIGDGALPGNEGRGYVLRRLLRRASMHGQKLGINEPFLYKLVPTV
                     GKIMESYYPEVLEKRDFIEKIVKSEEESFARTLHSGQHFAQGIVADLKEKGQSVIAGS
                     DVFKLYDTYGFPVELTEEIAEEAGMTVDREGFEAAMKEQQERARASAVKGGSMGMQNE
                     TLQNITVESVFNYNASQLSSKLVAIVADNAEVEAVSEGTASLIFAETSFYAEMGGQVA
                     DYGQILDESGKVVATVTNVQKAPNGQALHTVEVLAPLALNQEYTLVIDSNRRHRVMKN
                     HTATHLLHAALHNILGNHATQAGSLNEVEFLRFDFTHFQAVTAEELRAIEQQVNEKIW
                     EALEVKTVETDIDTAKEMGAMALFGEKYGKEVRVVTIGDYSIELCGGTHVGNTSEIGL
                     FKIVKEEGIGSGTRRILAVTGKEAFEAYREQEDALKAVAATLKAPQVKEVPHKVEGLQ
                     EQLRQLQKENAELKEKAAAAAAGDIFKDAKEVNGHRYIASQVSVSDAGALRTFADNWK
                     QKDYSDLLVLVAAIGDKVNVLVASKTKDLHAGNLVKELAPIIDGRGGGKPDMAMAGGS
                     NQAKIQELLDVVAGKL"
     gene            complement(26881..27366)
                     /locus_tag="VQ862_000024"
     CDS             complement(26881..27366)
                     /locus_tag="VQ862_000024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000847073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LURP-one-related family protein"
                     /protein_id="HET3114449.1"
                     /translation="MKTFLVKQKFRLGGERFAIKDDRGEIAYQVEGSFFKIPKTFTIY
                     DAAGEQVSQISKEILTLLPRFEIQLRDGSSFVIRKKLTFWRDKYEFDNLGLRIEGNIW
                     DLNFKLLDDRDQLIAEIKKELFHLTSTYTVTVLEDAYADLVISLCVAIDYVEMLESQS
                     H"
     gene            complement(27641..27880)
                     /locus_tag="VQ862_000025"
     CDS             complement(27641..27880)
                     /locus_tag="VQ862_000025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000784186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3114450.1"
                     /translation="MKMSTFFKNSFWPTFMIVNQTAILFHLKDGLDRQYLTTESIYWV
                     IGTFIFGNILVAVFSNMKIWDKKKNGSKKKYILKK"
     gene            complement(28141..29211)
                     /locus_tag="VQ862_000026"
     CDS             complement(28141..29211)
                     /locus_tag="VQ862_000026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HET3114451.1"
                     /translation="MKKIYSFLAGIAAIILVLWGIATHLDSKINSRDSQKLVIYNWGD
                     YIDPELLTQFTEETGIQVQYETFDSNEAMYTKIKQGGTTYDIAIPSEYMINKMKDEDL
                     LVPLDYSKIKGIENIGPEFLNQSFDPGNKFSIPYFWGTLGIVYNETMVDEAPEHWDDL
                     WKPEYKNSIMLFDGAREVLGLGLNSLGYSLNSKDLQQLEETVDKLYKLTPNIKAIVAD
                     EMKGYMIQNNVAIGVTFSGEASQMLEKNENLRYVVPTEASNLWFDNMVIPKTVKNQNS
                     AYAFINFMLKPENALQNAEYVGYSTPNLPAKELLPEETKEDKAFYPDVETMKHLEVYE
                     KFDHKWTGKYSDLFLQFKMYRK"
     gene            complement(29208..29981)
                     /locus_tag="VQ862_000027"
     CDS             complement(29208..29981)
                     /locus_tag="VQ862_000027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET3114452.1"
                     /translation="MKKFANLYLGLVFLVLYLPIFYLIGYAFNAGDDMNSFTGFSWTH
                     FETMFGDGRLMLILAQTFFLAFLSALIATIIGTFGAIYIYQSRKKYQEAFLSLNNILM
                     VAPDVMIGASFLILFTQLKFSLGFLTVLSSHVAFSIPIVVLMVLPRLKEMNGDMIHAA
                     YDLGASQFQMFKEIMLPYLTPSIIAGYFMAFTYSLDDFAVTFFVTGNGFSTLSVEIYS
                     RARKGISLEINALSALVFLFSIILVVGYYFISREKEEQA"
     gene            complement(29978..30784)
                     /locus_tag="VQ862_000028"
     CDS             complement(29978..30784)
                     /locus_tag="VQ862_000028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET3114453.1"
                     /translation="MKKTSSKLFVVPYMLWIALFVLAPLVLIFGQSFFNIEGQFSLEN
                     YKSYFASQNLTYLKMSFNSVLYAGIVTFVTLLISYPTALFLTRLKHRQLWLMLIILPT
                     WINLLLKAYAFIGIFGQNGSINQFLEFIGIGSQQLLFTDFSFIFVASYIELPFMILPI
                     FNVLDDMDNNLINASYDLGATKWETFRHVIFPLSMNGVRSGVQSVFIPSLSLFMLTRL
                     IGGNRVITLGTAIEQNFLTNDNYGMGSTIGVILILTMFITMWVTKERRER"
     gene            complement(30765..31922)
                     /locus_tag="VQ862_000029"
     CDS             complement(30765..31922)
                     /locus_tag="VQ862_000029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018372333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3114454.1"
                     /translation="MKKPIIEFKNVSKVFEDSNTKVLKDINFELEEGKFYTLLGASGS
                     GKSTILNIIAGLLDATTGDIMLDGVRINDIPTNKRDVHTVFQSYALFPHMNVFENVAF
                     PLRLRKIDKKEIEQRVAEVLKMVQLEGYEKRSIRKLSGGQRQRVAIARAIINQPRVVL
                     LDEPLSALDLKLRTDMQYELRELQQRLGITFVFVTHDQEEALAMSDWIFVMNDGEIVQ
                     SGTPVDIYDEPINHFVATFIGESNILPGTMIEDYLVEFNGKRFEAVDGGMKPNEPVEV
                     VIRPEDLRITLPEEGKLQVKVDTQLFRGVHYEIIAYDELGNEWMIHSTRKAIVGEEIG
                     LDFESEDIHIMRLNETEEEFDARIEEYVEIEEQEAGLINAIEEERDEENKL"
     gene            complement(32082..32987)
                     /gene="murB"
                     /locus_tag="VQ862_000030"
     CDS             complement(32082..32987)
                     /gene="murB"
                     /locus_tag="VQ862_000030"
                     /EC_number="1.3.1.98"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000116193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate dehydrogenase"
                     /protein_id="HET3114455.1"
                     /translation="MSVREKMLEILEGIDIRFKEPLHSYSYTKVGGEADYLVFPRNRF
                     ELARLVKFANQENIPWMVLGNASNIIVRDGGIRGFVILCDKLNNVSVDGYTIEAEAGA
                     NLIETTRIALRHSLTGFEFACGIPGSVGGAVFMNAGAYGGEIAHILQSCKVLTKDGEI
                     ETLSAKDLAFGYRHSAIQESGAVVLSVKFALAPGTHQVIKQEMDRLTHLRELKQPLEY
                     PSCGSVFKRPVGHFAGQLISEAGLKGYRIGGVEVSEKHAGFMINVADGTAKDYEDLIQ
                     SVIEKVKEHSGITLEREVRILGESK"
     gene            complement(33099..33851)
                     /locus_tag="VQ862_000031"
     CDS             complement(33099..33851)
                     /locus_tag="VQ862_000031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000152219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhfC family intramembrane metalloprotease"
                     /protein_id="HET3114456.1"
                     /translation="MTIHIIITMLLLLAFLIGSIWFTKKKYQINLAVLGLGAVAFFVS
                     SQILEKLVHILILHPQKDGSIALLQDHPLIYIIYGLAMAAFFEETARLVFFKWLEKKR
                     SLEKADALAYGLGHGGLELIFLGLISLLNLYIVLSAVQTQNPQVMQLLSENMLKTIQS
                     LSVWQIYLLGFERILALGFQLLLTVWVYQAVRQKKWIYLLAAYGLHAFFDLAPSLFQV
                     GWLTNPVLVEVILALELVLVAYGTKEIFCKKS"
     gene            complement(33861..34592)
                     /gene="budA"
                     /locus_tag="VQ862_000032"
     CDS             complement(33861..34592)
                     /gene="budA"
                     /locus_tag="VQ862_000032"
                     /EC_number="4.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000360290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate decarboxylase"
                     /protein_id="HET3114457.1"
                     /translation="MDKNVQEPVKLFQYNTLGALMAGLYGGTMTVGELLEHGDLGLGT
                     LDSIDGELIVLDGKAYQAKESGDQPEIVEVSPDALIPYAAVVPHQAEVIFRQRFEMTD
                     KELKERIESYYDGENLFRSIKIRGEFSHMHVRMIPKSTPDTKFADIATHQPEYSRDNV
                     AGTIVGFWTPQIFHGVSVAGYHLHFISDDLTFGGHVMDFVIKEGIIEVGAVDQLDQRF
                     PVQDRQYLFAKFNVDEMKKDIEKAE"
     gene            34734..36005
                     /locus_tag="VQ862_000033"
     CDS             34734..36005
                     /locus_tag="VQ862_000033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HET3114458.1"
                     /translation="MKKQSKYKEVVSYLKNGIESGRFPTGSRLPSIRQLSLDFHCSKD
                     TIQRALLELRHEQYLYAKPQSGYYVLEQGQHQDLEIEVTDEHASAYDDFRLCVNETLI
                     GRENYLFNYYDNQEGLEDLRQSIHKLLFDQALYCKANQLVLTSGTQQALFILSQISFP
                     SQAKEILVEQPTYHRMNRLLIAQGLDYQTIERGIDGIDLEELEGHFKTGKIKFFYTIP
                     RFHYPLGHSYSEQDKRAILDLAAKYSVYIVEDDYLGDLDSKKGQTFHYLDTEERVIYI
                     KSFSTSLFPALRITALILPNTIKEAFVAYKNILDYDSNLIMQKALSLYIDSQLFEKNR
                     LARLTNHESYQKQIEERITKTPCPLPHYPLHDGLLLDLRQYPKIASLKHSQLGLDFFE
                     EAYLSTCPYQFAKVSLDNLENVLNYLKAELE"
     gene            complement(36025..36851)
                     /locus_tag="VQ862_000034"
                     /pseudo
     CDS             complement(36025..36851)
                     /locus_tag="VQ862_000034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000837371.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
     gene            complement(37008..37661)
                     /gene="phoU"
                     /locus_tag="VQ862_000035"
     CDS             complement(37008..37661)
                     /gene="phoU"
                     /locus_tag="VQ862_000035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000946475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HET3114459.1"
                     /translation="MLRSQFEEDLEKLHNQFYAMGQEVLSQINRTVRAFVTHDRDLAK
                     EVIEDDAEVNEYEVKLEKKSFEMIALQQPVSQDLRTVLTVLKAVSDVERMGDHAVAIA
                     QATIRMKGEERIPAVEEEIKKMGREVKSVVEAALDLYLNGSVDDAYRVASMDEQINHY
                     FETIRDLATEEIKKNPEAIVTGRDYFQVISYLERIGDYAKNICEWVVYFETGKIVEL"
     gene            complement(37673..38431)
                     /gene="pstB"
                     /locus_tag="VQ862_000036"
     CDS             complement(37673..38431)
                     /gene="pstB"
                     /locus_tag="VQ862_000036"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014713134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HET3114460.1"
                     /translation="MTDAILQVSDLSVYYNKKKALNSVSLSFQPKEITALIGPSGSGK
                     STLLKSLNRMGDLNPEVTTTGSVVYNGHNIYSPRTDTVELRKEIGMVFQQPNPFPMTI
                     YENVVYGLRINGIKDKQVLDEAVEKALQGASIWDEVKDRLYDSAIGLSGGQQQRVCVA
                     RVLATSPKIILLDEPTSALDPISAGKIEETLYGLKDKYTMLLVTRSMQQASRISDKTG
                     FFLDGDLIEFNDTKQMFLDPQHKETEDYITGKFG"
     gene            complement(38444..39247)
                     /gene="pstB"
                     /locus_tag="VQ862_000037"
     CDS             complement(38444..39247)
                     /gene="pstB"
                     /locus_tag="VQ862_000037"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000852852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HET3114461.1"
                     /translation="MSTYNWDEKHILTFPEEKVALSTKDVHVYYGKNESIKGIDMQFE
                     RNKITALIGPSGSGKSTYLRSLNRMNDTIDIAKVTGQILYRGIDVNRPEINVYEMRKH
                     IGMVFQRPNPFAKSIYRNITFAHERAGVKDKQVLDEIVETSLRQAALWDQVKDDLHKS
                     ALTLSGGQQQRLCIARAISVKPDILLMDEPASALDPIATMQLEETMFELKKNFTIIIV
                     THNMQQAARASDYTGFFYLGDLIEYDKTATIFQNAKLQSTNDYVSGHFG"
     gene            complement(39258..40142)
                     /gene="pstA"
                     /locus_tag="VQ862_000038"
     CDS             complement(39258..40142)
                     /gene="pstA"
                     /locus_tag="VQ862_000038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009443446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HET3114462.1"
                     /translation="MRAKKLDKLATAVLYTIASIIVTILASLILYILVRGLPHISWSF
                     LTGRSSAFQAGGGIGIQLYNSFFLLVITLIISVPLSMGAGIYLAEYAKKGPVTNFVRT
                     CIEILSSLPSVVVGLFGYLIFVVQFEYGFSIISGALALTVFNLPQMTRNVEDSLKHVH
                     HTQREAGLALGISRWETVVHVVIPEALPGIVTGVVLASGRIFGEAAALIYTAGQSAPA
                     LDWSNWNILSVTSPISIFRQAETLAVHIWKVNSEGTIPDGTIVSAGSAAVLLIFILIF
                     NFGARKFGSYLHKKLTAA"
     gene            complement(40132..41049)
                     /gene="pstC"
                     /locus_tag="VQ862_000039"
     CDS             complement(40132..41049)
                     /gene="pstC"
                     /locus_tag="VQ862_000039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018378778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HET3114463.1"
                     /translation="MNQEELAKKMLLPSKNSRLEKLGKGLTFACLSLIVILVAMILVF
                     VAQKGLSTFFVNGVNIFDFLLGGTWNPSSKEFGALPMILGSFIVTILSALIATPFAIG
                     AAVFMTEVSPKGAKILQPAIELLVGIPSVVYGFIGLQVVVPFVRSVFGGTGFGILSGI
                     SVLFVMILPTVTFMTTDSLRAVPRYYREASFAMGATRWQTIWRVILKAARSGIFTAVV
                     FGMARAFGEALAIQMVVGNSAVIPTSLTTPAATLTSILTMGIGNTVMGTVNNNVLWSL
                     ALVLLLMSLVFNSVIKLITKERGKKNYAR"
     gene            complement(41049..41927)
                     /gene="pstS"
                     /locus_tag="VQ862_000040"
     CDS             complement(41049..41927)
                     /gene="pstS"
                     /locus_tag="VQ862_000040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS"
                     /protein_id="HET3114464.1"
                     /translation="MKKRKKLALSLIAFWLTACLVGCASWIDRGESITAVGSTALQPL
                     VEVAADEFGTIHVGKTVNVQGGGSGTGLSQVQSGAVDIGNSDVFAEEKDGIDASALVD
                     HKVAVAGLALIVNKEVDVDNLTTEQLRQIFIGEVTNWKEVGGKDLPISVINRAAGSGS
                     RATFDTVIMEGQSAMQSQEQDSNGAVKSIVSKSPGAISYLSLTYIDDSVKSMKLNGYD
                     LSPENISSNNWPLWSYEHMYTLGQPNELAAEFLNFVLSDETQEGIVKGLKYIPIKEMK
                     VEKDAAGTVTVLEGRQ"
     gene            complement(42501..43805)
                     /locus_tag="VQ862_000041"
     CDS             complement(42501..43805)
                     /locus_tag="VQ862_000041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001160253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RsmF rRNA methyltransferase first C-terminal
                     domain-containing protein"
                     /protein_id="HET3114465.1"
                     /translation="MKFPEGFVEKYKEILGDEARDFLASFEEEAVSAFRVNPLKEEQL
                     SFSDAITQTPWGHYGKVSGKSPEHATGLVYSQEPAAQMVAQVAQPSPGMKVLDLAAAP
                     GGKSTQLAAYLAGEGLLVSNEISSKRAKILVENMERFGATNVVVTNESADRLVKVFKG
                     YFDLIVLDAPCSGEGMFRKQPDAMDYWSLDYPSQCASLQREILEDAVTMLAEGGRLVY
                     STCTWAPEENEEIVNWLLEEYDFDLLPVEHINGMVAGIDLPETARMYPHQFKGEGQFV
                     AHLQFKGNNPAPKFKASKSNLSREQVALWQEFAQNHLKVNLPGILQIFGDQLYLLPEL
                     LPDLGKLKIARNGLHLGTFKKKRFEPSFALGLALKPSQVEQSVEIGQEEFVKYAAGET
                     VQLAESLPNGWYQVLVKGNGLGFAKVTGNVLKNYFPKGLRFK"
     gene            complement(43806..44579)
                     /locus_tag="VQ862_000042"
     CDS             complement(43806..44579)
                     /locus_tag="VQ862_000042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inositol monophosphatase family protein"
                     /protein_id="HET3114466.1"
                     /translation="MESKFEFAKELVKKAGQYILDHMQEDLRVETKSSPTDLVTRLDK
                     EVQELLVGEILSRYPEDKICAEEGCLRASVQEGKVWVIDPIDGTNNFVAQQEDFAVMM
                     AYFENGQGQFGLIYDVVKGDCYHGGGEFPVCLNDRPLASFKTKPLGDFLIAGNSGMLE
                     TNEWGLADLSRAVLGVRVYGSAAISFAKILSGRLLTYLTYLQPWDYAAASILGESLGY
                     RVVTLFGEAPDFQTRQPVMMVPLEMQEEIQSYIYERKRT"
     gene            complement(44569..44847)
                     /locus_tag="VQ862_000043"
     CDS             complement(44569..44847)
                     /locus_tag="VQ862_000043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0223 family protein"
                     /protein_id="HET3114467.1"
                     /translation="MNKQYSYPLDLSWSTEELASVLSFFNDVEAAYEGKVEAKKLLDS
                     YKGFKAVVPSKSEEKRLGREFETVSGYSLYRAVQAAKEKGEGKISLGK"
     gene            complement(44847..45248)
                     /locus_tag="VQ862_000044"
     CDS             complement(44847..45248)
                     /locus_tag="VQ862_000044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007556665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HET3114468.1"
                     /translation="MITLFLSPSCTSCRKAKAWLEKHKVPFVEHNIMTSPLTRKELQQ
                     ILSLTENGTDDIISTRSKIFQKLNIDVESISVSELLHLIEQYPSLLRRPIIIDAKRMQ
                     IGFNEDEIRAFLPRSYRKQELKEARMRAGIS"
     gene            complement(45457..46074)
                     /locus_tag="VQ862_000045"
     CDS             complement(45457..46074)
                     /locus_tag="VQ862_000045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01906 family membrane protein"
                     /protein_id="HET3114469.1"
                     /translation="MKTKLIFWGSMLFLLSLSILLTIYLAWIFYPMEIQWLNLTNRVY
                     LKPETIQYNFHILMNYLTNPFSQVLQMPDFRSSAAGLHHFAVVKNLFHLVQLVALVTL
                     PSFYVFVNRIVKKDFLSLYRKSLLTLVVLPVMIGLGGVLIGFDQFFTLFHQILFVGDD
                     TWLFDPAKDPVIMILPETFFLHAFLLFFALYESFFGYLCLKSRRK"
     gene            complement(46064..46837)
                     /locus_tag="VQ862_000046"
     CDS             complement(46064..46837)
                     /locus_tag="VQ862_000046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01457 family HAD-type hydrolase"
                     /protein_id="HET3114470.1"
                     /translation="MKYKGYLIDLDGTIYKGKDRIPAGETFVHELQKRDIPYLFVTNN
                     TTRTPESVKEMLAQNFNIDTPLSTVYTATLATIDYMNDLGLEKTVYVVGEAGLKEAIK
                     AAGYVEDKENPAYVVVGLDWQVDYEKFATATLAIQKGAHFIGTNPDLNIPTERGLLPG
                     AGSLITLLEVATRVKPVYIGKPNAIIMDKAVEHLGLEREELIMVGDNYLTDIRAGIDN
                     GIPTLLVTTGFTKAEEVAGLPIAPTHVVSSLAEWDFDEN"
     gene            complement(46848..47585)
                     /locus_tag="VQ862_000047"
     CDS             complement(46848..47585)
                     /locus_tag="VQ862_000047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000524807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-[acyl-carrier-protein] thioesterase"
                     /protein_id="HET3114471.1"
                     /translation="MGLTYQMKMKIPFDMADMNGHIKLPDVILLSLQVSGMQSIELGV
                     SDKAILEDYNLVWIIAEYDIEVVRLPRFAEEITIETEALSYNRLFCYRRFTIYNEAGQ
                     ELIHMMATFVLMDRDSRKVHAVEPEIVAPYQSDFDKKLIRGPKYESLEEPISKDYHVR
                     FYDLDMNGHVNNSKYLDWIFEVMGADFLTHYIPKKINLKYVKEVRPGGVITSAVERTG
                     LESKHEITSDGVINAQAIITWKEIKKA"
     gene            complement(47590..48720)
                     /locus_tag="VQ862_000048"
     CDS             complement(47590..48720)
                     /locus_tag="VQ862_000048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxygen-independent coproporphyrinogen III
                     oxidase"
                     /protein_id="HET3114472.1"
                     /translation="MQKKPTSAYVHIPFCTQICYYCDFSKVFIKNQPVDSYLEHLLEE
                     FRSYDIEKLSTLYIGGGTPTALSAPQLEVLLNGLTKNLNLSVLEELTIEANPGDLDAD
                     KIAVLKNSAVNRVSLGVQTFDDKMLKKIGRSHLEKDIYENIDRLKLAGFDNISIDLIY
                     ALPGQTMEQVKENVAKAIGLDIPHMSLYSLILENHTVFMNRMRRGKLPLPKEELEAEM
                     FEYIIAELERAGFEHYEISNFSKPGFESRHNLMYWDNAEYYGIGAGASGYVNGVRYKN
                     HGPIRHYLSAVEEGNACITEDHLSQKEQMEEEMFLGLRKKSGVSMARFEEKFGQSFAG
                     LYGEIVRDLVQQGLMQIEGDHVRMTKRGLFLGDTVAERFILE"
     gene            complement(48804..49193)
                     /locus_tag="VQ862_000049"
     CDS             complement(48804..49193)
                     /locus_tag="VQ862_000049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HET3114473.1"
                     /translation="MGKLSSILLGTVSGAALALFLTSDKGKQVCSQAQDFLDDLREDP
                     EYAKEQVCEKLTEVKEQATDFVLKTKEQVESGEITVDSILAQAKSYAFQATEASKNQL
                     NNLKEQWQEKAEALDDSEEIVIDITEE"
     gene            complement(49209..49592)
                     /locus_tag="VQ862_000050"
     CDS             complement(49209..49592)
                     /locus_tag="VQ862_000050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF948 domain-containing protein"
                     /protein_id="HET3114474.1"
                     /translation="MLEVAYILVALALIVFLVYLIITVQKLGRVIDETEKTIKTLTSD
                     VDVTLHHTNELLAKVNVLADDINVKVATIDPLFSAVADLSLSVSDLNDHARVLSKKAS
                     SAGSKTLKTGASLSALRLASKFFKK"
     gene            complement(49593..50381)
                     /locus_tag="VQ862_000051"
     CDS             complement(49593..50381)
                     /locus_tag="VQ862_000051"
                     /EC_number="2.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolipoprotein diacylglyceryl transferase"
                     /protein_id="HET3114475.1"
                     /translation="MLDPIAIQLGPLAIRWYALCIVTGLILAVYLTMKEAPRKKIIPD
                     DILDFILVAFPLAILGARLYYVIFRFDYYSQNLGEIFAIWNGGLAIYGGLITGALVLY
                     IFADRKLINTWDFLDIAAPSVMIAQSLGRWGNFFNQEAYGATVDNLDYLPGFIRDQMY
                     IEGSYRQPTFLYESLWNLLGFALILIFRRKWKSLRRGHITAFYLIWYGFGRMVIEGMR
                     TDSLMFFGLRVSQWLSVVLIGLGIMIVIYQNRKKAPYYITEEEN"
     gene            complement(50374..51309)
                     /locus_tag="VQ862_000052"
     CDS             complement(50374..51309)
                     /locus_tag="VQ862_000052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HPr kinase/phosphorylase"
                     /protein_id="HET3114476.1"
                     /translation="MSVLVKEVIEKLRLDIVYGEPELLEKEINIADITRPGLEMTGYF
                     DYYTPERIQLLGMKEWSYLISMPSNSRYEVLKKMFLPETPAVIVARGLVVPEEMLKAA
                     RECKIAILTSRAATSRLSGELSSYLDSRLAERTSVHGVLMDIYGMGVLIQGDSGIGKS
                     ETGLELVKRGHRLVADDRVDIFAKDEITLWGEPAEILKHLIEIRGVGIIDVMSLYGAS
                     AVKDSSQVQLAVYLENYDTHKTFDRLGNNAEELEVSGVAIPRIRIPVKTGRNISVVIE
                     AAAMNYRAKEMGFDATRLFDERLTSLIARNEVQNA"
     gene            complement(51439..51615)
                     /locus_tag="VQ862_000053"
     CDS             complement(51439..51615)
                     /locus_tag="VQ862_000053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000048061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S21"
                     /protein_id="HET3114477.1"
                     /translation="MSKTVVRKNESLDDALRRFKRAVTKAGTLQETRKREFYEKPSVK
                     RKRKSEVARKRKKF"
     gene            complement(51755..52462)
                     /locus_tag="VQ862_000054"
     CDS             complement(51755..52462)
                     /locus_tag="VQ862_000054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosamine-6-phosphate deaminase"
                     /protein_id="HET3114478.1"
                     /translation="MKVIKVENQVQGGKVAFEILKEKLANGAQTLGLATGSSPLEFYK
                     EIVESDLDFSNLTSVNLDEYVGLDGDNPQSYRYFMQENLFNQKPFKESFLPRGVKDNA
                     EAEVERYNQILADHPVDLQILGIGRNGHIGFNEPGTPFDSQTHLVELDQSTIEANARF
                     FAKIEDVPTQAISMGIKNILDAKSIILFAYGESKAEAIAGTVSGPVTENLPASSLQNH
                     PDVTIIADAEALSLLEK"
     gene            52613..53641
                     /gene="queA"
                     /locus_tag="VQ862_000055"
     CDS             52613..53641
                     /gene="queA"
                     /locus_tag="VQ862_000055"
                     /EC_number="2.4.99.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA preQ1(34) S-adenosylmethionine
                     ribosyltransferase-isomerase QueA"
                     /protein_id="HET3114479.1"
                     /translation="MNTADFDFHLPEELIAQTPLEKRDASKLLIVNRETGEMQDKHFH
                     SIIDMLEPGDALVMNDTRVLPARLYGQKMETGGHVELLLLKNTSGDEWEVLAKPAKRL
                     KVGTRISFGDGRLSAVVTEELTHGGRIVRFEYQGIFLEVLESLGEMPLPPYIHEKLDD
                     RERYQTVYAKESGSAAAPTAGLHFTKELLAEIQAKGVHLVYLTLHVGLGTFRPVSVDN
                     LDEHEMHSEFYQLSEEAAATLRSVKENGGRVIAVGTTSIRTLETIGSKFDGQIQADSG
                     WTNIFIKPGYEWKVVDAFSTNFHLPKSTLVMLVSAFAGRELVLDAYHHAIQEHYRFFS
                     FGDAMFIY"
     gene            complement(54302..54691)
                     /locus_tag="VQ862_000056"
     CDS             complement(54302..54691)
                     /locus_tag="VQ862_000056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000240828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
                     /protein_id="HET3114480.1"
                     /translation="MVKRRIRRGTREPEKVVVPEQSSIPSYPVSVTSNQGTDVAVEPA
                     KAVAPTTDWKQENGMWYFYNTDGSMATGWVQVNGSWYYLNSNGSMKVNQWFQVGGKWY
                     YVNASGELAVNTSIDGYRVNDNGEWVR"
     gene            complement(54745..55436)
                     /locus_tag="VQ862_000057"
                     /pseudo
     CDS             complement(54745..55436)
                     /locus_tag="VQ862_000057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846497.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
     gene            complement(56151..56702)
                     /locus_tag="VQ862_000058"
     CDS             complement(56151..56702)
                     /locus_tag="VQ862_000058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET3114481.1"
                     /translation="MKSIGTQILQTERLILRRFVESDAEAMFQNWASSAENLTYVTWD
                     PHPDVEITRNSICNWVASYTNLNYYKWAICLKENPEQVIGDISIVKIDEADLSCEIGY
                     VLGKAYWGNGMMTETLKAILDFCFTQAGFQKVRARYASLNPASGRVMEKAGMSYLQTI
                     VNGVERKGYLADLIYYGISREEC"
     gene            complement(57052..57876)
                     /gene="nadE"
                     /locus_tag="VQ862_000059"
     CDS             complement(57052..57876)
                     /gene="nadE"
                     /locus_tag="VQ862_000059"
                     /EC_number="6.3.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000058066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ammonia-dependent NAD(+) synthetase"
                     /protein_id="HET3114482.1"
                     /translation="MSLQETIIQELGVKPVIDAQEEIRRSIDFLKRYLKKHPFLKTFV
                     LGISGGQDSTLAGRLAQLAMEELRAETGDDSYKFIAVRLPYGVQADEADAQKALAFIQ
                     PDVSLVVNIKESADAMTAAVEATGSPVSDFNKGNIKARCRMIAQYALAGSHSGAVIGT
                     DHAAENITGFFTKFGDGGADILPLYRLNKRQGKQLLQKLGAEPALYEKIPTADLEEDK
                     PGLADEVALGVTYAEIDDYLEGKTISPEAQATIENWWHKGQHKRHLPITVFDDFWE"
     gene            complement(57873..59333)
                     /locus_tag="VQ862_000060"
     CDS             complement(57873..59333)
                     /locus_tag="VQ862_000060"
                     /EC_number="6.3.4.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate phosphoribosyltransferase"
                     /protein_id="HET3114483.1"
                     /translation="MYPDDSLTLHTDLYQINMMQVYFDQGIHNKKAVFEVYFRQQPFK
                     NGYAVFAGLERIVNYLEDLRFSDSDIAYLESLGYHGAFLDYLRNFKLELTVRSAQEGD
                     LVFANEPIVQVEGPLAQCQLVETALLNIVNYQTLVATKAARIRSVIEDEPLMEFGTRR
                     AQEMDAAIWGTRAAVIGGANGTSNVRAGKLFDIPVLGTHAHALVQVYGNDYEAFKAYA
                     ATHKNCVFLVDTYDTLRIGVPAAIQVARELGDQINFMGVRIDSGDIAYISKKVRQQLD
                     EAGFTEAKIYASNDLDENTILNLKMQKAKIDVWGVGTKLITAYDQPALGAVYKIVAIE
                     DETGQMRNTIKLSNNAEKVSTPGKKQVWRITSREKGKSEGDYITYDGVDISDMTEIKM
                     FHPTYTYIKKTVRNFDAVPLLVDIFKEGILVYNLPSLTDIQDYARKEFDKLWDEYKRV
                     LNPQHYPVDLARDVWQDKMDLIDKMRKEALGEGEEE"
     gene            complement(59449..59937)
                     /locus_tag="VQ862_000061"
     CDS             complement(59449..59937)
                     /locus_tag="VQ862_000061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000797183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3114484.1"
                     /translation="MKNRFYYYQLLDEREEQLFNKAGSESFYICIALSLLSYIISVLA
                     PSLFNSNMLLIVIIIGTFYFFNRARYLGVTYYSRFHFTILGCFFLTLAITALLMLQNY
                     QFNIEIYQHNPLNFKYLSAWVITYIIYLPWIFIGNLGLKSYGEWAQKKFEQDMDELES
                     GE"
     gene            complement(59927..60136)
                     /locus_tag="VQ862_000062"
     CDS             complement(59927..60136)
                     /locus_tag="VQ862_000062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013670190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET3114485.1"
                     /translation="MAKNLKLKLARVERDLTQGQLAEAVGVTRQTIGLIEAGKYNPSL
                     SLCQSICRCLGKTLDQLFWEEEDEK"
     gene            complement(60522..61002)
                     /locus_tag="VQ862_000063"
                     /pseudo
     CDS             complement(60522..61002)
                     /locus_tag="VQ862_000063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863700.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(61018..61140)
                     /locus_tag="VQ862_000064"
     CDS             complement(61018..61140)
                     /locus_tag="VQ862_000064"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3114486.1"
                     /translation="MSGNIQNSELFKFFNENSIKVVDFETKKETLKDIYLNRSK"
     gene            complement(61162..61896)
                     /locus_tag="VQ862_000065"
     CDS             complement(61162..61896)
                     /locus_tag="VQ862_000065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001220485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3114487.1"
                     /translation="MRIKEKTNNINGGIKNVSKHYGHSIILKDINFALNKGEIVGLAG
                     RNGVGKSTLMKILVQNNQPTSGNIISSDNVGYLIEEPKLFLSKTGLENLKYLSNLYGV
                     DYNQERFRCLIQELDLTQSINKKVKTYSLGTKQKLALLLTLVTEPDILILDEPTNGLD
                     IESSQIVLAVLKKLALHENVGILISSHKLEDIEEICERVLFLENGLLTFQKVGKDSHN
                     FLFEIAFSSATDRDIFITKQEFWDIV"
     gene            complement(62231..62701)
                     /locus_tag="VQ862_000066"
     CDS             complement(62231..62701)
                     /locus_tag="VQ862_000066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase C-terminal
                     domain-containing protein"
                     /protein_id="HET3114488.1"
                     /translation="MDAYLESPEKFEAIKQDLVDEMWKVAQRELATGFYYGIPSENEQ
                     LFGARRKIPEYKFVAEVISYDDATQTATIRQRNVINEGDQVEFYGPGFRHFETYIEDL
                     HDAKGNKIDRAPNPMELLTIKVPQPVQAGDMVRALKEGLINLYKEDGTSVTVRA"
     gene            complement(62722..62961)
                     /locus_tag="VQ862_000067"
     CDS             complement(62722..62961)
                     /locus_tag="VQ862_000067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HET3114489.1"
                     /translation="MRDANRGGCSQSCRWKYDLYDMPFGKERKSLQGEIPEEFSMSAV
                     DMSMIDHIPDMIENGVDNLKIEGRMEWSLFTTYQQ"
     gene            complement(63210..63521)
                     /locus_tag="VQ862_000068"
     CDS             complement(63210..63521)
                     /locus_tag="VQ862_000068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3114490.1"
                     /translation="MIEAQGFLVDKQTRCIHYHSKLDIIALQCYDCKKYYACYRCHDS
                     LENHPFEPYPLSLIQDKPILCGVCLKLLTYKQYKESLSCPFCFSRFNPGCQNHKERYF
                     K"
     gene            complement(63536..64822)
                     /locus_tag="VQ862_000069"
     CDS             complement(63536..64822)
                     /locus_tag="VQ862_000069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HET3114491.1"
                     /translation="MTKTLKRPEVLSPAGTLEKLKVAVQYGADAVFIGGQAYGLRSRA
                     GNFTFEQMEEGVQFAAKYGAKVYVAANMVMHEGNEAGAGEWFRKLRDIGIAAVIVSDP
                     ALIMIAATEAPGLEIHLSTQASATNYETLEFWKELGLTRVVLAREVSMEELAEIRKRT
                     DVEIEAFVHGAMCISYSGRCTLSNHMSMRDANRGGCSQSCRWKYDLYDMPFGKERKSL
                     QGEIPEEFSMSAVDMSMIDHIPDMIENGVDSLKIEGRMKSIHYVSTVTNCYKAAVDAY
                     LESPEKFEAIKQDLVDEMWKVAQRELATGFYYGIPSENEQLFGARRKIPEYKFVAEVV
                     SYDDATQTATIRQRNVINEGDQVEFYGPGFRHFETYIEDLHDAKGNKIDRAPNPMELL
                     TIKVPQPVQAGDMVRALKEGLINFYKEDGTSVTVRA"
     gene            65445..65627
                     /locus_tag="VQ862_000070"
     CDS             65445..65627
                     /locus_tag="VQ862_000070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001262531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ApaLI family restriction endonuclease"
                     /protein_id="HET3114492.1"
                     /translation="MANDNKSHYLIYRVLGISFEEGENIDLYQNKGRFLYKYAGSFLE
                     EAAVLSFNEKFGTENP"
     gene            65637..65987
                     /locus_tag="VQ862_000071"
     CDS             65637..65987
                     /locus_tag="VQ862_000071"
                     /inference="COORDINATES: protein motif:HMM:NF021048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ApaLI family restriction endonuclease"
                     /protein_id="HET3114493.1"
                     /translation="MPNSESTKPKTFEIDCLVGEKHAYEIKWWDATTDGDHITKEHTR
                     IKVIHNKGYIPIRLMFYYPNRTQAIKIQQTLETLYNGIGGKYYGDSAWEDLRAVTGID
                     LLSILTDIANKKQG"
     gene            65995..67185
                     /locus_tag="VQ862_000072"
     CDS             65995..67185
                     /locus_tag="VQ862_000072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific DNA-methyltransferase"
                     /protein_id="HET3114494.1"
                     /translation="MTVLKGDNLEILKTIESSSIDLIYMDPPFFTQKTQKLSNNKNIM
                     YSFEDTWTSIEDYKEFLSVRLEECKRVLKNSGSIFVHCDKIANHHIRLILDNIFGADM
                     FQSEIIWNYKRWSNSKKGLLNNHQNIYFYSKSKDFKFNTIFTEYSSTTNIDQILVERK
                     RDGNSKTIYKVDNNGNYILAKEKNGVPLSDVWNIPFLNPKAKERVGYPTQKPILLLEQ
                     IIKIATDKNDIVLDPFCGSGTTLVASKILNRNYMGIDLSEEAINITQQRLENVIKTSS
                     DLLNKGIEAYRTKTEEEENILKLLQAKIVQRNKGIDGFLPKHFQKKPIPIKIQKNNEC
                     LNESISLLQNAINSKKLDFGVVIKTHSDNLLFDFDTIPENIIVVDHFELTIEKWLSKS
                     QQLL"
     gene            complement(67700..68692)
                     /locus_tag="VQ862_000073"
     CDS             complement(67700..68692)
                     /locus_tag="VQ862_000073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000122906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET3114495.1"
                     /translation="MSYYDFVKDYMKVDECKNNEKYSSAGHTFCWKKENSTYAEGLYW
                     FYEGGSFIIDIHDFYIKEEVVQNSTYSMSDYVSIYSSYIVSANGEKFNPYQTITANSL
                     CTFDFDNIKDDFVFLLHENCCYLAVSIGFKKELIEKHLASININPESFYSTLLQSNQI
                     ILTKALERVAMEILNCKMDAPAADFFFKAKANEWISIVIDTYLNRKKYKIEIDDDKAL
                     EDVARFLDDHFATNVNQGTLEKISKMSGTKLKNLFKEKYCQSITEYTQRKRMNVAETL
                     LLNTELPIKEIAESVGYSSASKFSIYYKRYKGKLPSEVRNLACKHHNFKCDYCD"
     gene            68852..70606
                     /locus_tag="VQ862_000074"
     CDS             68852..70606
                     /locus_tag="VQ862_000074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3114496.1"
                     /translation="MKIYKKLFAYVQDKKYLGVLAIIFSAISAALTVYGYYLIYKFLD
                     KLIINSNLSGAESIALKSVITLTSGAIFYFVSGMFSHILGFRLETNLRKRGIDGLEKA
                     SFRFFDLNPSGQIRKIIDDNAAQTHQVVAHMIPDSSQAIITPVLVLALGFIVSIRVGI
                     ILLALTIIGGLILGAMMGEQEFMKIYQESLSKLSAETVEYVRGMQVVKIFKANVESFK
                     SFYKAIKDYSKYAYDYSLSCKRPYVLYQWLFFGLIAILIIPIVYFMTSLASAKVILLE
                     LIMILFLSGVLFVSFMRMMWYSMYISQGNYAVDTLEALYEDMQKDKLVHGNVNNFKNY
                     NIEFENVSFAYNDKAVIENLSFNLEEGKSYALVGSSGSGKSTVAKLISGFYNVNKGSI
                     KIGGIAISEYSDEALIKAISFVFQDSKLFKKSIYDNVALANKDATKDDVMRALKLAGC
                     DLILDKFPERENTIIGSKGVYLSGGEKQRIAIARAILKDSKIIIMDEASASIDPDNEF
                     ELQKAFKNLMKDKTVIMIAHRLSTIKDLDEIIVMDSGKIIERGSDKELMSKDTRYKSL
                     QEMFNSANEWRVSNERVL"
     gene            70590..72311
                     /locus_tag="VQ862_000075"
     CDS             70590..72311
                     /locus_tag="VQ862_000075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019214631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3114497.1"
                     /translation="MKEFYKKRFALTDGGARNLSKATLASFFVYCINMLPAILLMIFA
                     QEVLENMGKSNGFYIVFSVLTLIAMYILLSIEYDKLYNTTYQESADLRIRTAENLSKL
                     PLSYFSKHDISDISQTIMADIEGIEHAMSHSIPKVGGMVLFFPLISVMMLAGNVKMGL
                     AVIIPSILSFIFIPLSKKYQVNGQNRYYDVLRKNSESFQENIEMQMEIKAYNLSKDIK
                     DDLYKKMEDSERVHLKAEVTTILTLSISSIFSFISLAVVIFVGVNLIINKEINSLYLI
                     GYLLAAMKIKDSLDASKEGLMEIFYLSPKIERLKEIQNQDLQEGDDYSLKKFDIDLKD
                     VEFAYNKDAKVLNGVSFKAKQGEVTALVGASGCGKTTILKLISRLYDYDKGQILINGK
                     DIKEISTESLFDKVSIVFQDVVLFNQSVMENIRIGKQDASDEEVKRAAKLANCTDFIE
                     KMDKGFDTVIGENGAELSGGERQRLSIARAFLKDAPILILDEITASLDVNNEKKIQES
                     LNNLVKDKTVVIISHRMKSIENADKIVVLQNGRVESEGKHEELLQKSKIYKNLIEKTK
                     MAEEFIY"
     gene            72322..72906
                     /locus_tag="VQ862_000076"
     CDS             72322..72906
                     /locus_tag="VQ862_000076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000368966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MptD family putative ECF transporter S
                     component"
                     /protein_id="HET3114498.1"
                     /translation="MDNKKLKVKDLVSIGVFGVIYFAFMFGVGMMGLIPILFLIYPTV
                     LAIVAGTVVMLFMAKVQKPWALFIFGMISPLVMFAAGHTYVVVVLSLIVMIIAELIRK
                     IGNYNSFKYNMLSYAIFSTWICSSLMQMLLAKEKYMEWSLMTMGKDYVDVLEKLITYP
                     HMALVALGAFLGGILGAYIGKALLKKHFEKAGIV"
     gene            72906..73601
                     /locus_tag="VQ862_000077"
     CDS             72906..73601
                     /locus_tag="VQ862_000077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001141947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HET3114499.1"
                     /translation="MPTFSSNAPFNPNPISKILVVFITGLTVMHSINIRFELAIVCLI
                     GILLYLNGYKKTLFKWIILCGILYSLPNFMVLSELNPIVKMFLSIPIVIRMFILPFMA
                     ASFMIKTSDVGAIISSMDKLKISKNVSIPIAVMFRFFPSFKEEKKNIKMAMRVRGINF
                     KNPVKYLEYVSVPLLIISSNISDDIAKAAETKAIENPIAKTRYIRVKIQLIDFVYVLA
                     VVGLIVGGLIWLK"
     gene            73589..74953
                     /locus_tag="VQ862_000078"
     CDS             73589..74953
                     /locus_tag="VQ862_000078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002837029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3114500.1"
                     /translation="MVEIKNLSLDYGEEHILDDISLSIAEGECVLFTGKSGNGKSSLI
                     NSINGLAVRYDNAKTKGEIIIDGKNIKNLELYQISMLVSTVFQNPKTYFFNVNTTLEL
                     LFYLENIGLAREEMDRRLKDMLKIFPIKNLLNRNIFNLSGGEKQILCIAASYIAGTKI
                     IVMDEPSSNLDIKSISVLAKMLKILKEKGISIIVAEHRIYYLMDIVDRVFLIDKGKLK
                     KTYTRSEFLKLDKNELNALSLRDKELSKLKVPYLKEGGEYQIKNLSYKFTDDECLSLK
                     DISFKLGKIYGIIGSNGRGKSTLLRCLIGLEKKSKEEIYFKGEKLSKKERLKNSSLVM
                     QDVNHQLFTDEVFNELRLGVKNFDEEKAKIILKDLGLDEFIERHPMSLSGGQKQRLAI
                     ASVMCKTSPFVFFDEPSSGMDYSNMIKISELINKYKTMDKIIFIVSHDIEFLNEVADE
                     IFEL"
BASE COUNT        23236 a        16039 c        13683 g        22429 t
ORIGIN      
        1 acaacctcaa aacactgttt tgagcagcct gcggctagct tcctagtttg ctctttgatt
       61 ttcattgagt ataaacttct tttcacaaaa aggatatgaa accctctggt caagagtttc
      121 cccatcctat cttctattct ttattttgct tctacacgga caccttgggt atcaactctc
      181 aagtcatgca gttttccttt gaaaggttgc ttttccaatt ctgccttaat tgttggcatc
      241 ttgtcatgag aagccagaac cataactgtc ggcccagcac cagaaaggta ggttgcatag
      301 gccccatttt ctttggtcac ttgcttaatc atcgcaaatt ctcttaccaa gtcctgacga
      361 tagcgctcat ggaagaggtc tccctcgatt gcttgcccag cggtcaccat gtctcctgcc
      421 aacaaggcag caaccgctac attggcgata gaacttgcag caacagcttc cttataagac
      481 aattttttag gcaagacact acggctgtcg cgagtacgta attcatagtt tggaatgtaa
      541 gctagaaaat cacactctgg aaagtctgct acgatagcag agacttgccc ttcaacagaa
      601 cttgcaataa cgagattacc ataaatggct ggagccacat tgtcaggatg cccttcaatc
      661 ttggtcgcta actgcaattt ttcatggtct gataagttga gttgacccag ttggttggct
      721 agttcaatcc cagcaacgat aaccgagctg gaagaaccca aaccgcgcgc caaagggaca
      781 tcactggtca ttttcaagcg tcttggttgc aagtctggta caatttgcaa agcgattttg
      841 agcaagagat tacgctcatc atgtggaatc catttgccaa tctggtgttc aatcagccac
      901 tcatctcgtt cttcgcagac ctcaatttga agatacttgg ttacagctac accgaccgag
      961 tcaaaacctg gcccgatatt ggcactggtt gcaggtacaa taatcttcat cttattctcc
     1021 tagcaccttg aaggtattca agaggtcgaa ttctgaaacc ttcttcaatt cagctgagac
     1081 attttcaagc tgggctttat taatcttgtg tgtgatgata acgacacgcg ccttgtcacc
     1141 ctctttgcca tcttgaagga tttgcttaaa ggaaatatct tgagcattga agatttcagc
     1201 caacttcaag acctgacctt ttgagtctag agccaagatt gagaaatagt agtttgcttt
     1261 gacatcttca ggatttgcca agaccaagtc acggctatat tcgttgaagt ctttgccaat
     1321 agtaccatca ttcaaacgac gaacgatacg gacaatatca gctacaacac ttgttgcagt
     1381 tggtttttga ccagcacctg gtccgtagta catagactca ccaataccga tagattctac
     1441 aaagacagcg ttcattacgc cattcacact agcaagtggg tgcgctttag gtaggaaggt
     1501 tggagtcact tctgcagcaa tacctgaaga agtttcctca atagaaccaa ccaatttcac
     1561 tacgtaacca agctcttgag ctacagctac gtcttctggt gtgatattgc ggattccctt
     1621 gtgggctaca tcatcaaagg caatcttcat gccaaaggca aattggctca aaataaccat
     1681 cttgtaggct gcatcaatcc catctacgtc attcgtcgga tcgctttctg caaatcctag
     1741 acgttgtgct tccgcaagag catcatcgta agaccagcct tcttccacca tcttggtcac
     1801 catgaagttg gaagttccgt tgactactcc aagcacgcgc gtaattttat cagaagccaa
     1861 ggaatttgct aaagtacgaa gaattggaat cccaccagca actgctgctt cgtagtaaag
     1921 tgctaccttg ttagcttgag cgatttctag caattctgcg ccatggacag ctaaaaggtc
     1981 cttgttagca gtaacaacgt gttttccagc ttccaaggca cgagtgataa aggttttagc
     2041 aggctcaata cgccccatca attccactac gatagtaata tcctggtctg ataaaatatc
     2101 atccacattg gttacaaagt taaagtcatt ccctgctgca agcaagcgat ttttttcatc
     2161 ttcatccttg accaatacct tagcaacttt gatatctgaa tgtgctgatt gattaatttt
     2221 tcctccattt tcctttagga ggaaaggcac accacttgca acggtaccaa atcctagtaa
     2281 agcaatttta actgtcatct ttatctcctc gaaattttct aatatagcca ttataacaga
     2341 attttgtgaa aattcctatt atagtaaatc actatttcag tataaaaaga aaaaacgaat
     2401 cagacgattc gctcttctta aaatctgaaa atagctttcc agaaaggatt agccgatttt
     2461 ttgcagattg agcactgcat cgtgactcat caagacttga ccatactctt gtaagactga
     2521 gcgactgata tcactatcgt ctgcaaactc gcgcatacgg gccaacagcc aagctggata
     2581 tgggcttgga tgattttcaa tatccactaa aatggtcaaa taatagcgct cgttcatttt
     2641 gtagagttca gaagtttcca tttcaaaagt cactgtcttg gcaaaagcta ccaagtcagc
     2701 caacttagca aaagaaagga tgtagtagat gtaaggttct ttcttactct cagcttcttg
     2761 ttcagcctgc tcttgctctt cttccttggc ttcaacttgc tcaagagatt gaatggcttc
     2821 gatatcatcc ttggttttgt ctgctatgct tttttccagg gttttgataa attcatctgg
     2881 agacatttga gccaattctt ccatatctgg caaatccgat aagtcttcaa aatctagatt
     2941 ttggtcaatc tttgacttgg tcacaaagac atctacctta tcaggttttg gagtcacacg
     3001 gaagctcaac atgcctgtat ccagaaagct atcaggcatc tctagctcat ccaagatagc
     3061 ataaaagaac tcttctgttt tttcttgagg aacgagaaag tcagcaatct ccattccacg
     3121 atccatcaaa tcctctaaag acatcgtgat ttttaaagtt gtatcactaa tttgtttcat
     3181 tttcattgct agtaacctca tactttcagt tctatctatt atactagatt tttacgattt
     3241 tatcaaaaga aggctcctct atacggatag attttcccta gggtctttct ataggagact
     3301 ccaaaagaaa atttctgcag acagatagaa aaagccttca aaatcggctc ttagccgatt
     3361 ttgaagacct tatacatcag aatacttata atttaaaggt tgctacaccg aggatagaac
     3421 gatttaagtt tctgagaatt tgaagacttt gctcaaattt cttataacga gtcactccgt
     3481 actcttcaac aagaaggact gtatctcttt ccaaaagaga tgatacatcc tgtaaatcta
     3541 caaaatgcat tccttttaaa gcttcttgac tctgtttcaa tttatctagg atagctttat
     3601 ttgagctaac gatggtcaat tcctgtccag tatttttgta tgacaaaaca tctgctaggt
     3661 tagcaattgt tgtaatctct gttacaaaat caatttgata ctgagaaaaa tcacctactc
     3721 tattgattgt tggattaaag agataaacta acacatttcc catcacaacc aaaatcacac
     3781 aaaccactcc aataacaact aaacgaagaa tcagattttt cacatttaag ccaagcgctg
     3841 tttcaccatt tgcgttcaat tctttagagt tgatggtttc cagtttttca attttcacat
     3901 ttgcataggc atgtttaaat ttctcaatca acccatcaat ttttttctct aacaagtcat
     3961 tggcatcttt acttgatgtc aaaattttca caccaacccc tgcatcgtca atcatatagt
     4021 agacggtcaa ttttttccac caatagtcat tcgttgaatt tttcaaggtt gtttctgtcg
     4081 tgtctaattc actggcaatt tttttcaact cactgggttc tacatcattg aaaagataag
     4141 ctccattcaa attaccatca atcaatttcc cataaaaatc actataacca ccaatttgat
     4201 gattcaaaat cgttttggcc gactcttttg gaggagtgat tttatagata agataagttg
     4261 aataacttgt tgtatctttg acagtgtttt tattcctaac tgctttaatt gtaaatggta
     4321 cagcaatgag agcaaataaa gcgatgagag ctaaaatatt tgcttttcgc tttttataaa
     4381 gatttgcaaa caaatcagct actgaataat gttcaaacat gatttttttc tcctttgttt
     4441 agtagatact agttttcctt tgtaagcatt tttgctacaa atataatcac aagaacaatt
     4501 ccccagaatt gcattgtaaa taaattgaag aaactttctg aaaagctgct tcttggcata
     4561 aagaatagat tattcaagat gagtagggat aaagcaaata ggattgtcct tgagcgatag
     4621 gctacttgca gcatggctat aaataatacg ccgagtaaga aactaagcag aaagactcca
     4681 atcataccat agtcggtata caactccatg atataactac ttccgatacc atgccctttc
     4741 aagtattcct tgttcaagac aagataggat agattgtggg cataactatt actatcaata
     4801 gctagttcca cactattggt tgtatgttca aaggcttttc ctccgaaaat ggctcccaaa
     4861 ctcccccttg caaaataatc aagaacagga ccaaaagtaa aattacggaa atctcggtaa
     4921 gggaggctac tgttaaatag aaaacctcga gccagaacac caaaactagt tccttgttta
     4981 tagataaagt caagtaagat atcccagaaa cctgtatggg aaacttggac attatcccgt
     5041 acataattaa gtactcccat cgctaacatg agaataggag aacctacaaa aatcgctaac
     5101 ttttctttaa acccaatcca ttttcctttt tcagtttgct cccgcataaa gtaataaaca
     5161 aaagcaaata aaatacttaa aataaaggga tttcgtgtcc caattgccaa atgaatagta
     5221 ttagctgcaa taaaggagac aagcactgct gtggcctgca atttctttgg cttggttgcc
     5281 agatacatac acattgcata gaccgtaaag gtagacaaaa tgtaggtaaa ataaggcagt
     5341 ttactttcaa aatttgcata gtaggcatag taggaagtct gcaaacgata caagagccgt
     5401 tcaaataacc gaatgaaata gaaaggatag gttagaagaa aaactcctag tgatacaaag
     5461 cgtaaccgct tgatataaac ctcttttaga gaatttccta tatttgctac ttttattttc
     5521 ttcctagcta tgaagtaacg agccaggacg cctcctgtgg tcaagcccag aatcgaaacc
     5581 atgacaacta taaaggcaaa acgataggct attggatgat aggtatccaa agcaccatcc
     5641 ctaaaataat caatggtcgg tcttgatacc agaaatacaa aaatggttaa atagaaaata
     5701 aaatggatta agtaatactt gatatcattc caacaagcaa ttaagctact aaccaacaag
     5761 aacaataaag tagaaagtaa gctaacatta ttattattaa acagatacac aattccactt
     5821 actagcgtca aggtataact gactatggtc aaactaaata ataatcgttt cccatcaatc
     5881 acttggtcac ccccgttcta atgtaatttt ttagattttt caatattttt cagtaataag
     5941 aatcggtata aggaaatatt tatgaatagg gccaaagcac taattcttct ccccttacgg
     6001 aaaattggat tcctagaaat agcaaaagca tagcctttta aaaaacgatg aatctgagaa
     6061 taggcttcaa actgtttata ctgatcatct agcaacatct tatccagaat aaagaagtga
     6121 gcataggcca atctgaaaaa agcgacctct ttcaagtcag gatagttttt cacaacttca
     6181 ttataaaact tttggtagat atcaatatag gctaaatcct tctttgcata gggtttggtc
     6241 gtaatactat cccctctatg gaaatagtaa taatagggtt tagtattaac cacatacttc
     6301 ttggccaact tgattaaatc aaaatggtaa taggcatctt cgtaaatcaa ccccttagga
     6361 aaggataggg cagttgcaat ttgtctcttg attagcttat tgcaaatcgt cccaggtatt
     6421 ttttcaccta tgaggtattc ctttagaaat gtttgagaat cacagacaaa atagtcatcc
     6481 tgattggctg actgtgggct ttcatcatta gcatagacat tcatgacacc acagcttgaa
     6541 acatccgcat cttcttgaac taattgctca tataagctct gaatcatttc tggatggata
     6601 taatcatctg agtcaataaa aatcagataa tccccgtgag cctgcttcat cccatcattt
     6661 cgtgcttgcg acaatccttc gttcttttta tgaagcactg acaccctgtc atcttgttca
     6721 gcgattgaat cacacaagcg accactttca tctgttgcac catcatcaac aagaataatt
     6781 tccagatttt gataggtctg cttctgaatg gaagctatcg atttttctag gtactgcgcc
     6841 acattataga ctggcacaat cacactaatt aatgcagttt ccatgctact cctctaatag
     6901 tttttctact tgttcgattt gttttgtaat tgtaaattgt tgaatgaatt ggctagcctc
     6961 atcgacatta aagtttgagg cagaagtcat gtaattagta atcgcctgag ctgcctcttg
     7021 attgctctca atgatttgtc caaatcgtcc ttcttgggat aattcctcag cccctccaac
     7081 gtccgtagag ataaaaggga gtcccagact caaggcctcc acatacactc caggaaagcc
     7141 ttcttgttta gacatagaca agagaacttt cgtctgagat aaatactgat aaggattttt
     7201 ttgataacca aggaaatgta catagtcctc aatctcatac tctttgactc gttttttcag
     7261 ttcctcttcc atatcaccag ccccgataaa atagagatga tagttttttc cctcttggtg
     7321 taataatcgt atcacttcca ctacacggtc agaaccctta ttttcctcaa tccgtccgat
     7381 agtacagata ctttgaggag caatctcgat atcgatcttc tcttgagatt tttctagaat
     7441 agtctgaaaa tcatatccat tgtagattgt ctgtaattta gaagcataat ctggataaac
     7501 ttccttgata gaattgctgg tcttttttga aatccctaca attgtattcg cagcatccaa
     7561 ctggcttcta tgtgattctc ttttagagct atccttaaga agttcttcaa tacttccatg
     7621 aatccaagat atcttcttga cttctcttct tttagagaac aacagtggtg gattcataat
     7681 ggtaaaagaa acttcaacat cataatcatc ttttacaagc aaacgacgag tcagtcttgg
     7741 aaaataaatt ctcattctcc acaaaaaagc tcgtaaccat ctggtttggc gataatcttg
     7801 aagggatttt aaaatgcgta catgctttgg aacagattca tatcccttgt caaagtgctc
     7861 catttcaaga atatcaatat catacttttc tggatccaga tttgaaacaa tggttgatag
     7921 aatcttctct gcaccacctc caagagaaaa agaccacata aaaaataaga tttttttctt
     7981 agccaccata ttctcccttg tattctgtat aagacttatc catatcagcg atgacagcat
     8041 catgatgcgg taccttcttg tctgctggtg gaggcgtcat ataatcccca aaagcagttc
     8101 tgagatagac atcatagccg attggaatag gcatctctgt tccttcaaat ggcaagaaaa
     8161 gattgtcttc aaaagacgtg attgggtact tgtttctcat gtagccagga cctgagcata
     8221 attctgtaat gccatcacaa tcagccaaat catacttagt catttctttc tcagcttttt
     8281 tccagatgcg ataacggaga gattttggag tcaaacccag taaaatgcga cttccccatt
     8341 tcatgagagc accatgcttt tctggaatag tttgcgcaca aaagagtgaa taaatcaagg
     8401 cccaacgaac ctgttttttc cgctcagctg gatttttcgg ataataatcc aaaggcaaaa
     8461 catccaaggc cagaccatgt ggcaaatcca aatcctgctg ataaggcttg atacaggtgg
     8521 tttccttgtc acgaatggta ataaaaagat tacgatcaac aaaatccttg tgactctttg
     8581 acaagaaata acgttcatct gcataacgag gccataattc tgctaatttc tcataatctt
     8641 tacgaggcat aaaaaagtct aggtcgtcgt cccaaggaat aaatcccttg tttcgaaggg
     8701 caccaatagc gcctccgcca cagagataac agagcaaatc atgttcttta caaaaggcca
     8761 caaaatattc agccatctcc agactacgag cctgaattgc ttttaaatca gtcatattgt
     8821 tcattattct ttctatcgta tcgtttcatt ataccacaaa caaggggtga aaatctattg
     8881 cagactgtaa aaaatcaaag cctgactgct atccaaatag ctatcaaact ttgatttttc
     8941 tgtcttatac tcttcgaaaa tctcttcaaa ccacgtcagc ttcaccttgc cgtaggtata
     9001 ggtaactgac ttcgtcagtc ttatctacaa cctcaaaact gtgtttttag cagcctgcgg
     9061 ctagcttcct agtttgcact ttgattttca ttgagtatta tcttatctca agcccatttg
     9121 agcgagcttg gtttgatatt tgttttgatc aaccagcaag cccaagcctc cataaacatc
     9181 ataggcatct acccagtcac ccagttctgg aatcgtcaat ttttcaatac cattttttgc
     9241 tccatccaaa acagataaac cgtttgttag gaggaaagta tagggtacgt tggttgaggt
     9301 catagcaaaa acctttccaa gagcttcaga accagtgaaa agtttagtgg gatctttaat
     9361 ttgctctaaa attgctgtta aaacttgttg ctgtcttttt gtacggccgt aatccgcctc
     9421 atcatcatca cggaaacgag cataattgag cagggtcgag ccattcatct gctgttttcc
     9481 gactttaatg gtttgggttg gagactcagt ctcggtagcg tataaatcat ctccgactgt
     9541 agcttctgtt aggggacgcc cattcaatgt tgaaaattga gcatcaatcg tcaccccatc
     9601 agggaaaagc gtgtcaatcg ctgtggcaaa ggcctggaaa tcaaccaagg cgtagtactt
     9661 aatgtccaag tcaaaattat ctttcaagac ttggcgaacc atttctgccc ctttttgccc
     9721 ctcttgttct cctaactcgt aggctacgtt taacttgtta tctgtctgtt ttctaccgtt
     9781 aatcacttga ctataaccat ctatatagac caaattatca cgcatgaaac tgactagctt
     9841 cattttctta tctgagcccc cgacatttaa taccataata gagtcagttc gtgtctcaac
     9901 actgttctgg ccgattcgac catcagtacc catgattaaa atattaactc catctctagt
     9961 gtcctgacca ttaaagactt ctacttgagc tgcccgggca tcagcagttt tctttgcgct
    10021 agcatcttgg taaccacgca aaaacatgaa taccatggcc aaagccacac agaccaaaag
    10081 tgaaaaaatc accataaaaa ttcgtttaag acggagcttc cgtcttttct tttttggagg
    10141 gaaagagagt gcttgtgatt tggattgtga gcgactccgg ttcgcatagc ttggtaagtc
    10201 aacctgctct tctctttctt gttccaagct agagctacta tttcccctag caagagttag
    10261 cttttcttgc aaataggcaa actcattttt ttctctctca ttgagatagt gaatattttt
    10321 tagcaaataa tcataacgca actgctcatg atgacttaag ggattttctt tactcatctt
    10381 ctctcctttc catggtctga tattggataa ataggatagg cacccagaat tttatactgg
    10441 attccaatcg cttctaattc tttttgggca aagtggacca agtccttatc ggtataatcc
    10501 acatcgataa tgaaaaagta ttcacccagt gctgtcttga gtggacgact ttcaattttt
    10561 gtcaagtcaa ttcctcgcca agcaaaggtc gacagggcct tataaagtgc acctggaagg
    10621 ttgtcaggta atgtcaaggc caaactcatc ttttcagttt gtgcttgcaa gggaatacta
    10681 ggcttttcag ctcctagaac ccagaaacgt gtgaaattgg cttccatttc ctgaatatcc
    10741 tcggcaatca gttccaatcc atattcttca gcagaacttc taggtgcaac tgctgcaaag
    10801 ggctggtctg gatgttcgga aataaaacgg gccgcataag ctgtactagc tgttacctcg
    10861 atttgagcct ctggatattg ttcatcgatg aatttctttc cttgagccaa ggcctgtgga
    10921 tgtgaaaaaa tcttttcaat cttagtatgg cctggaacca ccatcaactg ctgatgaata
    10981 ggctgaacga tttctgctac tgcttggatg tgagcctgat gaaaaagata gtccaaggtt
    11041 tcatgaacac taccctcaat agaattttca actggcacca cagaatagtc cactaatcct
    11101 tgctcataag ccttgatgac atctgtaatg ttagcaaaag cctgcaattc ctcatgagga
    11161 aaagctatct gcacaacgtg gtgtgaaaat gatcccttgg gacctagata agcaattttc
    11221 atcttagttc ctctataatt tcctctgggc ttagcttggt cacatccaaa acccgactag
    11281 ccacttcctc ataccaagcc tgtctttctt gaaaaatagc tactagttct tccttgctat
    11341 tatttagaaa aagcggtcgc tgattgtcct tatcagctgc gatacgttgg tagagggttt
    11401 caaaatctgc tttcaggtag atgttatctg tattagtctt gagtaagtca cgatttctct
    11461 gagaaataac cactcctcct ccagttgaca cgacttggtc tgtttgtagt aaatcagcta
    11521 ggacttctga ttctacctga cgaaaggctg cttctccctt ttcagcgaaa aaattcgcaa
    11581 tggacatacc taggcgcttc tcaatcagag catccatatc aaggtaatta gggtccaagc
    11641 ctcttgcaat agtcgatttt ccagccccca taaaccctaa taacacctta gccatgaatc
    11701 aagctctcca aatcatcaaa gaaactagga tagctggtat tgatggcttc tgcacggtca
    11761 agctccacct ctccatctgc aaccaagagg gctgcgatag ctgtcatcat gccgatacgg
    11821 tggtcaccaa acgtattgac tctagcaccg tgaagagctg atttcccttt gataatcatc
    11881 ccatctgccg taggagtaat atctgctccc atactattta aggcgtctgc cacaacctga
    11941 atacggtctg tttccttgac cttgagctcc tcagcatcct tgataactgt tacaccttgg
    12001 gcttgagtcg caagcagggc aataatgggc aattcatcaa tcaatcgtgg aatcaaagcg
    12061 ccaccaatct ctgttccttt caagtcagaa gactcaacag tcaaggtaga agatttagcg
    12121 actggatcga tttcagttat ttccaatttt ccacccatgg cacgaatgac atcaataata
    12181 ccggtgcgag tttcgttgat ccccacattc tgcagcacta gacgagaatt tggaacaatc
    12241 aaacctgcga ctaaccaaaa ggctgcactg gaaatatctc ctggtacgac caccttctgt
    12301 cctgtcaatt tttgtggccc ttggactgtg attttcttac cgtccacact taaatgacca
    12361 ccaaattgtt tcaacatatc ttcagtatga ttacgggtgc actctttttc gataataact
    12421 gactccccct tagcttgtaa ggctgcaaac atcaaggctg acttgacttg ggcagaggca
    12481 attggcaact cataatgaat aggtcttagg tttttcgtcc cttttaagcg aaggggaggc
    12541 aagtctcgtt cagtttgccc tgaaatgctg acgcccattt ttttcagtgg aagggtcaca
    12601 cggtccatag gacgtttgga aagactatca tctccaaaca tctctacttc gaaatctgca
    12661 ccagcaagga cacctgaaat caggcgaatc gaggtgccag aatttcccat attaagggca
    12721 ttttgtggcg cttttaagcc agccatgcct acaccttgaa tggtaataac cccatcttta
    12781 tcctcaattt caacaccaag gtcacgaaaa acctgcatgg tcgaaagaac gtcttcacct
    12841 cgcagaatat cataaacctt ggtctcaccc tcagccaaac ttccaaagat aatggaacgg
    12901 tggctgatag acttgtcacc tgggacgcgg atactaccat gtaaatggcg aatgtttgtt
    12961 tttagtttca tactggacct catacttgca atacttttac ctattttatc ataaaaagcc
    13021 agaaattcct taaaaattcc tgactttagg atcgttcttt tcttatttca gcaattctga
    13081 aactggttca aaaacaattt tttcaatgtc agaaaggtaa atggccaatt gttgttgctt
    13141 ggtaaagaat tctgacaaga ggctatttcc ttgaatctgt ttaccaaagc cttccatctt
    13201 agcttggaag gacgcatctg gcatttgacc tgtatgtgct agtttttgaa tttcctcttg
    13261 aaaggcaaga tattctgtaa agattttgct tgcctcagca tctgctgcaa tcgcatcttt
    13321 agctgcttta acagccttgt attctggtaa tccgcgtaga ccgcgactga gttcgtttgc
    13381 actatcgtaa atatttgaca tgttcttctc cttatttgat gacgactgta tagtcggtat
    13441 tttctgttat gagatgctca gctctttcca agtcttgagc atttttaaat gaaatttgta
    13501 ggattccgtg aatatcctca cgattttcct cgttgatgtg gatgttaacc aaggaagtcc
    13561 cacgtagcag ttccaaaatc cgcaggatga catcttcttc atcaggaacg tcaacataga
    13621 ggtcgtaaga gctatccaca ccaccacgct tatggatttc catggtctgg cgttgttcac
    13681 gcgcttggtt aaaaaagttc caaatttgct cttcatctcc cttactaatg gcctgaccaa
    13741 tcacttccaa acgttccttg aaatcctcaa ttctatccag aatggtctcg ctattggaca
    13801 agagaatgga ggtccacatt cctggctcgc tttccgcaat tcgggtcata tctcgaaaac
    13861 cacctgccgc aaagcgcctt gccatctcat gctcttgagc atagaccgca gtctgctcca
    13921 tgagactaga agccaaaata tgaggaaaat ggctaatctg agaagtgaca cgatcatgct
    13981 ccttggcatc aatctcgata aaacgagcat gaagacctga aagcagatcc ttcatttcct
    14041 taagcgtgtc ctgacttgtc aggcttgaag gtgtaaagat ataataggca ttttcaaaaa
    14101 gattgacatc tgccgaagca gcccctgtct tgtgactacc agccatggga tgggccccga
    14161 caaagcgaac agacttgcca gccaaatact gctccgccgc atccacaatg gttgacttgg
    14221 tcgaaccagc atctgaaata ataacgcctt ctcgcaaatc caaattggcc aactccttaa
    14281 tgaaagcaat agtttgtttg attggcaagc tgaggataat gacatctgcc aaaggagcaa
    14341 aactagcaaa atcatccgtt gcacggtcaa tcatgccttc tttcaaggcg atatctctcg
    14401 aagcttgact acgattataa cctaaaattt cataatctgg atgatcgcgt ttgataccaa
    14461 gtgccataga ggctccaatc aacccaagac ctgcgatata gattgttttt gccataggaa
    14521 ctccttaata gttctttgta tagtctcggt gtttggctac cgcttctttt agttcctcaa
    14581 gattatctga tgagaatttt tcgaggattt cttgcgccag aaccgttgct acaactgctt
    14641 ccatgaccat tcctgcagct ggaagagcag tcggatcact tctctccacg gttgccttgt
    14701 aaggttcgtg ggtttcgata tccacactca taagaggttt ataaagagta ggaatgggtt
    14761 tcatgacccc acgaacaacg atgggttgcc cattagtcat accaccttca aaaccaccta
    14821 gattattggt acggcgagta taaccgtctt ctttagacca gagaatttca tccataactt
    14881 ggctgccttt acgataacca gcctcaaagc caagaccaaa ttccacccct ttaaaggcat
    14941 tgatagagac aacagcttga gccaatcttg catccaattt tctatcccat tggacatagg
    15001 aaccaagacc aactggaacg cctccgacga ctgtctccac aaccccaccg atggtatcac
    15061 catcacgttt gatttggtca atatagtcct tgatttcctg ttctcgttct tggttaacaa
    15121 tagaaacttc agactgggca gctctttgct taatttcagc gactgtcaga ttttcaggaa
    15181 catcgatttc cttgccacca aagaccacga catggttggc aatctccata tccagctcag
    15241 ccaagaggcg tttggctact gcaccaactg ccacccgcat ggtggtttca cgagctgatg
    15301 aacgctccaa agaatttcgc aaatcatcaa aacggtactt aatcccccca accaaatcgg
    15361 catgacctgg gcgaggatga gtaattttcc gcttgctttt aaggcggtct tcaatgtcct
    15421 ccgcagacat gatgtccagc catttctggt ggtccttatt gatgacatcc atagtaatag
    15481 gcgcccctgt cgtcttcccg tggcgaacgc ccgaagtaaa gacaacctgg tcactctcaa
    15541 tcttcatacg accaccacga ccgtagccac cctgacggcg tctaaggtcc tcattgatat
    15601 cctcagctgt caatggaagt ccagctggaa ttccctcaat aatagctgtt agacgggggc
    15661 cgtgtgattc tcctgcagtt aaatatctca tacactctcc ttattttacc aagtagtctt
    15721 tcatctcttc cagagaaact gggtgaatga tcgctgaacc aagctctggc accaagacca
    15781 atttcaaggt gttaccacgc gctttcttgt catgagtaag agcctgataa agcttgtcaa
    15841 cttcccaatt ttcatagtca acaggcaagc cgaatttctg acacatctct gtgatagatt
    15901 gggtaatgcc agctggcatg aggccttttt cctcagcaac cttggaaatc tgtaccattc
    15961 ccatggcaac agcctctcca tgcatgacct tgccataacc ggcagtcgct tcgatggcat
    16021 ggccaatagt gtggccaaaa ttgaggtaaa gacgaatacc attgtccaac tcatcttcaa
    16081 ccaccatctt gcgcttcacc tgacaagaat gttcaatcaa ggtctctgca tgttccaaaa
    16141 tactctcaac agaaccattc agtcccgtca agagagccca cagttctgga tcctcaatca
    16201 agccatactt gataacttca cccatccctt caatcaactc tctttttccg agggtttcaa
    16261 gaacaagtgg atcaatcaga accccatctg gttgggcaaa ggtccccacc atatttttag
    16321 caaatggtgt gttaacgcct gtctttccac cgatagaaga atcaacctga gctgtcaaac
    16381 tagtcggaat ctgaacaaag tgaatacccc gcatataggt agaggctaca aatccagcca
    16441 ggtccccaac aacgccacca ccaagagcaa cgattccatc gctacgagtc agaccttgct
    16501 tgactagaaa ttcatagact ttctgaacag tagttaaatt ctttctttct tcaccttcta
    16561 agaaatcaaa aacagctacc tgaaaaccag catcttctag gctgagcttg accttctctg
    16621 catagagaga ggctacatgg ttatctgtca caatgactac cttttgcggt tgccagagtt
    16681 ctcgcaacca ctgaccagcc tgggccatac aacctttttc aatctgaata tcataaggat
    16741 gatgaggaat atcgattctg attttcatag gagagtttcc ctttctttat tggtattttt
    16801 ctgttaaaga ctgccaaatc tcttctgtcg gcatttcctt gcctgtccac agttgaaaag
    16861 cttctgcagc ttgatagagt aacattccca gaccattgac tgctggattg ccctgacttc
    16921 tagcccattt caaaaacggt gtttcaaagg gttggtatat gatatctgca actaaaagag
    16981 tttctggtaa gactatgttt tcaggaacag gagaggattg gccatccatg cccacactgg
    17041 tggcattaac tagcaaatcc gactcggcaa tccttgcttg cagttcagaa acatattcta
    17101 aagcacacaa atccacttta aaacctgtct gctcctgtaa cttgtctagg taaggtcttg
    17161 ttttttccat agaaacggaa cgaacaaaga ccgaaatctg actgacgcca tccaaaatag
    17221 cctgtgccaa gattgattta gccgcaccac ctgcacccag cagggtcatc tttttacctg
    17281 aaattgtaaa agaaggcaag cacttaaaaa atcccttgcc atctgtatta tatccaatta
    17341 aattgccatt ctcattgaca accgtattaa ccgcaccaat caagcgcgct tcatcgctca
    17401 gcttatccaa ataaggaatc acctgctcct tatagggcat ggacagattg atgccaaaca
    17461 tctggtagcg acgaatattg gccactgttt ctaccaagtc actcgcttca atctcccaag
    17521 ccacataagc accgttggta tctgtcgcct caaaggctct attgtggatg aagggagaaa
    17581 tagaatgctt aataggattg gcaacaactg cagctaaacg tgtatagcca tcaagcttca
    17641 tccaaaatct ccctgatttt tttcatgcta gctagagaaa tctgcccagg ggcactaacc
    17701 tcatccagac tggcaaaaga ccaactcgaa ccagtcacat ccgcagtgat acgagagacc
    17761 ttgcccacct tacccataga aatggtcaca tattcctgtt caggattgag ggttttaaag
    17821 cctcgtgtat agttcatcaa gtctaagaca tcctgctccg tgtgagccat caccgcaacc
    17881 ttaacaagtt ttggatttag gatcgtcaac tctgacaaga tttccatcat gttctcaggt
    17941 gtttcttgga aattatggta actcaaaaca agatttggga agtccagcat ttcctcaaaa
    18001 acatccttgt agctatagta ctcaaaatca atatagtctg gttgatagag ttgcgcaact
    18061 tccttgatta gatggatata ctcttctgga gaaaggtcga tttctccacc ttcggagcga
    18121 gttcgtagcg tgaaaaccaa ctcacggcct gcgaattttt caaaaatggc tggagctacc
    18181 tgcaaaatcg cttctttagg cagatagtcg gcacgccatt caatgatgtc ggcatccagg
    18241 tacctcgtgt catccagagc ctgagcctcc tctaaacttc ttggcattac tgaaacgatt
    18301 aatttcattt actaaccttc atactaatca ccttgaggta attactactt tcatcttttt
    18361 tattataggc aaaatctgct ggaagaccat atttgtttaa aatctggtaa cttcttcctg
    18421 caaaaccttt atcaatttgt tctgtaaatt tctgacggga aacattggca gcattggtac
    18481 tggcaatgat aatccctccc ggatttaaaa tctcaagact ctgggaaatc aacttgtgat
    18541 aatccttggc cacagagaaa gtttgttttt tattccgagc aaagctaggc ggatctagga
    18601 caatcacatc gtaggtcaag tctttgcgtt tggcatattt gaaatactca aagacatcca
    18661 tgactataaa atgatgctcg tctgtgctga gcccatttgc ctgaaaatgc gcttgagaca
    18721 attctcgtga acgtttggct agatcaacag aagttgtctg gctagctcct cccatggccg
    18781 cagctactga aaaagccgct gtgtaggaaa acatattgag caaggattta cccatagcca
    18841 agccgtcaac taaactaccg cgaacctcat gctggtctag gaaaatgcct gtcatcaagc
    18901 catcattcat aaagacttga tacaggacac cattttctaa aacagtgaaa aagtcaggtg
    18961 cttcttgacc ataaacatgg gcagattcat agtccaaacc cttaaagcgg attttctcat
    19021 aagctcctaa aacctcaggg aaaacctgtc taaaggcttc tgatatagtc tgacgaatct
    19081 gataaacata agagttatac caagaaaaga cggcgtagtc gccataaagg tccactgtca
    19141 gacctccaaa gccatctccc tcttgattaa agagacgaaa ggcagttgtc aaatcatctt
    19201 gatagtaggc gtttctcttt tctttggctt ttctaaacaa cgtttcaaag aaagtttgat
    19261 tgaaggccac cttgtctttg ctgacaaacc agcccaagcc cttgttttgc tgagaaaggt
    19321 aggcagtccc aagaaagttt ccttcctgac cctgcacctc tacttcctga tccttaagat
    19381 tgacattctc aagatcactg gcttctagta aaactagccc cttagcaagc ttcttttcaa
    19441 cccttttgct gactcttatt ctattcataa ctaccattat atcaaacttt tagacaattc
    19501 tcaaaaaaga aactaccctt gcttttttac tcttctttta aaaaatggta tactagactt
    19561 cctgcaaaac taggaagtaa atgtgtaaga atcacaataa aaaatgctct tccgtcttgg
    19621 aggagcattt ctttttatca acgaaaatca aatagcaaac tatgaaacta gcctcaggtt
    19681 aactgtgaga ttataggtag agaggttgaa tcagcaatat gtgtctgtca aatttagtga
    19741 caaaggtagt agaagaaaga tgaagaaata aatctgcttc aataggtatc tggaaaattt
    19801 gattttatag agaagccttt tgttacaaac tcaatatact atcaataaat aatattatag
    19861 aagcaacaat aattataatt tcacctatct gcatcattct atttcgaact ctaaatatat
    19921 gttctatcaa aaatacttgg atcacacaca ttataggaat taacgttttt gaaattgaaa
    19981 aatatcccaa taaataaact ataaacaaca aaaatagaac tatgttatat ttcttattca
    20041 aaacattcct ccctatatat ttttgattac caatcttaat catttacaac tacattctaa
    20101 caaactataa aagcgtttgt cgaactgaat ttatcaagca agcgaccaac cagctcatct
    20161 tttttctatt tctgccaata tgcgtgacag gtaataatga tagccaaaaa tagcaagagc
    20221 aagcaggagg ataagagctc ctactcccaa gctgatggca aggatagggg agagagactg
    20281 aaccaagaat atactcccaa ttacaagggc catcaggatt gcactataaa taaacaataa
    20341 aactatggcg actatgccat ttgaacgatt caccaggtcc gtaatgctac tccaattggt
    20401 tgacagattt ttcacatcct taaaataatg gtgacaagaa aggatgacac tggcaaggat
    20461 ccatgccaca ataaggtaaa tcatcgaaat gatgggcaag cctagatata gagaaagacc
    20521 aagtaaagtc agaattggta aaaaggactg aacagcaaag ataatccaaa atttcacttt
    20581 cacataacga gcaaagtcaa agggtaaact cttcagaaaa tcaacatttt ccctctccaa
    20641 ggacaaggca attgaaggca ggctggtgat attgttattg acaactgcta taaagagagc
    20701 tataaaaaac aagggtaacc agtatggagg atgaatgtct ggaactatct gagaatctcg
    20761 gattttggaa atcagaccga tcatcatgag ataaggaagg aaagcacttg taaaaagcac
    20821 tgtaaccacg ccagtcccct gtcccaagag ggtgaggtgg tagcgtaaaa ccatgcggaa
    20881 aaatcccttt ttagtggttg aaattctctc cttgctgcga cgttcttttt tgaccttctc
    20941 ctcactatta agcaggatca cgtcataaaa acgaggaagg accttctttt tggtcagata
    21001 aagcaggaag agagttagtc ctatccaagc gagcagaccc aatatggctt ctattgaaaa
    21061 aggctccact gctattttgt aaaagatatg aagaggataa aggagaaatg gaatgtctct
    21121 aactttgtca acaatacttc caaaagtcga ctgaagaaag aagataaata ttaaaggtat
    21181 gagaactcct atcccaatca tcacattcga aaaaatagac tgatactttc tgaagaccct
    21241 agtctgagcc aagaaatgta ctgccactac cgtcactaaa gtaacagaga caaataataa
    21301 ggtcaaggac agtagcatca aaggcaaacc cagccaaaga gaaggagcta gactaatata
    21361 gagggctaga aaataagcta ggattggtac aattccagtt agagctggca agaggacaga
    21421 cagtccttta gcaattataa tctctgattc tttaaaagca tagggactat aggaggccaa
    21481 atccttactc tcataaaaga cattgtaaaa tgcagttaaa gaagttgaaa aggcaatcac
    21541 tagtaaaata gcaaccatga aactaaaata aacaggcatt tcctcaaaag gaaaatgaat
    21601 ggctatagta ctaaaaaaga tgagcatcaa gagactggaa aaaatgtaag aacttaggac
    21661 tctagcggaa acatttactt tttttccagt atttttagct tgcttctttc gtgggttagc
    21721 cagattagcg tcttgagatg aatagaggat attgatatca actaattttt taatgacctt
    21781 gagacgcatc tgaaacctcc tcttttctac cagcaaggct aaggtagata ctttccaaag
    21841 actggtctgg gttgtctttt ctcaagtcct ctaccttacc acaataaatc aaatgcccct
    21901 ttttcaaaat agcaatccga tcacagactt gctcagctac ctctagcaca tgagttgaaa
    21961 acaaaactgt cttacctttt tgcgcatgct ccttcatcat ttgcttcaaa tcaaaggcgg
    22021 cctggggatc caaaccagtc aagggttcgt ccaaaaccca aatatcagga tcagacaaga
    22081 gtgccccgat gacaaagact ttctgacgca ttccgtgaga aagagtttca ataacctgat
    22141 agcgattttc agcaaaatca aaaacgttca atagcctagc tagactagcc tccaagtcag
    22201 atctactcag atcataggat gaggcgatca attcccaaaa ttcattggcc gttaagcgta
    22261 aaaataagtc aggcgagtct gctacgtagc caatctttcg tttaatagcc aagcgatttt
    22321 ccgataactc ctgaccgtct accaaaatac gaccactgct gggtgaaatg atactgacta
    22381 gggattttat agtggtcgat tttccagccc cattatgacc aatcaagccc ataatctctc
    22441 cattttcaat ctgcaaattg agattactca aggcctcttt atcaccatac aacttactaa
    22501 cattttgaaa ttcaatcatg ggacaactcc tatctttatc tgtattatat atcgctatac
    22561 tatcactttg atacaaaaaa tcaatacttt attttaagta gttaaaacag tttccttcta
    22621 ttcttacgca aacgtttgcg ctaaccaata ctttatgata gaataaagaa caagattgac
    22681 aagtaagagg aaaaatcatg caaaatcaaa cgctcatgca atactttgaa tggtatctgc
    22741 cccacgacgg tcagcactgg acgcgtctgg ctgaagatgc tccacaccta gctcatctgg
    22801 ggattagcca cgtctggatg ccaccagctt ttaaggcaac caatgaaaaa gatgtcggct
    22861 atggtgtcta tgacttattt gacctaggag agtttaacca aaaagggact gtccgcacta
    22921 agtatggttt caaagaagac tatcttcaag ccattcaagc cctaaaagca cagggaattc
    22981 aacctatggc cgatgtggtt ctcaatcaca aggctgcagc cgatcacatg gaagcctttc
    23041 aggttatcga agtggatcct gtagaccgta cggttgaact tggagaaccc ttcaccatca
    23101 atggctggac tagctttacc ttctatggtc gccaagatac ctacaatgac ttccactggc
    23161 attggtacca cttcaccggt acagactacg atgcaaaacg ccgtaagtct gggatttatc
    23221 tcatccaagg ggacaacaag ggctgggcta acgaggaatt ggtcgataac gaaaacggaa
    23281 actacgacta cctcatgtat gccgacctag actttaaaca tcctgaagtc atccaaaaca
    23341 tctatgactg ggctgattgg ttcatggaaa cgactggtgt agctggtttc cgtttggatg
    23401 ccgttaagca tattgactct ttctttatgc gcaacttcat ccgcgatatg aaggaaaaat
    23461 acggtgacga tttctatgtt tttggtgaat tttggaaccc agacaaggaa gccaatctgg
    23521 actatctcga aaaaacggaa gaacactttg accttgtcga tgttcgtctc caccagaatc
    23581 tctttgaagc cagtcaagct ggcgcaaact atgaccttcg tggcattttc acagatagcc
    23641 tggttgaact caagcctgac aagtctgtga cttttgtcga caaccacgat acccaacgag
    23701 gacaagccct tgagtctacc gttgaagaat ggttcaagcc agcagcctat gccctcattt
    23761 tgttacgcca agacggcctt ccatgtgtct tttacggaga ctactatggg atttcaggcc
    23821 agtatgctca acaagatttc aaagaaatcc ttgaccgcct cctagccatc cgaaaagatt
    23881 tggcctatgg agaacaaaat gactactttg accatgctaa ctgtatcggt tgggtacgtt
    23941 caggtgctga aaatcaatcc ccaatcgcag tcttgatttc aaatgaccaa gaaaacagca
    24001 agtcaatgtt tgtcggtcaa gaatggacta atcaaacctt tgtagattta cttggtaacc
    24061 accaaggtca agttacaatt gatgaggaag gttatggaca attccctgtc tcagctagat
    24121 ccgtaagtgt ctgggcagtc aataccatct aatagctcat aataaccaag ctaggtccaa
    24181 gcggatttgg cttttttgta gtcaaaaaag acctacccaa atggatagat ctttacttga
    24241 ttacaattta cctgctacta catccaataa ttcttggatc ttagcttggt tgcttcctcc
    24301 tgccatggcc atgtctggtt taccaccacc acgtccatcg atgattggtg ctaattcttt
    24361 gacaaggttt cctgcatgaa ggtcttttgt cttgcttgct acaaggacat tgactttgtc
    24421 accgatagcg gcaactagga caagaagatc agagtagtct ttttgtttcc agttatctgc
    24481 aaaagtacga agggcaccgg catcggatac agacacttga ctagcaatgt aacgatgacc
    24541 gttgacttcc ttagcatctt tgaagatatc gcctgcggct gcagctgcgg ctttttcttt
    24601 caactcagca ttttcttttt gaagttgacg aagttgttct tgaagtcctt ctaccttgtg
    24661 aggtacttcc ttgacttgag gtgctttcaa ggttgctgcg acagctttaa gagcatcctc
    24721 ttgttcacga taggcttcaa aggcttcctt accagtcact gccaagatac ggcgagttcc
    24781 tgaaccgatt ccttcttctt tgacaatttt gaagagacca atctcagaag tgttgccaac
    24841 atgagtacca ccacaaagtt caatagagta gtcaccgata gtcacgacac gaacttcctt
    24901 gccgtatttc tcaccaaaga gggccatagc tcccatttct ttagcagtgt caatatccgt
    24961 ttcaactgtc ttcacttcaa gtgcttccca aattttctcg ttaacttgct gttcaatcgc
    25021 acgaagttcc tcagcagtta ctgcttggaa gtgggtaaag tcaaagcgaa ggaattcaac
    25081 ttcgttaaga gatcctgcct gtgttgcgtg gtttccaagg atattgtgaa gggcagcgtg
    25141 aagcaaatga gtcgcagtgt ggtttttcat gacacggtga cggcgattgc tatcaattac
    25201 caaggtatat tcttggttca aggcaagcgg tgcaaggact tcaactgtat gaagggcttg
    25261 accatttggg gctttctgaa cattggtcac agtagccaca accttacctg actcatccaa
    25321 gatttgtccg tagtcagcta cctgtccacc catttcagca taaaatgacg tttccgcaaa
    25381 gataagagag gcagttcctt ctgaaacagc ttctacttct gcattgtccg ccacgatagc
    25441 taccaattta gaagacaatt ggctagcatt gtagttgaag acactttcta cagtgatgtt
    25501 ttgaagagtt tcattttgca tacccattga gccacccttg acagctgagg cacgcgcgcg
    25561 ttcttgctgt tctttcatgg ctgcttcaaa accttcacgg tctacagtca taccagcttc
    25621 ttcagcgatt tcttcagtca attcaactgg gaacccataa gtatcataga gtttgaagac
    25681 atctgaacca gcgataacag attgaccttt ttctttcaag tctgctacaa tgccttgggc
    25741 aaagtgttga cctgagtgaa gggtacgggc aaatgattct tcttcgctct taacgatttt
    25801 ctcaataaag tcacgtttct caagcacttc tgggtagtag ctttccatga tttttccaac
    25861 agttggaacc aatttgtaaa ggaaaggttc gttgataccc aatttttgac catgcataga
    25921 agcacgacgg agaagacgac gaagaacata accacgacct tcatttcctg gaagggcacc
    25981 atcaccgata gcaaatgaaa gagaacgaat gtggtctgcg ataaccttga agctcatgtt
    26041 gtcgccatct tggtcataaa ccttaccaga caatttctcg acttcacgga taatcggcat
    26101 gaagaggtcc gtttcaaagt tggtcttagc cccttggata acagccacca aacgctccaa
    26161 accagcgccc gtatcaatgt tcttatgtgg caattccttg tattcgctac gaggaacagc
    26221 agggtctgcg ttaaattgtg acaaaacgat gttccagatt tcaatataac ggtcgttttc
    26281 aatatcttct gcaagcaggc gaagaccgat attttctggg tcaaaggctt ccccacggtc
    26341 aaagaagatt tctgtatctg gtccagaagg tcccgcaccg atttcccaga agttgtcctc
    26401 aattggaatc aagtgacttg gatccactcc cacttcaatc cagcggttgt aagaatcttt
    26461 atcgtctgga tagtaggtca tgtaaagttt ttcagcaggg aaatcaaacc attcagggct
    26521 tgtcaaaagc tcataagccc aagtgatagc ttcgtcacgg aagtaatccc cgatagagaa
    26581 gttccccagc atttcaaaca tggtatggtg acgcgcggtc ttccctacgt tttcgatgtc
    26641 gttggtacgg atagcctttt gggcattggt aatacgtgga ttttcaggga taatggtccc
    26701 gtcaaagtat ttcttaaggg ttgctacccc agagttgatc cacaaaagag ttgggtcatt
    26761 tacaggaacc aaacttactg atggttctac tgagtgacct ttggtcgccc agaaatcaag
    26821 ccacatttgg cgtacttgtg cactagatag ttgtttcata ttgtctcctt attcacttgt
    26881 ttaatgtgat tggctttcca gcatttccac atagtcaatc gcgacacaga gggaaatgac
    26941 taggtctgca taagcgtctt caagaaccgt tacggtatag gtagaggtca gatggaagag
    27001 ttccttctta atttccgcaa tcaactgatc gcgatcatcc agcaatttga aattcaaatc
    27061 ccagatattg ccctcgatac gaagacctag attatcaaac tcatacttat ctcgccagaa
    27121 ggtcaacttc ttacgaatga caaaactcga gccatcccga agctgaatct caaaacgagg
    27181 aagcaaggtc aagatttctt tactgatctg actgacttgt tcaccagccg catcatagat
    27241 ggtaaaagtt ttgggaatct taaaaaatga tccctccacc tgataggcaa tttctcccct
    27301 gtcatccttg atagcgaagc gttcgcctcc aagacgaaac ttttgtttga caagaaatgt
    27361 tttcatcaac acctccaaaa atcaaaagac aagctcatat cacgaagggc gaaaaaccgc
    27421 ggtaccacct tcattcaatg aacttgtcat tctcttgttc ttatgcaatt gtatgattga
    27481 gtagcatgac ttcctagctt agatggctcg cagcaccgcc atttctctgg actaagacaa
    27541 gtgaaaatca attctcaact ttcttattat aacgtttttt taagcttgcg tcaactggaa
    27601 atgatctccg ttgaattaga ccaattccct acatctctga ttactttttc aggatatatt
    27661 ttttcttact gccatttttc tttttatccc aaattttcat attactaaac acagctacta
    27721 gaatatttcc aaatataaag gtgcctatca cccaatatat ggactcagtt gttaggtatt
    27781 gtcgatccaa gccatccttt aaatggaata gtatagcagt ttggttaaca atcataaagg
    27841 ttggccagaa actatttttg aaaaaagtag acattttcat tatttgttgc cgctttctgt
    27901 aaggttaata ctcaataaaa atcaaaaagc aaactaggaa gctagcctca agctgtactt
    27961 gagtacggca aggcaacgct gacgtggttt gaagagtata ggcttagtat actactaggc
    28021 aagcaaataa gcaaataaac aaataaacaa ctagaataga aaaagatagg gctctaaaaa
    28081 ctgacttcta ttccttaaaa acgaaccagc ttgactgatt cgtcttctta cgtttatctc
    28141 ctacttccga tacattttaa actgtaggaa gaggtcgcta tatttccctg tccatttatg
    28201 gtcaaatttc tcataaactt ctaggtgttt catggtttca acatcgggat agaaggcctt
    28261 atcttccttt gtttcctctg ggagcaattc cttcgctggt aggtttggtg ttgaatagcc
    28321 gacatactcc gcattttgga gagcattttc aggtttcaac ataaagttga taaaggcata
    28381 ggctgagttt tggtttttaa ctgttttggg aatgaccata ttgtcaaacc aaagattgct
    28441 ggcctctgtc ggtaccacat aacgtagatt ttcatttttt tctaacattt ggctggcttc
    28501 accagagaag gtcacgccga ttgcaacatt attctgaatc atatagccct tcatctcgtc
    28561 cgcaacgata gccttgatat ttggagtcag tttgtagagc ttatccactg tctcttccaa
    28621 ctgctgcaga tccttggagt tgaggctgta gccgagggaa ttgagtccta gtcccagcac
    28681 ctcacgcgcc ccatcaaaga gcatgataga attcttatac tccggcttcc aaaggtcatc
    28741 ccaatgctca ggcgcttcat ctaccatggt ttcgttgtag acaattccta aggttcccca
    28801 gaagtaaggg atggagaatt tattacctgg gtcaaaggac tggttgagaa actctggtcc
    28861 gatattttcg attcctttaa tttttgaata atcaagcgga accaagaggt cttcgtcctt
    28921 catcttgtta atcatgtatt cacttggaat ggcaatatcg taggtcgttc caccctgctt
    28981 tatcttagtg tacatggctt cgttggagtc aaaagtctcg tactgaactt gaattcctgt
    29041 ttcttctgta aactgagtca agagttcagg atcgatatag tctccccagt tatagataac
    29101 caatttttga ctatctcgac tattgatttt actatctaaa tgagtcgcaa ttccccacaa
    29161 gacaaggata atcgctgcaa ttcctgctaa aaatgaatag atttttttca tgcttgctcc
    29221 tccttctcac gagagataaa gtaataacct acaactagga taatactaaa gagaaagact
    29281 agagcagaca gggcattgat ttctaaggaa atccccttgc gagcacgaga gtaaatctcg
    29341 actgataggg ttgaaaagcc atttcctgtt acaaagaagg tcacggcaaa atcatccagc
    29401 gaataggtga aggccatgaa gtaacctgca atgatagacg gagtcaggta aggaagcatg
    29461 atttccttaa acatctgaaa ttgactagct cccaagtcat aggccgcatg aatcatgtcg
    29521 ccattcattt ccttgagtcg aggcaagacc atcaagacca cgataggaat ggagaaggcc
    29581 acgtgactag atagaacggt caaaaagcca agtgaaaact tgagttgggt aaagagaatc
    29641 aagaagctag caccaatcat aacgtcaggc gcaaccatga ggatattatt gagtgataga
    29701 aaggcttctt ggtatttctt acgagactgg tagatgtaaa tggcaccaaa agtcccgata
    29761 atggtcgcta tcaaggctga taggaaggcc aagaaaaatg tctgagccaa aatcagcatg
    29821 agtctcccat ctccaaacat ggtttcaaag tgagtccagc taaaacctgt aaagctattc
    29881 atatcatcac cagcattaaa ggcatagcca atcaagtaaa aaatcggcag gtagaggacc
    29941 agaaagacca gtcccagata aaggttggca aattttttca tcgttctctc ctttccttgg
    30001 tcacccacat ggtgatgaac atggtcagga tgagaatcac accgatggtt gaacccatac
    30061 catagttgtc attggttaga aaattctgct caatagccgt ccccaaggtg ataacgcggt
    30121 tcccaccaat caaacgggtc agcatgaaga gactcaaact tgggataaag accgactgaa
    30181 ccccacttcg cacaccgttc atagatagag ggaagatgac atgacggaag gtctcccact
    30241 tagttgcacc aaggtcgtaa ctagcattga tgagattatt atccatatcg tctaagacat
    30301 tgaaaatcgg caaaatcata aaggggagct cgatgtagct tgcgacaaag ataaaggaaa
    30361 aatcggtaaa aagcaactgt tgtgaaccaa ttccgataaa ttccaagaat tggttaatag
    30421 agccattttg accaaaaatc ccgataaaag cataggcttt aaggagcaaa ttgatccagg
    30481 taggaaggat aatcagcatg agccagagtt gacggtgctt gagacgggtc aaaaagaggg
    30541 ctgttggata gctgataagc aaggtcacaa aggtcacaat ccctgcataa agcactgagt
    30601 tgaaactcat tttgaggtag gtcaagtttt gtgacgcaaa gtaagattta taattttcta
    30661 aactaaactg gccttcaatg ttgaaaaagg attgtccgaa aatcaagacc aagggtgcca
    30721 atacaaagag ggcaatccaa agcatgtagg gcactacaaa gagtttagag cttgttttct
    30781 tcatctcttt cctcctcgat cgcattgatc agacctgctt cttgctcttc gatttccacg
    30841 tattcttcga tacgagcatc gaactcttct tcggtttcat tgagacgcat gatgtggatg
    30901 tcttctgatt caaagtccag accgatttcc tcacccacga tggccttacg ggttgagtgg
    30961 atcatccatt catttccaag ttcgtcatag gcgataattt cataatgaac tccacggaag
    31021 agctgggtgt cgaccttaac ttggagtttg ccttcttcag gaagggtaat gcgcaagtcc
    31081 tctggacgaa taacgacctc aacaggttca tttggcttca tcccaccatc aaccgcttca
    31141 aagcgtttgc cgttaaattc gaccaagtag tcctcaatca tggtacctgg caagatgttt
    31201 gactccccga taaaggtggc aacaaagtgg ttgattggct catcgtagat gtccacaggg
    31261 gttccagact ggacaatctc gccatcattc ataacgaaaa tccagtcact catggcaaga
    31321 gcttcttcct gatcgtgagt gacaaagaca aaggtaatgc ccaatcgttg ttgtaattca
    31381 cgcaattcgt actgcatgtc tgttctcaat ttcaagtcca gcgctgataa aggctcgtcc
    31441 aacaagacca cacggggttg gttgatgata gcacgggcga tggccacacg ctgacgttgt
    31501 cctccagaaa gtttgcggat ggaacgtttt tcataacctt ccaactgaac catcttgaga
    31561 acttccgcta cacgctgctc gatttctttc ttatcaattt tacgcaagcg aagtggaaag
    31621 gcaacatttt caaacacatt catatgtggg aacaaggcat aggattggaa gacggtatgt
    31681 acgtcgcgct tgttggttgg aatatcattg atacgaacac cgtctagcat gatatctcct
    31741 gtcgtcgcat ccagtaaacc tgcaataatg tttaggatag ttgatttccc cgaaccagat
    31801 gcacctagaa gggtgtagaa tttcccttct tccaactcaa agttgatgtc tttgagaacc
    31861 ttggtgttgc tgtcttcaaa aactttagag acgtttttga attcgataat tggttttttc
    31921 aattggcata aattccttct ttttcataga ttaaccgatc ggggctctgt caggtcccca
    31981 ctacctcttg cagggagtaa aaccacctgc atacatcttc gctaccgata ggctttcacc
    32041 ccctttccat gacatagcag cagcttttca aatacagctt cctacttgct ttcacccaag
    32101 atccggactt ctctttcaag cgtaatacct gagtgttcct tgactttttc gataaccgat
    32161 tggatcaagt cctcgtagtc tttggccgtt ccatctgcga cattgatcat aaatcctgca
    32221 tgcttttctg acacttctac gccaccgata cgatagcctt tcaagccagc ttctgaaatt
    32281 aactgacctg caaaatgccc gactggacgc ttaaagaccg agccacaaga tgggtattcc
    32341 aaaggttgct tgagttcacg taggtgcgtc aagcggtcca tttcctgctt gataacctga
    32401 tgggttcctg gggctagggc aaatttaact gacaagacaa ctgcaccaga ctcctgaata
    32461 gctgaatggc ggtaaccaaa agccaagtct ttagcagaca gggtttcgat ttctccatcc
    32521 ttggtcaaga ccttacaaga ctgcaagatg tgagcaatct cgccaccata ggcacccgca
    32581 ttcataaaga cagcaccgcc aacgcttcct ggaataccac aagcaaactc aaagccagtc
    32641 aaactatgac ggagggcaat gcgagttgtt tcaatcaagt tagccccagc ttctgcttca
    32701 atggtatagc catcaacaga aacgttattg agcttgtcac acaagatgac aaatccacga
    32761 atcccaccat cacgaacgat gatattgctt gcattgccaa gaaccatcca agggatattt
    32821 tcttggttgg caaatttcac aaggcgcgcc aactcaaaac gatttcgtgg aaagaccaaa
    32881 taatcagcct ctccacctac ttttgtataa ctatagctat gcaagggttc cttaaaacgg
    32941 atatcaattc cttctaagat ttcaagcatt ttttctctta cagacatgtc actcttcctt
    33001 ttacaaaatt cattccatta taccattttt agagacattt gacgaccata aaaatacctt
    33061 gtttggattt tgcataagaa aaagaggttc cccccttttt atgatttttt acaaaagatt
    33121 tccttggttc cataggcgac cagaacgagc tccagtgcta gaatcacttc aaccaagact
    33181 ggatttgtca accagcctac ttggaaaaga gatggtgcca gatcaaagaa ggcatgcaag
    33241 ccataggctg ctaggagata aatccatttc ttctggcgaa cagcttggta aacccaaact
    33301 gtcaaaagta attggaaacc aagcgccaag attcgctcaa aaccaagcaa ataaatctgc
    33361 cagaccgaaa gtgactgaat ggtttttaac atattttcag acagtaattg cataacctgt
    33421 ggattctgag tttgaactgc cgaaagaacg atgtaaagat tgagtaaact aataaggcct
    33481 agaaaaatca actccaagcc accatgccct aggccatagg ccaaggcatc tgccttttcc
    33541 aaacttctct ttttctccaa ccatttgaag aaaacaagac gagccgtttc ctcaaaaaat
    33601 gctgccatgg ctaggccata gataatatag ataagcggat gatcttgcaa gagggcaata
    33661 ctaccgtctt tttgaggatg caaaatcaag atatgcacca gtttttccaa aatctgcgaa
    33721 gagacaaaga aagcgactgc acccaagccc aagacagcta gattaatctg gtatttcttt
    33781 ttggtaaacc aaatgcttcc tatcagaaaa gctagcaaca gcaacatggt aataatgata
    33841 tgaatggtca ttttcttctc ctattctgcc ttttcaatat cttttttcat ctcgtcaaca
    33901 ttgaacttag caaacaagta ttgacggtct tggactggga aacgttggtc caactggtca
    33961 actgctccca cctcgataat gccttccttg atgacaaaat ccatgacatg tccaccgaag
    34021 gtcaaatcat ctgatatgaa gtgcagatgg tagcctgcca cactgacccc atggaaaatc
    34081 tgaggcgtcc agaaaccaac aatagtcccc gcaacattgt cacgactata ttccggttga
    34141 tgggttgcga tatcagcaaa cttagtatcg ggtgttgact taggaatcat acgcacatgc
    34201 atatgtgaaa attccccccg aatcttgata gagcggaaaa gattttcccc atcataataa
    34261 gactcaattc gttctttcaa ttccttgtct gtcatctcaa agcgctggcg gaaaatgacc
    34321 tctgcctgat gcggtaccac tgcagcgtaa ggaataaggg catctggtga cacttccaca
    34381 atttctggct ggtctcctga ctctttggcc tgataagcct tgccatccaa gacaatcaat
    34441 tccccatcaa tggaatccaa ggttcccaaa ccaaggtcac catgttctag caattctcct
    34501 actgtcatag taccaccata aaggccagcc atcaaggctc caagagtatt gtattgaaat
    34561 aatttcactg gttcctgcac gttcttatcc attcactttc ttgtctgtta ttctataaat
    34621 cttactccta agtataccac atttgcccct agatgtgaac gagagaaacg ctctagacat
    34681 tgccaagaag gaaaaaaaag ggtacaatgt aacaaaatca agggaggtct ggaatgaaga
    34741 aacaaagcaa gtacaaagag gtcgtttcct atctgaaaaa tggtatcgag tctggacgat
    34801 ttccgacggg tagtcgcctg ccttctatcc gtcaactgag ccttgacttt cactgcagca
    34861 aggacaccat tcaacgagcc ctgctggaat tacggcacga acaatacctc tatgccaagc
    34921 ctcagagtgg ctactatgta ttagaacaag ggcaacatca agacctagaa atcgaggtta
    34981 ccgacgaaca tgccagtgcc tatgacgatt tccgactctg tgtcaatgaa accttgattg
    35041 gccgagaaaa ctacctcttc aactactatg acaatcaaga aggattagaa gacctaagac
    35101 aatccattca caaactcctc tttgaccaag ctctctactg caaggctaac caactagtac
    35161 tgacttctgg aacccaacaa gccttgttta tcctctctca aatatccttt cctagccaag
    35221 ccaaggaaat cttggtggaa cagccaacct accatcggat gaatcgcctc ttgattgcac
    35281 aggggctgga ctatcaaacg attgaacgag gcattgatgg gattgacttg gaggagctgg
    35341 aaggccactt caaaacagga aaaattaagt ttttctacac cattcctcga tttcactatc
    35401 ccctaggcca ttcctattct gagcaggaca aacgagctat tcttgactta gcagccaaat
    35461 atagtgttta tatcgtcgaa gacgactatc tgggggattt ggactctaaa aagggccaga
    35521 ccttccacta tctagataca gaggaacgcg tcatttatat caaatccttc tcaaccagcc
    35581 tctttccagc cttgcggata acagcactca ttcttccaaa tactatcaaa gaagccttcg
    35641 tggcctacaa aaatatccta gactacgaca gcaacctcat catgcaaaag gccctgtcac
    35701 tctatattga cagtcaattg tttgaaaaaa atcgtttggc tcgcttgacc aatcatgaat
    35761 cttaccaaaa acaaatcgag gaaaggataa ctaaaacacc ttgtcccctt cctcattatc
    35821 ccctacacga tggtttattg ctagacctga gacagtatcc taaaatcgcc agtctcaaac
    35881 acagtcaact gggcttggac ttctttgaag aggcctattt aagcacctgt ccttatcaat
    35941 ttgccaaggt gtccctagac aatctggaaa atgttttaaa ctatttaaaa gcagaattgg
    36001 aatgacatcc aactctgctt tttcttattc ttcaacttca gttaaacttg ctgctttttc
    36061 aagatagctt tggtaagttc cttcatcctt aagtttttgg atgaccttgt ctaccacttc
    36121 tttcaaatca tcactatttt ttctaagagc aacgacattg gcgtcgccgt ccttcatctt
    36181 caagctgaca gttgcgacag ctaagccagc gtttttagca gcataactaa gtgcaacagg
    36241 ctcatccata tgaacagcat ctatttttcc agcctgcaat tcattgactg cttcacccat
    36301 attagttagg gaagttaatt gagcttttgg caattgttcc ttgaccattg attctggaac
    36361 agtccctttt tgggctgcaa tattagcact ttctaggcta gttaaatcct tgtatttttc
    36421 cacatcagcc ttacgaacca agaaactaat cttgttttca tagtatggga ttgaaaaatc
    36481 aaagacttct tttctctcgt cagtagcact aattcctgca actgctaggt cagccttacc
    36541 agtttgaaga ctggtcaaaa cattgtcaaa actcatgctt aagatttcca acttaacccc
    36601 aagttcatca gcgatagcct gagccatgtc gatgtctgca ccgactacct ggttctttcc
    36661 atcaaccaat gattgaaatt caaagggtgc atagtcagga ctggttgcca caactaattt
    36721 ccccttttgc ttaatggcct caacagctga ctgagaacca ttagaacctg actggcaagc
    36781 tactaagaag aaacttgcaa gaaacttgca agaaaattac ataaaacaaa tatccatttt
    36841 tttgatttca taaataaaca acctttctgt taattttgta taattataac gatatccaag
    36901 ttacttgtca agtgtttttt aaatttttat ctcaaaaata ttttttcgtt caaaaaaagg
    36961 agccatcagt tgatttcaag ctccttttta tacagaatta aactatttta tagttcgaca
    37021 atcttacctg tttcaaagta gacaacccat tcacagatat ttttagcata atcaccgata
    37081 cgctccaagt aggaaataac ttggaaataa tcacgacccg taacaatggc ttctggattt
    37141 ttcttaatct cttcagtcgc aaggtcacgg atagtttcaa aatagtggtt aatttgctca
    37201 tccatggagg ccacccggta tgcgtcgtca acagaaccat taagataaag atcaagtgct
    37261 gcttcaacaa cgcttttaac ttcacgtccc atttttttaa tttcttcctc tacagctggg
    37321 atgcgttctt cccccttcat acggatggtt gcctgggcaa tggctacagc gtgatccccc
    37381 atacgctcca catctgatac agccttaagg acagtcaaga ctgtacgcaa atcttgagag
    37441 actggttgtt ggagtgcgat catttcaaat gatttctttt ccagtttcac ttcgtattca
    37501 tttacttctg catcatcttc tatgacctct tttgccaggt cacggtcatg cgtgacaaaa
    37561 gcacgtaccg tacgattgat ttgtgagagc acttcttgtc ccatagcgta gaactggtta
    37621 tgtaatttct ctaaatcttc ttcaaattga gatcgtaaca tctttcatct ccttatccaa
    37681 attttcctgt aatatagtct tccgtttcct tgtgttgggg atcaaggaac atctgcttgg
    37741 tatcattaaa ttcaatcaaa tctccatcta ggaaaaatcc tgtcttatca gagatacgtg
    37801 aagcttgctg catggaacgg gttaccagaa gcatggtgta cttgtctttt agaccataca
    37861 aggtttcctc aattttacca gctgaaatcg gatccaaagc cgaagttggc tcatccaaga
    37921 ggatgatttt aggactagtt gccaagacac gggccacgca gacacgctgc tgttgaccac
    37981 ctgacaatcc aatagctgaa tcatatagac gatccttgac ctcatcccag atagaggcac
    38041 cttgcaaggc tttttctacg gcttcatcca gaacctgctt atccttaatt ccattgatac
    38101 gaagcccgta gacaacattc tcatagatag tcatagggaa aggattaggt tgttggaaaa
    38161 ccattccgat ttccttacgt aattcaaccg tatctgtacg cggactgtag atgttgtgac
    38221 cattgtacac cacggatcca gttgtggtca cctctggatt gagatctccc atgcggttga
    38281 gagacttgag gagggttgac ttccctgatc cagatggacc aatcaaggct gtaatttcct
    38341 taggttggaa agatagggaa acactattca aagccttctt tttattataa taaacggaca
    38401 ggtctgatac ctgtaaaatc gcatctgtca tacggtttcc tttctaacca aagtgaccag
    38461 atacatagtc attggtggac tgtagcttgg cattttggaa aatagttgca gtcttatcat
    38521 actcaatcaa atcacccaag taaaagaagc ctgtatagtc acttgcacga gcagcctgct
    38581 gcatattatg cgttacaatg atgatggtaa agtttttctt gagctcaaac atggtctctt
    38641 ctagttgcat ggtcgcaatc ggatccaagg ctgaggctgg ctcatccatt aagaggatat
    38701 ctggcttaac agagatggca cgagcgatac agagacgttg ttgctgacca cctgataagg
    38761 tcaaggctga cttgtggaga tcgtctttaa cctgatccca gagggcagcc tgacgaaggg
    38821 aggtttctac gatttcatct aggacttgct tatccttaac tccagcacgt tcatgcgcaa
    38881 aggtgatatt acggtaaatt gacttagcaa atggattggg gcgttgaaaa accattccaa
    38941 tgtgtttacg catttcataa acgttgattt ctggacggtt gacatcaatt ccacgataga
    39001 gaatctgccc agttacttta gcaatatcaa tagtatcatt catgcgattg agactgcgta
    39061 agtaggtaga tttccccgac cccgacggac caatcaaagc tgtaatttta tttctttcaa
    39121 attgcatatc aatcccctta atggattcat ttttaccata gtaaacatgg acatccttag
    39181 tagaaagggc tactttttct tcaggaaagg taaggatatg cttctcatcc cagttatatg
    39241 ttgacatggc ttctccttta ggcagcggtt aatttcttgt gtagatagct tccgaactta
    39301 cgagctccaa agttaaaaat caggataaag atcaggagca cagcggcaga acctgctgat
    39361 acaatggttc catctggaat agtgccttca ctattgactt tccagatatg gacagccaag
    39421 gtttctgctt gacggaagat agagatgggg ctagtcacac tgaggatatt ccagttagac
    39481 cagtcaagag ctggcgccga ttgccctgct gtatagatca gagctgcagc ttcgccaaag
    39541 atacgaccag atgccaagac gacacccgtt acaatacctg gaagcgcttc tggaataaca
    39601 acatgaacca ctgtctccca gcgagaaatc ccaagagcca gaccagcctc acgttgggta
    39661 tggtgaacgt gtttcaaact atcctctaca ttacgcgtca tctgaggcaa attaaagact
    39721 gtcaaggcca aggcacctga aatgattgaa aatccatact caaactggac tacaaagatc
    39781 aagtaaccaa agagacccac caccactgat ggtaaagagg acaagatttc aatacaagtc
    39841 cgcacaaagt tggtaacagg acctttttta gcatattcag ccaagtaaat cccagctccc
    39901 atagaaagag gtacagaaat aatcaaggta atgaccaata ggaaaaagga attgtaaagc
    39961 tgaatgccaa tcccaccacc tgcttgaaaa gcagaagacc ttccagtcaa gaaagaccaa
    40021 gagatatggg gcaagccccg aaccaagata tagagaatca aggaagccaa gattgtcaca
    40081 atgatgctag caatcgtata gaggacagct gttgcaagtt tatctaattt cttagcgcgc
    40141 ataatttttc tttcctcttt ctttcgtaat caatttaatc acactgttaa aaactaaact
    40201 catcaagagc agtaccaagg ccagtgacca gagaacatta ttatttacag ttcccatgac
    40261 agtgttccca attcccatag ttaatataga agttaaagtt gcagctggtg tggtcaagga
    40321 agttgggata acagctgagt ttccgacaac catctggata gctaaagcct caccaaaggc
    40381 acgcgccatc ccaaagacca ctgcagtgaa aataccagaa cgggccgcct tcaagatcac
    40441 acgccagata gtctgccagc gagtggctcc catagcgaaa cttgcctcac gataataacg
    40501 aggaaccgca cgcaagctat ccgttgtcat aaaggttacg gtcggcaaaa tcatgacaaa
    40561 gaggacggaa atccctgaca aaatcccaaa accagtccca ccaaagacac tgcgaacaaa
    40621 gggaacgacg acttgcaagc caataaatcc gtacactact gaaggaatcc caaccaggag
    40681 ttcaatagct ggttgcaaaa tcttcgcccc ttttggtgat acttcggtca taaaaactgc
    40741 tgcaccaata gcaaagggtg ttgcgataag ggctgagaga atggtaacga taaaggaacc
    40801 caaaatcata ggaagggcac caaattcttt actagaagga ttccaagttc ctcccaaaag
    40861 aaagtcaaag atattcacac cattgacaaa gaaggtcgac aagccttttt gcgctacgaa
    40921 aaccaaaatc atggccacaa ggatgactat caaagaaaga caggcaaagg tcaaaccttt
    40981 tcctaatttc tccagacgag aattctttga tggaagcaac attttcttag ctaattcttc
    41041 ttgattcatt attgtctccc ttccaacact gtcacagttc cggcagcatc tttttcaacc
    41101 ttcatttcct taatcggaat atacttcaat cctttgacaa tcccttcttg ggtctcatcc
    41161 gagagaacaa aattgagaaa ttctgcagct aactcattgg gctgccccaa tgtatacata
    41221 tgctcataag accacaaggg ccaattattg ctacttatat tttctggact taagtcatag
    41281 ccattcaact tcatgctttt gaccgaatca tctatatagg taagagataa ataagagata
    41341 gctcctggac tttttgatac gattgatttt accgctccat ttgaatcctg ctcctgactt
    41401 tgcatggcag actgaccttc cataatgaca gtatcaaagg tagcacgaga gccagagccg
    41461 gctgcccgat tgataacaga gatgggtaag tccttaccac caacctcttt ccaattggtt
    41521 acctcaccta tgaagatttg acgaagttgc tctgtcgtta gattatcaac atcaacctcc
    41581 ttattgacaa tcagagccaa gccagctacc gcgaccttgt ggtcaacaag agcagaagca
    41641 tcaattccgt ctttttcctc agcaaataca tctgagtttc ctatatcaac tgccccagac
    41701 tgaacctggg acaagcctgt accagaacct cccccttgga cattgaccgt ttttccaaca
    41761 tggatcgtgc caaattcatc tgccgctact tcaaccaagg gttgcaaggc agttgagcca
    41821 acagccgtta tggattctcc acgatcaatc cagctagcac agcctactaa acaagccgtc
    41881 agccaaaaag cgataagaga cagagcaagc ttttttcttt ttttcactgt ttttctcctc
    41941 gaaaataatt atgaatactg tgaatttttt aagtagttct ttatgagttg acgcatgaat
    42001 tcttaccaaa tttctgcgca attgattatt tatataatat aggctatatt actctttcct
    42061 aacctccttt tttcatatgt ggataaaatc tcttgtctat cccttccccc attgtcaccc
    42121 attatagtca tttcgtgtct ctttttcccc tttttaatgc aagggaaatt actctcctta
    42181 gatgataatc taaaagctag aaaggtatct caaatctctc tactctccca gactagttta
    42241 caactaaaag gaaaagattc tattttatga gaaatctagt ttacaagcgg taagaacgct
    42301 aataactaaa cttcttgtac tctttgaaaa tctcttcaaa gcagtgtttt gagctatcta
    42361 tggctagctt cctagtttgc tctttgattt tcatcgagta gtaaaactac atgtgatggc
    42421 aatcaagata tcaagaatca tcctactaaa aaaatccata ctttcactat aacatagaat
    42481 aagatatttg actagcattt tcatttgaat ctgaggcctt ttggaaaata atttttcaaa
    42541 acatttccag taacctttgc aaagcccaag ccattgcctt taaccaaaac ttggtaccaa
    42601 ccatttggca gactttctgc cagctgaacg gtttctccag ccgcatactt gacaaactct
    42661 tcttggccaa tttcaaccga ctgttcgacc tgactcggtt tcaaggctaa accaagagcg
    42721 aaactgggct caaagcgttt cttcttaaaa gtacccagat gcagtccatt gcgagcaatc
    42781 ttgagcttcc ctaaatctgg caaaagttct ggcaagagat aaagctggtc tccaaaaatc
    42841 tgcaagatac ccggtagatt gaccttcaaa tggttttggg caaattcctg ccacaaggca
    42901 acttgttcac ggctgaggtt actcttactt gccttaaatt taggagctgg attgttaccc
    42961 ttaaactgta gatgggcaac aaactgaccc tctcccttaa actgatgagg gtacatccga
    43021 gccgtttctg gcaggtcaat accagctacc attccattga tatgctctac tggcaacaag
    43081 tcaaaatcat actcttccag caaccaattg acaatctctt cgttttcctc gggtgcccag
    43141 gtacaggtcg aataaaccag acgaccacct tcagctaaca tggtcactgc atcctccaga
    43201 atttctcttt gcaagctagc acattgactc ggataatcta agctccaata gtccatagca
    43261 tcaggttgct tacgaaacat tccttcacca gagcaagggg catcaagaac gattaagtca
    43321 aaatagcctt taaagacctt gaccaagcgg tcggcagatt cattggtcac cacgacattt
    43381 gtcgctccaa aacgctccat gttttcaacc aaaatcttag cccgtttgct tgaaatttca
    43441 ttggaaacaa gtagcccctc ccctgctaga taggctgcca gttgagttga tttgcccccc
    43501 ggtgcagcag ccaagtccaa gaccttcata ccaggactgg gttgggctac ttgagccacc
    43561 atttgagcag caggttcttg cgaataaact aaacctgtag catgctcagg cgatttccct
    43621 gaaaccttcc catagtggcc ccaaggggtt tgagtaatgg catcagaaaa ggaaagttgc
    43681 tcttctttta agggattgac ccgaaaggcc gaaaccgctt cctcctcaaa agaggcaaga
    43741 aaatctcttg cctcatctcc tagtatttct ttatattttt caacaaatcc ttctggaaat
    43801 ttcatttaag ttcttttcct ttcgtaaata taggactgaa tttcctcctg catctcaaga
    43861 ggcaccatca tgaccggctg tctggtttga aaatcaggag cttcaccaaa aagggtcaca
    43921 acccgatagc ccagactttc ccctaaaata ctagctgcgg cataatccca tggttgcaga
    43981 taggtgagat aggtcaacaa acgccctgac aaaatcttgg caaaactaat ggccgcactt
    44041 ccatagacac gaacaccaag aaccgctcgg ctcaaatcag ccagccccca ttcattggtt
    44101 tccagcatac cactattccc tgcaatgaga aaatctccaa gtggtttagt tttaaaagaa
    44161 gctaggggcc tatcatttag acaaactgga aattccccac caccgtggta acaatcccct
    44221 ttgaccacat cataaatcag accaaactgt ccctgaccat tttcaaaata agccatcata
    44281 acagcaaaat cttcctgctg ggctacaaaa ttattggtac catcaatggg atcaatgacc
    44341 caaaccttgc cctcttgaac cgaggctcgc agacaacctt cttcagcaca aatcttatcc
    44401 tcaggataac gggacaaaat ctcaccaacc aagagttcct gaacttcttt gtccagtctg
    44461 gtcaccaaat ctgttggaga ggacttggtt tcaacacgca agtcttcctg catatggtca
    44521 agaatgtact gacctgcttt cttaacaagc tctttagcaa attcaaattt actttccaag
    44581 agaaatcttt ccttcccctt tttctttggc agcctgaact gctcggtaaa gtgaatagcc
    44641 actaaccgtt tcaaattctc gtcccaaacg tttctcttcg ctcttgcttg gcacgaccgc
    44701 tttgaatccc ttataggagt ccagtaactt tttagcctct actttgcctt cataggcagc
    44761 ttcaacatca ttaaaaaaag aaagcactga agcaagttct tcagtgctcc acgacaaatc
    44821 tagtgggtaa ctatactgtt tgttcattaa ctaataccag ctctcattct tgcttctttt
    44881 agttcttgct tacgataact acgagggaga aaagcacgaa tctcatcttc attaaaaccg
    44941 atttgcatac gcttggcatc aataataatt ggacgacgca aaagactagg atactgctca
    45001 atcaaatgaa gcaattccga taccgaaata ctctctacat caatattcaa tttttgaaaa
    45061 atttttgaac gagttgaaat gatgtcatca gtaccatttt cggtcaagga aaggatttgt
    45121 tgcaattctt ttcttgttaa aggactggtc ataatattgt gttccacaaa gggaacctta
    45181 tgtttttcta accaggcctt agccttacga catgatgtac agctcggtga tagaaatagt
    45241 gtaatcatgc ttttctcttc ttatctatac tttgctactt ctattataca aaaaaataag
    45301 gcgcttgact agggattttt agaaaaaaag cctatttttc aagaaaaata ggctgtttgc
    45361 gaacgattga cacaattgga tttggttaat tcactcttaa cgatggtttt aaacgatata
    45421 tatttttata tatgcaaatt aaaaacatct ttcatttcat ttcctacgac ttttcagaca
    45481 cagatagcca aagaagcttt catagagggc aaaaaagagg aggaaggcat gaagaaagaa
    45541 ggtctctggc aaaatcataa taacaggatc cttggctgga tcaaaaagcc aggtatcatc
    45601 tcccacaaag agaatttgat ggaaaagagt aaagaattgg tcaaaaccaa tcaaaactcc
    45661 cccaagtcca atcatcacag gtaagactac tagagtcagg agactttttc gataaagaga
    45721 caaaaagtcc tttttcacaa ttctattgac aaagacatag aaacttggca gtgtcactag
    45781 agctactagc tgaaccaaat gaaagagatt cttgaccact gcgaaatggt gcagaccagc
    45841 tgctgacgaa cgaaaatcag gcatctgtaa gacctgacta aaaggattgg tcagataatt
    45901 catcaagata tgaaaattgt attgaatggt ttctggtttt agatagactc gattcgttaa
    45961 gtttagccac tgaatctcca taggatagaa aatccaagcc agataaatgg tcagaaggat
    46021 tgagagggag aggagaaaga gcatagagcc ccaaaagatc aatttagttt tcatcaaaat
    46081 cccactccgc aaggctagaa accacatgtg tcggtgcgat tggcaggcca gctacttctt
    46141 ctgccttagt aaaacctgtc gtcaccaaga gcgttggaat gccattgtca atcccagccc
    46201 ggatatcagt caaataattg tccccaacca taattaactc ttcacgttcc aaacctaagt
    46261 gctcaaccgc cttgtccata atgatggcat tgggttttcc gatataaacc ggcttcactc
    46321 gtgtcgctac ttcaagcagc gtaatcaggg agccagcacc tggcaaaaga ccacgttccg
    46381 tcgggatgtt gaggtcagga ttggttccga taaaatgggc acccttttga atagcaagag
    46441 ttgctgtggc aaatttttca tagtcgactt gccaatccag accaactacc acgtaggcag
    46501 ggttttcctt gtcttccaca taaccagccg ccttgatggc ttccttgagt cctgcttctc
    46561 cgacgacata gacggtcttt tcaagcccca aatcattcat atagtcgatg gttgccaaag
    46621 tcgctgtgta gacagtcgat aggggcgtat cgatattaaa attctgagcc aacatctcct
    46681 taacactctc tggagtgcga gttgtattgt tggttacaaa gagataggga atgtcccgct
    46741 tttgcaattc atgaacaaaa gtctctccag cagggattcg gtctttcccc ttataaatgg
    46801 ttccgtctaa atcaattaaa tagcctttat atttcatcta tttctcccta agcctttttt
    46861 atttctttcc aagtaatgat tgcttgggca ttgataaccc catcacttgt aatttcatgc
    46921 ttgctttcca gtccagtccg ttcaacagcc gatgtaatca ccccacctgg tcgaacttcc
    46981 ttgacatact tgaggttgat tttcttggga atatagtggg tcaaaaaatc cgctcccatg
    47041 acctcaaaaa tccagtccaa gtatttactg ttattgacat gaccattcat atccaagtcg
    47101 taaaaacgaa catggtaatc cttgctgatc ggctcttcca aggactcata cttcggtcca
    47161 cggataagtt ttttatcaaa atcagactgg taaggagcca caatctcagg ttcaacagca
    47221 tggacttttc gactgtcgcg gtccatgaga acaaaggtcg ccatcatatg gatgagctcc
    47281 tgccccgctt cattataaat agtaaagcga cggtagcaaa aaagtcgatt gtagctcaag
    47341 gcttccgttt cgatggtaat ttcttccgca aaacgaggca aacgaaccac ctcaatatca
    47401 tattctgcga taatccagac cagattatag tcttccaaaa tggccttatc actaactccc
    47461 agttcaatcg actgcatccc tgaaacttgc agtgacagca aaatcacatc tggaagtttg
    47521 atatgaccgt tcatatcagc catatcaaaa ggaattttca ttttcatttg ataagttaag
    47581 cccatgatcc tactccaaaa taaatcgttc tgctacagta tctcccaaaa agagacctct
    47641 ctttgtcatg cgaacgtggt caccctcaat ctgcatgagg ccttgttgaa ccaaatctct
    47701 gacaatttct ccataaagtc cagcaaaaga ctgtccaaat ttttcctcaa atcgcgccat
    47761 ggaaaccccg gatttcttgc ggagtcccaa gaacatttct tcttccattt gctccttttg
    47821 actcaggtga tcttctgtaa tacaagcatt gccttcctca accgcactga gataatgacg
    47881 aatgggacca tgatttttat aacgtactcc attgacataa ccagatgccc ctgcaccaat
    47941 accatagtat tcagcattgt cccagtacat gagattgtga cgactttcaa agccgggttt
    48001 ggagaaatta gaaatctcat aatgctcaaa acctgctcgc tccagctctg caatgatgta
    48061 ctcaaacatc tccgcttcta gttcctcctt aggcagaggc aatttcccac gtcgcatccg
    48121 gttcataaag accgtatggt tttctaaaat caaactatac aaactcatgt ggggaatatc
    48181 cagtccaatg gctttagcca cattttcctt tacttgctcc atggtctgac caggcagagc
    48241 ataaatcaaa tcaatggaga tattgtcaaa accagccagt ttcaggcgat cgatattttc
    48301 ataaatatcc ttctccaaat gactgcgccc aatttttttc aacatcttat catcaaaggt
    48361 ctgaacacct agcgaaacac gattgacagc cgaatttttc aaaacagcta tcttatccgc
    48421 atccaaatcg cctggattgg cttcaatggt caactcttcc aagacagaca agttcaagtt
    48481 tttagtcaag ccattcagta acacctccag ttgcggagcc gacagggctg tcggtgttcc
    48541 accaccgata taaagggttg acaacttttc aatatcataa gaacgaaact cttccagcag
    48601 atgctctaaa tagctgtcga ctggctgatt tttgatgaag acctttgaaa aatcacaata
    48661 ataacaaatc tgggtacaaa atgggatgtg cacataggct gacgttggtt ttttctgcat
    48721 agtaattatt ataccacaaa gactagattc cagataaaaa tcaccatccc cagatacata
    48781 gtccgtccgg agatggtgat ggtttattct tctgttatat caatcacaat ctcttctgag
    48841 tcatcaagag cttcggcttt ttcttgccat tgctccttga gattatttaa ttgatttttt
    48901 gatgcttctg tcgcttgaaa agcataggat ttagcttgag caagtatact gtccacagtg
    48961 atttcacctg actcaacctg ttcttttgtt ttcagaacaa aatctgtagc ctgctcctta
    49021 acttctgtca gtttttcaca gacttgctcc ttggcatact ccggatcttc tctcaaatca
    49081 tctagaaaat cttgagcctg actgcaaact tgtttgccct tatcacttgt taaaaacaag
    49141 gcaagagctg cacctgaaac cgttcctaaa aggattgagg ataatttacc cataaggatt
    49201 ctcctttttt attttttgaa aaatttactt gcaagacgaa gagctgacag acttgcacca
    49261 gtcttgagtg tttttgaacc agctgatgaa gctttcttgc tcaagacacg cgcatggtca
    49321 ttgaggtctg aaacagatag agataaatct gcaacagcac tgaagagtgg atcaatcgta
    49381 gccaccttga cattgatatc atctgccaag acattgacct tagccaacaa ctcattggta
    49441 tgatgcaagg tcacatccac atctgaagtc aaggttttaa tcgtcttttc tgtttcatcg
    49501 atgacacgac caagcttttg tacagtaatg atcagataga ccaaaaagac aatcaaagct
    49561 agggcaacaa gaatatatgc aacttctaac atttagtttt cctcctctgt aatatagtaa
    49621 ggggccttct ttcgattttg ataaataacg atcattatac cgagaccgat aaggacaact
    49681 gacagccatt gggacactcg aaggccgaag aacatgagac tatctgttcg cataccttcg
    49741 atgaccatac gaccgaaacc ataccaaatc aagtaaaagg ccgtgatatg acctcgtctg
    49801 agactcttcc atttccgtct aaaaatcaga atcaaggcaa agccaagcag attccataga
    49861 gactcataaa ggaaagtcgg ttgacggtag ctcccctcaa tatacatctg gtcacggata
    49921 aagccaggta gataatcaag attatccact gttgcaccat aagcttcttg gttaaagaaa
    49981 ttaccccaac gccccaaact ttgagcaatc ataacgctag gcgccgcaat atctagaaaa
    50041 tcccaagtat tgatgagttt acggtcagca aagatataga gcacaagagc cccagttatc
    50101 aaaccaccgt aaatggccaa accaccattc caaatggcaa aaatctctcc taaattctga
    50161 ctatagtaat caaatcggaa aataacatag tagagacgag ctcctaaaat agccaaggga
    50221 aaggctacta agataaaatc taaaatatcg tctggtatga tcttctttct aggtgcttct
    50281 ttcatggtca aataaaccgc aagaatcaag cctgtcacaa tacataaggc ataccaacga
    50341 atggctaggg gtcctagttg aatagcaatt ggatcaagca ttttgcacct catttcgagc
    50401 gattagactt gtcagtcgtt cgtcgaacaa acgggtcgca tcaaagccca tttccttggc
    50461 acgataattc atggcagctg cctcaatcac aacagagata ttacgacctg ttttaactgg
    50521 aatacgaata cgaggaatgg ctacgccaga aacttcaagt tcctctgcat tgtttccaag
    50581 acgatcaaag gtcttatgtg tatcgtaatt ttccaaatag acagcaagct gaacctgtga
    50641 agaatccttg acagcactcg caccgtagag actcataaca tcgataatac caaccccacg
    50701 aatttcaatc aagtgtttca aaatttcagc tggttcaccc cagagagtaa tctcatcctt
    50761 ggcaaagata tcgacacggt catcggctac caaacggtga ccacgtttga caagctcaag
    50821 acctgtctcg ctcttaccaa ttccactatc tccctgaatc aagacgccca tcccataaat
    50881 atccatcaag acaccgtgca cactggtacg ttctgccaaa cgagaatcca gatagctaga
    50941 taactctcca gataaacgac tggtagctgc acggctggtt aaaatagcaa tcttacattc
    51001 tctagcagcc tttaacatct cctctggaac caccaaacca cgggcaacaa tgactgctgg
    51061 tgtctcaggt agaaacattt ttttcaaaac ttcataacgg ctgttggaag gcatgctgat
    51121 cagataagac cactccttca tccccaaaag ttgaatccgc tctggtgtat agtagtcaaa
    51181 atagcctgtc atttcaagac caggtcgcgt aatatccgct atattgattt ccttttcaag
    51241 caattctggt tcaccataga caatgtctag tctaagcttt tcaatcactt cttttactaa
    51301 aaccgacatc atttcctcct tcaaatgagt tcttctctct attatatcaa attgtaggag
    51361 gaagtttcag atttttgcag gctttggagt atttatttaa aagaaaaagg actagatttc
    51421 tctagccttt cattccaatt agaatttttt acgtttacga gctacttctg atttacgttt
    51481 acgttttaca gaaggttttt catagaattc acgtttgcgt gtttcttgaa gagtaccagc
    51541 tttagtaacc gcacgtttga aacggcgaag tgcgtcgtca agagattcat tcttacgtac
    51601 tactgtttta gacatttttt tcactccctt caagttcaat atctatttca ttctacacgt
    51661 aaaaggaata attgtcaagc aaaaatgcgg tttaattttg attttttctt ccatttatac
    51721 aagagttgaa agcgttcaat agaacattgc ttttttattt ttcgagtaag ctaagcgctt
    51781 cagcatctgc gatgatggtt acatcagggt gattttggag gctacttgca ggtaggttct
    51841 cagtcactgg gccagatact gttccggcaa tggcttctgc tttcgactca ccgtaagcaa
    51901 aaagaataat agacttggca tccaaaatgt ttttaatccc cattgaaata gcttgggttg
    51961 ggacgtcttc aatcttggca aagaagcgtg cattggcttc aatagtagac tggtcaagtt
    52021 ctactagatg cgtttgactg tcaaatggag taccaggctc attaaagccg atatgcccat
    52081 tgcgaccaat tcccaagatt tggaggtcaa ctggatggtc agccaaaatt tggttgtagc
    52141 gttcaacttc agcttcagca ttgtccttaa caccacgagg caagaaactt tctttaaatg
    52201 gtttttggtt gaacaagttt tcttgcatga agtaacgata agactgtgga ttgtccccat
    52261 caaggcccac atactcatca aggttgacac tggttagatt tgaaaaatca aggtcactct
    52321 caacaatttc cttgtaaaat tcaagtgggc tacttcctgt cgcaagtcct agagtttgag
    52381 ctccattagc caatttttcc ttcaaaatct caaaagcaac ttttccacct tgaacttggt
    52441 tttcaacttt aataactttc atcttttcat cctccatttc tgtctatatt tattatatgg
    52501 tatagaccaa tttttgtcaa gtgaaaacga tttaatttct aaaaaaagag cgtccaaact
    52561 tgaaacgtgt tataatggat aggattataa cttagaaaga atgaacaaat atatgaatac
    52621 agctgatttt gatttccact tgccagagga attgattgcc caaacgcccc ttgaaaaacg
    52681 tgatgcctcc aaactcctca tcgtcaaccg tgagacagga gaaatgcaag ataaacattt
    52741 ccactctatt attgatatgc tggaacctgg tgatgccctt gtcatgaacg acacccgagt
    52801 tctccctgcc cgcctctatg gtcaaaaaat ggagacagga ggtcatgtgg aacttctcct
    52861 ccttaagaac actagtggag acgagtggga agttctggct aaacctgcca aacgcctcaa
    52921 ggtcggtact cgtatcagct ttggtgatgg ccgcctcagc gctgtcgtta cagaagaatt
    52981 gacccacggg ggacgcattg tccgctttga ataccaagga attttcctag aagtcttgga
    53041 aagtctggga gaaatgcctc tgccacctta tatccacgaa aaattagatg accgtgaacg
    53101 ttatcaaacc gtctacgcca aggaaagcgg ctctgctgca gcaccgactg ctggtcttca
    53161 cttcaccaaa gaactgctgg cagaaatcca agctaagggt gttcatctag tctatctgac
    53221 tctccatgtc ggactcggaa cctttagacc tgtttctgtg gataatctgg acgaacacga
    53281 aatgcactca gagttctatc aactttctga ggaagctgct gccacccttc gctctgtcaa
    53341 agaaaatggt ggtcgcgtca tcgctgtcgg aaccacttct atccgcacct tggaaactat
    53401 tggttccaag tttgatgggc aaatccaagc agattctggt tggaccaata tctttatcaa
    53461 acctgggtat gagtggaagg tcgtggatgc cttctcaacc aacttccatc tgccaaaatc
    53521 aactctggtc atgttggttt ctgcctttgc aggccgtgaa ttagtcttag atgcctacca
    53581 ccatgccatc caagaacact accgcttctt cagttttggt gacgccatgt ttatttattg
    53641 agaaagaatt tctctaattc ttctaatacc aataaatcgc taagatatta tttcaaagaa
    53701 catctacaat tgaaactcta gctagctgta gaagacgcct agtacattga aattaaaatg
    53761 cttcccccta gcttcgaaaa tattgccata gattgcgttg actctccaaa ttgattcatc
    53821 tatattttat ttcagcttcc tatattttct tcgctgtttg taaatcaaaa tgcaagacac
    53881 atgagtagca ccatatttgt tactcttatc tgtcctctca agagactatt atgagttatt
    53941 tcagaatcat tcactacttt gaccctgact ctccttagtc tcaaaatcaa agacttatac
    54001 tcttcaaaaa tctcttcaaa ccgcgtcaac gtcaccttgg attatatatg tgactgactt
    54061 cgtcagttct atctacaacc tcaaagcagt actttgagca acctgcgact agttttctag
    54121 tttgctcttt gattttcatt gagtattaaa caaaaagtga acaaatctga attctaatgt
    54181 acagaagact aggcttgttc acttttttat agtcgctata agatgacctt atctatagct
    54241 ttttatatat aattatatat tcagacatac tattatcaat tttatcgcag ggaggaatct
    54301 gttaacgcac ccattcacca ttatcattga ctctatagcc atctatactt gtattgaccg
    54361 ctaactcacc cgatgcattt acataatacc atttaccacc aacttggaac cattgattga
    54421 ctttcataga accgttgctg ttgaggtagt accatgaacc attaacttgt acccaacctg
    54481 ttgccatgga accatcagta ttataaaaat accacatacc attttcttgt ttccagtctg
    54541 ttgttggagc aactgcttta gctggttcta ctgctacatc tgttccttgg ttagatgtaa
    54601 cagatacagg atacgaagga atagatgatt gctcaggaac aacaactttt tcaggttctc
    54661 tcgtccctct ccttatacgt ctttttacca tctctttagt aatttgacga gaagtagttt
    54721 cttcaattgt tccatcacgt tcatctacag tatagattgt agtaagagta atttaccaat
    54781 ttctcctact tcttctactt cttgactttt atcaagagtt gggccatcga gatattctgt
    54841 ttcgattgga atttcttgga caagaacttg gggcttggtt ctttttttaa caactcttgt
    54901 ttgagagtct ttttttgact taaagtactc tcagttactt gtccactctt tccatctaca
    54961 ttataagtta tcgttgtaac tgttttccca ttctttccta gagtaatctc ttgctcctgt
    55021 cctgcagaaa ggtcattgtc tgcttcatat ttagtagcaa atggaacaag aacttcttca
    55081 accttgcttt tagctggaac tttgataact gtatccgtgg cttcttttct atcaacagta
    55141 acctgttcgg taacataacc agtctctgga ttaacatcgt aggtccttgt cgtagttaca
    55201 tagccatcct ctccatcaat tgtaacagga ttttcactac ggtcttttgt ttcatctttt
    55261 tcataacgaa ttcgcgtact tgaaattttc ttggttacta ccttaggttt agtcgctact
    55321 tttacaataa tatccccatt gtcagcgtca tcatactcta ttccctcttc tttatctcta
    55381 gtatcatctc tgacatattg aatcccatca gcagcatgaa caaaacttgt attcagattc
    55441 ctcctaaaaa taaagttagc ccgattaccg cagaaccaaa aatctttccg agtttacgta
    55501 ttgcatagcg cttattagta ttagattttg ccattacatc ctacttctag tatagcatct
    55561 tttctatcaa acgttaaaca atatacttta tatataaaat agacttagaa tgatatattg
    55621 attattgaac taacacttta actatatcgt aatcaatctc atatataaag gattgcagac
    55681 atcttatcta aatacatgct aatatattta gatacaaaca ttccaacttg ataattttca
    55741 ctcatctttc atcattcctt atacaactat gcagtataaa tagaatagtt ttctcatcag
    55801 aatgagacta ttttaatatt agataatttg atagaaaaaa catgaataaa attggttgaa
    55861 tttaattccc taactcgata gaggattcta ttttaaattt aacaacagct aggattacac
    55921 tataaaaagt acattaccac ctgttcggct ggagaatcta gtcgattagc tccctcttag
    55981 ttacaagctt caagcgattt tttaactaac actaaaccag attaaagaag gaactagaac
    56041 atctgtcttg tactaatcaa tatgctattt taaagtttca aataaacttg gaatgctaat
    56101 tattatattt acaataaata gttgacttcg atagaaacag aaaatagaat tcaacattct
    56161 tccctactta taccataata aataagatcc gcaagatagc cttttctctc tacaccatta
    56221 acaatggttt gtagatagga cattccagcc ttttccatga cacgacctga agctgggttg
    56281 agactggcat aacgtgctct gaccttttga aaacctgctt gagtaaaaca aaagtccaag
    56341 atagctttca aagtctctgt catcatacca tttccccagt aagccttgcc taacacatag
    56401 ccaatttcac agcttaaatc agcctcgtct atcttaacaa tgctgatatc tcctattact
    56461 tgctctgggt tttcttttag acaaatggcc catttataat agttgagatt agtataggaa
    56521 gcaacccaat tgcaaatcga gtttcgagtg atttcgacat caggatgggg atcccaggta
    56581 acataggtca gattctcagc ggatgaagcc caattttgaa acatggcttc tgcatcactc
    56641 tccacaaatc ttcttaaaat caaacgttct gtctgtaata tttgcgtacc gatagatttc
    56701 atgatgctac ctcacttcct tatttctata ctcgtagtaa aaaggctcaa ctcagtaaca
    56761 gctagaaaac gagtttgtct tctaatttct tgacgcagtt gctgcctggt ttgaaatgcg
    56821 ctctagcaag ctttttcaaa cctagtcatc gttgcagggg taagacgatg aaatcgaact
    56881 cttcgagtta ctgaatctgc ctcattttct tatttctaaa ctcggggttc aagatccccc
    56941 agaccttctc tcactttctt atttcaagat gagaggctga aaacctccag tggaggtttt
    57001 tcttgctttt taatttcagg gcaagaagct aaaaaggtcc cccggacctt tttactccca
    57061 aaagtcatca aatacggtga tgggtaagtg gcgtttgtgt tggcctttgt gccaccagtt
    57121 ttcaatggtc gcttgagctt ctgggctgat tgttttgcct tctaggtagt cgtcaatctc
    57181 tgcgtaggtg actccaagtg cgacttcgtc agctaggcct ggtttatctt cttctaggtc
    57241 tgccgttggg attttttcat aaagggctgg ctctgcgcca agtttctgca agagctgttt
    57301 tccttggcgt ttattgaggc ggtaaagagg gagaatatcc gcaccgccgt caccaaactt
    57361 ggtaaagaaa cctgtgatat tttccgcggc gtggtctgtt ccaatgaccg ctccgctatg
    57421 ggaaccagca agggcatact gagcaatcat acggcaacgt gccttgatat tccccttgtt
    57481 gaagtctgaa acaggactac ctgtcgcttc aactgcagct gtcatggcat cagctgattc
    57541 cttgatattc acaaccaagc tgacatctgg ctggatgaag gctagggctt tttgagcatc
    57601 tgcttcatca gcttgcactc cgtatggcag gcggacagcg ataaatttgt agctatcgtc
    57661 tcccgtttca gctcgcagtt cttccatagc taattgcgcc aaacgtcctg ccaaggttga
    57721 gtcttgtccc ccagaaatcc ctagtacaaa ggtttttagg aagggatgtt ttttcagata
    57781 tctttttaag aaatcaatag aacgacggat ttcttcctgg gcatcaatca ctggtttgac
    57841 acccagctct tggataatcg tttcttgcaa actcattctt cttctccttc accaagggct
    57901 tccttgcgca tcttatcaat caagtccatc ttatcttgcc atacatcacg cgccaaatcc
    57961 actggatagt gctgcggatt gagcacacgc ttatactcat cccacaactt gtcaaattcc
    58021 ttacgggcat aatcctgaat gtcagtcaaa ctaggcaagt tgtaaactaa tattccttct
    58081 ttgaagatat ccaccaagag aggaacggca tcaaaattac gaaccgtctt cttgatgtat
    58141 gtataggtcg gatggaacat cttgatttct gtcatgtcgc taatatccac accatcataa
    58201 gtgatatagt cgccttctga cttgcctttt tcacgactgg taatgcgcca cacctgcttc
    58261 ttacctggcg tagaaacttt ttcagcatta ttagacagct taatcgtatt gcgcatctga
    58321 ccagtttcat cttcgattgc aacaatcttg taaaccgccc caagagccgg ctggtcatag
    58381 gctgtaatca gcttggtacc cacaccccag acatcaatct tggccttttg catcttgagg
    58441 ttaaggatgg tattttcatc tagatcatta gaagcataaa tcttagcctc tgtaaatcca
    58501 gcctcatcca gttgctgacg gactttctta gaaatgtagg caatatcccc agagtcaatc
    58561 cgcacaccca taaagttaat ctgatcaccc agctcacgcg ccacctgaat ggcagctggt
    58621 acaccgatgc gaagggtgtc ataggtatcc acaagaaaga cacaattttt gtgggtcgca
    58681 gcgtaagcct tgaaagcttc atagtcattg ccataaacct gtaccaaggc atgggcatgg
    58741 gttcccaaaa caggaatgtc aaagagctta cccgcacgca cgttgctagt tccattggcg
    58801 ccaccaatca cagctgcgcg tgttccccag atggccgcat ccatttcttg agcccgacgt
    58861 gtcccaaact ccatcaaggg ttcatcttcg ataaccgaac gaatacgagc tgccttcgtc
    58921 gccaccaagg tctggtagtt gacgatgttc aaaagagccg tttcgaccaa ctgacattgg
    58981 gctagaggtc cttccacctg cacaatcggt tcattagcaa aaaccaaatc cccttcttgg
    59041 gcagaacgaa cggtcaactc caacttgaaa ttgcgaaggt aatccaagaa cgccccatga
    59101 taaccaagcg actccaaata ggctatatca ctatctgaaa aacgcaagtc ttcaagatag
    59161 ttcacaattc tttccaaacc tgcaaaaacc gcatagccgt tcttaaaagg ctgttggcgg
    59221 aaatacacct caaagaccgc cttcttattg tgaatccctt ggtcaaagta aacctgcatc
    59281 atgttgatct ggtacaagtc cgtgtgcaat gtcaaactat catctggata catacttttc
    59341 ctacttcctt agctagaaac ccatgaaaat tttcaagaac tttcatgtat tccaataaat
    59401 tagtactatt atatcacatt ttagctggat tgagaaaaga gtaacaagct attctccact
    59461 ctccaattca tccatatctt gttcaaattt tttctgagcc cattcgccat agctcttaag
    59521 accaagattg ccaataaaga tccacggaag gtaaatgata taagtaatga cccaagcaga
    59581 caggtattta aaattcaaag gattgtgctg ataaatttct atgttgaatt gataattctg
    59641 caacatcaaa agagccgtaa tagccaaggt taggaaaaaa caacccaaaa tcgtaaaatg
    59701 aaaacgacta tagtaggtca ctcccagata acgggcacga ttgaaaaagt aaaatgtccc
    59761 tatgatgata acgattagca gcatattaga attaaaaagg cttggtgcta atactgaaat
    59821 gatataagat aggagcgaca aagcgatgca gatatagaaa ctttcagagc ccgctttatt
    59881 gaacagttgt tcttctcttt cgtctagtaa ttgataataa taaaatctat ttttcatctt
    59941 cttcctccca aaatagttgg tctagggttt tccctaaaca tctgcaaatg gactggcaga
    60001 gcgagagact gggattgtat ttccccgctt ctatcaaacc aatagtctgg cgcgtcaccc
    60061 cgacagcctc tgccagttga ccttgtgtta aatcacgctc tacccgagct aattttaatt
    60121 ttaaattttt agccaccttc gtcctcctta tagttttaat actcatctac tcttaaaaaa
    60181 tccaaaacca acacaagcta tcagctattt attataaccc cattaatttg cactccagta
    60241 ttatcttcag ccgaaaatca gtattttagg ttgtttgaaa taaacttcct agtttactct
    60301 tttattttta tttagtatta gctttagtag gatcttttaa acgagttttt attgcttata
    60361 tttcttgttt agtttagttg gtttcatatc actattatat aatgcttttg gaaatgagcc
    60421 tagtataagt caaaaacgtg ttgaatagtg aaagcaggag cataccaaga tgactgattt
    60481 ttttattgta ttttaggtat gcaaaataat actaaatgaa actaaaatga atacttcttg
    60541 cttttcttga gagtgaaaaa gtacaataaa atgattgtag tgattagcac aagatactga
    60601 ctaatagaca tcgtatttga agccacaaat acaggtaaag aataaaaaag gaagaagttc
    60661 aattgctttg ataaacaaat cattactagt attcatcatc atcgtattta atatattaga
    60721 gataaagagt agtaaagcta ctaaaatacc aaataccaag ccacttttca atttgtataa
    60781 atagaaaatg taagataata gaaaataaaa caggactaac aaaattgtat tgactacaat
    60841 agctactata aaatttaatc ctaaatcacc tggaataccc aatttactta ctatgactag
    60901 taacacaatg ccattcaaag cataaataat ggaaactgag atagcatata gaaaattaga
    60961 caagacgtaa atcatccgat tcttctgttt atttaatttc atgattataa ccttccttta
    61021 ttttgaacga tttaggtaaa tatctttaag cgtctctttt ttagtttcaa aatcaactac
    61081 tttaatagag ttttcgttaa aaaatttaaa aagctcacta ttttgaatat tcccagacat
    61141 agtaattctc aatccctctt cctaaacaat atcccaaaat tcttgtttgg taatgaaaat
    61201 gtctctatct gtagctgatg aaaaagctat ctcaaacaag aaattatgac tatcttttcc
    61261 tactttttga aatgtcaaaa gcccgttctc caagaaaaga actctctcac aaatttcttc
    61321 aatgtcttct aatttatgac tcgatattaa aattcccaca ttttcatgta aagctaattt
    61381 ttttagaacc gctaaaacta tttgtgatga ttcaatatct aaaccattag tcggttcatc
    61441 taaaatcaat atatcaggtt ccgtaacgag agttagaagc aaagctaatt tttgttttgt
    61501 acccaaagaa taggtcttta cttttttatt aatagactga gtcaaatcta actcttggat
    61561 caaacatcta aatctttctt gattgtagtc aacaccatat aaatttgaca aatattttaa
    61621 attctctaaa cctgttttag ataaaaataa ttttggttct tcgattaaat acccaacatt
    61681 atcactgctt ataatattac ctgaagtcgg ttgattattc tgaacaagaa ttttcatcaa
    61741 cgtactctta ccaactccat ttctccctgc tagaccaaca atttcaccct tgttaagtgc
    61801 aaaatttata tctttgagaa tgattgaatg accataatgc ttacttacat tttttattcc
    61861 tccattaata ttatttgttt tctctttgat tctcattaat tttaaaaagt tgcgcctctt
    61921 tttaacaata ttatatcata tatctaactt aatgcaatat ataaatgtca ttttgtgaaa
    61981 ttttattaac aaaaaactct ctacaacaaa ataatagaga gttttctgct tattaatttt
    62041 tttcaaaata tctaagacat cacttctttg tttaatttga taggctttga tacctgagct
    62101 ccgactttat cacttaaaaa ataaaaaaga cagctaatct cttgcgcatc aagggatttc
    62161 gccattcttt aatctcgttt aagtgttgta tatggagctt tgcataattt tttaaaacta
    62221 aacaactaca ttaagcacga actgtgacgc tggttccatc ttccttataa agattgataa
    62281 gcccctcttt aagagctcga accatgtctc cagcttgaac aggttgtggg actttaatag
    62341 tcaatagttc cattggattt ggagcgcggt cgattttatt gcctttggca tcatgcaaat
    62401 cttcaatata ggtttcaaaa tgacggaaac ctggaccata aaactcaact tggtcccctt
    62461 cgttaatgac gttccgttga cgaatggttg ctgtttgtgt cgcatcatca taagaaatca
    62521 cttcagcgac aaacttgtac tcaggaattt tacgacgagc accaaacaac tgctcatttt
    62581 cagatggtat accatagtaa aatcctgtag ccagttcacg ttgggcaacc ttccacatct
    62641 cgtccaccaa gtcttgtttg atagcttcaa acttttcagg actttcaaga taggcatcca
    62701 cagccgcctt gtagcagttg gttactgttg atacgtagtg aatagactcc actccatacg
    62761 tccttcgatt tttagattgt ccacaccatt ttcaatcata tctggaatgt ggtcaatcat
    62821 agacatgtca acggctgaca ttgaaaattc ttctggaatc tcaccctgca aactcttacg
    62881 ttctttccca aatggcatat cgtaaaggtc gtatttccaa cggcatgact gagaacatcc
    62941 accacggttg gcatcacgca tactctagac ggattgtttt gacaattcta atcttttaga
    63001 ctttgcataa taactgttaa acagtcgaaa attaccccag ttttaacaag tagtcaaaat
    63061 accagataaa ggaaaaaagt ctttaaaatc ttaaaaacgc atagtatcag gtattgaaca
    63121 atcttgatat tatgcgtttt attgtgggaa gatttacttc attttctctt gaaattgagt
    63181 tttctcctac ttcaaaacta gatgatttgc tatttaaaat agcgttcctt atgattttgg
    63241 caacctggat taaagcgaga aaaacaaaag gggcaactta aactttcttt atattgctta
    63301 tatgttagta gttttagaca aacaccacat aaaataggct tatcctgtat caaagataag
    63361 ggatacggct caaaagggtg attttctaat gaatcatgac accgataaca agcataatac
    63421 tttttacaat catagcattg taaagcaata atatccagct tgctatggta atgaatgcat
    63481 cttgtttgct tatccactaa gaaaccctgt gcctctatca tttccttttc ctttcttaag
    63541 ctcgaactgt gacgctggtt ccatcttcct tataaaaatt gatgagtcct tcttttaatg
    63601 cacgaaccat gtctccagct tgaacgggtt gtgggacttt aatagtcaat agttccattg
    63661 gatttggagc gcggtcgatt ttattgcctt tggcatcatg caaatcttca atataggttt
    63721 caaaatgacg gaaacctgga ccataaaact caacttggtc cccttcgtta atgacgtttc
    63781 gttgacgaat ggttgctgtt tgtgtcgcat catcataaga aaccacttca gcgacaaact
    63841 tgtactcagg gattttacgg cgagcaccaa acaactgctc attttcagat ggtataccgt
    63901 agtagaaacc tgttgccaat tcacgttggg caaccttcca catctcgtcc actaagtctt
    63961 gtttgatagc ttcaaacttt tcaggacttt caagataggc atccacagcc gccttgtagc
    64021 agttggttac tgttgatacg tagtgaatag acttcatacg tccttcgatt tttagactgt
    64081 ccacaccatt ttcaatcata tctggaatgt ggtcaatcat agacatgtca acggctgaca
    64141 ttgaaaattc ttctggaatc tcaccctgca aactcttacg ttctttccca aatggcatat
    64201 cgtaaaggtc gtatttccaa cggcatgact gagaacatcc accacggttg gcatcacgca
    64261 tactcatgtg gtttgaaaga gtacaacgtc cagagtatga aatacacata gctccatgga
    64321 caaaggcttc aatttcaaca tctgtacgtt tgcggatctc agctaattct tccattgaaa
    64381 cctcacgcgc taaaacgaca cgagtcaagc ctagctcttt ccagaactca agggtttcat
    64441 agttagtggc actggcttgg gtagaaaggt ggatttcaag gcctggtgct tcagtcgctg
    64501 caatcataat caaggctggg tcagatacga taactgctgc aatcccgata tcacgcagtt
    64561 tacggaacca ctcaccagca ccagcttcat ttccttcgtg cataaccata ttagccgcta
    64621 catagacctt ggcaccatac ttggccgcaa actgcacgcc ttcttccatc tgttcgaaag
    64681 taaagtttcc cgcacggcta cgaagaccat aggcctgacc accgataaag acagcatctg
    64741 ctccatactg aacagctacc tttagcttct ctaaagtccc tgcaggtgat aaaacctcag
    64801 gacgttttaa tgtttttgtc atgatttctc ctatttgcaa tataaaagtt tgacattttt
    64861 ccttctcatt ttatagtaaa taaaggataa aatcaagcct agacggattg ttttgacaat
    64921 tctaatcttt tagactttgc ataataactg ttaaacagtc gaaaattatc ccagttttaa
    64981 caagtagtca aaaagtctag aaaagtaaaa accagtatcc aaagatactg actcgtaaaa
    65041 atacataaat tagtccttag atgactactc ccactctgtt gctcctataa tggaaaagga
    65101 ttgatacagt ctagaatatc gcttttttat ttattattct gatataaaac tgttagaatt
    65161 gattttttgt tttataccca aatatgaata gagacgtagc taataagttg aataacatat
    65221 ttggaaaaat gagaaatagc aatattacta gaacttttag aaacaatcaa tatttaaaaa
    65281 gaaaaagctc aaagaattta ttaaaccatg ttataataga tatagctata attttattta
    65341 taacaagagg atagaaatga ccgaattaga aagaaaaaat cgaaaaatta gctaagaaat
    65401 attctgataa cttaaacatc aaagttcaag agagagttcg tgaaatggca aatgataata
    65461 agagccatta tttgatatac agagttttag gtatttcatt tgaagaagga gaaaatatcg
    65521 atttgtatca aaataaaggt cgttttttat acaaatatgc tggttcattt ttagaagaag
    65581 ctgcagtact atcctttaac gaaaaatttg gtacagaaaa tccttaaaaa gttaacattc
    65641 ctaattctga aagtacaaaa cctaagactt ttgaaattga ttgtttagtc ggagaaaaac
    65701 acgcatacga aataaaatgg tgggatgcaa ctacagatgg agaccatata actaaagaac
    65761 acactagaat aaaagttatt cataacaaag gatatatacc aattcggtta atgttctact
    65821 atccaaatag aactcaagct ataaaaattc agcaaacttt agaaacattg tataacggta
    65881 ttggagggaa atattatgga gattctgcct gggaagattt aagagcagtg accggtattg
    65941 atttacttag tattctaaca gatattgcaa ataaaaaaca ggggtaaaat caaaatgaca
    66001 gtattaaaag gagataactt agaaatatta aaaactattg aatcctcaag tattgattta
    66061 atctatatgg accctccttt ctttacacag aaaacccaaa aattatctaa taacaaaaat
    66121 attatgtatt cattcgaaga tacgtggact tcgattgagg attacaaaga atttttgtct
    66181 gtaagattag aagaatgcaa aagagtgcta aaaaatagtg gcagtatttt cgttcattgt
    66241 gataaaattg caaatcatca tattagatta attttagata atatctttgg agcagatatg
    66301 tttcaaagcg aaattatatg gaactataaa cggtggtcta attcaaaaaa gggattattg
    66361 aacaatcatc aaaacattta cttttattca aagtcaaaag attttaaatt taatacaatt
    66421 tttacagagt attcttctac tacaaatatc gaccaaatac tagtggaacg aaaacgagat
    66481 ggaaactcta aaactatata taaagttgat aataatggta actatattct agcaaaagag
    66541 aaaaatggag ttcccctttc agatgtttgg aatataccat ttcttaatcc aaaagctaaa
    66601 gaaagagtag gttatcctac acaaaaacct attctgttat tagaacaaat tataaagatt
    66661 gctactgata aaaatgatat agttttagac ccgttctgtg gaagtggaac tactttagta
    66721 gcctccaaga ttttgaatag aaattatatg gggattgatt tatctgagga agctatcaat
    66781 ataactcagc aacgtctgga aaatgttata aaaacaagtt cagatttatt gaataaagga
    66841 atcgaagcat atagaaccaa aactgaggaa gaggaaaaca ttcttaaatt attacaggca
    66901 aaaattgttc aaagaaataa aggaattgat ggttttttac ctaaacattt tcaaaaaaaa
    66961 ccgataccta taaaaattca aaaaaataat gaatgtctga atgagagtat ctctttatta
    67021 cagaatgcta taaactccaa aaaacttgat tttggagtag ttataaaaac tcattcagat
    67081 aatttattat ttgattttga tacgattcct gaaaatataa tagtagttga ccattttgaa
    67141 cttacaatcg aaaaatggtt aagtaaaagt caacagttac tatagtttgc aaattattta
    67201 cagaaagaac aaaaaatgct ctgaaacact gatttcaagg cattttttgt tagtttaaaa
    67261 ttactcccat tcttcttttc caaacataca atatatccaa aaccattcaa aatactagat
    67321 tctatttttt ataatatcac taaatccacc taattatagg acgttttcag atttttagtc
    67381 ccgtcccagt cccagtaccg gagaaatatt gttttaatat aatatctctt tttgtcttct
    67441 aagctcttaa aagcaaaaga acaagtaaag agtcaagaca aggataaaaa gtccatatta
    67501 gggcaaataa aaagctttaa gacagatgac aaatctaagt caaataagaa agaccatagc
    67561 aaaggtgcag agagataaat attggcggtc ttcggactgc ctttattttt ttatccattt
    67621 ttcaaatcaa atttattcag actatatatg cacatataca cttaaattca tataaaaaca
    67681 tggcttgtaa aaaattactt taatcacaat aatcgcattt aaaattgtga tgtttgcaag
    67741 ctaaattacg gacttcactt ggaagttttc ccttgtatct tttataatag atagaaaatt
    67801 tgctggcaga tgaatatcca acagattctg ctatctcttt tataggtagt tcagtgttta
    67861 aaagaagagt ttcagctaca ttcattcttt ttctttgagt gtactctgta atgctttgac
    67921 aatatttttc cttaaataaa ttttttaatt tagtaccact cattttagat attttttcaa
    67981 gcgtgccttg atttacattc gttgcaaaat gatcatctaa gaatcttgct acatcttcaa
    68041 gtgctttatc atcatcaatt tcaattttat atttttttct atttaagtat gtgtcaatta
    68101 ctatacttat ccattcattt gcctttgctt taaagaaaaa atcagcggca ggagcgtcca
    68161 tcttacaatt taatatttcc attgccactc tttctaaggc ctttgtaagt attatttgat
    68221 tcgattgaag caaggttgaa taaaaagatt ctggattaat gttaatagat gctaaatgtt
    68281 tttctattag ctctttttta aaaccaatgg aaacagcaag ataacaacaa ttctcgtgta
    68341 ataaaaaaac aaaatcatct tttatattat caaaatcaaa agtacataaa gagtttgcgg
    68401 taatagtttg atacggatta aacttttctc cgtttgcact gacaatgtaa cttgaataaa
    68461 ttgaaacata gtctgacata ctataagtgc tattttgaac tacttcctct ttgatataaa
    68521 aatcatgtat atcgataatg aagctgcctc cttcataaaa ccaatatagg ccttctgcat
    68581 aagttgaatt ctcttttttc caacaaaatg tatgacctgc acttgaatac ttctcattgt
    68641 ttttacattc atctactttc atataatctt ttacaaaatc ataatatgac ataacacact
    68701 atccctttta gacaatattc caattagcct tattaattca aaactattgt attagtaatt
    68761 ataacagatg tataatagaa aagcaatgat agatattatc aattaagcga atttatatct
    68821 aaaagggata ttaaagaaag gagatatgct tatgaagatt tacaaaaaac tatttgctta
    68881 tgtccaagat aagaaatatc ttggggtttt ggccataatt ttttctgcta tatctgctgc
    68941 acttacagta tatggatatt atttaatcta caaatttcta gataagttaa taattaattc
    69001 aaacttatcc ggtgcagaga gtatagcatt aaaatctgtt attacactaa caagtggagc
    69061 gatattttat tttgtctcag gaatgttttc acatatcttg ggatttaggc ttgaaacaaa
    69121 tttaagaaaa aggggaatcg atggtctgga aaaagcaagt tttaggttct ttgacttaaa
    69181 tccatctggt caaataagaa agatcataga tgataatgca gcacaaactc atcaggtggt
    69241 agcacacatg attcccgata gttctcaggc aataatcaca cccgtacttg tacttgcact
    69301 tggctttata gtaagtataa gggttggcat aattttgctt gctcttacta taattggtgg
    69361 cttaatttta ggggcaatga tgggcgagca agaatttatg aagatatacc aagaatccct
    69421 atctaaacta agtgctgaaa ctgttgagta cgtgagagga atgcaagttg taaaaatatt
    69481 taaagcaaat gtagagtctt ttaaaagctt ttataaggcg ataaaagatt actcaaagta
    69541 tgcttatgat tattccctat cttgtaaaag gccttatgtt ttgtatcaat ggttattttt
    69601 tggactgatt gcaattttaa ttattcctat agtttatttt atgactagct tagctagcgc
    69661 aaaggtgatt ttacttgagc ttatcatgat tttattttta tcaggagttc tctttgtttc
    69721 attcatgaga atgatgtggt actccatgta tatttctcaa ggaaattatg cagtagatac
    69781 tttagaggcg ctttacgaag atatgcaaaa agacaaatta gtgcatggta atgtcaataa
    69841 ttttaaaaac tataatatag aatttgagaa tgttagcttt gcttataatg ataaagctgt
    69901 cattgaaaat ttatccttta atttagaaga aggaaagtcc tacgcacttg tcggttcatc
    69961 tggatcaggc aaatcaacag tagcaaaact tatatcaggt ttttacaatg ttaataaagg
    70021 aagcataaag ataggcggga tagcaataag tgaatattct gacgaagcct taattaaagc
    70081 catttccttt gtttttcaag attcaaaatt attcaagaag agcatttatg ataatgtagc
    70141 tttagctaat aaagatgcga cgaaagatga cgttatgaga gccttaaaat tagcaggatg
    70201 cgatttaata ttagacaaat tcccagaaag agaaaataca atcataggct caaaaggtgt
    70261 ttatttatcc ggtggagaaa aacaaagaat tgcaattgct agagcaattt taaaggattc
    70321 caaaattatt attatggatg aagcatcagc atctattgac ccagataacg agtttgaatt
    70381 gcaaaaagct tttaaaaatc ttatgaagga taaaacagtt atcatgattg cacacaggct
    70441 atctacaatt aaagaccttg atgaaattat tgtcatggat agtggaaaaa ttatagaaag
    70501 agggtctgac aaagaattaa tgtcaaaaga tacaaggtat aagagcctgc aagagatgtt
    70561 taacagtgcg aatgaatgga gggtttcaaa tgaaagagtt ttataaaaaa agatttgctc
    70621 ttacagatgg aggagcaaga aatttaagta aagcaacact ggcttcattt ttcgtttatt
    70681 gtataaacat gcttcctgcc atattactta tgatttttgc tcaggaagtt ttggaaaata
    70741 tgggcaaaag caatggcttt tatatagtat tctcagtttt gactttgata gcaatgtata
    70801 ttttgctttc tatcgaatac gataaattat ataacacaac ctatcaagaa agtgcagatt
    70861 taagaataag gacagcggag aatttatcaa aattacctct atcttacttt tctaaacatg
    70921 acatttccga catttcacaa acaatcatgg ctgatattga aggcatagag catgcaatga
    70981 gccactcaat accaaaggtg ggcggcatgg tactgttttt cccattaata tctgtaatga
    71041 tgctagcggg caatgtcaag atgggtttag ctgtaattat tccatctatt ttaagcttta
    71101 tatttatacc tttatctaaa aaatatcagg ttaatggaca gaatagatat tatgatgtct
    71161 taagaaaaaa ctcagaaagc tttcaagaaa atatcgaaat gcaaatggag attaaagcat
    71221 ataatttatc gaaggatatt aaagatgact tatataaaaa aatggaagat agtgagagag
    71281 tacacttaaa ggcggaagta actacaattt taactttgtc tatatcttca atatttagct
    71341 ttatatctct tgctgttgtg atatttgtcg gcgtaaatct aattattaat aaagagataa
    71401 attctctcta ccttatagga tatttactag ctgctatgaa gataaaagac tctttagatg
    71461 catctaaaga gggcttgatg gaaatatttt atttatcgcc caaaatagaa agattaaaag
    71521 aaattcaaaa tcaagatcta caagaaggcg atgactatag cttaaaaaaa tttgatattg
    71581 atctaaaaga tgttgagttt gcctacaata aagacgcaaa agttttaaat ggtgtaagtt
    71641 ttaaagctaa gcagggagag gtcactgctt tggtaggtgc aagtggctgc ggtaaaacaa
    71701 ctatcttgaa acttatatca agactttatg attatgacaa gggacaaatc ttaatcaatg
    71761 gcaaagatat aaaagaaata tcaacagaat ctctttttga taaggtctct atagttttcc
    71821 aagatgtggt tctctttaat caaagcgtta tggaaaatat tagaatcgga aagcaagatg
    71881 caagtgacga agaggttaaa agagcagcaa aacttgcaaa ttgcacagat tttatagaaa
    71941 aaatggataa aggtttcgat acagttattg gtgagaacgg agctgagcta tcaggaggag
    72001 aaagacaaag attatcaata gccagagcct tcttaaaaga tgcgccgata ttgatcttag
    72061 atgagataac agcaagcctt gatgttaaca acgagaaaaa gattcaagag tctttaaata
    72121 atttagttaa agataaaact gttgtaatca tttcacatag aatgaaatcc atagaaaatg
    72181 cagacaagat agtagttctt caaaacggaa gagtagaaag cgaaggtaag catgaagagc
    72241 ttttacaaaa atcaaaaatt tacaaaaatt taatagaaaa gacaaaaatg gcagaagaat
    72301 ttatttatta ggaggactac aatggataat aaaaaattaa aagtaaaaga tttagtaagc
    72361 atcggtgttt ttggcgtaat ttattttgcc ttcatgtttg gagttggtat gatgggcttg
    72421 attccaatat tgttcttaat atacccgaca gtattagcca tagttgcagg aactgttgtt
    72481 atgttattta tggctaaggt tcaaaagcca tgggcactat ttatatttgg tatgatatca
    72541 ccacttgtga tgtttgcagc tggtcatacc tacgtagttg tggttttatc acttatagta
    72601 atgataatag cagaattaat tagaaagatt ggtaattata attcatttaa atacaatatg
    72661 ctttcttatg caatcttcag cacatggata tgtagctctt taatgcaaat gcttttagca
    72721 aaagaaaaat atatggagtg gtctttgatg acgatgggaa aagattatgt tgatgtatta
    72781 gaaaagttaa taacttatcc tcacatggct ttagtagcct taggtgcttt cttaggagga
    72841 attcttggag catatatagg caaggctcta ttgaaaaaac actttgaaaa agcaggcatt
    72901 gtataatgcc tactttttct tcaaatgctc cctttaatcc caatccgatc tctaagatat
    72961 tagtcgtatt tatcacaggc ttaactgtta tgcatagcat aaacatccgt tttgagctgg
    73021 caattgtttg tcttattggt attttgcttt atttgaatgg atacaaaaaa acacttttca
    73081 aatggattat attgtgtggg atactttact ccttgcctaa ttttatggtg ttatctgaat
    73141 taaaccctat agttaagatg tttttgagta tacctattgt tattagaatg tttattttac
    73201 catttatggc agcaagcttt atgataaaga cctcggatgt aggcgcaata atttcatcga
    73261 tggataagct taagatttca aagaatgtat ccatacctat tgcggttatg tttagattct
    73321 tcccatcttt taaggaggag aagaaaaaca tcaaaatggc tatgagagta agagggataa
    73381 attttaaaaa cccagtcaaa tatcttgaat atgtttctgt gccactactc attatatcat
    73441 ctaatatatc agatgacatt gcaaaagcgg cagaaacaaa ggcaatagaa aatccaattg
    73501 ccaagaccag atacattcgc gtaaagatac agctaattga ttttgtttat gttttagcgg
    73561 ttgttggact tattgtggga ggcttaatat ggttgaaata aaaaatttaa gtcttgatta
    73621 tggtgaagag catatattag atgatatatc actatccata gccgagggag agtgcgtgct
    73681 atttacagga aaaagtggaa atggtaagtc atctttaata aattcaatca atggactagc
    73741 tgtaaggtat gacaacgcaa agacaaaggg cgaaatcatt attgatggta agaatataaa
    73801 aaatttggaa ctttatcaaa tctcaatgct tgtttcaact gtttttcaaa atcctaagac
    73861 atattttttt aatgtcaata cgacattaga attattattt tatttggaaa atatcggtct
    73921 tgcaagagaa gagatggaca ggcgtttgaa ggatatgctt aagatattcc cgataaaaaa
    73981 tcttttgaac agaaatatat ttaatctatc cggcggtgaa aaacaaattc tttgcattgc
    74041 agcttcttat atagcaggta caaagattat agttatggat gagccttcat cgaatttaga
    74101 tattaaaagc ataagtgttt tggcaaagat gctaaagata ttaaaagaga aaggtataag
    74161 cataattgtt gcagagcata gaatttatta tttgatggac atagttgacc gtgtattttt
    74221 aatagataaa ggaaagctta aaaaaactta tactagaagt gaatttttaa agctagataa
    74281 aaatgaatta aatgctttaa gtttaagaga taaagaatta agtaaattaa aagttcctta
    74341 tttaaaagaa ggtggagagt atcagataaa aaatcttagc tacaaattta ctgatgatga
    74401 gtgtttaagc ttaaaagata tttcattcaa gcttgggaaa atttatggca taataggatc
    74461 caacggacga ggaaaatcaa cgcttttaag atgtttaata ggtcttgaga aaaaatcaaa
    74521 agaagaaatt tattttaagg gagagaagct atctaaaaaa gaaagactca aaaactcttc
    74581 acttgttatg caagatgtaa atcatcaatt attcacagat gaagtattca acgagcttag
    74641 attaggagta aagaattttg atgaagaaaa ggcgaaaatc attttaaaag atttaggcct
    74701 ggacgaattt attgaaaggc atccgatgag tttatcagga gggcaaaagc aaaggcttgc
    74761 aatagcatct gttatgtgca agacttctcc atttgtcttt tttgacgaac cttcaagtgg
    74821 tatggattat tccaatatga taaaaatatc tgaactgatt aataagtata aaaccatgga
    74881 taaaataatt tttattgttt cccatgatat agaattttta aatgaagtgg cagatgaaat
    74941 ttttgaattg taaaatagag tctgttaaac atgtctatag aactagtaaa ttgtctaaaa
    75001 atttaaaaga tactaacaca tattgatatt tattagaaaa ttaacttcag gatttttaca
    75061 gtatttataa actttataat atgtatttat agtattaata atttccatat ctttagggaa
    75121 attctttatt tacttaccat aattaaagag atgagagata aatatcggca gtcttcggac
    75181 tgcctttatt tttttactta atttaatgca gtaaatcata cgattgaaag gaatctgcgt
    75241 tatatgctat aattaggtgg ttaatctata catttagaaa ggtaaaatat agaattggag
    75301 aatgatatgg gattttcata taataaattg taaccgtcca ataacgaagt atattgaaaa
    75361 atctccagac tagagaactc acggata
//
LOCUS       DAVBOD010000002        72421 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 640-05
            SAMEA1012484-rid20186543.denovo.002, whole genome shotgun sequence.
ACCESSION   DAVBOD010000002 DAVBOD010000000
VERSION     DAVBOD010000002.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012484
            Sequence Read Archive: ERR059358
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 72421)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 72421)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979948.1
            Genome Coverage       :: 595x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:03:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,266
            CDSs (total)                      :: 2,219
            Genes (coding)                    :: 2,091
            CDSs (with protein)               :: 2,091
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 71 of 128
            Pseudo Genes (incomplete)         :: 50 of 128
            Pseudo Genes (internal stop)      :: 33 of 128
            Pseudo Genes (multiple problems)  :: 22 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..72421
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012484-rid20186543.denovo.002"
                     /strain="NIG 640-05"
                     /db_xref="taxon:1313"
     gene            complement(842..1000)
                     /locus_tag="VQ862_000079"
     CDS             complement(842..1000)
                     /locus_tag="VQ862_000079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3114501.1"
                     /translation="MGDKPISFRDADGNFVSAADVWNEKKLEELFNRLNPNRALRLAR
                     TKKENPSQ"
     gene            complement(1010..2320)
                     /gene="obgE"
                     /locus_tag="VQ862_000080"
     CDS             complement(1010..2320)
                     /gene="obgE"
                     /locus_tag="VQ862_000080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase ObgE"
                     /protein_id="HET3114502.1"
                     /translation="MSMFLDTAKIKVKAGNGGDGMVAFRREKYVPNGGPWGGDGGRGG
                     NVVFVVDEGLRTLMDFRYNRHFKADSGEKGMTKGMHGRGAEDLRVRVPQGTTVRDAET
                     GKVLTDLIEHGQEFIVAHGGRGGRGNIRFATPKNPAPEISENGEPGQERELQLELKIL
                     ADVGLVGFPSVGKSTLLSVITSAKPKIGAYHFTTIVPNLGMVRTQSGESFAVADLPGL
                     IEGASQGVGLGTQFLRHIERTRVILHIIDMSASEGRDPYEDYLAINKELESYNLRLME
                     RPQIIVANKMDMPESQENLEEFKKKLAENYDEFEELPAIFPISGLTKQGLATLLDATA
                     ELLDKTPEFLLYDESDMEEETYYGFDEEEKAFEISRDDDATWVLSGEKLMKLFNMTNF
                     DRDESVMKFARQLRGMGVDEALRARGAKDGDLVRIGKFEFEFVD"
     gene            complement(2384..2518)
                     /locus_tag="VQ862_000081"
     CDS             complement(2384..2518)
                     /locus_tag="VQ862_000081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4044 domain-containing protein"
                     /protein_id="HET3114503.1"
                     /translation="MAFGDNGNRKKTMFEKITLFIVIIMLVASLLGIFATAIGALSNL
                     "
     gene            complement(2577..2753)
                     /locus_tag="VQ862_000082"
     CDS             complement(2577..2753)
                     /locus_tag="VQ862_000082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HET3114504.1"
                     /translation="MRSGRDKKIAGVCAGVAHYLDMDPTIVQVIWGVLTCCYGAGIVA
                     YIILWIIAPVATDY"
     gene            complement(2784..4109)
                     /locus_tag="VQ862_000083"
     CDS             complement(2784..4109)
                     /locus_tag="VQ862_000083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HET3114505.1"
                     /translation="MRIGLFTDTYFPQVSGVATSIRTLKTELEKQGHAVFIFTTTDKD
                     VNRYEDWQIIRIPSVPFFAFKDRRFAYRGFSKALEIAKQYQLDIIHTQTEFSLGLLGI
                     WIARELKIPVIHTYHTQYEDYVHYIAKGMLIRPSMVKYLVRGFLHDVDGVICPSEIVR
                     DLLSDYKVKVEKRVIPTGIELAKFERPEIKQENLKELRSKLGIQDGEKTLLSLSRISY
                     EKNIQAVLVAFADVLKEEDKVKLVVAGDGPYLNDLKEQAQNLEIQDSVIFTGMIAPSE
                     TALYYKAADFFISASTSETQGLTYLESLASGTPVIAHGNPYLNNLISDKMFGTLYYGE
                     HDLAGAISEALIATPDMNEHTLSEKLYEISAENFGKRVHEFYLDAIISNNFQKDLAKD
                     DTVSQRIFKTVLYLPQQVVAVPVKGSRRMLKASKTQLISMRDYWKDHEE"
     gene            complement(4125..5168)
                     /gene="cpoA"
                     /locus_tag="VQ862_000084"
     CDS             complement(4125..5168)
                     /gene="cpoA"
                     /locus_tag="VQ862_000084"
                     /EC_number="2.4.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosylglucosyldiacylglycerol synthase"
                     /protein_id="HET3114506.1"
                     /translation="MEKKKLRINMLSSSEKVAGQGVSGAYRELVRLLHRAAKDQLIVT
                     ENLPIEADVTHFHTIDFPYYLSTFQKKRSGRKIGYVHFLPATLEGSLKIPFFLKGIVK
                     RYVFSFYNRMEHLVVVNPMFIEDLVAAGIPREKVTYIPNFVNKEKWHPLPQEEVVRLR
                     TDLGLSDNQFIVVGAGQVQKRKGIDDFIRLAEELPQITFIWAGGFSFGGMTDGYEHYK
                     KIMENPPKNLIFPGIVSPERMRELYALADLFLLPSYNELFPMTILEAASCEAPIMLRD
                     LDLYKVILEGNYRATAGREEMKEAILEYQANPATLKDLKEKAKNISREYSEEHLLQIW
                     LDFYEKQAALGRK"
     gene            complement(5283..5612)
                     /locus_tag="VQ862_000085"
     CDS             complement(5283..5612)
                     /locus_tag="VQ862_000085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HET3114507.1"
                     /translation="MAYTEEQIENIKTRILTALEEVIDPELGIDIVNLGLIYEIRFDG
                     DTGQTEIDMTLTTMGCPLADLLTDQIYDAMIEVPEVTDTEVKLVWYPAWTVEKMSRYA
                     RIALGIK"
     gene            complement(5626..6735)
                     /gene="rpoD"
                     /locus_tag="VQ862_000086"
     CDS             complement(5626..6735)
                     /gene="rpoD"
                     /locus_tag="VQ862_000086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoD"
                     /protein_id="HET3114508.1"
                     /translation="MATKQKEVTTFDVQVAEFIRNHKQKGTATDDEINASLVIPFTLD
                     ADGIEDLLQRIQDAGISITDNEGNPSARVLSNEEEPELSDEDLIGSTSAKVNDPVRMY
                     LKEIGVVPLLTNEEEKELALAVEAGDIEAKQRLAEANLRLVVSIAKRYVGRGMQFLDL
                     IQEGNMGLMKAVDKFDYSKGFKFSTYATWWIRQAITRAIADQARTIRIPVHMVETINK
                     LVREQRNLLQELGQDPTPEQIAERMDMTPDKVREILKIAQEPVSLETPIGEEDDSHLG
                     DFIEDEVIENPVDYTTRIVLREQLDEILDTLTDREENVLRLRFGLDDGKMRTLEDVGK
                     VFNVTRERIRQIEAKALRKLRQPSRSKPLRDFIED"
     gene            complement(6738..8498)
                     /gene="dnaG"
                     /locus_tag="VQ862_000087"
     CDS             complement(6738..8498)
                     /gene="dnaG"
                     /locus_tag="VQ862_000087"
                     /EC_number="2.7.7.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000227865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="HET3114509.1"
                     /translation="MVDKQVIEEIKNKANIVEVIGDVISLQKAGRNYLGLCPFHGEKT
                     PSFNVVEDKQFYHCFGCGRSGDVFKFIEEYQGVPFIEAVQILGQRVGIEVEKPLYSEQ
                     KSASPHQALYDMHEDAAKFYHAILMTTTMGEEARNYLYQRGLTDEVLKHFWIGLAPPE
                     RNYLYQRLSDQYREEDLLDSGLFYLSDANQFVDTFHNRIMFPLTNDQGKIIAFSGRIW
                     QKTDSQTSKYKNSRSTAIFNKSYELYHMDRAKKSSGKASEIYLMEGFMDVIAAYRVGI
                     ENAVASMGTALSREHVEHLKRLTKKLVLVYDGDKAGQAAILKALDEIGDMPVQIVSMP
                     DNLDPDEYLQKNGPEDLAYLLTKTRISPIEFYIHQYKPENSENLQAQIEFIEKIAPLI
                     VKEKSIAAQNSYIHILADSLASFDYAQIEQIVNESRQVQRQNRMERISRPTPITMPVT
                     KQLSAIMRAEAHLLYRMMESPLVLNDYRLREDFAFATPEFQVLYDLLGQYGNLPPEVL
                     AEQTEEVERAWYQVLAQDLPAEISPQELSEVEMTRNKALLNQDNMRIKKKVQEASHVG
                     DTDTALEELERLISQKRRME"
     gene            complement(8588..9346)
                     /locus_tag="VQ862_000088"
     CDS             complement(8588..9346)
                     /locus_tag="VQ862_000088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000125420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3114510.1"
                     /translation="MTAIVELKNATKIVKNGFDEEKIILNDVSLEIFERDFITILGGN
                     GAGKSTLFNTIAGTLSLTSGTIRILGEDLTKFSPEKRAKYLSRVFQDPKMGTAPRMTV
                     AENLLIAKFRGEKRGLLPRRLTSYKDEFQVTIEKVGNGLEKHLNTPIEFLSGGQRQAL
                     SLLMATLKRPELLLLDEHTAALDPKTSVALMELTDEFVKKDQLTALMITHHMEDALKY
                     GNRLIVMKEGRIIQDLNQEEKAKMKISDYYQLFE"
     gene            complement(9343..10209)
                     /locus_tag="VQ862_000089"
     CDS             complement(9343..10209)
                     /locus_tag="VQ862_000089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET3114511.1"
                     /translation="MIVSIISQGFVWAILGLGIFMTFRILNFPDMTTEGSFPLGGAVA
                     VTLITKGVNPFLATLVAVGAGCLAGMAAGLLYTKGKIPTLLSGILVMTSCHSIMLLIM
                     GRANLGLLGTKQIQDVLPFDSDLNQLLTGLIFVSIVIALMLFFLDTKLGQAYIATGDN
                     PDMARSFGIHTGRMELMGLVLSNGVIALAGALIAQQEGYADVSRGIGVIVVGLASLII
                     GEVIFKSLSLAERLVTIVVGSIAYQFLVWAVIALGFNTSYLRLYSALILAVCLMIPTF
                     KQTILKGAKLSK"
     gene            complement(10278..11282)
                     /locus_tag="VQ862_000090"
     CDS             complement(10278..11282)
                     /locus_tag="VQ862_000090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HET3114512.1"
                     /translation="MKNKRLIGIIAALAVLVAGSLIYSSMNKSEAQNNKDEKKITKIG
                     VLQFVSHPSLDLIYKGIQDGLAEEGYKDDQVKIDFMNSEGDQSKVATMSKQLVANGND
                     LVVGIATPAAQGLASATKDLPVIMAAITDPIGANLVKDLKKPGGNITGVSDHNPAQQQ
                     VELIKALTPNVKTIGALYSSSEDNSKTQVEEFKAYAEKAGLTVETFAVPSTNEIASTV
                     TVMTSKVDAIWVPIDNTIASGFPTVVSSNQSSKKPIYPSATAMVEVGGLASVVIDQHD
                     LGVATGKMIVQVLKGAKPADTPVNVFSTGKSVINKKIAQELGITIPESVLKEAGQVIE
                     "
     misc_binding    complement(11395..11612)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(11695..14391)
                     /gene="ppc"
                     /locus_tag="VQ862_000091"
     CDS             complement(11695..14391)
                     /gene="ppc"
                     /locus_tag="VQ862_000091"
                     /EC_number="4.1.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000058210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate carboxylase"
                     /protein_id="HET3114513.1"
                     /translation="MSLQKLENYSNKSVVQEEVFILTELLEDITKNMLAPETFEKIIQ
                     LKELSTQEDYQGLNRLVTSLSNDEMVYISRYFSILPLLINISEDVDLAYEINHQNNID
                     QDYLGKLSTTIKLVAEKENAVEILEHLNVVPVLTAHPTQVQRKSMLDLTNHIHSLLRK
                     YRDVKLGLINKDKWYNDLRRYIEIIMQTDMIREKKLKVTNEITNAMEYYNSSFLKAVP
                     HLTTEYKRLAQAHGLNLKQAKPITMGMWIGGDRDGNPFVTAKTLKQSALTQCEVIMNY
                     YDKKIYQLYREFSLSTSIVNVSKQVREMARQSKDNSIYREKELYRRALFDIQSKIQAT
                     KTYLIEDEEVGTRYETANDFYKDLIAIRDSLLENKGESLISGDFVELLQAVEIFGFYL
                     ASIDMRQDSSVYEACVAELLKSAGIHSRYSELSEEEKCDLLLKELEEDPRILSATHAE
                     KSELLAKELAIFKTARVLKDKLGDDVIRQTIISHATNLSDMLELAILLKEVGLVDTER
                     ARVQIVPLFETIEDLDHSEETMRKYLSLSLAKKWIDSRNNYQEIMLGYSDSNKDGGYL
                     SSCWTLYKAQQQLTAIGDEFGVKVTFFHGRGGTVGRGGGPTYEAITSQPLKSIKDRIR
                     LTEQGEVIGNKYGNKDAAYYNLEMLVSAAINRMITQKKSDTNTPNRYEAIMDQVVDRS
                     YDIYRDLVFGNEHFYDYFFESSPIKAISSFNIGSRPAARKTITEIGGLRAIPWVFSWS
                     QSRVMFPGWYGVGSSFKEFINKNPENIAILRDMYQNWPFFQSLLSNVDMVLSKSNMNI
                     AFEYAKLCEDEQVKAIYEIILNEWQVTKNVILAIEGHDELLADNPYLKASLDYRMPYF
                     NILNYIQLELIKRQRRGELSSDQERLIHITINGIATGLRNSG"
     gene            complement(14411..15640)
                     /locus_tag="VQ862_000092"
     CDS             complement(14411..15640)
                     /locus_tag="VQ862_000092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HET3114514.1"
                     /translation="MKISKRHLLNYSILIPYLLLSILGLIVVYSTTSAILIEEGKSAL
                     QLVRNQGIFWIVSLILIALIYKLRLDFLRNERLIILVILIEMLLLFLARFIGISVNGA
                     YGWISVAGVTIQPAEYLKIIIIWYLAHRFSKQQEEIATYDFQVLTQNQWLPRAFNDWR
                     FVLLVLIGSLGIFPDLGNATILVLVSLIMYTVSGIAYRWFSTILALVSATSVFVLTTI
                     SLIGVETFSKIPVFGYVAKRFSAFFNPFADRADAGHQLANSYFAMVNGGWFGLGLGNS
                     IEKRGYLPEAHTDFVFSIVIEEFGFVGASLILALLFFMILRIILVGIRAENPFNAMVA
                     LGVGGMMLVQVFVNIGGISGLIPSTGVTFPFLSQGGNSLLVLSVAVAFVLNIDASEKR
                     AKLYRELENQPMNLLLK"
     gene            complement(15796..16098)
                     /locus_tag="VQ862_000093"
                     /pseudo
     CDS             complement(15796..16098)
                     /locus_tag="VQ862_000093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
     gene            complement(16546..16767)
                     /locus_tag="VQ862_000094"
     CDS             complement(16546..16767)
                     /locus_tag="VQ862_000094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000285460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET3114515.1"
                     /translation="MYRRLRDLREDHDLTQKQIAKILSFTDSAYAKIERGEHTLTADI
                     LVTLSNFYDVSTDYLLGLTDFPDKIRFRK"
     gene            complement(17447..18658)
                     /locus_tag="VQ862_000095"
                     /pseudo
     CDS             complement(17447..18658)
                     /locus_tag="VQ862_000095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880290.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
     gene            complement(18660..19904)
                     /locus_tag="VQ862_000096"
     CDS             complement(18660..19904)
                     /locus_tag="VQ862_000096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000548397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxylate--amine ligase"
                     /protein_id="HET3114516.1"
                     /translation="MHIVLFRYSARVVKLKYLYNRNVVIIAPEVQRKKYEDYLAEGNN
                     LPKVIFLEDFILPNIILEIRRISQNTEVESITTLSEEDMDIVGFLNDHFVEKNTHSVS
                     NLLFKDKYFMRSFLVGVVNQPYFRLLESENDLRVFWNNCKSSAAILKPRNEAGSNGIK
                     KVYPNEKIDSVYFEKNYIIEEYIDIDNMITCDGYSIGSEIKRFYVHEYEELLFNTLSS
                     SGYYLVRTSSLYNDSEKIEYIEKALEECRKVLNVFSINSEITPFHFEWFLELSTGKIV
                     FCEVGKRFGGGDIPQLIEDSHGVDVIKEYWDILTNSQVLKKINFSKVISRPANISATF
                     ALYRKQGKVIEVPDEKELAWAKKVYIFIKPNTYYKVSENVVENSMFVQFNCKNSCEFE
                     KRLDELKHISQKFKYVITDSGE"
     gene            complement(19928..20956)
                     /gene="galE"
                     /locus_tag="VQ862_000097"
     CDS             complement(19928..20956)
                     /gene="galE"
                     /locus_tag="VQ862_000097"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000838666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HET3114517.1"
                     /translation="MKSLLITGGAGYIGSHTVLDLLDNNYEVTIIDDLSNSKKKVIES
                     IKQISKKSRNLHFYKIDLKNEEKLENVFKRHNFDGVIHFAGYKAVGESVVEPLKYYEN
                     NLLSTINILKLMKKYKVFNFVFSSSATVYESTPIMPFYETNPLKASNPYGRTKQYIEV
                     LLNDLFISNSNWKIVCLRYFNPLGAHESGDLGEDPNGIPNNLVPYITQVAIGKLPYLN
                     IFGVDYSTPDGTCIRDYVHVNDLADGHRKALEYIFNTDEGLYEVINLGSGVGFSVFEI
                     LHSLESVIGSYIPYKITSRRAGDMDVSIADISKAEELLGWKPRYDIMKMCQDTWKWQQ
                     KHPNGYDD"
     gene            complement(20958..21629)
                     /locus_tag="VQ862_000098"
     CDS             complement(20958..21629)
                     /locus_tag="VQ862_000098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000620361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3114518.1"
                     /translation="MIRLPNKFKGNNITLEVKLNKAVDASVLYPDVKSLDQELYRQLQ
                     SVESFYLTFSDMYSEINENNEILYTEIIFKIPLCIGEDYFNFPVVSYVSNPYSLIRGF
                     YLGFHKELDCNYVFDDVELHFFREGICEFNFEFKNQNSIITAELPREYNYPLILFNNS
                     NLVNQYGKYTLLDIDKYKLESRKIFEFPEISIGNFLGSEAKSNRVIFSQDKFQINGIK
                     NMEVN"
     gene            complement(21632..22726)
                     /locus_tag="VQ862_000099"
     CDS             complement(21632..22726)
                     /locus_tag="VQ862_000099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000490588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3114519.1"
                     /translation="MFSEIIKKYDIVTLKDSGFLRGDWFIGSALMAHDYESLKEGIYF
                     YPQETIWTRILDLEYINPYWEIYNQTYNFLLVNKQDSLAMNFLTSLLREIEVISSKTL
                     DFVVITSNEHLIRNLIDRDYYIITKEIPFFIENSKVGNYFKIFVKNGGQFIPIIDCTE
                     FKIQSKKYFEININKFYLKLLDYFLHGEIPEKFKFFGNTSNFNIESLFLEFIDSQENI
                     RVVSLLDCLIQLSSKNIEISGNYKGHTVKKILKKFALYSVITKLDITKVNHLLRNDYI
                     YFLMKEIDNITKKYPKLIQKYPRDILSDRYGITNEVYRYLIGENLHIKINHKLDEVRY
                     FTDIPFIDTSLSIEEFDKIVSKILKIKVGG"
     gene            complement(22730..23260)
                     /locus_tag="VQ862_000100"
     CDS             complement(22730..23260)
                     /locus_tag="VQ862_000100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000586362.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3114520.1"
                     /translation="MIINTLGPTATDCFYAINRIKLKVDVIVLYDSFDSIVNCFDKLK
                     GQYILLPVAFESSIKNYSWKDFNFEYHKRIEIVDSFHSFTKGMVLIENCNYKINRAII
                     QPATEILMLNYLKKKSMDLRIDFTHSKVMANKKFLEEGYRFSIVSQETIINNDDIIIC
                     ETFSPEMIWCLYRVKG"
     gene            complement(23257..23979)
                     /locus_tag="VQ862_000101"
     CDS             complement(23257..23979)
                     /locus_tag="VQ862_000101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase"
                     /protein_id="HET3114521.1"
                     /translation="MITYRNDLLSKELDILISFFKKCEVGKISLVITGSLARGNPRIK
                     DGKLESDIDILVIVDSIQQLISIKKTLEGRFHFVHKISLIFCLKERINRSRYRGIINS
                     IRSVDNLLVDNLHIKNQIIEALDSPTNIVEQTRSMIQEFCYYSSKYLISKNNYLELKL
                     EKYWKEIATLNHIDKKIKHLDFERIFAVLKEHKIQILDSSEYFFQNVKTSENIYLEMR
                     DLVSLENQGLDFEHCILSLGER"
     gene            complement(23966..24835)
                     /locus_tag="VQ862_000102"
     CDS             complement(23966..24835)
                     /locus_tag="VQ862_000102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000680920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyisobutyrate dehydrogenase"
                     /protein_id="HET3114522.1"
                     /translation="MKHKKVLIIGYGIMTRGILKILKQSKKYNIYLYSRHLNSTINGI
                     IFIREDELPDAINQVDFIITCFSNHIETDNFINEFLLNIQSLRKTIVIDFTTSRIDCV
                     EKFKKTVEIKGGYYIEAPFTGGKLGSNSGQLSIFLHIDEGVNYNKKELMELLKLISKK
                     IYFFEKSTEPTKFKLIYNSWGAYLLYSIKLFNPLQYDFSPKSLEVANTIVCNDGWMSL
                     VCNSKLEQINDQDFDDIHFRVEYMVKDLEYANFSVFHDEVKEINYLLQQYRDCLVTDS
                     GKDYTVIGKYDNL"
     gene            complement(24939..25010)
                     /locus_tag="VQ862_000103"
     CDS             complement(24939..25010)
                     /locus_tag="VQ862_000103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_128650800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SHP2/SHP3 family peptide pheromone"
                     /protein_id="HET3114523.1"
                     /translation="MKKISKFFPILMLVMDIIIIVGG"
     gene            25092..25944
                     /locus_tag="VQ862_000104"
                     /pseudo
     CDS             25092..25944
                     /locus_tag="VQ862_000104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016182753.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Rgg/GadR/MutR family transcriptional regulator"
     gene            complement(25989..27853)
                     /locus_tag="VQ862_000105"
                     /pseudo
     CDS             complement(25989..27853)
                     /locus_tag="VQ862_000105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000261806.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
     gene            complement(27840..28138)
                     /locus_tag="VQ862_000106"
                     /pseudo
     CDS             complement(27840..28138)
                     /locus_tag="VQ862_000106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016480038.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MobC family plasmid mobilization relaxosome
                     protein"
     gene            complement(28214..28573)
                     /locus_tag="VQ862_000107"
     CDS             complement(28214..28573)
                     /locus_tag="VQ862_000107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000003746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3114524.1"
                     /translation="MSEQYRDIRKEVNLTADELKQIEKMMEVDNYRHFSPFVRDKILM
                     TDDKQLAAKEWFSLWQSQKFEQISRDVHLVLIIARENHQVTQEHVSILLTCVQELIVE
                     VNQAQPLSREFCEKYMG"
     gene            complement(29392..30549)
                     /locus_tag="VQ862_000108"
     CDS             complement(29392..30549)
                     /locus_tag="VQ862_000108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001213952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3114525.1"
                     /translation="MRGFNNKIKSVYQELTNSKEKFGSFHKTLIHLHTPVSYDYKLFS
                     NWTATKYRKITEDELYDIFFENKKIKVDKTIFFSNFDKVVFSSSKEYISFLMLAEAII
                     KNGIEIVVVTDHNTTKGIKKLQMAVSIIMKNYPIYDIHPHILHGVEISAADKLHIVCI
                     YDYEQESWVNQWLSENIISKKDGSYQHSLTIMKDFNNQKIVNYIAHFNSYDILKKGSH
                     LSGAYKRKIFSKENTRFLEFNINSKESSQQLDILYKEVGVLSLGQKVVAMLDFLLAYS
                     DYSKDFRPLIIDQPEDNLDNRYIYRHLVQQFRDVKAQRQIILATHNATIVTNSMTDQV
                     VIMESDGVNGWIESQGYVSEKYIKNHIINQLEGGKDSFKHKMSIYETALSE"
     gene            complement(30577..31338)
                     /locus_tag="VQ862_000109"
     CDS             complement(30577..31338)
                     /locus_tag="VQ862_000109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zeta toxin family protein"
                     /protein_id="HET3114526.1"
                     /translation="MEIQDYTDSEFKHALARNLRSLTRGKKSSKQPIAILLGGQSGAG
                     KTTIHRIKQKEFQGNIVIIDGDSFRSQHPHYLELQQEYGKDSVEYTKDFAGKMVESLV
                     TKLSSLRYNLLIEGTLRTVDVPKKTAQLLKNKGYEVQLALIATKPKLSYLSTLIRYEE
                     LYAINPNQARATPKEHHDFIVNHLVDNTRQLEELAIFERIQIYQRDRSCVYDSKENTT
                     SAADVLHELLFGEWSQVEKEMLRVGEKRLNELLEK"
     gene            complement(31338..31814)
                     /locus_tag="VQ862_000110"
     CDS             complement(31338..31814)
                     /locus_tag="VQ862_000110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003042293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET3114527.1"
                     /translation="MIGKNIKSLRKTHDLTQPEFARIIGISRNSLSRYENGTSSVSTE
                     LIDIICQKFNVSYVDIVGEDKMLNPVEDYELTLKIEIVKERGANLLSRLYRYQDSQGI
                     SIDDESNPWILMSDDLSDLIHTNIYLVETFDEIERYSGYLDGIERMLEISEKRMVA"
     gene            complement(32259..32714)
                     /locus_tag="VQ862_000111"
     CDS             complement(32259..32714)
                     /locus_tag="VQ862_000111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000500472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3114528.1"
                     /translation="MGAARDFLELINHKGLPLFNPLVGDSHVNNRQEYDNTGSGNLQP
                     EKWNETAKQLYNAIMWLIILWNAKPDTPLFNFKDEVIKYKTYEPFESSIKRVNTTIKN
                     GSKGKTLTEMINGYRADNDIRDEICNFNILKNKIRDMKDQQGNTMESYF"
     gene            complement(32989..34726)
                     /locus_tag="VQ862_000112"
                     /pseudo
     CDS             complement(32989..34726)
                     /locus_tag="VQ862_000112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511339.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glycosidase"
     gene            complement(34889..35773)
                     /locus_tag="VQ862_000113"
     CDS             complement(34889..35773)
                     /locus_tag="VQ862_000113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000710121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
                     /protein_id="HET3114529.1"
                     /translation="MKKAMVIINPTSGGEKALDYKEKLENKAKEYFEYVETKITEKAL
                     DATHFAEEASREQYDAVVVFGGDGTVNEVISGIDERDYIPKLGIIPGGTGNLITKLLE
                     INQDIDGAIDELDFDLINKIDIGKANDNYFGYIFSIGSLPEAIHNVEIEDKTKFGILT
                     YAVNTMKSVMTDQVFNIKVETENGNYVGEASHVLVLLTNYFADKKIFEENKDGYANIL
                     ILKDASIFSKLSVIPDLLKGDVVANDNIEYIKARNIKISSDSELESDVDGDKSDNLPV
                     EIKVLAQRVEVFSKPKED"
     gene            complement(35885..36739)
                     /locus_tag="VQ862_000114"
     CDS             complement(35885..36739)
                     /locus_tag="VQ862_000114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000900021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ADP-ribosylglycohydrolase family protein"
                     /protein_id="HET3114530.1"
                     /translation="MLGAIIGDIVGSVYEWNNIKTKDFPLFRKDCFFTDDTVMTCAVA
                     EAIMNGGQKDDFIDAMKKYGRMYPNADYGARFNAWLNSDNREPYNSFGNGSAMRISPC
                     AWIMDCGFYAKTGMWPSSRGLTSLSAEVTHNHPEGVKGAMATADAIFLCRFYFGGYCR
                     EYEQSINDNPTECKRRIKDYIEKEYDYNLSQTLDEIRPNYRFNETCQETVPQAIIAFL
                     ESRDFEDAIRNAISLGGDSDTLAAITCSIAEAAYGIPDWIKDKAYSYLDEPLKDVVRR
                     WENRIKAY"
     gene            complement(36797..37555)
                     /locus_tag="VQ862_000115"
     CDS             complement(36797..37555)
                     /locus_tag="VQ862_000115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000262024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="HET3114531.1"
                     /translation="MVVYIRQSKLPSEVSINKYNAQVGAYLQGEEVILYQSFSEIKEL
                     TSEDIVVDYIMETRALLKMMGLNVPVHDYPIELKEFYGRKIYAGILGEIVNIPDNWGK
                     FIKPKAGSKVFTGRVVNGTHDLIGIGLPFDYPIWISEVVEFIAEWRCFVLDGRVLDVR
                     PYTGDYHAQFDASVIDEAISCWKDAPIAYGLDIGVTRDGRTLVVEVNDGYALGNYGLS
                     PLKSINFHRARWKEMVKPYFEKNEIFKIQQDVIF"
     gene            complement(37617..37805)
                     /locus_tag="VQ862_000116"
     CDS             complement(37617..37805)
                     /locus_tag="VQ862_000116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000179767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopG family transcriptional regulator"
                     /protein_id="HET3114532.1"
                     /translation="MATDKNRIMISLDDKNLEKLENLVEDARDRRGMRLTKSQVIELL
                     LNTVDYFDDIMGAIYSKK"
     gene            complement(38128..38694)
                     /locus_tag="VQ862_000117"
     CDS             complement(38128..38694)
                     /locus_tag="VQ862_000117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3114533.1"
                     /translation="MVILELYQNDYSKDLVAFDSIEDGKAFVAQIPGYTLETEDGFEV
                     EYFNPKNIPDYMEIIFNGNIVPLSKFMFDPEENVNIIWKEISNLSLKNDRVIEGYSKI
                     DAYVVNNHEVKAYVETRETNYRKAKDFLESRGYEIDRSFFGSEDGEAILYRKKGIEVW
                     HFLCHLDPMFVEIEDVEGYVKEEVGEIQ"
     gene            complement(38962..40641)
                     /locus_tag="VQ862_000118"
                     /pseudo
     CDS             complement(38962..40641)
                     /locus_tag="VQ862_000118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000031864.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
     gene            complement(40733..40894)
                     /locus_tag="VQ862_000119"
     CDS             complement(40733..40894)
                     /locus_tag="VQ862_000119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005761276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3114534.1"
                     /translation="MDNDWNGLADLIANLIAKYAGALDLDNLPDPTPAKNQEMKNSFD
                     MAKTQIETD"
     gene            complement(41578..41892)
                     /locus_tag="VQ862_000120"
     CDS             complement(41578..41892)
                     /locus_tag="VQ862_000120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001835032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3114535.1"
                     /translation="MGITWKDIEIDKEREGEIDKKSTPIFYGEFKNVRLSKEEYKNLK
                     EKLNSHTDIMINKLSRYMESSGKTYQNHYVTILKWYEEDKDKLRQKGLNKKMNYDVGE
                     SL"
     gene            complement(41858..42247)
                     /locus_tag="VQ862_000121"
     CDS             complement(41858..42247)
                     /locus_tag="VQ862_000121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000690676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HET3114536.1"
                     /translation="MPKRYLLDGKTPRISATNIDNGILGYYEDIDDKNYRVFENFISV
                     SFLGAVFYHKYKASLDMKIHCLKLKNKELNKEVAFYLTSIIRQALKNTEYKDQISSTV
                     LPDIKIKLPIDSRGTPDWNYMERYRDR"
     gene            complement(42635..43429)
                     /locus_tag="VQ862_000122"
     CDS             complement(42635..43429)
                     /locus_tag="VQ862_000122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000677523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3114537.1"
                     /translation="MKGLWSNNLTCGYDEKIILENINIKIPEEKISVIIGSNGCGKST
                     LIKTLSRLIKPLEGEVLLDNKSINSYKEKDLAKHIAILPQSPIIPESITVADLVSRGR
                     FPYRKPFKSLGKDDLEIINRSMVKANVEDLANNLVEELSGGQRQRVWIALALAQDTSI
                     LLLDEPTTYLDISYQIELLDLLTDLNQKYKTTICMILHDINLTARYADYLFAIKEGKL
                     VAEGKPEDILNDKLVKDIFNLEAKIIRDPISNSPLMIPIGKHHVSS"
     gene            complement(43429..44436)
                     /locus_tag="VQ862_000123"
     CDS             complement(43429..44436)
                     /locus_tag="VQ862_000123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001180354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HET3114538.1"
                     /translation="MQNLIIGIQKRKNRITLFSSLFLLIIISLSFFILLIGDESYSFS
                     TLIKVLNSETVPGASFSIMEIRLPKLLAGIIAGWSFGLAGFIFQTMLRNPLASPDIIG
                     VTSSSSIAAVFCILVLKTNSLTTGIISITCGLTSSLILFLLAKKDGFSAARLIILGIG
                     FQAVTRAGTSFLLLKVARYELQEVMRWLSGSLSFTKLDDIPLVLIVSIIATILVLFFN
                     KRLEIIELGEEIAIGLGANPELSRLVLIFCAVSLTAFSTSITGPIACISFLAGPIALN
                     IGKKRSPILAGLVGILLVLLSDIFSQNILPARYPVGVVTGLLGSPYLIYLLIKMNRRN
                     I"
     gene            complement(44436..45443)
                     /locus_tag="VQ862_000124"
     CDS             complement(44436..45443)
                     /locus_tag="VQ862_000124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001244688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HET3114539.1"
                     /translation="MRNKKQINLGIIFVICLGLLITIFLSLKLGTKEINIRDFLAAFG
                     MGNTNDDFIKSIIYKRIPRTIFAILAGSSLAISGVLMQSVTRNPIADPGILGINTGAS
                     LSVVIGLSFLGISSSISHISFAIIGGLVSAIFVYAIAVSGKAGLTPIKLALSGTCVSM
                     ALSSFVSFLILPNNNVLDKFRFWQIGSLGAATLSSISTLLPFIILGHLIAIFISSDLN
                     ALAMGDEMAVGLGVNVNRIRSLAIIASVLLCSSITAIGGPIGFVGLIVPHFCGLFISK
                     DIRTMTISSSFIGAELLLICDIIGRMLGKPGEIEVGIITAIIGGPVLIYVTMKNRGVN
                     N"
     gene            complement(45433..46458)
                     /locus_tag="VQ862_000125"
     CDS             complement(45433..46458)
                     /locus_tag="VQ862_000125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000790748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-siderophore ABC transporter
                     substrate-binding protein"
                     /protein_id="HET3114540.1"
                     /translation="MKNKFFLIAILAMCIVFSACSSNSVKNEENTSKEHAPDKIVLDH
                     AFGQTILDKKPERVATIAWGNHDVALALGIVPVGFSKANYGVSADKGVLPWTEEKIKE
                     LNGKANLFDDLDGLNFEAISNSKPDVILAGYSGITKEDYDTLSKIAPVAAYKSKPWQT
                     LWRDMIKIDSKALGMEKEGDELIKNTEARISKELEKHPEIKGKIKGKKVLFTMINAAD
                     TSKFWIYTSKDPRANYLTDLGLVFPESLKEFESEDSFAKEISAEEANKINDADVIITY
                     GDDKTLEALQKDPLLGKINAIKNGAVAVIPDNTPLAASCTPTPLSINYTIEEYLNLLG
                     NACKNAK"
     gene            complement(46851..47069)
                     /locus_tag="VQ862_000126"
     CDS             complement(46851..47069)
                     /locus_tag="VQ862_000126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001207345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET3114541.1"
                     /translation="MALNYKPLWIQLAKKGLKKTDVIAMAGLTTNVMAQMGKDKPITF
                     KNLERICKALSCTPNDIISFEDNFSDEE"
     gene            complement(47315..47593)
                     /locus_tag="VQ862_000127"
     CDS             complement(47315..47593)
                     /locus_tag="VQ862_000127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000710796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3114542.1"
                     /translation="MKKDKEVYDKVCEYLSPHLNKDMEVLELACWFRVITVIEANSYV
                     NIRSSRLLPKFKTQKINSWYAAYNIHFNNGYCKQHTNEFKDSLKSLIL"
     gene            complement(47807..49438)
                     /gene="rlmD"
                     /locus_tag="VQ862_000128"
     CDS             complement(47807..49438)
                     /gene="rlmD"
                     /locus_tag="VQ862_000128"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000914584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HET3114543.1"
                     /translation="MLKKNDIVEVEIVDLTHEGAGVAKVDGLVFFVENALPSEKILMR
                     VLKVNKKIGFGKVEKYLVQSPHRNQDLDLAYLRSGIADLGHLSYPEQLKFKTKQVKDS
                     LYKIAGIADVEVAETLGMEHPVKYRNKAQVPVRRVNGVLETGFFRKNSHDLMPLEDFF
                     IQDPVIDQVVVALRDLLRRFDLKPYDEKEQSGLIRNLVVRRGHYSGQIMVVLVTTRPK
                     VFRVDQLIEQVIKQFPEIVSVMQNINDQNTNAIFGKEWRTLYGQDYITDQMLGNDFQI
                     AGPAFYQVNTEMAEKLYQTAIDFAELKKDDVVIDAYSGIGTIGLSVAKHVKEVYGVEL
                     IPEAVENSKKNAQLNNISNAHYVCDTAENAMKNWLKDGIQPTVILVDPPRKGLTESFI
                     KASAQTGADRIAYISCNVATMARDIKLYQELGYELKKVQPVDLFPQTHHVETVALLSK
                     LDVDKHISVEIELDEMDLTSAESKATYAQIKEYVWNKFELKVSTLYIAQIKKKCGIEL
                     REHYNKSKKDKQIIPQCTPEKEEAIMDALRHFKMI"
     gene            complement(49512..50486)
                     /locus_tag="VQ862_000129"
     CDS             complement(49512..50486)
                     /locus_tag="VQ862_000129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1002 domain-containing protein"
                     /protein_id="HET3114544.1"
                     /translation="MRKKLFLTSAAVLWAVTAMNSVHAATDVQKVIDETYVQPEYVLG
                     SSLSEDQKNQTLKKLGYNASTDTKELKTMTPDVYSKIMNVANDSSLQLYSSAKIQKLG
                     DKSPLEVKIETPENITKVTQDMYRNAAVTLGMEHAKITVAAPIPVTGESALAGIYYSL
                     EANGAKVPQANKDLAQEELKALSDINAENKDKSGYDANKLNVALADIKSGLAKAKESK
                     GNLTEEDIRKIVEDTLKNYKLDQVITGNQINIIINFALNLSKSDILSNADFTKTLNDL
                     KQSIVSQAGDSFKNINLNFDADKALEDGGNFLSSLWQALVNFFKSFGS"
     gene            complement(50560..51174)
                     /gene="pmp23"
                     /locus_tag="VQ862_000130"
     CDS             complement(50560..51174)
                     /gene="pmp23"
                     /locus_tag="VQ862_000130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000476388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall hydrolase Pmp23"
                     /protein_id="HET3114545.1"
                     /translation="MFKRIRRVLVLAVFLFAGYKAYRVHQDVKQVMTYQPMVREILSE
                     KDTPANEELVLAMIYTETKGKEGDVMQSSESASGSTNTINDNASSIRQGIQTLTGNLY
                     LAQKKGVDIWTAVQAYNFGPAYIDFIAQNGKENTLALAKQYSRETVAPLLGNTTGKTY
                     SYIHPISIFHGAELYVNGGNYYYSRQVRLNLYIIKCFTLFSTSG"
     gene            complement(51174..52148)
                     /locus_tag="VQ862_000131"
     CDS             complement(51174..52148)
                     /locus_tag="VQ862_000131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid-associated protein"
                     /protein_id="HET3114546.1"
                     /translation="MDIYIKKAIIHQFSPDDTELFLADKFLNITPKIEEYLRKKIEHV
                     YSDEAKTGIFEEENPFFNHITDDLLETSVTLANLWKEEFSISENLKTNDLIFVQFSKE
                     GVEHFAFLRIALRETLTHLGGEVDNPIKLTQNNLPGFGTGADEALVVNLQSRKYHLIE
                     KRIKYNGTFLNYFSDNLLAVAPKISPKKSIKELEKTAQRIAESFNTDDFQFQSKVKSA
                     IFNNLEESNELSPEKLANDLFDNNLTARLSFIDQVKEAVPEPVQFDEIDASRQLKKFE
                     NQKLSLSNGIELIVPNNVYQDAESVEFIQNENGTYSILIKNIEDIQSK"
     gene            complement(52156..53412)
                     /locus_tag="VQ862_000132"
     CDS             complement(52156..53412)
                     /locus_tag="VQ862_000132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydroxymethyltransferase"
                     /protein_id="HET3114547.1"
                     /translation="MIFDKDDFKAYDADLWNAIAKEEERQQNNIELIASENVVSKAVM
                     AAQGSILTNKYAEGYPGRRYYGGTDVVDVVETLAIERAKEIFGAKFANVQPHSGSQAN
                     CAAYMSLIEPGDTVMGMDLAAGGHLTHGAPVSFSGQTYNFLSYSVDPETELLDFDAIL
                     KQAQEVKPKLIVAGASAYSQIIDFSKFREIADAVGAKLMVDMAHIAGLVAAGLHPSPV
                     PYAHITTTTTHKTLRGPRGGLILTNDEDLAKKINSAIFPGIQGGPLEHVVAAKAVSFK
                     EVLDPAFKEYAANVIKNSKAMADVFLQDPDFRIISGGTENHLFLVDVTKVVENGKVAQ
                     NLLDEVNITLNKNSIPYETLSPFKTSGIRIGAAAITARGFGEEESRKVAELIIKTLKN
                     SENEAVLEEVRSAVKELTDAFPLYEE"
     gene            complement(53474..53905)
                     /locus_tag="VQ862_000133"
     CDS             complement(53474..53905)
                     /locus_tag="VQ862_000133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000942930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET3114548.1"
                     /translation="MLRDLQETDVKAICDINQEALGYTFSPEETASQLARLSQDSHHF
                     LLGYEDAANHVLLGYVHAEVYESLYSKAGFNILALAVSPQAQGQGIGKSLLQGLEQEA
                     KRCGYGFIRLNSANHRLGAHAFYEKVGYTCDKMQKRFIRIF"
     gene            complement(53907..54506)
                     /locus_tag="VQ862_000134"
     CDS             complement(53907..54506)
                     /locus_tag="VQ862_000134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonylcarbamoyl-AMP synthase"
                     /protein_id="HET3114549.1"
                     /translation="MDRIRQELENGGAVILPTETVYGLFAKALDEKAVDHVYQLKRRP
                     RDKALNLNVASLEDILHFSKNQPAYLQKLVETFLPGPLTIILEANDRVPYWVNSDLAT
                     IGFRMPSHPITLDLIRETGPLIGPSANISGQASGVTFEQILKDFDQEVLGLEDDAFLT
                     GQDSTIVDLSGDKVKILRQGAIKREDILARLPEISFEEA"
     gene            complement(54493..55332)
                     /gene="prmC"
                     /locus_tag="VQ862_000135"
     CDS             complement(54493..55332)
                     /gene="prmC"
                     /locus_tag="VQ862_000135"
                     /EC_number="2.1.1.297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000761890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor N(5)-glutamine
                     methyltransferase"
                     /protein_id="HET3114550.1"
                     /translation="MKLAQLFSNFEEELIRQGEEAESLSFVYRSLKNLSFTDFIFALQ
                     QEVTTEEEKQFVEDIYQQLAAHKPAQYIIGQADFYGMHLKVDERVLIPRPETEELVEL
                     ILTENLETNLSVLDIGTGSGAIALALAKNRPDWSVTAADVSQEALELASENASDQNLN
                     IFFKKSDCFAEISEKYDIIVSNPPYISREDESEVGLNVLHSEPHLALFADEDGLAIYC
                     RIAEDAKDYLKDGGKIYLEIGYKQGQSVPELFRKHLPEKRVRTLKDQFGQDRMVVVDD
                     GQD"
     gene            complement(55332..56411)
                     /gene="prfA"
                     /locus_tag="VQ862_000136"
     CDS             complement(55332..56411)
                     /gene="prfA"
                     /locus_tag="VQ862_000136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002262255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 1"
                     /protein_id="HET3114551.1"
                     /translation="MNIYDQLQAVEDRYEELGELLSDPDVVSDTKRFMELSKEEASNR
                     DTVIAYREYKQVLQNIVDAEEMIKESGGDADLEEMAKQELKDAKAEKEEYEEKLKILL
                     LPKDPNDDKNIILEIRGAAGGDEAALFAGDLLTMYQKYAEAQGWRFEVMEASMNGVGG
                     FKEVVAMVSGQSVYSKLKYESGAHRVQRVPVTESQGRVHTSTATVLVMPEVEEVEYDI
                     DPKDLRVDIYHASGAGGQNVNKVATAVRIVHLPTNIKVEMQEERTQQKNREKAMKIIR
                     ARVADHFAQIAQDEQDAERKSTIGTGDRSERIRTYNFPQNRVTDHRIGLTLQKLDTIL
                     SGKLDEVVDALVLYDQTQKLEELNK"
     gene            complement(56421..56900)
                     /locus_tag="VQ862_000137"
     CDS             complement(56421..56900)
                     /locus_tag="VQ862_000137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET3114552.1"
                     /translation="MTIELRDVTMENYFDVLNLDVKEYQKQFIATNAISLAEAYVYTK
                     NGDFVATLAVYDNDAIIGFVMIAYDKKIGISSGNYLLFRFMIDRNFQNQGYFKPIMDK
                     VLDYVRTAPAGLSNKLWLSYEPENEQARFCYLSYGFKETGEIAENEVVAIYDLTIEK"
     gene            complement(56890..57489)
                     /locus_tag="VQ862_000138"
     CDS             complement(56890..57489)
                     /locus_tag="VQ862_000138"
                     /EC_number="2.7.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidine kinase"
                     /protein_id="HET3114553.1"
                     /translation="MAQLYYRYGTMNSGKTIEILKVAYNYEEQGKGVVIMTSALDTRD
                     GVGYVSSRIGMKRPALAIEETTDIFGYIRDLPEKPYCVLVDEAQFLKRHHVYDLARVV
                     DELDIPVMAFGLKNDFRNELFEGSKYLLLLADKIDEIKTICQYCKKKATMVLRTQDGL
                     PVYDGEQIQIGGNETYISVCRKHYFTPMITSNKEQNYDN"
     gene            57612..57794
                     /locus_tag="VQ862_000139"
     CDS             57612..57794
                     /locus_tag="VQ862_000139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005589823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-oxalocrotonate tautomerase"
                     /protein_id="HET3114554.1"
                     /translation="MPFVRIDLFEGRTLEQKKALAKEVTEAVVRNTGAPQSAVHVIIN
                     DMPEGTYFPQGEMRTK"
     gene            57931..59304
                     /gene="mnmE"
                     /locus_tag="VQ862_000140"
     CDS             57931..59304
                     /gene="mnmE"
                     /locus_tag="VQ862_000140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002906470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis GTPase MnmE"
                     /protein_id="HET3114555.1"
                     /translation="MITREFDTIAAISTPLGEGAIGIVRLSGTDSFAIAQKIFKGKDL
                     NKVASHTLNYGHIIDPLTGKVMDEVMVGAMKSPKTFTREDIIEINTHGGIAVTNEILQ
                     LAIREGARLAEPGEFTKRAFLNGRVDLTQAEAVMDIIRAKTDKAMNIAVKQLDGSLSD
                     LINNTRQEILNTLAQVEVNIDYPEYDDVEEATTAVVREKTMEFEQLLTNLLRTARRGK
                     ILREGISTAIIGRPNVGKSSLLNNLLREDKAIVTDIAGTTRDVIEEYVNINGVPLKLI
                     DTAGIRETDDIVEQIGVERSKKALKEADLVLLVLNASEPLTAQDRQLLEISQDTNRII
                     LLNKTDLPETIETSKLPEDVIRISVLKNQNIDKIEERINNLFFENAGLVEQDATYLSN
                     ARHISLIEKAVESLQAVNQGLELGMPVDLLQVDLTRTWEILGEITGDAAPDELITQLF
                     SQFCLGK"
     gene            complement(59351..60286)
                     /gene="dapA"
                     /locus_tag="VQ862_000141"
     CDS             complement(59351..60286)
                     /gene="dapA"
                     /locus_tag="VQ862_000141"
                     /EC_number="4.3.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate synthase"
                     /protein_id="HET3114556.1"
                     /translation="MSYQDLKECKIITAFITPFHEDGSINFDAIPALIEHLLAHHTDG
                     ILLAGTTAESPTLTHDEELELFAAVQKVVNGRVPLIAGVGTNDTRDSIEFVKEVAEFG
                     GFAAGLAIVPYYNKPSQEGMYQHFKTIADASDLPIIIYNIPGRVVVELTPETMLRLAD
                     HPNIIGVKECTSLANMAYLIEHKPEEFLIYTGEDGDAFHAMNLGADGVISVASHTNGD
                     EMHEMFTAIAESDMKKAAAIQRKFIPKVNALFSYPSPAPVKAILNYMGFEAGPTRLPL
                     VPAPEEDAKRIIKVVVDGDYEATKATVTGVLRPDY"
     gene            complement(60342..61418)
                     /locus_tag="VQ862_000142"
     CDS             complement(60342..61418)
                     /locus_tag="VQ862_000142"
                     /EC_number="1.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000542485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate-semialdehyde dehydrogenase"
                     /protein_id="HET3114557.1"
                     /translation="MGYTVAVVGATGAVGAQMIKMLEESTLPIDKIRYLASARSAGKS
                     LKFKDQDITIEETTETAFEGVDIALFSAGSSTSAKYAPYAVKAGVVVVDNTSYFRQNP
                     DVPLVVPEVNAHALDAHNGIIACPNCSTIQMMVALEPVRQKWGLDRIIVSTYQAVSGA
                     GMGAILETQRELREVLNDGVKPRDLHAEILPSGGDKKHYPIAFNALPQIDVFTDNDYT
                     YEEMKMTKETKKIMEDDSIAVSATCVRIPVLSAHSESVYIETKEVAPIEEVKAAIAAF
                     PGAVLEDDVAHQIYPQAINAVGSRDTFVGRIRKDLDAEKGIHMWVVSDNLLKGAAWNS
                     VQIAETLHERGLVRPTAELKFELK"
     gene            complement(61760..61832)
                     /locus_tag="VQ862_000143"
     tRNA            complement(61760..61832)
                     /locus_tag="VQ862_000143"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(61797..61799),aa:Thr,seq:ggt)
     gene            complement(61932..62441)
                     /locus_tag="VQ862_000144"
     CDS             complement(61932..62441)
                     /locus_tag="VQ862_000144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HET3114558.1"
                     /translation="MKKLTIRDVADIAIVAAIYVVLTVTPPLNAISYGAYQFRISEMM
                     NFMAFYNPKYIIGVTIGCMIANFFSFGLLDVFVGGGSTLVFLSLGVWLFAKYSKDYLF
                     NGLIRKDHFFFSILFSISMFTIAAELNIVAELPFFLTWFTTGIGEFASLIIGAIIIGK
                     IGRRIDLSK"
     regulatory      complement(62439..62535)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01054"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="PreQ1 riboswitch class II; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF01054"
     gene            62564..62995
                     /locus_tag="VQ862_000145"
     CDS             62564..62995
                     /locus_tag="VQ862_000145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GtrA family protein"
                     /protein_id="HET3114559.1"
                     /translation="MKIPIQKFFNNEILAYLFFGLATTLVSILSRLVIYQLSHQELLA
                     TALANIIGILFAFITNDTIVFKQKKKNRLIRLVKFSLARLSTFLLDLFLTFLFVTQFP
                     HIIGQFVTENIDKINAIETIIAQIFIIIINYILSKAYIFRK"
     gene            63077..63454
                     /gene="mscL"
                     /locus_tag="VQ862_000146"
     CDS             63077..63454
                     /gene="mscL"
                     /locus_tag="VQ862_000146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001855364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="large conductance mechanosensitive channel
                     protein MscL"
                     /protein_id="HET3114560.1"
                     /translation="MLKNLKSFLLRGNVIDLAVGVVIASAFGAIVTSLVNDIITPLIL
                     NPALKAAKVERIAQLSWHGVGYGNFLSAIINFIFVGTALFFIIKGIEKAQKLTGIKKE
                     KTAEKKPTELEVLQEIKALLEKK"
     gene            complement(63496..64590)
                     /gene="hemH"
                     /locus_tag="VQ862_000147"
     CDS             complement(63496..64590)
                     /gene="hemH"
                     /locus_tag="VQ862_000147"
                     /EC_number="4.98.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrochelatase"
                     /protein_id="HET3114561.1"
                     /translation="MKKAILMMTFGSPEEITFEGVADFFTNIRRGVRPQDHEIQTLYD
                     NYVRIGGTPLQKITRQEVTLVEARLGNEYSVYFANKFSSPFIPDVIGQMEADGIEQCI
                     CLILEPHYSFYSVMGYEKFLESKQIQFLVIKDWYQEEVLLNYWADEIAKILKEEVKQD
                     SFKVIFSAHSVPIFALDFGDPYIDQIFENSKLVAEKLGLSSEQYTNTWQSESDIGIPW
                     IKPDVLEYLREQTEHPDHYIFVPISFISEHIEVLFDNDVECYDLCQEFGVNYHRSPMP
                     NTDSRLIDALVNTVRVNENQEFKEFLPEEETFDELVPSDETKNILAESEDLQMPEFVK
                     KLIEKKGRENVKMPYLIKKMLEKAGKLPKE"
     gene            64745..65968
                     /gene="pepT"
                     /locus_tag="VQ862_000148"
     CDS             64745..65968
                     /gene="pepT"
                     /locus_tag="VQ862_000148"
                     /EC_number="3.4.11.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000222045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase T"
                     /protein_id="HET3114562.1"
                     /translation="MTYPNLLDRFLTYVKVNTRSDEHSTTTPSTQSQVDFATNVLIPE
                     MKRVGLQNVYYLPNGFAIGTLPANDPSLTRKIGFISHMDTADFNAEGVNPQVIENYDG
                     GVIELGNSGFKLDPADFKSLEKYPGQTLITTDGTTLLGADDKSGIAEIMTAIEYLTAH
                     PEIKHCEIRVGFGPDEEIGVGANKFDAEDFDVDFAYTVDGGPLGELQYETFSAAGAEL
                     HFQGRNVHPGTAKGQMVNALQLAIDFHNQLPENDRPELTEGYQGFYHLMDVTGSVEEA
                     RASYIIRDFEKDAFEARKASMQSIADKMNAELGSYRVTLNLTDQYYNMKEVIEKDMTP
                     ITIAKAVMEDLGITPIIEPIRGGTDGSKISFMGIPTPNIFAGGENMHGRFEYVSLQTM
                     ERAVDTIIGIVAYKG"
     gene            complement(66004..66633)
                     /locus_tag="VQ862_000149"
     CDS             complement(66004..66633)
                     /locus_tag="VQ862_000149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000030436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3114563.1"
                     /translation="MSKVNQLLEQIHEEGIRQSLAEEVENLKAATNKADADLDEVNSQ
                     VKDVLTRIASALQQEKENAEQDSQTLVLYQKLYDILMSLHSYLESNNGSDADFDKVDA
                     LLDQLSAKSKDKTALLESTKAILVLNHQIQSKASASEETSPARNAEANSDNTSAENQP
                     NATAESNIEIASDENKPSNTRDSKPAESTSENETTESSTTTGNQEKPVE"
     gene            66598..66819
                     /locus_tag="VQ862_000150"
     CDS             66598..66819
                     /locus_tag="VQ862_000150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3114564.1"
                     /translation="MDLFQELIYLAQKTFYFFLAICRRLLVAIYHVLLKQESYNPRLQ
                     GLTEIRNPDKTMFVQDAIRFAQQHGFNML"
     gene            complement(67090..68101)
                     /locus_tag="VQ862_000151"
                     /pseudo
     CDS             complement(67090..68101)
                     /locus_tag="VQ862_000151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000669441.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
     gene            complement(68327..71446)
                     /gene="phtE"
                     /locus_tag="VQ862_000152"
     CDS             complement(68327..71446)
                     /gene="phtE"
                     /locus_tag="VQ862_000152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000672589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtE"
                     /protein_id="HET3114565.1"
                     /translation="MKFSKKYIAAGSAVIVSLSLCAYALNQHRSQENKDNNRVSYVDG
                     SQSSQKSENLTPDQVSQKEGIQAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDALFSE
                     ELLMKDPNYQLKDADIVNEVKGGYIIKVDGKYYVYLKDAAHADNVRTKDEINRQKQEH
                     VKDNEKVNSNVAVARSQGRYTTNDGYVFNPADIIEDTGNAYIVPHGGHYHYIPKSDLS
                     ASELAAAKAHLAGKNMQPSQLSYSSTASDNNTQSVAKGSTSKPANKSENLQSLLKELY
                     DSPSAQRYSESDGLVFDPAKIISRTPNGVAIPHGDHYHFIPYSKLSALEEKIARMVPI
                     SGTGSTVSTNAKPNEVVSSLGSLSSNPSSLTTSKKLSSASDGYIFNPKDIVEETATAY
                     IVRHGDHFHYIPKSNQIGQPTLPNNSLATPSPSLPINPGTSHEKHEEDGYGFDANRII
                     AEDESGFVMSHGDHNHYFFKKDLTEEQIKAAQKHLEEVKTSHNGLDSLSSHEQDYPGN
                     AKEMKDLDKKIEEKIAGIMKQYGVKRESIVVNKEKNAIIYPHGDHHHADPIDEHKPVG
                     IGHSHSNYELFKPEEGVAKKEGNKVYTGEELTNVVNLLKNSTFNNQNFTLANGQKRVS
                     FSFPPELEKKLGINMLVKLITPDGKVLEKVSGKVFGEGVGNIANFELDQPYLPGQTFK
                     YTIASKDYPEVSYDGTFTVPTSLAYKMASQTIFYPFHAGDTYLRVNPQFAVPKGTDAL
                     VRVFDEFHGNAYLENNYKVGEIKLPIPKLNQGTTRTAGNKIPVTFMANAYLDNQSTYI
                     VEVPILEKENQTDKPSILPQFKRNKAQENSKLDEKVEEPKTSEKVEKEKLPETGNSTS
                     DSTLEEVPTVDPVQEKVAKFAESYGMKLENVLFNMDGTIELYLPSGEVIKKNMADFTG
                     EAPQGNGENKPSETGKVSTGTVENQPTENKPADSLPEAPNEKPVKPENSTDNGMLNPE
                     GNVGSDPMLDPALEEAPAVDPVQEKLEKFTASYGLGLDSVIFNMDGTIELRLPSGEVI
                     KKNLSDLIA"
     gene            complement(71657..>72421)
                     /gene="phtD"
                     /locus_tag="VQ862_000153"
     CDS             complement(71657..>72421)
                     /gene="phtD"
                     /locus_tag="VQ862_000153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtD"
                     /protein_id="HET3114566.1"
                     /translation="HQDSGNTEAKGAEAIYNRVKAAKKVPLDRVPYNLQYTVEVKNGS
                     LIIPHYDHYHNIKFEWFDEGLYEAPKGYTLEDLLATVKYYVEHPNERPHSDNGFGNAS
                     DHVQRNKNGQADTNQTEKPQTEKPEEDKEHDEVSEPTHPESDEKENHAGLNPSADNLY
                     KPSTDTEETEEEAEDTTDEAEIPQVEHSVINAKIAEAEALLEKVTDSSIRQNAMETLT
                     GLKSSLLLGTKDNNTISAEVDSLLALLKESQPAPIQ"
BASE COUNT        21814 a        14634 c        11546 g        24427 t
ORIGIN      
        1 gatggaactg acgtagtcag tatcctacac gtacggcaag gcgatattga cgtgatttga
       61 agagattttc gaagagtata atctttctcg aatcgctatt gccccttttt tatcccctga
      121 aaccgagtag gagctaagac tagatctctt atctaagtat cggaatacgg ctgttcaact
      181 aaattttagc aagaacttct cccccttctc tcagttcaca gaagcgtttt atacataccg
      241 tcctatcaga caatctattt taaagataac cgtgactcag gatcacttct atctgtcgtt
      301 ttctctttat agtgatagac ctcacgggat aagtcgtaca tctttcctcg tgtatacaag
      361 atataaggac gttaaaaggt tacagtgaaa atagaaaatc ttagtacgaa ttcaattact
      421 ctcgtgattt acgcatatag gttacgacta cctttttgga ctttagagtt tgaggccctc
      481 ttatccgcta tatacgcctt attatcacgt tcctgttcgt agagccacga tttcgctatc
      541 ccttcttctg acaattctta tttccagcgt cagacttaaa acggtctatc cccagaccat
      601 tttaatccgc tacctcacga tagtcaggct tgggaatcgc tatttgactc gccgagaact
      661 ttgacatcag atatactata acaaattgaa ataagaatca aacaatttaa ttttgaaatt
      721 caaatcaatt tataacaata ttttagaaga tatgctgtgc tattccagat tcagtttgct
      781 atacatgcct gtcgtaccac aaaatcccgt gtctgatgag gcacgggatt ttttagcttc
      841 tttactgaga tggattttcc tttttagttc gtgccaatct caaggcacga tttggattga
      901 gacgattaaa tagttcttcc aatttctttt cattccaaac gtctgcggcg gaaacaaaat
      961 taccatccgc atctcggaaa gatatcggtt tatctcccat accagtctcc tagtctacaa
     1021 attcaaactc aaatttacca atgcggacca aatccccatc tttagctcca cgcgcacgaa
     1081 gggcttcatc aacccccata ccacgaagct gacgggcaaa tttcatgaca gattcatcac
     1141 gatcaaagtt ggtcatatta aagagtttca tgagtttttc accagaaagt acccatgtcg
     1201 catcgtcatc acgactaatt tcaaaggctt tttcttcttc gtcaaatcca tagtaagttt
     1261 cttcttccat atcggactcg tcgtagagca aaaattctgg tgtcttgtct aacaattcag
     1321 ctgtagcatc taaaagtgtt gccagacctt gcttggtcaa tccagaaatt gggaagatag
     1381 ctggtaactc ttcaaattca tcataatttt cagccaattt tttcttaaat tcttcaagat
     1441 tttcctgact ctcaggcatg tccatcttat tagctacaat aatctgtgga cgctccatga
     1501 ggcgaagatt gtaagactcc agctctttat tgatagctaa gtaatcctca tatggatcac
     1561 ggccttcgct agctgacata tcaatgatgt gaaggataac acgtgtacgc tcgatgtgac
     1621 ggaggaactg agttcccaaa ccaacacctt gactagcccc ttcaatcaaa cctggcaagt
     1681 cggctactgc aaaggattca cctgattggg tgcgaaccat acctaaattt ggtacaatag
     1741 tggtaaagtg gtaggcacca attttaggct tagctgaggt aataacactt aaaagtgttg
     1801 acttccctac agatgggaat cctactaaac cgacatctgc caagattttt agttccaatt
     1861 gtaactcacg ttcctgacct ggttctccat tttcagagat ttccggtgca ggattttttg
     1921 gtgtcgcgaa acgaatattt ccacgtccac cacgaccacc gtgggcaacg ataaattctt
     1981 gcccatgttc aatcaaatct gttaaaacct tgccagtctc cgcatcacga acagtcgtac
     2041 cttgtggtac tcgaactcta aggtcctcag caccacgacc atgcatccct ttggtcatcc
     2101 ctttttcacc agaatcagcc ttgaaatgac gattgtagcg aaaatccatc aaggtacgta
     2161 gtccttcgtc tacaacgaag accacattgc ctccacgacc accatcacca ccccaagggc
     2221 ctccattagg gacatatttt tcacgacgaa aggcaaccat accatcgcca ccattaccag
     2281 ccttgacctt aatcttagct gtatctaaaa acatactcat tatttcttct cactttaaaa
     2341 aagggctggg aaatcccagt cactaaattt tcttgaatct attttataga ttactgaggg
     2401 caccaattgc agttgcaaaa attcccaata aacttgctac tagcatgata atcacgataa
     2461 acaaggttat tttctcaaac atagtttttt tacgatttcc attatctcca aatgccattt
     2521 ttctctcctt cgttacattc tattttctat tatcttagca tgaattgagc tagttttcaa
     2581 tagtcagttg ctactggtgc gataatccat aaaataatgt aagctacaat tccagctccg
     2641 taacagcaag taagaacacc ccaaatgact tgaacgatag tcggatccat atccagataa
     2701 tgggccaccc cagcacaaac acccgcaatc tttttatcac gaccgcttct cattaattgt
     2761 ttttttcata gctgttcctc tttctattct tcatggtctt tccaatagtc tctcatactg
     2821 atcaactgtg tttttgaagc cttcaacatg cgtctagatc cttttacagg tacagcaacc
     2881 acctgttgcg gaagatacaa aactgtctta aagatacgct gactgaccgt atcatcttta
     2941 gccaaatctt tctggaagtt atttgaaata atggcatcca gataaaactc atgcactcgt
     3001 ttcccaaagt tctcagctga aatctcatac aatttctctg ataaggtatg ctcattcatg
     3061 tctggtgttg caatcagggc ttccgaaata gcaccagcca aatcatgttc tccatagtac
     3121 aaggttccaa acattttatc actgatgagg ttgttcaaat aaggatttcc gtgagcaatg
     3181 acaggtgttc cactggctaa gctttccaag taggtcaaac cttgcgtttc gcttgtcgat
     3241 gccgaaatga agaaatccgc cgctttatag taaagagccg tctcactagg agcaatcatc
     3301 cctgtaaaga tgactgagtc ttgaatctct aggttctggg cttgctcttt gaggtcattc
     3361 agataagggc catccccagc tactaccagt ttaaccttgt cttcctcttt cagaacatca
     3421 gcaaaggcta ctaaaactgc ttgaatattt ttttcatagg agattctcga aagactaagc
     3481 aacgtctttt caccatcttg aatccctagt ttactacgca gttctttcaa attttcctgc
     3541 ttgatttccg gacgctcaaa cttggctaat tcaattccag taggaatgac ccgtttttca
     3601 accttgacct tataatcaga tagcaagtca cggacaatct cactagggca aataacccca
     3661 tccacatcat gcaggaaacc tctaaccaga tacttgacca tactcggccg gatcaacatc
     3721 cccttagcaa tataatggac atagtcttca tactgggtgt gataggtatg gatgactgga
     3781 attttcaatt cacgcgcaat ccaaatcccc aacaggccaa gagaaaattc tgtctgagta
     3841 tggataatat ctagctgata ctgtttagca atttcaagtg ccttgctaaa acctcggtag
     3901 gcaaagcgac gatccttaaa agcaaagaaa ggaacacttg gaatgcggat aatttgccaa
     3961 tcttcgtagc gattgacatc cttatctgtc gtcgtaaaga taaaaacagc atgtccctgc
     4021 ttttcaagtt ctgttttcaa ggttcgaata ctggtcgcaa caccagaaac ctgaggaaaa
     4081 taggtatctg taaataaacc aattcgcata gattacctca ctttttactt tctccctaaa
     4141 gcggcttgtt tctcataaaa gtccaaccag atttgtaaca gatgctcttc agaatactct
     4201 ctggaaatat tcttagcctt ttctttgaga tcttttaagg tagcaggatt tgcttgatat
     4261 tccaaaatag cctctttcat ctcttctcta cccgctgtcg cccgataatt tccctccaaa
     4321 atcaccttat agagatctaa atcacgcaac ataataggag cctcacaact cgcagcttct
     4381 aaaatagtca taggaaagag ctcattgtaa ctaggcaaca agaaaagatc cgctagagca
     4441 tacaattcgc gcatccgctc tggcgataca atgcctggaa aaatcaaatt tttaggggga
     4501 ttttccataa ttttcttata gtgttcataa ccatctgtca taccaccaaa agagaagcca
     4561 ccagcccaga taaaggtaat ctgaggcaat tcctcagcca gacggataaa gtcatcaatc
     4621 cctttacgtt tctgaacttg cccagcacct actacgataa actgattgtc actaagacca
     4681 agatctgtgc gcagtctaac tacctcttct tgtggtagag gatgccattt ttccttgttg
     4741 acaaagttag gaatataggt cactttttca cgtggaatac cagctgctac caaatcctca
     4801 ataaacatag gattgaccac aaccaagtgc tccatccggt tgtaaaaaga aaatacatag
     4861 cgtttcacaa ttccctttaa gaaaaatgga attttcaaac ttccctcaag tgtagctggc
     4921 aagaaatgca catagccaat ctttctccct gagcgtttct tttggaaggt tgataaataa
     4981 tagggaaaat caatcgtatg aaagtgagtc acatctgcct cgattggaag attttctgta
     5041 acaatcaatt ggtccttggc agcacggtga agaagacgaa ctaattcacg gtaagcacct
     5101 gaaactccct gtcctgctac tttctcactt gaactcaaca tattgatgcg taatttcttt
     5161 ttctccataa ctactattat atcattttct ttgaataaaa tcagcaaaag aaaggagaga
     5221 ctagaggaaa agaggggaaa tttcctcgct tttccaacag tctctcacat gcttttatat
     5281 gtttacttaa tgcctagggc aatgcgggca tagcgactca ttttttcaac tgtccaggct
     5341 ggataccaga ctaatttaac ctcagtatcc gttacttctg gaacctctat catagcatca
     5401 taaatctggt ctgtcaaaag gtctgctaag ggacaaccca tagttgtcaa agtcatgtca
     5461 atctctgttt gccctgtgtc accgtcaaaa cgaatctcat agatcaaacc aagattgaca
     5521 atatcgattc ccaactcagg gtcgatgact tcttccaagg ctgttaaaat ccgtgttttg
     5581 atgttttcaa tttgctcttc tgtataagcc atattttcct cactcttagt cttcaataaa
     5641 atcacgaagc ggtttgctac gacttggttg gcgtagtttt ctcaaagcct ttgcttcaat
     5701 ctgacggata cgctcacgag ttacgttaaa gactttcccc acatcttcaa gtgtgcgcat
     5761 ttttccatca tctagtccaa aacgtagacg cagaacattt tcttcacggt ctgtaagagt
     5821 atctaagatt tcatccaatt gctcacgcaa gacgatacga gtcgtataat ccactggatt
     5881 ttcaatcact tcatcttcga taaagtctcc gaggtggcta tcgtcctctt caccgatagg
     5941 agtttcaaga gatactggtt cttgggcaat cttcaagatt tcacgaacct tatcaggtgt
     6001 catatccatt cgttcagcaa tctgttctgg tgtcggatct tgccccaatt cttgaaggag
     6061 attccgctgt tcacgaacca atttattgat agtttcaacc atgtgaactg ggatacggat
     6121 ggtacgagct tggtccgcaa tagcacgagt gatagcctga cgaatccacc aagttgcata
     6181 agttgaaaac ttgaaccctt tagaatagtc aaacttgtca accgccttca tcaagcccat
     6241 atttccttct tgaatcaagt caaggaactg cataccacga ccgacatagc gtttggcaat
     6301 ggaaacaacc aaacgaagat tggcttccgc aagacgttgt ttggcttcga tatcaccagc
     6361 ttcaacagcc agtgccaact ctttctcctc ttcattggtc aagagaggaa cgacccctat
     6421 ttctttcaag tacatacgga cagggtcatt gaccttagca gaagttgacc caatcaagtc
     6481 ctcatcgctg agttctggtt cttcttcatt gctaagaaca cgcgcacttg gatttccttc
     6541 gttatctgtg atagaaattc ctgcatcctg aatccgttgc aagagatctt caatcccatc
     6601 agcgtccaag gtaaaaggaa taaccaaact tgcattgatt tcatcatctg ttgctgtccc
     6661 tttttgctta tgattacgga taaattctgc tacctgtacg tcaaatgttg ttacttcttt
     6721 ttgttttgtt gccattatta ctccattctt ctcttttggg aaattaaacg ttccaattct
     6781 tctagggctg tatctgtatc tcctacatgg ctagcttcct gcaccttctt tttgattctc
     6841 atattgtcct gattcaagag agccttgttt cgagtcatct ctacttcact aagttcctgc
     6901 ggcgatatct cagcaggcaa atcctgagct aaaacttggt accaagctct ttcaacttcc
     6961 tctgtctgct ctgctaaaac ttctggagga agatttccat actggccaag caagtcatat
     7021 aagacctgaa attcaggtgt agcaaatgca aagtcttctc gcaaacggta atcgttcaaa
     7081 acaagagggg attccatcat ccgatagagt agatgggctt ctgccctcat aatagccgat
     7141 aactgcttgg tgacaggcat ggtgattggc gtcggtctgg aaattctttc catgcgattc
     7201 tgcctttgca cctgacgact ctcattaaca atctgctcaa tctgggcata atcaaaggac
     7261 gccagactgt cagctaaaat atgaatatag ctgttttgag cagcgatgga cttttcttta
     7321 acaatcaagg gagctatttt ttcaataaac tcaatctgag cctgcagatt ttcactgttt
     7381 tcaggtttgt actgatgaat gtagaactca atcggactaa tacgagtttt cgttaataga
     7441 taggccaagt cttctggacc atttttttgt agatactcat caggatccaa gttatcaggc
     7501 atgctgacga tttgcacagg catatcacca atttcatcca atgctttcaa tatcgcggct
     7561 tgcccagcct tatctccatc gtaaacaaga accaatttct tggttaacct tttcagatgc
     7621 tcaacatgct ctcgactcaa ggccgttccc atcgacgcca cagcattttc gattccaacc
     7681 cgataggctg caataacatc catgaatcct tccatcaggt aaatctcact agcttttcca
     7741 gaagattttt ttgccctatc catatgatat aattcgtaac ttttgttaaa aattgcagtc
     7801 gatcggctgt ttttatactt agaagtttgt gaatccgttt tttgccagat acgacctgag
     7861 aaggcaatga tctttccttg gtcatttgtc aggggaaaca taatgcgatt gtgaaaggtg
     7921 tctacaaatt gattggcatc cgagagataa aacaggcctg aatccagtaa atcctcttca
     7981 cgatactgat cagacaaacg ttgatagaga tagtttcgtt ctggaggtgc taaaccaatc
     8041 caaaaatgtt taagcacttc atctgtcaaa ccccgctgat aaaggtaatt tctggcctct
     8101 tctcccatag tcgttgtcat gagaatagca tggtaaaatt tggctgcatc ttcgtgcata
     8161 tcataaagag cttggtgagg tgaggctgac ttctgctcac tataaagcgg tttttcaacc
     8221 tcaattccaa cacgctgacc taagatttgg actgcctcta taaagggaac cccttggtac
     8281 tcctcgatga acttaaagac atcacctgag cgaccacaac cgaaacagtg ataaaactgc
     8341 ttatcctcta caacgttgaa agatggtgtt ttttcgccat gaaaaggaca gagccctaga
     8401 tagttccgtc ctgccttttg taaagaaatc acatctccta tgacttccac aatgttggct
     8461 ttgtttttga tttcttcaat gacttgtttg tcaaccatac acaatacctc catgttatca
     8521 tagtatacta tatatagtat actttatttc agaaaaaaag taaactattt cactcatttt
     8581 ccctacttta ttcaaagagt tgataataat cagagatttt catttttgct ttttcttctt
     8641 ggtttaaatc ttggataatc cgtccttctt tcatgacaat caagcgattg ccgtatttga
     8701 gagcatcttc catatgatga gtaatcataa gggctgttag ctgatctttc ttaacaaatt
     8761 catctgtcaa ttccatcaaa gcaacactag tctttggatc cagggcagca gtatgctcat
     8821 ctaacaggag taattcaggt cgcttcaagg ttgccatcaa gagactcaaa gcctgtcttt
     8881 gtccacctga taagaactca atcggtgtat tcaagtgttt ctcaagacca tttcctactt
     8941 tttcaatggt tacctgaaat tcatccttat agctagtcaa gcgtcgtggt aacaatccac
     9001 gcttttcacc acgaaacttg gcgattaaaa gattttcagc gaccgtcata cggggagctg
     9061 tccccatctt tggatcttgg aagacacgag acaggtactt ggcacgcttc tcgggtgaaa
     9121 acttagtgag atcttcacct aaaatacgga tagttccact agttagtgat aaggtccctg
     9181 ctatagtgtt aaagagggtt gattttccag caccatttcc gcccaaaatc gtgataaagt
     9241 cccgttcaaa aatttctaag gaaacatcat ttaaaataat cttttcttca tcaaagccat
     9301 ttttaacgat tttggttgca ttttttaatt ctacaattgc tgtcatttgc ttaacttggc
     9361 tcctttcaag attgtttgct taaatgttgg aatcatgagg cagactgcta aaatcaaggc
     9421 actgtataaa cgaaggtaac ttgtattaaa gccaagtgcg ataactgccc acactaaaaa
     9481 ttgataagcg atagaaccta caacgatagt aaccaaacgc tctgccaagc tcaaactctt
     9541 gaaaataact tctccaataa tcaaacttgc aagccccaca acgataaccc cgatccctcg
     9601 agacacatcg gcataacctt cttgctgagc aatgagggca cctgcaaggg caatcacacc
     9661 atttgataag accaagccca tgagctccat gcgtccagta tgaatcccga aacttctagc
     9721 catatcagga ttatcccctg tagcaatata ggcttgtccg agtttagtgt ccaagaaaaa
     9781 gagcatgaga gcaataacaa tactcacaaa gatgagacct gtcaagagtt gattcaaatc
     9841 cgaatcaaaa ggcaaaacat cctgaatttg cttggttcca agcaggccta aattcgcacg
     9901 tcccataatc aagagcatga ttgagtgaca agaagtcatc accaaaatcc ctgagagcaa
     9961 ggttgggatc ttcccttttg tataaagaag gcctgctgcc attccagcca aacaacctgc
    10021 tcctacagca acaagtgtcg ctaaaaatgg gttcacgcct ttggttatca aagtgacagc
    10081 aacagctccc ccaagaggga aggaaccttc tgtcgtcata tctggaaagt ttaaaatcct
    10141 aaatgtcata aagattccca gacctagaat agcccagaca aatccttgag aaataatgga
    10201 aacaatcata ttttatttaa tcctttctat attcatcttt ttaaaaaatg ggaagagtct
    10261 cctcctccct accttattta ttcgatgact tgtcctgctt ctttgagaac agactcaggg
    10321 atagtaatac ctagttcttg tgctattttt ttattgatga ctgacttacc agttgaaaag
    10381 acattgactg gggtatcggc tggttttgca cctttcaaga cttgcacaat cattttacct
    10441 gttgccacac caaggtcatg ttggtcaatt acaactgatg ccaaaccacc tacttctacc
    10501 atagctgtcg cactgggata aattggtttc ttagaacttt gattgctaga gacaaccgtt
    10561 ggaaatcctg atgcaatggt gttatcaatt ggaacccaaa tagcatctac cttgctagtc
    10621 ataacagtga cagttgaggc aatttcattt gttgaaggaa ctgcaaatgt ttccactgtc
    10681 agacctgctt tttcagcata agccttaaat tcttcgacct gtgtttttga attgtcttcg
    10741 ctacttgagt aaagagctcc gattgttttc acattcggtg tcagagcctt gatgagttca
    10801 acttgttgtt gagctggatt gtggtcagat acccctgtaa tgttgccacc tggttttttc
    10861 aaatctttaa ccaagttagc accaattggg tctgtaatag cggccatgat aaccggtagg
    10921 tcttttgttg cactagccaa cccttgggct gctggtgttg cgataccaac cacaaggtca
    10981 ttcccatttg caaccaattg tttactcatt gtcgcaacct tactttggtc accttctgag
    11041 ttcataaaat caattttaac ttgatcatct ttatatcctt cttctgcaag tccatcttgg
    11101 atccctttat aaatcaaatc aagggatgga tggctcacaa attgaagcac accaatctta
    11161 gttattttct tctcatcctt attattctga gcttctgatt tattcattga agaataaatc
    11221 aagcttcctg ctactaagac tgctaatgca gcaataattc caattaaacg tttatttttc
    11281 attctgtttc tcctttttat ttcctttaac atatttcact tatctaaaca agcgacgcca
    11341 tcgttttctt tccatactaa cctccatcaa aaaaatcctc acacaaaaaa cttgtgtgag
    11401 gacgtcgatg cgcggtacca cctcaattat agggaatttc cctatcgctc agtctcgcaa
    11461 taacgagatg cactgtaagg tgtgcttacc gaatttttat aatttcaaat tctaaatagc
    11521 attcagccca attttcatca tcgccactta tctgttttca gctaccacag actctctaaa
    11581 aagtttgtat gattactttt ctgaatggtt aaattatatc atttttaaac tacttgtcaa
    11641 tagtctatta gaattttttt gatattcact tttagcattc actcttgaaa attatcaacc
    11701 tgaattacgc aatcctgtcg caattccgtt gatggtgata tgaatcaatc gttcttgatc
    11761 actggacaat tctccacgac gttggcgttt aatcaactct aactgaatat agttgagaat
    11821 attaaagtaa ggcatacggt aatccagact agcttttaga tatggattgt cagctaagag
    11881 ttcgtcatgt ccttcaatag ccaagataac gttcttagta acttgccatt catttaaaat
    11941 aatctcatag atggccttaa cttgctcgtc ttcacaaagt ttagcatatt caaaagcaat
    12001 attcatattt gattttgaca aaaccatatc aacatttgaa agaagcgatt ggaagaaagg
    12061 ccaattttgg tacatatctc gtaagatagc aatattctct ggatttttat tgataaattc
    12121 cttgaagctt gaaccaaccc cgtaccatcc agggaacata acacgactct gtgaccatga
    12181 gaatacccaa gggatggcac gcaaaccacc gatttcagta atagtcttac gagcggctgg
    12241 acgagaacca atattaaaac ttgaaatagc cttgattgga cttgactcga agaaataatc
    12301 atagaaatgc tcattaccaa agaccaaatc acggtagata tcgtaactac ggtccactac
    12361 ttgatccata atggcttcat aacgatttgg ggtattggta tcgctcttct tctgagtaat
    12421 catacggtta atagctgccg atactagcat ttcaaggtta tagtaagcgg cgtctttgtt
    12481 accgtattta ttcccaatta cttcaccctg ctccgtcaaa cggatacgat ccttgataga
    12541 cttgagcggt tgagatgtaa tggcttcata ggttggccca ccaccacgac cgacagtacc
    12601 accacgacca tggaagaagg taaccttaac gccaaattca tctccaatag cagtcaattg
    12661 ttgttgagcc ttgtagaggg tccaacatga tgacaagtaa ccgccatctt tattactgtc
    12721 agagtagcca agcatgattt cttggtagtt atttcgtgag tcaatccatt ttttggcaag
    12781 gctaagagaa agatattttc tcattgtttc ctctgaatga tccaagtctt caattgtttc
    12841 aaaaagggga acaatctgaa cacgcgccct ttccgtatcc accagtccta cttcttttaa
    12901 cagaatagct aattctagca tatcagaaag gttggttgca tgtgaaatga tggtctgacg
    12961 gatgacatca tctcccaact tatctttcaa aacacgagcc gtcttaaaaa tagctaattc
    13021 ttttgctaat aattctgatt tttctgcgtg agtcgcagaa agaattcggg gatcttcttc
    13081 taattctttc aagagaaggt cacacttttc ttcttcgctc aactcgctat aacgagaatg
    13141 aattcctgct gatttcaaga gttctgccac acaggcttca tagacgctag agtcttgtcg
    13201 catatcaatt gatgctaagt aaaaaccaaa tatctctact gcctgcaata attccacaaa
    13261 atcacctgaa atcaaggact cgcccttatt ttctagtaga gaatctcgaa tggcaatcaa
    13321 atccttgtag aaatcattgg cggtttcata acgagtccca acttcttcat cctcaatcag
    13381 ataggtttta gttgcctgaa tttttgattg aatatcaaac aaggcacgac ggtaaagctc
    13441 tttttcgcgg taaatcgagt tatccttgga ttgacgagcc atttctctga cttgcttgct
    13501 gacgttgaca atgctagttg aaagagaaaa ttcacgataa agttggtaaa tctttttatc
    13561 atagtagttc atgatgactt cacactgagt gagtgcagac tgcttcaagg tctttgctgt
    13621 aacaaatgga tttccatcac ggtcaccacc tatccacata cccatggtga ttggtttagc
    13681 ctgttttaaa ttcagaccat gcgcttgcgc taagcgctta tactccgtcg tcaaatgagg
    13741 tacagctttc aaaaaggagc tgttataata ttccatagca ttcgtgattt cgttagtcac
    13801 ttttaatttt ttctcacgaa tcatgtctgt ctgcatgata atttcgatgt aacgacgcaa
    13861 atcattgtac catttatctt tattgatcaa ccccaactta acatcacggt atttacgcaa
    13921 aagactatga atatgatttg ttaaatccaa catacttttg cgttgcactt gtgttggatg
    13981 ggctgtcaaa acagggacaa cattcaagtg ttctaggatc tcaacggcat tttccttttc
    14041 tgctaccaat ttaatcgttg tagataattt acctaaatag tcctgatcaa tattattttg
    14101 atgattgatt tcataagcta aatccacatc ctctgaaata ttaatcaaaa gaggcaagat
    14161 agagaaatag cgtgaaatat agaccatttc atcatttgat aagctagtca ctagacggtt
    14221 tagaccttga taatcttcct gcgttgataa ttctttcaac tgtattattt tttcaaaggt
    14281 ctctggggca agcatatttt tagtaatatc ttccagtaat tctgttagaa taaagacttc
    14341 ttcttgcaca acacttttat tactataatt ttctaatttt tgaagagaca taaactatcc
    14401 tttctttatc ctacttcaac agaaggttca ttggttgatt ttccaattct cggtacaatt
    14461 tagcgcgttt ttcactggca tcaatattta agacaaaggc tactgccact gataagacta
    14521 gaagactatt tccaccctgg gataagaagg ggaaagtcac tcctgtagat ggaatcaagc
    14581 ccgaaatccc tccgatattg acaaatacct gaaccaacat catccctccg acaccgagtg
    14641 caaccatggc attgaaagga ttctccgctc ggataccgac caagataatc cgcaaaatca
    14701 tgaaaaacaa gagagctaaa ataagactgg caccaacaaa gccaaattct tcaatcacga
    14761 tagaaaagac aaagtctgta tgagcttctg gcaaataacc tcgtttttca atcgagtttc
    14821 caagacctag accaaaccaa ccgccattga ccatggcaaa ataagaatta gctaactggt
    14881 gacctgcatc agcacgatcg gcaaaaggat taaaaaaggc actaaagcgc ttggctacat
    14941 agccaaatac tggaattttt gaaaaggtct caacaccgat taggctgata gtggtcaaga
    15001 caaagacaga agtggcagat acgagcgcca gaatggttga aaaccagcga taagcgattc
    15061 cactaactgt atacataatc aaggaaacca agactaaaat agtcgcattt cctaaatcag
    15121 ggaaaattcc caaacttcca atcagaacta ggagaacgaa tcgccaatca ttaaaagcac
    15181 ggggaagcca ttgattttga gtcaaaactt gaaaatcata agtagctatt tcttcttgct
    15241 gtttggagaa tcggtgagct aaataccaaa taataatgat ttttaagtac tcagctggct
    15301 gaatagttac tcctgcaacc gaaatccaac cgtatgcccc gtttactgaa ataccaataa
    15361 aacgagccaa gaacaataaa agcatttcta ttaatataac taaaatgatt agtcgctcat
    15421 ttctcaaaaa atctagtctc aatttataaa ttaaggcaat cagtatcaaa ctaacaatcc
    15481 aaaagattcc ttggtttcga accaactgca aggcgctctt gccttcttca attaaaatag
    15541 cactggtggt cgaatagacc acaatcaagc ccaaaataga taaaagcaag tagggaatca
    15601 agatggaata atttaataag tgcctcttac taatcttcat agtatcacca ctctactagg
    15661 atacagacaa atctgttcca aattccgttt tattttctag ttttgattgc tattatacca
    15721 ttttttcaga aagaaaaaaa ctcttacctt acaatccttc gaattttact gtttttacag
    15781 aattaaggca gaatttgaaa tcgtaaaacc attttgaata agagttgctt caatccattg
    15841 actccgacta attatgttgc tttcgtgaat gccaaaatca gccgcaattt gttcataagt
    15901 gcgctattct cgcatgtatt gaatagttac cataaggaga tcgtctaggc ttaatttgct
    15961 ttttcgtcca ccttttgcgc gtttacgttg ataagctgtt tttaacaccg ctaacatctc
    16021 ttcaaaagtc gtgcgctgaa cacctacaag gatcttgaaa cggctatcgc tcaattgttt
    16081 acttgcttca tcattcatag ttttattgta ttatattttt gtttcgcagg aagtctatta
    16141 ttcctttcgt tccaaggttt ttacgctttt agcaacaagc ttacacactc cacgtgatgc
    16201 gtctgtagaa ctcaaaaggt tcggggaacc ttttgaggat taattgcgtt tatctaacaa
    16261 actcacacat tcaacatggc atgactgatg aagtcatcat aagaatttca cttgctgctc
    16321 ttttacggtg gcagcctgaa cggtcagaag tatcattgta tatcatttgt atcatggcat
    16381 ataaagtatc gctctatttt attgatggtt ttaatatcgc tcttatcatg gcgaaccatt
    16441 caaatctgct ccacaaatga ggaaagtacc attttggact attcaattgt caaagaacaa
    16501 ataaaaaaaa tcttcgcatt ttcacactct atgaaattga ggagattatt ttctaaagcg
    16561 aattttatca ggaaaatccg tcaatcccaa taggtagtct gtactgacat cgtaaaagtt
    16621 tgagagagtt accaatatat ctgctgttaa cgtatgctca ccccgttcaa ttttagcata
    16681 agctgagtct gtaaacgaaa gtattttagc tatttgtttt tgggtcaaat cgtgatcttc
    16741 cctcaaatct ctcaaacgtc tgtacatcta gctttctcct gagaaaagta taatatataa
    16801 aactaagaaa tcattcaaag tgtccaaact ggacattttg aactaaaatt aatttattaa
    16861 acatatctca taagcatatc tattataggt aagacaatat taagaaagac ggtcaaaatc
    16921 tattaaccgt ctaaagatgt tataagctat taaaaaatca gcagtaatcc ggtaacaaaa
    16981 gtcacataat tttgttaagg aagggattaa tgatgtccag attactacta accagcaaat
    17041 tgaaaaatgg tcaacatgat atttctaatg tgaatctctt actttcagaa cctaaaagct
    17101 gaataatagc caccccctac ttatcaataa aattttccgt tgcattaaca gatgtatata
    17161 gaccactcca tggatttcaa agcaattaac tagactttat ttgtcaataa ccacaaaatt
    17221 agattagaaa aatcattaaa aattaattgg agtcctttgt gatgcttttt caataaaagt
    17281 aatacttctc aatattttaa ctgaactaaa gaaatagcat aatggtatct tgattgtatt
    17341 cttctaaaaa ggattgccct tcacattcaa ctgtgattga ttaaattcca aaaatatatt
    17401 ccaaaggcgc tctaaattct ctatatcagc tattttttat catctatcaa cttctatcat
    17461 acctcttcaa tagcgtgcta aatattagcg ataatatcgt aatagataca ccaataataa
    17521 aaaaattaaa agtattgtta ggatttaaaa ctactgagaa aaaaacagta cctagtggca
    17581 taaaaagaat agctaccgta aagatgattc caaatactct gccaagaaac tcattatcta
    17641 cgtctctttg aacaatagag aaaaattgga tattaaaaat ggaaagaaat agactaaata
    17701 atgctggagt aaaggctaaa ataatgacgt tgcggaacat ataatagatc ggcgctgtta
    17761 gcattaacat caaacctgaa tatgctaaaa agagcattaa acgtttgctt gacaaggatt
    17821 tattgataaa tccacttaat atcgcaccaa taaagccacc aatcgcttcg gctgttaaaa
    17881 aggttccata tagcccactt gaaatacttc caaacatttg attactgtat ggcagcaaca
    17941 aattataggc tgctaggaaa aagttaacaa gtgctgaaag ggcaattata gtgagaattt
    18001 gtttatgact atatacatac gtaaatccta tttttaaatc atcaaagatt cctcttatcg
    18061 tcatattctc ttttgtatcc acctcctcat ttacaggagt aatgaagaaa attagtgagg
    18121 cagcaattaa aaacgataat ccatctagta ataacacacc atgtattcca agtaacttat
    18181 ataagaaaat tgcaatcata ggaattgtta ctttaatcac agtacttgtt gtttctagca
    18241 atgaattaag ttatgatata ctgtcctttt ttacaatttc tttcgtaaaa gctttgtatg
    18301 atggccctga aaaagcactc ataaaagcca aaatgacatt tgttatgact atcgcataaa
    18361 ccaaccattt ttcttgggat ataaatgaaa gagttatgca agcaatacca cataagatat
    18421 ttgtagtaat aataattttt ttccgcttga aactatctgc aataactcca ccaaataaat
    18481 taaatagaac acctatcata ctttctaatg attgataaat tgcaaccact gatagagatg
    18541 ttggattaag accagcaaga aaggtattat tggcgaaatc aaacatgata tctccgattc
    18601 gagatatcat cctactagct acaatggata gaatattgtg atgttcttct ctaatcattt
    18661 tattctcccg aatcagtaat cacatattta aacttttgtg atatgtgctt aagttcatct
    18721 aaccttttct caaattcaca actatttttg caattaaatt ggacaaacat tgaattttcg
    18781 actacatttt cagatacttt atagtaagta tttggtttaa taaatatgta cacttttttt
    18841 gcccaagcca attctttttc atcaggtacc tcgataacct taccttgctt tctatataaa
    18901 gcaaacgttg ctgagatatt agcaggtcta gaaatcactt tagaaaaatt tatttttttc
    18961 aatacttgtg aattagtcaa aatatcccaa tattctttaa ttacatcaac tccatgacta
    19021 tcctcaatta actggggaat atctccccct ccaaatcttt ttccaacttc acaaaagact
    19081 attttaccag ttgataattc aaggaaccat tcaaaatgaa aaggggttat ttcagaattg
    19141 atagaaaaaa cattcaaaac tttgcgacat tcttccaatg ctttttctat gtattcaatt
    19201 ttttcactat cattatataa cgaactagtc cttacaagat aatatccact agaacttaag
    19261 gtattgaaca atagttcctc atattcgtga acataaaatc gcttaatctc acttccaatt
    19321 gaataaccat cacatgttat catgttatcg atatcaatgt attcctctat aatatagttt
    19381 ttttcaaaat acactgaatc aattttctcg ttagggtaaa ctttttttat tccattactt
    19441 cctgcttcat ttctaggttt taaaattgca gcagaagatt tacaattatt ccaaaaaaca
    19501 cgtaaatcat tttctgattc taaaagccta aaatacggtt gatttactac tccaactaaa
    19561 aatgaacgca tgaagtattt gtctttaaat aataaattag acacagagtg agtatttttt
    19621 tctacaaaat gatcattcaa aaaacctact atatccatgt cttcctcact caaggttgta
    19681 atactctcaa cttctgtatt ttgacttatc cttctaattt ctaagatgat atttggtaga
    19741 ataaaatctt ctaaaaaaat gaccttaggt agattatttc cttcagctag ataatcttca
    19801 tatttttttc tttgaacctc aggtgcaata attactacat ttctgttata cagatatttt
    19861 agtttaacaa cccgtgcaga atatctaaat aatactatat gcatgttaat cccaatcctt
    19921 tcaattatta gtcatcatat ccatttggat gtttctgttg ccatttccac gtatcttggc
    19981 acattttcat aatatcatac cttggcttcc atcccagtag ctcttctgct tttgaaatat
    20041 ctgcaattga aacgtccata tctcctgctc tccttgaagt tatcttatat ggaatatacg
    20101 agcctatgac actctctaag ctgtgtagga tttcaaatac actaaaacca acaccacttc
    20161 ctaaattgat tacttcatat aaaccttcat ctgtattaaa aatatactct aatgcttttc
    20221 tgtgtccgtc tgctaaatcg ttaacgtgaa catagtccct tatacaagtc ccatcaggag
    20281 tactgtaatc aactccgaat atatttaaat atggtaattt tccaattgca acttgtgtaa
    20341 tgtaaggaac aagattattc ggaattccat ttggatcctc tcctaaatca ccactttcat
    20401 gtgcacccaa tggattaaaa tacctcagac aaacaatttt ccaatttgaa ttcgaaataa
    20461 acaaatcatt taaaagtact tctatatact gttttgttct cccatacggg tttgaagctt
    20521 ttaatggatt agtctcatag aatggcatga taggagtact ttcgtataca gtagctgatg
    20581 aactaaacac aaaattaaat accttatatt ttttcattag ttttaaaata tttatagttg
    20641 ataataaatt attttcataa tacttcaatg gttcaaccac ggattctcca acagctttat
    20701 accctgcaaa atgaattact ccatcaaaat tatgtctctt aaaaacattt tccaattttt
    20761 cttcattttt taaatcaatt ttataaaaat gaagatttct actcttcttg gatatctgct
    20821 taatagactc aataactttt ttcttagagt tactcaaatc atcaatgatt gttacttcat
    20881 aattattatc taacaagtcc aaaaccgtat gtgatcctat gtatcctgct ccacctgtta
    20941 ttaataatga tttcatgcta atttacctcc atattcttta tgccattaat ttgaaattta
    21001 tcttggctaa aaattaccct atttgatttt gcttcacttc caagaaagtt accgatagaa
    21061 atttctggaa attcaaaaat ctttctagac tctaatttat atttgtctat gtctaacaaa
    21121 gtatattttc catattgatt aaccagattg gaattattaa acaagatcaa gggatagtta
    21181 tactcccttg gtaattctgc tgtaatgatt gaattttgat ttttaaattc gaagttaaat
    21241 tcacaaatcc cttccctaaa aaaatgaagc tctacatcat caaatacata gttacagtcc
    21301 aattccttat gaaaacctag ataaaatcct cttattaacg aatagggatt tgaaacatat
    21361 gatacaaccg gaaaattaaa ataatcttct ccaatacaaa gaggtatctt aaagattatt
    21421 tctgtatata agatttcatt attttcatta atttctgaat acatatcaga aaaggtaaga
    21481 tagaatgatt ctactgattg tagttgtcga tacaattctt gatctagaga cttaacatct
    21541 gggtataata cactagcatc aactgcttta tttagtttaa cttctagagt tatattatta
    21601 cctttaaatt tatttggtaa tcttatcata gttaccctcc cactttaatt tttaatattt
    21661 tagaaactat tttgtcaaac tcttcaatag aaagtgaagt atcaataaat ggaatatctg
    21721 taaaatatct aacctcatct aatttatgat taatttttat atgtaaattc tctccgatta
    21781 agtatctata tacttcattt gttattccat acctatcact caagatatct ctagggtact
    21841 tttgaattaa ctttggatat tttttagtaa tattgtcaat ttccttcatt aaaaagtaga
    21901 tataatcatt tctcaataaa tgatttactt tcgttatatc aagtttggta attactgagt
    21961 ataaagcgaa tttttttagt atttttttca ctgtgtgccc tttataattt cctgaaattt
    22021 caatattttt agaggataat tgaataagac aatccaacaa ggaaactact cgaatatttt
    22081 cttggctatc aataaattct agaaacaagc tttctatatt gaaattagag gtatttccaa
    22141 aaaatttaaa tttttctgga atctctccat gaagaaagta atccaaaagt ttcaggtaga
    22201 atttattaat atttatctca aaatatttct tagactgaat cttaaattcc gtacagtcaa
    22261 ttataggaat aaactgtcct ccatttttca caaaaatttt aaaataattt ccaacttttg
    22321 agttttcaat aaaaaatgga atctcttttg taataatata atagtctcta tcaattaaat
    22381 tcctaattag gtgttcgttt gaagtaataa caacaaaatc taatgtttta gacgaaataa
    22441 cttctatttc tcttagaaga ctagttaaaa aattcattgc taatgaatct tgtttattaa
    22501 ctaataagaa attataagtt tgattatata tttcccaata cggatttata tattctaaat
    22561 ccaagattct tgtccaaatt gtttcctggg gatagaaata tatcccttcc ttaaggcttt
    22621 catagtcatg agccattaac gctgaaccta tgaaccaatc acctctcaaa aaaccactat
    22681 ctttcagtgt aacaatatca tatttcttaa taatttcaga aaacattttc tatcctttca
    22741 ctctatataa gcaccaaatc atttctggag agaaagtttc acaaataata atatcatcat
    22801 tattaattat cgtttcttgg cttactattg aaaaacgata accttcttcc agaaattttt
    22861 tatttgccat aactttacta tgggtaaaat ctatcctcag atccatactt tttttcttta
    22921 aatagtttaa catcaaaatc tcagttgcag gttggataat cgccctatta attttataat
    22981 tacaattctc gattagaacc attcccttag taaaagagtg aaaagaatcc acaatttcaa
    23041 tccgcttatg atattcaaag ttgaaatctt tccaactata atttttaata ctactctcga
    23101 aagctacagg taataatata tattgccctt ttaatttatc aaagcaatta actatactat
    23161 caaaactatc atacagtaca atcacatcta cttttaattt tatacgattt attgcataaa
    23221 aacaatctgt tgcagttggt cctaatgtat ttattatcat ctttccccca agctcaaaat
    23281 acaatgttca aagtctaatc cttgattttc caaagatact aaatccctca tctctaaata
    23341 aatattctca gaagttttta cattttggaa aaaatattca cttgaatcca aaatttgtat
    23401 tttgtgttct tttaaaacag caaatattct ttcaaaatct aggtgtttta tctttttatc
    23461 gatatgattt aatgttgcaa tctccttcca atacttttct agttttaatt ccaaataatt
    23521 attctttgaa attaaatatt ttgatgaata ataacaaaat tcctgaatca tagagcgagt
    23581 ctgctccaca atattggtag gtgagtctaa agcttctatt atttgatttt ttatatgcag
    23641 attatctact aaaagattat ctacacttct aatactatta ataattccac gataacgact
    23701 tcgatttatt ctttccttca aacaaaaaat caaagaaatt ttatgtacaa agtgaaacct
    23761 tccctctaaa gtctttttta tactaattaa ttgctgaata ctgtctacta taactagaat
    23821 atcaatatcc gattctaatt tcccatcctt gattcttgga ttacctcttg ccaaggaacc
    23881 agtaataacg agtgaaattt ttcctacctc gcatttttta aaaaatgaaa ttagtatatc
    23941 taattcttta gacagcaagt cattcctata agttatcata ctttcctatt accgtataat
    24001 cttttccact atcagttact aagcaatccc tatattgctg taataaataa tttatttctt
    24061 tcacttcatc atgaaagact gaaaaattag catattctaa atcttttacc atatattcta
    24121 ctctaaagtg tatgtcatca aaatcttgat cattgatctg ttctaatttg gagttgcata
    24181 ctaaactcat ccaaccatca ttacatacga ttgtattcgc tacctctaga gactttggtg
    24241 aaaaatcata ctgtaaaggg ttgaatagct taatagagta aagcaaatac gctccccacg
    24301 agttataaat taacttgaat tttgttggtt ccgtactctt ttcaaaaaag tatatttttt
    24361 ttgaaattaa ttttaataat tccattaact cctttttatt atagtttaca ccttcatcaa
    24421 tatgtaaaaa aattgatagt tgaccactat tacttcctaa cttacctcct gtgaaaggag
    24481 cctctatata gtatccccct ttaatttcaa cagttttttt aaatttttca acgcaatcaa
    24541 tcctggaggt tgtaaaatca attactatgg ttttacgaag tgattgtata tttaataaaa
    24601 actcattaat gaaattatcc gtttcaatat gattactaaa acaagtgatt ataaaatcaa
    24661 cctgatttat agcatcaggt aattcatctt ctctaataaa tattattcca tttattgttg
    24721 aatttagatg cctactatat aggtatatat tatatttttt cgactgtttc aggattttta
    24781 atataccccg agtcattata ccatacccta taattaatac ttttttatgt ttcaaagtct
    24841 caccactctc taaaatttta cgatttaact taaatatgtt ttagctagta agtatagtct
    24901 ttagatactc taaagactta ggtgtacacc taagtgattt aaccaccaac aataatgata
    24961 atgtccatca ctagcatcaa aattgggaaa aattttgaaa ttttcttcat atttagactt
    25021 cctttcaatt tttatttatt gtacaataaa taaaactaag ttaacttttt gttgggaaaa
    25081 tgggaaaaac tatgaaatca aaacttggca tcacacttag aaaagttcgt aaaggcaaac
    25141 aaatcagtct atgctctgtt gctgatgagc atctttcaaa atcgcaaata tcccgatttg
    25201 aacgtggaga gtcagagata tcatgtatcc gactgatcaa tattttagac aaattacaca
    25261 ttactttgga tgagtttctt attttacacg atgaagacta tacaaaaact gagtcatttg
    25321 ccaacttaat acagtatatc cgtaaacaat attcattaca aaacatcaat aatatacaat
    25381 ctctactttc ggattcctca aattacactt tagattcttt tgaaaaaaca atggtaaaat
    25441 ccattttaca cacaatggat tcaagaatca ttccatcaga tgatgaatta cttcaactag
    25501 cagattatct ctttaaagtt gaaaaatggg gttattatga gattatttta ttaggtaact
    25561 gtgtacgaac aattaactac aactcctact tcttacttaa ctaaagaaat gttaaataat
    25621 tatatttact catctctaaa taaaacaaat aagcggattg tcactcagct agctataaat
    25681 tgtttcattc tcagcataga taaagaagaa ttttctaatt gctcttattt aattaatgag
    25741 ataaagggat tgttagagaa tgaattaaac ttttatgaac agacagtttt tctctatgca
    25801 accggttact atgaatttaa acgtcaatta agtagtggta ttgaaacaat gaaacaagct
    25861 atacaagttc tcgatatttt aggagaatac aagttaaaat tacactatac tgaccatttt
    25921 aataaactag taaataaaaa ataaatgaaa ttattctcta tcttttaact aattagtcgt
    25981 aaataatatt attctagtaa ggcattctcg tgaaatttta gaactgtaaa tttattggta
    26041 ttaataattt tcacaaacaa atccaatctt ctagctatct cctcatattt attaatttca
    26101 ttaccaagtt cctgttgtaa ttttaaaata tccgtattga gtcgatctaa cattattgat
    26161 tccgtcatgt tcatttggtc aaaatcatac ttagctaatt ttctagtctc atgatcttca
    26221 ctcttcaaat tgataaggac ttccgccatc ttgtttaagg tggcgatttt ttcttgggtt
    26281 tcttctagct gcatatcaat ctctgcaatt tctaatacaa gctcatcttt gatttcttgg
    26341 tattgtttgt tcgtgttaga tagttcaatc ataagattaa ttttagaaat cttctcttga
    26401 agacttttta aagttggtcg tctatagggg agtttttggc tatcgttgct caattgtctg
    26461 attaaggtcc tacccttgat gaaacaatta ttatccatgt tttctttatt atagacaaag
    26521 taagaagacg tttctcgaat gtagacttta tattttttct gattgtcttc ttccatagta
    26581 tccaattgat aattgggaat gaaaataaga ccactctgct taataccaaa agacactttg
    26641 atataaattc cctcatcaac tagcttctct atttggttct ctgcaagttc cacttcaaat
    26701 tcacgaacag catctctctt ttccttaaat atctcaaagg cttcctcaat ctcttcagtg
    26761 gatactttat ccttatctcg ttcttcttgg aaagcatggt actgttccta taaattctct
    26821 aatccttctg aagcaacgac ttccttattt ttaaaataat cttgaaaaaa tttgacatca
    26881 tataatttct tatcacttat tttttatgac ccaaacttat cttttgatta tcttcttcca
    26941 ggataaaagt tacatttttt tgttttaagt caatggttag attcaattct tttgcttttg
    27001 ttattaactc ttctaaagaa ttgacacggt tcaacaaaaa ttctaaatga ctttcaatct
    27061 cttgtttggc aaaatatgtt ttaaaaaagt cttcatcata taaatctcgt ttactaagtt
    27121 ggcgacctcg aattggtttt atcatcgttc tatctgtcat caaaaaacgg ctatgctttt
    27181 gactaaaatc aatctgaaca tgcaactgct ttgctttctc taaaaaatca tcaaacgatt
    27241 tagattgctg aagcaaaaaa taaagacgtt gtttcaattc aaatttatga ctagattcct
    27301 tatatttttt ataatctcga taggaataac gtttctcaat aatttttgca ccagccattt
    27361 tagaaatacg gtctgaaatc atacggaggt ttcgttccaa ggcatagttc catatcaact
    27421 ttttatctga attgcggtca atagcgttaa ttaggatgtg attatgaaca tgatctttgt
    27481 ctgtgtgagt tgctacgata aacttaaaac gacctcctgt caattccatc atggtctcat
    27541 aaccaatgcg gttaatttct tcaggtgtca gattatcttc aggagaaaat gattggatga
    27601 gatgatgggc atgaatagtt tgttggtgtt tttcttgtcg gtcatttctg gactcgtaca
    27661 acttgtcgtt attagtaaag ttaacattgt acatttctac catttctgca tggctaggaa
    27721 aatctaagta attactcatg ccaaaatcag atactaattt tagattatct gttttatctg
    27781 gattgaggat atatttaatc aaacgcctac gatatttttt tccgtgcgtc gcaaagtatt
    27841 tagtaactac catgaaactc cttcagtctt ttcacctcca cttgaaattc tttgtccact
    27901 tccttaatta actctccgac tcctttactc aattcttgta attggtcctg agaaatcaga
    27961 tggctttgat taatcgcacg cgcaatttga ttgatgttat ttccaatcct cctcaattca
    28021 aacactaact gttcataagt atcagtgtta atcgtgacaa atgacatatt gggattaagc
    28081 aaaacttttc tggcgtagac tgagaaattt tgacagtgac tcttagtaat acgatcattt
    28141 aattaattca attctgaatc agttagaaat atttttttag attagtacga taacgataaa
    28201 ccatagcagt ctcctatccc atatattttt cacagaattc acgactgagt ggctgagctt
    28261 gattgacttc tacaattaat tcttgaacac aagtcaataa gattgagacg tgctcttgag
    28321 tcacttgatg attctctctt gcgataatca aaaccaaatg cacatctcga ctgatctgtt
    28381 caaacttttg agactgccaa agggaaaacc attctttggc agctaactgt ttgtcatcag
    28441 tcatcaaaat tttatccctg acgaatggtg aaaagtgacg ataattatca acctccatca
    28501 ttttttcaat ctgttttagc tcatctgcgg ttagatttac ctcttttcga atgtcacggt
    28561 actgttcaga catctctttt cctcactttc atcctttctc gggtaaaccc cgaccccgtg
    28621 tgtcatacgg gaaatttctt aaagtccttg ttcggtcttt gcgagctcag gcattgtggt
    28681 cacaataccc aaaaaatcat atcgccagct aaccaaaacc ttccagtttt gacagctaac
    28741 cataagataa cttggtggct acgcccccaa actcccaggt aaaattctta gttggatttt
    28801 taaaagttga gaaaagtata gcagaagaaa gttggggaag ttatcacaaa tcaagtaggg
    28861 actaatctct aacaccactg catgtaccgt cctatattta tgatcagctc ccatcgttta
    28921 catttttagg tcactgtctt ttcataccag gaattagaat tgacaaattt aattagagag
    28981 gtattcattt aattgttcac ttcttcgctc catttccatt acagaaattt cttcaatact
    29041 atgtgttcag ctgactccca tgattcgttg tactacgtcc taaacgctca cggaataagc
    29101 cgtacatctt tcctagttta ctctcgtaat ttacgtatat aggttacgac acctatttgg
    29161 attttagagt tcctcatccg ctatatatgg cttcaagtca cgattctgtt tgtagaacct
    29221 tgatttcgct aattccttcc tatcccccct acatcacgat attcaggctt aggagtcgct
    29281 attggtttca tctgcagcaa atatccacag aggacttgga cctcagatgt acactatgcc
    29341 tgtcgaacaa agaaaaaagt aggctaaatt tctaacctac tttttctgac tctactctga
    29401 taaagccgtc tcatatatag acattttatg cttgaaggaa tcttttcctc cctctaattg
    29461 attgatgata tgatttttta tatatttttc actaacatat ccctgtgatt caatccatcc
    29521 gttaactcca tctgactcca taataacaac ttgatctgtc atagaatttg ttacaattgt
    29581 agcattatgt gttgctaaaa taatttgacg ttgagctttc acatctctaa actgctgaac
    29641 taaatgcctg taaatataac gattgtctag attgtcttca ggctgatcaa taatcaatgg
    29701 tctgaagtct ttagaatagt cactatatgc taataaaaaa tcaagcatgg ctacaacttt
    29761 ttgtcccaaa cttaatacac caacttcttt atagagaata tcaagttgtt gcgaagattc
    29821 tttcgagtta atattaaact ccaaaaatcg tgtattttct ttagaaaaaa tttttcgttt
    29881 atatgcacct gataagtgag aacctttttt caaaatgtca taactattga aatgagcaat
    29941 atagttaact attttttgat tattgaaatc cttcattata gtcagtgaat gttgataact
    30001 tccatctttc ttacttataa tattttcact taaccattga ttaacccatg attcttgttc
    30061 ataatcatat atacatacaa tatgcaattt atctgctgca ctaatttcta ctccatgtaa
    30121 aatatgagga tgtatatcat aaatcggata atttttcatt atgattgaga ctgccatttg
    30181 taacttttta atacctttgg tagtattatg atcagttact acaactattt ctattccatt
    30241 ttttatgatt gcctctgcta acataagaaa actaatatat tcttttgaac tagaaaaaac
    30301 aaccttatca aaattactaa aaaaaattgt cttatcaact tttattttct tattttcaaa
    30361 aaatatatca tatagttcat cttcagtaat ttttctatat ttcgttgcag tccaattaga
    30421 aaatagcttg taatcataag aaacaggtgt atgcaaatga attaaagtct tgtgaaagct
    30481 accgaatttc tctttggaat ttgttagttc ttgataaaca gactttatct tgttattaaa
    30541 ccctctcatt tctactctcc taaaaatatc aattgtttat ttttcaagta attcattaag
    30601 tctcttttcc cctaccctca acatctcctt ttctacctga ctccactctc caaacaataa
    30661 ctcatgaaga acatctgctg ctgaagttgt attttctttt gaatcatata cacaacttct
    30721 atctcgttgg taaatttgaa ttctttcaaa aatagctagt tcttccaatt gtcgtgtatt
    30781 atcaactaga tgatttacaa tgaaatcatg atgttctttt ggtgttgcgc gtgcttgatt
    30841 tggattgata gcgtacagtt cttcgtatcg aataagagtg ctcagatagg acagcttagg
    30901 ctttgtcgca atcaaggcta attgtacttc atatccctta tttttcaaga gttgtgccgt
    30961 tttctttgga acatcaactg ttcgtaaagt tccctctatc aaaagattgt atctcaaact
    31021 actcaatttt gttactaaag actctaccat ttttcctgca aaatctttgg tatattctac
    31081 actgtctttg ccatattctt gctgcagttc taaatagtgt ggatgctgag aacgaaaact
    31141 atcaccatct atgataacaa tatttccttg aaattctttc tgtttaatac gatgaattgt
    31201 agtcttaccg gcaccacttt gacctccaag caaaatcgct ataggttgtt tactggactt
    31261 ttttcctctt gtcagtgaac gaagattcct tgctaaagca tgtttgaatt cactatcagt
    31321 ataatcttgg atttccatta agctaccatc cgcttttcag atatctctaa catacgttca
    31381 attccatcca aatagccact atatctctct atttcatcaa aagtttctac taaatagata
    31441 ttcgtatgaa tcaagtcaga tagatcatca ctcattaaaa tccaaggatt agattcatca
    31501 tcaatgctaa ttccctgact atcttgataa cgatagagtc gagataatag attagcacct
    31561 ctttctttca caatttcaat tttcaaagtc aattcataat cttcaacagg attgagcatt
    31621 ttatcttctc ctacaatatc gacataagat acattaaact tctgacaaat gatgtcaatt
    31681 aattccgtag agactgaact cgttccattt tcataacgac tcaagctatt tcgagaaatt
    31741 cctataattc gtgcaaattc gggttgtgtt aagtcatgtg ttttacgtaa ggattttatg
    31801 ttctttccaa tcatagcaaa ctcctttatt tttataaatc cattatagca taaaaaagca
    31861 taatacacca attttggtgc gttatttctt gtttttctat cctaaacttt acttctataa
    31921 aagtcaccta aagagccata aatatttatt cttgtattaa ttttttcgat gcgcaaacga
    31981 tatctacaaa tacatctata acgattcacc ttttaggatt tttattgtca aaattgcctt
    32041 tatctacaaa gacaaaatgc ttataaaata gcttgaaatc aaggattatc acctttttcg
    32101 ttgtagcaac actccacatg tgattattag gctattagca aagcgtatcc aatacctcaa
    32161 taaagtgttg tttttactga tattttaact atattgtata gtctactatt taaatctcaa
    32221 ttaggatatt ttatagaata cccaaaattc aacaataact aaaagtaaga ttccattgta
    32281 tttccttgtt ggtctttcat atcacgaatt ttatttttca gaatattaaa gttacaaatt
    32341 tcatctctaa tatcgttatc cgctctgtag ccattaatca tctcagtcag agttttccct
    32401 ttactaccat tctttatagt agtatttact ctttttatac tgctttcaaa aggctcatat
    32461 gttttatact taattacttc gtctttaaaa ttaaataaag gtgtatccgg cttagcattc
    32521 cataaaataa tcaaccacat tatagcatta taaagctgct ttgcagtttc attccacttt
    32581 tcaggttgta aatttccact ccctgtattg tcatattctt gtctattatt tacatgagaa
    32641 tcacctacaa gtggattaaa aagaggtagc cctttgtgat taattagttc taaaaaatcc
    32701 cttgccgcac ccatgcaaca ctgaataact tccttcttgc catcaatttt actctcagcg
    32761 ataaatacat aatattcatc ttcaatagtt gctcctgcat cactatgttt ttgttgattt
    32821 gctaacagct taatatgtgc tttaggctaa acttcaaaat ctctaacaat tctttgtctt
    32881 gtttcatgtc ctctacaatt catttaagtt ctcctttaca agtttagtaa ctagccttat
    32941 tatactatat aagatatgaa atgtaccata atcttcatca actagttttt agaaaatcac
    33001 aaatccatct ggagagatga caagctgatt ctccaattct tggcaattgc ttgctagtgc
    33061 tactgcttct ttctctaaaa gataatcttc tgttgattgg ttgaatattg ctttgaggat
    33121 ccgtccttcg tatttccatt ccagagctac taaatcagat ttgatttctt gaaggctata
    33181 cttgccatgc gaaataatta ctgacgcgta tttccgaatc ttaatcagcc tcttcataaa
    33241 gttcagcata tcattgtcac ttgatacacg ttcccaaggc atacaacgac gacaatctgg
    33301 atctggtcct ccagtcaagg ctagctcggt tccgtaataa atgcacggtg ttcctttttg
    33361 taaaaagaga aaggctaagg ctgatttaac cagttgaaca tcttcattgg ccgtccacag
    33421 gattcgctct gtatcatgtg aatccaagag attaaacatg acctctgaaa tctgctgctt
    33481 gtaatacata gactctccat tgatttcatc gatgaactgg tctgtcttct taattcctcg
    33541 taagaaatag tccttgatac tatcagataa aggataattc atgatggcat ggaactcatc
    33601 tccatttagc caaggctgag atgtatgcca gacttctcct aggatataaa gatcaggatt
    33661 tttagctaaa actgccttac gaaaatcctt ccagaactga tggtcaatct cattagccac
    33721 atccaaacgc caagcatcga tattaaactc ttcaatccaa taagtcgcaa cctttaaaag
    33781 ataattcttg acctctggat tggctgtatt tagcttaggc atatagtcct cgaaaccaaa
    33841 aacatgatag ggtaagtctc tcttattaac tagtttttca gttgtcactg ggaattgttg
    33901 aatatggaac caatccttat aagcagactg ttcaccattt ttgacgacat ttttccattg
    33961 aagagattgc gaaccaatat gattaaatac cgcatccagc atgactttca tgccacgatg
    34021 atgcgcttga tccaccagtt cccgaaaggt ctccttgtct ccaaaatgac ggtcaatttc
    34081 aaagtaatct gtcgtattgt acttgtgatt gcttgtagat tcaaagatgg gacaaagata
    34141 tagtccagta atacccaagt cttgcaagta atccatatga tcaataatcc cctgtaaatc
    34201 accaccaaag aaatcatcgc tcttaggtgt gacagatgaa tcccagtcta aagtcccttc
    34261 tgggtttaat agagcattgc cattggcaaa tctttcagga aatatctgat accataccgt
    34321 atttgaaacc cagtcaggaa ccttgcaggc atcaatcttg aagataaggc aacttaaatc
    34381 cattcccaat tgcatgaaga ttttctagag aattttccac acacccttta tcgccataca
    34441 aaatattttg accttctgta tctctgagct caaagagata ctggatacgt gcaaagtcaa
    34501 ctgacacttc aacctgccaa tggtcaaata aggtaccaga agttatcttg accatttctt
    34561 ttgtatcctg ataaaactcc tccataaaga taaaagggtc cccatagtgc aagttgatgc
    34621 tttcaatgtc ccctttctta gttcgaattc gaatatggag tttcttatcc ttataaagat
    34681 aggcatactc cgactcaggc ctatggtaaa tagcactcaa ttccatcaat ttgtctccta
    34741 aagtattcat tcaaatttta cgcaaacgtt ttcaaactca atgaatccag tatactattt
    34801 ttgtaaacta tttgcaagga atgtccgttg ttaaaggaac tatcttttaa agtatacaaa
    34861 aagccttaaa aaaggctttc tctatatact aatcctcttt cggttttgaa aatacttcta
    34921 ctcgctgagc taggactttg atttctacag gtaggttatc tgatttatct ccgtcaacat
    34981 ctgactccaa ttcactatct gaagagattt taatattacg cgctttgata tactcgatat
    35041 tatcatttgc gacaacatcc ccttttaata aatcaggaat gacggataat ttggagaata
    35101 tagaggcatc tttcagaatc aaaatgttgg catagccgtc cttgttttct tcaaagattt
    35161 tcttatcagc gaagtaattt gtcaaaagga ccaaaacatg gctagcttca ccaacataat
    35221 ttccattttc tgtctcaacc ttaatgttaa agacctgatc tgtcatgaca gacttcatgg
    35281 tatttacagc ataggttaaa ataccgaatt ttgttttgtc ctctatttca acattgtgaa
    35341 tcgcctcagg cagagaaccg atactaaaga tataaccaaa atagttgtca tttgctttac
    35401 cgatatcaat cttattgatt aaatcaaaat ccagttcgtc aattgcgcca tcgatgtctt
    35461 gattgatttc caaaagtttt gtaatgaggt tacccgtacc gcctgggata atccctaact
    35521 taggaatgta gtctctctca tcaatacctg aaatgacttc attgacagtt ccatctccac
    35581 caaacacaac cactgcatca tactgctcac gagaagcttc ttcagcaaaa tgtgttgcat
    35641 ccagcgcttt ttcggtaatt ttggtttcaa catattcaaa gtattctttt gctttattct
    35701 ccagcttttc tttgtaatcc aaagccttct cgccaccaga agtagggttg ataattacca
    35761 ttgctttttt cattgatttt atccttaatt ttaaacagaa atgtttacat ttcgtcgtat
    35821 gcaagtaaat gtaatcctat tatacaatga aaatacagaa aagagaaatc tgacatactg
    35881 gagattaata cgcttttatt ctattttccc atcgcctaac tacatccttt aagggttcat
    35941 ccaagtaaga ataggcctta tccttgatcc aatcaggaat accgtaagct gcctctgcta
    36001 tgctacaagt gattgctgcg agagtatcac tgtcgccacc aagtgagatg gcatttctta
    36061 tcgcatcttc gaagtctcta ctttcaagaa aggcgataat ggcttgaggg acagtttcct
    36121 gacatgtttc gttaaaacga tagttaggac ggatttcatc taaagtttga gatagattgt
    36181 aatcgtattc tttttctata taatccttaa ttcgtctttt acactctgta ggattgtcgt
    36241 taattgattg ctcgtactct ctacaataac caccaaagta aaaacgacat agaaagatag
    36301 catcagctgt agccatagcg cctttgacac cttctggatg attatgagtt acctctgcag
    36361 aaagactcgt aagtcctcta gatgatggcc acataccagt tttcgcataa aaaccacagt
    36421 ccatgatcca agcacatgga gaaatacgca tagctgatcc attcccaaag ctattataag
    36481 gctcacggtt atcgctgttt agccatgcat taaaccgagc accgtaatca gcattcggat
    36541 acattctgcc atatttcttc atcgcgtcaa tgaaatcgtc tttttgtcca ccattcataa
    36601 ttgcttctgc aacagcacag gtcataaccg tgtcatctgt aaaaaagcag tccttccgaa
    36661 ataaaggaaa gtcctttgtt ttgatattgt tccattcgta aacagaaccg acaatatctc
    36721 caataattgc tccaagcatc agattcctcc ttgttcattt tgatgctttt tatattggtt
    36781 atctaccata tttattttag aaaataacat cctgttggat tttaaaaatt tcattttttt
    36841 caaaataggg ttttaccatt tctttccacc tagctctatg aaaattgatt gattttaaag
    36901 gagataggcc ataatttccc aatgcataac catcatttac ttcaacaaca agtgttctgc
    36961 catcgcgagt aacaccgata tctagtccat aagctattgg cgcatctttc caacatgata
    37021 tcgcttcatc aattacactt gcatcaaatt gtgcatgata atcacctgta tagggtcgaa
    37081 catctaatac gcgaccatct aacacaaaac aacgccattc agctatgaat tctacaacct
    37141 cactaatcca tataggatag tcgaaaggta gaccaatacc tattaaatca tgggttccat
    37201 taacaactct tccagtaaag acttttgaac cagctttagg cttaataaat tttccccaat
    37261 tatcaggtat attcacaatc tctcctaaaa taccagcata aatctttcga ccataaaact
    37321 ctttaagctc aataggatag tcatgaaccg gaacgtttaa gcccatcatt tttagtaatg
    37381 ctctagtctc cattatataa tctacaacta tatcttcact tgttaactct tttatttcag
    37441 aaaaagattg atataaaata acttcttctc cttgtaagta ggcacctact tgagcattgt
    37501 atttattaat tgaaacctca cttggtaatt tactttgtct aatataaaca accatttcat
    37561 cactcctata tcactagtgt tacaccaatt tgtaaaaaat aatagcaatt ttgctcttat
    37621 ttttttgagt aaatagcccc cataatatca tcgaaataat caacggtatt taggagtaat
    37681 tcaataacct gggactttgt tagtcgcatt ccccttctat ctctagcatc ttctactaaa
    37741 ttttcaagtt tctctagatt tttatcatcc aagctaatca ttattctatt tttatcggtt
    37801 gccattttca tcacctcgag ttaattctat cacaggtgta acacttgtgt caactggctt
    37861 ttataataca ttagtttaaa agtggagagg atttttaaca cagtaacttt aaatctttgg
    37921 tattaaaaaa ttttcacaat atttatagaa ataaaatctg tctcaaatca gttatcaaat
    37981 ctagtataaa ttatgagcgg ctactctaat actttccctc taaacaagaa aaagacttac
    38041 actcaagggt tttcttcccc ccccttcgtt ataacgtttt gactctttta ctagcaaagg
    38101 tatatactca caaggaactt tggttgacta ttgaatctct ccaacttctt ctttaacata
    38161 tccttctaca tcttcaatct ctacaaacat tgggtctaag tgacacaaga aatgccaaac
    38221 ttcgatccct ttttttctgt aaagaatcgc ttcaccgtct tcacttccga aaaagcttct
    38281 gtcgatttca tatccgcggc tttctaagaa gtcttttgct ttacgatagt tcgtttctct
    38341 tgtttcgaca taggctttaa cttcatggtt gttaacgaca tatgcatcaa tttttgaata
    38401 tccttcgatc actctatcat ttttgaggga taaatttgaa atctctttcc aaataatgtt
    38461 tacattttcc tcaggatcga acataaattt agataaagga acaatatttc cgttaaaaat
    38521 aatttccata taatccggta tgtttttagg attaaaatac tccacttcaa aaccatcttc
    38581 tgtttccaga gtgtatcccg ggatttgagc tacaaaggct ttcccatctt ctatggaatc
    38641 aaatgctact aaatctttag aataatcatt ttggtacaat tccaatataa ccatcgataa
    38701 tctctccatt ttcattatca ggctaatgta aataagcacg tcacctgacc aattcaggct
    38761 ctctgtatca tctcatcata tttcctactt actttacgag tcctataccc agaacacacc
    38821 ttatcgacct tcggtctcac ctcgtcgcat tggctgaaca tctactttta cttcgctgat
    38881 gcttcaactc gtacaagcag tgataccgcc tcagcgtgat gcgtcagtgg gactcaaaaa
    38941 gtttggggaa ccttttgagg attaactacg tttctctaat aaacttacac attcaacttg
    39001 ttcatcattg tccaaatcta tgttgagatt ttcttctata attggtagct taaaagtaat
    39061 ggattttagc cattgtccgt tagattgttt ttcttcataa acttgaattt cagaaatcaa
    39121 agctgaaatt aactgcctac gctctacatc attcatgact ttatagagct tatcaaaata
    39181 gatcagaacc ttatatatgt tatctcctgt aagcttttca gcttcaatag tctgtttctt
    39241 tgctttcgca tcaattagtg atgattctaa ttcatctatt ttgtcataca tacgatatag
    39301 tctatcatct aaatcctgtt tccttctctt ataatgctta tcttcaacat ctaaattatc
    39361 tatttcctca attagcttaa actttgtaga atgactcttt ctcaattcct tttggtaatt
    39421 atctatttct ttttctattt cagaggtatc caccttcatg ttgatttttt cttgcatcat
    39481 agaagcaaat ttcggattac ttactatctt gacaatcacc tctgcaacag catcatctaa
    39541 caattcttct ctaatttgct tactgaatgt acacttatga cctcttatca tctgcctatg
    39601 gttacaacca tagtaataaa aatctttata ctttgtgcca tctttctttt tcttgataca
    39661 cttgttccca aacattccca ctccacatat cgggcatttt acaattccag aaagcaagtg
    39721 tgtgcgtgta tcttttcctt tattcacatg ctcatatttc tttgcttgag attttagctt
    39781 aacctgagca gcttaccaaa cttcatcgga aactatagct tcatgtatcc cttcagatat
    39841 tagatattca tcttgttcaa cctgcttata ttcatttctt gtaccatgaa ctttttctaa
    39901 agttcttctt ccaaatgcta ttttcccatt atatacagga ttctttaata tctttcttat
    39961 aagacctgca tcaaacaaag gattcttacc attctgtctt gggatttttc taattccatg
    40021 attctctaag tatttagata tcccattggc tcctatcgta gtatttacat actggtcgaa
    40081 aatcgttctt attgcaactg cctcttcctc atttataaac agcttgccgt cttcaagttt
    40141 atatccatac ggagcaaagc caccattcca ttttccttcc cttgcttttt gaatgcaacc
    40201 ttccattgtt tgaatacgga tgttttctct ttctatttca gccacagctg ataaaacaga
    40261 aatcattagt ttcccagcat ctttagatga atcaatgcca tcttcaacgc agataagatt
    40321 aactccataa tcctgcatta tctgaagtgt agaaagaaca tcagcggcat ttcttgcaaa
    40381 tcttgataac ttaaacacaa gaacaaaaga tactccatct tttccagatt ttatatcttc
    40441 catcattcga ttgaactgta ttctaccttc aatagacttg ccagacttcc cggcatcttc
    40501 atactctcca acaatttcat aatcgttgta aatagcaaaa gctttcattc gtgatttttg
    40561 tgcctctaac gaatacccct ctatctgtat tgacgtagat actcgtgtat agaggtatac
    40621 ttttattttt tcttttgaca tagtattaac ctcaatataa tttttctata tcatatataa
    40681 tttttttaat ttaagtttgg actatcattt caagtatatt ataacacttt tattagtccg
    40741 tctcaatttg tgtttttgcc atgtcaaaac tatttttcat ctcttgattt tttgctggcg
    40801 ttggatcggg tagattatct aaatctaaag caccagcata ttttgcaatc agatttgcta
    40861 ttaaatcagc caatccattc cagtcattgt ccaatatata cctcctctaa agttttatat
    40921 ctaataatta tttgtttaat taagtttttt gacattgaca agtgctttgg attagcaaca
    40981 taggaatctc acctccgcct ctattccgga tgagccggct tcaaccttag aagtatcatt
    41041 atcctcattt tcttcatagc ggatagggta tccctcccta tattcaaact cttacttatc
    41101 gctcactttc tttttactta gcagaacttt ttttgccgaa ttattcagcc gaaagatctt
    41161 gacggatagg ttattacgct ccaaaaataa ttaacgtctt gtcttggtct attcaattgt
    41221 taaggttcaa aatttatcga gagttattaa tctttttaaa atttgaccat cagaaaatat
    41281 ttatcttaat gtaacaaaat tctataaatt accctcttat acttaacagt gaaaagaagt
    41341 ctttcttggt aaccaatttt gaaatagaat ttgcttatat aaaaaggtca aattcccact
    41401 gcataagtag cagtgaaaat tagaccctct tggtaactgt catctaaaag tcttctagca
    41461 tttctttaat tttctaatcg cctttaaagt gtcatattta tattttttta tctctggcat
    41521 actttgatac ctttttagac ttaaagtctt taatagtgcc tttccacctc tttttatcta
    41581 taaagattct cctacatcat aattcatttt tttatttaaa cctttctgtc ttagtttgtc
    41641 tttatcttct tcataccatt ttaagattgt cacatagtgg ttttgatagg tcttaccact
    41701 gctttccatg tatctggata gtttatttat cattatatct gtgtgtgagt ttaatttttc
    41761 ttttagattt ttatattctt ctttgcttaa ccttacattt ttgaattctc cataaaaaat
    41821 gggggtggac tttttatcta tctctccctc tctctcttta tctatctcta tatctttcca
    41881 tgtaattcca atctggagta cctctactgt ctatcggtaa tttaattttg atatctggca
    41941 atactgtgct agatatttga tctttatatt cagtattttt taaagcttgc ctaataattg
    42001 aagttaaata gaatgctact tctttattca attctttatt ttttaatttt aaacaatgaa
    42061 ttttcatatc taggcttgct ttatatttat gataaaagac tgctcctaaa aatgaaacag
    42121 atataaaatt ttcaaaaact ctataatttt tatcatctat atcttcgtag taacctaaga
    42181 taccattgtc aatatttgta gcactaattc taggagtttt tccatcgagt aaatatcttt
    42241 ttggaataga tgagcctgtt ggtacttgac tcgatttccc ctttttttcg gtaataaata
    42301 tttcttttta ttttgttgtc cgatattttt cctacctgtc ctttgtagga tgagtatttt
    42361 ctagattttc ttgaataact ttttacttga agttttagct tttgaactag tcgttgtact
    42421 ttctttttgt ttattatcag tcctgatctt tttaatattg ctgttattct ctatatccta
    42481 tttttcattc atgatattct tttactaatt ttatcttaaa ttctgtgctg tatttgccat
    42541 taaaaaactg acctccttta gttagttttt tggcctaact tttgagggtc agttcaaaat
    42601 ttgcgacttt taaatgaatt ccgatattca attattaaga gctaacatgg tgcttgccaa
    42661 taggaatcat tagaggcgaa ttggaaatag ggtcacgtat aatttttgct tcaagattaa
    42721 agatatcttt aactagttta tcatttagta tatcttcagg ctttccctct gcaacaagtt
    42781 taccttcttt aattgcaaat aggtaatcag cgtatcttgc tgttagattt atatcgtgca
    42841 aaatcatgca aatggttgtc ttatattttt ggtttagatc agtcaagagg tctaatagtt
    42901 ctatttgata tgagatatcc aagtaagtag ttggctcatc taaaagtagg atacttgtat
    42961 cttgggctag ggctagagct atccatactc tttgcctttg acccccagaa agttcttcaa
    43021 ctaggttatt tgctagatct tcaacattgg ccttaaccat tgatctgttt attatttcaa
    43081 ggtcatcttt tccaagactc ttaaaaggct ttctgtaggg gaaacgacca cggcttacaa
    43141 gatcagctac tgttattgat tcagggatta ttggagattg aggtaatata gctatgtgtt
    43201 ttgctaaatc tttttcttta taagaattaa ttgatttatt atcgagcaat acttctccct
    43261 ctaatggctt tataagtcga gacaaggttt taatgagtgt tgatttccca caaccatttg
    43321 acccaataat aactgatatt ttttcttcag gtatttttat atttatattt tccaagatta
    43381 ttttttcatc ataaccgcag gtaagattat ttgaccacag acctttcatt atatattcct
    43441 cctgttcatt tttattagta agtatattaa gtatggtgaa cctaacaagc cagttacaac
    43501 acctactgga tatctagctg gtaaaatatt ttgagagaat atgtctgata acaaaactag
    43561 taaaattcca accaatccag ctaatattgg gcttcttttc ttgccaatat ttaaggctat
    43621 gggaccagct aaaaaagata tacaagctat tggtcctgta attgaagtag aaaaagcagt
    43681 taaagataca gcgcaaaaaa ttaaaacaag ccttgaaagc tcgggatttg ctccaagtcc
    43741 gattgctatt tcttcaccaa gttcaataat ttctagtctt ttattaaaaa ataaaactaa
    43801 tatagtagca ataatactta ctattagaac aagaggtatg tcatctaact ttgtaaaaga
    43861 taaagagcca ctgagccatc tcataacttc ttgtaattca tatcttgcta ctttcaacaa
    43921 taaaaatgag gtgcctgctc ttgtgacagc ttgaaaacca atgcctaata ttatcagtct
    43981 tgctgctgaa aaaccatctt ttttagctag taaaaataat attaaagatg atgttagtcc
    44041 acaagttatt gaaataattc cagtagttaa actatttgtt tttaatacca atatgcaaaa
    44101 gaccgctgca atagatgaag aacttgtgac accgattata tcaggacttg caagaggatt
    44161 tcttaacata gtttgaaaga taaatcctgc caatccaaaa gaccagccag ctataattcc
    44221 tgctaataat tttggtaatc taatttccat aatcgaaaaa ctagctccag gaacagtttc
    44281 actatttaag actttaatca aagttgaaaa agaataactt tcatctccga taagtaaaat
    44341 gaaaaatgat agactgatta ttattaataa aaatagtgag gaaaatagtg ttattctatt
    44401 ttttcttttt tgaataccta taattaaatt ttgcattagt tattaacccc tctatttttc
    44461 atagttacat aaataagtac tggacccccg attattgcag taattatccc tacttcaatt
    44521 tcacctggtt tacctaacat acggccgatt atatcacata taagcaagag ctctgcacct
    44581 ataaaagatg aagaaatggt cattgtgcgt atatctttgc ttataaataa gccacaaaag
    44641 tgaggaacta taagacctac gaagccaata ggtccaccaa ttgcagtaat acttgaacat
    44701 aaaagcacac ttgcaattat tgcaagtgat cttatcctat taacattaac tccaagacca
    44761 acagccattt catcacccat agctaaagcg tttaaatctg atgaaataaa tatagctatc
    44821 aaatgaccta aaattataaa aggtagtagt gtagatatag aagataatgt agctgctcca
    44881 aggctaccta tttgccaaaa tctaaatttg tctaagacgt tattattcgg taaaattaaa
    44941 aaacttacaa aactgcttaa agccatacta acacaagttc ctgataaggc aagttttata
    45001 ggggtaaggc ctgcttttcc gcttacagca atcgcgtata caaaaattgc acttactaag
    45061 ccaccaatga ttgcaaaact tatatggctt atgcttgatg aaattcctaa aaaagaaaga
    45121 ccaattacta cactaagact tgctcctgtg tttataccga gtatacctgg atcagctatt
    45181 gggtttctag taactgattg catcaataca ccgcttatgg caagactaga acctgctaaa
    45241 attgcaaaaa tagttctagg tattctttta tatataattg atttaataaa atcatcattt
    45301 gtattaccca ttccaaaagc tgctaaaaaa tctctgatat taatttcttt tgttccaagc
    45361 tttaatgaca aaaatattgt aataagaaga cctaggcaga ttacaaaaat tatgcctagg
    45421 tttatttgtt ttttatttcg catttttgca tgcatttcct aaaagattta ggtattcttc
    45481 aatagtatag tttattgaaa gtggtgttgg agtgcatgag gctgctaacg gtgtattatc
    45541 tggaattaca gcaacggcac catttttaat tgcatttatt ttacctaaaa gaggatcttt
    45601 ttgtaaagct tcaagagttt tatcatcacc ataagttatg attacatcag catcatttat
    45661 cttatttgct tcttctgcag aaatttcctt tgcaaaacta tcttcactct caaattcttt
    45721 taatgattca gggaaaacta gacctaaatc tgttaaataa tttgctcttg gatctttgct
    45781 agtataaatc cagaattttg atgtatctgc agcattaatc atagtaaata atactttttt
    45841 tcctttgatt tttcctttga tttctggatg tttttctaat tctttggata tacgagcttc
    45901 agtatttttg attaactcat caccttcttt ttccatacct aaggcttttg aatcaatttt
    45961 aatcatatct ctccataaag tttgccaagg tttagatttg tatgctgcta caggagcaat
    46021 ttttgataga gtgtcataat cttctttagt tataccagaa taacctgcta agataacatc
    46081 tggtttagaa tttgatattg cttcaaagtt aagtccatcc aaatcgtcaa ataggttagc
    46141 tttaccattt agttctttga ttttttcttc tgtccatggt aaaactcctt tatcagcact
    46201 tacaccgtaa tttgcttttg aaaatccaac aggaactatt cctaaagcta atgctacatc
    46261 atgatttccc caagcaatag ttgcaactct ttcaggtttt ttatctaata tagtttgacc
    46321 gaaagcatga tctaaaacta ttttatcagg cgcatgctct ttagaagtat tttcttcatt
    46381 tttaacagaa ttagaagaac aagcgctaaa aactatacac atagctaaaa tagctattag
    46441 aaaaaatttg tttttcataa aaactcctta aacatatttc aagtctattg tatcgataat
    46501 aattatcatt gtcaatagat acagttacaa atttaataat ataatttttt caaaaaagga
    46561 tctagttttt atttttagtt aaattatgtc tatatttttc attaactcat caataaaaat
    46621 ttgtttgcta atatctcttt cttctgattt tgtttcaagg attattgcta catcattcat
    46681 atttttaggt aaataccaac catctggctt atctgaatat cccttgaagc ctaattgatt
    46741 aaaagtagtt atttgaccag taccttgatt gatgttttct tcaacttcat taaagcctat
    46801 acttctcttg cataatccct aacttgatct tctgtcctta aagtcatttt ctattcctcg
    46861 tcactaaaat tatcttcaaa actaataata tcattaggag tgcaagataa agccttacat
    46921 attctttcta aattcttaaa tgtaattggt ttatcctttc ccatttgtgc cataacattt
    46981 gttgtaagtc ctgccatagc tattacatct gttttcttta gtcctttttt tgctaactgt
    47041 atccataatg gtttatagtt aagtgccata atatccctct ttttttcttc attagattta
    47101 tttaattata gcataaatat tgattttatt caatcttaca ttgatttagt gatttgtttt
    47161 agagaatttg ttgtgttatt ccgtccttat tttgccataa attgttttaa gtgggacctc
    47221 ttatccttac catttttacc tcctaatttt gagtataaaa aagacgatag agtttttaat
    47281 ttctatcgtc tgagatttac atattaaatt ttcatcacaa aataagactc tttaaagaat
    47341 ctttaaattc attggtatgc tgcttacaat atccattatt aaaatggata ttgtaagcag
    47401 cataccaact atttattttt tgagttttaa actttggtag aagtcttgaa ctccttatat
    47461 ttacataact atttgcctct ataactgtta tgacacgaaa ccaacaagca agttcaagca
    47521 cctccatatc tttattcaaa tgaggactaa gatattcaca aactttatca taaacctctt
    47581 tatctttttt cataaaaggg gcatacaact tagcaaattt atcctaaaat tttttgttgc
    47641 ctttatcaat catttcaacg ctcctttaaa tataaaaatg atcctatcaa tctttatatt
    47701 gagcctattt tctaattgat accttgcaag aaaggaataa tagctgttcc tataccaagt
    47761 aggaatgtaa taaatgcaga aagtcatata ctgtcattct tttctattaa atcattttga
    47821 agtgtctcaa agcatccatg atggcttctt ctttttcagg tgtacactgt ggaataattt
    47881 gtttatcctt tttagacttg ttgtaatgtt ctcgtaattc tattccacat ttctttttta
    47941 tctgtgcaat atataatgtc gaaactttta attcaaattt attccaaaca tattctttga
    48001 tttgagcata tgttgctttg ctctccgcac ttgtcaaatc catctcatcc agctcaattt
    48061 caacacttat gtgcttatcg acatcaagtt tggacaaaag tgctaccgtc tcgacgtgat
    48121 gcgtttgagg aaatagatcc accggctgga ctttcttcaa ttcatatccc aattcttggt
    48181 agagtttgat atcacgcgcc atggttgcga cattgcagga gatataggcg atgcgatcgg
    48241 ctcctgtttg ggcgcttgct ttgataaagc tttctgtcaa gcccttgcgt ggaggatcaa
    48301 ccaagataac ggttggttga atcccatctt taagccaatt cttcatagca ttttcagctg
    48361 tgtcacagac atagtgggcg tttgaaatat tgttcagctg agcatttttt ttactattct
    48421 caaccgcttc tggaatcagt tcaacaccgt agacttcttt gacatgcttg gcgactgata
    48481 aaccaatggt tccaatacca gaataagcat caataaccac gtcatctttt tttaactctg
    48541 caaagtcaat ggctgtttga tagagtttct ccgccatttc agtattgact tggtaaaagg
    48601 ctgggccagc gatttggaag tcatttccca acatctggtc cgtaatatag tcttgaccat
    48661 aaagagtgcg ccactcctta ccaaaaatcg cattggtatt ctggtcgttg atattttgca
    48721 tgacagacac aatctctggg aactgcttga taacttgttc aatcaattgg tcaacacgaa
    48781 aaacttttgg acgagttgtc accaaaacga ccatgatttg tcctgaatag tgaccacgac
    48841 gcaccacaag attccgaatc aatccagact gttccttttc gtcataaggt tttaaatcaa
    48901 aacgacggag caggtctcga agagctacta cgacttggtc aatgacagga tcctggataa
    48961 agaaatcttc aaggggcatg aggtcgtgcg aattcttacg gaaaaatcct gtttccaaga
    49021 caccattcac tcgacgaacg ggcacctgcg ccttattgcg atacttgact ggatgttcca
    49081 taccaagcgt ttcagcaact tctacatctg caattccagc aatcttgtag agactgtcct
    49141 tgacttgctt ggttttaaac ttgagctgtt ctggataaga aaggtgtcct aaatccgcga
    49201 ttcctgaacg caggtaagcc aaatctagat cttgattacg gtgtggtgac tggacaaggt
    49261 atttttcaac ttttccaaag ccaatctttt tattgacctt gaggacacgc atgagaattt
    49321 tttcactcgg taaagcattc tctacaaaaa agaccaaacc atctaccttg gcaactcctg
    49381 ccccttcatg ggtcaagtca acaatttcaa cttctacaat atcatttttc tttaacattc
    49441 ttttctcttt ctattggccg acaaaaaaga cggtaacgtt acggttacca tccattatac
    49501 catgaaattt cttaagaacc aaaactcttg aagaagttga caagggcttg ccagagggag
    49561 cttaagaagt taccaccgtc ctctagcgcc ttatccgcat caaagttaag gttgatattt
    49621 ttaaaactgt cgccagcttg tgatacgatg ctttgtttaa ggtcatttag ggttttagtg
    49681 aaatctgcat tgctgaggat atcactcttt gagagattca aggcaaaatt gatgatgata
    49741 ttgatctggt ttcctgttat gacctgatca agtttgtaat tttttaaggt atcttcaaca
    49801 atcttgcgga tatcttcttc tgtcagattt cccttgcttt ctttagcttt ggcgagtcct
    49861 gacttgatat cagctagggc aacgtttaat ttattagcat catagcctga tttgtccttg
    49921 ttttcagcat tgatatctga caaagctttt agctcttctt gagccaaatc tttattagct
    49981 tgtggcacct tggctccatt agcctctagc gaatagtaaa tccctgctaa agcactttct
    50041 cctgtaactg gaataggggc tgctacagtg attttggcat gttccatacc cagcgttact
    50101 gctgcgtttc ggtacatatc ctgagtcacc ttagtgatat tttctggtgt ttcaatcttg
    50161 acctcaagtg gcgatttgtc acctagcttt tgaatcttgg ctgatgaata caactgtaag
    50221 ctagagtcat tggccacatt catgatttta gaataaacat caggtgtcat ggtcttgagt
    50281 tctttggtat ctgttgaggc attgtagccc agttttttaa gagtttgatt tttttggtct
    50341 tcagataggg aggaacctag gacatattca ggttggacat aggtttcatc gataactttt
    50401 tgaacatctg ttgctgcatg gacgctattc atagctgtta ctgcccacaa gaccgcagca
    50461 ctagtcagaa agagtttctt tctcataggg aatttcctcc tttacttctt tatagtaata
    50521 tatctatctt aaagaaaact tataacaaaa acacctggtc tagccagatg ttgaaaagag
    50581 agtgaaacat ttgatgatgt aaaggttaag tcgtacctgt ctagaataat aataatttcc
    50641 tccatttaca tagagttcag caccgtgaaa aatggaaatg gggtgaatat aactataagt
    50701 ctttccagtc gtattaccaa gcaagggggc aacagtctca cgagagtact gtttggctag
    50761 agccaaggta ttttccttgc cattttgggc gataaaatcg atataggcag gtccaaaatt
    50821 ataggcttga acagctgtcc agatatctac acccttcttc tgcgccagat agagattgcc
    50881 tgtcagagtt tgaatgcctt gccgaatgct agaggcatta tcattgatgg tgttggtgga
    50941 accacttgca gactcactag actgcataac atcgccttct tttccttttg tttcagtata
    51001 aatcatagca agcacaagct cttcgtttgc tggggtgtct ttttcactca agatttctcg
    51061 caccatgggt tgataggtca tgacttgttt gacatcttga tgaacgcggt aagctttata
    51121 gccagcaaaa aggaagactg ctagtacaag cactcttcga attcgtttaa acattattta
    51181 ctttggatat cctcgatatt tttgattaag atagagtagg ttccattttc gttttggata
    51241 aactcaacag actcggcgtc ttgatagacg ttattgggaa cgatgagctc aattccattt
    51301 gataaggaga gtttttggtt ttcaaatttc tttaattggc gacttgcatc aatttcatca
    51361 aattgaacag gttctggtac ggcttctttg acttggtcaa taaagctcaa acgagccgtc
    51421 agattgttgt caaaaaggtc attagccaat ttctcaggtg acaattcatt gctttcttct
    51481 aggttgttga aaatcgctga tttgaccttg gattgaaatt gaaaatcatc tgtgttaaaa
    51541 gattcagcaa ttctctgggc tgttttttcc agttccttga tagatttttt aggagaaatc
    51601 ttaggagcga cagcaagaag attatctgaa aaatagttca aaaaagtccc gttgtacttg
    51661 attcgttttt caatcaggtg atacttgcga ctctgaagat tgaccaccaa ggcctcgtca
    51721 gcacccgttc caaatccagg caggttattc tgagtcagct tgattggatt atcaacttct
    51781 cctccgaggt gggtcaaggt ctcccgcagg gcaattcgca agaaagcgaa atgttctaca
    51841 ccttctttag aaaattgaac aaaaatcaag tcattggtct tgagattttc agaaatgcta
    51901 aactcctctt tccagagatt agccagcgtt actgatgtct ccaacaaatc gtctgtaata
    51961 tgattgaaga agggattttc ttcttcgaaa atcccagtct tggcttcatc tgaatacaca
    52021 tgttcaattt ttttacgtag gtattcttcg atttttggag taatattgag aaacttatct
    52081 gctaagaaca gctcggtatc atccggactg aactggtgaa taatggcttt cttaatataa
    52141 atgtccataa aagttttatt cctcgtataa tgggaaggca tctgtcaatt ctttgactgc
    52201 acttctcact tcttctaata cagcctcatt ttctgaattc ttaagggttt taatgatgag
    52261 ttcagccact ttgcgacttt cttcttcacc aaatccacgt gcagtaatag ctgctgctcc
    52321 gatacgaatc ccacttgtct tgaatggtga caaggtttcg taagggattg aatttttatt
    52381 tagggtaata ttgacttcat ccagcaagtt ttgagcaact tttccgtttt ctacaacctt
    52441 agtcacatca acaaggaaga gatggttttc agttccacct gaaataatac ggaaatcagg
    52501 gtcttgcaag aagacatctg ccatagcctt gctgttctta attacattgg cagcatattc
    52561 cttgaaagct ggatccaaaa cttctttgaa ggaaactgcc ttagcagcca caacatgctc
    52621 caaaggacca ccctgaatac cagggaaaat agctgaattg attttcttag ctaaatcctc
    52681 atcattggtc aaaatcaaac caccacgagg accacgaagg gttttgtggg tcgttgttgt
    52741 agtgatatga gcgtatggca ctgggcttgg gtgaagacca gctgcaacca agccagcgat
    52801 gtgggccata tcaaccataa gcttagcccc aacagcatct gcaatttcac ggaattttga
    52861 aaagtcaata atttgagaat aggctgaagc accagctaca atcagttttg gttttacttc
    52921 ttgggcttgt ttcaagatag catcaaagtc caaaagttcc gtttcaggat ccacactata
    52981 ggaaagaaag ttgtaggttt gaccagagaa gctaactgga gctccgtggg tcaagtgtcc
    53041 acctgctgcc aaatccattc ccataaccgt atcacctggc tcaatcaagg acatgtaagc
    53101 cgcacagtta gcttggcttc ctgaatgtgg ttggacattg gcaaatttag caccgaaaat
    53161 ttcttttgcg cgttcaatag caagagtctc tacaacgtct actacatcag ttccaccata
    53221 ataacggcgt cctgggtaac cctcggcata tttatttgtc aagatagacc cttgagctgc
    53281 cataacagcc ttggaaacta cgttttccga agcaattaac tcgatattat tttgttggcg
    53341 ttcttcttct ttggcaatag cattccagag atcagcatca tatgctttaa aatcatcttt
    53401 gtcaaaaatc ataggtcttc tcctttattg tgtgactagt ccattagttt gattttacaa
    53461 taagaaaatc aaactaaaag atgcgaataa accgtttctg cattttatca caagtatagc
    53521 caactttttc ataaaatgca tgagcaccca gacgatgatt ggcagaattt aagcggataa
    53581 acccataacc acatcttttg gcttcttgtt ccaacccttg tagtaaactt ttaccgatac
    53641 cttgaccttg cgcttgaggt gaaactgcta aagctaagat attaaatcct gctttggaat
    53701 agagtgattc gtaaacttca gcgtggacat atccaagtaa gacatgatta gctgcatcct
    53761 catagccaag taggaaatga tgggaatcct gagacagtct agctagttgg ctagccgttt
    53821 cctctggact aaaagtataa cccaaagcct cttggttgat gtcacatatc gctttcacat
    53881 ctgtttcttg caaatctctt agcatttcaa gcctcctcaa aagaaatctc tggcaaccga
    53941 gcaagaatat cttctcgttt aattgcgcct tggcgtaaga ttttcacctt gtctccagac
    54001 aaatccacaa tagttgaatc ctgtccagtt agaaaagcat cgtcttccag acccagaacc
    54061 tcttggtcaa aatccttcag aatttgttca aaggttacac cacttgcctg acctgagata
    54121 ttggcagacg gcccaatcaa gggacctgtc tctcgaatta aatccagtgt gatagggtga
    54181 ctgggcatcc gaaatccaat agttgcaagg tcagaattta cccaataggg aactcggtca
    54241 ttggcttcga gaataatggt caagggacct ggcaaaaagg tctctacaag tttttgtaga
    54301 taagctggct gattcttaga aaagtgcaag atatcctcta aagaggcaac attgagattg
    54361 agcgccttgt ctctaggacg acgtttgagc tggtaaacat ggtcaactgc tttttcgtct
    54421 aaggccttgg caaaaagacc ataaaccgtc tctgtaggca gaatgacagc tccaccattt
    54481 tccaactctt gtctaatcct gtccatcatc aaccacgacc atcctatctt gaccaaattg
    54541 gtccttgagt gttcgaactc ttttttcagg aagatgtttc ctaaaaagtt cgggaacact
    54601 ttgaccttgc ttgtatccaa tttcaaggta aatcttacca ccatccttga gatagtcttt
    54661 tgcatcttcc gcaattctac agtaaatagc taggccatcc tcgtctgcaa agagagctag
    54721 atgaggctcc gaatgcaaaa cattcaagcc tacctctgac tcatcttcac gagagatata
    54781 gggtggattg gatacaatta tatcatattt ttcagaaatt tctgcaaaac aatcagattt
    54841 tttaaaaaat atattaagat tttgatcgct agcattctct gatgcaagct ctaaggcctc
    54901 ttgagaaaca tctgctgctg tcactgacca atctggtcta ttttttgcta gagcgagagc
    54961 aatagctcca ctacctgttc caatatccag aactgagaga ttcgtctcaa gattttcagt
    55021 tagaataagc tccactaact cctctgtttc tggacgagga atcaaaaccc gttcatccac
    55081 ctttaaatgc attccataaa aatctgcctg tccaatgatg tactgagctg gcttgtgagc
    55141 tgctagttgc tggtaaatat cttctacaaa ttgtttttct tcctctgttg tcacctcctg
    55201 ctggagggca aaaataaagt ctgtaaaaga tagatttttc agactacgat agacaaaaga
    55261 gaggctttcc gcttcctctc cttgtcttat caactcttct tcaaaatttg aaaataattg
    55321 agctaatttc attatttgtt taattcttct agtttttgtg tttggtcata aagcaccaag
    55381 gcatccacaa cttcgtccaa tttaccagac aaaatcgtat ctagtttttg gagggtcaag
    55441 ccgatacggt ggtctgtgac acggttttgt gggaagttat aagttcggat ccgttctgaa
    55501 cggtcaccag taccgattgt cgacttacgc tcagcgtctt gttcatcctg agcaatctga
    55561 gcaaagtggt cagcgacgcg tgcacggata atcttcatag ccttctcgcg gttcttctgc
    55621 tgggtacgtt cttcctgcat ctcaaccttg atattggttg gcaagtgaac gatacgaacg
    55681 gcagtcgcaa ccttattgac gttctgtcca ccagcaccag aggcgtgata gatgtcgaca
    55741 cgaaggtctt ttggatcaat gtcgtattca acctcttcaa cttctggcat aacaagaact
    55801 gtcgctgtcg aagtatgaac acggccttgg ctttctgtca caggaacacg ttgcacacgg
    55861 tgggcacctg attcatactt aagcttagag tatacagact gacctgaaac catagcaacc
    55921 acttctttaa aaccaccgac accattcata gaggcttcca tgacttcaaa gcgccaacct
    55981 tgggcttccg catacttttg gtacatagtt agcaaatctc cagcgaaaag tgccgcttcg
    56041 tctccaccag ctgctccacg gatttcaagg atgatattct tgtcatcgtt tggatccttt
    56101 ggaaggagca aaattttcag tttttcttca tattcttctt tttcagcctt ggcatctttg
    56161 agttcttgct tggccatttc ttccaagtcc gcatctccgc ctgattcctt aatcatctct
    56221 tcggcatcga cgatattttg aaggacttgt ttatactcac ggtaggctat tacggtgtca
    56281 cgattggaag cttcttcttt tgaaagctcc ataaaacgct tggtgtctga aacgacatca
    56341 gggtcactca gcaattctcc tagttcttca taacggtctt ctacagcttg tagttgatca
    56401 tagatgttca ttttttctcc ttatttctca attgttaaat catagattgc tactacttca
    56461 ttctcggcta tttccccagt ttctttaaat ccataactga ggtaacaaaa tcttgcctgt
    56521 tcattttctg gttcataaga caaccaaagt ttattgctta aacctgctgg cgctgttcga
    56581 acatagtcta gtactttatc cataattggt ttaaaatatc cttgattttg aaaattccta
    56641 tcaatcataa aacgaaatag taaataattt ccactactaa ttccgatctt tttatcataa
    56701 gctatcatca caaaacctat aattgcatca ttatcataaa ctgccaatgt agctacaaaa
    56761 tctccatttt tagtgtagac gtatgcttca gctaaactaa ttgcgttggt tgcaatgaat
    56821 tgtttttgat attccttgac atccaaattt aaaacatcaa aataattttc cattgtaaca
    56881 tctcttagtt caattgtcat agttttgctc cttgttagag gttatcattg gcgtaaaata
    56941 atgtttacgg caaactgaga tataggtttc gttaccacca atctggatct gttctccatc
    57001 gtaaacgggc agtccatcct gtgttcgcaa caccatggtc gcctttttct tgcaatactg
    57061 acagatggtc ttgatttcgt caatcttgtc tgctaaaagc aagagatatt tggaaccttc
    57121 gaacaattca ttgcgaaagt catttttcaa gccaaaagcc atgacgggta tgtctaactc
    57181 gtccacaaca cgagctaggt cgtaaacatg gtggcgttta agaaactggg cttcatcgac
    57241 caaaacacag taaggttttt ctggtaggtc tcggatatag ccaaagatat ccgttgtttc
    57301 ctcaatcgca agggcagggc gtttcatgcc aattcgactc gacacatagc caacaccgtc
    57361 acgcgtatcc agagccgagg tcataatgac aacacctttt ccttgctcct cgtagttata
    57421 ggccactttg agaatctcaa tcgttttacc agagttcatg gtcccataac gatagtacaa
    57481 ctgtgccatg tttcttgctt cacgtccatt tctaaatttt tgctacattc tagtatatca
    57541 taattttctt aagctttaaa cggcaaaatg tggtaaaatg gaagaaatca aaactagtgg
    57601 aggaagctat tatgccattt gtacgcatcg atttatttga aggacgcacg ctcgagcaaa
    57661 agaaagctct tgctaaggaa gtaacggaag cagttgtccg caacactgga gcccctcaat
    57721 ctgctgtcca tgtcatcatc aacgacatgc cagaaggaac ttacttccca caaggggaaa
    57781 tgcgtactaa ataagctagc ttaagcagaa ttgcttaggc tttttcaatc tccaagtagc
    57841 attcattgaa gaaatatcct aaatttgtta caatttgaaa agaaacttgg agaatttcca
    57901 agaaaagagc tattaattaa aggaaacatt atgattacac gtgaatttga taccatcgct
    57961 gctatctcta ctccactagg tgaaggggct attggtattg tccgcctgag cggaacagac
    58021 agttttgcta ttgcgcaaaa gatttttaaa ggaaaagact tgaacaaggt tgccagccac
    58081 actctcaact acggtcacat tattgatcct ctgactggta aagtcatgga cgaggttatg
    58141 gttggggcta tgaagtctcc aaagaccttc actcgtgagg atattatcga gattaacacc
    58201 cacggtggga ttgcggtgac caatgaaatt ctccagctag ctattcgtga aggggctcgg
    58261 ttggcagaac ctggtgaatt taccaaacgt gcttttttaa acggtcgcgt agacttgaca
    58321 caggcagagg ctgtgatgga tatcatccgt gccaagactg acaaggccat gaacattgcg
    58381 gtcaaacaat tagacggctc cctttctgac ctcattaaca atacccgtca agaaatcctc
    58441 aatacacttg cccaagttga ggtcaatatc gactatcctg aatatgatga tgttgaggaa
    58501 gctactactg ccgttgtccg tgagaagact atggagtttg agcaattgct aaccaatctt
    58561 cttagaacag cccgtcgcgg caaaatcctt cgtgaaggaa tttcaacagc tatcatcgga
    58621 cgtcccaacg ttgggaaatc cagccttctc aacaacctct tgcgtgagga caaggctatc
    58681 gtaacagata tcgctgggac aacacgagat gtcatcgaag agtacgtcaa catcaatggt
    58741 gtacctctca aattgattga tacagccggt attcgtgaaa cagatgacat agtggaacaa
    58801 atcggtgttg agcgttcgaa aaaagccctc aaggaagccg acttggttct actagtgcta
    58861 aatgccagtg aaccactgac tgcgcaagac agacaacttc ttgaaattag ccaagatacc
    58921 aatcgcatta ttctacttaa taaaaccgac ctgccagaaa cgattgaaac ttcgaaacta
    58981 cctgaagacg ttatccgtat ttcagtcctt aaaaaccaaa acatcgacaa gattgaagag
    59041 cgaatcaaca acctcttctt tgaaaatgct ggcttggtcg agcaagatgc tacttacttg
    59101 tcaaacgccc gtcacatttc cctgattgaa aaagcagttg aaagcctaca agccgttaat
    59161 caaggtcttg agctggggat gccagttgat ttgcttcaag ttgacttgac tcgtacttgg
    59221 gaaatcctcg gagaaatcac tggggatgct gctccagatg aactcatcac ccaactcttt
    59281 agccaattct gtttaggaaa ataagaaaaa tccatgatcc ttcattcggt catggatttt
    59341 attgtcttta ttagtaatct ggtcttaaga cccctgttac agttgcctta gttgcttcgt
    59401 agtcgccatc tacgacaacc ttgataatgc gtttggcatc ttcttctggt gctggaacaa
    59461 gaggtagacg agtgggtcca gcttcaaatc ccatatagtt aagaattgcc ttaactggag
    59521 caggacttgg ataagagaag agagcattaa ccttaggaat gaatttacgc tgaattgctg
    59581 cggctttctt catatcgctt tctgcaatgg cagtaaacat ctcgtgcatt tcatccccat
    59641 ttgtatgaga ggcaacagaa ataaccccat ccgccccaag gttcatggca tggaaagcat
    59701 ctccatcctc acctgtataa atcaagaact cttcaggctt gtgctcaatc aagtaagcca
    59761 tattagccaa gctagtacat tctttgacac cgataatatt tggatggtca gccaagcgaa
    59821 gcatggtttc tggagtcaat tcgacaacta cacgccctgg aatgttatag ataataattg
    59881 gtaggtcaga agcatctgca atagtcttaa agtgctgata catcccttct tgagaaggtt
    59941 tgttgtagta aggaacaata gcaagcccag ctgcgaaacc accaaattcc gctacttctt
    60001 tgacaaactc aatagagtca cgcgtatcat tagtacctac acccgcaatc aaaggaacgc
    60061 gtccattgac aaccttttgt acagccgcaa acaactccaa ctcctcatcg tgggtcaaag
    60121 ttggactctc agcagtcgtt cctgcgagaa gaattccatc cgtatgatgg gccaataaat
    60181 gctcaatcaa ggctggaata gcatcaaagt taatggaacc atcctcatgg aagggggtaa
    60241 taaaggctgt aatgatttta cattctttta aatcttgata agacacgaaa acacctctct
    60301 atttcaaaga aggagttcat ctgaactcct aaacgatatg actattttaa ttcaaatttc
    60361 aattcggctg ttggacgaac caatccacgt tcatgaagag tttcagcaat ctgaactgag
    60421 ttccaagcag cacctttgag aaggttatct gaaacaaccc acatgtgaat tcctttttct
    60481 gcatccaagt ctttacggat acgaccaaca aaggtatcac gcgaaccaac tgcattgata
    60541 gcttgaggat agatttgatg agctacatca tcttcaagaa cagcacctgg gaaggctgcg
    60601 atagctgctt ttacttcttc gattggagcc acttcttttg tttcgatata aacagactca
    60661 gagtgagctg acaagactgg aatacgcaca catgttgcag atactgcaat gctatcatct
    60721 tccataattt tcttagtttc cttggtcatc ttcatctctt cgtacgtgta atcattatca
    60781 gtgaaaacat caatttgtgg aagagcgtta aaggcgatag gataatgttt cttgtcacca
    60841 cctgaaggca agatttccgc atgcaaatca cgtggtttca caccatcatt caaaacctca
    60901 cgaagttcac gttgtgtctc aagaattgct cccataccag cacctgaaac ggcttgataa
    60961 gttgaaacaa tgatacggtc caagccccat ttttggcgaa ccggctcaag agccaccatc
    61021 atttggattg ttgaacaatt agggcaggca atgattccgt tgtgagcatc aagtgcatga
    61081 gcattgacct ctggaacaac caaaggaaca tctggatttt gacggaaata agatgtatta
    61141 tctactacta ccacgccagc ttttactgcg tatggtgcat acttagctga tgtagaacta
    61201 cctgctgaaa agagagcaat atcaactcct tcaaaagctg tttcagtcgt ttcttcaatt
    61261 gtaatatctt gatctttaaa tttcaatgac ttacctgctg aacgtgcaga agcaaggtaa
    61321 cgaattttat cgattggaag tgttgattct tccaacattt ttatcatctg agcaccgaca
    61381 gcacctgtcg cgccgactac agcaactgta tatcccataa ataacctctt tcggaatttt
    61441 ctaaaaattt ctataataga agtattatac tactttttcc atgaattgca aagctttttc
    61501 atcatttttt ggaaaataaa aatcccagtc gctagactag ggactaagag gcatcttcat
    61561 gtgatgagca ggttcacaca actcatcaag gtccgctcct gcgttatgac ctccttatgc
    61621 tcaatagtag tccgaagact acctatcgac tcatcgcata ttctatatta ctagagatac
    61681 ttgattttgt caataagaaa ttttttcgat cgagtataac aaaaaactct cgtattcaag
    61741 agtttcccta tacatatcat gctaattgcc gggattgaac cggcgacctc atccttacca
    61801 tggatgcgct ctgccaactg agctaaatca gcttacttaa gaagtatact atattcagaa
    61861 aaacttgtca agtttcctta gaaattttcc ataggaaaaa gccaggtaag aactacctag
    61921 cttatcttct tctatttact taaatcaatt cgacgaccaa ttttaccaat aataatcgcc
    61981 ccaataatca atgaagcaaa ttcaccgatt cctgttgtaa accaagtaag gaagaatggt
    62041 aattctgcta caatatttaa ctctgcagcg atagtaaaca tggaaattga aaagaggatt
    62101 gaaaagaaga aatgatcttt tcgaatcaat ccgttaaaga ggtaatcctt gctatatttt
    62161 gcaaaaagcc aaacacctaa actgaggaat actaaggttg aaccaccacc aacaaagaca
    62221 tctagcagtc cgaagctaaa gaaattagca atcatacaac cgatggtaac tccgatgatg
    62281 tacttaggat tgtaaaaagc cataaagttc atcatttctg aaatacgaaa ctgataagca
    62341 ccatagctga tggcatttag gggcggtgtg acagtcaaaa cgacgtagat agcagcgacg
    62401 attgcaatat ctgcaacatc acgaatagtt aattttttca tcttttctcc tttggcggtt
    62461 gcccgcgtgt aatatgcttg gtgaaagaag ctaagcacca agggttgctt tattcaaccc
    62521 tactagtata gcacaatagc ctgctttatg ctatacttaa cacatgaaaa ttcctattca
    62581 aaaatttttt aacaatgaaa tcttagccta tctctttttt ggccttgcga caactctagt
    62641 ttcgattctc tcacgactag tcatttatca actaagtcat caggaactcc tggctactgc
    62701 cctagcaaat attatcggta tcctatttgc ctttatcaca aatgatacga ttgtatttaa
    62761 gcaaaaaaag aaaaatagac ttatccgttt agtgaaattt tctcttgctc gcctttctac
    62821 ttttctgtta gacttgtttt taacttttct ctttgtaacc caatttcctc acattatagg
    62881 gcaattcgta actgaaaaca ttgataagat aaatgctatt gaaacaataa ttgcacaaat
    62941 attcattatt atcatcaatt atatcttgag caaggcctat atttttagaa aataatgctc
    63001 catttatgag ccttttaatt gccttctata atgatttagg atacaatgaa acacgaaaca
    63061 ttgaaaggaa aacagtatgt taaaaaatct aaaatcgttc ttgcttcgag gaaatgttat
    63121 tgaccttgct gtcggtgttg taattgcctc tgcttttggt gctatcgtta cttcacttgt
    63181 aaacgacatt atcactcctc ttattttaaa tcccgctttg aaagctgcta aagttgaacg
    63241 tatcgctcaa ctttcttggc atggagtcgg ctatggtaac ttcttaagtg ctattatcaa
    63301 ttttatcttt gtgggtaccg ccctcttctt tattatcaag ggcattgaaa aagcacagaa
    63361 actgactggc ataaagaaag aaaaaactgc cgaaaaaaaa ccaaccgaat tggaagtcct
    63421 tcaagaaata aaagctctcc ttgagaaaaa ataatcgatt aaaaggatct agcgcaaagc
    63481 taaatccttt tttctttact ctttgggtaa cttgcctgct ttttcaagca tttttttgat
    63541 cagataaggc atcttaacat tctcccgccc ttttttctca atcagttttt tcacaaattc
    63601 tggcatttgt aaatcttcag attcagctaa aatgtttttc gtctcgtctg aaggaactaa
    63661 ctcatcaaag gtctcttctt ctgggagaaa ttccttaaac tcttgatttt cattgactct
    63721 aactgtattg accaaagcat caatcaaacg agaatctgta tttggcattg gtgaacgatg
    63781 gtagtttacc ccaaattcct ggcataagtc ataacattct acatcattgt caaacaagac
    63841 ctcaatatgc tcactgatga aactaatagg tacaaaaata taatggtctg gatgttctgt
    63901 ctgttctctg agatactcca aaacatctgg tttaatccat ggaataccaa tatcactctc
    63961 actctgccaa gtgttggtat attgttctga actcaagccc agtttttcag cgactagctt
    64021 gctattttcg aaaatttggt ctatataagg atcaccaaag tccaaggcaa aaatgggcac
    64081 actatgggct gaaaagatga ctttaaaact gtcttgcttt acttcttctt ttaaaatctt
    64141 agcaatttca tctgcccaat agtttaagag cacttcttcc tgataccagt ccttaatgac
    64201 caaaaattga atttgtttgc tttctaaaaa tttttcatag cccatgacag agtagaaaga
    64261 ataatggggc tccaaaatca agcaaataca ctgttcaatt ccgtctgctt ccatttgacc
    64321 gatcacatct ggaataaagg gactggaaaa cttattagca aagtagacac tgtattcatt
    64381 ccccagccta gcttctacca aggtaacctc ttgacgggta attttttgca gaggcgtgcc
    64441 tccaattcgt acataattat catagagagt ctgaatctcg tggtcttggg gtctcacccc
    64501 acgacgaata tttgtgaaaa aatcagctac accttcaaag gtaatctctt ctggtgaacc
    64561 gaaggtcatc attaaaattg cttttttcat gactgcttcc ttgtgatgtt tttatcaagt
    64621 ttattttatc attaattcat cgataagtaa acgctaacat agggacattc tcaatcttct
    64681 gtcttttgtt tttctcttct ttctatgata caatggaaaa aataaattca aaaggagttt
    64741 ttttatgact tatccaaatc tcttggaccg cttcttaacc tacgttaagg tcaacacgcg
    64801 ctctgatgaa cactctacta ctactccaag tacacagagt caggttgact tcgcaacaaa
    64861 tgtcctaatt cctgaaatga aacgtgttgg actgcaaaat gtttactatc taccgaatgg
    64921 ttttgctatt ggaaccttgc cagccaacga tccgtcttta acacgtaaga ttggttttat
    64981 atcgcacatg gatactgctg attttaatgc tgaaggagtc aatccacagg taattgaaaa
    65041 ctacgatggt ggtgtgattg aactagggaa ttctggtttc aaactcgatc cagctgactt
    65101 caagagtctt gaaaaatatc caggacaaac gctcatcaca acagatggaa caaccttgct
    65161 aggtgctgat gacaagtcag gaattgctga aattatgaca gccattgaat atctaactgc
    65221 tcatcctgaa attaagcact gtgagattcg tgttggtttt ggtccagatg aagaaatcgg
    65281 tgttggtgcc aataaatttg atgcagaaga ttttgatgtg gattttgcct acactgttga
    65341 tggtggtcca ctaggtgaac ttcagtacga gactttctca gccgctggtg ctgaattgca
    65401 tttccaaggc cgtaatgtcc accctggtac tgccaaaggg cagatggtca atgcccttca
    65461 gctagcaatt gattttcata atcaacttcc agaaaatgac cgacctgagt taactgaagg
    65521 ttaccaaggt ttttaccatc taatggatgt gacaggtagt gttgaggagg cgcgtgcaag
    65581 ctacatcatt cgtgattttg aaaaagatgc ctttgaagcg cgtaaagcat ccatgcaatc
    65641 tatcgctgat aagatgaatg cagaacttgg gagctaccgt gtcactctca acttgacaga
    65701 ccagtactac aatatgaaag aagtcattga aaaagatatg actccaatta ccattgctaa
    65761 agccgttatg gaagatctag gtatcacgcc tattatcgaa ccaatccggg gtggaacaga
    65821 cggctctaag atttccttta tgggaatccc aactccgaat atctttgcag gtggcgaaaa
    65881 tatgcacgga cgttttgaat acgttagcct tcagactatg gaacgtgcag ttgataccat
    65941 cattggcatc gtagcttata aaggctaaaa agacgaggta gctcagctac ttcgcctttc
    66001 tttttattct actggttttt cttgatttcc agtagttgta gaagattctg ttgtttcatt
    66061 ttctgaagtt gattcagcag gtttagaatc tcttgtattg cttggtttgt tttcgtcgct
    66121 agcaatttca atgttagatt ctgcagttgc gtttggttgg ttctcagcac tggtgttatc
    66181 actatttgct tcagcatttc ttgctggact tgtttcttca cttgcgctag cttttgactg
    66241 gatttgatga ttcaaaacta gaatagcttt tgtcgattca agtaaagctg ttttgtcttt
    66301 actcttagca gaaagttgat ctaataatgc atccacctta tcaaagtccg catcagatcc
    66361 attattactt tctaaataag agtgaagcga catgagaata tcgtagagtt tttgatagag
    66421 tacaagtgtc tgagaatctt gctcagcatt ttccttttct tgttgaaggg cgctagcgat
    66481 acgagtcaag acatctttta cctgactgtt tacttcatcc aagtctgcat cagccttgtt
    66541 tgtggcagct tttagatttt ctacttcttc tgccaaggat tgtctgattc cttcttcatg
    66601 gatttgttcc aagagttgat ttaccttgct caaaagactt tctacttctt ccttgctatc
    66661 tgtcgcagat tattggttgc catctaccat gtactcctaa aacaggagag ttataatcca
    66721 agattacaag gccttacaga aataagaaat ccagataaga caatgttcgt ccaagacgct
    66781 attcgcttcg cacagcagca cggattcaat atgctttaat tttaaagttt aggtgtcaag
    66841 acctcttttt agtgtgccca aaatttagag aagtaatcaa tcaactaact tttatttttt
    66901 tcaaactttc agtaaactga cctaaagcta actcaatctg tctttgtaga tgcttctgct
    66961 atcagctaga agttgatcta cttttgccaa gactgccttc tcatcaaaag ttccaggttg
    67021 atagttggat tgcagggatg gaatcttgtt tttcaaagcc gcttcatatc ccttagtttg
    67081 aaccttgatg tagtgattgt ggtcgccatg aggaatcaca aaaccttctg aatcttcact
    67141 tataattcga ttggcatcaa aaccatgacc atcttcttcc tcatgatgga catgtagtga
    67201 cggattactt aatacagaac tagaagaact tcctacctct tccgtgttag agtgtgatgg
    67261 gggattgtta agagatgact taggaatata gtgatagtga tccccatgtc ttactatata
    67321 agcatcacct gtatctctga caatatcatt agggttaaag acatatgtgg ctgctaattc
    67381 acctgccgac aagtcactct caggaatgaa atgatagtga ccaccatgtg gtactatagt
    67441 agattgaaat agaatatgag caaattgata aggggatttt aaagtaattt ctaacaatga
    67501 tttagaaact atgatgtgct attctaaatt caactcacta tatataacca tcatcggtag
    67561 tataacgtcc ctgtaatttt gctacagata cttctgcact agctccttta tcgtctttac
    67621 catgttcttg tttttggcga ttgatttcat cttttgttcg tacattttct gcatgagctt
    67681 gatctttaag gtaaacataa tactttccat ctaccttaat aatatatcct cccttaacct
    67741 aactgacgat atcttgatct ttcggctgat agttgggggc tttcattaat agctcttcac
    67801 taaagagcgc atcaaaagga actttaccat tatagtagtg ataatgatcg ccatgagaag
    67861 ttacataacc ttgatctgta atcttaataa caatttgttt tgcttgaatt ccttcttttt
    67921 gactaaccta gtctggagtc aaattttcag tcttcttagt gtctttatta ctgtttacat
    67981 atgaaacacg atttttatct gtattggcct gttagctatg ttggttcaga gcataaacac
    68041 acagacttaa ggaaaggata acaacagatc cagctgctat atatttcttt ttaaatttca
    68101 taattacctc atttctataa ttatttatat gatgtcttca ttattaaatg attaaataaa
    68161 ttaattaacc aattaattaa ctagtaaata ttccacctct ttttaagttg tatgtcaaga
    68221 aattttatat attaataata aaatgaaatt ctcccaaagt cagagtttta tttctaactt
    68281 ttgagagaac ttcatttttg attcagactt tttctactgc tattccttac gctatgagat
    68341 cagataaatt cttttttatc acttctccac ttggcaatct taattcaatc gttccatcca
    68401 tattgaatat aacactatct aagcctaatc cgtaactagc tgtaaatttt tctaattttt
    68461 cttgtacagg atctactgct ggagcttcct ctaatgctgg atctaacata gggtcactcc
    68521 ccacattccc ttctggattc aacattccat tatccgttga gttttctggt tttacaggtt
    68581 tttcgtttgg tgcctctggt aaagaatctg ctggtttatt ttctgttggt tggttctcaa
    68641 ctgttccagt agatactttt ccagtttcag atggtttatt ttcaccattt ccttgaggtg
    68701 cttctcctgt aaaatctgcc atattctttt taatgacttc tcccgatggt aaatataatt
    68761 caattgttcc gtccatatta aacaagacat tttctagctt catcccataa ctttcagcaa
    68821 attttgctac tttttcttgt acaggatcca ctgtaggaac ttcttctaac gttgaatcac
    68881 tagtactgtt cccagtttca ggaagctttt ctttttctac cttctcacta gtctttggtt
    68941 cttctacctt ttcatcaagt tttgagtttt cttgtgcttt attcctttta aattgtggta
    69001 gaatacttgg tttatcagtt tgattttctt tttccaagat aggtacttcc acaatataag
    69061 tcgattgatt gtccaaataa gcatttgcca tgaaggttac aggaatttta tttccggccg
    69121 ttctggttgt tccttggttt aatttcggaa tcggtaattt aatttcacca actttatagt
    69181 tattttctaa ataagcattt ccatgaaatt catcaaacac tctgactaaa gcatcagttc
    69241 ctttaggcac tgcaaattga gggttcactc ttaaataagt atcccctgca tggaaaggat
    69301 agaaaatcgt ttgactggcc attttgtaag ctaaagaggt tggaactgta aatgtaccat
    69361 cataacttac ttctggataa tcttttgaag cgatagtata cttaaatgtt tgtcctggta
    69421 aataaggttg atctaattca aagtttgcaa tattccctac tccttctcca aatactttac
    69481 cagatacttt ctccaatact tttccatctg gtgttattaa ttttactagc atattgatac
    69541 ctaatttttt ttccaattca ggcggaaaac taaaagaaac gcgtttttga ccattggcta
    69601 gagtaaagtt ttgattatta aacgtactat tttttaacaa attaacaaca ttcgttaatt
    69661 cttctccagt ataaacttta ttcccttctt ttttagcaac tccttcttcg ggtttaaaca
    69721 gttcatagtt actgtgagaa tgaccaattc caaccggttt atgttcatca atcggatctg
    69781 catgatggtg atctccatgc ggataaataa tcgcattttt ttctttattc acgacaatac
    69841 tttcacgttt gacaccatat tgtttcataa tgccagcaat tttttcttcg atttttttat
    69901 ctaaatcttt catttctttg gcattacctg gataatcctg ttcatgagat gacaaagaat
    69961 ctaatccatt atgactagtt ttaacttcct ctaaatgttt ttgcgcagcc ttaatttgct
    70021 cttctgtcaa gtccttcttg aagaaataat gattgtggtc tccgtgactc atgacaaaac
    70081 ctgattcatc ttcagcgata atacgattag catcaaatcc gtatccatct tcttcatgtt
    70141 tctcatgtga agttcctgga ttgattggaa gagatggaga aggtgttgct agactattgt
    70201 ttggaagagt cggttgccca atttgatttg attttggaat gtaatggaaa tgatcaccat
    70261 gtcttacaat ataagctgta gccgtttctt caacgatatc ttttggatta aaaatataac
    70321 catcagatgc tgaagagagt ttcttacttg tcgttaaaga agaaggattg cttgaaagac
    70381 tgcctagact agacactact tcattaggtt ttgcatttgt agaaactgta gaaccagttc
    70441 cactgatagg caccattctg gcaatctttt cttctaaggc agaaagcttg ctgtaaggaa
    70501 taaagtggta atggtcgcca tgcggaatcg caactccatt tggtgtacga ctgataatct
    70561 tagcagggtc aaagaccagg ccatctgatt cactgtaacg ttgggcgcta ggtgaatcat
    70621 agagttcctt caaaagactc tggagatttt cagatttatt tgctggcttg ctagttgatc
    70681 cttttgctac agattgcgtg ttattgtcac tagctgttga agaatagctt aactgactcg
    70741 gttgcatatt ttttccagcc agatgtgctt tagctgctgc taattcacta gcagataaat
    70801 cgcttttggg aatgtagtga tagtgacctc catgaggaac gatataagca ttacccgtat
    70861 cttcgataat atcagctgga ttaaagacat aaccatcatt tgtcgtatat cgtccctgag
    70921 accttgctac agcaacatta gagttaacct tctcattatc tttgacatgt tcttgttttt
    70981 gacgattgat ttcatcttta gttcgaacat tatcagcatg agctgcatct ttcaggtaga
    71041 cataatattt tccatcgacc ttgatgatat aaccaccctt gacttcattg acaatatcag
    71101 cgtctttaag ttgatagttt ggatccttca tcaagagttc ttcactaaag agggcatcat
    71161 aaggaacttt cccattatag taatgatagt ggtcaccgtg tgacgttaca tagccctgat
    71221 ctgtaatttt gattacaatt tgctcagcct gaattccttc tttctggcta acctggtctg
    71281 gtgtcaagtt ttcacttttc tgacttgact ggctgccatc cacataagag acacgattat
    71341 tgtccttatt ttcctgcgaa cgatgctggt ttagtgcata ggcacataga ctcaaggata
    71401 cgataacagc tgatccagct gctatatatt ttttactaaa tttcataaat ccctcatttc
    71461 aataaatgat gaagtttttt tctcaacttc ttttacttta ttaaatagtt ttctaaaccg
    71521 attatttaac catttaatta accagtaaat agtctactat ttaaaattac ttttgtcaag
    71581 tttctgttac gtttttctaa aaaagagaag taacacgaaa ggttacttct ccataaaata
    71641 tgctccattc attttactac tgtataggag ccggttgact ttcttttaac aaagccaaga
    71701 gactatctac ttctgctgaa atagtattat tatctttcgt tccgagaaga agactacttt
    71761 ttagaccagt caatgtctcc atagcatttt gtctaatact agaatctgtt actttttcta
    71821 gcaaggcctc cgcctctgct atcttagcgt taataacaga atgctctact tgaggaattt
    71881 cagcctcatc tgtagtatct tcagcttctt cctctgtctc ttccgtatca gtgcttggtt
    71941 tataaagatt atctgctgaa ggatttaaac cagcgtgatt ctctttttca tcagattcag
    72001 ggtgagttgg ctcacttact tcatcatgtt ccttatcttc ctcaggtttt tctgtctgag
    72061 gtttctccgt ttgattggta tcagcttgac catttttgtt tctttgaaca tggtcgctag
    72121 cgttaccaaa accattatct gaatgcggac gttcgtttgg atgttcgaca tagtacttga
    72181 cagtcgccaa aagatcctca agagtatacc ccttaggtgc ctcataaagg ccttcgtcaa
    72241 accactcaaa tttgatgtta tggtaatggt cataatgagg tatgattaaa ctaccgtttt
    72301 tgacttctac agtatattga agattgtaag gcacacgatc aagtggcacc ttcttagctg
    72361 ctttcacgcg gttgtagata gcttctgctc cttttgcctc agtatttcct gaatcctgat
    72421 g
//
LOCUS       DAVBOD010000003        68162 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 640-05
            SAMEA1012484-rid20186543.denovo.003, whole genome shotgun sequence.
ACCESSION   DAVBOD010000003 DAVBOD010000000
VERSION     DAVBOD010000003.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012484
            Sequence Read Archive: ERR059358
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 68162)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 68162)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979948.1
            Genome Coverage       :: 595x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:03:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,266
            CDSs (total)                      :: 2,219
            Genes (coding)                    :: 2,091
            CDSs (with protein)               :: 2,091
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 71 of 128
            Pseudo Genes (incomplete)         :: 50 of 128
            Pseudo Genes (internal stop)      :: 33 of 128
            Pseudo Genes (multiple problems)  :: 22 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..68162
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012484-rid20186543.denovo.003"
                     /strain="NIG 640-05"
                     /db_xref="taxon:1313"
     gene            <1..116
                     /locus_tag="VQ862_000154"
     CDS             <1..116
                     /locus_tag="VQ862_000154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HET3114567.1"
                     /translation="TPEQAKQILEYGVRGIVVGGAITRPKEITERFVASLK"
     gene            135..1652
                     /locus_tag="VQ862_000155"
     CDS             135..1652
                     /locus_tag="VQ862_000155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000477452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HET3114568.1"
                     /translation="MFKVLQKVGKAFMLPIAILPAAGLLLGIGGALSNPTTIATYPIL
                     DNSIFQSIFQVMSSAGEVVFSNLSLLLCVGLCIGLAKRDKGTAALAGVTGYLVMTATI
                     KALVKLFMAEGSAIDTGVIGALVVGIVAVYLHNRYNNIQLPSALGFFGGSRFVPIVTS
                     FSSILIGFVFFVIWPPFQQLLVSTGGYISQAGPIGTFLYGFLMRLSGAVGLHHIIYPM
                     FWYTELGGVETVAGQTVVGAQKIFFAQLADPAHSGLFTEGTRFFAGRFSTMMFGLPAA
                     CLAMYHSVPKNRRKKYAGLFFGVALTSFITGITEPIEFMFLFVSPVLYVVHAFLDGVS
                     FFIADVLNISIGNTFSGGVIDFTLFGILQGNAKTNWVLQIPIGLIWSVLYYIIFRWFI
                     TQFNVLTPGRGEEVDSKEISESADSTSNTADYLKQDSLQIIRALGGSNNIEDVDACVT
                     RLRVAVKEVNQVDKALLKQIGAVDVLEVKGGIQAIYGAKAILYKNSINEILGVDD"
     gene            1777..3105
                     /locus_tag="VQ862_000156"
     CDS             1777..3105
                     /locus_tag="VQ862_000156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000672126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter substrate-binding
                     protein"
                     /protein_id="HET3114569.1"
                     /translation="MKFRKLACTVLAGAAVLGLAACGNSGGSKDAAKSGGDGAKTEIT
                     WWAFPVFTQEKTGDGVGTYEKSIIEAFEKANPDIKVKLETIDFKSGPEKITTAIEAGT
                     APDVLFDAPGRIIQYGKNGKLAELNDLFTDEFVKDVNNENIVQASKAGDKAYMYPISS
                     APFYMAMNKKMLEDAGVANLVKEGWTTDDFEKVLKALKDKGYTPGSLFSSGQGGDQGT
                     RAFISNLYSGSVTDEKVSKYTTDDPKFVKGLEKATSWIKDNLINNGSQFDGGADIQNF
                     ANGQTSYTILWAPAQNGIQAKLLEASKVEVVEVPFPSDEGKPALEYLVNGFAVFNNKD
                     DKKVAASKKFIQFIADDKEWGPKDVVRTGAFPVRTSFGKLYEDKRMETISGWTQYYSP
                     YYNTIDGFAEMRTLWFPMLQSVSNGDEKPADALKAFTEKANETIKKAMKQ"
     gene            3358..4224
                     /locus_tag="VQ862_000157"
     CDS             3358..4224
                     /locus_tag="VQ862_000157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001209417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HET3114570.1"
                     /translation="MRETVISYAFLAPVLFFFVIFVLAPMVMGFITSFFNYSMTKFEF
                     VGLDNYIRMFKDPVFTKSLINTVILVIGSVPVVVLFSLFVASQTYHQNVIARSFYRFV
                     FFLPVVTGSVAVTVVWKWIYDPLSGILNFVLKSSHIISQNISWLGDKNWALMAIMIIL
                     LTTSVGQPIILYIAAMGNIDNSLVEAARVDGATEFQVFWKIKWPSLLPTTLYIAIITT
                     INSFQCFALIQLLTSGGPNYSTSTLMYYLYEKAFQLTEYGYANTIGVFLAVMIAIVSF
                     VQFKVLGNDVEY"
     gene            4240..5079
                     /locus_tag="VQ862_000158"
     CDS             4240..5079
                     /locus_tag="VQ862_000158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HET3114571.1"
                     /translation="MQSTEKKPLTAFTVISTIILLLLTVLFIFPFYWILTGAFKSQPD
                     TIVIPPQWFPKMPTMENFQQLMVQNPALQWMWNSVFISLVTMFLVCATSSLAGYVLAK
                     KRFYGQRILFAIFIAAMALPKQVVLVPLVRIVNFMGIHDTLWAVILPLIGWPFGVFLM
                     KQFSENIPTELLESAKIDGCGEIRTFWSVAFPIVKPGFAALAIFTFINTWNDYFMQLV
                     MLTSRNNLTISLGVATMQAEMATNYGLIMAGAALAAVPIVTVFLVFQKSFTQGITMGA
                     VKG"
     gene            5351..5803
                     /locus_tag="VQ862_000159"
     CDS             5351..5803
                     /locus_tag="VQ862_000159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000575445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HET3114572.1"
                     /translation="MIFDDLKNITFYKGIHPNLDKAIDYLYQHRKDSFELGKYEIDGD
                     KVFLVVQENVLNQVENNQFEHHKNYADLHLLVEGHEYSSYGSRIKDEAVAFDEATDIG
                     FVHCHEHYPLLLGYHNFAIFFPGEPHQPTGYAGMEEKVRKYLFKILID"
     gene            5900..6244
                     /locus_tag="VQ862_000160"
     CDS             5900..6244
                     /locus_tag="VQ862_000160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000254916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3114573.1"
                     /translation="MVSSKHAARASFLDGQGITVDEMSWIINGIVNALIGRYIKLGTY
                     AAKYGISIARSILSRAAATAAARVGLLTKISGWILRVAVNVADVYGNFANNIAAAWDA
                     YDKIPNNGRINF"
     gene            6528..7172
                     /locus_tag="VQ862_000161"
     CDS             6528..7172
                     /locus_tag="VQ862_000161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000057467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HET3114574.1"
                     /translation="MAQKGVSLIKAAFDTDNFLMRFSEKVLDIVTANLLFVVSCLPIV
                     TIGVAKISLYETMFEVKKSRRVPVFKIYLRSFKQNLKLGLQLGLLELGIVSLSLLDLY
                     LFWGQTALPFQLLKAICLGILIFLTIVMLASYPIAARYDLTWKEILQKGLMLASFNFP
                     WFFLMLAILVLIVMVLYLSAFSLLLGGSVFLLFGFGLLVFIQTGLMEKIFAKYQ"
     gene            7341..8258
                     /locus_tag="VQ862_000162"
     CDS             7341..8258
                     /locus_tag="VQ862_000162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrodipicolinate synthase family protein"
                     /protein_id="HET3114575.1"
                     /translation="MSDLKKYEGVIPAFYACYDEQGEVSPERTRALVQYFIDKGVQGL
                     YVNGSSGECIYQSVEDRKLILEEVMAVAKGKLTIIAHVACNNTKDSMELARHAESLGV
                     DAIATIPPIYFRLPEYSVAKYWNDISSAAPNTDYVIYNIPQLAGVALTPSLYTEMLKN
                     PRVIGVKNSSMPVQDIQTFVSLGGEDHIVFNGPDEQFLGGRLMGAKAGIGGTYGAMPE
                     LFLKLNQLIADKDLETARELQYAINAIIGKLTSAHGNMYGVIKEVLKINEGLNIGSVR
                     SPLTPVTEEDRPVVEAAAALIRETKERFL"
     gene            8276..9160
                     /locus_tag="VQ862_000163"
     CDS             8276..9160
                     /locus_tag="VQ862_000163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HET3114576.1"
                     /translation="MTYYVAIDIGGTNIKYGLVDQEGQLLESHEMPTEAHKGGPHILQ
                     KTKDIVASYLEKGPVAGVAISSAGMVDPDKGEIFYAGPQIPNYAGTQFKKEIEESFTI
                     PCEIENDVNCAGLAEAVSGSGKGASVTLCLTIGTGIGGCLIMDRKVFHGFSNSACEVG
                     YMHMQDGAFQDLASTTALVKYVAEAHGEDVDQWNGRRIFKEATEGNKICMEGIDRMVD
                     YLGKGLANICYVANPEVVILGGGIMGQEAILKPKIRTALKEALVPSLAEKTRLEFAHH
                     QNTAGMLGAYYHFKTKQS"
     gene            complement(9176..10027)
                     /locus_tag="VQ862_000164"
     CDS             complement(9176..10027)
                     /locus_tag="VQ862_000164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HET3114577.1"
                     /translation="MDKPDIATIIDSHFEEMTDLEQEIARYFLQAETITDDLSSQQVT
                     QKLHISQAALTRFAKKCGFTGYREFIFQYQHQAENQANQVSKHSPLTKRVLRSYSNMR
                     EQTQDLIDEIQLERIAQLIEDAERIYFFGTGSSGLVAREMKLRFMRLGVVCEALTDQD
                     GFAWTTSIMDENCLVLGFSLSGSTPSILDSLIDAKEMGAKTVLFTSVPNKDSQTYTET
                     VLVATHSQPSYIQRISAQLPMLFFIDLIYAYFLEINRESKEKIFNSYWENKKLNGYRR
                     QKRVRKS"
     gene            10227..12284
                     /gene="pbp2b"
                     /locus_tag="VQ862_000165"
     CDS             10227..12284
                     /gene="pbp2b"
                     /locus_tag="VQ862_000165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 2B"
                     /protein_id="HET3114578.1"
                     /translation="MRLICMRKFNSHSIPIRLNLLFSIVILLFMTIIGRLLYMQVLNK
                     DFYEKKLASASQTKITSSSARGEIYDASGKPLVENTLKQVVSFTRSNKMTATDLKETA
                     KKLLTYVSISSPNLTERQLADYYLADPEIYKKTVEALPSEKRLDSDGNRLSESELYNN
                     AVDSVQTSQLNYTEDEKKEIYLFSQLNAVGNFATGTIATDPLNDSQVAVIASISKEMP
                     GISISTSWDRKVLETSLSSIVGSVSSEKAGLPAEEAEAYLKKGYSLNDRVGTSYLEKQ
                     YEETLQGKRSVKEIHLDKYGNMESVDTIEEGSKGNNIKLTIDLAFQDSVDALLKSYFN
                     SELENGGAKYSEGVYAVALNPKTGAVLSMSGIKHDLKTGELTPDSLGTVTNVFVPGSV
                     VKAATISSGWENGVLSGNQTLTDQSIVFQGSAPINSWYTQAYGSFPITAVQALEYSSN
                     TYMVQTALGLMGQTYQPNMFVGTSNLESAMEKLRSTFGEYGLGTATGIDLPDESTGFV
                     PKEYSFANYITNAFGQFDNYTPMQLAQYVATIANNGVRVAPRIVEGIYGNNDKGGLGN
                     LIQQLQPTEMNKVNISDSDMSILHQGFYQVAHGTSGLTTGRAFSNGALVSISGKTGTA
                     ESYVADGQQATNTNAVAYAPSDNPQIAVAVVFPHNTNLTNGVGPSIARDIINLYQKYH
                     PMN"
     gene            12295..12891
                     /gene="recR"
                     /locus_tag="VQ862_000166"
     CDS             12295..12891
                     /gene="recR"
                     /locus_tag="VQ862_000166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002896112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination protein RecR"
                     /protein_id="HET3114579.1"
                     /translation="MLYPTPIAKLIDSYSKLPGIGIKTATRLAFYTIGMSADDVNEFA
                     KNLLSAKRELTYCSICGRLTDDDPCSICTDPTRDQTTILVLEDSRDVAAMENIQEYHG
                     LYHVLHGLISPMNGISPDDINLKSLMTRLMDSEVSEVIVATNATADGEATSMYLSRLL
                     KPAGIKVTRLARGLAVGADIEYADEVTLLRAIENRTEL"
     gene            13086..14129
                     /locus_tag="VQ862_000167"
     CDS             13086..14129
                     /locus_tag="VQ862_000167"
                     /EC_number="6.3.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-alanine ligase"
                     /protein_id="HET3114580.1"
                     /translation="MKQTIILLYGGRSAEREVSVLSAESVMRAVNYDRFTVKTFFISQ
                     SGDFIKTQEFSHAPGQEDRLMTNETIDWDKKVAPSAIYEEGAVVFPVLHGPMGEDGSV
                     QGFLEVLKMPYVGCNILSSSLAMDKITTKRVLESAGIAQVPYVAIVEGDDVTAKIAEV
                     EEKLAYPVFAKPSNMGSSVGISKSENQEELRQALKLAFRYDSRVLVEQGVNAREIEVG
                     LLGNYDVKSTLPGEVVKDVAFYDYDAKYIDNKITMDIPAKISDDVVAVMRQNAETAFR
                     AIGGLGLSRCDFFYTDKGEIFLNELNTMPGFTQWSMYPLLWDNMGISYPELIERLVDL
                     AKESFDKREAHLI"
     gene            14213..15586
                     /locus_tag="VQ862_000168"
     CDS             14213..15586
                     /locus_tag="VQ862_000168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000778684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-
                     alanine ligase"
                     /protein_id="HET3114581.1"
                     /translation="MKLTIYEVAQAVGAKNDVSLFADAQLEKAEFDSRLIGTGDLFVP
                     LKGALDGHDFIETAFENGAAVTLSEKEVSNHPYILVDDVLTAFQSLASYYLEKTTVDV
                     FAVTGSNGKTTTKDMLAHLLSTRYKTYKTQGNYNNEIGLPYTVLHMPEGTEKLVLEMG
                     QDHLGDIHLLSELARPKTAIVTLVGEAHLAFFKDRSEIAKGKMQIADGMASGSLLLTP
                     ADPIVEDYLPTDKKVVRFGQGAELEITDLVERKDSLTFKANFLEQALDLPVTGKYNAT
                     NAMIASYVALQEGVSEEQIHQAFQGLELTRNRTEWKKAANGADILSDVYNANPTAMKL
                     ILETFSAIPANEGGKKIAVLADMKELGDQSIQLHNQIILSLSPDVLDTVIFYGEDIAE
                     LAQLASQMFPIGHVYYFKKTEDQDQFEDLVKQVKESLGAHDQILLKGSNSMNLAKLVE
                     SLENEDK"
     gene            15573..16184
                     /locus_tag="VQ862_000169"
     CDS             15573..16184
                     /locus_tag="VQ862_000169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HET3114582.1"
                     /translation="MKTSDFVKYLQRMIAITDTGLTFTKDPFDRERYEDLRDFLSEML
                     NQASDLDSEEVAEVLKPTSAYATPLMDVRAWIVEDEKICLVRGQGEDSWALPGGFGEV
                     GYSPTENILKEIEEETGFKAKVERLLAVFDTNRFQLQSKQYTKFVFGCKLLDGQFQEN
                     QEIADLQFFAIDQLPNLSEKRITKEQIELLWQVYQGHRGQYLD"
     gene            16275..16979
                     /locus_tag="VQ862_000170"
     CDS             16275..16979
                     /locus_tag="VQ862_000170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001055242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR02206 family membrane protein"
                     /protein_id="HET3114583.1"
                     /translation="MNLWDIFFTTQATEPPKFDLFWYVSLFTLLALTFYTAHRYREKK
                     VYQRFFQILQTVQLILLYGWYWVNHMPLSESLPFYHCRMAMFVVLLLPGQSKYKQYFA
                     LLGTFGTLAAFVYPVPDAYPFPHITILSFIFGHLALLGNSLVYLLRQYNARLLDVKGI
                     FLMTFALNALIFVVNLVTGGDYGFLTKPPLVGDHGLVANYLLVSIVLVATISLTKKIL
                     EFFLAQEAEKMIAKEA"
     gene            17198..18571
                     /gene="ftsA"
                     /locus_tag="VQ862_000171"
     CDS             17198..18571
                     /gene="ftsA"
                     /locus_tag="VQ862_000171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000090410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsA"
                     /protein_id="HET3114584.1"
                     /translation="MAREGFFTGLDIGTSSVKVLVAEQRNGELNVIGVSNAKSKGVKD
                     GIIVDIDAAATAIKSAISQAEEKAGISIKSVNVGLPGNLLQVEPTQGMIPVTSDTKEI
                     TDQDVENVVKSALTKSMTPDREVITFIPEEFIVDGFQGIRDPRGMMGVRLEMRGLLYT
                     GPRTILHNLRKTVERAGVQVENVIISPLAMVQSVLNEGEREFGATVIDMGAGQTTVAT
                     IRNQELQFTHILQEGGDYVTKDISKVLKTSRKLAEGLKLNYGEAYPPLASKETFQVEV
                     IGEVEAVEVTEAYLSEIISARIKHILEQIKQELDRRRLLDLPGGIVLIGGNAILPGMV
                     ELAQEVFGVRVKLYVPNQVGIRNPAFAHVISLSEFAGQLTEVNLLAQGAIKGENDLSH
                     QPISFGGMLQKTAQFVQSTPVQPAPAPEVEPVAPTEPMADFQQASQNKPKLADRFRGL
                     IGSMFDE"
     gene            18588..19847
                     /gene="ftsZ"
                     /locus_tag="VQ862_000172"
     CDS             18588..19847
                     /gene="ftsZ"
                     /locus_tag="VQ862_000172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000144288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsZ"
                     /protein_id="HET3114585.1"
                     /translation="MTFSFDTAAAQGAVIKVIGVGGGGGNAINRMVDEGVTGVEFIAA
                     NTDVQALSSTKAETVIQLGPKLTRGLGAGGQPEVGRKAAEESEETLTEAISGADMVFI
                     TAGMGGGSGTGAAPVIARIAKDLGALTVGVVTRPFGFEGSKRGQFAVEGINQLREHVD
                     TLLIISNNNLLEIVDKKTPLLEALSEADNVLRQGVQGITDLITNPGLINLDFADVKTV
                     MANKGNALMGIGIGSGEERVVEAARKAIYSPLLETTIDGAEDVIVNVTGGLDLTLIEA
                     EEASQIVNQAAGQGVNIWLGTSIDESMRDEIRVTVVATGVRQDRVEKVVAPQARSATN
                     YRETVKPAHSHGFDRHFDMAETVELPKQNPRRLEPTQASAFGDWDLRRESIVRTTDSV
                     VSPVERFEAPISQDEDELDTPPFFKNR"
     gene            19852..20523
                     /locus_tag="VQ862_000173"
     CDS             19852..20523
                     /locus_tag="VQ862_000173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggS family pyridoxal phosphate-dependent
                     enzyme"
                     /protein_id="HET3114586.1"
                     /translation="MNVKENTELVFREVGEASLSAHRESSSVSVIAVTKYVDVPTAEA
                     LLPLGVHHIGENRVDKFLEKYEALKDRDVTWHLIGTLQRRKVKDVIQYVDYFHALDSV
                     KLAGEIQKRSDRVIKCFLQVNISKEESKHGFSREELLEILPELARLDKIEYVGLMTMA
                     PFEASSEQLKEIFKATQDLQREIQEKQIPNMPMTELSMGMSRDYKEAIQFGSTFVRIG
                     TSFFK"
     gene            20533..21072
                     /locus_tag="VQ862_000174"
     CDS             20533..21072
                     /locus_tag="VQ862_000174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000053379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein SepF"
                     /protein_id="HET3114587.1"
                     /translation="MSLKDRFDRFIDYFTEDEDSSLPYEKRDEPVFTPVNSSQEPALP
                     MNQPSQSVGTKENNITRLHARQQELANQSQRATDKVIIDVRYPRKYEDATEIVDLLAG
                     NESILIDFQYMTEVQARRCLDYLDGACHVLAGNLKKVASTMYLLTPVNVIVNVEDIRL
                     PDEDQQGEFGFDMKRNRVR"
     gene            21072..21335
                     /locus_tag="VQ862_000175"
     CDS             21072..21335
                     /locus_tag="VQ862_000175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000576515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggT family protein"
                     /protein_id="HET3114588.1"
                     /translation="MIFLIRMIYNAVDIYSLILVAFAVMSWFPGAYESSLGRWIVALV
                     KPVLAPLQRLPLQIAGLDLSVWVAIVLVRFLGENLVRFLAMIG"
     gene            21332..22117
                     /locus_tag="VQ862_000176"
     CDS             21332..22117
                     /locus_tag="VQ862_000176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein"
                     /protein_id="HET3114589.1"
                     /translation="MNKGIYQHFSIEDRPFLDKGMEWIKKVEDSYAPFLTPFINPHQE
                     KLLKILAKTYGLACSSSGEFVSSEYVRVLLYPDYFQPEFSDFEISLQEIVYSNKFEHL
                     THAKILGTVINQLGIERKLFGDILVDEERAQIMINQQFLLLFQDGLKKIGRIPVSLEE
                     RPFTEKIDKLEQYRELNLSVSSFRLDVLLSNVLKLSRNQANQLIEKKLVQVNYHVVDK
                     SDYTVQVGDLISVRKFGRLRLFQDKGQTKKEKKKITVQLLLSK"
     gene            22126..22914
                     /gene="divIVA"
                     /locus_tag="VQ862_000177"
     CDS             22126..22914
                     /gene="divIVA"
                     /locus_tag="VQ862_000177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein DivIVA"
                     /protein_id="HET3114590.1"
                     /translation="MPITSLEIKDKTFGTRFRGFDPEEVDEFLDIVVRDYEDLVRANH
                     DKNLRIKSLEERLSYFDEIKDSLSQSVLIAQDTAERVKQAAHERSNNIIHQAEQDAQR
                     LLEEAKYKANEILRQATDNAKKVAVETEELKNKSRVFHQRLKSTIESQLAIVESSDWE
                     DILRPTATYLQTSDEAFKEVVSEVLGEPIPAPIEEEPIDMTRQFSQAEMEELQARIEV
                     ADKELSEFEAQIKQEVETPTPVVSPQVEEEPLLIQLAQCMKNQK"
     gene            23262..26054
                     /locus_tag="VQ862_000178"
     CDS             23262..26054
                     /locus_tag="VQ862_000178"
                     /EC_number="6.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000768038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoleucine--tRNA ligase"
                     /protein_id="HET3114591.1"
                     /translation="MKLKDTLNLGKTAFPMRAGLPTKEPVWQKEWEDAKLYQRRQELN
                     EGKPHFVLHDGPPYANGNIHVGHAMNHISKDIIIRSKSMSGFNAPYIPGWDTHGLPIE
                     QVLAKQGVKRKEMDLVEYLKLCREYALSQVYKQRDDFKRLGMSGDWENLYVTLTPDYE
                     AAQIRVFGEMANKGYIYRGAKPVYWSWSSESALAEAEIEYHDLVSTSLYYANKVKDGK
                     GILDTDTYIVVWTTTPFTITASRGLTVGADIDYVLVQPASETRKFVVAAELLTSLSEK
                     FGWADVQVLATYRGQELNHIVTEHPWDTAVDELVILGDHVTTDSGTGIVHTAPGFGED
                     DYNVGIANGLEVAVTVDERGIMMANAGPEFEGQFYDKVVPTVIEKLGNLLLAQEEISH
                     SYPFDWRTKKPIIWRAVPQWFASVSKFRQEILDAIDKVKFHTEWGKVRLYNMIRDRGD
                     WVISRQRAWGVPLPIFYAEDGTAIMTAETIEHVAQLFEVHGSSIWWERDAKNLLPEGF
                     THPGSPNGEFKKETDIMDVWFDSGSSWNGVLVNRPNLTYPADLYLEGSDQYRGWFNSS
                     LITSVANHGVAPYKQILSQGFTLDGKGEKMSKSLGNTIAPSDVEKQFGAEILRLWVTS
                     VDSSNDVRISMDILSQVSETYRKIRNTLRFLIANTSDFNPAQDVVAYDELRSVDKYMT
                     IRFNQLVKTIRDAYADFEFLTIYKALVNFINVDLSAFYLDFAKDVVYIEGAKSLERRQ
                     MQTVFYDILVKITKLLTPILPHTAEEIWSYLEFEAEDFVQLSELPEAQTFANQEEVLD
                     TWAAFMDFRGQAQKALEEARNAKVIGKSLEAHLTVYPNEVVKTLLEAVNSNVAQLLIV
                     SDLTIAEGPAPEAAVSFEDVAFTVERAAGQVCDRCRRIDPTTAERSYQAVICDHCASI
                     VEENFAEAVAEGFEEK"
     gene            26457..26837
                     /locus_tag="VQ862_000179"
     CDS             26457..26837
                     /locus_tag="VQ862_000179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000769852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3114592.1"
                     /translation="MKLKTLALISGIVGLVGGILLLIGPFVLLGTAVNTVATTLNGGA
                     TAGAFSGVALLLNALKIANLVLGIIAIVYYKGDNRVGAAPSVLMIVFGGVSLIPFLGW
                     VGGILVIIGGSLFLATLKKFKSEE"
     gene            27031..27321
                     /locus_tag="VQ862_000180"
     CDS             27031..27321
                     /locus_tag="VQ862_000180"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3114593.1"
                     /translation="MIESIRTYADYIDLYKNIFDDYFTKAEEGFKGTAMENNDSFTKL
                     KESTQKLFDAQKKRLNNEDRIETTKNNVIAKHCQTVLSFLVLTSFFVKNCVK"
     gene            27372..28064
                     /locus_tag="VQ862_000181"
     CDS             27372..28064
                     /locus_tag="VQ862_000181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006703946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate mutase"
                     /protein_id="HET3114594.1"
                     /translation="MVKLVFARHGESEWNKANLFTGWADVDLSEKGTQQAIDAGKLIK
                     EAGIKFDQAYTSVLKRAIKTTNLALEASDQLWVPVEKSWRLNERHYGGLTGKNKAEAA
                     EQFGDEQVHIWRRSYDVLPPNMDRDDEHSAHTDRRYASLDDSVIPDAENLKVTLERAL
                     PFWEDKIAPALKDGKNVFVGAHGNSIRALVKHIKGLSDDEIMDVEIPNFPPLVFEFDE
                     KLNVVSEYYLGK"
     gene            28117..30528
                     /locus_tag="VQ862_000182"
     CDS             28117..30528
                     /locus_tag="VQ862_000182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000620712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 95 protein"
                     /protein_id="HET3114595.1"
                     /translation="MIRNKKQDYVLAYKQPVSTTYMGWEEEALPIGNGSLGAKVFGLI
                     GAERIQFNEKSLWSGGPLPDSSDYQGGNLQDQYVFLAEIRQALEKRDYNLAKELAEQH
                     LIGPKTSQYGTYLSFGDIHIEFSQQGTTLSQVTDYQRQLNISKALVTTSYVYKGTRFE
                     REAFASFPDDLLVQRFTKEGAETLDFTIELSLTCDLASDGKYEQEKSDYKECKLDITD
                     SHILMKGRVKDNDLRFASYLAWETDGDIRVWSDRVQISGASYANLFLAAKTDFAQNPA
                     SNYRKKLDLEQQVIDLVDTAKEKGYTQLKSRHIEDYQALFQRVQLDLEANVDAFTTDD
                     LLKNYKPQEGQALEELFFQYGRYLLISSSRDCPDALPANLQGVWNAVDNPPWNSDYHL
                     NVNLQMNYWPAYVTNLLEAVFPVINYVDDLRVYGRLAAVKYAGIVSQKGEENGWLVHT
                     QATPFGWTAPGWDYYWGWSPAANAWMMQTVYEAYSFYRDQDYLREKIYPMLRETVRFW
                     NAFLHKDQQAQRWVSSPSYSPEHGPISIGNTYDQSLIWQLFHDFIQAAQELGLDEDLL
                     TEVKEKSDLLNPLQITQSGRIREWYEEEEQYFQNEKVEAQHRHASHLVGLYPGNLFSY
                     KGQEYIEAARASLNDRGDGGTGWSKANKINLWARLGDGNRAHKLLAEQLKTSTLPNLW
                     CSHPPFQIDGNFGATSGMAEMLLQSHAAYLVPLAALPDAWSTGSVSGLMARGHFEVSM
                     SWEDKKLLQLTILSRSGGDLRVSYPDIEKSVIKMNQEKIKAKCMGKDCISVATAEGDL
                     VQFYF"
     gene            30778..31479
                     /locus_tag="VQ862_000183"
     CDS             30778..31479
                     /locus_tag="VQ862_000183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3114596.1"
                     /translation="MAYIEMKHCYKRYQVGDTEIVANRDVNFEIEKGELVIILGASGA
                     GKSTVLNLLGGMDTNDEGEIWIDGVNIADYSSHQRTNYRRNDVGFVFQFYNLVSNLTA
                     KENVELASEIVTDALNPDQVLTDVGLAHRLNNFPAQLSGGEQQRVSIARAVAKNPKIL
                     LCDEPTGALDYQTGKQVLKILQDMSRQKGATVIIVTHNGALAPIADRVIHMHDASVKD
                     VVLNQHPQDIDSLEY"
     gene            31481..34189
                     /locus_tag="VQ862_000184"
     CDS             31481..34189
                     /locus_tag="VQ862_000184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000595876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HET3114597.1"
                     /translation="MIKRKTYWKDLIQSFTDSKGRFLSILILMMLGSLALVGLKVTSP
                     NMEATANAYLTTAQTLDLAVMSNYGLDQADQEELKQTEGAEVEFGYLTDVTMDNGQDA
                     IRLYSKPERISTFQLRKGRLPQSDREIALATHLQGQYSVGQEISFKEKEEGHSSLKDH
                     TYTITGFVDSAEILSQRDMGYAGSGSGTLTAYGVILPSQFDQKVYNIARLKYQDLAGL
                     NAFSSAYEEKSKQHQEDLEQTLSDNGKVRLQLLKKEGQESLDKGQETLDKAQTNLQEG
                     KRRLAAAQARIQAQESQLALFPQAQREQASAQLTQAKQELGKEEDKLKQAEQNLAQEK
                     EKLEKHQQVLDDLAEPRYQVYNRQTMPGGQGYLMYSNASSSIRAVGNIFPVVLYAVAA
                     MVTFTTMTRFVDEERTHAGIFKALGYRSKDIIAKFLLYGLVAGTVGTALGSILGHYLL
                     ASVISSVITKGMVVGETQIQFYWTYSLLALVLSWLASVLPAYLVAWRELHDEAAQLLL
                     PKPPVKGAKILLERIGFIWRRLSFTHKVTARNIFRYKQRMLMTIFGVAGSVALLFAGL
                     GIQSSVAGVPSKQFQQIQQYQMLVSENPSATNQDKVELAEVLKGQEILAYQKIYSKTL
                     DKDFKGRAGLQNITLMMIEKEDLTPFIHLQHHQQELTLKDGIVITAKLAQLAGVKVGQ
                     TLEIEGKELKVAAITENYVGHFIYMSQASYEQLYGQLPQANTYLVSLRDTSATSIESQ
                     AGLLMNQSAVSSVVQNASAIRLFDSIASSLNQTMTILVIVSVLLAIVILYNLTNINVA
                     ERIRELSTIKVLGFHNNEVTLYIYRETIVLSLVGIVLGLVAGFYLHQFLIQMISPATI
                     LFYPQVGWEVYVIPVAAVSIILTLLGFFVNYYLRKVDMLEALKSVE"
     gene            complement(34285..34776)
                     /gene="tpx"
                     /locus_tag="VQ862_000185"
     CDS             complement(34285..34776)
                     /gene="tpx"
                     /locus_tag="VQ862_000185"
                     /EC_number="1.11.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004245092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol peroxidase"
                     /protein_id="HET3114598.1"
                     /translation="MVTFLGNPVSFTGKQLQVGDKALDFSLTTTDLSKKSLADFDGKK
                     KVLSVVPSIDTGICSTQTRRFNEELAGLDNTVVLTVSMDLPFAQKRWCGAEGLDNAIM
                     LSDYFDHSFGRDYALLINEWHLLARAVFVLDTDNTIRYVEYVDNINSEPNFEAAIAAA
                     KAL"
     gene            complement(34899..35828)
                     /gene="psaA"
                     /locus_tag="VQ862_000186"
     CDS             complement(34899..35828)
                     /gene="psaA"
                     /locus_tag="VQ862_000186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000733059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding
                     lipoprotein/adhesin PsaA"
                     /protein_id="HET3114599.1"
                     /translation="MKKLGTLLVLFLSAIILVACASGKKDTTSGQKLKVVATNSIIAD
                     ITKNIAGDKIDLHSIVPIGQDPHEYEPLPEDVKKTSEADLIFYNGINLETGGNAWFTK
                     LVENAKKTENKDYFAVSDGVDVIYLEGQNEKGKEDPHAWLNLENGIIFAKNIAKQLSA
                     KDPNNKEFYEKNLKEYTDKLDKLDKESKDKFNKIPAEKKLIVTSEGAFKYFSKAYGVP
                     SAYIWEINTEEEGTPEQIKTLVEKLRQTKVPSLFVESSVDDRPMKTVSQDTNIPIYAQ
                     IFTDSIAEQGKEGDSYYSMMKYNLDKIAEGLAK"
     gene            complement(35860..36708)
                     /locus_tag="VQ862_000187"
     CDS             complement(35860..36708)
                     /locus_tag="VQ862_000187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000559784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HET3114600.1"
                     /translation="MIAEFIDGLQKFHFLQNALITAIVVGIVAGAVGCFIILRGMSLM
                     GDAISHAVLPGVALSFILGLDFFIGAIVFGLLAAIIITYIKGNSIIKSDTAIGITFSS
                     FLALGIILIGVAKSSTDLFHILFGNILAVQDTDMFITMGVGAAILLLIWIFFKQLLIT
                     SFDELLAKAMGMPVNFYHYLLMVLLTLVSVTAMQSVGTILIVAMLITPAATAYLYANS
                     LKSMIFLSSTFGATASVLGLFIGYSFNVAAGSSIVLTAASFFLISFFIAPKQRYLKLK
                     NKHLLK"
     gene            complement(36705..37427)
                     /locus_tag="VQ862_000188"
     CDS             complement(36705..37427)
                     /locus_tag="VQ862_000188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HET3114601.1"
                     /translation="MIRIENLSVSYKETLALKDISLVLHGPTITGIIGPNGAGKSTLL
                     KGMLGIIPHQGQAFLDDKEVKKSLHRIAYVEQKINIDYNFPIKVKECVSLGLFPSIPL
                     FRSLKAKHWKKVQEALEIVGLADYAERQISQLSGGQFQRVLIARCLVQEADYILLDEP
                     FAGIDSVSEEIIMNTLRDLKKAGKTVLIVHHDLSKIPHYFDQVLLVNREVIAFGPTKE
                     TFTETNLKEAYGNQLFFNGGDL"
     gene            37718..39610
                     /gene="pepO"
                     /locus_tag="VQ862_000189"
     CDS             37718..39610
                     /gene="pepO"
                     /locus_tag="VQ862_000189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endopeptidase PepO"
                     /protein_id="HET3114602.1"
                     /translation="MTRYQDDFYDAINGEWQQTAEIPADKSQTGGFVDLDQEIEDLML
                     ATTDKWLAGEEVPEDAILENFVKYHRLVRDFDKREADGITPVLPLLKEFQELETFADF
                     TAKLAEFELAGKPNFLPFGVSPDFMDARINVLWASAPSTILPDTTYYAEEHPQREELL
                     TLWKESSANLLKAYDFSDEEIEDLLEKRLELDRRVAAVVLSNEESSEYAKLYHPYSYE
                     DFKKFAPALPLDDFFKAVIGQLPDKVIVDEERFWQAAEQFYSEEAWSLLKATLILSVV
                     NLSTSYLTEDIRVLSGAYSRALSGVPEAKDKVKAAYHLAQEPFKQALGLWYAREKFSP
                     EAKADVEKKVATMIDVYKERLLKNDWLTPETCKQAIVKLNVIKPYIGYPEELPARYKD
                     KVVNETASLFENALAFARVEIKHSWSKWNQPVDYKEWGMPAHMVNAYYNPQKNLIVFP
                     AAILQAPFYDLHQSSSANYGGIGAVIAHEISHAFDTNGASFDENGSLKDWWTESDYAA
                     FKEKTQKVIDQFDGQDSYGATINGKLTVSENVADLGGIAAALEAAKREADFSAEEFFY
                     NFGRIWRMKGRPEFMKLLASVDVHAPAKLRVNVQVPNFDDFFTTYDVKEGDGMWRSPE
                     ERVIIW"
     gene            complement(39733..40362)
                     /locus_tag="VQ862_000190"
     CDS             complement(39733..40362)
                     /locus_tag="VQ862_000190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000690864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HET3114603.1"
                     /translation="MKIHKTVNPVAYENTYYLEGEKHLIVVDPGSHWEAIRQTIEKIN
                     KPICAILLTHAHYDHIMSLDLVRETFGNPPVYIAESEASWLYTPVDNLSGLPRHDDMA
                     DVVTKPAEHTFVFHEEYQLEEFRFKVLPTPGHSIGGVSLVFPDAHLVLTGDALFRETI
                     GRTDLPTGSMEQLLHSIQTQLFTLPNYDVYPGHGPATTIAHEKAFNPFF"
     gene            41358..43580
                     /locus_tag="VQ862_000191"
     CDS             41358..43580
                     /locus_tag="VQ862_000191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019316080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional (p)ppGpp
                     synthetase/guanosine-3',5'-bis(diphosphate)
                     3'-pyrophosphohydrolase"
                     /protein_id="HET3114604.1"
                     /translation="MPKEVNLTGEEVVALTKEYLTEEDVHFVHKALVYAVECHSGQYR
                     KSGEPYIIHPIQVAGILAKLKLDAVTVACGFLHDVVEDTDATLDDLEREFGPDVRMIV
                     DGVTKLGKVEYKSIEEQLAENHRKMLMAMSEDIRVILVKLSDRLHNMRTLKHLRKDKQ
                     ERISKETMEIYAPLAHRLGISSVKWELEDLSFRYLNPTEFYKITHMMKEKRREREALV
                     DEVVTKLEEYTTERHLKGKIYGRPKHIYSIFRKMQDKRKRFEEIYDLIAIRCILDTQS
                     DVYAMLGYVHEFWKPMPGRFKDYIANRKANGYQSIHTTVYGPKGPIEFQIRTKEMHEV
                     AEYGVAAHWAYKKGIKGQVNSKESAIGMNWIKEMMELQDQADDAKEFVDSVKENYLAE
                     EIYVFTPDGAVRSLPKDSGPIDFAYEIHTKVGEKATGAKVNGRMVPLTTKLKTGDQVE
                     IIANPNSFGPSRDWLNMVKTSKARNKIRQFFKNQDKELSVNKGREMLMAQFQENGYVA
                     NKFMDKRHMDQVLQKTSYKTEDSLFAAIGFGEIGAITVFNRLTEKERREEERAKAKAE
                     AEELVKGGEVKVENKETLKVKHEGGVVIEGASGLLVRIAKCCNPVPGDDIVGYITKGR
                     GVAIHRVDCMNLRAQENYEQRLLDVEWEDQYSSSNKEYMAHIDIYGLNRTGLLNDVLQ
                     VLSNTTKNISTVNAQPTKDMKFANIHVSFGIANLSTLTTVVDKIKSVPEVYSVKRTNG
                     "
     gene            43610..44053
                     /locus_tag="VQ862_000192"
     CDS             43610..44053
                     /locus_tag="VQ862_000192"
                     /EC_number="3.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-tyrosyl-tRNA(Tyr) deacylase"
                     /protein_id="HET3114605.1"
                     /translation="MKIIIQRVKKAQVSIEGQIQGKINQGFLLLVGVGPEDQEEDLDY
                     AVRKLVNMRIFSDAEGKMNLSVKDIEGEILSISQFTLFADTKKGNRPAFTGAAKPDMA
                     SDFYDAFNQKLAQEVPVQTGIFGADMQVELVNNGPVTIILDTKKR"
     gene            complement(44320..44505)
                     /locus_tag="VQ862_000193"
     CDS             complement(44320..44505)
                     /locus_tag="VQ862_000193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000720032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3114606.1"
                     /translation="MKKIIFIKTIQLLVIDGIMLAFLTFKRELTWDWILIYSGWLIFF
                     HPVLLTYLSNQLCDHFS"
     gene            complement(44524..44937)
                     /locus_tag="VQ862_000194"
     CDS             complement(44524..44937)
                     /locus_tag="VQ862_000194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000737919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3114607.1"
                     /translation="MKKLYRIHFIAIAVIDLLLFAFFITRLETSFEWLLLSGLIFFLD
                     QGLLLFLLVVRLKHQFAEIYPQINKKIRFYYLGILTIDFLFFVLLAFISSQRFSSLMP
                     IITARHSTFYYMTADYLGENYPDFYDKHISLWECL"
     gene            complement(45068..45715)
                     /locus_tag="VQ862_000195"
     CDS             complement(45068..45715)
                     /locus_tag="VQ862_000195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001819460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide mononucleotide transporter"
                     /protein_id="HET3114608.1"
                     /translation="MVVGIAIASGYLNSRLHKFVDWGLWTALVPFGLISVTNVGISML
                     STRFTGKLSKWGNYFGIVNTILSGAIDYILGNKAAIITYPVTFLIYTFAIKKWKASQE
                     GRPNQMSQKQVKLAPIIISIIAFLFAFVTNYIGYGGKMNLLAYVTTIAFALSLIANAL
                     NALKLTTQWGFWLIYNFVQLTKAGIQGNFANIGKYIFYILNAIGALFVWNDEEVR"
     gene            complement(45741..45932)
                     /locus_tag="VQ862_000196"
     CDS             complement(45741..45932)
                     /locus_tag="VQ862_000196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3114609.1"
                     /translation="MSRKSTNFSSPLPTLKVLFSGFYFYHFILLSFGVRIFEKNGRIF
                     EKKKGSLTYEKITKNFCYI"
     gene            complement(45913..46563)
                     /locus_tag="VQ862_000197"
     CDS             complement(45913..46563)
                     /locus_tag="VQ862_000197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000188500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent transcriptional regulator"
                     /protein_id="HET3114610.1"
                     /translation="MTPNKEDYLKCIYEIGIDLHKITNKEIAARMQVSPPAVTEMIKR
                     MKSENLILKDKECGYLLTDLGLKLVSELYRKHRLIEVFLVHHLDYTSDQIHEEAEVLE
                     HTVSDLFVERLDKLLGFPKTCPHGGTIPAKGELLVEINNLPLADIKEAGAYRLTRVHD
                     SFDILHYLDKHSLHIGDQLQVKQFDGFSNTFTILSNDEDLQVNMDIAKQLYVEKIN"
     gene            46675..47517
                     /locus_tag="VQ862_000198"
     CDS             46675..47517
                     /locus_tag="VQ862_000198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase family protein"
                     /protein_id="HET3114611.1"
                     /translation="MTKIALLSDIHGNTTALEAVLADARQIGVDEYWLLGDILMPGTG
                     RRRILDLLDQLPITARVLGNWEDSLWHGVRKELDSTRPSQRYLLRQCQYVLEEISLEE
                     IEVLHNQPLQIHRQFGDLTVGISHHLPDKNWGRELIHTGKQEDFDRLVTHPPCDIAVY
                     GHIHQQLLRYGTGGQLIVNPGSIGQPFFLDAQLRKDLRAQYMILEFDDKGLVDMDFRR
                     VDYDVAAELQLAKDLRLPYFEVYYESLVNGIHHTHHQEFLRELAQKEGCDRELDDWLK
                     SGND"
     gene            47593..48030
                     /locus_tag="VQ862_000199"
     CDS             47593..48030
                     /locus_tag="VQ862_000199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004263219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rrf2 family transcriptional regulator"
                     /protein_id="HET3114612.1"
                     /translation="MQIPSRFTIATHMLIIIALEGKESKVTSDFLAASVGVNPVIIRK
                     ILSQLKKAELISVARGTGGTEIVKDLKDISLLDVYQAVECLGKTGQLFSFHDNPNPNC
                     PVGAHIHDVLDQKLERIQLTMEAELGQTSLEKVVADAESQMKD"
     gene            48098..48400
                     /locus_tag="VQ862_000200"
     CDS             48098..48400
                     /locus_tag="VQ862_000200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000281600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3114613.1"
                     /translation="MYLVIGIVLAFIVSFWKDNRSLWNPVLFLLSLISSYFYLSYLFY
                     KNGYENVQLAFYVFAFVLLPFLLFLSGIFLIYNGVILLKREGRSKPHYLSMLFDFY"
     gene            complement(48491..49564)
                     /locus_tag="VQ862_000201"
     CDS             complement(48491..49564)
                     /locus_tag="VQ862_000201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001273827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2974 domain-containing protein"
                     /protein_id="HET3114614.1"
                     /translation="MANIFDYLKDVAYDSYYDLPLNELDILTLIEITYLSFDNLVSTL
                     PQRLLDLAPQVPRDPTMLTSKNRLQLLDELAQHKRFKNCKLSHFINDIDPELQKQFAA
                     MTYRVSLDTYLIVFRGTDDSIIGWKEDFHLTYMKEIPAQKHALRYLKNFFAHHPKQKV
                     ILAGHSKGGNLAIYAASQIEQSLQNQITAVYTFDAPGLHQELTQTAGYQRIMDRSKIF
                     IPQGSIIGMMLEIPAHQIIVQSTALGGIAQHDTFSWQIEDKHFVQLDKTNSDSQQVDT
                     TFKEWVATVPDEELQLYFDLFFGTILEAGISSINDLASLKALEYIHHLFVQAQSLTPE
                     ERETLGRLTQLLIDTRYQAWKNR"
     gene            49720..50397
                     /locus_tag="VQ862_000202"
     CDS             49720..50397
                     /locus_tag="VQ862_000202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000548969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET3114615.1"
                     /translation="MHKILLVEDDQVIRQQVGKMLSEWGFEVVLVEDFMEVLSLFVQS
                     EPHLVLMDIGLPLFNGYHWCQEIRKISKVPIMFLSSRDQAMDIVMAINMGADDFVTKP
                     FDQQVLLAKVQGLLRRSYEFGRDESLLEYAGVILNTKSMDLHYQGQVLNLTKNEFQIL
                     RVLFEHAGNIVARDDLMRELWNSDFFIDDNTLSVNVARLRKKLEEQGLVGFIETKKGI
                     GYGLKHA"
     gene            50390..51364
                     /locus_tag="VQ862_000203"
     CDS             50390..51364
                     /locus_tag="VQ862_000203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HET3114616.1"
                     /translation="MLDWKQFFLAYLRSRSRLFIYLLSLAFLVLLFQFLFASLGIYFL
                     YFFFLCCFVTILFFTWDILVETQVYRQELLYGEREAKSPLEIALAEKLEAREMELYQQ
                     RSKAERKLTDLLDYYTLWVHQIKTPIAASQLLVAEVVDRQLKQQLEQEIFKIDSYTNL
                     VLQYLRLESFHDDLVLKQVQIEDLVKEIIRKYALVFIQKGLNVNLHDLDKEIVTDKKW
                     LLVVIEQIISNSLKYTKEGGLEIYMDDQELCIKDTGIGIKNSDVLRVFERGFSGYNGR
                     LTQQSSGLGLYLSKKISEELGHQIRIESEVGKGTTVRIQFAQVNLVLE"
     gene            complement(51413..53356)
                     /gene="thrS"
                     /locus_tag="VQ862_000204"
     CDS             complement(51413..53356)
                     /gene="thrS"
                     /locus_tag="VQ862_000204"
                     /EC_number="6.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000608363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine--tRNA ligase"
                     /protein_id="HET3114617.1"
                     /translation="MINITFPDGAVREFESGVTTFEIAQSISNSLAKKALAGKFNGKL
                     IDTTRAITEDGSIEIVTPDHEDALPILRHSAAHLFAQAARRLFPDIHLGVGPAIEDGF
                     YYDTDNTAGQISNEDLPRIEEEMQKIVKENFPSIREEVTKDEAREIFKNDPYKLELIE
                     EHSEDEGGLTIYRQGEYVDLCRGPHVPSTGRIQIFHLLHVAGAYWRGNSDNAMMQRIY
                     GTAWFDKKDLKNYLQMREEAKERDHRKLGKELDLFIISQEVGQGLPFWLPNGATIRRE
                     LERYIVNKELASGYQHVYTPPLASVELYKTSGHWDHYQEDMFPTMDMGDGEEFVLRPM
                     NCPHHIQVFKHHVHSYRELPIRIAEIGMMHRYEKSGALTGLQRVREMSLNDGHLFVTP
                     EQIQEEFQRALQLIIDVYEDFNLTDYRFRLSLRDPQDTHKYFDNDEMWENAQTMLRAA
                     LDEMGVNYFEAEGEAAFYGPKLDIQIKTALGKEETLSTIQLDFLLPERFDLKYIGADG
                     EDHRPVMIHRGVISTMERFTAILIENYKGAFPTWLAPHQVTLIPVSNEKHVDYAWEVA
                     KKLRDRGVRADVDERNEKMQFKIRASQTSKIPYQLIVGDKEMEDETVNVRRYGQKETQ
                     TVSVDNFVQAILADIANKSRVEK"
     gene            complement(53414..53737)
                     /locus_tag="VQ862_000205"
     CDS             complement(53414..53737)
                     /locus_tag="VQ862_000205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000422771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MazG-like protein"
                     /protein_id="HET3114618.1"
                     /translation="MELQELVERSWAIRQAYHELEVKHHDSKWTVEEDLLALSNDIGN
                     FQRLVMTKQGRYYDETPYTLEQKLSENIWWLLELSQRLDIDILTEMENFLSDKEKQLN
                     VRTWK"
     gene            54596..55225
                     /locus_tag="VQ862_000206"
     CDS             54596..55225
                     /locus_tag="VQ862_000206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="HET3114619.1"
                     /translation="MKLAVIAANGQAGKAIVEEAVKRGHEVTAIVRSENKSQAESIIK
                     KDLFELTKDDLTGFDAVISAFGAYTPDTLPLHSKSIELFNQLLAGTQTRFLVVGGSGS
                     FYIDETKTTRLLDTSDFPEEFKPLAKAQADELDLLRTKNNLNWTFVSPAVDFIPDGEK
                     TGNYILAGEIFTTNEKGISQISYADYAIGLVDELEKGHHIKERISLLEK"
     gene            55366..55635
                     /gene="rpsO"
                     /locus_tag="VQ862_000207"
     CDS             55366..55635
                     /gene="rpsO"
                     /locus_tag="VQ862_000207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S15"
                     /protein_id="HET3114620.1"
                     /translation="MAISKEKKNEIIAQYARHEGDTGSVEVQVAVLTWEINHLNEHIK
                     QHKKDHATYRGLMKKIGRRRNLLAYLRKNDVNRYRELINSLGLRR"
     gene            56451..57065
                     /locus_tag="VQ862_000208"
     CDS             56451..57065
                     /locus_tag="VQ862_000208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000531723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CadD family cadmium resistance transporter"
                     /protein_id="HET3114621.1"
                     /translation="MGQTIISAIGVYISTSIDYLIILIILFAQLSQNKQKWHIYAGQY
                     LGTGLLVGASLVAAYVVNFVPEEWMVGLLGLIPIYLGIRFAILGEDAEEEEEEIIERL
                     EQSKANQLFWTVTLLTIASGGDNLGIYIPYFASLDWSQTLVALLVFVIGIIIFCEISR
                     VLSSIPLIFETIEKYERIIVPLVFILLGLYIMYENGTIETFLIV"
     gene            complement(57358..58107)
                     /locus_tag="VQ862_000209"
     CDS             complement(57358..58107)
                     /locus_tag="VQ862_000209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000500208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-acyl-sn-glycerol-3-phosphate acyltransferase"
                     /protein_id="HET3114622.1"
                     /translation="MFYTYLRGLVVLLLWSINGNAHYHNTDKIPNQDENYILVAPHRT
                     WWDPVYMAFATKPKQFIFMAKKELFTNRIFGWWIRMCGAFPIDRENPSASAIKYPINV
                     LKKSDRSLIMFPSGSRHSNDVKGGAALIAKMAKVRIMPVTYTGPMTLKGLISRERVDM
                     NFGNPIDISDIKKMNDEGIETVANRIQTEFQRLDEETKQWHNDKKPNPLWWFIRIPAL
                     ILAIILAILTIIFSFIASFIWNPDKKREELA"
     gene            58240..60576
                     /locus_tag="VQ862_000210"
     CDS             58240..60576
                     /locus_tag="VQ862_000210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000360031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IC family P-type ATPase"
                     /protein_id="HET3114623.1"
                     /translation="MDKNKIMGLTQREVKERQAEGLVNDFTASASTSTWQIVKRNVFT
                     LFNALNFAIALALAFVQAWSNLVFFAVICFNAFSGIVTELRAKHMVDKLNLMTKEKVK
                     TIRDGQEVALNPEELVLGDVIRLSAGEQIPSDALVLEGFAEVNEAMLTGESDLVQKEV
                     DGLLLSGSFLASGSVLSQVHHVGADNYAAKLMLEAKTVKPINSRIMKSLDKLAGFTGK
                     IIIPFGLALLLEALLLKGLPLKSSVVNSSTALLGMLPKGIALLTITSLLTAVIKLGLK
                     KVLVQEMYSVETLARVDMLCLDKTGTITQGKMQVEAVLPLTETYGEEAIASILTSYMA
                     HSEDKNPTAQAIRQRFVGDVAYPMISNLPFSSDRKWGAMELEGLGTVFLGAPEMLLDS
                     EVPEAREALERGSRVLVLALSQEKLDHHKPQKPSDIQALALLEILDPIREGAAETLNY
                     LRSQEVGLKIISGDNPVTVSSIAQKAGFADYHSYVDCSKITDEELIALAEETAIFGRV
                     SPHQKKLIIQTLKKAGHTTAMTGDGVNDILALREADCSIVMAEGDPATRQIANLVLLN
                     SDFNDVPEILFEGRRVVNNIAHIAPIFLIKTIYSFLLAVICIASALLGRSEWILIFPF
                     IPIQITMIDQFVEGFPPFVLTFERNIKPVEPNFLRKSMLRALPSALMVVFSVLFVKIF
                     GTSQGWSELEISTLLYYLLGSIGFLSVFRACMPFTLWRVLLIVWSVGGFLATALFPRI
                     QKLLEISTLTEQTLPVYGVMMLVFTVIFILTSRYQARK"
     gene            61105..62568
                     /locus_tag="VQ862_000211"
     CDS             61105..62568
                     /locus_tag="VQ862_000211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000087917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HET3114624.1"
                     /translation="MSRKQEQMETLLLLLRDSKDYISAKVLGEKLNCSDKTVYRLVKV
                     INKDCPVEAFILSEKGRGFKLNPRSSLVDVDGNFTEAFDPEVRREKLLERLLLTAPKP
                     HSIYDLGEEFYVSESVVLKDRQILQESLAIYGLDLKMRQRKLFIDGDEAQIRSAILNL
                     LPMFNQLDLEQITQNKVQPLDGELAHFCLGLLITLERELGVNIPYPYNINIFSHLYIF
                     ISRNRRSTSIHVVAPSKPTIVDEKIYSVCQKIIQEIEQYFKMKVDAVEIDYLYQYVVS
                     SRLQKPFSSGKLPFSQRVLDVTHYYFSRMCMDNREIETTDPDFVDLASHISPLLRRLD
                     NRVQIKNSLLSQILLTYPNLVKELTTISKEVSLVFGFASLSLDEIGFLVLYFARFQEK
                     RARPLKTVVMCTSGVGTSELLRARLEKQFTELDIIDVVAYHQLDELINLYPDLDFIVT
                     TVALQEPASVPFVLVSVFLTEGDKQRLQAKIQEINYE"
     gene            62561..62989
                     /locus_tag="VQ862_000212"
     CDS             62561..62989
                     /locus_tag="VQ862_000212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001061750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HET3114625.1"
                     /translation="MNNLSLVLMDISVQNRQEAYKELANQISLLVSEDTEKIEELLYY
                     RERQGSIEVAKGVLLPHCEGNFQHHVLVITRLKSPIREWSKDIQCVDLIIGLAIAVSQ
                     DKSCIKTLMRRLADESFINQLKQLTKEELREIIYGNQRYS"
     gene            62967..63416
                     /locus_tag="VQ862_000213"
     CDS             62967..63416
                     /locus_tag="VQ862_000213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000402985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HET3114626.1"
                     /translation="MEIKDILNVSLIQTDLQMQSKEEVFEALAQLLVETGYVSDRDQF
                     IEGLYQREAEGQTGIGNYIAIPHSKSSAVEKAGVVIAINHNEIPWETIDGKGVKVIVL
                     FAVGDDTEAAREHLKTLSLFARKLGNDEVVAKLVRAQTSDDVIAAFC"
     gene            63444..63755
                     /locus_tag="VQ862_000214"
     CDS             63444..63755
                     /locus_tag="VQ862_000214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000706299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIB"
                     /protein_id="HET3114627.1"
                     /translation="MKIVGVAACTVGIAHTYIAQEKLENAAKVAGHVIHVETQGTIGV
                     ENELSQEQIDAADVVILAVDVKISGMERFEGKKIIKVPTEVAVKSPNKLIAKAVEIVT
                     K"
     gene            63781..64866
                     /locus_tag="VQ862_000215"
     CDS             63781..64866
                     /locus_tag="VQ862_000215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000912151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIC"
                     /protein_id="HET3114628.1"
                     /translation="MLKHLNLKGHLLTAISYMIPIVCGAGFLVAIGLAMGGGVPDALV
                     AGKFTIWDALATMGGKALGLLPVVIATGLSYSIAGKPGIAPGFVVGLIANSVGSGFIG
                     GILGGYIAGFLVQAIIKKVKVPNWIKGLMPTLIIPFVASLVSSLIMIYIIGAPIAAFT
                     NWLTSLLQSLGSASNGLMGAVIGVLSAVDFGGPLNKTVYAFVLTLQAEGVKEPLTALQ
                     LVNTATPVGFGLAYFIAKLLKKNIYTQEEIETLKSAVPMGIVNIVEGVIPIVMNNLVP
                     GLIATGIGGAVGGAVSLTMGADSAVPFGGVLMLPTMTRPVAGICALLANIVVTGLVYA
                     ILKKPIKHTEPVMTVEEEIDLSDIEIL"
     gene            64877..65572
                     /locus_tag="VQ862_000216"
     CDS             64877..65572
                     /locus_tag="VQ862_000216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000086495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HET3114629.1"
                     /translation="MSRIEFSPSLMTMDLDKFKEQITFLNDKVASYHIDIMDGHFVPN
                     ITLSPWFIQEVQKISDTPLSVHLMVTDPTFWVDQVLDLQCEYICIHAEVLNGLAFRLI
                     DKIHDAGLKAGVVLNPETPVSTIFPYIDLLDKVTIMTVDPGFAGQRFLKSTLYKIQEL
                     RQLRVQNGYHYIIEMDGSSSRKTFKQIDVAGPDIYVIGRSGLFGLDDDIAKAWDICSR
                     DYEEMTGKTMPIK"
     gene            65609..67579
                     /gene="tkt"
                     /locus_tag="VQ862_000217"
     CDS             65609..67579
                     /gene="tkt"
                     /locus_tag="VQ862_000217"
                     /EC_number="2.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000058259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HET3114630.1"
                     /translation="MSLQSVNAIRFLGVDAINKSNSGHPGIVMGAAPMAYSLFTKHLR
                     ITPEQPNWINRDRFILSAGHGSMLLYALLHLTGYKDVSMDEIKNFRQWGSKTPGHPEV
                     THTSGVDATSGPLGQGISTAVGFAQAERFLAAKYNKDGFPIFDHYTYVIAGDGDFMEG
                     VSAEAASYAGHQALDKLIVLYDSNDICLDGETKDTFSENVRARYDAYGWHTVLVEDGT
                     DLAAISTAIETAKFSGKPSLIEVKTVIGYGSPNKSGTNAVHGAPLGAEETGATRKFLG
                     WDYDPFEVPEEVYSDFKTNVADRGQEAYDAWASLVSDYKVAYPEVASEIDAIVAGKSP
                     VTITEKDFPVYENGFSQATRNSSQDAINTAAAVLPTFLGGSADLAHSNMTYIKADGLQ
                     DKYNPLNRNIQFGVREFAMGTILNGMALHGGLRVYGGTFFVFSDYVKAAIRLSAIQEL
                     PVTYVFTHDSIAVGEDGPTHEPVEHLAGLRSMPNLTVIRPADARETQAAWHHALTSTT
                     TPTVIVLTRQNLVVEEGTDFGKVAKGAYVVYDTPGFDTIIIATGSEVNLAIKAAKELV
                     LQGGKVRVVSMPSTELFDAQDATYKEDILPSKTRRRVAIEMAATQSWYKYVGLDGAVI
                     GIDIFGASAPAQTVIDNYGFTVENIVAQVKSL"
     gene            67952..>68162
                     /locus_tag="VQ862_000218"
     CDS             67952..>68162
                     /locus_tag="VQ862_000218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HET3114631.1"
                     /translation="MKLSYEDKVQIYELRKQGQSFKQLSKRFGVDVSGLKYMVKLIDR
                     YGIEFVKKGKNRYYSPDLKQEMINKV"
BASE COUNT        20172 a        12459 c        15296 g        20235 t
ORIGIN      
        1 atacaccaga acaagccaaa caaatccttg aatatggagt gcgaggcatc gttgttggtg
       61 gcgccattac tagaccaaaa gagattacag aacgcttcgt tgctagtctt aaataagatg
      121 tgagagggag ttttatgttt aaagttttac aaaaagttgg aaaagctttt atgttaccta
      181 tagctatact tcctgcagca ggtctacttt tggggattgg tggtgcactt tcaaacccaa
      241 ccacgatagc aacttatcca atactagaca atagtatttt tcaatcaata ttccaagtaa
      301 tgagctctgc aggagaggtt gtattcagta atttgtcact acttctctgt gtgggattat
      361 gtattggctt agcgaaacga gataaaggaa ccgctgcgtt agcaggagta actggttact
      421 tagttatgac tgcaacgatc aaagctttgg taaaactttt tatggcagaa ggatctgcaa
      481 ttgatactgg agttattgga gcattagttg tcggaatagt tgccgtatat ttgcacaacc
      541 gatataacaa tattcaatta ccttccgctt taggattctt tggaggttca cgcttcgttc
      601 ctattgttac atcgttctct tctatcttga ttggctttgt cttctttgtt atttggccac
      661 ctttccaaca acttcttgtt tctacaggtg gatatatttc tcaggcgggt ccaattggaa
      721 cttttctata tggattttta atgagacttt ctggagcagt aggcttacat catataattt
      781 accctatgtt ttggtatact gaacttggtg gtgttgagac tgttgcagga caaacagtgg
      841 ttggagctca aaaaatattt tttgctcaat tagccgatcc ggcccattct ggattattta
      901 cagaaggaac aaggtttttt gcaggtcgtt tctcaacaat gatgttcggt ttaccggctg
      961 cctgtttagc gatgtaccat agtgttccta aaaatcgtcg taaaaaatac gcgggtttgt
     1021 tttttggagt tgctttaaca tcttttatta ccggtattac agaaccaatt gaatttatgt
     1081 ttctattcgt cagtccggtt ctatatgttg ttcacgcatt ccttgatggt gttagcttct
     1141 ttattgcaga cgtcttaaat atttcaatag gaaacacatt ttcaggaggt gtaatcgatt
     1201 tcactttatt tggaattttg caggggaacg ctaagacgaa ttgggttctt cagattccaa
     1261 ttggacttat ttggagtgtt ttgtattata ttatttttag atggttcatt actcaattca
     1321 acgttctaac gccaggacga ggagaagaag tagattctaa agaaatttct gaatccgcag
     1381 attcaacttc aaatactgca gattatttaa aacaggatag cctacaaatt atcagagcct
     1441 tgggtggatc aaataatata gaagatgtag atgcttgtgt gacacgttta cgtgtagctg
     1501 taaaagaagt taatcaagtt gataaagcac ttttaaaaca aattggtgca gttgatgtct
     1561 tagaagtgaa gggtggcatt caagcaatct atggagcaaa agcaatctta tataaaaata
     1621 gtattaatga aattttaggt gtagatgatt aagtacttac tgacttaata aaaaacagag
     1681 gagagtgatg gatgagtagg atgaaatgaa atcgcataca agaaataaag aactcattat
     1741 ccaagttgga tacgcttatt acataggaga atacaaatga aatttagaaa attagcttgt
     1801 acagtacttg cgggtgctgc ggttcttggt cttgctgctt gtggcaattc tggcggaagt
     1861 aaagatgctg ccaaatcagg tggtgacggt gccaaaacag aaatcacttg gtgggcattc
     1921 ccagtattta cccaagaaaa aactggtgac ggtgttggaa cttatgaaaa atcaatcatc
     1981 gaagcgtttg aaaaagcaaa cccagatata aaagtgaaat tggaaaccat cgacttcaag
     2041 tcaggtcctg aaaaaatcac aacagccatc gaagcaggaa cagctccaga cgtactcttt
     2101 gatgcaccag gacgtatcat ccaatacggt aaaaacggta aattggctga gttgaacgac
     2161 ctcttcacag atgaatttgt taaagatgtc aacaatgaaa acatcgtaca agcaagtaaa
     2221 gctggagaca aggcttatat gtatccgatt agttctgccc cattctacat ggcaatgaac
     2281 aagaaaatgt tagaagatgc tggagtagca aaccttgtaa aagaaggttg gacaactgat
     2341 gattttgaaa aagtattgaa agcacttaaa gacaagggtt acacaccagg ttcattgttc
     2401 agttctggtc aagggggaga ccaaggaaca cgtgccttta tctctaacct ttatagcggt
     2461 tctgtaacag atgaaaaagt tagcaaatat acaactgatg atcctaaatt cgtcaaaggt
     2521 cttgaaaaag caactagctg gattaaagac aatttgatca ataatggttc acaatttgac
     2581 ggtggggcag atatccaaaa ctttgccaac ggtcaaacat cttacacaat cctttgggca
     2641 ccagctcaaa atggtatcca agctaaactt ttagaagcaa gtaaggtaga agtggtagaa
     2701 gtaccattcc catcagacga aggtaagcca gctcttgaat accttgtaaa cggatttgca
     2761 gtattcaaca ataaagacga caagaaagtc gctgcatcta agaaattcat ccagtttatc
     2821 gcagatgaca aagagtgggg acctaaagac gtagttcgta caggtgcttt cccagtccgt
     2881 acttcatttg gaaaacttta tgaagacaaa cgcatggaaa caatcagcgg ctggactcaa
     2941 tactactcac catactacaa cactattgat ggatttgctg aaatgagaac gctttggttc
     3001 ccaatgttgc aatctgtatc aaatggtgac gaaaaaccag cggatgcttt gaaagccttc
     3061 actgaaaaag caaacgaaac aatcaaaaaa gctatgaaac aatagtcctt agttattcta
     3121 tgaaaaagta attttttaaa gaacctaaga gtgtataccc ccttttccct ctacacagat
     3181 agtgtaagaa aagggggctt ttgtttaaaa tgtaagaaac tgtcacgaaa ttaaaatgaa
     3241 gttcttacat aagcgaatca taaaaaattt cattttgatt ttaaaacagt tcaagaaagt
     3301 caaaaaatta ttctatttga aagagaggtg ccgactgtga aagtcaataa aatccgtatg
     3361 cgggaaacag tgatttccta cgctttccta gcaccagtat tattcttctt tgtcatcttt
     3421 gtgttggctc cgatggtgat gggcttcatt acaagtttct ttaactactc aatgactaaa
     3481 tttgagtttg taggcttgga taactatatc cgtatgttta aagatcctgt ctttacaaaa
     3541 tctctgatta acacagttat tttggttatt ggatctgtac cagttgttgt tctattctca
     3601 ctctttgtag catctcagac ctatcatcaa aatgtcattg ccagatcctt ctaccgtttc
     3661 gtcttcttcc ttcctgttgt aacgggtagt gttgccgtga cagttgtttg gaaatggatt
     3721 tatgacccac tatcagggat tctaaacttt gtccttaagt caagccacat catcagccaa
     3781 aacatttctt ggttgggaga taaaaactgg gcattgatgg cgattatgat tattctcttg
     3841 accacttcag ttggtcagcc catcatcctt tatatcgctg ccatggggaa tattgacaat
     3901 tcactggttg aagcggcgcg tgttgatggt gcaactgagt ttcaagtttt ctggaagatt
     3961 aaatggccaa gccttcttcc aacaactctt tatattgcaa tcatcacaac aattaactca
     4021 ttccagtgtt tcgccttgat tcagcttttg acatctggtg gtccaaacta ctcaacaagt
     4081 accttgatgt actaccttta cgaaaaagcc ttccaattga cagaatacgg ctatgccaac
     4141 acaattggtg tcttcttggc agtcatgatt gctatcgtaa gctttgttca atttaaagta
     4201 cttggaaacg acgtagaata ctaaagaaag gagacagcta tgcaatctac agaaaaaaaa
     4261 ccattaacag cctttactgt tatttcaaca atcattttgc tcttgttgac tgtgctgttc
     4321 atctttccat tctactggat tttgacaggg gcattcaaat cacaacctga tacaattgtt
     4381 attcctcctc agtggttccc taaaatgcca accatggaaa acttccaaca actcatggtg
     4441 cagaaccctg ccttgcaatg gatgtggaac tcagtattta tctcattggt aaccatgttc
     4501 ttagtttgtg caacctcatc tctagcaggt tatgtattgg ctaaaaaacg tttctatggt
     4561 caacgcattc tatttgctat ctttatcgct gctatggcgc ttccaaaaca agttgtcctt
     4621 gtaccattgg tacgtatcgt caacttcatg ggaatccacg atactctctg ggcagttatc
     4681 ttgcctttga ttggatggcc attcggtgtc ttcctcatga aacaatttag tgaaaatatt
     4741 cctacagagt tgcttgaatc agctaaaatc gacggttgtg gtgagattcg taccttctgg
     4801 agtgtagcct tcccgattgt gaaaccaggg tttgcagccc ttgcaatctt taccttcatc
     4861 aatacttgga atgactactt catgcaattg gtaatgttga cttcacgtaa caatttgacc
     4921 atctcacttg gggttgcgac catgcaggct gaaatggcaa ccaactatgg tttgattatg
     4981 gcaggagctg cccttgctgc tgttccaatc gtcacagtct tcctagtctt ccaaaaatcc
     5041 ttcacacagg gtattactat gggagcggtc aaaggataat actctgagaa aatctcttca
     5101 aactacgtca gcgtcacctt gccatactta agtattgcct gcggttagct tcctagtttg
     5161 ttcttcaatt ttcattgagt ataggaaaat caatctatca agatacagaa gtatatttta
     5221 tagatttaga gaatatagag gttataagtg tctacaaaat ggagggtatg cagttacttt
     5281 atgaagtttt gtcagacact tataaactta agaatggttt tagttaacta tcagaaacga
     5341 aggaaagagt atgatttttg acgatttgaa aaacatcacc ttttacaaag ggattcatcc
     5401 caatttagac aaggctatcg actatctcta ccaacatcgt aaagattcat tcgaattagg
     5461 aaagtatgag attgatggag ataaagtctt tctagttgtt caggaaaatg tcctcaatca
     5521 agttgagaat aatcaatttg aacaccataa gaactatgca gatttgcatt tgctggtaga
     5581 aggacatgaa tattcgagct acggttcacg tatcaaagac gaggcagtag cattcgacga
     5641 agcgactgac attggctttg ttcattgtca tgaacactac ccactcttgt tgggttatca
     5701 taattttgcg attttcttcc caggtgagcc acatcagcca actggctatg caggtatgga
     5761 agaaaaggtt cgaaaatatc tctttaaaat tttgattgat taaaaatagg atgaattgtt
     5821 tttttgtaaa gctttgacaa tactctacca tgaaattgat ctttgtgagg tagagaaatg
     5881 agaataaaat atttaaaaat tggtatcttc taagcatgct gcaagagcta gtttcttaga
     5941 tggacagggg attacagttg atgagatgtc ctggataatt aatggcattg tgaatgcatt
     6001 gattggtaga tacataaaat taggtactta tgcagctaag tatggtatta gtatagcacg
     6061 ctcgatctta agtagggcag ctgcaactgc agcagcaaga gtaggattac tgaccaagat
     6121 ttctggatgg attttacgag tagctgtgaa tgtagctgat gtatatggta attttgccaa
     6181 caatattgct gcagcttggg atgcatatga taaaattcct aacaatggtc gtataaactt
     6241 ttaaaatgcg agaatgaaag cactttgtat ttttttattg aatatgttag cttggacagt
     6301 gcttgcaatg ataattcgtg gagggctaga tggatttgat aggcatactt ggagtactat
     6361 tttaattgct tcgctgttcg gggtatatga ttataagccc atagataaaa atagaaaaaa
     6421 gtccaaaaga aaaaagaaaa aatagatttg ttcatggtag ggacttatga aagctttact
     6481 gacaaaaaag aaaacagttt acaaagaaaa atgatggagg agcaaacatg gcacaaaaag
     6541 gagtaagcct tatcaaggca gcatttgata cagataactt tctcatgcgt tttagtgaga
     6601 aggtcttgga catcgtgaca gccaatcttc tttttgtcgt ctcttgtttg cccatcgtga
     6661 cgattggagt ggctaaaatc agcctctacg agaccatgtt cgaagttaag aagagcagac
     6721 gggtgcctgt ttttaaaatc tatctaagat ctttcaagca aaatctgaaa ctaggtcttc
     6781 agttaggtct gcttgagttg ggcattgttt cattaagcct cctagatctt tatctctttt
     6841 ggggtcaaac agctctgccc tttcaattgc tgaaagctat ttgtctaggc attctgattt
     6901 tccttacgat tgtgatgttg gctagctatc caatcgcggc acgttatgat ttaacttgga
     6961 aagaaattct tcaaaaagga ttgatgttgg ctagttttaa ctttccttgg ttcttcctca
     7021 tgttagccat tcttgtcctc attgtgatgg ttctttatct gtctgccttc agtctactct
     7081 taggtggctc agtcttcctg ctttttgggt ttggactatt ggtctttatc cagactggat
     7141 tgatggagaa aattttcgca aaataccaat aggagcctta tttctgaaac tactttcaaa
     7201 ggctccaaac gctattctat aagcgagaaa ctaaaatcta agtgtctata agatattgaa
     7261 agccttttcg gtaaagtgta tactaaagaa gtaaagaaaa atctgcttta gcagaaaata
     7321 aaaataatag gagaaaatct atgtcagatt tgaaaaaata cgaaggtgtc attccagcct
     7381 tctacgcatg ttatgatgag caaggagaag taagtccaga gcgtacgcgt gccttggttc
     7441 aatacttcat tgataaaggt gttcaaggtc tttatgtcaa tggttcttct ggtgaatgta
     7501 tctaccaaag cgttgaagat cgcaagttga ttttggaaga agtcatggcg gtagccaaag
     7561 gtaaattgac cattattgcc catgttgctt gcaataatac taaagatagt atggaacttg
     7621 ctcgccatgc tgaaagcttg ggagtagatg ctattgcaac gattccacca atttacttcc
     7681 gcttgccaga atactcagtt gccaaatact ggaacgatat tagttctgca gctccaaaca
     7741 cagactacgt gatttacaac attcctcaat tggcaggggt tgctttgact ccaagccttt
     7801 acacagaaat gttgaaaaat cctcgtgtta tcggtgttaa gaactcttct atgccagttc
     7861 aagatatcca aacctttgtc agccttggcg gggaagacca tattgtcttt aacggtccag
     7921 atgaacagtt cctaggtggc cgcctcatgg gtgctaaggc tggtatcggt ggtacttatg
     7981 gtgctatgcc agaactcttc ttgaaactca atcagttgat tgcggataag gacctagaaa
     8041 cagcgcgtga attgcagtat gctatcaacg caatcattgg taaactcact tctgctcatg
     8101 gaaatatgta cggtgtcatc aaagaagtct tgaaaatcaa tgaaggcttg aatattggat
     8161 ctgttcgttc accattgaca ccagtaactg aagaagatcg tccagttgta gaagcggctg
     8221 cagccttgat tcgtgaaacc aaggagcgct tcctctaatc taaaaggagg tatttatgac
     8281 atactacgtt gcaattgata tcggtggaac taacatcaag tatggtttgg ttgatcaaga
     8341 ggggcaactt cttgaatcgc atgaaatgcc aactgaggcg cataagggtg gacctcatat
     8401 cttacaaaag accaaagata tcgtagctag ttatttagaa aaaggcccag tagcaggtgt
     8461 tgccatatct tctgctggga tggtggatcc ggataagggt gagattttct atgctgggcc
     8521 gcaaatccct aactacgcag gcacccagtt caaaaaggaa atcgaagaaa gctttactat
     8581 tccttgtgag attgaaaatg atgtcaactg tgcaggtctt gctgaggcag tatctggttc
     8641 aggcaaggga gcaagtgtga cactttgctt gaccattgga acaggtatcg gtggttgctt
     8701 gattatggat aggaaagtct tccatggttt tagtaattca gcctgtgaag tcgggtatat
     8761 gcatatgcag gatggagctt ttcaagactt ggcttctaca acagctttag tgaaatatgt
     8821 agctgaagcc catggagaag atgttgatca gtggaatggc cgacgtatct ttaaggaagc
     8881 tactgaagga aacaaaatct gcatggaagg tattgaccgt atggttgact atctaggaaa
     8941 aggtctggca aatatttgct acgttgccaa tccagaagtg gttattcttg gtggtggtat
     9001 catggggcaa gaggctatcc tcaaacctaa gatccgcaca gccttgaaag aggctttggt
     9061 accaagttta gcagaaaaaa cacgattaga atttgcccat caccaaaata cagcagggat
     9121 gttgggtgca tattatcatt ttaagacaaa acaatcctag tttggctcag ccaaactagg
     9181 attttcttac acgtttttgt ctacgatagc cgttgagttt tttattttcc cagtagctat
     9241 taaagatttt ttccttgctt tcgcgattga tttccaaaaa gtaggcataa atcaaatcga
     9301 taaagaagag cataggaagt tgagcggata ttcgttggat ataggagggt tggctgtggg
     9361 tggctacaag aacagtctct gtataggtct ggctatcttt attgggaaca cttgtaaaga
     9421 gtacagtctt tgcccccatc tccttggcat ctattagact atctaaaata gaaggagttg
     9481 agcctgaaag tgagaagccc agtactagac aattttcatc catgatgctg gttgtccagg
     9541 caaagccgtc ttggtctgtc aaagcttcgc agaccacacc tagtcgcata aaacgtaatt
     9601 tcatttcacg ggcgacgagg ccagaactcc ctgttccgaa gaagtagata cgctcagcat
     9661 cttcgattag ctgggcaatt cgttctagtt ggatttcgtc aatcaagtct tgtgtttgtt
     9721 ccctcatgtt gctataactt ctgaggactc gtttggtcag tggactgtgc ttggagactt
     9781 ggttggcttg attttctgcc tgatgttggt attggaaaat aaattctcgg tagccagtaa
     9841 agccacactt tttagcaaag cgggtcaaag cagcttgaga aatatgtaat ttttgggtga
     9901 cttgttgaga agataaatca tctgtaatcg tttcagcttg caaaaaatag cgagcgattt
     9961 cttgttctag gtctgtcatt tcttcaaaat gtgaatcaat gatagttgcg atatctggtt
    10021 tgtccatagg gaaagctcct ttacatgagt catactggaa gactagatca gggaatagtc
    10081 acacttcatt ataacacata atataaggat agataaataa aaacgcatct ctgttttaaa
    10141 aacgaaaaaa tcgaaaaagc ttctctcttt tccataattt tctactcaaa ttgtggtaca
    10201 attaagagta agattttaag ttagaaatga gactgatttg tatgagaaaa tttaacagcc
    10261 attcgattcc gattcggctt aatttattgt tttcaatcgt cattttactc tttatgacca
    10321 ttattggtcg tttgttgtat atgcaggttt tgaacaagga tttttacgaa aaaaagctag
    10381 cctcagctag tcagaccaag attacaagca gttcagcccg tggggaaatt tatgatgcta
    10441 gtggaaaacc tttggtagaa aatacgttaa agcaggttgt ttcctttacg cgtagcaata
    10501 aaatgacagc tacagactta aaagaaacag ctaaaaagtt actgacttat gtgagcatca
    10561 gttctccaaa tttgacagaa cgccagctgg cggattacta tttggctgat cctgaaatct
    10621 ataaaaaaac agtggaagct ctcccaagcg agaaacgctt ggattcagat ggcaatcgtc
    10681 tatccgaatc agaactgtat aacaatgcgg tcgatagtgt acaaacgagt caactaaact
    10741 atacagagga tgaaaagaaa gaaatctatc tttttagtca gttaaatgct gttggaaact
    10801 ttgcgacagg aaccattgcg acagatcctc taaatgattc tcaggtggct gttattgcct
    10861 ctatttcaaa ggagatgcct ggcattagta tttctacttc ttgggataga aaggttttgg
    10921 aaacttccct ttcttctata gttgggagtg tatccagtga aaaagctggt ctcccagcgg
    10981 aagaagcaga agcctatctt aaaaaaggct attctctaaa tgatcgtgta ggaacttcct
    11041 atttggaaaa gcaatatgaa gagaccttac aaggaaaacg ctcggtaaaa gaaatccatc
    11101 tggataaata tggcaatatg gaaagcgtgg atacaattga ggaaggtagt aagggaaaca
    11161 atatcaaact gaccattgat ttggctttcc aagatagcgt ggatgcttta ctgaaaagtt
    11221 atttcaattc cgagctagaa aatggtggag ccaagtattc tgaaggtgtc tatgcagtcg
    11281 cccttaaccc aaaaacaggt gcggttttgt ctatgtcagg gattaaacat gacttgaaaa
    11341 cgggagagtt gacgcctgat tccttgggaa cggtaaccaa tgtctttgtt ccaggttcgg
    11401 ttgtcaaggc ggcgaccatc agctcaggtt gggaaaatgg agtcttgtca ggaaaccaga
    11461 ccttgacaga ccagtccatt gtcttccaag gttcagctcc catcaattct tggtatactc
    11521 aggcttacgg ttcattccct atcacagcgg tccaagctct ggagtattca tcaaatacct
    11581 atatggtcca aacagcctta ggtcttatgg ggcaaaccta tcaacccaat atgtttgtcg
    11641 gcaccagcaa tctagagtct gctatggaga aactgcgttc aacctttggc gaatatggct
    11701 tgggtactgc gacaggaatt gacctaccag atgaatctac tggatttgtt cccaaagagt
    11761 atagctttgc taattacatt actaatgcct ttgggcagtt tgataactat acgccgatgc
    11821 agttggctca gtatgtagca actattgcaa ataatggtgt tcgtgtggct cctcgtattg
    11881 ttgaaggcat ttatggtaat aatgataagg gaggactggg taacttgatt cagcaactgc
    11941 aaccgacaga gatgaataag gtcaatatat ccgactccga tatgagcatc ttgcaccaag
    12001 gtttttatca ggttgcccat ggtactagtg gattgacaac tggacgtgcc ttttcaaatg
    12061 gtgccttggt atccattagc ggaaaaacag gtacagccga aagctatgtg gcagatggtc
    12121 agcaagcaac caataccaat gcggtggcct atgccccatc tgataatccc caaatcgctg
    12181 tcgcagtggt ctttcctcat aataccaatc taacaaatgg tgtaggacct tccattgcgc
    12241 gtgacattat caatctgtat caaaaatacc atccaatgaa ttagaaagga aattatgctt
    12301 tatccaacac ctattgccaa gttgattgac agttattcta agttaccagg tatcgggatt
    12361 aagacggcta cgcgtctggc cttttatacg attgggatgt ctgctgatga tgtcaatgaa
    12421 tttgcaaaaa atctcctttc tgctaagaga gaattgacat attgttctat ttgtggacgt
    12481 ttgacagacg acgatccttg ttctatctgt actgatccga ctcgtgacca gacaacaatt
    12541 ttagttcttg aggatagtag agatgtggca gccatggaaa atatccaaga ataccatgga
    12601 ctctatcatg tccttcatgg cctcatttct cctatgaatg gtatcagtcc ggacgatatc
    12661 aatctcaaga gccttatgac tcgtcttatg gatagtgagg tttcagaagt gattgtggcg
    12721 actaatgcta cagcggatgg tgaagcgact tccatgtatc tttcacgttt gctcaagccg
    12781 gctggtatca aggttacgcg tctagcacga ggtctcgctg tgggagcgga cattgagtat
    12841 gcggacgaag tgacactctt acgagcgatt gaaaatcgga cagagttgta agtgtaggca
    12901 aatttacgaa ctccattcat ttataaaaaa tcaaagaggc tgaaaatcgt tcctatcggc
    12961 ctctttttgt atagtgtgat gagtaggatc aggttcaagt tttaaaaaac caagcaaata
    13021 tgatatacta aagagcgagt attctagtag aattaggaca aataagtaga attaggacaa
    13081 ataatatgaa acaaacgatt attcttttat atggtggacg gagtgcggaa cgcgaagtct
    13141 ctgtcctttc agctgagagt gtcatgcgtg cggtcaatta cgaccgtttc acagtcaaga
    13201 ctttctttat cagtcagtca ggtgacttta tcaaaacaca ggaatttagt catgctccgg
    13261 ggcaagaaga ccgtctcatg accaatgaaa ccattgattg ggataagaaa gttgcaccaa
    13321 gtgctatcta cgaagaaggt gcagtggtct ttccagtcct tcacgggcca atgggagaag
    13381 atggctctgt tcaaggattc ttggaagttt tgaaaatgcc ttacgttggt tgcaacattt
    13441 tgtcatcaag tcttgccatg gataaaatca cgactaagcg tgttctggaa tctgctggta
    13501 ttgcccaagt tccttatgtg gctatcgttg aaggcgatga tgtgactgct aaaatcgctg
    13561 aagtggaaga aaaattggct tatccagtct tcgctaagcc gtcaaacatg gggtctagtg
    13621 tcggtatttc taagtctgaa aaccaagaag aactccgtca agccttaaaa cttgccttcc
    13681 gatatgacag ccgtgtcttg gttgagcaag gagtgaatgc ccgtgaaatt gaggttggcc
    13741 tcttgggtaa ctacgatgtc aagagcacgc tacctggaga agttgtcaag gacgttgcct
    13801 tttatgacta cgatgccaag tatattgata acaagattac tatggatatt cctgccaaaa
    13861 tcagtgatga tgtggtggct gtcatgcgtc aaaatgcaga aacagccttc cgtgccattg
    13921 gtggccttgg tctatctcgt tgcgatttct tctatacaga taagggagag atttttctca
    13981 acgagctcaa taccatgcca ggtttcaccc agtggtctat gtacccacta ctttgggaca
    14041 atatggggat cagctaccca gaactaatcg agcgtttggt tgaccttgcc aaggaaagtt
    14101 ttgacaagcg cgaagcgcat ttgatataaa atgaaagaga gggtagaagc cagaaccatc
    14161 actgcaaggt gactagagtt ctcggacttc gccccttttt aaaggagtag aaatgaaatt
    14221 aacaatctat gaagttgccc aagctgttgg agctaaaaat gatgttagtc tttttgcgga
    14281 cgcccagtta gaaaaggctg agtttgacag tcgattgatt gggactggag atttatttgt
    14341 gccacttaaa ggtgcgcttg atggccatga ctttattgaa acagcctttg aaaatggtgc
    14401 agcagtaacc ttgtctgaga aagaggtctc aaatcatcct tacattctag tagatgatgt
    14461 tttgacagcc tttcaatcct tagcatccta ctatcttgaa aaaacgactg ttgatgtctt
    14521 tgctgttaca ggttcaaatg gcaagacaac gactaaggat atgttggcgc atttactgtc
    14581 aacaagatac aagacctaca aaacacaagg caattacaat aatgagattg gccttcctta
    14641 cacagttctt catatgcctg aaggaacaga aaagttggtt ttggagatgg gacaggatca
    14701 cttgggagat attcatctct tgtctgaatt ggctcgtcca aaaacagcca tcgtgacctt
    14761 ggttggagaa gctcatttgg cctttttcaa agatcgttct gagattgcta aaggaaaaat
    14821 gcaaattgca gacggaatgg cttcaggttc cttgctttta acgccggctg accctatcgt
    14881 agaggactat ttgccaactg ataaaaaggt ggtccgtttt gggcaagggg cagagttgga
    14941 aatcacagac ttggttgagc gtaaggacag tctgaccttt aaggctaatt tcttggaaca
    15001 agcccttgat ttgccagtga ctggtaagta caatgctacc aatgctatga ttgcgtccta
    15061 tgttgcccta caagaaggag tttcagagga gcaaattcat caggccttcc aaggtcttga
    15121 attgacgcgt aatcgtactg agtggaagaa agcagccaat ggagcagata tcctgtcaga
    15181 cgtatataat gccaatccaa ctgctatgaa gctgatttta gagactttct ctgccattcc
    15241 agccaatgaa ggtggcaaga aaattgcagt gttggcggat atgaaggagc ttggtgacca
    15301 gtctattcaa ctccataacc agataatttt gagcctttct ccagatgtgc ttgataccgt
    15361 tattttctat ggagaagaca ttgctgaatt agcccaactt gctagtcaaa tgttcccaat
    15421 cggacacgtt tattacttca agaaaacaga agaccaagac caatttgaag acctagttaa
    15481 gcaggtcaaa gaaagccttg gggctcatga ccaaatcctg ctcaaaggct ctaactctat
    15541 gaatctagcc aagttggtag aaagtttaga aaatgaagac aagtgatttt gtcaagtatt
    15601 tgcaaagaat gattgccatt acagatactg gcttaacctt tacaaaagat ccgtttgacc
    15661 gtgagcgcta cgaagacttg cgagactttt tatctgaaat gttgaatcaa gcatcagacc
    15721 ttgattccga agaagtggca gaagtcttga agccaacttc tgcttatgcg actccgttaa
    15781 tggacgtccg tgcttggatt gttgaggacg aaaagatttg tctggttagg ggacaaggag
    15841 aggatagttg ggctttgcca ggtggctttg gtgaggttgg ctattctcca acagaaaata
    15901 ttctcaagga aattgaagaa gaaaccggtt ttaaagccaa agttgaaaga ctgctagctg
    15961 tttttgatac caatcgtttc caactacaga gcaaacagta tacaaagttt gtttttggat
    16021 gtaagcttct cgatggacaa ttccaagaaa atcaagaaat tgctgacctt caattttttg
    16081 ccattgacca actgccgaac ttatctgaaa aacgcattac caaggagcaa atagagcttc
    16141 tttggcaggt ttatcaaggt catagggggc aatatcttga ctaagaagat gattatcgta
    16201 tttctaaatc catttttaac aactagcatg gtataataat atgcaggaaa attttgaatt
    16261 atgaggaaga ctagatgaat ttatgggata ttttctttac gactcaggca accgagccgc
    16321 ccaaatttga ccttttttgg tatgttagcc tatttacgct cttagcctta accttttata
    16381 cagcccatcg ctatcgtgaa aagaaggttt accaacgatt tttccaaatc ttgcagactg
    16441 ttcagttaat ccttctttat ggttggtact gggttaatca tatgccactg tcagaaagcc
    16501 taccctttta ccattgccgt atggctatgt ttgtggtact cttgcttcct ggtcagtcca
    16561 aatataaaca atactttgca ttattgggaa catttgggac attagcagcc tttgtttatc
    16621 cagtgccaga tgcttaccct tttccacata ttaccatttt atcctttatc tttggtcatt
    16681 tagcactctt ggggaactct ctagtttatc tattgagaca gtataatgcg cgattgctgg
    16741 atgtgaaggg aatttttctc atgacctttg ccctaaatgc cttgattttt gtggtcaatt
    16801 tggtgacagg tggcgattac ggatttttga caaaaccgcc attggttggg gatcacggtc
    16861 tagtagctaa ttatttactt gtttcaattg tgctggtagc tactatcagt ttgactaaga
    16921 aaatcttaga attcttttta gctcaagaag cagaaaaaat gattgcaaag gaagcttaac
    16981 acagagcttt cttttttgct cttagagagt ttttacaagc agcttataaa ataagaattt
    17041 ctgaatagac aaactcaaaa aatggctggg aaatttagga aaaaagcaag cacgattaaa
    17101 ttttttgtgt tataatattt tgtgaatagc tatgcctatg tttagctatg gaataatacg
    17161 aagtgcgaaa cttggaagat agagaggaag cgatgtaatg gctagagaag gcttttttac
    17221 aggtctagat attggaacaa gctctgtcaa ggtgcttgtg gccgagcaga gaaatggtga
    17281 attaaatgta attggcgtga gtaatgccaa aagtaaaggt gtaaaggatg gaattattgt
    17341 tgatattgat gcagcagcaa ctgctatcaa gtcagccatt tcccaagcgg aagaaaaggc
    17401 aggcatttcg attaaatcag tgaatgtcgg cttgcctggt aatcttttgc aggtagaacc
    17461 aactcagggg atgattccag taacatctga tactaaggaa attacggatc aagatgttga
    17521 aaatgttgtc aaatcagctt tgacaaagag tatgacacct gaccgtgaag tcattacctt
    17581 tattcctgaa gaatttattg tggatggttt ccaagggatt cgtgacccac gtggcatgat
    17641 gggggttcgc cttgaaatgc gtggtttgct ttatacagga cctcgtacta tcttgcacaa
    17701 tttgcgtaag acggttgagc gtgcaggtgt tcaggttgaa aatgttatca tttcaccact
    17761 agcaatggtt cagtctgttt tgaacgaagg ggaacgtgaa tttggtgcta cagtgattga
    17821 tatgggggca ggtcaaacga ctgtcgctac aatccgtaat caagaactcc agttcacaca
    17881 tattctccaa gaaggtggag attatgtaac taaagatatc tccaaggttt tgaaaacctc
    17941 tcgcaaatta gcggaaggct tgaaactgaa ttacggggaa gcctatccgc ctcttgcaag
    18001 caaagaaacc ttccaagtag aggttattgg agaagtagaa gcagtcgaag tgacggaagc
    18061 ctacttgtca gaaattattt ctgcacgaat caagcacatc cttgaacaaa tcaagcaaga
    18121 attagataga aggcgtctat tggacctccc tggtggtatt gtcttaatcg gtgggaatgc
    18181 cattttacca ggtatggttg agcttgctca ggaagtcttt ggcgtccgtg tcaagcttta
    18241 tgtcccaaat caagttggta tccgtaatcc agcctttgcg catgtgatta gtttatcaga
    18301 atttgcgggt caattaacag aagttaatct tttggctcag ggagcgataa aaggtgagaa
    18361 tgacttaagt catcagccaa ttagttttgg tgggatgctg caaaaaacag ctcagtttgt
    18421 acaatcaacg cctgttcaac cagctcctgc tccagaagta gagccggtgg cgcctacaga
    18481 accaatggcg gatttccaac aagcttcaca aaataaaccg aaattagcag atcgtttccg
    18541 tggcttgatc ggaagcatgt ttgacgaata aagaggaaaa ataaattatg acattttcat
    18601 ttgatacagc tgctgctcaa ggggcagtga ttaaagtaat tggtgtcggt ggaggtggtg
    18661 gcaatgccat caaccgtatg gtcgacgaag gtgttacagg cgtagaattt atcgcagcaa
    18721 acacagatgt acaagcattg agtagtacaa aagctgagac tgttattcag ttgggaccta
    18781 aattgactcg tggtttgggt gcaggaggtc aacctgaggt tggtcgtaaa gccgctgaag
    18841 aaagcgaaga aacactgacg gaagctatta gtggtgccga tatggtcttc atcactgctg
    18901 gtatgggagg aggctctgga actggagctg ctcctgttat tgctcgtatc gccaaagatt
    18961 taggtgcgct tacagttggt gttgtaacac gtccctttgg ttttgaagga agtaagcgtg
    19021 gacaatttgc tgtagaagga atcaatcaac ttcgtgagca tgtagacact ctattgatta
    19081 tctcaaacaa caatttgctt gaaattgttg ataagaaaac accgcttttg gaggctctta
    19141 gcgaagcgga taacgttctt cgtcaaggtg ttcaagggat taccgatttg attaccaatc
    19201 caggattgat taaccttgac tttgccgatg tgaaaacggt aatggcaaac aaagggaatg
    19261 ctcttatggg tattggtatc ggtagtggag aagaacgtgt ggtagaagcg gcacgtaagg
    19321 caatctattc accacttctt gaaacaacta ttgacggtgc tgaggatgtt atcgtcaacg
    19381 ttactggtgg tcttgactta accttgattg aggcagaaga ggcttcacaa attgtgaacc
    19441 aggcagcagg tcaaggagtg aacatctggc tcggtacttc aattgatgaa agtatgcgtg
    19501 atgaaattcg tgtaacagtt gttgcaacgg gtgttcgtca agaccgcgta gaaaaggttg
    19561 tggctccaca agctagatct gctactaact accgtgagac agtgaaacca gctcattcac
    19621 atggttttga tcgtcatttt gatatggcag aaacagttga attgccaaaa caaaatccac
    19681 gtcgtttgga accaactcag gcatctgctt ttggtgattg ggatcttcgc cgtgaatcga
    19741 ttgttcgtac aacagattca gtcgtttctc cagtcgagcg ctttgaagcc ccaatttcac
    19801 aagatgaaga tgaattggat acacctccat ttttcaaaaa tcgttaagta aatgaatgta
    19861 aaagaaaata cagaacttgt ttttcgagaa gttggagagg ctagtctgag tgctcatcga
    19921 gagagtagtt cggtctctgt cattgcagtt accaagtatg tagatgtacc gacagcggaa
    19981 gccttgcttc cgctaggtgt tcatcatatc ggtgaaaatc gtgtagataa gtttctggaa
    20041 aaatatgaag ctttaaaaga tcgagatgtg acttggcatt tgattggtac cttgcaaaga
    20101 cgtaaggtga aagatgtcat tcaatacgtt gattatttcc atgcattgga ctcagtaaag
    20161 ctagcagggg aaattcaaaa aagaagtgac cgagtcatca agtgtttcct tcaagtaaat
    20221 atttctaaag aagaaagcaa acacggtttt tcgagagagg aactgctgga aatcttgcca
    20281 gagttagcca gactagataa gattgaatat gttggtttaa tgacgatggc accttttgag
    20341 gctagcagtg agcagttgaa agagattttc aaggcgaccc aagatttaca aagagaaatt
    20401 caagagaaac aaattccaaa tatgcctatg accgagttaa gtatgggaat gagtcgtgat
    20461 tataaagaag cgattcaatt cggttccact tttgttcgta taggtacatc attttttaag
    20521 taggagagaa ccatgtcttt aaaagataga ttcgatagat ttatagatta ttttacggag
    20581 gatgaggatt caagtctccc ttatgaaaaa agagatgagc ctgtgtttac tccagtaaat
    20641 tcttcacagg aaccggctct cccaatgaat caaccttcac agtcggttgg tacaaaagag
    20701 aacaatatca ccagacttca tgcaagacaa caggaattgg caaatcagag tcagcgtgca
    20761 acggataagg tcattataga tgttcgttat cctagaaaat atgaggatgc aacagaaatt
    20821 gttgatttat tggcaggaaa cgaaagtatc ttgattgatt ttcagtatat gacagaggtg
    20881 caggctcgtc gttgtttgga ctatttggat ggagcttgtc atgttttagc tggaaatttg
    20941 aaaaaggtag cttctaccat gtatttgttg acaccagtga atgttattgt aaatgttgaa
    21001 gatatccgtt taccagatga agatcaacag ggtgagttcg gttttgatat gaagcgaaat
    21061 agagtacgat aatgattttt ttaattcgta tgatttataa tgcagtggat atttactccc
    21121 tgattttggt agccttcgct gtcatgtctt ggtttccagg tgcctacgaa tccagtttag
    21181 gtcgttggat tgtagcgttg gtgaaaccag tacttgctcc cttgcaacgc ctgcctttac
    21241 agatagcggg tcttgattta tctgtttggg tcgcgattgt tttggttcga tttttaggag
    21301 aaaacctagt gcgttttctg gcgatgatag gatgaataaa gggatttatc agcatttctc
    21361 catagaagat cgtccatttc ttgacaaggg aatggaatgg ataaagaagg tagaagatag
    21421 ctatgctcct tttttaactc cttttatcaa tcctcatcag gagaagctat taaagatttt
    21481 ggccaaaacc tatggtcttg cttgtagcag tagtggggaa ttcgtctcga gtgagtatgt
    21541 tcgagtttta ttatacccag attatttcca accagagttt tcagattttg aaatatctct
    21601 ccaagaaatt gtgtattcca ataaatttga acatttaacg catgctaaga ttttagggac
    21661 agtcatcaat caattaggga ttgaacggaa actttttgga gatatcctag tagatgaaga
    21721 acgggcgcag attatgatta atcagcagtt tcttcttctc tttcaagatg gactaaagaa
    21781 aattggtcgt atacctgttt cgctggagga acgtcctttc accgagaaaa tagataagct
    21841 agaacagtat cgagaactga atttatctgt gtctagtttt cgattagatg ttcttttatc
    21901 aaatgttttg aaactatcta ggaatcaagc aaaccagttg attgaaaaga aacttgtcca
    21961 agtaaattat catgtggtag acaaatcaga ttacactgtt caagttggag acttgattag
    22021 tgtgagaaaa tttggtcgct tgagattatt tcaagataag ggacaaacga aaaaagagaa
    22081 gaaaaaaata accgtccagt tattattaag taagtgagga atagaatgcc aattacatca
    22141 ttagaaataa aggacaagac ctttggaact cgattcagag gttttgatcc agaagaagtc
    22201 gatgaatttt tagatattgt ggttcgtgat tacgaagatc ttgtgcgtgc gaatcatgat
    22261 aaaaatttgc gtattaagag tttagaagag cgtttgtctt actttgatga aataaaagat
    22321 tcattgagcc agtctgtatt gattgcccag gatacagctg agagagtgaa acaggcggcg
    22381 catgaacgtt caaacaatat cattcatcaa gcagagcaag atgcgcaacg cttgttggaa
    22441 gaagctaaat ataaggcaaa cgagattctt cgtcaagcaa ctgataatgc taagaaagtc
    22501 gctgttgaaa cagaagaatt gaagaacaag agccgtgtct tccaccaacg tctcaaatct
    22561 acaattgaga gtcagttggc tattgttgaa tcttcagatt gggaagatat tctccgtcca
    22621 acagctactt atcttcaaac tagtgatgaa gcctttaaag aagtggttag cgaagtactt
    22681 ggagaaccga ttccagctcc aattgaagaa gaaccaattg atatgacacg tcagttctct
    22741 caagcagaaa tggaagaatt acaagctcgt attgaggtag ccgataaaga attgtctgaa
    22801 tttgaagctc agattaaaca ggaagtggaa actccaactc ctgtagtgag tcctcaagtt
    22861 gaagaagagc ctctgctcat ccagttggcc caatgtatga agaaccagaa gtagctccag
    22921 tgcatccgac aggtccaaca ccagctacag aaactgttga ttcagcatca ggatttgaag
    22981 caccgcaaga atccgttaca attttataag aaacgatgtg agaacaatat cttatcctta
    23041 tatttccagc gagcaggaga tggtgtgagt cctgcattcc ctaacgataa gattatcctc
    23101 tcaaaaactc aagtctgaag ctagtaagat ttgacgtttc ccacgttacg ggataagagg
    23161 gagaaagact aaatcttttt ccgaataaag gtggtaccac gattttcgtc ctttttggaa
    23221 gtcgtggttt ttaatttgtt attatttata aaggagatac catgaaactc aaagataccc
    23281 ttaatcttgg gaaaacagct ttcccaatgc gtgcaggcct tccgaccaaa gagccagttt
    23341 ggcaaaagga atgggaagat gcaaaacttt accaacgtcg tcaagaacta aatgaaggga
    23401 aaccgcattt tgtcttgcat gatggccctc catacgcaaa cggaaatatc cacgttggac
    23461 atgccatgaa tcatatctca aaagatatca tcattcgttc taagtctatg tcaggtttta
    23521 acgcacctta tatcccaggt tgggatactc atggtctgcc aatcgagcaa gttttggcaa
    23581 agcaaggtgt gaagcgcaaa gaaatggact tggttgagta cttgaaactc tgtcgtgagt
    23641 acgctctttc tcaagtttat aaacaacgtg atgatttcaa acgcttgggg atgtcaggtg
    23701 actgggaaaa tttatatgtg actttaactc cagactatga agcagcccaa atccgtgtct
    23761 ttggtgagat ggctaataag ggttatatct accgtggtgc caagccagtt tactggtcat
    23821 ggtcatctga gtcagccctt gccgaagcgg aaattgaata ccatgatttg gtttcgactt
    23881 cactttatta tgccaataag gtaaaagatg gcaaaggtat cctagataca gatacttata
    23941 tcgtagtctg gacaacaact ccatttacca tcacagcttc tcgtggtttg actgttggtg
    24001 cagatattga ttacgttttg gttcaacctg ctagtgaaac tcgtaagttt gtcgttgctg
    24061 cagaattgtt gactagcttg tctgagaaat ttggctgggc tgatgttcaa gtgttggcaa
    24121 cttaccgtgg tcaagaactc aaccacatcg taacagaaca cccatgggat acagctgtag
    24181 atgagttggt aatccttggt gatcacgtta ccactgactc tggtacaggt atcgtccata
    24241 cagcccctgg ttttggtgag gacgactaca atgttggtat tgctaatggt cttgaagtcg
    24301 cagtgactgt tgacgaacgc ggtatcatga tggcgaatgc tggtcctgag tttgaaggtc
    24361 agttctacga caaggttgta ccaactgtta ttgaaaaact tggtaacctc cttctagccc
    24421 aagaagaaat ctctcactca tacccatttg actggcgtac taagaaacca atcatctggc
    24481 gtgcagttcc acaatggttt gcctcagttt caaaattccg ccaagaaatc ttggatgcta
    24541 ttgataaagt taaattccat acagaatggg gtaaagtacg tctatataat atgattcgtg
    24601 accgtggtga ctgggttatc tctcgtcaac gtgcttgggg tgttccactt ccaatcttct
    24661 atgcagaaga cggtacagct atcatgacag ctgagactat tgaacatgtg gcgcaactct
    24721 ttgaagtaca tggttcaagc atttggtggg aacgtgatgc caaaaacctc ttaccagaag
    24781 gatttacaca tccaggttct ccaaatgggg agttcaagaa agaaacagat attatggatg
    24841 tatggtttga ctcaggttca tcatggaatg gtgttttggt aaatcgtcca aatctgactt
    24901 atccagctga cctttacctt gaaggttctg accaataccg tggttggttc aactcatcac
    24961 ttattacatc tgttgccaac catggcgtag caccttacaa acaaatcttg tcacaaggtt
    25021 ttacccttga tggtaaaggt gagaagatgt ctaaatcact tggaaatacc attgctccaa
    25081 gtgatgttga aaaacaattt ggtgcagaaa tcttgcgtct ctgggtaaca agtgttgact
    25141 caagcaatga cgtgcgtatc tctatggata ttttgagcca agtttctgaa acttaccgta
    25201 agattcgtaa cactcttcgt ttcttgattg ccaatacatc tgactttaac ccagctcaag
    25261 atgtagtcgc ttacgatgaa cttcgttcag ttgataagta catgactatt cgctttaacc
    25321 agcttgtcaa gaccattcgt gatgcctatg cggactttga attcttgaca atctacaagg
    25381 ccttggtgaa ctttatcaac gttgacttgt cagccttcta ccttgatttt gccaaagatg
    25441 ttgtttacat tgaaggtgcc aaatcattgg aacgccgtca aatgcagact gttttctatg
    25501 acattcttgt caaaatcacc aaactcttga caccaatcct tcctcacact gcggaagaaa
    25561 tctggtcata tcttgagttt gaagctgaag acttcgttca attgtcagaa ttgccagaag
    25621 ctcaaacttt tgctaatcaa gaagaagtct tggatacatg ggcagccttc atggacttcc
    25681 gtggacaagc tcaaaaagcc ttggaagaag ctcgtaatgc aaaagttatc gggaaatcgc
    25741 ttgaagcaca cttgacagtt tatccaaatg aagttgtgaa aactctactc gaagcagtaa
    25801 acagcaatgt ggctcaactt ttgatcgtgt cagacttgac catcgcagaa gggccagctc
    25861 cagaagctgc tgttagcttc gaagatgtag ccttcacagt tgaacgcgct gcaggtcaag
    25921 tatgtgaccg ttgccgtcgt atcgacccaa caacagcaga acgcagctac caggcagtca
    25981 tctgtgacca ctgtgcaagc atcgtagaag aaaactttgc ggaagcagtc gcagaaggat
    26041 ttgaagagaa ataaggttga aaagtctagg caaaattcaa tttgagaaga aaagacaact
    26101 aattttatag tctattaaac gcattgtatc acgtttttga atacctgata tgatgcgttt
    26161 tttatttatt ttaaaaattt gcgaggtatg actttttata ctcaacaaga atcaaagaga
    26221 aacttagcaa gctaacagta gtaagataaa ataggaattt gatattaggg ataagattgc
    26281 taaatagtgt aatattttta caataataaa tttatatagt tatttttggt ttctgaaaag
    26341 tattatattt tatttcatat tatacaaatt tttattttat aatatcagaa aatacttttt
    26401 ttaaaagcaa atatgataca attttatttg aaaaaaataa aaaaggagat tttattatga
    26461 aattaaaaac acttgcttta attagtggta tcgtcggtct tgtgggagga attttacttc
    26521 ttattggtcc ttttgtcttg ttgggaacag cggtaaacac agttgctaca actcttaatg
    26581 gaggagctac tgcaggggct ttttcaggtg ttgccttact cttgaatgcc ttgaagattg
    26641 caaatcttgt tcttggtatc attgctattg tttactataa aggagataat cgtgtaggtg
    26701 cagctccgtc tgtactaatg attgtttttg gtggagttag tctcattcca ttcttaggat
    26761 gggttggggg gattcttgtt attatcggag gatctctatt ccttgcaaca ttgaagaaat
    26821 tcaaatcaga agaataaaag gtattttagc atgaaaagaa caaaaaagtt tatcggtata
    26881 ggagtagctc tattatctct ttttcttcta gttgcatgtg gaacataaag ttcaaaggat
    26941 acttcaacaa gtaatgatga gaagacagta gcaacatcca atagttcaaa agaaacaatc
    27001 actttcgata caccggttgt aacagacgat gtgattgaat caatacgcac ttatgcagat
    27061 tatatagatc tttataaaaa tatttttgat gattatttta ctaaagctga ggaaggtttc
    27121 aaaggcacag ctatggaaaa taatgactcg tttactaaac taaaagagtc aactcaaaaa
    27181 ttattcgatg cgcagaaaaa aaggttaaat aatgaagata gaatagaaac aactaaaaac
    27241 aatgtgattg ccaaacattg tcaaacagtc ctttcctttt tggttttgac tagctttttt
    27301 gtgaaaaatt gtgtaaaata gaatagataa acgaggggaa acctcggaaa atttaaagga
    27361 gaatccatct aatggtaaaa ttggtttttg ctcgccacgg tgagtctgaa tggaacaaag
    27421 ctaacctttt cactggttgg gctgatgttg atttgtctga aaaaggtaca caacaagcga
    27481 ttgacgctgg taaattgatc aaagaagctg gtatcaaatt tgaccaagct tacacttcag
    27541 tattgaaacg tgctatcaaa acaactaact tggctcttga agcttctgac caattgtggg
    27601 ttccagttga aaaatcatgg cgcttgaacg aacgtcacta cggtggtttg actggtaaaa
    27661 ataaagctga agctgctgaa caatttggtg atgagcaagt tcacatctgg cgtcgttcat
    27721 acgatgtatt gcctccaaat atggaccgtg atgatgagca ctcagctcac acagaccgtc
    27781 gttatgcttc acttgacgac tcagtaatcc cagatgctga aaacttgaaa gtgactttgg
    27841 aacgtgctct tccattctgg gaagataaaa tcgctccagc tcttaaagat ggtaaaaacg
    27901 tattcgtagg agctcacggt aactcaatcc gtgcccttgt aaaacacatc aaaggtttgt
    27961 cagatgacga gatcatggac gtggaaatcc ctaacttccc accattggta ttcgaattcg
    28021 acgaaaaatt gaacgtcgtt tctgaatact accttggaaa ataaaaaatt gtaagtctag
    28081 aattgatttc taggcttttt atgttagtat ggaagtatga taaggaataa aaaacaagat
    28141 tatgtactgg cctacaagca accagtttca accacttaca tgggttggga agaagaagct
    28201 ttaccgatag gcaatggttc tttaggagca aaagtatttg gccttatagg ggctgaacgg
    28261 attcaattta atgaaaaaag tctctggtct ggaggtccac ttcctgatag ttcagattat
    28321 cagggtggaa atcttcagga tcagtatgtt tttttagctg agattcggca ggctttggag
    28381 aagagagatt acaatctggc taaggaactg gctgagcagc acctaattgg gccaaaaacg
    28441 agtcaatatg ggacctatct gtcttttggg gatattcaca ttgagttcag ccagcaaggt
    28501 acgactttgt ctcaggtgac ggactatcag agacagctga atattagtaa ggcacttgtg
    28561 acgacttctt atgtctataa gggaacgcga tttgaacgtg aagcttttgc gagttttcca
    28621 gatgatctct tggttcagcg ttttactaag gaaggggcgg aaactctaga ttttactata
    28681 gaactatcct tgacctgtga tttggcttct gatggaaagt atgagcagga aaaatctgat
    28741 tacaaggagt gtaagttgga tattactgat tctcatatct tgatgaaggg aagagttaag
    28801 gataatgatc tgcggtttgc tagttatcta gcttgggaaa cggatggaga tattagagtt
    28861 tggtcagata gggttcagat atcaggagcc agttatgcca atctcttctt ggccgctaag
    28921 acggattttg cccaaaatcc tgctagcaat tatcgcaaga aactagattt agagcaacag
    28981 gtgatagact tggtggacac agctaaagaa aagggctata cccaattgaa atcaaggcat
    29041 atcgaggact accaagcctt attccagcgt gttcaattgg atttggaagc taatgttgac
    29101 gcattcacta cagatgattt gttaaaaaat tataagccac aagaagggca ggctttggag
    29161 gagctgttct tccagtatgg acggtattta ttgattagtt cgtccagaga ctgcccagat
    29221 gctctaccag ctaacctaca gggagtctgg aatgcggtcg acaatcctcc ttggaattcg
    29281 gactatcact taaatgtcaa tctgcagatg aattattggc cagcctatgt taccaatctc
    29341 ctagaggcgg tctttccggt catcaactat gtagatgatt tgcgtgtcta tggtcgtcta
    29401 gcggctgtaa agtatgcagg aatcgtctct caaaaaggtg aggaaaatgg ttggttggtt
    29461 catactcaag cgactccctt tggttggacg gcacctggtt gggattacta ttggggttgg
    29521 tcaccagctg ccaatgcgtg gatgatgcaa accgtttatg aagcctattc attttatagg
    29581 gaccaagact atctcaggga gaaaatttat cccatgttga gggaaacggt tcgtttttgg
    29641 aatgcctttt tacataagga tcagcaggcg cagcgttggg tgtcttctcc gtcttattcc
    29701 ccagaacatg ggccgatttc gattggcaat acttatgacc aatctctgat ttggcagtta
    29761 tttcatgatt ttattcaggc tgctcaggaa ttgggactgg atgaggactt gttgactgag
    29821 gttaaggaga agtctgattt actaaatcct ttgcaaatca ctcaatctgg tcgaatcagg
    29881 gagtggtatg aggaggaaga gcagtatttt caaaatgaga aagtggaggc ccagcatcgg
    29941 cacgcttccc atctagtggg actctatcct ggcaatctct ttagctacaa gggacaagag
    30001 tatattgaag cggcacgtgc tagcctcaat gatcgtggag atggcggcac aggctggtcc
    30061 aaggctaata agatcaatct ctgggcgcgt ttgggagatg gcaatcgagc ccataaatta
    30121 ttggcagagc agttaaaaac atccaccttg ccaaatcttt ggtgtagcca tcctcctttt
    30181 cagatagatg gtaattttgg tgctactagt ggcatggcag aaatgttact ccagtctcat
    30241 gcagcttatc tggtacctct agctgcccta cctgatgctt ggtcaacagg ttctgtttca
    30301 ggcttaatgg cacgtggaca ttttgaagtg agcatgagct gggaagataa aaaactctta
    30361 cagttgacca ttttatcaag gagtggagga gatttgcgag tttcttatcc agatattgag
    30421 aagagtgtga ttaaaatgaa tcaagaaaaa ataaaagcga aatgcatggg gaaagattgt
    30481 atttcggtgg caacagcaga aggtgatctt gttcaatttt atttttaaga agatgttata
    30541 aggcagtaat ttgaaacttc cttttaataa ggatttaaga atataggcag tttccaacta
    30601 gttgaaaaag cgttataatg ataataggaa gtaatactca atgaaaatca aagagcacaa
    30661 actaggaagc tagccgcagg ttgctcaaaa cagtgttttg aggttgtaga tggaagctga
    30721 cgtggtttga agagagattt tcgaggagta taatttgttt gatagagggt gggtctgatg
    30781 gcttatattg agatgaaaca ctgttacaag cgttatcagg ttggggacac ggagattgtg
    30841 gccaatcgtg atgtgaattt tgagattgaa aagggggagc tggttattat ccttggtgct
    30901 tcaggtgcag gcaagtcaac agttcttaac cttcttgggg gaatggatac caatgatgaa
    30961 ggggaaatct ggattgatgg tgttaatatt gcggattata gttcccacca gcgcaccaat
    31021 taccgtagaa atgatgtggg gtttgttttt cagttttata atctagtttc taatctgaca
    31081 gctaaggaaa atgtggaact ggcttctgaa attgtgacag atgccttgaa tcctgatcag
    31141 gtcttgacag atgtaggtct ggctcatcgt ctcaataact ttccagccca gctttctgga
    31201 ggggagcaac agcgagtctc cattgcacgc gcggtagcca aaaatcctaa aattctcctt
    31261 tgtgatgaac cgactggagc cttggattat cagacgggca agcaggtttt gaaaattctc
    31321 caagacatgt ctcgtcaaaa gggagcgacg gtgatcatcg tgactcataa tggagctttg
    31381 gcgcccattg ctgatcgcgt gattcatatg cacgatgcca gtgtcaagga tgtggtgctc
    31441 aaccagcatc ctcaggatat tgacagtttg gagtactagc atgatcaagc gaaaaactta
    31501 ttggaaggac ttaattcagt ccttcacaga ctccaagggg cgttttttat ccatcttgat
    31561 cctgatgatg ttgggatctc tagccttagt aggcctcaaa gtaaccagtc ccaacatgga
    31621 ggcgacagct aatgcttatt taacaactgc tcaaaccttg gatttggcag tcatgtctaa
    31681 ctatggcttg gatcaagcag accaagaaga actaaaacag acggagggcg cagaggtcga
    31741 gtttggctat ttgacagatg tgactatgga taatgggcag gatgccattc ggctgtactc
    31801 caaaccagag cgaatttcaa cctttcagct aagaaaggga cgacttcctc agtcagacag
    31861 ggaaatcgct ttggccactc atttgcaagg ccaatacagc gtgggacagg agattagttt
    31921 taaagaaaaa gaagagggtc attcctcttt aaaagaccat acttatacca ttactggttt
    31981 tgtggattcg gctgaaatcc tctcccagcg agatatgggc tacgcaggaa gtggaagtgg
    32041 gactctgaca gcctatgggg tgattttacc tagtcaattt gatcagaaag tctacaatat
    32101 agctcgtttg aaatatcaag atttagcagg tttaaatgcc ttttcatcag cttatgaaga
    32161 aaaatccaag caacatcagg aagaccttga acaaacttta tcagataatg gcaaggtacg
    32221 tctgcaactt ttgaaaaaag aaggacaaga gtctctagac aaggggcaag agactcttga
    32281 caaggctcag actaatttgc aggaaggcaa gcgtcgttta gcagctgctc aagctcgtat
    32341 acaggctcaa gaaagtcaac tagccttgtt tcctcaagct cagagagagc aggctagtgc
    32401 tcaacttacc caagccaagc aggaactggg caaggaagag gacaaactaa agcaagctga
    32461 acaaaatcta gcccaagaaa aggaaaaatt agaaaaacat cagcaagtct tggatgattt
    32521 ggcggagcca aggtatcagg tttataatcg tcagaccatg ccaggtggtc agggctatct
    32581 tatgtatagc aatgcttcat ccagtattcg agcagtgggc aatatctttc ctgtggtact
    32641 ttatgccgta gcagccatgg tgacctttac gaccatgact cgctttgtag acgaagagcg
    32701 aactcatgca gggattttta aggccttggg ttatcgtagt aaggatatta tcgccaagtt
    32761 tctcctttat ggactagtag ctgggactgt cggaacggct ctaggtagta tacttggtca
    32821 ttatttgcta gccagtgtaa tttcaagtgt cattacaaaa ggcatggtgg tgggagaaac
    32881 ccagattcag ttctattgga cctatagctt actagctctt gtcttgagct ggttggcgag
    32941 tgtgttacca gcctatctgg tggcttggag ggaacttcat gacgaagcag cccagcttct
    33001 acttcctaaa cctcctgtca aaggagctaa aatcttattg gagcgtatcg gttttatctg
    33061 gcgtcgtctc agttttactc ataaggtaac agcccgcaac atctttcgtt ataagcagag
    33121 aatgttgatg acaatctttg gtgtggcagg ttctgtagct ctgctctttg caggtttggg
    33181 aatccaatct tctgtagcag gagttccgtc taaacagttt caacaaatcc aacagtatca
    33241 gatgcttgtc tctgaaaatc ctagtgcgac caatcaggac aaggtagagc tagcagaagt
    33301 gttgaaaggg caggagatac tagcctacca gaaaatctat tctaaaacgc tagacaagga
    33361 tttcaagggc agggctggtc ttcaaaacat tactcttatg atgatagaga aggaagattt
    33421 gactcccttt atccatcttc aacatcatca gcaggagctg acattaaaag atggcatcgt
    33481 tattacagct aaactcgccc agctggcagg tgtcaaggtt gggcagactt tagaaattga
    33541 aggtaaggaa ctaaaggtcg ctgctattac tgagaactac gttggtcact ttatttatat
    33601 gagtcaggct agctatgagc aactttacgg acagctaccc caagccaaca cttatctggt
    33661 ctcattaagg gataccagtg caactagtat cgaaagtcag gcgggcttgc ttatgaatca
    33721 atctgcggtg tccagtgttg tccaaaatgc ttcagccatt cgactcttcg actctatcgc
    33781 tagctcactc aatcagacca tgaccatctt ggtcatcgta tcggttctat tagctattgt
    33841 catcctttac aatctgacca atatcaacgt agctgagaga atccgtgaac tctccactat
    33901 caaggttctc ggttttcata ataatgaagt caccctctac atttaccgtg agacgattgt
    33961 gctgtccctt gtgggaatcg tacttggtct ggtagctggt ttctatttac accaattttt
    34021 gattcaaatg atttcgcctg cgactattct cttttatccg caggtaggct gggaagtcta
    34081 tgtaatccca gtggcagcag taagcatcat tttgaccttg cttggtttct tcgtcaatta
    34141 ttatctgaga aaggttgaca tgttagaagc cctgaaatct gtagagtaag gtagttattt
    34201 ttagctgatt gaacttctat ttactaatat tcaaaaatcc tccgtttcaa agagcaggga
    34261 actctttgtg acagaggatt ttttctatag ggctttagca gctgcaattg cggcttcgaa
    34321 gtttggctca gaattgatat tatccacgta ttcaacgtag cgaatcgtat tgtcagtatc
    34381 gaggacaaag actgcgcgtg ctaataggtg ccattcgttg atcaagaggg cataatcgcg
    34441 tccgaaagaa tggtcaaagt agtctgaaag cataatggca ttgtcaaggc cttcagcacc
    34501 gcaccaacgt ttttgagcaa aaggtaggtc cattgaaaca gtcaatacga ccgtgttgtc
    34561 cagtccagcc aattcttcat taaaacgacg tgtttgagtt gagcagatgc ctgtatcgat
    34621 agaaggaacg acactcaaga cttttttctt gccatcaaaa tcagccagag attttttaga
    34681 aagatctgtt gtagtaagag aaaaatcaag cgccttgtcg ccgacttgta gttgtttacc
    34741 tgtaaagctc acaggatttc cgagaaaagt taccatagga tactccaatc ttttttcttc
    34801 cattgtatct gaaacagtca gaattttcca atgatttgac cggaaatgtg tgcatagaaa
    34861 aaacgccagc tcacatgaga atgacgtttt tcagaggctt attttgccaa tccttcagca
    34921 atcttgtcaa ggttgtattt catcatgctg tagtagctgt cgccttcttt accttgttct
    34981 gcgatagagt cagtaaagat ttgtgcgtag attgggatgt ttgtgtcttg agaaacagtt
    35041 ttcattggac ggtcatccac acttgattct acaaagagtg atggaacttt tgtttggcga
    35101 agtttttcaa ccaaggtctt gatttgttca ggagttcctt cttcttcagt attgatttcc
    35161 cagatgtagg cacttgggac accataggct ttagagaagt atttgaatgc tccttcgctg
    35221 gttacaatga gtttcttttc agcagggatc ttattaaatt tatccttact ttctttatca
    35281 agtttgtcta acttatcagt atattctttg agattttttt catagaattc tttattgtta
    35341 gggtctttgg cgctcaattg tttggcgata tttttagcaa aaataatacc gttttcaagg
    35401 ttaagccaag cgtgtgggtc ttcttttcct ttttcatttt gaccttcaag gtagataaca
    35461 tcaacgccgt cgctgactgc gaagtagtct ttgttttcag ttttcttggc attttctacc
    35521 aattttgtaa accaagcatt gccacctgtt tcaaggttga taccgttata gaaaatcaaa
    35581 tcagcctcag aagttttctt aacgtcttca ggaagtggtt cgtattcgtg tgggtcttgc
    35641 ccaatcggaa cgatactatg aaggtcaatt ttgtcaccag caatattttt agtaatatca
    35701 gcgatgattg agtttgtagc aacaactttt agtttttgac cagaagttgt atcttttttt
    35761 ccgctagcac atgctacaag aatgattgca gaaagaaaga gaacgagtaa tgtacctaat
    35821 tttttcatta gatcctccaa tttattaggg ctttgcccct tattttaaca aatgtttatt
    35881 tttcagtttc aaatatcgtt gtttgggagc gataaagaag ctaatgagaa agaaactagc
    35941 agctgtaagc acgatactag aacctgccgc aacattaaaa ctatagccaa taaagagtcc
    36001 caaaactgaa gcagtagctc cgaaggttga ggaaaggaaa atcatgcttt tcagactatt
    36061 agcatacaga taagcagttg cagctggggt aatcagcatg gctacaatca ggatagttcc
    36121 gacactttgc atggctgtca cagacacgag agtcaggagt accatgagaa ggtagtgata
    36181 gaaattgaca ggcattccca tggctttagc caagagttca tcaaaggaag ttatcaagag
    36241 ttgcttgaag aaaatccaga ttaacaagag gatggctgcc cccacaccca tagtaataaa
    36301 catatccgta tcttggacgg ccagaatatt accaaaaagg atatggaaaa ggtcagttga
    36361 acttttagcg acaccaatca agatgatacc gagggctaag aaagaagaaa aggtaatgcc
    36421 gatggcggta tcgcttttga taatcgagtt tcctttgatg taggtaatga tgatggcagc
    36481 tagcaatcca aagacaatgg ctccgataaa gaagtcaagg cccaagatga aggagagggc
    36541 tacacctggt aagacagcat gtgaaatggc atctcccatg agtgacatcc cgcgtagaat
    36601 aatgaaacat cccacggctc cagctacaat cccgacgaca atagctgtta tcaaggcatt
    36661 ttgtaggaaa tggaattttt gcaatccatc gataaattct gcaatcatag gtcacctcca
    36721 ttgaaaaaga gttgattacc gtaagcttct tttagattgg tttcggtaaa agtttctttt
    36781 gttggaccaa aggcaatcac ttctcgattg acaagtaaga cttgatcgaa gtagtgggga
    36841 atcttgctga ggtcgtggtg aacgatgaga accgtcttcc cagctttttt caaatctctc
    36901 agcgtattca tgatgatttc ctcactgaca gagtcaatcc cagcaaaggg ttcatccaag
    36961 aggatatagt cggcttcctg caccaaacat ctggcaatca agacccgctg gaattgacct
    37021 ccagacagtt gactaatttg acgttcagcg tagtcagcta ggccgacgat ttcaagggcc
    37081 tcttgcactt tcttccaatg tttagccttt aaacttcgaa agagaggaat agagggaaat
    37141 agtcctaacg agacgcattc cttgaccttg atgggaaagt tgtagtcgat attgattttt
    37201 tgttcgacat aggcaattcg gtgtaaggat tttttaactt ccttgtcatc gagaaatgcc
    37261 tgaccttgat gtgggataat tcccagcata ccttttaata gtgttgattt cccagcgccg
    37321 tttggaccaa tgatgccggt aattgttggt ccatggagca ctagtgaaat atccttaagt
    37381 gccaacgttt ctttgtagga gacactgagg ttttcgatac gtatcataaa cttgtattcc
    37441 tcctgtctct taatatacat taaaaaaaaa attaagtcaa gttaattttt gaaaaaatta
    37501 aaataataac tgaaaaatag attctaaaga taactttcag gataaatttc taaattataa
    37561 aacgcatagt atcaagtgta aaaaacttgg aattatgcgt tttatcatgg aaagattttt
    37621 tataatagct aaaaaataat agttaaatgg ttattaattg cattccctag tgatttttgt
    37681 taagataaat gcaaatacaa atgaaagcga gaacaagatg acacgttatc aagatgattt
    37741 ttatgatgct atcaatggag aatggcaaca gacagctgaa atcccagcag ataagtctca
    37801 aacaggaggt tttgttgatt tagaccagga aattgaagac ctgatgctgg cgacaacaga
    37861 caagtggtta gcaggtgaag aagtgcctga ggatgctatc ttggaaaact ttgtcaaata
    37921 ccaccgccta gttcgtgatt ttgacaagag agaagctgac ggtatcacac ctgtcttacc
    37981 actccttaaa gaattccaag aattggaaac ttttgcggat tttacagcta aactagcaga
    38041 gtttgagctt gcaggaaaac caaacttcct tccttttggt gtatcgccag actttatgga
    38101 tgctagaatc aatgttctat gggctagcgc tccaagcaca atcttgccag atacgaccta
    38161 ctatgcagaa gaacatcctc agcgcgaaga gctcttgact ctttggaaag aaagcagcgc
    38221 aaatctcctc aaggcttatg atttctctga tgaagaaatt gaagacttgc tagaaaaaag
    38281 acttgaattg gaccgccgag ttgcggcagt ggtgctctct aatgaagaaa gttcagaata
    38341 tgctaaactc tatcatccat attcttacga agatttcaag aaattcgcgc ctgccctacc
    38401 tttggatgac ttcttcaaag cagttattgg gcaattacca gacaaggtta ttgtagacga
    38461 ggaacgtttc tggcaagcag cagagcaatt ttacagtgag gaagcctggt ctctccttaa
    38521 agcaaccttg attttgagtg ttgtcaatct ttcaaccagc tatttaacag aggatatccg
    38581 tgttttgtct ggtgcctaca gccgtgccct ttctggagtt ccagaggcaa aagataaggt
    38641 caaagcagct tatcatctag cacaggaacc tttcaagcaa gccctggggc tttggtacgc
    38701 ccgtgagaag ttctctccag aagccaaggc ggatgtggag aaaaaagtgg caaccatgat
    38761 tgatgtctat aaggagcgtc tgcttaagaa tgactggctc actccagaaa cctgtaaaca
    38821 ggctatcgtg aagctcaatg tgatcaaacc ttatattggc tatccagaag aattgcctgc
    38881 acgttacaag gataaggtag tgaatgaaac tgccagtctt tttgagaatg ctctagcctt
    38941 tgcgcgtgtg gaaatcaagc acagttggag taagtggaac cagcctgtag actataagga
    39001 atggggcatg cctgctcata tggtcaatgc ctactacaat cctcagaaga acctgattgt
    39061 ctttccagcg gccattttac aggcgccttt ctatgacttg catcagtcat cttctgctaa
    39121 ctacggtggt attggggcag tgattgccca tgaaatttcc cacgcctttg atactaacgg
    39181 ggcttccttt gacgaaaatg gtagcctcaa ggattggtgg acagagagcg actatgctgc
    39241 cttcaaggag aaaacacaaa aagtcattga ccaatttgat ggacaggatt cttatggagc
    39301 aaccattaac ggtaaattga ctgtatcaga aaacgtggct gacttgggag gaatcgcagc
    39361 agcgcttgaa gcagctaaga gagaagcaga cttctcagca gaagagttct tctacaactt
    39421 cggtcgcatc tggcgcatga aaggtcgacc agaatttatg aaacttttgg ctagcgtcga
    39481 tgtgcacgca ccagccaaac tccgtgtcaa tgtgcaagta ccaaacttcg acgatttctt
    39541 tacaacctat gatgtcaaag aaggagacgg aatgtggcgt tcaccagagg agcgcgtgat
    39601 tatttggtaa tacaaaaaat ctagtcatca gaaaaaaggc atccaatcac gtgtgaaaac
    39661 cttgatagga tgccttttgt aatagaaaga tttgctggat agtttactta aatttcgatt
    39721 gtcatcatct tgctagaaaa agggattgaa ggccttttcg tgagcgatag tagtagctgg
    39781 accatgtcct ggatagacat cgtagtttgg tagggtgaag agttgggtct ggatactatg
    39841 aaggagttgc tccatgctac cagtcggaag gtcggtccgt ccgatagttt cgcggaatag
    39901 agcatctccc gtcaagacta ggtgagcatc aggaaagact agggaaacac caccgataga
    39961 gtgccctggg gtcggtagaa ccttaaaacg aaattcctct agttggtatt cttcgtgaaa
    40021 gacaaaggtg tgttctgcag gttttgtgac cacatctgcc atatcatcgt ggcgagggag
    40081 accggagaga ttatcgacag gagtgtagag ccagctggct tcgctctctg cgatatagac
    40141 aggaggattg ccaaacgtct cgcgaaccaa gtccagactc atgatatggt cataatgggc
    40201 gtgggtcaag agaatagcac agatcggttt gttgatcttc tcgattgtct gacgaatggc
    40261 ttcccaatga ctaccaggat cgacgacgat gaggtgcttt tcgccttcta gataataggt
    40321 attttcatag gcaacaggat tcacggtttt atggattttc atactagctc caatctcaaa
    40381 gaatgtacta atactcttcg aaaatctctt caaactgcgt caactttatc tgcaacctca
    40441 aagcagtgct ttgaacagcc tgcggctagc tttctagttt gctctttgat tttcattgag
    40501 tataaattaa gtatagcaca gttagggaga ataggtaagg atttaaaatg aacttaaaaa
    40561 ccagcatgac tagatgaaga caggctggtt atcaatttat caatattgga aaggtgtcaa
    40621 ttgcccttca taggttgcat aaactccgtc attagcttgt ttgatagacg tgatgtttag
    40681 agtgctaccg tagttggctt ctcgtttgtc gctatattca ctataagtta tcctactggg
    40741 caggttctgg tcgttagcat agtattgaac gactgttttt tatagctttg ctggctgaat
    40801 aggaacaggc agcaaactcc taacattagg agagcaaaga tagaaatagc agtttttttc
    40861 ataggtattc tccttataaa ctaaaggata gaagaaagta tcttgaggat ttttatactc
    40921 ttcgaaaatc tcttcaaacc gcgtcaacgt cgccttgccg tatatatgtg actgactttg
    40981 tcagtcttat ctacaacctc aaagcagtgc tttgagcaac ctgcggctag tttcctagtt
    41041 tgctctttga ttttcattga gtattaattc caaaatccag tcaaggtacc agtgtatgtg
    41101 atacgagttc caccgtttat ctttcgtatc ttcaatggaa ttggggaaat cagaaagtct
    41161 ttgggttaca atatggtttc cgttcttcta tctctccttc tatcacctaa gtttaaaatc
    41221 taacttcgta gtatattatg ggccaataat tcagaattat caagcaattt tgaattattt
    41281 ttttcttatt ctgttccaat ctagttttca tattcttaaa aaagtgataa aatggtagga
    41341 agaattggag agtagagatg ccgaaagaag tgaatttaac aggcgaagaa gttgtcgctt
    41401 taaccaaaga atatttaacg gaagaggatg ttcattttgt ccataaggcc ttggtctatg
    41461 ctgttgaatg ccacagtggt caatatcgca aatcaggcga gccttatatc attcacccta
    41521 tccaagtggc aggtatttta gctaagctaa agctggatgc tgtaacagta gcttgtggat
    41581 tcttgcatga tgtggtggaa gatacagatg cgaccttgga cgatttggaa agagagtttg
    41641 gtcctgatgt gcggatgatt gttgacggag ttaccaagct tggcaaggtc gagtacaaat
    41701 cgatcgagga gcaattagcg gaaaatcatc gcaagatgct catggccatg tctgaggaca
    41761 tccgcgttat tttggtcaaa ctgtctgacc gcttgcacaa tatgcggacc ctgaaacatc
    41821 ttcgaaaaga caagcaggag cgtatttcca aagaaaccat ggaaatctat gccccgcttg
    41881 cccatcgttt ggggatttcc agtgtcaaat gggaattaga agacttgtct ttccgttatc
    41941 tcaatccaac ggagttttac aagattaccc atatgatgaa ggaaaagcgc agggagcgtg
    42001 aggccttggt ggatgaggta gtcacaaaat tagaggagta tacgacagaa cgtcacttga
    42061 aagggaagat ttatggtcgt cccaagcata tttactcaat tttccgcaaa atgcaggaca
    42121 agagaaaacg gtttgaggaa atctatgatc tgattgctat tcgttgtatt ttagataccc
    42181 aaagtgatgt ttatgccatg cttggttacg tgcatgaatt ttggaaaccg atgccaggtc
    42241 gcttcaaaga ctatatcgcc aaccgcaagg ccaatggtta tcagtctatc catacgactg
    42301 tttatggacc aaaagggccg attgaattcc agattcgaac caaggaaatg cacgaggtgg
    42361 ctgagtacgg ggttgcggct cactgggctt ataagaaagg tataaagggg caagttaaca
    42421 gcaaggaatc agctattgga atgaactgga tcaaggagat gatggagctc caagaccagg
    42481 ctgatgatgc taaggaattt gtggactctg ttaaggaaaa ctatttggct gaggagattt
    42541 acgtttttac cccagatgga gctgtccgtt cccttcccaa agattcagga ccgattgatt
    42601 ttgcctacga aatccatacc aaggtcggtg aaaaagcaac tggtgccaag gtcaatggcc
    42661 gcatggttcc actgacaacc aagttaaaga caggggatca ggttgaaatt atcgccaacc
    42721 cgaactcctt tggacctagc cgtgactggc tcaatatggt caagactagc aaggcgcgca
    42781 ataagattcg ccagttcttt aaaaaccaag ataaggaatt gtctgtcaac aagggtcgtg
    42841 agatgctgat ggctcagttc caagaaaatg gctatgtggc aaataaattt atggacaagc
    42901 gccacatgga tcaagttctg caaaagacca gttacaagac agaagactcc ctctttgcgg
    42961 ccattggttt tggggaaatc ggtgcgatta ccgtctttaa ccgtctgact gaaaaggaac
    43021 gccgtgagga agagcgtgcc aaggccaaag ctgaggcaga ggagcttgtc aaaggtggcg
    43081 aggtcaaggt tgaaaataaa gaaaccctca aggtcaagca tgagggggga gtggttattg
    43141 aaggtgcttc tggtctccta gtgcggattg ctaagtgttg taaccccgtg cctggtgacg
    43201 atattgttgg ctacattacc aagggtcgtg gtgtggctat tcaccgtgtg gactgtatga
    43261 acctgcgtgc ccaagaaaac tacgagcaac gtctccttga tgtggaatgg gaagaccagt
    43321 actctagctc aaataaggag tatatggccc atatcgatat ctacggtctc aaccgtacag
    43381 gactgttgaa cgatgtactg caagttcttt caaatacaac caagaatatt tcaacggtca
    43441 atgcccaacc aaccaaggat atgaagtttg ctaatatcca tgtgtccttc ggtattgcca
    43501 acctctctac actgaccacg gttgtcgata aaattaagag tgtgccagaa gtttactctg
    43561 tcaaacggac caacggctag ttgtcctagc tcttactaga aaggctatta tgaaaatcat
    43621 tatccaacgg gttaaaaaag cccaagtgag tatagaaggc cagattcagg gaaaaatcaa
    43681 tcagggattt ttattgctgg ttggtgttgg accagaggac caagaggaag atttggacta
    43741 tgctgtgaga aaactggtca atatgcggat tttttcagac gcagaaggca agatgaacct
    43801 gtctgtcaaa gatattgaag gagaaatcct ctctatttct cagtttaccc tctttgcgga
    43861 tactaagaaa ggcaatcgtc cagcctttac aggggcagct aaacctgata tggcatcaga
    43921 cttctatgat gctttcaatc aaaaattagc gcaagaagtg cccgttcaga caggcatctt
    43981 tggagcagat atgcaggttg agctggttaa taacggacct gttaccatta tcctagatac
    44041 taaaaagaga tgagaaagac caagcccagt cggcttggtc tttctcatct atcataaaat
    44101 actccaaaaa gaaatcggtt cttgatatgc ttgggggaag tctcttttca ggctttggca
    44161 gatgcgatag gaagggatga gatgtcctag gatgaggaga gttccctgaa ggaaaagtgg
    44221 aatatcactt aaagacacca aggagagaat catcaggcta tcccatagga gaatttgtaa
    44281 agcaaaacgc cagaatctcg gtctaatctg ggaatagagt taactaaagt ggtcacaaag
    44341 ttggtttgaa agataggtca atagcacagg atgaaagaaa atgagccaac cgctataaat
    44401 caaaatccag tcccaagtaa gctccctttt aaatgtcaaa aatgccagca tgattccatc
    44461 aatgacaagg agttgaatgg ttttgatgaa tatgattttt ttcatgctaa aacctccttt
    44521 tccttagaga cactcccata aagagatgtg tttgtcgtaa aagtctggat agttttctcc
    44581 taggtagtca gctgtcatat aataaaaagt agaatggcga gcagtgatga ttggcataag
    44641 agatgaaaaa cgctgagaac taatgaaggc taagagaaca aaaaatagaa aatcaatggt
    44701 gagaatccct aaatagtaga agcgaatctt tttattgatt tgaggataaa tctcagcgaa
    44761 ttgatgtttg agtcggacga ccaagagaaa tagcaggagt ccttgatcaa ggaagaaaat
    44821 taaaccagag agcaagagcc actcaaaaga tgtctcgagt ctagtgataa aaaatgcaaa
    44881 tagtagcaaa tcaataactg caattgctat aaaatggatt ctatagagtt ttttcatgac
    44941 aagaccttcc tcttttatct aacttcattc tactccaaaa gaatgggagt tacaactaaa
    45001 atgataaaaa tagcagaggg gagattctct taagttggct agtattcttt atttgagttt
    45061 ccttctatta tctaacttct tcatcattcc agacaaataa agctccgatt gcattgagga
    45121 tataaaagat gtatttaccg atattggcga agtttccttg aataccagct tttgtcagct
    45181 gaacgaaatt gtaaatcaac caaaagcccc actgagttgt tagtttcaat gcattcaaag
    45241 cattggcaat gagggacagt gcaaaggcaa tagttgttac gtaggcaagg agattcatct
    45301 tgcccccata tccgatatag ttggtcacaa aggcaaagag gaaggcgatg atggaaatga
    45361 tgatgggcgc caattttacc tgtttttggc tcatttggtt gggtctgcct tcttgcgaag
    45421 ctttccattt ctttatagca aaggtataaa tgaggaaggt gacgggatag gtaatgatgg
    45481 ccgccttatt tccaaggata taatcaatag caccggacaa aatggtatta acaataccaa
    45541 agtaatttcc ccatttgctt aatttccccg tgaaacgagt ggacaacatg gaaatcccaa
    45601 cgttagttac ggaaatcaat ccaaagggta caagagctgt ccatagtccc cagtctacaa
    45661 atttatggag gcgtgagttg agataaccag atgcaatcgc aatcccaacg accaaagcaa
    45721 ccccgaagag gtcaaactat ttagatgtag caaaaatttt tagtgatttt ttcataggtt
    45781 aaactacctt tctttttttc aaatattctc ccattttttt caaatattct cacaccaaat
    45841 gaaagtaaaa taaaatgata gaaataaaac cctgaaaata aaactttcag ggttggtagg
    45901 ggacttgaga aattagttga ttttctcgac atagagttgt tttgcaatgt ccatattcac
    45961 ttgtaaatcc tcgtcgttac tgaggatagt gaaggtattg ctgaagccat caaactgctt
    46021 gacttggagc tggtcaccga tgtgaagtga gtgcttgtcc agataatgga gaatgtcaaa
    46081 actatcgtgc acccgagtca ggcggtaggc gccagcttcc ttgatatcag ctagtgggag
    46141 gttattgatt tcaacgagga gttctccctt ggcaggaata gttcctccgt gggggcaggt
    46201 tttagggaaa cctagcagtt tatctagtct ttccacgaac aggtcagaga cagtgtgttc
    46261 caagacctca gcttcctcgt gaatctggtc acttgtatag tctaaatgat gaactagaaa
    46321 aacttcaatc aagcggtgct tacgatagag ctcagagacc agtttgagac cgaggtcagt
    46381 cagtagatag ccacattcct tgtcctttag gatgagattt tcacttttca ttcgtttgat
    46441 catttcagtt acggcagggg gagagacttg catgcgagcc gcaatttcct tgttggtaat
    46501 cttatgcagg tctatgccaa tttcataaat acattttaga tagtcttctt tgtttggggt
    46561 cattcgtttc ctcttgtcta atatctttat ctagtatatc aaaaaaagct agatttctct
    46621 agctgtgact ttttatgtta tacttattgc aagagaaaaa acgaggagat ggatatgacg
    46681 aaaatagctc ttctttcaga tattcatgga aataccaccg ccttggaggc tgttttggca
    46741 gatgctcggc agataggagt ggatgaatac tggcttttgg gagatattct catgccaggg
    46801 acagggcgta gaaggatttt ggacttgttg gatcaactac cgattacggc tagagttttg
    46861 ggaaactggg aagacagtct ttggcatggt gtccgtaagg aattggatag tactcgcccc
    46921 agtcaacgct atctcttgcg ccagtgccag tatgttttag aggaaatttc cctagaagaa
    46981 attgaagtgc tccacaatca acctcttcaa attcatcgtc agtttgggga tttgacggtg
    47041 ggaattagtc atcatctgcc tgataagaac tgggggcgag agttgattca tactggcaaa
    47101 caagaggatt ttgaccgctt ggtgactcat cctccctgtg atattgctgt ttatggacat
    47161 attcaccagc agttgcttcg ttacgggact ggtgggcaat tgattgtcaa tccgggttcg
    47221 attggccaac ctttcttttt ggacgctcag ctacggaagg acttgcgggc ccagtatatg
    47281 attttggagt ttgatgacaa gggcctggta gatatggact tccgacgggt agactacgat
    47341 gtggcagctg aattgcagct ggctaaagac ctgagacttc cctattttga ggtttactat
    47401 gaaagtctgg tcaatgggat ccaccatact catcatcagg aatttttgag agaattggct
    47461 cagaaagagg gctgcgaccg ggagttagac gactggttga aaagtggtaa cgattgacat
    47521 tacaactaaa aagggtataa taatagaaaa agaagagtag aggcagggta gcctcgtaaa
    47581 aaggagaaga ggatgcaaat tccaagtaga tttaccattg cgactcatat gctgataatc
    47641 attgccctcg aggggaagga aagcaaggtg accagtgatt ttctggctgc tagtgtcggg
    47701 gtcaatcctg tcattatcag aaagatcttg tcccagttga agaaggcaga gctgatttca
    47761 gtagcgcgtg gaacgggcgg aacagagatt gtcaaggacc ttaaggatat tagtctttta
    47821 gatgtttatc aggcggtcga atgtcttggt aagacaggtc aactcttcag tttccatgac
    47881 aatccgaatc caaattgccc tgtaggagct catattcatg atgttttgga tcaaaaattg
    47941 gagagaattc agttgactat ggaggcagaa cttggtcaaa ccagtctaga aaaagtcgtg
    48001 gccgatgcag agagtcagat gaaggattaa gagggataaa tgccctcttt tttctttgga
    48061 taattatgat aaaatgtagc tattaaagga gtaagaaatg tatctcgtta taggaattgt
    48121 attagccttt atagtgtcat tttggaagga taatagaagt ttgtggaatc cagtattatt
    48181 tttattatcc ctcatttcaa gttattttta tctatcctac cttttttata aaaatggata
    48241 cgagaatgtt cagttagctt tttatgtatt tgcctttgtc ttacttcctt ttttgctttt
    48301 tctaagtggc atctttttaa tctataatgg ggtcattttg ttgaagcgag agggacgttc
    48361 caagccccat tatctctcaa tgctctttga tttttattga ctattagatt ctatttaaaa
    48421 agacttagaa tgcacatgaa agtatgtatt ctaggtcttt tgttttgtat acatttaatt
    48481 ttcaagagta ttatctattt ttccatgcct ggtaacgagt atcaatcaat aactgggtaa
    48541 ggcgacccaa ggtttctctt tcttctggag tgagggattg agcttggaca aagagatgat
    48601 gaatgtattc aagcgccttt aaggaagcca agtcattgat agagctaata ccagcctcaa
    48661 gaatagtgcc aaagaagagg tcgaagtaga gctgaagttc ttcgtcaggg actgtggcca
    48721 cccattcttt aaaggttgtg tctacttgct ggctatcact gttggtctta tccagttgga
    48781 cgaagtgctt gtcctcaatc tgccaactaa aggtatcgtg ctgggcgatg ccacccaggg
    48841 cagtactctg aacgatgatt tggtgagcag gaatttccag catcataccg ataatggaac
    48901 cttgtggaat gaatatcttg cttctatcca ttatcctttg ataacccgca gtctgtgtca
    48961 attcttgatg gagaccaggt gcatcaaatg tataaactgc tgtgatctga ttttgcaaac
    49021 tttgctcaat ttggctagca gcatagatag cgagatttcc tcccttggaa tgcccagcta
    49081 gaataacctt ttgcttagga tgatgggcaa aaaagttctt taaatagcga agggcgtgct
    49141 tttgagcagg aatttccttc atataggtca ggtggaaatc ttccttccag ccaatgatac
    49201 tgtcatctgt cccacgaaag acaatcagat aggtatcgag gctgacacga taagtcatag
    49261 ccgcaaattg cttttgcagt tcagggtcga tgtcgttgat aaaatgggag agtttgcaat
    49321 ttttgaagcg cttgtgttga gccaattcat ctaataattg aaggcgattt ttgctagtaa
    49381 gcatggtggg atctcttgga acctgaggtg ctagatctaa aagacgttga ggaagtgtgg
    49441 agaccagatt atcaaaggag aggtaggtga tttctattaa ggttagaatg tctaactcat
    49501 tcaagggaag gtcgtaataa gaatcatatg cgacatcttt cagatagtca aaaatattgg
    49561 ccataagagc tcctttcttt ttatttatct tagcaaattt ccctcaaatt agctagtagc
    49621 attgcctgtt tgtactggct aaaaacaggc tatttcaaat tcagtttcag accatctggc
    49681 atggaaaaat ctgttataat aatggaaaag gagaagcgca tgcacaagat tttattagtg
    49741 gaagatgatc aggtcattcg tcaacaggtc gggaaaatgc tctctgaatg gggatttgaa
    49801 gtggtcctgg tagaagactt tatggaagtt ttgagtctat ttgttcagtc ggaacctcat
    49861 ctggtcctca tggatattgg tttgcccttg tttaatggtt atcactggtg tcaggaaatc
    49921 cgcaagattt ccaaggtacc tatcatgttt ctttcttcga gagaccaggc tatggatatt
    49981 gtcatggcaa tcaatatggg ggcggatgac tttgtgacca agccttttga ccagcaggtt
    50041 cttttagcta aggttcaggg cttgttgcgt cgttcctatg agtttgggcg tgatgagagt
    50101 ttgctggaat atgctggtgt tatcctcaat accaaatcca tggatttaca ttatcaaggg
    50161 caagtcttga atttgaccaa gaatgaattc cagattttac gcgtgttatt tgagcatgca
    50221 ggcaacatcg tagcacgtga cgacctgatg cgggaacttt ggaacagtga ctttttcatt
    50281 gatgataata ccctctctgt caatgtggct cgtttgcgta aaaagttgga ggagcaggga
    50341 ttggtaggat ttatcgagac caagaaagga atagggtacg gattgaagca tgcttgattg
    50401 gaaacaattt tttctagcct atctgcgctc ccgtagtcgt ctttttatct atctgctttc
    50461 tttggcattt ctggtcttac tctttcagtt tttatttgcc agtctaggaa tttacttcct
    50521 ctactttttc ttcttgtgtt gctttgtaac catcttattt ttcacttggg atatattggt
    50581 ggaaacgcag gtctatcgcc aggaacttct ctatggagag agggaagcca agtctccttt
    50641 ggaaatagct ttagcagaaa aattagaagc gcgtgagatg gaactctatc agcagaggtc
    50701 aaaagcagaa agaaaactga cggatttgct ggattactat accttgtggg tccatcagat
    50761 aaagaccccc attgcagcca gtcaactctt agttgcagaa gtggtcgacc gccaactgaa
    50821 gcagcaacta gaacaggaaa ttttcaaaat cgactcctat accaacctag ttttacagta
    50881 cctgcgttta gaaagtttcc atgatgattt ggtcttaaag caggttcaaa ttgaggactt
    50941 ggtcaaggaa ataattcgta aatatgctct tgtctttatt caaaaaggct taaatgtcaa
    51001 tctacatgac cttgataaag aaatcgtgac ggataaaaag tggctgctag tggttattga
    51061 gcaaatcatc tcaaacagtc tcaagtacac caaggaaggt ggtctggaga tttatatgga
    51121 tgaccaagag ctttgtatca aagatacggg aatcgggata aaaaacagtg atgtcctccg
    51181 agtatttgaa cgtggctttt caggatacaa tggccgtttg acccagcagt cctctggact
    51241 tggcctttat ctatctaaga aaatttctga agaactgggg caccagattc gtatcgagtc
    51301 tgaggtcgga aaaggaacga cagtgcggat tcagtttgct caagtgaact tagtccttga
    51361 gtaaaaatag atgagaaaaa gcctccagat tggaggcttt tatgctagac tcttatttct
    51421 caacgcgtga tttgttggcg atatcagcta ggatagcttg aacaaaatta tcaactgaga
    51481 cagtttgtgt ttctttttgg ccgtagcgac gaacgttgac tgtttcgtct tccatttctt
    51541 tgtctccaac aattaattgg taaggaatct tgctggtttg tgaagcacga atcttgaact
    51601 gcattttttc attgcgctca tctacgtctg cacggacacc gcggtcacgg agtttcttgg
    51661 ccacttccca agcgtagtcc acgtgttttt cgttagatac tgggatgagg gttacttggt
    51721 gtggtgccag ccatgttggg aaggccccct tgtagttctc aatcaagata gctgtgaagc
    51781 gttccatagt tgagataacc ccacggtgga tcatgactgg acggtgatct tcgccatcag
    51841 ctccgatgta tttgaggtcg aagcgttctg gcaacaagaa atcaagttgg atagtagaaa
    51901 gggtttcttc ttttccaagg gcagttttaa tctggatatc caattttggt ccgtagaagg
    51961 ctgcttcacc ttcggcttca aagtagttca cgcccatttc atcaagagct gcacgaagca
    52021 tggtttgggc attttcccac atctcatcgt tatcaaagta cttatgagta tcttgagggt
    52081 cacgaagaga gaggcggaag cggtagtcag tcaagttgaa gtcttcataa acatcgataa
    52141 tcaactgaag ggcacgttgg aattcttctt ggatttgttc tggagtaacg aataggtgac
    52201 cgtcgttgag tgacatttca cgtacacgtt gaaggccagt gagggcacca gatttttcgt
    52261 aacggtgcat cataccgatt tcagcgatac ggattggcaa ttcacggtaa gagtgaacat
    52321 ggtgtttgaa aacttggatg tggtgcggac agttcattgg acgaaggaca aattcttccc
    52381 cgtcacccat gtccatggtt gggaacatgt cttcttggta atgatcccag tgaccagaag
    52441 tcttgtaaag ctcaacagaa gcaagtggtg gagtgtagac gtgttggtag ccagaagcca
    52501 actctttgtt tacgatgtag cgttccaatt cacgacggat agtcgcacca tttggcaacc
    52561 agaatggcaa accttgtccc acttcttgtg aaattataaa gaggtcaagc tctttaccaa
    52621 gtttacggtg gtcacgttcc ttagcttctt cacgcatttg aaggtagttt ttcaagtctt
    52681 tcttgtcaaa ccaagctgta ccgtagatac gttgcatcat agcgttgtcg ctgtttccac
    52741 gccagtacgc accagctaca tggagaaggt ggaagatttg gatacgacct gttgatggaa
    52801 cgtgaggtcc acggcagagg tctacatatt caccctgacg atagatagtc aaaccgcctt
    52861 cgtcttctga gtgttcttca atcaattcca acttgtaagg gtcatttttg aagatttcac
    52921 gtgcctcgtc tttagtcact tcttcacgaa tagatgggaa gttttctttg acgatttttt
    52981 gcatttcttc ttcgatacga ggaaggtctt cgttagagat ttgaccagct gtgttgtcag
    53041 tatcgtagta gaaaccatct tcgatggctg gaccaactcc caagtgaatg tctgggaaaa
    53101 gacgacgagc tgcttgggcg aacaagtgag ctgctgagtg acgcaagatt ggaagggcat
    53161 cttcgtgatc aggtgtcaca atttcgatgc ttccatcttc agtgatagcg cgagtagtgt
    53221 cgatgagttt gccgttgaat ttaccagcca aggctttttt agctagggaa ttgctgatag
    53281 attgggcaat ttcaaaagtt gttacgccag attcgaattc acgaacagcg ccatctggga
    53341 aagtaatgtt aatcatgatg ttctcctttt ttattatttc atagtttcta agcattgatt
    53401 ttttatcagc agactacttc caagtcctaa cgttcaattg cttttcttta tcagagagga
    53461 agttttccat ttccgtcaga atgtctatat ccaaacgttg agaaagttct aatagccacc
    53521 agatattttc tgaaagtttt tgttccagtg tgtagggtgt ttcatcatag tagcgtcctt
    53581 gctttgtcat caccagtcgt tggaaatttc caatatcatt agataaagcc aagaggtctt
    53641 cttctaccgt ccacttggaa tcatgatgct taacttccag ttcgtgataa gcttgtcgga
    53701 ttgcccaact gcgctccact aattcttgca actccataat tagtatccta ataaaaaaat
    53761 gcgacatcct cgaaaggacg tcgcaacgtg gttccacctt catttatgta cctcaaaaga
    53821 gagggacacc tctgattggc tctaacgtgg ccaccgtttt atgttttcat aaaaaactca
    53881 agagtagtat cagtttagac ttcctatgcg tttccagcaa ccacgcactc tctagtagaa
    53941 agggactaag tgacttgtct ctatggatta ttatagcatg attgtgagat ttttcaagga
    54001 ttttgtgaaa gttttttgtt tttcatattt tgtagaatat gcttgatgct aataccagaa
    54061 tccatgccca ccagagcaac tgtttcatag attagcaagt aaattagtat aaactcacca
    54121 aaggttatga tagtaaagta aaagagcagt ccgttaccaa ctaaccatca aagtgagaaa
    54181 cggaaacggt agctatagag taacgataca atcaagatta ccagaggtgt aaagaagaga
    54241 agattgttta tatagtgtaa gggggtcaga aacaactagc aagaacaact cataaagtgg
    54301 ccaataaaag aataatatga ccagatagta ggggagatgg gaatagaatc tacgcatgat
    54361 aatcacctcg ttttaaaaaa acagacaact tagatctctt gctatgatta ttatagcatg
    54421 tttaaaacaa gaaagtaaat ttgttgacaa agaagatttt tcttttcact agaatcatgg
    54481 ttagttttct tggtagaaat attttgataa taattaagca agactattga cattgattat
    54541 taagagtgtc acaattgttg taactaaaac aattacaaca agagaggtat aaaaaatgaa
    54601 actagcagtt attgcagcaa atggacaagc ggggaaggca attgttgaag aagcagtcaa
    54661 acgaggacat gaagtaacgg ctattgttcg ttctgaaaac aaaagtcaag ctgagtctat
    54721 tattaaaaaa gatttatttg agttgacaaa agatgatctt actggatttg atgctgttat
    54781 ttcagcgttt ggtgcttata caccagatac gctaccgctc cacagcaaat caatcgaact
    54841 atttaatcag cttcttgctg gaacacagac acgttttcta gttgtagggg gatcaggaag
    54901 cttttatata gatgaaacaa aaacgacacg acttttagat acgtctgatt ttcctgaaga
    54961 atttaagcca ctagcaaaag ctcaagcgga tgaattggat cttcttcgta caaaaaataa
    55021 tctcaactgg acttttgtca gtcctgctgt agattttatt cccgatggtg aaaaaacagg
    55081 aaactacatt ctagcaggag aaatttttac tactaatgaa aaaggaataa gccagattag
    55141 ttatgcagat tatgctattg gattggtaga tgaacttgaa aaaggtcatc atataaaaga
    55201 acgtatctct ttacttgaaa aataataact atgagagtat taatgtttga cagaaaattt
    55261 aaatcttggt aaaataggga ttgtcgtaaa gacaaataac ttcttcttgg ttacaggcat
    55321 gccaacctgt cactcggatg aagccaaata aaaaggagaa acatcatggc aatctcaaaa
    55381 gagaaaaaaa atgaaatcat cgcacaatat gcacgtcacg aaggtgatac aggttcagta
    55441 gaggttcaag ttgctgtcct tacttgggaa atcaaccacc ttaatgaaca catcaaacaa
    55501 cacaaaaaag accacgctac ttaccgtgga ttgatgaaaa aaatcggtcg ccgtcgtaac
    55561 ttgcttgcat acttgcgtaa aaacgacgtt aaccgttacc gtgagttgat caactctcta
    55621 ggacttcgtc gctaattcaa gatacaaagg ctgtcaaaag cacaaagcaa aaataggaaa
    55681 attgacgaag aaacttcagt ttctaggaga ttttatcttt tttgccaagt gcttaggccg
    55741 tgttcaattg agcatatctt gataatgaag ctactctaaa ttgggtagct tttttgcgtt
    55801 gtcaccttac ctcgatatac tcaagtataa tcttcggtta cggttcctag cactgtaagg
    55861 taaaataaac cagcttttct cccttcgggg agattttttt ttgtttcact gaaagtttcg
    55921 tacgatcttc gcctcgtcgc ctagtctata aacgatttat ccagcaagaa tcatgatgct
    55981 aagggcgtca aaaatccgta tgaaaatagg gaaatggcac agtgttcgat gaacgcaagg
    56041 agtttcatct ttttcactag gattttagtc cgggctcaaa tcagctctct gacttcagag
    56101 ggctttttta ttgaggtttt atcggtaaca attttggaga ctacaaaaac ctcaaatggt
    56161 atcagctaat tacaccataa aggtgcgcag ttactcggct tttcaagccg agtagctgta
    56221 tgcaagcccc ctagaagagc ccactcttta caaagtaaag tatagtatgt tatactttac
    56281 atggaagtag tcactgaatt ccagttagaa attactttgt aactacgttt tgaggaggag
    56341 taaaatgctt tcctacgttc gacattaccc actagcgata gctaaattaa tgtgtctgtg
    56401 ctctcctaaa atctgctgat ttattactga ctaatacagg aggttttttt atgggacaga
    56461 caatcatatc tgctattggt gtttatattt ccaccagtat cgattattta attattttaa
    56521 ttattttatt tgcacaacta tcacagaata aacagaaatg gcatatttat gcggggcaat
    56581 atctaggcac aggcttactt gtaggggcga gtttagttgc tgcttatgtc gttaatttcg
    56641 tgcctgaaga atggatggtt ggattgcttg gtttaatccc tatctattta gggattcgct
    56701 ttgcaattct tggagaagat gcggaagaag aagaggaaga aattattgaa agattggaac
    56761 aaagcaaggc aaatcaactg ttttggacag ttacattgct gacaattgcg tctggcggag
    56821 ataatttagg tatctatata ccttattttg cttcgttaga ttggtcacag accctcgtgg
    56881 ccttgcttgt gtttgtaatc ggcataatta tcttttgcga gattagtcgg gtgttatcct
    56941 ctattccgtt aatattcgag acaattgaaa aatacgagcg aatcattgtg cccttagtat
    57001 tcattctact tggactatac atcatgtatg aaaatggcac gatagagact tttctgatcg
    57061 tgtagatttt tttgtttcac taggatttta gcccgagctc aaatcagctc tctgattttc
    57121 agagggcttt ttcattgagt ataaatggac aatcttaaag ttactctatt gtagagtggc
    57181 ttttgatttg attaggagat tcttataaat atagtaaaat gaaacaaaaa caggacaaat
    57241 cgatcgtgac agtcaaatcg atttctaaaa atgttttaag aagtagaggt gtactattct
    57301 agtttcaatt tgatatataa atgaaaacct tagctgtttg gccaaggttc atttcttcta
    57361 tgcaagttct tctcttttct tatctgggtt ccagatgaag cttgcgataa agctaaagat
    57421 gatggttagg atagcgagga taatagcaag gatgagggca gggatgcgga taaaccacca
    57481 gagtggattt ggttttttat cattgtgcca ttgtttcgtt tcttcgtcca gacgttggaa
    57541 ttctgtttga atacgattgg cgactgtttc aatgccttca tcattcattt tcttgatatc
    57601 tgagatatcg attggatttc caaagttcat atcgacacgt tcacggctaa tcaagccctt
    57661 caaagtcatg ggaccggtgt aggtaaccgg catgatacgg accttggcca ttttggcaat
    57721 cagtgctgcg ccccccttga catcgtttga gtggcggcta ccacttggaa acatgatgag
    57781 agagcggtca ctttttttga gaacgttgat aggatatttg atggctgagg cgctgggatt
    57841 ttcacggtcg atgggaaagg cgccacacat acgaatccac caaccaaaga tacggttggt
    57901 aaagagttct ttttttgcca taaagatgaa ctgttttggc ttggtcgcaa aggccatata
    57961 aacaggatcc caccaggtac ggtgaggcgc aactaaaata taattttcat cttgattagg
    58021 aattttatca gtattatgat agtgagcatt gccattgatg gaccataaga gcaatacaac
    58081 taatccacgc aaataagtat aaaacatgcg atctccttcg attgttttct tgttattatt
    58141 ataccttatc aaaggagggc tggcaaactt ttcccttgac tagatgcata tttgggatga
    58201 aattagaatt ctgttaaaaa aaatgatata atagaattta tggataaaaa taagattatg
    58261 ggattaaccc aaagagaagt caaggaaaga caggctgagg gtttggtcaa tgactttacc
    58321 gcatcagcca gtaccagcac ttggcaaatc gttaaacgaa atgtctttac cctttttaac
    58381 gctttgaact ttgccattgc tttggccctt gcctttgtgc aggcttggag caatctggtc
    58441 ttctttgctg ttatctgctt taacgctttt tctgggattg tgaccgagct acgagccaaa
    58501 cacatggtgg acaagctcaa tctcatgacc aaggaaaagg tcaaaaccat ccgtgatggt
    58561 caggaagttg ctcttaatcc tgaagaatta gtgctaggag atgtcattcg tttgtctgca
    58621 ggagagcaga ttcctagtga tgccttggtt ttggaaggct ttgcggaagt caatgaagcc
    58681 atgttaacgg gagaaagtga tttggtgcaa aaggaagttg acggcttact tttgtcagga
    58741 agtttcctag ccagtgggtc agttttatct caagttcacc atgtcggtgc agacaactat
    58801 gctgccaaac tcatgcttga ggctaagacc gttaaaccca tcaactcccg tatcatgaaa
    58861 tcgctggaca agttggctgg ttttactggg aagattatca ttccctttgg tctggctctc
    58921 ttgctggaag ccttgctttt aaaaggcctg cctctcaagt catccgttgt aaactcgtcg
    58981 acagctcttt tgggaatgtt gcctaaggga attgcccttt tgaccattac ttcgctcttg
    59041 actgcagtga ttaagttggg cttgaaaaag gtcttggtgc aggagatgta ctctgttgag
    59101 accttggcgc gcgtggatat gctctgtctg gacaagacgg gcaccatcac ccaaggaaag
    59161 atgcaggtgg aggctgttct tccactgacg gaaacttacg gtgaagaggc tattgccagc
    59221 atcttgacta gctacatggc ccatagtgag gataagaatc caactgccca agccattcgc
    59281 cagcgttttg tgggagatgt tgcttatcct atgatttcca atcttccctt ctcgagcgac
    59341 cgcaagtggg gggctatgga gttagaaggc ttggggacag ttttcttagg ggcacctgag
    59401 atgttgctgg attctgaagt cccagaagcc agggaggcct tggagagagg atcacgtgtc
    59461 ttggtcttag ctctcagtca ggagaaatta gaccatcaca aaccacagaa accatctgat
    59521 attcaggctc tagccttgct ggaaatcttg gatcctattc gagagggagc ggcagagacg
    59581 ctgaactatc tccgttctca ggaagtgggg ctcaagatta tctctggtga caatccagtt
    59641 acggtatcca gcattgccca gaaggctggt tttgcggact atcacagcta tgtcgattgt
    59701 tcaaaaatca cggatgagga attgattgct ctggcggagg agacagcgat tttcggacgt
    59761 gtttcccctc atcaaaagaa actcattatc caaacgctga aaaaagcggg tcatacaaca
    59821 gctatgactg gggatggagt taatgatatc ctggctcttc gtgaggcgga ttgttctatc
    59881 gtaatggcgg agggagaccc ggcaacccgt cagattgcca acctggttct cttgaactca
    59941 gactttaatg atgttcctga gattcttttt gaaggtcgtc gtgtggtcaa taacattgcc
    60001 cacatcgctc cgattttctt gataaagacc atctattcct tcctgttagc agtcatctgt
    60061 attgccagtg ctttactagg tcggtcagag tggattttga ttttcccctt cattccgatc
    60121 cagattacca tgattgacca gtttgtggaa ggtttcccac catttgttct gacttttgag
    60181 cgaaatatca aacctgttga gccaaatttc ctcagaaaat ccatgcttcg tgccctacca
    60241 agtgccctca tggtcgtgtt tagcgttctt tttgtgaaaa tctttggaac gagtcaaggt
    60301 tggtctgagt tagaaatctc aactctcctc tattatctct tggggtcaat tggtttctta
    60361 tccgtattta gagcctgcat gccattcact ctatggcgag tcctcttgat tgtctggtca
    60421 gtaggaggct tcctagccac agctctcttc ccaagaatcc aaaaactgct tgaaatttca
    60481 accttgacag aacaaacgtt gcctgtttat ggtgtcatga tgttggtctt tacagtgatt
    60541 ttcatcctga ctagtcgcta tcaagctaga aaataaagaa agactgcaat ctgtggattg
    60601 cagtttttta tacgatggat ctatcgtaga tctgatgtgc aaggcctacg tgtctattat
    60661 ctatcggtga acccaagagt gattctcaag cctgcttgga ttgaggtaat agattcaaat
    60721 atctgtagtt agactatttg aagtttgatg taagaaagag aaagcgacag attgaagtaa
    60781 ttttaactct cttctattgc tagaacaaat ggtcggatag gttggtagtt tgaaaatgaa
    60841 gatgcaatct attgttaaat ggaacatagt gttatttatt agaaaatcgt ttggtttatt
    60901 tcttatcaaa tacgaaaagc aacttaaata tttcaactaa aatagatgtt atgaagaaaa
    60961 ggtaaaatga ttttggtata gtgaggttct gttctatttg atatcatatt tttgataaaa
    61021 acaaaaatgt ccattgcaaa ggacaaaatg cgaagtatat tattttttga aagcgatata
    61081 atggaatcat aaaggaggtg tatcgtgtct agaaaacaag aacaaatgga aacgttgttg
    61141 ctccttttgc gagatagtaa ggattatata tctgctaaag tattgggaga aaaattaaat
    61201 tgctctgata aaacggttta tcgccttgtc aaggtaatca acaaagattg tccggtagaa
    61261 gcattcattt tatctgaaaa aggcagaggt ttcaaattaa atccaagaag ttccctcgtg
    61321 gacgttgatg ggaattttac agaggctttt gatcctgaag taaggcgtga aaaattacta
    61381 gaacgtctct tgttgactgc tcctaagcca cattctattt atgatttagg agaggaattc
    61441 tacgtaagcg agtcagtagt actaaaagat cgtcagatat tacaagagag tctagcaatt
    61501 tatgggttag atttaaaaat gagacaacga aagcttttta ttgatgggga tgaggctcaa
    61561 attcgttcag ccattctaaa tctactgcca atgtttaatc agttggattt agagcaaatt
    61621 acacagaata aggttcagcc tcttgacgga gaacttgctc acttttgttt gggattactg
    61681 attacacttg agagagaatt gggggtaaac attccctatc catataatat aaatattttc
    61741 tctcacctgt atatttttat cagtaggaat cgtcgtagta ctagtattca tgttgtagca
    61801 ccttcaaaac ctactattgt tgatgagaaa atttacagtg tctgtcaaaa aattattcaa
    61861 gaaattgaac aatattttaa gatgaaggtt gatgcagttg agattgacta tctttatcaa
    61921 tacgttgtat cttcgagatt gcaaaaacca ttttcttccg ggaagcttcc tttttctcag
    61981 cgagttttag atgtcactca ttactatttt agccgtatgt gtatggacaa tagagagatt
    62041 gaaacgacag atcctgactt tgttgacttg gcgagtcata tcagtccctt actgaggaga
    62101 ttagataata gagtacagat taagaatagt cttttatcac aaattctttt aacctatcct
    62161 aatctagtta aagagttaac aactatttct aaagaagtga gtctagtatt tggttttgcg
    62221 tccttgagtc tggacgagat tggttttcta gtcttatatt ttgcacggtt tcaagaaaag
    62281 cgagcacgtc ctctaaaaac agtagtgatg tgtacatcag gtgtcggaac ttcagagctt
    62341 ttacgagcac gattagaaaa gcaatttact gaattggata ttattgatgt agttgcttat
    62401 catcaattag atgagctgat aaatctatat ccagatttag atttcattgt gacgacggta
    62461 gctttgcagg aaccagcaag tgtcccgttt gtcctagtta gtgtttttct aaccgagggt
    62521 gataaacaac gtcttcaagc aaaaattcag gagataaact atgaataatc tttcgcttgt
    62581 ccttatggat atatctgttc aaaatcgtca agaagcctac aaagaattag caaatcaaat
    62641 cagccttctt gtttctgaag atacagaaaa aatagaagag cttctatatt accgtgagag
    62701 acagggaagt atagaggttg ctaaaggtgt tcttctacca cattgtgaag gaaactttca
    62761 acatcatgtc ttagtgatta ctagattaaa atcacctatc agagaatggt cgaaggatat
    62821 ccagtgtgtt gaccttatta tcggtttggc cattgcagta tcacaggaca agtcatgtat
    62881 taaaacattg atgagaagac tagcagatga atcattcata aatcaattaa aacagttaac
    62941 aaaagaagaa ttacgggaga taatatatgg aaatcaaaga tattcttaat gtgagtctga
    63001 tccagacgga tttacagatg cagagcaaag aagaggtttt tgaggcatta gctcaactat
    63061 tggttgagac gggttatgtg tctgatagag accaatttat cgaaggtctg tatcagagag
    63121 aggcagaagg acagaccggt attgggaatt atattgctat tccccatagc aagagttctg
    63181 ctgtggagaa ggcgggggta gtcatagcta taaatcacaa tgagattcct tgggagacca
    63241 ttgatgggaa aggggtcaaa gtaattgtac tctttgcagt tggtgatgat acagaagctg
    63301 ctagggagca tttgaagacc ttatcactct ttgctcgaaa acttggtaat gacgaagttg
    63361 ttgccaaatt agttcgggct cagacatctg atgatgtgat tgcagctttt tgttaataag
    63421 aaaaaatttt ggagggtatc cgtatgaaaa ttgttggtgt tgcagcttgt actgtgggaa
    63481 ttgcccacac ttatattgca caggaaaaat tagagaatgc cgcaaaggta gctggacatg
    63541 tgattcatgt tgagactcag gggacaatag gggtagaaaa tgaattgagt caagagcaga
    63601 ttgatgcagc ggatgtagtt attttagcag ttgatgttaa gatttctggt atggaacgct
    63661 ttgagggtaa aaagattatc aaggttccaa cagaagtggc agtcaaatct cccaataaac
    63721 tgattgctaa agctgttgag attgttacga aataactgaa aatatttaag gagaaaatat
    63781 atgttgaaac acttaaactt aaaaggtcac ttattgacag ccatttccta tatgattcca
    63841 attgtttgtg gtgcaggatt cttagttgcc attggtttag caatgggggg tggtgttcct
    63901 gacgctcttg tagcaggaaa attcactatc tgggatgctt tagcaactat gggtggtaaa
    63961 gcccttggtc tcttgccagt tgttattgct acaggtttgt cttactcgat tgctggtaag
    64021 ccagggattg caccaggttt tgttgttggt ctaattgcca attctgttgg ttcagggttt
    64081 atcggtggta tcttgggagg ttatatagct ggtttcttgg ttcaagcgat tattaaaaag
    64141 gtcaaagtac caaactggat taaaggttta atgccaacct tgattattcc ttttgtagcc
    64201 tctttggtaa gtagtttgat tatgatttat attattggag cgcctatcgc agcctttacc
    64261 aactggttga cgagcttatt acaaagcttg ggaagtgctt caaatggttt gatgggggca
    64321 gttattggag ttctcagtgc tgttgacttt ggtggcccac ttaataaaac agtctatgcg
    64381 tttgtgttga ctttacaggc tgaaggtgtg aaagaaccat tgactgcttt gcaattggtg
    64441 aatactgcta caccagttgg atttggattg gcctatttta tcgcgaaatt actcaaaaaa
    64501 aatatctata ctcaagagga aatcgaaaca ttgaaatcgg ctgttcctat ggggattgtc
    64561 aatattgttg aaggtgtaat tccgattgtt atgaataact tggttccagg tctcattgca
    64621 acaggtatcg gtggtgctgt tggtggtgct gtttctttga caatgggtgc tgattctgcc
    64681 gtgccatttg gtggagtgct tatgttacca accatgactc gtccagtagc tggtatttgt
    64741 gctttgttag ccaacattgt agtcacagga cttgtctacg cgattttgaa aaaaccaata
    64801 aaacatacag aaccagttat gactgttgaa gaagagattg atttgtcaga tattgaaatt
    64861 ttgtaagagg gtaacgatgt caagaattga attttcacca tctttgatga ccatggattt
    64921 ggacaaattc aaagagcaga ttactttttt gaatgataaa gtagcatctt atcatatcga
    64981 tattatggat ggccattttg ttcccaatat taccttgtct ccttggttca ttcaagaagt
    65041 tcaaaaaatt agtgacacac ctttatcagt tcatctgatg gtcacagacc caaccttttg
    65101 ggtagatcaa gttctcgatt tacaatgtga gtatatttgt attcatgctg aagttctgaa
    65161 tggtcttgct tttcgtttga ttgataaaat tcatgatgca ggtctaaagg ctggtgttgt
    65221 ccttaatcct gaaacacctg tttctacaat ctttccctac attgatttac ttgacaaagt
    65281 aactattatg actgtagatc caggttttgc aggacaacgt tttttgaagt ctaccttgta
    65341 taaaatccaa gaactccgtc agcttagagt tcagaatggt tatcactaca tcattgagat
    65401 ggatggttct tcgagtcgta agactttcaa acaaattgat gtggcaggac cagatattta
    65461 tgttataggt cgcagtggat tatttggttt ggatgacgat attgccaaag cctgggatat
    65521 ctgttctaga gattacgaag aaatgaccgg aaaaacaatg ccaatcaaat aatggtttga
    65581 gaagaaattt attagttagg aggaatatat gtcactacaa tcagttaacg ccattcgttt
    65641 tcttggcgta gatgctatta acaaatctaa ttctggtcac ccgggaatcg tcatgggtgc
    65701 tgcgccaatg gcttatagct tatttacaaa acaccttaga attacacctg agcagccaaa
    65761 ctggattaac cgagatcgct ttatcttgtc tgcgggtcat ggatcaatgc tactgtatgc
    65821 tctcttgcat ttaacagggt ataaggatgt atccatggac gagattaaaa atttccggca
    65881 atggggatct aagacacctg gtcatcctga agtgacgcat acgtctggtg tggatgcgac
    65941 atctggtccg cttggtcagg ggatttctac tgccgttggt ttcgcccaag cagagcgttt
    66001 tttagctgct aagtacaaca aagatggttt tcctattttt gaccattata cttatgttat
    66061 cgctggagac ggtgacttca tggaaggagt gtctgcggag gcggcttctt atgcaggtca
    66121 tcaagcttta gataagctta tcgtcctcta cgactccaac gatatctgct tggatggtga
    66181 gaccaaagat actttctctg aaaatgttcg cgcccgttac gatgcttatg gttggcatac
    66241 agttctggta gaagatggaa cagatttagc agcaatttct acagcaattg agacggccaa
    66301 gttttctggt aagccgagtt tgattgaagt gaaaacggta attggttacg gctcacccaa
    66361 taaaagtggt acaaatgctg ttcatggtgc accactagga gcagaagaaa caggagcaac
    66421 tcgtaagttt ttgggatggg attacgatcc atttgaagta ccagaggaag tatattctga
    66481 tttcaagaca aatgtagcgg atcgtggtca ggaggcatac gatgcttggg ctagtttggt
    66541 gtctgattac aaggttgctt atcccgaagt tgctagtgag attgacgcta ttgtagctgg
    66601 aaaatcccct gtaaccatta ctgaaaaaga cttccctgtc tatgagaatg gcttctctca
    66661 agcaactcgt aattcgtccc aagatgctat taatacagca gcagcagttt taccaacctt
    66721 cttaggtgga tcggcagact tagctcactc caacatgacc tacatcaagg cagatggctt
    66781 acaagataaa tataatccat taaaccgcaa tattcagttt ggggtacgtg aatttgccat
    66841 gggaacaatc ctcaatggaa tggctcttca tggtggttta cgagtttatg gcggaacctt
    66901 ctttgttttc tctgactacg tcaaagctgc tattcggcta tcagccattc aggagttgcc
    66961 tgtaacttat gtctttaccc atgattcaat tgccgttggt gaagatggtc caactcatga
    67021 accagttgaa catttggcag gtttacgctc aatgccaaac ttgactgtta tccgtccagc
    67081 ggatgcccgt gaaactcaag cggcttggca tcatgccttg accagtacca ccactccaac
    67141 tgtcattgtc ttaacccgtc aaaacttggt agttgaagaa gggacagact ttggtaaggt
    67201 cgctaaagga gcctacgtcg tgtatgatac cccgggattt gatactatta tcattgctac
    67261 aggatctgag gtcaatctag ctatcaaagc tgctaaggaa ttggttttac aaggtggtaa
    67321 agtacgtgtg gtatctatgc cctcaaccga actatttgat gctcaagatg ctacctacaa
    67381 ggaagacatt ttaccatcta agactcgtcg tcgtgtggcc attgaaatgg cagcgaccca
    67441 aagttggtac aagtatgttg gtttggatgg cgcggtcatc ggtattgaca tcttcggtgc
    67501 gtctgcccca gctcagactg tgattgataa ttatggattt acggtagaga atatcgttgc
    67561 tcaagttaag tccctataga aaccaattac aatgaagata cagctgttgt cagactagca
    67621 gatgtagtga tagacactaa tcagatgatt ggttatttaa aaactataat gagaatgtaa
    67681 taatttatct acgaaagtta tagtagatag tatacacaat agagtatacc ctgaaacggt
    67741 tgcgaagtac gctaatcact ttgctactga tctagatagt ttctttaatc aataaacaca
    67801 gcatccacag attgacttag gatattgtaa gttttttgaa agctagagag aaggtctcta
    67861 aaattaaaaa acgcatagta taggatgttg aaatgatgaa ctgcccccca aaagttagac
    67921 agaaaaaatc taacttttgg ggtgttttat tatgaaatta agttatgaag ataaagttca
    67981 gatctatgaa ctaagaaagc aaggacaaag cttcaaacag ctttcaaaaa gatttggtgt
    68041 ggatgtttct ggtctaaagt acatggtgaa attaattgac cgttatggca tagagttcgt
    68101 caaaaaagga aaaaatcgtt actattctcc tgatttaaaa caagaaatga ttaataaagt
    68161 ct
//
LOCUS       DAVBOD010000004        66213 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 640-05
            SAMEA1012484-rid20186543.denovo.004, whole genome shotgun sequence.
ACCESSION   DAVBOD010000004 DAVBOD010000000
VERSION     DAVBOD010000004.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012484
            Sequence Read Archive: ERR059358
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 66213)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 66213)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979948.1
            Genome Coverage       :: 595x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:03:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,266
            CDSs (total)                      :: 2,219
            Genes (coding)                    :: 2,091
            CDSs (with protein)               :: 2,091
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 71 of 128
            Pseudo Genes (incomplete)         :: 50 of 128
            Pseudo Genes (internal stop)      :: 33 of 128
            Pseudo Genes (multiple problems)  :: 22 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..66213
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012484-rid20186543.denovo.004"
                     /strain="NIG 640-05"
                     /db_xref="taxon:1313"
     gene            1..397
                     /locus_tag="VQ862_000219"
                     /pseudo
     CDS             1..397
                     /locus_tag="VQ862_000219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix domain-containing
                     protein"
     gene            400..1412
                     /locus_tag="VQ862_000220"
                     /pseudo
     CDS             400..1412
                     /locus_tag="VQ862_000220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000182321.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Dyp-type peroxidase"
     gene            1387..1965
                     /locus_tag="VQ862_000221"
     CDS             1387..1965
                     /locus_tag="VQ862_000221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron permease"
                     /protein_id="HET3114632.1"
                     /translation="MVRNYWKARSWLLVLALSFLILSPVGAQESLSSYFVKITDTSKA
                     VKNGNQSEAQKLVQEMASDFERVENKDSEVGKIVKEKLALSGDITEAKLTEISSALLA
                     FEKEQNPVDLDAEKEKLVNRLSPRFETLEQAIASKDLEKVREAFKKMNSTWTINESVV
                     RDNSIAHYGRVETAISFLPSSMETEPTDESGT"
     gene            complement(2022..2306)
                     /locus_tag="VQ862_000222"
     CDS             complement(2022..2306)
                     /locus_tag="VQ862_000222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type B 50S ribosomal protein L31"
                     /protein_id="HET3114633.1"
                     /translation="MARKETMAERKYCKMKKDIHPEYRPVVFMDTTTGYQFLSGSTKR
                     SNETVEFEGETYPLIRVEISSDSHPFYTGRQKFTQADGRVDRFNKKYGLK"
     gene            complement(2360..3295)
                     /locus_tag="VQ862_000223"
     CDS             complement(2360..3295)
                     /locus_tag="VQ862_000223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional oligoribonuclease/PAP phosphatase
                     NrnA"
                     /protein_id="HET3114634.1"
                     /translation="MEICQQILEKIKEYDTIIIHRHMKPDPDALGSQVGLKALLEHHF
                     PEKTIKAVGFDEPTLTWMAEMDLVEDRAYQGALVIVCDTANTARIDDKRYSQGDFLIK
                     IDHHPNDDVYGDLSWVDTSSSSASEMITLFAQTTQLALADRDAELLFAGIVGDTGRFL
                     YPSTTARTLRLAAYLREHNFDFAALTRKMDTMSYKIAKLQGYIYDHLEVDENGAARVI
                     LSQEVLKQYNVTDAETAAIVSAPGRIDSVSLWGIFVEQADGHYRVRLRSKIHPINEIA
                     KEHDGGGHPLASGANSYSLEENEIIYQKLKNLLKN"
     gene            3399..3842
                     /locus_tag="VQ862_000224"
     CDS             3399..3842
                     /locus_tag="VQ862_000224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HET3114635.1"
                     /translation="MALAKIVFASMTGNTEEIADIVADKLRDLGLDVDVDECTTVDAS
                     DFLEADIAIVATYTYGDGELPDEMMDFYEDLADLNLNGKIYGVVGSGDTFYDEFCKAV
                     DDFDRVFVSTGAEKGSECVKVDLSAEEEDIERLEQFAEELVAKVG"
     gene            3958..4224
                     /locus_tag="VQ862_000225"
     CDS             3958..4224
                     /locus_tag="VQ862_000225"
                     /EC_number="5.4.99.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate mutase"
                     /protein_id="HET3114636.1"
                     /translation="MDLDIIRQEIDQIDDQIVKLLEERMHLVEGVVAYKKASGKPILD
                     TKREEVIFEKVGSRVEDKRYQETIVATFSDILKRSRDYQDQNIK"
     gene            4221..4595
                     /gene="crcB"
                     /locus_tag="VQ862_000226"
     CDS             4221..4595
                     /gene="crcB"
                     /locus_tag="VQ862_000226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000712114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fluoride efflux transporter CrcB"
                     /protein_id="HET3114637.1"
                     /translation="MKKEQFYPLGIFLAAMLGGLVRYLVSTWLPASPDFPWGTLFVNY
                     LGIFCLIYLVKGYLVYKGTSKGLILALGTGFCGGLTTFSSLMLDTVKLLDTGRYLSLI
                     LYLLLSIGGGLLLAYYLGRKKW"
     gene            4589..4918
                     /gene="crcB"
                     /locus_tag="VQ862_000227"
     CDS             4589..4918
                     /gene="crcB"
                     /locus_tag="VQ862_000227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000237393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fluoride efflux transporter CrcB"
                     /protein_id="HET3114638.1"
                     /translation="MVIVYLAIACGLGALVRYFFSRYNQVSKLPLGTLIANLLGCFLI
                     GVFYNHVESKEVYAILATGFCGGLTTFSTLNDELQRLLSDKKVFYSYLTLTYIGGLVA
                     IFLGILL"
     gene            5037..5384
                     /gene="rplS"
                     /locus_tag="VQ862_000228"
     CDS             5037..5384
                     /gene="rplS"
                     /locus_tag="VQ862_000228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L19"
                     /protein_id="HET3114639.1"
                     /translation="MNPLIQSLTEGQLRTDIPSFRPGDTVRVHAKVVEGNRERIQIFE
                     GVVIARKGAGISENYTVRKISNGVGVERIFPIHTPRVEKIEVVRYGKVRRAKLYYLRA
                     LQGKAARIKEIRR"
     gene            5426..5497
                     /locus_tag="VQ862_000229"
     tRNA            5426..5497
                     /locus_tag="VQ862_000229"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:5459..5461,aa:Arg,seq:cct)
     gene            complement(5663..6661)
                     /locus_tag="VQ862_000230"
     CDS             complement(5663..6661)
                     /locus_tag="VQ862_000230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001008999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAP domain-containing protein"
                     /protein_id="HET3114640.1"
                     /translation="MNFFSKLFNLKQNNHNRDTNSDCNNFYLNKLECGLTPGQLILID
                     WTQKTGRNYNFPRYFKYSLQIDPESTHNQLYKLGYFTKNKTLSYLKVVELKTILSKHN
                     LATSGKKAELITRIINNINVDKLDIPFEFKLTKEAQNLIIEHSDYIKAYYDKDISMED
                     YCKEKNNISFKATFGDIKWSLLNKQAHRNTVSGDFGCLSNTRKAQGRHLEQEGNIKHA
                     LIYYIESLIITISGLENNFSATDYPVYYPDSIPDYSLKHIQTLMESLSDDDYDFAFDE
                     ALFRFSILNANHFLSKEDIDYLRVNLPRSTAEEINNYLKKYECYSPLNNLELDDFE"
     gene            complement(6704..7510)
                     /gene="yidA"
                     /locus_tag="VQ862_000231"
     CDS             complement(6704..7510)
                     /gene="yidA"
                     /locus_tag="VQ862_000231"
                     /EC_number="3.1.3.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000023490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-phosphatase"
                     /protein_id="HET3114641.1"
                     /translation="MSIKLIAVDIDGTLVNSQKEITPEVFSAIQDAKEAGVKVVIATG
                     RPIAGVAKLLDDLQLRDQGDYVVTFNGALVQETATGHEIISESLTYEDYLDMEFLSRK
                     LGVHMHAITKDGIYTANRNIGTYTVHESTLVSMPIFYRTPEEMAGKEIVKCMFIDEPE
                     ILDAAIEKIPAEFYEHYSINKSAPFYLELLKKNVDKGSAITHLAEKLGLTKDETMAIG
                     DEENDRAMLEVVGNPVVMENGNPEIKKIAKYITKSNDESGVAHAIRTWVL"
     gene            complement(7523..8827)
                     /locus_tag="VQ862_000232"
     CDS             complement(7523..8827)
                     /locus_tag="VQ862_000232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001003495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HET3114642.1"
                     /translation="MNEKVFRDPVHNYIHVINQIIYDLINTKEFQRLRRIKQLGTSSY
                     TFHGGEHSRFSHCLGVYEIARRITEIFEEKYPEEWNPAESLLTMIAALLHDLGHGAYS
                     HTFEHLFDTDHEAITQEIIQSPETEIHQVLLQVAPDFPEKVASVIDHTYPNKQVVQLI
                     SSQIDADRMDYLLRDSYFTGASYGEFDLTRILRVIRPIENGIAFQRNGMHAIEDYVLS
                     RYQMYMQVYFHPATRAMEVLLQNLLKRAKELYPKDKDFFARTSPHLLPFFEKNVTLSD
                     YLALDDGVMNTYFQLWMTSPDKILADLSQRFVNRKVFKSITFSQEDQDQLASMRKLVE
                     DIGFDPDYYTAIHKNFDLPYDIYRPESENPRTQIEILQKNGELAELSSLSPIVQSLAG
                     SRHGDNRFYFPKEMLDQNSIFASITQQLLYLIENDHFTPNKN"
     gene            8899..9276
                     /locus_tag="VQ862_000233"
     CDS             8899..9276
                     /locus_tag="VQ862_000233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1934 domain-containing protein"
                     /protein_id="HET3114643.1"
                     /translation="MKIRMRNTIQFDEQLEVIDQLYDVEVHEKGDYSYLLFYNEEKEK
                     VVIKFHGQELVMSRFSNPKTIMRFLKNSDSLAYIPTPMGMQEFIIQTSHYQVDRQKIE
                     LDYQLQNQEGHPFASYQLEITWG"
     gene            9367..9699
                     /locus_tag="VQ862_000234"
     CDS             9367..9699
                     /locus_tag="VQ862_000234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009660419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA-binding protein"
                     /protein_id="HET3114644.1"
                     /translation="MEIEKTNRMNALFEFYAALLTDKQMNYIELYYADDYSLAEIAEE
                     FGVSRQAVYDNIKRTEKILEDYEMKLHMYSDYIVRSQIFDQILERYPKDNFLQEQIEI
                     LTSIDNRE"
     gene            9711..11282
                     /gene="ffh"
                     /locus_tag="VQ862_000235"
     CDS             9711..11282
                     /gene="ffh"
                     /locus_tag="VQ862_000235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle protein"
                     /protein_id="HET3114645.1"
                     /translation="MAFESLTERLQNVFKNLRKKGKISESDVQEATKEIRLALLEADV
                     ALPVVKDFIKKVRERAVGHEVIDTLNPAQQIIKIVDEELTAVLGSDTAEIIKSPKIPT
                     IIMMVGLQGAGKTTFAGKLANKLKKEENARPLMIAADIYRPAAIDQLKTLGQQIDVPV
                     FALGTEVPAVEIVRQGLEQAQTNHNDYVLIDTAGRLQIDELLMNELRDVKALAQPNEI
                     LLVVDAMIGQEAANVAREFNAQLEVTGVILTKIDGDTRGGAALSVRHITGKPIKFTGT
                     GEKITDIETFHPDRMSSRILGMGDMLTLIEKASQEYDEQKALEMAEKMRENTFDFNDF
                     IDQLDQVQNMGPMEDLLKMIPGMANNPALQNMKVDERQIARKRAIVSSMTPEERENPN
                     LLNPSRRRRIAAGSGNTFVEVNKFIKDFNQAKQLMQGVMSGDMNKMMKQMGINPNNLP
                     KNMPNMGGMDMSALEGMMGQGGMPDLSALGGAGMPDMSQMFGGGLKGKIGEFAMKQSM
                     KRMANKMKKAKKKRK"
     gene            complement(11477..12760)
                     /locus_tag="VQ862_000236"
     CDS             complement(11477..12760)
                     /locus_tag="VQ862_000236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007554578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil permease"
                     /protein_id="HET3114646.1"
                     /translation="MKQESTVDLLLDVDQRPSDGKGILLSFQHVFAMFGATILVPLIL
                     GMPVSVALFASGVGTLIYMIATGFKVPVYLGSSFAFITAMSLAMKEMGGDVSAAQTGV
                     ILTGLVYVLVATSIRFVGTKWIDKLLPPIIIGPMIIVIGLGLAGSAVTNAGLVADGNW
                     KNALVAVVTFLIAAFINTKGKGFLRIIPFLFAIIGGYLFALTLGLVDFTPVLKANWFE
                     IPGFYLPFSTGGAFKEYNLYFGPEAIAILPIAIVTISEHIGDHTVLGQICGRQFLKEP
                     GLHRTLLGDGIATSVSAFLGGPANTTYGENTGVIGMTRIASVSVIRNAAFIAIALSFL
                     GKFTALISTIPNAVLGGMSILLYGVIASNGLKVLIKERVDFAQMRNLIIASAMLVLGL
                     GGAILKLGPVTLSGTALSAMTGIILNLILPYENKD"
     gene            complement(13014..13727)
                     /gene="rsmG"
                     /locus_tag="VQ862_000237"
     CDS             complement(13014..13727)
                     /gene="rsmG"
                     /locus_tag="VQ862_000237"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(527)-N(7))-methyltransferase
                     RsmG"
                     /protein_id="HET3114647.1"
                     /translation="MKPETFYNLLAEQNLPLSNQQKEQFERYFELLVEWNEKINLTAI
                     TDKEEVYLKHFYDSIAPILQGLIPNETIKLLDIGAGAGFPSLPMKILYPELDVTIIDS
                     LNKRINFLQLLAQELDLNGVHFYHGRAEDFAQDKNFRAQYDFVTARAVARMQVLSELT
                     IPYLKVGGKLLALKASNAPEELLEAKNALNLLFSKVEDNLSYALPNRDPRYITVVEKK
                     KETPNKYPRKAGMPNKRPL"
     gene            13821..14381
                     /locus_tag="VQ862_000238"
     CDS             13821..14381
                     /locus_tag="VQ862_000238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LemA family protein"
                     /protein_id="HET3114648.1"
                     /translation="MTWIILGVIALIVIFVIVSYNGLVKNRMQTKEAWSQIDVQLKRR
                     NDLLPNLIETVKGYAKYEGSTLEKVAELRNQVAAATSPAEAMKASDALTRQVSGIFAV
                     AESYPDLKASANFVKLQEELTNTENKISYSRQLYNSVVSNYNVKLETFPSNIIAGMFG
                     FKAADFLQTPEEEKSVPKVDFSGLGD"
     gene            14383..15282
                     /gene="htpX"
                     /locus_tag="VQ862_000239"
     CDS             14383..15282
                     /gene="htpX"
                     /locus_tag="VQ862_000239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metalloprotease HtpX"
                     /protein_id="HET3114649.1"
                     /translation="MLFDQIASNKRKTWILLLVFFLLLALVGYAVGYLFIRSGLGGLV
                     IALIIGFIYALSMIFQSTEIVMSMNGAREVDEQTAPDLYHVVEDMALVAQIPMPRVFI
                     IDDPALNAFATGSNPQNAAVAATSGLLAIMNREELEAVMGHEVSHIRNYDIRISTIAV
                     ALASAITMLSGMAGRMMWWGGAGRRRSDDDRDGNGLEIIMLVVSLLAIVLAPLAATLV
                     QLAISRQREFLADASSVELTRNPQGMINALDKLDNSKPMSRHVDDASSALYINDPKKG
                     GGVQKLFYTHPPISERIERLKQM"
     gene            complement(15326..16885)
                     /locus_tag="VQ862_000240"
     CDS             complement(15326..16885)
                     /locus_tag="VQ862_000240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011681787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HET3114650.1"
                     /translation="MHYEHSRKGNSMIKINHLTITQNKDLRDLVSDLSMTIQDGEKVA
                     IIGEEGNGKSTLLKTLMGEALSDFTIKGNIQSDYQSLAYIPQKLPEELKKKTLHDYFF
                     LDSIDLDYSILYRLAEELHFDSNRFASDQEIGNLSGGEALKIQLIHELAKPFEILFLD
                     EPSNDLDLETVDWLKGQIQKTRQTVIFISHDEDFLSETADTIVHLRLVKHRKEAETLV
                     EHLDYDSYSEQRKANFAKQSQQAANNQRAYDKTMEKHRRVKQNVETALRATKDSTAGR
                     LLAKKMKTVLSQEKRYEKAAQSMTQKPLEEEQIQLFFSDIQPLPASKVLVQLEKENLS
                     IDDRVLVQKLQLTVRGQEKIGIIGPNGVGKSTLLAKLKQLLNDKREISLGFMPQDYHK
                     KLQLDLSPIAYISKTGEKEELQKIHSHLASLNFSYPEMQHQIRSLSGGQQGKLLLLDL
                     VLRKPNFLLLDEPTRNFSPTSQPQIRKLFATYPGGLITVSHDRRFLKEVCSIIYRMTE
                     HGLELVNLEDL"
     gene            17610..18152
                     /locus_tag="VQ862_000241"
     CDS             17610..18152
                     /locus_tag="VQ862_000241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF177 domain-containing protein"
                     /protein_id="HET3114651.1"
                     /translation="MKLNIQEIRKQSEGLNFEQTLDLVDDLRARNQEILDVKDILAVG
                     KVQYEDRMYFLDYQLSYTIVLASSRSMEPVELVESYPVTEVFMEGATNQLDQEVLDDD
                     LVLPIENGELDLAESVSDNILLNIPIKVLTAEEEAGQGFVSGNDWQIMTEEEYQAQQA
                     VKKEENSPFAGLQGLFDGDE"
     gene            18152..18781
                     /gene="nth"
                     /locus_tag="VQ862_000242"
     CDS             18152..18781
                     /gene="nth"
                     /locus_tag="VQ862_000242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000244461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease III"
                     /protein_id="HET3114652.1"
                     /translation="MVLSKKRARKVLEEIIALFPDAKPSLDFTNHFELLVAVMLSAQT
                     TDAAVNKATPGLFVAFPTPQAMSVATESEIASHISRLGLYRNKAKFLKKCAQQLLDDF
                     DGQVPQTREELESLAGVGRKTANVVMSVGFGIPAFAVDTHVERICKHHDIVKKSATPL
                     EVEKRVMDILPPEQWLAAHQAMIYFGRAICHPKNPECDQYPQLYDFSNL"
     gene            18992..19513
                     /gene="pyrR"
                     /locus_tag="VQ862_000243"
     CDS             18992..19513
                     /gene="pyrR"
                     /locus_tag="VQ862_000243"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional pyr operon transcriptional
                     regulator/uracil phosphoribosyltransferase PyrR"
                     /protein_id="HET3114653.1"
                     /translation="MKTKEVVDELTVKRAITRITYEIIERNKDLNKIVLAGIKTRGVF
                     IAHRIQERLKQLENLSVPVVELDTKPFRDDVKSGEDTSLVSVDVTDREVILVDDVLYT
                     GRTIRAAIDNIVGHGRPARVSLAVLVDRGHRELPIRPDYVGKNIPTSRSEEIIVEMTE
                     LDDQDRVLITEEA"
     gene            19532..20455
                     /locus_tag="VQ862_000244"
     CDS             19532..20455
                     /locus_tag="VQ862_000244"
                     /EC_number="2.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001293822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate carbamoyltransferase catalytic
                     subunit"
                     /protein_id="HET3114654.1"
                     /translation="MSENQQALNHVVSMEDLTVDQVMKLIKRGIEFKNGAQLPYEDHP
                     IVSNLFFEDSTRTHKSFEVAEIKLGLERLDFDVKTSSVNKGETLYDTILTLSALGVDV
                     CVIRHPEVDYYRELIASPTITTSIINGGDGSGQHPSQSLLDLMTIYEEFGHFEGLKVA
                     IAGDLDHSRVAKSNMQILKRLGSELFFAGPEEWRSQEFADYGQFVTIDEIIDQVDVMM
                     FLRVQHERHDSGAVFSKEDYHAQHGLTQERYDRLKETAILMHPAPINRDVEIADHLVE
                     APKSRIVQQMTNGVFVRMAILESVLASRNAN"
     gene            20505..21584
                     /gene="carA"
                     /locus_tag="VQ862_000245"
     CDS             20505..21584
                     /gene="carA"
                     /locus_tag="VQ862_000245"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing carbamoyl-phosphate
                     synthase small subunit"
                     /protein_id="HET3114655.1"
                     /translation="MTKRILVLEDGTVFEGKAFGADIDVTGEIVFNTGMTGYQESITD
                     QSYNGQILTFTYPLVGNYGINRDDYESIIPTCKGVVVFEEARRASNWRNQMTLDEFLK
                     AKKIPGISGIDTRALTKIIRKHGTMRATLTHVGDSMDHVTDQLQATVLPTDNIKQVST
                     KTSYPAPGVGLSVVLVDFGLKHSILRELSKRNCNVTVVPYSTTAEEILHLNPDGVMLS
                     NGPGNPEDVPQALDMIRGVQGKIPIFGICMGHQLFAMANGAKTYKMKFGHRGFNHAVR
                     EIATGRVDFTSQNHGYAVSREDLPEHLIITHEEINDKSVEGVRHRYQPAFSVQYHPDA
                     APGPHDASYLFDEFIEMMEVFKQSN"
     gene            21897..25073
                     /gene="carB"
                     /locus_tag="VQ862_000246"
     CDS             21897..25073
                     /gene="carB"
                     /locus_tag="VQ862_000246"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019803305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase large subunit"
                     /protein_id="HET3114656.1"
                     /translation="MPKRTDIQKIMVIGSGPIIIGQAAEFDYAGTQACLSLKEEGYEV
                     VLVNSNPATIMTDKEIADKVYIEPITLEFVTRILRKERPDALLPTLGGQTGLNMAMEL
                     SKNGILDELSVELLGTKLSAIDQAEDRDLFKQLMEELEQPIPESEIVNTVEEAVAFAA
                     TIGYPVIVRPAFTLGGTGGGMCANEKELREITENGLKLSPVTQCLIERSIAGFKEIEY
                     EVMRDSADNALVVCNMENFDPVGIHTGDSIVFAPAQTMSDYENQMLRDASLSIIRALK
                     IEGGCNVQLALDPNSFKYYVIEVNPRVSRSSALASKATGYPIAKLAAKIAVGLTLDEV
                     INPVTGSTYAMFEPALDYVVAKIPRFPFDKFEKGERRLGTQMKATGEVMAIGRNIEES
                     LLKACRSLEIGVHHNEIPELAAVSDDALIEKVVKAQDDRLFYVSEAIRRGYTPEEIAE
                     LTKIDIFYLDKLLHIFEIEQELGAHPQDLEVLKTAKLNGFSDRKIAELWGTTDDKVRQ
                     LRLENKIVPVYKMVDTCAAEFDSETPYFYSTYGWENESIRSDKESVLVLGSGPIRIGQ
                     GVEFDYATVHSVKAIQAAGYEAIIMNSNPETVSTDFSVSDKLYFEPLTFEDVMNVIDL
                     EQPKGVIVQFGGQTAINLAEPLAKAGVTILGTQVADLDRAEDRDLFEQALKELDIPQP
                     PGQTATNEEEAALAARKIGFPVLVRPSYVLGGRAMEIVENEEDLRSYMRTAVKASPDH
                     PVLVDSYIVGQECEVDAISDGKDVLIPGIMEHIERAGVHSGDSMAVYPPQTLSQKVQE
                     TIADYTKRLAIGLHCLGMMNIQFVIKDEKVYVIEVNPRASRTVPFLSKVTNIPMAQVA
                     TKLILGQSLSELGYQNGLYPESTRVHIKAPVFSFTKLAKVDSLLGPEMKSTGEVMGSD
                     ATLEKALYKAFEASYLHLPTFGNVVFTIADDAKEEALNLARRFQNIGYGILATEGTAA
                     FFASHGLQAQPVGKIGDDDKDIPSFVRKGRIQAIINTVGTKRTADEDGEQIRRSAIEH
                     GVPLFTALDTANAMLKVLESRSFVTEAI"
     gene            complement(25348..26157)
                     /locus_tag="VQ862_000247"
     CDS             complement(25348..26157)
                     /locus_tag="VQ862_000247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001199643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine transferase LicD"
                     /protein_id="HET3114657.1"
                     /translation="MQYLEKKEIKEIQLALLDYIDETCKKHDIPYFLSYGTMLGAIRH
                     KGMIPWDDDIDISLYREDYERLLKIIEEENHPRYKVLSYDTSSWYFHNFASILDTSTV
                     IEDHVKYKRHDTSLFIDVFPIDRFTDLSIVDKSYKYVALRQLAYIKKSRAVHGDSKLK
                     DFLRLCSWYALRFVNPRYFYKKIDQLVKNAVTNIPQYEGGVGIGKEGMKEIFPVDTFK
                     ELILTEFEGRMLPVPKKYDQFLTQMYGDYMTPPSKEMQEWYSHSIKAYRKN"
     gene            complement(26159..26962)
                     /locus_tag="VQ862_000248"
     CDS             complement(26159..26962)
                     /locus_tag="VQ862_000248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine transferase LicD"
                     /protein_id="HET3114658.1"
                     /translation="MKQLTIEDAKQIELEILDYIDTLCKKHNINYIINYGTLIGAVRH
                     EGFIPWDDDIDLSMPREDYQRFINIFQKEKSKYKLLSLETDKNYFNNFIKITDSTTKI
                     IDTRNTKTYESGIFIDIFPIDRFDDPKVIDTCYKLESFKLLSFSKHKNIVYKDSLLKD
                     WIRTAFWLLLRPVSPRYFANKIEKEIQKYSRENGQYMAFIPSKFKEKEVFPSGTFDKT
                     IDLPFENLSLPAPEKFDTILTQFYGDYMTLPPEEKRFYSHEFHAYKLED"
     gene            complement(26972..28459)
                     /gene="tacF"
                     /locus_tag="VQ862_000249"
     CDS             complement(26972..28459)
                     /gene="tacF"
                     /locus_tag="VQ862_000249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV teichoic acid flippase TacF"
                     /protein_id="HET3114659.1"
                     /translation="MKSIKLNALSYMGIRVLNIIFPILTGTYVARVLDRTDYGYFNSV
                     DTILSFFLPFATYGVYNYGLRAISNVKDNKKDLNRTFSSLFYLCIACTILTTAVYILA
                     YPLFFIDNPIVKKVYLVMGIQLIAQIFSIEWVNEALENYSFLFYKTAFIRILMLVSIF
                     LFVKNEHDIVVYTLVMSLSTLINYLISYFWIKRDIKLVKIHLSDFKPLFLPLTAMLVF
                     ANANMLFTFLDRLFLVKTGIDVNVSYYTIAQRIVTVIAGVVTGAIGVSVPRLSYYLGK
                     GDKEAYVSLVNRGSRIFNFFIIPLSFGLMVLGPNAILLYGSEKYIGGGILTSLFAFRT
                     IILALDTILGSQILFTNGYEKRITVYTVFAGLLNLGLNSLLFFNHIVVPEYYLLTTML
                     SETSLLVFYIIFIHRKQLIHLGHIFSYTVRYSLFSLSFVAIYFLINFVYPVDMVINLP
                     FLINTGLIVLLSAISYISLLVFTKDSIFYEFLNHVLALKNKFKKS"
     gene            28795..29502
                     /locus_tag="VQ862_000250"
     CDS             28795..29502
                     /locus_tag="VQ862_000250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-C-methyl-D-erythritol 4-phosphate
                     cytidylyltransferase"
                     /protein_id="HET3114660.1"
                     /translation="MIYAGILAGGTGTRMGISNLPKQFLELGDRPILIHTIEKFVLEP
                     SIEKIVVGVHGDWVSHAEDLVDKYLPLYKERIIITKGGADRNTSIKKIIEAIDAYRPL
                     TPEDIVVTHDSVRPFITLRMIQDNIQLAQNHDAVDTVVEAVDTIVESTNGQFITDIPN
                     RAHLYQGQTPQTFRCKDFMDLYGSLSDEEKEILTDACKIFVIKGKDVALAKGEYSNLK
                     ITTVTDLKIAKSMIEKD"
     gene            29507..30529
                     /locus_tag="VQ862_000251"
     CDS             29507..30529
                     /locus_tag="VQ862_000251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase catalytic
                     domain-containing protein"
                     /protein_id="HET3114661.1"
                     /translation="MINQIYQLTKPKFINVKYQEEAIDQENHILIRPNYMAVCHADQR
                     YYQGKRDPKILNKKLPMAMIHESCGTVISDPTGTYEVGQKVVMIPNQSPMQSDEEFYE
                     NYMTGTHFLSSGFDGFMREFVSLPKDRVVAYDAIEDTVAAITEFVSVGMHAMNRLLTL
                     AHSKRERIAVIGDGSLAFVVANIINYTLPESEIVVIGRHWEKLELFSFAKECYITDNI
                     PEELAFDHAFECCGGDGTGPAINDLIRYIRPQGTILMMGVSEYKVNLNTRDALEKGLI
                     LVGSSRSGRIDFKNAIQMMEVKKFANRLKNILYLEEPVREIKDIHRVFATDLNTAFKT
                     VFKWEV"
     gene            30546..31415
                     /gene="licA"
                     /locus_tag="VQ862_000252"
     CDS             30546..31415
                     /gene="licA"
                     /locus_tag="VQ862_000252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000411210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline kinase LicA"
                     /protein_id="HET3114662.1"
                     /translation="MEKIIKEKISSLLSQEEEVLSVEQLGGMTNQNYLAKTTNKQYIV
                     KFFGKGTEKLINRQDEKYNLELLKDLGLDVKNYLFDIEAGIKVNEYIESAITLDSTSI
                     KTKFDKIAPILQTIHTSAKELRGEFAPFEEIKKYESLIEEQIPYANYESVRNAVFSLE
                     KRLADLGVDRKSCHIDLVPENFIESPQGRLYLIDWEYSSMNDPMWDLAALFLESEFTS
                     QEEETFLSHYESDQTPVSHEKIAIYKILQDTIWSLWTVYKEEQGEDFGDYGVNRYQRA
                     VKGLASYGGSDEK"
     gene            31405..32283
                     /locus_tag="VQ862_000253"
     CDS             31405..32283
                     /locus_tag="VQ862_000253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000837620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HET3114663.1"
                     /translation="MKSKNGVPFGLLSGIFWGLGLTVSAYIFSIFTDLSPFVVAAAHD
                     FLSIFILLAFLLVKEGKVRLSIFLNIRNVSVIIGALLAGPIGMQANLYAVKYIGSSLA
                     SSVSAIYPAISVLLAFFFLKHKISKNTVFGIVLIIGGIIAQTYKVEQVNSFYIGILCA
                     LVCAIAWGSESVLSSFAMESELSEIEALLIRQVTSFLSYLVIVLFSHQSFTAVANGQL
                     LGLMIVFAAFDMISYLAYYIAINRLQPAKATGLNVSYVVWTVLFAVVFLGAPLDMLTI
                     MTSLVVIAGVYIIIKE"
     gene            32295..32984
                     /locus_tag="VQ862_000254"
     CDS             32295..32984
                     /locus_tag="VQ862_000254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NTP transferase domain-containing protein"
                     /protein_id="HET3114664.1"
                     /translation="MKAIILAAGLGTRLRPMTENTPKALVQVNQKPLIEYQIEFLKEK
                     GINDIIIIVGYLKEQFDYLKEKYGVRLVFNDKYADYNNFYSLYLVKEELANSYVIDAD
                     NYLFKNMFRNDLTRSTYFSVYREDCTNEWFLVYGDDYKVQDIIVDSKAGRILSGVSFW
                     DAPTAEKIVSFIDKAYASGEFVDLYWDNMVKDNIKELDVYVEELEGNSIYEIDSVQDY
                     RKLEEILKNEN"
     gene            33080..33928
                     /gene="dprA"
                     /locus_tag="VQ862_000255"
     CDS             33080..33928
                     /gene="dprA"
                     /locus_tag="VQ862_000255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-protecting protein DprA"
                     /protein_id="HET3114665.1"
                     /translation="MKITNYEIYKLKKSGLTNQQILKVLEYGENVDQELLLGDIADIS
                     GCRNPAVFMERYFQIDDAHLSKEFQKFPSFSILDDCYPWDLSEIYDAPVLLFYKGNLD
                     LLKFPKVAVVGSRACSKQGAKSVEKVIQGLENELVIVSGLAKGIDTAAHMAALQNGGK
                     TIAVIGTGLDVFYPKANKRLQDYIGNDHLVLSEYGPGEQPLKFHFPARNRIIAGLCRG
                     VIVAEAKMRSGSLITCERAMEEGRDVFAIPGSILDGLSDGCHHLIQEGAKLLTSGQDV
                     LAEFEF"
     gene            34812..35855
                     /locus_tag="VQ862_000256"
     CDS             34812..35855
                     /locus_tag="VQ862_000256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00341 family protein"
                     /protein_id="HET3114666.1"
                     /translation="MTNNKLYSLIEFRNKIYEELELSRSDLAILLCAMLIASIGLNMD
                     STPVIIGAMLISPLMTPILGVGLSLAIFDFKLLRKSFKILAIQILASLIASTLYFYLS
                     PISYASSEIVARTSPTIWDVLIAFVGGIAGIIGARKKETNNIVPGVAIATALMPPLCT
                     VGYAIASANLKFIIGSSYLFLINCSFIVIATYIGVRLMMVKKHYFKDNEEDSKMRRIL
                     LLVAVLLMIPSFISATTLVRETLKKESLKKFISEQFQGYNILKKTYSKKTHTLKLTIS
                     GNYLTEEELDMISSKRGDYGLSDVSVQVSQLSDSEQLSKEELVEHFFQYIKDKEAKEK
                     EKANKFDTESEEQ"
     gene            36022..38109
                     /gene="topA"
                     /locus_tag="VQ862_000257"
     CDS             36022..38109
                     /gene="topA"
                     /locus_tag="VQ862_000257"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000179642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I DNA topoisomerase"
                     /protein_id="HET3114667.1"
                     /translation="MATATKKKKSTVKKNLVIVESPAKAKTIEKYLGRNYKVLASVGH
                     IRDLKKSSMSVDIENNYEPQYINIRGKGPLINDLKKEAKKANKVFLASDPDREGEAIS
                     WHLAHILNLDENDANRVVFNEITKDAVKNAFKEPRKIDMDLVDAQQARRILDRLVGYS
                     ISPILWKKVKKGLSAGRVQSIALKLIIDRENEINAFQPEEYWTVDAVFKKGTKQFHAS
                     FYGVDGKKMKLTSNDEVKEVLSRLTSKDFSVDQVDKKERKRNAPLPYTTSSMQMDAAN
                     KINFRTRKTMMVAQQLYEGINIGSGVQGLITYMRTDSTRISPVAQNEAASFITDRFGS
                     KYSKHGSKVKNASGAQDAHEAIRPSSVFNTPESIAKYLDKDQLKLYTLIWNRFVASQM
                     TAAVFDTMAVKLSQKGVQFAANGSQVKFDGYLAIYNDSDKNKMLPDMVVGDVVKQVNS
                     KPEQHFTQPPARYSEATLIKTLEENGVGRPSTYAPTIETIQKRYYVRLAAKRFEPTEL
                     GEIVNKLIVEYFPDIVNVTFTAEMEGKLDDVEVGKEQWRRVIDAFYKPFSKEVAKAEE
                     EMEKIQIKDEPAGFDCEVCGSPMVIKLGRFGKFYACSNFPDCRHTQAIVKEIGVECPS
                     CHQGQIIERKTKRNRLFYGCNRYPECEFTSWDKPVGRDCPKCGNFLMEKKVRGGGKQV
                     VCSKGDYEEEKIK"
     gene            38330..38689
                     /locus_tag="VQ862_000258"
     CDS             38330..38689
                     /locus_tag="VQ862_000258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaN family protein"
                     /protein_id="HET3114668.1"
                     /translation="MRLIYLIIGFLSLALAIVGVVLPLLPTTPFLLLSIACFSRSSKR
                     FEDWLYHTKLYQTYVADFRETKSITRERKKKIIVSIYVLMGISIYFAPLLPVKIGLGA
                     LTIFITYYLFKVIPDKE"
     gene            38782..39414
                     /locus_tag="VQ862_000259"
     CDS             38782..39414
                     /locus_tag="VQ862_000259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000638771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper homeostasis protein CutC"
                     /protein_id="HET3114669.1"
                     /translation="MIYEFCAENVTLLEKAMQAGARRIELCDNLAVGGTTPSYGVTKA
                     AVELAANYDTTIMTMIRPRGGDFVYNDLEIAIMLEDICLTAQAGSQGVVFGALTADKK
                     LDKPNLEKLIAASKGMEIVFHMAFDELSDEDQPEAIDWLSQAGVTRILTRAGVSGDSL
                     EKRFVHYHRILEYAKGKIEILPGGGIDLDNRQTFIDQVGVTQLHGTKVVF"
     gene            39458..40114
                     /locus_tag="VQ862_000260"
     CDS             39458..40114
                     /locus_tag="VQ862_000260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000461593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MmcQ/YjbR family DNA-binding protein"
                     /protein_id="HET3114670.1"
                     /translation="MFEIFKSYQFNQEKAHDYGFIENSEVWTYSCQILQGDFVMTVSI
                     TADNLNFQVFDQETGDLYPHVHMESMRGSFVGNVREACLEILYQIRKACFDVQDFICH
                     QTKRIMTQVQEKYGNQLEYLWEKSPDTAVLRHEGNQKWYAVLMKISWNKLEKGREGQV
                     EAVNLKHDQVANLLSQKGIYPAFHMSKRYWISVSLDDTLSDEEVLELIEKSWNLTSKK
                     "
     gene            40133..40765
                     /locus_tag="VQ862_000261"
     CDS             40133..40765
                     /locus_tag="VQ862_000261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001010941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-isopropylmalate synthase"
                     /protein_id="HET3114671.1"
                     /translation="MNFQLAKYSLLKKFSENIGFTTPEECGAIFKYLIENVKTDRQII
                     YSPHCHDDLGMAVANSLAAVKNGAGRVEGTINGIRERAENAALEEIAVALNIRQDYYQ
                     VETSIVLNETINTSEMVSRFSGIPVPKNKAVVGGNTFSHESGIHQDGVLKNPLTYEII
                     TPELVGVKIPLGKLSGRHAFVEKLRELALDFTEEDIKPLFAKFKALADKK"
     gene            40793..41227
                     /locus_tag="VQ862_000262"
                     /pseudo
     CDS             40793..41227
                     /locus_tag="VQ862_000262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000225491.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase I"
     gene            41239..42276
                     /gene="leuB"
                     /locus_tag="VQ862_000263"
     CDS             41239..42276
                     /gene="leuB"
                     /locus_tag="VQ862_000263"
                     /EC_number="1.1.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydrogenase"
                     /protein_id="HET3114672.1"
                     /translation="MAKKIVALVGDGIGPEIMEAGLEVLEALAEKTGFDYEIDRRPFG
                     GADIDAAGPPLPDETLKASREADAILLAAIGSPQYDGAAVRPEQGLMALRKELNLYAN
                     IRPVKIFDSLKYLSPLKPERISGVDFVVVRELTGEIYFGDHILEERKARDINDYSYEE
                     VEWIIRKAFEIARNRRKILTSIDKQNVLATSKLWRKVAEEVAQDFSDVTLEHQLVDSA
                     AMLMITNPAKFDVIVTENLFGDILSDESSVLSGTLGVMPSASHSENGPSLYEPIYGSA
                     PDIAGQGIANPISMILSVAMMLRDSFGGYEDAERIKRAVETSLAAGILTRDIGGQAST
                     KEMTEAIIARL"
     gene            42273..42542
                     /locus_tag="VQ862_000264"
     CDS             42273..42542
                     /locus_tag="VQ862_000264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1294 domain-containing protein"
                     /protein_id="HET3114673.1"
                     /translation="MKLDEKITLVLLIWNVIIFLIYGIDKFKARRRAWRIQEKILLIL
                     ALTCGGFGAWLAGITFHHKTRKWYFKTVWFLGMVTTLVALYFIWR"
     gene            42546..42905
                     /gene="leuD"
                     /locus_tag="VQ862_000265"
     CDS             42546..42905
                     /gene="leuD"
                     /locus_tag="VQ862_000265"
                     /EC_number="4.2.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydratase small subunit"
                     /protein_id="HET3114674.1"
                     /translation="MAGSSREYAAWALADYGFKVVIAGSFGDIHYNNELNNGMLPIVQ
                     PREVREKLAQLKPTDQVTVDLEQQKIISPVEEFTFEIDSEWKHKLLNSLDDIGITLQY
                     EELIAAYEKQRPAYWQD"
     gene            43124..43267
                     /locus_tag="VQ862_000266"
     CDS             43124..43267
                     /locus_tag="VQ862_000266"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3114675.1"
                     /translation="MTSDKAGLERKFAAKERKRNKPGVVLCGSMDELCALAQLNPEIE
                     AFY"
     gene            43367..43540
                     /locus_tag="VQ862_000267"
     CDS             43367..43540
                     /locus_tag="VQ862_000267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001833765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3114676.1"
                     /translation="MTDVRGTSCFVIKFGKADEQLAAKLWEEGKMVYASSTSMIKRLK
                     LAMRARCNGVYGR"
     gene            43530..43691
                     /locus_tag="VQ862_000268"
     CDS             43530..43691
                     /locus_tag="VQ862_000268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001849983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3114677.1"
                     /translation="MVDKNGKLIPEQGGARSTSPAPVVIRKGLDIDKIMMHLSDTFNS
                     WDYRQVEYY"
     gene            43854..45785
                     /locus_tag="VQ862_000269"
     CDS             43854..45785
                     /locus_tag="VQ862_000269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="McrB family protein"
                     /protein_id="HET3114678.1"
                     /translation="MNKRKVSLEDFYKWYSLNKEKLLNKATVGEKFNDKLKEEFLQEW
                     PLDRILTMSIDEYVIGKGQQNKSLCYALEKGKYKNLFLGISGGSASKFGIYWNKKTNK
                     YKDQANNEISELDQRFSKLKSDLYEIIKEGIRFNFENPIFDMKRSTNEFIGRSAMVTK
                     LLCIYSGGDPFFGVNINSQKEFWNHFVSQTNQGGPYLQNHKIIELVSKTYPELEPSKL
                     GTMLFEYSKLFMENKEDNSTMDSSNNFRHQLTQSLLKSPNLILRGAPGTGKTYLAKEI
                     AKELTDGNEDQIGFVQFHPSYDYTDFVEGLRPVSNGDGAIEFRLQDGIFKDFCQKAKE
                     TQLIGGQDNFDEAWDSYLEYINVAEEKEYITKTSYLSVNSRQNLSVNYDSGVPGWSLP
                     SKYVYELYKDKNYNKQEYYKSGGKTVLETLRKRFGLKDYVSPTEIDTDKKFVFIIDEI
                     NRGEISKIFGELFFSIDPGYRGEKGSVSTQYANLHETDEKFYIPENVYIIGTMNDIDR
                     SVDTFDFAMRRRFRFVEVTAEGQVGMLDKELNIHAEEAKIRLRNLNAAIENVQELNSH
                     YHIGPSYFLKLKDVDFDYELLWSDYIKPLLEDYLRGSYDEVETLETLKKAFELTNNEQ
                     KDQAVADDNEGDENDDADY"
     gene            45772..47088
                     /locus_tag="VQ862_000270"
     CDS             45772..47088
                     /locus_tag="VQ862_000270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001223073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="McrC family protein"
                     /protein_id="HET3114679.1"
                     /translation="MRITDNQHKIIKEKFVEEYPKLSNLLLDRTLESLSQDERIFIFP
                     NDLTHTPDLDKDQKIFETVNQKIKTGNVIGFLGYGQERLTISSRFSDESNDHFLHYLL
                     NKVLHINLTSLDVALSREERLYQLLVYLFPKYLQAAIRKGLYKEYHRFSHNDSNVKGV
                     IDVRSHLKKNLPFTGNIAYATREFTYDNPLMQLVRHTIEYIKNQKSIGQGVLDNLSTS
                     RENVSEIVRVTPSYKLADRAKIIRGNQSKPIRHAYFHEYRNLQELCLMILNQEKHGLG
                     YQDQKIYGILFDVAWLWEEYVYTLLPKGFVHPRNKDKTDGISVFSVGKRKVYPDFYDR
                     ERKIVLDAKYKKLELTEKGINREDLFQLISYSYILKAEKAGLIFPSMEQSVNSEIGKV
                     AGYGAQLKKWSIRIPQNASFYSTFCKMMENSEENFKAIIDEEVGRK"
     gene            47263..48249
                     /locus_tag="VQ862_000271"
     CDS             47263..48249
                     /locus_tag="VQ862_000271"
                     /EC_number="1.7.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007516839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GMP reductase"
                     /protein_id="HET3114680.1"
                     /translation="MLNEFPIFDYEDIQLIPNKCVIKSRAEADTSVTLGNHTFKLPVV
                     PANMQTILDENVAEQLAKGGYFYIMHRFDEAGRIPFIKRMHDQGLIASISVGVKDYEY
                     DFVRQLKADAPEYITIDIAHGHADSVISMIQHIKKELPDTFVIAGNVGTPEAVRELEN
                     AGADATKVGIGPGKVCITKVKTGFGTGGWQLAALRWCAKAARKPIIADGGIRTHGDIA
                     KSIRFGASMIMIGSLFAGHIESPGKTIEVDGEQFKEYYGSASQYQKGAYKNVEGKRIL
                     LPAKGHLQDTLTEMEQDLQSAISYAGGRQVADLKHVDYVIVKNSIWNGDASH"
     gene            48313..48384
                     /locus_tag="VQ862_000272"
     tRNA            48313..48384
                     /locus_tag="VQ862_000272"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:48346..48348,aa:Arg,seq:ccg)
     gene            48567..49265
                     /locus_tag="VQ862_000273"
     CDS             48567..49265
                     /locus_tag="VQ862_000273"
                     /EC_number="3.1.26.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease III"
                     /protein_id="HET3114681.1"
                     /translation="MKELQTVLKNHFAIEFADKNLLETAFTHTSYANEHRLLKISHNE
                     RLEFLGDAVLQLLISEYLYKKYPKKPEGDLSKLRAMIVREESLAGFARDCQFNQFIKL
                     GKGEEKSGGRNRDTILGDAFEAFLGALLLDKDVAKVKEFIYQVIIPKVEAGEFEMITD
                     YKTHLQELLQVNGDVAIRYQVISETGPAHDKVFDVEVLVEGKSIGQGQGRSKKLAEQE
                     AAKNAVEKGLDSCI"
     gene            49256..52795
                     /gene="smc"
                     /locus_tag="VQ862_000274"
     CDS             49256..52795
                     /gene="smc"
                     /locus_tag="VQ862_000274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000280891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein SMC"
                     /protein_id="HET3114682.1"
                     /translation="MYLKEIEIQGFKSFADKTKVVFDQGVTAVVGPNGSGKSNITESL
                     RWALGESSVKSLRGGKMPDVIFAGTESRKPLNYASVVVTLDNHDGFIKDAGQEIRVER
                     HIYRSGDSEYKIDGKKVRLRDIHDLFLDTGLGRDSFSIISQGKVEEIFNSKPEERRAI
                     FEEAAGVLKYKTRRKETESKLQQTQDNLDRLEDIIYELDNQIKPLEKQAENARKFLDL
                     EGQRKAIYLDVLVAQIKENKAELESTEEELTQVQELLMSYYQKREKLEEENQTLKKQR
                     QDLQAEMAKDQGSLMDLTSLISDLERKLALSKLESEQVALNQQEAQARLAALEDKRNS
                     LSKEKSDKESSLALLEGNLVQNNQKLNRLEAELLAFSDDPDQMIELLRERFVALLQEE
                     ADVSNQLTRIENELENSRQLSQKQADQLEKLKEQLAIAKEKASQQKEELETAKEQVQK
                     LLADYQAIAKEQEEQKTSYQAQQSQLFDRLDSLKNKQARAQSLENILRNHSNFYAGVK
                     SVLQEKDRLGGIIGAVSEHLTFDVHYQTALEIALGASSQHIIVEDEESATKAIDFLKR
                     NRAGRATFLPLTTIKARTISSQNQDVIAVSPGFLGMADELVTFDTRLEAIFKNLLATT
                     AIFDTVEHARAAARQVRYQVRMVTLDGTELRTGGSYAGGANRQNNSIFIKPELEQLQK
                     EIAADEASLGSEEAALKTLQDQMATLTERLEAIKSQGEQARIQEQGLSLAYQQTSQQV
                     EELETLWKLQEEEKDRLSDGDWQADKENCQERLAAIASDKQNLEAEIEEIKSNKNAIQ
                     ERYQNLQEELAQARLLKTELQGQKRYEVADIERLGKELDNLDFEQEEIQRLLQEKVDN
                     LEKVDTELLSQQAEESKTQKTNFQQGLIRKQFELDDIEGQLDDIASHLDQARQQNEEW
                     IRKQTRAEAKKEKVSERLRHLQSQLTDQYQISYTEALEKAHELENLNLAEQEVKDLEK
                     AIRSLGPVNIEAIDQYEEVRNRLDFLNSQRDDILSAKNLLLETITEMNDEVKERFKST
                     FEAIRESFKVTFKQMFGGGQADLILTEGDLLTAGVEISVQPPGKKIQSLNLMSGGEKA
                     LSALALLFSIIRVKTIPFVILDEVEAALDEANVKRFGDYLNRFDKDSQFIVVTHRKGT
                     MAAADSIYGVTMQESGVSKIVSVKLKDLESIEG"
     gene            52792..53586
                     /locus_tag="VQ862_000275"
     CDS             52792..53586
                     /locus_tag="VQ862_000275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000153012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HET3114683.1"
                     /translation="MTIKLVATDMDGTFLDENGRFDMDRLKSLLASYKEKGIYFAVAS
                     GRGFLSLEKLFADVRDDIIFIAENGSLVEYQGQDLYEATMSRDFYLATFEKLKTSPYV
                     DINKLLLTGKKGSYVLDTVDETYLKVSQHYNENIQKVASLEDITDDIFKFTTNFTEET
                     LEAGEAWVNDNVPGVKAMTTGFESIDIVLDYVDKGVAIVELAKKLGITMDQVMAFGDN
                     LNDLHMMQVVGHPVAPENARPEILELAKTVIGHHKERSVIAYMEGL"
     gene            53586..54404
                     /locus_tag="VQ862_000276"
     CDS             53586..54404
                     /locus_tag="VQ862_000276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HET3114684.1"
                     /translation="MADIKLIALDLDGTLLTTDKRLTDRTKSTLKAARDRGIKVVLTT
                     GRPLKAMDFFLHELGTDGHEDEYTITFNGGLVQKNTGEILDKTVFSYADVARLYEETE
                     KLSLPLDAISEGTVYQIQSDQESLYAKFNPALTFVPVDFEDLSSQMTYNKCVTAFAQE
                     PLDAAIQKISPELFDQYEIFKSREMLLEWSPKNVHKATGLAKLISHLGIDQSQVMACG
                     DEANDLSMIEWAGLGVAMQNAVPEVKAAANVVTPMTNDEEAVAWAIEEYVLKEN"
     gene            54408..55697
                     /gene="ftsY"
                     /locus_tag="VQ862_000277"
     CDS             54408..55697
                     /gene="ftsY"
                     /locus_tag="VQ862_000277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000522312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle-docking protein
                     FtsY"
                     /protein_id="HET3114685.1"
                     /translation="MGLFDRLFGKKEEPKIEEVVKEALENLDLSEDVDPTFTEVEEVS
                     QEEAEMEIVEQAVFQEEEIQDTVEESLDLEPVVEVSQKEVEEFPNSQEVTEEEKLEHE
                     GTVEENNSEVLEPEAPQTEETVQEKYDRSLKKTRTGFGARLNAFFANFRSVDEEFFEE
                     LEELLIMSDVGVQVASNLTEELRYEAKLENAKKPDVLRRVIIEKLVELYEKDGSYDES
                     IHFQDNLTVMLFVGVNGVGKTTSIGKLAHRYKRAGKKVMLVAADTFRAGAVAQLAEWG
                     RRVDVPVVTGPEKADPASVVFDGMERAVAEGIDILMIDTAGRLQNKDNLMAELEKIGR
                     IIKRVVPEAPHETFLALDASTGQNALVQAKEFSKITPLTGIVLTKIDGTARGGVVLAI
                     REELNIPVKLIGFGEKIDDIGEFNSENFMKGLLEGLI"
     gene            complement(55743..57230)
                     /locus_tag="VQ862_000278"
     CDS             complement(55743..57230)
                     /locus_tag="VQ862_000278"
                     /EC_number="1.1.1.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000096131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate dehydrogenase"
                     /protein_id="HET3114686.1"
                     /translation="MSSKVIVTIFGASGDLAKRKLYPSLFRLYKSGNLSKHFAVIGTA
                     RRPWSKEYFESVVVESILDLADSTEQAQEFASHFYYQSHDVNDSEHYIALRQLQAELN
                     EKYQAEHNKLFFLSMAPQFFGTIAKHLKSENIVDGKGFERLIVEKPFGTDYATASKLN
                     DELLATFDEEQIFRIDHYLGKEMIQSIFAVRFANLIFENVWNKDFIDNVQITFAERLG
                     VEERGGYYDQSGALRDMVQNHTLQLLSLLAMDKPASFTKDEIRAEKIKVFKNLYHPTD
                     EELKEHFIRGQYRSGKIDGIKYISYRSEPNVNPESTTETFTSGAFFVDSDRFRGVPFF
                     FRTGKRLTEKGTHVNIVFKQMDSIFGEPLAPNILTIYIQPTEGFSLSLNGKQVGEEFN
                     LAPNSLDYRTDATATGASPEPYEKLIYDVLNNNSTNFSHWDEVGASWKLIDRIEKLWA
                     ENGAPLHDYKAGSMGPQASFDLLEKFGAKWTWQPDIAYRQDGRLE"
     gene            complement(57379..58119)
                     /locus_tag="VQ862_000279"
     CDS             complement(57379..58119)
                     /locus_tag="VQ862_000279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HET3114687.1"
                     /translation="MAKLKIDVNDLHKHYGKNEVLKGITTKFYEGDVVCIIGPSGSGK
                     STFLRSLNLLEEVTSGHITVNGYDLTEKTTNVDHVRENIGMVFQHFNLFPHMSVLDNI
                     TFAPIEHKLMTKEEAEKLGMELLEKVGLADKANANPDSLSGGQKQRVAIARGLAMNPD
                     IMLFDEPTSALDPEMVGDVLNVMKELAEQGMTMIIVTHEMGFARQVANRVIFTADGEF
                     LEDGTPDQIFDNPQHPRLKEFLDKVLNV"
     gene            complement(58119..60284)
                     /locus_tag="VQ862_000280"
     CDS             complement(58119..60284)
                     /locus_tag="VQ862_000280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HET3114688.1"
                     /translation="MKKKFLAFLLILFPIFSLGIAKAETIKIVSDTAYAPFEFKDSDQ
                     TYKGIDVDIINKVAEIKGWNIQMSYPGFDAAVNAVQAGQADAIMAGMTKTKEREKVFT
                     MSDTYYDTKVVIATTKSHKISKYDQLTGKTVGVKNGTAAQRFLETIKDKYGFTIKTFD
                     TGDLMNNSLSAGAIDAMMDDKPVIEYAINQGQDLHIEMDGEAVGSFAFGVKKGSKYEH
                     LVTEFNQALSEMKKDGSLDKIIKKWTASSSSAVPTTTTLAGLKAIPVKAKYIIASDSS
                     FAPFVFQNSSNQYTGIDMELIKAIAKDQGFEIEITNPGFDAAISAVQAGQADGIIAGM
                     SVTDARKATFDFSESYYTANTILGVKESSNIASYEDLKGKTVGVKNGTASQTFLTENQ
                     SKYGYKIKTFADGSSMYDSLNTGAIDAVMDDEPVLKYSISQGQKLKTPISGTPIGETA
                     FAVKKGANPELIEMFNNGLANLKANGEFQKILDKYLASESSTASTSTVDETTLWGLLQ
                     NNYKQLLSGLGITLALALISFAIAIVIGIIFGMFSVSPYKSLRVISEIFVDVIRGIPL
                     MILAAFIFWGIPNFIESITGQQSPINDFVAGTIALSLNAAAYIAEIVRGGIQAVPVGQ
                     MEASRSLGISYGKTMRKIILPQATKLMLPNFVNQFVIALKDTTIVSAIGLVELFQTGK
                     IIIARNYQSFKMYAILAIFYLVIITLLTRLAKRLEKRIR"
     gene            60457..61410
                     /locus_tag="VQ862_000281"
     CDS             60457..61410
                     /locus_tag="VQ862_000281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000792120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET3114689.1"
                     /translation="MKNKRIFKDFQASKMSLNIYTSPLLAFVFVFIGEFVAFTLYGIG
                     LLALIGLARNFGEAGQNLATYLQTLHQSLTDKTSDFRLILGLLAFGFILNTVFRWTRK
                     VEKRPIRTLGFYRENFLSNLLKGFSLGLALFLLTLLGLVVLGQYRLESIHLNPYSLAF
                     VVFTIPFWILQGTAEEVVARAWLLPQLASRTNLKLAILISSLFFTLLHMGNSGLTPLS
                     LVNLFLFGVAMALYLLKTDTVWGVAGIHGAWNFAQGNLFGILVSGQPSGTSLMTFLPQ
                     GNQDWLSGGSFGIEGSIMTSLVLLLLIVYLANKLKKENERM"
     gene            61487..63475
                     /gene="uvrB"
                     /locus_tag="VQ862_000282"
     CDS             61487..63475
                     /gene="uvrB"
                     /locus_tag="VQ862_000282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit B"
                     /protein_id="HET3114690.1"
                     /translation="MINHITDNQFKLVSKYQPSGDQPQAIEQLVDNIEGGEKAQILMG
                     ATGTGKTYTMSQVISKVNKPTLVIAHNKTLAGQLYGEFKEFFPENAVEYFVSYYDYYQ
                     PEAYVPSSDTYIEKDSSVNDEIDKLRHSATSALLERNDVIVVASVSCIYGLGSPKEYA
                     DSVVSLRPGLEISRDKLLNDLVDIQFERNDIDFQRGRFRVRGDVVEIFPASRDEHAFR
                     VEFFGDEIDRIREVEALTGQVLGEVDHLAIFPATHFVTNDDHMEVAVAKIQAELEEQL
                     AVFEKEGKLLEAQRLKQRTEYDIEMLREMGYTNGVENYSRHMDGRSEGEPPYTLLDFF
                     PDDFLIMIDESHMTIGQIKGMYNGDRSRKEMLVNYGFRLPSALDNRPLRREEFESHVH
                     QIVYVSATPGDYENEQTETVIEQIIRPTGLLDPEVEVRPTMGQIDDLLGEINARVEKN
                     ERTFITTLTKKMAEDLTDYFKEMGIKVKYMHSDIKTLERTEIIRDLRLGVFDVLVGIN
                     LLREGIDVPEVSLVAILDADKEGFLRNERGLIQTIGRAARNSEGHVIMYADTVTQSMQ
                     RAIDETARRRKIQMAYNEEHGIVPQTIKKEIRDLIAVTKAVAKEEDKEVDINSLNKQE
                     RKELVKKLEKQMQEAVEVLDFELAAQIRDMMLEVKALD"
     gene            63485..64048
                     /locus_tag="VQ862_000283"
     CDS             63485..64048
                     /locus_tag="VQ862_000283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET3114691.1"
                     /translation="MIYLRKLKKEDLMSLWEMAYSQLNPVWKQYDAPYYDDYQYFSNF
                     KEFELQKSESILSNSNRLGIFVDDKLVGTVSRYWVCKETRWMELGIGIYDKKFWNTGI
                     GKVAMLQWIDRTFQDYLELEHLGLTTWSGNLGMMKLAEKLRMKKEAHIPKVRYYQGKY
                     FDSIKYGILREDWEKINDGYYQINGNS"
     gene            64014..64502
                     /locus_tag="VQ862_000284"
     CDS             64014..64502
                     /locus_tag="VQ862_000284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET3114692.1"
                     /translation="MTVIIKSMETPEEIEGKSLVHWQTWREAYDDLLPAEFQETMTLE
                     RCRFFSQKYPENTLIAIGDLKVVGFISYGNFRDDTIQAGGIIALYVLKDYYGKGIAQK
                     LMKAALTALNHFSEIFLWVLKDNKRAIAFYQKMGFTFDGQEKILELGKPIKEKRMVFY
                     SK"
     gene            64576..65043
                     /locus_tag="VQ862_000285"
     CDS             64576..65043
                     /locus_tag="VQ862_000285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000085289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HET3114693.1"
                     /translation="MSRSQLTILTNICLIEDLETQRVVMQYRAPENNRWSGYAFPGGH
                     VENDEAFAESVIREIYEETGLTIQNPQLVGIKNWPLDTGGRYIVICYKATEFSGTLQS
                     SEEGEVSWVQKDQIPNLNLAYDMLPLMEMMEAPDKSEFFYPRRTEDDWEKKIF"
     gene            complement(65040..65555)
                     /locus_tag="VQ862_000286"
     CDS             complement(65040..65555)
                     /locus_tag="VQ862_000286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription repressor NadR"
                     /protein_id="HET3114694.1"
                     /translation="MTKDRKQALLQLLKEAPKALNGQSLAEHFHVTRQVIVQDIAILR
                     ADGAPILSTNRGYIYKQIDTNPYVHKLFKVKHEVEEIGQELLAIVDNGGHVQNTLIDH
                     PVYGEIETLLKLSCRRDVQHFLEQVEHSDFRPLSELTDGIHYHLVEAETQQDLHYIEE
                     ALDQLGYLVKD"
     gene            complement(65567..66094)
                     /locus_tag="VQ862_000287"
     CDS             complement(65567..66094)
                     /locus_tag="VQ862_000287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HET3114695.1"
                     /translation="MNTRKKTQFMTMTALLTAIAILIPIVMPFKIVIPPASYTLGSHI
                     AIFIAMFLSPLMAVFVILASSFGFLMAGYPMVIVFRAFSHISFGALGALYLQKFPDTL
                     DKPKSSWVFNFVLAVVHALAEVLACVLFYATSGTNVENMFYVLFVLVGFGTIIHSMVD
                     YTLALAVYKVLRKRR"
BASE COUNT        20125 a        11879 c        14504 g        19705 t
ORIGIN      
        1 acaacgattt ggcgaaatgt aaaaaaatat gaggagttcg gactcgactc tctctttcaa
       61 gaaacacgtg gtggtcgtaa ccatgcatat atgacggttg agcaagagaa agcctttctt
      121 gctcgccatt tgaaggctgc agaggcagga gaatttgtta caattgatgc cttatatcag
      181 gcttataaaa aggagttagg tcgttcctac acacgtgatg ccttctatca actgttgaag
      241 caccatggtt ggcgaaatat tatgccacgt ccagaacatc ctaggaaagc agacgctcaa
      301 accattgtcg cgtctaaaaa taaaatctta attcaagaag acaagaaagc gctttaaata
      361 tagtagacgt tttcgtaagg ttcgcttgat gtaccaaata gtacgcccat gcaaaagaat
      421 atctattttg ttgtcttgga cctgcatacg acggatagag ataaaattat ccagctattc
      481 aaggattgga cggattatag tgccaagttg gtcgaggggg aattggttaa aaaagatgga
      541 cagaatgctc tctttcctcc gagcgatact ggtgagacag ttgggctcaa tcctcatcgt
      601 ttgacgctga cttttggtgt atctgcaagt ttcttgaaaa agatgaactt ggaaaacaag
      661 cgccctcgac tgttcaggga tttacctcta tttcctaagg agcaattacg tgaaaaatat
      721 actggtggag atattgtgat tcatgcttgt gcagatgatg agcaaattgc ctttcacgct
      781 attcgcaatc tcatacgtaa ggggagaaat gcggtgcccc ttcgttggag tcagtctgga
      841 tttgcagcta tcggggaccg aatggagact ccgcggaacc tctttggttt taaggatgga
      901 acagcaaatc caaccaagga gcaagacttt gaccgcgtta tctgggctga tagtaaggac
      961 tggatggaaa atggttctta tatggcagtt cgtcggattc agatgttttt agagacctgg
     1021 gaccgcactg gtctctaaga acaagaaaat acctttggtc gttacaagga aagtagtgcc
     1081 cctttcggta aaaaaatgag tttgatgaag tgaatttgag ttttttgcta gatgattcgc
     1141 atgttcgttt ggctaagtaa gtggacaagc cacttttgcg ttgttcttac tcttactcag
     1201 atggcattga tgaaaagact ggtcagtttg atacgggttt gctcttcatt tctttccaga
     1261 aggatcctga taactttgtt aaggttcaaa ctaatctagg tgctactgat aagatgaatg
     1321 aatacatcac tcacataggt agtggacttt ttacttgctt tggtggtgtg gagaaaggag
     1381 actacattgg tcagaaatta ttggaaagct aggagctggt tgcttgtttt agctttgtca
     1441 tttttaattc tttccccagt aggtgcccaa gaaagtttga gttcttattt cgtaaaaatc
     1501 acagatactt ctaaagcggt caaaaatggc aatcagtctg aggcccagaa acttgttcaa
     1561 gagatggcat cagacttcga aagagtagaa aataaggatt ctgaggttgg taagattgtt
     1621 aaggaaaagt tagctctatc tggagatatt actgaagcca aactcaccga aatttcctca
     1681 gctctattag cttttgaaaa agaacaaaat cctgttgacc tagatgcgga aaaggaaaaa
     1741 ttggtaaacc gtctaagtcc tcgttttgaa accttagagc aggccattgc ctccaaagat
     1801 ttggaaaaag tccgagaagc ttttaagaaa atgaattcca cttggaccat caatgaaagt
     1861 gtggttcgtg acaatagtat agctcattat ggacgtgttg aaacagctat ttccttcctg
     1921 cctagtagca tggaaaccga acctacagat gagtctggaa catgaaaaca gcagttgatt
     1981 tcaagaaaca aaaaggaaca gccgaaactg ttctcttatc attatttgag accgtatttt
     2041 ttgttgaaac gatccacgcg tccatctgct tgagtgaact tttgacgtcc agtgtagaat
     2101 gggtgtgagt ctgatgaaat ttccacacgg atcaatgggt aagtctcgcc ttcgaactca
     2161 actgtttcgt tagagcgttt tgttgaaccg ctaaggaatt ggtaaccagt agttgtgtcc
     2221 atgaagacaa ctgggcgata ttctggatgg atatcttttt tcattttgca atatttcctt
     2281 tctgccatgg tctctttgcg agccatagat tgttaccata ctagtctatc agattctgaa
     2341 aagtttggca agtattttat cagtttttaa gcaagttttt taacttttgg tagatgattt
     2401 cgttttcctc taggctatag gaattagcac cacttgctag agggtggcct ccaccatcat
     2461 gttccttggc aatttcattg ataggatgga ttttactgcg taagcgaacg cggtagtggc
     2521 catcagcctg ttccacaaaa attccccaga gactaacact atcaatacgc ccaggtgcac
     2581 ttacaatggc tgcagtttca gcatcggtta cattgtattg tttcaagact tcttgactca
     2641 ggataacgcg agcagcacca ttttcatcca cttccagatg gtcgtagatg tagccttgca
     2701 gtttagcaat tttgtagctc atagtgtcca ttttgcgagt gagagccgca aagtcaaagt
     2761 tatgttctct caaataagca gccaggcgaa gagtccgtgc agtggtagaa gggtagagga
     2821 agcgacctgt atcaccgaca attcctgcaa agagcaactc agcatcgcga tctgccaagg
     2881 ctagttgggt tgtttgggca aatagggtaa tcatctcgct agcgctactt gaactagtat
     2941 cgacccaaga caggtcaccg tatacatcat catttggatg gtggtcaatc ttaatgagaa
     3001 aatcaccttg actatagcgt ttatcatcga tacgagcagt attagctgta tcacagacga
     3061 tgacaagtgc gccttggtag gccctatctt caacaagatc catctcagcc atccaagtaa
     3121 gagttggttc atcaaaaccg acggctttga tggttttttc tgggaaatga tgttccagca
     3181 aggctttcaa tcccacctga cttcccaagg catcagggtc tggtttcata tgacgatgaa
     3241 tgataatggt gtcgtattct ttaatttttt ctaaaatttg ttggcaaatc tccataaata
     3301 acctcaattc tttctcattt cattgtagca caagaatttt tatttttaaa atgaaaaaga
     3361 tgtgatataa tggagaaaga taaattgagg aggacgatat ggcattagca aaaattgtat
     3421 ttgccagtat gaccggtaat accgaagaaa ttgcagatat tgtagcagac aaattacgtg
     3481 acttgggctt ggatgttgat gttgatgaat gtacaactgt tgacgcttca gacttcttgg
     3541 aagcagacat cgctatcgtt gcgacctata cttatggtga tggtgaattg ccagatgaga
     3601 tgatggactt ctacgaagac ctagcagatc tcaacttgaa tggcaaaatc tacggagtgg
     3661 tcggctcagg agataccttc tacgatgaat tctgtaaggc tgttgatgac tttgaccgtg
     3721 tctttgtgtc aacaggagca gaaaaaggtt cagagtgtgt taaagttgat ctttctgccg
     3781 aggaagaaga tattgaacgc ttggaacaat tcgcagaaga attggttgct aaagtaggat
     3841 aagcataaaa gtgcgctgat gtaatcaatc agtgcatttt tcttatcgag agttgggatt
     3901 ttactagcct aattgatggc tttttgatac aataattcaa ataaaggagg agactgtatg
     3961 gatttagata ttattcgtca agaaatcgat caaatcgacg accaaattgt caaactgtta
     4021 gaagaacgaa tgcatttagt tgagggggtg gttgcttata agaaagcttc aggtaaaccg
     4081 attttagata ctaagagaga agaagttatt tttgaaaagg ttgggagtcg tgtagaggac
     4141 aagcgctatc aggagactat tgtagcgact ttttcggaca tactcaaacg ttcgcgtgat
     4201 tatcaggatc aaaatatcaa atgaaaaaag aacaatttta tccgctagga atttttctag
     4261 ctgctatgtt gggcggactt gtccgatatc tagtttccac ctggttacca gccagtccag
     4321 actttccttg gggcactctc tttgtcaact atctgggaat tttctgcttg atttatcttg
     4381 tcaagggcta tctggtctat aaggggacta gtaagggctt gattttagca ctggggacgg
     4441 gtttttgcgg aggtttaaca actttttcca gcctaatgct tgatactgtg aagctgcttg
     4501 atacagggcg ttatcttagt ttgatactgt atttgctttt gagtatcggt ggaggcctgc
     4561 ttttagctta ctatttgggg aggaagaaat ggtaatcgtc tatcttgcaa tcgcctgtgg
     4621 cttgggagca ctcgtacggt atttcttttc tcgctataat caagtttcta aattgccact
     4681 cggaacgctc atagctaatc ttttaggttg ttttttaatt ggagtattct acaatcatgt
     4741 agagtctaag gaagtatatg ctattctagc aacaggattt tgtggcggtt taacaacttt
     4801 ttcgaccttg aatgacgaac ttcaaagact gctaagtgat aagaaggtct tttattctta
     4861 cctgactttg acttacatag gtggtttggt tgcgattttt ttaggaattt tgctataaat
     4921 ttctttactt ttttttagaa atttggtaaa ctgtatcttg tgtgtaatgg acgcacaaaa
     4981 atacagttta tccgctgagg aagattcctc aagattgaca aagataggag aataaaatga
     5041 atccattaat ccaaagcttg actgaaggtc aacttcgtac agatatccca tcattccgtc
     5101 ctggtgatac tgttcgtgta cacgcgaaag ttgtcgaagg taaccgcgaa cgtatccaga
     5161 tttttgaagg tgttgttatc gcacgtaaag gtgctggaat ctcagaaaac tacacagttc
     5221 gtaaaatctc taacggtgta ggtgttgagc gtatcttccc aatccacact ccacgtgttg
     5281 aaaaaatcga agttgttcgt tacggtaaag tacgtcgtgc gaaattgtac tacttgcgtg
     5341 ctcttcaagg taaagcagct cgtatcaaag aaatccgtcg ttaattcgac taaaaaactc
     5401 tgcttttcag cagagttttt atctagctcc cttagttcaa tggatataac aactccctcc
     5461 taaggagtag ttgcaggttc gattcctgca gggggcagta attagatatc aaagaagttt
     5521 gtcaaaaagt ctttgatatt aaaagaacgc ataatatagg ggattgtctc cataatatta
     5581 tgcgttttat tattgaaaaa tttgggcaat catcagataa aattgagact atatcgagta
     5641 tataaatgtt tgtatagtca atttattcaa aatcgtcaag ttctaaatta tttaaaggac
     5701 tataacattc atatttcttt aagtaattgt ttatttcttc agcagtggaa cgaggtaaat
     5761 taactcttaa atagtcaata tcttccttag ataaaaaatg atttgcattc aaaattgaga
     5821 agcgaaataa tgcttcatca aaagcaaaat cataatcgtc atcagataat gattccatta
     5881 atgtttgaat atgttttagt gagtagtcag gtatcgaatc gggataatat actggataat
     5941 cagtggctga aaaattgttt tctaatcctg aaatagtaat tatcaaagat tctatgtaat
     6001 atattaaagc atgtttaata ttaccttctt gttccaaatg tcttccctga gcctttcgtg
     6061 tgttagataa gcatccaaaa tctcctgata cagtattcct atgagcttgt ttatttaaga
     6121 gactccattt tatatcacca aaagttgctt taaaagagat attgtttttt tctttacaat
     6181 aatcttccat acttatgtct ttatcatagt atgctttgat atagtcacta tgttcgataa
     6241 taagattttg tgcttctttt gttagtttaa attcgaacgg aatatctaat ttgtcaacgt
     6301 tgatattatt aattattctt gtaattaatt ctgctttttt tccagaagta gctaaattat
     6361 gtttagataa tatagttttt aattctacta ctttaagata tgataaagtc ttatttttag
     6421 tgaagtatcc taatttgtat aattgattgt gtgtagattc agggtcaatt tgaagagagt
     6481 atttaaaata tcttgggaaa ttataatttc tccctgtttt ttgagtccaa tctatgagta
     6541 tgagttgccc aggagtaagg ccgcactcta atttgtttag gtaaaaattg ttacaatcag
     6601 aatttgtgtc tctattatga ttattttgtt ttaaattaaa tagtttgcta aaaaaattca
     6661 ttggatttta ttgctaatca attcttattg aaaaatgata cttttacagt acccatgtac
     6721 ggatggcatg ggcaacgcca gattcatcat tagatttagt gatgtatttg gcgatttttt
     6781 tgatttctgg atttccattt tccatgacaa cagggttgcc aacgacttcc agcatggcac
     6841 ggtcattttc ttcgtctccg atagccatgg tttcatcttt ggttaatcct agtttttcag
     6901 ctaagtgagt aatagctgaa cccttgtcta cattcttttt aaggagttcg aggtagaaag
     6961 gagcagattt gttgatagag tagtgctcgt aaaattcggc tggtattttt tcaatcgcag
     7021 catcgagaat ttctggttca tcgataaaca tacatttaac aatttctttg ccagccattt
     7081 cttcaggggt acggtagaag ataggcatgc tgacgagggt tgattcgtgt acagtgtatg
     7141 ttccgatatt gcgatttgca gtatagatac cgtccttggt aatggcatgc atgtggacac
     7201 cgagcttgcg actgaggaat tccatatcca gataatcctc ataggtcaag gattcgctga
     7261 taatctcatg gccagtagca gtttcttgga caagggcacc attgaaggtc accacatagt
     7321 caccttggtc tctcaactgc aagtcgtcta gaagtttggc aacacctgcg atggggcggc
     7381 cagttgcaat cacgactttg acaccagctt ctttggcatc ttggatggca gaaaagactt
     7441 caggagtgat ttccttttgg ctgttgacaa gggttccgtc gatatcaacg gcaattagtt
     7501 taatactcat aaatttcctc ttctagtttt tatttggggt aaaatgatcg ttctcaatca
     7561 agtataaaag ttgctgggta atgctagcaa agatactgtt ttgatctaac atttctttcg
     7621 gaaaatagaa acgattatct ccgtgacgac taccagcaag ggattggacg ataggagaca
     7681 ggctagagag ttcggccagt tctccattct tttgtaaaat ctcaatctgt gtccgtggat
     7741 tttcagattc gggacgatag atatcataag ggaggtcaaa gttcttatga atggcagtat
     7801 agtagtcggg atcaaagcca atgtcctcaa ccaattttct catgctagcg agttggtctt
     7861 gatcttcttg tgaaaaggta atggatttaa agaccttgcg gttgacaaag cgttgcgata
     7921 aatctgcgag aattttgtca ggactggtca tccagagctg gaagtaggta ttcatcacac
     7981 catcatctag agccagatag tcagacaagg tcacattttt ttcaaagaaa ggcaggaggt
     8041 gtggggaagt tcgtgcaaag aagtctttgt ccttagggta gagttcctta gcgcgcttga
     8101 gaagattctg taggagaact tccatagcgc gtgttgctgg gtggaaatag acctgcatat
     8161 acatctggta gcgactgagg acatagtctt cgatggcgtg catgccattg cgctgaaagg
     8221 cgataccatt ttcgatagga cgaatgactc ggaggattcg agtcaggtca aattccccat
     8281 aggatgctcc tgtaaaatag gagtcacgca agagatagtc catgcgatct gcgtcaatct
     8341 gactagaaat gagttgtacg acctgcttgt taggataggt atggtctatg acactggcaa
     8401 ctttctctgg aaaatcgggc gctacttgta gcaagacttg gtgaatctct gtctcaggac
     8461 tttgaataat ctcctgagta atagcttcat ggtctgtatc aaagagatgt tcaaaagtat
     8521 gggagtaggc gccatgccca aggtcatgta ggagagcagc gatcatggtc aagagagact
     8581 cggcaggatt ccattcctca ggatattttt cttcgaaaat ctctgtgatg cgtcgtgcaa
     8641 tttcatagac tcctagacag tgagagaagc gactgtgttc tccaccgtgg aaggtataac
     8701 tggaagttcc cagttgtttg atccggcgca aacgctgaaa ttcttttgta ttaatcaagt
     8761 catagatgat ttgattaatg acatggatgt agttgtgaac tgggtcacgg aatacttttt
     8821 cgttcatatg accattatag caaaatcctg ctctttttgg taaaatagta ggacaagaga
     8881 caagaaagag ggcctgatgt gaagattcgg atgcgaaata caattcagtt tgatgagcag
     8941 ttggaagtga ttgaccagct ttatgatgtg gaagtgcatg aaaaaggaga ttatagctac
     9001 ctgcttttct ataatgagga aaaggaaaaa gtagtgatta aatttcatgg tcaagaactt
     9061 gtgatgagcc gattttctaa tcccaagacc attatgcgct ttctaaagaa tagcgatagt
     9121 ttagcctata ttcctacacc tatgggcatg caggagttta tcatccaaac gagccattat
     9181 caagttgata ggcaaaagat tgaactagat tatcaactac aaaatcaaga gggacatcct
     9241 tttgccagct atcaattgga aattacttgg ggctaggctc atgtcttttt caaatttagc
     9301 tatctatctt cttggatcgg tttcctagtg tggtagatta ggctaatttt tggtataata
     9361 aaagttatgg aaatcgaaaa aaccaatcgt atgaatgcgc tctttgaatt ttatgcggcg
     9421 cttttgacag ataagcaaat gaattatatc gagctctact acgctgatga ttacagcctt
     9481 gctgaaattg ccgaggagtt cggtgtcagt cgtcaggctg tctatgacaa tatcaagcga
     9541 acagaaaaga ttctggaaga ttatgagatg aaattgcaca tgtactcgga ctatattgtc
     9601 cgcagtcaga tttttgatca gattttggag cgctatccca aggataactt tctgcaggag
     9661 cagatagaaa ttttaacaag cattgataat agagaataag aggaagaaaa atggcatttg
     9721 aaagtttaac agaacgtttg cagaacgtct ttaaaaatct acgtaaaaaa ggaaaaatct
     9781 ctgaatctga tgtccaagag gcaaccaaag aaattcgctt ggccttgctc gaggccgacg
     9841 ttgccttgcc tgttgtaaag gactttatca agaaagttcg tgagcgtgca gtcgggcatg
     9901 aggtcattga tacacttaat cctgcgcaac agattattaa aatcgttgat gaggaactga
     9961 cagccgtttt aggttctgat acggcagaaa ttatcaagtc acctaagatt ccaaccatca
    10021 tcatgatggt tggtttacaa ggggctggta aaacaacctt tgctggtaaa ttggccaaca
    10081 aactcaagaa agaagaaaat gctcgtcctt tgatgattgc ggcggatatt tatcgtccag
    10141 ctgccattga ccagcttaag accttgggac aacagattga tgtgcctgtc tttgcacttg
    10201 gaacagaagt accagctgtt gagattgtac gtcaaggttt ggagcaagcc caaactaatc
    10261 ataacgacta tgtcttgatt gatactgcgg gtcgtttgca gattgatgag ctcctcatga
    10321 atgagcttcg tgatgtgaaa gcattggctc aaccaaatga aatcttgctt gtcgttgatg
    10381 ctatgattgg tcaggaagca gccaatgttg cgcgtgagtt taatgctcag ttggaagtga
    10441 ctggggtcat ccttaccaag attgatggcg atactcgtgg tggtgctgct ctgtctgttc
    10501 gtcacattac tggaaaacca atcaagttca ctggtacagg tgaaaagatt acggacattg
    10561 aaaccttcca cccagaccgc atgtctagcc gtatccttgg tatgggggat atgctcactt
    10621 tgattgagaa agcttctcag gaatacgatg aacaaaaagc ccttgaaatg gctgagaaga
    10681 tgcgcgaaaa cacctttgat tttaatgatt tcatcgatca attagatcag gtgcaaaata
    10741 tggggccgat ggaagacttg ctcaagatga ttccaggtat ggccaacaat ccagcccttc
    10801 aaaacatgaa ggtggatgaa cgccagattg ctcgtaaacg tgccattgtg tcttcgatga
    10861 cacctgaaga gcgtgaaaac ccaaatttgt taaatccaag ccgtcgccgt cgtattgctg
    10921 ctggttctgg aaatacattc gtcgaagtca ataaattcat caaggacttt aaccaggcta
    10981 aacagctcat gcagggtgtt atgtctgggg atatgaataa aatgatgaag caaatgggga
    11041 ttaatccaaa taaccttcct aaaaatatgc caaatatggg aggaatggat atgtctgccc
    11101 ttgaaggaat gatgggacaa ggcggtatgc ctgacttatc agctctcgga ggagcaggaa
    11161 tgccagatat gagccagatg tttggtggcg gtttgaaagg taaaattggt gaatttgcca
    11221 tgaaacagtc catgaaacgt atggctaaca aaatgaagaa agcgaagaag aaacgcaagt
    11281 aagacaagag attgatgcaa atctcatttg atgagaaaat aaagtaaaaa tttctatgat
    11341 aaaacgtata gtatcaaggt tttagaatat ctgatattat acgttttttg attttaataa
    11401 ttttgttaag acacttttat tatggtatgc gaaaaatcca ctcagctgtc tgagtggatt
    11461 aggtgtattt agactcttag tctttatttt cgtatggcaa gatcaagttc aagatgattc
    11521 ctgtcatggc tgaaagggca gtacctgaaa gtgtaactgg accaagttta aggatagctc
    11581 ctccaagtcc aagaaccaac atagcacttg cgatgatgag gtttcgcatt tgagcgaaat
    11641 caacacgttc tttaatcaag actttcaaac cattgctggc gataacccca tagagaagga
    11701 ttgacatacc accaagtaca gcgtttggaa tagttgaaat caaggcagtg aatttaccaa
    11761 ggaagctgag ggcaatcgcg atgaaggcag cgttacggat aactgagaca gaagcgatac
    11821 gagtcatacc gataacccct gtattttctc cgtaagttgt attggctggt ccaccaagga
    11881 aggcagaaac agaagttgcg ataccgtcac caagaagagt acggtgaaga cctggttctt
    11941 ttaagaattg acgaccacag atttgaccca aaacagtatg gtctccgata tgttcagaaa
    12001 ttgttacgat agcgattggc aagatagcga tggcttctgg accaaagtaa agattgtact
    12061 ctttaaaggc accacctgtg ctaaatggca agtagaaacc aggaatttcg aaccagttgg
    12121 ctttaagaac tggtgtaaag tcaaccaagc caagagttag tgcgaaaagg taaccaccga
    12181 taatggcaaa gaggaatgga atgattcgta ggaagccttt tccttttgta ttgataaagg
    12241 cagcaattag gaaagtaaca acggctacca gagcattttt ccaatttccg tctgctacaa
    12301 gacctgcatt ggtaacagct gaacctgcaa gtccaagacc gataacgatg atcataggac
    12361 cgataatgat tggtggcaag agtttatcaa tccattttgt tcctacaaat cggatgctgg
    12421 tagcaacaag gacatagacc aaaccagtca agataacccc tgtttgggca gcagatacat
    12481 ccccccccat ttctttcata gccagtgaca tagctgtgat aaaggcaaat gaagaaccta
    12541 gataaactgg aactttaaaa ccagtagcaa tcatgtagat gagtgttcca acacctgaag
    12601 caaaaagggc aacagataca ggcattccca aaatcaatgg taccaagatg gtcgcaccaa
    12661 acatggcgaa aacgtgttgg aagctaagga gaattccttt tccatccgaa ggacgttggt
    12721 caacgtctag taacaaatca acagttgatt cttgtttcat ataaacctca cttttgggca
    12781 tcagaaaaga gcccattatt ttacagcaat aggccctcag agtaagactt ctctaaaatc
    12841 tagactttaa agagtttcaa atatttttgc gtcttcgtca cctcacggga tgacattaaa
    12901 aacctttgct taggatagta tagcagaaaa aaatgatttt gtaaatcatt ttttcccgag
    12961 cctagaaata aaagagcgag gctgattttg taaacatttg tttactaaaa aatttaaagt
    13021 gggcgtttat ttggcatacc agccttacgt ggatatttat ttggtgtttc ttttttcttt
    13081 tctaccactg tgatatagcg cggatctcta ttcggtaggg cgtagctgag attgtcttcg
    13141 accttactaa aaaggagatt gagggcattc ttagcttcta ataattcctc aggcgcattg
    13201 ctggccttga gtgccaatag tttgccacca accttaaggt agggaatagt caattcagat
    13261 aggacctgca tacgggcaac cgcacgagct gttacaaaat catattgagc acggaagttc
    13321 ttgtcttggg caaaatcttc ggcacgtccg tggtagaaat gaactccgtt caaatccagt
    13381 tcttgagcca agagttgtag gaagttgatg cgcttattga gtgaatcaat aatggtcaca
    13441 tctaactccg gatagagaat tttcattggt agactaggaa atcctgcccc agccccgata
    13501 tcaagaagtt tgatagtttc attgggaatc aaaccttgaa gaatgggtgc aatcgaatcg
    13561 taaaaatgtt tgagataaac ttcttccttg tccgtaatcg ccgtcaaatt aatcttctca
    13621 ttccactcga ccaagagctc aaaataacgt tcaaattgtt ctttttgctg gttcgaaagt
    13681 ggaagattct gctcggcaag caagttgtaa aatgtttctg gtttcatagt tatttccttc
    13741 tttagtatca tcttatttta ccacaatcat agaaaatttg atatactggt actaatctaa
    13801 aagcagaaag gacttatatt atgacttgga ttattcttgg agttatcgct cttattgtta
    13861 tttttgtgat tgttagctat aacggtttgg ttaaaaatcg tatgcaaacc aaggaggctt
    13921 ggagtcagat tgatgttcag ttgaaacgtc gaaatgacct cttgccgaac ttgattgaga
    13981 ctgtaaaagg ttatgccaaa tatgaaggtt ctacccttga aaaggtggca gaactacgta
    14041 accaagtggc ggcagcgact tcaccagcag aagctatgaa agccagtgat gccctcactc
    14101 gtcaggtttc aggtattttt gcagttgcag aaagctatcc agatttgaaa gctagtgcta
    14161 actttgttaa attgcaagag gagttgacaa acacagaaaa taaaatttct tactctcgtc
    14221 aactctataa cagtgttgtc agcaactaca atgtaaaatt agaaactttc ccgagcaata
    14281 ttatcgctgg aatgtttgga tttaaagcgg cagatttcct tcaaacacct gaagaggaaa
    14341 agtcggttcc taaagttgat tttagcggtt taggtgacta agatgttgtt tgatcaaatt
    14401 gcaagcaata aacgaaaaac ctggattttg ttgctggtat ttttcctact cttagctctt
    14461 gttggttatg cggttggtta tctctttata agatctggac ttggtggttt ggttatcgca
    14521 ctgattatcg gctttatcta cgctttgtct atgatttttc aatcgacaga gattgtcatg
    14581 tccatgaatg gagcgcgtga ggtggatgag caaacggcac cagacctcta ccatgtagtg
    14641 gaagatatgg ctctggtcgc tcagattcct atgccccgtg ttttcatcat tgatgatcca
    14701 gccttaaatg cctttgcgac aggttctaat cctcaaaatg cggctgttgc tgcgacttca
    14761 ggtctactag ctatcatgaa tcgtgaagaa ctagaagctg ttatgggaca tgaagtcagt
    14821 catattcgta attatgatat ccgtatttcg actattgcag ttgcccttgc tagtgctatc
    14881 accatgcttt ctggtatggc aggtcgtatg atgtggtggg gtggagcagg tcgcagacga
    14941 agtgatgatg accgagatgg aaatggtctt gaaatcatta tgctagtggt ttccctacta
    15001 gctattgtac tggcacctct cgctgcaacc ttggttcagc tcgctatttc tcgtcagagg
    15061 gaatttctgg cagatgcatc tagtgttgag ctgactcgca atccccaggg aatgattaat
    15121 gccctagata agttggacaa tagcaaaccg atgagtcgcc acgtcgatga tgctagcagt
    15181 gctctttata tcaatgatcc caagaaaggt gggggggtcc aaaaactctt ttatacccac
    15241 ccacctatct cagaacggat tgaacgttta aaacagatgt aaaagaatcc agaggtcgtc
    15301 tctggatttt tgctatgttg caaatttata aatcttctaa attaactaac tccaaaccgt
    15361 gttctgtcat gcgatagatg atcgagcaga cttcttttaa gaaacgacgg tcatgcgaaa
    15421 cagtgatgag accgcctgga taggttgcaa agagttttct gatttggggt tgagaagtgg
    15481 gagaaaagtt tcgtgtgggt tcatccagca ggagaaagtt tggtttgcgc aggactagat
    15541 ccaaaagcag gagttttccc tgttgtccgc cagataagga gcgaatttga tgctgcattt
    15601 ctggataact gaaattgaga ctggctaggt gagagtggat tttctgaagt tcctcttttt
    15661 ccccagtttt gctgatataa gctattggtg ataaatccaa ttgtagtttt ttgtggtaat
    15721 cttgtggcat aaaaccaagg gaaatctctc ttttatcatt cagaagttgc tttaatttgg
    15781 ctaacagagt tgatttccca acaccatttg gcccgataat accgattttt tcttgcccac
    15841 ggacagttag ttgtagtttt tgaaccaaaa ctcggtcgtc aatggacaaa ttttcttttt
    15901 ccagttggac taagacttta gaagctggta atggttggat gtctgaaaag aaaagttgga
    15961 tttgttcctc ttcaagtggt ttttgagtca tggactgagc tgccttttcg tagcgttttt
    16021 cttgtgagag gacagttttc atctttttag ccaataggcg accggcagta ctatctttgg
    16081 tagctcgaag cgcagtttct acattttgct taactctccg atgtttttcc atggttttat
    16141 cgtaggctct ttggttgtta gcagcttgct gactttgttt ggcaaaatta gcctttctct
    16201 gctcactata gctatcatag tctaaatgct ctactagcgt ttccgcttct ttacggtgtt
    16261 tgaccagtcg caagtgaaca atagtgtctg ccgtttcaga aagaaagtct tcatcatggg
    16321 aaatgaaaat aacggtttgc ctggtctttt gaatctggcc ttttagccaa tcaactgtct
    16381 caaggtctag gtcatttgaa ggttcatcta aaaatagaat ctcaaagggt ttggctaact
    16441 catggataag ctgaattttc aaagcttctc cccctgatag attgccaatc tcttggtcac
    16501 ttgcgaaacg attgctatca aaatgcaatt cctccgccaa acgatagagg atactgtagt
    16561 ctaaatcaat agaatctaaa aagaagtagt cgtgtaaagt tttctttttc agctcctcgg
    16621 gaagtttttg aggaatgtag gccagtgact gatagtcaga ttggatgttt cccttgatag
    16681 tgaaatcaga caaagcttcc cccattaaag ttttaagtaa ggttgattta ccatttcctt
    16741 cttcgccaat aatagctacc ttttccccgt cttgtatggt catgcttagg tcagagacaa
    16801 ggtctcgtaa atctttgttt tgtgtgatgg tcaggtgatt gatttttatc atactattgc
    16861 cctttctaga atgttcatag tgcataacaa aaagctctac tttacctagt agagcccaaa
    16921 gtctatgtca aaaaaactct attaacatgc cagaaaaagg gcataaaaga gcacacaaaa
    16981 agagacaaaa acaagatcta ctaaataaag gttctttatt tgatagactt agttgttcat
    17041 gtctccctta cctcctagta ttagtatctt tatactatac ttttaaggaa attttgtcaa
    17101 cagaaaactg gaaattctat gctctaaaat ccaaaaacag gtctatagag acttagtacg
    17161 tgtttgacat gctcgtaatg gattttatca tagtttcgcc aagcagtgcg ttcttgattg
    17221 tttagtttta ggctacccag tccaatcata ggactggtgg gttggtaaaa tttctcaaga
    17281 tcaattaaga tactgttgtt caacttttcc gttttttgag ttcttgcata gtagtgttta
    17341 gcagctcttg tagtcgaata tcatctgccg taccctgttt acagttttgg tagcttttat
    17401 ttaacttgga taggagttga atgagtttct tgtcttccgt gtgagcatcc tccttgatct
    17461 gatgtactct ttccctatag tatagcacta aaaaataaaa ctgtcatagt gaatatgtta
    17521 aaatttcgaa ttttaattac aaagtttggt gtgctgattt gtagcctttt catggtataa
    17581 tcaagagagt aaatctttat ggaggaagta tgaaattaaa tattcaagaa attcgtaagc
    17641 agtctgaagg tttgaacttt gaacaaacgt tagatttagt tgatgacctg cgtgcacgta
    17701 atcaagaaat tttagatgta aaagatatcc ttgcagttgg gaaagtacaa tatgaagacc
    17761 gtatgtattt cttagattat caactatctt ataccattgt tcttgcttcg agtcgcagta
    17821 tggagccagt tgagttagtt gaatcttatc cagtcacgga agttttcatg gaaggcgcaa
    17881 ctaaccagct agatcaagaa gttttagatg atgacttggt cttgcccatc gaaaatgggg
    17941 agcttgacct tgctgagagt gtatcagaca atatcctgct aaacattcct atcaaggtct
    18001 tgacggctga agaagaagct ggtcaaggat ttgtctcagg aaatgactgg caaatcatga
    18061 cagaggaaga ataccaagct caacaagcag taaagaaaga agaaaacagt ccttttgctg
    18121 gcttacaagg actatttgac ggagatgaat aatggtcttg tcaaaaaaac gagcacgaaa
    18181 ggtgctagaa gaaatcattg ccctcttccc agatgccaag cctagtcttg attttaccaa
    18241 tcattttgaa ctcctggttg cggtcatgtt atcagcccag acgacagatg cagcggtaaa
    18301 taaggccaca ccaggtctct ttgttgcctt tccaacaccc caagctatgt ctgtagcgac
    18361 agagagtgag attgcttcac atatttctcg cttgggattg tatcggaata aagctaaatt
    18421 ccttaaaaaa tgtgcccaac agttactaga cgattttgat ggtcaagtcc ctcagacacg
    18481 tgaagaattg gagagtttgg caggtgttgg tcgcaagaca gccaatgttg tcatgagtgt
    18541 aggatttggg attccagcct ttgcagtgga tactcatgtg gagcgtattt gcaaacacca
    18601 cgatattgtc aaaaaatcag cgacgccact tgaggtggaa aagcgggtca tggatatctt
    18661 gccgcctgag cagtggttag ctgcccatca ggccatgatt tattttggaa gagccatttg
    18721 ccatccaaaa aatccagagt gtgaccagta cccacaatta tatgatttta gcaatttgta
    18781 agatgctaca ttgaaacttt ttgcttgatt ttaagcatgc tttgtgctat agtaaatgat
    18841 aactaaatat tcctttaaac ctgtcccgtg aggcaggcaa ggagcgcgat aaagtagaag
    18901 ggtgaagtct atactgtgtg cagtagggct cgcttggcta taaatttcaa gtctccttgt
    18961 ttaaggagac ttttcttttt ggaggtttgt catgaaaaca aaagaagttg tagacgaatt
    19021 gaccgtcaaa cgagcgatta cgcgtattac ttatgagatt atcgaacgca acaaagattt
    19081 gaataagatt gtcttggctg gtattaaaac tcgtggtgtc tttattgccc accgaatcca
    19141 agaacgtttg aagcagttag aaaatctttc agttcctgtt gtggaattgg atactaaacc
    19201 tttccgtgat gatgttaaaa gtggagaaga tacttctttg gtttctgtcg atgtgacaga
    19261 ccgcgaagtt atcttggtgg atgatgtgct ctatacaggt cgtaccatcc gtgctgctat
    19321 tgataatatt gtcggtcatg gtcgtcctgc gcgtgtgagt ttagcagttc tagtcgatcg
    19381 tggacataga gaattgccaa tccgtccaga ttacgttgga aaaaatatcc caaccagtcg
    19441 ttctgaagaa atcatcgtag agatgacaga acttgatgac caagacagag ttctgattac
    19501 tgaagaagct tagaaagtta aaggagtagc catgtcagaa aatcaacaag cattgaacca
    19561 tgtggtgtcc atggaagacc tcactgtcga tcaagtaatg aaattgatca agcgaggaat
    19621 tgagtttaaa aatggagccc agcttcccta tgaagaccat ccgattgttt ccaatctctt
    19681 ctttgaggat tctacacgga cacataagtc ctttgaagtc gcagagatta aacttggatt
    19741 ggaacgactt gactttgatg tgaagactag ttcggttaat aagggtgaga cactttatga
    19801 caccattttg actctgtctg ctttaggagt ggatgtctgt gtgattcgcc atccagaggt
    19861 cgactactat agagaattga ttgctagtcc aacgattacg acttccatca tcaatggtgg
    19921 agatggttcg ggccaacacc ctagccagag cttgcttgat ttgatgacca tttatgagga
    19981 atttggccac tttgagggtc ttaaagttgc tattgcaggt gacttggacc actcacgcgt
    20041 tgccaaatcc aatatgcaga ttttgaaacg cttgggatct gaactctttt tcgctggacc
    20101 tgaggaatgg agaagtcaag agtttgcaga ctatggacag tttgtaacca ttgatgaaat
    20161 cattgatcag gttgatgtca tgatgtttct ccgtgtgcaa cacgaacgcc atgatagtgg
    20221 agctgtattt tcaaaagaag actaccatgc ccaacatggc ttgactcaag aacgttacga
    20281 tcgtttgaaa gaaacagcaa tcctcatgca cccagctcca atcaatcgtg atgtagaaat
    20341 agcagaccac ttggttgaag caccaaaatc acggattgtc caacaaatga ccaatggtgt
    20401 ctttgttcga atggcaatct tagaatccgt actagcgagt agaaacgcca actaaaacac
    20461 aagacgttaa aagacgccag tgagcgtcca cgagaggtga aaatatgaca aaaagaattc
    20521 tagtattaga agatggcaca gtttttgaag gcaaggcctt cggagcagat attgatgtaa
    20581 caggcgaaat cgtctttaat acagggatga ccggctacca agaatccatt acagaccagt
    20641 cttataatgg acaaatcttg acctttactt atcctttggt cggaaactat ggaattaacc
    20701 gtgatgatta cgaatctatt attccaactt gtaagggagt tgttgttttc gaagaagcgc
    20761 gtagagcaag caactggcgc aaccaaatga ccttggatga atttttgaaa gccaagaaaa
    20821 ttcctggtat ttcagggatt gatacgcgtg cacttaccaa gattattcgt aagcatggta
    20881 ctatgcgagc aaccttgact catgttggag atagtatgga ccatgtgact gaccagctcc
    20941 aagcaacagt attgccgaca gataatatta agcaggtttc tactaaaact tcctatccag
    21001 ctccaggagt tggtttgagc gtggtgttag tagactttgg tctcaagcac tcaatcctac
    21061 gtgaactttc taagcgcaac tgtaatgtga cggttgttcc ttattcgaca acggctgaag
    21121 aaattctcca tctcaatcct gacggagtga tgttgtcaaa cggtccaggt aacccagaag
    21181 atgttccaca ggcactggat atgattcgcg gtgtacaagg aaaaattcca atctttggta
    21241 tctgtatggg acatcaactc tttgctatgg caaacggggc taagacctat aagatgaagt
    21301 ttggccaccg tggattcaac catgcggtac gtgaaatcgc aacaggacga gtagacttca
    21361 ccagccagaa ccatggttat gcagtcagcc gcgaggattt gccagagcac ttgattatta
    21421 cccacgaaga aatcaatgac aagtcagtgg aaggtgtgcg ccacagatac caacctgctt
    21481 tctctgttca ataccaccca gatgcagctc ctgggccaca cgacgctagc tacctatttg
    21541 acgagtttat cgagatgatg gaagttttta aacaatcaaa ctaagaacga gtaaaagctc
    21601 gtcggagaat ttatgtaact gaacacggac ggaaagctca gaatttagag aaaccaactt
    21661 ggattgtcaa tccttccttg atttcttaaa attcaatcgc tttctattcg tcctttgtat
    21721 cttatttaat gtcgccctga gaggcgacga atagaaagga gaagggtgct ccgtatttgc
    21781 tgaactgaat acgggctacg gacggtgcta aaaagatagt tattcctaga actgacagtt
    21841 cttcgtcata actcctattt tagctttgtc cgcttgacgc ccttaatatc ttatatatgc
    21901 ctaaacgtac tgatattcaa aaaattatgg tgattggttc tggtccgatt attattggtc
    21961 aggctgctga gtttgactat gctgggaccc aggcttgctt gtcgttgaaa gaggaaggtt
    22021 atgaggttgt tttggttaac tcaaatcctg caaccatcat gacggacaag gaaattgctg
    22081 acaaggttta cattgaaccg attacacttg agtttgtgac acgtattctt cgtaaggaac
    22141 gtccagatgc cttgctacca acactcggtg gtcagacagg tctcaacatg gccatggaat
    22201 tgtctaaaaa tggtatctta gatgagctta gcgttgaact tctgggtact aaattgtctg
    22261 ccattgacca agcggaggac cgtgacctct ttaaacaatt gatggaagag cttgagcaac
    22321 ccattccaga atctgaaatt gttaacacag tagaagaagc agttgccttt gcagcgacaa
    22381 ttggctaccc agtcatcgtt cgtccagcct ttacccttgg tggtactggt ggtggtatgt
    22441 gtgccaacga gaaagaattg cgtgaaatca ctgaaaatgg tttgaaattg tcacctgtta
    22501 cccaatgttt gattgagcgt tcgattgctg gtttcaagga aattgaatac gaagtgatgc
    22561 gtgactcagc tgacaatgcc ttggttgttt gtaacatgga aaactttgac ccagttggga
    22621 ttcacacggg ggattccatt gtatttgccc ctgcgcaaac catgtcagac tatgaaaacc
    22681 aaatgcttcg tgatgcgagc ttgagcatta ttcgtgccct caagattgaa ggtggatgta
    22741 atgttcagct agctcttgat cctaacagct tcaagtatta tgttatcgaa gtaaaccctc
    22801 gtgtatcacg ttcgtcagcc cttgcttcta aagcgacagg atatccgatt gctaagttgg
    22861 ctgccaagat tgcagtaggt ttgaccttgg atgaggttat aaacccagtt acaggttcaa
    22921 cctatgccat gtttgaacca gcccttgact acgtagttgc taagattcca cgtttcccat
    22981 ttgacaagtt tgaaaagggt gaacgccgtc tcggtacaca aatgaaggcg actggagaag
    23041 tcatggcaat cggtcgtaac atcgaggaat ctcttctcaa ggcctgccgc tcccttgaaa
    23101 ttggggtgca ccacaatgaa atacctgaac ttgcagcagt ttctgatgat gccttgattg
    23161 aaaaggttgt caaagcccaa gatgaccgtc tcttctacgt atcagaagca attcgtcgtg
    23221 gctacacacc tgaagaaatt gcagagctta caaaaattga tatcttctat cttgataaac
    23281 tcttgcatat ctttgaaatt gagcaagaat tgggtgctca tccacaagat ctagaagttt
    23341 tgaaaacagc caaacttaat ggtttttcag accgtaagat tgctgaactc tggggaacga
    23401 ctgatgataa agttcgccaa cttcgcttgg aaaacaagat tgttccagtt tataagatgg
    23461 tagacacttg tgcggcagag ttcgactccg aaacgccata tttctattca acctatggtt
    23521 gggaaaatga atctatcaga tctgataaag aatctgtact tgtcctaggt tcaggtccaa
    23581 tccgtatcgg tcaaggggtt gagtttgact acgcaaccgt tcactctgtt aaggctatcc
    23641 aggcagctgg ttatgaagct atcatcatga actcaaaccc agagaccgtt tcaacagact
    23701 tctctgtatc agataagctt tactttgagc cattgacatt cgaagatgtt atgaacgtca
    23761 ttgacttgga acaaccaaag ggagttatcg ttcagttcgg tggtcaaaca gccatcaacc
    23821 ttgcggagcc attggcaaaa gcaggtgtga ccatccttgg tacacaggtt gctgacctag
    23881 accgtgccga agaccgtgac ctcttcgagc aagctctcaa agaattggat attccacagc
    23941 caccaggaca aacggctacc aatgaagaag aagcagctct tgcagctcgt aagattggct
    24001 tcccagttct tgtccgccca tcttatgtac ttggtggacg tgccatggaa atcgttgaaa
    24061 acgaagaaga ccttcgttct tacatgcgaa ctgctgttaa ggctagtcca gatcacccag
    24121 ttcttgtcga ctcttatatc gttgggcaag agtgcgaagt tgatgccatt tcagatggta
    24181 aagatgtgct cattcctggt atcatggagc atatcgaacg tgctggtgtc cactcaggtg
    24241 actcaatggc tgtttaccca ccacaaacct tgtcgcaaaa ggttcaggag accatcgcag
    24301 actacaccaa acgcttagca atcggtcttc actgccttgg aatgatgaac atccagtttg
    24361 ttatcaagga tgaaaaagtc tacgttattg aggtcaatcc acgtgccagc cgtactgttc
    24421 cattcctatc taaggtaacc aatattccta tggctcaagt agcgaccaag ctcattcttg
    24481 gtcaaagttt atcagaactt ggctaccaaa atggacttta ccctgaaagc acccgtgttc
    24541 atatcaaggc acctgtcttc tcctttacca aactagctaa ggtagacagc ttgctcggtc
    24601 ctgaaatgaa gtcaacaggt gaagttatgg gttctgatgc tactttggaa aaagctctct
    24661 ataaagcctt tgaagcttct tatctacact tgccaacttt tggtaatgtc gtctttacca
    24721 tcgctgatga tgccaaagaa gaagccttga acttggctcg tcgtttccaa aacattggtt
    24781 atggaatcct tgcgacagaa gggacagcag ccttctttgc tagtcatggc ttgcaagccc
    24841 aacctgttgg taagattggt gatgacgata aggatatccc aagttttgta cgcaaaggaa
    24901 gaattcaagc tatcattaac acagtaggaa caaaacgaac tgctgacgaa gatggtgagc
    24961 aaattcgtcg ttcagccatt gaacacgggg tgcccctctt cacagcgcta gatacagcta
    25021 atgccatgct taaggtactt gaaagtcgta gctttgttac agaagcgatt taaatagaaa
    25081 aataagatat agcagactga atttagaaca gtacacagga atactaaaat atttctataa
    25141 attaatttga attttctaat tgatttgttc gcatcttatt tcaatctact atagaaaaaa
    25201 gtctttaaaa ttataaaacg catcatatca aggtttttca aaaaccttga tatgatgcgt
    25261 tttattgtgg gaatatgtat ttcattttct actaaaatta tgtttttgaa taacctctat
    25321 cttagtagtt tgtataatcc ccctcaatca gtttttgcga taagctttaa tgctatgact
    25381 ataccactct tgcatttctt ttgatggtgg tgtcatataa tcgccataca tctgggttaa
    25441 aaattggtca tattttttgg gaacaggcaa catacggccc tcaaactcag ttaaaatcag
    25501 ttctttaaag gtatcaactg ggaagatttc tttcatccct tccttaccga tcccaactcc
    25561 tccttcatat tgaggaatgt tggttacagc atttttgact agttgatcaa ttttcttgta
    25621 aaagtagcga ggattgacaa atcggagagc gtaccagcta cataatctaa gaaaatcttt
    25681 tagtttgcta tcaccgtgaa ctgctcgtga ttttttgata taagctagtt gacgaagagc
    25741 cacatactta tagctcttgt cgacaatgct caagtctgta aatcgatcaa ttgggaagac
    25801 atcgatgaaa aggctggtat catgacgctt gtacttaaca tggtcttcta taacagtaga
    25861 agtgtccaaa atcgatgcga aattatggaa gtaccaagaa gatgtatcgt aggaaagaac
    25921 cttgtagcga gggtgatttt cttcttcaat aatcttcagt aaacgctcat aatcctcacg
    25981 ataaagggaa atatcaatat catcatccca aggaatcata cctttgtggc ggatggctcc
    26041 aagcatggtt ccataactga gaaaataagg aatatcatgt ttcttacaag tctcatcaat
    26101 atagtccagc agggctagtt gaatttcttt aatttctttt ttttctaaat attgcatcct
    26161 aatcctccaa tttataagcg tgaaattcat gactgtagaa gcgtttttct tctggtggta
    26221 gggtcatata atctccataa aattgtgtca aaatagtatc aaatttttca ggtgcaggaa
    26281 ggcttaaatt ctcaaagggt aaatcgattg ttttatcaaa ggtaccactt gggaagactt
    26341 ccttttcctt aaattttgaa gggataaaag ccatatactg cccattttca cgactatatt
    26401 tttgaatttc tttctcgatt ttatttgcaa aataacgagg agaaactggt cgaaggagca
    26461 accaaaaggc tgttcgtatc caatctttta aaaggctatc cttatagaca atatttttat
    26521 gtttactgaa agacagcagt ttgaagcttt ccagtttata acaagtatca atgaccttag
    26581 gatcatcaaa gcgatctata gggaaaatat cgataaagat accagactca taggtttttg
    26641 tatttcgagt atcaataatt ttagtcgtac tgtcggttat cttgataaag ttgttaaagt
    26701 agttcttatc agtttctaag gataggagct tatacttgct tttttccttt tgaaaaatgt
    26761 taataaatcg ttggtagtct tctctaggca tggataaatc aatatcgtcg tcccaaggga
    26821 taaagccctc atgtcgaacc gccccaatca gagtaccgta gttaataata tagttgatat
    26881 tgtgcttttt acagagagta tcaatataat ccaaaatttc taattcaatt tgtttggcat
    26941 cttcaatggt tagttgtttc attttaaact cctatgattt tttgaattta ttttttaagg
    27001 ctaggacatg gtttaaaaat tcatagaaaa tgctatcttt tgtgaagaca agtagactaa
    27061 tataagagat agctgatagc aagacaatca aaccagtatt aattaaaaat ggcaaattaa
    27121 tgaccatatc cacaggatac acgaaattaa tcaggaaata aattgctaca aaggaaagtg
    27181 aaaagagaga gtatcgaaca gtatagctaa agatatgtcc caagtggatg agttgttttc
    27241 tatggatgaa aataatatag aaaacaagta gagaagtctc tgataacata gttgtcagta
    27301 agtagtattc aggaaccacg atatggttga aaaagaggag actattcaag cccaaattga
    27361 gtagcccagc aaagactgta tagactgtga tacgtttttc atagccattg gtaaagagaa
    27421 tttgggaacc aagaatggta tctaaggcca ggataatcgt acgaaaagcg aagagagagg
    27481 tcaagatgcc gcctccgata tatttttcac taccgtaaag taggatggca tttggtccta
    27541 aaaccatgag tccaaaactc agtggaatga taaagaagtt aaagattcga ctacctctat
    27601 taaccagaga aacataggct tctttgtctc ctttccccag atagtaactg agacgaggca
    27661 cactcactcc aattgcacct gttacaaccc cagctataac ggtcacaatt cgctgagcta
    27721 tggtatagta actaacgttg acatcaatcc ctgttttaac gaggaagagg cgatctaaaa
    27781 aagtgaagag catattggca ttggcaaaga ctaacatggc tgtcagaggg agaaagagtg
    27841 gtttaaaatc acttaggtga atcttaacaa gtttgatgtc tcttttaatc caaaaataac
    27901 taatcaggta gttaatcagc gtcgataaac tcatcacaag tgtatagaca acaatatcgt
    27961 gttcattttt aacaaataag aaaatagaga ccagcatcag gatacggatg aaggcagttt
    28021 tgtaaaagag aaaactgtaa ttttccagag cttcattgac ccattcgatt gaaaaaatct
    28081 gggcaatgag ttgaatcccc ataacaaggt agaccttttt gacgattgga ttatcaataa
    28141 agaagagagg ataggctagg atatagacag cagtggtcaa aatcgtacaa gcgatgcaca
    28201 aataaaaaag actagaaaag gttctgttaa gatctttttt gttatccttg acattactga
    28261 tagcccttaa accgtagtta tagacaccat aagttgcaaa gggcaagaaa aatgacaaaa
    28321 tagtgtcgac tgagttgaag taaccatagt cagttcggtc caagacacgc gcgacatagg
    28381 ttccagttag gatgggaaaa ataatattca agacacgaat tcccatgtaa gatagagcat
    28441 ttaattttat acttttcatt caatttacct cgtttttcat tatatcataa agttagctaa
    28501 taagaaatga agggcagtaa gtcaagtaat cactttgaag tttcaaatct taagttttaa
    28561 gttttcttta aggaaagtat attattctga aggactctaa aatttcgcag ccatttatta
    28621 gtaattgcta cagaattcct agtcattact agaaatggac tagtttcttt gaataataga
    28681 actgcataat tctcctattc tagaagggga ggaccagtat ttcttttatg ataggactag
    28741 attgtggtat aatagagaga ataagttttt ttagtaagac aaaggagaaa atagatgatt
    28801 tatgcaggaa ttcttgccgg tggaactggc acacgcatgg ggatcagtaa cttgccaaaa
    28861 caatttttag agctaggtga tcgacctatt ttgattcata caattgaaaa atttgtcttg
    28921 gagccaagta ttgaaaaaat tgtagttggt gttcatggag actgggtttc tcatgcagaa
    28981 gatcttgtag ataaatatct tcctctttat aaggaacgta tcatcattac aaagggtggt
    29041 gctgaccgca atacaagtat taagaaaatc attgaagcca ttgatgctta tcgtccgctt
    29101 actccagagg atatcgttgt tacccacgat tctgttcgtc catttattac acttcgcatg
    29161 attcaggaca atatccaact tgcccaaaat catgacgcag tggacacagt ggtagaagca
    29221 gttgatacta tcgttgaaag taccaatggt caatttatta cagatattcc aaatcgtgct
    29281 cacctttatc aaggacaaac acctcaaaca ttccgttgca aggacttcat ggacctttat
    29341 ggatctcttt ctgatgaaga gaaggaaatc ttgacagatg catgtaaaat ctttgtgatc
    29401 aaaggaaaag atgtggcctt ggccaaaggt gaatactcaa atctgaagat tacaaccgta
    29461 acagatttga agattgcaaa aagtatgatt gagaaagact agtaaaatga ttaatcaaat
    29521 ttatcaacta actaagccta agtttatcaa tgtcaaatat caggaagagg ctattgacca
    29581 agagaatcat atccttatcc gtcccaacta catggctgtc tgtcatgcgg atcagcgtta
    29641 ctatcaggga aaacgtgatc ccaagatttt gaataaaaag cttccaatgg caatgattca
    29701 cgagtcatgt ggaaccgtca tttctgaccc gaccggaacc tacgaggttg gtcaaaaagt
    29761 tgtcatgatt cccaatcagt ctcctatgca gagtgatgaa gaattctatg aaaactacat
    29821 gacagggacc catttcttgt ctagtggatt tgatggcttt atgagagagt ttgtttctct
    29881 ccctaaagat cgtgtggtgg cttatgatgc tattgaagat acggttgcag ccattacaga
    29941 gtttgtcagt gtgggcatgc acgctatgaa tcgtctattg actcttgctc atagcaagcg
    30001 ggagcggatc gccgttattg gagatggaag tttagctttt gtggttgcca atattatcaa
    30061 ctatactttg ccagaatcag agattgtggt tattggtcgt cattgggaaa agttggaact
    30121 cttctcattt gccaaagaat gctatattac ggataatatt cctgaagagt tggcctttga
    30181 ccatgctttt gaatgttgtg gtggtgatgg tactggacca gctattaatg acttgattcg
    30241 ctacattcgt cctcagggaa cgattctcat gatgggagtt agcgaatata aagtcaatct
    30301 caatactcgc gatgccttag aaaagggctt gattttggtt gggtcatctc gttctggtcg
    30361 cattgatttt aaaaatgcta tccaaatgat ggaagtcaag aaatttgcca atcgtcttaa
    30421 aaatatcctt tatctagaag aacctgtaag agaaattaaa gatattcatc gtgtctttgc
    30481 aaccgattta aacacagcct ttaaaacagt gtttaagtgg gaagtataag tactggaggt
    30541 taattgtgga gaaaatcatt aaagaaaaaa tttcttcctt acttagtcaa gaagaggaag
    30601 tcctcagtgt tgaacaactg ggtggaatga ccaatcaaaa ctatttggcc aaaacaacaa
    30661 ataagcaata cattgttaaa ttctttggta aagggacaga aaagcttatc aatcgacaag
    30721 atgaaaagta caatcttgaa ctactaaagg atttaggctt agatgtaaaa aattatcttt
    30781 ttgatattga agctggtatc aaagtaaatg agtatatcga atctgcgatt acgcttgatt
    30841 caacgtcaat caagaccaag ttcgacaaaa ttgctccaat attacaaact attcatacgt
    30901 ctgctaagga attaagagga gaatttgctc cttttgaaga aatcaaaaaa tacgaatcct
    30961 tgattgaaga acaaattcct tatgccaact atgaatctgt tagaaatgca gtcttctcct
    31021 tagagaaaag actggctgac ttaggtgttg acagaaaatc ttgtcatatc gatttggtgc
    31081 ctgaaaactt tatcgaatca cctcaaggac gactttattt gattgactgg gaatattcat
    31141 caatgaatga tccaatgtgg gatttggctg ccctcttttt agagtctgaa ttcacttccc
    31201 aagaggaaga aactttctta tctcactatg agagtgacca aacaccggtt tctcatgaaa
    31261 agattgctat ttataaaatt ttacaagata ctatttggag tctatggact gtctataagg
    31321 aagagcaagg tgaagatttt ggtgactatg gtgtgaatcg ttaccaaaga gctgttaaag
    31381 gtttggcttc ttatggaggt tcagatgaaa agtaaaaacg gagttccttt tggccttctc
    31441 tcaggtattt tctggggctt gggtctaacg gttagtgctt atatcttttc gatttttaca
    31501 gatttgtcac cctttgtggt ggctgcagct catgattttt tgagcatctt tatcttacta
    31561 gcttttctct tggtaaaaga agggaaagtt cgcctctcaa ttttcttaaa tattcgcaat
    31621 gtcagtgtta tcatcggagc cttgctagca ggccctatcg gtatgcaggc caatctttat
    31681 gcagttaagt atatcggaag ttctttagct tcatctgtat cggctattta ccctgcgatt
    31741 tcagttctat tggctttctt ctttttgaag cacaagattt cgaaaaatac tgtatttggg
    31801 attgtcttga ttattggagg gattattgcc cagacctata aggttgaaca ggttaattcc
    31861 ttctacattg ggattctctg tgctttggtt tgtgctattg catggggaag tgagagtgtt
    31921 cttagctcct ttgctatgga aagtgaactg agtgaaatcg aagccctctt aatccgtcaa
    31981 gtgacttcgt tcttgtccta tcttgtgatt gtgctcttct ctcatcagtc atttactgca
    32041 gtagccaatg gacaattgct aggtctcatg attgtttttg cagcctttga tatgatttcc
    32101 tacttggctt attatatcgc tatcaatcgc ttgcaaccag ccaaggctac aggcttgaac
    32161 gtgagctatg tagtatggac ggtcttgttt gcagttgttt ttttgggtgc accgctagat
    32221 atgctgacca ttatgacgtc acttgtcgtc attgctggag tttatattat tattaaagaa
    32281 taaaggagat tcgtgtgaaa gccattatct tagcagcggg attgggaact cgcttgcgtc
    32341 ctatgactga aaatacccct aaagccttgg ttcaggttaa tcaaaaacct ttgattgaat
    32401 accaaattga gtttctcaaa gaaaaaggaa tcaatgacat catcatcatt gttggttatc
    32461 ttaaagaaca attcgattac ttaaaagaaa aatacggtgt tcgcctcgtt ttcaatgata
    32521 aatacgctga ctacaataac ttttactctc tctatcttgt aaaagaagaa ttggccaaca
    32581 gctatgttat tgatgctgac aattatctct ttaaaaatat gttccgcaat gatttgacac
    32641 gttcgactta ttttagtgtt tatcgtgaag attgtaccaa cgaatggttc ttggtctatg
    32701 gagatgacta caaggttcaa gacattattg ttgatagcaa ggcaggtcgc atccttagtg
    32761 gtgtatcctt ctgggatgct ccaactgcag aaaagattgt cagctttatc gacaaggctt
    32821 atgcaagtgg tgaatttgtt gatctctatt gggacaatat ggttaaggat aatatcaaag
    32881 agctagatgt ctatgttgaa gaattagaag gcaatagcat ttatgagatc gatagtgtcc
    32941 aagactatcg taaattagaa gaaattctta aaaacgaaaa ttaaagattc caacatctga
    33001 caaaatagtc ggatgttttt tgatttttta cgaactttta cgaatagata gatgagtaga
    33061 aaaagaaatg gagttattta tgaaaatcac aaactatgaa atctataagt taaaaaaatc
    33121 aggtttgacc aatcaacaga ttttgaaagt gctagaatac ggtgaaaatg ttgatcagga
    33181 gcttttgttg ggtgatattg cagatatatc aggttgccgt aatccagccg tttttatgga
    33241 acgttatttt cagatagacg atgcgcattt gtcgaaagag tttcaaaaat ttccatcttt
    33301 ctctatttta gatgactgtt atccttggga tttgagtgaa atatatgatg cgcctgtact
    33361 tttattttac aagggaaatc ttgacctcct gaaattcccg aaggtagcgg tcgtgggcag
    33421 tcgtgcttgt agcaaacagg gagctaagtc agttgaaaaa gtcattcaag gcttggaaaa
    33481 tgaactggtt attgtcagtg gtctggccaa gggcattgac acagcagctc atatggcagc
    33541 tcttcagaat ggcggaaaaa ccattgcagt gattggaaca ggactggatg tgttttatcc
    33601 taaagccaat aaacgcttgc aagactacat cggcaatgac catctggttc taagtgaata
    33661 tggacctggc gaacaacctc tgaaatttca ttttcctgcc cgtaatcgca tcattgctgg
    33721 actttgtcgt ggtgtgattg tagcagaggc taagatgcgt tcaggtagtc tcattacgtg
    33781 tgagcgagca atggaagaag gacgcgatgt ctttgctatt cctggtagca ttttagatgg
    33841 actatcagac ggttgccatc atttgattca agaaggagca aaattgctca ccagtgggca
    33901 agatgttctt gcggaatttg aattttaaaa atgacctaag ctagaattct aagaaaaaat
    33961 caattttaag agaaaatgaa cccaacattt ccataataaa acgcatatta gcaagttttt
    34021 aacacttgct aatatgcgtt ttttctaagt ggattagtag agtagaggat ttttctcata
    34081 taatactctt cgaaaatctc ttcaaactac gtcagcttcc atctgcaacc tcaaaacagt
    34141 attttgagct gagttcgtca gtcttatcta caacctcaaa gcagtgcttt gagcaacctg
    34201 tggctagctt cctagtttgc gctttgattt tcgttgagta taagggaaag tatagtgaat
    34261 tgaaataaga tgtgaacaac tctatcagga aagtcaaatt aatttataga aatattttag
    34321 cagccaaggt gcactgttat agattcaata cactataatt tagtgtaatt gagaaaggag
    34381 aaatgattgt gattgatgtt ggctaggtta tgttcaatga ttcctaccat ctcaaatctt
    34441 gttagtaagg aaaaataaat tcttcaaaag tagagattac aaggcttgtt taagaaagaa
    34501 ttcaaagacc ttgacaaata aaaataaaat ggttattata aaaaatggtc tgaaatagat
    34561 gatgatactt ttcgaaaatc tttttacgtc agctcagctt tgccttgctg tgttttgagc
    34621 aagctacggt tagcttccga gtttgatttt catttactag aaatgaaact gatgagagat
    34681 atcagtagac atttgagtca ggatattatg gaaaatgata aaaagagctc gtgagattgg
    34741 catatcagac tactaaagta ttgagtttgt taggatttta gcgactagtt agctgggaaa
    34801 ggaagatatt tgtgacaaat aataaactgt attcgttgat agaatttaga aataaaatat
    34861 atgaagaatt agaactttcc agaagtgatt tagcgatttt actatgtgcc atgcttatcg
    34921 cctctatcgg attaaatatg gattcgactc ccgtgattat tggagccatg ttaatctctc
    34981 ctttgatgac acctattctg ggagtggggc tctctctagc tatatttgat tttaaattgt
    35041 taagaaaatc ttttaaaata ttagctattc aaattcttgc cagtttaata gcttcaacac
    35101 tttattttta tctttctccc atttcgtatg ctagttcgga aattgttgct agaacctctc
    35161 cgactatttg ggatgttctc attgcttttg taggagggat agcaggtatt attggtgcta
    35221 ggaaaaaaga gaccaataat attgttcctg gtgttgctat tgcaaccgcc ttgatgcctc
    35281 ctctttgtac agtaggttat gctattgctt ctgctaatct aaaatttatc ataggctcct
    35341 cttacctatt cctcatcaat tgtagcttta ttgtcattgc gacttatata ggtgttaggt
    35401 tgatgatggt taagaaacat tattttaaag ataatgaaga agactctaaa atgcgtagga
    35461 ttttgcttct agttgctgtt ttgctgatga ttccgagttt catctctgca acgactttag
    35521 tgagagaaac gttgaaaaaa gagtccctta agaaatttat atcagagcag tttcaggggt
    35581 ataatatttt gaaaaaaacc tattctaaaa agactcatac cctaaagcta accatttcag
    35641 gaaattattt gacagaagaa gaactcgata tgatttcaag taagagaggt gactatggtt
    35701 taagtgatgt ttctgttcaa gtttcacaat tgtctgattc agaacaactt agtaaggaag
    35761 agctggtgga gcatttcttc cagtatatca aggataagga agcaaaagaa aaggagaaag
    35821 ccaataaatt tgatacagag tctgaggagc aataatttct tgagaatagc tggtttctct
    35881 cgtgagtctt ctatgtatat caaaggaaga ctgaggtttt aagtataaaa cttttcttct
    35941 attatagtag ctaagtcttg acagggttca aaaaatggtt tacactttat aaagtttatt
    36001 actttgaaaa ggtgtgatac tgtggctacg gcaacaaaaa agaaaaaatc aacagttaaa
    36061 aaaaatctag tcatcgtgga gtcgcctgct aaggccaaga cgattgaaaa atatctaggc
    36121 agaaactaca aggttttagc cagtgtcggg catatccgtg atttgaagaa atccagtatg
    36181 tccgtcgata ttgaaaataa ttatgaaccg caatatatta atatccgagg aaaaggccct
    36241 cttatcaatg acttgaaaaa agaagctaaa aaagctaata aagtttttct cgcgagtgac
    36301 ccggaccgtg aaggagaagc gatttcttgg catttggccc atattctcaa cttggatgaa
    36361 aatgatgcca accgtgtggt cttcaatgaa atcaccaagg atgcagtcaa aaatgctttt
    36421 aaagaacctc gtaagatcga tatggacttg gtcgatgccc aacaagctcg tcggatcttg
    36481 gatcgcttgg tagggtattc gatttcgcct attttgtgga agaaggtcaa gaagggcttg
    36541 tcagcaggtc gcgttcagtc cattgccctt aaactcatca ttgaccgtga aaatgaaatc
    36601 aatgccttcc agccagaaga atactggaca gttgatgctg tctttaaaaa gggaaccaaa
    36661 caatttcatg cttccttcta tggagtagat ggtaaaaaga tgaaactgac cagcaatgac
    36721 gaagtcaagg aagtcttgtc tcgtctgact agtaaagact tttcagtaga tcaggtggat
    36781 aagaaagagc gcaagcgcaa tgctccttta ccctatacca cttcatctat gcagatggat
    36841 gctgccaata aaatcaattt ccgtactcga aaaaccatga tggttgccca acagctctat
    36901 gaaggaatta atatcggttc tggtgttcaa ggtttgatta cctatatgcg taccgattcg
    36961 actcgtatca gtcctgtagc gcaaaatgag gcggcaagct tcattacgga tcgttttggt
    37021 agtaagtatt ctaagcacgg tagcaaggtc aaaaacgcat caggtgctca ggatgcccat
    37081 gaggctattc gtccgtcaag tgtctttaat acaccagaaa gcatcgctaa gtatctggac
    37141 aaggatcagc tcaagctata tacccttatc tggaatcgtt ttgtggctag ccagatgaca
    37201 gcggccgttt ttgataccat ggctgttaaa ttgtctcaaa aaggggttca atttgctgcc
    37261 aatggtagtc aggttaagtt tgatggttat cttgccattt ataatgattc tgacaagaat
    37321 aagatgttac cggacatggt tgttggagat gtggtcaaac aggtcaatag caaaccagag
    37381 caacatttca cccaaccgcc tgcccgttat tctgaagcaa cactgattaa aaccttagag
    37441 gaaaatgggg ttggacgtcc atcaacctac gcgccaacca ttgaaaccat tcagaaacgt
    37501 tattatgttc gcctggcagc caaacgtttt gaaccgacag agttgggaga aattgtcaat
    37561 aagctcatcg ttgaatattt cccagatatc gtaaacgtga ccttcacagc tgaaatggaa
    37621 ggtaaactgg atgatgtcga agttggaaaa gagcagtggc gacgggtcat tgatgccttt
    37681 tacaaaccat tctctaaaga agttgccaag gctgaagaag aaatggaaaa aatccagatt
    37741 aaggatgaac cagctggatt tgactgtgaa gtgtgtggca gtccaatggt cattaaactt
    37801 ggtcgttttg gtaaattcta cgcttgtagc aatttcccag attgccgtca tacccaagca
    37861 atcgtgaaag agattggtgt tgagtgtcca agctgtcatc agggacaaat tattgagcga
    37921 aaaaccaagc gtaatcgcct attctatggt tgcaatcgct atccagaatg tgaatttacc
    37981 tcttgggaca agcctgttgg tcgtgactgt ccaaaatgtg gcaacttcct catggagaaa
    38041 aaagtccgtg gtggtggcaa gcaggttgtt tgtagcaaag gcgactacga ggaagaaaag
    38101 attaaataag aggaggggcc cgaaagtaaa tttcaggctc cttttggtta gaacttgaca
    38161 aaatacatca ttttatgcga aactagaaga agattatttt atactcaatg agaatcaaag
    38221 agcaaattag aaagctagtc gcaggttgct caaagcacta ctttgaggtt gaagatggaa
    38281 gctgacctgg tttgaagaga ttttcgaaga gtattaacta ggagaagtta tgcgtcttat
    38341 ctatctaatt attggttttt tatcgctggc cttggctatt gttggggttg ttttaccctt
    38401 gttgccgaca acgcctttcc ttttgttgtc tattgcttgt ttctccagaa gttccaagcg
    38461 tttcgaagac tggctttatc ataccaagct ctatcaaaca tatgtagctg attttcgcga
    38521 gactaagtct attacgcgtg aacgaaagaa aaaaatcatc gtctctatct acgtcttgat
    38581 gggaatttct atttattttg cacctctttt accagtcaaa atcggtctgg gtgctttgac
    38641 catctttatc acttattatc tcttcaaggt cattccagac aaagaatagt taaaacagta
    38701 gttatttgcc ttgataaaat tgaaagcata ttcataacaa tatgatataa taaatttgaa
    38761 gtaatattca aggagaatca aatgatttac gaattttgtg ctgaaaatgt gactttactt
    38821 gaaaaagcga tgcaggctgg agctcgtcgg attgaactct gtgataatct agcagttggt
    38881 gggacaacac ccagctatgg agtgactaag gcagcggttg aactggcagc taactacgat
    38941 acaaccatca tgaccatgat tcggccacgt ggtggtgact ttgtctataa tgacctagaa
    39001 attgctatca tgctagaaga catttgtttg actgctcagg ctggaagtca aggggttgta
    39061 tttggagctt taactgctga taaaaagttg gataagccta atctggaaaa gttaattgct
    39121 gcatcaaaag gaatggaaat tgtctttcac atggcctttg atgaactaag tgatgaagat
    39181 caaccggaag ctattgactg gctcagtcaa gccggtgtca ctcgtatcct aactcgtgct
    39241 ggtgtgtctg gcgactcctt agaaaaacgt tttgttcact atcacagaat tttggagtac
    39301 gctaaaggta aaattgaaat tctaccaggt ggggggattg accttgacaa ccgtcaaacc
    39361 tttattgacc aggtgggggt aacacaattg catggcacta aggttgtttt ttaaaaaata
    39421 gaaaggaact gctagccttg ggtagcagtt ttcacttatg tttgaaattt ttaaatccta
    39481 tcaatttaat caagaaaagg ctcatgatta tggttttata gaaaatagcg aagtctggac
    39541 atatagttgc cagattttgc aaggtgactt tgtcatgact gtgtccatca ctgctgataa
    39601 tttgaacttt caagtctttg accaagagac tggtgacctc tatcctcacg ttcatatgga
    39661 aagcatgagg ggaagttttg tcggaaatgt ccgtgaggct tgtctggaga ttctttacca
    39721 gattcggaag gcttgttttg atgtgcaaga ttttatctgt catcagacta agcgtatcat
    39781 gactcaagtt caggaaaagt atggaaacca gttggagtat ctgtgggaaa aatcgcctga
    39841 tacagctgta ttgcgccatg aaggcaatca aaagtggtat gccgtcttga tgaaaatctc
    39901 ttggaataag ctggaaaagg gcagagaagg acaagtggaa gcagtcaacc tcaagcatga
    39961 ccaagtagct aatttgcttt cacaaaaggg gatttatcca gccttccata tgagcaagcg
    40021 ctactggatt agtgtgtccc ttgatgatac tttatcagat gaagaagtac tggaattgat
    40081 agaaaaaagt tggaacttaa cctctaaaaa atgaaatatt ttaataattt tcatgaactt
    40141 tcaattagct aaatattctt tactgaagaa attttcagaa aatataggat ttaccacacc
    40201 agaggaatgt ggtgccatct tcaaatacct gattgagaat gtcaagacgg atcgtcagat
    40261 catctattcg cctcactgtc atgatgacct cggaatggca gtggcaaata gccttgctgc
    40321 tgtcaagaat ggtgcaggac gtgttgaagg gactatcaat ggtattaggg agcgagctga
    40381 aaatgctgct ttggaagaaa ttgcagtggc tctcaatatt cgccaagatt actaccaagt
    40441 agaaaccagt attgtcctaa atgagaccat caatacgtca gaaatggttt ctcgcttctc
    40501 tggtattcca gttcctaaaa acaaagccgt cgttggtggc aataccttct cccacgaatc
    40561 tggtattcac caagatggag tccttaaaaa tcctctcact tatgagatca tcacacctga
    40621 attggttggt gttaagattc cgcttggaaa attatctggt cgccatgctt ttgttgagaa
    40681 actgagagaa ttggccctag attttacaga agaggatatc aaaccactct ttgctaagtt
    40741 caaggcactg gccgataaga agtaagaaat cacagatgca gatactcgag ctttggtagc
    40801 tggaaccatg gttgaaaatc cagaaggctt ccactttgat gatttacaac ttcaaactca
    40861 tgcagataat gacattgaag cgctcgttag cctagccaat atggatggtg agaaagtcga
    40921 atttaatgcg acagggcaag gttccgttga agcaatcttt aacgctatcg ataagttctt
    40981 taactaatct gttcgtttgg tgtcctacac tatcaatgcg gtaacagatg gaatcgatgc
    41041 ccaggatcgg gttttggtca ctgttgaaaa cagagataca gaaaccatct ttaatgcagc
    41101 agggcttgat tttgatgtgt tgaaggcttc tgctattgcc tatataaacg ctaatacctt
    41161 tgttcaaaaa gagaatgcag gtgagatggg acgcagtgtt tcttaccacg atatgcctag
    41221 tgtgtaaagg agaaggctat ggcaaagaaa atagtagctc tagtaggaga cggaattggc
    41281 ccagaaatca tggaggctgg tttagaagtt ctggaggctc tagctgaaaa aacaggtttt
    41341 gactatgaga ttgacagacg accgttcgga ggtgcagata ttgatgcagc aggacctccc
    41401 ttacctgatg aaacccttaa ggcaagtagg gaagcagatg ctatcctact agcagctatc
    41461 ggtagtcctc agtatgatgg agcagcggtt cgccctgaac aaggcctgat ggctctccgt
    41521 aaggaactca atctttacgc taatattcgt cctgtaaaaa tctttgacag tctcaagtat
    41581 ttgtcaccac tcaaaccgga acgaatttct ggtgtagact ttgtcgtggt gcgtgaattg
    41641 acaggcgaga tttactttgg agatcatatt cttgaagagc gcaaagcgcg tgatatcaac
    41701 gactatagct atgaggaagt ggagtggatt attcgcaaag cctttgaaat tgcaagaaat
    41761 cgcagaaaaa tccttactag tatcgataag caaaatgttc tagcgacctc aaaactctgg
    41821 cggaaagtag ctgaggaagt cgcacaggat ttctcagatg taaccttgga acaccagctg
    41881 gtagactcag ctgctatgct tatgattacc aatcctgcta agtttgatgt tattgtaacg
    41941 gagaatcttt ttggagatat tttatctgat gaatcaagcg ttttatctgg tacacttggg
    42001 gttatgccat cagccagtca ttctgaaaat ggaccaagtc tctatgaacc tatttacggt
    42061 tcagcacctg atattgcagg tcaaggaatt gccaatccta tttccatgat tttatcagtt
    42121 gccatgatgt tgagagatag tttcggaggt tatgaggatg cagagcgtat caaacgtgct
    42181 gttgagacaa gtctggcggc aggaatttta acgagagata taggaggtca ggcttcaaca
    42241 aaggaaatga cggaagctat tattgcaagg ttatgaagtt agacgaaaaa attactctag
    42301 tccttttgat ttggaatgtc atcattttct tgatttatgg cattgacaaa ttcaaggcaa
    42361 gaagaagagc ttggcgcatc caagagaaaa tcttactcat tttagccctt acttgtggtg
    42421 gttttggggc ctggttagct ggaatcactt ttcaccacaa gactcgaaaa tggtacttta
    42481 aaacagtttg gtttcttggg atggtgacca cactagtagc cttatatttt atttggaggt
    42541 aatggatggc agggtcttcg agggaatacg ctgcttgggc tctagcggac tatggtttta
    42601 aggtcgtgat tgcaggatct ttcggtgaca ttcattacaa taatgaactc aataatggca
    42661 tgttgccaat cgttcagcct agagaggtta gagaaaagct agcccaactc aaaccgaccg
    42721 accaggtaac tgtagacttg gaacaacaga aaattatctc accagttgaa gaattcacct
    42781 tcgagataga tagcgagtgg aaacataaac tcctaaatag tttggatgat atcggtatta
    42841 ccttgcagta tgaagagttg attgctgctt atgaaaaaca acgaccagcc tactggcagg
    42901 attagaaaaa atagaaaagg aaatatagta aactgaaata agatgtaaac aaatgaattg
    42961 gagcttaaca tccatttcca gcaatttttt agaaactaca gtggactatt ctggattcaa
    43021 cacattataa aattatgaca aaacacattc acaagaaggc tacgacattt taaaaggtga
    43081 gggcggatgt atcgtttgcc ctactaaagt tggttacatt atcatgacca gcgataaggc
    43141 aggacttgag cgtaagtttg cagccaaaga acgtaagcgt aacaaaccag gtgttgttct
    43201 ctgcggtagc atggatgaac tttgcgcttt agcgcaactc aacccagaaa ttgaagcatt
    43261 ctactaaaaa cattgggatg aagatattct tcttggttgt atccttcctt ggaaaccaga
    43321 agcctttgaa aaattcaaag catacgggga tggccgtgaa gaacttatga ctgatgtacg
    43381 tggtactagc tgttttgtta tcaagtttgg aaaagcagat gaacaattgg ctgccaagct
    43441 ttgggaagaa ggtaaaatgg tctacgcctc atctacttca atgataaaac gattgaaact
    43501 cgctatgaga gcaaggtgta atggtgtcta tggtcgataa gaacggcaaa ctcatcccag
    43561 aacaaggagg agcacgttca acttcaccag ctccagttgt gatccgtaaa gggcttgaca
    43621 ttgataaaat catgatgcac ctgtcagata cttttaactc atgggactac cgtcaggttg
    43681 agtattatta ggatagagaa gaagtctagt gttaaggaca ttacagctca taatactagg
    43741 cttttttata gaaattcttt tctttttcta taggatatgg tattctatgt agaaaatata
    43801 tgttaataag taatgccaat atttaaacat cattagtaaa aggagttaga ttgatgaata
    43861 aaagaaaagt tagtttagaa gatttttata aatggtatag tctaaataaa gaaaagttat
    43921 taaataaggc aactgttggt gaaaagttta atgataaatt aaaagaagag tttctccagg
    43981 aatggccttt ggataggatt ttaacaatgt caatcgatga atatgtaata ggaaagggac
    44041 agcaaaataa gtctttatgc tacgctcttg agaagggaaa atacaaaaat ctatttcttg
    44101 gaatttctgg tggctcagct tcaaaatttg gtatttattg gaataaaaaa acaaacaaat
    44161 ataaagatca agctaataat gagatttcag agttggatca gcgattttca aaattaaaat
    44221 cagatttgta tgaaattatc aaagaaggta ttcgttttaa ctttgaaaat cctatttttg
    44281 atatgaaaag atcaacaaat gaatttattg gtcgttctgc tatggtgaca aaattacttt
    44341 gtatctattc tgggggagat cctttctttg gtgtaaatat taatagtcag aaagaatttt
    44401 ggaaccactt tgtttctcag acaaatcaag gtggacctta tctgcaaaat cataaaataa
    44461 ttgaactggt gtccaaaact tatcctgagt tggagccatc gaaattagga actatgcttt
    44521 ttgagtattc taagcttttt atggaaaata aggaagacaa tagtacaatg gattcatcaa
    44581 acaattttcg tcatcaatta actcaatctc tattaaagtc tccaaacctt atccttcgtg
    44641 gtgctcctgg cacaggaaag acttatcttg ctaaagaaat tgccaaagaa ttaacggatg
    44701 gcaacgaaga ccaaatcgga tttgtacaat ttcacccatc ctatgattat acggattttg
    44761 tagaaggttt aagaccagta tcaaatgggg atggagctat tgagtttagg ctacaggacg
    44821 gtatttttaa agatttttgt cagaaagcaa aagaaaccca attgattgga ggacaagata
    44881 attttgatga ggcttgggat tcttacttag aatatataaa tgttgctgaa gaaaaagaat
    44941 atataacaaa aacatcttac ttatctgtta atagtagaca aaatttgtca gtaaattatg
    45001 atagtggtgt tccaggatgg tcactaccta gcaaatatgt ttacgagttg tataaagata
    45061 aaaattataa taagcaagaa tactacaaaa gtggtggaaa aactgtccta gaaacattga
    45121 gaaagagatt tggtttgaaa gactatgttt ccccaacaga aattgatact gataagaaat
    45181 tcgtcttcat catcgatgaa atcaatcgtg gggagatttc taagattttt ggcgaactct
    45241 ttttctctat cgaccctggc tatcgtggtg aaaaaggaag tgtttctacc caatatgcaa
    45301 atctacacga aactgatgaa aagttctata tccccgaaaa tgtttacatc atcggaacta
    45361 tgaatgatat tgatcgttca gtggatacct ttgattttgc tatgcgtcgt cgttttcgtt
    45421 ttgttgaagt tactgccgag ggtcaagttg gcatgttgga taaagagctg aatatccatg
    45481 cagaagaagc aaaaattcgt ctaagaaact tgaacgctgc tatcgaaaat gttcaggaat
    45541 taaacagtca ttatcatatt ggaccaagtt attttcttaa gttgaaggat gtagattttg
    45601 actatgaatt actctggtct gattatatta agcctctcct agaagactac ttgcgaggtt
    45661 cttatgatga ggttgaaact ttggaaactt tgaaaaaagc atttgaactg acaaataatg
    45721 agcaaaaaga tcaggcagta gctgatgaca atgaaggtga tgaaaacgat gatgcggatt
    45781 actgataatc aacacaagat tattaaagaa aaatttgttg aagaatatcc taaactaagc
    45841 aatcttcttt tagacagaac cttggaaagt ctatcccaag atgaacgtat tttcattttt
    45901 ccaaatgatt tgactcatac tcctgatttg gataaggacc aaaagatttt tgaaacagtc
    45961 aatcagaaaa tcaagacagg gaacgtgatt ggttttcttg gatatggtca ggaaagatta
    46021 acgatttcct cacgattttc tgatgagagt aatgaccatt ttttgcatta tctcttaaac
    46081 aaggttcttc atatcaatct cactagttta gatgttgctt tgtctcgtga agagaggctt
    46141 tatcaacttt tggtgtatct ctttcccaag tatctacaag ctgctattcg aaaaggtctt
    46201 tataaggaat atcatcgatt ttctcataac gacagtaatg ttaagggagt gattgatgta
    46261 agaagccatc tcaagaaaaa tcttcctttc acgggaaata ttgcctacgc aacgagagag
    46321 ttcacctatg ataatcccct catgcagttg gtccgtcaca ctattgaata cattaagaat
    46381 cagaaaagca ttggtcaagg ggtactagat aatctctcaa ctagtcgtga aaacgtatct
    46441 gaaatcgtgc gtgtaacgcc ctcttataaa ctagctgatc gtgctaagat tattcgggga
    46501 aatcaatcta aacctatacg tcatgcatac tttcacgagt acagaaactt acaagaactt
    46561 tgtctgatga tcctaaacca agaaaagcac ggtttagggt atcaagatca aaaaatctat
    46621 ggtattctct ttgatgttgc ctggctttgg gaagagtatg tttacacctt gttgccaaaa
    46681 ggttttgtac atcccagaaa taaggataag acggatggaa tttcagtatt ttctgttggg
    46741 aaacgaaaag tatatccaga tttttatgac agagaacgaa agattgttct agatgcaaaa
    46801 tataaaaaac tggaattgac tgaaaaagga atcaaccgtg aggacttatt ccagctgatt
    46861 tcctattctt atattttaaa agctgagaag gctggactga tttttcctag tatggagcag
    46921 tcagtaaata gtgaaatagg aaaagtagct ggctatggag ctcaattgaa gaagtggtct
    46981 attcgaatcc ctcagaatgc ctcattctat agtacatttt gtaaaatgat ggaaaattca
    47041 gaagaaaatt ttaaagcgat tattgatgaa gaagtgggga gaaaataatt tcccctcttt
    47101 cttttatttt taacacaagt aaaacccgaa cgatatattt taattcataa aataatttga
    47161 caaaaactgt actttggttt ataataaatt aaggaaacgt cggaaaaggc gtagtgatgc
    47221 aagagcatag gtaggtcatt acaaaagaaa cgagacatcg atatgttaaa tgaatttcca
    47281 atttttgatt acgaagatat tcaattgatt ccaaataaat gtgtcattaa aagccgtgca
    47341 gaagcggata caagtgtcac tttaggaaat cacaccttta aactacctgt tgtgccagcg
    47401 aatatgcaga cgattttgga tgaaaatgta gcagagcaac tggctaaagg tggttacttc
    47461 tacattatgc accgttttga tgaggcagga cgcattcctt ttattaaacg aatgcacgat
    47521 caagggctca ttgcttctat ctctgtcggt gttaaggatt atgagtatga tttcgttaga
    47581 cagctcaaag ctgatgctcc tgagtatatc actattgata ttgctcatgg tcatgcggat
    47641 agcgtgattt ctatgattca acacatcaag aaagaattgc cagatacctt tgtcattgct
    47701 ggaaatgtgg gaacaccaga agctgtgcgt gaattggaaa atgctggtgc ggatgctact
    47761 aaggtcggaa tcggtcctgg taaggtttgt atcaccaagg ttaagactgg ttttggtaca
    47821 ggtggttggc agttggctgc tctacgctgg tgtgccaagg ctgcgcgtaa accgattatc
    47881 gctgatggag gaattcgtac tcacggtgat attgctaagt ctatccgctt cggtgctagc
    47941 atgatcatga ttggttccct ctttgcagga cacattgaaa gtccagggaa aacgattgaa
    48001 gtcgatggtg aacagttcaa agaatattat ggttcagcct cacaatatca aaaaggtgct
    48061 tacaaaaatg tggaaggcaa acgtatcttg cttcctgcta aaggtcatct gcaagacact
    48121 ttaactgaga tggaacaaga ccttcaaagt gctatttctt atgcaggtgg acgtcaggtt
    48181 gctgacctta aacacgttga ttatgtgatc gtgaaaaact ccatctggaa tggggatgct
    48241 tcccactaag acggggtctt tgaccaaaaa acttgttatt agagcaaatt tctgttataa
    48301 taaaacaagt ttccaccctt agtgtaatgg atatcacgta agattccggt tcttgagatg
    48361 ggggttcgat tccctcaggg tggatgtaaa catcctaaaa agcctttaat agggcttttt
    48421 tctttatcct gacccaaatt tgccgctaaa actgagaatc tctgtctaaa gaattcccaa
    48481 atgctttcca gtcccgtttt agagtgactc agggggcttt ttttgatata ataaaaagga
    48541 ctattatcag ttagaaagag gttggtatga aagaattaca aactgtacta aagaatcatt
    48601 ttgcaatcga atttgcagac aaaaatttac tggaaactgc ctttactcat acgagttatg
    48661 ccaatgagca ccgcctctta aaaatttcac acaatgaacg cttggaattt ttaggagacg
    48721 ctgttctaca gttattgatt tcagaatatc tatataaaaa atatcctaaa aagcctgaag
    48781 gtgacctatc aaaactccgt gctatgattg tccgtgagga gagtttagct ggttttgcgc
    48841 gtgattgcca gtttaaccag tttatcaagt tgggtaaagg ggaagaaaaa tcaggtggtc
    48901 gcaatcgtga caccattctt ggtgatgcct ttgaagcctt tcttggtgcc cttcttttgg
    48961 ataaggatgt ggccaaggtc aaggaattta tctatcaagt catcattcct aaggttgaag
    49021 caggcgagtt tgagatgatt acagactata aaacccatct ccaagagttg cttcaggtca
    49081 atggtgatgt ggctattcgt tatcaggtga tttctgaaac agggcctgct catgataagg
    49141 tctttgatgt agaagttctt gttgaaggta agagcatcgg tcaaggccaa ggtcgttcta
    49201 agaaattagc agagcaggaa gctgccaaaa atgccgttga gaaggggctg gattcatgta
    49261 tttaaaggaa atcgaaattc aggggttcaa gtcttttgct gataagacca aggtcgtttt
    49321 tgaccaaggt gtgacggcag ttgttggacc caatggatct ggaaagtcca atattacaga
    49381 aagtctgcgt tgggctttgg gggagtctag tgtcaagagt ctccgtgggg gcaagatgcc
    49441 ggatgtcatc tttgctggaa ccgaaagtcg caaaccgctc aattatgctt ctgtagttgt
    49501 gactctggat aatcatgacg gatttatcaa ggatgcaggt caagaaatca gggtggaacg
    49561 ccatatctat cgtagtggag atagcgaata caagattgac ggcaagaaag tccgtctgcg
    49621 tgatattcat gacctcttct tggatactgg attgggacga gattccttct ctattatttc
    49681 ccaagggaag gttgaggaga tttttaattc caagcctgag gaacgacgag ctatttttga
    49741 agaagctgct ggagttttaa aatacaagac tcgcagaaaa gaaaccgaga gtaaactgca
    49801 gcaaactcag gataatctgg accgcttaga ggacattatc tacgagttgg ataatcaaat
    49861 caagcctctt gagaagcaag ctgagaatgc ccgtaagttt ttagacttgg aaggacaacg
    49921 taaggctatt tatttagacg ttctggttgc tcaaatcaag gaaaataagg ctgaactaga
    49981 gtcgacagaa gaagagttga ctcaggttca agaactcttg atgagttatt accaaaagcg
    50041 tgaaaaatta gaagaagaaa atcaaactct taaaaagcaa cgccaagatt tacaggctga
    50101 aatggccaaa gaccaaggca gtttgatgga cttgactagt ctgattagtg atttagaaag
    50161 aaaattagcc ctatcgaaac tggagtccga gcaagtggcc ttgaatcaac aggaggcaca
    50221 agcccgtttg gctgctttgg aggataagag aaattcactc agcaaagaaa agtctgataa
    50281 agaaagctct ttagctctgt tagagggaaa tctagtccaa aataatcaaa aactcaatcg
    50341 tttagaagct gaattgctgg ctttttcaga tgatcctgat cagatgattg agcttttgcg
    50401 tgaacgcttt gtggcgcttt tacaagaaga agcggatgtc tcaaaccaac tgacccgcat
    50461 cgagaatgag ttggaaaata gtcgtcagct ttctcaaaaa caagcagatc aactagaaaa
    50521 gctgaaagag caattggcta tagctaaaga gaaggctagt cagcaaaagg aagagcttga
    50581 aactgccaag gagcaggttc agaaattatt ggctgactat caagctattg ccaaggagca
    50641 agaggagcaa aaaacttcct atcaagctca acaaagtcaa ctctttgacc gtctggatag
    50701 tcttaaaaac aagcaggcta gagctcaaag tttggaaaac atccttagaa atcacagtaa
    50761 cttttatgca ggtgtaaaga gtgttctcca agaaaaagac cgccttggtg ggattattgg
    50821 tgctgttagt gagcatttga cctttgatgt gcattatcaa actgccttag agattgcact
    50881 tggagccagc agtcagcata tcatcgtaga agatgaagag tcggcaacca aagctattga
    50941 tttccttaaa cgaaacagag ccggtcgtgc aaccttcctt ccgttgacaa caatcaaggc
    51001 tcgtacgatt tctagccaga atcaagatgt tatcgctgta agcccaggtt tccttgggat
    51061 ggcagatgag ttggtgactt ttgatactag actggaagcc attttcaaga atttgctagc
    51121 tacgacggct atttttgata ctgtagagca tgcgcgtgca gcagctcgcc aagttcgtta
    51181 tcaggttcgt atggtgacat tggatgggac agaattacgc acgggtggtt cctatgcggg
    51241 tggtgccaat cgccaaaata acagtatttt catcaagcca gaactggagc aattacaaaa
    51301 agaaattgct gcagatgaag caagcttggg ttcagaagaa gcggctttga agaccttgca
    51361 agaccagatg gctacattga cagaaagatt agaagccatc aaatctcaag gagaacaggc
    51421 acgtattcag gagcaaggct tgtccctcgc ttatcagcaa actagtcagc aagttgaaga
    51481 actggaaact ctttggaaac tccaagaaga ggaaaaagat cgtctttctg atggagattg
    51541 gcaagcagac aaggaaaact gccaagagcg tcttgctgca atcgccagtg acaagcaaaa
    51601 tctggaagct gagattgaag agattaagtc taataaaaat gccatccaag aacgctatca
    51661 aaacttgcag gaagagctag cgcaagctcg tttgcttaag acagaactgc aagggcaaaa
    51721 acgttatgaa gtggctgata ttgaacgctt aggcaaggaa ttggacaatc ttgattttga
    51781 acaagaggaa atccagcgcc ttcttcaaga aaaggttgac aatcttgaga aggttgatac
    51841 agaattgctc agtcaacagg cggaagaatc caaaactcag aaaacgaact tccaacaagg
    51901 tttgattcgc aaacagtttg agttggatga tatagaaggt cagctggatg atattgctag
    51961 tcatttggat caggctcgcc agcagaatga ggagtggatt cgcaagcaaa cacgtgctga
    52021 agccaagaaa gaaaaggtca gcgagcgctt gcgccatcta caaagtcaat taacagacca
    52081 gtaccagatt agctatactg aagctctaga aaaagcgcat gaattggaaa acctcaatct
    52141 ggcagagcaa gaagttaagg atttagagaa ggctattcgc tcactgggtc ctgtcaatat
    52201 agaagctatt gaccagtacg aagaagttcg caaccgtctg gactttctaa atagtcagcg
    52261 agatgatatt ttgtcagcga aaaatctgct ccttgaaacc attacagaga tgaatgatga
    52321 ggtcaaggaa cgctttaaat caacctttga agctattcgt gagtccttta aagtgacctt
    52381 caagcagatg tttggcggag gtcaggcaga cttgatattg actgagggcg accttttaac
    52441 agctggtgtg gagatttctg ttcaacctcc aggtaagaaa atccagtcgc ttaacctcat
    52501 gagtggtggt gaaaaagctc tatcggctct tgccttgctt ttctccatta ttcgtgtcaa
    52561 gactattcca tttgttatct tggatgaggt ggaagctgcg ctggatgaag ctaatgttaa
    52621 acgttttggg gattacctca accgctttga caaggacagc cagttcatcg tcgtaaccca
    52681 ccgtaaggga accatggcag cggctgattc tatctatgga gtgaccatgc aagaatcagg
    52741 tgtctcaaaa attgtttcag ttaagttaaa agatttagaa agtattgaag gatgacaatt
    52801 aaactagtag caacagatat ggatggaacc ttcctagatg agaatgggcg ctttgatatg
    52861 gatcgcctca agtctctctt ggcttcctat aaggaaaaag ggatttactt tgcggtggct
    52921 tcgggtcggg gatttctgtc tctggaaaaa ttatttgctg atgttcgtga tgacattatt
    52981 ttcatcgcgg aaaatggcag tttggtagag tatcaaggtc aggacttgta tgaagcgact
    53041 atgtctcgtg acttttatct ggcaactttt gaaaagctga aaacgtcacc ttatgtagat
    53101 atcaataaac tgctcttgac gggtaagaag gggtcatatg ttctagatac ggttgatgag
    53161 acctatttga aagtgagtca gcattataat gaaaatatcc aaaaagtagc gagtttggaa
    53221 gatatcacag atgacatttt caaatttaca accaacttca cagaagaaac gttagaagct
    53281 ggtgaagctt gggtcaatga taatgtccct ggtgtcaagg ctatgacaac tggctttgaa
    53341 tctattgata ttgttctgga ctatgtcgat aagggtgtag ctattgttga attagctaaa
    53401 aaacttggta tcacaatgga tcaggtcatg gcttttggag acaatcttaa tgacttacat
    53461 atgatgcagg ttgtgggaca tcctgtagct cctgaaaatg cacgacctga aattttagaa
    53521 ttagcaaaga ctgtgattgg tcaccataag gaacggtcgg ttatagctta tatggagggc
    53581 ttataatggc agatataaaa ttgattgcat tggacttgga cgggaccttg ctgactactg
    53641 ataaaaggct gacggatcgt accaagtcaa ccttgaaagc tgcgcgtgat cgtggtatca
    53701 aggtcgtatt gacaactggt cgtcccttaa aagccatgga cttctttctc catgagttag
    53761 ggactgacgg ccatgaagat gagtatacca ttacttttaa tggtggtttg gttcagaaaa
    53821 atacaggtga aatccttgat aaaacagtct tttcatatgc tgatgtggca cgcttgtatg
    53881 aggaaacaga gaaattatca ctgcctcttg atgccatctc agaaggaaca gtttatcaaa
    53941 tccaatcgga ccaagaaagt ctttatgcca aattcaatcc agctttgact tttgttccag
    54001 ttgactttga agacctgtct agtcaaatga cctacaacaa atgcgtgact gcctttgctc
    54061 aagaaccctt ggatgcagcc attcagaaga tttctccaga attgtttgac caatatgaaa
    54121 tctttaaatc acgtgaaatg ttgctagaat ggtcaccaaa gaatgttcat aaagcaacag
    54181 gtttggcaaa actaatcagc catcttggaa tcgaccaaag ccaagtgatg gcttgtggtg
    54241 acgaggccaa tgacctctct atgattgaat gggcaggtct tggtgttgct atgcaaaacg
    54301 ctgttcctga agtaaaggca gccgcaaatg tagtgacgcc gatgaccaac gatgaggaag
    54361 ctgtcgcctg ggctatcgaa gaatatgtgt taaaggagaa ctaagatatg ggattatttg
    54421 accgtctatt cggaaaaaaa gaagaaccta aaatcgaaga agttgtaaaa gaagctctgg
    54481 aaaatcttga tttgtctgaa gatgttgatc ctaccttcac agaagttgag gaagtttctc
    54541 aggaagaagc agagatggaa attgttgaac aagctgtgtt ccaagaagag gaaatccaag
    54601 acacagttga agaaagtctg gatttagagc cagttgtaga agtttctcaa aaagaagtag
    54661 aagaatttcc aaactcacaa gaagtcacag aggaagagaa gcttgagcac gaaggaactg
    54721 tagaagaaaa taattctgaa gtgcttgaac cagaagctcc tcaaacagaa gaaactgttc
    54781 aggaaaaata tgaccgcagt cttaagaaaa ctcgcacagg tttcggtgcc cgcttgaatg
    54841 ccttctttgc taacttccgc tctgttgacg aagaattttt cgaggaactg gaagaactgc
    54901 tgattatgag tgatgttggt gtccaagtcg cttctaactt aacggaggaa ctacgttacg
    54961 aagccaagct tgaaaatgcc aagaaacctg atgtacttcg tcgtgtcatc attgagaaat
    55021 tggttgagct ttatgaaaag gatggtagct acgatgaaag catccacttc caagataact
    55081 tgacagttat gctctttgtt ggtgtgaatg gtgttgggaa aacaacttct atcggaaaac
    55141 tagcccaccg ctacaaacga gctggtaaga aggtcatgct ggttgcagca gataccttcc
    55201 gtgcgggtgc agtagctcag ctagctgaat ggggccgacg agtagatgtt ccagtagtaa
    55261 ctggacctga aaaagctgat ccagccagcg tggtctttga tggtatggaa cgtgccgtgg
    55321 ctgaaggtat cgatattctc atgattgata ctgctggtcg tctgcaaaat aaggataacc
    55381 ttatggctga gttggaaaag attggtcgta ttatcaaacg tgttgtgcca gaagcaccac
    55441 atgaaacctt cttggcactt gatgcatcaa caggtcaaaa tgccctagta caggccaaag
    55501 aattttcgaa aatcacacct ttaaccggaa ttgttttgac taagattgat ggaactgctc
    55561 gaggaggtgt ggttctagcc attcgtgaag aactcaatat tcctgtaaaa ttgattggtt
    55621 ttggtgaaaa aatcgatgat attggagagt ttaactcaga aaactttatg aaaggtctct
    55681 tggaaggttt aatctaatca gaagcaaaaa tcctgcaagg cataaacttg caggaaattt
    55741 ttttattcta agcgaccatc ttgacgatag gcgatatctg gttgccaagt ccatttggca
    55801 ccgaattttt caagtaggtc aaagctggct tgaggtccca tgcttccagc tttatagtca
    55861 tgaagtgggg caccattttc agcccagagc ttttcaatac gatcaatcaa cttccatgac
    55921 gcaccaactt catcccagtg gctaaagtta gttgagttgt tatttaggac atcataaatc
    55981 aatttttcgt atggttctgg agaagcacca gttgcagtcg cgtctgtacg ataatcaagt
    56041 gagttaggag ccaagttaaa ttcttctcct acttgcttcc catttaggct aagagagaag
    56101 ccttctgttg gttgaatata gatggtcaaa atatttggag caagtggttc tccaaagata
    56161 gaatccattt gtttaaagac gatgttgaca tgagttcctt tttcagtcag tcgtttacct
    56221 gtacggaaaa agaaaggaac accacggaat cgatcgctgt ctacaaagaa ggcaccagat
    56281 gtaaaggttt cagttgttga ttctggattc acatttggct cgctacgata agagatgtat
    56341 tttatgccat caatcttacc agagcggtat tgcccacgga taaagtgttc tttgagttct
    56401 tcatcagttg gatgatagag gtttttaaag accttaatct tttcagcacg aatctcgtct
    56461 tttgtgaagc ttgctggttt gtccatggcg agaagcgaaa gaagttgtag agtgtggttt
    56521 tggaccatgt cacggagggc accggattgg tcatagtagc caccacgttc ttctacaccc
    56581 aagcgctccg caaaggtaat ttgaacattg tcgataaaat ccttgttcca aacgttttca
    56641 aaaatcaagt ttgcaaagcg aactgcaaag atgctttgga tcatttcctt accaagataa
    56701 tggtcgatac ggaaaatttg ttcttcgtca aatgttgcta ggagttcgtc attcaacttg
    56761 cttgcagttg cgtaatctgt accaaatggt ttttcaacga tcaagcgctc aaaacctttg
    56821 ccatcgacaa tgttttcaga tttgaggtgt ttggcaatgg ttccaaagaa ctgaggtgcc
    56881 atagacaaga agaagagctt attgtgttca gcttggtatt tttcattaag ctcagcttgt
    56941 aattgacgca aagcaatata atgttccgaa tcattgacat catggctttg atagtagaag
    57001 tggctagcaa attcttgggc ttgctcggta ctatctgcca aatcaaggat ggactcgaca
    57061 actacagatt caaaatattc cttactccaa ggtctacggg cagttccaat aacggcaaag
    57121 tgcttggaaa gattgccgga tttatatagt ctaaaaaggg aagggtagag cttgcgttta
    57181 gccaggtctc cactcgcacc gaaaattgta acaataacct tagatgacat ctagctacct
    57241 aatttctatt tttattccta gtcttgctag gtatgaggaa acctcatttc ataaacttaa
    57301 ttctaacata attttccgaa aaatcaaaaa ttccaatacg aggtagaaaa actgcaagga
    57361 aatccttaca gtttgagttt agacgtttaa gaccttatct aagaactctt tcagacgagg
    57421 gtgttgtggg ttatcaaaga tttggtcagg tgttccgtct tcaaggaact cgccatctgc
    57481 agtaaagata acgcggttgg caacctgacg agcaaatccc atctcatggg ttacgataat
    57541 catggtcatg ccttgctcag ccaattcctt cataacgtta agtacgtctc caaccatctc
    57601 agggtcaagg gcagaagttg gttcatcgaa gagcatgatg tctggattca ttgctaggcc
    57661 acgagctatg gccacacgtt gtttttgacc acctgatagg ctatctggat tggcattagc
    57721 tttatctgct agtccaacct tttcaagcaa ctccattccc aatttctcag cttcttcctt
    57781 agtcatcaac ttgtgctcaa taggagcaaa ggtgatgttg tccaatacag acatatgagg
    57841 gaagaggttg aagtgttgga ataccatgcc gatattttca cggacgtggt caacattggt
    57901 tgttttttca gttaaatcat agccgttcac agtgatgtga ccgctagtga cttcttctaa
    57961 aagattgagg ctacggagga aagttgactt accagaacct gaaggaccga tgatacaaac
    58021 aacatctcct tcatagaact tagtcgtaat tccttttagg acttcatttt ttccatagtg
    58081 cttgtgtaaa tcatttacat caatttttaa ttttgccatt aacgaatcct cttttctaag
    58141 cgtttcgcta gtctagtcaa aagtgtgata attacaagat agaagatagc aaggattgca
    58201 tacatcttga aactttggta gttacgagca atgataatct taccagtttg gaagagttca
    58261 accaaaccga tagcagatac gatagttgta tctttaagag cgataacgaa ttggttgaca
    58321 aagtttggca acatcaattt agttgcttgt ggcaagataa tcttacgcat ggtttttcca
    58381 taagagatac ccaagcttcg gctggcttcc atttggccaa ctggaacggc ctgaatacca
    58441 ccacgaacga tttcagcgat ataagcagcc gcattgagtg agagggcaat tgttccagct
    58501 acaaagtcgt taattgggct ttgttggcct gtgatagact cgatgaagtt tggaattccc
    58561 cagaagatga aggctgcaag aatcatcaat ggaataccac gaataacgtc aacgaaaatc
    58621 tcagagatga cgcgaagaga tttgtatggg ctaacgctaa acataccgaa gataattccg
    58681 atgacaatgg caatagcaaa tgagataaga gctagagcaa gagtgatacc aagaccgcta
    58741 aggagttgtt tgtagttgtt ttgaagcaag ccccagagcg ttgtttcgtc aacagtactt
    58801 gttgaagcag ttgaagattc gctagctagg tatttgtcaa gaatcttttg gaattcaccg
    58861 tttgctttaa ggtttgcaag tccgttgttg aacatttcaa tcagttctgg atttgctcct
    58921 tttttaacgg caaaggctgt ttcaccgatt ggagttccag agattggagt tttcaatttt
    58981 tgaccttggc tgatagaata tttgagaaca ggttcatcat ccataacggc atcaatggca
    59041 ccagtgttta aactgtcata cattgaagaa ccatcagcaa aggttttgat tttgtagccg
    59101 tatttgcttt gattttctgt taggaaggtt tgagaagcag ttccgttttt aacaccgact
    59161 gtctttcctt ttagatcttc ataagaagca atattacttg attctttgac accaagaatg
    59221 gtattagcag tgtagtatga ttctgagaag tcaaaagttg ccttacgagc atctgtgaca
    59281 gacataccag cgatgatacc atcggcttga ccagcttgga cagcactgat agcagcatca
    59341 aaaccagggt tggtgatttc aatttcaaaa ccttggtctt tagcgattgc cttaatcaat
    59401 tccatatcaa taccagtgta ttggttgctt gaattttgga aaacaaaagg ggcaaaagaa
    59461 gaatcgctgg caatgatata tttagcctta acaggaatag cttttaatcc tgcgagagta
    59521 gttgtagttg gcactgctga agatgatgaa gcagtccatt tcttgataat tttatcaaga
    59581 ctaccatctt ttttcatttc agacaaggct tggttaaatt cagtaaccag gtgctcgtat
    59641 ttacttcctt ttttcacacc gaaagcaaaa cttcctacag cttcaccatc catttcaata
    59701 tggaggtctt gaccttggtt aatggcatat tcgataacag gtttgtcatc catcatggca
    59761 tcgatggcac cagcactcaa gctgttgttc attaaatcac cagtgtcaaa tgttttaata
    59821 gtaaagccat atttatcttt gattgtttca aggaaacgtt gagcggcagt tccgttttta
    59881 acaccaacgg ttttgccagt taattggtcg tacttgctaa ttttgtgtga ctttgtagta
    59941 gcaatgacaa cttttgtatc atagtaagta tcagacatgg tgaagacttt ttcacgttct
    60001 ttagtctttg tcatccctgc catgatagcg tcggcttgcc cagcttgaac cgcattgact
    60061 gctgcgtcaa atccaggata ggacatctga atgttccagc ctttaatctc agcgactttg
    60121 ttaataatgt caacatcaat tcctttataa gtttgatctg aatctttaaa ctcaaaaggt
    60181 gcataggcgg tatcagaaac aatcttaatc gtttctgctt tggcaatacc taatgagaaa
    60241 attgggaata aaattagcaa aaatgctaga aattttttct tcatttttag tctccttttc
    60301 cgaatattct ctcattatat cagaaaaagt aaaaaaaggc aaatttttat atttttcgtg
    60361 tcagaaaata taacattgat ttttcctttt ctttcttgaa ttgctattaa aaagtgctat
    60421 aataatagta tatatagaag aaaagaggac ggggatatga agaacaaaag aatatttaaa
    60481 gacttccaag cttcaaaaat gagtttaaac atttacacaa gccccttgtt agcctttgtt
    60541 tttgtcttca taggagagtt tgtggctttt actttgtatg gtattggctt gttagctctc
    60601 atcggacttg ctagaaattt tggagaggct ggtcaaaatc ttgcaaccta cttgcagacc
    60661 ttgcatcaga gcttgacgga taaaacaagt gactttcgtt taattttagg attactggcc
    60721 tttggtttta ttcttaacac tgtgttcaga tggacaagaa aagttgagaa aagacctatt
    60781 cgaaccttgg gattttatag agagaatttc ctcagcaatc ttctgaaagg atttagtcta
    60841 ggcttggcac tttttcttct gaccttgtta ggtttagtgg tcttaggtca atatcgtttg
    60901 gaatccattc acttgaatcc ttattctctt gcctttgtcg tctttactat cccattttgg
    60961 attttacagg ggacagcaga agaagtggtg gcccgtgctt ggctacttcc tcaattggcc
    61021 tcaagaacca atctaaaact agctattctt atatctagcc tgttctttac cctgcttcat
    61081 atgggcaatt ctggcctcac ccctctatct ctagtaaatc tctttttatt cggagttgcc
    61141 atggctcttt atcttctcaa aactgataca gtttggggtg ttgcaggtat tcatggtgct
    61201 tggaattttg ctcagggtaa tctctttggg attttagtta gtggtcaacc gtcaggaacg
    61261 tctctgatga cctttttacc acaaggcaat caagattggc tatcaggtgg ttcttttggc
    61321 atagaaggtt ccattatgac aagtctggta ttactactgc tgattgtcta tcttgctaat
    61381 aaattaaaga aagaaaatga aaggatgtga cttcggtccg tccttttctt cgtgaaaata
    61441 ctataagtat gctaaaatag gaatagcaca tggagagagg attcttatga tcaatcacat
    61501 tacagataat caatttaaac tagtatcaaa atatcaacca tcaggagatc aaccccaagc
    61561 tatcgagcag ttggtggata acattgaggg gggagaaaaa gctcagattc tgatgggggc
    61621 gactggaaca gggaagacct atactatgag tcaggtcatt tctaaagtca ataaaccaac
    61681 tctggttatt gcccacaata aaactctggc tggtcagctc tatggggagt ttaaggaatt
    61741 tttccctgaa aatgcagttg agtatttcgt atcctactat gattattacc agccagaggc
    61801 ctatgtccct tctagcgata cctatattga gaaggatagt tctgtcaatg acgagattga
    61861 caagcttcgc cactcagcta cctcagccct tttggagcgt aatgatgtta ttgtcgtggc
    61921 ctcagtctct tgtatctatg gtttgggttc gcccaaggaa tacgctgata gtgtcgttag
    61981 tctccgtcct ggtctagaga tttctcgtga taaactcttg aatgacttgg tcgatattca
    62041 gtttgaacgt aatgatattg atttccaacg cggaagattt cgcgttcgtg gggatgtggt
    62101 agagattttc ccagcttccc gagatgaaca tgcctttcga gtagaatttt ttggagacga
    62161 aattgaccgt atccgtgagg ttgaggctct gacaggtcag gtattgggag aggtggatca
    62221 tttggcgatt ttcccagcta ctcactttgt gaccaatgac gaccatatgg aagttgccgt
    62281 tgccaagatt caagcagaat tagaagagca gttagctgtc tttgaaaagg aaggtaaact
    62341 gcttgaagcc cagcgtttga aacagcggac agagtatgat atcgaaatgt tgcgtgagat
    62401 gggctatacc aatggggttg aaaattattc tcgccacatg gatggacgga gcgaaggaga
    62461 gcctccttat acgcttctcg acttcttccc agatgatttc ttgattatga ttgacgagag
    62521 tcatatgacc atagggcaaa tcaagggcat gtacaatgga gaccgttcgc gtaaggaaat
    62581 gctagtaaat tatggtttcc gtttaccgtc tgccttggac aatcgtcctc tccgtcgtga
    62641 ggagtttgaa agccatgtgc atcagattgt ttacgtatca gcgacacctg gtgactatga
    62701 aaatgaacag actgagacgg tgattgagca aatcattcga ccgacagggc ttttggatcc
    62761 tgaggtggaa gtccgtccga ctatgggaca gattgatgat ctcttaggtg aaatcaatgc
    62821 ccgtgttgaa aagaatgaac gaacctttat caccaccttg accaagaaaa tggcagagga
    62881 cttgaccgac tatttcaagg aaatgggcat caaggtcaag tacatgcact cggatatcaa
    62941 gaccttggaa cggacggaga ttatccgtga tctccgcttg ggtgtctttg atgtcttggt
    63001 tggaatcaat ctccttcgtg aagggattga cgttcctgag gttagcttgg ttgccattct
    63061 cgatgctgac aaggaaggtt tccttcgtaa cgagcgtgga ctcatccaga ccattgggcg
    63121 tgccgcccgt aacagtgaag gtcatgtcat catgtatgca gatacggtta cccagtctat
    63181 gcaacgtgct atcgatgaaa ctgcccgccg tcggaaaatt cagatggcct ataatgaaga
    63241 gcatggtatc gtaccacaga caatcaagaa agaaatccgt gacctgattg ccgtgaccaa
    63301 ggcagttgct aaggaagagg acaaggaagt cgacatcaat agcctcaaca aacaagagcg
    63361 caaagaactc gtcaagaaac tagaaaaaca aatgcaagaa gccgtcgaag tgcttgactt
    63421 tgaactggcg gctcagatcc gtgatatgat gttggaagtc aaggccttgg attaggggaa
    63481 tagtatgatt tatttaagaa agttaaagaa agaagatttg atgtctttat gggaaatggc
    63541 ttattcacag cttaatccag tttggaaaca gtatgatgct ccctattatg atgattatca
    63601 gtatttttca aattttaaag aattcgaact acaaaaatca gaatccattt taagcaactc
    63661 aaatcgcctt ggtatttttg ttgatgataa actagttggg actgtttcgc gttattgggt
    63721 atgtaaagaa acaagatgga tggaattggg aattggtatt tatgataaaa aattctggaa
    63781 cactggtatt gggaaagttg ctatgttgca gtggatagat aggacgtttc aggattactt
    63841 ggagttggag catctgggtt tgacaacttg gtcagggaat cttggtatga tgaaacttgc
    63901 tgaaaaatta agaatgaaaa aagaagctca tattccaaaa gttcgttatt atcaaggtaa
    63961 atattttgat agtattaaat atggtatttt gagagaagac tgggagaaaa taaatgacgg
    64021 ttattatcaa atcaatggaa actcctgaag agatagaagg taaatccctc gttcactggc
    64081 aaacgtggag agaggcttat gatgaccttt tgcctgcaga atttcaggag acaatgacat
    64141 tagaaagatg tcgattcttt agtcaaaagt atccagaaaa tacattgatt gcgataggtg
    64201 atctgaaggt agttggtttt atcagttatg gtaactttcg tgatgatact attcaagctg
    64261 gtggaattat tgctttatat gttttaaaag actattacgg aaaaggcata gcacaaaagt
    64321 taatgaaagc agctttgact gctcttaatc atttttctga aattttctta tgggtattga
    64381 aagataacaa gcgcgccatt gctttctatc aaaaaatggg ttttactttt gatggacaag
    64441 aaaaaatact tgaacttgga aagcctataa aggaaaaacg aatggtgttc tattctaaat
    64501 aattttaaaa aagtaaaaga taatatctct ggtagtaagt ctgaaaattt aataaattag
    64561 aaagcgagta aatttatgtc ccgttcccaa ttaacaattt taacaaatat ctgtctgatt
    64621 gaagacctcg aaacgcagcg cgtggtgatg cagtatcgcg cccctgaaaa caatcgctgg
    64681 tctggttatg cctttcctgg aggtcatgta gaaaatgatg aggcttttgc ggagtctgtc
    64741 attcgtgaaa tctacgaaga aacagggttg actatccaaa atcctcaact tgtcggcatt
    64801 aaaaattggc cactagatac aggtgggcgc tatattgtca tttgttataa ggcgactgag
    64861 ttctctggta cccttcaatc ttcagaagag ggagaagttt cttgggtgca aaaagaccag
    64921 attccaaact taaatctggc ctatgatatg ctaccattga tggaaatgat ggaagctccc
    64981 gacaagtcag agtttttcta ccctcgccgt acagaagacg attgggaaaa gaaaatcttc
    65041 tagtctttta ctaaataacc tagctgatcc aaggcctcct cgatatagtg gaggtcttgt
    65101 tgtgtttcgg cttcgactag gtggtaatgg atgccatctg tcaattcaga tagaggtcta
    65161 aagtcagaat gctcgacttg ttctagaaaa tgttgcacat ctctgcgaca agacagttta
    65221 agcaaggttt caatttctcc ataaacggga tggtcaatca aggtattctg gacatgccca
    65281 ccattatcga caatagcaag gagttcctga ccgatttctt caacttcatg tttcactttg
    65341 aaaagtttgt gaacataagg attggtatca atttgcttat agatgtagcc acgattggtg
    65401 gataggatag gagcgccatc ggctctcaaa attgcaatgt cctgcacaat gacctgacgt
    65461 gtgacatgaa aatgttccgc caaactttgg ccattaaggg ctttaggagc ttctttcaag
    65521 agttggagca gggcttgttt gcgatctttt gtcatagctt ttccttttaa cggcgttttc
    65581 gaagcacttt atagacagct agtgctaatg tatagtctac catactatgg ataattgtgc
    65641 caaatccaac tagtacaaat agaacataga acatgttttc tacattggta cccgaagttg
    65701 cgtaaaaaag gacacaggct aatacttcag caagggcatg aacaacagcc aaaacaaaat
    65761 tgaaaaccca ggaagatttt ggtttatcta gggtatcggg gaatttttgt aggtaaagag
    65821 ctcctaaagc accaaaagat atatgggaaa aagcccgaaa aacgataacc atgggatagc
    65881 cagccatcaa aaatccaaaa ctagaggcta ggatgacaaa aactgccatc aagggcgaca
    65941 agaacatggc tataaaaata gcgatgtggc tccccaaagt ataggaagca ggtggaatga
    66001 caatcttgaa aggcataaca attggaatca aaatcgcaat agccgttaaa agggctgtca
    66061 ttgtcataaa ttgtgtcttt ttccgtgtat tcacaagaat ctccttttta actgcatata
    66121 cactagtatg gtacaataaa ccagacaata aagcaagaat ttacttgggt ttatagatca
    66181 ttttttagtt aaaagttata gtagattgaa act
//
LOCUS       DAVBOD010000005        63603 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 640-05
            SAMEA1012484-rid20186543.denovo.005, whole genome shotgun sequence.
ACCESSION   DAVBOD010000005 DAVBOD010000000
VERSION     DAVBOD010000005.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012484
            Sequence Read Archive: ERR059358
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 63603)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 63603)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979948.1
            Genome Coverage       :: 595x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:03:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,266
            CDSs (total)                      :: 2,219
            Genes (coding)                    :: 2,091
            CDSs (with protein)               :: 2,091
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 71 of 128
            Pseudo Genes (incomplete)         :: 50 of 128
            Pseudo Genes (internal stop)      :: 33 of 128
            Pseudo Genes (multiple problems)  :: 22 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..63603
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012484-rid20186543.denovo.005"
                     /strain="NIG 640-05"
                     /db_xref="taxon:1313"
     gene            complement(1..750)
                     /locus_tag="VQ862_000288"
                     /pseudo
     CDS             complement(1..750)
                     /locus_tag="VQ862_000288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000567576.1"
                     /note="internal stop; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="epoxyqueuosine reductase QueH"
     gene            complement(888..2510)
                     /gene="groL"
                     /locus_tag="VQ862_000289"
     CDS             complement(888..2510)
                     /gene="groL"
                     /locus_tag="VQ862_000289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018166362.1"
                     /note="60 kDa chaperone family; promotes refolding of
                     misfolded polypeptides especially under stressful
                     conditions; forms two stacked rings of heptamers to form a
                     barrel-shaped 14mer; ends can be capped by GroES;
                     misfolded proteins enter the barrel where they are
                     refolded when GroES binds; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chaperonin GroEL"
                     /protein_id="HET3114696.1"
                     /translation="MSKEIKFSSDARSAMVRGVDILADTVKVTLGPKGRNVVLEKSFG
                     SPLITNDGVTIAKEIELEDHFENMGAKLVSEVASKTNDIAGDGTTTATVLTQAIVREG
                     IKNVTAGANPIGIRRGIETAVAAAVEALKNNAIPVANKEAIAQVAAVSSRSEKVGEYI
                     SEAMEKVGKDGVITIEESRGMETELEVVEGMQFDRGYLSQYMVTDSEKMVADLENPYI
                     LITDKKISNIQEILPLLESILQSNRPLLIIADDVDGEALPTLVLNKIRGTFNVVAVKA
                     PGFGDRRKAMLEDIAILTGGTVITEDLGLELKDATIEALGQAARVTVDKDSTVIVEGA
                     GNPEAISHRVAVIKSQIETTTSEFDREKLQERLAKLSGGVAVIKVGAATETELKEMKL
                     RIEDALNATRAAVEEGIVAGGGTALANVIPAVATLELTGDEVTGRNIVLRALEEPVRQ
                     IAHNAGFEGSIVIDRLKNAELGIGFNAATGEWVNMIDQGIIDPVKVSRSALQNAASVA
                     SLILTTEAVVANKPEPVAPAPAMDPSMMGGMM"
     gene            complement(2526..2810)
                     /gene="groES"
                     /locus_tag="VQ862_000290"
     CDS             complement(2526..2810)
                     /gene="groES"
                     /locus_tag="VQ862_000290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="co-chaperone GroES"
                     /protein_id="HET3114697.1"
                     /translation="MLKPLGDRVVLKIEEKEQTVGGFVLAGSAQEKTKTAQVVATGQG
                     VRTLNGDLVAPSVKTGDRVLVEAHAGLDVKDGDEKYIIVGEANILAIIEE"
     gene            complement(3080..3475)
                     /locus_tag="VQ862_000291"
     CDS             complement(3080..3475)
                     /locus_tag="VQ862_000291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000282444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HET3114698.1"
                     /translation="MYNKVIMIGRLTSTPELHKTNNDKSVARATIAVNRRYKDQNGER
                     EADFVNMVLWGRLAETLASYATKGSLISVDGELRTRRFEKNGQMNYVTEVLVTGFQLL
                     ESRAQRAMRENNAGQDLADLVLEEEELPF"
     gene            complement(3553..4314)
                     /locus_tag="VQ862_000292"
     CDS             complement(3553..4314)
                     /locus_tag="VQ862_000292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HET3114699.1"
                     /translation="MAKNVVITGATSGIGEAIARAYLEQGEDVVLTGRRIDRLEILKS
                     EFAVSFPNQTVWTFPLDVTDMVMVKTVCSDILETIGRIDILVNNAGLALDLAPYQDYE
                     ELDMLTMLDTNVKGLMAVTRCFLPAMIKVNQGHIINMGSTAGIYAYAGAAVYSATKAA
                     VKTFSDGLRIDTIATDIKVTTIQPGIVETDFSTVRFHGDKERAASVYQGIEALQAQDI
                     ADTVVYVTSQPRRVQITDMTIMANQQATGFMIHKK"
     gene            complement(4347..4973)
                     /locus_tag="VQ862_000293"
     CDS             complement(4347..4973)
                     /locus_tag="VQ862_000293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4479 and tRNA-binding domain-containing
                     protein"
                     /protein_id="HET3114700.1"
                     /translation="MIFTYNKEHVSDVLMVIVKNSGDAKLNVERKGKVARVFLKENGE
                     TVAWNIFEVSSLFEIAERGQVFLSDEQVARLNQELQAEGFTEEIVNDKEPKFVVGEIV
                     EMVAHPDSDHLNICQVAVASDKIVQIVAGAPNARVGLKTIVALPGAMMPKGNFIFPGE
                     LRGEKSFGMMCSPRELHLPNAPQKRGVLELSEDQVVGTPFDPAKHWTA"
     gene            complement(4989..5306)
                     /locus_tag="VQ862_000294"
     CDS             complement(4989..5306)
                     /locus_tag="VQ862_000294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000615765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HET3114701.1"
                     /translation="MIQPASLEELASLVEKAGKKVFLFVADWCGDCRYIYPALPEIEE
                     TNPEFTFIRMDRDQYMDLAKLWDVYGIPSLVVLEKDKEIGRFVNRDRKSKEQINDFLA
                     GLK"
     gene            complement(5303..5602)
                     /locus_tag="VQ862_000295"
     CDS             complement(5303..5602)
                     /locus_tag="VQ862_000295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001013971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4651 domain-containing protein"
                     /protein_id="HET3114702.1"
                     /translation="MNGMKAKKMWMAGLALLGIGSLALATKKVADDRKLMKTQEELTE
                     IVRDHFSDMGEIATLYVQVYESSLESLVGGVIFEDGRHYTFVYENEDLVYEEEVL"
     gene            complement(5887..6078)
                     /locus_tag="VQ862_000296"
     CDS             complement(5887..6078)
                     /locus_tag="VQ862_000296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000291825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein"
                     /protein_id="HET3114703.1"
                     /translation="MYYSVDDVVSNAFKKRMILDSFFAFNCSGTMKVSTWVYDKGEWY
                     YVSSSGSMIANDWVKDNGK"
     gene            complement(6239..6913)
                     /locus_tag="VQ862_000297"
     CDS             complement(6239..6913)
                     /locus_tag="VQ862_000297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3114704.1"
                     /translation="MKKKAFGIVLLVLAALILVQGNFGIPSLGGHIWPLIGIAFFAYQ
                     SVGALLRRHLTSASFTALVALMIANHFYGILPIPNQTLIWAGVLIVLGVNMLTHSNRT
                     WNGKKWWYDGEKNILIDKEVAFGTGTFYKQDQELVEDQVEVGFGNAKIYYDNAEMLGD
                     FATLNIEVAFGNATVYVPQHWRVDLKVETSFGAAKADAPVAPTSKTLIIRGDVAFGKL
                     EIVYAK"
     gene            complement(6918..7364)
                     /locus_tag="VQ862_000298"
     CDS             complement(6918..7364)
                     /locus_tag="VQ862_000298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000776610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET3114705.1"
                     /translation="MKLRIEIDGNLEETEIVIKTPTLTDEIADLQRLLQESKSPRLIF
                     YKGTGEYYLDLSEILFFETEGSKIYAHTQKNAYEVRLKLYELEAILPRYFSRVSKSTI
                     VNIRQIYSVDKSFSGTGTISFYQTHKEVHVSRHYQSLLKENLRNMR"
     gene            complement(7478..7981)
                     /locus_tag="VQ862_000299"
     CDS             complement(7478..7981)
                     /locus_tag="VQ862_000299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000800945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HET3114706.1"
                     /translation="MKNYQEWYRNIRSRLTSRPILLFLLRSFNRLMTVAMPLVYLILL
                     VTTYLQLGLGQQVGVYVLIPASGFVALSLFRKKINHPRPYETWDICPLLDKDSSGRSM
                     PSRHVFSATIISMACLHASLPIGLVCLIFSALLGLVRVLGGVHYPKDVLVGYACGLVW
                     GFLFFLF"
     gene            complement(7978..8340)
                     /locus_tag="VQ862_000300"
     CDS             complement(7978..8340)
                     /locus_tag="VQ862_000300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2200 domain-containing protein"
                     /protein_id="HET3114707.1"
                     /translation="MSQKLYNMKFAAVYLALIAKVERKGGKAESVHQVTSWLTGYEVS
                     DVLTCLDRDVTYGDFFRQAPYYVPERIAITGKICGVRIEEIDDPLMQEIRRLDKLVDW
                     LAKGKTSQQVLEKYEKHK"
     gene            complement(8466..10265)
                     /locus_tag="VQ862_000301"
                     /pseudo
     CDS             complement(8466..10265)
                     /locus_tag="VQ862_000301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001850459.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein/permease"
     gene            complement(10282..10751)
                     /locus_tag="VQ862_000302"
                     /pseudo
     CDS             complement(10282..10751)
                     /locus_tag="VQ862_000302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000360543.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
     gene            complement(10875..11591)
                     /locus_tag="VQ862_000303"
     CDS             complement(10875..11591)
                     /locus_tag="VQ862_000303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015604432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HET3114708.1"
                     /translation="MGRKWANIVAKKTAKDGANSKVYAKFGVEIYVAAKKGDPDPESN
                     SALKFVIDRAKQAQVPKHIIDKAIDKAKGNTDETFTEGRYEGFGPNGSMLIVDTLTSN
                     VNRTAANVRAAFGKNGGNMGASGSVSYLFDNKGVIVFGGEDADAVFEQLLEADVDVDD
                     VEAQEGTITVYTAPTDLHKAIVALRESGIEEFQVTELEMIPQSEVELSGEDLETFEKL
                     YSVLEDDEDVQKIYTNVDGF"
     gene            complement(12472..13887)
                     /gene="ply"
                     /locus_tag="VQ862_000304"
     CDS             complement(12472..13887)
                     /gene="ply"
                     /locus_tag="VQ862_000304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cholesterol-dependent cytolysin pneumolysin"
                     /protein_id="HET3114709.1"
                     /translation="MANKAVNDFILAMNYDKKKLLTHQGESIENRFIKEGNQLPDEFV
                     VIERKKRSLSTNTSDISVTATNDSRLYPGALLVVDETLLENNPTLLAVDRAPMTYSID
                     LPGLASSDSFLQVEDPSNSSVRGAVNDLLAKWHQDYGQVNNVPARMQYEKITAHSMEQ
                     LKVKFGSDFEKTGNSLDIDFNSVHSGEKQIQIVNFKQIYYTVSVDAVKNPGDVFQDTV
                     TVEDLKQRGISAERPLVYISSVAYGRQVYLKLETTSKSDEVEAAFEALIKGVKVAPQT
                     EWKQILDNTEVKAVILGGDPSSGARVVTGKVDMVEDLIQEGSRFTADHPGLPISYTTS
                     FLRDNVVATFQNSTDYVETKVTAYRNGDLLLDHSGAYVAQYYITWDELSYDHQGKEVL
                     TPKAWDRNGQDLTAHFTTSIPLKGNVRNLSVKIRECTGLAWEWWRTVYEKTDLPLVRK
                     RTISIWGTTLYPQVEDKVEND"
     gene            complement(13898..14230)
                     /locus_tag="VQ862_000305"
     CDS             complement(13898..14230)
                     /locus_tag="VQ862_000305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3114710.1"
                     /translation="MYICIDNSMTKNKELVKNQTFKPALLTRRLVKNFMIEEPDLARN
                     PFTRPTLIDLDKVFMLDNTVIPTSYLARRRRNVSEELYEEILDHLVQPRLISLNKSEF
                     MQLNPGTY"
     gene            complement(14301..14909)
                     /locus_tag="VQ862_000306"
     CDS             complement(14301..14909)
                     /locus_tag="VQ862_000306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000083609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3114711.1"
                     /translation="MSQSSYLSPLLWLKKEADKEKMSATQCQIFFFYYQMFELLFARE
                     SDMKDLCLGTKGFYFSQLEKNLLSGVSRFLKNLEGKVTLKANQEVSARKALFLALTTS
                     QSDWQELAPVFDFYQTIGRLENPSLLSSQDRQHLMWIYQSALEKDYIVKVIGDKHFVL
                     KRQDATKLTARQTQTLEILSQSEDLVNPVYVTLGEKGVLLLD"
     gene            complement(14922..15380)
                     /locus_tag="VQ862_000307"
     CDS             complement(14922..15380)
                     /locus_tag="VQ862_000307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000186958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4231 domain-containing protein"
                     /protein_id="HET3114712.1"
                     /translation="MTPEEMYLTERLDVQIAHFLKKSVQHRRRYKVLKITEIVAGFLI
                     AVFCAIPMPGDRYRLISVALSSLGLLCEGIINLYNAKENWISYQKTAQLLEKEKFLYQ
                     CQTEKYAGKTKAFALFVKTCEGLISEEINQWESIQSKEVAASADAPVKKE"
     gene            15505..15904
                     /locus_tag="VQ862_000308"
                     /pseudo
     CDS             15505..15904
                     /locus_tag="VQ862_000308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(16669..16929)
                     /locus_tag="VQ862_000309"
     CDS             complement(16669..16929)
                     /locus_tag="VQ862_000309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3114713.1"
                     /translation="MRERSATGAQGLSKSIKKHLNDLTRLTASLLGDEKLSAITSSSA
                     VKADMHRFVIELELVKSTILQNDDISLDQNEIFEILKNFFDG"
     gene            complement(16988..17539)
                     /locus_tag="VQ862_000310"
     CDS             complement(16988..17539)
                     /locus_tag="VQ862_000310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001111259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3114714.1"
                     /translation="MPANTKVIFQEMFADFQNYYVLIGGTATSIVLDSQGFKSRTTKD
                     YDMVIIDEVKNKEFYTTLNHFLELGEYQGSQKDEKAQLFRFTTTNSEFPSMIELFSIL
                     PEYPLKKDGREIPLHFDQDASLSALLLDEDYYNILVHEKETIQGYSVLSNCGLYSSKI
                     SSNHVSFHLQPQNSVLSSLQLAS"
     gene            complement(17529..17726)
                     /locus_tag="VQ862_000311"
     CDS             complement(17529..17726)
                     /locus_tag="VQ862_000311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000890145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3114715.1"
                     /translation="MLEIWKYRPFVSEFWNDFKNNHDKQFVDPISLYLTLKDDDDPRI
                     EEESEALENMILQYLGEDDAS"
     gene            complement(17730..18314)
                     /locus_tag="VQ862_000312"
     CDS             complement(17730..18314)
                     /locus_tag="VQ862_000312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001101186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3114716.1"
                     /translation="MNVKKIMSIFQSFYVDVSIEELTLTLPISFVKKFEYTQMTFHKE
                     SFLLIKEKRRGSLSSFVTQARTMGDKANMDVVLVFSKLSDGEKKQLLQARVPFVDFKG
                     NLFFPTLGLVLNANDTEVPKELIPSEQLTWIAFLLPDGDIKQIKSVSNLLYGGAYALS
                     HSTFLAETDENTSYVIWQRKFNQLSLPLSQHVLK"
     gene            complement(18712..19137)
                     /locus_tag="VQ862_000313"
     CDS             complement(18712..19137)
                     /locus_tag="VQ862_000313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000204059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3114717.1"
                     /translation="MTSRVFIDADCISVFLWVGIEHLLEKLYLGKIVIPQEVYDEINI
                     PTIPHLKSRIDQLVAKGSAEIVSIDIGTEEYALYRDLTRNHDSNKIIGKGEGASISLA
                     KKHNGILGSNNLRDVKPYVEEFSLEHMTTGDILIEAFKA"
     gene            complement(19266..19625)
                     /locus_tag="VQ862_000314"
     CDS             complement(19266..19625)
                     /locus_tag="VQ862_000314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000749821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3114718.1"
                     /translation="MKKSSVSLILIGEGDETERKADQFASYFLIFPSSLYRMVEEIRE
                     NANRTHLEVEDIIKLGQFYGISHKAMLYRLRNDGYLDAEEIKNMDISVIETASRLGYD
                     TSLYRPLSESKKEMALG"
     gene            complement(19671..19877)
                     /locus_tag="VQ862_000315"
     CDS             complement(19671..19877)
                     /locus_tag="VQ862_000315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000366086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3114719.1"
                     /translation="MDLSNKASNLRKKLGADGESPIDIFKLVQKIENLTLVFYGLGKN
                     ISGVCYKGTQFSLIAVNSDMPLER"
     gene            complement(19864..20025)
                     /locus_tag="VQ862_000316"
     CDS             complement(19864..20025)
                     /locus_tag="VQ862_000316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000289348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET3114720.1"
                     /translation="MYVINVCDVGKRIKELRISSNLTQDKIAEYLSLNQSMIAKMEKG
                     ERNITNGFK"
     gene            complement(20384..21340)
                     /gene="lytA"
                     /locus_tag="VQ862_000317"
     CDS             complement(20384..21340)
                     /gene="lytA"
                     /locus_tag="VQ862_000317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase LytA"
                     /protein_id="HET3114721.1"
                     /translation="MEINVSKLRTDLPQVGVQPYRQVHAHSTGNPHSTVQNEADYHWR
                     KDPELGFFSHIVGNGCIMQVGPVDNGAWDVGGGWNAETYAAVELIESHSTKEEFMTDY
                     RLYIELLRNLADEAGLPKTLDTGSLAGIKTHEYCTNNQPNNHSDHVDPYPYLAKWGIS
                     REQFKYDIENGLTIETGWQKNDTGYWYVHSDGSYPKDKFEKINGTWYYFDSSGYMLAD
                     RWRKHTDGNWYWFDNSGEMATGWKKIADKWYYFNEEGAMKTGWVKYKDTWYYLDAKEG
                     AMVSNAFIQSADGTGWYYLKPDGTLADKPEFTVEPDGLITVK"
     gene            complement(21716..23086)
                     /locus_tag="VQ862_000318"
     CDS             complement(21716..23086)
                     /locus_tag="VQ862_000318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001036275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HET3114722.1"
                     /translation="MNKKRTVDLIHGSILPSLLSFTFPILLSNIFQQLYNTADVLIVG
                     RFLGQESLAAVGATTAIFDLIVGFTLGVGNGMGIVIARYYGARNFTKIKEAVAATWIL
                     GALLSILVMLLGFLGLYPLLQYLDTPAEILPQSYQYISMIVTCVGVSFAYNLFAGLLR
                     SIGDSLAALGFLIFSALVNVVLDLYFITQLHLGVQSAGLATIISQGLSAVLCFYYIRK
                     SVPELLPRFKHFKWDKSLYADLLEQGLAMGLMSSIVSIGSVILQFSVNTFGAVIISAQ
                     TAARRIMTFALLPMTAISASMTTFASQNLGAKRPDRIVQGLRIGSRLSISWAVFVCIF
                     LFFASPALVSFLASSTDGYLIENGSLYLQISSAFYPILSLLLIYRNCLQGLGQKILPL
                     VSSFIELIGKIVFVVLIIPWAGYKGVILCEPLIWVAMTVQLYFSLFRHPLIKEGKAIL
                     ATKVQS"
     gene            complement(23393..24559)
                     /gene="recA"
                     /locus_tag="VQ862_000319"
     CDS             complement(23393..24559)
                     /gene="recA"
                     /locus_tag="VQ862_000319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecA"
                     /protein_id="HET3114723.1"
                     /translation="MAKKPKKLEEISKKFGAEREKALNDALKLIEKDFGKGSIMRLGE
                     RAEQKVQVMSSGSLALDIALGSGGYPKGRIIEIYGPESSGKTTVALHAVAQAQKEGGI
                     AAFIDAEHALDPAYAAALGVNIDELLLSQPDSGEQGLEIAGKLIDSGAVDLVVVDSVA
                     ALVPRAEIDGDIGDSHVGLQARMMSQAMRKLGASINKTKTIAIFINQLREKVGVMFGN
                     PETTPGGRALKFYASVRLDVRGNTQIKGTGDQKETNVGKETKIKVVKNKVAPPFKEAV
                     VEIMYGEGISKTGELLKIASDLDIIKKAGAWYSYKDEKIGQGSENAKKYLAEHPEIFD
                     EIDKQVRSKFGLIDGEEVSEQDTENKKDEPKKEEAVNEEVTLDLGDELEIEIEE"
     gene            complement(24614..25870)
                     /locus_tag="VQ862_000320"
     CDS             complement(24614..25870)
                     /locus_tag="VQ862_000320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000642700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence/damage-inducible protein A"
                     /protein_id="HET3114724.1"
                     /translation="MKAEIIAVGTEILTGQIVNTNAQFLSEKLAEIGVDVYFQTAVGD
                     NEVRLLSLLEIASQRSSLVILTGGLGPTEDDLTKQTLAKFLGKALVFDPQAQEKLDIF
                     FALRPDYARTPNNERQAQIVEGAIPLPNETGLAVGGKLEVDGVTYVVLPGPPSELKPM
                     VLNQLLPKLMTGSKLYSRVLRFFGIGESQLVTILADLIDNQIDPTLAPYAKTGEVTLR
                     LSTKASSQEEANQALDILENQILDCQTFEGISLRDFCYGYGEETSLASIVVEELKRQG
                     KTIAAAESLTAGLFQATVANFSGVSSIFKGGFVTYSLEEKSRMLDIPAKNLEEHGVVS
                     EFTAQKMAEQARSKTQSDFGISLTGVAGPDSLEGHPVGTVFIGLAQEQGTEVIKVNIG
                     GRSRADVRHIAVMHAFNLVRKALLSD"
     gene            complement(25955..26971)
                     /locus_tag="VQ862_000321"
     CDS             complement(25955..26971)
                     /locus_tag="VQ862_000321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000239264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HET3114725.1"
                     /translation="MVKKIIGMVLALLSVTVVGVGVFAYTIYQQGTETLAKTYKKIGE
                     ETKVIEATEPLTILLMGVDTGNVERTETWVGRSDSMILMTVNPKTKKTTMMSLERDIL
                     TRIESGNGQAHEAKLNSAYADGGAELAIETIQKMMNIHIDRYVMVNMRGLQKLVDAVG
                     GITVNNILGFPISISDQEEFNTISIGVGEQHIGGEEALVYARMRYQDPEGDYGRQKRQ
                     REVIQKVMEKALSLNSIGHYQEILKALSDNMQTNIDLSAKSIPNLLGYKDSFKTIETQ
                     QLQGEGEILQGVSYQIVSRAHMLEMQNILRRSLGQEEVTQLETNAVLFEDLFGRAPVG
                     DEDN"
     gene            complement(26979..27497)
                     /locus_tag="VQ862_000322"
     CDS             complement(26979..27497)
                     /locus_tag="VQ862_000322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET3114726.1"
                     /translation="MEYELLIREAEPKDAAELVAFLNRVSLETDFTSLDGDGILLTSE
                     EMEIFLNKQASSDNQITLLAFLNGKITGIVNITADQRKRVRHIGDLFIVIGKRYWNNG
                     LGSLLLEEAIEWAQASGILRRLQLTVQTRNQAAVHLYQKHGFVIEGSQERGAYIEEGK
                     FIEVYLMGKLIG"
     gene            complement(27487..27930)
                     /gene="tsaE"
                     /locus_tag="VQ862_000323"
     CDS             complement(27487..27930)
                     /gene="tsaE"
                     /locus_tag="VQ862_000323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000288243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     ATPase subunit type 1 TsaE"
                     /protein_id="HET3114727.1"
                     /translation="MYIKNEEELQALGERLGHLLAKNDVLILIGELGAGKTTFTKGLA
                     KGLQISQMIKSPTYTIVREYEGRLPLYHLDVYRIEGDADSIDLDEFIFGGGVTVIEWG
                     NLLGDALPDAYLELEILKEADGRRLNFQAKGLRAEKLSEELQYGV"
     gene            complement(28016..28636)
                     /locus_tag="VQ862_000324"
     CDS             complement(28016..28636)
                     /locus_tag="VQ862_000324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000839915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3114728.1"
                     /translation="MKSMRILFLLALIQISLSSCFLWKECILSFKQSTAFFIGSMVFV
                     SGICAGVNYLYTRKQEVHSVLASKKSVKLFYSMLLLINLLGAVLVLSDNLFIKNTLQQ
                     ELVDFLLPSFFFLFGLDLLIFLPLKKYVRDFLAMLDRKKTVLVTILATLLFLRNPMTI
                     VSLLIYIGLGLFFAAYLVPNSVKKEVSFYGHIFRDLVLVIVTLIFF"
     gene            complement(29019..29882)
                     /locus_tag="VQ862_000325"
     CDS             complement(29019..29882)
                     /locus_tag="VQ862_000325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET3114729.1"
                     /translation="MNTLAEKFRLKRKELRLSQQTLAEGICEQSQISKIERGHFIPSA
                     DLLFKLSQRLEVPLDYFFNEQIEIKSNLSNFKQLSARLLDDRNYDDLEYIYRIEIERS
                     TFLTLEDRTYLEWIKAIIDFYQYDSKCEAISSLENILLKVSSNTLIYLKALNTLSNFY
                     SLVGREQEYEANYSHLIELYQTKNLDHQEFLFGYIRVRYNYAHYLVSKEKYNEAIQEA
                     LETIELCKQRQTSYQLAPLLILVGNAGAKFLDREQVKNYYIEARELCKIYNNPLMLMK
                     IENYLKELDTV"
     gene            30386..32401
                     /locus_tag="VQ862_000326"
     CDS             30386..32401
                     /locus_tag="VQ862_000326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HET3114730.1"
                     /translation="MKKLFILISNLLASLFFVWVFTIWTDTYVSYYYPNVVVHDSSPE
                     TTFQHVATRLEKLAEETDSFIAIQHQDSNSEGTTVFSYTTFGDGKLPDGLQEKKLEDA
                     QSSSVETNYFVFDGHLDIHLLREELSQLGLTNMNLTIPSKLSTLMAIFSNGFQLISLL
                     IFILTFVALTLISQISQLRSSGIRLISGEKRWSIFLRPVGEDLKGIAVGFSLAGVLAI
                     LMQKILSLPTQSLMTIGAGLLSYNLILLSISLFFAQLFAVGIKKIHLMQIIKGQVPVR
                     GIISLILIGQLLAIIIVTLGIGSSLKYSQAWQQHRIGQEAWSQERQLITLSISREGTS
                     PGFDEQAQRKLRTWYQLMDLAVSEQKAFLSRHQLIDRTLQNGMASSKNLITSTEWHDY
                     NPNGNVLIVTPQYLERQNIPVDTTIEQKMNHLYVGEFVLLLPEHLRSEEEHYKSVFED
                     DLTSRMSSQDERQQMTATVGYLESGQDRFVYNTTPISYQQFLKDPIIIVITPQSTGPQ
                     SILFWIDAVQNYVLFNQLSDAQELIQRQGIENWVSEMQTGYHNYITLLDNIQRERWVM
                     LAGAGLGIATSILLFNTMNRLYFEEFRRAIFIKRIAGLRFLEIHRTYLFAQLGVFLLG
                     FVASVFLQVEIGVAFLVLLLFTGLSLLQLHVQMQKENKMSMLVLKGG"
     gene            32403..33035
                     /locus_tag="VQ862_000327"
     CDS             32403..33035
                     /locus_tag="VQ862_000327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3114731.1"
                     /translation="MIELKQVSKSFGERELFSNLSMTFEAGKVYALIGSSGSGKTTLM
                     NMIGKLEPYDGTIFYRGKDLANYKSSDFFRHELGYLFQNFGLIENQSIEENLKLGLIG
                     QKLSRSEQRLRQKQALEQVGLTYLDLDKRIFELSGGESQRVALAKVILKNPPFILADE
                     PTASIDPATSQLIMEILLSLRDDNRLIIIATHNPAIWEMADEVFTMDRLK"
     gene            33176..33454
                     /locus_tag="VQ862_000328"
     CDS             33176..33454
                     /locus_tag="VQ862_000328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001843943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComA"
                     /protein_id="HET3114732.1"
                     /translation="MKKFDNYIVEKPCDSNSDKLQKILIIENLVDDILQFPLRINNSV
                     GEIFLLQPFQKKTIFIPCYFEEDIVKVKDDDKVEWNLLEFQKFRAFLA"
     gene            complement(33963..34376)
                     /gene="ndk"
                     /locus_tag="VQ862_000329"
     CDS             complement(33963..34376)
                     /gene="ndk"
                     /locus_tag="VQ862_000329"
                     /EC_number="2.7.4.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000438285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-diphosphate kinase"
                     /protein_id="HET3114733.1"
                     /translation="MEQTFFIIKPDGVKRGLVGEVLKRIEQRGFTIEKLEFRSQVSEE
                     LIDQHYQDLVGQSFYPPIREFMTSGPVLVGVISGPKVIETWRTMMGATRPEEALPGTI
                     RGDFAKAAGENEVIQNVVHGSDSEESAKREIALWF"
     gene            complement(34487..38164)
                     /gene="rpoC"
                     /locus_tag="VQ862_000330"
     CDS             complement(34487..38164)
                     /gene="rpoC"
                     /locus_tag="VQ862_000330"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000228741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta'"
                     /protein_id="HET3114734.1"
                     /translation="MVDVNRFKSMQITLASPSKVRSWSYGEVKKPETINYRTLKPERE
                     GLFDEVIFGPTKDWECACGKYKRIRYRGIVCDRCGVEVTRTKVRRERMGHIELKAPVS
                     HIWYFKGIPSRMGLTLDMSPRALEEVIYFAAYVVIDPKDTPLEHKSIMTEREYRERLR
                     EYGYGSFVAKMGAEAIQDLLKQVDLEKEIAELKEELKTATGQKRVKAIRRLDVLDAFY
                     KSGNKPEWMILNILPVIPPDLRPMLQLDGGRFASSDLNDLYRRVINRNNRLARLLELN
                     APGIIVQNEKRMLQEAVDALIDNGRRGRPITGPGSRPLKSLSHMLKGKQGRFRQNLLG
                     KRVDFSGRSVIAVGPTLKMYQCGVPREMAIELFKPFVMREIVARDIVQNVKAAKRLVE
                     RGDERIWDILEEVIKEHPVLLNRAPTLHRLGIQAFEPVLIDGKALRLHPLVCEAYNAD
                     FDGDQMAIHVPLSEEAQAEARILMLAAEHILNPKDGKPVVTPSQDMVLGNYYLTMEEA
                     GREGEGMVFKDRDEAVMAYRNGYVHLHSRVGIATDSLNKPWTEEQRHKVLLTTVGKIL
                     FNDIMPEGLPYLQEPNNANLTEGVPAKYFLPLGGDIKEAISNLELNPPFKKKNLGNII
                     AEIFKRFRTTETSALLDRMKNLGYHHSTLAGLTVGIADIPVVDDKTEIIEESHKRVEQ
                     ITKQFRRGMITDDERYNAVTAEWRAAREKLEKRLIANQDPKNPIVMMMDSGARGNISN
                     FSQLAGMRGLMAAPNGRIMELPILSNFREGLSVLEMFFSTHGARKGMTDTALKTADSG
                     YLTRRLVDVAQDVIIREDDCGTDRGLLIRSIAEGKEMIESLEERLNGRYTKKTVKHPE
                     TGAVIIGPNELITEDKAREIVNAGVEEVTIRSVFTCNTRHGVCRHCYGINLATGDAVE
                     VGEAVGTIAAQSIGEPGTQLTMRTFHTGGVASNTDITQGLPRVQEIFEARNPKGEAVI
                     TEVKGQVTAIEEDASTRTKKVFVKGETGEGEYVVPFTARMRVEVGGQVARGAALTEGS
                     IQPKRLLAVRDVLSVETYLLGEVQKVYRSQGVEIGDKHIEVMVRQMIRKVRVMDPGDT
                     DLLMGTLMDINDFTDANKDVLIAGGVPATGRPVLMGITKASLETNSFLSAASFQETTR
                     VLTDAAIRGKKDHLLGLKENVIIGKIIPAGTGMARYRNLEPYAVNEEEYLNPPVEEEG
                     NEETTEVVVDTAVETVEETVE"
     gene            complement(38197..41808)
                     /gene="rpoB"
                     /locus_tag="VQ862_000331"
     CDS             complement(38197..41808)
                     /gene="rpoB"
                     /locus_tag="VQ862_000331"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000907130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HET3114735.1"
                     /translation="MAGHDVQYGKHRTRRSFSRIKEVLDLPNLIEIQTDSFKAFLDHG
                     LKEVFEDVLPISNFTDTMELEFVGYEIKEPKYTLEEARIHDASYSAPIFVTFRLINKE
                     TGEIKTQEVFFGDFPIMTEMGTFIINGGERIIVSQLVRSPGVYFNDKVDKNGKVGYGS
                     TVIPNRGAWLELESDSKDITYTRIDRTRKIPFTTLVRALGFSGDDEIFDIFGDSELVR
                     NTVEKDIHKNPMDSRTDEALKEIYERLRPGEPKTAESSRSLLVARFFDPRRYDLAAVG
                     RYKINKKLNVKTRLLNQTIAEPLVDPETGEILVEAGTIMTRSVIESIESHLDGDLNKI
                     VYIPNDAAVVTEPVVLQKFKVVAPTDPDRVVTIIGNANPDDKVRTVTPADILAEMSYF
                     LNLAEGLGRVDDIDHLGNRRIRAVGELLANQVRLGLSRMERNVRERMSVQDNEVLTPQ
                     QIINIRPVTAAVKEFFGSSQLSQFMDQHNPLSELSHKRRLSALGPGGLTRDRAGYEVR
                     DVHYTHYGRMCPIETPEGPNIGLINNLSSYGHLNKYGFVQTPYRKVDRETGVVTNEIV
                     WLTADEEDEYTVAQANSRLNEDGTFAEKIVMGRHQGVNQEYPANIVDYMDVSPKQVVA
                     VATACIPFLENDDSNRALMGANMQRQAVPLINPQAPYVGTGMEYQAAHDSGAAVIAQY
                     DGKVTYADADKVEVRREDGSLDVYHIQKFRRSNSGTAYNQRTLVKVGDVVEKGDFIAD
                     GPSMENGEMALGQNPIVAYMTWEGYNFEDAVIMSERLVKDDVYTSVHLEEYESETRDT
                     KLGPEEITREIPNVGEDALKDLDEMGIIRIGAEVKEGDILVGKVTPKGEKDLSAEERL
                     LHAIFGDKSREVRDTSLRVPHGADGVVRDVKIFTRVNGDELQSGVNMLVRVYIAQKRK
                     IKVGDKMAGRHGNKGVVSRIVPVEDMPYLPDGTPVDIMLNPLGVPSRMNIGQVMELHL
                     GMAARTLGIHIATPVFDGASSEDLWSTVKEAGMDSDAKTILYDGRTGEPFDNRVSVGV
                     MYMIKLHHMVDDKLHARSVGPYSTVTQQPLGGKAQFGGQRFGEMEVWALEAYGASNVL
                     QEILTYKSDDINGRLKAYEAITKGKPIPKPGVPESFRVLVKELQSLGLDMRVLDEDDQ
                     EVELRDLDEGMDEDVIHVDDLEKAREKAAQEAKAAFEAEEAEKATKAEATEEAAEQE"
     gene            42224..42294
                     /locus_tag="VQ862_000332"
     tRNA            42224..42294
                     /locus_tag="VQ862_000332"
                     /product="tRNA-Cys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:42256..42258,aa:Cys,seq:gca)
     gene            complement(42492..43823)
                     /locus_tag="VQ862_000333"
     CDS             complement(42492..43823)
                     /locus_tag="VQ862_000333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000390004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HET3114736.1"
                     /translation="MEDPSSQNLLLQFVLLFILTVLNAFFSATEMAMVSLNRARVEQK
                     AEEGDRRYIRLLKVLENPNHFLSTIQVGITLITILSGASLTDTLGRVIASWLGNGETA
                     QAVATFLSLAFLTYISIVFGELYPKRIALNLKDALAIRTAPIIIGIGKLVSPFVWLLA
                     ASTNFLSHLTPMSFDDADEKMTRDEIAYMLTNSEETLDADEIEMLQGVFSLDELMARE
                     VMVPRTDAFMVDIQDDSQAIIQSILKQNYSRIPVYDGDKDNVIGIIHTKSLLKAGFVD
                     GFDNIVWKRILQDPLFVPETIFVDDLLKELRNTQRQMAILLDEYGGMAGLVTLEDLLE
                     EIVGEIDDETDKAAIDVHQIGEDTYIVQGTMTLNDFNNYFDVELESDDVDTIAGYYLT
                     GVGTIPTTEKLSYELVSQNKQFILTNDKVKNGRVTKVKVQITEVEIEEETE"
     gene            complement(44114..44938)
                     /gene="endA"
                     /locus_tag="VQ862_000334"
     CDS             complement(44114..44938)
                     /gene="endA"
                     /locus_tag="VQ862_000334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001036779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-entry nuclease EndA"
                     /protein_id="HET3114737.1"
                     /translation="MNKKTRQTLIGLLVLLLLSTGSYYIKQMQSAPNSPKTNLSQKKQ
                     ASEAPSQALAESVLTDAVKSQIKGSLEWNGSGAFIVNGNKTNLDAKVSSKPYADNKTK
                     TVGKETVPTVANALLSKATRQYKNRKETGNGSTSWTPPGWHQVKNLKGSYTHAVDRGH
                     LLGYALIGGLDGFDASTSNPKNIAVQTAWANQAQAEYSTGQNYYESKVRKALDQNKRV
                     RYRVTLYYASNEDLVPSASQIEAKSSDGELEFNVLVPNVQKGLQLDYRTGEVTVTQ"
     gene            complement(44977..45165)
                     /locus_tag="VQ862_000335"
     CDS             complement(44977..45165)
                     /locus_tag="VQ862_000335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004245549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HET3114738.1"
                     /translation="MNKKSSYVINRLLLVIIVLILGTLALGIGLMVGYGILGKGQDPW
                     AILSPAKWQELIHKFTGN"
     gene            complement(45158..46441)
                     /gene="murA"
                     /locus_tag="VQ862_000336"
     CDS             complement(45158..46441)
                     /gene="murA"
                     /locus_tag="VQ862_000336"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HET3114739.1"
                     /translation="MDKIVVQGGDNRLVGSVTIEGAKNAVLPLLAATILASEGKTVLQ
                     NVPILSDVFIMNQVVGGLNAKVDFDEEAHLVKVDATGDITEEAPYKYVSKMRASIVVL
                     GPILARVGHAKVSMPGGCTIGSRPIDLHLKGLEAMGVKISQTAGYIEAKAERLHGAHI
                     YMDFPSVGATQNLMMAATLADGVTVIENAAREPEIVDLAILLNEMGAKVKGAGTETIT
                     ITGVEKLHGTTHNVVQDRIEAGTFMVAAAMTGGDVLIRDAVWEHNRPLIAKLLEMGVE
                     VIEEDEGIRVRSQLENLKAVHVKTLPHPGFPTDMQAQFTALMTVAKGESTMVETVFEN
                     RFQHLEEMRRMGLHSEIIRDTARIVGGQPLQGAEVLSTDLRASAALILTGLVAQGETV
                     VGKLVHLDRGYYGFHEKLAQLGAKIQRIEASDEDE"
     gene            complement(46465..46695)
                     /locus_tag="VQ862_000337"
     CDS             complement(46465..46695)
                     /locus_tag="VQ862_000337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014017351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1146 domain-containing protein"
                     /protein_id="HET3114740.1"
                     /translation="MVQLLFTLSSHMLFIYVSFYLLKDLVRWEKVLKVTDDNTRKVRL
                     LVAFFSIVIGYILSSFFISLYHLWQEALRGLL"
     gene            complement(46753..47790)
                     /locus_tag="VQ862_000338"
     CDS             complement(46753..47790)
                     /locus_tag="VQ862_000338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PDZ domain-containing protein"
                     /protein_id="HET3114741.1"
                     /translation="MKKKIRWPLYVIAALIVTFLAFVVPLPYYIEVPGGSEDIRQVLK
                     VNDTEDKEAGAYQFVTVGVQHATLAHMIYAWLTPFTDIRSAQETTGGSSDVEFMRINQ
                     FYMQTSQNMAKYQGLKTAGKDIELKYFGVYVLNVTDNSTFKGILNISDTVTAVNDQTF
                     DSSKDLIDYVSSQKLGDSVKVTYEEDGQTKSAEGKIITLENGKNGIGIGLIDRTEVIS
                     NVPISFSTAGIGGPSAGLMFSLAIYTQIAHPDLRNGRIVAGTGTIDRDGNVGDIGGID
                     KKVVASARAGAAIFFAPDNPVSEEEQKAHLDAKNNYQTALEAAKTIKTDMKIVPVKTL
                     QDAIDYLKNNP"
     gene            complement(47774..48262)
                     /gene="coaD"
                     /locus_tag="VQ862_000339"
     CDS             complement(47774..48262)
                     /gene="coaD"
                     /locus_tag="VQ862_000339"
                     /EC_number="2.7.7.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pantetheine-phosphate adenylyltransferase"
                     /protein_id="HET3114742.1"
                     /translation="MSDKIGLFTGSFDPMTNGHLDIIERASRLFDKLYVGIFFNPHKQ
                     GFLPLENRKRGLEKALGHLENVEVVASHDELVVDVAKRLGATFLVRGLRNAADLQYEA
                     SFDYYNHQLSSDIETIYLHSRPEHLYISSSGVRELLKFGQDIACHVPESILEEIRNEK
                     KD"
     gene            complement(48252..48791)
                     /gene="rsmD"
                     /locus_tag="VQ862_000340"
     CDS             complement(48252..48791)
                     /gene="rsmD"
                     /locus_tag="VQ862_000340"
                     /EC_number="2.1.1.171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006147838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(966)-N(2))-methyltransferase
                     RsmD"
                     /protein_id="HET3114743.1"
                     /translation="MKIVSGIYGGRPLKTLEGKTTRPTSDKVRGAIFNMIGPYFEGGR
                     VLDLYAGSGGLSIEAVSRGMSSAVLVERDRKAQTIVAENIQMTKEVGKFQLLKMDAER
                     ALEQVSGEFDLVFLDPPYAKEQIVADIEKMAKRELFSEDVMVVCETDKAVELPEEIAC
                     LGIWKEKIYGISKVTVYVR"
     gene            complement(48856..49848)
                     /locus_tag="VQ862_000341"
     CDS             complement(48856..49848)
                     /locus_tag="VQ862_000341"
                     /EC_number="6.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016502595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--ammonia ligase"
                     /protein_id="HET3114744.1"
                     /translation="MKKSFIHQQEEISFVKNTFTQYLKDKLEVVEVQGPILSKVGDGM
                     QDNLSGVENPVSVKVLQIPDATYEVVHSLAKWKRHTLARFGFGEGEGLFVHMKALRPD
                     EDSLDATHSVYVDQWDWEKVIPNGKRNIVYLKETVEKIYKAIRLTELAVEARYDIESI
                     LPKQITFIHTEELVERYPDLTPKERENAICKEFGAVFLIGIGGELPDGKPHDGRAPDY
                     DDWTSESENGYKGLNGDILVWNESLGGAFELSSMGIRVDEETLRRQVEITGDEDRLEL
                     EWHKSLLNGLFPLTIGGGIGQSRMAMFLLRKRHIGEVQTSVWPQEVRDTYENIL"
     gene            complement(49959..50642)
                     /locus_tag="VQ862_000342"
     CDS             complement(49959..50642)
                     /locus_tag="VQ862_000342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015545711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Bax inhibitor-1/YccA family protein"
                     /protein_id="HET3114745.1"
                     /translation="MNHTIIHDRAGLNQFYAKVYAFVGLGIGLSALVSGLMLTVFQSQ
                     LVYLLMQGRLWLTIATFAELALVFVASSMASRNSPAALPVFLLYSVLNGFTLSFVVAF
                     YTPGTVLSAFVSSALLFFVMAAVGIFTKKDLSGIGRAMMAALIGLLIAMVVNIFLASG
                     FFDYMISVAMVLVFSGLIAWDNQKIRLAYEQSQGRVATGWVVSMALSIYLDFINLFLS
                     ILRIFGRND"
     gene            complement(50698..51438)
                     /locus_tag="VQ862_000343"
     CDS             complement(50698..51438)
                     /locus_tag="VQ862_000343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000152696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA methyltransferase"
                     /protein_id="HET3114746.1"
                     /translation="MTIITSKANSVVKNAKKLRQKKYRKSAYLIEGWHLFEEAVQAGV
                     TIEKIFALENYRDQLATFSQTVWVSEDILLDLADSQTPQGIVAVVQKEEVGQADLSQG
                     KFLFLEDVQDPGNVGTIIRTADAAGFTGVIVSDKSADIYSLKTLRSMQGSHFHLPIYR
                     MTSPALLDETKKVAIPVLATTLSKDSVDYRELPSIENFVLVMGNEGQGISPLMAESAD
                     QLVHISMKGQAESLNVAVAAGILIFHLS"
     gene            51472..51750
                     /locus_tag="VQ862_000344"
     CDS             51472..51750
                     /locus_tag="VQ862_000344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001174612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acylphosphatase"
                     /protein_id="HET3114747.1"
                     /translation="MQKVRMIAQGRVQGVGFRWGVYSLALEIGGITGRVWNNDDGTVE
                     ILAQADSSAIMAKFIQEIRKGPTPFSKVSYLDVKLSNFPPYSDFKIAN"
     gene            51828..52754
                     /gene="yidC"
                     /locus_tag="VQ862_000345"
     CDS             51828..52754
                     /gene="yidC"
                     /locus_tag="VQ862_000345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HET3114748.1"
                     /translation="MKSIKRFAFSAMGVAMLLVLTGCVNVDKTTGQPTGFIWNTIGAP
                     MAEAIKYFATDKGLGFGVAIIIVTIIVRLIILPLGIYQSWKATLHSEKMNALKHVLEP
                     HQTRLKEATTQEEKLEAQQALFAAQKEHGISMFGGVGCFPILLQMPFFSAIYFAAQHT
                     EGVAQASYLGIPLGSPSMILVACAGVLYYLQSLLSLHGVEDEMQREQIKKMIYMSPLM
                     IVVFSLFSPASVTLYWVVGGFMMILQQFIVNYIVRPKLRKKVREELAKNPPKASAFSK
                     PSGRKDVTPEQPTAITSKKKHKNRNAGKQRSR"
     gene            complement(52829..53623)
                     /gene="pflA"
                     /locus_tag="VQ862_000346"
     CDS             complement(52829..53623)
                     /gene="pflA"
                     /locus_tag="VQ862_000346"
                     /EC_number="1.97.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001288284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate formate lyase-activating protein"
                     /protein_id="HET3114749.1"
                     /translation="MSEETIDYGQVTGMVHSTESFGSVDGPGIRFIVFLQGCHMRCQY
                     CHNPDTWAMESNKSRERTVDDVLTEALRYRGFWGNKGGITVSGGEALLQIDFLIALFT
                     KAKEQGIHCTLDTCALPFRNKPRYLEKFDKLMAVTDLVLLDIKEINEEQHKIVTSQTN
                     KNILACAQYLSDIGKPVWIRHVLVPGLTDRDDDLIELGKFVKTLKNVDKFEILPYHTM
                     GEFKWRELGIPYSLEGVKPPTADRVKNAKKLMDTESYQDYMKRVHG"
     gene            complement(53749..54999)
                     /locus_tag="VQ862_000347"
     CDS             complement(53749..54999)
                     /locus_tag="VQ862_000347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000856498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate decarboxylase"
                     /protein_id="HET3114750.1"
                     /translation="MKTPFINREELEAIVAEFPTPFHLYDEKGIREKARAVNQAFSWN
                     KGFKEYFAVKATPTPAILKILQEEGCGVDCSSYVELLMSHKLDFLGSEIMFSSNNTPD
                     KEYAYARELGATINLDAFEDIEHLERVAGIPEIISCRYNPGGVFELGTDIMDNPGEAK
                     FGMTKDQLFEAFAILKEKGAKTFGIHSFLASNTVTHLYYPELARQLFELAVEIKEKLG
                     ISLDFINLSGGIGVNYRPDQEPNDIALIGEGVRKVYEEVLTSAGLGQVKIFTELGRFM
                     LAPHGALVTRVTHKKETYRTYLGVDASAVNLMRPAMYGAYHHISNVTHPDGPAEAVDV
                     VGSLCENNDKFAVNRELPHTEIGDLLVIHDTGAHGFSMGYQYNAKLRSAEILYTEEGK
                     ARQIRRAERPEDYFATLYGFDFEE"
     gene            complement(55066..55893)
                     /gene="purR"
                     /locus_tag="VQ862_000348"
     CDS             complement(55066..55893)
                     /gene="purR"
                     /locus_tag="VQ862_000348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004242125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pur operon repressor"
                     /protein_id="HET3114751.1"
                     /translation="MKLRRSDRMVVISNYLINNPYKLTSLNTFAEKYESAKSSISEDI
                     VIIKRAFEEIEIGHIQTVTGAGGGVIFTPSISSQDAKEMVEDLRTKLSESDRILPGGY
                     IYLSDLLSTPAILKNIGRIIAKSFMDQKIDAVMTVATKGVPLANAVANVLNVSFVIVR
                     RDLKITEGSTVSVNYVSGSSGDRIEKMFLSKRSLKAGSRVLIVDDFLKGGGTVNGMIS
                     LLREFDSELAGVAVFADNAQEEREKQFDYKSLLKVTNIDVKNQAIDVEVGNIFDEDK"
     gene            complement(56160..57101)
                     /locus_tag="VQ862_000349"
     CDS             complement(56160..57101)
                     /locus_tag="VQ862_000349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exoribonuclease YhaM family protein"
                     /protein_id="HET3114752.1"
                     /translation="MKISHMKKDELFEGFYLIKSADLRQTRAGKNYLAFTFQDDSGEI
                     DGKLWDAQPHNIEAFTAGKVVHMKGRREVYNNTPQVNQITLRLPQAGEPNDPADFKVK
                     SPVDVKEIRDYMSQMIFKIENPVWQRIVRNLYTKYDKEFYSYPAAKTNHHAFETGLAY
                     HTATMVRLADAISEVYPQLNKSLLYAGIMLHDLAKVIELTGPDQTEYTVRGNLLGHIA
                     LIDSEITKTVMELGIDDTKEEVVLLRHVILSHHGLLEYGSPVRPRIMEAEIIHMIDNL
                     DASMMMMSTALALVDKGEMTNKIFAMDNRSFYKPDLD"
     gene            complement(57091..58347)
                     /locus_tag="VQ862_000350"
     CDS             complement(57091..58347)
                     /locus_tag="VQ862_000350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000444769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA recombination protein RmuC"
                     /protein_id="HET3114753.1"
                     /translation="MESLLILLLIANLAGLFLIWQRQDRQEKHLSKSLEDQADHLSDQ
                     LDYRFDQARQASQLDQKDLEVVVSDRLQEVRIELHQGLTQVRQEMTDNLLQTRDKTDQ
                     RLQALQESNEQRLEQMRQTVEEKLEKTLQTRLQASFETVSKQLESVNRGLGEMQTVAR
                     DVGALNKVLSGTKTRGILGELQLGQIIEDIMTPAQYEREYATVENSSERVEYAIKLPG
                     QGDQEYVYLPIDSKFPLADYYRLEEAYETGDKDEIERCRKSLLASVKRFARDIRNKYI
                     APPRTTNFGILFVPTEGLYSEIVRNPVFFDDLRREEQIIVAGPSTLSALLNSLSVGFK
                     TLNIQKSADHISKTLASVKTEFGKFGGILVKAQKHLQHASGNIDELLNRRTIAIERTL
                     RHIELSEGEPALDLLHFQENEEEYED"
     gene            complement(58349..59011)
                     /locus_tag="VQ862_000351"
     CDS             complement(58349..59011)
                     /locus_tag="VQ862_000351"
                     /EC_number="2.7.6.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000006147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine diphosphokinase"
                     /protein_id="HET3114754.1"
                     /translation="MSEYKLSENNWTRVAVFAGGDRGHYRTDFDGFVGVDRGSLWILE
                     EDLPLALAVGDFDSVTEEERQVIQKRAQYFVQARPEKDDTDLELALLTIFKQNPQAQV
                     TIFGALGGRIDHMLANVFLPSNPKLAPYMHQIEIEDGQNLITYCPEGISQLEPRSDYD
                     YLAFMPVRDSQLTILGAKYELTEENFFFKKVYASNEYIDREVSVTCPDGYVVVLHSKD
                     RR"
     gene            complement(58974..59630)
                     /locus_tag="VQ862_000352"
     CDS             complement(58974..59630)
                     /locus_tag="VQ862_000352"
                     /EC_number="5.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HET3114755.1"
                     /translation="MSQYKIAPSILAADYANFEREIKRLEATGAEYAHIDIMDGHFVP
                     QISFGAGVVEALRPHSKMVFDCHLMVSNPEHHLEDFVRAGADIISIHVEATPHIHGAL
                     QKIRSLGVKPSVVINPGTPVEAIKHVLHLVDQVLVMTVNPGFGGQAFLPETMDKVREL
                     VALRDEKGLNFEIEVDGGIDDQTIAQSKEAGATVFVAGSYVFKGDVNERVQTLRKQLD
                     "
     gene            complement(59641..60519)
                     /gene="rsgA"
                     /locus_tag="VQ862_000353"
     CDS             complement(59641..60519)
                     /gene="rsgA"
                     /locus_tag="VQ862_000353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome small subunit-dependent GTPase A"
                     /protein_id="HET3114756.1"
                     /translation="MQGQIIKALAGFYYVESDGQVYQTRARGNFRKKGHTPYVGDWVD
                     FSAEENSEGYILKIHERKNSLVRPPIVNIDQAVVIMSVKEPDFNSNLLDRFLVLLEHK
                     GIHPIVYISKMDLLEDGGELDFYQQTYGDIGYDFVTSKEELLPLLTGKVTVFMGQTGV
                     GKSTLLNKIAPDLNLETGEISDSLGRGRHTTRAVSFYNLNGGKIADTPGFSSLDYEVS
                     TAEDLNQAFPEIATVSRDCKFRTCTHTHEPSCAVKPAVEEGTIAPFRFDNYLQFLSEI
                     ENRRETYKKVSKKIPK"
     gene            complement(61112..61885)
                     /locus_tag="VQ862_000354"
     CDS             complement(61112..61885)
                     /locus_tag="VQ862_000354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell surface protein"
                     /protein_id="HET3114757.1"
                     /translation="MRKKLVNSLMCAVVLSGFPIATYANEKNIGPNITVSNGQTRLSI
                     PEKNGVEVIQSEENRVVYEVKEAAKIETSDGDMVAPIVVDSRITSINNQVVQGKTVYT
                     ADLEKATFVEEGYNKLAKPTNILDHIFGIQKVHAYTQNITTHQSQFDSTYSVELYTVV
                     HWVSYDGGVQKNITKISGGVDFHERDIEIESSSVEVRQGGWYSSQQKWFHPGARSSWE
                     YSTGFSKVGPGENRVVTNYTVNLIRYGDRWSAYLQNNPW"
     gene            complement(62575..63447)
                     /gene="rsmA"
                     /locus_tag="VQ862_000355"
     CDS             complement(62575..63447)
                     /gene="rsmA"
                     /locus_tag="VQ862_000355"
                     /EC_number="2.1.1.182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (adenine(1518)-N(6)/adenine(1519)-N(6))-
                     dimethyltransferase RsmA"
                     /protein_id="HET3114758.1"
                     /translation="MRIADYSVTKAVLERHGFTFKKSFGQNFLTDTNILQKIVDTAEI
                     DDQVNVIEIGPGIGALTEFLAERAAEVMAFEIDHRLVPILADTLRDFDNVTVVNEDIL
                     KVDLAQHIQNFKNPDLPIKVVANLPYYITTPILMHLIESGIPFSEFVVMMQKEVADRI
                     SAQPNTKAYGSLSIAVQYYMTAKVAFIVPRTVFVPAPNVDSAILKMVRRPVPAVAVED
                     ENFFFKVSKASFTHRRKTLWNNLTGYFGKTEEVKDKLTKALDQAGLSPSVRGEALSLE
                     EFASLADALKGQGL"
BASE COUNT        18634 a        14235 c        11692 g        19042 t
ORIGIN      
        1 tactataaat ttgatatgag aatagtcttt ctcaacatcc ttacccaaca agaatgctgt
       61 agcgtccttc ttaacttgaa ccaggtcaat attctgggct tgggctgcat agacgcagcc
      121 acaataacat tgacgataga tatcatactc ctcacacatc tctactgaac gtttgtagcc
      181 ttgatttttc ttgaaatcgt tgggaagata gtgggtcgtg taaatttttt gcacatcgat
      241 tccgatgctg ttgatggttt gagaattctt atgaggactg atggtcaagg ctgaaccaaa
      301 gtagtcaaag cccaagtcca tagccacttg cgctgtttta tccagtcggt agtcaaaaca
      361 aaccttgcaa cggtcgccac cttcgggctc ctcctctagt cccctaacta gttttcggta
      421 ttaattgggt tcgtagggag cttctaggta ctgaaccgta tttcctgtcc gctcattaaa
      481 atcactaaca aatttcttgg tgacatagac ccgcttatgg tattctacct tgggatggat
      541 attagaattg gcaaaataga tggtcacatc tgcatacttg gtcaaatatt ctagtgtata
      601 ggtactacaa ggggcacagc aaacatgcac gagaatggtt ggccgttgct catttttcta
      661 ccatacttct accattttct gcatgacacg gtcataatta atcttctgat tggggggcat
      721 cttgcacaga attttttcta catcgatcat gttcttctcc tttttctagt cttattttat
      781 catataagtt aggagagctc aaatcaattt agaagtgaat attataaaaa gaagggttag
      841 tcattccctc cttttgtgtt ttttataagt tgttttctat agaatgctta catcatcccg
      901 cccatcatgc ttggatccat tgctggagct ggggctactg gttctggttt attggctacg
      961 actgcttctg ttgtcaaaat caagctggct acagatgctg cattttgtag ggctgaacga
     1021 ctcactttaa ctggatcaat gataccttga tcaatcatgt taacccactc gccagttgct
     1081 gcgttgaatc ctataccaag ctcagcattt ttcaaacgat cgataacgat agatccttca
     1141 aatcctgcat tgtgagcaat ttgacgaaca ggttcttcca aagcacggag aacaatatta
     1201 cgtcctgtta cttcatctcc tgtcaattcc aaggtagcaa cagctggaat cacattggca
     1261 agagctgttc caccacctgc aacaatacct tcttcaacag ctgcacgagt agcgttgagg
     1321 gcatcttcaa tgcggagttt catttctttc aactcagttt cagttgcggc tccgacctta
     1381 ataaccgcta caccacctga caatttggcc aagcgttctt gcaatttttc acggtcaaat
     1441 tcagaagttg tagtttcgat ttgagacttg ataaccgcaa cacggtgaga aatcgcttca
     1501 ggatttcctg caccttctac aataaccgtg ctatctttgt ccacggtcac tctcgctgct
     1561 tgaccaagag cttcaattgt cgcatctttc aactcaagac caaggtcttc tgtgataact
     1621 gttccgcctg ttaagatggc gatatcttca agcatggctt tgcgacggtc accaaaacca
     1681 ggtgccttga ctgctactac gttgaaggtt ccacgaatct tgttcaaaac aagagttgga
     1741 agagcctcac catccacatc atccgcaata atcaagagtg gacgattgct ttggagaatg
     1801 ctttccaaaa gtggcaagat ttcttggata ttggaaattt tcttgtctgt aatcaaaatg
     1861 tacggatttt caaggtcagc caccattttt tcgctatctg tcaccatgta ctgtgaaagg
     1921 taaccacggt caaactgcat tccttctacg acttcaagct ctgtttccat accacgtgac
     1981 tcttcgatgg tgatgacacc gtctttgcca actttttcca ttgcttcaga gatgtactca
     2041 ccaacttttt cagaacgaga agatacggct gcaacttgag cgatagcttc tttattggca
     2101 acagggatgg cgttgttttt caaagcttca actgctgcgg caactgctgt ttcaatccca
     2161 cgacgaatac cgattggatt tgcacctgct gtgacgtttt tgattccttc acggacgata
     2221 gcttgggtca agactgttgc agtcgtagtt ccgtcacctg cgatatcatt ggttttagaa
     2281 gctacttctg atactaactt agcacccata ttttcaaaat ggtcttccaa ttcgatttct
     2341 ttggcaatag tcacaccgtc attggtaatc aatggtgagc caaatgattt ttcaagaacg
     2401 acattgcgac cttttggtcc caaggttact ttaacagtgt ctgcaaggat atcgacacca
     2461 cggaccatag ctgaacgggc atctgatgaa aatttaattt cttttgacat acttactttc
     2521 tccttctatt cttcaatgat tgccaagatg ttagcttcgc ctacgatgat gtacttttca
     2581 tcgccatctt tgacatcaag acctgcgtgg gcttcaacta agacacggtc tccagtttta
     2641 acacttggag caaccaagtc accgttcaag gtacgaacac cttgtccagt agccacaact
     2701 tgggctgttt tggttttttc ttgggctgaa cctgcgagaa caaagccccc aacggtttgt
     2761 tctttttctt ctatttttaa gaccacacgg tcccctaatg gtttcaacat ctgatttcct
     2821 ccataatgag atagatatta ttagcactct ttatacctga gtgctaattc atagttctat
     2881 tgtatcactt agtcagaaat aatcaagaaa aaagtctgac tttctcaaga taaaaagcct
     2941 gagaccaact cagacttttt aatgtttata ctcaatgaaa atcaaagagc aaactaggaa
     3001 gctagccgca gactgctcaa agcattgctt tgatgttgtg gataaagcta acgtggtttg
     3061 aagagatttt cgaagagtat taaaatggca attcttcctc ttccaagact aaatctgcca
     3121 aatcttggcc tgcattattt tcacgcatgg cacgttgagc acgactttcc aagagttgga
     3181 atcctgttac aagtacttcg gtcacgtagt tcatttggcc atttttctca aagcgacggg
     3241 tacgcaattc tccatcaacg gaaatgagac tacctttggt tgcgtagctt gccaaagttt
     3301 ctgctagtct gccccatagg accatattga caaaatcagc ttcacgttca ccgttttggt
     3361 ctttgtaacg acggttcaca gcgatagttg ctcgcgctac cgacttgtca ttgttggttt
     3421 tgtgcaattc tggtgtagac gttaaacgcc caatcatgat aactttatta tacatatttt
     3481 cttcctccta cttatctatt cgtaggaaat caaaaaaagt tacagaaatt tgtaactttt
     3541 cgaggaaatt tcttattttt tatgaatcat gaaacctgtc gcctgttgat tggccataat
     3601 ggtcatatct gtaatctgaa cacggcgagg ctgactggtc acatagacta ctgtgtctgc
     3661 aatatcctga gcttgcaagg cttctattcc ttggtaaacg gacgcagctc gctctttatc
     3721 accatgaaaa cgaacagttg agaaatctgt ttcgacaatc ccaggctgaa tggttgtcac
     3781 cttgatatcc gttgcgatgg tatcaattcg cagtccatcc gaaaaggtct taaccgcagc
     3841 cttggtagct gagtaaacag cggcaccagc ataggcgtag attcctgcgg ttgaccccat
     3901 attgataata tgaccttgat tgacttttat cattgctggc aagaaacagc gagtaaccgc
     3961 catcagacct ttaacattgg tatccaacat ggtcaacata tccaactcct catagtcttg
     4021 atagggagcc aagtcaagag ccagtccggc gttgttgacc aagatatcaa tcctccctat
     4081 cgtttctaga atatcagagc aaacagtctt caccatgacc atatccgtca catctagtgg
     4141 aaaagtccag acggtttgat ttggaaagct tactgcaaac tccgacttga ggatttctaa
     4201 tctgtctatc cgtcgtcctg ttagaacgac atcctcaccc tgctccagat aagcacgcgc
     4261 aatcgcttca ccgattcctg aggttgctcc cgtaatcact acattttttg ccatcttatt
     4321 tccttctatc agatgctgac aagttcctag gcagtccagt gtttcgctgg gtcgaacggt
     4381 gttccgacaa cttggtcttc tgataattca agcaccccac gtttttgcgg agcatttggc
     4441 aaatgcaatt cacgaggact acacatcatc ccaaaactct tttcaccacg aagttcgcct
     4501 gggaaaatga aattcccttt tggcatcatg gcaccaggaa gagccacaat ggttttcaac
     4561 ccaacacgcg cattaggtgc tcctgcaacg atttgcacta tcttgtcact tgcgactgca
     4621 acttggcaga tgttgaggtg gtcactgtct ggatgagcta ccatctcgac aatttcacca
     4681 acaacaaact taggttcctt atcattaaca atttcttctg taaaaccttc cgcctgtaat
     4741 tcttggttca aacgagcgac ttgctcatct gataaaaaga cttgaccgcg ctctgcaatt
     4801 tcaaacaagc tcgaaacctc aaaaatgttc caagctactg tttccccatt ttctttgagg
     4861 aaaacacggg ctaccttgcc tttgcgttcc acattcagtt tggcatctcc gctatttttc
     4921 acgatgacca taaggacatc actgacatgt tctttgttat acgtaaaaat cattgtttcc
     4981 tttttctcct atttcaatcc tgctaaaaaa tcgttaattt gctccttact tttacggtcg
     5041 cgattgacaa aacgaccgat ttccttgtcc ttttctagaa caacaaggct aggaattccg
     5101 taaacatccc agagtttggc caaatccata tactgatctc ggtccattcg aataaaggtg
     5161 aactctggat tggtctcttc aatctctggt aaggcaggat aaatataacg acaatcgcca
     5221 caccagtctg ccacaaaaag gaagaccttc ttgcccgctt tttccactaa agatgctaat
     5281 tcttctaaac ttgctggctg tatcataaga cttcctcctc atagactagg tcttcatttt
     5341 catagacaaa ggtataatga cggccatcct caaaaatgac gccaccaacc aagctctcca
     5401 gactgctttc gtaaacttga acataaaggg tcgcaatttc ccccatgtcg gaaaaatggt
     5461 ctcgcacaat ctctgtcaac tcttcctgag tcttcatgag cttacggtca tctgcaactt
     5521 ttttcgtagc aagagcaagg cttccgatac ctagcagagc caagcctgcc atccacattt
     5581 ttttagcttt cataccattc attttaacac aaaaaaggct tcaggacaaa tgaggaagca
     5641 gcagaaaagc aagtaaaaag cctcttcctt taaggaaaag gacttcttat actaagagca
     5701 aactagaaag ctagccgcag gctgctcaaa acacggtttt gaggttgtag ataaggcgac
     5761 gttgacgtgg tttgaagaga ttttcaaaga gtattattct tattgccagg cacctaagtt
     5821 gccaacgtag taaccatcag gtgtgtaggt attgcgaagc atcttacctg atgaagccag
     5881 ataatactac ttgccattgt ctttgaccca atcattcgca atcatggaac cagaagaact
     5941 tacataatac cattctccct tgtcataaac ccaagtactg actttcatgg ttcctgagca
     6001 attaaaggca aaaaaactgt ccaatatcat tcgtttttta aaagcattcg acactacatc
     6061 atctacgctg tagtacatag atacatcaaa cgtaaaagcc aaaatatcga aaaatataca
     6121 acttttaaag gcagcatttc attttttaaa gtctaacaac catagaactg aaatcagagc
     6181 aaggcatcaa tttcctactc ttagtacgcc tattttgatg gttgaagtga agattttttt
     6241 atttagcgta gacaatttcc aacttcccaa aagccacatc tccacggata atcaaggttt
     6301 tgctggttgg ggctacagga gcgtccgcct tggctgcacc aaaggatgtt tctactttca
     6361 aatcgacacg ccagtgttgc ggaacataga cagttgcatt accaaaagct acttcaatat
     6421 ttaaagttgc aaaatcacct aacatctctg cattgtcata gtagattttt gcattgccaa
     6481 aaccaacttc tacttggtct tctaccaatt cttggtcttg cttgtagaaa gtccctgtcc
     6541 caaaagcaac ttccttatct ataagaatgt ttttttcacc atcataccac cattttttcc
     6601 cattccaagt tctgttagaa tgagtcaaca tatttactcc gagaacgatt agaactcctg
     6661 cccagattag tgtctggttt ggaatcggta aaatgccata aaagtggtta gcaatcatta
     6721 aggctactag agctgtaaaa gaggctgaag ttaagtggcg acgcaacaaa gctccaactg
     6781 attggtaggc aaaaaaagca ataccaatca agggccaaat gtgccctcct agagaaggga
     6841 ttccaaaatt tccttgtact aatattaaag ctgctagtac aagcaacaca ataccaaatg
     6901 ctttcttttt catgttctta cctcatattt cttagatttt cttttaggag ggattggtaa
     6961 tgccgtgaca catgaacctc cttgtgggtt tgataaaagg aaatggtgcc cgttcctgaa
     7021 aaggacttgt ccaccgaata gatttgccga atattaacga tcgttgactt ggatactcga
     7081 ctaaaatagc gaggaaggat agcctctaac tcatagagtt tgagccgaac ttcgtaggca
     7141 tttttctggg tatgggcata aatcttgcta ccttctgtct caaagaagag aatttccgac
     7201 aagtccagat aatattcacc cgtccccttg taaaaaatca acctaggaga cttggattct
     7261 tgcaagagcc gttgcaagtc tgcaatttca tctgtcaaag tgggggtctt gatgacaatt
     7321 tcagtctcct ctaaattgcc gtcaatctca attcgtaact tcatcacatc tcctttctga
     7381 ctctactata tcaaagctaa gttaggaata caagggcaaa aaagcaagtg gtcaatttga
     7441 agcagtaagt ggttgtagga ctagcttaac ttacatgtca gaataagaag aaaaggaatc
     7501 cccacaccag accacaagca tagccaacca agacatcctt gggataatga acacccccta
     7561 aaaccctcac caaccccagc aaagctgaaa agatcaagca tactaagcca ataggtagac
     7621 tagcatgcag acaggccatg gagatgatag ttgcagaaaa gacatggcga ctgggcatcg
     7681 accgtcccga actatcctta tcaagaaggg gacagatatc ccaagtttca taaggtctcg
     7741 ggtgattgat ttttttacga aacagggaca aggccacaaa acctgatgca ggaataagca
     7801 cataaactcc aacttgctga ccaagtccta gttgcaggta agtggtgact agcaagatca
     7861 gatagaccag gggcatggcg actgtcatca aacgattgaa actgcgtaat aggaataaaa
     7921 gaattggacg actagttagt ctggatctga tatttcgata ccattcttga taatttttca
     7981 tttatgcttc tcatactttt ctagaacttg ttgagatgtt ttccccttgg caagccaatc
     8041 cactagcttg tccaagcgac gtatttcctg catcagagga tcatcaattt cctcaatacg
     8101 gacaccgcaa atcttccctg taattgcaat tcgttcaggg acataatatg gtgcttgtcg
     8161 aaaaaaatct ccgtaagtaa catccctatc cagacaagta agaacgtcac tcacttcata
     8221 ccctgtcaac caactggtca cttggtgaac tgactctgcc tttccaccct ttcgctcaac
     8281 ttttgcaatc aaggctaagt agacagcagc aaatttcata ttgtataatt tctgactcat
     8341 acttctctct ttctatgtgt actagtataa ataagaaaaa gaaggccgtc aagccttctt
     8401 ttgatttatt cttctgcttc atcttctgta aattgactat tgtacaagtc agcgtagaag
     8461 ccaccttaca ccatcagttc ctcatagttg ccttgctcga tgatatttcc atctttcatg
     8521 accaagatca agtctgcatt tcggatggtt gacaagcggt gggcaatgac aaaggatgtg
     8581 cgtccttcca tcaaacggtc catggctttt tggatcaatt cctctgtccg tgtgtcaaca
     8641 gaagaagtcg cctcatccaa aatcaaaagc ggtgcatcct taagaagggc acgagcaata
     8701 gtcaatagtt gtttttgtcc tacagacaag gtcacggtgt catccaagat ggtatcatag
     8761 ccatctggca aggtcataat aaagtggtga attcccacag ccttactagc ttccatcatt
     8821 cgttcatcac taatccctat ttgattatag atgagattgt ctcgaatagt tccttcaaag
     8881 agccaggtat cctgcaagac cattgaaaag gcatcatgca cttctgaacg cgtcatagcc
     8941 ttggtatcca caccatcaat gcgaatactt cccttatcaa tctcatagaa tttcatcaaa
     9001 agattgacaa tggttgtctt accagcccca gtcggcccaa caatggcaac cctttgacca
     9061 gcatgagctg tcgcagagaa gtcatagtct tgaacattga caccgtccac cagaatttct
     9121 cctgctgaca cgtcgtagaa acgtggaatc agattgacca gagttgattt accagaacct
     9181 attgacccaa taaaggccac tgtttgacca gtttctgctt taaagctaac atgttcaata
     9241 actgcctccg aatttgccgc atagcggaag gtcacatcct taaactcgac ctgacctttg
     9301 aagttttcat cagtcagctg cacttgagca gggttttgga tagaagaatg caaatctaaa
     9361 acttgattaa tccgcttagc agagaccata gttcggggaa gaacgatgaa gagtgctccc
     9421 atgagaagga agtccatgac aacctacatg gcataagaca tgaaaacaat catgtcacta
     9481 aagaaaggca gacgcgctat cggagcagcg tcgttaatca cataggcccc aatccagtaa
     9541 atcgccacac tcaaaccact tgaaatcccc atcatgatag gattcaaaat agccataaga
     9601 cggttgacaa acaaatttta acgggtcaat tcatcattta ctgctgcaaa tttttcattt
     9661 tgataatcct ctgcattgta ggcacgaacg acacgaatac ctgttaaact ctcacgagtg
     9721 atactgttca gtttatctgt cagcccctga atcaaggact gttttggaaa ggctagcgtc
     9781 atcaaaacgg tcgtcatcag gacgttgaca atcactgcca caagtacggc ccagagccag
     9841 tattctgaat gacctaaaat cttcccaata gcccagatag ccataattgg accacacgtt
     9901 accacttgca agtccatagt aatcaacatt tgaacttgag taatgtcatt ggtagtacgc
     9961 atcaagaggc taggaattga aaatttctta atctctgtct gcgagtaatc caaaactcgg
    10021 ttaaaaatat cacttctcag cctactagta taagaagccg ccactcggga tgcaaaaaat
    10081 ccaactgcaa ctacggacaa gaaggcaaga aagggcattc ccatcatcat gcttgccggc
    10141 tgccacaact catctaaatt agttccttga ctacctagca aatccgtaat tttcgagata
    10201 taggtcggca cttccaactc tagatagacc gaaaagcaag taaagagaat ggctagtaaa
    10261 atcatccccc attcttttct actaattctt ttggctaatt tctttattct ctcctcctat
    10321 tcccttgata tttgcctgta gttgaccgag aactttctca aaaatcagta attcatcttc
    10381 atcaatgtct tccatcaact gcttgtctat gcgttcaaaa aagccttaac ctgttgcatc
    10441 tgagaacgtg ctttgtccgt cagacgaaca aacttagccc gcttatcaac aggactcgcc
    10501 tccaattcca ccaaaccatt ttgcactata cgcttaacca gattactagc aacagacttg
    10561 gtaatattga gttcctgctc gatatcttta atcaagacca agtcttggtt tttctcgcga
    10621 ttatccaaaa aacgcacaac ctgaccttgc ggcccaccca taaattcaat gccgcaacgt
    10681 ttggattcct tttgcaccat caggtaaatt tgatgaccaa aacgcttaaa gactaacatc
    10741 ggtttatcca taatctcccc cttctaaata aaaatagttc tctggagaat aattaaattt
    10801 ctatgagaac tattttcttg attaaaaaaa tcccaagtga ttttctcact taggatcatg
    10861 ttctataggt taaattaaaa cccatctacg ttcgtataaa tcttttggac gtcttcgtcg
    10921 tcttcaagaa cgctgtaaag tttttcaaag gtttcaaggt cttcgcctga caattccact
    10981 tctgactgag gaatcatttc caattcagtc acttggaatt cttcaatacc agactcacgg
    11041 agagcaacga tagccttgtg aaggtcagtt ggcgctgtgt aaactgtgat tgtaccttct
    11101 tgtgcttcta cgtcatccac atccacatcc gcttcgagca attgctcaaa gactgcgtcc
    11161 gcatcttcac ctccaaatac aataacacct ttgttgtcaa aaaggtaaga aacagaacct
    11221 gaagcgccca tgtttccgcc gtttttacca aaggctgcac ggacattggc tgctgtacgg
    11281 ttaacgttag aagtcaaagt atccacaatt agcatagagc catttggccc aaaaccttcg
    11341 taacgtcctt ctgtaaaggt ttcgtctgtg tttcctttgg ctttatcaat cgctttatcg
    11401 ataatgtgtt ttggcacttg ggcttgttta gcacggtcga taacgaattt caaagctgag
    11461 tttgattctg gatctggatc acctttttta gctgctacat agatttctac accaaatttt
    11521 gcatatactt tagagttagc tccatcttta gccgttttct tggctacgat attggcccat
    11581 ttacgtccca ttaggaatct ccttttttca cattttaatc tttcttatta taacacaagt
    11641 ttttttgatt ttcactagag gaaatggatt ttattagcaa atcaagctag gatagcactt
    11701 tacctgctaa gatggtctta cctttctatc tttatcaaca gacactcatc cacattcaaa
    11761 aaacaaacta gaccattatc tgcaaataga aagtttcagc caagtttgac aaagtcagct
    11821 caaattactg tttgaagttt gtagatataa gcgacaaaaa caatcatact gcaccttttg
    11881 ttgacagtct actccagaca tatcatagtt caagtaaata ctttgaaatc caacagttct
    11941 tataggcgct attgtattct aagaaatcaa tagaagagtt tctaagcaaa cctctaatac
    12001 tcaataaaaa tcaaaaagca aactagaaag ctagccgcag gttgctcaaa acactgtttt
    12061 gaggttgcgg atagggctga cctggtttga agagattttc gaaaagtata atttacgtgt
    12121 tcccaagatg gagaaattag actagtacac tggcacttct aaaccattgc tagcaattga
    12181 tttgttcata tttaatttca ttttttccat aaatgggtat tagatataaa cagcaaaata
    12241 tttccgatac gtgtcattct tgaatttcca atcatctaaa acaagtaaag gataatcaat
    12301 cccctgtata tcaaggaatt ggctaccctt tttacttttt tacacattct gtttgataga
    12361 ttcattttaa catcacgagc atactccaat ggaaatcgct aggcaagaga taaactttca
    12421 gatatccgca gagagatcat cgcctctttt tgtcgcaagc attctcctct actagtcatt
    12481 ttctacctta tcttctacct gaggatagag agttgttccc caaatagaaa tcgtccgctt
    12541 acgcactagt ggcaaatcgg ttttttcata aaccgtacgc caccattccc aggcaagccc
    12601 ggtacactct ctaattttga cagagagatt acgaacattc ccttttaaag gaatactagt
    12661 ggtaaagtga gccgtcaaat cctgcccatt tctgtcccaa gccttaggag tcaagacttc
    12721 cttaccttga tgatcatagg ataattcatc ccaagtaata taatattggg caacataggc
    12781 accactatga tccagcagta aatctccgtt tctgtaagct gtaaccttag tctcaacata
    12841 gtctgtacta ttttgaaagg tcgcaactac attgtcacgt aaaaaagaag ttgtatagga
    12901 aatcggcaag cctggatgat ctgctgtaaa gcgactgcct tcttgaatca agtcctctac
    12961 catatccacc ttgcctgtta caactcgggc acccgaactt gggtcgcccc ctaaaataac
    13021 cgccttcact tctgtattgt ccaaaatctg cttccactct gtctgaggag ctaccttgac
    13081 tccttttatc aaagcttcaa aagcagcctc tacttcatca ctcttactcg tggtttccaa
    13141 cttgagatag acttggcgcc cataagcaac actcgaaata tagaccaaag gacgctctgc
    13201 agaaattcct ctctgtttta aatcctctac cgttacagta tcttgaaaca catctcctgg
    13261 atttttaaca gcatctacgc tgactgtata ataaatctgc ttaaaattaa caatctgaat
    13321 ctgcttttcg cctgaatgga cagagttaaa atcaatatca agagaattcc ctgtcttttc
    13381 aaagtcagaa ccaaacttga ccttgagttg ttccatgctg tgagccgtga ttttttcata
    13441 ctgcattcta gctgggacat tattgacctg accataatct tgatgccact tagccaacaa
    13501 atcgtttacc gctccgcgaa cacttgaatt gctggggtct tccacttgga gaaagctatc
    13561 gctacttgcc aaaccaggca aatcaatact ataagtcatc ggagcacgat cgaccgcaag
    13621 aagagtggga ttattctcta acaaggtctc atccactacg agaagtgctc caggatagag
    13681 gcgactgtcg ttggtagctg ttacagaaat atcacttgta tttgtcgaca agctccgctt
    13741 ctttctttcg ataacaacaa actcatcggg tagctgatta ccctctttga tgaaacgatt
    13801 ttcaatactt tctccctgat gggtcaagag tttcttttta tcgtaattca tagctagtat
    13861 aaagtcattt actgctttat ttgccatctt ctacctccta ataagttcct ggattgagtt
    13921 gcataaactc agacttgttc agcgaaatca gccgtggttg gactaagtga tccaaaattt
    13981 cctcgtacaa ttcttctgag acattgcgtc gccgtctggc tagataagaa gtcggaataa
    14041 ccgtattatc caacataaat accttatcta agtcaatcaa ggttggtctt gtaaaaggat
    14101 tacgagctag atccggctct tctatcataa agttcttgac caaacgtctg gtcaagagag
    14161 ctggtttgaa ggtctgattt ttaaccaact ctttgttttt agtcatgctg ttgtcaatac
    14221 agatatacat atgattcttc acagccaaat cgctactaat agtcggaaaa ggcaaataaa
    14281 gagctacaac atctcctctc ttaatcaagc aagagcaccc ccttttctcc taatgtaaca
    14341 tagacaggat tgaccaagtc ttctgattga ctcagaattt ccaaagtttg agtttggcgc
    14401 gctgtcaatt tagtagcatc ttgtctcttc aatacaaaat gcttgtcgcc aataaccttg
    14461 acaatataat ccttctccaa agctgactgg taaatccaca tcagatgttg tctgtcctga
    14521 gaactcaaga gagaaggatt ttcaagcctc ccgatagtct gataaaaatc aaaaacagga
    14581 gctaactcct gccaatctga ttggctagtt gtcaaggcta gaaaaagggc tttgcgagct
    14641 gatacttctt ggttagcctt gagagttact ttcccctcca agttttttag aaatcgggaa
    14701 actccagaaa gcaaattttt ctctaactgc gagaaataaa aacctttcgt tcccagacat
    14761 aagtctttca tgtcgctttc tctagcaaat aagagctcaa acatttgata gtaaaagaaa
    14821 aatatctggc actgggtcgc gctcatcttt tccttatcgg cttctttttt taaccagagc
    14881 aagggcgaca ggtaactgga ttgagacatt tcctctacct cctactcttt tttaactgga
    14941 gcatctgcac tagctgccac ttcttttgac tggatacttt cccactggtt aatctcctct
    15001 gagataagac cttcgcatgt cttgacaaat agggcaaaag ccttggtctt tcctgcatat
    15061 ttctccgttt ggcattgata gaggaatttt tctttctcca ggagttgcgc agttttttgg
    15121 taagaaatcc aattttcctt tgcattatac aaattgataa tcccctcaca cagcaagccg
    15181 agactggata aggcaaccga aatcaaacgg tagcgatcac ctggcatagg aatagcacaa
    15241 aagacagcta tgaggaaacc tgccacgatt tctgttattt ttaatacctt atagcgccta
    15301 cgatgttgaa cgcttttctt taaaaaatga gctatctgta cgtctaatcg ctctgtcagg
    15361 tacatttctt ctggcgtcat attcgtaact cctttcattt actttgataa ccatagtata
    15421 acatatttga atatcaaagt atagtaaaaa ctggactata acttattaga cttcctgcga
    15481 aacaaaatat ggtatagtag ttctatgaat tatgaagcaa gtaaacaact aactgatgca
    15541 cgatttaagc gtcttgttag tgttcagcgt accactttta aagagatgtt agctgtatta
    15601 aaaacagctt atcaaaaaag tcggacaagc tggtaaaatc ttggctgaca gtaattatca
    15661 agggctcatg aagatatatc ctcaagcaca aactccacgt aaatccagca aactcaagcc
    15721 actaacagtt gaagataaag tctataacca tgcgctatct aaggagagaa gcaaggttga
    15781 gaacatcttt gccaaagtaa aaacgtttaa aatgttttca acaacctatc gaaatcatcg
    15841 taaacgcttc ggattacgaa tgaatttgag tgctggtatt atcaatcatg aactaggatt
    15901 ctagttttgc aggaagtcta ttatatatat gcacagacat atgaaatctt tttgatacag
    15961 ccttcttttt acatagagag acagcagtta tgatatattt atccattcac aacatcttct
    16021 gtaccaatac tacaataatt ggtacatttt gattacacaa tcgtttcaaa aaatatgatg
    16081 gaagactgag tattttatag taattccctt cctatcaact agatcaacca gttgagtgtt
    16141 gaatgttgaa acaccctagc ctcagcaaag gactatgatc agcatttcct agccaatagg
    16201 acgctccaaa tcacctattc taagtccatc actagcttgg tcagtaagat acagactgca
    16261 aggcaagact gacgtggttg atgagatttt ggaagagtat tacaatcata gattcaccag
    16321 tagacttgac cgcagattta actatagtag attgaaacta gaatagtaca cttctgcttc
    16381 taaaacattg ttagaaatcg atttgactgt cctgatcaat ttgtcctgtt ctcgtttcat
    16441 tttactatac taaaaaacca cctgaaacaa atcaagtgac tagaggataa aaacaaagac
    16501 tgggcaaaaa gttttgaaaa gcaaaaaacg cataatatca ggtcttgaaa aaccttgata
    16561 ctatacgttt gattgtggga agattgactt cattttctcc tgaaattgaa gttttttcta
    16621 gtttccaggt atagacgaat tcaatatagc catctcgcta caattatttt aaccatcgaa
    16681 aaaatttttc agaatttcaa aaatttcatt ttgatctaat gaaatgtcat cattttgaag
    16741 aatagttgac ttcacaagct ctaattctat cacaaagcgg tgcatgtctg cttttaccgc
    16801 actacttgat gttatagccg ataacttttc atctcctagc aaggaagctg tcaaacgggt
    16861 aaggtcattc aaatgctttt taatggactt acttaaacct tgagcacctg tagcagagcg
    16921 ttccctcata tccagccaag ctttagcctt aaaaataatt aatactcaat gaaaatcaaa
    16981 gagcaaacta ggaagctagc tgcaggctgc tcaaaacact gttttgaggt tgtagatgga
    17041 agctgacgtg gtttgaagag attttcgaag agtatagacc acaattactc aataccgaat
    17101 acccctgaat ggtttctttt tcatgcacca atatattata ataatcttca tccaataata
    17161 aggctgataa actagcatct tggtcaaaat gtaagggaat ttctcgaccg tccttcttta
    17221 atggatattc tggtaagata ctaaatagtt caatcataga aggaaactca gaattagttg
    17281 ttgtaaatcg aaaaagctgc gctttctcat ctttctgact tccttgatac tctcccaatt
    17341 ctaaaaaatg attcaaggta gtataaaatt ccttattttt tacttcatca atgatgacca
    17401 tatcataatc ttttgttgtg cgacttttaa atccttgcga atccaatacg atagaggtag
    17461 cagttccccc aatcagaaca taatagttct gaaaatccgc aaacatttct tgaaaaataa
    17521 ctttcgtatt agctggcatc atcttctccc agatactgta atatcatatt ttctagtgct
    17581 tcactctctt cctctatacg tgggtcatca tcatctttta aggtcaaata aagagaaatc
    17641 ggatctacaa attgtttatc atgattattt ttaaaatcat tccaaaactc agatacaaaa
    17701 ggacgatatt tccatatctc tagcatcttt cattttaaaa catgctgaga aagtggcaag
    17761 gataactgat tgaattttct ctgccatatg acatagctag tattttcatc cgtttcagct
    17821 aaaaaagttg aatgcgacaa agcataagca ccaccatata gaaggttaga aacagatttt
    17881 atctgcttta tatcgccatc tggcaataaa aaggcaatcc acgttaattg ttcgctaggt
    17941 attaattcct tagggacttc agtatcattc gcattcagta ctagtcccaa tgtagggaag
    18001 aagaggtttc ccttaaagtc tacaaacgga actctagctt gaagtaattg ctttttttca
    18061 ccgtctgata acttcgaaaa caccaaaaca acatccatat tggctttatc acccatagtg
    18121 cgagcctgag taacaaatga actcaaactc ccccttctct tttctttaat caataaaaat
    18181 gattccttat gaaaagtcat ttgagtatac tcaaactttt ttacaaaact gattggtaaa
    18241 gtcaaagtca gttcctcaat actgacatca acataaaagg attgaaaaat tgacattatc
    18301 tttttgacat tcatgttttt tccttattct atcattttta ttatatttta tcattcggta
    18361 taataaaata taagtttttt gataaaataa ccaaaaacta ctcgctatcc cctctcacat
    18421 taccctacat atcgtttgac atgcgactga tagttcagga aaacttcaag gagaactttt
    18481 ctctcatcca ctatgcagga cttactattt cacttctact cctataggct caatttgaca
    18541 tttttctttt tcgaattgct catatgcctc ctgaatagtg agttcgattt atccaaattt
    18601 atttttgtct attttgatga atacttccac gaagaatgaa tttgcaccaa ttttccttct
    18661 ctttttaagc atattattcc agatatgatt gccctcttgt tcagtaataa attacgcttt
    18721 aaacgcttca atcagtatat ctcctgttgt catatgttct aaagaaaatt cttctacata
    18781 tggtttaaca tctcttaggt tattacttcc taatatccca ttatgctttt tcgctaagga
    18841 aatagatgcc ccttctcctt taccaataat cttgttacta tcatgatttc ttgttaaatc
    18901 tctatataat gcgtattctt cagttccaat gtctatgctc acaatctcag ctgaaccctt
    18961 agctaccaac tgatctatcc tagattttaa atggggaatt gtaggtatat tgatttcatc
    19021 atacacctct tgtggaataa caattttacc caaatagagc ttttctaaaa gatgttcaat
    19081 gccaacccat aaaaatactg aaatacaatc tgcatcaata aatacacgac tagtcaaacg
    19141 acaactcccc cctcttcatc tagcccatat acaatatcat atctgaaagc atctagtaac
    19201 agttcctcat acttcccttg cgaaattctg ttattttcta aaagttgttc agttgaatta
    19261 atatattatc ctaatgccat ttctttttta ctttctgaca aaggacgata taaacttgta
    19321 tcatagccta atcttgaagc tgtctctata acactaatat ccatattttt aatttcttct
    19381 gcatcaaggt atccatcatt cctcaatcta tataacatag ctttatgact gataccataa
    19441 aactgaccca attttataat atcttctact tcaagatgag ttctattggc attttctctg
    19501 atttcctcaa ccatcctata cagtgaagat gggaaaatta aaaaataaga agcaaactga
    19561 tccgcttttc tttcagtttc atctccttca ccaatcaaga taagactgac tgaactcttc
    19621 ttcacctcat cataataaag atgatacagt ccatgtgcta aagaaaatct ttacctttct
    19681 aatggcatgt ctgaattgac tgcaatgaga ctgaactgag ttcctttata acagactccg
    19741 ctaatattct ttccgagtcc ataaaatacc agcgtcaaat tttctatctt ttgtaccaat
    19801 ttaaaaatat ctatcggcga ttcaccatca gctcccaact tttttctaag atttgaagct
    19861 ttattactta aatccattcg tgatattcct ttcacctttt tccattttgg caatcatgct
    19921 ttgattcaaa gacaaatact cagcaatctt atcttgagta agatttgaag atattctaag
    19981 ttcttttatt ctttttccaa catcacatac atttatcaca tacatttatc atattcatac
    20041 acctctcata aaaagaatag cacactcttg tcataatttt ttaaataaaa aaattatgac
    20101 aaaacaagga agcaatttat tgatgctgct taaaaatcta aaattgatga gttcctatca
    20161 aaaatcgtat cttcaacctc aaaacagtac ttaaagctat ccgactcggt ttacattgtc
    20221 aaatttagat tttatttgag cataactttc tagtttgctt tctgattttt gtttaatata
    20281 gtagcaaaca ttgaaggaaa tatctccaca aaaaaacgca tactattaag ctttttcaag
    20341 acctaataat atgcgctgtt ctgatttgaa agacattcca ttattatttt actgtaatca
    20401 agccatctgg ctctactgtg aattctggct tgtctgccag tgttccgtct ggtttgaggt
    20461 agtaccagcc tgttccgtcc gctgactgga taaaggcatt tgataccatg gcgccttctt
    20521 tagcgtctaa gtagtaccaa gtgtccttgt acttgaccca gcctgtcttc atggcacctt
    20581 cttcgttgaa atagtaccac ttatcagcga ttttcttcca gcctgtagcc atttcgcctg
    20641 agttgtcgaa ccagtaccag ttgccgtctg tgtgcttcct ccagcggtct gcaagcatat
    20701 agcctgaact gtcaaagtag taccaagtgc cattgatttt ctcaaacttg tcttttggat
    20761 aagagccgtc tgaatgtacg taccagtagc cagtgtcatt cttctgccag cctgtttcaa
    20821 tcgtcaagcc gttctcaata tcatacttaa actgctcacg gctaatgccc cattttgcca
    20881 agtaagggta tggatccaca tggtctgagt ggttgtttgg ttggttattc gtgcaatact
    20941 cgtgcgtttt aattccagct aaactccctg tatcaagcgt tttcggcaaa cctgcttcat
    21001 ctgctagatt gcgtaagagt tcgatataaa ggcggtaatc cgtcatgaac tcttctttag
    21061 ttgaatggct ttcaatcagt tcaaccgctg cataggtctc agcattccaa ccgcccccaa
    21121 cgtcccaggc accattatca acaggtccta cctgcatgat gcaaccgttc ccaacaatgt
    21181 gcgagaaaaa acctaattct gggtctttcc gccagtgata atccgcttca ttctgtacgg
    21241 ttgaatgcgg attcccagtt gagtgtgcgt gtacttgcct atatggttgc acgccgactt
    21301 gaggcaaatc tgttcttaat ttactcacat taatttccat attctactcc ttatcaatta
    21361 aaacaactca ttttttacaa tccagaacca gaaactcctt tatttctacc ttacaaagaa
    21421 gacaatctta gtcacgatta ggcttgtaga tagaacctca aaacgcacta ttttgacact
    21481 gtaaatagga ctgacaaggt ctgcattcta tctacaataa caccccagac taaaaagctt
    21541 ttcaaaagta tatttttaca gtctctatat gtccttttca taaatactat actttattat
    21601 atcatataaa agaagtcaaa agtctgttaa actattttca acaccaaact aaagaagaga
    21661 acacaagttt tttcgatgtt cactagagga aatggatttt attcagtaaa tccaactagg
    21721 attgcacttt ggttgccaaa attgcctttc cttcttttat caagggatga cggaatagtg
    21781 agaagtacag ttgaactgtc atggcaaccc agataagagg ttcacaaagg ataacaccct
    21841 tatatcctgc ccaaggaata atcaaaacca caaaaacgat ttttccgatt agttcaataa
    21901 agctagaaac tagaggaagg atcttctgcc ccaagccctg caagcaattg cgataaatca
    21961 acaagaggct caaaatggga taaaaggctg aactgatttg cagatagaga cttccatttt
    22021 ctatcaagta accatctgtc gaactagcca agaaggaaac caaggctgga ctggcaaaaa
    22081 agaggaaaat acaaacaaaa actgcccagg atatacttaa acgactgccg attcgaagac
    22141 cttgaacaat gcggtcaggt cgcttagctc ctagattctg agaagcaaag gtcgtcattg
    22201 atgcagaaat agcggtcata ggaagaaggg caaaggtcat aatgcgtcga gctgccgtct
    22261 gggcactaat aatcactgca ccaaatgtat taacagaaaa ctgtaaaatc acactgccga
    22321 tagatacaat tgaactcatc aagcccatag ccaaaccttg ctccaagaga tccgcgtaca
    22381 agcttttgtc ccatttgaaa tgtttaaacc gtggcaagag ttctggcaca cttttacgaa
    22441 tataataaaa gcagagaacc gctgataaac cttgcgaaat aatggtagca agtcctgcgg
    22501 attgaactcc cagatgcaat tgcgtaataa aatagagatc cagaaccaca ttaaccaagg
    22561 cagagaaaat cagaaatccc agggctgcta gactgtcacc aatagaccgc aacaagcctg
    22621 caaaaagatt ataagcaaag ctgacaccta cacaggtcac aatcatagaa atatattgat
    22681 aagattgagg aagaatttct gcaggagtat ctaagtattg caagagagga tacaagccaa
    22741 gaaagcccag caacataact agaatgctca aaagagcacc taaaatccag gtggctgcta
    22801 ctgcttcctt gattttagtg aaattccgag ccccataata acgagcaatg acaatcccca
    22861 tgccattgcc aacaccaagt gtaaaaccta caatcaggtc aaaaatcgct gtcgtcgctc
    22921 ctactgcagc caaggattct tgaccaagaa atcgtccaac aatcaagaca tcagcagtgt
    22981 tatagagctg ttgaaaaata tttgatagca agattggaaa ggtgaagctt aagagcgagg
    23041 gaagaatcga accatgtatc aggtccactg ttcgtttttt attcataaag ctattatatc
    23101 agctttccag aggagcgaca agaaacagca aacttatata tagcggaatg aaataaggac
    23161 agtcaaatcg atttttaaca atgttttaga aatagatgtg tactattcta gtttcgatct
    23221 attatagttg gttgagtttg gaatagtacg ctgtagctgc taaaacattt ctagaaatta
    23281 atttgacttt cctaataaag ttgttcatat cttatttcaa gctactatat ataatctaaa
    23341 aacttgaatc aaaaatcgaa aaagtagcgg atttttccac tgctttaaca gcttattctt
    23401 caatttcgat ttcaagttca tcgcctaagt caagcgtaac ttcttcattc actgcttctt
    23461 ctttctttgg ctcatctttt ttgttttcag tatcttgttc tgaaacttct tctccatcaa
    23521 tcaagccaaa tttagaacgg acttgcttat caatttcatc aaagatttct gggtgctctg
    23581 ccaagtattt cttagcattc tcagaacctt gcccaatttt ttcatctttg taagaatacc
    23641 aagcccctgc ttttttgata atatccaaat cgcttgcaat cttcaaaagc tcaccagtct
    23701 tagaaattcc ttctccgtac ataatttcaa ctacggcttc cttaaacggt ggagctacct
    23761 tattttttac aaccttaatc ttagtttctt taccgacatt ggtttctttt tggtcaccag
    23821 ttcccttaat ttgtgtatta ccacgaacat ccaagcggac tgaagcatag aatttcaaag
    23881 cacgtccgcc cggtgttgtt tctggatttc caaacatcac tccaactttt tcacgcaatt
    23941 ggttgataaa aatggcaatt gttttggttt tattgataga ggcgccaagt ttacgcatgg
    24001 cctggctcat catacgagcc tgcaaaccaa catggctatc tccgatatct ccatcaattt
    24061 ccgcacgagg aacaagggca gcaactgagt cgactacgac aagatcaact gcacctgagt
    24121 caatcaattt tcccgcaatt tcaagacctt gctctcctga gtctggttga gacaagagca
    24181 attcgtcaat attgacacca agggccgcag cataagctgg atcaagggca tgttccgcat
    24241 cgataaaggc agcaatccca ccttcttttt gcgcttgtgc aactgcatga agggcaaccg
    24301 ttgtcttacc agatgactct gggccataga tttcgatgat acgtccctta ggataaccac
    24361 ctgagccaag ggcaatgtca agagctaaag aacctgagct catcacttgc accttttgct
    24421 ccgcacgttc acccaaacgc atgattgatc ctttaccaaa gtctttctca atcaatttaa
    24481 gagcgtcatt caaggccttt tcacgttctg ccccaaattt ttttgaaatt tcttctaatt
    24541 tttttggttt tttcgccatt ctattctcct acattctaat gatcctcaga cctatctact
    24601 attatatcaa aagttagtca cttaataaag ccttgcgaac taggttaaag gcatgcataa
    24661 ccgcaatatg acgtacatct gctcggcttc tgcctccaat attaaccttg ataacctcag
    24721 ttccttgctc ttgcgccaag cctatgaaga ctgtcccaac tgggtgtcct tctaggctat
    24781 ctggtcctgc cactccggtc aaactaattc caaaatcaga ctgggtcttg cttcgtgcct
    24841 gctcagccat cttctgagct gtaaattcag acaccacacc atgttcttcc aaattcttgg
    24901 caggaatatc caacatcctt gatttttcct ccaagctata ggtcacaaaa ccacccttaa
    24961 atatacttga aactccagaa aaattcgcca cggtagcttg gaaaagacct gccgtcaaac
    25021 tctctgcagc cgcgatggtt ttcccttgcc ttttcagttc ttctaccaca atgctggcta
    25081 aactagtttc ttccccataa ccatagcaaa agtctcgtaa agaaattcct tcgaaagtct
    25141 ggcagtccaa gatttgattt tccaagatat ccagcgcttg attcgcctct tcttgactgc
    25201 tagcctttgt tgacagacgt agagtgactt ctcctgtctt ggcataaggg gccaaggtag
    25261 gatcgatctg attatcaatt aaatcagcca aaatcgtaac cagctggctc tcgccaatcc
    25321 caaagaaacg aagaactcgg gaatacagct tgctccctgt catcaacttg ggtagaagtt
    25381 ggtttaagac catgggtttc aattcacttg gcggacctgg aaggacgaca taggtcactc
    25441 cgtctacttc taattttcct ccaacagcca gtcctgtttc gtttggcagt ggaatcgctc
    25501 cttctacaat ttgagcttgt ctttcgttat tcggtgttcg ggcatagtct ggtcgcaggg
    25561 caaaaaagat atccaacttc tcctgagcct gaggatcaaa gactaatgct ttccctaaaa
    25621 atttagctag ggtttgtttg gttaggtcgt cctcagttgg ccccaaaccg cctgtcaaaa
    25681 tcaccagact gctacgttga ctggcaatct caagcaaaga caagagacga acttcattgt
    25741 ctcctacagc cgtctgaaaa tatacatcta ccccaatctc agctagtttt tccgacaaaa
    25801 actgggcatt ggtgttgaca atctgtcctg tcaaaatctc tgttccaaca gcaatgattt
    25861 ctgctttcat gtttcctcct acctatctat tcgtattttt ttgaaaaaat cgcaggaatt
    25921 ttcctacgat tgattttttt atttgtatca aaagttaatt atcttcatca ccaacaggtg
    25981 ctctgccaaa taaatcttca aataaaaccg cattggtttc aagctgagta acttcttctt
    26041 gtcccaaaga acgtcggagt atattttgca tttccaacat atgtgctctc gaaacaatct
    26101 ggtaagaaac accttgaagt atctctcctt caccctgcaa ctgctgagtt tcaatggttt
    26161 taaatgaatc tttatagcct agcaagttag ggatactttt tgcagacaaa tcaatattgg
    26221 tctgcatatt gtcactcaaa gcttttagaa tctcttgata atgaccaatg ctatttaaac
    26281 tgagagcttt ttccatgact ttttgaataa cttcacgttg acgtttttga cgaccataat
    26341 ccccctcagg atcttggtaa cgcattcgtg catagactag ggcttcttct cccccaatat
    26401 gttgctcccc aacaccgata gaaatggtat taaattcttc ttggtcactg atagaaattg
    26461 ggaaacctag gatattattg actgtaatac ctcctactgc atccactaat ttttgcaacc
    26521 ctctcatatt gaccatcaca tagcgatcaa tatggatatt catcattttt tgaatggttt
    26581 ctatagcaag ctctgctcca ccatctgcat atgctgagtt cagtttcgct tcatgagcct
    26641 gaccattccc tgattcaatg cgcgtcagaa tatcccgctc taaactcatc attgttgttt
    26701 ttttcgtttt aggattcact gtcatcaaga tcatgctatc acttctaccg acccaagttt
    26761 cagttcgttc aacatttccg gtgtccactc ccattaacag aatggttaga ggttcagtcg
    26821 cttcaataac cttggtttct tcgccgattt ttttataggt tttagctaag gtttctgtcc
    26881 cttgttgata aatagtataa gcaaaaacac ctactcctac tacagttaca gaaagtaaag
    26941 ctagcaccat tccaataatt tttttaacca tatttctact aacctatcag tttacccatc
    27001 aagtaaactt cgataaattt cccttcttct atatatgccc cacgctcttg gctaccttca
    27061 atgacaaagc catgcttttg ataaagatgg actgctgctt gattacgagt ttggacagtc
    27121 agttggagac gacgcagaat gccacttgct tgtgcccact ctatcgcttc ttctagcaac
    27181 aaacttccca agccattatt ccaatatctt tttccaatca caatgaagag atctccaata
    27241 tgacggactc tcttacgctg atcagctgta atatttacaa taccagtaat tttgccattt
    27301 aagaatgcaa gtaaggttat ctgattgtcc gaactagctt gcttgttgag gaatatttcc
    27361 atctcctcac tagtcaagag aataccatct ccgtctaggc tggtaaagtc tgtctccaaa
    27421 ctcacacgat ttaaaaaggc cactaattca gctgcatctt tgggctctgc ttccctaatg
    27481 agcaattcat actccatatt gaagctcctc tgacaatttc tcagcacgca aaccctttgc
    27541 ctgaaaattt aaacggcgtc catctgcttc ttttagaatt tccaattcta aataagcatc
    27601 tggcaaggca tctcctaaga gatttcccca ctcaataaca gtcacgccgc caccaaagat
    27661 aaactcatcc aagtcgatag aatcagcatc tccttcaata cgataaacat ctaggtgata
    27721 aagtggaagt cgaccttcat actctctcac gatagtatag gtaggacttt taatcatttg
    27781 agaaatctgt aatccttttg caagtccttt agtaaaggtc gttttacctg cacccagttc
    27841 tccaattaag attaaaacat cattctttgc taatagatgg cccaaacgct cccctaaggc
    27901 ttgcaactct tcttcatttt ttatgtacat actcttatta taccaaaaac ttttcttttg
    27961 tgtctatttt cctactaaac ttatcatcat aacatccata aaaaacaggc tttctctaaa
    28021 agaaaatgag cgtaacaatg accaatacaa gatctcggaa aatatgacca taaaaggaaa
    28081 cttccttctt aaccgaattt gggacaagat aggctgcaaa aaacaagccc agtccaatat
    28141 aaatcagaag tgagacaatg gtcattggat ttcttaagaa aagaagtgtt gctaaaatag
    28201 tcaccaacac tgtctttttt ctgtccagca tagcaagaaa atcgcgcacg tattttttca
    28261 agggtaaaaa aatcagcaaa tctagcccaa ataggaaaaa gaaggatggc aataaaaagt
    28321 caactaattc ttgctgcagc gtatttttga tgaacaagtt atctgacaaa acaagaacag
    28381 ctcctaacaa attaattaag agtaacatac tgtaaaaaag cttcaccgac ttcttactgg
    28441 ctaggacact atggacttct tgcttacgag tataaagata atttactcca gcacagattc
    28501 ctgaaacgaa aaccatgctt ccgatgaaaa aagctgtact ttgtttaaag gacaagatgc
    28561 attccttcca taggaaacag ctactcaaac tgatttgaat taaagctaac aaaaataaga
    28621 ttctcattga tttcatcttc tctctccctt cctaccaatc attatactag gagaaaagag
    28681 agaactgttt ctaatcttct caaatgtctc tttaagacgc taaacaaaca ctagagacta
    28741 atactcaatg aaaatcaaag agcaaactag gtagctagcc acaggttgct caaaacactg
    28801 ttttgagatt gcagatagag ctgacgtggt ttgaagagat ttacgaagaa tataaatttg
    28861 aaatcatgaa aatccgtcaa acgggtggtt gttttgtctc gcacctcacg gagcgagacg
    28921 gactcagagt cacataatta taaggctgat agtattaatc taactatcag ccttacaggt
    28981 tatttaacgt ttcagaaaaa ctataatgtc aagattaact aaacagtatc tagttccttc
    29041 aaataatttt ctatcttcat caacattaaa ggattgttat aaatcttaca taactctctt
    29101 gcttctatat aataattttt gacttgttct ctgtctagaa atttggctcc agcatttcct
    29161 acaagaataa gtagaggagc caattggtag cttgtctgtc tttgtttaca gagttcaatc
    29221 gtttcaagag cttcttggat ggcttcatta tatttttcct ttgatactag gtagtgagcg
    29281 tagttgtaac gaactctgat gtagccaaat aaaaactctt gatggtccaa attttttgtc
    29341 tgatacaact ctattaaatg agagtagttt gcctcatatt cttgttcacg acccactaag
    29401 gaatagaaat tagatagagt attcaacgcc tttaaataaa tcagagtatt tgaagagact
    29461 tttaataata tattttccaa tgaagaaatt gcctcacact tactgtcata ttgatagaag
    29521 tcaataatag ctttaatcca ttcaaggtaa gttcggtctt ctagtgttag aaaagtactt
    29581 cgttcaatct ctattctata aatatattcc aaatcgtcat aatttctatc gtctaatagt
    29641 cgagcagaca attgcttgaa attagagagg ttagatttaa tttcaatttg ttcattaaaa
    29701 aaataatcta atggtacttc aagtcgttga gagagtttga acaaaaggtc tgcggaggga
    29761 atgaaatgcc ctctctcaat tttactaatc tgactttgtt cacaaattcc ttctgcaaga
    29821 gtttgttggg agagtctcaa ctcttttctt ttcaatctga atttctctgc gagtgtattc
    29881 attaaagata ataaaccttc ctatttgctt aattgcatta taaaattttt agttcaaaat
    29941 agcaagttaa aagaataaat aattctttat ggtaataaac taaaaaaagt caaaaattac
    30001 ataaaaatgc ttgaccgaat aatatatata tattaaaata aaaacaagga aaaagaaaag
    30061 ggtttcacga atgaagaaaa atcgtggaat tcaaaaatta gctatattag tattactagg
    30121 tgtttttatg cttagtaaca caattcctta ccaacagttt attcagaaga atagacaatt
    30181 ggagattcga gtccaatcac aaaagaagtc caatggtctt gatgttggga aggctgattg
    30241 atttcgtatt actttaaaat tcaactattt agagaaaggt attctgatga gagcttgtaa
    30301 caataccaga tagatattag taagcttgtt agtttataga gggcaggggt atttctgccc
    30361 tctgttttag aataaggaat gcactatgaa aaaattattt atactcatat ccaacctgct
    30421 tgctagtttg ttctttgttt gggtatttac catttggact gatacatatg tctcctatta
    30481 ttaccccaac gttgttgtac atgattcttc ccctgaaaca acttttcagc atgttgctac
    30541 acgcttggaa aaactagcag aagaaacaga tagctttatt gcgattcaac accaagattc
    30601 taactcagaa ggtactacag ttttttctta tacgaccttt ggggacggaa agttgcctga
    30661 tgggcttcag gaaaaaaaac tagaagatgc tcaaagtagt agtgttgaaa caaactattt
    30721 tgtattcgat ggacacctag atattcactt gctaagggag gagctaagtc aacttggctt
    30781 gactaacatg aacctgacaa ttccatctaa actatctacg ttaatggcta tctttagtaa
    30841 cggatttcag ttaatcagtc tattgatttt catcttaacc tttgtagcac tgactttaat
    30901 tagtcaaatt agccaattac ggtcgtcggg cattcgcctc atttcaggag agaaacggtg
    30961 gtccattttc cttagaccag ttggtgagga tttgaaaggg atagctgttg gtttcagttt
    31021 agctggcgtg ctcgccattc ttatgcaaaa aattctgtcg cttccaacgc aatccctaat
    31081 gaccatagga gcaggcttgc tcagttataa tctcatcttg ttgtcgatct ccctgttttt
    31141 cgctcaactc ttcgcagttg ggataaaaaa gatacacctg atgcagatta taaaagggca
    31201 agtgcctgtc agaggaatca ttagtttgat tttaatcggt caactattag cgattattat
    31261 tgtaacgctg ggaataggga gtagcttaaa gtattcccaa gcctggcaac agcatcggat
    31321 tggacaagag gcttggagtc aggaaaggca actgattacc ctatcaatca gccgtgaagg
    31381 aacgagtcct ggttttgatg aacaagctca aaggaaactc agaacttggt atcaattgat
    31441 ggatctggct gtttcagaac aaaaggcttt cttatctaga caccagttaa ttgaccgtac
    31501 tttgcaaaat ggcatggctt cctccaaaaa cttgataacc tctacagaat ggcacgatta
    31561 caacccgaat ggcaatgtcc ttatcgtcac accgcaatac ttggagcgtc aaaacattcc
    31621 tgtagataca actattgagc aaaagatgaa tcacctttat gtaggggagt ttgtcttatt
    31681 gctgcctgaa cacctccgtt cagaggaaga acattataaa tctgtttttg aagacgactt
    31741 aaccagtcgc atgtctagtc aagatgaacg acagcaaatg actgctacgg taggttattt
    31801 agaatcaggt caggatcgtt ttgtgtataa tacgacccct atttcttacc agcagttttt
    31861 gaaagatcca atcatcattg ttataacacc ccaatcaact ggtccacagt ccattttgtt
    31921 ttggatagac gcagtacaga actacgttct ctttaatcaa ttgtctgatg cccaggagct
    31981 tatccagaga caaggcattg aaaattgggt ctcagaaatg caaacaggtt accacaacta
    32041 catcacatta ttggataata ttcagaggga acgttgggta atgctagcag gagctgggct
    32101 tgggattgca acttcaatct tgttgtttaa cactatgaat aggctctact ttgaagaatt
    32161 tagacgtgcc atttttatca aacgcattgc aggtctcagg ttcttagaaa tccatcgcac
    32221 ttatctcttt gctcaactgg gtgtgttttt actgggattt gttgcgagtg tatttcttca
    32281 ggtagagata ggagttgctt tcttagtctt gttactcttt actggtctat ctcttttaca
    32341 gttacatgtc caaatgcaga aagaaaacaa gatgtccatg cttgttttga agggaggtta
    32401 atatgattga acttaaacag gtgagtaaat cttttggaga acgagagtta ttttcgaatc
    32461 tttcaatgac atttgaggct ggaaaagtct atgccttaat tggttcaagt ggtagcggaa
    32521 aaacaacctt gatgaacatg attgggaaat tagaacctta tgatgggacg attttttacc
    32581 gaggtaaaga cttggccaat tataaatcga gtgatttttt ccgtcacgaa ttgggctacc
    32641 tcttccagaa ctttggctta attgaaaacc aaagtattga agaaaacctt aagctaggtc
    32701 tcattggtca aaagttgagt cggtcggaac agcggttgag gcagaagcag gctttagaac
    32761 aggtcggcct gacttatctt gacctagata agcgcatctt tgagttatcg ggcggagaat
    32821 cgcaacgggt tgccttggca aaagttatct taaagaatcc accctttatt ctggcagatg
    32881 agccaacagc ttcaatagac ccagcaactt ctcagttgat tatggagatt ttgctatctc
    32941 ttcgagatga taataggcta atcattatcg caacacataa tccagcaatt tgggagatgg
    33001 ctgatgaagt gttcacgatg gatcgtctga aataaaaatc cttgttttta attgcacgat
    33061 gagttactga aatattatca tgaatcaata attggagtta atttagaatt gtactttatt
    33121 aatattgagg taactttttc ttgataaagg aagaaatagt ggagaggaag ttagaatgaa
    33181 aaaattcgac aattatattg ttgagaagcc ttgcgattct aattcagata aactgcaaaa
    33241 aatcttaata attgaaaatt tggtagatga tattttgcaa tttcctctca gaatcaataa
    33301 tagtgtagga gagattttcc tcctacaacc gtttcaaaag aaaactatct ttattccatg
    33361 ttattttgag gaagatattg tgaaagtcaa agatgatgat aaagttgagt ggaatttgtt
    33421 agaatttcaa aaatttagag catttttggc ttagtaatct gtgttgaagg ctcaaaacct
    33481 atggtaaaaa agtcgctttg aaaacgtatt gcctccaaag atttagttaa ataatgattt
    33541 aacacaaaaa gaaattattg aagttctgga aagatgttgt ttcagtattg agaaaaggtg
    33601 ggaaaaactt gcgattttca cagagaaagg aagaaaaagt atagaaatat agtcaattga
    33661 aacaagaaca ggacaaaaga accttttgtg ccatattttt ctcctttcgc tttacaattg
    33721 gcttgaacac ctttattgta tcgcgtttgg agtttttttg gtataacctt cgacgcgcac
    33781 ccgcatagcg ggtgtttttt tgtctcgcac ctaacggagc gagacgaact aatagtcact
    33841 taatcaaaaa acgcaccata tcaaaaacta aaaagtttga tatcatgcgt catgtcttaa
    33901 actaattgac tatactttct attcaaatga gcttttaacc aattgattga gccaatccac
    33961 tcttaaaacc aaagagcaat ttctcgctta gctgactctt ctgaatctga accatgtaca
    34021 acattttgga taacctcatt ttctccagca gcttttgcaa aatcacctcg aatagtgcct
    34081 ggtaaagctt cttctggacg agttgcaccc atcatggtcc gccaagtttc gattactttg
    34141 ggaccagaaa tgacacccac aagaactgga cctgaagtca tgaattcacg aatcggtggg
    34201 taaaaactct gaccaaccaa gtcctgatag tgctggtcaa tcaactcttc tgaaacttgt
    34261 gaacgaaact ccaatttttc gattgtaaat ccacgttgtt cgatgcgctt taacacttca
    34321 cccactagcc ctctttttac accatctggt ttgatgataa agaatgtttg ttccataccc
    34381 gtctcctttg tcagcttctt tcttttattt taccacattt cgtggaaaaa tggagaaagt
    34441 tttcagaata gagaatgaga gaacccgagg gttctctcat tctctattat tctactgttt
    34501 cttccacagt ttcaacggca gtatccacaa ctacttctgt tgtttcttca tttccttctt
    34561 cctctactgg aggattaagg tattcttctt cgttgacagc atatggttca aggttacggt
    34621 aacgggccat accagtacca gctgggatga tcttaccgat gataacattt tctttaagtc
    34681 caaggagatg gtctttctta ccacggatag ctgcgtcagt aaggacacga gttgtttcct
    34741 ggaaggaagc cgctgacaag aaactgtttg tttcaagtga ggctttggta attcccataa
    34801 ggactgggcg acctgtcgct ggaactccac ctgcgataag gacatctttg ttggcatctg
    34861 taaagtcatt gatatccatg agggtaccca tgagaagatc tgtatcacct ggatccatga
    34921 cacggacttt acggatcatt tgacgaacca ttacctcgat gtgtttgtca ccgatttcta
    34981 ccccttggct acggtaaact ttttgtactt caccgagaag gtacgtttca actgacaaga
    35041 catcacgaac tgcaaggaga cgttttggtt ggatagaacc ttctgtcaga gcagcaccac
    35101 gcgctacttg gcccccaact tcgacacgca tacgagctgt aaatggaacg acatattcac
    35161 cttcgccagt ttcaccctta acaaagactt tcttggtacg agttgatgca tcttcttcga
    35221 tagcagtaac ttgtccttta acctctgtga taaccgcttc ccctttagga ttgcgggctt
    35281 caaagatttc ttggacacga ggaagaccct gagtgatatc ggtatttgag gcaaccccac
    35341 ctgtgtggaa ggtacgcatt gtaagctgtg taccaggttc cccgatagat tgggcagcaa
    35401 tggtaccaac tgcttcacca acttcaaccg catcaccagt cgccaagttg ataccgtaac
    35461 agtgacggca gacaccgtga cgagtgttac atgtaaatac agaacggata gtcacttctt
    35521 ccacaccagc attgacaatt tcacgcgcct tgtcttctgt aatcaattca tttggaccaa
    35581 taatcactgc accagtttct ggatgtttaa cagttttctt agtgtaacga ccgttgagac
    35641 gctcttcgag agactcgatc atctcttttc cttctgcgat agaacggatc aagagaccac
    35701 ggtcagttcc acagtcgtcc tcacggatga taacgtcttg ggcaacgtcg accaaacgac
    35761 gagtcaagta acctgagtcg gctgtcttaa gggccgtatc ggtcatacct ttacgagcac
    35821 cgtgagttga gaagaacatt tccaataccg acaaaccttc gcggaagttt gaaaggattg
    35881 gcaattccat gatacgtcca ttcggagcag ccatcagacc acgcataccg gcaagctgtg
    35941 agaagtttga gatgttacca cgggctccag agtccatcat cataacgatt gggttcttag
    36001 gatcttggtt agcaatcaag cgtttctcaa gtttttcacg ggcagcacgc cattcagctg
    36061 taacagcatt gtaacgctcg tcgtctgtga tcataccacg acggaattgt ttggtgattt
    36121 gttcgacacg tttgtgtgat tcttcaatga tttcagtctt gtcatcaacg actgggatat
    36181 cggcaatacc cactgtcaat cctgcaagag ttgagtggtg gtaaccgagg ttcttcatgc
    36241 ggtcaagtag ggcagaagtt tctgtcgtac ggaaacgttt gaagatttca gcgatgatat
    36301 ttccaaggtt tttcttcttg aatggagggt tgagctcaag attgctgata gcttccttga
    36361 tatctccacc aagtggcaag aagtatttag ctggaacacc ttctgtcaag ttggcattgt
    36421 ttggttcttg caagtatggt agcccctctg gcatgatatc gttgaagaga attttaccaa
    36481 ctgttgtaag caagacctta tgtctttgct cttctgtcca aggcttgttg aggctgtctg
    36541 ttgcgatacc aacacgtgag tggaggtgaa cataaccatt gcggtaagcc ataaccgctt
    36601 cgtcacggtc tttgaagacc attccttcac cttcgcgacc agcttcttcc atggtcaagt
    36661 agtagttacc caaaaccatg tcctgagatg gagtaactac cggtttccca tctttcgggt
    36721 tcaagatgtg ctcagcagct agcatgagga tacgagcttc tgcttgtgct tcttctgaaa
    36781 gtggtacgtg gatggccatt tggtccccgt caaagtcggc attgtaggct tcacagacaa
    36841 gtgggtgcaa gcgaagagcc ttaccatcaa ttaagactgg ctcgaaggct tggataccca
    36901 aacggtgaag ggtcggtgcg cggttcaaaa gcactgggtg ttctttaatc acttcttcaa
    36961 ggatatccca gatacgctca tctccgcgtt ccaccaagcg tttagctgct ttgacgtttt
    37021 gcacgatatc acgggcaacg atttcacgca tgacaaatgg tttaaagagt tcaatcgcca
    37081 tttcacgtgg cacaccacat tggtacatct taagagttgg accaacggcg ataacggaac
    37141 gtcctgagaa gtcaacacgt ttaccgagca agttttgacg gaagcgtcct tgtttacctt
    37201 taagcatgtg gctcaatgat ttcaatggac ggctacctgg tcctgtgatt ggacgaccac
    37261 gacgaccatt gtcaatcaaa gcgtcaactg cttcttgaag catacgtttc tcattttgaa
    37321 cgatgatacc tggtgcattt aactcaagca aacgagccaa acggttgtta cggttgataa
    37381 cacggcggta aaggtcattc aagtcagatg aggcaaaacg gccaccatcc aactgcaaca
    37441 ttggacgaag atctggtggg ataaccggaa ggatgttaag aatcatccat tcaggtttgt
    37501 ttccagactt gtaaaaggca tccaaaacat ccaaacgacg gatggctttg acacgttttt
    37561 gtccagtagc tgttttcaat tcttctttga gttcagcaat ttctttttca agatctactt
    37621 gcttcaaaag gtcttggatg gcttccgcac ccatcttggc aacaaatgaa ccataaccat
    37681 attcgcgcaa gcgctctcgg tattcgcgct ctgtcatgat agacttgtgc tcaagtggtg
    37741 tatccttagg atcaatcacc acataagccg caaagtagat aacttcctcg agggcacgag
    37801 ggctcatatc aagggtcaag cccatacggc ttggaatccc cttgaagtac cagatgtgag
    37861 atacaggagc tttcaattcg atatgtccca tacgctcacg acgaactttc gtacgcgtta
    37921 cttcaacccc acagcggtca caaacaattc ctctgtaacg aatgcgtttg tacttaccac
    37981 aagcacattc ccagtctttt gtaggaccaa agatcacttc atcaaagagt ccttcacgtt
    38041 ctggtttcaa ggtacgataa ttgattgttt caggtttttt gacttctcca taagaccatg
    38101 aacggacttt acttggagaa gctagggtga tttgcatact tttaaaacga tttacatcaa
    38161 ccactatttc ttccctttct attctaagtg aactgcttat tcttgttcag cagcttcttc
    38221 tgttgcttcc gcttttgttg ctttctcagc ttcttcagct tcaaaggctg ctttagcctc
    38281 ttgggctgct ttttcgcggg ctttttcaag gtcatctacg tggatgacat cttcgtccat
    38341 tccttcatcc aagtcgcgaa gttccacttc ttggtcatct tcgtctagga cacgcatgtc
    38401 aagaccaaga gattgcaatt ctttgacaag aactcggaag gattctggaa cacctggttt
    38461 tggaattggt ttgccttttg taatagcttc ataggctttc aaacgtccgt tgatatcgtc
    38521 cgacttgtaa gtcaagattt cttgaaggac atttgacgca ccgtaggctt caagagccca
    38581 aacctccatc tcaccgaaac gttgtccacc aaactgagcc ttacctccga gtggttgttg
    38641 ggtaacagtt gagtatggtc cgactgaacg cgcgtgcaat ttatcatcaa ccatgtggtg
    38701 gagtttgatc atgtacatga ctccgacaga aacacggtta tcaaacggtt caccagtacg
    38761 tccatcgtaa aggatcgttt tggcatcgct atccatacct gcttctttaa cagttgacca
    38821 aagatcttca gaacttgctc catcaaagac tggtgtcgcg atgtgaatac caagagtacg
    38881 agctgccata ccaaggtgaa gctccataac ctgaccgata ttcatacgtg atggtacccc
    38941 aagtgggttc aacatgatgt cgactggagt tccgtctgga aggtaaggca tgtcttctac
    39001 aggaacgata cgagagacaa cccctttgtt tccgtgacgt ccggccattt tatctccgac
    39061 cttaatctta cgtttttgag cgatgtaaac acgaaccaac atgttaacac ctgattgcaa
    39121 ctcatctcca tttacacgtg taaagatctt aacatcacga acgacaccat cggcaccgtg
    39181 tggtacacga agagaagtat cacgcacttc acgagacttg tctccaaaga tagcgtgcaa
    39241 gagacgttct tcagctgaaa gatctttctc acccttaggt gttactttac ctacaagaat
    39301 atcaccttct ttaacctcag caccaatacg gataatcccc atttcgtcaa ggtctttgag
    39361 ggcatcttca ccaacgtttg gaatttcgcg agtgatttct tcaggcccaa gctttgtatc
    39421 gcgcgtttct gattcgtatt cttcaaggtg aacagatgtg tagacatcgt ccttcaccaa
    39481 gcgttcgctc atgataacgg catcctcgaa gttgtaacct tcccaagtca tgtaggcaac
    39541 gattgggttt tgtccaagcg ccatttctcc attttccata gaaggtccgt cagcgatgaa
    39601 atcgcctttt tcaacgacat caccaacttt tacgagagtg cgttggttgt aagcagtacc
    39661 tgagtttgaa cgacggaatt tttggatgtg gtaaacatcc aatgaaccat cttcacgacg
    39721 aacttctacc ttgtcagcat ctgcgtaagt aactttacca tcatactgag caatcacagc
    39781 cgcaccagaa tcgtgggctg cttggtattc cataccagta ccaacgtaag gtgcctgagg
    39841 attaatcaat ggcacagcct gacgttgcat attggctccc atgagggcac ggttggagtc
    39901 atcgttttcc aagaaaggaa tacatgctgt cgcaacggca actacctgtt ttggtgaaac
    39961 gtccatgtag tcaacaatat tagctggata ctcttggttg accccttggt gacgtcccat
    40021 gacaatcttc tcagcaaagg ttccatcttc attcagacga gagttagcct gagctacagt
    40081 atattcatct tcttcatcag ctgtcaacca aacaatttcg ttcgtgacaa cacctgtttc
    40141 acggtcaacc ttacggtatg gtgtttgaac aaaaccatat ttgttcaagt gtccgtaaga
    40201 tgacaagtta ttgatcaaac cgatgttagg tccttcaggt gtctcgattg gacacatacg
    40261 accatagtga gtgtagtgca cgtcacgtac ttcatatccg gcacggtcac gagtcaaacc
    40321 accaggtcct aaggctgaca aacggcgttt gtgagacaac tcagaaagcg ggttgtgttg
    40381 gtccatgaac tgtgacaact gtgatgaacc aaagaattct ttaactgcag ctgttacagg
    40441 acggatattg ataatttgtt gtggtgtcaa gacttcattg tcctgaacag acatacgttc
    40501 acggacatta cgttccatac gagaaagtcc caaacgtact tggttggcaa gcaattcacc
    40561 aaccgcacgg atacgacgat ttccaaggtg gtcgatatca tctacacggc caagtccttc
    40621 agccaagttg aggaagtagc tcatctcagc aaggatatct gcaggagtca ccgtacgaac
    40681 cttgtcatct gggttagcat taccaatgat cgttacgacg cgatctggat cagttggagc
    40741 aacaaccttg aatttttgaa gaacaacagg ctcagtcaca acggctgcat cgtttgggat
    40801 gtagacaatc ttgttcaagt cgccatccaa atggctttca atgctttcaa tcacgctacg
    40861 agtcataatc gtaccagctt ctaccaagat ttctccagtt tcagggtcta ccaatggctc
    40921 tgcaatggtt tggttgagca aacgtgtttt aacattgagt tttttattga ttttgtaacg
    40981 accaactgct gccaagtcat agcgacgtgg gtcaaagaag cgagccacaa gcaagctacg
    41041 tgagctttca gccgtcttag gctcacctgg acgaaggcgt tcgtaaattt ctttcaaggc
    41101 ttcgtctgta cgagagtcca ttggattctt gtggatatct ttttcaacag tgttgcgaac
    41161 caattcgctg tcaccaaaaa tatcaaagat ttcatcatca cctgagaaac caagagcacg
    41221 aaccaaggtt gtaaatggaa tcttacgagt acggtcgata cgagtgtagg tgatatcttt
    41281 tgagtcgctt tcaagttcca accaagctcc acggttaggg ataacagttg aaccatagcc
    41341 caccttacca tttttgtcta ctttgtcgtt aaagtaaaca cctggtgagc ggaccaactg
    41401 agaaacgata atacgttcac caccattgat gatgaaagta cccatttctg tcatgattgg
    41461 gaaatcacca aagaaaactt cttgggtctt gatttcgcct gtttctttat tgatcaagcg
    41521 gaaggttaca aaaattggtg ctgagtagct agcatcgtga atacgagctt cttctagcgt
    41581 gtattttggt tccttgattt catatccaac aaattccaac tccattgtgt ctgtgaagtt
    41641 tgaaattggc aatacatctt caaacacttc cttaagaccg tggtctagga aagctttgaa
    41701 tgagtcagtt tgaatttcaa tcaaatttgg taagtcaaga acttctttga ttcttgaaaa
    41761 actacgacgg gtacgatgtt tcccgtattg aacgtcatgt cctgccaaga tgattctcct
    41821 ttgtaaataa gttccaagcc ttgtcaatca ggcttttcta atcgccatat ggttgtaaac
    41881 cccttatcac cgtgtcctct tgacgaattt tcagaatctt taagcctctg ttacaaatgc
    41941 tcaaaatctt gaaaaaaagc acaaaaagag cagctaaatc tgactttttc agaagattta
    42001 actgctgtga gccttgtctg gacaatattt cagacaaaac ctacgacaaa tgattaccca
    42061 tattataccc tatttagcta gatttttcaa ggggattcag taggtttttg gtaatttttt
    42121 tcccatagaa aacttggcat cacattcgaa tcacgctatg gtacaaaaaa ctgaaaaaac
    42181 tattgactga aaatcatttt caaggtataa taataaacgt taaggcggta tagccaagtg
    42241 gtaaggcacg gctctgcaaa agcttgatcg tcggttcaaa tccgtctacc gccttctata
    42301 acttgattta tcaggtttca aatgaacaga aagcccaatt tgaagggctt tttttatttt
    42361 ccctcgaata aatacgtata actttaaaaa cttttggagc gagtttgtgg cagagttctt
    42421 tccatggcat aattcccttt tgaaatcaat tgaaaaaagc ttcgtcacgc ctggtgacaa
    42481 aagcctctag tttattctgt ttcttcttct atttcgactt ctgtgatttg gacttttacc
    42541 ttggtaacac gtccattctt cactttatca ttggttaaga taaactgttt gttttggctg
    42601 accaattcat agctgagttt ctcagtcgtt ggaatggttc ccactcctgt caaataataa
    42661 ccagcgatgg tatcaacgtc atcactttcc agttcaacat caaagtaatt attgaaatca
    42721 ttgagggtca tagttccttg aacaatgtag gtatcctcgc caatctgatg aacatctatt
    42781 gctgctttgt ccgtttcatc atcaatttca ccaacaattt cctctaagag gtcttccaaa
    42841 gtcaccaaac cagccatacc accgtattca tccagcaaga ttgccatttg tctttgggta
    42901 tttcgcagtt cttttagcaa gtcatccaca aaaatagttt caggtacaaa aagtggatct
    42961 tgtaaaattc tcttccaaac aatattgtca aaaccgtcca caaagcctgc cttaaggaga
    43021 ctcttggtgt gaatgattcc aattacattg tccttatccc catcataaac cgggatacga
    43081 gaataatttt gttttaaaat actttggata atggcttgac tatcatcctg aatatccacc
    43141 ataaaggcat ccgttcgagg caccataacc tctcgtgcca tcagttcatc gagcgaaaag
    43201 acaccttgta gcatctcaat ctcatcagca tccaatgttt cttcactatt tgtcagcata
    43261 taggcaattt catcacgggt catcttttca tccgcatcat cgaatgacat aggagtcaaa
    43321 tggctcaaga aattggtcga agcagctaaa agccaaacaa aaggactgac tagttttccg
    43381 atcccaatga taatcggcgc tgtacgaatt gccaaggcat cctttagatt aagagcgatt
    43441 ctcttaggat ataattcccc aaaaacgatg gaaatatagg tcaaaaatgc caaggataga
    43501 aaagttgcca cggcttgtgc tgtttcgcca ttcccaagcc aagaggcaat cacacgtcct
    43561 agagtatcag ttaaactcgc ccctgataag attgtaatca gggtgattcc tacctgaatg
    43621 gttgataaaa agtggttagg attttctagt accttcagca ggcggatgta gcgtctgtct
    43681 ccttcttccg ccttttgttc aactcgggca cgattaagag aaaccatggc catttctgtg
    43741 gctgagaaaa aggcatttaa taccgtcaag ataaacaata aaacaaattg tagcaacaaa
    43801 ttctgactac ttgggtcttc catagttctt ctcctaaaat agtatcttat cctttattat
    43861 atcacaaaat ttaatccaat acatattatt tttttcttag cgtaacttcc atctctctcc
    43921 caaaactgga agttagtcta agacggattt ccactgattt cacgcgtttt tctcatacta
    43981 aaagctaggt tgtgggaaac tggaagttag ttttagaagt tactattttt tcttagtacc
    44041 tattctagcc ctgcttaaac tagtaaaaag aactcctaca tccataagtg acataggagt
    44101 ttaggcttat cttttactga gttacagtta cttctccagt tcggtaatcc agttgaagtc
    44161 ccttttgaac attgggaact agaacattga attccaattc tccatccgaa gacttggctt
    44221 caatctgtga agctgaggga actaaatcct cgtttgaagc gtagtaaagg gttacacggt
    44281 aacggacacg cttgttttgg tccaaggctt tacgcacctt gctttcatag tagttttgac
    44341 cagtcgaata ctcggcttgt gcctgatttg cccaggctgt ctgaacagca atgtttttag
    44401 gattgcttgt tgaggcatca aaaccatcca aaccaccgat taaggcatag cctaacaaat
    44461 gacctctatc gactgcatgg gtataagagc cctttagatt cttgacctga tgccaacctg
    44521 gaggagtcca agaagttgaa ccattcccag tttctttacg attcttgtac tgacgagtgg
    44581 ccttagacaa gagggcatta gctacggttg gaacagtttc cttgcccact gtctttgttt
    44641 tattgtcagc gtagggctta cttgaaacct tggcatctag atttgtttta ttaccattga
    44701 cgataaaagc acctgagcca ttccactcca gactcccctt tatttgactc ttgactgcgt
    44761 ctgttaagac actctctgcc aatgcttgac taggagcttc agacgcttgt tttttctgac
    44821 taagattggt tttgggacta ttaggtgccg actgcatctg cttgatataa tagctccctg
    44881 tagacaaaag caataacact agcagtccga ttagtgtctg tcttgttttt ttgttcatat
    44941 ttctccttat ctttagaaaa aggctggttc tccagcctaa tttcctgtaa atttatgaat
    45001 caattcctgc cattttgctg gagacaggat agcccatgga tcttgaccct tgcccaagat
    45061 tccataacct accattagac cgattcctag agccagagta cctaaaatca gtactatgat
    45121 gactaaaagt aaacgattga ttacgtagct tgatttctta ttcatcttca tcgcttgcct
    45181 caatccgctg aatcttagca cctagctgcg ccaacttctc atggaaaccg tagtaacctc
    45241 tatccaagtg aaccaattta ccgaccacag tttctccctg tgctaccaaa cctgtcaaaa
    45301 tcaaggctgc actggcacga aggtcagttg aaagaacttc tgctccctgc aaaggctgtc
    45361 caccaacaat acgagctgta tcacggataa tctcagaatg caagcccatg cggcgcatct
    45421 cttctaggtg ttggaaacga ttttcgaaaa ctgtctccac catggttgat tcgccttttg
    45481 caactgtcat caaggctgta aattgagcct gcatatctgt tggaaatcct gggtggggca
    45541 aggttttcac atgaacagct tttagatttt ctagttgaga acgaacacga attccttcgt
    45601 cttcttcaat tacttcaaca cccatttcaa gtaacttggc aatcaaggga cggttgtgct
    45661 cccagacagc gtctcgaatc aagacatcac caccagtcat ggcagcagct accataaagg
    45721 ttcctgcttc gatacggtct tggactacat tgtgagtcgt accatgaagt ttctcaacac
    45781 cagtaatggt tatagtctct gtaccagcac ctttgacctt ggctcccatt tcattaagga
    45841 gaatggctaa gtcaacaatc tcaggctcac gcgcagcatt ctcaatcact gtcaccccat
    45901 cagccagagt cgctgccatc atcaagttct gcgttgcacc aacacttgga aagtccatat
    45961 agatatgagc gccatgcaag cgttctgcct tggcttcgat gtaaccagct gtctgactaa
    46021 tcttaacccc catagcttcc agacctttca aatgaagatc aataggacgg ctaccaatcg
    46081 tacaaccacc tggcatggat accttggcat gacccacacg ggcaaggatt ggccctaata
    46141 caacgatgga ggcgcgcatc ttgctgacat acttgtaagg ggcttcctca gtgatgtcgc
    46201 cagtagcatc caccttgaca agatgagctt cctcatcaaa gtcaaccttg gcattcaaac
    46261 caccaactac ctgattcata ataaagacat ccgacaaaat cggaacattc tgcaagacgg
    46321 tctttccttc acttgctaga atagtcgctg ccaacaaggg taagactgca ttttttgctc
    46381 cctcgatcgt cacgcttcct accagacgat tatcgccacc ttgaaccaca attttatcca
    46441 tactcgtttc ctttactctt gattttataa taatcctcta agcgcttctt gccacaaatg
    46501 atacaggcta ataaagaaag aactcaggat gtagcctatg acaatgctaa aaaaggctac
    46561 taataaacga acttttcttg tattatcatc tgtcactttt aaaaccttct cccatctaac
    46621 aagatccttt aaaaggtaaa aactcacata aataaagagc atatgactac ttagagtgaa
    46681 taataattga accatttgac tattatacca tcttctctgt ttgtgcgcta gtttggaaac
    46741 ttcactcaaa aattagggat tgtttttcaa gtaatcaatc gcatcttgta gggttttaac
    46801 gggcacgatt ttcatatccg tcttgattgt tttagccgct tctagggctg tttggtagtt
    46861 gtttttcgcg tccagatgcg ccttttgttc ttcttcgcta acagggttat caggagcaaa
    46921 gaaaatagca gcacctgccc tagccgaagc tacaaccttc ttatcaatac ctccaatgtc
    46981 tcccacatta ccatcgcggt caatggtacc tgtaccggca acaatacgac cattacgaag
    47041 atctgggtga gctatttgag tatagatagc tagactaaac atgagaccag cacttgggcc
    47101 gccaatacca gctgttgaaa agctaattgg gacattgctg attacctctg tacggtcaat
    47161 caagccgatt ccaattccat ttttgccatt ttccaaggtg ataatctttc cttctgcaga
    47221 cttggtttgc ccatcctctt cataggtgac cttgacggaa tcccctaatt tttgagaact
    47281 gacgtaatca atcaagtctt tggaactatc aaaggtctga tcattgactg ctgtgactgt
    47341 atcagagata ttgagaatcc ctttaaaggt tgaattatcc gtcacattca aaacataaac
    47401 tccaaagtac ttgagttcga tatccttacc agctgttttt agtccttgat acttggccat
    47461 attttgcgat gtttgcatgt agaattgatt gattcgcata aattcaacat cggaagaacc
    47521 acctgtagtc tcctgagcac tacgaatatc tgtaaaaggt gtcaaccaag cataaatcat
    47581 atgagctaaa gtggcatgtt gaacaccaac cgtaacgaat tgataggcac cagcttcctt
    47641 atcttctgtg tcatttactt taaggacttg gcgaatatct tccgaaccac ctggaacctc
    47701 tatataataa ggcaagggca ctacaaatgc caagaaagtc acaatcaagg ccgcaatgac
    47761 gtataagggc catctaatct tttttttcat ttcttatttc ctccaaaata ctctcgggaa
    47821 catggcaggc aatatcctga ccaaacttca aaagctctcg aacacctgat gaactgatat
    47881 agagatgttc aggccggcta tgtaaataaa tagtctctat atcagaagac agctgatgat
    47941 tgtagtaatc aaaactagct tcatattgca aatccgccgc attcctcaac ccccgtacta
    48001 ggaaagtagc ccccagtctt tttgcaacat cgaccaccaa ttcatcatga gaagccacga
    48061 cttcaacatt ttccaaatgt cccaaagcct tttctagccc ccgtttacga ttttcaagag
    48121 ggagaaatcc ttgtttgtgg ggattaaaaa aaatacccac ataaagctta tcaaaaagtc
    48181 tgctcgcccg ttcaatgata tccagatgcc catttgtcat cggatcaaat gagcctgtga
    48241 ataagccaat cttatctgac atagactgtc accttactaa ttccataaat cttttccttc
    48301 cagataccca gacaggcaat ctcttctgga agttcaacgg ccttatccgt ctcgcacaca
    48361 accataacat cttcagaaaa aagctctctc ttagccattt tttcaatatc tgctacgatt
    48421 tgttccttgg catagggagg gtctaagaaa acgaggtcaa attccccaga tacctgttcc
    48481 aatgccctct ctgcatccat cttgaggagt tgaaattttc caacttcctt ggtcatctgg
    48541 atattttcag ccacgatggt ctgagcctta cggtctcgct ccaccaaaac agcactggac
    48601 atgccacgcg atactgcttc gatagataaa ccaccactac ctgcataaag gtccaagact
    48661 cgtccccctt caaagtaggg accaatcatg ttaaaaatgg ctcccctaac cttatccgaa
    48721 gtaggtcttg ttgtcttgcc ttctagtgtc ttgaggggac gtcccccata gattcctgat
    48781 acgattttca tactgtttat tataccaaat tatagacaaa aagagaaaga aaaccgaacc
    48841 ttgcggttcg attctctaca aaatattttc gtaagtatcg cggacttctt gaggccaaac
    48901 acttgtttgc acttctccga tgtgtctctt gcgaagtagg aacatggcca tacgagattg
    48961 tccaattcct ccaccgattg tcaatgggaa taggccattc aacaaagact tgtgccattc
    49021 caattccaag cggtcttcat cacctgtaat ttccacctga cgtctaagag tttcttcatc
    49081 tacacgaatt cccatagaag acaactcaaa ggctccacct aaagactcat tccagacaag
    49141 aatatcacca tttagaccct tgtagccatt ctcagactcg cttgtccagt catcatagtc
    49201 tggtgcacgt ccatcgtgcg gtttaccatc tggcaactcg ccaccgatac caatcaaaaa
    49261 gacggctcca aattctttac aaatcgcatt ttcacgttct ttcggtgtca agtctgggta
    49321 gcgttctacc aattcttctg tatggataaa ggtgatttgc tttggcaaga tagactcgat
    49381 gtcatagcga gcttcaacag ctagctcagt caggcgaata gccttataaa tcttctcaac
    49441 tgtttctttt agataaacga tgttacgctt accatttggg ataaccttct cccagtccca
    49501 ctggtcaaca taaacagagt gggttgcatc caaggaatcc tcatctggac gaagggcttt
    49561 catgtggaca aagagaccct ctccttcacc aaagccaaaa cgagccaagg tgtggcgttt
    49621 ccatttagca agtgagtgca ccacttcata agtagcatca gggatttgga gaaccttgac
    49681 cgatactgga ttttccacac cagacaggtt gtcctgcatt ccgtcaccga ccttactcaa
    49741 gataggacct tgaacttcga caacttctag cttatctttc aaatactggg taaaagtgtt
    49801 tttgacaaag gaaatttctt cttgttgatg gataaaactt ttcttcatag acaactcctc
    49861 aaaaatttaa taaacgtatt atacacctat ttccaagaaa agaaaagaga aaatttaaaa
    49921 aaatcagtgt cactcaaaac actgatttca tagacctttt agtcattgcg accaaagata
    49981 cgtagaatac ttaggaaaag attgataaaa tcaagataga tgctgagagc cattgacacc
    50041 acccagcctg tcgctacacg accttgtgat tgttcatagg cgaggcgaat cttttggtta
    50101 tcccaagcaa tcaaccctga aaaaaccaaa accatggcta cgctaatcat ataatcaaag
    50161 aagccactag ccaagaaaat attgactacc atagcaatca gtaaaccaat gagagctgcc
    50221 atcattgctc gaccaatccc actcaagtct ttcttggtaa agataccaac tgccgccatg
    50281 acaaagaaga gaagggcgct cgatacaaag gcagataaaa ctgtacccgg agtatagaaa
    50341 gccaccacaa aactaagggt aaagccgttt aaaacggagt aaagtaaaaa tactggaaga
    50401 gcagctggac tatttcttga agccatgcta ctggcaacga aaaccaaagc caactccgca
    50461 aaagtagcaa tggtcaacca gagacgcccc tgcatcaaca agtaaaccaa ctgagactga
    50521 aagaccgtca acataaggcc tgataccaaa gcagatagtc cgattcccag accaacaaag
    50581 gcataaacct tagcgtaaaa ttgattgaga cctgcacggt catgtataat agtgtgattc
    50641 atccttttct ccttttctgt gaacatcttt ccttgattat aacaaaaaaa gttaaaatta
    50701 gcttaaatgg aagattaaaa taccggctgc aactgcaaca ttcaaactct cggcctgccc
    50761 cttcatgcta atatggacca actggtctgc actttcagcc ataaggggac taattccttg
    50821 accctcattt cccataacta gtacaaaatt ttctatagaa ggcagttctc tgtaatcaac
    50881 agaatcttta gatagggttg ttgctagcac tgggatagct acctttttag tttcgtcaag
    50941 aagcgctgga ctagtcatcc ggtaaatggg cagatggaaa tgactacctt gcatggaacg
    51001 tagggttttg agactgtaga tgtctgccga cttatctgaa acaatcactc ctgtaaaacc
    51061 tgctgcatcc gcagttcgaa tgatagttcc tacattaccg ggatcttgca catcttccaa
    51121 aaacaagaac ttgccctgac tcaaatcagc ttgtcctact tcttcttttt gaaccaccgc
    51181 cacaattccc tgtggagtct gagaatccgc caaatctagc aaaatatcct ctgacaccca
    51241 gacagtttgc gaaaaagtag ctaactgatc tcgataattt tctagggcaa agattttctc
    51301 aatcgtcact ccagcttgga cagcttcttc aaacaagtgc cagccttcaa tcaaataggc
    51361 agacttgcgg tatttttttt ggcgtaattt cttggcattt tttaccacag aattggcttt
    51421 tgaggttata atagtcatag aaatattata acacaatcaa agggggttgg tatgcaaaag
    51481 gttagaatga ttgcccaagg tagggtacag ggagtcggct ttcgttgggg tgtttacagc
    51541 ttggcacttg aaattggtgg catcacaggt cgagtatgga ataacgacga tggcacagtg
    51601 gaaatcttag cccaagcaga ctcatctgct atcatggcaa aatttatcca agaaatccga
    51661 aaaggaccga cacctttttc aaaagtaagc tacttagatg tcaaactaag caactttcct
    51721 ccctactctg actttaaaat cgcaaattag gtctccagaa ctattgtata ttttgtaaaa
    51781 aaacagtaga atagaaaggt ataattttta aagaaggaat aaaaacagtg aaatctatta
    51841 aacgttttgc attctcggct atgggagtgg ctatgttgct tgtcttgact ggctgtgtca
    51901 atgtcgataa aaccacaggt cagccaacag gatttatttg gaatacgatc ggagcgccta
    51961 tggctgaagc catcaagtac ttcgctactg ataaaggtct aggctttggt gtcgctatca
    52021 ttatcgtaac cattatcgta cgcttgatta tcttaccact tggtatctac caatcatgga
    52081 aggcaacgct tcactctgaa aagatgaacg ctctcaagca tgtccttgag ccacaccaaa
    52141 cacgtctcaa agaagcaact actcaagaag aaaaactcga agcccaacaa gccctctttg
    52201 ccgctcaaaa agagcacggc atcagcatgt ttggtggtgt aggatgtttc cctatcctcc
    52261 ttcaaatgcc tttcttctct gctatctact ttgctgccca acatactgaa ggggttgctc
    52321 aagcaagcta cctaggcatt cctctaggtt ctccaagtat gattttggtt gcctgtgctg
    52381 gtgtccttta ctatcttcaa tcgctccttt cacttcacgg agtagaagat gaaatgcaaa
    52441 gagaacaaat caagaaaatg atttacatga gcccactcat gatcgtcgtc ttctccctct
    52501 tctcaccagc tagtgtcaca ctttactggg ttgtcggtgg tttcatgatg attctccaac
    52561 agtttatcgt caactatatc gttcgtccaa aacttcgcaa aaaagtccgt gaagaactag
    52621 ccaagaaccc accaaaagca agtgctttct ctaaaccaag tggacgaaaa gacgttaccc
    52681 ctgaacaacc aactgctatc acaagcaaga aaaaacacaa aaatcgcaac gctggaaaac
    52741 aacgttcgag ataagaagaa aaaggcttag ctgatttgct aagtcttttt gcaaatcaaa
    52801 agcccgatgt ttccatcagg cttcttttct atccatgtac acgtttcata taatcttgat
    52861 aactttcggt atccatgagt tttttagcgt tcttgacgcg atctgctgtt ggtggtttga
    52921 ctccttcgag ggaatatgga attccaagtt cacgccactt gaactcaccc atggtgtgat
    52981 aaggtagaat ttcaaactta tcaacatttt tgagggtctt gacgaactta ccaagttcaa
    53041 tcaagtcatc atctctgtct gtcaatcctg gaactagcac gtggcgaatc cagacaggtt
    53101 ttccaatatc tgatagatac tgggcacaag ccaagatatt tttattagtt tggctagtga
    53161 caatcttgtg ctgttcttcg ttgatttcct tgatatccaa aagaaccaag tcagtgacag
    53221 ccatgagttt gtcaaacttc tcaaggtaac gtggtttatt acggaaagga agagcacagg
    53281 tatccaaggt acagtggatt ccttgttcct tagccttggt gaagagagca atcaggaaat
    53341 caatctgcaa gagagcttct cctccactga ctgtaatccc acccttattt ccccagaaac
    53401 cacggtagcg caaggcctct gtcaagacat catctaccgt ccgttcacgt gacttattgg
    53461 actccatagc ccaagtgtct gggttgtggc aatactggca acgcatgtga cagccctgca
    53521 aaaagacaat aaagcgaata ccaggcccat ctactgaccc aaagctttct gtcgaatgca
    53581 ccattcctgt cacttgtcca taatcaattg tttcttcaga catatcgtta ccttccttga
    53641 aaacgtttta tagttttatt atatcacgac ttgaaggaaa aacaagattt ttgcctattt
    53701 tttagaaagc aatctgtttt tcaatttcat tttcaatcta ttatcagatt attcttcaaa
    53761 atcgaagcca tataaggttg caaaatagtc ctcagggcgc tctgcacggc ggatttgacg
    53821 ggctttacct tcttcggtat agaggatttc cgcagaacgt aatttggcat tatactggta
    53881 gcccattgaa aatccgtggg cacctgtatc atgaattacc agcaaatcac cgatttctgt
    53941 atgaggcagt tcgcgattga ctgcaaattt atcattgttt tcacagagtg aaccaaccac
    54001 atctaccgct tcagctggtc catctggatg ggtcacgttg ctaatatgat ggtaagctcc
    54061 gtacatagct ggacgcatga ggttgactgc tgaggcatcc acacctagat aggtacggta
    54121 ggtttccttc ttatgagtca ctcttgtgac tagagcaccg tgaggtgcca gcataaaacg
    54181 acccaattcg gtgaaaatct tgacctgacc aagacctgct gacgtaagaa cttcttcata
    54241 caccttacga actccctcac caatcaaggc gatatcgttc ggctcctggt ctggacgata
    54301 attaacacca ataccgccag aaagattgat aaagtctagc gaaatgccca acttttcctt
    54361 gatttcaaca gccagttcaa agagctgacg agccaactct ggataataga gatgggtcac
    54421 ggtattggac gctaggaagg agtgaatccc aaaagtcttg gctccttttt ccttcaagat
    54481 agcaaaggct tcaaagagct ggtccttggt catgccaaac ttagcctccc caggattgtc
    54541 cataatgtct gtccccagtt caaaaacgcc tccaggatta taacgacaag agatgatttc
    54601 tggaatgcct gctactctct ccagatgttc aatatcttca aaggcatcca agttaatggt
    54661 cgcacccaat tcacgtgcat aggcgtattc cttgtctggc gtgttgttgg aagagaacat
    54721 aatctcagaa cccagaaagt ccagtttatg gctcatcaaa agctctacat aactagagca
    54781 gtccacacca caaccttctt cttggagaat tttcaaaata gctggagttg gagtagcctt
    54841 aactgcaaaa tattccttaa agcccttgtt ccacgaaaaa gcttggttga cggctcttgc
    54901 cttctcacga atccccttct catcatacaa gtgaaaggga gtcgggaact cggcaacaat
    54961 cgcttctaac tcttctctat tgataaatgg tgttttcata agcttccttc tattctgttt
    55021 gcaaagaaag gctgggacaa tcgttccaac ctttagttct atctcttatt tatcttcgtc
    55081 aaagatattg ccaacctcaa catcgatggc ttggttcttg acatcaatat tggttacctt
    55141 caagagtgac ttgtagtcaa actgcttttc acgttcttct tgggcattgt ccgcaaagac
    55201 cgctacacct gccagttctg agtcgaactc gcgcaagaga ctaatcatac cattgaccgt
    55261 tccgccacct ttcaagaagt catccacaat caagacacgg ctgcctgcct taagactacg
    55321 ttttgaaagg aacattttct cgatacggtc accacttgaa cctgaaacat agttgacgct
    55381 aacagttgaa ccttcggtaa ttttcaggtc acggcgcaca atgacaaaag agacattgag
    55441 gacattggca actgcatttg caagtggcac acccttagtt gctacggtca taaccgcgtc
    55501 aattttttgg tccataaagc ttttggcaat aatacgacca atatttttca agatggctgg
    55561 tgtgctaagc aaatcagaca gatagatata accacctggc aagatacggt cactttctga
    55621 caacttggta cgcaagtctt caaccatttc cttagcatcc tgactcgaaa tagacggtgt
    55681 gaagatgaca cctccgccag ccccagtcac tgtctggata tgaccgattt caatttcctc
    55741 aaaggcgcgt ttgataatga cgatatcttc tgagatggat gatttagcag actcatactt
    55801 ttcagcaaaa gtattgagac tagttagttt ataaggatta ttaatcaaat agttggaaat
    55861 gacaaccatc cgatcacttc ttcttaattt catttctatt tcctattcca tttttattca
    55921 aaaaatcaaa aagcaaacta gaaagctggt cgctggtggt tcaaaacact gttttgagat
    55981 tgtcaataga actgacaaac cctgtaatat acctgcatat atacatacga caaggcgata
    56041 ctaccctagt ttgaagagat tttcgaagag tattcatttt tgtcttttac ttattatacc
    56101 atattcacat aaaaaaacga acattcttat cctaaaaaat gctcattttt cttaaattat
    56161 caatctaaat ctggtttata gaaggaacga ttatccatag cgaagatttt attggtcatc
    56221 tctcctttat ccaccaaagc cagagctgtt gacatcatca tcatgcttgc atccagattg
    56281 tcaatcatat ggataatctc tgcctccata atacgtggac ggactggact tccatattca
    56341 agcaagccgt ggtgactgag gatgacatga cgaagcaaaa cgacttcttc cttggtatca
    56401 tcgatgccga gttccataac tgtcttggta atttcgctat caatgagagc gatatgtcca
    56461 agaagattac ctcgcactgt gtactctgtc tggtctggcc ccgtcaactc gataacctta
    56521 gctaagtcat gcagcataat ccccgcatag agcaggctct tattgagctg aggataaact
    56581 tcgctaatag cgtctgccaa acgtaccatg gtcgccgtat gataagccaa ccccgtttca
    56641 aaggcatggt ggttggtctt ggcagctgga taggagtaga attccttatc atacttggtg
    56701 tagagatttc ggacaatccg ttgccagaca ggattttcaa ttttgaaaat catttgcgac
    56761 atgtagtcac gaatttcctt gacatcaact ggtgacttga ccttgaaatc ggctgggtca
    56821 ttgggttcac cagcttgagg caggcggaga gtaatttgat tgacttgagg ggtattgtta
    56881 taaacttctc ggcgtccttt catgtggaca accttacctg cggtaaaggc ctcaatgtta
    56941 tgaggttggg catcccagag cttcccatca atctcgccac tatcatcttg gaaggtaaag
    57001 gctaggtagt ttttcccagc tcgagtttgc ctcaggtcag ctgatttgat taggtaaaag
    57061 ccttcaaata gctcatcttt tttcatgtga ctaatcttca tattcttcct cattttcttg
    57121 aaaatggagt agatcaagcg caggctcacc ttctgacaac tcaatgtgac ggagcgtccg
    57181 ctcgatagct atggtacgac ggtttaataa ttcatcaata ttgccagagg catgttggag
    57241 atgtttttgt gccttgacca gaataccacc aaacttgcca aactcggtct tgacactggc
    57301 aagagtcttg ctgatatggt cggcactctt ttggatatta agggtcttga aaccaactga
    57361 tagagagtta agaagggctg atagggtact tggtcctgca acaataatct gttcttcccg
    57421 tctcaaatca tcaaagaaga ccggattgcg cacaatctct gaataaagac cttctgtcgg
    57481 aacaaacaag attccaaagt tggttgtccg aggtggtgct atgtacttgt tcctaatatc
    57541 cctagcaaag cgcttgacgc ttgctaggag tgacttacga cagcgttcaa tctcatcctt
    57601 gtcacctgtc tcataggctt cttccaagcg gtaataatct gccagtggaa acttagagtc
    57661 aattggcaga tagacgtatt cttggtcgcc ttgtccgggt aacttgatgg catactccac
    57721 tcgttcacta gagttttcaa ccgttgcgta ttctcgttcg tactgggcag gtgtcatgat
    57781 gtcttcaata atttgcccca gttgcaattc tcccagaatc cctcgcgtct tggttccaga
    57841 gagaaccttg ttaagagctc cgacatcacg ggcaactgtc tgcatttctc caaggccacg
    57901 attgacagac tccagttgtt tagaaactgt ctcaaaggaa gcctgtaagc gtgtctgcaa
    57961 ggtcttttct agtttttcct cgaccgtctg gcgcatttgt tccaaacgtt gctcatttga
    58021 ttcctgcaag gcttggagac gttggtctgt cttgtctcta gtttggagga gattatctgt
    58081 catttcttga cggacttggg tcagaccttg gtgcaattca atccgcactt cttgcaaacg
    58141 gtcgctgaca accacttcca aatctttttg gtctaactgg ctggcttgtc tggcttggtc
    58201 aaagcggtaa tccaactggt ctgacaaatg atctgcctga tcctccaagc tcttacttaa
    58261 gtgtttctcc tgcctatcct gcctttgcca aatcagaaag agaccagcta gattggcaat
    58321 taataataga ataagtaaac tttccatcct acctcctgtc cttgctatgc agtacgacca
    58381 cataaccatc tgggcaagtt accgacactt ccctatctat atattcgtta gaagcgtaca
    58441 cttttttaaa gaaaaaattt tcctctgtca actcatactt ggctccaaga atagtcagct
    58501 ggctatcccg aactggcata aaggctagat agtcgtagtc tgaacgaggt tctagctgac
    58561 tgattccttc tggacaataa gtaatcaagt tttgcccatc ctcaatttct atttgatgca
    58621 tatagggtgc caacttagga ttgctaggca gaaagacatt ggccaacata tggtcaatac
    58681 ggccacccaa ggcaccgaaa atagtaacct gagcctgagg attttgctta aagatggtca
    58741 agagagccaa ttccaaatca gtatcatctt tttctggccg ggcttggaca aaatactggg
    58801 cacgtttttg aatcacctgt cgctcttctt ccgtcacaga atcaaaatct ccgactgcta
    58861 gagcaagagg caaatcttct tccaagatcc agagcgagcc tcgatccaca ccaacaaaac
    58921 catcaaagtc cgtccgataa tgaccgcggt ctccgcctgc aaaaacggca accctagtcc
    58981 agttgttttc tgagagtttg tactcgctca ttgacatctc ccttaaagac ataggaacct
    59041 gctacaaaaa cggtcgcacc agcttctttg gattgagcaa tagtttggtc atcaatccca
    59101 ccatccactt caatctcaaa gttcaaacct ttttcatcac gaagggcaac cagctcacga
    59161 accttatcca tggtttctgg cagaaaggct tgaccaccaa atccagggtt aactgtcatg
    59221 actaggactt ggtcaactag atgaagcaca tgcttaatcg cttcaactgg tgtaccagga
    59281 ttgataacaa ctgatggctt gacaccgagt gaacgaatct tttggagggc accatgaata
    59341 tgaggcgttg cttccacatg gatactaata atatccgcac ctgcacgcac aaagtcctct
    59401 aaatgatgct cagggtttga caccatcaag tggcagtcga aaaccatctt actatgagga
    59461 cgaagagctt cgaccacacc cgcaccaaaa ctgatttgcg gcacaaaatg accatccata
    59521 atatcgatat gggcatactc tgccccagtt gcttctaggc gtttaatttc acgttcaaag
    59581 ttggcataat ctgctgccag aattgacgga gcaatcttgt attgagacat aggtttctcc
    59641 ttattttgga atttttttgc tgactttttt ataggtttct ctgcgatttt caatttcgct
    59701 gaggaattgc aggtagttgt caaaacggaa gggtgcaatg gtaccttctt caactgctgg
    59761 cttgacagca caggacggct catgggtatg ggtacaagta cggaatttgc agtctcgact
    59821 gacagtggca atctctggaa aggcctgatt gaggtcttca gccgttgata cttcataatc
    59881 cagtgatgaa aagcctggtg tgtctgcgat tttaccccca ttgaggttgt aaaaactaac
    59941 agctcgagtg gtatgacgcc cgcgacccag actgtctgaa atttctcccg tttcaagatt
    60001 aagatctggt gcgattttat tgagaagagt tgatttccca acacccgtct gccccataaa
    60061 gaccgtaacc ttgcctgtta acaaaggcag gagttcctct ttactggtca caaagtcata
    60121 tccgatgtca ccataggtct gctggtaaaa atccagttct cccccgtctt ccaacaaatc
    60181 cattttagaa atatagacga tgggatgaat acccttatgc tccaaaagaa ccaagaaacg
    60241 atccagcaaa ttgctgttaa aatcaggttc cttgacagac atgattacta cagcttggtc
    60301 gatattgaca ataggcggac ggaccagact gtttttccgt tcgtgaatct tgagaatata
    60361 gccttctgaa ttttcctcgg cagagaaatc tacccagtcc ccaacgtaag gggtatgccc
    60421 ttttttacgg aaattcccac gcgcgcgtgt ttgatagact tggccatcac tctctacata
    60481 gtagaaccca gccaaggctt taatgatttg tccctgcaaa ataactcctt taaaattgtt
    60541 agttccatta taacaaaaaa aagctatttt agcttagctt ctctttacaa tttcgataag
    60601 tctattctaa aagaaaaaga tacactcacg ctttagatac caagttttat acaaaaataa
    60661 cgaatctacc tccttatata aaaacaggcg aacagagagc ctaaaactcc ctgttcgctt
    60721 tactttttct gtgtgtaata gaaaaaacct aataaagcaa gacaaaaaat atgaatataa
    60781 actccataca tcatgtgggg aaagacagac tctataaaat agcctggtag atagatgatt
    60841 ggaaattgat agaaatcata ggtcgttaga gatagtaaac aaagaacata cataaatact
    60901 gctacaatta gaacccatcc ttgctttcgc catagaaaaa tcatcaataa gaacagacaa
    60961 agtagataga ttgaccaatt tcgcaacata aattgaaaac cataaatcat actttcagtc
    61021 gtttctccat caatcacatc aactacttta tagaaaggta aacaatagct cactaaaaaa
    61081 agaaggggac taattatttt tttcatattc tctaccatgg attattttgc aagtaagctg
    61141 accatctatc tccatatcga atcaaattaa cagtataatt agttactacc cgattttcac
    61201 ctggtccaac cttagaaaaa cctgtgctat actcccaact acttcttgca cctggatgaa
    61261 accatttttg ctgggatgaa taccaaccac cttgtctaac ttccacactt gaagattcta
    61321 tttcgatatc cctttcatgg aagtcaactc ctccacttat tttagtaata tttttttgta
    61381 cacctccatc ataactcacc cagtgaacaa cagtatacaa ttccacacta taagtactat
    61441 caaactgact ttgatgagta gtaatgtttt gagtataagc gtgcactttc tgtataccaa
    61501 aaatatggtc taatatattc gttggtttag caagcttatt gtaaccctct tcaacaaaag
    61561 tagccttctc taaatcagcg gtataaacag tttttccttg tactacttga ttgtttatag
    61621 aagtaatacg gctatccaca acaatggggg ccaccatatc tccatcgcta gtttctattt
    61681 tagctgcctc tttcacctca tatacaactc gattttcttc agactgaatc acttctaccc
    61741 catttttttc aggtatagat aatctagttt gcccattaga aaccgttata tttggaccaa
    61801 tattcttctc atttgcataa gtcgcaatag gaaatcctga tagaaccact gcacacataa
    61861 ggctattgac taattttttt ctcatgaata tatccttccc attttcaaga ggagtaaaaa
    61921 tagctaatat aagatgaacg tttccttata tttcagaata ggatatctat ctgaaagcaa
    61981 ttcacactcc tataggtaac tgttccaaat cttggctaca tatatttcaa tagtttgcta
    62041 caaaaaactc ctttctaagt ctattgaaca tgcccttatt cacctactaa tatatcacaa
    62101 aaataaataa atacaagact gttttttcta ctagttttat gatagaatag tattgttagg
    62161 gtaaatttca tatataaatg tcgagtgaaa aatcgatgga gcagaaatcg gtagacaaag
    62221 actcgatttc gttggtccag ccccacaagg ctaatcaggt atttcacgag tttaaaaatc
    62281 taatgaagtg cccaatcaac tactgattca ttgatttaat acgaactata gtggattgaa
    62341 cctagaaata gtacactaag gattctaaaa cgtttctaga aattaatttg actttcctaa
    62401 tctctttgtt catatcttat ttcaatctac tatatatacc aaaatgctgg gacaaaagtc
    62461 tttaaaatca gagaaacgca tattatcagg tgttggaaaa ccttgataat atgcgtttta
    62521 tcatagaaag atctacttca ttttttacca aaattaagtt tttgtccctg catcttagag
    62581 tccttgccct ttaagtgcat ctgctaggct ggcaaactct tccaagctga gagcttcccc
    62641 acgcacactt ggtgacaagc ctgcttggtc caaagccttg gtcagcttgt ccttgacctc
    62701 ttcagtcttg ccaaagtaac ctgtcaagtt attccacaag gtcttgcggc gatgggtaaa
    62761 actagccttg gaaaccttaa agaaaaagtt ctcgtcttcc actgctacag ctggcactgg
    62821 acggcgcacc attttcaaga tggctgagtc tacatttggt gctggcacaa agactgtacg
    62881 cggcacgata aaggcaacct tggctgtcat gtaatactgc acagcgatag acaagctacc
    62941 gtaagccttg gtatttggtt gagccgagat acggtccgcc acttcttttt gcatcatgac
    63001 cacaaactca ctaaaaggaa tgccactctc gattaagtgc atgagaatag gcgttgtgat
    63061 gtagtaaggc aaattagcca ctaccttgat tggcaggtca ggatttttga aattctggat
    63121 atgttgcgcc aaatcgacct tgagaatgtc ctcgttgact acagtcacat tgtcaaaatc
    63181 acgcaaggta tctgccaaaa tcggtaccaa acgatggtcg atctcaaagg ccataacttc
    63241 tgctgcacgc tcagccaaaa actcggtcaa ggcaccaata cctggcccga tttcaatgac
    63301 attgacctgg tcatcaatct cagccgtatc cacgattttt tgtaggatat tggtatccgt
    63361 caagaaattt tgcccaaagg actttttaaa ggtaaaaccg tgacgctcca gcactgcctt
    63421 ggtcacgcta taatctgcaa ttctcatcta ttctcttttc tattatctgt tactactatt
    63481 gtaacacatt ccccttgtat tttgggggtg aaaatcatac caaaaaacta tctttcctca
    63541 tgaagaaaga tagtcttgga aatctttaaa agtggcctta gcgcttctct cgaaacatac
    63601 gtt
//
LOCUS       DAVBOD010000006        61611 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 640-05
            SAMEA1012484-rid20186543.denovo.006, whole genome shotgun sequence.
ACCESSION   DAVBOD010000006 DAVBOD010000000
VERSION     DAVBOD010000006.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012484
            Sequence Read Archive: ERR059358
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 61611)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 61611)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979948.1
            Genome Coverage       :: 595x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:03:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,266
            CDSs (total)                      :: 2,219
            Genes (coding)                    :: 2,091
            CDSs (with protein)               :: 2,091
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 71 of 128
            Pseudo Genes (incomplete)         :: 50 of 128
            Pseudo Genes (internal stop)      :: 33 of 128
            Pseudo Genes (multiple problems)  :: 22 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..61611
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012484-rid20186543.denovo.006"
                     /strain="NIG 640-05"
                     /db_xref="taxon:1313"
     gene            complement(77..922)
                     /locus_tag="VQ862_000356"
     CDS             complement(77..922)
                     /locus_tag="VQ862_000356"
                     /EC_number="3.6.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000273482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="HET3114759.1"
                     /translation="MYLIEILKSIFFGIVEGITEWLPISSTGHLILAEEFIQYQNQNE
                     AFMSMFNVVIQLGAILAVMVIYFNKLNPFKPTKDKQEVRKTWRLWLKVLIATLPLLGV
                     FKFDDWFDTHFHNMVSVALMLIIYGVAFIYLEKRNKARAIEPSVTELDKLPYTTAFYI
                     GLFQVLALLPGTSRSGATIVGGLLNGTSRSVVTEFTFYLGIPVMFGASALKIFKFVKA
                     GELLSFGQLFLLLVAMGVAFAVSMVAIRFLTSYVKKHDFTLFGKYRIVLGSVLLLYSF
                     VRLFV"
     gene            1178..2046
                     /locus_tag="VQ862_000357"
                     /pseudo
     CDS             1178..2046
                     /locus_tag="VQ862_000357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841243.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(2347..4236)
                     /locus_tag="VQ862_000358"
     CDS             complement(2347..4236)
                     /locus_tag="VQ862_000358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000750662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2207 domain-containing protein"
                     /protein_id="HET3114760.1"
                     /translation="MKKTFFLLVLGLFCLLPLSVFAIDFKINSYQGDLYIHADNTAEF
                     RQKIVYQFEEDFKGQIVGLGRAGKMPSGFDIDPHPKIQAAKNGAELADVTSEVTEEAD
                     GYTVRVYNPGQEGDIVEVDLVWNLKNLLFLYDDIAELNWQPLTDSSESIEKFEFHVRG
                     DKGAEKLFFHTGKLFRERTVEKSNLDYTIRLDNLPAKRGVELHAYWPRTDFASARDQG
                     LKGNRLEEFNKIEDSIVKEKDQSKQLLTWIFPSILSISLLLSICFYFIYRRKTAPSIK
                     YAKNHRLYEPPMELEPMVLSEAVYSTSLEEVSPLVKGAGKFTFDQLIQATLLDVIDRG
                     NVSIISEGDAVGLRLVKEDGLSSFEKDCLNLAFSGKKEETLSNLFADYKVSDSLYRRA
                     KVSDEKRIQARGLQLKSSFEEVLNQMQEGVRKRVSFWGLPDYYRPLTGLEKALQVGMG
                     VLTILPLFIGFGLFLYSLDVHGYLYLPLPILGFLGLVLSVFYYWKLRLDNRDGVLNEA
                     GAEVYYLWTSFENMLREIARLDKAELESIVVWNRLLVYATLFGYADKVSHLMKVHQIQ
                     VENPDINLYVAYGWHSMFYHSSAQMSHYASVANTASTYSVSSGSGSSGGGFSGGGGGG
                     SIGAF"
     gene            4374..5939
                     /locus_tag="VQ862_000359"
     CDS             4374..5939
                     /locus_tag="VQ862_000359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HET3114761.1"
                     /translation="MRKIYLSIFTSLLLMLGLVNVAQADEYLRIGMEAAYAPFNWTQD
                     DDSNGAVKIDGTNQYANGYDVQIAKKIAKDLGKEPLVVKTKWEGLVPALTSGKIDMII
                     AGMSPTAERKQEITFSSSYYTSEPVLLVKKDSAYASAKSLDDFNGAKITSQQGVYLYN
                     LIAQIPGAKKETAMGDFAQMRQALEAGVIDAYVSERPEALTAEAANSKFKMIQVEPGF
                     KTGEEDTAIAIGLRKNDNRISQINASIETISKDDQVALMDRMIKEQPAEATTTEETSS
                     SFFSQVAKILSENWQQLLRGAGITLLISIVGTIIGLIIGLAIGVFRTAPLSENKVIYG
                     LQKLVGWVLNVYIEIFRGTPMIVQSMVIYYGTAQAFGINLDRTLAAIFIVSINTGAYM
                     TEIVRGGILAVDKGQFEAATALGMTHNQTMRKIVLPQVVRNILPATGNEFVINIKDTS
                     VLNVISVVELYFSGNTVATQTYQYFQTFTIIAVIYFVLTFTVTRILRFIERRMDMDTY
                     TTGANQMQTEDLK"
     gene            5939..6679
                     /locus_tag="VQ862_000360"
     CDS             5939..6679
                     /locus_tag="VQ862_000360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000189492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HET3114762.1"
                     /translation="MTQAILEIKHLKKSYGQNEVLKDISLTVHKGEVISIIGSSGSGK
                     STFLRSINLLETPTDGQILYHGQNVLEKGYDLTQYREKLGMVFQSFNLFENLNVLENT
                     IVAQTTVLKRERTEAEKIAKENLEKVGMGERYWQAKPKQLSGGQKQRVAIARALSMNP
                     DAILFDEPTSALDPEMVGEVLKIMQDLAQEGLTMIVVTHEMEFARDVSHRVIFMDKGV
                     IAEEGKPEDLFTNPKEDRTKEFLQRYLK"
     gene            complement(6788..7003)
                     /locus_tag="VQ862_000361"
     CDS             complement(6788..7003)
                     /locus_tag="VQ862_000361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002893653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3114763.1"
                     /translation="MAKSNFEKVESVVGWVRDKKITGYRISKETNAREMSIIALAQGR
                     AKVKNISFETALGLIDFYEKNYEKFED"
     gene            complement(7874..9124)
                     /gene="ilvA"
                     /locus_tag="VQ862_000362"
     CDS             complement(7874..9124)
                     /gene="ilvA"
                     /locus_tag="VQ862_000362"
                     /EC_number="4.3.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine ammonia-lyase IlvA"
                     /protein_id="HET3114764.1"
                     /translation="MLSSKDIIKAHKVLNGVVVNTPLDYDHYLSEKYGAKIYLKKENA
                     QRVRSFKIRGAYYAISQLSKEERERGVVCASAGNHAQGVAYTCNEMKIPATIFMPITT
                     PQQKIGQVRFFGGDFVTIKLVGDTFDASAKAAQEFTVSENRTFIDPFDDAHVQAGQGT
                     VAYEILEEARKESIDFDAVLVPVGGGGLIAGVSTYIKETSPEIEVIGVEANGARSMKA
                     AFEAGGPVKLKEIDKFADGIAVQKVGQLTYEATRQHIKTLVGVDEGLISETLIDLYSK
                     QGIVAEPAGAASIASLEVLAEYIKGKTICCIISGGNNDINRMPEMEERALIYDGIKHY
                     FVVNFPQRPGALREFVNDILGPNDDITRFEYIKRASKGTGPVLIGIALADKHDYAGLI
                     RRMEGFDPAYINLNGNETLYNMLV"
     gene            complement(9174..9530)
                     /locus_tag="VQ862_000363"
     CDS             complement(9174..9530)
                     /locus_tag="VQ862_000363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001027901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketol-acid reductoisomerase"
                     /protein_id="HET3114765.1"
                     /translation="MNITNLFSIKTGCDETDRQLQKLFFQLDLQLGELTDQLRKLDSN
                     FVPRSQFVDTLDLNDVEYKEILNYFIFHRNDSEESLVEWLYDWISTNRYELPKEFSIR
                     MAHKYHESVTEVFGDE"
     gene            complement(9768..10004)
                     /locus_tag="VQ862_000364"
     CDS             complement(9768..10004)
                     /locus_tag="VQ862_000364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3114766.1"
                     /translation="MLADQNKADWSYDENAVINIYDDANFEDGRLHMTFEQFFKLAQI
                     AREEGLEIHSPFERADATKSARYIAKWILRNKKH"
     gene            complement(10111..11133)
                     /gene="ilvC"
                     /locus_tag="VQ862_000365"
     CDS             complement(10111..11133)
                     /gene="ilvC"
                     /locus_tag="VQ862_000365"
                     /EC_number="1.1.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketol-acid reductoisomerase"
                     /protein_id="HET3114767.1"
                     /translation="MTVQMEYEKDVKVAALDGKKIAVIGYGSQGHAHAQNLRDSGRDV
                     IIGVRPGKSFDKAKEDGFDTYTVAEATKLADVIMILAPDEIQQELYEAEIAPNLEAGN
                     AVGFAHGFNIHFEFIKVPADVDVFMCAPKGPGHLVRRTYEEGFGVPALYAVYQDATGN
                     AKNIAMDWCKGVGAARVGLLETTYKEETEEDLFGEQAVLCGGLTALIEAGFEVLTEAG
                     YAPELAYFEVLHEMKLIVDLIYEGGFKKMRQSISNTAEYGDYVSGPRVITEQVKENMK
                     AVLADIQNGKFANDFVNDYKAGRPKLTAYREQAANLEIEKVGAELRKAMPFVGKNDDD
                     AFKIYN"
     gene            complement(11199..11675)
                     /gene="ilvN"
                     /locus_tag="VQ862_000366"
     CDS             complement(11199..11675)
                     /gene="ilvN"
                     /locus_tag="VQ862_000366"
                     /EC_number="2.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002927678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase small subunit"
                     /protein_id="HET3114768.1"
                     /translation="MRRMLTAKLQNRSGVLNRFTGVLSRRQVNIESISVGATEDPNVS
                     RITIIIDVASHDEVEQIIKQLNRQIDVIRIRDITDKPHLEREVILVKMSAPAEKRAEI
                     LAIIQPFRATVVDVAPSSITIQMTGNAEKSEALLRVIRPYGIRNIARTGATGFTRD"
     gene            complement(11668..13368)
                     /locus_tag="VQ862_000367"
     CDS             complement(11668..13368)
                     /locus_tag="VQ862_000367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000411733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase large subunit"
                     /protein_id="HET3114769.1"
                     /translation="MEKISLESPKTGSDLVLETLRDLGVDTIFGYPGGAVLPFYDAIY
                     NFKGIRHILGRHEQGCLHEAEGYAKSTGKLGVAVVTSGPGATNAITGIADAMSDSVPL
                     LVFTGQVARAGIGKDAFQEADIVGITMPITKYNYQVRETADIPRIITEAVHIATTGRP
                     GPVVIDLPKDISALETDFIYSPEVNLPSYQPTLEPNDMQIKKILKQLSKAKKPVLLAG
                     GGISYAEAATELNEFAERYQIPVVTSLLGQGTIATSHPLFLGMGGMHGSFAANIAMTE
                     ADFMISIGSRFDDRLTGNPKTFAKNAKVAHIDIDPAEIGKIISADIPVVGDAKKALQM
                     LLAEPTVHNNTEKWIEKVTKDKNRVRSYDKKERVVQPQAVIERIGELTNGDAIVVTDV
                     GQHQMWTAQYYPYQNERQLVTSGGLGTMGFGIPAAIGAKIANPDKEVVLFVGDGGFQM
                     TNQELAILNIYKVPIKVVMLNNHSLGMVRQWQESFYEGRTSESVFDTLPDFQLMAQAY
                     GIKNYKFDNPETLAQDLEVITEDVPMLIEVDISRKEQVLPMVPAGKSNHEMLGVKFHA
                     "
     gene            complement(13569..15236)
                     /locus_tag="VQ862_000368"
     CDS             complement(13569..15236)
                     /locus_tag="VQ862_000368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000036655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DAK2 domain-containing protein"
                     /protein_id="HET3114770.1"
                     /translation="MSKITTSLFQEMVQAASTRLNKQAEYVNSLNVFPVPDGDTGTNM
                     GMTIENGAKEVADKPASTVGEVASILAKGLLMGARGNSGVITSQLFRGFSQAIKDKDE
                     LTGQDLALAFQSGVEVAYKAVMKPVEGTILTVSRGAAIGAKKKAEQTDDAVEVMRAAL
                     EGAKTALAKTPDMLPVLKEVGVVDSGGQGLVFIYEGFLSALTGEYIASEDFVATPANM
                     SEMINVEHHKSVAGHVATEDITFGYCTEIMVALKQGPTYAKDFDYDEFRNYLDELGDS
                     LLVVNDDEIVKVHVHTEDPGLVMQEGLKYGSLVKVKVDNMRNQHEAQVEKEATQVIKS
                     AEEKEYALIAVVAGKGLADIFCSQGVDYVIEGGQTMNPSTEDFIKAVEQVNARNIIFL
                     PNNKNIFMAAQSAAEVLEQPAVVVEARTLPQGMTSLLAFDPSKSIEENQERMTAALSD
                     VVSGSVTTAVRDTTIDGLEIHENDNLGMVDGKILVSNPDMHQTLTETLKHMLDEDSEI
                     VTFYVGEDGSEELANEIAQEIVEEFEDVEVEIHQGQQPVYPYLFSVE"
     gene            complement(15239..15604)
                     /locus_tag="VQ862_000369"
     CDS             complement(15239..15604)
                     /locus_tag="VQ862_000369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HET3114771.1"
                     /translation="MTVKINTKDGQIELTDEVIATVVGGAATEIFGVVGMASKNALKD
                     NFQALLGKENYSKGVVVKAAEDGSIAVDVYTVLSYGTKISEVSKNIQERVAFSLENQL
                     GITAQTVNVYIQNIKVVGE"
     gene            complement(15761..15949)
                     /locus_tag="VQ862_000370"
     CDS             complement(15761..15949)
                     /locus_tag="VQ862_000370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008536053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L28"
                     /protein_id="HET3114772.1"
                     /translation="MAKVCYFTGRKTVSGNNRSHAMNQTKRAVKPNLQKVTVLIDGKP
                     KKVWASARALKSGKVERV"
     gene            complement(16065..16550)
                     /locus_tag="VQ862_000371"
     CDS             complement(16065..16550)
                     /locus_tag="VQ862_000371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000656847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 8 protein"
                     /protein_id="HET3114773.1"
                     /translation="MKEEKKAIVLGADNAYMDKVETTIKSLCVHHYNLKFYVFNDDLP
                     REWFQLMEKRLETLNSEIVNVQIDSSILKGYRLPFEGLSYAAFFRYFIPKYVSESRVL
                     YLDSDIVVRKSIDELWDLDLTAIPLAAVRDDFYTHNFNSGVLLINNGMWRAENVTQDL
                     I"
     gene            complement(16819..18363)
                     /locus_tag="VQ862_000372"
     CDS             complement(16819..18363)
                     /locus_tag="VQ862_000372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011681503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 3"
                     /protein_id="HET3114774.1"
                     /translation="MNIQEEIKKRRTFAIISHPDAGKTTITEQLLYFGGEIRDAGTVK
                     GKKTGTFAKSDWMDIEKQRGISVTSSVMQFDYDGKRVNILDTPGHEDFSEDTYRTLMA
                     VDAAVMVVDSAKGIEAQTKKLFEVVKHRGIPVFTFMNKLDRDGREPLDLLQELEEILG
                     IASYPMNWPIGMGKAFEGLYDLYNQRLELYKGDERFASLEDGDKLFGSNPFYEQVKDD
                     IELLNEAGNEFSEEAILAGELTPVFFGSALTNFGVQTFLEIFLKFAPEPHGHKKTDGE
                     IVDPYDKDFSGFVFKIQANMDPRHRDRIAFVRIVSGEFERGMSVNLPRTGKGAKLSNV
                     TQFMAESRENVTNAVAGDIIGVYDTGTYQVGDTLTVGKNKFEFEPLPTFTPEIFMKVS
                     AKNVMKQKSFHKGIEQLVQEGAVQLYKNYQTGEYMLGAVGQLQFEVFKHRMESEYNAE
                     VVMNPMGKKTVRWIKPEDLDERMSSSRNILAKDRFDQPVFLFENDFALRWFADKYPDV
                     ELEEKM"
     gene            18576..18878
                     /gene="gatC"
                     /locus_tag="VQ862_000373"
     CDS             18576..18878
                     /gene="gatC"
                     /locus_tag="VQ862_000373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006147946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatC"
                     /protein_id="HET3114775.1"
                     /translation="MKITQEEVTHVANLSKLRFSEKETAAFATTLSKIVDMVELLGEV
                     DTTGVAPTTTMADRKTVLRPDVAEEGTDRDRLFKNVPEQDNYYIKVPAILDDGGDA"
     gene            18878..20344
                     /gene="gatA"
                     /locus_tag="VQ862_000374"
     CDS             18878..20344
                     /gene="gatA"
                     /locus_tag="VQ862_000374"
                     /EC_number="6.3.5.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatA"
                     /protein_id="HET3114776.1"
                     /translation="MTFNNKTIEELHNLLVSKEISATELTQATLENIKSREEALNSFV
                     TIAEEQALVQAKAIDEAGIDADNVLSGIPLAVKDNISTDGILTTAASKMLYNYEPIFD
                     ATAVANAKTKGMIVVGKTNMDEFAMGGSGETSHYGATKNAWDHSKVPGGSSSGSAAAV
                     ASGQVRLSLGSDTGGSIRQPAAFNGIVGLKPTYGTVSRFGLIAFGSSLDQIGPFAPTV
                     KENALLLNAIASEDAKDSTSAPVRIADFTSKIGQDIKGMKIALPKEYLGEGINPEVKE
                     TILNAAKHFEKLGAIVEEVSLPHSKYGVAVYYIIASSEASSNLQRFDGIRYGYRAEDA
                     TNLDEIYVNSRSQGFGEEVKRRIMLGTFSLSSGYYDAYYKKAGQVRTLIIQDFEKVFA
                     DYDLILGPTAPSVAYDLDSLNHDPVAMYLADLLTIPVNLAGLPGISIPAGFSQGLPVG
                     LQLIGPKYSEETIYQAAAAFEATTDYHKQQPVIFGGDN"
     gene            20344..21786
                     /gene="gatB"
                     /locus_tag="VQ862_000375"
     CDS             20344..21786
                     /gene="gatB"
                     /locus_tag="VQ862_000375"
                     /EC_number="6.3.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002946582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatB"
                     /protein_id="HET3114777.1"
                     /translation="MNFETVIGLEVHVELNTNSKIFSPTSAHFGNDQNANTNVIDWSF
                     PGVLPVLNKGVVDAGIKAALALNMDIHKKMHFDRKNYFYPDNPKAYQISQFDEPIGYN
                     GWIEVKLEDGTTKKIGIERAHLEEDAGKNTHGTDGYSYVDLNRQGVPLIEIVSEADMR
                     SPEEAYAYLTALKEVIQYAGISDVKMEEGSMRVDANISLRPYGQEKFGTKTELKNLNS
                     FSNVRKGLEYEIQRQAEILRSGGQIRQETRRYDEANKTTILMRVKEGAADYRYFPEPD
                     LPLFEISDEWIEEMRTELPEFPKERRARYVSDLGLSDYDANQLTANKVTSDFFEKAVA
                     LGGDAKQVSNWLQGEVAQFLNAEGKTLEQIELTPENLVEMITIIEDGTISSKIAKKVF
                     VHLAKNGGGAREYVEKAGMVQISDPAILIPIIHQVFADNEAAVADFKSGKRNADKAFT
                     GFLMKATKGQANPQVALKLLAQELAKLKEN"
     gene            21910..22953
                     /locus_tag="VQ862_000376"
     CDS             21910..22953
                     /locus_tag="VQ862_000376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000224421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-butanediol dehydrogenase"
                     /protein_id="HET3114778.1"
                     /translation="MATMKAARWHAAKDVRIQEIEVPEVLPHQVKVAVKFTGICGTDL
                     HEFLDGPIFIPTDEHVYSGQKAPVTLGHEFSGEIIEVGSDVTRVKVGDRVAVEPILAK
                     NNLVGDYNLDPNLNFVGLAADGGFAKYCVLDGDLVHVIPDSLSYEQAALTEPAAVAVY
                     AVRQSSLKAGDTAVVFGLGPIGLLIVEALRAAGASKIYAVELSPERQAKAEELGAIVV
                     RPEEGETAVEAIHRLTNGGVDVSYEVTGVPVVLGQALAAVHKAGECMVVSIWEREANI
                     NPNEFAIQEKTLKGIIAYRHIFPKVLELMEQGYFSAEKLVTKKIKLENIVEEGFIELT
                     QDKSQIKILVEPE"
     gene            23331..23891
                     /gene="efp"
                     /locus_tag="VQ862_000377"
     CDS             23331..23891
                     /gene="efp"
                     /locus_tag="VQ862_000377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000568636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P"
                     /protein_id="HET3114779.1"
                     /translation="MIEASKLKAGMTFETADGKLIRVLEASHHKPGKGNTIMRMKLRD
                     VRTGSTFDTSYRPEEKFEQAIIETVPAQYLYKMDDTAYFMNTETYDQYEIPVVNVENE
                     LLYILENSDVKIQFYGTEVIGVTVPTTVELTVAETQPSIKGATVTGSGKPATMETGLV
                     VNVPDFIEAGQKLVINTAEGTYVSRA"
     gene            23913..24302
                     /locus_tag="VQ862_000378"
     CDS             23913..24302
                     /locus_tag="VQ862_000378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HET3114780.1"
                     /translation="MGIEEQLGEIVIAPRVLEKIIAIATAKVEGVHSFSNRSVSDTLS
                     KLSLGRGIYLKNVDEELTADIYLYLEYGVKVPKVAVAIQKAVKDAVRNMADVELAAIN
                     IHVAGIVPDKTPKPELKDLFDEDFLND"
     gene            24295..24717
                     /gene="nusB"
                     /locus_tag="VQ862_000379"
     CDS             24295..24717
                     /gene="nusB"
                     /locus_tag="VQ862_000379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000203663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antitermination factor NusB"
                     /protein_id="HET3114781.1"
                     /translation="MTSPLLESRRQLRKCAFQALMSLEFGTDVETACRFAYTHDREDT
                     DVQLPAFLIDLVSGVQAKKEELDKQITQHLKAGWTIERLTLVERNLLRLGVFEITSFD
                     TPQLVAVNEAIELAKDFSDQKSARFINGLLSQFVTEEQ"
     gene            complement(24767..25003)
                     /locus_tag="VQ862_000380"
     CDS             complement(24767..25003)
                     /locus_tag="VQ862_000380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET3114782.1"
                     /translation="MDVILSAIIFGISHLILSHRDPISLLYYSLIGFFFALVYRSTDN
                     LRLTILCHSFFNFLNHAKPIWIFVYNYIYYHFFR"
     gene            complement(25016..25489)
                     /locus_tag="VQ862_000381"
     CDS             complement(25016..25489)
                     /locus_tag="VQ862_000381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001246431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3114783.1"
                     /translation="MRNTKKLRQFGIFLLIILLSTYLPQTIGLYVTIILGLGADVYSL
                     ILTMGLVGSFLLLIWRLKKKKMLFIFEKKSWNWSFVFYLFATYVVYQILGNFWARYAH
                     LINHRNIHDEYFTVLFSNGQPTFLSTILSFVLPVIIGPVFEETLDRGYFMNTFFP"
     gene            complement(25507..25692)
                     /gene="briC"
                     /locus_tag="VQ862_000382"
     CDS             complement(25507..25692)
                     /gene="briC"
                     /locus_tag="VQ862_000382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000148168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biofilm-regulating peptide BriC"
                     /protein_id="HET3114784.1"
                     /translation="MTGTNTFTVLSTEDLEQTSGGLAVWEDGYSRWLYYREFAPYMRQ
                     GALNSYIDAWKYGFRAG"
     gene            complement(25851..26618)
                     /locus_tag="VQ862_000383"
     CDS             complement(25851..26618)
                     /locus_tag="VQ862_000383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001017399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyl transferase
                     subunit alpha"
                     /protein_id="HET3114785.1"
                     /translation="MNIAKIVREAREQSRLTTLDFATGIFDEFIQLHGDRSFRDDGAV
                     VGGIGWLGDQAVTVVGIQKGKSLQDNLKRNFGQPHPEGYRKALRLMKQAEKFGRPVVT
                     FINTAGAYPGVGAEERGQGEAIARNLMEMSDLKVPIIAIIIGEGGSGGALALAVADRV
                     WMLENSIYAILSPEGFASILWKDGTRAMEAAELMKITSHELLEMDVVDKVISEIGLSS
                     KELIKSVKKELQTELARLSQKPLEELLEERYQRFRKY"
     gene            complement(26615..27481)
                     /locus_tag="VQ862_000384"
     CDS             complement(26615..27481)
                     /locus_tag="VQ862_000384"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001173351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyltransferase
                     subunit beta"
                     /protein_id="HET3114786.1"
                     /translation="MALFSKKDKYIRINPNRSVREKPQAKPEVPDELFSQCPGCKHTI
                     YQKDLGSERICPHCSYTFRISAQERLALTIDMGTFKELFTGIESKDPLHFPGYQKKLA
                     SMREKTGLHEAVVTGTALIKGQTVALGIMDSNFIMASMGTVVGEKITRLFEYATVEKL
                     PVVLFTASGGARMQEGIMSLMQMAKISAAVKRHSNVGLFYLTILTDPTTGGVTASFAM
                     EGDIILAEPQSLVGFAGRRVIENTVRESLPEDFQKAEFLLEHGFVDAIVKRRDLPDTI
                     ASLVRLHGGSPR"
     gene            complement(27518..28885)
                     /gene="accC"
                     /locus_tag="VQ862_000385"
     CDS             complement(27518..28885)
                     /gene="accC"
                     /locus_tag="VQ862_000385"
                     /EC_number="6.3.4.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000488661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="HET3114787.1"
                     /translation="MFRKILIANRGEIAVRIIRAARELGIATVAVYSTADKEALHTLL
                     ADEAVCIGPGKATESYLNINAVLSAAVLTEAEAIHPGFGFLSENSKFATMCEEVGIKF
                     IGPSGHVMDMMGDKINARAQMIKAGVPVIPGSDGEVHNSEEALIVAEKIGYPVMLKAS
                     AGGGGKGIRKVEKPDDLVSAFETASSEAKANYGNGAMYIERVIYPARHIEVQILGDEH
                     GHVIHLGERDCSLQRNNQKVLEESPSIAIGKTLRHEIGAAAVRAAEFVGYENAGTIEF
                     LLDEASSNFYFMEMNTRVQVEHPVTEFVSGVDIVKEQICIAAGQPLSVKQEDIVLRGH
                     AIECRINAENPAFNFAPSPGKITNLYLPSGGVGLRVDSAVYPGYTIPPYYDSMIAKII
                     VHGENRFDALMKMQRALYELEIEGVQTNADFQLDLISDRNVIAGDYDTSFLMETFLPK
                     YQEKE"
     gene            complement(28897..29319)
                     /gene="fabZ"
                     /locus_tag="VQ862_000386"
     CDS             complement(28897..29319)
                     /gene="fabZ"
                     /locus_tag="VQ862_000386"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HET3114788.1"
                     /translation="MIDIQGIKEALPHRYPMLLVDRVLEVSEDTIVAIKNVTINEPFF
                     NGHFPQYPVMPGVLIMEALAQTAGVLELSKPENKGKLVFYAGMDKVKFKKQVVPGDQL
                     VMTATFVKRRGTIAVVEAKAEVDGKLAASGILTFAIGN"
     gene            complement(29316..29801)
                     /locus_tag="VQ862_000387"
     CDS             complement(29316..29801)
                     /locus_tag="VQ862_000387"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001052236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein"
                     /protein_id="HET3114789.1"
                     /translation="MNLNDIKDLMTQFDQSSLREFSYKNGTDELQFSKNEARPVPEVA
                     TQVAPAPVLATPNPVAPTSAPAETVAEEVPAPAEASVASEGNLVESPLVGVVYLAAGP
                     DKPAFVTVGDSVKKGQTLVIIEAMKVMNEIPAPKDGVVTEILVSNEEMVEFGKGLVRI
                     K"
     gene            complement(29804..31039)
                     /gene="fabF"
                     /locus_tag="VQ862_000388"
     CDS             complement(29804..31039)
                     /gene="fabF"
                     /locus_tag="VQ862_000388"
                     /EC_number="2.3.1.179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000774039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase II"
                     /protein_id="HET3114790.1"
                     /translation="MKLNRVVVTGYGVTSPIGNTPEEFWNSLATGKIGIGGITKFDHS
                     DFDVHNAAEIQDFPFDKYFVKKDTNRFDNYSLYALYAAQEAVNHANLDVEALNRDRFG
                     VIVASGIGGIKEIEDQVLRLHEKGPKRVKPMTLPKALPNMASGNVAMRFGANGVCKSI
                     NTACSSSNDAIGDAFRSIKFGFQDVMLVGGTEASITPFAIAGFQALTALSTTEDPTRA
                     SIPFDKDRNGFVMGEGSGMLVLESLEHAEKRGATILAEVVGYGNTCDAYHMTSPHPEG
                     QGAIKAIKLALEEAEISPEQVAYVNAHGTSTPANEKGESGAIVAVLGKEVPVSSTKSF
                     TGHLLGAAGAVEAIVTIEAMRHNFVPMTAGTSEVSDYIEANVVYGQGLEKEIPYAISN
                     TFGFGGHNAVLAFKRWENR"
     gene            complement(31061..31792)
                     /gene="fabG"
                     /locus_tag="VQ862_000389"
     CDS             complement(31061..31792)
                     /gene="fabG"
                     /locus_tag="VQ862_000389"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-[acyl-carrier-protein] reductase"
                     /protein_id="HET3114791.1"
                     /translation="MKLEHKNIFITGSSRGIGLAIAHKFAQAGANIVLNSRGAISEEL
                     LAEFSNYGIKVVPISGDVSDFADAKRMIDQAIAELGSVDVLVNNAGITQDTLMLKMTE
                     ADFEKVLKVNLTGAFNMTQSVLKPMMKAREGAIINMSSVVGLMGNIGQANYAASKAGL
                     IGFTKSVAREVASRNIRVNVIAPGMIESDMTAILSDKIKEATLAQIPMKEFGQAEQVA
                     DLTVFLAGQDYLTGQVVAIDGGLSM"
     gene            complement(31826..32746)
                     /gene="fabD"
                     /locus_tag="VQ862_000390"
     CDS             complement(31826..32746)
                     /gene="fabD"
                     /locus_tag="VQ862_000390"
                     /EC_number="2.3.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HET3114792.1"
                     /translation="MTKTAFLFAGQGAQYLGMGRDFYDQYPIVKETIDRASQVLGYDL
                     RYLIDTEEDKLNQTRYTQPAILATSVAIYRLLQEKGYQPDMVAGLSLGEYSALVASGA
                     LDFEDAVALVAKRGAYMEEAAPADSGKMVAVLNTPVEVIEEACQKASELGVVTPANYN
                     TPAQIVIAGEVVAVDRAVELLQEAGAKRLIPLKVSGPFHTALLEPASQKLAETLAQVS
                     FSDFTCPLVGNTEAAVMQKEDIAQLLTRQVKEPVRFYESIGVMQEAGISNFIEIGPGK
                     VLSGFVKKIDQTAHLAHVEDQASLVALLEK"
     gene            complement(32739..33713)
                     /gene="fabK"
                     /locus_tag="VQ862_000391"
     CDS             complement(32739..33713)
                     /gene="fabK"
                     /locus_tag="VQ862_000391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000857459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-[acyl-carrier-protein] reductase FabK"
                     /protein_id="HET3114793.1"
                     /translation="MKTRITELLKIDYPIFQGGMAWVADGDLAGAVSKAGGLGIIGGG
                     NAPKEVVKANIDKIKSLTDKPFGVNIMLLSPFVEDIVDLVIEEGVKVVTTGAGNPSKY
                     MERFHEAGIIVIPVVPSVALAKRMEKIGADAVIAEGMEAGGHIGKLTTMTLVRQVATA
                     ISIPVIAAGGIADGEGAAAGFMLGAEAVQVGTRFVVAKESNAHPNYKEKILKARDIDT
                     TISAQHFGHAVRAIKNQLTRDFELAEKDAFKQEDPDLEIFEQMGAGALAKAVVHGDVD
                     GGSVMAGQIAGLVSKEETAEEILKDLYYGAAKKIQEEASRWAGVVRND"
     gene            complement(33832..34056)
                     /locus_tag="VQ862_000392"
     CDS             complement(33832..34056)
                     /locus_tag="VQ862_000392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000257841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HET3114794.1"
                     /translation="MAVFEKVQEIIVEELGKDASEVTLESTFDDLDADSLDLFQVISE
                     IEDAFDIQIEAENDLKTVGDLVAYVEEQAK"
     gene            complement(34116..35090)
                     /locus_tag="VQ862_000393"
     CDS             complement(34116..35090)
                     /locus_tag="VQ862_000393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketoacyl-ACP synthase III"
                     /protein_id="HET3114795.1"
                     /translation="MAFAKISQVAHYVPEQVVTNHDLAQIMDTNDEWISSRTGIRQRH
                     ISRTESTSDLATEVAKKLMAKAGITGKELDFIILATITPDSMMPSTAARVQANIGANK
                     AFAFDLTAACSGFVFALSTAEKFIASGRFQKGLVIGSETLSKAVDWSDRSTAVLFGDG
                     AGGVLLEASEQEHFLAESLNSDGSRSECLTYGHSGLHSPFSDQESADSFLKMDGRTVF
                     DFAIRDVAKSIKQTIDESPIEVTDLDYLLLHQANDRILDKMARKIGVDRAKLPANMME
                     YGNTSAASIPILLSECVEQGLIPLDGSQTVLLSGFGGGLTWGTLILTI"
     gene            complement(35090..35524)
                     /locus_tag="VQ862_000394"
     CDS             complement(35090..35524)
                     /locus_tag="VQ862_000394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HET3114796.1"
                     /translation="MDYQRINEYLTSIFNNVLVIEEVNLRGSRFKDISIKEMHTIDVI
                     GKAPDVTPSQVSKELMVTLGTVTTSLNNLERKGYIERVRSEQDRRVVHLHLTKKGRLI
                     HRLHKRFHKAMVEKIIDGMSEEEIAVMGKGLTNLYQFLEDLK"
     gene            complement(35618..36403)
                     /locus_tag="VQ862_000395"
     CDS             complement(35618..36403)
                     /locus_tag="VQ862_000395"
                     /EC_number="4.2.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-CoA hydratase"
                     /protein_id="HET3114797.1"
                     /translation="MEHIIYQLEEDLAILTLNRPEVANGFHIPMCEEILEALTLAEEN
                     PAVHFILINANGKVFSVGGDLVEMKRAVDEDDIPSLTKIAELVNTISYKIKQIAKPVL
                     MEVDGAVAGAAANMAVAADFCLATDKAKFIQAFVGVGLAPDAGGIHLLSRSIGVTRAA
                     QLAMTGEALTAEKALEWGLVYRVSEAEKLEKTREQLLKKLRRASSNSYAAIKKLVWES
                     QFKDWQGYATLELNLQKSLAQTEDFKEGVRAHSERRRPKFTGK"
     gene            36728..38092
                     /locus_tag="VQ862_000396"
     CDS             36728..38092
                     /locus_tag="VQ862_000396"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004251870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate kinase"
                     /protein_id="HET3114798.1"
                     /translation="MKVVKFGGSSLASASQLEKVLNIVKSDSERRFVVVSAPGKRNAE
                     DTKVTDALIKYYRDYVAGNDISKSQSWIIDRYAAMVSELGLKPAVLEKISKSIHALAT
                     LPIEENEFLYDTFLAAGENNNAKLIAAYFNQNGIDARYMHPREAGIVVTSEPGHARII
                     PSSYDKIEELTNTNEVLVIPGFFGVTKENQICTFSRGGSDITGSIIAAGVKADLYENF
                     TDVDGIFAAHPGIIHQPHSIPELTYREMRELAYAGFSVLHDEALLPAYRGKIPLVIKN
                     TNNPDHPGTRIVLKHSNDEFPVVGIAGDSGFVSINMSKYLMNREVGFGRKVLQILEEL
                     NIGWEHMPTGIDDLSIILRSRQLTPIKEEEILRQLVQKAKVDHAEIEHDLSIIMIVGE
                     KMKSHIGVTATATRALSENKINIQMMSQGSSEVSIMFVVNKDQEKAAIKALYNAFFGE
                     SKED"
     gene            38095..38466
                     /locus_tag="VQ862_000397"
     CDS             38095..38466
                     /locus_tag="VQ862_000397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000079352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF956 family protein"
                     /protein_id="HET3114799.1"
                     /translation="MAQSLNKTVLLSTTGTSYLSIAGKVGKFLVGDQALEFYPDVNVE
                     QFIQIPWSHINQIGANVTGCKISRHFEVFTDKGKFLFASKDSGAILKIARDKLGNDKV
                     VKLPTLIQTISQKFKNLFAKK"
     gene            38680..39954
                     /gene="serS"
                     /locus_tag="VQ862_000398"
     CDS             38680..39954
                     /gene="serS"
                     /locus_tag="VQ862_000398"
                     /EC_number="6.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000884256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine--tRNA ligase"
                     /protein_id="HET3114800.1"
                     /translation="MLDIKRIRTDFEAVAEKLATRGVDAAVLNEMKEIDAKRRNILVK
                     VETLKAERNTVSAEIAQAKRNKENTDDKIAAMQNLSAEVKALDAELAEIDAKLTEFTT
                     TLPNIPADSVPVGADEDDNVEVRRWGTPREFDFEPKAHWDLGEDLGILDWERGGKVTG
                     ARFLFYKGLGARLERAIYNFMLDEHGKEGYTEVITPYIVNHDSMFGTGQYPKFKEDTF
                     ELSDTNFVLIPTAEVPLANYYRDEILDGKDLPIYFTAMSPSFRSEAGSAGRDTRGLIR
                     LHQFHKVEMVKFAKPEESYEELEKMTANAENILQKLNLPYRVVALSTGDMGFSAAKTY
                     DLEVWIPAQNNYREISSCSNTEDFQARRAQIRYRDEADGKVKLLHTLNGSGLAVGRTV
                     AAILENYQNEDGSVTIPEALRPYMGGAEVIKP"
     gene            complement(39979..40878)
                     /locus_tag="VQ862_000399"
     CDS             complement(39979..40878)
                     /locus_tag="VQ862_000399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000735961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TDT family transporter"
                     /protein_id="HET3114801.1"
                     /translation="MKKLPLVFSGCLLGLAGAGNLILDTLPVLSHLFSLTGLVLWIYF
                     LILHLFNWKETKQELTKPPLLSGMATFPMAGMILSTYVFRVFSYLPLVAQGIWWFSFL
                     LDLTLIAGFTIKFACSGRRVHATPSWTVLYVGIAVAALTYPLVGIIEIAYATLSFGFL
                     LTFYLYPLIYSDLKKHPLPLALLGQEGIYCAPFSLLLASLVRVGGTSLPNWVLIVMIL
                     ASQSFFFFVLTRLPNILKQGFQPAFSALTFPTIITATSLKMAQGILKLPFLDYLVLAE
                     TIICLTILFFVLGAYLIWLRKKV"
     gene            complement(40988..41536)
                     /locus_tag="VQ862_000400"
     CDS             complement(40988..41536)
                     /locus_tag="VQ862_000400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000206764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxymuconolactone decarboxylase family
                     protein"
                     /protein_id="HET3114802.1"
                     /translation="MTTFTIHTVESAPAEVKEILETVEKDNNGYIPNLIGLLANAPTV
                     LEAYQIVSSIHRRNSLTPVEREVVQITAAVTNGCAFCVAGHTAFSIKQIQMNDDLIQA
                     LRNRTPIETDPKLDTLAKFTLAVINTKGRVGDEALSEFLEAGYTQQNALDVVFGVSLA
                     ILCNYANNLANTPINPELQPYA"
     gene            complement(41754..43076)
                     /locus_tag="VQ862_000401"
     CDS             complement(41754..43076)
                     /locus_tag="VQ862_000401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:alanine symporter family protein"
                     /protein_id="HET3114803.1"
                     /translation="MLELLKSIDDFAWGPPLLILLVGTGIYLTMRLGLLQVLRLPKAF
                     QLIFIQDKGHGDVSSFAALCTALASTVGTGNIIGVATAIKVGGPGALFWMWMAAFFGM
                     ATKYAEGLLAIKYRTKDDHGAVAGGPMHYILLGMGEKWRPLAVLFAVAGVLVALLGIG
                     TFTQVNSITESIQNTTTISPVITALVLSVFVAIAVFGGLKSISKVSTTVVPFMTIIYI
                     LGTLIVIFFNIGKIPGTIALVFTSAFSPLAAVGGFAGASVRMAIQNGVARGVFSNESG
                     LGSAPIAAAAAKTNEPVEQGLISMTGTFIDTLIICTLTGLTILVTGVWSGDLNGVALT
                     QSAFSTVFSHFGPALLTIFLVLFAFTTILGWNYYGERCFEFLFGVRFIWLYRVVFVLM
                     VLLGGFIELDMVWIIADIVNALMALPNLIALLVLSQVVIAETKKYFDK"
     regulatory      complement(43167..43255)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00504"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="glycine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="glycine"
                     /db_xref="RFAM:RF00504"
     gene            complement(43419..45755)
                     /locus_tag="VQ862_000402"
     CDS             complement(43419..45755)
                     /locus_tag="VQ862_000402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
                     /protein_id="HET3114804.1"
                     /translation="MNKKILETLEFDKVKALFEPHLLTEQGLEQLRQLAPTAKADKIK
                     QAFAEMKEMQALFVEQPHFTILSTKEIAGVCKRLEMGADLNIEEFLLLKRVLLASREL
                     QNFYANLENVSLEELALWFEKLHDFPQLQGNLQAFNDAGFIENFASEELARIRRKIHD
                     SESQVRDVLQDLLKQKAQMLTEGIVASRNGRQVLPVKNTYRNKIAGVVHDISASGNTV
                     YIEPREVVKLSEEIASLRADERYEMLRILQEISERVRPHAAEIANDAWIIGHLDLIRA
                     KVRFIQERQAVVPQLSENQEIQLLHVCHPLVKNAVANDVYFGQDLTAIVITGPNTGGK
                     TIMLKTLGLTQVMAQSGLPILADKGSRVGIFEEIFADIGDEQSIEQSLSTFSSHMTNI
                     VDILGKVNQHSLLLLDELGAGTDPQEGAALAMAILEDLRLRQIKTMATTHYPELKAYG
                     IETAFVQNASMEFDTATLRPTYRFMQGVPGRSNAFEIAKRLGLSEVIVGDASQQIDQD
                     NDVNRIIEQLEEQTLESRKRLDNIREVEQENLKMNRALKKLYNELNREKETELNKARE
                     QAAEIVDMALSESDQILKNLHSKSQLKPHEIIEAKAKLKKLAPEKVDLSKNKVLQKAK
                     KKRAPKVGDDIVVLSYGQRGTLTSQLKDGRWEAQVGLIKMTLEEKEFDLVQAQQEKPV
                     KKKQVNVVKRTSGRGPQARLDLRGKRYEEAMNELDTFIDQALLNNMAQVDIIHGIGTG
                     VIREGVTKYLQRNKHVKSFGYAPQNAGGSGATIVTFKG"
     gene            complement(45859..46407)
                     /locus_tag="VQ862_000403"
     CDS             complement(45859..46407)
                     /locus_tag="VQ862_000403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000622948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CvpA family protein"
                     /protein_id="HET3114805.1"
                     /translation="MISFLLLLVLVWGFYIGYRRGLLLQVYYLISAMASAFMAGQFYK
                     GLGEQFHLLLPYANSQEGQGTFFFPSDQLFQLDKVFYAGIGYLLVFGIVYSIGRLLGL
                     LLHLIPSKKLGGKLFQVSAGILSMLVTLFVLQMALTILATIPMAVIQNPLEKSIVAKH
                     IIQSIPVTTSWLKQIWVTNLIG"
     gene            complement(46404..46706)
                     /gene="zapA"
                     /locus_tag="VQ862_000404"
     CDS             complement(46404..46706)
                     /gene="zapA"
                     /locus_tag="VQ862_000404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein ZapA"
                     /protein_id="HET3114806.1"
                     /translation="MANLNRFKFTFGKKSLTLTSEHDNLFMEEIAKVATEKYQAIKEQ
                     MPSADDETIALLLAVNCLSTQLSREIEFDDKEQELEELRHKLVTCKQEQSKIEDSL"
     gene            46793..47665
                     /locus_tag="VQ862_000405"
     CDS             46793..47665
                     /locus_tag="VQ862_000405"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HIII"
                     /protein_id="HET3114807.1"
                     /translation="MASITLTPSEKDIQAFLEHYQTSLAPSKNPYIRYFLKLPQATVS
                     IYTSGKILLQGEGAEKYASFFGYQAVEQTSGQNLPLIGTDEVGNGSYFGGLAVVAAFV
                     TPDQHDFLRKLGVGDSKTLTDQKIRQIAPILKEKIQHQALLLSPSKYNEVIGDRYNAV
                     SVKVALHNQAIYLLLQKGVQPEKIVIDAFTSAKNYDKYLAQEANRFSNSISLEEKAEG
                     KYLAVAVSSVIARDLFLENLENLGRELGYQLPSGAGTASDKVASQILQAYGMQGLNFC
                     AKLHFKNTEKAKNA"
     gene            47677..48291
                     /gene="lepB"
                     /locus_tag="VQ862_000406"
     CDS             47677..48291
                     /gene="lepB"
                     /locus_tag="VQ862_000406"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001048155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HET3114808.1"
                     /translation="MNLFKNFLKEWGLFLLILSLLALSRIFFWSNVRVEGHSMDPTLA
                     DGEILFVVKHLPIDRFDIVVAHEEDGNKDIVKRVIGMPGDTIRYENDKLYINDKETDE
                     PYLADYIKRFKDDKLQSTYSGKGFEGNKGTFFRSIAQKAQAFTVDVNYNTNFSFTVPE
                     GEYLLLGDDRLVSSDSRHVGTFKAKDITGEAKFRLWPITRIGTF"
     gene            48419..50785
                     /locus_tag="VQ862_000407"
     CDS             48419..50785
                     /locus_tag="VQ862_000407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000454449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RecD-like DNA helicase"
                     /protein_id="HET3114809.1"
                     /translation="MEVYFSGTIERIIFENPSNFYRILLLEIDDTDAEDFDDFEIIVT
                     GTMADVIEGEDYTFWGQIVQHSKYGEQLQISRYDRAKPTSKGLVKYFSSSHFKGIGLK
                     TAQKIVDTYGENTIDEILQHPEKLEGIAGFSAKNREAFVSTLRLNYGTEMVLSKLANY
                     GIPNKLAFQIQDFYKEETLDVVENYPYQLVEDIKGLGFTIADQLAEELGIESQAPERF
                     RAGLVHSLFQACMETGDTYVEARDLLEQTLTLLESSRPVELDPSQVAQELSYLIEEDK
                     VQQIDTKIFDNSLFFAEEGIRSHLIRILEKGKQKSQDLETIQKHITTVEQELGIEYDN
                     IQKQAICDAIQNKVFILTGGPGTGKTTVINGIIAVYALLEGLDLRKKSNLPILLAAPT
                     GRAARRMNELTGLPSATIHRHLGMTGDDDTSHLEDYLDADFIIVDEFSMVDTWLANQL
                     FSNISSNSKILIVGDSDQLPSVSPGQVLADLLHIPLIPQTRLEKIYRQSKESTIVTLA
                     SQIRQGILPADFTQKKADRSYFEIASGHIPATIEKILGVALRNGIPARDIQVLAPMYR
                     GTAGIDAINQLMQDLLNPPQKDQLSFEAPQCHYRKRDKVIHLVNDAEINVFNGDLGAI
                     TDLIPGKYTESKQDEIVIDFDGNEVSYPRNEWYKIRLAYAMSIHKSQGSEFPVVILPI
                     TSASRRMLERNLIYTAITRAKSKLILLGELQAFDYATQHIGTARKTYLIERFSDLLEN
                     VEEKQQAVSETVTSSASEQSYILTEENWDRIPAMIGITDTDLKEIFGK"
     gene            complement(50833..52116)
                     /locus_tag="VQ862_000408"
     CDS             complement(50833..52116)
                     /locus_tag="VQ862_000408"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trigger factor"
                     /protein_id="HET3114810.1"
                     /translation="MSVSFENKETNRGVLTFTISQDQIKPELDRVFKSVKKSLNVPGF
                     RKGHLPRPIFDKKFGEESLYQDVMNALLPNAYEAAVKEAGLEVVAQPKIDVTSMEKGQ
                     DWVIAAEVVTKPEVKLGDYKNLEVSVDVEKEVTDADVEERIERERNNLAELVIKEAAA
                     ENGDTVVIDFVGSIDGVEFDGGKGENFSLGLGSGQFIPGFEDQLVGHSAGETVDVIVT
                     FPEDYQAEDLAGKEAKFVTTIHEVKAKEVPALDDELAKDIDEEVETLADLKEKYRKEL
                     AAAKEEAYKDAVEGAAIDTAVENAEIVELPEEMIHEEVHRSVNEFLGNLQRQGINPDM
                     YFQITGTTQEDLHNQYQAEAESRTKTNLVIEAVAKAEGFDASEEEIQKEVEQLAADYN
                     MEVAQVQNLLSADMLKHDITIKKAVELITSTATVK"
     gene            complement(52277..52669)
                     /locus_tag="VQ862_000409"
     CDS             complement(52277..52669)
                     /locus_tag="VQ862_000409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HET3114811.1"
                     /translation="MDSPKSLASYRVIGISDRVLEILKEYLLLEEGDYIFTNNGSPLM
                     ITCFNYFLKNSFRKSEIKKDDFVLTAHVFRYSHISLLAELEVPITAIMDRVDYTNETK
                     ILSVYTHVTEKMKSNITEKLDKLVLEND"
     gene            complement(52968..53597)
                     /locus_tag="VQ862_000410"
     CDS             complement(52968..53597)
                     /locus_tag="VQ862_000410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine protease"
                     /protein_id="HET3114812.1"
                     /translation="MVLSKYYGVADGMNVEGRGSANFIKDNVLITAAHNYYRHDYGKE
                     ADDIYVLPAVSPSQELFGKIKVKEVRYLKEFRNLNSKDAREYDLALLILEEPIGAKLG
                     TLGLPTSQKNLTGITVTITGYLSYNFKIHQMYTDKKQVLSDDGMFLDYQVDTLEGSSG
                     STVYDASHRVVGVHTLGDGANQINSAVKLNERNLPFIYSVLKGYSLEGW"
     gene            complement(53642..53881)
                     /locus_tag="VQ862_000411"
     CDS             complement(53642..53881)
                     /locus_tag="VQ862_000411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000754500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3114813.1"
                     /translation="MKKTVYKKLGISIIASTLLASQLSTVSALSVISSTGEEYEVSET
                     LEKGPESNDSSLSEISPTYGSYYQKQSEVLSVMMI"
     gene            complement(54031..54297)
                     /locus_tag="VQ862_000412"
                     /pseudo
     CDS             complement(54031..54297)
                     /locus_tag="VQ862_000412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000060522.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
     gene            complement(54322..54633)
                     /locus_tag="VQ862_000413"
     CDS             complement(54322..54633)
                     /locus_tag="VQ862_000413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
                     /protein_id="HET3114814.1"
                     /translation="MDWDFADTCWEKDPREYQYVAANYLKAMQSYLKETDLPKLEQLV
                     VTKSWWDTVDILDRVVGSLVYEHSELEEIILILFENLFKPRQLYLQPQNSVLSNLRLA
                     S"
     gene            complement(54558..54800)
                     /locus_tag="VQ862_000414"
     CDS             complement(54558..54800)
                     /locus_tag="VQ862_000414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
                     /protein_id="HET3114815.1"
                     /translation="MSLADLLEELEAAKDSKKARSMEAYMRHQFSFLGIAVPERNKLY
                     KNIFQKRKKQRLSIGILQTLAGKRILENTNMWLLTI"
     gene            complement(54801..55433)
                     /locus_tag="VQ862_000415"
     CDS             complement(54801..55433)
                     /locus_tag="VQ862_000415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET3114816.1"
                     /translation="MKILLVDDHEMVRLGLKSYFDLQDDVEVVGEASNGSQGIDLALE
                     LRPDVIVMDIVMPEMNGIDATLAILKEWPEAKILIVTSYLDNEKIMPVLDAGAKGYML
                     KTSSADELLHAVSKVAAGELAIEQEVSKKVEYHRNHMELHEELTARERDVLQLIAKGY
                     ENQRIADDLFISLKTVKTHVSNILAKLEVSDRTQAAVYAFQHHLVGQEEF"
     gene            complement(55447..56442)
                     /locus_tag="VQ862_000416"
     CDS             complement(55447..56442)
                     /locus_tag="VQ862_000416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HET3114817.1"
                     /translation="MKKQAYVIIALTSFLFVFFFSHSLLEILDFDWSIFLHDVEKTEK
                     FVFLLLVFSMSITCLLALFWRGIEELSLRKMQANLKRLLAGQEVVQVADPDLDASFKS
                     LSGKLNLLTEALQKAENHSLAQEEEIIEKERKRIARDLHDTVSQELFAAHMILSGISQ
                     QALKLDREKMQIQLQSVTAILETAQKDLRVLLLHLRPVELEQKSLIEGIQILLKELED
                     KSDLRVSLKQNMTKLPKKIEEHIFRILQELISNTLRHAQASCLDVYLYQTDVELQLKV
                     VDNGIGFQLGSLDDLSYGLRNIKERVEDMAGTVQLLTAPKQGLAVDIRIPLLDKE"
     gene            complement(56439..57137)
                     /locus_tag="VQ862_000417"
     CDS             complement(56439..57137)
                     /locus_tag="VQ862_000417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001224647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-active antibiotics response protein"
                     /protein_id="HET3114818.1"
                     /translation="MRKFKIFLFIEACLLTGALILMVSEHFSRFLLILFLFLLLIRYY
                     TGKEGNNLLLVAATILFFFIVMLNPFVILAIFVAVIYSLFLLYPMMNQEKEQTNLVFE
                     EVVTVKKEKNRWFGNLHHFSSYQTCQFDDINLFRFMGKDTIHLERVILTNHDNVIILR
                     KMVGTTKIIVPVDVEVSLSVNCLYGDLTFFNQPKRALRNEHYHQETKDYLKSNKSVKI
                     FLTTMIGDVEVVRG"
     gene            complement(57214..58224)
                     /locus_tag="VQ862_000418"
     CDS             complement(57214..58224)
                     /locus_tag="VQ862_000418"
                     /EC_number="5.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000210649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 2 isopentenyl-diphosphate Delta-isomerase"
                     /protein_id="HET3114819.1"
                     /translation="MTTNRKDEHILYALEQKSSYNSFDEVELIHSSLPLYNLDEIDLS
                     TEFAGRKWDFPFYINAMTGGSNKGREINQKLAQVAESCGILFVTGSYSAALKNPTDDS
                     FSVKSSHPNLLLGTNIGLDKPVELGLQTVEEMNPVLLQVHVNVMQELLMPEGERKFRS
                     WQSHLADYSEQIPVPIVLKEVGFGMDAKTIERAYEFGVRTVDLSGRGGTSFAYIENRR
                     SGQRDYLNQWGQSTMQALLNAQEWKDKVELLVSGGVRNPLDMIKCLVFGAKSVGLSRT
                     VLELVETYTVEEVIGIVQGWKADLRLIMCSLNCATIADLQKVDYLLYGKLKEAKDQMK
                     KA"
     gene            complement(58208..59215)
                     /locus_tag="VQ862_000419"
     CDS             complement(58208..59215)
                     /locus_tag="VQ862_000419"
                     /EC_number="2.7.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000562378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomevalonate kinase"
                     /protein_id="HET3114820.1"
                     /translation="MIAVKTCGKLYWAGEYAILEPGQLALIKDIPIYMRAEIAFSDSY
                     RIYSDMFDFAVDLRPNPDYSLIQETIALMGDFLAVRGQNLRPFSLKICGKMEREGKKF
                     GLGSSGSVVVLVVKALLALYNLSVDQNLLFKLTSAVLLKRGDNGSMGDLACIVAEDLV
                     LYQSFDRQKVAAWLEEENLATVLERDWGFFISQVKPTLECDFLVGWTKEVAVSSHMVQ
                     QIKQNINQNFLSSSKETVVSLVEALEQGKAEKVIEQVEVASKLLEGLSTDIYTPLLRQ
                     LKEASQDLQAVAKSSGAGGGDCGIALSFDAQSTETLKNRWADLGIELLYQERIGHDDK
                     S"
     gene            complement(59202..60155)
                     /gene="mvaD"
                     /locus_tag="VQ862_000420"
     CDS             complement(59202..60155)
                     /gene="mvaD"
                     /locus_tag="VQ862_000420"
                     /EC_number="4.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000373478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diphosphomevalonate decarboxylase"
                     /protein_id="HET3114821.1"
                     /translation="MDREPVTVRSYANIAIIKYWGKKKEKEMVPATSSISLTLENMYT
                     ETTLSPLPANVTADEFYINGQLQNEVEHAKMSKIIDRYRPAGEGFVRIDTQNNMPTAA
                     GLSSSSSGLSALVKACNAYFKLGLDRSQLAQEAKFASGSSSRSFYGPLGAWDKDSGEI
                     YPVETDLKLAMIMLVLEDKKKPISSRDGMKLCVETSTTFDDWVRQSEKDYQDMLIYLK
                     ENDFAKIGELTEKNALAMHATTKTASPAFSYLTDASYEAMDFVRQLREKGEACYFTMD
                     AGPNVKVFCQEKDLEHLSEIFGQRYRLIVSKTKDLSQDDCC"
     gene            complement(60137..61015)
                     /gene="mvk"
                     /locus_tag="VQ862_000421"
     CDS             complement(60137..61015)
                     /gene="mvk"
                     /locus_tag="VQ862_000421"
                     /EC_number="2.7.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mevalonate kinase"
                     /protein_id="HET3114822.1"
                     /translation="MTKKVGVGQAHSKIILIGEHAVVYGYPAISLPLLEVEVTCKVVP
                     AESPWRLYEEDTLSMAVYASLEYLDITEACIRCEIDSAIPEKRGMGSSAAISIAAIRA
                     VFDYYQADLPHDVLEILVNRAEMIAHMNPSGLDAKTCLSDQPIRFIKNVGFTELEMDL
                     SAYLVIADTGVYGHTREAIQVVQNKGKDALPFLHALGELTQQAEVAISQKDAEGLGQI
                     LSQAHLHLKEIGVSSPEADFLVETTLSHGALGAKMSGGGLGGCIIALVTNLTHAQELA
                     ERLEEKGAVQTWIESL"
     gene            complement(61137..61259)
                     /locus_tag="VQ862_000422"
     CDS             complement(61137..61259)
                     /locus_tag="VQ862_000422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein C"
                     /protein_id="HET3114823.1"
                     /translation="MTTGWFQVNGRWYYAYSSGALAVNTIVDGYSVNYNGEWVR"
BASE COUNT        18177 a        14038 c        11499 g        17897 t
ORIGIN      
        1 cagataaagc tgacgcggtt tgaagagatt ttctaagagt ataaaacctt gaagagttgc
       61 cccttcaagg tttttcttat acaaataaac ggacaaaact gtaaagtagc aaaacactac
      121 caagcacgat acggtattta ccaaaaaggg tgaagtcgtg ttttttcaca tagctggtca
      181 agaagcgaat agccaccatg ctgaccgcaa aagctactcc catcgcgacc aagagcaaaa
      241 acaattgccc aaagctcaag agttctccgg ctttcacaaa tttgaaaatc tttaaggcac
      301 tagctccaaa cataacggga atcccaagat agaaggtaaa ttctgtcaca actgaacgac
      361 tggttccatt taacaaacca ccgacaatcg ttgcacctga acggctagtc cctggtaaaa
      421 gagcaagaac ttggaagagt ccgatataga aagcggtcgt ataaggaagc ttgtccaact
      481 ctgttacact tggctcgata gcacgcgctt tattgcgctt ttccaaatag atgaaggcaa
      541 ccccgtagat aatcaacatg agagcaactg aaaccatgtt atggaagtgg gtatcaaacc
      601 aatcatcaaa tttaaagaca ccaagtaaag gcaaagtggc aatcaagacc ttcaaccata
      661 gtctccaagt cttacgaact tcctgtttgt ccttagtcgg tttaaaagga ttgagcttgt
      721 taaaataaat caccataact gctaaaatag caccaagctg aatcacgaca ttaaacatgg
      781 acataaaggc ttcattttga ttttggtatt ggataaactc ctctgctaaa atcaagtgac
      841 ctgtactgga aatcggcaac cattccgtaa ttccttcaac aatcccgaag aagatagatt
      901 ttaaaatttc aataagatac atatatttct ccttatatta tatttaacgc agttagctac
      961 tgccaaagcc caagtggtat acttggaata agccactgtg gattagttca tttcctccaa
     1021 tcgcttgacg atttccgaaa gggtctaaca acagcttttt gtttcaattg gtaatgagtt
     1081 tgataacgca tagacgtttt atctcgtcta aggtaacaag gcaaaaagtt cgtggataac
     1141 caagtagact tgaaatacta tatctggagg tactcccatg ctttatgtgg gcattgatgt
     1201 cgctaaaaat aaacacgatg ttacagcctt gaatgttcga ggaaaactgt tcttaaacca
     1261 ctcacttttt caaataataa agctggtttt gaactcttag atctgtcttt tcgacagctc
     1321 aaccaagact gtctcatcgc tcttaaactt ctttctgacc ccaatcgtga acaatttcaa
     1381 cacgataatc ggcaagtaga actaaaaata ctggctagac atattcatcg tctcaagaaa
     1441 aaacagtctg attggaaagt acaatacact cgttgtcttg atatcatctt tcctgagttg
     1501 gataaaatcg ttggaaagca ttcagaatat acctaccaac tcttgacacg ctaccctaat
     1561 cctcagaaaa ggcttgaggc aagatttgat aagctgatag aaattaagcg attgaccgct
     1621 tctaaaattc aggatatcct ctcagtcgca cctcgttcta tcggaacaac atctcctgct
     1681 cgtgaattcg aaatcatcga aatcatcaaa cattacaaga ggctcattga caaggcggaa
     1741 acatgtgtca atgacttgat ggctgagttc aactcggtca tcacgacggt tactgggatt
     1801 gggggtcgtt taggggcggt cattttagcc gagattcgaa atattcatgc ctttgataat
     1861 cctgctcaat tacaagcttt cgctggactg gattcttcta tttatcagtc aggtcagatt
     1921 gatttagctg gaagaatgat caaacggggt tcccctcatc tgcggtgggc actcatacaa
     1981 gctgccaaag catgcgctcg cttttcacct gcttttaagg cctatcttaa gactaagtta
     2041 gaataaggaa aacattacaa tgtagccatc atccaccttg caaaaaaact tatccgaacc
     2101 ctgttttata tcctaaaaaa gagctgccat ttgacgaaca aaaagtgatg taatttctga
     2161 aattaacaca ggattacctt tgaaaaaatg gactttttca agggcttttt gccgtgctct
     2221 aaaatcatcg ccaaatcatc aaattgaaat aagaaatagt ttagataaaa ctattgactt
     2281 ttcttatagt ttgtctttct tctatcttcc attatatcat actttttcag tctatggtag
     2341 ctctctttaa aaggctccga tactgccgcc acctccgcct ccagagaagc caccgccaga
     2401 acttccactt ccagaagata cggagtaggt acttgctgta tttgcgacac tagcataatg
     2461 gctcatttgc gcgcttgaat gataaaacat actgtgccag ccataagcta catagagatt
     2521 gatatctgga ttttcaactt gaatctgatg aaccttcatc aaatgactaa ccttgtccgc
     2581 atagccaaat aaggttgcat agaccaagag acgattccaa acaacaatac tttccaattc
     2641 agccttatcc agtcgtgcaa tctcacgtaa catattttca aaactggtcc agagatagta
     2701 gacctcagct cccgcttcat ttagaacacc atcacgatta tctagtcgaa gcttccaata
     2761 atagaaaaca gacaaaacta accctagaaa accaagtatt ggcaaaggga ggtaaagata
     2821 gccatgaacg tctaaactgt acaagaacaa accaaatccg ataaataggg gcaagatagt
     2881 caagacaccc atacccactt gcaaagcctt ttccaaacca gttaaaggac gatagtaatc
     2941 tgggagcccc cagaaggaaa ctcgttttct cactccttct tgcatctggt tcaatacctc
     3001 ttcaaaagaa gatttgagtt gaagccctct tgcttgaatc cgtttttcat cagaaacttt
     3061 ggctctacga taaagactat cagatacctt gtaatccgca aacaaattgg aaagagtttc
     3121 ttctttttta cctgaaaaag ctagatttag gcagtctttc tcaaagcttg acaaaccatc
     3181 ttcttttact agcctcaaac caactgcatc tccttctgaa atgatagaga cattcccacg
     3241 gtctatcaca tctagcaagg tagcttgaat aagttgatca aaggtgaatt ttccagctcc
     3301 cttgaccaag ggactcactt cctccaagga ggtcgagtag actgcttctg ataaaaccat
     3361 aggctctaat tccattgggg gttcatagag acgatgattt ttagcatatt tgattgaagg
     3421 agcggtcttt cttctataga taaaatagaa acagatgctc aataacaagg agatggaaag
     3481 gatcgaaggg aagatccaag taagtagttg tttactttga tctttttctt taacgatcga
     3541 atcctctatc ttattaaact cttctaaacg attccctttc aagccctgat ccctagcgct
     3601 agcaaaatca gttcgcggcc agtaggcatg caattcaact ccacgcttag ccggaagatt
     3661 gtctaaacga atagtataat caaggttact cttttcaacc gttctctctc taaaaagttt
     3721 ccctgtatgg aaaaagagtt tctcagcccc cttgtctccc cttacatgaa attcaaactt
     3781 ttcaatagac tctgaactat ctgtcagagg ttgccaattt aattcagcga tatcatcata
     3841 aaggaaaagt aaatttttta agttccagac gaggtcaact tcaactatgt cgccctcctg
     3901 acctggatta tagactctca cagtataacc atccgcttct tctgttactt cgctagtcac
     3961 atctgctagt tctgcaccgt ttttcgcggc ctgaatcttt ggatgagggt caatgtcaaa
     4021 cccgctaggc atcttaccag cacgtccaag tcccacgatt tggcccttaa agtcctcctc
     4081 aaactggtaa actatcttct gtctaaactc tgccgtattg tctgcatgaa tatacaaatc
     4141 cccttgataa gagtttatct tgaaatcaat ggcaaaaaca gagagtggaa gaaggcaaaa
     4201 caagcctaac accagtaaga aaaaagtttt tttcatcaac taagccccct ttttatcttt
     4261 cttatcatta tagcattttt tcgtaagtaa aggcttactt atgttgaaaa attacgcatt
     4321 tttcgataaa ataggagaca gttatttttt aatagatcag aataggagaa atcatgagaa
     4381 aaatatactt atctattttc acaagtctct tgctgatgct aggacttgtc aatgttgctc
     4441 aagccgatga atatttacgc atcggtatgg aagcagcata tgctcccttt aactggaccc
     4501 aggatgatga tagcaacgga gctgtcaaaa tcgatgggac caatcagtat gccaacggat
     4561 acgatgttca aatcgccaag aaaatcgcta aggacttagg taaagaacct ttggttgtta
     4621 aaaccaagtg ggaaggtcta gtccctgccc ttacttctgg taagattgac atgattatcg
     4681 caggtatgag tccaactgca gaacgcaaac aagaaattac cttttcgagc agttactata
     4741 ctagcgaacc agttttgctt gtcaaaaaag attctgccta cgcaagtgct aaatctttgg
     4801 atgactttaa cggtgcaaaa atcacttctc aacaaggggt ctacctttat aacttgattg
     4861 cacaaatccc aggtgctaaa aaagaaacag ccatgggaga cttcgctcaa atgcgacaag
     4921 ctcttgaggc tggtgtcatt gatgcttatg tttctgaacg tccagaagca ctgactgctg
     4981 aagctgcgaa ctctaagttc aagatgattc aagtagaacc tggtttcaaa actggggaag
     5041 aagatacagc tatcgctatc gggcttcgta aaaatgacaa tcgtattagc caaatcaatg
     5101 ccagcattga aaccatttca aaagatgacc aagttgcctt gatggatcgt atgatcaagg
     5161 aacaacctgc cgaagctaca acaactgaag agactagcag tagtttcttt agccaagttg
     5221 ctaaaattct ttctgaaaac tggcaacaac tcttgcgtgg tgctggtatc actcttttaa
     5281 tctctatcgt cggaaccatc ataggtctca ttattggact tgccattggt gtcttccgta
     5341 ctgctcctct ctctgaaaac aaagtcattt acggcctaca aaaactagtc ggctgggttc
     5401 tcaatgtcta cattgaaatt ttccgtggta cgccaatgat tgttcaatcg atggttatct
     5461 actatggaac tgcccaagct ttcgggatca accttgaccg tacactggct gctatcttca
     5521 tcgtttcaat caataccggt gcctacatga ctgaaatcgt ccgtggtggt atcctagcag
     5581 ttgacaaggg acaatttgaa gctgcgactg ctcttggtat gacccataac cagaccatgc
     5641 gtaagattgt cctacctcag gtagtccgta acatcctacc tgcaactggt aatgaatttg
     5701 tcatcaatat caaagataca tctgtattga acgttatctc tgttgtcgaa ctttatttct
     5761 caggaaatac cgtggcaaca caaacctatc aatacttcca gacatttaca atcatcgccg
     5821 tgatttactt tgtcctcacc ttcaccgtaa cacgtatcct acgctttatc gagcgcagaa
     5881 tggacatgga tacctacact acaggtgcta accaaatgca aacggaggat ttgaaataat
     5941 gacacaagca atccttgaaa ttaaacacct caaaaaatcc tatggacaaa acgaagtgct
     6001 aaaagacatt tcactcactg tccacaaggg agaggtcatc tctatcatcg gaagctctgg
     6061 aagcggaaaa tcgaccttcc tacgctccat taacctactt gaaacaccaa ctgatggaca
     6121 aatcctttat catggacaaa acgtcctcga aaaaggctat gacctcacgc aataccgtga
     6181 aaagttgggg atggttttcc aatcctttaa cctctttgaa aatctcaatg ttcttgaaaa
     6241 cacaatcgtc gctcagacaa ctgtcctaaa acgcgaacgc acagaagctg aaaagattgc
     6301 caaagaaaac ctggaaaagg tcggcatggg agaacgctac tggcaagcca aaccaaaaca
     6361 actctcaggt ggtcaaaaac aacgtgtggc catcgctcgt gccctctcca tgaatccgga
     6421 cgctattctc tttgatgaac caacatcagc tctcgatcca gaaatggttg gagaagtcct
     6481 caaaatcatg caggacctgg ctcaggaagg cttgaccatg attgtcgtaa cccatgaaat
     6541 ggaatttgcc cgtgatgtct ctcaccgtgt tatctttatg gataagggcg tgatcgctga
     6601 agaaggtaaa ccagaagacc tcttcaccaa tcctaaagaa gaccgaacaa aagagttcct
     6661 tcaacgctat ctcaaataaa aagaaaaggc tgcatcaacc gtgcagtctt tttgctgtcc
     6721 tcaaaatgaa aaggcagatt ctctatctct actacttgaa ggtcaagaat ccgccgttat
     6781 ccaaagatta atcttcaaat ttttcataat ttttttcata gaaatcaatt aggcctaggg
     6841 ctgtttcaaa tgaaatattt tttacttttg cacgaccctg cgccagagca atgatagaca
     6901 tttcacgcgc attcgtttct ttagagatac ggtagcctgt gattttctta tcacgaaccc
     6961 agccaacaac tgattctact ttttcaaagt ttgacttagc catgtttttc tcctattttc
     7021 ttctttataa tatttaattg tatacgtttt tactactttt gtcaataaaa aaaacatata
     7081 ttcaacgaaa ataattagtt cagaattttc ttacttcctt tttaaatccg ataatatata
     7141 ggttttgcta gcctctacac cataaatatt tgctaataaa aatactgtat tattaccctc
     7201 ttaaggtgcg aaattattca agttcttaaa aaatgcttct ctatttccgt aagatagctt
     7261 atttcttcga tttaagaact gaagatgata gttctaacct ttagaaatcc aagccttcac
     7321 tagctcaaaa actcctatct ttcttcctca ataaatcatc tgagagatag gtattcctta
     7381 tgtccttaaa attcatcact cctttggata ttgaggtgct agcctagaag cagacacccg
     7441 attatctaaa ccatccttaa tagagatgac aagacagata agctcagtta attacttata
     7501 tatcttttta atatggtata tttgtcaaca aaaagaaatc aaatcatacc ttatactcaa
     7561 tgaaaatcaa agagcaaact aggaagctag ccgcaagttg ctcaaaacac tgttttgagg
     7621 ttgcagatag agctaacgtg gtttgaagag attttcgaag agtattaaag acagtgtgac
     7681 tatgcttgtc aatagatagg aaatcaaaat gaaggatgga aatctgagcc aaacatcata
     7741 agtgctataa tgaacagaag taagaattgc acgataagtt ttctaaaacc ataggaatcg
     7801 tcccctttct tcatcttcat tatagcacat atacatcagt tgtacaaata atatgatatt
     7861 tttttattag tcctcagaca agcatattat aaagcgtttc attaccattt aagttaatat
     7921 aagctggatc aaaaccttcc attctacgaa tcaaacctgc ataatcatgc ttatctgcta
     7981 aagcgatccc aattaatact gggcctgttc ccttgctagc tcgtttgata tactcaaaac
     8041 gtgtgatatc atcatttggc cccaggatat catttacaaa ctcacgcaaa gctcctggac
     8101 gttgtgggaa attgaccaca aagtaatgtt tgataccatc ataaatcaag gcacgctctt
     8161 ccatttctgg catacggttg atatcattat ttcctccaga aatgatacaa caaatggttt
     8221 tccccttaat atattcagct aaaacctcta aagaggcgat actagccgct ccagcaggtt
     8281 ctgcgactat cccttgctta gagtaaaggt caatcaaggt ttcagaaatc aatccctcat
     8341 cgacacctac caaagtttta atatgttgac gagttgcttc ataggtcaac tgacctacct
     8401 tttgcacagc aatcccatca gcaaatttat caatttcctt gagtttgact ggacctccag
     8461 cctcaaaggc agctttcatg gaacgcgctc cattcgcctc tactccgata acctcaatct
     8521 ctggacttgt ttccttgata taggtagaaa ccccggcaat gagaccgcca ccaccaacag
     8581 gaaccaagac agcatcaaaa tcaatcgatt cttttcgagc ttcttctaaa atctcataag
     8641 caactgttcc ttgacctgct tgaacatgag catcatcaaa aggatcaata aaggtacgat
     8701 tttcagagac tgtaaattct tgagctgctt tggctgaggc atcaaaggta tctccaacta
     8761 gtttaatagt tacaaaatcc ccaccaaaaa agcgaacctg accaatcttt tgttgtggcg
     8821 tagtaatggg cataaagata gtagcaggaa ttttcatttc attacaagta taggctactc
     8881 cctgcgcatg atttcccgca gaagcgcaga ctaccccacg ttcacgttct tccttgctga
     8941 gctgggaaat ggcataatag gcaccacgaa ttttaaagga gcgaacacgc tgggcatttt
     9001 cttttttcaa ataaatctta gcaccatact tctccgataa ataatgatcg taatccagtg
     9061 gagtattcac aaccacaccg ttcaagacct tgtgagcctt gattatatct tttgaactta
     9121 acatataaaa cctctttttc tataaaaaac agtcactaat gactgttttt tagttattca
     9181 tctccgaaaa cttcagtaac actttcatgg tatttatgag ccatacgaat cgaaaactct
     9241 ttaggaagtt cataacgatt tgtggaaatc caatcatata accattctac caaactttct
     9301 tcactatcat tacgatggaa gataaaatag tttaaaattt ctttatattc tacatcattc
     9361 aaatccaacg tgtctacaaa ttgactacga ggaacaaaat tagaatctaa ttttcttagt
     9421 tgatctgtca attctcccaa ttgtaaatcc aactgaaaaa atagtttttg cagttgccta
     9481 tcagtttcat cacatcctgt cttgatagaa aacaaattgg taatattcat atgatttcaa
     9541 cccctaaata agtacatcta atatcccacg aatagctgaa gctaaagttt tcgcagtcca
     9601 gtcatttaaa cccgattctt tcaatccaga tgcaataatt tgctctattt gatataaatc
     9661 gccatctatc gtctcattta ttctgcgaag aggaccttca atataggata aagcttctcc
     9721 gaatctaaca gctgatttag gtcctaatga tttaccaact atatttgtta atgtttttta
     9781 tttctcaaaa tccatttcgc tatataacga gcagatttag tcgcatcagc tctctcaaac
     9841 ggagaatgaa tttcaagacc ttcttctcta gctatttgtg ccaatttgaa gaattgttca
     9901 aaggtcatat gcaacctacc atcttcaaaa ttagcatcat cataaatgtt aattacagca
     9961 ttttcatcat acgaccaatc tgctttattt tggtctgcta gcactattac cgacggtgta
    10021 attacattat acaactagaa ccaataataa cgatgcaatt tttctcataa tctttttcat
    10081 aaaatcatct ccagcgctat atatttctaa ttagttatag attttgaatg catcatcgtc
    10141 gtttttacca acgaatggca ttgctttacg caattctgca ccaacttttt caatttcaag
    10201 gttagctgct tgttcacggt aagcagtcaa ttttggacgt ccagctttat agtcatttac
    10261 aaagtcattt gcaaacttac cattttggat gtctgccaag acagccttca tattttcttt
    10321 aacttgttca gtgattacac gtggacctga tacatagtca ccgtattcag cagtgtttga
    10381 aatagactga cgcattttct tgaatccacc ttcgtagatc aagtcaacga tcaatttcat
    10441 ttcgtgaaga acttcaaagt aagccaattc tggagcgtaa cctgcttctg tcaagacttc
    10501 gaaacctgct tcgataaggg cagtcaaacc accacaaagt acagcttgtt caccaaacaa
    10561 atcttcttca gtttcttctt tgtaagttgt ttcaagaaga cctacacgag ccgctccaac
    10621 acctttacac cagtccatag caatgttttt agcatttcct gttgcatctt ggtatactgc
    10681 ataaagagct ggaacaccaa atccttcttc gtaagtacga cgtaccaagt gtcctggtcc
    10741 tttaggagca cacatgaaga catctacatc cgcaggaact ttgataaatt caaagtggat
    10801 gttgaaacca tgggcaaatc caactgcgtt tccagcttcc aagtttggag cgatttctgc
    10861 ttcgtacaat tcttgttgaa tttcgtctgg cgccaagatc atgataacat cagccaactt
    10921 agtagcttct gctactgtgt aagtatcaaa tccatcttct tttgctttat caaaagattt
    10981 acctggacgt acaccgataa taacgtcacg accggaatca cgcaagtttt gagcatgcgc
    11041 atgcccttgt gaaccataac cgataacggc gattttttta ccgtcaagtg ctgctacttt
    11101 aacatctttt tcatattcca tttgaactgt catagctttt ctctcttttc tattatttat
    11161 tgccttttag gctggtttaa taaatttaag ttggattttt aatcgcgggt aaatccagtt
    11221 gcacccgttc gagcaatatt gcgaataccg tatgggcgaa tgactcgcaa tagggcttcg
    11281 ctcttttctg catttcccgt catctgaatg gtaatcgagc ttggcgctac gtctaccact
    11341 gttgcacgga aaggttgaat aatcgctaaa atctcagctc tcttctcagc tggcgctgac
    11401 atcttaacca aaatcacctc gcgctccaaa tgaggcttgt ctgtaatatc tcgaatgcga
    11461 atcacatcaa tctgacgatt gagctgtttg atgatttgct ccacttcatc atgagaagca
    11521 acatcaataa taatagtgat acgcgataca ttcggatctt ctgttgctcc aacagagatg
    11581 ctttcaatat taacctgacg acgagatagg acacctgtaa agcgattgag tactcctgaa
    11641 cgattttgta gttttgctgt taacattcta cgcatggaac ttcaccccca acatctcatg
    11701 attactctta ccagccggta ccattggtaa cacctgttcc ttacgagaaa tatctacctc
    11761 aattagcata ggaacatcct cagtgatgac ttcaaggtct tgagccaagg tctcaggatt
    11821 gtcaaactta tagtttttaa taccataagc ctgcgccatc aattggaaat caggaagggt
    11881 atcaaagacc gactctgatg ttctgccttc atagaaggat tcctgccact ggcgaaccat
    11941 tccaagtgaa tgattgttca gcataaccac cttgattggc accttgtaaa tattcaaaat
    12001 agccaactcc tggttggtca tttggaaacc accatcccca acaaacaaga ctacttcctt
    12061 atctgggtta gcaattttag caccgattgc tgctggaatt ccaaagccca ttgttcccaa
    12121 accacctgaa gtcactaact gacgctcatt ttggtaggga taatactgag ctgtccacat
    12181 ttggtgttga ccaacgtctg ttaccacaat ggcatctcca ttcgtcaatt caccaattcg
    12241 ttcaataact gcttgcggtt gaaccacacg ctctttcttg tcataagaac gaacacgatt
    12301 cttgtcttta gtgactttct caatccactt ttcagtattg ttgtgaactg ttggttctgc
    12361 tagcaacatt tgcaaggcct tcttagcatc tccaactaca ggaatgtctg cactgataat
    12421 cttgccaatc tcagctgggt caatatcaat gtgggcaacc ttagcattct tagcgaaagt
    12481 cttaggattc cccgtcaaac ggtcatcgaa acgagaacca atactaatca taaagtccgc
    12541 ttccgtcatg gcaatatttg ctgcgaatga cccgtgcatg cctcccattc caagaaagag
    12601 tgggtgactc gttgcaatcg ttccttgtcc caaaagactg gttaccactg gaatttgata
    12661 gcgttctgca aattcattta gttccgtagc agcctcagca taactaattc caccaccagc
    12721 taacaagact ggctttttag ccttggacaa ttgcttcaag attttcttga tttgcatatc
    12781 attcggctca agagtcggct gataacttgg taaattcact tctggtgaat aaatgaagtc
    12841 tgtttctaaa gcagatatgt cttttggtag gtcaattaca actggccctg gacggcctgt
    12901 agttgcgata tggacagctt ccgtaatgat acgcggaata tcagctgtct cacgaacttg
    12961 gtaattgtac ttagtgattg gcatggtaat tcccacgatg tctgcctcct gaaaggcatc
    13021 cttcccaatc cctgctcgcg ccacctgacc tgtaaagacc aaaaggggaa cgctatcgct
    13081 catggcatcc gcaatccctg taatggcatt tgttgctcct ggtccactag tgacgacggc
    13141 aacacccaac tttccagttg atttggcata accttcagct tcatgcaaac aaccttgctc
    13201 atggcgccct agaatgtggc gaatgccttt aaaattatat atcgcatcat aaaaaggcaa
    13261 aaccgcacca ccaggataac caaagatggt atcaactcct aaatcacgaa gtgtttccaa
    13321 aactaggtcc gaccccgtct taggagattc taaactgatt ttctccatta ttcccctttc
    13381 tttcctctta aaaataactt gttactatca taccattttt tcaaaatttt tcaagataaa
    13441 agaagaaatt ttctgaattt tctattttaa cgtttattta tgaatgttat ttttgttttt
    13501 attaaaaaga taccgatttc atttactaaa aaagaaaaaa gaactgattt ctcagtcctt
    13561 cattaatctt attccacact aaataggtat gggtaaacag gttgttgacc ttggtgaatc
    13621 tcgacttcaa cgtcttcgaa ttcttctacg atttcttgag cgatttcatt ggcaagttct
    13681 tcgcttccgt cttcaccgac atagaaggtt acgatttcac tgtcttcatc caacatatgt
    13741 ttcaaggttt cagtcaatgt ttggtgcata tcagggtttg acacaagaat ttttccatcc
    13801 accataccta gattatcgtt ttcatggatt tctaagccat cgatcgttgt atcacgcacg
    13861 gctgttgtga cgcttccgct aacaacatcg ctaagagcag ctgtcatacg ctcttggttt
    13921 tcttcaatgg acttgcttgg atcaaaggca agaagacttg tcataccttg aggaagagtg
    13981 cgagcctcta ccactactgc tggttgctcc aaaacttctg ccgcagattg agctgccatg
    14041 aagatgttct tgttgtttgg caagaagatg atgttacggg cattgacctg ttcaacagcc
    14101 ttgataaagt cttctgttga agggttcatg gtttgaccgc cttcgataac ataatccacg
    14161 ccttgagaac agaagatatc tgctagacct ttaccagcca ccacagcaat caaagcatac
    14221 tctttttctt cagccgactt gataacttga gtagcttctt tctcaacctg tgcttcgtgt
    14281 tggttacgca tattgtcaac ttttaccttg accaagctac catatttgag accttcttgc
    14341 ataacaagtc ctggatcttc tgtatgaaca tggactttga caatttcatc atcgttaaca
    14401 acgaggagag aatccccaag ctcatccaag tagttacgga attcatcgta gtcaaaatct
    14461 ttagcatagg ttggaccttg cttaagagct accatgattt cagtacagta accaaacgtg
    14521 atgtcctcag tcgctacgtg accagctaca gacttatgat gctctacatt gatcatctca
    14581 ctcatgttgg caggagtcgc tacaaagtcc tcagatgcaa tatattcgcc agtaagggct
    14641 gaaaggaaac cttcgtagat gaagaccaat ccttgaccac ctgagtccac aacgccaact
    14701 tctttcaata ctggaagcat gtctggtgtt ttagctagag ctgttttagc accttccaag
    14761 gctgcgcgca tgacttcaac agcgtcatct gtttgctcag cttttttctt agcaccgata
    14821 gcagctccac gagaaactgt taaaatcgtt ccttcaacag gtttcatcac tgccttatag
    14881 gcaacttcca cacctgattg gaaggccaga gccaagtctt gacctgttaa ctcgtcttta
    14941 tccttgatag cttgggaaaa tccacggaaa agctgagacg taatcactcc tgagttccca
    15001 cgcgcaccca tcaaaagccc tttggcaaga atgctcgcta cttctccaac tgtagaagct
    15061 ggcttgtctg caacttcttt agcaccattt tcaatggtca ttcccatatt tgtcccagta
    15121 tctccatctg ggactggaaa gacgtttaat gaattgacat attcagcttg cttattcaag
    15181 cgagttgatg cagcctgcac catttcttga aataagctag tagtaatttt tgacacggtt
    15241 attctcctac aactttgata ttttgaatgt agacatttac agtctgagca gtaattccaa
    15301 gctggttttc caagctaaag gcaacacgct cttgaatgtt ttttgacact tcactaatct
    15361 ttgttccgta gcttaacacg gtatatacat caactgcaat actgccatct tcggctgcct
    15421 ttacgacgac acctttagaa taattttcct tacctagcag ggcttggaaa ttatctttga
    15481 gggcattttt actagccata ccgaccacac caaaaatctc agttgctgct ccacctacga
    15541 cggttgcaat cacttcatct gttagttcga tttgaccatc ttttgtatta atttttacag
    15601 tcatcctttt tacctcaact agttgatact ctattttatc atatttcagc ccaagtgtaa
    15661 aagcagaatg atgtatcagc ggatatttac tctatttttc aaacgatgtt atacccacaa
    15721 taaaagaaaa aagaccctaa ggtctccttt gcttttatta ttaaacgcgt tcaactttac
    15781 ctgatttcaa agcacgagct gaagcccaaa cttttttagg tttaccatcg ataagaacag
    15841 taactttttg aaggtttggt tttacggcac gttttgtttg gttcatcgcg tgtgaacggt
    15901 tgtttcctga tacagtctta cgacctgtaa agtaacatac tttagccatt gtgttttcct
    15961 cctattagat ctaatatagc ggatgtgcta gcaccacata ccgtactatg ttatcacact
    16021 ttcttgtttt ttgcaaggga attggaagat tttttatttg tgtcttaaat caggtcttgc
    16081 gtgacatttt ctgctctcca catgccattg ttgattaaca gaacaccaga attaaaatta
    16141 tgtgtataaa aatcatctct aactgcagct aagggtatag ccgtcaagtc caaatcccac
    16201 agctcatcta tcgattttct tacaacaata tctgaatcca aatacagtac acgagactcg
    16261 cttacatact ttggaataaa atacctaaaa aaagccgcat atgaaagtcc ctcaaagggg
    16321 agacgataac ctttcagaat actactgtca atctgaacat tcacaatctc actattcaaa
    16381 gtctctagtc ttttttccat caattggaac cattctcgcg gaaggtcatc attaaaaaca
    16441 taaaacttaa gattataatg atgaacacaa agagatttta ttgttgtttc aactttatcc
    16501 atataagcat tatctgcacc taagacaatc gcttttttct cttctttcac tctttatctt
    16561 atttcttttt attcccatca tattattccc atcatatgtt tctacgtaac cattattttc
    16621 gcctattcgt tcgtaaaacc ataccagtgg agattttaga tgaagtccca ttacggttta
    16681 cattttttac attacgacac ggagttttac aaatcgattt catttgccaa acgtagttag
    16741 tgaggcagtt agctagttcg ccaaatagcg actagcgtcc aacaatttgg aactttagtt
    16801 ccaattgttg gtactgagtc acatcttctc ctctaactct acgtctggat acttgtccgc
    16861 aaaccagcgg agggcaaagt cattttcaaa gagaaagact ggttggtcaa aacggtcttt
    16921 ggctaagata ttgcgacttg acgacatccg ttcatccaag tcctcaggct tgatccaacg
    16981 aacggtcttt ttacccattg ggttcataac tacttccgca ttgtactcgc tttccatgcg
    17041 gtgtttaaag acttcaaact ggagttgacc tacagcgcct agcatgtact cacctgtttg
    17101 gtaattctta taaagctgaa cggctccttc ttgcaccaat tgctcaatcc ccttgtggaa
    17161 ggatttttgc ttcataacat tcttagcaga aactttcatg aaaatttcag gagtaaaggt
    17221 tggcagtggt tcaaattcaa acttgttttt tccaaccgtc aaggtatccc caacctgata
    17281 agtaccggta tcgtaaaccc cgataatatc acctgccacg gcattggtca cattctcacg
    17341 actctccgcc ataaactggg taacattaga tagtttggca cccttaccag tacgagggag
    17401 attgacactc atgccacgct caaattcgcc tgatacgata cggacaaagg caatacggtc
    17461 acggtgacga ggatccatgt tggcttggat tttaaagaca aagcctgaga aatccttgtc
    17521 ataaggatcc acaatttcac cgtctgtttt cttgtgacca tgtggttctg gagcaaactt
    17581 gaggaagatt tcaaggaagg tctgcacacc aaagtttgtc agggctgaac cgaaaaagac
    17641 aggcgtcaat tctccagcca gaatagcttc ctctgaaaac tcattcccag cttcatttaa
    17701 aagctcaatg tcatccttga cttgctcgta gaaaggattg ctaccaaaaa gtttgtctcc
    17761 atcttctagg ctagcaaaac gctcatcccc tttgtaaagc tctaaacgtt ggttatagag
    17821 gtcatacaag ccctcaaagg ctttccccat cccgataggc cagttcatag ggtagctagc
    17881 aatgcccaag atttcttcca attcttgcaa gagatccaaa ggctcacgac cgtcacgatc
    17941 caacttgttc ataaaggtaa agactggaat gccacgatgt ttcacaacct caaacaattt
    18001 ctttgtttga gcctcgatcc ccttggcaga gtccacgacc atgaccgcag catccaccgc
    18061 catcaaggta cgataggtat cttctgagaa gtcctcgtgc cctggcgtgt ctaagatatt
    18121 cacgcgcttg ccgtcgtagt caaattgcat aacagatgaa gtaacagaaa tcccacgttg
    18181 cttctcgata tccatccagt cagatttagc aaaagtccct gttttcttcc cttttaccgt
    18241 accagcatca cgaatctcac ccccaaagta gagtaactgc tcagtgatgg ttgttttccc
    18301 cgcgtccggg tgggagataa tggcaaaggt acgacgtttc ttaatttctt cttgaatatt
    18361 cataagttct ctttctttga ttctctattt ttcttgtttc aatagctgag aatgattttt
    18421 acattggatt ttaccattcc tttcgacact ccattatatc ggattttagc atttttttca
    18481 atttctattt cttttcactt ccccctccct tatttatagg aaaatatggt aaaatagaac
    18541 agactaaaaa tcatcatttc acgaaaggat gcaagatgaa aattacgcaa gaagaggtaa
    18601 cacacgttgc caatctttca aaattaagat tctctgaaaa agaaactgct gcctttgcga
    18661 ccaccttgtc taagattgtt gacatggttg aattgctggg cgaagttgac acaactggtg
    18721 tcgcacctac tacgactatg gctgaccgca agactgtact ccgccctgat gtggccgaag
    18781 aaggaacaga ccgtgatcgc ttgtttaaaa acgtacctga acaagacaac tactatatca
    18841 aggtgccagc tatcctagac gatggaggag atgcctaatg acttttaaca ataaaactat
    18901 tgaagagttg cacaatctcc ttgtctctaa ggaaatttct gcaacagaat tgacccaagc
    18961 aacacttgaa aatatcaagt ctcgtgagga agccctcaat tcatttgtca ccatcgctga
    19021 ggagcaagct cttgttcaag ctaaagccat tgatgaagct ggaattgatg ctgacaatgt
    19081 cctttcagga attccacttg ctgttaagga taacatctct acagacggta ttctcacaac
    19141 tgctgcctca aaaatgctct acaactatga gccaatcttt gatgcgacag ctgttgccaa
    19201 tgcaaaaacc aaaggcatga ttgtcgttgg aaagaccaac atggacgaat ttgctatggg
    19261 tggttcaggt gaaacttcac actacggagc aactaaaaac gcttgggacc acagcaaggt
    19321 tcctggtggg tcatcaagtg gttctgccgc agctgtagcc tcaggacaag ttcgcttgtc
    19381 acttggttct gatactggtg gttccatccg ccaacctgct gccttcaacg gaatcgttgg
    19441 tctcaaacca acctacggaa cagtttcacg tttcggtctc attgcctttg gtagctcatt
    19501 agaccagatt ggaccttttg ctcctactgt taaggaaaat gccctcttgc tcaacgctat
    19561 tgccagcgaa gatgctaaag actctacttc tgctcctgtc cgcatcgccg actttacttc
    19621 aaaaatcggc caagacatca agggtatgaa aatcgctttg cctaaggaat acctcggtga
    19681 aggaattaac ccagaggtta aggaaaccat tctaaatgcc gctaaacact ttgaaaaatt
    19741 gggtgctatt gtcgaagaag tcagccttcc tcactctaaa tacggagttg ccgtatacta
    19801 catcatcgct tcatcagaag cttcatcaaa cttgcaacgc ttcgacggta tccgttacgg
    19861 ctatcgcgca gaagatgcaa ccaaccttga tgaaatctat gtaaacagcc gaagccaagg
    19921 ttttggtgaa gaagtgaagc gccgtatcat gctgggtact ttcagtcttt catcaggtta
    19981 ctacgatgcc tactataaga aggctggaca ggtccgtaca cttatcattc aagatttcga
    20041 aaaagtcttc gcggattacg atttgatttt gggtccaact gctccaagtg ttgcctatga
    20101 cttggattct ctcaaccatg acccagttgc catgtactta gccgacctat tgaccatacc
    20161 tgtaaacttg gcaggactgc ctggaatttc gattcctgct ggattctctc aaggtctacc
    20221 tgtcggactc caattgattg gtcccaagta ctctgaggaa accatttacc aagctgctgc
    20281 tgcttttgaa gcaacaacag actaccacaa acaacaaccc gtgatttttg gaggtgacaa
    20341 ctaatgaact ttgaaacagt catcggactt gaagtccacg tagagctcaa caccaattca
    20401 aaaatcttct cacctacttc tgcccacttt ggaaatgacc aaaatgccaa cactaacgtg
    20461 attgactggt ctttcccagg agttctacca gttctcaata aaggggttgt tgatgccggt
    20521 atcaaggctg ctcttgccct caacatggac atccacaaaa agatgcactt tgaccgcaag
    20581 aactacttct atcctgataa ccccaaagcc taccaaattt ctcaatttga tgaaccaatc
    20641 ggatataatg gctggattga agtcaaacta gaagacggta cgaccaagaa aatcggtatc
    20701 gaacgtgccc acctagagga agacgctggt aaaaacaccc atggtacaga tggctactct
    20761 tatgttgacc tcaaccgcca aggggttccc ttgattgaga ttgtatctga ggcagatatg
    20821 cgttctcctg aagaagccta tgcttatctg acagccctca aggaagttat ccagtacgct
    20881 ggcatttctg acgttaagat ggaggaaggt tcgatgcgtg tggatgccaa catctccctt
    20941 cgtccttatg gtcaagagaa attcggtacc aagactgaat tgaagaacct caactccttc
    21001 tcaaacgttc gcaaggggct tgaatacgaa atccaacgtc aagctgaaat acttcgctca
    21061 ggtggtcaaa ttcgccaaga aacacgccgt tacgatgaag ctaacaaaac aaccatcctc
    21121 atgcgtgtca aggaaggggc tgcagactac cgctacttcc cagaaccaga cctacccctc
    21181 tttgaaattt ctgacgagtg gattgaggaa atgcggactg agttgccaga gtttccaaaa
    21241 gaacgtcgtg cgcgttatgt atctgacctt ggtttatcag actacgatgc taatcagttg
    21301 actgctaata aagtcacttc tgacttcttt gaaaaagctg ttgccctagg tggtgatgcc
    21361 aaacaagtct ctaactggct ccaaggggaa gtcgctcagt tcttgaatgc tgaaggtaaa
    21421 acactggaac aaatcgaatt gacaccagaa aacttggttg aaatgattac catcatcgaa
    21481 gacggtacta tttcatctaa gattgccaag aaagtctttg tccatctagc taaaaatggc
    21541 ggtggcgcgc gtgaatacgt ggaaaaagca ggtatggttc aaatttcaga tccagctatc
    21601 ttgatcccaa tcatccacca agtctttgcc gataacgaag ctgctgttgc cgacttcaag
    21661 tcaggcaaac gtaacgccga caaggccttt acaggattcc ttatgaaggc aaccaaaggc
    21721 caagccaacc cacaagttgc ccttaaacta cttgcacagg aattggcgaa gttgaaagaa
    21781 aactagacag aacaaaacca gccctaaggt tggttttttc ttgacaaata gaaagaaaac
    21841 gtttacaata ttgcgtgtaa agtttccaaa caagaaaact aaaaatcgca acaataagga
    21901 gttatttata tggctacaat gaaggcagct cgctggcatg cagcgaaaga tgttcgtatt
    21961 caagaaatag aagttcctga agtacttccg caccaagtaa aagttgcagt taagttcaca
    22021 ggaatttgtg gtactgacct ccatgaattt ttagatggac ctatctttat cccaacagat
    22081 gagcacgtct attctggtca aaaagcaccg gtaacactgg gacatgaatt ttctggtgaa
    22141 atcatagaag tcggaagcga tgttacccgt gttaaagttg gtgatcgtgt tgctgtggaa
    22201 ccaattctag ctaaaaataa cttagttggt gattataatt tggatccaaa ccttaatttt
    22261 gtcggtttgg ctgcagacgg tggatttgcc aaatattgtg ttttagacgg tgacttagta
    22321 catgtcattc cagatagctt gagctatgaa caagctgctc ttactgaacc cgctgctgtt
    22381 gcagtctatg ctgttcgtca atcttctttg aaggctggcg atacagctgt tgtctttggt
    22441 ttaggcccga ttggtctatt aattgtagaa gctcttcgtg cagctggtgc ttctaagatt
    22501 tatgctgttg aactatcacc tgaacgtcaa gcaaaagctg aagagttagg agctatcgtt
    22561 gtccgtccgg aagaaggtga aacagctgtt gaagctattc atcgtttaac aaacggtggt
    22621 gtagatgttt cttatgaagt aacgggtgtg ccagtagttt taggacaagc cttagctgcc
    22681 gtacataaag caggtgagtg catggtggtc tctatctggg aacgagaagc aaatattaat
    22741 ccgaatgaat ttgcaatcca agaaaagaca ctaaaaggaa tcatcgctta tcgtcatatc
    22801 ttccctaaag tattagaatt gatggaacaa ggctacttct ctgctgaaaa attagttact
    22861 aagaaaatta aattggaaaa tatcgtcgaa gaaggcttta tcgaattaac tcaagataag
    22921 tcacaaatta aaattttggt agaaccagaa taaaaaatca atctttttaa gacaatacta
    22981 acaggtcgga gtaaacttac ttcggccttt tgaaatataa tactcttcga aaatctcttc
    23041 aaaccacgtc agcgtcacat taccgtatat atggttactg acttcgtcag ttctatccac
    23101 aacctcaaaa cagtgttttg agcagcctgc ggctagcttc ctagtttgct ctttgatttc
    23161 cattgagtat gagaagaaat atagtggata ctctttaaca ttaaccactc cacctgacta
    23221 gccaatattc tttttcgctc ctaccaactc ccaataacta ttttggcttt atttccagag
    23281 tattttatgg taaaatgaag agtaataata tttgttaaag aggtaaaaac atgattgaag
    23341 caagtaaatt aaaagctggt atgacctttg aaacagctga cggcaaattg attcgcgttt
    23401 tggaagctag tcaccacaaa ccaggtaaag gaaacacgat catgcgtatg aaattgcgtg
    23461 atgtccgtac tggttctaca tttgacacaa gctaccgtcc agaggaaaaa tttgaacaag
    23521 ctattatcga gactgtccca gctcaatact tgtacaaaat ggatgacaca gcatacttca
    23581 tgaatacaga aacttacgac cagtacgaaa tccctgtagt caatgttgaa aacgaattgc
    23641 tttacatcct tgaaaactct gatgtgaaaa tccaattcta cggaactgaa gtgatcggtg
    23701 tcaccgttcc tactactgtt gagttgacag ttgctgaaac tcaaccatct atcaaaggtg
    23761 ctactgttac aggttctggt aaaccagcaa cgatggaaac tggacttgtc gtaaacgttc
    23821 cagacttcat cgaagcagga caaaaactcg ttatcaacac tgcagaagga acttacgttt
    23881 ctcgtgccta atctctagaa agaggtcatt ctatgggaat tgaagaacaa cttggcgaaa
    23941 tcgttatcgc cccacgtgta cttgaaaaaa tcattgctat cgctactgca aaggtagagg
    24001 gtgttcactc tttttcaaac agatcagtgt ctgataccct ttcaaaactt tcactcggcc
    24061 gtggcattta tcttaaaaac gtggacgaag aactcacagc agatatctat ctctaccttg
    24121 agtacggagt aaaagttcct aaggtagcgg ttgctatcca gaaagctgtc aaagatgccg
    24181 tccgtaatat ggctgatgta gaactcgctg ctatcaatat tcacgttgca ggtatcgtcc
    24241 cagataaaac accaaaacca gaattgaaag atctatttga cgaggacttc ctcaatgact
    24301 agtccactat tagaatctag acgccaactc cgtaaatgcg cttttcaagc tctcatgagc
    24361 cttgagttcg gtacggatgt cgaaactgct tgtcgtttcg cctatactca tgatcgtgaa
    24421 gatacggatg tacaacttcc agcctttttg atagacctcg tttctggtgt tcaagctaaa
    24481 aaggaagaac tagataagca aatcactcag catttaaaag caggttggac cattgaacgc
    24541 ttaacgctcg tggagagaaa cctccttcgc ttgggagtct ttgaaatcac ttcatttgac
    24601 actcctcagc tggttgctgt taatgaagct atcgagcttg caaaggactt ctccgatcaa
    24661 aaatctgccc gttttatcaa tggactgctc agccagtttg taacagaaga acaataaaaa
    24721 gaaaaagtgt ttgatagata tcaaacactt ttttctttgc ctcccactat ctaaaaaaat
    24781 gataatagat ataattgtaa acaaaaatcc agataggttt tgcatgattg agaaagttaa
    24841 aaaaactatg gcagagaatc gttaatctca gattgtcggt agaacgataa acaagggcaa
    24901 aaaagaaacc aatcagacta taatataata aactaattgg atctctgtga gatagtatca
    24961 aatggctaat cccaaagatg atagcagata ggataacatc caaatagtac ttggactagg
    25021 gaaagaaggt attcataaaa taccctctat caagagtctc ctcaaaaaca ggaccgatga
    25081 ttacaggcag gacaaaagat aagatagtcg ataaaaaggt tggttgtcca tttgaaaaaa
    25141 gcacggtaaa atactcatca tgaatattcc tatgattaat caaatgagca tagcgtgccc
    25201 aaaaattacc gagaatctga taaaccacat aagttgcaaa taagtagaag acaaatgacc
    25261 agttccagct ctttttctca aagataaaga gcatcttttt cttttttaac ctccaaatta
    25321 atagaaggaa acttcccact aatcccattg ttaaaataag agaatagaca tcagctccta
    25381 accctaaaat gatcgtcaca tacaatccaa ttgtttgtgg taaataggta gatagtaaaa
    25441 taataagcaa aaatattcca aattgtctta gtttttttgt gtttctcatc gtactttttt
    25501 gaaagattac cctgctcgga agccgtactt ccaagcatct atataagaat taagtgcccc
    25561 ttgcctcata tagggagcaa attctctata atataaccat ctactatatc catcttccca
    25621 aacagcaaga ccacctgaag tttgctccaa gtcctcagtt gaaagaactg taaatgtatt
    25681 tgtacctgtc attgcaagta ccttcttaaa atagattgtt gtaggctcac atttatagta
    25741 tatttctttt tttgtctatt ttatagccca tctcctcaac tggcaatttt tcgacctgaa
    25801 ttacattttt ccataaaaaa tgagaccttt ctagtctcat ttagtcattc ttagtatttt
    25861 ctaaatcgtt gatagcgttc ttccagcaac tcttctagcg gtttttgtga aagtctagcc
    25921 agctctgttt ggagttcttt tttgacactc ttaatcagtt ctttactaga aagtcctatt
    25981 tcagaaatca ccttatctac cacgtccatt tctaacagtt catgcgaagt gattttcatc
    26041 agttctgctg cttccatagc gcgagtaccg tccttccata aaatggaagc aaagccttct
    26101 ggactgagaa tggcatagat agaattttcc agcatccaga cacggtccgc gacagctaga
    26161 gccagagccc cgcctgaacc accttcaccg ataataatgg cgataatagg aactttcagg
    26221 tcactcattt ccatgagatt gcgagcgata gcttcccctt gaccacgttc ttccgctccg
    26281 acaccaggat aagcacctgc tgtattgata aaggtcacaa ctggacggcc aaatttctca
    26341 gcctgtttca tcaaccgcag tgcctttcgg tagccttctg gatgtggttg gccaaaattc
    26401 cgtttgaggt tgtcttgcaa actcttgcct ttttggatac caaccactgt tacagcttga
    26461 tctccaagcc aaccaatacc accaacaact gcaccatcat cacgaaaaga acggtcacca
    26521 tgtaattgga taaattcatc aaaaatgcct gtcgcaaagt ccaaggttgt caagcgactc
    26581 tgctcacgcg cttctctgac tatttttgca atattcatct aggactccct ccatgcaatc
    26641 tgactaggct agcaatcgta tctggtaagt ctcttctttt gacaatagca tccacaaagc
    26701 catgttctaa taggaattct gccttttgga aatcctcagg caagctttca cgaaccgtat
    26761 tttcaatcac acgacgccca gcaaaaccaa ccaagctctg tggttcagcc agaatgatat
    26821 cgccttccat agcgaaagaa gctgtcacac caccagtcgt tggatctgtc aaaatggtca
    26881 ggtaaaagag accaacattt gaatggcgtt taaccgccgc agagatctta gccatctgca
    26941 tgagactcat gattccttcc tgcatacggg ctccaccaga ggctgtgaat aggacaactg
    27001 gcaatttttc gacagtcgca tactcaaaca aacgagtgat tttttcacct acaaccgtac
    27061 ccatagaagc catgataaag ttagaatcca taatcccaag agccacagtc tgacctttaa
    27121 taagagcagt tcctgtcaca acggcttcat gcagacctgt tttttcacgc atagatgcca
    27181 gtttcttttg gtaaccaggg aaatgcaagg gatccttgct ttcaatccct gtaaacaatt
    27241 ctttgaaggt tcccatatca atcgtcaaag ccaagcgttc ttgggcagaa atacgaaagg
    27301 tatagctaca gtgcggacag atacgttcac ttcccagatc cttctgatag atggtatgct
    27361 tacagcctgg acactgggaa aataattcat ctggaacctc tggcttagct tgaggttttt
    27421 ccctaaccga acgattggga ttgattcgaa tatacttatc ttttttacta aatagagcca
    27481 ttgattcccc ttttcggttt aaactcttaa agtcatttta ttctttttct tgatatttag
    27541 gtaagaaggt ttccatcaag aaggaagtat cataatcccc agcaatgaca ttgcgatctg
    27601 aaatgaggtc aagctggaaa tctgcattgg tctgcactcc ttcaatctct aattcataga
    27661 gggcacgttg cattttcatc aaggcgtcaa aacgattttc gccgtgtact atgattttgg
    27721 caatcatact atcataataa ggcggaatgg tataacctgg ataaactgct gaatccacgc
    27781 gcaaaccaac tccaccactt ggcagataga gattagtaat cttacctgga cttggagcaa
    27841 agttaaaggc tgggttttct gcattgatac gacactcgat ggcatgacca cgtaggacaa
    27901 tatcttcttg cttaacagac aaaggctgac ctgccgcaat gcaaatctgt tccttaacga
    27961 tatcaacacc tgaaacaaac tctgttactg gatgttctac ctgaacacga gtattcatct
    28021 ccatgaaata gaaattgcta cttgcttcat caagaagaaa ttcaatggtt cctgcattct
    28081 catagccaac aaactctgcc gctcgaacag cagcagcacc tatttcatga cgcagcgttt
    28141 ttccgattgc aatcgaggga ctttcttcca aaaccttttg gttattcctt tgaagagaac
    28201 aatcccgttc acccaagtga atcacatgtc catgctcatc acctaggatt tgaacctcaa
    28261 tgtgccgagc tggatagata acccgttcta tgtacatggc accattgcca taattggcct
    28321 tggcctcact agaggcagtt tcaaaggcag aaacgaggtc atctggtttt tcaaccttac
    28381 gaatcccttt accacctcca cctgctgaag ccttgagcat aacaggatag ccaatttttt
    28441 cagcaacaat caaagcttct tcagagttat gcacttctcc atctgaacct ggtataacag
    28501 gcacacctgc tttaatcatc tgagcacgcg cattgatctt atcccccatc atatccataa
    28561 catgaccaga tggaccgata aacttgatac ctacttcttc acacatggtc gcaaatttgg
    28621 aattttcact gagaaatcca aaaccagggt gaatagcttc tgcctcagtc aagactgcag
    28681 ctgatagaac tgcattaata ttgagataag actctgttgc cttgccagga ccaatacaaa
    28741 ctgcttcatc tgccaaaagc gtatgaagag cttccttatc agcagttgaa taaaccgcta
    28801 ccgtcgcaat ccccaattca cgtgccgcac ggataatacg aaccgcaatt tcaccacgat
    28861 tggcaattaa aatttttcga aacatggaga acctccttag ttcccaattg caaaagtaag
    28921 gataccactg gctgcaagct tgccatccac ttcagccttt gcttcaacca cagctatggt
    28981 gccacgacgt tttacaaaag tcgctgtcat aaccaattgg tcgcctggta caacttgctt
    29041 cttgaactta accttgtcca taccagcgta aaagaccagt tttcctttat tttcaggttt
    29101 tgataactcc aacacaccag cagtttgcgc caaggcttcc ataatcagaa cacctggcat
    29161 aactgggtat tgaggaaagt ggccgttaaa gaaaggttcg ttaatggtca catttttgat
    29221 agcaacaatg gtatcctcgc tcacttccaa gacacggtcc actagaagca taggataacg
    29281 gtggggaaga gcttctttga ttccttgaat atcgatcatt tgatacgtac caatccttta
    29341 ccaaactcaa ccatttcttc gttagagacg agaatttccg ttaccacacc atccttagga
    29401 gctgggattt cattcatgac tttcatggct tcgataatta ccaatgtttg accttttttg
    29461 acactatcac caactgtaac gaaggcaggt ttatctggtc cagcagccaa gtaaaccact
    29521 ccaacaagtg gactctctac aagatttccc tcactagcca cacttgcttc agctggagct
    29581 ggaacttctt ctgctacagt ctctgctgga gcagatgtag gagctactgg attcggtgtt
    29641 gctagaacgg gtgctggagc gacttgagtt gcaacttcag gcacaggtct cgcttcattc
    29701 ttgctaaact gcaactcatc cgtcccattt ttataagaaa attctctcaa acttgactgg
    29761 tcaaattgag tcatcaagtc tttaatatcg tttaaattca tacttatcta ttctcccaac
    29821 gtttgaaagc aagaactgca ttgtggcctc caaaaccaaa agtatttgaa atagcgtatg
    29881 gaatttcttt ctccaagcct tgtccataaa cgacattagc ttcgatataa tctgatactt
    29941 cacttgtccc agctgtcatt ggtacaaagt tatgacgcat agcttcgatg gtgacgatag
    30001 cttctactgc acccgcagcc cccagcaaat gtcctgtaaa agacttggtt gatgatacag
    30061 gtacttcctt accaagaaca gctacgatag caccactttc tcctttttca ttggcaggag
    30121 ttgacgttcc gtgagcattg acataggcta cttgctctgg agaaatctca gcttcttcca
    30181 aggctagttt gatggccttg atagctccct gaccttctgg atgtggagaa gtcatgtggt
    30241 aggcatcaca agtatttccg taaccaacca cttcagccag gatagtagct ccacgttttt
    30301 cagcgtgttc aagactttct agaaccaaca tccctgaacc ttcacccata acaaacccat
    30361 tgcgatcctt atcaaatggg atcgaagcac gagttggatc ctctgtagta gagagagctg
    30421 ttaaggcttg gaaaccagcg atggcaaaag gtgtgataga agcttctgtt cctcccacca
    30481 acatcacatc ttggaaacca aacttaatgg agcggaaggc atccccaatc gcatcatttg
    30541 atgaagagca ggcagtattg atagatttac aaacaccgtt tgcaccaaaa cgcatggcta
    30601 cattcccaga agccatattt ggtaaagctt ttggaagagt cattggtttg acacgtttgg
    30661 gtcctttttc atgaaggcga agtacctgat cttcaatttc cttgattcca ccaataccag
    30721 atgcaacgat aacaccaaaa cgatccctat taagagcctc tacatcaaga ttggcatgat
    30781 ttacagcctc ttgggctgca tacaaggcat ataaagaata gttatcaaaa cggttggtat
    30841 ctttttttac aaagtattta tcgaacggaa aatcttggat ttctgccgca ttatgcacat
    30901 caaagtcact atgatcaaat tttgtaatgc caccaatgcc gattttccca gttgctaaac
    30961 tattccaaaa ttcttctggt gtatttccga ttggagatgt tactccataa cctgttacca
    31021 ctactcgatt tagtttcatt cttttcacct ctagctttcg ctacatactt aagccaccat
    31081 caatggcaac cacttgacca gttagataat cttggcctgc taaaaatact gtcaaatctg
    31141 caacctgctc tgcctgccca aattctttca tcggaatctg agctagtgta gcttccttaa
    31201 tcttatctga taagatagct gtcatatcag actcaatcat tcctggagca atcacattga
    31261 ctcgtatatt ccgactagcg acctcgcgtg ccacagactt ggtaaagcca atcaagccag
    31321 ccttagaagc agcatagtta gcttgaccaa tattccccat caaaccaaca acactagaca
    31381 tattaatgat agcaccttct ctggctttca tcatcggttt caagactgat tgtgtcatat
    31441 taaaggcacc agtcagattg accttgagca ctttttcaaa atctgcttct gtcatcttga
    31501 gcataagagt atcttgggta atccctgcat tgttgaccaa aacatctact gaacccagtt
    31561 ctgcaatagc ttgatcaatc atacgcttag cgtctgcaaa atctgataca tctcctgaaa
    31621 tgggaaccac cttgatacca tagtttgaaa actcagcgag caattcttct gagattgccc
    31681 cacgactgtt taagacaatg ttggctcctg cttgagcaaa cttgtgggcg atggcaagac
    31741 caattccacg actcgaacct gtaataaaga tatttttatg ttctagtttc atttttttcc
    31801 tttcaaaact tctacttatt ttagtctatt tttctaaaag tgctactaaa ctcgcttgat
    31861 cttccacatg agctaagtga gcagtttgat caattttttt aacaaaacct gacaagactt
    31921 tccccggtcc aatctcgata aagttgctta tgcctgcttc ttgcatgacc ccaatacttt
    31981 catagaaacg aacgggttcc ttgacctgac gcgtcaagag ctgagcaatg tcctcttttt
    32041 gcatcacagc agcttctgta ttgccgacta ggggacaagt aaaatctgaa aaacttacct
    32101 gagctagagt ttcagctagt ttctggctag caggctcaag gagagcggtg tgaaagggac
    32161 ctgacacctt aagaggaatc aagcgtttgg cacctgcttc ttgcaaaagt tcaaccgctc
    32221 gatcaactgc aaccacttct ccagcaatga cgatttgtgc aggtgtgtta tagttggctg
    32281 gagtaaccac tccaagttca gaagcttttt gacaggcttc ttcaatgacc tctactggcg
    32341 tattgagaac tgctaccatc ttgccagagt cagcaggagc cgcttcttcc atataggctc
    32401 cacgcttagc taccaaggca accgcatctt caaaatccaa ggcgccgctt gccaccaagg
    32461 cagagtattc tccaagagac aaaccagcaa ccatatcagg ctgatagccc ttttcttgca
    32521 ataaacggta gatagcaacc gaagtcgcta gaatggctgg ttgcgtatag cgggtctgat
    32581 tgagtttgtc ttcttccgta tcgatgagat aacgtaaatc ataaccgagc acctgactcg
    32641 ctcgatcaat cgtttctttg acaatcggat actgatcata gaaatcccgt cccatcccta
    32701 gatactgggc accttgacca gcaaataaaa aggctgtttt agtcatttct tacaactcct
    32761 gcccagcgag aggcttcttc ttgaattttc ttagcggctc cgtaatacaa atcttttagg
    32821 atttcttcag ctgtttcttc tttagaaaca agccctgcga tttgacctgc catgacagag
    32881 ccaccatcca catcaccgtg aacaactgct ttggctaggg cacctgctcc catttgttca
    32941 aagatttcta aatcaggatc ttcctgctta aaggcatctt tttcagccag ttcaaaatct
    33001 ctagtcaact gatttttaat agcacgaaca gcatgaccaa agtgctgagc tgaaatcgta
    33061 gtatcaatat cccttgcttt taaaattttc tccttgtagt ttggatgggc attcgactct
    33121 tttgcaacta caaaccgtgt ccccacctgt acagcctctg cacctagcat aaagccagcc
    33181 gcagcacctt caccatccgc aattcctcct gcagcaataa caggaataga tatagctgtg
    33241 gctacctgtc gcaccaaggt catggttgtt aatttaccga tatgcccccc agcttccatt
    33301 ccttctgcaa taacagcgtc tgcaccgatt ttttccatgc gtttagctaa agcgacacta
    33361 ggaacaacag gaataacgat tatcccagct tcatggaaac gttccatata cttgcttgga
    33421 tttcctgctc ctgttgtgac aactttaaca ccttcttcaa taacgagatc cacgatatct
    33481 tccacaaagg gagataagag catgatgttg accccaaagg gtttatcagt caatgatttg
    33541 attttatcaa tattggcctt gacaacttct ttcggggcat ttcccccacc gataattcct
    33601 aatcctccag ccttggaaac agcccctgcc aaatcaccat cagcaaccca ggccatccct
    33661 ccttggaaaa taggatagtc aatcttcaat aattctgtaa tacgcgtttt catagtgcct
    33721 ccaaccttcc ttgcttacgt aatagttcga tttcaccata atttgacagt caaactatta
    33781 cctaaacaag agggagtggg tttctcccta ctccttctac taatattctg cttattttgc
    33841 ttgctcttca acgtaagcaa ccaagtcacc aactgttttc aagtcatttt ctgcttcgat
    33901 ttggatatca aaagcatctt cgatttctga gattacttgg aacaagtcca atgaatctgc
    33961 gtccaaatca tcaaaagttg attcaagtgt tacttctgat gcgtcttttc caagttcttc
    34021 aacgataatt tcttgtactt tttcaaatac tgccatgata ggactccttt aaaataaata
    34081 gtttttttat aacaatgtgt tcaccacatg attacctaaa ttgtaagaat gagcgtgccc
    34141 caggtcaagc ctccaccgaa gcctgataga agaacagtct ggctaccatc taaagggatg
    34201 agaccttgtt ctacacactc tgaaagtaaa atcgggatac tggctgcact ggtattgcca
    34261 tattccatca tattggctgg aagtttggct cggtcaacac caatttttct agccatctta
    34321 tccaaaatac ggtcattggc ttgatgaagt agcagataat ccaagtctgt cacctctata
    34381 ggagattcat caatagtctg cttgatagac ttggctacat ctcgaatggc aaaatcaaag
    34441 actgtgcgtc catccatctt caaaaacgaa tctgcacttt cttgatctga aaatggagaa
    34501 tgcaaacctg aatgcccata agttaaacac tcgctgcgac ttccatcgct attgagactc
    34561 tcagctaaga aatgctcttg ctcgctagct tctaacaaga caccaccagc accatctcca
    34621 aacaacacag ctgttgatcg atccgaccaa tcgactgcct tagagagggt ttcactacca
    34681 atcaccaagc ctttttgaaa gcgaccagaa gcgataaact tttcagcagt tgaaagagca
    34741 aatacaaatc cactgcaagc cgcggttaag tcaaaagcaa aggctttatt agcgccaata
    34801 ttagcttgaa cacgagcagc tgtagagggc atcatcgaat ctggagtaat ggtagctagg
    34861 atgataaaat ccagttcttt tcctgttatt ccagcttttg ccatcagttt cttagcaacc
    34921 tctgtagcca aatcactggt agattctgtt cttgaaatat gcctttgtcg tattcccgtt
    34981 cgacttgaaa tccactcatc attggtatcc ataatctgag ccaagtcgtg atttgtaacc
    35041 acttgctctg gcacataatg agcaacctga cttatttttg caaaagccat tatttcaaat
    35101 cctccaaaaa ttggtaaaga ttagtcaagc ctttacccat gacagcaatt tcttcctcgc
    35161 tcatgccatc aataattttt tctaccatgg ccttgtggaa gcgtttatgc agtctatgaa
    35221 tcaagcgacc cttctttgtc aaatgcagat gcaccacacg acgatcctgt tctgaccgaa
    35281 ctcgctcaat gtagccctta cgctctaaat tgttcaaact tgtcgtaaca gttccaagag
    35341 ttaccatcaa ctcttttgac acttgacttg gagtcacatc tggagcctta ccgatgacat
    35401 caatcgtatg catttctttg atggagatat ccttaaaacg actacctctc aagttcactt
    35461 cctcaattac aaggacattg ttaaatatag atgttaaata ttcattgatt cgttggtagt
    35521 ccatttttca tatccctcct tcttcaaaaa acttttacaa tcaaaacatt tgacagaaag
    35581 aattatatca aaattcaaag aatgatgcaa gtatttttta ttttcctgta aatttaggtc
    35641 ttcttctctc cgaatgagct cgcactcctt ctttgaaatc ctctgtttga gctaaggatt
    35701 tctgtaggtt cagttctaaa gtagcgtaac cctgccagtc tttaaactgg ctctcccaaa
    35761 ccaacttctt aatggcagca taggaattac ttgaagcacg tcttaatttt ttaagaagct
    35821 gttctctcgt cttttcaagt ttttcagctt cagaaacgcg gtaaaccaac ccccattcta
    35881 gggctttttc tgccgttaaa gcctctcctg tcatagctaa ttgagcagca cgcgtcacac
    35941 cgatactgcg gctcaagaga tgaattcccc ctgcatctgg agccaaacca acaccaacaa
    36001 aggcttggat aaacttagcc ttatccgtcg ccaaacagaa atctgccgca acagccatat
    36061 tcgctgcggc acctgcaaca gcaccgtcaa cttccattaa aacaggtttg gctatttgct
    36121 tgattttata agaaatcgta ttgaccaact ctgcgatttt tgtcaatgat ggaatatcat
    36181 cctcatccac tgcccgcttc atctctacca aatctccccc aactgagaag acctttccat
    36241 tggcattgat taagataaaa tgcacagctg gattttcttc tgccaaagtc agagcttcta
    36301 aaatctcctc acacatggga atatgaaaac catttgcgac ctcaggacgg ttcaaggtaa
    36361 ggattgccaa gtcctcttca agctgataaa taatgtgttc catcagggct cctttttatt
    36421 ttataagcag tttatactct tcgaaaatct cttcaaaccg cgtcagcttc catctgtaac
    36481 ctcaaaacag tattttgagc agtctgcggc tagcttccta gtttgctctt tgattttcat
    36541 tgagtgttaa attatttcac tgtcaaagta tatctttttt aggagcagaa agcaagaaaa
    36601 aatcgactga aagtgtctca gccgataaga aaggctcgct ttaggctaga aagcatctta
    36661 ttttcttcat tgaaaaaagc ctttctttct gctataatcg tataaaatac ttactttagg
    36721 agttcttatg aaagttgtta aatttggagg tagttctctt gcctctgcta gtcaattaga
    36781 aaaagtttta aacatcgtca aaagcgattc agagcgtcgt tttgtagtcg tttctgcgcc
    36841 tggtaaacgc aatgctgaag atactaaggt tacggatgcc ctgattaaat actaccgcga
    36901 ctatgttgcg ggtaacgata ttagcaagag ccaaagctgg attatcgacc gctatgctgc
    36961 tatggttagt gaattgggac taaaaccagc tgtgctagaa aaaatttcta aaagcattca
    37021 cgccttggcc actcttccta ttgaagaaaa tgaatttctc tacgatactt tcctagcagc
    37081 cggtgaaaat aacaatgcca aattgattgc tgcctacttt aaccaaaatg gtatcgatgc
    37141 acgctatatg caccctagag aagctgggat tgtggtcaca agtgaacctg gtcacgctcg
    37201 catcattcca tcaagttatg acaagattga agaattgaca aacaccaatg aagtccttgt
    37261 cattcctggt ttctttggtg tcactaagga aaatcaaatc tgtactttct cacgtggagg
    37321 ttctgatatt acaggttcta tcattgctgc tggtgtcaaa gctgacctct atgaaaactt
    37381 tacggacgtt gatggtatct ttgcagccca ccctggtatt atccaccaac cacactcgat
    37441 tcctgagttg acctaccgtg aaatgcgcga gttggcctat gcaggcttct cagtccttca
    37501 tgacgaggct cttcttcctg cctaccgtgg aaaaattcct ctggttatca agaataccaa
    37561 caaccctgac catccaggta ctcgtatcgt tctaaaacac agtaatgatg aatttccagt
    37621 tgtgggaatt gctggtgact caggctttgt cagcattaac atgtcgaaat acctcatgaa
    37681 ccgtgaggtt ggatttggcc gcaaggttct gcaaatcctg gaagaactta acatcggttg
    37741 ggaacatatg ccaacaggta tcgacgatct ttctatcatt ctccgttctc gccaactaac
    37801 tcccatcaag gaagaagaaa tcctgcgtca gttggttcaa aaggctaaag tagatcatgc
    37861 agaaatcgaa cacgaccttt ctatcattat gattgttggt gaaaaaatga agagccacat
    37921 cggagtgact gctactgcga cacgcgctct atctgaaaac aaaatcaaca tccagatgat
    37981 gtctcaaggt tctagtgaag tttctattat gtttgttgtc aataaagacc aagagaaagc
    38041 agcaattaaa gccctctaca atgccttttt tggagaaagt aaggaagact aagcatggcc
    38101 caatcactta acaaaacagt actcctcagt acgacaggca cttcctacct ctctatcgct
    38161 gggaaagttg ggaaattcct tgtcggagat caggctttgg aattttaccc agatgtcaat
    38221 gtcgaacaat ttatccagat tccttggagc catatcaatc agattggagc caatgtcact
    38281 ggatgcaaaa tcagccgcca cttcgaagtc tttacagaca aaggaaaatt cctctttgct
    38341 tcaaaagact caggtgccat tctcaaaatt gcacgcgaca aattgggcaa tgacaaggtc
    38401 gtcaaacttc cgaccctgat tcagacaatt agccaaaaat ttaaaaatct atttgcaaaa
    38461 aaatagaaac tttagtataa tcatagcaac ggataagtag gttatcttct tctttcagaa
    38521 agtctgcggg tgctgcgagc agataggagg gataggtgaa attctaccgt tagtaacaat
    38581 tacatacaca atcaagtgca cacctgtgaa gttggatgga accgtggccc tgccactcca
    38641 acgttttgtc aggtgtgctt ttttcataaa ggagttctta tgttagatat caaacgtatt
    38701 cgtacagatt ttgaagctgt cgcagaaaaa ttagctacac gtggtgtaga tgctgctgtc
    38761 ttgaatgaaa tgaaagaaat cgatgctaaa cgtcgtaaca tcttggtcaa ggttgaaact
    38821 ctcaaagcag aacgtaacac agtttctgct gagattgccc aagctaagcg caacaaggaa
    38881 aatacagatg acaagattgc tgccatgcaa aatctatctg ctgaggttaa agccttggat
    38941 gctgaattgg cagaaatcga tgctaaattg acagaattta caacgactct tccaaatatc
    39001 ccagctgaca gcgttcctgt tggggctgac gaagacgaca atgtggaagt tcgccgttgg
    39061 ggtactccac gcgagtttga cttcgaacct aaagctcact gggatctcgg tgaagacctt
    39121 ggtatccttg actgggaacg cggtggtaag gtaacaggcg ctcgcttcct cttctataaa
    39181 ggcctcggtg ctcgtttgga acgtgctatc tacaacttta tgttggatga acatggaaaa
    39241 gaaggctata ctgaagtcat cacaccttac atagtcaacc atgattctat gtttggtact
    39301 ggtcagtatc caaaatttaa ggaagatact tttgaactca gcgataccaa ctttgtcttg
    39361 attccaactg ctgaagttcc tctggcaaac tactaccgtg atgaaatctt agacggcaaa
    39421 gatcttccaa tctacttcac tgctatgagt ccgtcattcc gttctgaggc tggttctgcc
    39481 ggtcgtgata cgcgtggctt gatccgtttg caccaattcc acaaggttga aatggtcaaa
    39541 tttgccaaac cagaagaatc ttacgaagaa ttggaaaaaa tgacagccaa cgctgaaaac
    39601 attcttcaaa aactcaacct tccataccgt gtcgttgctc tctctactgg agatatgggc
    39661 ttctcagctg cgaagactta cgacttggaa gtgtggattc cagcacaaaa caattaccgt
    39721 gaaatctcaa gctgttcaaa cacagaagat ttccaagccc gtcgtgccca aatccgttac
    39781 cgtgatgaag cagatggcaa ggtgaaactc cttcatacct tgaacggttc tggacttgca
    39841 gttggacgta cagtggctgc aattcttgaa aattaccaaa atgaagatgg ttctgtgacc
    39901 atcccagaag cacttcgtcc atacatgggt ggagctgaag tcatcaaacc ataaaaaata
    39961 aggtttagct atttctagct agaccttttt tcgtaaccaa atcagataag cacctagtac
    40021 aaagaataaa atagttaggc atataatggt ttcagccaat accaggtaat ccagaaatgg
    40081 aagtttcaaa attccctgag ccatcttgag cgaggtcgct gtgataatgg ttgggaaggt
    40141 gagggctgag aaggctggtt gaaaaccttg ttttaaaatg ttgggcagac gagttaaaac
    40201 aaagaaaaag aaggattgag aagccaaaat catgacaatc aagacccaat tcggcaggct
    40261 ggttcctcct actcgaacta gagaagccaa gagtagagag aaaggagcac agtagattcc
    40321 ttcttgtcca agcaaggcta gtgggagtgg atgtttcttt aaatcgctat aaataagggg
    40381 atagagatag aaggtcaaga gaaaaccaaa actcaaggtc gcataggcaa tttcgataat
    40441 acctaccaga ggataggtca aggcagccac tgctatcccc acatagagaa ccgtccaact
    40501 tggagtggca tgaaccctcc gccctgaaca agcaaacttg atggtaaaac cagcaatcaa
    40561 ggtcaaatcc aagagaaatg aaaaccacca aatcccttgt gctaccaaag gaagataaga
    40621 gaatacgcga aagacatagg tcgataaaat catcccagcc ataggaaagg ttgccattcc
    40681 tgacaaaaga gggggcttgg tcaattcttg cttggtttct ttccaattaa agagatgcag
    40741 aattagaaag taaatccata aaaccaaacc agtcagacta aaaagatggg atagaaccgg
    40801 caacgtatct aaaataagat ttccagctcc tgccaaacct agcaaacaac ctgaaaatac
    40861 taaggggagt tttttcatcc taacctccaa taatcatgtt agtttcagta taacataaaa
    40921 gcgcttaaat gatgatttaa aaaaacgaag tccgattatt tcagacttca ttttactcag
    40981 atatgaatta ggcataaggt tgcaattctg gattaattgg tgtattagct aagttgttgg
    41041 catagttaca gaggattgct aggctgacac caaaaaccac atccaaggca ttttgttgag
    41101 tgtagccagc ttctaaaaac tcagacaagg cttcatctcc tacacgaccc ttggtattga
    41161 taactgccaa ggtaaactta gctagggtat ccaatttagg atctgtttca attggagtac
    41221 gattgcgaag agcttgaatc aagtcatcat tcatctggat ttgtttgatg gaaaaggctg
    41281 tgtgacctgc gacacagaag gcacaaccat tggtcacggc tgccgtgatt tgcaccactt
    41341 cacgctcaac gggtgtcagg ctgttgcgac ggtggataga tgagacaatt tggtaggctt
    41401 ctaaaacagt cggggcattg gccaagagac cgattaggtt gggaatatag ccattgttgt
    41461 ctttttctac tgtttcaaga atttctttca cttctgctgg tgctgactct actgtatgga
    41521 tagtaaatgt tgtcataaga tacctctttt cttattattg acactaatat tattggaaaa
    41581 tcttataaaa tcctgattcc taagtttatc taagataaag ctttattctc tcataagatt
    41641 ttcgttgtta tattagttta tcacacttcc aatcacttgc ataatatata ttatatatca
    41701 ggctgataaa aattatttat aggcaaaaaa atcacacgag ctgtgtgatt ccattatttg
    41761 tcaaaatact ttttagtttc agcaataacg acttgcgaca agaccaagag ggcaatcaag
    41821 tttggcagag ccatcaaggc gttaacgata tctgcgataa tccagaccat atccaactcg
    41881 ataaatcctc ctaacaagac catgagcaca aaaaccacac ggtagagcca gataaagcga
    41941 accccaaaga ggaactcaaa acagcgttct ccgtaatagt tccaacctag aatcgttgta
    42001 aaggcaaaaa gtacaaggaa gatggtcaag agggcaggcc caaagtgtga aaagactgtt
    42061 gagaaagctg actgagtcaa ggcaacccca ttcaagtcac cactccaaac tccagttacc
    42121 aagatggtca aaccagttag agtacaaatg atgagggtat caataaaggt tcctgtcatg
    42181 gaaatcaaac cttgctctac tggttcattt gtcttggcag ctgcagctgc aataggagca
    42241 gaacccagac cagattcgtt tgagaacaca ccacgcgcca caccattttg aatagccatc
    42301 cgaacgctag caccagcaaa tccacctacc gcagcaaggg gactaaaagc tgaggtaaag
    42361 actaaagcga ttgtgccagg gatttttccg atattaaaga aaataactat aagagttcct
    42421 aagatataaa tgatggtcat aaaaggaaca acagtagttg aaaccttaga aatagacttg
    42481 agtccaccaa agactgcaat cgctacaaag acagacaaga cgagagctgt gatgactggc
    42541 gaaatcgtcg ttgtattttg gatagattct gtaatcgagt tgacttgggt gaaggttccg
    42601 attcccaaga gagcaaccaa tactcctgct actgcaaaca aaacagcaag tggtcgccac
    42661 ttttctccca tccctagaag gatatagtgc atgggacctc ccgctactgc accatggtcg
    42721 tccttggtgc ggtatttgat ggccaagagt ccttccgcat acttggtagc cattccaaag
    42781 aaagccgcca tccacatcca aaatagagct cctggtccac caaccttgat agccgtcgca
    42841 actcctatga tatttcctgt tccaacagtt gatgccaagg ctgtacacag agctgcaaaa
    42901 ctggatacat caccatgtcc cttatcctgg ataaaaataa gctgaaaggc cttgggcaga
    42961 cgcaaaacct gcaagagtcc tagccgcatg gttaggtaaa tccctgttcc gaccaataaa
    43021 atcaagaggg gcggtcccca agcaaaatca tcgattgatt taagcaattc taacatttcc
    43081 ttctcctatc gtttcaaccc caaaagaaag agcacatgca agatacatgt actctggaat
    43141 gcttagataa atgctaaaaa gcggtctatc ctagctctgt ccttttacct gagagtttga
    43201 gcagttgcct gccttgcccc ttcggtgcct ttacggtctc tccagagttc cgtccattta
    43261 cagtcatgga aaatcaaacg attccccact tctattaaac ttcattcggt gttggtattt
    43321 aattgattct aattttacaa aaaatgttgg cttttgtcaa tgtgtttatt agtaaaaatt
    43381 agttcaacag tttttacttt ataaagtcca gaatactgct atcctttaaa agtgacaata
    43441 gtcgcaccac tgcctccagc attttgtggg gcatagccga aactcttgac atgtttgttt
    43501 ctttgcaagt atttggtaac tccttcacgg atgactcctg ttccgatacc atggatgata
    43561 tcaacttgag ccatattgtt aagcaaggct tggtcgatga aggtatctag ctcattcatg
    43621 gcttcttcat agcgcttgcc tcgaagatcc agtctagctt gaggtcctcg cccagaagtt
    43681 cgtttcacaa cattgacctg tttcttcttg actggttttt cttgctgggc ttgaacaaga
    43741 tcaaactctt tctcttccaa ggtcatctta atcaagccaa cttgggcttc ccagcggccg
    43801 tccttgagtt gactggtcaa ggtaccacgc tgaccataac tgagaaccac gatatcatct
    43861 cccacctttg gagctcgttt tttcttggcc ttttgaagga ccttgttttt agacaagtcc
    43921 actttttcag gagccaattt tttcaacttg gccttggctt caatgatttc gtggggcttg
    43981 agttgggatt tactgtggag atttttgaga atctggtcac tttcacttag ggccatatcc
    44041 acaatctcag cagcctgttc acgcgccttg ttaagctcgg tttccttttc acgattaagc
    44101 tcgttgtaga gtttttttag cgcacggttc atcttgagat tttcttgctc cacctcacgg
    44161 atattgtcca aacgtttgcg gctttccagc gtctgctctt ctaattgctc aatgatacga
    44221 ttgacgtcat tgtcctgatc gatctgctga ctggcatctc ctacgataac ttcagatagg
    44281 cctagacgtt tggcaatttc aaaggcatta cttcggccag gaacaccctg cataaagcga
    44341 taggtcgggc gaagagttgc agtatcaaac tccatactgg cattttgcac aaaggctgtc
    44401 tcaataccgt aggccttgag ttctggatag tgggtcgtcg ccatggtctt gatttgacgc
    44461 aggcgaaggt cctccagaat agccatggca agggctgctc cctcttgggg atcagtacca
    44521 gcccccaact catccaaaag taagagtgaa tgttggttga ccttgccaag aatatccacg
    44581 atattggtca tatggctaga gaaggtagac aagctctgct caatagactg ctcatctcca
    44641 atatcagcaa agatttcttc aaaaatacca acacgacttc ccttgtctgc taaaatcggc
    44701 aatcctgact gggccatgac ctgtgtcaag cccagagttt tgagcatgat ggtcttccca
    44761 cctgtattgg gacctgtaat gacaatagct gttaaatctt gaccaaaata gacatcattt
    44821 gcgacggcat ttttgaccaa aggatggcag acatggagca gttgaatctc ttgattttct
    44881 gacagctgag gcacgactgc ttgtctttct tggataaatc gaaccttggc acgaatcaag
    44941 tccagatgac cgataatcca agcgtcatta gcaatctcag ccgcatgagg gcggacacgc
    45001 tcagaaattt cttggagaat gcgaagcatt tcatagcgct catctgctcg cagactagca
    45061 atttcttcgc tcagtttgac tacctcacgt ggttcgatat agacggtgtt tccactagca
    45121 gaaatatcat gaacgacacc tgcaatctta ttgcggtagg tgtttttgac tggtaaaacc
    45181 tgacggccat ttctgctagc aacaattcct tccgtcaaca tctgcgcttt ttgcttgagt
    45241 aagtcttgta aaacatcgcg cacctgactc tcgctatcat gtatttttcg acggattcgc
    45301 gccaattctt cactggcaaa attttcaatg aaacccgcat cattaaaggc ctgaagattt
    45361 ccttgtaatt gcggaaaatc atgtaatttc tcaaaccaaa gggctaattc ttccaagctg
    45421 acattttcca gattggcgta aaaattttga agttctcggc tggcaagaag cacgcgtttc
    45481 aagagtagga actcctcgat attgagatcc gctcccatct ccaacctctt gcagactcct
    45541 gcaatttcct tagttgagag aatagtaaaa tgcggttgct cgacgaaaag agcctgcatt
    45601 tctttcatct cagcaaaagc ctgtttgatt ttatctgctt tggcagtcgg agccagctgt
    45661 ctcaattgct ccaagccctg ctcggtcaac aaatgaggct caaacaaggc cttgacctta
    45721 tcgaactcta atgtttctaa tattttctta ttcatcttta tttccttgtc tttgaatgtc
    45781 taggtgtggt agctttttac attctgatag attcgagtca aatctgtaaa caaagggcta
    45841 ggaaaactcc tgcccttttt atccgattaa atttgtcacc cagatttgtt tgagccaact
    45901 ggttgttacc ggtatgctct ggatgatgtg ttttgcgacg atactctttt caagaggatt
    45961 ttgtataact gccatgggga tggtcgccaa gattgtcaag gccatttgca agacaaataa
    46021 ggtcaccaac atggacaaga tacctgctga aacttggaac aacttaccac ccagtttttt
    46081 gctaggaatc aagtgtaaga gaagaccaag taaacgacca atgctataga caatcccaaa
    46141 tacaagcaag tagccgatac ctgcataaaa gaccttatcc agctgaaaga gttgatccga
    46201 tgggaaaaag aaagtcccct gaccttcctg cgaatttgca taagggagca ataaatggaa
    46261 ttgctctcca agccccttat aaaactggcc agccataaaa gccgatgcca tggctgaaat
    46321 caggtaataa acctgtaaga gcaggcctct ccgatagccg atataaaatc cccaaaccaa
    46381 gaccaataga agaaggaatg aaatcataag gaatcctcaa tcttgctctg ttcttgctta
    46441 caagtcacaa gcttgtgacg gagttcttct agctcttgct ccttatcgtc aaattcaatc
    46501 tcacggctga gctgagttga taaacagttg actgccaaca aaagagcgat tgtttcatca
    46561 tctgcgctag gcatttgttc tttaattgct tggtattttt ctgtcgcaac cttagcgatt
    46621 tcctccataa aaaggttgtc atgttcgctt gtcaaggtta acgatttttt cccgaatgta
    46681 aatttgaatc gatttagatt tgccataaaa ttcacctcac gatattatac caaaattcgc
    46741 taattttgtc agtttttaca aattttactg cttttgtggt acaatagaaa ctatggcaag
    46801 tatcacactc acaccaagcg aaaaggatat tcaggctttt cttgaacact atcaaaccag
    46861 tctggctcct agcaagaatc cctatatccg ctactttttg aaactacctc aagcaacggt
    46921 ttctatctat acttctggaa aaatcttgct tcagggtgaa ggggctgaaa aatacgccag
    46981 tttctttggc tatcaagctg tagagcaaac cagcggacaa aatcttcctt taattgggac
    47041 agatgaggtg ggaaatggtt cctactttgg tgggcttgca gttgtggctg cctttgtcac
    47101 acctgaccag cacgactttt tacgaaaact cggtgtgggg gattctaaga ctctgaccga
    47161 ccaaaagatc cgtcagattg ctcctattct caaggaaaaa attcagcacc aggcactcct
    47221 tctctcaccc agcaagtaca acgaggtcat cggagaccgc tacaacgctg tttcggttaa
    47281 ggttgccctc cataatcagg ctatctatct cctccttcaa aaaggtgttc agcctgagaa
    47341 aattgtgatt gatgccttta ccagtgctaa aaattatgac aagtacttgg cacaagaggc
    47401 caatcgtttc agcaattcta tcagcttaga agaaaaggct gagggcaaat acttggctgt
    47461 cgcagtttct tctgtcattg cgcgtgatct ctttctggaa aatcttgaaa atttgggacg
    47521 agaactgggt tatcagcttc caagtggagc tggaacggct tctgacaagg tggctagcca
    47581 gattttgcaa gcctatggta tgcagggact caacttctgc gctaagctac actttaaaaa
    47641 tactgaaaaa gcgaaaaacg cttagaaagg taagttatga atttatttaa aaatttctta
    47701 aaagagtggg gattattcct cctgattctg tcattactag ctttgagccg tatctttttt
    47761 tggagcaatg ttcgcgtaga aggacattcc atggatccga ccctagcgga tggtgaaatt
    47821 ctcttcgttg taaaacacct tcctattgac cgttttgata tcgtggtggc ccatgaggaa
    47881 gatgggaata aggacatcgt caagcgcgtg attggaatgc ctggcgacac cattcgttac
    47941 gaaaatgata aactctacat caatgacaaa gaaacggacg agccttatct agcagactat
    48001 atcaaacgct tcaaggatga caaactccaa agcacttact caggcaaggg ctttgaagga
    48061 aataaaggaa ctttctttag aagtatcgct caaaaagctc aagccttcac agttgatgtc
    48121 aactacaaca ccaactttag ctttactgtt ccagaaggag aataccttct cctcggagat
    48181 gaccgcttgg tttcgagcga cagccgccac gtaggtacct tcaaagcaaa agatatcaca
    48241 ggggaagcta aattccgctt atggccaatc acccgtatcg gaacatttta agaaacctaa
    48301 gaggccgaga atcaccaatc tcagcctctt cttctatcgt gagaaaatga ttggtaacta
    48361 tctaaactta ccagaacaga aacacctcaa ctctcaccta ttcatgcaaa ggaattttat
    48421 ggaagtttat ttttcaggaa ccattgaacg gattattttt gaaaatccca gcaattttta
    48481 tcgcatcctc ctcctagaaa tcgacgatac ggacgcagag gattttgatg attttgaaat
    48541 cattgtcaca ggaaccatgg ctgatgtaat tgagggcgaa gactatactt tttgggggca
    48601 aattgtccag cactccaagt atggagaaca actgcaaatc agtcgttatg atcgcgcaaa
    48661 accaactagt aagggcttgg tcaagtactt ttcaagtagc catttcaagg ggattggtct
    48721 caagacagct cagaaaatcg tggataccta tggcgaaaat accattgacg aaattttgca
    48781 acacccagaa aagttagaag gcatcgcagg attctctgcc aaaaatcgcg aggctttcgt
    48841 ctccactctc cgtctcaact acggaacgga gatggttttg tccaaactag ccaactacgg
    48901 cattcccaac aaactagcct ttcagattca agacttttac aaggaagaaa cccttgatgt
    48961 ggttgaaaat tatccctacc agctggttga ggatatcaag ggtttgggct ttacaattgc
    49021 tgaccaacta gctgaggaac taggcatcga aagtcaggct cctgaacgct tccgcgccgg
    49081 tctagttcac agtctttttc aggcctgtat ggaaacaggg gacacctatg ttgaagcacg
    49141 ggatttgctg gaacaaaccc ttactctcct tgagtcttcc cgtcccgtgg aactagaccc
    49201 cagccaagtt gcccaagagc tctcctacct gatcgaagaa gacaaggttc agcagattga
    49261 taccaagatc tttgacaaca gcctcttttt cgctgaggaa ggtatccgca gtcacttgat
    49321 tcgtatcctt gaaaaaggaa aacagaagag ccaagattta gaaactattc aaaagcatat
    49381 cactactgtc gagcaagagc tgggaattga gtatgataac attcaaaaac aggctatctg
    49441 tgatgctatc cagaataagg tctttatcct gacaggtgga cctggtactg gtaagacaac
    49501 tgttatcaat gggatcatcg ctgtttacgc cctgttagag ggacttgacc tcaggaagaa
    49561 aagcaatctg cccattcttc ttgctgctcc aactggacga gccgctcgcc gcatgaatga
    49621 attgacaggt ttgcctagcg cgaccataca ccgccacttg ggaatgacag gtgacgatga
    49681 taccagtcat ctggaagatt acctagatgc tgactttatc atcgtggatg aattctctat
    49741 ggtagatact tggctggcca atcaactctt ctccaatatc tcttctaaca gtaagatcct
    49801 catcgtaggt gacagtgatc agctaccttc tgtcagtcct ggacaggttc tagcggatct
    49861 gcttcatatt cctttgattc ctcagactcg cttggaaaaa atttatcgac aaagcaaaga
    49921 atcaaccatc gtcaccctag ctagtcagat tcgacagggc atcttgccag ctgatttcac
    49981 ccaaaaaaaa gctgaccgtt cctactttga aattgctagt ggccatattc ctgccaccat
    50041 tgaaaaaatc ttaggtgtcg ccctcagaaa tggtattcct gcccgtgata tccaagttct
    50101 ggctcctatg taccgaggga cggcagggat tgatgctatc aatcagctca tgcaagacct
    50161 gctcaatccc ccacaaaaag atcaactcag ttttgaagct cctcagtgcc actatcgtaa
    50221 gagagacaag gtcattcatt tggttaacga tgctgaaatc aatgtcttta atggggattt
    50281 aggagctatc acagacctga ttcctggtaa atacaccgaa tcgaaacaag acgagattgt
    50341 cattgatttt gatggtaatg aagtctctta cccccgtaac gaatggtaca agattcgctt
    50401 ggcctatgcc atgagtattc ataagtctca gggaagtgag ttcccagttg tcatcctacc
    50461 gattactagt gctagccgac gtatgctgga gcgaaatctc atctacacag ccattacacg
    50521 tgccaaaagc aaactcatct tactaggcga attacaagcc ttcgactatg ctacccaaca
    50581 catcggaact gcccgaaaaa cctatctgat tgaacgcttc agtgatctac tggagaatgt
    50641 tgaagaaaag caacaagctg tctctgaaac agtcacatca agtgcctctg aacaatccta
    50701 catcctaacc gaagaaaact gggaccgcat cccagccatg attgggatta cagacacaga
    50761 cctcaaagag atttttggaa aatagtgcat cagaaaaccc accaattcag gtgggttttc
    50821 tgtttattaa gattatttta ctgttgctgt gcttgtgatc aattcaacag cttttttgat
    50881 agtgatatca tgtttcaaca tgtcagctga aagcaagttt tgaacttgtg caacttccat
    50941 gttgtagtct gctgccaatt gctcaacttc tttttggatt tcttcttctg aagcatcaaa
    51001 tccttcagct ttggcaactg cttcgataac aaggttagtc ttagtacgtg actcagcttc
    51061 tgcttggtat tggttgtgaa ggtcttcttg agtagttcca gtgatttgga agtacatgtc
    51121 agggttgatc ccttgacgtt gcaaattccc aaggaattca tttactgaac ggtgaacttc
    51181 ttcatggatc atttcttctg gaagttctac gatttcagca ttttctacag ctgtatcaat
    51241 tgctgcacct tcaactgcat ctttgtaagc ttcttcttta gcagcagcca attctttgcg
    51301 gtatttttct ttcaagtcag caagtgtttc aacttcttca tcaatgtctt ttgcaagttc
    51361 atcgtcaaga gctggaactt ctttagcttt tacttcgtgg atagttgtca cgaatttagc
    51421 ttctttacct gcaaggtctt ctgcttggta gtcttctggg aatgttacga taacatcaac
    51481 ggtttcgcca gctgagtgac ctaccaattg gtcttcgaaa ccagggatga attgacctga
    51541 accaagtcca agtgagaagt tttcaccttt tccgccgtca aattcaacac cgtcgataga
    51601 accaacgaag tcgatcacaa cagtgtcgcc gttttcagca gcagcttcct tgataaccaa
    51661 ttcagccagg ttgttgcgtt cgcgttcgat acgctcttca acatcagcgt cagttacttc
    51721 tttttctaca tcaactgata cttcaaggtt tttgtagtca cccaatttta cttcaggttt
    51781 tgtaacgact tcagcagcga taacccagtc ttgacctttt tccattgaag ttacgtcaat
    51841 ttttggttgg gcaaccactt caagaccagc ttcttttaca gctgcttcat aagcgtttgg
    51901 caaaagagcg ttcataacgt cttggtaaag tgattcttca ccaaattttt tatcgaagat
    51961 aggacgtgga aggtgacctt tacggaaacc tggaacatta agagatttct tcactgactt
    52021 gaagacacgg tccaattctg gtttgatttg gtcttgagag atagtgaaag tcaagacacc
    52081 acggtttgtt tctttgtttt caaatgatac agacattctg tcatttctcc ttaaaatttt
    52141 ttaaatacag tctattataa cattttctat aaataaaatc tagactaatg cagccaatta
    52201 tagacaacaa gcctttttcc taactaaaac actcataaag tatagacaat tttagactac
    52261 tttggatatc ttttggttag tcattttcca aaactaattt atctaatttt tcagttatat
    52321 ttgacttcat cttctcagta acatgagtat aaacacttaa aatctttgtt tcattagtat
    52381 aatctacacg atccattatc gctgttatag gtacttccaa ttcagcaagc aaacttatat
    52441 gcgaatatct aaaaacatga gcagtcaata caaaatcatc tttcttaatt tcacttttcc
    52501 taaaactgtt tttcaaaaag taattgaaac aagttatcat taagggagaa ccattatttg
    52561 taaatatata atcaccttct tctaaaagaa gatattcttt taaaatttct aacactctat
    52621 cactaatacc aattactcta tatgaagcta aacttttcgg actatccaaa aatacttcgt
    52681 tattggacga ttacattata gtaaaacgaa ataagaacag gacaaatcga tcaggacagt
    52741 caaatcaatt tctaacaatg ttttagaagt agaggtgtac tattatagtt tcaatctact
    52801 atacaagacg aaattgaaga aatctttcca ttataaaacg catattatca aggtttttaa
    52861 acacctaata atatgcgttt tttcctattt taaagacttt tatccaccta ttatacaaag
    52921 ttaagtatcc atcacagttt acaattagcc ttcattacct aacccattca ccatccttca
    52981 agagagtaac ctttaagaac cgaataaata aatggcaaat ttcgttcatt taatttaact
    53041 gcactgttaa tttgattagc tccatctcct aaagtatgca ctcctactac acggtgacta
    53101 gcatcataaa ctgtagatcc actagacccc tctaaagtat caacttggta atccaagaac
    53161 atgccatcat cacttaaaac ttgtttttta tctgtataca tttgatgaat tttaaaatta
    53221 tatgatagat agcctgtgat agtcacagtt attcctgtca aatttttttg actagtagga
    53281 agacccaaag tccctaattt tgcaccaatg ggctcttcta gaattaataa agccaagtca
    53341 tattcccttg catccttaga atttaaattt ctaaattcct tcaaataacg aacttccttt
    53401 actttgatct ttccaaatag ttcttgactt ggactaacag ccggaagaac ataaatatca
    53461 tccgcttctt tcccatagtc atgtctgtag tagttgtgag ccgctgtaat taacacatta
    53521 tctttaataa aattcgcact tcccctccct tctacattca ttccatcggc tactccataa
    53581 tacttagata aaaccatagc tgaagtcgaa tacggatact gtaaagtatt atcaatttta
    53641 atcaaatcat cattaccgat aatacttctg attgcttttg gtagtatgaa ccatacgttg
    53701 gtgaaatctc agataatgaa gaatcattag actctggacc tttttctagt gtctcactta
    53761 cctcatattc ttcacctgta ctagaaataa cactcaaagc agatactgtc gataactggc
    53821 tagccaataa agtactcgca ataattgaaa tacccaattt tttataaaca gttttcttca
    53881 ttattgtatc ctcctaatgt aattatagcg tactattcta aatttcttaa tctactatag
    53941 aatcaagaaa tctaccacct tctttaaata ccctccatta tcacataaac aggtaaactt
    54001 ttcaattaat gactgcgctt ttcaatcacg ctagaggtac ttgcttgctt ctttgatact
    54061 aagttcagcc attctttcct tgtttttctc aataaagcat gttacccaag tgggattcgt
    54121 tttggagtag tctcgcagag tccagccaat ggctttattg ataaaaaatt ctgtttggtt
    54181 caagttatga agtagaatct tttccattaa ttgagtattg gtcttctctt ttcttaacaa
    54241 ctggtggtca atagcgacac gtctcagcca gatattatct gataggctcc attttatact
    54301 caatgaaaat caaagagcaa actaggaagc tagccgcaga ttgctcaaaa cactgttttg
    54361 gggttgcaga tagagctgac gtggtttgaa gagattttcg aagagtatta agattatttc
    54421 ttctagttca gagtgttcat acaccaaact ccctactact cgatctagga tatctaccgt
    54481 gtcccaccag gattttgtca cgactaactg ctctagctta ggcaaatcgg tttcctttag
    54541 ataagactgc attgctttca aatagttagc agccacatat tggtattctc taggatcctt
    54601 ttcccagcaa gtgtctgcaa aatcccaatc gataatcttt gtttttttcg cttctggaaa
    54661 atatttttat agagtttatt tctttcaggc accgcaatac ctagaaaaga aaattgatgg
    54721 cgcatatagg cttccatgga ccttgctttt ttagagtctt ttgctgcttc tagctcctca
    54781 agtaaatctg ctaaactcat ctaaaactcc tcttgcccca ccaaatggtg ctgaaaggca
    54841 tagacagccg cctgggtacg atcgctgact tcaagtttgg caagaatatt ggacacgtgg
    54901 gtcttgaccg tcttgagaga gataaagagg tcatctgcga tgcgctgatt ttcgtagccc
    54961 ttggcgatga gttggagaac atctcgctca cgcgcagtca attcttcatg aagttccata
    55021 tgattgcggt ggtattcaac cttcttgcta acctcttgct caatggccag ctcgccagca
    55081 gctaccttac tgacggcatg aagcaattca tctgcactag aagtcttgag catatagcct
    55141 ttggcaccag catctaagac tggcatgatt ttttcattgt ccaaataaga ggtcacaatc
    55201 aaaatcttgg cttcaggcca ttctttaagg attgctaagg tcgcgtcaat cccattcatc
    55261 tcaggcatga caatatccat gacaatgaca tctggacgca gttccaaggc caagtcaatc
    55321 ccttgagacc cgttggacgc ctcacccaca acttctacat cgtcttggag gtcaaagtag
    55381 cttttcaagc ccaatcggac catttcatgg tcatctacta gtaaaatttt catctttact
    55441 cctttatcat tccttatcta acaggggaat acggatatca accgccagcc cttgcttggg
    55501 agctgtcaag agttgaactg ttccagccat atcttcaacc cgctccttga tatttcgcag
    55561 tccataactc aagtcgtcta agctccctaa ctggaaacca atcccattgt ccaccacctt
    55621 cagttgcaat tcaacatctg tctgatagag gtagacatct aggcaagatg cctgggcatg
    55681 gcggagggta ttgctaatca actcttgcag gatacggaag atatgctcct cgattttctt
    55741 aggcaatttc gtcatattct gcttgagact aaccctaaga tcactcttgt cctcaagctc
    55801 ttttaagaga atttgaatcc cttctatcaa gctcttctgc tccagttcaa ctggtcgcaa
    55861 atgcaagagc aaaacccgca aatccttctg ggcagtttct aaaatagctg tgacactctg
    55921 caactggatc tgcatctttt ctctatccaa tttcaaagcc tgctgactga tacccgataa
    55981 aatcatgtgg gccgcaaaca actcctgact gactgtatcg tgcaaatccc gagcaattcg
    56041 cttccgttcc ttctcgatga tttcctcttc ctgagcaagg ctatgatttt cagctttttg
    56101 aagagcttct gtcaaaaggt taagtttacc tgataaggac ttgaaactgg catccaaatc
    56161 tggatctgca acctgaacca cttcttgccc tgccaataaa cgcttgagat tagcctgcat
    56221 ttttcttaga gaaagctctt cgatccctcg ccaaaacagg gctaagagac aggttatgga
    56281 catgctgaaa accaacaata aaaagacaaa tttttctgtt ttttcgacat cgtgcaaaaa
    56341 gatagaccag tcaaaatcaa gtatttccag caagctgtgg gagaaaaaaa agacaaacag
    56401 gaaggaggtg agagcaataa tgacataggc ttgttttttc atcctctaac cacctccaca
    56461 tcaccaatca tagtggtcaa gaaaatcttg acactcttgt tactcttgag atagtctttt
    56521 gtttcttgat gatagtgttc attgcggagg gctcgcttgg gctggttgaa aaaagtcaaa
    56581 tccccataga gacagttaac gctgagactg acttccacat ctacaggtac gatgattttg
    56641 gtcgttccta ccatctttct gaggataatg acattgtcat gattggttaa gatgaccctc
    56701 tccagatgaa tagtgtcctt gcccatgaag cgaaagagat tgatatcatc gaattggcaa
    56761 gtctggtagc ttgaaaaatg atgaagattt ccaaaccaac gatttttctc cttcttaacc
    56821 gtcacgacct cttcaaaaac caaattggtc tgctcttttt cctggttcat catcgggtaa
    56881 agaagaaaga ggctatagat aaccgcaaca aaaatagcta gaatcacaaa aggattgagc
    56941 ataacgatga aaaagaagag aatggttgcc gctactaaaa gaagattatt tccctcttta
    57001 ccagtgtagt agcgaatcaa aagcaaaaag aggaatagta tcagcagaaa acgcgaaaaa
    57061 tgctctgata ccatcaaaat cagagctcct gtcagaagac aggcttcgat aaataaaaag
    57121 attttaaatt ttctcatagg ttcatcctct cccttctatt ttatcacaat tcaaaaaagt
    57181 cacctcagtc tgaggatgga aaaaaggcgc tggttacgcc tttttcatct gatcctttgc
    57241 ttcttttaat tttccataaa gaagatagtc tactttttgt agatctgcta tggtggcaca
    57301 gttaagggaa cacataatca agcgtaggtc tgctttccag ccttggacaa tgccaatcac
    57361 ttcttcaact gtgtaggttt caaccaattc cagaacggtt cgtgacaatc ccacagactt
    57421 agcaccaaaa accaagcact taatcatatc cagcggattc cgaacccctc cactaaccaa
    57481 gagttcgacc ttatctttcc attcttgggc attgagaagg gcctgcatgg tagactgacc
    57541 ccattgattg aggtaatcac gctggccact acgacggttt tcgatatagg caaagctggt
    57601 gccaccacga cccgataggt ccactgtacg aacaccgaat tcataggctc tttcgattgt
    57661 cttggcatcc attccaaagc ccacttcctt gaggacaata ggaacgggaa tttgctcgct
    57721 ataatctgct agatgcgatt gccagcttct aaacttcctt tctccctcgg gcatgagtaa
    57781 ttcctgcatg acattgacat gcacttgcaa tagaacagga ttcatctctt ctacagtctg
    57841 aagccctaac tcgacaggct tgtccaatcc aatattggtt ccaaggagga gattgggatg
    57901 actagacttg acagaaaaag aatcatccgt tggatttttg agggctgcgc tataagaacc
    57961 cgttacaaat aaaataccac aggattccgc cacctgagcc agcttttgat tgatttctct
    58021 tcccttatta cttccaccag tcatggcatt gatataaaaa ggaaagtccc actttcgacc
    58081 agcaaactct gtcgaaagat cgatttcatc cagattgtaa agaggcaagg aagaatgaat
    58141 cagctccacc tcatcaaagc tattatagga acttttctgc tcaagggcat agaggatatg
    58201 ctcgtcctta cgatttgtcg tcatgtccta tcctttcttg atataagagc tcaatcccca
    58261 gatcggccca acgatttttt aaggtttcgg ttgattgcgc atcaaaactc aaggcgatgc
    58321 cacagtcacc accaccagca ccactactct tggcaacggc ctgcaaatct tgactggctt
    58381 ctttcaactg tctaagcaaa ggcgtgtaaa tatctgtact caagccttct aaaagcttgc
    58441 tggctacttc tacttgctcg ataacttttt cggctttccc ctgctccaag gcttcgacca
    58501 aagaaaccac cgtttctttt gaggaactta aaaaattttg attgatattt tgcttgattt
    58561 gctggaccat gtgactcgat acagccactt ccttggtcca tcccactaag aaatcacatt
    58621 ctaaagttgg tttcacttgt gagataaaaa atccccaatc acgctccaga actgtcgcca
    58681 agttttcttc ttctaaccaa gcagccacct tctggcgatc aaatgactgg tagagaacca
    58741 aatcctctgc cacaatacag gcaaggtcgc ccatggaacc attgtctcct cgcttgagca
    58801 agacagcgct agtcagcttg aacaagagat tctgatcaac cgaaagatta tagagagcca
    58861 gtaaagcctt gacaaccaag acaacgacgc tgccactaga acctagacca aactttttcc
    58921 cttctcgttc cattttgcca cagattttta gggaaaaagg tcttaaattc tgaccgcgaa
    58981 cagcgaggaa gtctcccatc aaagcaatcg tttcttgaat caagctgtag tcaggattag
    59041 gccttaagtc cactgcgaaa tcaaacatat ctgaatagat acggtagctg tcagaaaaag
    59101 caatttcagc cctcatatag atgggaatat cctttatcaa agctaactgc cctggctcta
    59161 aaatagcata ttcacctgcc caatagagtt ttccgcaagt tttaacagca atcatcttga
    59221 ctcaaatcct ttgtttttga cacaatcaag cgataacgct gaccgaaaat ttctgataaa
    59281 tgctccaagt ctttctcctg acagaagacc ttaacattgg gaccagcatc catggtaaag
    59341 tagcaggcct ctcctttctc acgaagctgg cgaacaaagt ccatagcctc ataagaggca
    59401 tccgtcagat aagaaaaggc tggactagca gtctttgtcg tagcatgcat agccagggca
    59461 tttttctccg ttaattctcc aatcttggca aaatcatttt ccttgagata aatcagcata
    59521 tcctgatagt ccttctcaga ctgacgaacc cagtcgtcga aagtcgtcga ggtttccaca
    59581 caaagtttca tcccgtcacg gctagagatt ggttttttct tgtcctctag caccaacata
    59641 atcatagcta gtttcaagtc tgtctctaca gggtaaattt ctccactatc cttatcccag
    59701 gctcctagtg gtccataaaa actccgagaa gaagagcctg aggcaaactt ggcttcctgc
    59761 gctaactgac ttctatccaa tccaagcttg aaataagcat tacaagcctt gaccagggcg
    59821 gacaaaccac tagaacttga ggacaggccc gctgccgtag gcatattgtt ttgagtatcg
    59881 atacggacaa agccctcacc agctggacga taacggtcaa taatcttact catcttggca
    59941 tgctcgacct cattttgtag ctgaccattg atgtaaaatt cgtcagctgt tacattggct
    60001 ggtaaaggcg acaaggtcgt ctctgtatac atattttcca aagttagaga aatactgcta
    60061 gtagcaggca ccatctcttt ttcttttttc tttccccaat atttgataat agcaatattt
    60121 gcgtaggaac gtactgttac aggctctcta tccatgtctg aacagctcct ttctcttcta
    60181 atctttctgc tagttcttgt gcgtgtgtca aattggttac caaggctatg atacaacctc
    60241 ctagcccacc accgctcatc ttggcaccca gagcaccatg gctaagagtc gtttcaacca
    60301 aaaagtctgc ctcagggcta ctgactccaa tttcttttaa atgtaaatgc gcttgactga
    60361 ggatttgtcc cagtccttca gcatcttttt gtgaaatcgc aacttctgct tgctgggtta
    60421 attctcccaa ggcatgcaaa aacggtaggg catccttgcc cttattttga accacttgga
    60481 tggcttcacg agtatgacca taaacacccg tatcggcaat caccaaatag gcggataaat
    60541 ccatctcaag ttctgtaaat cctacgttct tgataaagcg aataggttgg tcactgagac
    60601 aggtcttagc atccaaacca ctaggattca tatgggcaat catttcagct cgattgacca
    60661 agatttctag tacatcatga ggcagatcag cctgatagta gtcaaatacc gcacgaatgg
    60721 ccgctatgct gatagccgct gacgaaccca tcccccgttt ctcagggata gccgagtcaa
    60781 tctcacaacg aatgcaggct tctgtgatat ccaaatactc cagtgaggca taaaccgcca
    60841 tggacaaggt atcctcctca taaaggcgcc aaggactctc tgcaggaact accttacagg
    60901 tcacctccac ctccaaaaga ggcagggaaa tggcaggata accgtaaacg accgcatgtt
    60961 cccctattaa aattatctta ctatgtgcct gaccgacacc aacttttttt gtcatttttt
    61021 ccttttacta gacgaaaaaa cgtcttattt ttcatacaag tattaattct ttcctatcta
    61081 ttttattata ttttcacaaa aaaagcgatt gtttccattc acaatcgctt ctttcattac
    61141 cgaacccatt caccattata attgacagaa tagccatcta caatcgtatt cactgccaag
    61201 gcacctgagc tataagcgta gtaccatctg ccattgacct ggaaccaacc tgtcgtcata
    61261 gaacgatgaa agaaactcca taccattaag taaagaggaa agtcatgagg gagcatgcgt
    61321 cattgacaac ctattttagt gacgtacaaa gtttcattaa caagtactcg tttcggccat
    61381 ttataggtgc ggtgtttgca gaaatagggt tcaatcttcg cccattcttg atcgtttaaa
    61441 tcagtatcat atgctttgcg tgtcataact ctagtttaac atttttttgt gaatacaggt
    61501 tctaaataat cgaccacgaa aatttcttaa gtggaaaacg ccttatgaag tatgctacgg
    61561 gaaacttatg cacttaattt gacaactcaa tatgtaaaaa tatatactat a
//
LOCUS       DAVBOD010000007        59923 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 640-05
            SAMEA1012484-rid20186543.denovo.007, whole genome shotgun sequence.
ACCESSION   DAVBOD010000007 DAVBOD010000000
VERSION     DAVBOD010000007.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012484
            Sequence Read Archive: ERR059358
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 59923)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 59923)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979948.1
            Genome Coverage       :: 595x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:03:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,266
            CDSs (total)                      :: 2,219
            Genes (coding)                    :: 2,091
            CDSs (with protein)               :: 2,091
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 71 of 128
            Pseudo Genes (incomplete)         :: 50 of 128
            Pseudo Genes (internal stop)      :: 33 of 128
            Pseudo Genes (multiple problems)  :: 22 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..59923
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012484-rid20186543.denovo.007"
                     /strain="NIG 640-05"
                     /db_xref="taxon:1313"
     gene            complement(78..536)
                     /locus_tag="VQ862_000423"
     CDS             complement(78..536)
                     /locus_tag="VQ862_000423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3021 domain-containing protein"
                     /protein_id="HET3114824.1"
                     /translation="MKKQVFHDAAAGVLIGLILSILFSLIYAPNTYAPLNPYSLIGQV
                     MDQHQVHGALVLLYCTLIWAAIGMLFNFGNRLFSRDWSMLRATLTHFFLMLAGFVPLA
                     TLAGWFPFHWIFYLQLIIEFAIVYLIIWAILYKREAKKVDHINQLLEHRK"
     gene            complement(533..973)
                     /locus_tag="VQ862_000424"
     CDS             complement(533..973)
                     /locus_tag="VQ862_000424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000861967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET3114825.1"
                     /translation="MKVELQISETYEEEKLIVQAPQPTDKVQKVIEFAENLDQREKIK
                     GKIDDQVYLVEIGKIQRFYIENRKVLAETASQTYSIDLRLYQVLKLLPTNFIQISQSE
                     IINIDSISHLKLTPNGLVEIFLKNESFTYSSRRYLKTIKEKLEL"
     gene            1179..3128
                     /gene="mutL"
                     /locus_tag="VQ862_000425"
     CDS             1179..3128
                     /gene="mutL"
                     /locus_tag="VQ862_000425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair endonuclease MutL"
                     /protein_id="HET3114826.1"
                     /translation="MSHIIELPEMLANQIAAGEVIERPASVVKELVENAIDAGSSQII
                     IEIEEAGLKKVQITDNGHGIAHDEVELALRRHATSKIKNQADLFRIRTLGFRGEALPS
                     IASVSVLTLLTAVDGASHGTKLVARGGEVEEVIPATSPVGTKVCVEDLFFNTPARLKY
                     MKSQQAELSHIIDIVNRLGLAHPEISFSLISDGKEMTRTAGTGQLRQAIAGIYGLVSA
                     KKMIEIENSDLDFEISGFVSLPELTRANRNYISLFINGRYIKNFLLNRAILDGFGSKL
                     MVGRFPLAVIHIHIDPYLADVNVHPTKQEVRISKEKELMTLVSEAIANSLKEQTLIPD
                     ALENLAKSTVRNREKVDQTILPLKENTLYYEKTEPSRPSQTEVADYQVELTDEGQDLT
                     LFAKETLDRLTKPAKLHFAERKPANYDQLDHPELDLASIDKAYDKLEREEASSFPELE
                     FFGQMHGTYLFAQGRDGLYIIDQHAAQERVKYEEYRESIGNVDQSQQQLLVPYIFEFP
                     ADDALRLKERMPLLEEVGVFLAEYGENQFILREHPIWMAEEEIESGIYEMCDMLLLTK
                     EVSIKKYRAELAIMMSCKRSIKANHRIDDHSARQLLYQLSQCDNPYNCPHGRPVLVHF
                     TKSDMEKMFRRIQENHTSLRELGKY"
     gene            complement(3453..3920)
                     /locus_tag="VQ862_000426"
     CDS             complement(3453..3920)
                     /locus_tag="VQ862_000426"
                     /EC_number="2.5.1.78"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001099498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6,7-dimethyl-8-ribityllumazine synthase"
                     /protein_id="HET3114827.1"
                     /translation="MNTYEGNLVANNIKIGIVVARFNEFITSKLLSGALDNLKRENVN
                     EKDIEVAWVPGAFEIPLIASKMAKSKKYDAIICLGAVIRGNTSHYDYVCSEVSKGIAQ
                     ISLNSEIPVMFGVLTTDTIEQAIERAGTKAGNKGSECAQGAIEMVNLIRTLDA"
     gene            complement(3921..5126)
                     /locus_tag="VQ862_000427"
     CDS             complement(3921..5126)
                     /locus_tag="VQ862_000427"
                     /EC_number="3.5.4.25"
                     /EC_number="4.1.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP
                     cyclohydrolase II"
                     /protein_id="HET3114828.1"
                     /translation="MEYRKIQEALEALQKGRLVLVIDDKDRENEGDLICSAQAATTEN
                     VNFMATYAKGLICMPMSESLANQLMLSPMVENNTDNHKTAFTVSIDYKETTTGISAEE
                     RGLTARMCVAEDITPSDFRRPGHMFPLIAKKGGVLERNGHTEATVDLLKLAGLKECGL
                     CCEIMNHDGKMMRTDDLIQFSKKHNIPLITIKELQEYRKVYDQLVERVSTVNMPTRYG
                     NFKAISYIDKLNGEHHLALIMGNIEDEANVLCRVHSECLTGDVLGSLRCDCGQQFDKA
                     MKMIVENGSGVLLYLRQEGRGIGLINKLKAYHLQDQGMDTLDANLALGFEGDLREYHI
                     GAQMLKDLGLQSLHLLTNNPDKVEQLEKYGITISSRISIEIEANPYDSFYLETKKNRM
                     GHILNMEEK"
     gene            complement(5146..5781)
                     /gene="ribE"
                     /locus_tag="VQ862_000428"
     CDS             complement(5146..5781)
                     /gene="ribE"
                     /locus_tag="VQ862_000428"
                     /EC_number="2.5.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000493842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="riboflavin synthase"
                     /protein_id="HET3114829.1"
                     /translation="MFTGIIEEIGKVERIQKDSRNCKLSIKASKILTDIHLGDSIAVN
                     GICLTVTHFNHQSFTVDVMNETWSRTALTLLKHGSEVNLERALSVNGRLGGHVVTGHI
                     DGTGKISSIKKDDNAVWYQINTQKEILDLIVEKGSITIDGISLTVAKVSKVNFSVSVI
                     PHTLEQTILKSKQVGSTVNLENDILGKYVQKLMDNSPKSEISKELLYQNGF"
     gene            complement(5766..6866)
                     /gene="ribD"
                     /locus_tag="VQ862_000429"
     CDS             complement(5766..6866)
                     /gene="ribD"
                     /locus_tag="VQ862_000429"
                     /EC_number="1.1.1.193"
                     /EC_number="3.5.4.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     diaminohydroxyphosphoribosylaminopyrimidine
                     deaminase/5-amino-6-(5-phosphoribosylamino)uracil
                     reductase RibD"
                     /protein_id="HET3114830.1"
                     /translation="MSDSKYMKLAIKLAQKGAGYVNPNPMVGAIIVKDNHIIGQGYHE
                     FFGGPHAERNALKNCRKSPVGATLYVTLEPCCHFGKTPPCIDAIIDSGITRVVIGSLD
                     CNPIVSGKGVKILEENNLQVTVGILENECLNLIKSFRKYITQHVPYVFMKYAMSMDGK
                     IATKTNQSKWITEEEARKHVHQLRHHVSAIMVGVNTVIQDDPLLTCRLEEGKNPIRII
                     CDTHLRTPLTSKIVKTANDIKTYIATSSENKNKMKLYQNHGCEILSIKKKGNHIDLSS
                     LMQHLGNMQIDSLVLEGGSLMNWSALEQQIVDELKIYIAPKIFGGSAKFPVGGEGISL
                     PNDAIRLKPYAFSQIGNDYLIESEVIYPCSQE"
     regulatory      complement(7000..7114)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            7271..7864
                     /gene="ruvA"
                     /locus_tag="VQ862_000430"
     CDS             7271..7864
                     /gene="ruvA"
                     /locus_tag="VQ862_000430"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000271492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration protein RuvA"
                     /protein_id="HET3114831.1"
                     /translation="MYAYLKGIITKITAKYIVLETNGIGYILHVANPYAYSGQVNQED
                     QIYVHQVVREDAHLLYGFRSEDEKKLFLSLISVSGIGPVSALAIIAADDNAGLVQAIE
                     TKNITYLTKFPKIGKKTAQQMVLDLEGKVVVAGDDLPAKVAVQASAENQELEEAMEAM
                     LALGYKATELKKIKKFFEGTTDTAENYIKSALKMLVK"
     gene            7874..8437
                     /locus_tag="VQ862_000431"
     CDS             7874..8437
                     /locus_tag="VQ862_000431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase I"
                     /protein_id="HET3114832.1"
                     /translation="MTKRCSWVKMTNPLYIAYHDEEWGQPLHDDQALFELLCMETYQA
                     GLSWETVLNKRQAFREAFHSYQIHSVAEMTDTELEAMLENPAIIRNRAKIFATRANAQ
                     AFLQLQAEYGSFDAYLWSFVEGKTVVNDVPDYRQAPAKTPLSEKLAKDLKKRGFKFTG
                     PVAVLSFLQAAGLVDDHENDCEWKGLK"
     gene            8434..9111
                     /locus_tag="VQ862_000432"
     CDS             8434..9111
                     /locus_tag="VQ862_000432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000987430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET3114833.1"
                     /translation="MMSNKNKGILIFAILYTILFVFDGVKLLASLMPSVIANYLVYVV
                     LALYGSFLFKDRLIQQWKEIRKTKRKFFFGVLTGWLFLILMTVVFEFVSEMLKQFVGL
                     DGQGLNQSNIQSTFQEQPLLIAVFACVIGPLVEELFFRQVLLHYLQERLPGLLSIILV
                     GLVFALTHMHSLALSEWIGAVGYLGGGLAFSIIYVKEKENIYYPLLVHMLSNSLSLII
                     LAISIVK"
     gene            complement(9248..10279)
                     /locus_tag="VQ862_000433"
     CDS             complement(9248..10279)
                     /locus_tag="VQ862_000433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000255096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LD-carboxypeptidase"
                     /protein_id="HET3114834.1"
                     /translation="MVSTIGIVSLSSGIIGEDFVKHEVDLGIQRLKDLGLNPIFLSHS
                     LKGLDFIKDHPEARAEDLIHAFSDDSIDMILCAIGGDDTYRLLPYLFENDQLQKVIKQ
                     KIFLGFSDTTMNHLMLHKLGIKTFYGQSFLADICELDKEMLAYSLHYFKELIKTGRIS
                     EIRPSDVWYEERTDFSPTALGTPRVSHTNTGFDLLQGSAQFEGKILGGCLESLYDIFD
                     NSRYADSTELCQKYKLFPDLSDWEGKILLLETSEEKPKPEDFKKMLLTLKDTGIFAVI
                     NGLLVGKPMDETFHDDYKEALLDIIDSNIPIVYNLNVGHATPRAIVPFGVHAHVDAQE
                     QVILFDYNK"
     gene            complement(10534..11217)
                     /locus_tag="VQ862_000434"
     CDS             complement(10534..11217)
                     /locus_tag="VQ862_000434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1129 domain-containing protein"
                     /protein_id="HET3114835.1"
                     /translation="MSQIDLQKLTKKNQEFVHIATQQFIKDGKTDAEIQTIFEEVIPQ
                     ILEEQSKGTTARSLYGAPTHWAHSFTVKEQYEKEHPKENDDPKLMIMDSALFITSLFA
                     LVSALTTFFAADQAFGYGLITLLLVGLVGGFAFYLMYYFVYQYYGSDMDRSQRPPFWK
                     SVLVILASMFLWLLVFFATSFLPASLNPVLDPLPLAIIGAALLALRFYLKKRLNIRSA
                     SAGPTRYQE"
     gene            complement(11229..12173)
                     /locus_tag="VQ862_000435"
     CDS             complement(11229..12173)
                     /locus_tag="VQ862_000435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HET3114836.1"
                     /translation="MKQVFLSTTTEFKEIDTLEPGTWINLVNPTQNESLEIANTFDID
                     IADLRAPLDAEEMSRITIEDEYTLIIVDVPVTEERNNRTYYVTIPLGIIITEETIITT
                     CLEPLPVLDVFINRRLRNFYTFMRSRFIFQILYRNAELYLTALRSIDRKSEQIESQLH
                     QSTRNEELIELMELEKTIVYFKASLKTNERVIKKLTSSTSNIKKYLEDEDLLEDTLIE
                     TQQAIEMADIYGNVLHSMTETFASIISNNQNNIMKTLALVTIVMSIPTMVFSAYGMNF
                     KDNEIPLNGEPNAFWLIVFIAFAMSVSLTLYLIHKKWF"
     gene            12305..15136
                     /gene="uvrA"
                     /locus_tag="VQ862_000436"
     CDS             12305..15136
                     /gene="uvrA"
                     /locus_tag="VQ862_000436"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HET3114837.1"
                     /translation="MQDKIVIHGARAHNLKNIDVEIPRDKLVVVTGLSGSGKSSLAFD
                     TLYAEGQRRYVESLSAYARQFLGNMEKPDVDAIDGLSPAISIDQKTTSKNPRSTVGTT
                     TEINDYLRLLYARVGTPYCINGHGAINASSVEQIVDKVLELPERQRLQILAPVIRKKK
                     GQHKSVIEKVQKDGYVRVRVDGEVYDVTEVPELSKSKQHNIDVVVDRIVIKEGIRSRL
                     FDSIEAALRIAEGYVIIDTMDDSELLFSEHYACPVCGFTVPELEPRLFSFNAPFGSCS
                     ECDGLGIKLEVDTDLVVPDASKTLHEGALAPWNPISSNYYPNMLEQAMKVFGVAMDKP
                     FEDLSEEDKNLILYGSDGKEFHFHYENEFGGVRDIDIPFEGVINNIKRRYHETNSDYT
                     RTQMRLYMNELTCGTCQGYRLNDQALSVRVGGQQGPHIGEISDLSIADHLDLVSQLTL
                     SENEAIIARPILKEIKDRLTFLNNVGLNYLTLSRSAGTLSGGESQRIRLATQIGSNLS
                     GVLYILDEPSIGLHQRDNDRLIASLKKMRDLGNTLIVVEHDEDTMREADYLIDVGPGA
                     GVFGGEIVAAGTPKQVARNSKSITGQYLSGKRVIPVPEERRVGNGRFIEVTGARENNL
                     QNVTARFPLGKFIAVTGVSGSGKSTLINSILKKAIAQKLNRNSDKPGKFKTITGIEHV
                     DRLIDINQSPIGRTPRSNPATYTGVFDDIRDLFAQTNEAKIRGYKKGRFSFNVKGGRC
                     EACSGDGIIKIEMHFLPDVYVACEVCHGTRYNSETLEVHYKEKNISQVLDMTVNDAVE
                     FFQHIPKIQRKLQTIKDVGLGYVTLGQPATTLSGGEAQRMKLASELHKRSTGKSFYIL
                     DEPTTGLHTEDIARLLKVLARFVDAGNTVLVIEHNLDVIKTADHIIDLGPEGGVGGGT
                     IIVTGTPEEVAANEASYTGHYLKGKLHHE"
     gene            15129..16190
                     /locus_tag="VQ862_000437"
     CDS             15129..16190
                     /locus_tag="VQ862_000437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HET3114838.1"
                     /translation="MNKRVQAFLAKMQEKELDGIIINNLKNVYYLTGFWGSNGTVFIS
                     RDRQVLVTDSRYIIAAKQETSGFEIVADRDELAVIAGIVKDMNLTRIGFEDEISVSYY
                     HRMQAAFAGLNLLPQTQFVEGLRMIKDEAEIAAIRKACSISDQAFRDALDFIKPGKTE
                     IEIANFLDFRMRELGASGLSFDTILASGINSSKPHAHPMHKPVELGEAITMDFGCLYD
                     HYVSDMTRTIYLGHVSDEQAEIYNTVLKANQALIDQAKAGLGFRDFDKIPRDIIIEAG
                     YGDYFTHGIGHGIGLDIHEEPYFSQTSTETIKTGMALTDEPGIYIEGKYGVRIEDDIL
                     ITETGCELLTLAPKELIVI"
     gene            16322..16720
                     /gene="spx"
                     /locus_tag="VQ862_000438"
     CDS             16322..16720
                     /gene="spx"
                     /locus_tag="VQ862_000438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017768833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator Spx"
                     /protein_id="HET3114839.1"
                     /translation="MIKIYTVSSCTSCKKAKTWLNAHQLSYKEQNLGKEGITREELLD
                     ILTKTDNGIASIVSSKNRYAKALGVDIEDLSVNEVLNLIMETPRILKSPILVDEKRLQ
                     VGYKEDDIRAFLPRSVRNVENAEARLRAAL"
     gene            16786..17355
                     /locus_tag="VQ862_000439"
     CDS             16786..17355
                     /locus_tag="VQ862_000439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HET3114840.1"
                     /translation="MKKIVLVSLAFLFVLVGCGQKKETGPATKTEKDTLQSALPVIEN
                     AEKNTVVTKTLVLPKSDDGSQQTQTITYKDKTFLSLAIQQKRPVSDELKTYIDQHGVE
                     ETQKALLEAEEKDKSIIEARKLAGFKLETKLLSATELQTTTSFDFQVLDVKKASQLEH
                     LKNIGLENLLKNEPSKYISDRLANGATEQ"
     gene            17442..17708
                     /locus_tag="VQ862_000440"
     CDS             17442..17708
                     /locus_tag="VQ862_000440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IreB family regulatory phosphoprotein"
                     /protein_id="HET3114841.1"
                     /translation="MGFTEETVRFKLDDSNKKEISETLTDVYASLNDKGYNPINQIVG
                     YVLSGDPAYVPRYNNARNQIRKYERDEIVEELVRYYLKGQGVDL"
     gene            17712..18131
                     /gene="ruvX"
                     /locus_tag="VQ862_000441"
     CDS             17712..18131
                     /gene="ruvX"
                     /locus_tag="VQ862_000441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002939356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RuvX"
                     /protein_id="HET3114842.1"
                     /translation="MRIMGLDVGSKTVGVAISDPLGFTAQGLEIIQINEEQGQFGFDR
                     VKELVDTYKVERFVVGLPKNMNNTSGPRVEASQAYGAKLEEFFGLPVDYQDERLTTVA
                     AERMLIEQADISRNKRKKVIDKLAAQLILQNYLDRKF"
     gene            18147..18452
                     /locus_tag="VQ862_000442"
     CDS             18147..18452
                     /locus_tag="VQ862_000442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1292 domain-containing protein"
                     /protein_id="HET3114843.1"
                     /translation="MSHDHNHDHEERELITLVDEQGNETLFEILLTIDGKEEFGKNYV
                     LLVPVNAEEDEDGQVEIQAYSFIENEDGTEGELQPIPEDSEDEWNMIEEVFNSFMEE"
     gene            18758..20008
                     /locus_tag="VQ862_000443"
     CDS             18758..20008
                     /locus_tag="VQ862_000443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000464354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional folylpolyglutamate
                     synthase/dihydrofolate synthase"
                     /protein_id="HET3114844.1"
                     /translation="MFEVEEWLHSRIGLNFRSGLGRMQQAVDLLGNPEQSYPIIHVTG
                     TNGKGSTIAFMRELFMGHGKKVATFTSPHIVSINDRICINGQPIADADFIRLADQVKE
                     MEKTLLQTPDQLSFFELLTLVAFLYFREQEVDLVLLEVGIGGLLDTTNVVTGELAVIT
                     SIGLDHQETLGDSLEAIAEQKAGIFKAGKKAVIAKLPPEARLVCQKKAESLAVDLYQA
                     GQDFSVLNGDFSSSLLNLSQLNIGLEGAYQQENAALALQTFLLFMGERKEAIDEQAVR
                     KALEQTHWAGRLERIRPQIYLDGAHNLPALTRLVEFIKEKEQEGYRPQILFGSLKRKD
                     YQGMLGYLTENLPQVELKMTGFDYQGSLDETDVTGYHVIPSYREFISSFEERADAQDL
                     LFVTGSLYFISEVRGYLLDREQIN"
     gene            20005..20547
                     /locus_tag="VQ862_000444"
     CDS             20005..20547
                     /locus_tag="VQ862_000444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001816192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipocalin/fatty acid-binding family protein"
                     /protein_id="HET3114845.1"
                     /translation="MTPFFELVILGELLVRENFSKLVAERKFIMKLKRFTLSLASLAS
                     FSLLVACSQRAQQVQQPVAQQVQQPAQQNTNTANAGGNQNQAAPVQNQPVAQPTDIDG
                     TYTGQDDGDRITLVVTGTTGTWTELESDGDQKVKQVTFDSANQRMIIGDDVKIYTVNG
                     NQIVVDDMDRDPSDQIVLTK"
     gene            20693..22225
                     /gene="cls"
                     /locus_tag="VQ862_000445"
     CDS             20693..22225
                     /gene="cls"
                     /locus_tag="VQ862_000445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000877342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HET3114846.1"
                     /translation="MKYRKFQLLMSKYGFSLSIMLLELCLVFGLFLYLGRMAPILWIT
                     VLILLSIITIISIVNRNTTPENKVTWLLVAFVPVFGPLLYLMFGERRLSKKEIKQLKK
                     LGSMHFQEANSQLLKEKLKESDKAAYGVIKSLLSMDTNADIYDQTASTFFPNGEAMWK
                     KMVEDLKKAEKFIFLEYYIIEEGLMWNRILDILEQKVAQGVEVKMLYDDIGCMATLTG
                     DYAHRLRQLGIEAHKFNKVIPRLTVAYNNRDHRKILIVDGQIAYTGGVNLADEYINHV
                     ERFGYWKDSGIRLDGLAVKALTRLFLTTWYINRGEISDFDQYHLENHSIPSDGLTIPY
                     GSGPKPIFRAQVGKKVYQSLINQATESVYITTPYLIIDYDLTETIKNAAMRGVDVRII
                     TPYIPDKKFIQLVTRGAYPDLLSAGVRIYEYSPGFIHSKQMLVDEDFAVVGTINLDYR
                     SLVHHYENAVLLYKTPSIREIARDFRNIFADSQEVYPHSIKTSWYQKLVKEIAQLFAP
                     IL"
     gene            22303..22446
                     /locus_tag="VQ862_000446"
     CDS             22303..22446
                     /locus_tag="VQ862_000446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000956126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3114847.1"
                     /translation="MLTKEEVNDMIEFKQTHLHRFREIETFVKLCKKSLKQPSQADNP
                     RTF"
     gene            22483..24021
                     /locus_tag="VQ862_000447"
     CDS             22483..24021
                     /locus_tag="VQ862_000447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="damage-inducible protein CinA"
                     /protein_id="HET3114848.1"
                     /translation="MSVYGRVEEVHKENREPLEYQIEQESHHRESSRLPLVKILLWST
                     LVTGITLGVPLLLDLMSAQEVQDFYAGWALHQTGKIYSDYYGSQGLLYYLLTYVSQGG
                     FFFAIFEWLALVAGGFFLFRSADTLTEQGDQAGHLVTIFYMLVTGLAFGGGYATLLAL
                     PFLFAAFSLVAAYLSNPSHDKGFVRIGLALAGGFFFAPLSSLLFIAVVGLGLLVFNLG
                     HRRFAHGFYQFLAVALGFSLVFYPTAYYSAATGSFGDAISGIRYPIDSIRFDFTSKIL
                     ENMFFYGLLSLGLGFVVCIFLGLFQSKPFKLYVISVPASLVVILGLILLFFSQEPLHA
                     SYLMVVFPVFLLLLVTNIKSQQRGRSARRSRRETPVSLWSRFFKGNLYLLVFGFVYLL
                     SVPFLMKFVLYPVPYQERNRLADLVKEETNTEDAIYAWDDTATLYRKSERLSPSAILS
                     PLHYTATEENRNKLLNDLKEKQPKVIVVNDKVVVWSEVETLLKENYQQVKTDYSEFKV
                     YKIK"
     gene            24141..26348
                     /gene="nrdD"
                     /locus_tag="VQ862_000448"
     CDS             24141..26348
                     /gene="nrdD"
                     /locus_tag="VQ862_000448"
                     /EC_number="1.17.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004239081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase"
                     /protein_id="HET3114849.1"
                     /translation="MIALEEKITILPTLFVEKRDGRRVVFDVDKIDKALHKAADKVMD
                     VTPLVEKRLNDLTERIITEIHSRFPQGIKIYEIQNIVEHELLEAKEYALAEEYITYRT
                     QRDFERSKATDINFSIHKLLNKDQTVVNENANKDSDVFNTQRDLTAGIVGKSIGLQML
                     PKHVANAHQKGDIHYHDLDYSPYTPMTNCCLIDFKGMLENGFKIGNAEVESPKSIQTA
                     TAQISQIIANVASSQYGGCSADRIDEILAPYAEKNYQKHLKDAEEWVLPEKREDYAWK
                     KTQKDIYDAMQSLEYEINTLFTSNGQTPFTSLGFGLGTSRFEREIQKAILNIRIKGLG
                     SEHRTAIFPKLIFTLKRGLNLEEGTPNYDIKQLALECATKRMYPDVLSYDKIVDLTGS
                     FKVPMGCRSFLQGWKDENGVEVNSGRMNLGVVTVNLPRIALESEGDMNKFWEIFNERM
                     NIAEDALVYRVERTKEATPANAPILYQYGAFGHHLGKEESVDQLFKNRRATVSLGYIG
                     LYEVATVFFGNSWESNPDAKEFTLDIIHDMKRRVEEWSDQYGYHFSIYSTPSESLTDR
                     FCRLDIDKFGSIPDITDKEYYTNSFHYDVRKNPTPFEKLDFEKVYPEAGASGGFIHYC
                     EYPVLQQNPKALEAVWDYAYDRVGYLGTNTPIDRCYKCDFEGDFEPTERGFACPNCGN
                     SDPKTVDVVKRTCGYLGNPQARPMVNGRHKEIAARVKHMNGSTIKIAGHQVTN"
     gene            26360..26500
                     /locus_tag="VQ862_000449"
     CDS             26360..26500
                     /locus_tag="VQ862_000449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000521630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3114850.1"
                     /translation="MGKYQLDDKGRAQVTRYHEKHSKGGAGKKERLLSFREQFLNKNK
                     KK"
     gene            26544..27050
                     /locus_tag="VQ862_000450"
     CDS             26544..27050
                     /locus_tag="VQ862_000450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000423398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET3114851.1"
                     /translation="MELRRPRLADKKAVLDMMTEFEKFQSPHDGGFWDTENFVYEDWL
                     ESNQEQEMGINLPEGWVPAIQLVAFSEKGQAVGFLNLRLRLSNFLLEEGGHIGYSIRP
                     SERGKGYAKETLRQGLQVAKEKNIKKALVTCSVNNPASRAVILANGGIFEDARNGVER
                     YWIEVANE"
     gene            27043..27633
                     /gene="nrdG"
                     /locus_tag="VQ862_000451"
     CDS             27043..27633
                     /gene="nrdG"
                     /locus_tag="VQ862_000451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001064213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase
                     activating protein"
                     /protein_id="HET3114852.1"
                     /translation="MNNPKPQEWKSEELSQGRIIDYKAFNFVDGEGVRNSLYVAGCMF
                     HCEGCYNVATWSFNAGIPYTAELEEQIMADLGQPYVQGLTLLGGEPFLNTGILLPLVK
                     RIRKELSDKDIWSWTGYTWEEMMLETPDKLELLSLIDILVDGRYDRTKRNLMLQFRGS
                     SNQRIIDVQKSLKSGQVVIWDKLNDGKESYEQVKRE"
     gene            27630..28247
                     /locus_tag="VQ862_000452"
     CDS             27630..28247
                     /locus_tag="VQ862_000452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribulokinase"
                     /protein_id="HET3114853.1"
                     /translation="MKKKGLVDQLVSEIETGKVRTLGIYGHGASGKSTFAQELSQALD
                     STTVNLLETDPYITSGRYLVVPKDAPNQKVTASLPVAYELESLQRDIFALQAGMDVLT
                     IEEPWKASEVLSGAKPILIVEGMSVGFLPKELFEKTICFYTDEETELKRRLARDTTVR
                     NRDASFILASHQMRREQYLRYYKETESKADILVDQSEDKFDVKRT"
     gene            28502..28810
                     /gene="rpsJ"
                     /locus_tag="VQ862_000453"
     CDS             28502..28810
                     /gene="rpsJ"
                     /locus_tag="VQ862_000453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S10"
                     /protein_id="HET3114854.1"
                     /translation="MANKKIRIRLKAYEHRTLDTAAAKIVESATRTGAQVAGPIPLPT
                     ERSLYTIIRATHKYKDSREQFEMRTHKRLIDIVNPTQKTVDALMKLDLPSGVNVEIKL
                     "
     gene            29027..29653
                     /gene="rplC"
                     /locus_tag="VQ862_000454"
     CDS             29027..29653
                     /gene="rplC"
                     /locus_tag="VQ862_000454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L3"
                     /protein_id="HET3114855.1"
                     /translation="MTKGILGKKVGMTQIFTEAGELIPVTVIEATPNVVLQVKTVETD
                     GYNAIQVGFDDKREVLSNKPAKGHVAKANTAPKRFIREFKNVEGLEVGAEITVETFAA
                     GDVVDVTGTSKGKGFQGVIKRHGQSRGPMAHGSRYHRRPGSMGPVAPNRVFKGKNLAG
                     RMGGDRVTIQNLEVVQVVPEKNVILIKGNVPGAKKSLITIKSAVKAGK"
     gene            29678..30301
                     /gene="rplD"
                     /locus_tag="VQ862_000455"
     CDS             29678..30301
                     /gene="rplD"
                     /locus_tag="VQ862_000455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L4"
                     /protein_id="HET3114856.1"
                     /translation="MANVTLFDQTGKEAGQVVLSDAVFGIEPNESVVFDVIISQRASL
                     RQGTHAVKNRSAVSGGGRKPWRQKGTGRARQGSIRSPQWRGGGVVFGPTPRSYGYKLP
                     QKVRRLALKSVYSEKVAENKFVAVDALSFTAPKTAEFAKVLAALSIDSKVLVILEEGN
                     EFAALSARNLPNVKVATATTASVLDIANSDKLLVTQAAISKIEEVLA"
     gene            30301..30597
                     /locus_tag="VQ862_000456"
     CDS             30301..30597
                     /locus_tag="VQ862_000456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007518994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L23"
                     /protein_id="HET3114857.1"
                     /translation="MNLYDVIKKPVITESSMAQLEAGKYVFEVDTRAHKLLIKQAVEA
                     AFEGVKVANVNTINVKPKAKRVGRYTGFTNKTKKAIITLTADSKAIELFAAEAE"
     gene            30615..31448
                     /gene="rplB"
                     /locus_tag="VQ862_000457"
     CDS             30615..31448
                     /gene="rplB"
                     /locus_tag="VQ862_000457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019790357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L2"
                     /protein_id="HET3114858.1"
                     /translation="MGIRVYKPTTNGRRNMTSLDFAEITTSTPEKSLLVALKSKAGRN
                     NNGRITVRHQGGGHKRFYRLVDFKRNKDNVEAVVKTIEYDPNRSANIALVHYTDGVKA
                     YIIAPKGLEVGQRIVSGPEADIKVGNALPLANIPVGTLIHNIELKPGRGGELVRAAGA
                     SAQVLGSEGKYVLVRLQSGEVRMILGTCRATVGVVGNEQHGLVNLGKAGRSRWKGIRP
                     TVRGSVMNPNDHPHGGGEGKAPVGRKAPSTPWGKPALGLKTRNKKAKSDKLIVRRRNE
                     K"
     gene            31552..31833
                     /gene="rpsS"
                     /locus_tag="VQ862_000458"
     CDS             31552..31833
                     /gene="rpsS"
                     /locus_tag="VQ862_000458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000533767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S19"
                     /protein_id="HET3114859.1"
                     /translation="MGRSLKKGPFVDEHLMKKVEAQANDEKKKVIKTWSRRSTIFPSF
                     IGYTIAVYDGRKHVPVYIQEDMVGHKLGEFAPTRTYKGHAADDKKTRRK"
     gene            31845..32189
                     /gene="rplV"
                     /locus_tag="VQ862_000459"
     CDS             31845..32189
                     /gene="rplV"
                     /locus_tag="VQ862_000459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L22"
                     /protein_id="HET3114860.1"
                     /translation="MAEITSAKAMARTVRVSPRKSRLVLDNIRGKSVADAIAILTFTP
                     NKAAEIILKVLNSAVANAENNFGLDKANLVVSEAFANEGPTMKRFRPRAKGSASPINK
                     RTAHITVAVAEK"
     gene            32202..32855
                     /gene="rpsC"
                     /locus_tag="VQ862_000460"
     CDS             32202..32855
                     /gene="rpsC"
                     /locus_tag="VQ862_000460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000529931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S3"
                     /protein_id="HET3114861.1"
                     /translation="MGQKVHPIGMRVGIIRDWDAKWYAEKEYADYLHEDLAIRKFVQK
                     ELADAAVSTIEIERAVNKVNVSLHTAKPGMVIGKGGANVDALRAKLNKLTGKQVHINI
                     IEIKQPDLDAHLVGEGIARQLEQRVAFRRAQKQAIQRAMRAGAKGIKTQVSGRLNGAD
                     IARAEGYSEGTVPLHTLRADIDYAWEEADTTYGKLGVKVWIYRGEVLPARKNTKGGK"
     gene            32859..33272
                     /gene="rplP"
                     /locus_tag="VQ862_000461"
     CDS             32859..33272
                     /gene="rplP"
                     /locus_tag="VQ862_000461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003029477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L16"
                     /protein_id="HET3114862.1"
                     /translation="MLVPKRVKHRREFRGKMRGEAKGGKEVAFGEYGLQATTSHWITN
                     RQIEAARIAMTRYMKRGGKVWIKIFPHKSYTAKAIGVRMGSGKGAPEGWVAPVKRGKV
                     MFEIAGVSEEIAREALRLASHKLPVKCKFVKREAE"
     gene            33282..33488
                     /locus_tag="VQ862_000462"
     CDS             33282..33488
                     /locus_tag="VQ862_000462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006739716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L29"
                     /protein_id="HET3114863.1"
                     /translation="MKLNEVKEFVKELRGLSQEELAKRENELKKELFELRFQAATGQL
                     EQTARLKEVKKQIARIKTVQSEAK"
     gene            33513..33773
                     /gene="rpsQ"
                     /locus_tag="VQ862_000463"
     CDS             33513..33773
                     /gene="rpsQ"
                     /locus_tag="VQ862_000463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006738952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S17"
                     /protein_id="HET3114864.1"
                     /translation="MERNNRKVLVGRVVSDKMDKTITVVVETKRNHPVYGKRINYSKK
                     YKAHDENNVAKEGDIVRIMETRPLSATKRFRLVEVVEEAVII"
     gene            33799..34167
                     /gene="rplN"
                     /locus_tag="VQ862_000464"
     CDS             33799..34167
                     /gene="rplN"
                     /locus_tag="VQ862_000464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012727667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L14"
                     /protein_id="HET3114865.1"
                     /translation="MIQTETRLKVADNSGAREILTIKVLGGSGRKFANIGDVIVASVK
                     QATPGGAVKKGDVVKAVIVRTKSGARRADGSYIKFDENAAVIIREDKTPRGTRIFGPV
                     ARELREGGFMKIVSLAPEVL"
     gene            34245..34550
                     /gene="rplX"
                     /locus_tag="VQ862_000465"
     CDS             34245..34550
                     /gene="rplX"
                     /locus_tag="VQ862_000465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011921687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L24"
                     /protein_id="HET3114866.1"
                     /translation="MFVKKGDKVRVIAGKDKGTEAVVLTALPKVNKVIVEGVNIVKKH
                     QRPTNELPQGGIIEKEAAIHVSNVQVLDKNGVAGRVGYKFVDGKKVRYNKKSGEVLD"
     gene            34574..35116
                     /gene="rplE"
                     /locus_tag="VQ862_000466"
     CDS             34574..35116
                     /gene="rplE"
                     /locus_tag="VQ862_000466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L5"
                     /protein_id="HET3114867.1"
                     /translation="MANRLKEKYLNEVVPALTEQFNYSSVMAVPKVDKIVLNMGVGEA
                     VSNAKSLEKAAEELALISGQKPLITKAKKSIAGFRLREGVAIGAKVTLRGERMYEFLD
                     KLVSVSLPRVRDFHGVPTKSFDGRGNYTLGVKEQLIFPEINFDDVDKTRGLDIVIVTT
                     ANTDEESRALLTGLGMPFAK"
     gene            35134..35403
                     /gene="rpsN"
                     /locus_tag="VQ862_000467"
     CDS             35134..35403
                     /gene="rpsN"
                     /locus_tag="VQ862_000467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006738440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HET3114868.1"
                     /translation="MAKKSMVAREAKRQKIVDRYAEKRAALKAAGDYEGLSKLPRNAS
                     PTRLHNRCRVTGRPHSVYRKFGLSRIAFRELAHKGQIPGVTKASW"
     gene            35688..36086
                     /gene="rpsH"
                     /locus_tag="VQ862_000468"
     CDS             35688..36086
                     /gene="rpsH"
                     /locus_tag="VQ862_000468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009754342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S8"
                     /protein_id="HET3114869.1"
                     /translation="MVMTDPIADFLTRIRNANQAKHEVLEVPASNIKKGIAEILKREG
                     FVKNVEIIEDDKQGVIRVFLKYGPNGEKVITNLKRVSKPGLRVYKKREDLPKVLNGLG
                     IAILSTSEGLLTDKEARQKNVGGEVIAYVW"
     gene            36278..36814
                     /gene="rplF"
                     /locus_tag="VQ862_000469"
     CDS             36278..36814
                     /gene="rplF"
                     /locus_tag="VQ862_000469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L6"
                     /protein_id="HET3114870.1"
                     /translation="MSRIGNKVIVLPAGVELANNDNVVTVKGPKGELTREFSKDIEIR
                     VEGTEVTLHRPNDSKEMKTIHGTTRALLNNMVVGVSEGFKKELEMRGVGYRAQLQGSK
                     LVLAVGKSHPDEVEAPEGITFELPNPTTIVVSGISKEVVGQTAAYVRSLRSPEPYKGK
                     GIRYVGEFVRRKEGKTGK"
     gene            36898..37254
                     /gene="rplR"
                     /locus_tag="VQ862_000470"
     CDS             36898..37254
                     /gene="rplR"
                     /locus_tag="VQ862_000470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018374469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L18"
                     /protein_id="HET3114871.1"
                     /translation="MISKPDKNKLRQKRHRRVRGKLSGTADRPRLNVFRSNTGIYAQV
                     IDDVAGVTLASASTLDKEVSKGTKTEQAVAVGKLVAERANAKGISEVVFDRGGYLYHG
                     RVKALADAARENGLKF"
     gene            37272..37766
                     /gene="rpsE"
                     /locus_tag="VQ862_000471"
     CDS             37272..37766
                     /gene="rpsE"
                     /locus_tag="VQ862_000471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S5"
                     /protein_id="HET3114872.1"
                     /translation="MAFKDNAVELEERVVAVNRVTKVVKGGRRLRFAALVVVGDHNGR
                     VGFGTGKAQEVPEAIRKAVDDAKKNLIEVPMVGTTIPHEVLSEFGGAKVLLKPAVEGS
                     GVAAGGAVRAVVELAGVADITSKSLGSNTPINIVRATVEGLKQLKRAEEIAALRGISV
                     SDLA"
     gene            37738..37962
                     /gene="rpmD"
                     /locus_tag="VQ862_000472"
     CDS             37738..37962
                     /gene="rpmD"
                     /locus_tag="VQ862_000472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012386624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L30"
                     /protein_id="HET3114873.1"
                     /translation="MVFQFLIWHKKGDKMAQIKITLTKSPIGRIPSQRKTVVALGLGK
                     LNSSVIKEDNAAIRGMITAVSHLVTVEEVN"
     gene            38107..38547
                     /gene="rplO"
                     /locus_tag="VQ862_000473"
     CDS             38107..38547
                     /gene="rplO"
                     /locus_tag="VQ862_000473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004225266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L15"
                     /protein_id="HET3114874.1"
                     /translation="MKLHELKPAEGSRKVRNRVGRGTSSGNGKTSGRGQKGQKARSGG
                     GVRLGFEGGQTPLFRRLPKRGFTNINAKEYAIVNLDQLNVFEDGAEVTPVVLIEAGIV
                     KAEKSGIKILGNGELTKKLTVKAAKFSKSAEEAITAKGGSVEVI"
     gene            38560..39870
                     /gene="secY"
                     /locus_tag="VQ862_000474"
     CDS             38560..39870
                     /gene="secY"
                     /locus_tag="VQ862_000474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecY"
                     /protein_id="HET3114875.1"
                     /translation="MFFKLLREALKVKQVRSKILFTIFIVLVFRIGTSITVPGVNANS
                     LNALSGLSFLNMLSLVSGNALKNFSIFALGVSPYITASIVVQLLQMDILPKFVEWGKQ
                     GEVGRRKLNQATRYIALVLAFVQSIGITAGFNTLAGAQLIKTALTPQVFLTIGIILTA
                     GSMIVTWLGEQITDKGYGNGVSMIIFAGIVSSIPEMIQGIYVDYFVNVPSSRITSSII
                     FVIILIITVLLIIYFTTYVQQAEYKIPIQYTKVAQGAPSSSYLPLKVNPAGVIPVIFA
                     SSITAAPAAILQFLSATGHDWAWVRVAQEMLATTSPTGIAMYALLIILFTFFYTFVQI
                     NPEKAAESLQKSGAYIHGVRPGKGTEEYMSKLLRRLATVGSLFLGVISILPIAAKDVF
                     GLSDVVAFGGTSLLIIISTGIEGIKQLEGYLLKRKYVGFMDRTE"
     gene            40021..40659
                     /locus_tag="VQ862_000475"
     CDS             40021..40659
                     /locus_tag="VQ862_000475"
                     /EC_number="2.7.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001050429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylate kinase"
                     /protein_id="HET3114876.1"
                     /translation="MNLLIMGLPGAGKGTQAAKIVEQFHVAHISTGDMFRAAMANQTE
                     MGVLAKSYIDKGELVPDEVTNGIVKERLSQDDIKETGFLLDGYPRTIEQAHALDKTLA
                     ELGIELEGIINIEVNPDSLLERLSGRIIHRVTGETFHKVFNPPVDYKEEDYYQREDDK
                     PETVKRRLDVNIAQGEPIIAHYRAKGLVHDIEGNQDINDVFSDIEKVLTNLK"
     gene            40776..40994
                     /gene="infA"
                     /locus_tag="VQ862_000476"
     CDS             40776..40994
                     /gene="infA"
                     /locus_tag="VQ862_000476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003130554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-1"
                     /protein_id="HET3114877.1"
                     /translation="MAKDDVIEVEGKVVDTMPNAMFTVELENGHQILATVSGKIRKNY
                     IRILAGDRVTVEMSPYDLTRGRITYRFK"
     gene            41019..41135
                     /gene="rpmJ"
                     /locus_tag="VQ862_000477"
     CDS             41019..41135
                     /gene="rpmJ"
                     /locus_tag="VQ862_000477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L36"
                     /protein_id="HET3114878.1"
                     /translation="MKVRPSVKPICEYCKVIRRNGRVMVICPANPKHKQRQG"
     gene            41153..41518
                     /gene="rpsM"
                     /locus_tag="VQ862_000478"
     CDS             41153..41518
                     /gene="rpsM"
                     /locus_tag="VQ862_000478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S13"
                     /protein_id="HET3114879.1"
                     /translation="MARIAGVDIPNDKRVVISLTYVYGIGLATSKKILAAAGISEDVR
                     VRDLTSDQEDAIRREVDAIKVEGDLRREVNLNIKRLMEIGSYRGIRHRRGLPVRGQNT
                     KNNARTRKGKAVAIAGKKK"
     gene            41536..41919
                     /gene="rpsK"
                     /locus_tag="VQ862_000479"
     CDS             41536..41919
                     /gene="rpsK"
                     /locus_tag="VQ862_000479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003130556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S11"
                     /protein_id="HET3114880.1"
                     /translation="MAKPTRKRRVKKNIESGIAHIHATFNNTIVMITDVHGNAIAWSS
                     AGALGFKGSRKSTPFAAQMASEAAAKSAQEHGLKSVEVTVKGPGSGRESAIRALAAAG
                     LEVTAIRDVTPVPHNGARPPKRRRV"
     gene            41962..42897
                     /locus_tag="VQ862_000480"
     CDS             41962..42897
                     /locus_tag="VQ862_000480"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000568977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit alpha"
                     /protein_id="HET3114881.1"
                     /translation="MIEFEKPNITKIDENKDYGKFVIEPLERGYGTTLGNSLRRVLLA
                     SLPGAAVTSINIDGVLHEFDTVPGVREDVMQIILNIKGIAVKSYVEDEKIIELDVEGP
                     AEVTAGDILTDSDIEIVNPDHYLFTIGEGSSLKATMTVNSGRGYVPADENKKDNAPVG
                     TLAVDSIYTPVTKVNYQVEPARVGSNDGFDKLTLEILTNGTIIPEDALGLSARILTEH
                     LDLFTNLTEIAKSTEVMKEADTESDDRILDRTIEELDLSVRSYNCLKRAGINTVHDLT
                     EKSEAEMMKVRNLGRKSLEEVKLKLIDLGLGLKDK"
     gene            42909..43295
                     /gene="rplQ"
                     /locus_tag="VQ862_000481"
     CDS             42909..43295
                     /gene="rplQ"
                     /locus_tag="VQ862_000481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002887523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L17"
                     /protein_id="HET3114882.1"
                     /translation="MAYRKLGRTSSQRKAMLRDLTTDLLINESIVTTEARAKEIRKTV
                     EKMITLGKRGDLHARRQAAAFVRNEIASENYDEATDKYTSTTALQKLFSEIAPRYAER
                     NGGYTRILKTEPRRGDAAPMAIIELV"
     gene            43560..43826
                     /locus_tag="VQ862_000482"
     CDS             43560..43826
                     /locus_tag="VQ862_000482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002905356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACT domain-containing protein"
                     /protein_id="HET3114883.1"
                     /translation="MKAIITVVGKDKSGIVAGVSGKIAELGLNIDDISQTVLDEYFTM
                     MAVVSSDEKQDFTYLRNEFEAFGQTLNVKINIQSAAIFEAMYNI"
     gene            43836..45173
                     /locus_tag="VQ862_000483"
     CDS             43836..45173
                     /locus_tag="VQ862_000483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018166727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PFL family protein"
                     /protein_id="HET3114884.1"
                     /translation="MDIRQVTETIAMIEEQNFDIRTITMGISLLDCIDPDINRAAEKI
                     YQKITTKAANLVAVGDEIAAELGIPIVNKRVSVTPISLIGAATDATDYVVLAKALDKV
                     AKEIGVDFIGGFSALVQKGYQKGDEILINSIPRALAETDKVCSSVNIGSTKSGINMTA
                     VADMGRIIKETANLSDMGVAKLVVFANAVEDNPFMAGAFHGVGEADVIINVGVSGPGV
                     VKRALEKVRGQSFDVVAETVKKTAFKITRIGQLVGQMASERLGVEFGIVDLSLAPTPA
                     VGDSVARVLEEMGLETVGTHGTTAALALLNDQVKKGGVMACNQVGGLSGAFIPVSEDE
                     GMIAAVQNGSLNLEKLEAMTAICSVGLDMIAIPEDTPAETIAAMIADEAAIGVINMKT
                     TAVRIIPKGREGDMIEFGGLLGTAPVMKVNGASSVDFISRGGQIPAPIHSFKN"
     gene            45417..46109
                     /locus_tag="VQ862_000484"
     CDS             45417..46109
                     /locus_tag="VQ862_000484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HET3114885.1"
                     /translation="MVKVRLYLVRHGKTMFNTIGRAQGWSDTPLTAEGERGIQELGIG
                     LRESDLQFERAYSSDSGRTIQTMGIILEELGLQGKIPYRMDKRIREWCFGSFDGAYDG
                     DLFMGIIPRIFNVDHVHQLSYAELAEGLVEVDTAGWAEGWEKLSGRIKEGFEIIAKEM
                     EDQGGGNALVVSHGMTIGTIVYLINGMHPHGLDNGSVTILEYEDGQFRVEVVGDRSYR
                     ELGREKMEEGSI"
     gene            complement(46212..47857)
                     /locus_tag="VQ862_000485"
                     /pseudo
     CDS             complement(46212..47857)
                     /locus_tag="VQ862_000485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520796.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
     gene            complement(47847..48470)
                     /locus_tag="VQ862_000486"
     CDS             complement(47847..48470)
                     /locus_tag="VQ862_000486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001843667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3114886.1"
                     /translation="MDEPLSNLEAKLRLDMRQAIREIQHEVGITTVYVTHDQEEAMAI
                     SDQIAVMKDGVIQQIGRPKELYHKPANEFVATFIGRTNIIPANLEKRSDGAYIVFSDG
                     YALRMPALDQVEEQAIHVSIRPEEFIKDESGDIEGTISDSVYLGLNTEYFIETGFASK
                     IQVSEESTFEEELQKGNRIRLRINTQKLNIFSADGSQNLIKGVNHGM"
     gene            complement(48456..48578)
                     /locus_tag="VQ862_000487"
                     /pseudo
     CDS             complement(48456..48578)
                     /locus_tag="VQ862_000487"
                     /inference="COORDINATES: protein motif:HMM:NF012235.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
     gene            complement(48555..48925)
                     /locus_tag="VQ862_000488"
                     /pseudo
     CDS             complement(48555..48925)
                     /locus_tag="VQ862_000488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001289359.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
     gene            complement(48938..50059)
                     /locus_tag="VQ862_000489"
                     /pseudo
     CDS             complement(48938..50059)
                     /locus_tag="VQ862_000489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931989.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
     gene            complement(50645..51421)
                     /locus_tag="VQ862_000490"
     CDS             complement(50645..51421)
                     /locus_tag="VQ862_000490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000406168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl-radical enzyme activating protein"
                     /protein_id="HET3114887.1"
                     /translation="MEISKGIIFNIQHFSIHDGPGIRTTVFLKGCPLRCPWCSNPESQ
                     RMKPEKMKDAQREKFTLVGEEKTVEEIITEVLKDKEFYEESGGGLTLSGGEIFAQFEF
                     AKAILKSAKEHHIHTAIETTAFVDHEKFIDLIQYVDFIYTDLKHYNSIKHKKVTGVFN
                     QMIIKNIHYAFSQNKTIVLRIPVIPNFNNSLEDAEKFATLFNSLNIDQVQLLPFHQFG
                     ENKYRLLNRKYEMDGVNALHPEDLIDYQKVFLNHHINCYF"
     gene            51543..52289
                     /locus_tag="VQ862_000491"
     CDS             51543..52289
                     /locus_tag="VQ862_000491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000824973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HET3114888.1"
                     /translation="MKRLEQIIKLVSEYEKIDVNTLSEKLNVSKVTIRKDLDKLESKG
                     LLHREHGYAVLNSGDDLNVRLSINYEIKRKIVQEAVKLVSDNETIMIESGSTCALLAE
                     EICKQKRNVTIVTNSFFIANFVRAYDSCRIIVLGGEFQKDSQVTVGPLLKEMIQTFHV
                     RQAFVGTDGYDKEMGFTGKDLMRSEVVQYISAASDKVIVLTDSSKFDKRGTVRRFALS
                     QVYEVITDEKLSKQNIATLENAGIMVKVVS"
     gene            52302..53282
                     /locus_tag="VQ862_000492"
     CDS             52302..53282
                     /locus_tag="VQ862_000492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001070834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-binding transcriptional regulator"
                     /protein_id="HET3114889.1"
                     /translation="MNQDRNKLLSKIAYLYYIENLNQSQIAAKLGIYRTSISRMLTEA
                     RNAGIVKIEIENFDTNMFKLENYVKEKYGLESLEIIPNEFDDNPTILSERISQVAAGV
                     LRNLIDDNMKIGFSWGKSLSNLVDLIHSKSVRNVHFYPLAGGPSHIHAKYHVNTLIYE
                     MSRKFHGECTFMNATIVQENKLLADGILQSRYFENLKNSWKDLDIAVVGIGDFSNKGK
                     HQWLDMLTEDDFKELTKVKTVGEICCRFFDSKGKEVYENLQERTIAISLEDLKNIPQS
                     LAVAYGDTKVSSILSVLRANLVNHLITDKNTILKVLEEDGDLTFREILGE"
     gene            53477..53797
                     /locus_tag="VQ862_000493"
     CDS             53477..53797
                     /locus_tag="VQ862_000493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000402908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HET3114890.1"
                     /translation="MEIIVPDQIIMGLILYAGDAKQHIYKALDYIKNGTCERCEEEIQ
                     LADAALLEAHNLQTKFLAQEASGTKTEITALFVHSQDHLMTSMTEINLIKEIISLRKE
                     LHKK"
     gene            53843..54151
                     /locus_tag="VQ862_000494"
     CDS             53843..54151
                     /locus_tag="VQ862_000494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000238716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HET3114891.1"
                     /translation="MVKIGLFCAAGFSTGMLVNNMKIAAQASGVEAEIEAFSQSKLAD
                     YAPNIDVALLGPQVAYTLDKSKEICDKCDVPIAVIPMMDYGMLDGKKVLDLALSLISG
                     "
     gene            54168..55466
                     /locus_tag="VQ862_000495"
     CDS             54168..55466
                     /locus_tag="VQ862_000495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000041357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HET3114892.1"
                     /translation="MSKMDVQKIIAPMMKFVNMRGIIALKDGMLAILPLTVVGSLFLI
                     MGQLPFEGLNKSIASVFGANWTEPFMQVYSGTFAIMGLISCFSIAYSYAKNSGVEALP
                     AGVLSVSAFFILLRSSYIPKQGEAIGDAISKVWFGGQGIIGAIIIGLVVGSIYTFFIK
                     RKIVIKMPEQVPQAIAKQFEAMIPAFVIFLSSMIVYILAKSLTNGGTFIEMIYSAIQV
                     PLQGLTGSLYGAIGIAFFISFLWWFGVHGQSVVNGVVTALLLSNLDANKAMLASANLS
                     LENGAHIVTQQFLDSFLILSGSGITFGLVVAMLFAAKSKQYQALGKVAAFPAIFNVNE
                     PVVFGFPIVMNPVMFVPFILVPVLAAVIVYGAIATGFMQPFSGVTLPWSTPAILSGFL
                     VGGWQGVVTQLLVLVISTVVYFPFFKIQDRLAYQNEIKQS"
     gene            55617..58055
                     /locus_tag="VQ862_000496"
     CDS             55617..58055
                     /locus_tag="VQ862_000496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl radical protein"
                     /protein_id="HET3114893.1"
                     /translation="MVNTEVARTTIKTEYFGSLTERMNKYREDVLNKKPYIDAERAVL
                     ATRAYERYKEQPNVLKRAYMLKEILENMSIYIEEESMIAGNQASSNKDAPIFPEYTLE
                     FVLNELDLFEKRDGDVFYITEETKEQLRSIAPFWENNNLRARAGALLPEEVSVYMETG
                     FFGMEGKMNSGDAHLAVNYQKLLQFGLRGFEERARKAKVALDLTDPASIDKYHFYDSI
                     FIVIDAIKVYAKRFVALAKSLAENANPKRKKELLEIADICSRVPYEPATTFAEAIQSV
                     WFIQCILQIESNGHSLSYGRFDQYMYPYMKADLESGKETEDSIVERLTNLWIKTITIN
                     KVRSQSHTFSSAGSPLYQNVTIGGQTRDKKDAVNPLSYLVLKSVAQTHLPQPNLTVRY
                     HAGLDARFMNECIEVMKLGFGMPAFNNDEIIIPSFIAKGVLEDDAYDYSAIGCVETAV
                     PGKWGYRCTGMSYMNFPKVLLITMNDGIDPASGKRFAPSFGHFKDMKNFSELENAWDK
                     TLRYLTRMSVIVENSIDLSLEREVPDILCSALTDDCIGRGKHLKEGGAVYDYISGLQV
                     GIANLSDSLAAIKKLVFEEERISPSQLWHALETDYAGEEGKVIQEMLIHDAPKYGNDD
                     DYADKLVTAAYDIYVDEIAKYPNTRYGRGPIGGIRYSGTSSISANVGQGRGTLATPDG
                     RNAGTPLAEGCSPSHNMDQHGPTSVLKSVSKLPTDEIVGGVLLNQKVNPQTLAKEEDK
                     LKLIALLRTFFNRLHGYHIQYNVVSRETLIDAQKHPEKHRDLIVRVAGYSAFFNVLSK
                     ATQDDIIGRTEHTL"
     gene            58074..58742
                     /locus_tag="VQ862_000497"
     CDS             58074..58742
                     /locus_tag="VQ862_000497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000395441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="HET3114894.1"
                     /translation="MEFMLDTLNLDEIKKWSEILPLAGVTSNPTIAKREGSINFFERI
                     KDVRELIGSTPSIHVQVISQDFEGILKDAHEIRRQAGDDIFIKVPVTPAGLRAIKVLK
                     KEGYHITATAIYTVIQGLLAIEVGADYLAPYYNRMENLNIDSNSVIRQLALAIDRQNS
                     PSKILAASFKNVAQVNNALAAGAHAVTAGADVFESAFAMPSIQKAVDDFSDDWFVTQN
                     SRSI"
     gene            58760..59848
                     /locus_tag="VQ862_000498"
     CDS             58760..59848
                     /locus_tag="VQ862_000498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol dehydrogenase"
                     /protein_id="HET3114895.1"
                     /translation="MRIFASPSRYIQGENALFENAKSILDLGNYPILLCDQLVYDIVG
                     KRFEDYLHRYGFHIVLALFNGEASDNEINRVVALAEKENCDSIIGLGGGKTIDSAKAI
                     ADLIEKPVIIAPTIASTDAPVSALSVIYTDEGAFDHYLFYSKNPDLVLVDTKVISQAP
                     KRLLASGIADGLATWVEARAVMQANGKTMLGQQQTLAGVAIAKKCEETLFADGLQAMA
                     ACEAKVVTPALENIVEANTLLSGLGFESGGLAAAHAIHNGFTALTGDIHHLTHGEKVA
                     YGTLVQLLLENRPKEELDKYIEFYKKIGMPTTLKEMHLDQVGYDDLIKVGKQATMEGE
                     TIHQMPFKISPSDVAQAIIAVDAYVNSK"
BASE COUNT        18330 a        10816 c        12966 g        17811 t
ORIGIN      
        1 atttcactat agtaaggtgc agcaggataa agaaaaaccg agaagtttct ttctcggatt
       61 tgcttattat gaggttccta ttttctatgc tccaagagtt gattgatgtg atctactttt
      121 ttagcctctc ttttatagag aatagcccag atgatgagat agacaatcgc aaactcgata
      181 atgagctgga ggtagaaaat ccagtggaaa gggaaccaac cagcaagagt tgctagtggg
      241 acaaagccag ccagcataag gaagaaatga gtcagagtgg cacgaagcat gctccagtca
      301 cggctgaata agcggttgcc aaagttgaag agcataccga tggctgccca gataagtgtg
      361 cagtagagca agaccagggc accgtgaacc tgatgctgat ccatcacttg gccgatgaga
      421 gagtagggat ttagtggtgc gtaggtattt ggtgcataaa tgagtgaaaa gaggatggag
      481 aggatgaggc cgataagaac accggcagct gcatcgtgaa atacttgttt tttcatagtt
      541 ctaatttctc cttgatggtt tttagataac ggcgtgaaga gtaggtgaag ctttcgtttt
      601 tcaagaaaat ttctaccaga ccgtttggcg tgagcttgag gtgagagatg gaatcgatat
      661 tgatgatttc tgattgggaa atttggataa aattggttgg caagagttta agaacctgat
      721 agagtcgcaa atcaatgctg taggtctgac tcgcggtttc tgctagaacc ttccgattct
      781 cgatatagaa gcgctgaatc ttgccaatct caactagata gacctgatca tcgattttcc
      841 ctttgatttt ttctctttgg tccagatttt ctgcgaactc gatgactttc tggactttat
      901 ctgtcggctg aggtgcttgg acaatcagct tttcctcctc gtaagtctca ctaatctgta
      961 gttctacttt catagttttc tctccttttc agttatacaa ggttgtgatc acttcctgta
     1021 tatccttatt aaacactatt ttatagccca tggcaaggaa ccttgtctat gtggagggat
     1081 tgggctccta tgtggtggag cttttctgtt ctttctgaaa tatggtataa tagcactaat
     1141 taatttctag gaaaatagat acagaaaggg gctgaaagat gtctcatatt attgaattgc
     1201 cagagatgct ggcaaaccaa atcgcagctg gggaggtcat tgaacgtcct gccagtgtgg
     1261 ttaaagagtt ggtagaaaat gccattgacg cgggctctag tcagattatc attgagattg
     1321 aggaagctgg tctcaagaag gttcaaatca cggataacgg tcatggaatt gcccacgatg
     1381 aggtggagtt ggccctgcgt cgccatgcga ccagtaagat aaaaaatcaa gcagatctct
     1441 ttcggattcg gacgcttggt tttcgtggtg aagccttgcc ttctattgcg tctgttagtg
     1501 tcttgactct gttaacggcg gtggatggtg ctagtcatgg aaccaagtta gtcgcgcgtg
     1561 ggggtgaagt tgaggaagtc atcccagcga ctagtcctgt gggaaccaag gtttgtgtgg
     1621 aggatctctt tttcaacacg cctgcccgtc tcaagtatat gaagagccag caagcggagt
     1681 tgtctcatat cattgatatt gtcaaccgtc tgggcttggc ccatcctgag atttctttta
     1741 gcttgattag tgatggcaag gaaatgacgc ggacagcagg gactggtcaa ttgcgccaag
     1801 caatcgcagg gatttacggt ttggtcagtg ccaagaagat gattgaaatt gagaactctg
     1861 acctagattt cgaaatttca ggttttgtgt ccttgcctga gttgactcgg gctaaccgca
     1921 attatatcag cctcttcatc aatggtcgtt atatcaagaa cttcctgctc aatcgtgcta
     1981 ttttggatgg tttcggaagc aagcttatgg ttggacgttt tccactggct gtcattcaca
     2041 tccatatcga cccttatcta gcggatgtca atgtgcatcc aactaagcaa gaggtgcgga
     2101 tttccaagga aaaagaactg atgaccctgg tttcagaagc tattgcaaat agtctcaagg
     2161 aacaaacctt gattccagat gccttggaaa atcttgccaa atcgaccgtg cgcaatcgtg
     2221 agaaggtgga tcaaactatt ctcccactca aagaaaatac gctctactat gagaaaactg
     2281 agccgtcaag acctagtcaa actgaagtag ctgattatca ggtagaattg actgatgaag
     2341 ggcaggattt gaccctgttt gccaaggaaa ccttggaccg attgaccaag ccagcaaaac
     2401 tgcattttgc agagagaaag cctgctaact acgaccagct agaccatcca gagttagatc
     2461 ttgctagcat cgataaggct tatgacaaac tggagcgaga agaagcatcc agcttcccag
     2521 agttggagtt tttcggacaa atgcacggga cttatctctt tgcccaaggg cgagatggac
     2581 tttacatcat agatcagcac gctgctcagg aacgggtcaa gtacgaggag taccgtgaaa
     2641 gcattggcaa tgttgaccag agccagcagc aactcctagt gccctatatc tttgaatttc
     2701 ctgcggatga tgccctgcgt ctcaaggaaa gaatgcctct cttagaggaa gtgggcgtct
     2761 ttctagcaga gtacggagaa aatcaattta ttctacgtga acatcctatt tggatggcag
     2821 aagaagagat tgaatcaggc atctatgaga tgtgcgacat gctccttttg accaaggaag
     2881 tttctatcaa gaaataccga gcagagttgg ctatcatgat gtcttgcaag cgatctatca
     2941 aggccaatca tcgtattgat gatcattcag ctagacaact cctctatcag ctttctcaat
     3001 gtgacaatcc ctataactgt cctcacggac gtcctgtttt ggtgcatttt accaagtcgg
     3061 atatggaaaa gatgttccga cgtattcagg aaaatcacac cagtctccgt gagttgggga
     3121 aatattaaaa gtataaaaaa gtctgggaaa aattttcaaa atcagaaaaa cgcataaaat
     3181 caggtgttca aaaaccttga ttttatgcgt tttatcatgg aaatagttac ttcatgtttt
     3241 cctaattctt ttcgaaactc tttttaaacc acgtcagttt tatcagtaat ctcaaaacag
     3301 tgttttgagc taattttgcc agttttgtct gtaacatcga agttgtgttt gaccactctg
     3361 cgactggttt cctagtttgc tctatgattt tcacagagta ttaaattgcg attttgccaa
     3421 gtttctttat tcgtctaaaa gtagagtctg ttctatgcgt ctaatgtacg aattaggttg
     3481 accatttcaa tagctccttg tgcacactca gaacccttat ttcctgcttt agtgccagct
     3541 cgttctatgg cttgttcaat tgtatctgtc gttagcacac caaacataac aggaatttcg
     3601 ctatttaaac tgatttgggc gattccctta gatacctcgc tacatacata atcataatga
     3661 cttgtattcc ctctaatgac agctcccaag cagataattg catcatattt tttacttttt
     3721 gccatttttg atgcaatcag tggtatttca aaagctcctg gaacccaggc tacctctata
     3781 tctttctcgt ttacattctc tcttttgaga ttatctagtg ctccagataa taattttgaa
     3841 gttataaatt cattaaatct cgctacaaca atacctattt taatattgtt tgctactaaa
     3901 ttaccttcat aagtgttcat ttatttttcc tccatattta aaatgtgacc cattcgattt
     3961 ttctttgttt ctaaataaaa actatcgtaa ggattggctt ctatttcgat tgatattcta
     4021 ctggaaatgg taattccata tttttctaac tgttcaacct tgtcaggatt atttgtcagt
     4081 aaatgaagtg actgaagtcc cagatcttta agcatttgtg ctccaatatg atattctctt
     4141 aaatcacctt caaagcctaa tgcaagattg gcatcaagcg tatccatgcc ttgatcttgt
     4201 aaatgatagg cttttaattt attgataagt ccaattcctc gtccctcctg tcgcaagtaa
     4261 agtaagacac ccgaaccatt ctcaacaatc attttcatag ctttatcgaa ttgctgtcca
     4321 caatcgcaac gtaaagagcc taaaacatct cctgttaaac attcggagtg gacccgacat
     4381 aatacattgg cttcatcctc tatgtttccc ataataagag caagatgatg ttccccattt
     4441 agtttatcta tatagctaat tgctttgaaa ttaccgtatc tagtaggcat attgacagtt
     4501 gaaactcgtt ctaccagctg atcatatact tttctatatt cttgtaattc tttgatggta
     4561 attagtggaa tgttgtgttt cttcgagaac tgaattaaat catctgttct catcattttg
     4621 ccatcatgat tcattatttc acaacatagg ccacactctt ttagtccagc taattttaat
     4681 aaatcaacag ttgcttctgt gtgtccattt ctttctagaa caccaccttt ttttgcaatt
     4741 aaaggaaaca tgtgtcctgg cctgcgaaaa tcagagggtg ttatatcttc agctacacac
     4801 atacgtgcgg tcagtcctct ttcctcggca gaaatacctg tggtcgtttc tttataatca
     4861 attgaaactg taaaagcagt cttatgatta tctgtattgt tttcaaccat aggtgaaagc
     4921 attaattgat tagctaaact ttcgctcata ggcatacaaa ttaatccttt ggcataagta
     4981 gccataaaat taacattttc tgttgtagct gcttgtgcag aacaaattaa gtctccttca
     5041 ttttctctat ccttgtcgtc tataacaaga acaagtcgtc ccttctgcaa tgcttctaat
     5101 gcttcttgta tttttcgata ttccattgac tgattatcct ttctgctaaa atccattttg
     5161 atataatagt tccttagata tttctgattt tggagagtta tccatcagtt tttgcacata
     5221 tttacctaag atatcatttt caagatttac tgtactcccg acttgtttac tcttaagaat
     5281 ggtttgttcc aaggtatgag ggataacaga tactgaaaag tttactttgg agactttagc
     5341 gacagtcaga ctaatgccgt caattgtaat agatcctttt tcaactatta aatctaaaat
     5401 ttctttttgt gtgttgattt gataccatac agcattatca tcttttttta ttgacgagat
     5461 ttttcctgta ccatcaatgt gtcctgtaac gacgtgaccc ccaagtcgac cgttgacaga
     5521 taaggctctt tctagattca cctcacttcc atgttttaat agagtaagag ctgttcgact
     5581 ccatgtttca ttcattacat caactgtaaa ggattgatga ttgaaatgag taactgtaag
     5641 acagatacca tttactgcta tactatcgcc taaatggata tccgttaata tttttgaggc
     5701 tttaattgat agtttacaat tacgagagtc tttctgtatt ctttcaactt ttccgatttc
     5761 ttcaattatt cctgtgaaca tggataaatc acttcacttt ctatgagata gtcatttcct
     5821 atttgagaaa atgcataagg tttcaatcta atagcgtcat ttggcaaaga aatgccttca
     5881 cctccgacag gaaacttggc actgcctcca aaaatttttg gtgcaatata tattttcagc
     5941 tcatcaacaa tttgttgttc caaagcactc caattcatta gactgccccc ttctagaact
     6001 aggctatcaa tctgcatgtt tcctagatgt tgcattaaac tcgataagtc tatatgattg
     6061 ccttttttct ttatggaaag tatttcacag ccatgatttt gatatagctt cattttattt
     6121 ttgttttcag aggaagtggc aatgtaagtt ttaatatcat ttgctgtttt tacgatttta
     6181 gaggtaagag gagttcgtaa atgtgtatcg catatgatac ggataggatt tttcccttcc
     6241 tccaatctac atgtcagcaa aggatcgtct tgaataacag tattgactcc caccataatt
     6301 gcactaacat ggtgtcgtaa ctgatgcaca tgctttcttg cttcttcttc agtaatccat
     6361 ttggattgat ttgttttagt ggctattttt ccatccattg acattgcata tttcataaaa
     6421 acatagggta catgctgggt aatatacttt ctaaaacttt ttattaagtt aagacactca
     6481 ttttctaaaa ttccaacagt aacttgaaga ttattttcct caagtatctt tactcctttt
     6541 ccagatacaa taggattaca gtctaggctt ccaatgacta ctcttgtaat accactatcg
     6601 attatagcat ctatacaggg aggtgttttc ccgaagtgac aacagggttc aagtgttaca
     6661 taaagcgtcg ctccgacagg ggattttcta cagtttttaa gagcatttct ctcagcatgt
     6721 gggccaccaa aaaactcatg ataaccttgt ccgataatgt gattatcttt tacaataatt
     6781 gcgccaacca taggattggg attgacgtaa ccagcccctt tttgtgccag ttttattgct
     6841 aatttcatat attttgaatc gctcatctca ctacctccaa aaaaatatac cttgaatagg
     6901 ggactactca aggcatacaa aagaaaactt atgcgattaa caaaaatgct ctgaaatgac
     6961 aagtaatcat ttcagagcac gcaaaaagca caaatatact tttatcttct ttcatccaga
     7021 ctatactgtc ggctttggaa tttcaccaaa tcatgccttt cggctcgtgg gctataccac
     7081 cggtagggaa ttgcaccctg ccctgaagat agttattcaa ttacagatga ttatagtact
     7141 taattttgaa tatgtcaaca gataaataca gattgttttt gatatactgt atttgtgata
     7201 atcgattctc gctcctcgga taaagaaaat atgatatact agataaacga aataagagag
     7261 aaggaacact atgtacgcat atttaaaagg aatcattacc aaaattactg ccaaatacat
     7321 tgttcttgaa accaatggta ttggttatat cctgcatgtg gccaatcctt atgcctattc
     7381 aggtcaggtt aatcaggagg atcagattta tgtgcatcag gttgtgcgtg aggacgccca
     7441 tttgctttat ggatttcgct cagaggatga gaaaaagctc tttcttagtc tgatttcggt
     7501 ctctgggatt ggtcctgtat cagctcttgc tattatcgct gctgatgaca atgctggctt
     7561 ggttcaagcc attgaaacca agaacatcac ctacttgacc aagttcccta aaattggcaa
     7621 gaaaacagcc cagcagatgg tgctggactt ggaaggcaag gtagtagttg caggagatga
     7681 ccttcctgcc aaggtcgcag tacaagcaag tgctgaaaac caagaattgg aagaagctat
     7741 ggaagccatg ttggctctgg gctacaaggc aacagagctc aagaaaatca agaaattctt
     7801 tgaaggaacg acagatacag ctgagaacta tatcaagtcg gcccttaaaa tgttggtcaa
     7861 ataggagcag agaatgacaa aacgttgttc gtgggtcaag atgaccaacc cgctctacat
     7921 cgcctatcat gatgaggagt ggggtcagcc cctccatgat gaccaagcat tgtttgagtt
     7981 gttgtgtatg gaaacctatc aggcaggcct gtcttgggaa acggtactca acaaacgcca
     8041 agctttccga gaagcctttc atagctatca aattcactca gtcgcagaga tgactgacac
     8101 tgaattggaa gccatgctgg agaatccagc tatcattcga aatagagcca agatttttgc
     8161 tacacgcgct aacgcccaag cctttctaca gttacaggca gagtacggct cttttgatgc
     8221 ctatctttgg tcttttgttg aggggaaaac tgtcgttaac gatgttcctg attatcgcca
     8281 agccccagct aaaacaccct tatctgagaa attagccaaa gatctcaaaa aacgaggctt
     8341 caagttcaca ggcccagtcg ccgtattgtc ttttctacag gctgcagggc tagttgatga
     8401 ccacgagaat gattgtgagt ggaaaggtct taaatgatgt ctaacaaaaa taagggaatt
     8461 ctgatttttg cgattctcta tacaatcctc tttgtgtttg atggcgttaa attgctggct
     8521 tctttaatgc catctgtcat tgcaaattat cttgtttatg tagttttagc tttatatggc
     8581 tccttcttgt tcaaggatag attgatccaa caatggaagg agattagaaa gactaaaaga
     8641 aaattcttct ttggcgtctt aacaggatgg ctctttctca ttctgatgac tgttgtcttt
     8701 gaatttgtat cagagatgtt gaagcagttt gtgggattag atggacaagg tctaaatcag
     8761 tctaatattc aaagtacctt tcaagaacaa ccactactga tagctgtttt tgcttgtgtc
     8821 attggacctc tggtagaaga attatttttc cgtcaggtct tattgcatta cttgcaggaa
     8881 cggttgccag gtttactaag cattattctg gtaggacttg tttttgctct gactcatatg
     8941 cacagtttgg ctctatcaga gtggattggt gcagttggtt acttaggtgg aggccttgcc
     9001 ttttctatta tttatgtgaa agaaaaagag aatatctact atcccctact tgttcacatg
     9061 ttaagcaaca gcctctcctt aatcatttta gctatcagta tagtaaaatg aaatgagaac
     9121 aggacaaatc gatttctaac aatgttttag aagtagaggt gtactattct agtttcaata
     9181 tactgtaata tgtgatgaaa atgccagtaa tgataccgag aaaaaagctg agaaactttt
     9241 cccagcttta tttgttatag tcaaagagaa tgacttgttc ctgtgcatct acatgagcat
     9301 ggaccccaaa gggtacaatt gctcttggag ttgcgtggcc gacattcaga ttatagacaa
     9361 tcgggatatt gctgtcaatg atatccaata gtgcctcttt atagtcgtca tggaaagttt
     9421 catccatagg ttttccgacc aagagtccat tgatgaccgc gaatatgcca gtgtccttta
     9481 aagttagcaa catttttttg aagtcttctg gcttaggctt ttcttcgctt gtttcgagca
     9541 agaggatttt cccttcccag tctgacaagt cagggaaaag tttgtatttt tggcagagtt
     9601 ccgtgctatc tgcgtatcga gagttgtcaa agatatcgta gagggattcg aggcaaccac
     9661 cgaggatttt cccctcgaac tgagcacttc cttgcaacaa gtcaaaacct gtatttgtat
     9721 gactgacacg aggtgttccc agggccgtgg gactaaaatc agttcgttcc tcataccaaa
     9781 cgtcactagg gcggatttct gaaattcttc ccgtcttaat caattcttta aagtagtgaa
     9841 ggctataggc tagcatttct ttgtctaatt cacaaatgtc tgctaaaaag gattgaccat
     9901 aaaaagtctt gattcctaat ttatgcaaca tgaggtggtt catggttgta tccgagaagc
     9961 caagaaaaat tttttgcttg ataacctttt ggagttggtc attttcaaaa agataaggta
    10021 gcaagcgata ggtatcgtct ccaccgatgg cacataggat catgtcgatg ctatcatcag
    10081 aaaaggcatg aatcaaatcc tctgcacgag cttcaggatg gtccttgata aagtctaatc
    10141 cttttaacga atgggacaaa aagatgggat tgagtcccag atccttgaga cgttggatac
    10201 ccaagtccac ttcgtgtttg acaaaatcct ctccgataat gccactagat aaactaacaa
    10261 taccaatagt agaaaccata tctcatcctc ctagaaatag attgagccta ttttatcaca
    10321 aaatataaga gaaagctatg tgggatttca gaagaatact tttaatactc ttcgaaaatc
    10381 tcttcaaacc acgtcagttt tatctgcaac ctcaaagctg tgctttgagc aacctgcagc
    10441 tagcttccta gtttgctctt tgattttcat tgaatataac tcaaaaaagt aagtgaaaaa
    10501 gcaaccgcac ctgcagttgc ttttatcgtt ttcttattct tgatagcgtg ttggtcctgc
    10561 acttgcacta cggatattca agcgtttctt gagatagaag cgaagggcta ggagggctgc
    10621 tccaataata gctagtggca atggatccag tactgggtta aggctagctg gtaggaagct
    10681 tgttgcaaag aagacaagca accaaaggaa catagaagct aggataacta gtacagattt
    10741 ccagaaaggt ggacgttgac tgcgatccat atctgatcca tagtattggt aaacaaagta
    10801 gtacatcaag tagaaggcaa atccaccaac cagtccaact aatagaagag taatcaatcc
    10861 atagccgaaa gcttggtctg ccgcaaagaa ggttgtgagg gcgctgacaa gggcaaagag
    10921 gctagtgatg aaaagagctg agtccataat catcagtttt gggtcatcat tttcttttgg
    10981 atgctctttt tcgtactgct ctttgacagt gaagctatga gcccaatgag ttggtgcgcc
    11041 gtatagggaa cgggcagttg tacctttaga ttgctcctca aggatttggg gaatgacttc
    11101 ctcaaaaata gtctggattt cagcgtctgt tttcccatct ttgatgaatt gttgggtagc
    11161 aatgtggaca aactcttggt ttttcttagt taatttttgt agatcaattt gagacatagg
    11221 aactcctctt agaaccattt tttatggatg agatagagag tgagcgagac actcatagca
    11281 aaggcgataa agacgattaa ccagaaggca tttggctctc cgtttagggg gatttcatta
    11341 tccttaaagt tcatcccgta ggcagaaaag accatggttg ggatggacat gacgatggtc
    11401 acaagggcca aggttttcat gatgttgttc tggttgttag aaatgataga ggcaaaggtc
    11461 tctgtcatag aatgcaagac gtttccataa atatctgcca tctcgatggc ctgttgggtt
    11521 tcaatcaggg tgtcttcaag caggtcttcg tcctcaaggt atttcttgat attgctggtt
    11581 gaactggtca atttcttaat cacgcgctca tttgttttga gggaggcctt gaaatagacg
    11641 atagtttttt ccaattccat gagctcaatc aattcttcat tacgagttga ttgatgcagt
    11701 tgactttcga tttgttcact cttgcggtcg attgaacgaa gggctgttag gtaaagctct
    11761 gcattgcgat aaagaatttg aaagataaaa cgtgaacgca tgaaggtata gaaattacgc
    11821 aatcgacggt tgataaagac atcaaggaca ggtagtggtt ccaaacacgt agtgataatg
    11881 gtttcctcag tgatgataat accaagcggg atggttacgt agtaggtgcg gttatttctt
    11941 tcctccgtga ccggcacgtc tacgataatc agggtatact cgtcttcaat ggtaatacga
    12001 gacatttctt ccgcatcgag cggtgctcga aggtcggcaa tatcaatatc gaaggtgttg
    12061 gcgatttcga gtgattcatt ttgagtcgga ttgacgagat tgatccaagt acccggttca
    12121 agcgtatcga tctctttaaa ttcagttgtt gtagagagaa aaacttgttt catatccctt
    12181 atcctttctc atttttcaga ttttttcaca ctgtactatt atactacaaa atcggccttt
    12241 tgggtaatag aatctcactt tttttggtat aatggtaagc aataatggac tagaaagaac
    12301 aaagatgcaa gataaaattg tcattcatgg ggcgcgtgcc cataatttaa aaaatattga
    12361 tgtggagatt ccgcgagaca agttggttgt cgtgactggc ttgtcaggtt cagggaagtc
    12421 cagtctggct tttgatactc tctatgcgga gggacaacgt cgctatgtag agagtttgtc
    12481 cgcctacgct cgtcagttct tgggaaatat ggaaaaacca gatgtagatg ccattgatgg
    12541 tctcagccca gctatttcca tcgaccagaa aacgactagt aaaaatcctc gctcgacggt
    12601 gggaacgacg actgaaatca atgactatct gcgtctcctc tacgcacgtg tggggacgcc
    12661 ttactgtatc aacggacatg gagctatcaa tgcttcttct gtggagcaaa tcgttgataa
    12721 ggttttggag ttacctgaac gccagcgctt gcagatcttg gctcctgtca tccgcaagaa
    12781 aaaaggccaa cataagagtg ttatcgagaa ggttcagaaa gacgggtatg ttcgtgtccg
    12841 tgtggatggg gaagtctatg atgtgaccga agtgccagag ttgtctaaga gcaagcaaca
    12901 caatatcgat gtcgtggttg accgtattgt tatcaaggag ggcattcgta gtcgtctctt
    12961 tgattccatt gaggctgccc ttcgtattgc agaaggttat gtcattatcg acaccatgga
    13021 cgactcggag ttgctcttct ctgagcatta tgcctgtcca gtttgtggat ttactgtccc
    13081 agagttagaa cctcgtctct tctctttcaa tgctcccttt ggctcttgta gtgagtgtga
    13141 cggcttgggg attaagctgg aggtggatac tgatttggta gtgccagatg ccagcaaaac
    13201 cttacatgag ggagcgctgg caccttggaa tcctatctca tccaactact atccaaacat
    13261 gttagagcag gccatgaaag tctttggagt ggctatggat aagccttttg aggacctgtc
    13321 agaagaagat aagaacttga ttctctacgg ctcagatggt aaggaattcc atttccatta
    13381 tgaaaatgaa tttggtggtg tgcgcgatat cgacattccg tttgagggag ttatcaataa
    13441 tatcaaacgt cgttaccatg aaaccaatag cgattacact cgcactcaga tgcgtctcta
    13501 catgaatgag ctgacctgcg gaacctgtca aggctatcgt ctcaatgacc aggccttgtc
    13561 tgtccgtgtg ggcggccagc aagggccaca tattggagaa atctcagacc tgtctatcgc
    13621 tgaccacttg gacttggtga gccagttaac tttgtctgaa aatgaagcca tcattgctcg
    13681 tcccattctc aaggaaatca aggatcgttt gaccttcctt aataatgtgg gtcttaacta
    13741 tctaaccctg tcacgttcag caggaaccct ttcaggtggg gaaagtcagc gcattcgttt
    13801 ggcaacccag attggttcca acctatcagg tgtcctctat atcctagacg agccgtcaat
    13861 cggtcttcac cagagggaca atgaccgcct gattgccagt ctgaaaaaga tgcgtgactt
    13921 gggcaatact cttatcgtgg tggaacacga cgaagatacc atgcgtgaag ctgattatct
    13981 gattgacgtt ggtcctggtg ccggtgtttt tggtggtgag attgttgcag caggtacacc
    14041 taagcaagtg gctcgcaaca gcaagtctat cacaggtcag tacttgtcag gcaaacgtgt
    14101 catcccagta ccagaagagc gccgtgtcgg aaatggtcgt tttattgaag tgacaggagc
    14161 gcgtgagaac aacttgcaaa atgtcacggc tcgctttcca ctaggaaaat ttatcgcagt
    14221 gacaggtgtg tcgggttcag ggaaatcgac tctaatcaac agcattctca aaaaagccat
    14281 tgcccagaag ctcaaccgta attcagacaa acctggtaag tttaagacta ttacagggat
    14341 tgagcatgtc gaccgtttga ttgatattaa ccagagccct atcggacgga cgccgaggtc
    14401 taacccagct acctatacag gagtttttga cgatatacgt gacctttttg ctcagacaaa
    14461 tgaagccaag attcgaggct acaagaaggg gcgcttcagt ttcaacgtca agggaggtcg
    14521 ctgtgaagct tgctcaggtg acgggattat caagattgag atgcacttct tgccagatgt
    14581 ttatgtggct tgtgaagttt gccacggaac ccgctataac agtgaaaccc tagaagttca
    14641 ctacaaggaa aagaatattt cgcaggtctt ggatatgacg gtcaacgatg cggtagaatt
    14701 tttccaacac attccgaaaa ttcaacgcaa actccagacc atcaaggatg taggtctagg
    14761 ctatgtgacc ttgggacagc cagctaccac cctttctggg ggagaagccc aacgtatgaa
    14821 gttagctagc gaactccaca aacgctcgac aggaaaatct ttctacattc tggatgagcc
    14881 gacgacaggg cttcatacag aggacattgc tcgcctgctc aaggttttag ctcgctttgt
    14941 agacgccggc aatacagtcc tcgtcatcga gcacaatctg gatgttatca agacggcaga
    15001 ccatatcatt gacttgggac ctgagggcgg tgtcggtggt ggaaccatca tcgtaacagg
    15061 aactccagaa gaagtagctg ccaacgaagc cagctataca ggacactatt tgaaaggaaa
    15121 gttacatcat gaataaacgc gtacaagcat ttctagctaa aatgcaagaa aaagaactag
    15181 atggtatcat catcaacaat cttaaaaacg tctattattt gactggtttt tggggctcaa
    15241 acggaacagt ctttatcagc cgtgaccgtc aggtcttagt gacagactct cgctatatca
    15301 tcgcagctaa gcaagaaacc agtggttttg agattgtggc tgatcgtgat gaattggctg
    15361 tcattgcagg aattgttaag gacatgaact tgactcgtat cggttttgaa gatgagattt
    15421 cagtgtctta ttaccaccgt atgcaggcag cttttgcagg tttgaacttg cttccacaaa
    15481 ctcagtttgt ggaaggtctt cgtatgatta aggatgaggc agagattgca gcgattcgca
    15541 aggcttgttc tatctcagac caagctttcc gcgatgcgct tgactttatc aaaccaggaa
    15601 aaactgaaat tgagattgcc aacttccttg atttccgcat gcgtgagttg ggagcatctg
    15661 gcttatcttt tgatacgatc ctagctagcg gtatcaattc ttctaaaccc catgcccatc
    15721 caatgcacaa accagtggag ttgggagaag ccatcaccat ggacttcggc tgtctctatg
    15781 accactatgt cagtgatatg acccggacta tctatctagg gcatgttagc gatgagcagg
    15841 cagagattta caatacggtt ctaaaagcta accaagcctt gattgaccaa gctaaggcag
    15901 gcttaggttt ccgtgacttt gacaaaatcc ctcgtgatat tatcattgag gcaggttatg
    15961 gtgactactt tactcacggc attggccacg gtattggtct ggatatccat gaggaaccct
    16021 actttagtca gacttctaca gaaactatta agacaggtat ggccttgacc gatgaaccag
    16081 gtatctatat cgaaggcaaa tatggcgttc gtatcgagga tgatatcctg attacagaga
    16141 caggttgtga attattgacc ctagctccaa aagagttgat agtcatttag ttgtttgtca
    16201 agaaaaaagt acgaaaatga cgaaaaaagt caaaaaaaat taaaaatagg tcgcaagtcg
    16261 gatgtttttt atggtataat agactaaact gatagtaaca tgtagcgaaa ggggtaggta
    16321 catgattaaa atttatacag tctcaagttg tactagctgt aaaaaagcaa aaacctggct
    16381 caatgcccac cagttaagtt ataaagaaca aaaccttggt aaagaaggaa ttacgagaga
    16441 agaattactg gatattctaa ccaaaacaga taacggaata gccagcatcg tttcgtctaa
    16501 aaatcgctat gccaaagccc ttggagtgga tattgaagat ttgagtgtca atgaagttct
    16561 caatctgatt atggaaacac cgagaatttt aaagagccca atccttgtag atgaaaaacg
    16621 cctgcaagtt ggctacaagg aagacgatat tcgtgccttc ctaccacgat ctgtccgtaa
    16681 tgtagaaaat gcagaagcac gtttgcgtgc agctctataa acatcaaggc tgggagcact
    16741 tcccagtctt attctatttt aatttcaaaa agaaagaaga aagaaatgaa aaaaatagtt
    16801 cttgttagtc tagctttcct ttttgtcctg gttggttgcg gacagaaaaa agaaactgga
    16861 ccagctacaa aaacagaaaa agatacgctt cagtcggcat tgccagttat tgaaaatgct
    16921 gagaagaata cagttgtaac taagactttg gtcttgccca agtcagatga tggtagccag
    16981 cagacacaaa caattactta caaagacaag acttttttga gtctagctat ccaacaaaaa
    17041 cgtccagtct ctgatgagtt gaagacttat attgaccaac atggagtgga ggaaactcaa
    17101 aaagctcttc ttgaagcgga ggagaaggat aagtctatca ttgaagctcg taaattggca
    17161 ggtttcaaac ttgaaacaaa actattgagc gcaacggaac ttcaaacaac gactagtttt
    17221 gattttcaag ttctggatgt caagaaggct tcccagttgg aacatctgaa gaatattggt
    17281 ttggaaaatc ttttgaaaaa tgaaccaagc aaatatattt cagatagatt ggcaaatggc
    17341 gcgacagaac aatagaaaat ccaaataaat agactgcctg aattgtagaa ggtaaggaat
    17401 tatgctataa tggtactatt ctaaggaaag agggtgttag aatgggattt actgaagaaa
    17461 cagtacgttt taaattggac gattccaata aaaaagaaat tagcgaaact ttgacagatg
    17521 tttatgcttc gttgaacgat aagggttaca acccaattaa ccaaatcgta ggttacgtat
    17581 tgagtggaga ccctgcctac gttcctcgtt ataataatgc acgaaatcaa atccgtaagt
    17641 atgagcgtga tgaaatcgtt gaggaattgg ttcgctacta cctcaaagga caaggagtcg
    17701 atctataacc tatgagaatt atgggattgg acgtcggttc aaaaacggta ggggtggcga
    17761 ttagcgatcc gcttggtttt acagctcaag ggcttgaaat catccagata aatgaagaac
    17821 aaggccaatt tggttttgac cgcgttaagg aattggttga tacttacaag gtggaacgat
    17881 ttgtagtggg cttgcctaaa aacatgaaca atacaagtgg accgcgcgta gaagctagtc
    17941 aagcctacgg agcaaagcta gaagagtttt ttggtttacc agtagactat caggatgaac
    18001 gcttgacaac agtggctgct gagcgcatgt tgattgaaca agcagatatc agtcgcaata
    18061 agcgcaagaa agtcattgat aagttagcag ctcagctgat tttacaaaat tatttagata
    18121 gaaaatttta atataaagga gaggctatgt cacacgatca taaccacgac cacgaagaac
    18181 gtgaactaat cacactagta gatgagcaag gaaatgaaac cttgtttgaa atccttttga
    18241 caattgatgg aaaagaagaa tttggtaaaa actatgttct tctagtacca gttaacgcag
    18301 aagaagacga agacggacaa gttgaaatcc aagcttactc attcattgaa aatgaagatg
    18361 gaacagaagg cgaattgcaa ccaatcccag aagactcaga agacgaatgg aacatgattg
    18421 aagaagtctt caacagcttt atggaggagt aaaaacgtcc gggggacgtt tttagccctg
    18481 cgctagaaat tagaaacgca ggtagtctgg gagactgtat cagcccaact ccagaaatgg
    18541 ggaagagttg gaacgtccag tgaacatttt taccccaact cttagaaatt gagaagagtt
    18601 ggaacatcta gtggatgttt ttagcccata ttcacattca tagtagctag ttattagcta
    18661 accaggtaag aggtcgggac gaaaatcctg gccttgtttt tattagtaac catactttaa
    18721 tgcgataatt gattggactt ttgtcaagga gatgtgtatg tttgaagtag aagaatggct
    18781 ccatagtcgg attggtttga attttcgatc aggtttgggc cgaatgcagc aagcggtgga
    18841 tttgttagga aatcctgagc agtcttaccc tattatccac gtaacaggga ctaatgggaa
    18901 aggatctacc attgctttta tgagggaatt atttatgggg catggcaaaa aagttgcgac
    18961 ctttacctcc cctcatatcg tatccatcaa tgaccgaatc tgcattaatg ggcaacctat
    19021 agcagacgca gactttatcc gtttggctga tcaggtaaag gagatggaga aaacgcttct
    19081 gcaaactcct gaccagttgt ccttttttga attgctgacc ttggttgctt ttctttattt
    19141 tagggagcag gaggtggatt tggttttatt agaagtggga attggtggct tacttgacac
    19201 gaccaatgtg gtaactggag agcttgctgt catcacctcc attgggcttg accatcaaga
    19261 aaccttgggt gatagtctag aagcaattgc agagcagaaa gctggtattt tcaaggctgg
    19321 taaaaaggca gtgattgcga aattgcctcc agaagctaga cttgtctgtc agaaaaaagc
    19381 cgaatcttta gctgttgacc tttatcaggc aggtcaagat ttttcagtgc tgaatggtga
    19441 tttttcaagc tctttactaa atctttcaca gctgaacata ggcttagaag gagcctatca
    19501 gcaggagaat gcggccttgg cgttgcaaac ttttcttctt tttatgggag aaagaaagga
    19561 agctattgat gaacaggctg taagaaaggc cttggaacag acccattggg ctggtcgctt
    19621 ggagcgtatt cgcccacaga tttacttgga tggtgctcat aacctccctg ccttgactcg
    19681 cttggttgag tttatcaaag aaaaagagca ggaaggctat cgacctcaaa tcctctttgg
    19741 atccttgaaa cgtaaggatt atcaagggat gttgggttat ctgactgaaa atttacctca
    19801 agtggaactc aaaatgaccg gctttgacta tcaagggtct ttggacgaga cagatgtaac
    19861 aggttaccat gtaattccct cttaccgaga atttatcagc agtttcgaag aaagggcaga
    19921 cgctcaagac ttgctgttcg ttacagggtc tctctatttt atctcagaag tacggggcta
    19981 cctgctggac cgtgagcaga taaattgacc cccttttttg aacttgttat actaggggaa
    20041 ttgctggtta gagaaaattt ctctaaattg gtagcagaaa ggaaattcat catgaaatta
    20101 aaaagattca cactttctct tgcttctcta gcaagtttta gtctcttagt agcttgttca
    20161 caaagagctc aacaggttca acagcctgtt gctcagcagg tccaacagcc tgctcaacag
    20221 aataccaata ctgcaaatgc aggaggtaac caaaatcaag cggctccagt acaaaaccaa
    20281 cctgttgctc aaccgaccga tattgatggg acttatactg gtcaggatga cggagaccgt
    20341 atcactttag tggtaactgg aacgactggt acatggactg agctcgaatc tgacggggat
    20401 cagaaagtca aacaggttac atttgattca gcaaatcaac gcatgattat tggcgatgat
    20461 gtcaaaattt acactgtaaa cggtaatcaa atcgtcgtag atgatatgga tagagaccca
    20521 tcggaccaaa tcgttttaac taaataagac tatgcaagta gaaagggctg gatttttcag
    20581 cctttttact tttacctaga aaataatcat aaatacttgc cttctaccga atacctgcgt
    20641 tatactagta tcaattactt gtttttagca ttcaaactat caaggagggg atatgaaata
    20701 taggaaattt caattattga tgtccaagta tggctttagt ctttcgatta tgctacttga
    20761 actttgtctt gtttttggtc tctttcttta tttaggacgc atggctccca ttttatggat
    20821 tactgtcctc attctactga gtatcatcac aatcatttcg atagtcaacc gtaatacgac
    20881 tcctgagaat aaggtaacct ggttgttagt agcctttgtg ccagtatttg gtcccttgct
    20941 ctatctgatg tttggtgaaa ggcgattgtc caaaaaagaa atcaaacaac tgaagaagct
    21001 aggctctatg catttccaag aagcaaatag ccagctacta aaagagaaat taaaagaaag
    21061 tgacaaggca gcttatggag tcatcaagtc cttattgagt atggatacca atgctgacat
    21121 ctatgatcaa actgcctcta cattttttcc taacggagaa gctatgtgga aaaagatggt
    21181 agaagatctt aaaaaggctg agaaatttat tttcttggaa tattacatta tagaagaagg
    21241 tttgatgtgg aatcgcatac tagatatact agagcaaaag gtagctcagg gtgtagaggt
    21301 taagatgctc tatgatgata tcggctgtat ggctacttta acaggagatt atgcacatcg
    21361 acttcgtcag ctgggcatcg aggcccataa attcaataaa gttattcctc gtttgacagt
    21421 ggcttataat aacagagatc atagaaaaat attgattgtt gatggtcaga tagcctatac
    21481 tggtggggtc aatctggcag atgagtacat taaccacgtc gagagatttg gttattggaa
    21541 ggatagtgga attcgcttag acggactagc agtaaaagcc ctgacacgct tatttttgac
    21601 cacttggtac attaatcgag gagaaattag tgattttgat caatatcatt tagaaaatca
    21661 ttctatcccg agtgacggtt taaccattcc atacggaagt ggacccaagc caatttttcg
    21721 agcgcaggta gggaaaaaag tttatcagag tttaatcaat caagcaacag aatcggtcta
    21781 tattacgaca ccttatttga ttatagatta tgatttaaca gagacaatca aaaatgcagc
    21841 tatgagaggg gtcgatgttc gaattatcac cccttacata ccagataaga agttcattca
    21901 gttagtcacg agaggagctt atcccgacct tctttctgct ggtgttcgga tttatgagta
    21961 tagtccaggt tttattcata gtaagcagat gttggtagac gaagattttg cggtggtggg
    22021 gacaatcaat ctcgactacc ggagcttggt acaccattat gaaaatgcag tcttactcta
    22081 taaaactcct tctataaggg aaatcgcccg agattttcga aatatatttg cagattctca
    22141 ggaagtctat cctcattcta tcaaaacgag ctggtatcaa aagcttgtaa aagaaatcgc
    22201 ccagctattc gcccctatct tataagaaat ctagaactta ggatacaaac cagccctatt
    22261 tttcttgtct tttactaata gaaagaaaga ggaggggaat tcatgctaac taaggaagaa
    22321 gtgaatgata tgattgagtt caaacagaca catttacacc gctttcggga aattgaaacc
    22381 tttgtgaaac tatgcaaaaa atcactcaaa cagccatcgc aagctgacaa tcctaggact
    22441 ttttgatata ctaagacaga taaattgaac aggagaaacg atatgagtgt gtatggtaga
    22501 gtagaagaag ttcataagga gaatcgtgaa cctctagaat accaaatcga acaagaatcg
    22561 catcatcgtg aatcaagtcg tcttcctttg gtgaaaattt tactatggag tacgcttgta
    22621 acggggataa ctctaggagt accgctatta ctcgacttaa tgagtgcaca agaagtgcag
    22681 gatttttatg caggttgggc gcttcatcag acagggaaga tttacagcga ctattatgga
    22741 agtcaaggtt tgctttatta tttgctgact tacgtgagtc agggcggatt tttctttgcc
    22801 atctttgagt ggttagcctt ggtagcagga ggatttttcc tttttagatc agcggacacc
    22861 ttgacagagc aaggagacca agctggacat ctggtgacta ttttttacat gctagttaca
    22921 ggtcttgctt ttggtggagg ctatgcgact cttttagcgc ttcctttctt attcgcagcc
    22981 tttagtttag ttgcggctta cctaagcaat ccaagccatg ataagggatt tgtacggatt
    23041 gggctagctt tggcaggcgg atttttcttt gctcccttat catcgctcct gtttattgct
    23101 gtagtgggtt taggcttgtt ggtctttaac cttgggcata gacgctttgc gcatgggttt
    23161 tatcagtttc ttgcagtggc tttaggtttt tcacttgtct tttatccaac tgcctactat
    23221 agtgctgcaa caggaagttt tggggatgcg attagtggta ttcgttatcc tattgacagt
    23281 attcgctttg attttacttc taaaatttta gagaatatgt ttttttatgg cttgttgtcc
    23341 cttggtttgg gatttgtggt ttgtatcttt ttaggtctct ttcaatccaa accctttaaa
    23401 ctatacgtca tttcggttcc tgcaagtctt gttgtaattt taggtttgat tttacttttc
    23461 ttttcacaag agcctctgca cgcttcttat ttgatggtcg tcttccctgt tttcctactt
    23521 ttattggtaa ccaatattaa gagtcaacag agggggcgta gtgctagaag aagccgaaga
    23581 gaaacgccag ttagcctatg gagtcgtttc ttcaaaggaa atctatatct gctagttttt
    23641 gggtttgtct atcttttgtc tgttcctttt ttgatgaagt ttgtccttta tccagtacct
    23701 tatcaagaac gtaatcgtct tgctgatttg gtaaaagagg agacaaatac ggaagatgct
    23761 atctatgcat gggatgatac tgcgactctt tatcgtaaga gtgagcgctt gtcgccatcg
    23821 gcgattttgt ccccgttgca ctatacagca actgaggaaa atcgtaataa gttacttaat
    23881 gacttgaaag aaaaacaacc taaggtgatt gtggtaaatg acaaggtggt agtctggtct
    23941 gaagtggaaa cacttttaaa agaaaattac caacaagtaa agactgatta ctcagagttt
    24001 aaagtctata aaattaaata accaaatcaa tatcttgtgt atttttagaa attttaggat
    24061 ttttaacaca agatattgat ttttcttttt agagtggtat aatacttttt agaaagaaca
    24121 ttttagaaaa gagcatgcgt atgattgcac tagaagaaaa aattacaatt ttgccaactc
    24181 tcttcgtcga gaaacgagat gggagacgtg ttgtatttga tgtggacaag attgacaagg
    24241 ctctccacaa ggcggctgac aaggttatgg atgtgacacc cctggttgaa aaacgcctca
    24301 atgatctgac tgagcgaatt attacagaaa ttcatagtcg ctttccacag ggaattaaga
    24361 tttacgaaat tcaaaatatc gtagaacatg aactccttga agccaaagaa tatgcgctgg
    24421 ctgaggagta tattacttat cggacacaga gggattttga gcgctcaaaa gcgacggata
    24481 tcaactttag tattcataaa cttctcaaca aagaccagac agttgtcaat gaaaatgcta
    24541 ataaagacag tgatgtcttt aacactcagc gtgatttgac agcagggatt gttgggaaat
    24601 caatcggact gcaaatgctt cctaagcacg tagccaatgc ccaccaaaag ggggatatcc
    24661 actatcacga tttggactac agtccctata cccctatgac caactgctgt ttgattgatt
    24721 ttaagggtat gttggaaaat ggttttaaga ttggaaatgc agaggtagag agtcccaagt
    24781 ctatccagac tgcgacagca cagatttctc aaatcattgc caacgttgct tctagccagt
    24841 acggtggctg ttcagctgac cgtatcgatg aaattttggc gccttatgca gagaagaact
    24901 atcaaaaaca tctcaaagat gcagaagagt gggtattgcc tgaaaaacgg gaagattacg
    24961 cttggaagaa aacgcaaaag gacatctacg atgccatgca atctcttgag tatgaaatca
    25021 atactctctt cacttcaaat ggacaaacac cttttacttc gttaggtttt ggtctgggaa
    25081 ccagtcgttt tgaacgagaa attcaaaaag ctattttaaa cattcgcatc aagggtcttg
    25141 gttcagaaca ccgtacggct atctttccta aacttatttt cactctgaaa agaggcctta
    25201 atttagagga aggaactccc aactacgaca tcaagcagtt ggctcttgag tgtgcaacca
    25261 aacggatgta tccagatgtt ttatcttacg ataagattgt tgacttgaca ggatccttca
    25321 aggtgcctat gggttgccgt tctttcctcc aaggatggaa ggatgaaaat ggtgtagaag
    25381 tcaattcagg tcgcatgaat ctgggtgttg tgacggttaa tctgcctcgt attgctcttg
    25441 agtctgaagg tgatatgaat aagttctggg aaatcttcaa cgagcgcatg aatatcgcag
    25501 aagatgctct tgtttaccgt gtcgaacgca ctaaagaggc gacaccagcg aatgctccta
    25561 tcctttatca gtacggtgct tttggccatc atctaggtaa agaagaaagt gttgaccagc
    25621 tctttaagaa tcgtcgtgcg accgtttcgc tgggctatat cggcttgtat gaagtagcga
    25681 cagttttctt tggtaacagc tgggaaagta atccagatgc taaggaattc acgctagaca
    25741 tcattcacga tatgaaacgc cgtgtagaag agtggtcaga ccaatatggc taccatttct
    25801 ctatctactc aacaccatcc gaaagtctga cagaccgttt ctgccgacta gatatagaca
    25861 agtttggctc tattcctgat atcacagaca aggaatacta caccaactct ttccactacg
    25921 atgttcgtaa aaatccaaca ccgtttgaaa aattggactt tgagaaagtc tatccagaag
    25981 caggtgcgtc aggtggtttc atccattatt gtgagtatcc agtccttcag caaaatccaa
    26041 aggccttgga agctgtctgg gattatgctt atgaccgtgt aggctatcta ggcaccaata
    26101 ctccgattga ccgttgctac aagtgtgact ttgaagggga ttttgaacca actgagagag
    26161 ggtttgcttg tccaaactgt ggcaatagcg accctaaaac agtagatgtg gtgaagcgaa
    26221 cttgtggcta cctaggtaat cctcaagcaa gaccgatggt caacgggcgt cacaaggaaa
    26281 tcgctgcgcg tgtcaaacat atgaatggtt caacgattaa aatagctggg catcaagtaa
    26341 caaattagaa agaaatgaaa tgggaaaata tcaactagac gataaggggc gcgcacaagt
    26401 gacccgttat cacgagaaac actctaaagg tggagctggt aagaaagaac gcttgcttag
    26461 cttcagagaa caatttttaa acaagaacaa gaaaaaataa aagtgagagc cagctctcgc
    26521 ttttctcata gtgggaggta aggatggaat tacgcagacc aagattagcg gataagaaag
    26581 ctgttttaga tatgatgaca gagtttgaaa aatttcagtc gcctcacgac ggcggtttct
    26641 gggatacaga gaactttgtg tatgaagact ggttagaaag caatcaggaa caggaaatgg
    26701 gaattaatct gcctgaagga tgggttcctg caattcagtt agtggctttt tctgagaaag
    26761 gtcaagcagt tggatttctt aatctccggt tgcgcctcag taactttcta ctagaagaag
    26821 gtgggcacat tggctactcc atccgtccat ctgaaagagg caagggttat gcaaaagaga
    26881 ctctccgtca gggcttgcaa gttgctaagg aaaagaacat caagaaagct ctggtgacct
    26941 gtagcgtgaa taatcctgct agcagagcag tcattctagc aaatggtgga atatttgagg
    27001 atgctcgcaa tggagtcgag cgttattgga tagaggtagc gaatgaataa tccaaaacca
    27061 caagaatgga aaagcgagga acttagtcaa ggtcgtatca ttgactacaa ggcctttaac
    27121 tttgttgatg gcgaaggcgt gcgtaactct ctctatgtag caggctgtat gtttcactgc
    27181 gagggatgtt ataatgttgc gacttggtct tttaatgctg gcattcccta tacagcagaa
    27241 ttagaagagc agatcatggc agatcttggt cagccctatg ttcaaggttt gactttgttg
    27301 ggaggggagc cttttctcaa tactggcatt ctcttgccac ttgttaagcg gattcggaaa
    27361 gaattgtcag acaaggacat ctggtcctgg accggctaca cttgggaaga aatgatgttg
    27421 gaaactccag ataaactgga actcttgtca ctgattgata ttcttgtcga tggaagatat
    27481 gatcgaacta agagaaatct tatgctccag tttcgaggtt cgtctaacca acgaattatc
    27541 gatgtgcaaa aatcgctcaa aagtgggcaa gtagtgattt gggacaagct caatgacgga
    27601 aaagaaagct atgaacaggt gaagagagaa tgaagaaaaa aggcttagta gaccaactag
    27661 tctcagagat cgagacgggg aaagtcagga cactgggaat atacggtcat ggagcttcag
    27721 gtaaatcaac ctttgcacag gaattgtccc aagctttaga ttctactaca gtaaatttgc
    27781 tagaaacaga tccctatatc acctccggac gctatttggt agtacccaag gacgcgccga
    27841 atcaaaaggt gacagccagt ctgccagtgg cgtatgaact ggagagtttg cagagagata
    27901 tctttgcctt gcaggcgggt atggatgtct tgacaattga agaaccttgg aaggctagtg
    27961 aagtcttgtc tggagccaaa ccaattttga ttgtcgaagg gatgtctgtt ggttttctac
    28021 ccaaggaact ctttgaaaaa accatctgtt tctacacgga tgaggagacc gaattaaagc
    28081 gacgccttgc tagagatacg actgtgagaa atcgcgatgc atcctttata ttggctagcc
    28141 atcagatgag acgggagcag tatctgcgat actataaaga aactgagtct aaggcggata
    28201 tcttagtgga ccaatcagaa gataaatttg atgtcaagag gacttaactt atgtatagaa
    28261 gaaaatccct aattttagaa agaaaaagta ggaaaacagt ttcatctcaa aaaaacgaaa
    28321 aaacctaaca aatcccttgc aatcgcaggg gatttgtgtt attctattat ggtgctgtaa
    28381 attacagcct tagttttgat gcaagaggtt gcgacacgct cggttgcatt gccacgcaac
    28441 gccgcgtcgg ttttcttgtg gagctagcct attatcttaa atagacgaaa aggagaaaaa
    28501 gatggcaaac aaaaaaatcc gtatccgttt gaaagcttac gaacaccgta cgcttgacac
    28561 agcggctgca aaaatcgtag aatcagctac tcgtacaggt gcacaagttg cgggtccaat
    28621 cccacttcca actgaacgta gcctctacac aatcattcgt gcgactcaca aatacaaaga
    28681 ctctcgcgaa caatttgaaa tgcgtacaca caaacgtttg atcgatatcg ttaacccaac
    28741 tcaaaaaaca gttgatgcct tgatgaaatt ggatcttcca agtggtgtaa acgtagaaat
    28801 caaactttaa tctaaaatat aaaagagcag aggctggtgt ttcaatctaa ttgaacacgg
    28861 gctaaactcg gtgtgaaaaa gataaacttc ctcgcgtctg ctagacactg cgttagtttc
    28921 ctattttcac tttgagtttg acgccctttg tatcttagac ttgagcataa aaaacgctcg
    28981 ttaaaaactt tttgaataaa aaatatagaa aaggaactat tttctcatga caaaaggaat
    29041 cttagggaaa aaagtgggaa tgactcaaat cttcactgaa gctggcgaat tgatccctgt
    29101 aacagttatt gaagcaactc caaacgttgt tcttcaagtt aaaactgttg aaacagacgg
    29161 atacaacgct atccaagttg gtttcgatga caaacgcgaa gtattgagca acaaacctgc
    29221 taaaggacat gtagcgaaag ctaacacggc tcctaagcgc ttcattcgtg aattcaaaaa
    29281 cgttgaaggc ttggaagttg gtgctgaaat tacagttgaa acattcgcag ctggagacgt
    29341 tgttgacgta actggtactt ctaaaggtaa aggtttccaa ggtgttatca aacgccacgg
    29401 acaatcacgt ggaccaatgg ctcacggttc tcgttaccac cgtcgtccag gttctatggg
    29461 acctgttgca cctaaccgcg tattcaaagg taaaaacctt gcagggcgta tgggtggcga
    29521 ccgcgtaaca attcaaaacc ttgaagttgt acaagttgtt ccagaaaaga acgttatcct
    29581 tatcaaaggt aacgtaccag gtgctaagaa atctcttatc actatcaaat cagcagttaa
    29641 agctggtaaa taataaagaa aggggaaatc agtcacaatg gcaaacgtaa cattatttga
    29701 ccaaactggt aaagaagctg gccaagttgt tcttagcgat gcagtatttg gtatcgaacc
    29761 aaatgaatca gttgtgtttg atgtaatcat cagccaacgc gcaagccttc gtcaaggaac
    29821 acacgctgtt aaaaaccgct ctgcagtatc aggtggtgga cgcaaaccat ggcgtcaaaa
    29881 aggaactgga cgtgctcgtc aaggttctat ccgctcacca caatggcgtg gtggtggtgt
    29941 tgtcttcgga ccaactccac gttcatacgg ctacaaactt ccacaaaaag ttcgtcgcct
    30001 agctcttaaa tcagtttact ctgaaaaagt tgctgaaaac aaattcgtag ctgtagacgc
    30061 tctttcattt acagctccaa aaactgctga atttgcaaaa gttcttgcag cattgagcat
    30121 cgattctaaa gttcttgtta tccttgaaga aggaaatgaa ttcgcagctc tttcagctcg
    30181 taaccttcca aacgtgaaag ttgcaactgc tacaactgca agtgttcttg acatcgcaaa
    30241 tagcgacaaa cttcttgtca cacaagcagc tatctctaaa atcgaggagg ttcttgcata
    30301 atgaatttgt atgatgttat caaaaaacct gtcatcactg aaagctcaat ggctcaactt
    30361 gaagcaggaa aatatgtatt tgaagttgac actcgtgcac acaaactttt gatcaagcaa
    30421 gctgttgaag ctgctttcga aggtgttaaa gttgccaatg ttaacacaat caacgtaaaa
    30481 ccaaaagcta aacgtgttgg acgttacact ggttttacta acaaaactaa aaaagctatc
    30541 atcacactta cagctgattc taaagcaatc gagttgtttg ctgctgaagc tgaataatct
    30601 aaggaggaaa tatcgtggga attcgtgttt ataaaccaac aacaaacggt cgccgtaata
    30661 tgacttcttt ggatttcgct gaaatcacaa caagcactcc tgaaaaatca ttgcttgttg
    30721 cattgaagag caaggctggt cgtaacaaca acggtcgtat cacagttcgt caccaaggtg
    30781 gtggacacaa acgtttctac cgtttggttg acttcaaacg taataaagac aacgttgaag
    30841 cagttgttaa aacaatcgag tacgatccaa accgttctgc aaacatcgct cttgtacact
    30901 acactgacgg tgtgaaagca tacatcatcg ctccaaaagg tcttgaagta ggtcaacgta
    30961 tcgtttcagg tccagaagca gatatcaaag tcggaaacgc tcttccactt gctaacatcc
    31021 cagttggtac tttgattcac aacatcgagt tgaaaccagg tcgtggtggt gaattggtac
    31081 gtgctgctgg tgcatctgct caagtattgg gttctgaagg taaatacgtt cttgttcgtc
    31141 ttcaatcagg tgaagttcgt atgattcttg gaacttgccg tgctacagtt ggtgttgtcg
    31201 gaaacgaaca acatggactt gtaaaccttg gtaaagcagg acgtagccgt tggaaaggta
    31261 tccgcccaac agttcgtggt tctgtaatga accctaacga tcacccacac ggtggtggtg
    31321 aaggtaaagc accagttggt cgtaaagcac catctactcc atggggcaaa cctgctcttg
    31381 gtcttaaaac tcgtaacaag aaagcgaaat ctgacaaact tatcgttcgt cgtcgcaacg
    31441 agaaataata ttaaactagt cgcttaagca actagtaaat ccgccagctc ggtagcgctc
    31501 cataggagtg caagccgctg tggtacaaca tttaaaggag aaaatataaa aatgggacgc
    31561 agtcttaaaa aaggaccttt cgtcgatgag catttgatga aaaaagttga agctcaagct
    31621 aacgacgaaa agaaaaaagt tattaaaact tggtcacgtc gttcaacgat cttcccaagt
    31681 ttcattggtt acactattgc agtttatgac ggacgtaaac acgtacctgt ttacatccaa
    31741 gaagacatgg taggccacaa acttggtgaa tttgcaccaa ctcgtactta caaaggtcac
    31801 gctgcagacg acaagaaaac acgtagaaaa taaggagaac ataaatggca gaaattactt
    31861 cagctaaagc aatggctcgt acagtacgtg tttcacctcg taaatcacgt cttgttcttg
    31921 ataacatccg tggtaaaagc gtagccgatg caatcgcaat cttgacattc actccaaaca
    31981 aagctgctga aatcatcttg aaagttttga actcagctgt agctaacgct gaaaacaact
    32041 ttggtttgga taaagctaac ttggtagtat ctgaagcatt cgcaaacgaa ggaccaacta
    32101 tgaaacgttt ccgtccacgt gcgaaaggtt cagcttcacc aatcaacaaa cgtacagctc
    32161 acatcactgt agctgttgca gaaaaataag gaggtaaaat cgtgggtcaa aaagtacatc
    32221 caattggtat gcgtgtcggc atcatccgtg attgggatgc caaatggtat gctgaaaaag
    32281 aatacgcgga ttaccttcat gaagatcttg caatccgtaa attcgttcaa aaagaacttg
    32341 ctgacgcagc agtttcaact attgaaatcg aacgcgcagt aaacaaagtt aacgtttcac
    32401 ttcacactgc taaaccaggt atggttatcg gtaaaggtgg tgctaacgtt gatgcactcc
    32461 gtgcaaaact taacaaattg actggaaaac aagtacacat caacatcatc gaaatcaaac
    32521 aacctgattt ggatgctcac cttgtaggtg aaggaattgc tcgtcaattg gagcaacgtg
    32581 ttgctttccg tcgtgcacaa aaacaagcaa tccaacgtgc aatgcgtgct ggagctaaag
    32641 gaatcaaaac tcaagtatca ggtcgtttga acggtgcaga tatcgcccgt gctgaaggat
    32701 actctgaagg aactgttccg cttcacacac ttcgtgcaga tatcgattac gcttgggaag
    32761 aagcagatac tacatacggt aaacttggtg ttaaagtatg gatctaccgt ggtgaagttc
    32821 ttccagctcg taaaaacact aaaggaggta aataaccaat gttagtacct aaacgtgtta
    32881 aacaccgtcg tgagttccgt ggaaaaatgc gcggtgaagc aaaaggtgga aaagaagtag
    32941 cattcggtga atacggtctt caagctacaa ctagccactg gatcactaac cgccaaatcg
    33001 aagctgctcg tatcgccatg actcgttaca tgaaacgtgg tggtaaagtt tggattaaaa
    33061 tcttcccaca caaatcatac actgctaaag ctatcggtgt gcgtatggga tctggtaaag
    33121 gggcacctga aggttgggta gcaccagtta aacgtggtaa agtgatgttc gaaatcgctg
    33181 gtgtatctga agagattgca cgtgaagcgc ttcgacttgc tagccacaaa ttgccagtta
    33241 aatgtaaatt cgtaaaacgt gaagcagaat aaggagaagg catgaaactt aatgaagtaa
    33301 aagaatttgt taaagaactt cgtggtcttt ctcaagaaga actcgcgaag cgcgaaaacg
    33361 aattgaaaaa agaattgttt gaacttcgtt tccaagctgc tactggtcaa ttggaacaaa
    33421 cagctcgctt gaaagaagtt aaaaaacaaa tcgctcgtat caaaacagtt caatctgaag
    33481 cgaaataata gactagggaa ggagaaattt caatggaacg caataatcgt aaagttcttg
    33541 ttggacgtgt tgtatctgac aaaatggaca agacaatcac agttgtagtt gaaacaaaac
    33601 gtaaccaccc agtctatggt aaacgtatta actactctaa aaaatacaaa gctcatgatg
    33661 aaaacaatgt tgccaaagaa ggcgatatcg tacgtatcat ggaaactcgc ccgctttcag
    33721 ctacaaaacg tttccgtctt gtagaagttg ttgaagaagc ggtcatcatc taatcaaacc
    33781 tgaaaggaga aaactgaaat gattcaaaca gaaactcgtt tgaaagtcgc agacaacagc
    33841 ggtgctcgcg aaatcttgac tatcaaagtt cttggtggtt caggacgtaa atttgcaaac
    33901 atcggtgatg ttatcgtggc atctgtaaaa caagctactc ctggtggtgc ggttaaaaaa
    33961 ggtgacgttg ttaaagcagt tatcgttcgt actaaatcag gtgctcgtcg tgctgatggt
    34021 tcatacatca aatttgacga aaacgcagca gttatcatcc gtgaagacaa aactcctcgc
    34081 ggaacacgta tctttggccc agttgcacgt gaattgcgtg aaggtggctt catgaagatc
    34141 gtgtcacttg ctccagaagt actttaattt ttaggaacaa actagtcccc tagcttcaag
    34201 ctagggtgcc cttatgggcg taagaaaaat caaggagaaa cctaatgttt gtaaaaaaag
    34261 gcgacaaagt tcgcgtaatc gctggtaaag acaagggaac agaagctgtt gtccttactg
    34321 cccttccaaa agtaaacaaa gttatcgttg aaggtgttaa cattgttaag aaacaccaac
    34381 gtccaactaa cgagcttcct caaggtggta tcatcgagaa agaagcagct atccacgtat
    34441 caaacgttca agttttggac aaaaatggtg tagctggtcg tgttggatac aaatttgtag
    34501 acggtaaaaa agttcgctac aacaaaaaat caggcgaagt gcttgattaa tcacgaagga
    34561 aaggagaagt ataatggcaa atcgtttaaa agaaaaatat cttaatgaag tagttcctgc
    34621 tttgacagaa caattcaact actcatcagt gatggctgtg cctaaagtag ataagattgt
    34681 tttgaacatg ggtgttggtg aagctgtatc aaacgctaaa agccttgaaa aagctgctga
    34741 agaattggca cttatctcag gtcaaaaacc acttatcact aaagctaaaa aatcaatcgc
    34801 cggcttccgt cttcgtgaag gtgttgcgat cggtgcaaaa gttacccttc gtggtgaacg
    34861 tatgtacgaa ttcttggata aattggtatc agtttcactt ccacgtgtac gtgacttcca
    34921 cggtgtccca acaaaatcat ttgatggacg cgggaactac acacttggtg tgaaagaaca
    34981 attaatcttc ccagaaatca acttcgatga cgttgacaaa actcgtggtc ttgacatcgt
    35041 tatcgtaaca actgctaaca ctgacgaaga gtcacgtgca ttgcttacag gccttggaat
    35101 gccttttgca aaataatata ggaggtaaat ctaatggcta aaaaatcaat ggtagctaga
    35161 gaggctaaac gccaaaaaat tgttgaccgt tatgctgaaa aacgtgctgc attaaaggcg
    35221 gcaggggact acgaaggttt atctaaatta cctcgcaacg cctcaccgac tcgtttacat
    35281 aatcgttgta gagttacggg gcgcccacat tcagtttacc gcaaatttgg tctgagtcgt
    35341 atcgcttttc gcgaacttgc gcataaaggt caaattcctg gtgtaacaaa agcatcttgg
    35401 taatttaaga tatcaagggt gtcaaaactc caagtaaaaa taggaaactt gacgaagaaa
    35461 ctaaagtttc taggaaagtt tatctttttc acacagagtt tagcccgggt tcaattgggc
    35521 ttgccaattt gaacccgagc tacagctttg gcaaaaaaga ccaatttgct ttggagcatt
    35581 gcttctgcat taaattgtct atttttgctc gtgctgttac gctctttgta tcatgtatta
    35641 actagcaagt gcaacttgca aactactagt aagaggagaa aaacaaaatg gttatgactg
    35701 acccaatcgc agacttccta actcgtattc gtaatgctaa ccaagctaaa cacgaagtac
    35761 ttgaagtacc tgcatcaaac atcaaaaaag ggattgctga aatccttaaa cgcgaaggtt
    35821 ttgtaaaaaa cgttgaaatc attgaagatg acaaacaagg cgtcatccgt gtatttctta
    35881 aatacggacc aaatggtgag aaagttatca ctaacttgaa acgtgtttct aaaccaggac
    35941 ttcgtgtcta caaaaaacgt gaagaccttc caaaagttct taacggactt ggaattgcca
    36001 tcctttcaac ttctgaaggt ttgcttactg ataaagaagc acgccaaaag aatgttggtg
    36061 gtgaggttat cgcttacgtt tggtaaaatc aagatacaaa gctcgtaaag aacaaagcaa
    36121 aattaggaag ttggagaagt ttgtttacaa acaagccaac ttatctattt tgcacagttc
    36181 ttagagcgtg ttcagttcag ctcttgaact aaataagtat ctgaaccccg tgaaaactgg
    36241 ccgttctggc ctgacaattt aacaggagaa aataaacatg tcacgtattg gtaataaagt
    36301 tatcgtgttg cctgctggtg ttgaactcgc taacaatgac aacgttgtaa ctgtaaaagg
    36361 acctaaagga gaacttactc gtgagttctc aaaagatatt gaaatccgtg tggaaggtac
    36421 tgaagtaact cttcaccgtc caaacgattc aaaagaaatg aaaactatcc acggaactac
    36481 tcgtgccctt ttgaacaaca tggttgttgg tgtatcagaa ggattcaaga aagaacttga
    36541 aatgcgtggg gttggttacc gtgcacagct tcaaggatct aaacttgttt tggctgttgg
    36601 taaatctcat ccagacgaag ttgaagctcc agaaggaatt acttttgaac ttccaaaccc
    36661 aacaacaatc gttgttagcg gaatttcaaa agaagtagtt ggtcaaacag ctgcttacgt
    36721 acgtagcctt cgttcaccag aaccatataa aggtaaaggt atccgttacg ttggtgaatt
    36781 cgttcgccgt aaagaaggta aaacaggtaa ataatgttga gtggttgatc atcaaccacc
    36841 aacctatttt ccaactttgt gcatagcaca cgatttaaaa ctaaagaggt gaaaactgtg
    36901 atttcaaaac cagataaaaa caaactccgc caaaaacgtc accgtcgcgt tcgcggaaaa
    36961 ctctctggaa ctgctgatcg cccacgtttg aacgtattcc gttctaatac aggcatctac
    37021 gctcaagtga ttgatgacgt agcgggtgta acgctcgcaa gtgcttcaac tcttgataaa
    37081 gaagtttcaa aaggaactaa aactgaacaa gccgttgctg tcggtaaact cgttgcagaa
    37141 cgtgcaaacg ctaaaggtat ttcagaagtg gtgttcgacc gcggtggata tctatatcac
    37201 ggacgtgtga aagctttggc tgatgcagct cgtgaaaacg gattgaaatt ctaataggag
    37261 gacactagaa aatggcattt aaagacaatg cagttgaatt agaagaacgc gtagttgctg
    37321 tcaaccgtgt tacaaaagtt gttaaaggtg gacgtcgtct tcgtttcgca gctcttgttg
    37381 ttgttggtga ccacaatggt cgcgtaggat ttggtactgg taaagctcaa gaagttccag
    37441 aagcaatccg taaagcagta gatgatgcta agaaaaactt gatcgaagtt cctatggttg
    37501 gaacaacaat cccacacgaa gttctttcag aattcggtgg agctaaagta ttgttgaaac
    37561 ctgctgtaga aggttctgga gttgccgctg gtggtgcagt tcgtgccgtt gtggaattgg
    37621 caggtgtggc agatattaca tctaaatcac ttggttctaa cactccaatc aacattgttc
    37681 gtgcaactgt tgaaggtttg aaacaattga aacgcgctga agaaattgct gcccttcgtg
    37741 gtatttcagt ttctgatttg gcataagaaa ggggataaaa tggctcaaat taaaattact
    37801 ttgactaagt ctccaatcgg acgcattcca tcacaacgta aaactgttgt agcacttgga
    37861 cttggcaaat tgaacagctc tgttattaaa gaagataacg ctgctatccg tggtatgatc
    37921 acagcagtat ctcacttagt aacagttgaa gaagtaaact aatgaagttt taggggatgt
    37981 gcactgtacc atcccctaaa actagatata gtcatctatg atgacatcgt ataggcgagt
    38041 tgatggggga gacaaccttt tctcccttat cggcgctagc attttacaaa agaggagaaa
    38101 ataaaaatga aacttcatga attgaaacct gcagaaggtt ctcgtaaagt acgtaaccgc
    38161 gttggtcgtg gtacttcatc aggtaacggt aaaacatctg gtcgtggtca aaaaggtcaa
    38221 aaagctcgta gcggtggcgg agttcgcctt ggttttgaag gtggacaaac tccattgttc
    38281 cgtcgtcttc caaaacgtgg attcactaac atcaacgcta aagaatacgc aattgtgaac
    38341 cttgaccaat tgaacgtctt tgaagatggt gctgaagtaa ctccagttgt tcttatcgaa
    38401 gcaggaattg ttaaagctga aaagtcaggt attaaaattc ttggtaacgg tgagttgact
    38461 aagaaattga ctgtgaaagc agctaaattc tctaaatcag ctgaagaagc tatcactgct
    38521 aaaggtggtt cagtagaagt catctaagag aggtgaccta tgttttttaa attattaaga
    38581 gaagctctta aagtcaagca ggttcgatca aaaattttat ttacaatttt tatcgttttg
    38641 gtctttcgta tcggaactag cattacagtt cctggtgtga atgccaatag cttgaatgct
    38701 ttaagtggat tatccttctt aaacatgttg agcttggtgt cggggaatgc cctaaaaaac
    38761 ttttcgattt ttgccctagg agttagtccc tatatcaccg cttctattgt tgtccaactc
    38821 ttgcaaatgg atattttacc caagtttgta gagtggggta aacaagggga agtaggtcga
    38881 agaaaattga atcaagctac tcgttatatt gctctagttc tcgcttttgt gcaatctatc
    38941 gggattacag ctggttttaa taccttggct ggagctcaat tgattaaaac tgctttaact
    39001 ccacaagttt ttctgacgat tggtatcatc ttaacagctg gtagtatgat tgtcacttgg
    39061 ttgggtgagc aaattacaga taagggatac ggaaacggtg tttccatgat tatctttgcc
    39121 gggattgttt cctcaattcc agagatgatt cagggcatct atgtggacta ctttgtgaac
    39181 gtcccaagta gccgtatcac ttcatctatc attttcgtaa tcattttgat tattactgta
    39241 ttgttgatta tttactttac aacttatgtt caacaagcag aatacaaaat tccaatccaa
    39301 tatactaagg ttgcacaagg tgctccatct agctcttacc ttccgttaaa ggtaaaccct
    39361 gctggagtta tccctgttat ctttgccagt tcgattactg cagcgcctgc ggctattctt
    39421 cagtttttga gtgccacagg tcatgattgg gcttgggtaa gggtagcaca agagatgttg
    39481 gcaactactt ctccaactgg tattgccatg tatgctttgt tgattattct ctttacattc
    39541 ttctatacgt ttgtacagat taatcctgaa aaagcagcag agagcctaca aaagagtggt
    39601 gcctatatcc atggagttcg tcctggtaaa ggtacagaag aatatatgtc taaacttctt
    39661 cgtcgtcttg caactgttgg ttccctcttc cttggtgtga tttccatttt accgattgca
    39721 gctaaagatg tatttggtct ttctgatgtt gttgcctttg gtggaacaag tctcttgatc
    39781 attatctcta caggtatcga aggaatcaag caattggaag gttacctatt gaaacgtaag
    39841 tatgttggtt tcatggacag aacagaataa aagtatttac tgaatcagta aatactgagg
    39901 gagtggaggt ttaaactctg acatttgtaa gagttggatc tcccctcttc tattttgttt
    39961 ttaaataggg gtgaaaagac tttttgcttc tatttaaaaa taaaataagg agatcaaatc
    40021 atgaatcttt tgattatggg cttacctggt gcaggtaagg gaactcaagc agcaaaaatc
    40081 gtagaacaat tccatgttgc acatatctca acaggtgata tgttccgcgc tgcaatggca
    40141 aatcaaactg aaatgggtgt tcttgctaag tcatatattg acaagggtga attggttcct
    40201 gacgaagtta caaatggaat cgtaaaagaa cgcctttcac aagatgatat taaagaaaca
    40261 ggattcttat tggatggtta cccacgtaca attgaacaag ctcatgcctt ggacaaaaca
    40321 ttggctgaac ttggcattga actagaaggt attatcaata ttgaagtgaa ccctgacagc
    40381 ctcttggaac gtttgagtgg ccgtatcatc caccgcgtaa ctggagaaac tttccacaag
    40441 gtctttaacc caccagttga ctataaagaa gaagattact accaacgtga agatgataag
    40501 cctgagacag taaaacgtcg tttggatgtt aatattgctc aaggagaacc aatcattgct
    40561 cactaccgtg ccaaaggttt ggttcatgac atcgaaggta atcaagatat caatgatgtc
    40621 ttctcagata ttgaaaaagt attgacaaat ttgaaataaa gcgtttttcg cacttgcaaa
    40681 aatccgctac aaatgttata ctgagatagt ctgacttata attgttgtct ctgtgtctag
    40741 aggcatcgaa tcgaaattta tggaggtgct tttgcgtggc aaaagacgat gtgattgaag
    40801 ttgaaggcaa agtagttgat acaatgccga atgcaatgtt tacggttgaa cttgaaaatg
    40861 gacatcagat tttagcaaca gtttctggta aaattcgtaa aaactatatt cgtattttag
    40921 cgggagatcg tgttactgtc gaaatgagtc catatgactt gacacgtgga cgtatcactt
    40981 accgctttaa ataatcgaaa aacttggagg gataagaaat gaaagtaaga ccatcggtca
    41041 aaccaatttg cgaatactgt aaagttattc gtcgtaatgg tcgtgttatg gtaatttgcc
    41101 cagcaaatcc aaaacacaaa caacgtcaag gataagatag aaaggagaaa acatggctcg
    41161 tattgctgga gttgatattc caaatgacaa acgcgtagta atctcattga cttatgttta
    41221 tggtatcgga cttgcaacat ctaagaaaat tttggctgct gctggaatct cagaagatgt
    41281 tcgtgtacgt gatcttacat cagatcaaga agatgctatc cgtcgtgaag tggatgcaat
    41341 caaagttgaa ggtgaccttc gtcgtgaagt aaacttgaac atcaaacgtt tgatggaaat
    41401 cggttcatac cgtggtatcc gtcaccgtcg tggacttcct gtccgtggac aaaacactaa
    41461 aaacaacgct cgcactcgta aaggtaaagc tgttgcgatt gctggtaaga aaaaataata
    41521 taggaggtaa aagtcttggc taaaccaaca cgtaaacgtc gtgtgaaaaa gaatatcgaa
    41581 tctggtattg ctcatattca cgctacattt aataacacta ttgttatgat tactgatgtg
    41641 catggtaatg caattgcttg gtcatcagct ggtgctcttg gtttcaaagg ttctcgtaaa
    41701 tctacaccat tcgctgctca aatggcttct gaagctgctg ctaaatctgc acaagaacac
    41761 ggtcttaaat cagttgaagt tactgtaaaa ggtccaggtt ctggtcgtga gtcagctatt
    41821 cgtgcgcttg ctgccgctgg tcttgaagta acagcaattc gtgatgtgac tccagtgcca
    41881 cacaatggtg ctcgtcctcc aaaacgtcgc cgtgtataat catcgcatta cactgctttt
    41941 cgtttaagag ggagtaacta aatgatcgag tttgaaaaac caaatataac aaaaattgat
    42001 gaaaataaag attatggcaa gtttgtaatc gaaccacttg aacgtggcta cggtacaact
    42061 cttggtaact ctcttcgtcg tgtacttcta gcttctctac caggagcagc tgtgacatct
    42121 atcaacattg atggtgtgtt acatgagttt gacacagttc caggtgttcg tgaagacgtg
    42181 atgcaaatca ttctgaacat taaaggaatt gcagtgaaat cgtacgttga agacgaaaaa
    42241 atcatcgaac tggatgttga aggtcctgct gaagtaacag ctggtgacat tttgacagat
    42301 agcgatattg aaattgtaaa tccagatcat tatctcttta caatcggtga aggttcttct
    42361 ctaaaagcga ctatgactgt taacagtggt cgtggatatg tacctgctga tgaaaataaa
    42421 aaggataatg caccagttgg aacacttgct gtagattcta tttatacacc agttacaaaa
    42481 gtcaactatc aagtggaacc tgctcgtgta ggtagcaatg atggtttcga caaattaacc
    42541 cttgaaatct tgacaaatgg aacaattatt ccagaagatg ctttagggct ttcagcacgt
    42601 attttgacag aacatcttga tttgtttaca aatcttactg agattgctaa gtcaactgaa
    42661 gtgatgaaag aagctgatac tgaatctgac gaccgtattt tagatcgtac gattgaggaa
    42721 ctggacttgt ctgtgcgttc atacaactgt ttaaaacgtg ccggtatcaa tactgtgcat
    42781 gatttgacag aaaaatctga agcagagatg atgaaagtac gaaatcttgg acgcaagagt
    42841 ttggaagaag tgaaactcaa actcattgat ttgggtcttg gattaaaaga taaataaagg
    42901 aggaatacat ggcttaccgt aaactaggac gcactagctc acaacgtaaa gcaatgcttc
    42961 gcgatttgac aactgacctt ttgatcaacg aatcaatcgt gacaactgaa gctcgtgcta
    43021 aagaaatccg taaaactgtt gaaaaaatga ttactctagg taaacgtggt gatttgcatg
    43081 cacgtcgtca agcagctgct ttcgtacgta atgaaatcgc atctgaaaac tatgatgaag
    43141 caactgataa gtacacttct actacagcac ttcaaaaatt gttctcagaa atcgcacctc
    43201 gttatgctga acgtaacggt ggatacactc gtatccttaa aactgaacca cgtcgtggtg
    43261 atgcagcgcc aatggcgatc atcgaattag tataaaatca tcaattttgt tgagtgttat
    43321 gatgatggag tcttgtgctc ttagtctagc tctggtctac cgctaggatt tcggtcctag
    43381 cgggaacact catcataagt tgggatagta gacgcttgtt tacgaaattg tttttttctt
    43441 aagaacaact tcgtaagcag gcgtttttga gtattttcgt tagaattatg ctatactatt
    43501 tgaaaagaat cctgtttaat gttaaggttt cttattttaa gaagaattgg agtttactta
    43561 tgaaagccat tataactgtt gttggtaaag ataaatctgg aattgttgca ggtgtttctg
    43621 gtaaaattgc agaattagga ttgaatattg acgatatctc tcaaactgtc ttggatgaat
    43681 attttacgat gatggctgtt gtatctagtg atgaaaagca agattttacc tatcttcgta
    43741 atgaatttga agcttttggg caaactttga atgtaaaaat caatattcag agtgcagcga
    43801 ttttcgaagc tatgtataat atctaggagg tcatcatgga tattagacaa gttactgaaa
    43861 ccatcgccat gattgaggag caaaacttcg atattagaac cattaccatg gggatttctc
    43921 ttttggactg tatcgatcca gatatcaatc gtgctgcgga gaaaatctat caaaaaatta
    43981 cgacaaaggc ggctaattta gtagctgttg gtgatgaaat tgcggctgag ttgggaattc
    44041 ctatcgttaa taagcgtgta tcggtgacac ctatttctct gattggggca gcgacagatg
    44101 cgacggacta cgtggttctg gcaaaagcgc ttgataaggt tgcgaaagag attggtgtgg
    44161 actttattgg tggtttttct gccttagtac aaaaaggtta tcaaaaggga gatgagattc
    44221 tcatcaattc cattcctcgc gctttggctg agacggataa ggtctgctcg tcagtcaata
    44281 tcggctcaac caagtctggt attaatatga cggctgtggc agatatggga cgaattatca
    44341 aggaaacagc aaatctttca gatatgggag tggccaagtt ggttgtattc gctaatgctg
    44401 ttgaggacaa tccatttatg gcgggtgcct ttcatggtgt tggggaagca gatgttatca
    44461 tcaatgtcgg agtttctggt cctggtgtgg tgaaacgtgc tttggaaaaa gttcgtggac
    44521 agagctttga tgtagtagcc gaaacagtta agaaaactgc ctttaaaatc actcgtatcg
    44581 gtcaattggt tggtcaaatg gccagtgaga gactgggtgt ggagtttggt attgtggact
    44641 tgagtttggc accaacccct gcggttggag actctgtggc acgtgtcctt gaggaaatgg
    44701 ggctagaaac agttggcacg catggaacga cagctgcctt ggccctcttg aacgaccaag
    44761 ttaaaaaggg tggagtgatg gcctgtaacc aggtcggtgg tctatctggt gcctttatcc
    44821 ctgtttctga ggatgaagga atgattgctg cagtgcaaaa tggctctctt aatttagaaa
    44881 aactagaagc tatgacggct atctgttctg ttggattgga tatgattgcc atcccagaag
    44941 atacgcctgc tgaaaccatt gcggctatga ttgcggatga agcagcaatc ggtgttatca
    45001 acatgaaaac aacagctgtt cgtatcattc ccaaaggaag agaaggcgat atgattgagt
    45061 ttggtggtct attaggaact gcacccgtta tgaaggttaa tggggcttcg tctgtcgact
    45121 tcatctctcg cggtggacaa atcccagcac caattcatag ttttaaaaat taagaaaata
    45181 ggagaaattt taagttctat ttaagattag atgtgtatac tataatcatt aaataaagac
    45241 ctcctaatat tatttgaaac agataacact gaattagttt gaatttgatt ttcatctaat
    45301 atctttattt aatgaactcc taaacttttt cataataatc tccttcaaaa gtcgcctgta
    45361 tgggtggctt ttattttatc attcatgata taatagaagc aaacggagga cggaaaatgg
    45421 taaaagtacg attgtatttg gtacgtcatg gcaagaccat gtttaacacg attggtcgcg
    45481 cgcaaggttg gagcgatact cccttaactg ctgaaggtga acgagggatt caagagttag
    45541 gaatcggttt gcgagaatct gatctacagt ttgagcgcgc ttattcgagt gattctggtc
    45601 gtaccattca gaccatggga attatacttg aagaacttgg cttgcagggg aaaatccctt
    45661 atcgcatgga caagcgtatc agagaatggt gtttcggtag ttttgatgga gcctatgatg
    45721 gcgatctttt catgggcatt attcctcgta tctttaatgt ggaccacgtt caccaattgt
    45781 cttatgctga actggctgag ggcttggtag aggtcgatac agctggttgg gctgaaggtt
    45841 gggaaaaact cagtggccga atcaaggaag gctttgaaat aattgcaaaa gaaatggaag
    45901 atcaaggtgg aggtaacgcc cttgttgtca gccatggaat gactattgga accattgttt
    45961 atctgattaa tggcatgcat ccgcatggtc tagataatgg tagcgtgacg attcttgaat
    46021 atgaggacgg tcagtttagg gttgaagttg tcggtgaccg tagttaccga gagctaggac
    46081 gtgagaagat ggaagaaggt tctatttaat cagtctagac ttgcttgcca tgagctaggg
    46141 atttgataag aatatcaaga taagaaaaaa cagccgaggg tactcctttc ggctgttttt
    46201 gatgtggaaa actaaagtgt aatgctattg cttttagaga ttttcataaa caagagcaag
    46261 gaacctactg ttagaacagt caggatagtt gacaaggctg cggctacacc gtaatttcct
    46321 ctgagaatct ctgtataaat agccacagtc attgttcttg ttttgacatt gtagaggagg
    46381 atagaagtag agagttttga aatcattgtg acccaagata agatggctcc agaaatgata
    46441 ccagatagca tcattggagt tgtaatctta gcaaagatat tgagacgact acttcctaag
    46501 ctttcagcag cttcttcaat acttggtgct atttgttgta agctagcaac agatgagcga
    46561 atagtataag gtaatcttct gacagataga gacataatca agatgaaagc agtccctgta
    46621 atcataagaa atccacttcc aaatagacca gtattgaagg aagaaatgaa ggcaatccct
    46681 agaacggttc ctggtacaat ataaggtacc atactgaggc tgtcaattaa gtttgtaaac
    46741 aaattccgtt ttctaacggc taggtaggag ataaatgtcg caaatagaac aactagaact
    46801 aaggcaatca aagggatacg aatggtattg aaaatagcag atcccatacg attgaaagct
    46861 accttgtaac tgtttggaga ataaccttta acaaatacca tacctgatgt ttttaggaaa
    46921 gaggtataaa ttaagtagat ttgaggtaaa acagagataa agataattcc gtagactgtt
    46981 gcataaatgg cagccatttt tccttttgta gtttttttag gctcaattgg atggagcaga
    47041 ttcatgctga aactgtagcg gtttgcaatg tgtttttgga taaggaaaat tgccaaggca
    47101 atgataatcg ccataattgc aaaagcagaa tttcctccaa cctcgctaat aaattgggta
    47161 taaatcagga cagggaaagt ccgatatcct tcgccaatca acataggcgt tccaaagtct
    47221 gagaatgctc tcataaatac aagcaaggag ctgctagtaa ggttgaaact aggagaggta
    47281 aaacaaccgt tacgataggt ttaaatccga aggaccccat gctttcagct gcttcaagta
    47341 gagaattgtc aatactgttc attgttccag caacatatag aaataccagt gggaatagtt
    47401 gcagtgtaaa gacaagtata cttcctttga atccataaat atcgatagct ggaagatgaa
    47461 gggcatttgt caaaaattta gtgatgacct catttcgtct cagcaagaga atccaggagt
    47521 aggctcctac gaaaggagct gacatggaag caatgataat caatatttgt agaaatttct
    47581 tccccttgaa gtcatacata gagaagagat aagctaatag ggttcctaca actaaggaag
    47641 tgacagtagc ggtaatggaa accctgaaac tgttgactag tgtctcagag tagtaggttt
    47701 tactaaagaa agtgacaaaa ttagctagtg agaattgtcc ttcatgtata agtgcttgct
    47761 tgagcacggt aacgatagga taaacgagaa agacaagata ggtaagaaag atgaagaaag
    47821 aggaagctgt ccaaatattt agttttttac attccatggt tgactccttt tatcaggttt
    47881 tgggaaccat ctgcagaaaa gatgtttaat ttttgcgtat tgattcgtag acgaatacga
    47941 ttgccttttt gtagttcttc ttcaaaagtt gattcttcac taacttgaat ttttgaggca
    48001 aaacctgtct caatgaaata ctccgtattt agtccaagat agacgctatc gctaatagtt
    48061 ccttcaatat ctccagattc atctttgata aactcttcgg gacgaatgct tacatgaata
    48121 gcttgctcct caacctgatc aagagctggc attcgaaggg catagccatc tgaaaagacg
    48181 atataagcgc cgtcgctccg tttttcaaga ttggcaggga taatatttgt gcgtccgata
    48241 aaggttgcca caaactcatt agctggttta tgatagagtt cttttggtcg gccgatttgt
    48301 tggatcaccc catctttcat aacagcaatt tggtctgaaa tagccatggc ttcttcttgg
    48361 tcgtgggtta cataaacagt tgtaattccc acttcgtgtt ggatttctcg gatggcttga
    48421 cgcatatcca agcgaagttt ggcctccaga ttactaagtg gctcgtccat gaggagaaca
    48481 cttggattaa ccgctaaggc gcatgccaag gtgacacgtt gttgttgtcc accactgagt
    48541 ttatcgggtt ttcgatccgc atattgagca atttgcatga gttcaagata cttgttggtc
    48601 tgttgaatca attcttcttt tgcataagac caaaagcaac gttgtctcgg acagtcaaat
    48661 gtgggaaaat agcgtagttt tggaaaacca tcccgatatt gcgtttgctg ggttccatat
    48721 tattgatttt tgtatcatcg aagtaaaatt ctcaatcttt gatactgttg aaacctgcaa
    48781 tcatacgaag aagggtcgtt ttcccacatc ctgaagctcc aagaagggta aagagacttc
    48841 cttttggaat tgtaatgttc aaattctcaa taacagggac atcgtggtag atttttttgg
    48901 cgttaataat tttgatctca ctcatagtga acctctttta ctgtttagat tggatatctg
    48961 taaagacttc gttgtatttc ttaacgatat ctgatttatt cttgatgaca taatcataat
    49021 cttcagtgag tgttttgatt ttgtcaattg gtttcatgtt ttcgcttgtt ttagcatttt
    49081 tacgaacagg acggttagta gtggttgtac caagtgtatc ttgtacttct tgagagataa
    49141 taaaatcgat aaatttcttg gcattttcca tatttttaga ttttttaacg atagcagcac
    49201 tagcaggtag gaagacggtt ccttcttttg gatagactac cttaatgtta gctccgtcat
    49261 ttaagagttt aactgctgga tcttcataag agagaccaac agtcatttct ccatcagcga
    49321 ctgctttata gacaccagat gaacttaaac cgattttata gtatattgaa actagaatag
    49381 tacacatcta cttctaaaac attgttagaa atcgatttga ctgtcctgat taatttgtcc
    49441 tgttcttatt tcattttact ataccatcaa taagtgtgaa aagatctttt acataagacc
    49501 aagccttatt atctttgtaa ccaccttgag cttgtagcat atttgttaat tgagcaaagg
    49561 cgctagaaga gtttgctggg tcagcagttg cgatttttcc ttttagttca ggtttgagaa
    49621 ggtcgctata tccttcgatg ttcatgcctt tagttaaatc agggtggacg attaaaacac
    49681 taccatctag tgtataagga gtagagaagc cagttgtgtt ttgatattct ttgataacat
    49741 tatcattttc ttttgaaata tagttttcaa agagttctcc gtgggtagca tattgtgtat
    49801 aagaaccacc aaagataaca tcagctacag gaacttcttt ttctgactct agttttttga
    49861 aaagttctcc agtaccagct tgaatcagtt ctattttgat accatatttt tcttcaaagg
    49921 caggaatagt tgctccaatt aagccttctg agtttggtga ataaacgact agcgaaccac
    49981 cgtctccttt atcagatgaa ctgtcatcgg cagattcatt agaagaacaa gcagcataat
    50041 acatccattt ctttttcatg atggatacct ccgttgtgtt atttaagttt attttaaaac
    50101 aatgtaagcg tttttaaaac ctacaattct attctatagt gtattgaatc tataacagta
    50161 caccttgact gctaaaatat ttctataaat taatttgact ttcctgatag agatgttcac
    50221 atcttatttc aattcactat attagagtaa aattctctac aaaaaaaaga atagcctatt
    50281 ttactatttt tccgagtgat ttcaattcct ttggggaaat atggagatac tttttaaatc
    50341 ctgacaaatg gttgtttctt tttctaaatc ggtgatactg tatcggagaa tgcgcgtgag
    50401 gtcacaaagg ctgcgataga gcttctatgg agaatttctt tttggagaga ttttttaaag
    50461 gaatgagaca tccgctacct ccttggaagg ttttttgtga taagtatagc agtttaaaaa
    50521 ttctagagca aggtaaaata gaaaaggttt ggctaaaatt ttttagctaa accttttgaa
    50581 aagttaagta tgtattatag atgcttgtta tctgcaaata tctagagcat ttcaaggaaa
    50641 taaactagaa ataacaatta atatggtggt tcagaaatac cttttgataa tcaataagat
    50701 cttcaggatg aagtgcgttg actccatcca tttcatattt ccgatttaat aaacgatatt
    50761 tgttttcacc aaattgatga aaagggagta gttgaacttg gtcgatattt aatgagttaa
    50821 atagagtagc gaatttttct gcatcctcta aactattgtt aaaattagga ataactggga
    50881 ttcttaaaac gatagtttta ttttgagaaa aagcataatg aatgttttta ataatcattt
    50941 gattaaaaac cccagtcact tttttatgtt ttatagaatt ataatgtttt aggtctgtgt
    51001 agataaaatc cacatattga attaaatcga taaatttttc atgatcaaca aaggcagtag
    51061 tttcaatggc agtgtgtatg tgatgttctt tagctgattt taagatggct ttagcaaatt
    51121 caaactgagc aaatatttca cctcctgata aagttaaacc tccaccggat tcttcgtaaa
    51181 attctttgtc ttttaatacc tctgtaataa tttcttctac agtcttttct tcaccgacta
    51241 aggtgaattt ctctcgttga gcatctttca ttttttcagg tttcattctt tgagattcag
    51301 gattagaaca ccatggacag cgcagaggac atccttttaa aaaaacagtt gtacgaatac
    51361 ccgggccgtc atgaattgaa aagtgttgaa tattaaaaat aattccttta gatatttcca
    51421 taagagttcc tcctcttcat aagtctatcc tatcacaaaa acgaaagaaa aacaattacg
    51481 aacgaaaggt taatttgttg ttttttgctt tttattttgg tagaataaaa cggaggtgta
    51541 aaatgaaaag attggaacaa attattaaat tagtatcaga atatgaaaag atcgacgtta
    51601 atacattatc ggaaaaatta aatgtatcga aagtaacgat tagaaaagat ttagataaat
    51661 tagagtcaaa aggtttatta cacagagagc atggatatgc tgtattaaat agtggagatg
    51721 acttaaatgt acgtttgtca attaattatg aaattaagag aaaaattgtt caggaagcag
    51781 taaaattggt gtcagataat gaaacaataa tgatagaatc tggatcgacc tgtgctttac
    51841 ttgctgagga aatttgcaag caaaaaagaa atgttacgat tgtaacaaat tcatttttta
    51901 tagcaaattt tgtgagagct tatgattcat gtcgtattat tgttcttggt ggagagtttc
    51961 agaaggattc acaggttact gtgggacctt tattaaaaga aatgatacag acttttcatg
    52021 tgcgtcaagc ttttgttggg acagatggct acgataaaga gatgggcttt acaggaaaag
    52081 atttaatgcg cagtgaggta gttcaatata tttcagcagc gtcggataaa gtcattgtac
    52141 taactgactc aagtaaattt gataaaaggg gtacagtaag aagatttgct ttaagtcaag
    52201 tctatgaagt aataacagac gaaaaacttt ctaaacaaaa tatagctaca ttagaaaatg
    52261 ctgggataat ggttaaggta gtttcgtaag aggttaagtg tatgaatcaa gataggaata
    52321 aactgctctc taaaattgct tatctgtatt atattgaaaa cttaaatcag tcacaaatag
    52381 cagcaaaatt aggaatttat agaacctcta ttagtagaat gttaacagaa gcaaggaatg
    52441 caggaattgt taaaattgaa atagagaatt ttgataccaa tatgtttaag ttggaaaatt
    52501 atgtaaaaga aaaatatggt ctggaaagtt tagaaattat tccaaatgaa tttgatgata
    52561 atccaacaat tttatctgaa agaatttctc aagttgcagc aggtgtcctt aggaatctaa
    52621 ttgatgataa tatgaaaatt ggcttttctt gggggaaaag tttaagtaat ttagtagatt
    52681 taattcacag taaaagtgtc cgaaatgttc acttctatcc tctagcaggt ggtcctagtc
    52741 acatacacgc taaataccat gtgaatacac tgatttatga aatgtctaga aaatttcatg
    52801 gagagtgtac atttatgaat gcaacgattg tgcaagaaaa taaattgtta gcagatggta
    52861 ttttgcaatc aagatatttt gaaaatttga aaaatagttg gaaagattta gatatagctg
    52921 tagtcggaat tggtgatttt agcaataaag gaaagcatca atggttagac atgcttacag
    52981 aggatgactt taaagaattg accaaagtta aaactgtagg agaaatttgt tgtcgatttt
    53041 ttgattcaaa aggtaaagaa gtctatgaaa acttacagga aagaacgata gcaatctctt
    53101 tggaagattt aaaaaatatt cctcaaagtt tagctgttgc ttacggtgat acgaaagtat
    53161 cttcgattct ttctgtcttg cgtgctaatt tagtaaatca tttgattaca gacaaaaata
    53221 caattttaaa agttttggaa gaagatgggg atttgacttt tagagagatt ctaggtgagt
    53281 gaaaatgata gactgattca gtttatcgtt tttcttttta gttgattgca catttgtgct
    53341 tatataaaca aaaatagttt atctgttgtt tttggattga caactttatt atgtagttgt
    53401 attctatagt tacaaaagaa aattttaaaa tttcaaatga aaaaagcttt ttacatagtg
    53461 aaatgaggag gaatttatgg aaattattgt tccagatcaa attatcatgg gtttaatttt
    53521 atatgctggc gatgcgaaac aacatattta taaagcatta gattacataa agaacggtac
    53581 atgtgaacga tgtgaagaag aaatccagtt agctgatgcc gccttattag aagctcataa
    53641 tctacaaaca aaattcttgg cacaggaagc gtctggtaca aagacagaaa ttacagctct
    53701 ctttgttcat tcacaagatc atctcatgac tagtatgacg gagattaatt taatcaaaga
    53761 aattattagt ttgagaaaag aacttcataa aaaataatac tagagtatta tcattgttat
    53821 taacatagag gaggaaaaca taatggtgaa gattggtttg ttttgtgcag caggtttttc
    53881 tactggtatg cttgtaaata atatgaaaat tgcagcgcaa gctagtggag ttgaggcaga
    53941 aatagaggcg ttttctcagt ctaaattagc ggattatgcg ccaaatatag atgttgcact
    54001 attgggtcca caagttgctt atacattaga taaatcaaaa gaaatttgtg ataagtgtga
    54061 tgttccgata gctgttattc cgatgatgga ctatggtatg ttagatggga aaaaagtatt
    54121 agatttggcc ctatctttga ttagtgggta agaaaaggag atttattatg tcaaagatgg
    54181 atgttcagaa aatcattgca ccgatgatga agtttgtgaa tatgcgtggc attatagctc
    54241 taaaagatgg gatgttagca attttgccat tgacagtagt tggtagtttg ttcttgatta
    54301 tgggacaatt gccgttcgaa ggattaaata agagcattgc tagtgttttt ggagctaatt
    54361 ggacagagcc gtttatgcaa gtatattcag gaacttttgc tattatgggt ctaatttctt
    54421 gtttttcaat tgcctattct tatgctaaga atagcggagt agaggcttta ccagctggag
    54481 ttctatctgt atctgcattc tttattttgc taagatcatc ttatatccct aaacaaggtg
    54541 aggcgattgg ggacgctatt agtaaagttt ggtttggagg ccaaggaatt atcggtgcta
    54601 tcattatagg tttggtagta ggaagtattt ataccttctt tataaagaga aaaattgtta
    54661 ttaagatgcc agaacaagtt ccacaagcta ttgccaaaca gtttgaagca atgattccag
    54721 catttgtaat tttcttatct tctatgattg tatatatttt agcgaagtca ttgactaatg
    54781 gcggaacatt catagaaatg atttattctg ctattcaagt tccgttgcaa ggtttaactg
    54841 gatctttgta tggtgctatt ggaattgcat tctttatatc atttttgtgg tggtttggtg
    54901 ttcatgggca atcggtagta aatggagtag tgacagctct gcttttatct aatcttgacg
    54961 ctaataaagc tatgttagcc tctgctaatc tatcattaga aaatggtgca catattgtta
    55021 ctcaacaatt tttagattca tttttaattc tatcaggttc agggattacg tttggtcttg
    55081 tagttgccat gctttttgca gcaaaatcaa aacaatacca agccttagga aaagttgcag
    55141 cttttccagc aatatttaac gtaaatgagc cagttgtatt tggatttccg attgtcatga
    55201 atccagttat gtttgtacct ttcattcttg ttcctgtact tgcagctgtg atagtatatg
    55261 gagctattgc aacaggtttc atgcagccat tctcaggggt aacattgcct tggagtacac
    55321 cagctattct atcaggattt ttggtgggtg gatggcaagg tgttgtgact cagttattag
    55381 tattggtgat atctacagtg gtttactttc cattctttaa gatacaagat cgtttagctt
    55441 accaaaatga aatcaaacaa tcttagaggt atttgtgtgt tactgttaaa ctcacacatt
    55501 tgtgctaaaa attagagagt taaaattttt ctagttaaaa gcttgaaaat ttctataaaa
    55561 atcggtatta tattttcgaa agaaataaaa atattttcga aagaaaggtg cttacgatgg
    55621 taaatacaga agtagcaaga acaacaatca agacagaata ttttggcagc cttactgaaa
    55681 ggatgaacaa atatcgagaa gatgttttaa ataaaaaacc ttatattgat gctgagagag
    55741 cagttctagc aacacgcgcc tatgaacgat acaaggaaca acctaatgtc ctaaaacgtg
    55801 catatatgct gaaagaaatt ttggaaaata tgtctatcta tattgaagaa gaatctatga
    55861 ttgcgggaaa tcaagcttct tccaataaag atgctcctat ttttccggaa tatacgctag
    55921 aatttgttct caatgagttg gatctttttg aaaagcgtga tggagatgtt ttctatatta
    55981 cagaagaaac aaaagaacaa cttagaagta ttgctccgtt ttgggaaaat aataatttac
    56041 gtgctagagc tggtgcctta ttacctgaag aagtgtcagt ttatatggaa acaggattct
    56101 tcggtatgga aggtaagatg aattctggag atgctcactt agcagttaac tatcagaaac
    56161 ttttgcaatt tggtttaaga ggttttgaag agcgggctcg taaagcaaaa gtagctctag
    56221 atttaacaga tccagcaagt attgataaat atcattttta cgactctata tttattgtaa
    56281 tcgatgctat taaagtatat gcaaagcgct ttgttgctct tgctaaaagt ttagccgaaa
    56341 atgcaaatcc taaacgtaag aaagaattac ttgagattgc agatatttgc tctagagtcc
    56401 catatgaacc ggcaactact tttgcagaag ctattcaatc agtttggttt attcaatgta
    56461 ttttacaaat tgaatctaat ggccactctc tttcatatgg ccgttttgat caatatatgt
    56521 atccatatat gaaggctgat ttagaaagtg gtaaagaaac agaagatagc attgttgaac
    56581 gtctgacaaa tctttggatt aagacaatta caattaataa ggttcgcagt caatcacata
    56641 cattttcttc agcaggaagt cctttatatc aaaatgttac aattggtgga cagactcgag
    56701 ataagaagga tgctgttaac ccattatctt atttggtatt aaaatcagtt gcacaaaccc
    56761 atctaccgca acctaatcta actgtacgtt accatgcagg tttagatgct cgtttcatga
    56821 atgagtgtat tgaagtgatg aaacttggtt ttggtatgcc tgcatttaat aatgatgaga
    56881 ttattattcc ttcttttatt gcaaaaggag tattggaaga tgatgcttat gattacagtg
    56941 ccattggatg tgttgaaacg gcagttccag ggaaatgggg ctatcgttgc acaggtatga
    57001 gttatatgaa cttccctaag gttctactta tcacgatgaa tgatggaatt gatccggctt
    57061 cgggtaaacg gtttgcacca agctttggtc attttaagga tatgaagaac ttttctgaat
    57121 tagaaaatgc ttgggataaa acactaagat atttgacacg aatgagtgtt attgttgaaa
    57181 attctattga tttatcattg gaacgagaag ttcctgatat tctatgttca gcattgactg
    57241 atgattgtat tggtcgtgga aaacacctta aagaaggtgg agcagtatat gattatatat
    57301 caggattgca agttggaatt gcaaatttgt cggattcatt agctgcaatt aaaaaattgg
    57361 tgtttgagga agaacgtata agcccaagtc agctttggca tgcactggaa acagattatg
    57421 ccggagaaga aggtaaggtc attcaagaaa tgttgattca tgatgcacct aagtatggta
    57481 atgatgatga ttatgctgac aaattggtta ctgctgctta tgacatttat gttgatgaaa
    57541 ttgctaaata tcctaataca cgttatggaa gagggcctat tggaggaatt cgttattcag
    57601 gaacatcttc tatatcagcc aacgtagggc agggacgtgg aacattagca actccagatg
    57661 gacgcaacgc gggtacaccg ttagcagagg gttgttcacc atcacataat atggatcaac
    57721 acggccctac atctgtttta aaatctgttt caaaattacc aacagatgaa atcgtaggtg
    57781 gggttctctt aaatcagaaa gtaaatcctc aaacgttagc caaagaagaa gataaattaa
    57841 aactaattgc tttgttacga acattcttta atcgtttaca tgggtaccat attcaataca
    57901 atgttgtttc cagagagacg ttgattgacg ctcagaaaca tcctgaaaaa cacagagact
    57961 taattgttcg tgttgcagga tactctgcat tcttcaatgt tctttctaag gcaacccaag
    58021 atgacattat aggacgtact gagcatactt tgtaaaataa agaggttctt tttatggaat
    58081 ttatgcttga cacattaaat ttagatgaga ttaaaaagtg gtctgaaatt ttgccgctag
    58141 ctggggtaac ttcaaatccc actattgcaa aaagagaggg ttctattaat ttttttgaac
    58201 gaatcaaaga tgtaagagaa ttgattggct ccacaccctc tattcatgtt caggtgattt
    58261 ctcaagattt tgaaggcatc ttaaaggatg ctcatgaaat tcgaagacaa gcaggagatg
    58321 atatatttat caaagtacct gttactccag ctggattacg tgcaataaag gtgctaaaaa
    58381 aagagggcta ccatatcact gcaacagcta tttatacagt tattcaggga ttattagcta
    58441 tcgaagtagg agcggattac ctagctccat attataatag aatggaaaat ctgaacattg
    58501 attcaaattc tgtcattcgt caattagctc ttgctattga tagacagaac tctcctagta
    58561 agattttagc tgcatccttt aaaaatgtag cacaagtaaa taatgcttta gctgcaggtg
    58621 cgcatgctgt tacagcagga gcagatgttt ttgaatcagc tttcgccatg ccatctatcc
    58681 aaaaggcggt tgatgatttt tctgacgatt ggtttgttac tcaaaatagt cgttccattt
    58741 agatagagag gaaatacata tgagaatttt tgctagtcct tctagatata ttcaggggga
    58801 aaatgccttg tttgaaaatg ccaaatcaat tttggatttg ggaaattacc cgattctatt
    58861 atgcgatcag ttggtttatg atattgttgg aaaacgattt gaagattatc tacataggta
    58921 tggtttccat attgttctgg cgctatttaa tggtgaagct tctgacaatg aaatcaatcg
    58981 agttgttgcc ttggctgaga aagaaaattg tgatagtatt atcggtcttg gtgggggaaa
    59041 gacgattgat agcgcaaaag ctattgcaga tttgattgaa aagcctgtta ttattgctcc
    59101 aacaattgca tcgaccgacg cacctgtatc tgctttatct gttatttata cagatgaagg
    59161 tgcatttgat cattatctat tttattctaa aaatccagat ttagttttgg ttgatacaaa
    59221 agttatttca caagccccta agcgtttatt agcgtctggt attgcagatg gtttagcaac
    59281 ttgggttgag gcgcgtgcgg ttatgcaggc aaatggaaaa actatgttgg gacaacagca
    59341 aacattggct ggagttgcaa ttgcgaagaa atgtgaagaa acgctgtttg cagatggttt
    59401 acaggctatg gcagcttgtg aagctaaagt ggtgacacca gcattagaaa atattgttga
    59461 agctaatact ttattgagtg gtctaggttt tgaaagtgga ggattagctg cggcgcatgc
    59521 aattcataat ggttttactg cattgacagg tgacattcat catttaacac atggtgaaaa
    59581 agtagcttat ggaactttag tacaactatt attggaaaat agacctaaag aagaacttga
    59641 taagtatatt gagttttaca aaaaaattgg tatgccaaca actctaaaag aaatgcattt
    59701 ggatcaagtt ggatatgatg atttaataaa agttggtaaa caagcaacta tggagggtga
    59761 gacaattcat cagatgccgt ttaagatttc gccctcagat gttgctcaag ctattatcgc
    59821 tgtagatgcc tatgtaaatt caaaataaac aataaggact actgttttcc aaatggtagt
    59881 cttttattga tccctgtatt gaattctata gcagattgaa ata
//
LOCUS       DAVBOD010000008        59123 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 640-05
            SAMEA1012484-rid20186543.denovo.008, whole genome shotgun sequence.
ACCESSION   DAVBOD010000008 DAVBOD010000000
VERSION     DAVBOD010000008.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012484
            Sequence Read Archive: ERR059358
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 59123)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 59123)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979948.1
            Genome Coverage       :: 595x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:03:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,266
            CDSs (total)                      :: 2,219
            Genes (coding)                    :: 2,091
            CDSs (with protein)               :: 2,091
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 71 of 128
            Pseudo Genes (incomplete)         :: 50 of 128
            Pseudo Genes (internal stop)      :: 33 of 128
            Pseudo Genes (multiple problems)  :: 22 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..59123
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012484-rid20186543.denovo.008"
                     /strain="NIG 640-05"
                     /db_xref="taxon:1313"
     gene            <1..170
                     /locus_tag="VQ862_000499"
     CDS             <1..170
                     /locus_tag="VQ862_000499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS630 family transposase"
                     /protein_id="HET3114896.1"
                     /translation="EQVLKEIRKRGFKNKAFRTLEDVMNQLQDVIQGLEKEVIKSIVN
                     RRWTRMLFESR"
     gene            complement(287..634)
                     /locus_tag="VQ862_000500"
     CDS             complement(287..634)
                     /locus_tag="VQ862_000500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003017645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HET3114897.1"
                     /translation="MNLNQLDIIVSNVPQVCADLEHILDKKADYADDGFAQFTIGSHC
                     LMLSQNHLVPLENFQSGIIIHIEVEDVDQNYKRLNELGIKVLHGPTVTDWGTESLLVQ
                     GPAGLVLDFYRMK"
     gene            complement(745..2520)
                     /gene="spxB"
                     /locus_tag="VQ862_000501"
     CDS             complement(745..2520)
                     /gene="spxB"
                     /locus_tag="VQ862_000501"
                     /EC_number="1.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000191798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate oxidase"
                     /protein_id="HET3114898.1"
                     /translation="MTQGKITASAAMLNVLKTWGVDTIYGIPSGTLSSLMDALAEDKD
                     IRFLQVRHEETGALAAVMQAKFGGSIGVAVGSGGPGATHLINGVYDAAMDNTPFLAIL
                     GSRPVNELNMDAFQELNQNPMYNGIAVYNKRVAYAEQLPKVIDEACRAAVSKKGPAVV
                     EIPVNFGFQEIDENSYYGSGSYERSFIAPALNEVEIDKAVEILNNAERPVIYAGFGGV
                     KAGEVITELSRKIKAPIITTGKNFEAFEWNYEGLTGSAYRVGWKPANEVVFEADTVLF
                     LGSNFPFAEVYEAFKNTEKFIQVDIDPYKLGKRHALDASILGDAGQAAKAILDKVNPV
                     ESTPWWRANVKNNQNWRDYMNKLEGKTEGELQLYQVYNAINKHADQDAIYSIDVGNTT
                     QTSTRHLHMTPKNMWRTSPLFATMGIALPGGIAAKKDNPDRQVWNIMGDGAFNMCYPD
                     VITNVQYDLPVINLVFSNAEYGFIKNKYEDTNKHLFGVDFTNADYAKIAEAQGAVGFT
                     VDRIEDIDAVVAEAVKLNKEGKTVVIDARITQHRPLPVEVLELDPKLHSEEAIKAFKE
                     KYEAEELVPFRLFLEEEGLQSRAIK"
     gene            complement(2727..4970)
                     /locus_tag="VQ862_000502"
     CDS             complement(2727..4970)
                     /locus_tag="VQ862_000502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HET3114899.1"
                     /translation="MTEIVKASLENGIQKIRIRAEKGYHPAHIQLQKGIPAEITFHRA
                     TPSNCYKEILFEEEGILEPIGVDEEKVIRFTPQELGRHEFSCGMKMQKGSYIVVEKTR
                     KSLSLLQRFWITSIFTVPLVILMIGMLTGSISHQVMHWGTFLATTPIMLVAGKPYIQS
                     AWASFKKHNANMDTLVALGTLVAYFYSLVALFAGLPVYFESAGFILFFVLLGAVFEEK
                     MRKNTSQAVEKLLDLQAKTAEVLSDDSYVQVPLEQVKVGDLIRVRPGEKIAVDGVVVE
                     GVSSIDESMVTGESLPVDKTVGDTVIGSTINHSGTLVFRAEKVGSETVLAQIVDFVKK
                     AQTSRAPIQDLTDKISGIFVPVVVILGIMTFWVWFVLLRDSVVVLGASFVSSLLYGVA
                     VLIIACPCALGLATPTALMVGTGRSAKMGVLLKNGTVLQEIQKVQTLVFDKTGTLTEG
                     KPVVTDIIGDEVEVFGLAASLEDASQHPLAEAIVKRASEAGLEFQTVENFQALHGKGV
                     SGRINGKQVLLGNAKMLDGMDISNTYQDKLEELEKEAKTVVFLAVDNEIKGLLALQDI
                     PKENAKLVISQLKKRGLRTVMLTGDNAGVARAIADQIGIEEVIAGVLPEEKAHEIHKL
                     QQSGKVAFVGDGINDAPALSVADVGIAMGAGTDIAIESADLVLTTNNLLGVVRAFDMS
                     KKTFHRILLNLFWAFIYNVVGIPIAAGVFSGVGLALNPELAGLAMAFSSVSVLTSSLL
                     LNFSKID"
     gene            complement(4980..5351)
                     /locus_tag="VQ862_000503"
     CDS             complement(4980..5351)
                     /locus_tag="VQ862_000503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000932058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupredoxin domain-containing protein"
                     /protein_id="HET3114900.1"
                     /translation="MLNSIVTIICIALIAFILFWFFKKPEKSGQKAQQKNGYQEIRVE
                     VMGGYTPELIVLKKSVPARIVFDRKDPSPCLDQIVFPDFGVHANLPMGEEYVVEITPE
                     QVGEFGFACGMNMMHGKMIVE"
     gene            complement(5362..5757)
                     /locus_tag="VQ862_000504"
     CDS             complement(5362..5757)
                     /locus_tag="VQ862_000504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopY/TcrY family copper transport repressor"
                     /protein_id="HET3114901.1"
                     /translation="MQISDAEWQVMKIIWMQGEQTSTDLIRVLAERFDWSKSTIQTLL
                     ARLVEKECLTRKKEGKSFVYSALLTLDQSRDLLVQDIKDKVCSRRIRNLLADLIVECE
                     FTQTDLEDLEAVISEKKSSAVTEVRCNCM"
     regulatory      5941..6039
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            6123..6914
                     /gene="thiD"
                     /locus_tag="VQ862_000505"
     CDS             6123..6914
                     /gene="thiD"
                     /locus_tag="VQ862_000505"
                     /EC_number="2.7.1.49"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HET3114902.1"
                     /translation="MTYLPVALTIAGTDPSGGAGIMADLKSFQARDVYGMAVVTSLVA
                     QNTRGVQLIEHVSPQMLKAQLESVFSDIPPQAVKTGMLATTEIMEIIQPYLKKLDCPY
                     VLDPVMVATSGDALIDSSARDYLKTNLLPLATIITPNLPEAEEIVGFSIHDPEGMQRA
                     GRLILKEFGPQSVVIKGGHLKGGAKDFLFTKNEQFVWESPRIQTCHTHGTGCTFAAVI
                     TAELAKGKSLYQAVDKAKAFITKAIQDAPQLGHGSGPVNHTTFKD"
     gene            complement(7123..7755)
                     /locus_tag="VQ862_000506"
     CDS             complement(7123..7755)
                     /locus_tag="VQ862_000506"
                     /EC_number="2.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001078228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine phosphate synthase"
                     /protein_id="HET3114903.1"
                     /translation="MNREALRLYLVTNRYQDSVESFLAKVETACRSGVTIVQLREKNL
                     TTNQYYQLAKQVKEITDAYQVPLIIDDRLDVCLAVDAAGLHIGDDELPVSVARKVLGP
                     EKILGVTAKTVKRALEAEKSGADYLGTGAIFPTTTKENAPITLISTLKTICQTVAIPV
                     VAIGGLTSENIDQLMGTGIAGVAVVRDLMQAEDIEAKTQAFLTKLHDILS"
     gene            complement(7748..8551)
                     /locus_tag="VQ862_000507"
     CDS             complement(7748..8551)
                     /locus_tag="VQ862_000507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyethylthiazole kinase"
                     /protein_id="HET3114904.1"
                     /translation="MQALTNPFPIGSSSLIHCMTNEISCEMLANGILALGCKPVMADD
                     PREVLDFTKQSQALFINLGHLSAEKEKAIRMAASYANQSSLPMVVDAVGVTTSSIRKS
                     LVKDLLDYRPTVLKGNMSEIRSLVGLKHHGVGVDASAKDQETEDLLQVLKDWCQTYPG
                     MSFLVTGPKDLIVSENQVAVLENGCTELDWITGTGDLVGALTAVFLSQGKTGFEASCL
                     AVSYLNIAAEKIVVQGMGLEEFRYQVLNQLSLLRRDENWLDTIKGEVYE"
     gene            complement(8551..9075)
                     /gene="thiW"
                     /locus_tag="VQ862_000508"
     CDS             complement(8551..9075)
                     /gene="thiW"
                     /locus_tag="VQ862_000508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001225563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy coupling factor transporter S component
                     ThiW"
                     /protein_id="HET3114905.1"
                     /translation="MRKHQLQVHKLTILSMMIALDVVLTPIFRIEGMAPMSSVVNILA
                     GIMMGPVYALAMATVTAFIRMTTQGIPPLALTGATFGALLAGLFYKYGRKFYFSALGE
                     IVGTGIIGSIVSYPVMVLFTGSAAKLSWFIYTPRFFGATLIGTAISFIAFRFLIKQEF
                     FKKVQGYFFAERIE"
     gene            complement(9080..9772)
                     /gene="tenA"
                     /locus_tag="VQ862_000509"
     CDS             complement(9080..9772)
                     /gene="tenA"
                     /locus_tag="VQ862_000509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiaminase II"
                     /protein_id="HET3114906.1"
                     /translation="MEFTDIAMELSKKAWQASFHHPFILQLQEGNLEPAIFRYYLIQD
                     AYYLKAFSEIYHLLADKTSNQEMKRLLKQNAQGLVEGELFIRQQFFKELEINDQEMEQ
                     HPIAPTCYHYISHIYRQFAEPNLAIAFASLLPCPWLYHDIGKSLNLKPSPNPLYQQWI
                     ETYITDELEQQIREEGALVNQLYRESDETDKQKMLDAFHISVHMEAKFWEMAYQHQTW
                     KSDLQSLEKGEE"
     gene            complement(9783..10433)
                     /locus_tag="VQ862_000510"
     CDS             complement(9783..10433)
                     /locus_tag="VQ862_000510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt ABC transporter permease"
                     /protein_id="HET3114907.1"
                     /translation="MVKVATQTPIISLFLLILSLETSFIPSIALNLSVVAFCILFMLY
                     YRRFKMLAWMIILAILPSFANYWAVQLHGDASQAVMLGTRAFVTVCIGLVFVSSISLK
                     ELLLYLAQKGLSRSWSYALIVVFNSFPLIQQEIKSLKEACLLRGQKLHFWSPLIYSKV
                     LMTVFRWRHLYLRALSAHGYDEHAQLKNSYRTFYIPKKTKLIYLLFFLLLQTSLFL"
     gene            complement(10435..11820)
                     /locus_tag="VQ862_000511"
     CDS             complement(10435..11820)
                     /locus_tag="VQ862_000511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000522086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3114908.1"
                     /translation="MGLELRAIQSPIFSEPFDFTFHAQAFTLLVGSSGSGKSSLFQMI
                     AQVSSLPYSGQVLIDGSEVSQLSIIARVQKVGILLQNPNHQFTMENLFEELIFTLENI
                     GYHLQEIDSKIAEVVQQCRCEAILHRPIHHLSGGEKQKAALAVLFAMNPRVYLLDEPF
                     ASIDRKSRIEILEILKELALDGKTVILCDHDLSDYKAYIDHMVELRDGKLREINQIPS
                     YEMTQVASKEVASSPELFHMNRVTGELGNRPLFSIADFTFYQGISCILGDNGVGKSTL
                     FRSILQFQKYKGRIAWKGTVLKKKKSLYRDLTGVVQEAEKQFIRVSLREELQLDGPDS
                     ERNQRIFQALRYFDLEQAVDKSPYQLSGGQQKILQLLTILTSKASVILLDEPFAGLDD
                     RACHYFCKWIVEERNQGRSFLLISHRLDPLISVVDYWIEMTSQGLRHVKEVTITKPLT
                     SQSSNTQGEVR"
     gene            complement(11821..12381)
                     /locus_tag="VQ862_000512"
     CDS             complement(11821..12381)
                     /locus_tag="VQ862_000512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000915269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HET3114909.1"
                     /translation="MLKKWQLKDVILLAFLSIFFGGVFVGSGYVYNILSLLLTPLGLQ
                     AFANEILFGLWCMAAPIAAIFVPRVGSATIGEVLAALAEVLYGSQFGLGALLSGLVQG
                     LGSEFGFIVTKNRYESWLSLTANSIGITLVSFVYEYIKLGYYAFSLPFVLSLLVVRFI
                     SVYFFCTILVRAIVKLYHQFATGGKA"
     regulatory      complement(12643..12731)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            complement(12940..13569)
                     /locus_tag="VQ862_000513"
     CDS             complement(12940..13569)
                     /locus_tag="VQ862_000513"
                     /EC_number="2.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000468574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine phosphate synthase"
                     /protein_id="HET3114910.1"
                     /translation="MFHKELLKLYFICGTTTCQGKNLYTVVEEALKGGITLFQFREKG
                     EGALEGLEKLELAIQIKELCKKYNVPFIVNDDIDLAMEIDADGVHVGQDDIGVDEIRK
                     LMPDKIIGLSIKNEEEFQQSKVEYVDYVGVGPVFDTQSKDDAGGAIGYEGLELMRKLL
                     PQMPLVAIGGIQTKHIKDIIKTNVDGVSIISAISYAKNIEKTVREMSEQ"
     gene            complement(13571..14353)
                     /gene="thiM"
                     /locus_tag="VQ862_000514"
     CDS             complement(13571..14353)
                     /gene="thiM"
                     /locus_tag="VQ862_000514"
                     /EC_number="2.7.1.50"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000202454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyethylthiazole kinase"
                     /protein_id="HET3114911.1"
                     /translation="MTSLKLLKEKAPLVICITNDVVKNFTANGLVALGASPAMSEFPA
                     DLEDLLKYAGGLLINIGTLTDENWKLYQAALKIAEKYNVPAVLDPVACGAGEYRKKVA
                     DDLINNYKLAAIRGNAGEIASLVGIDVASKGVDSAGVDNIDEIALAANEKFNIPIVVT
                     GEVDAIAVNGEVVTIHNGSAMMPKVIGTGCLLGAVVASFIGLEKGQELKSLETAMLVY
                     NIAGEMAEKRPNGHLPGTFKVEFINALYEITDEDVKKFKRVK"
     gene            complement(14764..15303)
                     /locus_tag="VQ862_000515"
     CDS             complement(14764..15303)
                     /locus_tag="VQ862_000515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000449826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TenA family protein"
                     /protein_id="HET3114912.1"
                     /translation="METQDYAFQPGLTVGELLKSSQKDWQAAINHRFVKELFAGTIEN
                     KVLKDYLIQDYHFFDAFLSMLGACVAHADKLESKLRFAKQLGFLEADEDGYFQKAFKE
                     LKVAENNYLEVTLHPVTKAFQDLMYWAVASSDYAHLLVMLVIAEGLYLDWGSKDLALP
                     EVYIHSEWINLHRGPFFAE"
     regulatory      complement(15518..15606)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            complement(15860..16996)
                     /gene="lctO"
                     /locus_tag="VQ862_000516"
     CDS             complement(15860..16996)
                     /gene="lctO"
                     /locus_tag="VQ862_000516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate oxidase"
                     /protein_id="HET3114913.1"
                     /translation="MSYKTSNAEGHVDFINTYDLEPMAQQVIPKAAFGYIASGAEDTF
                     TLRENIRAFNHKLIVPHTLCDVENPSTEIEFAGEKLSSPIIMAPVAAHKLANEQGEVA
                     TARGVHEFGSLYTTSSYSTVDLPEISEALQGTPHWFQFYFSKDDGINRHIMDRVKAEG
                     YKAIVLTADATVGGNREVDKRNGFVFPVGMPIVEEYLPEGAGKSMDFVYKSAKQRLSP
                     RDVEFIAEYSGLPVYVKGPQCREDVERSLAAGASGIWVTNHGGRQIDGGPAAFDSLQE
                     VAEAVDRRVPIVFDSGVRRGQHVFKALASGADLVAIGRPVIYGLALGGSVGVRQVFEH
                     LNAELKTVMQLSGAQTIEDVKHFKLRHNPYNPTFPVDPRDLKLY"
     gene            complement(17622..19112)
                     /gene="lysS"
                     /locus_tag="VQ862_000517"
     CDS             complement(17622..19112)
                     /gene="lysS"
                     /locus_tag="VQ862_000517"
                     /EC_number="6.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003055423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysine--tRNA ligase"
                     /protein_id="HET3114914.1"
                     /translation="MSTEHMEELNDQQIVRREKMAALREQGIDPFGKRFERTANSQEL
                     KDKYANLDKEQLHDKNETATIAGRLVTKRGKGKVGFAHLQDREGQIQIYVRKDAVGEE
                     NYEIFKKADLGDFLGVEGEVMRTDMGELSIKATHITHLSKALRPLPEKFHGLTDVETI
                     YRKRYLDLISNRESFERFVTRSKIISEIRRYLDQKGFLEVETPVLHNEAGGAAARPFI
                     THHNAQNIDMVLRIATELHLKRLIVGGMERVYEIGRIFRNEGMDATHNPEFTSIEVYQ
                     AYADFQDIMDLTEGIIQHAAKSVKGDGPVNYQGTEIKINEPFKRVHMVDAIREITGVD
                     FWQDMTLKEAKAIAAEKKVPVEKHYTEVGHIINAFFEEFVEETLIQPTFVYGHPVAVS
                     PLAKKNPEDQRFTDRFELFIMTKEYGNAFTELNDPIDQLSRFEAQAKAKELGDDEATG
                     IDYDYIEALEYGMPPTGGLGIGIDRLCMLLTDTTTIRDVLLFPTMK"
     gene            complement(19240..19386)
                     /locus_tag="VQ862_000518"
     CDS             complement(19240..19386)
                     /locus_tag="VQ862_000518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactate oxidase"
                     /protein_id="HET3114915.1"
                     /translation="MSYKTSNAEGHVDFINTYDLEPMAQQVIPKAAFGYIASGAEDTF
                     TSFQ"
     gene            19613..20281
                     /locus_tag="VQ862_000519"
     CDS             19613..20281
                     /locus_tag="VQ862_000519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006531263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HET3114916.1"
                     /translation="MVEQYLPLYQKAFFLTLHIAVWGILGSFLLGLIVSIIRHYRIPV
                     LAQVATAYIELSRNTPLLIQLFFLYFGLPLIGIVLSSEVCATLGLVFLGGSYMAESFR
                     SGLEAISQTQQEIGLAIGLTPLQVFRYVVLPQATAVVLPSFSANVIFLIKKTSVFSAV
                     ALADLMYVAKDLIGLYYETDIALAMLVVAYLIMLLPISLVFSWIERRTCHAGFGNPST
                     LSRK"
     gene            20241..20621
                     /locus_tag="VQ862_000520"
     CDS             20241..20621
                     /locus_tag="VQ862_000520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001154138.1"
                     /note="The N-terminal region of this protein, as described
                     by TIGR01726, is a three transmembrane segment that
                     identifies a subfamily of ABC transporter permease
                     subunits, which specificities that include histidine,
                     arginine, glutamine, glutamate, L-cystine (sic), the
                     opines (in Agrobacterium) octopine and nopaline, etc;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HET3114917.1"
                     /translation="MQDSGIQVLFQGNNLLRILQGLGVTIGISILSVLLSMMFGTVMG
                     IIMTSHSRIIRFLTRLYLEFIRIMPQLVLLFIVYFGLARNFNINISGETSAIIIFTLW
                     GTAEMGDLVRGAITSLPKHQFESG"
     gene            20631..20918
                     /locus_tag="VQ862_000521"
     CDS             20631..20918
                     /locus_tag="VQ862_000521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HET3114918.1"
                     /translation="MTNVQLYYHIIIPQVLRRLLPQAINLVTRMIKTTSLVVLIGVVE
                     VTKVGQQIIDSNRLTIPTASFWIYGTILVLYFAVCYPISKLSTHLEKHWRN"
     gene            20919..21682
                     /locus_tag="VQ862_000522"
                     /pseudo
     CDS             20919..21682
                     /locus_tag="VQ862_000522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000401.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
     gene            21694..22560
                     /locus_tag="VQ862_000523"
     CDS             21694..22560
                     /locus_tag="VQ862_000523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000765259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine ABC transporter substrate-binding
                     protein"
                     /protein_id="HET3114919.1"
                     /translation="MKLFKPLLTVLALAFALIFITACSSGGNAGSSSGKTTAKARTID
                     EIKKSGELRIAVFGDKKPFGYVDNDGSYQGYDIELGNQLAQDLGVKVKYISVDAANRA
                     EYLISNKVDITLANFTVTDERKKQVDFALPYMKVSLGVVSPKTGLITDVKQLEGKTLI
                     VTKGTTAETYFEKNHPEIKLQKYDQYSDSYQALLDGRGDAFSTDNTEVLAWALENKGF
                     EVGITSLGDPDTIAAAVQKGNQELLDFINKDIEKLGKENFFHKAYEKTLHLTYGDAAK
                     ADDLVVEGGKVD"
     gene            complement(22647..23294)
                     /locus_tag="VQ862_000524"
     CDS             complement(22647..23294)
                     /locus_tag="VQ862_000524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001002414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3114920.1"
                     /translation="MNEIITLKNIQLELKKTCVFQNLNFSCKQGEIIGITGANGSGKS
                     VLFKLIAGLYSPSYGEVLINGENIVPERKIPANLGALIEEPGFINYYSGFKNLQYLAS
                     IRGVVGNQEINDTLKIVGLYEQKDQKVKTYSLGMRKKLGIAQAIMENPSILLLDEPMN
                     ALDKSSVENMRTLFRKLSSEKGTTILIASHSEEDIRILCDKVYAIEDKVCTLCSD"
     gene            complement(23291..23989)
                     /locus_tag="VQ862_000525"
     CDS             complement(23291..23989)
                     /locus_tag="VQ862_000525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3114921.1"
                     /translation="MGKLSSHMWRLNQIIYTKYFWGYVLFWILICLGLWYWLEGNDRL
                     VIEILKGPNLSQNSFLVLSIWLLHWFIIHTFFLAVVYRRRASDFFMEVIRFSSIKLWI
                     RYQIWTCFLYGLILIMVKVLVIQFMLQLPNWDIGVLFIVDSLNACVLVLFCFMLYVLG
                     ANEQMNFSCVSFFLLMIVFGGLFVGNRTNYLFYILNRGNGDIGRDLFLQLLFLVFLFK
                     SIFYFTRQKRRFIE"
     gene            complement(23999..24751)
                     /locus_tag="VQ862_000526"
     CDS             complement(23999..24751)
                     /locus_tag="VQ862_000526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3114922.1"
                     /translation="MKQFVQFYKKDFLAVLVYFILLLSCVLSSTVYLLRCRQYSIHPN
                     VLEWILVLLQDMTTGVYCFPFTYILFFFYLMNNYFNRLECRIRLKSIKHFTSFSFKLA
                     ALSTGIWTATLFLLIFLIAFSNGFSFSLEIKEVDFLREFYGISIANNASFFIGFFFSY
                     IAYYFFLSLLTISSFSWFKKSNMSLVFLFTFLFVESLFWIYQLDNGIIGLLPIFQYMV
                     NSNPYALIYWLTLLSIIIPLTVFSVHRNWRRV"
     gene            complement(24751..25515)
                     /locus_tag="VQ862_000527"
     CDS             complement(24751..25515)
                     /locus_tag="VQ862_000527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000394067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3114923.1"
                     /translation="MEFFICNLVRVVQSPRFYMSLFLTLLCMSLGNFLAFNGIYKIEG
                     LSIFFAASSIRGFSPISLVAALICTLPYSSQIIEDAESHFLTAQLCRISKKRYLAIVG
                     STAIISSFLVFFLPYLLLLGINLLVTPYQEIYIGDYSGALKELFDSNQFLYSLVTTLW
                     YGVWGAVFSIFGLASALLVKKKLGAIFIPVAYMMVGGILWAILGLSYLEPVTTLALGY
                     QKDISLSLVSGHLAFILFVSCLVVYGTFFLHSEDYV"
     gene            complement(25611..26014)
                     /locus_tag="VQ862_000528"
                     /pseudo
     CDS             complement(25611..26014)
                     /locus_tag="VQ862_000528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000829085.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(26194..26826)
                     /locus_tag="VQ862_000529"
     CDS             complement(26194..26826)
                     /locus_tag="VQ862_000529"
                     /EC_number="2.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000170913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotate phosphoribosyltransferase"
                     /protein_id="HET3114924.1"
                     /translation="MTLAKDIASHLLKIQAVYLKPEEPFTWASGIKSPIYTDNRVTLA
                     YPETRTLIENGFVEAIKEAFPEVEVIAGTATAGIPHGAIIADKMDLPFAYIRSKPKDH
                     GAGNQIEGRVAQGQKMVVVEDLISTGGSVLEAVAAAKREGADVLGVVAIFSYQLPKAD
                     KNFADAGVKLVTLSNYSELIHLAQEEGYITPEGLDLLKRFKEDQENWQEG"
     gene            complement(26860..27561)
                     /gene="pyrF"
                     /locus_tag="VQ862_000530"
     CDS             complement(26860..27561)
                     /gene="pyrF"
                     /locus_tag="VQ862_000530"
                     /EC_number="4.1.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001206708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotidine-5'-phosphate decarboxylase"
                     /protein_id="HET3114925.1"
                     /translation="MREHRPIIALDFPSFEAVKEFLALFPAEESLYLKVGMELYYAAG
                     PEIVSYLKGLGHSVFLDLKLHDIPNTVKSAMKVLSQLGVDMTNVHAAGGVEMMKAARE
                     GLGSQAKLIAVTQLTSTSEAQMQEFQNIQTSLQESVIHYAKKTAEAGLDGVVCSAQEV
                     QVIKQATNPDFICLTPGIRPAGVAVGDQKRVMTPADAYQIGSDYIVVGRPITQAEDPV
                     AAYHAIKDEWTQDWN"
     gene            complement(27794..28993)
                     /gene="divIB"
                     /locus_tag="VQ862_000531"
     CDS             complement(27794..28993)
                     /gene="divIB"
                     /locus_tag="VQ862_000531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000031166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein DivIB"
                     /protein_id="HET3114926.1"
                     /translation="MSKDKKNEDKEILEELKELSEWQKRNQEYLKKKAEEEAALAEEK
                     EKERQARMGEESEKSEDKQDQESETDQEDSESAKEESEEKVASSEADKEKEEKEEPES
                     KEKEEQDKKLSKKATKEKPAKAKIPGIHILRAFTILFPSLLLLIVSAYLLSPYATMKD
                     IRVEGTVQTTADDIRQASGIQDSDYTINLLLDKAKYEKQIKSNYWVESAQLVYQFPTK
                     FTIKVKEYDIVAYYISGENHYPILSSGQLETSSVSLNSLPETYLSVLFNDSEQIKVFV
                     SELAQISPELKAAIQKVELAPSKVTSDLIRLTMNDSDEVLVPLSEMSKKLPYYSKIKP
                     QLSEPSVVDMEAGIYSYTVADKLIMEAEEKAKQEAKEAEKKQEEEQKKQEEESNRNQT
                     TQRSSRR"
     gene            complement(29003..30061)
                     /locus_tag="VQ862_000532"
     CDS             complement(29003..30061)
                     /locus_tag="VQ862_000532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000724845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine--N-acetylmuramyl-
                     (pentapeptide) pyrophosphoryl-undecaprenol
                     N-acetylglucosamine transferase"
                     /protein_id="HET3114927.1"
                     /translation="MKKIVFTGGGTVGHVTLNLLLMPKFIEDGWEVHYIGDKRGIEHQ
                     EILKSGLDVTFHSIATGKLRRYFSWQNMLDVFKVCWGIVQSLFIMLRLRPQTLFSKGG
                     FVSVPPVIAARVSGVPVFIHESDLSMGLANKIAYKFATKMYSTFEQASSLSKVEHVGA
                     VTKVSDQKNPEPDELVDIQSHFNHKLPTVLFVGGSAGARVFNQLVTDHKKELTERYNI
                     INLTGDSSLNELSQNLFRVDYVTDLYQPLMELADIVVTRGGANTIFELLAIAKLHVIV
                     PLGREASRGDQLENAAYFVKKGYAEDLQESDLTLDSLEEKLSHLLSHKEDYQAKMKAS
                     KELKSLADFYQLLKKDLS"
     gene            complement(30063..31415)
                     /locus_tag="VQ862_000533"
     CDS             complement(30063..31415)
                     /locus_tag="VQ862_000533"
                     /EC_number="6.3.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000862950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanine--D-glutamate
                     ligase"
                     /protein_id="HET3114928.1"
                     /translation="MKVIDQFKNKKVLVLGLAKSGESAARLLDKLGAIVTVNDGKPFE
                     DNPAAQSLLEEGIKVITGGHPLELLDEEFALMVKNPGIPYNNPMIEKALAKGIPVLTE
                     VELAYLISEAPIIGITGSNGKTTTTTMIGEVLTAAGQHGLLSGNIGYPASQVAQIASD
                     KDTLVMELSSFQLMGVQEFHPEIAVITNLMPTHIDYHGSFSEYVAAKWNIQNKMTAAD
                     FLVLNFNQDLAKDLTSKTEATVVPFSTLEKVDGAYLEDGQLYFRGEVVMAANEIGVPG
                     SHNVENALATIAVAKLRGVDNQTIKETLSAFGGVKHRLQFVDDIKGVKFYNDSKSTNI
                     LATQKALSGFDNSKVVLIAGGLDRGNEFDELVPDITGLKKMVILGQSAERVKRAADKA
                     GVAYVEATDIADATRKAYELATQGDVVLLSPANASWDMYANFEVRGDLFIDTVAELKE
                     "
     gene            complement(31519..32160)
                     /locus_tag="VQ862_000534"
     CDS             complement(31519..32160)
                     /locus_tag="VQ862_000534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000571297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3114929.1"
                     /translation="MIELKNISKKFGSRQLFSDTNLHFEGGKIYALIGTSGCGKTTFL
                     NMIGRLEPYDKGQIIYDGTSLKDIKPSVFFRDYLGYLFQDFGLIESQTVKENLNLGLV
                     GKKLKEKEKISLMKQALNCVNLSYLDLKQPIFELSGGEAQRVALAKIILKDPPLILAD
                     EPTTSLDPKNSEELLSILESLKNPNRTIIIATHNPLIWEQVDQVIRVTDLSHR"
     gene            complement(32162..34182)
                     /locus_tag="VQ862_000535"
                     /pseudo
     CDS             complement(32162..34182)
                     /locus_tag="VQ862_000535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000732428.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
     gene            complement(34253..34552)
                     /locus_tag="VQ862_000536"
     CDS             complement(34253..34552)
                     /locus_tag="VQ862_000536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
                     /protein_id="HET3114930.1"
                     /translation="MKTKKHRLLALALISSFTLLGAASAAVQYPDGGVWTYGEGSGGG
                     WAFSNYYHGKKYHYSSLVSRWNSHSDKGEASAGKTSYAWIWTKWGEQVAFYCDYD"
     gene            complement(34918..35172)
                     /locus_tag="VQ862_000537"
     CDS             complement(34918..35172)
                     /locus_tag="VQ862_000537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000262800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3165 family protein"
                     /protein_id="HET3114931.1"
                     /translation="MVYLVLGILLLLLYVFATPESIKGTVNIVAMVCILVALLILLVL
                     SFLKIFQLPTEIFLAIAMLILAYFSVRDITLMPVKKSKRR"
     gene            complement(35192..37033)
                     /gene="typA"
                     /locus_tag="VQ862_000538"
     CDS             complement(35192..37033)
                     /gene="typA"
                     /locus_tag="VQ862_000538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003078415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translational GTPase TypA"
                     /protein_id="HET3114932.1"
                     /translation="MTKLREDIRNIAIIAHVDHGKTTLVDELLKQSETLDARTELAER
                     AMDSNDIEKERGITILAKNTAVAYNGTRINIMDTPGHADFGGEVERIMKMVDGVVLVV
                     DAYEGTMPQTRFVLKKALEQDLVPIVVVNKIDKPSARPAEVVDEVLELFIELGADDDQ
                     LDFPVVYASAINGTSSLSDDPADQEATMAPIFDTIIDHIPAPVDNSDEPLQFQVSLLD
                     YNDFVGRIGIGRVFRGTVKVGDQVTLSKLDGTTKNFRVTKLFGFFGLERREIQEAKAG
                     DLIAVSGMEDIFVGETITPTDAVEALPILHIDEPTLQMTFLVNNSPFAGKEGKWVTSR
                     KVEERLQAELQTDVSLRVDPTDSPDKWTVSGRGELHLSILIETMRREGYELQVSRPEV
                     IVKEIDGVKCEPFERVQIDTPEEYQGSVIQSLSERKGEMLDMISTGNGQTRLVFLVPA
                     RGLIGYSTEFLSMTRGYGIMNHTFDQYLPLIPGEIGGRHRGALVSIDAGKATTYSIMS
                     IEERGTIFVNPGTEVYEGMIIGENSRENDLTVNITKAKQMTNVRSATKDQTAVIKTPR
                     ILTLEESLEFLNDDEYMEVTPESIRLRKQILNKAEREKANKKKKSAE"
     gene            37195..37920
                     /locus_tag="VQ862_000539"
     CDS             37195..37920
                     /locus_tag="VQ862_000539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001235004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HET3114933.1"
                     /translation="MRLDNLLAQEKVSRKAMKQALLRGEILVDGCPARSLAQNIDTGL
                     QELLFQDRIIQGYEHTYLMLHKPAGVVTANKDKELPTVMDLLPSDIQSDKLYAVGRLD
                     RDTTGLLLLTDNGPLGFQLLHPQYHVDKTYQVEVNGLLTPDHIQTFQKGIVFLDGTIC
                     KPARLEILSASPSLSQASITISEGKFHQIKKMFLSVGVKVTNLKRIQFGDFTLNPDLA
                     EGNYHPLNQKELQIIKNYLEMSR"
     gene            complement(37960..38187)
                     /locus_tag="VQ862_000540"
     CDS             complement(37960..38187)
                     /locus_tag="VQ862_000540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000660075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3114934.1"
                     /translation="MKEKKKNPLFVGILSIILGLLFPIVGLILGIIGLVLAISYQKES
                     QLDYKIEKILNILGIVISVVNWIVAIALIFR"
     gene            complement(38276..38656)
                     /locus_tag="VQ862_000541"
     CDS             complement(38276..38656)
                     /locus_tag="VQ862_000541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HET3114935.1"
                     /translation="MVTWILWALILAMLAWMGFNYLRIRRAAKIVDNEEFEALIRTGQ
                     LIDLRDPAEFHRKHILGARNIPSSQLKTSLAALRKDKPVLLYENQRAQRVTNAALYLK
                     KQGFSEIYILSYGLDSWKGKVKTS"
     gene            complement(38656..38925)
                     /locus_tag="VQ862_000542"
     CDS             complement(38656..38925)
                     /locus_tag="VQ862_000542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000051789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqgQ family protein"
                     /protein_id="HET3114936.1"
                     /translation="MSLFLKKTQNFARMSLMKTFYDVQQFLKRFGIIVYMGKRLYDIE
                     LMKLELSRIYDAGLMDKLDYLEAEAVLRREHKVELDYIEKNGEKN"
     gene            38989..39897
                     /locus_tag="VQ862_000543"
     CDS             38989..39897
                     /locus_tag="VQ862_000543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HET3114937.1"
                     /translation="MRIQQLHYIIKIVETGSMNEAAKQLFITQPSLSNAVRDLENEMG
                     IEIFIRNPKGITLTRDGMEFLSYARQVVEQTQLLEERYKNPVAHRELFSVSSQHYAFV
                     VNAFVSLLKKSDMEKYELFLRETRTWEIIDDVKNFRSEVGVLFLNSYNRDVLTKMLDD
                     NHLLAHHLFTAQPHIFVSKTNPLAKKDKVKLSDLENFPYLSYDQGTHNSFYFSEEILS
                     QEHHKKSIVVSDRATLFNLLIGLDGYTIATGILNSNLNGDNIVSIPLDIDDPIELVYI
                     QHEKTSLSKMGERFIDYLLEEVQFDS"
     gene            complement(39951..40706)
                     /locus_tag="VQ862_000544"
     CDS             complement(39951..40706)
                     /locus_tag="VQ862_000544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001142149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HET3114938.1"
                     /translation="MPTILITGASGGLAQEMVKLLPNDQLILLGRNKEKLAQLYGNYS
                     HAELIEIDITDDSALEALVTDLYLRYGKIDVLINNAGYGIFEGFDQIADKDIHQMFEV
                     NTFALMNLSRHLAARMKESSKGHIINIVSMAGLIATGKSSLYSATKFAAIGFSNALRL
                     ELMPYGVYVTTVNPGPIRTGFFDQADPDGTYLKSVDRFLLEADAVAKKIVKIIGKNKR
                     ELNLPILLNLAHKFYTLFPKLADKLAGETFNYK"
     gene            complement(40727..41656)
                     /locus_tag="VQ862_000545"
     CDS             complement(40727..41656)
                     /locus_tag="VQ862_000545"
                     /EC_number="3.1.26.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000354350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Z"
                     /protein_id="HET3114939.1"
                     /translation="MDIQFLGTGAGQPSKARNVSSLALKLLDEINEVWLFDCGEGTQN
                     RILETTIRPRKVSKIFITHLHGDHIFGLPGFLSSRAFQANEEQTDLEIYGPQGIKSFV
                     LTSLRVSGSRLPYRIHFHEFDQDSLGKILETDKFTVYAEELDHTIFCVGYRVMQKDLE
                     GTLDAEKLKAAGVPFGPLFGKIKNGQDLVLEDGTEIKAADYISAPRPGKIITILGDTR
                     KTDASVRLAVNADVLVHESTYGKGDEKIARNHGHSTNMQAAQVAVEAGAKRLLLNHIS
                     ARFLSKDISKLKKDAATIFENVHVVKDLEEVEI"
     gene            complement(41671..42294)
                     /locus_tag="VQ862_000546"
     CDS             complement(41671..42294)
                     /locus_tag="VQ862_000546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine beta-lyase"
                     /protein_id="HET3114940.1"
                     /translation="MTDIKTLALKYGGYTSLDKVYLDQLLAGKTEQEQLTLITPPPSV
                     VNAYFAELYQKKSPQAATDYFAELSQELNLYNTEPSFTLENKPFIRLNLSGKSFGFCY
                     ESDGLGRIFSENEEKISDDLLFEIAQIFSHQLVFEESGKIYMKPVKDEEVVSLESLTA
                     LTDLERLADGRKRLKGYSQEDLLQEAAAFSGKRYFRSENRTAMLYID"
     gene            complement(42287..43525)
                     /gene="hflX"
                     /locus_tag="VQ862_000547"
     CDS             complement(42287..43525)
                     /gene="hflX"
                     /locus_tag="VQ862_000547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000573186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase HflX"
                     /protein_id="HET3114941.1"
                     /translation="MIETEKKEERVLLIGVELQGMDSFDLSMEELASLAKTAGAVVVD
                     SYRQKREKYDSKTFVGSGKLEEIALMVDAEEITTVIVNNRLTPRQNVNLEEVLGVKVI
                     DRMQLILDIFAMRARSHEGKLQVHLAQLKYLLPRLVGQGIMLSRQAGGIGSRGPGESQ
                     LELNRRSVRNQITDIERQLKVVEKNRATVREKRLESSTFKIGLIGYTNAGKSTIMNIL
                     TSKTQYEADELFATLDATTKSIHLGGNLQVTLTDTVGFIQDLPTELVSSFKSTLEESK
                     HVDLLVHVIDASNPYHEEHEKTVLSIMKDLDMEDIPHLTLYNKADLVEDFTPTQTPYT
                     LISAKSEDSRENLQALLLDKIKEIFEAFTLRVPFSKSYKIHDLESVAILEERDYQEDG
                     EVITGYISEKNKWRLEEFYD"
     gene            complement(43518..44402)
                     /gene="miaA"
                     /locus_tag="VQ862_000548"
     CDS             complement(43518..44402)
                     /gene="miaA"
                     /locus_tag="VQ862_000548"
                     /EC_number="2.5.1.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenosine(37)-N6)-dimethylallyltransferase
                     MiaA"
                     /protein_id="HET3114942.1"
                     /translation="MKTKIIVIVGPTAVGKTALAIEVAKCFNGEVVSGDSQQVYRGLD
                     IGTAKASPEEQAAVPHHLIDVREITESYSAFDFVSEAKMTIEDIHSRGKLAIIAGGTG
                     LYIQSLLEGYHLGGETPHEEILAYRASLEPYSDEELAHLVEQAGLEIPQFNRRRAMRA
                     LEIAHFGQDLENQEILYEPLIICLDDERSQLYERINHRVDLMFEAGLLDEAKWLFDHS
                     PNVQAAKGIGYKELFPYFRGEQTFEEARESLKQATRRFAKRQLTWFRNRMQVTFYQIG
                     ESGVQDRILSQIEEFLDD"
     gene            44523..44693
                     /locus_tag="VQ862_000549"
     CDS             44523..44693
                     /locus_tag="VQ862_000549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001051775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3042 family protein"
                     /protein_id="HET3114943.1"
                     /translation="MAKGFAKGLVTGVAGTVAAVAGAVYAFKKKVIEPEEQKAAFIEE
                     NRKKAARRRVSR"
     gene            complement(44741..45580)
                     /locus_tag="VQ862_000550"
     CDS             complement(44741..45580)
                     /locus_tag="VQ862_000550"
                     /EC_number="2.1.1.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003011065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate synthase"
                     /protein_id="HET3114944.1"
                     /translation="MTKADTIFKENIERILKEGVFSEQARPKYKDGTVANSKYVTGAF
                     SEYDLSKGEFPITTLRPIAIKSAIKEVLWIYQDQSNSLEVLNDKYNVHYWNDWEVGDT
                     GTIGERYGAVVKKHDIINKLLKQLETNPWNRRNIISLWDYQAFEETDGLLPCAFQTMF
                     DVRRVDGEIYLDATLTQRSNDMLVAHHINAMQYVALQMMIAKHFGWKVGKFFYFINNL
                     HIYDNQFEQAQELLRREPSNCQPRLVLNVPDGTNFFDIKAEDFELVDYDPVKPQLKFD
                     LAI"
     gene            complement(45677..46636)
                     /locus_tag="VQ862_000551"
     CDS             complement(45677..46636)
                     /locus_tag="VQ862_000551"
                     /EC_number="2.7.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002919069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family glucokinase"
                     /protein_id="HET3114945.1"
                     /translation="MSQKIIGIDLGGTSIKFAILTTAGEIQGKWSIKTNILDEGSHIV
                     DDMIESIQHRLDLLGLAAADFQGIGMGSPGVVDREKGTVIGAYNLNWKTLQPIKQKIE
                     KALGIPFFIDNDANVAALGERWMGAGDNQPDVVFMTLGTGVGGGIVAEGKLLHGVAGA
                     AGELGHITVDFDQPISCTCGKKGCLETVASATGIVNLTRRYADEYEGDAALKRLIDNG
                     EEVTAKTVFDLAKEGDDLALIVYRNFSRYLGIACANIGSILNPSTIVIGGGVSAAGEF
                     LLQGVQKVYDENSFPQVRTSTKLALATLGNDAGVIGAASLVLQ"
     gene            complement(46763..47760)
                     /locus_tag="VQ862_000552"
                     /pseudo
     CDS             complement(46763..47760)
                     /locus_tag="VQ862_000552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042519.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
     gene            complement(47810..48427)
                     /locus_tag="VQ862_000553"
     CDS             complement(47810..48427)
                     /locus_tag="VQ862_000553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000766583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HET3114946.1"
                     /translation="MKLIFLHGLGQSAESWKEVRNLLTDYPSEAIELFPSGVSNYQQA
                     KERVYQHLAQETEPFVLIGLSLGAALALELSSYDLPNLRALILSGCPLKLAGNILFYL
                     QLLIFKLLPKRVFEKQGADKALMVGVSEELKTLDLTDIAGTCPYPTLLICGIKDKPNL
                     SSMRSLHKLISESQFQIIPDGPHVLNKAKPKEFVEKTRSFLELLK"
     gene            complement(48428..50149)
                     /gene="pabB"
                     /locus_tag="VQ862_000554"
     CDS             complement(48428..50149)
                     /gene="pabB"
                     /locus_tag="VQ862_000554"
                     /EC_number="2.6.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate synthase component I"
                     /protein_id="HET3114947.1"
                     /translation="MHRKTVIDFRILGERYTFTQPIKEIKTRNVAEVADLLAQVESYQ
                     EQGYYVVGYVSYEAAPAFEEKLAVHKDPLLGEYLLYFTVHDRVETSPIPLTYEDIDLP
                     SNWQEVTSAADYEKAIAQIHHHLRQGDTYQVNYTVQLKQKLSANPFAIYNRMVVEQEA
                     GYNAYVEHDEMAVISMSPELFFEQNDRELTTRPMKGTTQRGVTDQEDLEQASWLEQDP
                     KNRSENMMIVDLLRNDMNRISEVGSEHVERLCQVEQYSTVWQMTSTIKSQLREDVDLV
                     EIFRSLFPCGSITGAPKIATMEIIKDLEPQPRGVYCGTIGLLLPNGRRIFNVAIRTIQ
                     LHKGQAIYGVGGGITWDSTWESEYREVHQKAAVLYRKQARFQLITTGEISQKNLLFED
                     QHLERLRKASRYFAFPFDAEDLGHKIEEECQDCEANQDYRLRISLSKSGEIEVNRQVL
                     TPLSTSFCQAQVCLQEAALNQSFTYFKTTHRPHLSLGEQEKIYHNKSGKLLETSIGNL
                     VLKIAGKLYTPPIRLGILPGIYRQYLLETGQVEEKVLTLADLAQAEAIYGCNAVRGLY
                     ELSLEEN"
     gene            complement(50210..55852)
                     /locus_tag="VQ862_000555"
     CDS             complement(50210..55852)
                     /locus_tag="VQ862_000555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000472960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HET3114948.1"
                     /translation="MFKKDRFSIRKIKGVVGSVFLGSLLMAPSVVDAATYHYVNKEII
                     SQEAKDLIQTGKPDRNEVVYGLVYQKDQFPQTGTEASVLTAFGLLTVGSLLLIYKRKK
                     IASVFLVGAMGLVVLPSAGAVDPVATLALASREGVVEMDGYRYVGYLSGDILKTLGLD
                     TVLEETSAKPGEVTVVEVETPQSTTNQEQARTENQVVETEEAPKEEAPKTEESPKEEP
                     KSEVKPTDDTLPKVEEGKEDSAEPAPVEEVGGEVESKPEEKVAVKPESQPSDKPAEES
                     KVEPPVEQAKVPEQPVQPTQAEQPSTPKESSQQENPKEDRGAEETPKQEDEQPAEAPE
                     IKVEEPVESKEETKTAKGTQEKGHVGEALAQEQLPEYKVTEGTLVETSTTDLDYKTET
                     TEDPTKYTDEETVLRTGEKGSQVTKTTYKTVEGVKTDQVLSTSTEVTKEPVNQQVIRG
                     TKPIEGTLIEESLEKIPFKEVVKEDDQLKKGLEVVAQEGKEGQKKITKTFNTIKGVKT
                     EDAPKVTEEILEEPQDKILKRGTKSFEKPVLTITEIESKDLKRTSDVKYSLENPSKAA
                     IKSITLTLKKGDEIVKTLNVSPEDLTTTLTDLQYYKDYKLETKMVYDRGEGDEEEVLK
                     EEPLRIDLKKVEIKDIIRTDLIKYENQVETDETRLTSVPTDLSNYYLKVTSNDHKTNL
                     LAVQKIEESTIDGKQVYKVIAVADNLVQRNVDNRFEETYTYYIEKPKASQAGIFYDFE
                     ELIQAIQTNPAGEFKLGQSMSARNVVPKGKSYITSEFTGKLLSDGDKRYAIHNLEHPL
                     FDKIKAGTVKNINFENIDIDLSNQDNIAAIANEISGTTRIENIKAIGTITARNNVAGF
                     VNNIKEDATLENVAFIGSINSAGNNSTVGGIAGSNYMGFVNRAYVDATITANNANASM
                     LVPFVQYKAHSWLSGTKGKLTNSVAKGILDVKNTKYVGGITSKTWPYGAVQDNVTYAK
                     VIKGQEIFGSNDVNDGDANPFVSNLFGVIGYSSSEDGTGKDNKNKNKLKHLSKSEADA
                     KVASFNITAAKFVSEPYELNKLNNVSSREAAYESIQDYNADYKLAYKNIEKLQPFYNK
                     DFIVNQANKLDKNNKLNTKEILSVTPMNNNNFVTDLGDANKIIVHYADGTKDYFNLSS
                     SDEGLSNVREYTITDLGIKYTPNIVQKDHSALINGIVNILSPIELQSNPIYQKLGRTG
                     SNRVNAIKDLYLEESFDHVKANLNILVTKLVENEDHQLNNSSAAQQMILDKVEKNKAA
                     LLLGLTYLNRYYGVKFGDVNIKELMLFKPDFYGKNVSVLDRLIEIGSREDNIKGHRTY
                     DAFSEIISKTTLSENLVNFLNYNRRLFTADVNIYDWFKKATEGNVYIAERASEVDEIK
                     AAKYKVWDNLQSATHRKMILPLLNLNKSHVYLISNYSAMAVGTAEKLGHSSFDGIKNQ
                     IEKAADSYRNYFDFWYRLSLDKVKNMLVKNTVTPLWEGYQAPGGWPDKYGKRNNKEDY
                     APLRELFGPIGKYYGNNGTGAYAVIWDNPLDTRTEVNYIALSMIDEFGISVYTHETTH
                     VNDRAIYLGGYGRRSGTHAEAYAQGMLQTPVPSTWFDEYGALGINMTFYRPNDGNQWY
                     ITDPKTLKTREDIDNYMKGYIDTLSLLDYVEGDAVISKHDDKLNQLWFKKVDPIERTV
                     GSKDQYDKVRNMSSDDWKGITLNSVNDLVDNNLMTNRMMNNNIYKPEVFDPGIAYVGI
                     KMMNSIYAGNTSEGAPGAVTFKNNAFRLWGYYGYDKGFLGYASDKLKSQANKEGKQFG
                     DQYIIQKISDGRFQSFADFKKEYYKELLEKANAGFTPFTIDGETIHNYDELKSLFAKA
                     LEEDMVTNKVNGKLVQVKEKVYKKLLQQTNSFKTSIFK"
     gene            complement(55874..56437)
                     /locus_tag="VQ862_000556"
     CDS             complement(55874..56437)
                     /locus_tag="VQ862_000556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01440 family protein"
                     /protein_id="HET3114949.1"
                     /translation="MNETQIQRETRQVVEDVLEKTNLKQGVLFVLGLSSSEVLGGQIG
                     KESSQEIGELIVETILGILGSRGIHLAVQGCEHVNRALVVERQVAEQFDLEIVSVHPT
                     LHAGGSGQLAAFKFMQDPVEVEFIKAHAGLDIGDTAIGMHVKHVQVPIRPILREIGHA
                     HVTALASRPKLIGGARAHYPQDAIRKS"
     gene            complement(56553..58244)
                     /locus_tag="VQ862_000557"
     CDS             complement(56553..58244)
                     /locus_tag="VQ862_000557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HET3114950.1"
                     /translation="MKRSSLLVRMVISIFLVFLILLALVGTFYYQSSSSAIEATIEGN
                     SQTTISQTSHFIQSYIKKLETTSTGLTQQTDVLAYAENPSQDKVEGIRDLFLTILKSD
                     KDLKTVVLVTKSGQVISTDDSVQMKTSSDMMAEDWYQKAIHQGAMPVLTPARKSDSQW
                     VISVTQELVDAKGANLGVLRLDISYETLEAYLNQLQLGQQGFAFIINENHEFVYHPQH
                     TVYSSSSKMEAMKPYIETGQGYTPGHKSYVSQEKIAGTDWTVLGVSSLEKLDQVRSQL
                     LWTLLGASVTSLLVCLCLVWFSLKRWIAPLKDLRETMLEIASGAQNLRAKEVGAYELR
                     EVTRQFNAMLDQIDQLMVAIRSQEETTRQYQLQALSSQINPHFLYNTLDTIIWMAEFH
                     DSQRVVQVTKSLATYFRLALNQGKDLICLSDEINHVRQYLFIQKQRYGDKLEYEINEN
                     VAFDNLVLPKLVLQPLVENALYHGIKEKEGQGHIKLSVQKQDSGLVIRIEDDGVGFQD
                     AGDSSQSQLKRGGVGLQNVDQRLKLHFGANYQMKIDSRPQKGTKVEIYINRIETS"
     gene            complement(58241..58978)
                     /locus_tag="VQ862_000558"
     CDS             complement(58241..58978)
                     /locus_tag="VQ862_000558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET3114951.1"
                     /translation="MTYTILIVEDEYLVRQGLTKLVNVAAYDMEIIGQAENGRQAWEL
                     IQKQVPDIILTDINMPHLNGIQLASLVRETYPQVHLVFLTGYDDFDYALSAVKLGVDD
                     YLLKPFSRQDIEEMLGKIKQKLDKEEKEEQLQDLLTNRFEGNMAQKIQSHLADSQFSL
                     KSLASDLGFSPTYLSSLIKKELGLPFQDYLVRERVKQAKLLLLTTDLKIYEIAEKVGF
                     EDMNYFTQRFKQIAGVTPRQFKKGEDR"
BASE COUNT        17505 a        12978 c        10674 g        17966 t
ORIGIN      
        1 ttgaacaagt gttgaaagag attcgtaaac gtggatttaa gaataaagcc tttcgaactt
       61 tggaagatgt catgaatcaa cttcaagatg tcatacaagg actggagaag gaggtgataa
      121 agtccatcgt taatcggaga tggactagaa tgctttttga aagcagatga gtattatatg
      181 caatttcttt atataaaaag accggattgc tccgatcttt caatagttca tattctcaat
      241 ttctatttta aaaatagcta aggttaacgt caaatgacta cgcgacctat ttcatacgat
      301 aaaaatcaag cactagacca gcaggtcctt gaactaataa ggactctgtt ccccaatcgg
      361 ttacagttgg tccgtgtaaa acctttatac caagctcgtt caaccgtttg tagttctggt
      421 ctacatcctc aacctcgata tgaataatga ttcctgactg aaagttttcc aaaggaacca
      481 aatgattttg tgacaacata aggcagtgac taccaatcgt aaactgagca aaaccatcat
      541 cagcataatc tgccttttta tccaagatat gctccaagtc agcacagact tggggaacat
      601 ttgaaacgat aatatctaat tgatttaaat tcatttactc tcctccataa aaagaccgga
      661 ttgctccgat cttttaaagt tctgctctat gaaaatcaaa gaataaagtc tacaagtttc
      721 atatttgatt ttcggcgaga ggaattattt aattgcgcgt gattgcaatc cttcttcttc
      781 caagaagaga cggaatggta cgagttcttc tgcttcgtat ttttccttga aggctttgat
      841 agcttcttct gagtgaagtt ttggatccaa ttcaagtact tctactggaa gtggacggtg
      901 ttgagtgatg cgagcatcga tgacaacagt tttaccttct ttgttcaatt taacagcttc
      961 tgcaacaact gcatcgatgt cttcgatacg gtcaactgtg aatccaacag ctccttgagc
     1021 ttccgcaatt ttagcgtagt cagcgtttgt gaagtctaca ccaaacaagt gtttgtttgt
     1081 atcttcgtat ttgttcttga tgaagccgta ctcagcattt gagaagacaa ggttgataac
     1141 tggaaggtcg tattgaacgt ttgtgataac gtctgggtag cacatgttga atgctccgtc
     1201 acccatgatg ttccatactt ggcgatctgg attgtctttc ttagcagcga taccaccagg
     1261 aagggcaata cccattgtcg caaagagtgg agatgtacgc cacatgttct taggtgtcat
     1321 gtgaaggtga cgagtagatg tttgagtagt gttacctacg tcgattgagt agatagcgtc
     1381 ttgatcagca tgtttgttga ttgcattgta aacttgatac aattgcaatt caccctcagt
     1441 tttaccttcg agtttgttca tgtaatcacg ccagttttga ttgttcttaa cgtttgcacg
     1501 ccaccatgga gttgattcaa ctgggtttac tttgtcaagg atagctttag ctgcttgacc
     1561 agcatcacca aggattgaag cgtcaagggc atgacgttta ccaagtttgt aagggtcgat
     1621 atcgacttgg atgaattttt cagtgttctt gaatgcttcg taaacttcag cgaatgggaa
     1681 gtttgaacca aggaaaagaa ctgtgtctgc ttcaaagacc acttcgttgg ctggtttcca
     1741 accaacacgg taagcagaac ctgtcaaacc ttcatagttc cattcgaaag cttcaaagtt
     1801 tttaccagtt gtgatgattg gtgctttgat tttacgtgac aattcagtaa tcacttcacc
     1861 agctttaaca ccaccaaatc cagcatagat aactgggcgt tcagcattgt tcaagatttc
     1921 aacagctttg tcgatttcaa cttcgttcaa agcaggagcg atgaatgagc gttcgtatga
     1981 acctgaaccg tagtatgagt tttcatcgat ttcttggaaa ccgaagttta ctggaatttc
     2041 aacaacagct ggaccttttt tagaaactgc agcacggcag gcttcgtcaa ttacttttgg
     2101 caattgctca gcgtaagcta cacgtttgtt gtaaacagcg ataccgttgt acattgggtt
     2161 ttggttaagc tcttggaaag catccatgtt caattcgtta actggacgtg atccaaggat
     2221 cgctaggaat ggagtgttat ccatagctgc atcgtaaaca ccgttaatca agtgagtcgc
     2281 acctggacca cctgaaccaa ctgcaacccc gattgagccg ccgaatttag cttgcataac
     2341 cgctgcaaga gcacctgtct cttcgtggcg aacttgtaag aaacggatat ctttgtcttc
     2401 agccaaagca tccatcaatg agctgagtgt tcctgatggg ataccgtaga ttgtatctac
     2461 gccccatgtt ttcaatacgt taagcattgc tgcagatgca gtaattttcc cttgagtcat
     2521 aatgataact ctccttcaat ttttttaaac ttggagaata cgattacata gaattggaaa
     2581 cgttctccaa atttttacta ttccactgta tcatatttat gctgactttt ctaaaaatct
     2641 gctcaaaact ctctattctc tattctaata cagttttgaa agtgttgtca tttctgtttt
     2701 ataacaaaga aatctagtca ttacttttag tctattttac taaaatttaa cagaagggaa
     2761 ctggtcagaa cagatacaga actaaaggcc atggctagac ctgccaattc tgggttgaga
     2821 gccagtccaa cacctgaaaa gactcctgct gcaatcggaa ttccgacaac attgtagata
     2881 aaagcccaga aaagattgag tagaattcga tgaaaggttt tcttactcat atcaaaggca
     2941 cgaaccactc ctaaaagatt attggttgtc aacaccaaat ctgctgactc gatggcgata
     3001 tctgttccag ctcccatagc aatccccaca tctgctacac taagggcagg agcgtcattg
     3061 ataccgtccc caacaaaggc tactttccct gactgttgca gtttatggat ttcatgggct
     3121 ttttcttctg gcaagacgcc tgcaatgacc tcttcaattc cgatttgatc tgcaatagca
     3181 cgcgccacac cagcattgtc tcctgtcagc atgactgttc ggagaccacg tttttttagc
     3241 tgactgatga ctagcttagc attttcctta ggaatatctt gcaaagcaag caagcctttg
     3301 atttcattgt caacagctaa gaacacaact gtcttagctt ctttttctag ttcttctagt
     3361 ttatcttgat aagtattaga aatatccatg ccatccagca ttttagcatt tccaagtaaa
     3421 acttgttttc cattgattcg ccctgaaaca cctttcccgt gcaaggcctg aaaattttca
     3481 acagtttgaa actcaagtcc agcttcactc gctcgcttaa cgatagcctc agccagtggg
     3541 tgttgagaag catcttccaa ggaggctgcc aatccaaaca cttctacttc gtcgccgatg
     3601 atatctgtta ccacaggttt cccttccgtc aaagtcccgg tcttatcaaa gacaagagtt
     3661 tgaactttct ggatttcctg taagacagtt ccatttttga ggagaacccc catcttggca
     3721 ctacgtcctg tccccaccat aagggctgtc ggtgttgcaa gtcccaaggc acaaggacag
     3781 gcgataatca aaaccgccac tccgtagaga agagaggaca caaagctagc tccaagcacg
     3841 accacactat ccctgagcaa gacgaaccaa acccaaaagg tcatgattcc taaaatgaca
     3901 actactggga caaaaatccc tgaaatctta tccgtcaagt cctgaatcgg cgcacgactt
     3961 gtctgagctt tcttcacaaa atccacaatc tgagccaaaa cagtctctga gccaactttt
     4021 tctgctctaa agacaagcgt tccactatga ttgatggttg agccaatgac agtatctcca
     4081 actgtcttgt ccacaggcag actctcacct gtcaccatgg attcgtcaat actagagaca
     4141 ccttctacta cgacaccatc aacagcaatc ttttcaccgg gacgcactcg aatcaggtcg
     4201 cctaccttga cttgttccaa aggaacttgg acataactat catcactcaa gacttctgcg
     4261 gttttagctt gcaagtccag taatttctcc acagcttggg acgtattttt tctcattttt
     4321 tcctcaaaaa ctgctcccaa aagaacgaaa aagaggataa atccagcact ttcgaagtaa
     4381 acagggagac cagcaaagag agcaactagg ctatagaaat aagccactag agttcccagc
     4441 gcaaccaagg tatccatgtt ggcattgtgc tttttaaaac tggcccaagc actctggata
     4501 tatggcttac ctgcaactaa cataataggc gttgttgcta gaaaggttcc ccaatgcatg
     4561 acttgatgac taatgctacc tgtcaacatc ccaatcatga gaatcacaag aggcacagta
     4621 aagatactag taatccaaaa acgttgcagg agagatagag attttcgagt cttctcaacg
     4681 actatatagc ttcccttttg catcttcatg ccacaagaaa attcatgtcg ccctaattct
     4741 tgaggtgtaa aacgaatgac tttctcctca tctacgccga ttggttccaa gataccttct
     4801 tcttcaaaca gaatttcctt ataacagttt gaaggagtag cacgatgaaa ggtaatctca
     4861 gctggaattc ccttttgaag ctggatatgg gctggatgat agcctttttc agctcggata
     4921 cggatttttt gaatgccatt ttctaagctt gctttcacaa tttctgtcat agtctccacc
     4981 tactctacaa tcatcttgcc gtgcatcatg ttcataccac aagcaaagcc aaactctcca
     5041 acctgctcag gcgtgatttc cactacatac tcttccccca ttggcaggtt cgcatgtaca
     5101 ccaaaatctg gaaaaacaat ttgatccaga catggtgaag gatccttgcg gtcaaagaca
     5161 atgcgtgctg gcactgattt cttgaggaca atcaactcag gagtatagcc tcccatgact
     5221 tccactcgaa tctcttggta tccgtttttt tgctgggctt tttgtccaga tttttcaggc
     5281 tttttgaaaa accaaaacaa gataaacgcg ataagggcaa tacaaataat ggttacaata
     5341 ctatttaaca tggcgtctcc tttacataca attacatctt acttctgtta cagcacttga
     5401 tttcttctct gaaatcacag cttccaagtc ttccaagtca gtctgagtaa attcacattc
     5461 tacaatcaag tcagccaaca aattcctaat cctacgggaa caaaccttgt ctttgatatc
     5521 ttggacaagt aaatcccgac tttggtctag agttaaaagc gctgaataaa caaaggactt
     5581 gccttctttt ttccgagtca gacactcttt ctcaaccaaa cgagccaaaa gagtttgaat
     5641 ggtcgacttg gaccagtcga accgctctgc caaaacccta atcaaatctg tactggtctg
     5701 ctccccctgc atccaaataa tcttcatgac ctgccattct gcatctgaaa tctgcattac
     5761 catacctcca aaatctacat ttgtcaatta cactcatcag tatactctta aaatctacat
     5821 ttgtcaatta tagaaataat attttcttcg aaaaatagaa ttttaatcat ttgaaaaacg
     5881 atttgcagtc aaatattact atataaacaa taaaaatatg ctatactaaa gaaaaaagaa
     5941 aacaaccact aggggtgcgt aaagctgaga ttaacgactg ttagatccct ctgactcaat
     6001 ctaggtaatg ctagctgatg gaagtggaaa tgataatggg gactagcagt cttctattgc
     6061 ctttctaaaa cagactagct tgttcttaag aatacaaact tcagttggtt gggaggtttt
     6121 agatgactta tttacccgtt gctttgacca ttgcagggac tgaccctagt ggtggtgctg
     6181 gcattatggc agatttaaag tcattccaag cgagagatgt ctatggaatg gctgttgtaa
     6241 ccagtcttgt cgctcaaaat accagaggtg ttcagctaat cgagcacgtt tctcctcaaa
     6301 tgttgaaagc ccaattggag agtgtctttt ctgatattcc acctcaggct gtaaaaactg
     6361 gaatgttggc tactactgaa atcatggaaa tcatccaacc ctatcttaaa aaactggatt
     6421 gtccctatgt ccttgatcct gttatggttg ctacaagtgg agatgccttg attgactcaa
     6481 gtgctagaga ctatctcaaa acaaacttac tacctctagc aactattatt acgccaaatc
     6541 ttcctgaagc agaagagatt gttggttttt caatccatga ccccgaaggc atgcagcgtg
     6601 ctggtcgcct gattttaaaa gaatttggtc ctcagtctgt ggttatcaaa ggcggacatc
     6661 tcaaaggtgg tgctaaagat ttcctcttta ccaagaatga acaatttgtc tgggaaagcc
     6721 cacgaattca aacctgtcac acccatggta ctggatgtac ctttgctgca gtgattactg
     6781 ctgaactagc caagggcaag agtctttacc aggcagttga taaggccaag gcctttatca
     6841 caaaagctat tcaagatgcc cctcaactcg gtcatggttc tggtccagtc aaccatacaa
     6901 cttttaaaga ttaagaaaaa aactctctag ttcccacttt aagggaatta gagagttttt
     6961 atactcttcg aaaatctctt caaactacgt cagcttccat ctgcaacctc aaaacactgt
     7021 tttgagctga cttcgtcagt cttatctaaa acctcaaggc agtactttga gcaacctgcg
     7081 actagctttc tagtttactc tttgattttc attgagtatt aattaggaaa gaatgtcatg
     7141 caactttgtt aaaaaggctt gcgtttttgc ctcaatatct tctgcttgca tcaaatcacg
     7201 tacaacagct acaccagcta tgccagtgcc cataagctga tcaatattct ccgaagtcaa
     7261 gcctccaata gcaactactg gaatggcaac cgtttggcaa attgttttca aggtcgatat
     7321 cagagtaatg ggcgcatttt ccttggtggt ggttgggaaa atggctcctg tacccaagta
     7381 atctgcacct gatttctccg cttccagagc tcttttaacc gttttagcgg tgacaccgag
     7441 gattttttca ggacccaaga ctttgcgagc taccgaaact ggtaattcat catctccgat
     7501 atgcagacct gctgcatcaa ccgcaagaca aacatccaac cgatcatcga ttatcaaggg
     7561 gacctgatag gcatctgtta tttccttgac ttgttttgcc agttgataat attgattggt
     7621 tgtgagattt ttttctcgca attggactat ggtaacccct gaacggcagg ccgtctcaac
     7681 ttttgcaaga aagctttcca cggaatcttg atagcgattg gttaccagat atagtctaag
     7741 tgcttctcta ttcataaacc tctcctttga tggtatctag ccaattttca tctcttctta
     7801 ggagcgaaag ctgattgagt acttggtaac gaaattcttc caatcccatt ccttgaacaa
     7861 ctattttctc agcagcgata ttgagataag agactgctaa gcaagaagct tcaaaaccag
     7921 tctttccttg gctgagaaaa acggctgtta aggctccaac caagtctcct gtccctgtta
     7981 tccagtctaa ttcagtacag ccattctcca gtacagcaac ttgattctcc gaaacaataa
     8041 ggtccttggg gccagtaact aagaaagaca taccaggata ggtctgacac cagtctttca
     8101 agacttgaag caaatcctcc gtttcttgat ctttagcact cgcatcgacc ccaacgccgt
     8161 ggtgctttaa tccaacaaga cttcgaattt ctgacatgtt tcctttaagg accgtaggtc
     8221 tatagtctaa aaggtcttta actaagctct tacgaatgga tgaagtcgtt acgccaaccg
     8281 catctactac catcgggaga gaagattggt ttgcatacga agctgccatg cggattgctt
     8341 tttccttctc agctgacaaa tgccccaaat tgatgaagag agcctgactt tgcttagtaa
     8401 aatcaagaac ttcacgggga tcatctgcca tgacaggttt gcatcccaga gccaaaatcc
     8461 catttgccag catctcacaa gaaatctcat tggtcataca gtgaatgagg gaactagagc
     8521 ctataggaaa aggatttgtc aatgcctgca tcattctatc ctttcagcaa agaaatatcc
     8581 ttgcactttt ttaaagaatt cctgcttgat taaaaatcta aatgcaataa aggaaatcgc
     8641 tgtaccaatc aaggttgctc cgaaaaatcg aggagtgtag ataaaccaac taagcttagc
     8701 agccgatcct gtaaagagca ccataacagg ataggaaaca atagaaccaa taatacctgt
     8761 tcccacaatt tctcccaagg cagaaaagta aaattttcga ccgtacttat aaaagagacc
     8821 tgctagaagg gctccaaaag tcgctcctgt gagagctaaa ggcggaatcc cttgagtcgt
     8881 catacggata aaggctgtca ctgtagccat agccaaggca taaacaggtc ccatcatgat
     8941 tcccgctaga atattgacta cactggacat cggtgccatt ccctcaatcc gaaagatagg
     9001 tgtaaggact acatcaaggg caatcatcat agataaaatg gtcaatttgt gaacttgtag
     9061 ttggtgcttt ctcatgtttc tattcttctc ctttttctaa agactgtaaa tcgctcttcc
     9121 atgtctggtg ttggtaagcc atctcccaaa acttagcttc catatgaaca ctgatgtgga
     9181 aggcatctag cattttttgc ttatctgtct catcactttc tcgataaagc tgattgacca
     9241 gtgctccctc ctctctgatc tgttgctcta actcatccgt aatataagtt tcaatccatt
     9301 gttgatagag aggatttggt gatggtttaa gattaagtga tttgcctata tcatggtata
     9361 accaaggaca aggaagcaag cttgcaaaag ctatggctaa gttcggttct gcaaattgcc
     9421 tataaatatg agaaatgtaa tgataacagg ttggagcgat tggatgttgc tccatttcct
     9481 ggtcgttgat ttccaattcc ttgaaaaatt gttggcgaat aaataactca ccctccacta
     9541 aaccctgagc attttgtttc aagagtcttt tcatctcttg gtttgaagtc ttatcagcca
     9601 aaagatgata gatttctgag aaagccttca gatagtaggc atcctgaatc aggtaatagc
     9661 ggaaaatggc aggttctaaa ttcccctctt gtaattgtaa aataaaggga tgatgaaagg
     9721 aagcctgcca agctttcttg gataattcca tcgcaatatc tgtaaattcc ataataactc
     9781 ctttataaaa atagactggt ttgaagcaat aaaaagaaaa gcaggtagat taattttgtt
     9841 tttttaggaa tataaaaagt ccgatagcta ttcttcaact gtgcatgttc gtcatatccg
     9901 tgagcagata gagctctcag gtaaagatgg cgccacctaa agactgtcat cagaacctta
     9961 ctgtaaatca agggcgacca aaaatgtagt ttttgaccac gtaataggca agcttctttg
    10021 agggacttga tttcttgctg aatgagagga aaagaattga ataccacaat caaggcatag
    10081 gaccaagagc gtgatagccc cttttgagcc aagtacaaga gaagctcttt tagtgaaata
    10141 gaggaaacaa agacaaggcc gatacaaact gtcacaaagg ccctcgttcc aagcatgact
    10201 gcctgtgaag catctccgtg taactgaact gcccagtagt tggcaaaaga tggtaaaatg
    10261 gcaagtatga tcatccaagc taacatttta aatcgacggt aatagagcat aaagagaata
    10321 caaaatgcga ctaccgaaag attcagagca atcgaaggaa tgaaagatgt ttccaaggat
    10381 aaaatcagca agaagagact gataatcggt gtctgggttg ctactttgac catactatct
    10441 cacctcccct tgggtattgc tactctgaga tgtaagtggt ttggtaatgg tcacttcttt
    10501 cacatgccga agaccctgac tagtcatctc aatccaataa tcaaccacag aaatcaaagg
    10561 gtctaaacga tgactaatga gcagaaaact tcttccttga ttcctctcct ccacaatcca
    10621 cttgcaaaaa taatggcagg ctctatcatc caaacctgca aaaggttcat ctagcaagat
    10681 cacggaagcc ttactggtca agatggtcag gagctgaaga attttttgct gaccaccact
    10741 taattgatag ggactcttat cgactgcctg ctccaaatca aaatatcgta aagcttgaaa
    10801 aatccgctga tttctttcag aatcaggtcc atctaattga agctcctctc gcagactgac
    10861 tcggataaac tgcttctcag cttcctgaac aacacccgtc agatcacggt acaaactctt
    10921 tttctttttc aggactgtcc ccttccatgc aatgcgcccc ttatactttt gaaattgaag
    10981 aatagaccga aagagggttg atttcccgac accattgtca cccaggatac aggaaatccc
    11041 ttgatagaat gtgaaatcag caattgaaaa gagggggcga ttaccaagct caccagtcac
    11101 acggttcata tggaataatt ccgggctaga agcaacttcc tttgaagcaa cctgtgtcat
    11161 ctcataggaa gggatttgat ttatttccct tagttttccg tctcttagct caaccatatg
    11221 gtcgatatag gctttatagt cagataaatc atggtcgcac aaaataactg tcttcccatc
    11281 aagagccaac tcttttagaa tctccaatat ctcgattctg ctcttgcggt caatggaagc
    11341 gaagggctca tccaagagat ataccctagg attcatggca aagaggacag ccagcgctgc
    11401 tttttgcttt tccccacctg ataggtgatg aatgggacgg tgtaagattg cctcgcaacg
    11461 acattgctgg acaacctctg ctattttaga atcaatttcc tgaaggtgat agccgatatt
    11521 ctccaaggtg aaaatcaact cctcaaacaa gttctccatg gtaaattgat gattgggatt
    11581 ttgcaagaga atgccaacct tctggacacg tgcgatgata gaaagctgac tgacctcgct
    11641 cccatctatc aggacttgac cactataggg aagagaactg acttgggcaa tcatttgaaa
    11701 gaggctggat tttcctgaac cactgctccc aactaacaag gtaaaggctt gcgcatgaaa
    11761 agtaaaatca aacggctcag agaagattgg ggactgaatc gctcgtagtt ccagacccat
    11821 ctatgctttt cctccagttg caaactgatg atagagtttg acaatggcac gaaccaagat
    11881 ggtacagaag aaataaacag aaataaaacg taccacaagc aaggaaagga caaacggaag
    11941 ggaaaaggcg tagtaaccta acttaatgta ttcatagaca aagctaacaa gcgtaatccc
    12001 aatactatta gcagttagag agagccaact ttcatagcga ttcttagtta cgataaaacc
    12061 aaattcactt cccaaacctt gaaccaagcc agacaaaaga gctcctagac caaattggct
    12121 accataaagg acttcagcaa gcgcagctag cacttctcca atcgttgcac ttccgactct
    12181 cggaacaaag atggcagcaa tgggcgcagc catacaccag agaccgaaga ggatttcatt
    12241 ggcaaaggcc tgcaaaccaa gaggtgttaa gagtagactg agaatattat acacatatcc
    12301 tgaaccaacg aaaaccccac caaaaaagat agacaagaaa gcaagcaaga taacatcttt
    12361 taactgccat tttttcaaca taaaaaactc ctttttttaa agaaaagtgg ggcactcaag
    12421 aagaccgacc taaatacttt gtatagcaga ctgaatttag aacagtacac aagaacacta
    12481 aaatatttct agaaattaat ttgaattttc taattgattt gttcgcatct tatttcaatc
    12541 tactatatca tcttcatcca gtttcgtaaa agaaaaaact ctaattacag atacgaatta
    12601 gagttcagct tacaagatta gacagttctt ttcgacatac gaaaaaaaca tttcacattt
    12661 cccttcgcca gtcttaactg tatcaggttc aatgggtatc atctcagcct aaagcacccc
    12721 aaatgccttt attatttaat tatgtgatta ttataacaca cattttatac tagttcaaga
    12781 aattgaactg gaaatacagc cttgcactca caaagacagc agatctttct tttgcaaaaa
    12841 acaaatgacc tgtttgatga attagctatt caagctgaat ctagacatag ctttttaaaa
    12901 aaggaaaatc ctacttactt agaatccaag gatagatatc tattgttcac tcatttcccg
    12961 aacagttttt tctatatttt ttgcatacga tattgccgaa atgattgaaa cgccgtcaac
    13021 attggtcttt ataatgtctt taatatgttt cgtctgtatc ccaccaattg caactaaagg
    13081 catttgtggc aatagttttc tcatcaattc aagaccttca taacctatag caccaccagc
    13141 atcatccttt gactgggtat caaatacagg accaacacca acataatcta catattcaac
    13201 ttttgattgt tgaaattctt cctcgttttt tatagaaaga ccaattattt tatctggcat
    13261 caattttcta atttcatcaa caccaatatc atcttgacct acatgtacgc catcagcgtc
    13321 aatttccatt gctaaatcta tatcgtcatt aacgataaat ggaacattgt attttttaca
    13381 aagttcttta atttggatag ctagctcaag tttttctaag ccttctaaag caccctcacc
    13441 tttttctcga aattgaaata aggttatacc accttttaag gcttcctcaa cgactgtata
    13501 tagatttttt ccttggcaag tagtcgttcc acaaataaaa tatagtttta gtaattcttt
    13561 atgaaacatc ttacttcact cttttgaatt tcttgacatc ttcatctgta atttcatata
    13621 aggcatttat aaattcaact ttaaatgttc caggaagatg tccatttgga cgtttttccg
    13681 ccatttctcc agcgatattg taaaccaaca ttgctgtttc taatgatttc aattcttgac
    13741 ctttttcaag tccgataaag cttgctacta cagctcctaa taagcatcct gtcccaatga
    13801 ctttcggcat catagcacta ccattatgaa tcgttaccac ttctccatta acagcaatgg
    13861 catccacttc acctgttact actattggaa tattgaactt ctcatttgct gctagagcaa
    13921 tttcgtcaat attatctacg cccgcactat ctactccttt agatgccaca tctattccta
    13981 ctaaagaggc aatctctcca gcattccccc taatcgcagc tagtttgtaa ttgttgatta
    14041 aatcatctgc tacttttttt ctatattctc ctgctccaca ggctacagga tctaaaactg
    14101 ctgggacatt atatttctct gcaattttca gagcagcttg gtataatttc caattttcat
    14161 ctgtcaatgt tcctatgttt attaataaac caccagcata ctttaataag tcctctaaat
    14221 ctgctggaaa ctcactcatg gctggtgagg cgcccagtgc tactaatcca tttgctgtga
    14281 aattttttac tacatcattg gtgatgcaaa tgaccaaagg tgctttttct tttaataatt
    14341 ttaaacttgt catattgaaa tccttccttt tcactttata cgatctacta atttcgattt
    14401 atctttagtt gagaattttt ttcatttaca ttgaatgatt tatactcaat gaaaatcaaa
    14461 gagcaaacta ggaggctaac cgcaggttgc tcaaaacact gctttgagcc tgtagataag
    14521 actgacgaag tcagctcaaa acactgtttt gaggttgtgg atagaactga cgtggtttga
    14581 agagattttc gaagagtctt acctcatcaa atttgtaaat atcatgagcc ttctctagac
    14641 atcgtaacca atatcaaaaa aagctaattc taaagcgact gcttgattcc agcgttgctg
    14701 aagttctgtc aaatcttctc gatttttacc gacacgattg agttcatcaa ccagaaattg
    14761 aactcactct gcaaagaaag gacctctgtg gagattgatc cattccgaat gaatatagac
    14821 ttcaggtaga gccaaatctt tagaacccca gtctaaatag agaccttctg caatgaccag
    14881 cataaccaaa agatgggcat agtctgatga agccactgcc caatacatta gatcctgaaa
    14941 ggcttttgtt acagggtgca aagtcacttc tagatagtta ttctctgcta cttttaactc
    15001 tttaaaagcc ttttggaaat aaccatcttc atctgcttca agaaagccta gttgcttggc
    15061 aaaacgaagc ttggattcaa gtttatctgc gtgagctacg caggcaccca gcatggataa
    15121 gaaggcatca aagaagtgat aatcttgaat cagatagtcc tttaagacct tattctcaat
    15181 tgtccccgca aaaagttcct taacaaaacg atgattgatt gcagcctgcc aatccttctg
    15241 actgcttttt aataattctc caacagtcaa acctggctga aatgcatagt cttgtgtttc
    15301 catatttact tctcctctct ttacttgtta gtaattaata aaacagcaag aaatatcaag
    15361 caaaatcgta attccacttg atccttttaa agcacatcga gagcatttac agagagctaa
    15421 ctaaacaagc ctatccagtt tatataaaca aaaaactcca attacaatca agaattagag
    15481 ttgacttaca agattagacc gttcatttca ccatacgaaa aaactgttca catttccctt
    15541 cgccagtctt aactgtatca ggttcaatgg gtattatctc agcctaaagc accccaaatg
    15601 tctctattat ttaattactg aaccagtata gcaaaaaatg aaagccctag caagatattt
    15661 gaccgaaaaa tatctttata tacaatatat tgaaactaga atagtacacc tctacttcta
    15721 aaacattgtt agaaatcgat ttaactgtcc tgattgattt gtcctattct tatttcattt
    15781 tactatagtt ttcgatagcg atttattctt ccaatacacg aagaaaaacc tccacattca
    15841 gtgaaggcaa tctgttttat caatacaatt ttaagtcacg agggtcaact gggaaggttg
    15901 ggttgtatgg attgtgacgg agcttaaagt gtttgacatc ttcaatggtc tgagctccag
    15961 acaattgcat aactgtcttc aattccgcat tcaagtgttc aaagacttga cgcacaccga
    16021 cactaccacc gagagccaag ccataaataa cagggcgacc aatagctacc aagtctgctc
    16081 ctgaagccaa ggctttaaag acgtgttgac cacgacgaac accagagtca aagacaatcg
    16141 gcacacgtct atcaactgct tctgccactt cttgaagcga gtcaaaggca gctggtccac
    16201 cgtcgatttg acgaccaccg tggttggtta cccagatacc agaagctcct gcagcaagtg
    16261 aacgttcaac gtcctcacgg cattgtggtc ccttgacata cacaggaaga ccagagtatt
    16321 cagcgataaa ttctacatcg cgtggagaca agcgttgttt agctgatttg taaacaaagt
    16381 ccattgattt accagcacct tctggcaggt attcttcaac aatcggcatg ccaactggga
    16441 agacaaaacc attacgctta tccacttcac gattcccccc tacagtagca tctgccgtca
    16501 agacaatcgc tttataacct tcagccttca cacggtccat gatgtggcgg ttgataccgt
    16561 catccttact aaagtaaaat tggaaccaat ggggtgtccc ttgaagggct tcagaaatct
    16621 ctggaaggtc aacagtagag taagagctgg ttgtataaag agaaccaaac tcatgcacac
    16681 cacgcgcagt cgccacttcc ccctgttcat ttgccaattt atgagccgca acaggcgcca
    16741 taatgattgg tgaagatagt ttttcacctg caaattcaat ctctgtactt ggattttcaa
    16801 catcgcaaag tgtatgagga acgatgagtt tgtggttaaa ggcgcggata ttctctctta
    16861 aagtgaaagt atcttccgcc ccactagcga tatagccaaa tgctgcttta ggaataactt
    16921 gttgcgccat tggctccaaa tcataggtat tgatgaagtc tacatgacct tctgcattgc
    16981 ttgttttata tgacataaaa tgccctcctt gattaagtaa gcgtttgctt tttactacac
    17041 aactataata actctttttt caatcatttt caagagtttt gcttaaaaac catcttattt
    17101 tttcatacaa tatactagcc ctactttcct taaactctaa accttagtct atattaagtg
    17161 aatcgttgag attttttgct gccaggcatt tgaactactt ttttatttgc ggattctatc
    17221 tactaatact ataaaaaaaa caagtgaata agacaccaga acatcctcta ataggaccta
    17281 tggacttata tcagtcccat atatactgtt taagcaagat actatcctag ttgacgctaa
    17341 cttcctatcc cacttattaa ttttttattt atagtgaatc tgaacaaatc aattggggaa
    17401 tccaagtcaa tttctagtac tttttgaaca gtttcagcgt actatcgtaa aatgaaataa
    17461 aacatgcaca aattgattag ggaatttaaa ccaatttcta acaatgtctt agaaatcaaa
    17521 gtgtactatt tcaacttcaa tatactacac ttcattttct ccttaaattc agtctctttt
    17581 tgaatcaaaa aatcctctgg taagagccag agggtaagaa tttatttcat tgttgggaag
    17641 agcaatacat cacggatagt tgttgtatca gtgaggagca tgcagagacg gtcgataccg
    17701 attcccaaac cacctgttgg tggcataccg tattcaagag cctcgatgta gtcatagtcg
    17761 atgcctgtcg cttcatcatc accaagttct ttagctttag cttgggcttc aaaacggcta
    17821 agttggtcga ttgggtcgtt gagctcagta aaggcattac cgtactcctt agtcatgata
    17881 aagagctcga aacggtcagt aaagcgttgg tcttcaggat ttttcttagc gagtggagat
    17941 acagctactg gatgtccata gacaaaggtt ggttggatta aagtttcttc aacaaactct
    18001 tcaaagaagg cattgatgat gtgaccaacc tcagtgtagt gtttctcaac tggaactttc
    18061 ttctcagcag cgatagcttt agcttctttc aaagtcatgt cttgccagaa atcgacacca
    18121 gtaatttctc tgatagcatc caccatatga acacgcttaa atggttcgtt aatcttgatt
    18181 tcagtacctt ggtagttgac tgggccatcg cccttaactg atttagcagc atgttggata
    18241 atgccttccg tcaagtccat gatatcttgg aagtctgcat aagcttggta aacttcgata
    18301 gaagtgaact cagggttatg agtagcatcc attccttcgt tacggaagat acggccaatt
    18361 tcatagacac gttccatacc acccacgata aggcgtttta agtgaagctc agtcgcgata
    18421 cgaagcacca tgtcaatgtt ttgggcattg tggtgggtga taaatggacg ggcagcagca
    18481 ccaccggctt cattatgaag aacaggtgtt tccacttcaa ggaatccttt ttggtcaagg
    18541 taacgacgga tttcagagat gatttttgaa cgagtgacaa agcgttcaaa gctttcacga
    18601 ttagaaatca agtcaaggta acgtttacgg taaattgttt caacgtctgt caaaccatgg
    18661 aatttctcag gaagaggacg aagagcctta gacaagtgtg tgatgtgggt tgccttgata
    18721 gagagttctc ccatatccgt acgcatcact tcaccttcga caccaaggaa gtcaccaagg
    18781 tctgcttttt tgaagatttc gtagttttct tcaccgacag catccttacg aacgtagatc
    18841 tgaatctggc cttcgcggtc ttgaaggtgg gcaaaaccaa cttttccttt accacgtttg
    18901 gttaccaagc gtcctgcgat agtagctgtt tcgtttttat cgtgtaattg ttctttatcg
    18961 aggttggcat atttatcttt taattcttgt gaatttgcag tacgttcaaa acgttttccg
    19021 aaaggatcga ttccttgttc gcggagcgca gccatttttt cacggcgaac gatctgctgg
    19081 tcatttagtt cttccatatg ttctgtagac atgggatcct cctagtttta ctcaaaattg
    19141 aatacgatga gtcatttttt gcgatactcc cattttatca taaataagca agaaattcac
    19201 ggataatctt taaaaactaa aaagaacctg acgctaaaat cactggaaag aagtgaaagt
    19261 atcttccgcc ccactagcga tatagccaaa tgctgcttta ggaataactt gttgcgccat
    19321 tggctccaaa tcataggtat tgatgaaatc tacatgacct tctgcattgc ttgttttgta
    19381 tgacataaaa tgtcctcctt aataagtaag cgtttacttt gtatattata aaaatatatt
    19441 aactcttttt tcaaaacttt tcaaatattt tgtttggaaa tttcagaaat tttatgtcta
    19501 tgataaaaat ccttataacg gcaataaaaa atagatatta tccaaagaag attttaagtg
    19561 ctacaataac tgtattattt ctagatggga ggttctattt ttggattgat ccattgttga
    19621 acaatatcta ccactatatc aaaaggcatt ctttctgacc ttgcatattg cagtttgggg
    19681 aattttggga tcctttctgc tcggtttaat cgttagtatc atccgacatt atcgaatccc
    19741 tgttttagcg caagtagcga cagcctacat tgaattgtca cgtaatacgc cccttttgat
    19801 tcaactcttc tttctctact tcggtcttcc cctaatcggg attgtcctat cttcagaagt
    19861 ctgtgcaacg cttggacttg tctttttagg aggctcctat atggcagaat ctttccgaag
    19921 tgggctggaa gccatcagtc aaacccagca ggagattggc ctcgctattg gtctgacacc
    19981 tctacaggtc tttcgctatg tggttcttcc gcaagcaaca gcggtggtac tcccctcctt
    20041 tagtgccaat gtcattttcc ttatcaagaa aacctctgtt ttctcagcag tggctttggc
    20101 cgacctcatg tacgtcgcca aggatttgat tggtctctac tatgagacag acattgcgct
    20161 agctatgttg gtagttgctt atctgatcat gctgctaccc atctcactgg tctttagctg
    20221 gatagaaagg aggacctgcc atgcaggatt cgggaatcca agtactcttt caaggaaata
    20281 atctcctgag aatcttacag gggttgggcg ttacgattgg gatatccatc ctgtctgtcc
    20341 tcttatccat gatgttcgga acagtcatgg gaatcatcat gacctcccat tctagaatca
    20401 tacgattttt aacacgattg tatctggaat ttatccgtat catgccccag ctggtgctac
    20461 tcttcatcgt ttactttggc ttggctcgaa actttaatat caatatctca ggtgagactt
    20521 cagctattat catttttacc ctctggggaa cagctgaaat gggagacttg gtacgtggag
    20581 ctatcacttc tctccctaaa catcagtttg aaagtggata ggcactcggc ttgactaatg
    20641 ttcaacttta ctaccacatc atcatcccac aagtcttaag aagactgcta ccgcaggcta
    20701 tcaatcttgt cactcggatg attaaaacca cttcattagt tgttttgatt ggggttgtgg
    20761 aagtgaccaa agttggacaa caaatcatcg atagcaatcg cctgaccatc ccaactgctt
    20821 cattttggat ttatggaacc attctagtct tatatttcgc agtttgctac cctatttcca
    20881 aactatccac tcacttagaa aaacattgga gaaactaaat gtctgaaact atcttagaaa
    20941 tcaaggaact aaaaaaatcc ttcggagaca atcccatcct ccaaggactt tctctagaaa
    21001 tcaaaaaagg ggaagttgtt gtcatcctag ggccatttgg ttgtgggaaa agtaccctcc
    21061 ttcgttgcct caacggctta gaaagtattc aaggtggaga tattcttctg gatggtcagt
    21121 ctatcgttga aaataaaaaa gattttcacc tagttcgcca aaagattggc atggtctttc
    21181 aaagttatga actctttccc catctggatg tcttacaaaa cctcatccta ggccctatca
    21241 aagctcaagg aagggacaag aaagaagtaa cggaagaagc tttgcaatta ctagatcgtg
    21301 tcggtttact ggataaacaa catagctttg ctttgcccgt caattatctg gtggacagaa
    21361 gcaacgtgtt gcaattgtcc gtgccctcct aatgcatcca gaaatcatcc tttttgacga
    21421 ggtgactgct tcgctggatc cagaaatggt gcgtgaggtg ctggaactta tcaatgattt
    21481 ggcccaagaa ggccgtacca tgattttagt aacccacgaa atgcagtttg cccaagccat
    21541 tgctgaccgg attatcttcc tcgaccaagg gaaaatcgct gaagaaggaa cagctcaagc
    21601 cttctttacc aatccgcaaa ccaaacgagc ccaggaattt ttaaacgtct ttgactttag
    21661 ccaattcggc tcatatctat aaaggagatt cttatgaaac tattcaaacc actcttaact
    21721 gttttagcac ttgcctttgc ccttatcttt atcactgctt gtagctcagg tggaaacgct
    21781 ggttcatcct ctggaaaaac aactgccaaa gctcgcacta tcgatgaaat caaaaaaagc
    21841 ggtgaactgc gaatcgccgt gtttggagat aaaaaaccgt ttggctacgt tgacaatgat
    21901 ggttcttacc aaggctacga tattgaacta gggaaccaac tagctcaaga ccttggtgtc
    21961 aaggttaaat acatttcagt cgatgctgcc aaccgtgcgg aatacttgat ttcaaacaag
    22021 gtagatatta ctcttgctaa ctttacagta actgacgaac gtaagaaaca agttgatttt
    22081 gcccttccat atatgaaagt ttctctgggt gtcgtatcac ctaagactgg tctcattaca
    22141 gacgtcaaac aacttgaagg taaaacctta attgtcacaa aaggaacgac tgctgagact
    22201 tattttgaaa agaatcatcc agaaatcaaa ctccaaaaat acgaccaata cagtgactct
    22261 taccaagctc ttcttgacgg acgtggagat gccttttcaa ctgacaatac ggaagttcta
    22321 gcttgggcgc ttgaaaataa aggatttgaa gtaggaatta cttccctcgg tgatcccgat
    22381 accattgcgg cagcagttca aaaaggcaac caagaattgc tagacttcat caataaagat
    22441 attgaaaaat taggcaagga aaacttcttc cacaaggcct atgaaaaaac acttcaccta
    22501 acctacggtg acgctgctaa agcagatgac ctggttgttg aaggtggaaa agttgattag
    22561 tcattaactc ttaaaaggaa ctggatttta agatccaatc cctttttaag attttaccta
    22621 taacatcctg agtctatcta agatgttcaa tctgaacaca gtgtacatac tttatcttct
    22681 attgcatata ctttatcaca taagatacga atatcctctt cactatgact agcaatcaaa
    22741 attgttgtcc ctttttcact agagagcttt ctaaacaatg ttctcatatt ttctacactt
    22801 gatttatcca aggcattcat aggttcatct agtaaaagaa tagagggatt ctccataatt
    22861 gcttgagcaa tccctagctt tttcctcata cctagcgaat aagttttaac tttctggtct
    22921 ttttgctcat atagaccaac tattttcagt gtatcattga tttcctgatt accaactact
    22981 cctcgtatgc ttgccaaata ttgtaaattc ttaaagccac tataataatt tataaaacca
    23041 ggttcttcaa tcaaagctcc caaattagct ggaatttttc tctcaggaac aatattttcc
    23101 ccattgatta acacttctcc ataagacgga ctatataaac cagctattaa tttaaacaat
    23161 acacttttcc ctgagccatt cgcaccagta attcctataa tttccccctg tttacaacta
    23221 aagttaaggt tttgaaaaac acatgttttt tttaattcca actgaatatt ttttaatgta
    23281 attatttcat tcattctata aacctcctct tttgacgagt gaaatagaaa atgcttttaa
    23341 aaagaaagac taaaaatagc aactgaagaa ataaatctcg tcctatatct ccattccctc
    23401 gatttaaaat ataaaataga taattagttc gatttcctac aaatagacca ccaaacacaa
    23461 tcatgagtaa aaagaagcta acacaagaaa agttcatttg ctcattcgct cctagtacgt
    23521 ataacataaa gcaaaacaag actaacacac aagcattcaa agaatcaact ataaacaaaa
    23581 ctcctatatc ccagtttggt aactgtaaca taaattgaat cactagaact tttaccatga
    23641 ttaaaatgag tccataaaga aaacaggtcc aaatctgata cctaatccag agcttaatag
    23701 aagaaaatcg aatcacttcc ataaagaaat cggatgctct tctacgatat acaactgcta
    23761 gaaaaaatgt atgaataata aaccaatgaa gcaaccatat agataagact aaaaaagagt
    23821 tttgactcag attaggccct tttaaaattt ctataacaag tctatcattt ccttctaacc
    23881 aataccataa tcctaaacaa atcaatatcc aaaaaagaac ataaccccaa aagtacttgg
    23941 tatagattat ctgattcaac ctccacatgt gactacttaa ctttcccatt tccaactttt
    24001 acactctcct ccagtttcta tgaacagaaa atacagtcaa tggaattatg atagatagta
    24061 atgtaagcca ataaatcaat gcatacggat tggaatttac catatactga aaaattggca
    24121 ataatccaat tatcccattg tccaactgat aaatccagaa taaggattct acaaataaaa
    24181 aagtaaacag aaatactaag ctcatgtttg attttttaaa ccaagaaaaa ctgctaatag
    24241 taagtaagga taaaaagaaa tagtatgcta tataagagaa aaaaaatcct ataaaaaaac
    24301 tagcattgtt tgcaatactt ataccataaa attctcttaa aaaatcaacc tcctttatct
    24361 ccaaagagaa gctaaaacca ttactaaatg caatcagaaa aatcaataaa aataaagtcg
    24421 ccgtccaaat ccccgtacta agagctgcta atttgaaact aaaactggta aagtgcttaa
    24481 ttgatttcag acgaatacga cactccaacc tattaaaata gttattcatc aaataaaaaa
    24541 agaataatat atatgtgaac ggaaagcaat atactccagt cgtcatatct tgaagtaaaa
    24601 ctaagatcca ttctaataca tttggatgga ttgaatattg gcgacagcgc aataaatata
    24661 ctgtactaga taaaacacag gatagcagta atataaaata aaccaatact gctaagaaat
    24721 cttttttata aaattgaaca aattgtttca ttatacatag tcctctgaat gtagaaaaaa
    24781 tgtaccataa acaaccaaac aactaacaaa taaaataaaa gcaagatgcc cactaactaa
    24841 ggaaagactg atatctttct gatatcccaa agctagcgtt gtcacaggtt ctaagtaaga
    24901 tagccctaaa atagcccata aaataccacc aaccatcata taggcaactg ggatgaaaat
    24961 agctcctaat tttttcttca ctagcaaagc actagctagt ccaaaaatag agaacacagc
    25021 gccccaaact ccataccaga gagtcgtcac aagactatag agaaactgat tggaatcaaa
    25081 taattctttt aaggcaccac tataatctcc aatataaatt tcctgataag gagtcactaa
    25141 aagattaatt cctaataata ataaataggg gagaaaaaag actagaaaag aagaaataat
    25201 tgcagtacta cctacaatag ctagatacct ctttttagaa attcggcaca attgtgctgt
    25261 tagaaaatga ctctcagcat cctctattat ctgactagaa tagggcagtg tacagataag
    25321 tgcagctact aggctaatcg gtgaaaatcc tcgaatagaa gaagcggcaa aaaaaatcga
    25381 taaaccttca attttataaa taccattgaa agcaaggaaa tttcctaaac tcatgcaaag
    25441 aagggtcaaa aataaagaca tataaaaccg aggtgattga acgactcgta caagattaca
    25501 aatgaaaaat tccatcctta ctcctcctta taataaaaat agggtgtagc attctttttt
    25561 catgctacac ccacaatcaa ccatctttaa ggcttactct gacaagtaag ttaataagaa
    25621 tctggactcc aagaacctga agtatgaatt cttacataat ttccaaattg tggcgccata
    25681 gctaatctag taccagaacc aatataattg tcaccacctc cattatagta catgacaatc
    25741 ctagagccag accccaatga atataccggg gtaatatctg acccactata ggcgctacga
    25801 atagaggtat ttaacctttt accgccacca gtgctgtcac tattattaat tccagcagag
    25861 gcgttttctt tctcaagctc actagttgta tccgaacccc aacgcggcaa cgttaaatca
    25921 taatttccaa tctgtctagc taaaactgta gggagaaaca aactagatgc aattgtaact
    25981 acgcaaaaaa ggaatatatt tttcttcttt tcatgacatc gtcctcttaa gaagtgataa
    26041 acaagatagt tgattgatca atttgataca tattacattt tcattatatc aataaaagaa
    26101 agcgttgtca attattttat ttaaaatatt gtcatatttt aaataaaatg gtaaaagaga
    26161 ctcggtagcc tcgtctctct ttatcttact gacctaacct tcttgccaat tttcttggtc
    26221 ttctttaaag cgttttagaa gatcaaggcc ctctggcgtg atgtaacctt cttcttgggc
    26281 tagatggata agctcgctat agtttgaaag cgtcacaagt ttaacaccag catctgcaaa
    26341 gttcttatct gcttttggca attggtagct gaaaatcgct acaactccaa gtacatctgc
    26401 tccttctcgc ttggctgctg ctacagcttc aagaactgaa ccacccgttg aaataaggtc
    26461 ttcaaccact accatttttt gaccttgagc tacgcgacct tcgatttgat taccagctcc
    26521 gtggtctttt ggtttgctac ggatgtaggc aaaaggcaag tccatcttat cagcaataat
    26581 ggctccgtgt ggaatccctg ctgttgcagt tcctgcaatc acttctactt caggaaaggc
    26641 ttctttgata gcttccacaa aaccattttc aattagggta cgagtttctg gataggctag
    26701 tgtcacacga ttatcagtgt aaatcggtga cttgatacca gatgcccaag tgaagggttc
    26761 ctctggtttg aggtaaacgg cttggatttt caagaggtgg ctagcgatat ctttagcaag
    26821 tgtcatggta ttctcctttt atttttctaa tctagttctt taattccagt cctgtgtcca
    26881 ttcatccttg atggcatgat aagctgcaac aggatcctca gcttgggtaa tgggacgtcc
    26941 cactacgata tagtcactgc cgatttgata ggcatcagca ggtgtcatga ctcgtttttg
    27001 atctccaact gcaacaccag ctggacgaat ccctggtgtc agacagataa aatctggatt
    27061 ggtagcctgc ttgatgactt gtacttcctg agccgagcaa acaacaccat ccaagccagc
    27121 ttcagctgtc ttcttggcat agtgaatcac agactcttgc agactggttt ggatattttg
    27181 aaactcctgc atctgagctt ctgacgttga tgtgagctgc gttacagcga tcaatttggc
    27241 ttgactccca agaccttcac gcgccgcctt catcatctct acaccaccag ccgcatggac
    27301 attagtcata tcgacaccaa gctgagacaa gaccttcatg gctgacttga ctgtattagg
    27361 aatgtcatga agtttgagat ccaaaaagac actatgaccc aaacctttta agtaggacac
    27421 aatctcaggc cccgctgcgt aataaagctc catccctacc ttgagataaa ggctttcttc
    27481 tgctgggaaa agagctaaaa attccttgac cgcctcaaaa ctaggaaaat caagagcaat
    27541 gattggacga tgttctcgca taggtttctc cttttacctt tactagtgag agagtctggc
    27601 caacagaagc cacgaaaaaa ggaacctgcc aacagcaagg ttccacgaaa aatgggtagt
    27661 ctccaccctt tcaccgtcta accttagctg cctctctgga ctgctttaaa ggttttctat
    27721 tattctatta tttctactag cacttgtcaa gtaaaaacat ggtcactaaa gaactataag
    27781 agaaaaggta aacctagcga cgcgatgagc gctgggtcgt ttgatttcga ttgctctctt
    27841 cctcttgttt tttctgttct tcttcctgtt ttttctcggc ttccttggcc tcttgtttgg
    27901 ctttttcctc agcctccata attaatttat ccgccacagt gtaactgtaa attccagctt
    27961 ccatgtcgac cacactcggt tctgacaatt gtggcttaat cttactgtaa tatggcagtt
    28021 tcttactcat ttcagataga ggaaccaaga cttcgtccga atcattcatg gtcaatcgaa
    28081 ttaaatcgga tgtcaccttg cttggggcta attccacctt ttggatagcc gccttgagtt
    28141 ctgggctaat ttgagcaagt tctgagacaa aaaccttgat ttgttcacta tcattaaaga
    28201 gaactgataa ataagtttct ggtaaactgt tcagactcac agaactagtc tcaagctgac
    28261 cactggaaag aataggataa tgattttcac cagaaatata gtaggccaca atatcatatt
    28321 ccttgacctt aatagtgaac ttagttggaa attgatagac aagttgagct gattcaaccc
    28381 aatagttaga cttaatctgc ttttcatatt ttgccttgtc tagcagaagg ttaatcgtat
    28441 aatccgaatc ctgaatgcct gaagcctgtc gaatatcatc agctgtagtt tgcaccgttc
    28501 cctcaacacg aatatctttc atggtcgcat aaggactgag caagtaggca gagacaatca
    28561 ataaaagcag acttggaaat aaaatcgtga aggctcgcaa gatatggata ccaggaatct
    28621 ttgctttggc tggtttttcc tttgtagcct ttttagaaag ctttttatcc tgttcctcct
    28681 tctctttaga ctctggttct tctttctctt ctttctcttt gtcagcctct gaggatgcta
    28741 ctttttcttc agactcttcc ttagctgatt ctgaatcttc ctggtctgtt tcactctcct
    28801 ggtcctgttt gtcctctgac ttctcagatt cttctcccat tcgagcttgt ctttcctttt
    28861 ccttctcctc agctagagcc gcctcttctt cagccttctt ttttagatat tcttggtttc
    28921 gtttctgcca ttctgataac tctttcaatt cttcgaggat ttctttgtcc tcatttttct
    28981 tatcttttga catttacttt ccttatgata aatctttttt caacaattga taaaaatctg
    29041 ctagagattt caattcctta gaagccttca tcttagcttg gtaatcttcc ttgtgactta
    29101 gtaagtgaga aagcttctct tccaaactat ccaaggtcaa atcgctttct tgaaggtctt
    29161 ctgcatagcc tttttttaca aagtaagctg cattttcaag ctggtcacca cgactagctt
    29221 cacgaccaag cggcacaatg acatgcaatt ttgctatcgc caagagctca aaaatcgtat
    29281 tggcaccacc tcgtgtcaca acaatatcag ccaattccat caagggttga tagagatcgg
    29341 tcacatagtc aacacgaaaa agattttggc tcaactcatt caggctagaa tctccagtta
    29401 gattgataat attgtagcgc tctgttagtt ctttcttatg gtctgtcacc aattggttaa
    29461 agacacgagc acctgcagaa ccgccaacaa acaatacagt cggcaattta tgattaaagt
    29521 ggctttgaat atccaccaat tcatctggtt ctggattttt ttgatctgaa accttggtca
    29581 ctgctcccac atgctcaacc ttagacaaac tcgaagcttg ctcaaaggtt gaatacatct
    29641 tagtcgcaaa tttataggcg attttattgg ccaagcccat agacaggtca gattcgtgaa
    29701 taaagacagg cactcctgac acacgcgcag cgataacagg cggtactgag acaaagcccc
    29761 cctttgaaaa aagggtctgt ggacgaagtc gcaacatgat aaagagcgat tggacgattc
    29821 cccagcaaac tttgaagacg tccagcatat tttgccaaga gaaatagcga cgcaattttc
    29881 cagtcgcaat agaatggaag gtgacatcca aacctgactt aaggatttct tggtgttcga
    29941 taccacgctt gtccccgata tagtggactt cccaaccatc ttcgatgaac ttgggcatta
    30001 acaaaagatt gagggtaacg tgtccaaccg tccccccacc tgtaaagaca atttttttca
    30061 tattattctt ttaactccgc tactgtgtcg ataaagaggt cgccacgtac ttcaaagtta
    30121 gcatacatat cccagctggc attggcagga ctaagaagaa ccacatctcc ttgagtcgca
    30181 agctcatagg ccttgcgggt cgcatctgca atatctgtcg cctccacata agcgacacca
    30241 gccttgtctg ctgcccgttt gacacgttct gcagattgac ccaggatgac catcttcttg
    30301 agtccagtaa tgtctggcac caattcgtca aactcattgc cacggtccaa accacctgca
    30361 atcaagacga ccttgctgtt atcaaatcct gacaaggctt tttgagtagc caagatatta
    30421 gttgatttac tgtcgttata gaatttaaca cccttgatgt catccacaaa ctggagacgg
    30481 tgtttgacac caccgaaggc tgaaagagtt tccttgatgg tttgattgtc cacaccacga
    30541 agcttggcta cagcaatagt cgcaagggca ttttccacat tgtggctacc tggaacaccg
    30601 atttcattcg ctgccatgac tacttcacca cggaagtaga gttgaccatc ttccagataa
    30661 gctccatcaa ccttttcaag tgttgaaaat ggtacaacag tggcttctgt cttggaagtc
    30721 aagtcttttg ccaagtcttg attaaagttc aagacaagga aatcagctgc tgtcatcttg
    30781 ttctggatat tccacttggc tgctacatat tccgaaaatg acccatggta gtcgatatga
    30841 gttggcatga ggttggtaat aaccgcaatc tctggatgga attcttgaac acccatgagt
    30901 tggaaagaag aaagttccat aacaagcgtg tccttatctg atgctatttg agcaacctga
    30961 ctagctggat agccgatatt ccctgataaa agaccatgtt gcccagcagc agtcaaaact
    31021 tccccaatca tagtcgttgt ggttgtctta ccgttcgatc ctgtgatacc aataatcggt
    31081 gcttctgaaa tcaaataagc caattccacc tcagtcaaga ctggaattcc cttggccaaa
    31141 gccttttcaa tcatgggatt gttgtagggg atacctggat ttttcaccat aagggcaaac
    31201 tcttcatcca agagttccaa aggatggcca cctgtaatga ccttgatccc ttcttccagc
    31261 aaactttggg cagctggatt gtcctcgaaa ggtttcccat catttactgt cacaatggca
    31321 cctagcttgt ccaacaaacg agctgcagat tcaccagact tggccaaacc taaaacaagg
    31381 actttcttat ttttaaattg atctattact ttcatgtctc gaactccatt tctactccta
    31441 ctattttacc atttttatgg aaataaaaaa gccacaaagt gtgtttgtga ctctttcttc
    31501 taactgaatc ttaccatatc atctatgtga taaatcggta actcgaatga cctgatccac
    31561 ttgttcccaa atcagaggat tgtgggtcgc aataataatg gtccgattcg gattttttaa
    31621 agattctagg atggaaagta attcctcaga gtttttgggg tctaaggaag tggttggttc
    31681 atctgcgagg atcaaaggtg gatcctttaa aattatcttc gctaatgcaa cacgttgtgc
    31741 ttctcctcct gataactcaa atataggttg cttcaaatcc aaataagaga ggtttacaca
    31801 gtttagagct tgtttcatca aagagatttt ctctttttcc ttcaactttt taccaactaa
    31861 acccagattg agattctctt tgacggtttg gctttcaatt aagccaaaat cttgaaataa
    31921 gtatcccaag taatctctaa agaaaacaga aggcttgatg tccttaagag aagtaccatc
    31981 atagatgatt tgtcctttgt catatggctc taatcgtcca atcatattca agaatgttgt
    32041 cttaccacag ccacttgtac cgattaaggc ataaattttc ccaccttcaa aatgaagatt
    32101 tgtatctgaa aatagctgac ggcttccaaa ttttttagat atattcttta gttcaatcat
    32161 cctattttcc tttcataatt gtcatagaaa cacgagattc tttctgcgct tgacggtaaa
    32221 gcgtcagaac tgcactagct agaaagacta ataaagtgag caagccaatc accaagtctc
    32281 gactgcttaa aataaagaga ctagcaccaa atacaaaact ggcaaattga ctaaccatat
    32341 actgagcatg tgtttcaaaa aatcgtaaac ctgaaattcg tttaatcaaa atatctcggc
    32401 ggaattgctc gaaatataga agattgacag aataaaatag taacaaggaa ctagctatcc
    32461 ccacaatagc tcctaagatt aaagttgctg tttcagtttg aacttcatta taacgagtta
    32521 gataaacact tcttccttct ttaagatagg atacttgctc ataaattcca gctttcttca
    32581 agagttctag cccactctca tatcctttga taaagagttg ttttccagca ttgatagacc
    32641 aactagataa ggatataaaa ctatcacctg tagaagtcgg cgtgaatacc actaaaatcg
    32701 gatcagtcaa atactgagta gatacgggat tctcaccgtt attataaaca aaccgctttt
    32761 ctcccattga aagataacta acgtgcgctt tcatctcata atccaaagga gcacttgcct
    32821 cctcaccaga ttttccataa taactcaatc tttcttcaaa aactttctta agttctgctt
    32881 ctcgagagcg caaatgttct gggagcaaga ggataaactc acctttttgg agatgggcta
    32941 acttctgttt ggtctcagca tctaccacga ccttttcctt gtccaaataa ctgggactaa
    33001 catagagcgt attagcatct ggactatagg tatccagtgt ctctccctgt tcattttttc
    33061 cttgtggatt ggcaaaatgg agcagattat cctttacata aagagcttgt tcttcttcga
    33121 ttgcttcctt ggcaaaggca taccacttgc tctgattttc tgtatctttt cctctatcac
    33181 ctaagccaaa agaaatttga taatagtctg ctctatcctg ccatgcttgt tttgaaattt
    33241 caagttcttt caatcgttgg taagacatca aacctgtctt aacagcgtag cctactgtaa
    33301 agacagcaac caactgacac aatagggtta aaatcatcag gcgtttaagg ggtaatctcc
    33361 ccttaataac gggaactaat gctttgtaac tcaaactcat tagataaaga agcattagta
    33421 aaattgaaat cgccaataaa aacaacagat agaaactaat cccaaaacca taggtggcta
    33481 acaagatagg ataaaacaaa ccttgactaa aaagaacgac tcccccacct aggaaggaaa
    33541 ggagggctga tagaaggagc catttgatat cagtagataa agaatgcccc atgatggata
    33601 agagagtctg accagaaaag agttttatac ctgctgctct catttcctta atccgagtga
    33661 taatcactaa agcaaagaaa gataagccaa atattgctaa actaattaaa ataaggggat
    33721 ttagtaatat tcgaaaagca agaaaatagg gcggtatctt tcggtcagca cttgctttat
    33781 aacccaaatc tcctaattta tcggcaagct tttctttcgt caaggagcct gacaaaagga
    33841 gataactatt tagcggatca ctacgttcac gactttcttg gctagcttct tggaattctt
    33901 ttggtaaagt tccctgacca taagttgcat aagtaaagtg agtcgtccca tccttactcg
    33961 gctctacaat tcttctagct attaaactct gttctgagtt tgcaaaattc tccaattcct
    34021 gttcaaatac ctcacgcgtc ggttcctgag tatctttttt gacacgaagt aaagaaacgg
    34081 aatcatagct tgcatataaa tattgtggcg cacgtaagac aataatccaa gcaaggaaga
    34141 agctgagaaa aaagttgata ataatatgaa tagtttcttc atagtagact ccttgtaaac
    34201 aaaattcccc ctgtaatttc ttacaagggg aacgatttaa atcaatgaac gattagtcat
    34261 aatcacagta aaatgctact tgttctcccc atttagtcca aatccatgca taggaggttt
    34321 ttccagcaga agcttctcct ttatctgaat gactattcca tctacttaca agagaagaat
    34381 aatgatattt tttaccatga tagtaatttg aaaaagccca accacctcct gaaccttctc
    34441 catacgtcca tactcctcca tctggatatt gtacagcagc tgatgcagct cccaataatg
    34501 taaaacttga aataagagct agagcaagta atctatgttt tttcgttttc attttatttt
    34561 ttctttcaaa aaaagcacac cttgagcaac aatgcaacaa aataaaccct cctctctctt
    34621 ttgttgaaac cgctttctta tgtgataaaa atatcatttt tattatttgt tgtcaaggaa
    34681 aaaatcgaat tttttagata ttttactaca ttgcctctat gaataatatt atatagtagt
    34741 tttattttaa aataatatgc aaccagtact aaccaaatat aaaatagatg ccattaacga
    34801 attttattca agtttttccc attcatacta tccaagcaaa agagatgatg ttatagtaca
    34861 aaacaattca aactattgta aaattcctag caaaaaagag agccaaaact ctctttttta
    34921 tcttctttta ctttttttga ctggcatgag tgtaatgtct ctaacactaa agtaagctag
    34981 gatcaacatg gctattgcta ggaatatttc tgttggtaat tgaaaaattt tcagaaaaga
    35041 tagaaccaat aaaatcaaga gtgccactaa aatacatacc atagcgacga tattgactgt
    35101 ccctttaatg ctttctggtg tcgcaaatac atagagtagg agcagtaaaa ttcctaggac
    35161 taaatagacc atctttctct ctttctagct cttattcagc tgattttttc ttcttgttag
    35221 ctttctcacg ctctgctttg ttaaggattt gtttacgcaa acggatagac tcaggcgtta
    35281 cttccatgta ctcatcgtcg ttcaagaact caagagactc ttcaagtgtc aagatacgag
    35341 gcgtcttgat aacagctgtt tggtccttag tagctgaacg aacgttggtc atttgttttg
    35401 ccttcgtgat gttaactgtc aagtcatttt cacgagagtt ttcaccgatg atcattcctt
    35461 cataaacctc agtacctggg ttgacaaaga tcgtaccacg ttcttcgata gacatgattg
    35521 agtaagttgt agccttacca gcatcgatag aaacaagggc accacggtga cgtccaccaa
    35581 tttcccctgg aatcaatggc aagtattggt cgaaggtatg gttcatgata ccgtaaccac
    35641 gagtcattga caagaactca gttgagtatc caatcaaacc acgcgctgga acaaggaaga
    35701 ccaaacgagt ttgaccatta ccagttgaaa tcatatccaa catttcacct ttacgttcag
    35761 aaaggctttg gataacagac ccttggtatt cttctggagt gtcgatttgt acacgttcaa
    35821 atggttcaca tttaacaccg tcgatttctt ttacgataac ttctggacga gatacttgaa
    35881 gttcatagcc ctcacgacgc attgtttcga taaggattga caagtgcaat tctccacgtc
    35941 ctgaaacagt ccatttatct ggtgaatcag ttgggtcaac acgaagggaa acgtctgttt
    36001 gcaattctgc ctgcaagcgt tcttccacct tacgagaagt tacccattta ccttctttac
    36061 cagcaaatgg tgagttgttg accaagaaag tcatttgaag agttggctca tcgatgtgta
    36121 ggattggaag agcttctact gcatctgtcg gagtgatggt ttcaccgaca aagatgtctt
    36181 ccatacctga aacggcaatc aagtcacccg ctttggcttc ttggatttca cgacgttcca
    36241 aaccaaagaa accgaagagt tttgtaacac ggaagttttt agttgtaccg tcaagtttag
    36301 aaagggtaac ttggtcccca accttaactg taccacggaa gacacgaccg ataccgatac
    36361 gtccaacgaa gtcattgtag tccaaaagtg acacttggaa ctgcaaaggc tcatctgagt
    36421 tatctactgg agctgggata tggtcgataa tcgtgtcaaa gattggtgcc atagtcgctt
    36481 cttggtcagc tggatcatct gacaatgaag aagttccgtt gatcgctgaa gcataaacca
    36541 ctgggaaatc aagctggtcg tcatctgcac caagctcgat gaaaagttcc aagacttcat
    36601 ccactacttc tgctggacga gctgatggct tatcgatttt gttaacaacc acgattggga
    36661 caaggtcttg ttccaaggct tttttcaata cgaaacgagt ttgtggcatg gttccttcat
    36721 aggcatctac gaccaagaca acaccgtcaa ccattttcat gatacgctca acttctccac
    36781 caaagtccgc gtgtcctggt gtgtccataa tgttgatacg agttccgttg taagcaacgg
    36841 cagtgttttt agcaaggatg gtaatcccac gctctttttc gatatcgttt gagtccatag
    36901 cacgctctgc caattcagta cgtgcatcaa gcgtttctga ttgtttcaat aattcgtcaa
    36961 ccagggttgt tttaccgtgg tcaacgtggg cgataatcgc aatgttacgg atatcttctc
    37021 ttaattttgt catgatttcc tctataatat tcaaaattta ttttctaact gaacgattat
    37081 accataattt caaataaata acataactca agcaagtgta aatgttttca ctccgctttt
    37141 cttttcacgt caagcctttt caaagcaagc gacttatgat aagataggca cagtatgcgt
    37201 ttagataatt tattagccca agaaaaagtt agccgaaagg ccatgaagca agcactcctc
    37261 agaggggaaa ttctagtcga tggttgccca gcccgctccc tagctcaaaa tatcgataca
    37321 ggactacaag aactcctttt tcaggatcga atcattcaag gctatgaaca cacctatctt
    37381 atgcttcata aacctgctgg tgtcgttaca gccaacaaag acaaggaact tccgaccgtc
    37441 atggacttgc ttccatctga catccagtct gacaagctct atgccgtcgg ccgactggac
    37501 cgagatacaa caggactcct tctcttgacc gataacggtc ccttgggctt ccaactcctc
    37561 catccccaat atcatgtcga taagacttat caagttgagg ttaatggact tctaacacct
    37621 gaccatatcc aaacctttca aaaaggaatt gtctttttag atggcactat ctgtaaacct
    37681 gcaagactag agattctatc agcaagtcct tccctcagtc aagcctctat caccatttca
    37741 gaaggaaaat ttcatcaaat caagaaaatg ttcctctcgg ttggtgttaa ggtgactaac
    37801 ctcaagagaa tccaatttgg ggacttcaca ttgaacccag atttagcaga aggtaactac
    37861 caccctttga accaaaaaga gttacaaatc attaaaaact atttagagat gagtcgataa
    37921 aacaaaaaaa gctttaaaac taaagctttt ttcttttatt taccgaaaaa ttaaggcgat
    37981 tgctacaatc cagttaacta cagaaatcac aattcctaag atattaagaa tcttttctat
    38041 tttatagtct aattgtgact ctttttggta tgaaatagcc aagaccaatc ctatgatacc
    38101 caaaatcagg cctacaattg gaaataacaa accaagaata atcgacaaga tacccacaaa
    38161 aagtggattt ttcttctttt ctttcatgtt ctaagaactc tttaaatttt atacaaatta
    38221 attatactat aaaacaatag cttcattcta tcattcgact aatttggaaa taaggttagc
    38281 tagtcttcac tttccctttc caagaatcca agccataaga aaggatataa atctcagaaa
    38341 aaccttgttt tttcaagtaa agagctgcat ttgtaactcg ttgcgcacgt tggttttcgt
    38401 agagaaggac aggtttatct ttacgaaggg ctgcaagact agttttcaac tgacttgaag
    38461 gaatattgcg tgcaccaagg atatgttttc tgtggaattc tgctgggtcg cgcaaatcaa
    38521 tcaattgacc cgtacgaatc aaggcttcaa actcctcatt gtccacaatt ttagccgcac
    38581 ggcgaatacg aagatagtta aagcccatcc acgccaacat tgctagtata agtgcccaca
    38641 aaatccaagt aaccattagt tcttttctcc atttttctca atataatcca attctacctt
    38701 gtgctctctg cgaagaactg cttctgcctc tagatagtct aatttatcca tcaaccctgc
    38761 atcgtaaatc cgagatagtt ccaacttcat cagttcaata tcatataagc gttttcccat
    38821 gtaaacaata ataccaaatc gtttgaggaa ttgctgcaca tcatagaatg ttttcataag
    38881 actcattcta gcaaaatttt gtgttttttt caagaagaga ctcacacaat gctccttatt
    38941 ttcctatctt ctttagcgat tctaaggcaa gtatggtaca ataaaaacat gagaattcaa
    39001 caattacatt atattatcaa aatcgtcgaa actggctcca tgaatgaggc agccaagcaa
    39061 ctctttatca ctcagccaag tctctccaat gcagtgcgag atttggaaaa tgaaatgggc
    39121 attgagatct ttatccgcaa tcccaaggga atcaccttga cccgtgatgg gatggagttt
    39181 ctctcttatg cccgtcaggt tgtcgagcag acccagcttc tggaggaacg ctataaaaat
    39241 cctgtcgccc accgcgaact ctttagcgtt tcgtctcaac actatgcctt tgtggtcaat
    39301 gcctttgtct ctttgctcaa gaaaagcgat atggagaaat acgaactctt ccttcgtgaa
    39361 actcggactt gggagattat cgacgacgtc aagaacttcc gcagtgaggt cggggtcctc
    39421 ttcttaaaca gttacaaccg tgatgtttta accaagatgc tggatgacaa tcacctgcta
    39481 gcccaccatc tcttcacagc gcaaccgcat atctttgtca gcaagaccaa ccctctggca
    39541 aagaaagaca aggtgaaact gtctgatttg gagaatttcc cttacctcag ctatgaccaa
    39601 gggacgcaca actccttcta cttttcagaa gagattcttt ctcaggaaca ccacaagaaa
    39661 tccattgtgg tcagtgaccg tgccaccctc tttaatctct tgattggttt ggatggttat
    39721 accattgcga cagggatttt gaacagcaac ctaaacggag acaatatcgt ttctatccca
    39781 ctggatattg atgacccgat tgagctggtc tatatccagc atgagaaaac cagcctatct
    39841 aagatgggcg aacgctttat cgactatcta ctagaagaag ttcagtttga tagttgagaa
    39901 atgataagaa ccaatatgta ggctagcaac aacctgcaca ttggttcttt ttacttataa
    39961 ttaaaagttt cccctgccaa cttatcagct agcttgggaa agagagtata aaacttatgg
    40021 gctaggttca acaaaatcgg gagattgagt tctcgtttat ttttgcctat aatcttgaca
    40081 atctttttag ccactgcatc tgcctctaag aggaagcggt caaccgattt aagataagtt
    40141 ccatctgggt cagcttggtc aaaaaatcct gttcggattg gacctggatt gactgttgtc
    40201 acatagactc catagggcat aagttcgagt cgcagagcat ttgaaaaacc aatagccgca
    40261 aacttggtcg ctgagtaaag actagacttg ccagtagcta ttagacctgc catgctgacg
    40321 atgttgatga tatgcccttt gctgctttcc ttcatacgag ccgcaaggtg acgagacaga
    40381 ttcatcaggg caaaggtatt gacctcaaac atctggtgaa tatctttatc agcaatctgg
    40441 tcaaatccct caaaaatccc gtaaccagcg ttgttaatca agacatcaat cttgccatag
    40501 cggagataaa gatcagttac cagagcttct agggctgaat cgtcggtaat atcaatttca
    40561 atcaattccg catgggaata atttccgtag agttgggcta atttttcctt atttctacca
    40621 agcaagatga gttggtcatt gggcaggagt ttgaccattt cttgagctag accaccgcta
    40681 gctccggtaa tgagaatagt aggcatactt atcctttctg tgactgctag atttccactt
    40741 cttccaagtc tttgaccaca tggacatttt caaaaattgt ggcagcgtcc ttcttgagtt
    40801 tgcttatatc ttttgagagg aaacgggcac tgatatggtt gagtaggagg cgtttggcac
    40861 ctgcttctac cgctacttgt gcagcttgca tattagttga gtgaccatgg ttacgagcaa
    40921 ttttttcatc acccttgcca taagtggact catgaactag gacatctgca ttgacagcca
    40981 gacgcacact ggcatccgtt tttcgagtgt ctcctaaaat agtgataatc ttacctggac
    41041 gtggcgctga gatatagtct gctgccttga tttcagttcc gtcttccaaa acaagatcct
    41101 ggccgttttt gattttacca aaaagcgggc cgaacggaac accagcagcc ttgagttttt
    41161 cagcatccag cgtcccttct agatcctttt gcatgacacg atagccaaca cagaaaatag
    41221 tgtggtccag ctcctctgca tacacagtga atttatcggt ttcaagaatt ttacccagag
    41281 aatcttggtc aaactcatgg aaatgaatgc ggtagggcag acgagaacct gacacacgaa
    41341 ggctggttaa gacaaatgac ttgattcctt gaggtccgta gatttccaaa tctgtctgct
    41401 cttcattggc ctgaaaggca cggctagaaa ggaaacctgg caaaccaaaa atgtggtctc
    41461 catgcagatg ggtaataaag attttgctga ccttacgtgg tcgaattgtg gtttccagaa
    41521 tgcgattttg cgtaccttct ccacagtcaa agagccaaac ttcgttaatc tcgtccaaaa
    41581 gtttcagggc gagacttgaa acgttgcggg ctttagaggg ctgaccagcc cccgttccta
    41641 aaaattgaat atccattcga tactttctaa ttaatcaata tataacatgg ctgtgcggtt
    41701 ttccgatcgg aaatagcgtt tgccagaaaa agcagcagct tcttgcaata aatcctcttg
    41761 gctgtagcct ttgagacgtt ttcgaccatc agccaatctt tccaaatcag tcaaagctgt
    41821 gagactttct aggctgacaa cttcctcgtc cttgacaggt ttcatgtaaa tcttaccaga
    41881 ctcttcaaag actaattgat gggagaaaat ttgcgcaatt tcaaagagca agtcatccga
    41941 gattttctcc tcattttcag agaaaatccg accaaggccg tcactctcat aacaaaaacc
    42001 aaaggattta ccagacagat taagccgaat aaaaggctta ttttctaggg tgaaacttgg
    42061 ctcagtattg taaagattca gttcctgact gagttctgca aaataatccg tcgcagcctg
    42121 aggacttttt ttctgataga gttctgcaaa gtaggcatta acaacacttg gcggaggtgt
    42181 aataagtgtt aactgctcct gctctgtttt accagctaga agctgatcca gatagacctt
    42241 gtccagactt gtataacctc catactttag agccaaagtt ttaatatcag tcataaaatt
    42301 cttctaacct ccatttattt ttctcggaaa tgtagcctgt aatcacttcg ccgtcttcct
    42361 gataatcacg ttcttccaga attgcaacac tctctaaatc atgaatcttg taggactttg
    42421 aaaaaggcac tcgcagggta aatgcttcaa aaatttcctt aatcttatct agcaataatg
    42481 cttgcaagtt ttcacgactg tcctcagact tggcagaaat gagggtatat ggcgtttggg
    42541 taggcgtgaa atcctccacc aaatccgctt tattataaag cgtcaagtga ggaatatctt
    42601 ccatgtccag gtctttcatg atggagagaa ccgttttttc atgctcctcg tggtaaggat
    42661 tgctagcatc gataacatga accagaaggt ccacatgctt gctttcttcc aaggttgact
    42721 tgaaactgga caccaactct gtcggcaaat cttggataaa gccaacggta tctgtcaaag
    42781 ttacttggag attgcctccc agatgaatac tcttggttgt cgcatccaga gtcgcaaaga
    42841 gctcatctgc ttcatactgg gtcttactgg tcaagatgtt catgatagtt gatttcccag
    42901 cattagtata accaatcaaa ccaatcttaa aagtgctaga ctccaaacgt ttttctctga
    42961 cagtcgcacg atttttctca accaccttga gctggcgctc gatatccgtg atttgattgc
    43021 gaacgctacg acggttcagc tccagttggc tttcaccagg accacgggaa ccaattcccc
    43081 ctgcctgacg gctgagcata atcccctgac caaccaagcg aggcaagagg tatttgagtt
    43141 gggctaggtg gacttggagc ttcccttcat ggcttcgagc ccgcatggca aagatatcca
    43201 aaatcaactg catacggtca atgaccttaa caccgagaac ttcctctaga ttgacattct
    43261 gccttggggt cagacggttg ttgacgatga cagtagtgat ttcttctgca tccaccataa
    43321 gcgcaatctc ttccaactta ccagagccga cgaaggtctt ggaatcatat ttttcacgtt
    43381 tttgtctgta gctatctaca acgactgccc ctgccgtttt cgctaaacta gccaattctt
    43441 ccatggagag gtcaaaactg tccataccct gcaattccac accaatcagc aggactcgct
    43501 cctctttttt ctccgtttca atcatctaaa aactcctcta tctggcttaa aatgcggtct
    43561 tgtacaccag attctccaat ctgataaaag gtgacctgca tgcgattacg gaaccaggtc
    43621 agctgacgct tggcaaaacg acgggtcgcc tgtttaagac tctcacgagc ttcctcaaag
    43681 gtctgctctc cacggaaata aggaaagagt tccttatagc caattccttt agcagcctgt
    43741 acattagggg aatggtcaaa cagccacttg gcctcatcca aaagcccagc ctcaaacatc
    43801 aaatccactc ggtggttgat acgctcataa agttgactac gttcatcatc caagcagata
    43861 atcagcggtt catacaaaat ctcttgattt tccaaatcct gaccaaaatg ggcaatttct
    43921 aaggcacgca tagcacgacg acgattaaac tggggaatct caaggcctgc ttgctccacc
    43981 aaatgggcta attcctcatc tgaatatggc tccaaactag ctcgataagc taaaatctcc
    44041 tcatgaggag tctccccacc taggtggtaa ccttctagca agctctggat ataaagtcca
    44101 gtcccaccgg cgataatggc tagcttgcca cggctgtgaa tatcctcaat agtcatctta
    44161 gcttctgaaa caaaatcaaa agccgagtaa gactcggtta tctctctaac atcgattaaa
    44221 tgatgaggaa cagctgcctg ctcttctgga ctagccttgg ccgtcccaat atcaagtcct
    44281 cgatagactt gttggctatc tccactaacc acttcgccat taaagcactt tgcaacttca
    44341 atagctagag ccgtctttcc aacagcagtc ggtccaacaa tcacaattat ttttgttttc
    44401 atcttttttc cttgaaaaat tcccattttt tcgttactat tattataaca caaaaaggtc
    44461 agtcagaaaa atgtgacctc ttgaggaggc tggctgattg agaatataaa ggaggaagac
    44521 tcatggctaa aggattcgct aaaggtcttg taacaggtgt cgcaggaact gtcgctgccg
    44581 ttgcaggtgc agtatacgca tttaaaaaga aagtaatcga accagaagag caaaaagcag
    44641 ctttcatcga agaaaaccgt aaaaaagcag ctcgtcgccg cgtatcacgt taagaaacaa
    44701 aagaagttgg gattattctc aacttctttt ttctattctt ttaaatagct aggtcaaact
    44761 tcaactgtgg cttaacaggg tcataatcca ccaactcaaa atcttctgct ttgatatcaa
    44821 agaaattagt cccatcagga acatttaaaa ccaagcgtgg ttggcagttt gacggctccc
    44881 gacggagcaa ttcctgagct tgttcaaatt gattatcata gatatggagg ttgttgatga
    44941 agtagaagaa cttcccaacc ttccagccaa aatgtttggc aatcatcatc tgcaaagcca
    45001 catactgcat agcgttgatg tggtgggcca ccagcatatc attggagcgc tgggtcaagg
    45061 tcgcatccag atagatttcc ccatcaacac gccggacatc aaacatggtc tgaaaggcgc
    45121 acgggagcag cccatctgtt tcttcgaaag cttggtaatc ccagagcgaa ataatattgc
    45181 ggcggttcca aggattggtt tccaactgtt tgagaagctt attgataatg tcgtgtttct
    45241 taacaacggc accatagcgc tcaccaatgg ttcccgtgtc tccaacttcc cagtcattcc
    45301 agtagtgaac attgtacttg tcattaagca cttctaagct atttgactgg tcttggtaaa
    45361 tccagagaac ttctttgatg gcggatttga ttgcaatggg acgcaaggtt gtgataggaa
    45421 attctccttt agataagtcg tactcggaaa aggcaccagt tacatacttg gaattagcaa
    45481 cagtcccatc cttgtactta ggacgagcct gctctgagaa aacaccttcc tttagaatgc
    45541 gttcaatatt ctctttaaaa atcgtatctg cttttgtcat ttcgtttcac ctcattcatt
    45601 gtcctaacta gtatagcata aaaaataaaa gaggaacatt actaactcta ggttagcatt
    45661 ttcctctctc attatcttat tgcaatacaa gtgatgctgc tccgataact ccagcgtcat
    45721 ttcctagagt tgcaagagct aatttagtag atgtgcgtac ttgtgggaaa ctattttcat
    45781 cgtaaacttt ttgaacacct tgtagaagga attctcccgc agctgacaca ccaccaccga
    45841 tgacgattgt tgatgggttt aggattgaac caatgttagc acaagcgatt cccaagtaac
    45901 gtgagaagtt acggtaaaca atcaaagcaa ggtcgtctcc ttcttttgcg agatcaaaga
    45961 cagtcttagc agttacttct tctccgttat caatcaagcg tttcaaggct gcatcgcctt
    46021 cgtattcatc ggcatagcga cgagtcaagt tgacaatccc tgttgctgaa gcaactgtct
    46081 caaggcagcc ttttttacca caagtacatg agattggttg gtcaaagtca acagtgatat
    46141 gaccaagttc acctgctgca ccagcaacac catgaagcaa tttgccttct gcgacaatac
    46201 caccaccaac accagtaccg agtgtcataa agacaacgtc tggttggtta tctccagcac
    46261 ccatccagcg ctcaccaaga gctgctacgt tggcatcatt atcgatgaaa aatggaatgc
    46321 ccaaagcttt ttcaatcttt tgtttgattg gttgaagggt tttccagttc aagttgtagg
    46381 caccgataac agtccctttt tcacggtcaa ccacacctgg tgatcccatt ccaatacctt
    46441 ggaagtccgc tgctgccaat ccaagcaagt ccaaacgatg ttgaatagac tcaatcatat
    46501 catcaacgat atgacttccc tcatccaaaa tgttggtctt gattgaccat tttccttgga
    46561 tttctcctgc tgttgttaag attgcaaatt tgatagaagt tccaccaagg tcaatcccaa
    46621 taatcttttg actcatcata ttctcctttt tcattgtgta gtaattgaaa atgcttacag
    46681 tactagtata tcaaaatcca ttcacttatg caaaggtttg cgtaaatgaa ttataaggaa
    46741 ttttttcgcc taccagtatc tgttaaccat ctaaatgatc aatggcatat tgagctgcat
    46801 catttgaaaa tttatcaaaa tcagaagtta attgtctata catacgtttt tttgacatgt
    46861 ggaataacga attataactt tttgcctttc ctaaagcagc agaatattca ctattgctat
    46921 cattactaga agaagctgta cttgcttgac cttccttcca aactccgtca gcgccaacat
    46981 aataacgtcc accatcaacc cattcattga cagccatttt accatccgat tttagatagt
    47041 aatttccttg ccatgtactg taagcataag aaccatctga tgtcaaataa taccaagctt
    47101 gataggtggc atcataaacc cattcacctt tagccatttt accatctgat ttcaaatagt
    47161 agtttccttg ccatgcattg cgagcatatg aaccatctga tttcaagtaa taccatgctt
    47221 ggtaagaaga atcataaacc cactcacctt gtgccatttt accgtttgat ttaaggtaat
    47281 aagctccttg ccatgtactg taagcataag aaccatctga tgtcaaataa taccaagctt
    47341 gataagaaga gtcataaatc cattcactct gtgccatttt accatcagct ttcaggtaat
    47401 agtttccctg ccatgcattt tcactagatt tccatttcca tcaaaatagt accaagaacc
    47461 gtcctgctta acccaaccac ttgctgtgga tgaagttgta tcagtttgag ttgtagccgc
    47521 ttgttttgct ttaaaagcac ccttaggagc atttttcaat tcgcaagcca caccatcatg
    47581 atcgcggtct aacttggcag aataaccagg ttctccctca tgaagatccg aatatccatt
    47641 agcccaagct tccttacaac tcgaaaaatg aatgttttcc tctgctaaca caggttgtga
    47701 aaacaaggct aaaattggca acgtcaccag actcattttt aaaaatagac gtttattcat
    47761 ttctttctcc cataattatg atatcgattt caatattatt ttatcaaact tatttcagca
    47821 attcaaggaa acttctggtc ttttctacaa actcctttgg ttttgcctta ttcaagacat
    47881 gagggccatc tgggataatc tgaaattggg attctgatat tagtttatga agacttctca
    47941 tagaactaag attcggttta tctttgatac cacaaattag taaggttgga taagggcaag
    48001 ttcctgctat atccgttaaa tcaagtgtct tcaactcctc agaaactccg accataagag
    48061 ccttgtctgc tccctgtttt tcaaatactc ttttgggaag tagtttaaaa atcagcaact
    48121 gaagataaaa taggatattc cctgctaatt taagcgggca tcctgacaga atcaaagctc
    48181 gaagatttgg taaatcgtaa ctggaaagtt ctagtgccag ggcagcacct aaggacaatc
    48241 caatcaaaac aaaaggttct gtctcttgag ctaggtgctg ataaactcgc tccttagctt
    48301 gttgatagtt actaactcca gaaggaaata actcgatagc ctcagaagga taatctgtca
    48361 gtagattccg aacttctttc caagactctg ctgactgccc taacccatgc aaaaatatca
    48421 gtttcatcta gttctcctca aggcttagtt catacaagcc tctcactgca ttacagccgt
    48481 aaatagcttc tgcttgggct aaatctgcca aggtcaagac tttctcttct acctgtcctg
    48541 tttctagcaa atactgacgg taaattcctg gcaagattcc aagtcggata ggcggtgtgt
    48601 agagttttcc agcgattttc agaaccaaat ttcctataga ggtttcaagc agttttcctg
    48661 acttattgtg gtaaatcttc tcttgttctc ctaggctcaa atgcggtcgg tgagtggttt
    48721 taaagtaggt aaaggattga ttcaaagcag cttcctgaag gcagacttgg gcctgacaaa
    48781 agcttgtact gagaggggtt aatacttgac gattgacttc tatctctcca gatttgctaa
    48841 ggctgattcg caagcggtaa tcttgattag cttcacaatc ctgacactct tcctcaatct
    48901 tgtgtcccaa gtcttctgca tcaaaaggaa aggcaaaata acgactagct tttctcagtc
    48961 tttccagatg ttgatcttca aacagcaggt tcttctggct gatttcccct gtcgtaatca
    49021 gttggaagcg ggcttgttta cgataaagaa ctgctgcctt ttgatgaacc tctcggtatt
    49081 cagattccca tgtgctatcc caagtaatcc ctccgccaac tccataaatg gcttgacctt
    49141 tgtgaagttg aatggtacga atggccacat taaaaatccg tcgtccattt ggaagcaaga
    49201 gaccaatcgt tccacagtag actccacgcg gttgaggctc caagtccttg ataatctcca
    49261 ttgtcgcaat tttcggtgca cccgttatgg aaccacaagg aaagagtgag cggaagattt
    49321 caacaaggtc cacatcctct cgcaactgac tcttgatggt cgaagtcatc tgccaaacag
    49381 ttgaatactg ctctacctgg cacagacgct ccacgtgctc gctcccaact tcagaaatac
    49441 ggttcatatc attgcgcaag aggtccacaa tcatcatatt ttcagagcga tttttgggat
    49501 cctgttccaa ccaactggcc tgttcaagat cttcttggtc agttacccca cgctgagtcg
    49561 tccccttcat tggtcgtgtt gtcaactcgc gatcattttg ctcaaaaaag agctctgggc
    49621 tcatggaaat cactgccatc tcgtcatgtt ccacataggc attgtagccc gcctcctgct
    49681 ctaccaccat acgattgtag atggcaaaag gattggcact taacttttgc ttgagttgga
    49741 cggtgtagtt gacctgatag gtgtctccct gcctcaagtg atggtgtatc tgggcaatgg
    49801 ccttttcata gtctgctgca gacgtcactt cctgccaatt tgagggcaaa tcaatatcct
    49861 cataagtcag aggaataggg gaggtctcta ccctatcatg aacagtaaag taaagcaggt
    49921 actctcccag taggggatcc ttgtgaactg ctaatttttc ctcaaaagca ggggcagcct
    49981 cgtagctgac ataccccacc acataataac cttgctcttg gtagctttcc acttgtgcca
    50041 gcaaatctgc cacttctgct acatttctcg tttttatctc tttgataggc tgggtaaagg
    50101 tgtatctctc ccccaaaatc ctaaaatcaa tcactgtttt tctatgcata ccttaagtat
    50161 agcataaaat aagaaaaccc tcatccgcaa agcagatgag agatttcaat tatttaaaga
    50221 ttgaagtttt aaagctattt gtttgttgaa gaagtttctt ataaactttt tcttttactt
    50281 gcacaagttt accattaact ttattagtaa ccatatcttc ttcaagagct ttggcaaata
    50341 atgattttaa ttcatcatag ttatgaatgg tctcaccatc aatagtaaaa ggagtaaaac
    50401 cagcgttggc tttttctaac aattctttat aatattcttt cttaaaatca gcaaacgatt
    50461 ggaatctgcc gtcagatatt ttttgtataa tatattgatc tccaaattgt ttcccttctt
    50521 tattagcttg agattttaat ttatctgaag catatcctaa gaatccttta tcatagccat
    50581 aatatcccca gagtctaaat gcattattct taaatgtaac agcaccgggt gcaccctcac
    50641 ttgtgttacc tgcatagata ctattcatca ttttaattcc tacataggca atacctggat
    50701 caaatacttc tggcttatat atattattat tcatcatacg attagtcatc agattattat
    50761 caactaagtc attaacactg tttaatgtta ttcctttcca atcatcagag ctcatatttc
    50821 gaaccttgtc atattgatct tttgacccta cagtgcgttc aataggatca actttcttaa
    50881 accacagttg atttaattta tcatcatgtt tactaatgac tgcatcacct tcaacataat
    50941 caagaagaga caaggtatct atatagcctt tcatataatt atcaatgtct tctcttgttt
    51001 taagagtctt cggatcggta atataccact gatttccatc atttggacga tagaaagtca
    51061 tattaattcc caaagcaccg tattcatcaa accatgtact tggtactggt gtttgtaaca
    51121 ttccttgtgc ataggcttct gcatgagtcc ctgagcgacg tccatatcct cctaaataga
    51181 ttgcacgatc attaacatga gtagtttcat gtgtataaac agagattcca aactcatcaa
    51241 tcatacttaa tgcaatataa tttacttctg ttcgcgtatc caaaggatta tcccaaataa
    51301 ctgcataagc acctgttcca ttgttaccat aatacttacc aataggtcca aacaactctc
    51361 tcaatggggc atagtcttct ttattatttc tcttaccata cttatcaggc catccaccag
    51421 gtgcttgata accttcccaa agaggagtta ctgtattttt gactagcata ttcttaacct
    51481 tatctaaaga taatctatac caaaaatcaa aataatttcg ataactgtcc gctgcttttt
    51541 caatctgatt ttttattcca tcgaaggagc tatgccctaa cttttctgct gttccaacag
    51601 ccattgcact ataattcgag attaaataca catgtgattt atttagattt aataatggga
    51661 gtatcatctt ccgatgagta gcagattgta aattatccca aactttatat ttcgccgctt
    51721 taatttcatc gacttccgaa gcacgctccg ctatatagac attcccttct gtagctttct
    51781 taaaccaatc ataaatattt acatctgcag taaatagtcg acgattataa tttaaaaagt
    51841 ttaccaaatt ttctgataag gttgtcttag aaataatctc gctgaaagca tcatatgtcc
    51901 gatgaccttt tatattatct tctcttgaac cgatttcaat taatctatct aatacactta
    51961 catttttacc atagaaatct ggtttgaata acattaattc tttaatgtta acatcaccga
    52021 atttaacacc gtagtaacgg tttaagtatg ttaaacctaa taatagggca gctttatttt
    52081 tctcaacttt atcaagaatc atttgttgag ctgcagatga attattcagt tgatgatctt
    52141 cattttcaac taatttagtt actaatatgt ttaaattagc ttttacatgg tcaaaacttt
    52201 cttctaaata aaggtcttta attgcattta ctctattaga ccctgttctg ccaagttttt
    52261 ggtaaattgg attagattga agctcaatag ggcttaagat atttacgata ccgttaatta
    52321 aagcactatg atctttttga acgatattag gtgtatattt aatacctaag tcagttatag
    52381 tgtattctct aacattactt agaccttcat cactagaaga taggttgaag tagtcttttg
    52441 ttccatcagc ataatgaacg ataattttgt ttgcatcacc taaatcagtt acaaagttat
    52501 tattgttcat aggagtaacc gatagaatct ctttagtatt taacttgttg ttcttatcta
    52561 gtttattagc ttgattaacg ataaaatctt tgttatagaa tggttgtagt ttttcaatat
    52621 tcttataagc aagtttatag tctgcattat aatcttgaat agactcgtaa gctgcttcac
    52681 gactgctaac attattcaat ttgttcaatt cataaggttc acttacgaat ttagcagcag
    52741 taatattgaa actagcaact tttgcatcag cctcagattt agataagtgt tttaatttat
    52801 ttttgttttt attatcttta ccagttccat cttcagaaga gctatatcca ataactccaa
    52861 ataaattaga cacaaaagga tttgcatctc catcattaac atcgtttgaa ccgaatattt
    52921 cctgaccttt aataactttc gcatatgtta cattatcttg aaccgctcca tatggccaag
    52981 ttttagaggt tattccacca acatatttag tatttttaac atcaagaata ccttttgcta
    53041 cagagtttgt aagttttcct tttgtccctg atagccagct atgagcttta tattgaacga
    53101 aaggaacaag catacttgca tttgcgttat ttgctgtaat agtagcatca acgtaggctc
    53161 tattaacaaa ccccatatag ttagaaccgg caatacctcc aactgttgaa ttattaccag
    53221 cagaatttat actaccgata aatgccacat tttctaaagt agcgtcttct tttatgttat
    53281 ttacgaaccc agcaacatta tttctagctg ttatggttcc gattgctttg atattttcta
    53341 tacgtgtcgt tccactgatt tcatttgcta ttgcagcgat attatcttga ttagataaat
    53401 caatatcaat attttcaaaa tttatatttt taacagttcc agccttaatc ttatcgaata
    53461 aaggatgttc caaattatgg atagcatagc gtttatcacc atcactcaat agtttaccag
    53521 taaactctga agtaatataa gatttccctt taggaacaac gttacgagcg ctcatgcttt
    53581 gacccagttt aaattcaccg gcaggatttg tctgaatggc ttggatcaat tcttcaaagt
    53641 cgtagaaaat accagcctga ctagctttgg gtttttcaat atagtaggta taagtttctt
    53701 caaagcgatt atcgacatta cgttggacca agttatccgc tactgctatt accttgtaga
    53761 cttgttttcc atcaattgtt gactcttcaa ttttttgaac cgctagtaga ttggtcttat
    53821 ggtcattaga ggtaactttt aaataataat ttgacaaatc agttggcact gaagtcaatc
    53881 gagtttcatc agtttcaact tggttttcat atttgattaa atccgttctt ataatatctt
    53941 ttatttcaac ttttttgaga tcaattctta gcggttcttc tttcagaact tcttcctcat
    54001 ccccctcacc acggtcataa accatctttg tttcaagttt ataatccttg tagtactgca
    54061 aatctgtcag ggtagttgtc aagtcttctg gtgaaacatt caaggttttg acaatctcat
    54121 cacctttttt cagagttagg gtaatagatt taatggctgc cttacttgga ttttctaaac
    54181 tatacttaac atctgaagta cgcttcaaat ccttagattc aatttctgtg atggtcaaca
    54241 ctggtttttc aaagctcttg gtaccacgtt tcaaaatttt gtcttgaggt tcctcaagga
    54301 tttcctctgt aacttttgga gcgtcttctg ttttaactcc cttaatggta ttaaaggtct
    54361 tggtgatttt tttctggcct tcttttcctt cttgagctac aacttctaag ccttttttca
    54421 gttggtcatc ttctttaaca acttccttaa atggaatctt ttcaagactt tcttctataa
    54481 gagttccttc aattggtttt gtaccacgga ttacctgttg atttacaggc tccttggtca
    54541 cttccgtact ggttgaaaga acttggtcag ttttaacacc ttctactgtt ttataggttg
    54601 tttttgtaac ttgacttcct ttttcaccag ttcgtaggac agtttcttcg tccgtatact
    54661 tggttggatc ctcagtcgtt tcagttttgt agtctaggtc tgtagtcgat gtttcaacaa
    54721 gggttccctc agttactttg tactcaggta attgttcttg agcaagagcc tcacccacgt
    54781 gacctttttc ttgcgtacct ttagctgttt tagtctcctc ttttgattct actggttctt
    54841 caaccttgat ttctggggct tctgctggct gttcatcttc ttgtttcggt gtctcttccg
    54901 ctcccctatc ttctttagga ttttcttgtt gtgatgattc ttttggtgta cttggttgct
    54961 cagcttgtgt aggttgcacg ggttgttctg ggacttttgc ttgttctact ggtggttcaa
    55021 cttttgattc ctcagctggt ttgtctgatg gttgactttc tggcttaact gctacttttt
    55081 cctctggttt tgactcaact tctccaccta cttcttcaac tggagctggt tctgctgaat
    55141 cttctttccc ctcttctact ttaggaaggg tgtcgtcagt aggttttacc tccgattttg
    55201 gttcttcctt tggactttct tctgttttag gtgcttcttc ttttggagct tcctctgtct
    55261 ctactacttg gttttctgtc ctagcttgct cctgatttgt tgttgattga ggagtctcaa
    55321 cttcgactac agtcacctct ccaggttttg ctgaggtttc ttctaaaaca gtgtccaagc
    55381 caagcgtttt gaggatgtca cctgatagat aaccaacata gcgatagcca tccatttcaa
    55441 caacaccctc tcgactagcc agcgctaggg tcgcaactgg gtctacagcc cctgcactag
    55501 gaagaactac caatcccata gctccaacta gaaagacgct agcaattttc tttctcttgt
    55561 agattaaaag caagctccca acagtcagca aaccaaaagc tgtcaaaaca gatgcttctg
    55621 tccctgtttg aggaaactga tctttttgat acaccaaacc atatacaact tcattcctgt
    55681 caggctttcc tgtctgaatt aaatctttag cttcttgtga aataatctct ttatttacat
    55741 agtgataggt ggctgcgtcc actacagaag gagccatcaa aaggcttcca agaaatacag
    55801 agcctacaac tcccttaatc ttacgaattg aaaaacggtc ttttttaaac acttttatct
    55861 cctttattca ttctcaagac tttctaatag catcttgcgg atagtgcgca cgcgcacctc
    55921 cgattaattt tggacgacta gccagtgccg ttacatgggc atgaccaatc tctctcaaaa
    55981 tagggcgaat cggaacctga acatgcttga catgcatgcc aattgcagtg tctccgatat
    56041 ccaatccagc atgagccttg ataaattcaa cctcaactgg atcctgcata aacttaaagg
    56101 ctgccaactg ccccgaacct cctgcatgaa gagtaggatg gacactgaca atttccagat
    56161 caaactgctc tgccacctga cgttcaacaa cgagagcccg attgacatgc tcacaacctt
    56221 gaactgctaa atggatacct ctactaccta gaatacccaa gatagtctcc actatcagct
    56281 caccaatctc ttgactggat tctttcccaa tctgaccacc tagcacctca ctagaagata
    56341 gacctaaaac aaaaaggacc ccctgcttca aattggtctt ttctaaaaca tcttccacta
    56401 cctgacgtgt ttctctttga atctgtgtct cgttcatctc tgttacctct gttgttactc
    56461 ttctatcata ccgttttttc ttgtttttag caagatagac aacctagaaa gcttgcccaa
    56521 ttacgcataa aactcccaga attgactggg agttagctag tttctattct atttatatat
    56581 atttcaactt tcgtcccttt ttggggtcta gaatcaatct tcatctggta attggctcca
    56641 aaatgaagtt tgagccgttg atcgacattt tgaagaccaa ctcccccacg tttgagttga
    56701 ctttgactac tatcaccagc atcttggaag ccaacgccat catcctcaat acggatgacc
    56761 aatcccgaat cctgtttctg gacagaaagt ttaatatggc cctgaccttc cttttcctta
    56821 atgccatggt aaagagcatt ttctacaagg ggttgtagga ccagcttggg taagactaaa
    56881 ttatcaaagg caacattttc attaatttcg tattccagct tatctccata gcgttgtttc
    56941 tggataaaga gatactggcg gacatgattg atttcgtcag agagacaaat caagtctttg
    57001 ccttgattga gcgccaagcg gaaataggtt gccaaggact tggtcacctg caccactcgc
    57061 tgactatcat gaaattcagc catccagatg atggtgtcca aagtgttata gaggaaatgt
    57121 ggattaatct ggctcgaaag ggcttgaagt tggtactgac gggtcgtttc ttcctggcta
    57181 cgaatagcta ccatcaactg atcaatctga tccaacatgg cattaaattg gcgagttact
    57241 tctctcagtt cataggcacc aacttccttg gcacgaagat tttgagcacc agaagcaatt
    57301 tccaacatgg tttctctcaa atccttcaaa ggagcaatcc agcgtttaag actgaaccac
    57361 actaagcaga gacaaacaag aagagatgtg acactggccc caagcaaggt ccacaagagc
    57421 tgactccgaa cctggtctaa cttttccaat gatgacacgc caagtaccgt ccaatcagtt
    57481 cctgcaatct tctcttgact gacgtaggat ttgtgaccag gagtataacc ctgacctgtc
    57541 tcgatgtagg gtttcatagc ctccattttg ctagacgaac tataaactgt gtgttgagga
    57601 tggtagacaa attcatggtt ttcattgata atgaaggcaa agccctgctg ccccaactgg
    57661 agttgattga gataggcttc cagagtttca taagaaatat ccaaacgaag cacaccaaga
    57721 ttggctccct ttgcatcaac aagttcttga gtgacagaaa tgacccactg actatctgat
    57781 ttacgagctg gagtcaaaac aggcatagct ccctgatgaa tagccttttg gtaccaatcc
    57841 tcagccatca tatcagagga agttttcatc tgcacactgt catctgtaga aatgacctga
    57901 ccagatttgg tcaccagcac aacagttttc aagtccttat ctgacttcaa gatggtcaaa
    57961 aacaaatctc ggattccctc gaccttgtct tgactgggat tctcagcata ggccagaaca
    58021 tccgtctgct gggtcaaacc agtcgaggtg gtttctagtt ttttgatata agactgaata
    58081 aagtggctag tctggctgat ggtcgtttgg ctgttgccct caatggtggc ctcaatggct
    58141 gaagaacttg attgatagta gaaagttcca accagagcta ggagaatgag aaagaccaga
    58201 aagatggaaa taaccattct aactaaaaga gaagaacgct tcatcggtct tctcccttct
    58261 taaactgacg aggtgtcaca cctgcaatct gcttaaaacg ttgggtaaaa tagttcatat
    58321 cttcaaaacc aaccttctct gcgatctcat aaatcttcag atctgtagtt aaaagcaaga
    58381 gcttggcttg tttaacacgt tctctcacca gataatcctg aaaaggcaag cccaactctt
    58441 tcttaatcaa ggaactcaga taggtcggac taaaacctaa gtcactggct aaagacttta
    58501 aactaaattg gctatcagcc agatgagact ggattttctg ggccatgttt ccttcaaacc
    58561 tattagtcaa taaatcttgt aactgctctt ctttctcttc cttgtctagt ttttgtttga
    58621 ttttccccaa catttcctca atatcctgac gagaaaaggg tttgagcagg tagtcgtcca
    58681 cacctagttt gacagcagac aaggcataat caaaatcatc gtaacctgtt aaaaagacca
    58741 aatgaacctg aggataggtt tctcgtacca gactggccaa ctggatgcca tttagatgag
    58801 gcatgttgat atcggttaaa atgatatctg gcacctgctt ttggatcaat tcccaagcct
    58861 gccttccatt ttcagcctga ccgatgattt ccatatcgta ggctgctaca ttgaccagtt
    58921 tagtcaaacc ttgtcttacc agatattcat cttctacgat taagattgtg taggtcatgc
    58981 tctgctcctt taccacttac tagtatcagt atagcaaaat tctcctctaa ctgcttagga
    59041 aagacctctt atactcaata aaaatcaaaa agtaaactag gaagatagcc acaggtttct
    59101 caaagtatag ctttgaggtt gta
//
LOCUS       DAVBOD010000009        55966 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 640-05
            SAMEA1012484-rid20186543.denovo.009, whole genome shotgun sequence.
ACCESSION   DAVBOD010000009 DAVBOD010000000
VERSION     DAVBOD010000009.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012484
            Sequence Read Archive: ERR059358
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 55966)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 55966)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979948.1
            Genome Coverage       :: 595x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:03:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,266
            CDSs (total)                      :: 2,219
            Genes (coding)                    :: 2,091
            CDSs (with protein)               :: 2,091
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 71 of 128
            Pseudo Genes (incomplete)         :: 50 of 128
            Pseudo Genes (internal stop)      :: 33 of 128
            Pseudo Genes (multiple problems)  :: 22 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..55966
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012484-rid20186543.denovo.009"
                     /strain="NIG 640-05"
                     /db_xref="taxon:1313"
     gene            complement(59..1762)
                     /gene="ilvD"
                     /locus_tag="VQ862_000559"
     CDS             complement(59..1762)
                     /gene="ilvD"
                     /locus_tag="VQ862_000559"
                     /EC_number="4.2.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000137341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxy-acid dehydratase"
                     /protein_id="HET3114952.1"
                     /translation="MTELDKRHRSSIYDSMVKSPNRAMLRATGMTDKDFETPIVGVIS
                     TWAENTPCNIHLHDFGKLAKEGVKSAGAWPVQFGTITVADGIAMGTPGMRFSLTSRDI
                     IADSIEAAMSGHNVDAFVAIGGCDKNMPGSMIAIANMDIPAIFAYGGTIAPGNLDGKD
                     IDLVSVFEGIGKWNHGDMTAEDVKRLECNACPGPGGCGGMYTANTMATAIEVLGMSLP
                     GSSSHPAESADKKEDIEAAGRAVVKMLELGLKPSDILTREAFEDAITVTMALGGSTNA
                     TLHLLAIAHAANVDLSLEDFNTIQERVPHLADLKPSGQYVFQDLYEVGGVPAVMKYLL
                     ANGFLHGDRITCTGKTVAENLADFADLTPGQKVIMPLENPKRADGPLIILNGNLAPDG
                     AVAKVSGVKVRRHVGPAKVFDSEEDAIQAVLTDEIVDGDVVVVRFVGPKGGPGMPEML
                     SLSSMIVGKGQGDKVALLTDGRFSGGTYGLVVGHIAPEAQDGGPIAYLRTGDIVTVDQ
                     DTKEISMAVSEEELEKRKAETTLPPLYSRGVLGKYAHIVSSASRGAVTDFWNMDKSGK
                     K"
     gene            complement(1995..2927)
                     /locus_tag="VQ862_000560"
     CDS             complement(1995..2927)
                     /locus_tag="VQ862_000560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase family protein"
                     /protein_id="HET3114953.1"
                     /translation="MMRSTKELRHVYRDFLLEANQSDSDIVVLEADLSSSMATHNLEK
                     DFGDRYVNVGIMEAEMVGLAAGLSIQGFRPYLHTFGPFASRRVFDQLFISLGYAQLDA
                     TVIGSDAGVTAEMNGGTHMPFEEIGLLRLIPKSIIFEATDDIQFREILNQTLDLKGLK
                     YIRTIRKAPVPVYQGGEDFSKGYIELRHGEDVVIVASGIMVAPSIRVADELSKLGYSV
                     GVIDLFRIKPIPEQIKTMLSGKTIFTVENHNQIGGIGSAVCELFSDDGITKIHRMGVQ
                     ERFGQVGKMDYLLNEYGLSESNIKEKVLEIYNAR"
     gene            complement(2924..3781)
                     /locus_tag="VQ862_000561"
     CDS             complement(2924..3781)
                     /locus_tag="VQ862_000561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HET3114954.1"
                     /translation="MILSKNREDGLRKFATNIRLNTLRTLNHLGFGHYGGSLSIVEVL
                     AVLYGEIMPMTPEIFAARDRDYFILSKGHGGPALYSTLYLNGFFDKEFLYSLNTNGTK
                     LPSHPDRNLTPGIDMTTGSLGQGISVATGLAYGQRIRKSPFYTYAIVGDGELNEGQCW
                     EAIQFASHQQLSNLIVFVDDNKKQLDGFTKDICNSGDFVEKFSAFGFESIRVKGSDIR
                     EIYEGIVQLKQSNNSSPKCIVLDTIKGQGVQELEEMKSNHHLRPTVEEKQMLTSVVER
                     LSQELEETE"
     gene            complement(3785..5131)
                     /locus_tag="VQ862_000562"
     CDS             complement(3785..5131)
                     /locus_tag="VQ862_000562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000975284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HET3114955.1"
                     /translation="MMKFILDIVSTPAILVALIAILGLVLQKKKLPDIIKGGIKTFVG
                     FLVVSGGAGIVQNSLNPFGTMFEHAFHLSGVVPNNEAIVAVALTTYGSATAMIMFAGM
                     VFNILIARFTRFKYIFLTGHHTLYMACMIAVILSVAGFTSLPLILLGGLALGIIMSIS
                     PAFVQKYMVQLTGNDKVALGHFSSLGYWLSGFTGSLIGDKSKSTEDIKFPKSLAFLRD
                     STVSITLSMAVIYIIVAIFAGSEYIEKEISSGTSGLVYALQLAGQFAAGVFVILAGVR
                     LILGEIVPAFKGISERLVPNSKPALDCPIVYTYAPNAVLIGFISSFVGGLVSMAIMIA
                     SGTVVILPGVVPHFFCGATAGVIGNASGGVRGATIGAFLQGILISFLPVFLMPVLGGL
                     GFQGSTFSDADFGLSGIILGMLNQFGSQAGIVIGLVLILAVMFGVSFIKKPSAKEE"
     gene            complement(5144..5428)
                     /locus_tag="VQ862_000563"
     CDS             complement(5144..5428)
                     /locus_tag="VQ862_000563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008089859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HET3114956.1"
                     /translation="MLKIGTACGSGLGSSFMVQMNIESVLSDLNVSDVEVEHYDLGGA
                     DPNAADIWIVGRDLADSASHLGDVRILNSIIDMDELRELITKLCEEKGLI"
     gene            complement(5432..7462)
                     /locus_tag="VQ862_000564"
     CDS             complement(5432..7462)
                     /locus_tag="VQ862_000564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000460919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HET3114957.1"
                     /translation="MFDYRALVILMTLMDHCELSLYELSVKVSLPIKEVKEGIDYLVP
                     YLANKGIVLDKKQGRYSLSNRTKQSLTDIIKSDELVLPKSTRLALIYLYTFCRLDFIS
                     NNHYQDFLKVSKNTTLSDIQSLRKIMLDNDLELGYSRAKGYTLHGSEWNKHRLAFQMV
                     SELLESSIGIWGLDYVLSSWGYSLTYDLINQVVKDYYEKLQLVPIVNQLKVCLFGLVF
                     ILCRYQRDVERVCLSETLVSPVIQDITTILLDTVVDLGIIDTVFSEDDYRYITVLLSS
                     CFEGEVDVAPVYFNQLTEAIISRMEDISLLHFKQREGLRENLRRHLIPAYYRLKFGLP
                     SSNEYVLHVKEHYPDLFELVKDSLMPLMDAIDNPIPDSETAYFVIHFGGYLKKADTLP
                     QKCYKAAIICPNGVSSSLMLKENLLALFPQIEFIGTSKIDDLQVKASSDYDMVFSTIK
                     VETEKPNYLVSVMMTEEQAIQLVELVLKDFPNLEYGDFEIEQILNIVKRYGIITQELE
                     LRLALKNYLYQKNDRKEIVPVLEQLITKETYQVSSQKLGWKEAIRLAAKPLLDQDKIT
                     ENYPEAMIQKVEEFGPFINLGKGVAIPHARPDEGVNEIGMSMLVLEEPIYLLDNPEQE
                     VRLLICIAAIDNESHLKALSHLTTILRDKNHVQTLISSKNYDDIKMIIKQED"
     gene            7653..8660
                     /locus_tag="VQ862_000565"
     CDS             7653..8660
                     /locus_tag="VQ862_000565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HET3114958.1"
                     /translation="MTEKLINSKPNGVFALILIELTIVLGIFIFIMGVGSENIFGIII
                     GPLLIVIAGLAHAGLKVVKPQEALVLTLFGNYTGTIKEPGFYFVNPFSVAVNPANHTR
                     LGQSGDVSTKSPFLGAKSSNDNDVNLEIGKKHISLKVMTLSNSRQKINDCLGNPVEIG
                     IAVTWRVVDTAKAVFNVDNYKEYLSLQCDSALRNIVRIYPYDVSPNVDTTGDGQADEG
                     SLRGSSEIVANRIREEIQSRVEDAGLEILEARITYLAYAPEIAAVMLQRQQASAIIDA
                     RKMIVDGAVGMVEMALERLNEGELVELDEERKAAMVSNLLVVLCGNHDAQPIVNTGSL
                     Y"
     gene            8663..8863
                     /locus_tag="VQ862_000566"
     CDS             8663..8863
                     /locus_tag="VQ862_000566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HET3114959.1"
                     /translation="MAEAKKKQIPLRLSTKLYAALASWAEDDFRSVNGQIEYLLTECV
                     KQRKKDGKYVSETIDEPFEIDI"
     gene            9015..9197
                     /gene="rpmF"
                     /locus_tag="VQ862_000567"
     CDS             9015..9197
                     /gene="rpmF"
                     /locus_tag="VQ862_000567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HET3114960.1"
                     /translation="MAVPARRTSKAKKNKRRTHYKVTAPSVNFDETTGDYSRSHRVSL
                     KGYYKGRKIAKAASAE"
     gene            9213..9362
                     /gene="rpmG"
                     /locus_tag="VQ862_000568"
     CDS             9213..9362
                     /gene="rpmG"
                     /locus_tag="VQ862_000568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001265622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HET3114961.1"
                     /translation="MRVNITLEHKESGERLYLTSKNKRNTPDRLQLKKYSPKLRKHVV
                     FTEVK"
     gene            complement(9784..11664)
                     /locus_tag="VQ862_000569"
     CDS             complement(9784..11664)
                     /locus_tag="VQ862_000569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-N-acetylhexosaminidase"
                     /protein_id="HET3114962.1"
                     /translation="MVRFTGLSPKQTQAIEVLKGHISLPDVEVAVTQSDQASISIEGE
                     EGHYQLTYRKPHQLYRALSLLVTVLAEADKVEIEEQAAYEDLAYMVDCSRNAVLNVAS
                     AKQMIEVLALMGYSTFELYMEDTYQIEGQPYFGYFRGAYSAEELQEIEAYAQQFDMTF
                     VPCIQTLAHLSAFVKWGVKEVQELRDVEDILLIGEEKVYDLIDGMFATLSKLKTRKVN
                     IGMDEAHLVGLGRYLILNGVVDRSLLMCQHLERVLDIADKYGFHCQMWSDMFFKLMSA
                     DGQYDRDVEIPEETRVYLDRLKDRVTLVYWDYYQDSEEKYNRNFRNHHKISHDLAFAG
                     GAWKWIGFTPHNHFSRLVAIEANKACRANQIKEVIVTGWGDNGGETAQFSILPSLQIW
                     AELSYRNDLDSLSAHFKTNTGLTVEDFMQIDLANLLPDLPGNLSGINPNRYVFYQDVL
                     CPILDRHMTPEQDKPHFAQAAETLANIKEKAGNYAYLFETQAQLNAILSSKVDVGRRI
                     RQAYQADDKESLQQIARQELPELRSQIEDFHALFSHQWLKENKVFGLDTVDIRMGGLL
                     QRIKRAESRIEVYLAGQLDRIDELEVEILPFTDFYADKDFAATTANQWHTIATASMIY
                     TT"
     gene            complement(11658..12527)
                     /locus_tag="VQ862_000570"
     CDS             complement(11658..12527)
                     /locus_tag="VQ862_000570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HET3114963.1"
                     /translation="MTIATIDIGGTGIKFASLTPDGKILYKTSISTPENLEDLLAWLD
                     QRLSEQDYSGIAMSVPGAVNQETGVIDGFSAVPYIHGFSWYEALSSYQLPVHLENDAN
                     CVGLSELLAHPELENAACVVIGTGIGGAMIINGRLHRGRHGLGGEFGYMTTLAPAEKL
                     NNWSQLASTGNMVRYVIEKSGHTDWDGRKIYQEAAAGNALCQEAIERMNRNLAQGLLN
                     IQYLIDPDVISLGGSISQNPDFIQDVKKAVDNFVDTYEEYTVAPVIQACTYHADANLY
                     GALVNWLQEEKQW"
     gene            complement(12611..15256)
                     /locus_tag="VQ862_000571"
     CDS             complement(12611..15256)
                     /locus_tag="VQ862_000571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000432759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-mannosidase"
                     /protein_id="HET3114964.1"
                     /translation="MENVVVHIISHSHWDREWYLPFESHRMQLVELFDNLFDLFENDP
                     EFKSFHLDGQTIVLDDYLQIRPENRDKVQRYIDEGKLKIGPFYILQDDYLISSEANVR
                     NTLIGQQEAAKWGKSTQIGYFPDTFGNMGQAPQILQKSGIHVAAFGRGVKPIGFDNQV
                     LEDEQFTSQFSEMYWQGVDGSRVLGILFANWYSNGNEIPVDKDEALTFWKQKLSDVRA
                     YASTNQWLMMNGCDHQPVQKNLSEAIRVANELFPDVIFVHSSFDEYVQAVEGALPEHL
                     STVTGELTSQETDGWYTLANTSSSRIYLKQAFQENSNLLEQVVEPLTIITGGHNHKDQ
                     LTYAWKTLLQNAPHDSICGCSVDEVHREMETRFAKVNQVGNFVKSNLLNEWKGKIATD
                     KAQSDYLFTVINTGLHDKVDTVSTVIDVATCDFKELHPTEGYKKMAALILPSYRVEDL
                     DGHPVEATIEDLGANFEYDLPKDKFRQARIARQVRVTIPVHLAPLSWTTFQLLEGKQE
                     HREGIYQNGVIDTPFVTVSVDDNITVYDKTTHEAYEDFIRFEDRGDIGNEYIYFQPKG
                     TEPIFAELKGHEVLENTDRYAKILLKHELTVPVSADEKLEEEQQGIIEFMKREAGRSE
                     ELTNIPLETELTVFVDNPQIRFKTRFTNTAKDHRIRLLVKTHNTRPSNDSESIYEVVT
                     RPNKPAASWENPENPQHQQAFVSLYDDEKGVTVSNKGLNEYEILGDNTIAVTILRASG
                     ELGDWGYFPTPEAQCLREFEVEFALECHQAQERFSAFRRAKALQTPFTSLQLARQEGS
                     VVATGSLLSHSVLSIPQVCPTAFKVAENEEGYVFRYYNMSQENVRISEHQQTILDLLE
                     RPYPVHSGPLDPQEIRTEFIKKEEI"
     gene            complement(15347..16627)
                     /locus_tag="VQ862_000572"
     CDS             complement(15347..16627)
                     /locus_tag="VQ862_000572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 125 protein"
                     /protein_id="HET3114965.1"
                     /translation="MIYSKEIVREWIDEVAERAKDHPEWVDVFERCYTDTLDNTVEIL
                     EDGSTFVLTGDIPAMWLRDSTAQLRPYLHVAKRDALLRQTIAGLVKRQMTLVLKDPYA
                     NSFNIEENWKGHHETDHTDLNGWIWERKYEVDSLCYPLQLAYLLWKETGETSQFDEIF
                     VAATKEILHLWTVEQDHKNSPYRFVRDTDRKEDTLVNDGFGPDFAVTGMTWSAFRPSD
                     DCCQYSYLIPSNMFAVVVLGYVQEIFAALNLADSQSVIADAKRLQDEIQEGIKNYAYT
                     TNSKGEKIYAFEVDGLGNASIMDDPNVPSLLAAPYLGYCSVDDEVYQATRRTILSSEN
                     PYFYQGEYASGLGSSHTFYRYIWPIALSIQGLTTRDKAEKKFLLDQLVACDGGTGVMH
                     ESFHVDDPTLYSREWFSWANMMFCELVLDYLDIR"
     gene            16798..18882
                     /locus_tag="VQ862_000573"
     CDS             16798..18882
                     /locus_tag="VQ862_000573"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000803403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GH92 family glycosyl hydrolase"
                     /protein_id="HET3114966.1"
                     /translation="MKPLLETIDTRFGTASKHAFSRGNTLPYTGVPFGMNYFVPQTSD
                     QGGSWFFDPHLPIFQGIRLTHQPSPWIGDYSWLLLTPVTSQLGGDSLFHRQSSYDIDK
                     ACFQPHYLKLFSLRYQIETQLTPTCYGASIRLNQKQGKALSLYLHAADELTVEQVDKR
                     TLALRQEGKTETNKNSLTMFTALQMNTDILAISQEAGDWRIDLASSQTEMQLATSFIS
                     PSQALINLPQEDFDSCKTSAQADWENLLHRFDIIETGEADRTFFDHCLYRLFLFPQTF
                     YEVDESGKAIHMDLATGTVKPGVLFSNNGFWDTFRTTFPLFALIIPEHYQRFLEGFLN
                     SYRDTGFLPKWLAPDERGMMPGTLLDGIIADSACKDMAPDLEGELFQAMLETASKADH
                     LGINGRHGLAQYQELGYLSTDHHESVSHTLDYAYSDFCIASCAKKLENIEIAETYKAA
                     SQNYRQLFDAETGYMRARDNQGNFHPDFSPYSWGRDYAECSAIQATLGVLHDIPGLIQ
                     LMGGKETFSNYLLKACQDAPLFETTGYGYEIHEMSEMATAPFGQIAISNQPSFHIPYL
                     FRYSDYPDYTALLIKTLRQKAFHPSWEAYPGDEDNGSLSAWYIWSALGFYPTCPGKPS
                     YDLGIPLFDHLRVYLAKEDKWLDIHTKQNHNHFNFVKECRLNKTLVSTIQHQDLLKAE
                     QLTFTLSWLPSH"
     gene            complement(18922..20601)
                     /locus_tag="VQ862_000574"
     CDS             complement(18922..20601)
                     /locus_tag="VQ862_000574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000721501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-L-fucosidase"
                     /protein_id="HET3114967.1"
                     /translation="MKKIKPHGPLPSQTQLAYLGDELAAFIHFGPNTFYDQEWGTGQE
                     DPERFNPSQLDAREWVRVLKETGFKKLILVVKHHDGFVLYPTAHTDYSVKVSPWRRGK
                     GDLLLEVSQAATEFDMDMGVYLSPWDAHSPLYHVDREADYNAYYLAQLKEILSNPNYG
                     NAGKFAEVWMDGARGEGAQKVNYEFEKWFETIRDLQGDCLIFSTEGTSIRWIGNERGY
                     AGDPLWQKVNPDKLGTEAELNYLQHGDPSGTIFSIGEADVSIRPGWFYHEDQDPKSLE
                     ELVEIYFHSVGRGTPLLLNIPPNQAGLFDAKDIERLYEFATYRNELYKEDLALGAEVS
                     GPALSADFACRHLTDGLETSSWANDADLPIQLELDLGSPKTFDVIELREDLKLGQRIS
                     AFHVQVEVDGVWQEFGRGFTVGHKRLLRGSLVEAQKVRVMITEAQSIPVLTKISLYKT
                     PGLSKKEVVQELAFAEKSLAVAKGENAYFTVKRRECSGPLEAKISIQPGTGVHGVAYQ
                     DEIYVLQFQAGESKKDLHLPTLYFAGDKTLDFYLNLTVDGQLVDQLQVQVS"
     gene            21357..22586
                     /gene="arcA"
                     /locus_tag="VQ862_000575"
     CDS             21357..22586
                     /gene="arcA"
                     /locus_tag="VQ862_000575"
                     /EC_number="3.5.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000094613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine deiminase"
                     /protein_id="HET3114968.1"
                     /translation="MSSHPIQVFSEIGKLKKVMLHRPGKELENLLPDYLERLLFDDIP
                     FLEDAQKEHDAFAQALRDEGIEVLYLEQLAAESLTSPEIRDQFIEEYLDEANIRDRQT
                     KVAIRELLHGIKDNQELVEKTMAGIQKVELPEIPDEAKDLTDLVESEYPFAIDPMPNL
                     YFTRDPFATIGNAVSLNHMFADTRNRETLYGKYIFKYHPIYGGKVDLVYNREEDTRIE
                     GGDELVLSKDVLAVGISQRTDAASIEKLLVNIFKKNVGFKKVLAFEFANNRKFMHLDT
                     VFTMVDYDKFTIHPEIEGDLHVYSVTYENEKLKIVEEKGDLAELLAQNLGVEKVHLIR
                     CGGGNIVAAAREQWNDGSNTLTIAPGVVVVYDRNTVTNKILEEYGLRLIKIRGSELVR
                     GRGGPRCMSMPFEREEV"
     gene            22644..23660
                     /gene="argF"
                     /locus_tag="VQ862_000576"
     CDS             22644..23660
                     /gene="argF"
                     /locus_tag="VQ862_000576"
                     /EC_number="2.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003073325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine carbamoyltransferase"
                     /protein_id="HET3114969.1"
                     /translation="MTNSVFQGRSFLAEKDFTRAELEYLIGLSAHLKDLKKRNIQHHY
                     LAGKNIALLFEKTSTRTRAAFTTAAIDLGAHPEYLGANDIQLGKKESTEDTAKVLGRM
                     FDGIEFRGFSQRMVEELAEFSGVPVWNGLTDEWHPTQMLADYLTVQENFGRLEGLTLV
                     YCGDGRNNVANSLLVTGAILGVNVHIFSPKELFPEKEIVELAEGFAKESGAHVLITED
                     ADEAVKDADVLYTDVWVSMGEEDKFAERVALLKPYQVNMDLVKKAGNENLIFLHCLPA
                     FHDTHTVYGKDVAEKFGVEEMEVTDEVFRSKYARHFDQAENRMHTIKAVMAATLGNLY
                     IPKV"
     gene            23825..24772
                     /gene="arcC"
                     /locus_tag="VQ862_000577"
     CDS             23825..24772
                     /gene="arcC"
                     /locus_tag="VQ862_000577"
                     /EC_number="2.7.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003025409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamate kinase"
                     /protein_id="HET3114970.1"
                     /translation="MANRKIVVALGGNAILSSDPSAKAQQEALVETAKHLVKLIKNGD
                     DLIITHGNGPQVGNLLLQHLASDSEKNPAFPLDSLVAMTEGSIGFWLKNALQNALLDE
                     GIEKNVASVVTQVVVDKNDPAFVNLSKPIGPFYSEEEAKAEAEKSGATFKEDAGRGWR
                     KVVASPKPVDIKEIETIRTLLNSGQVVVAAGGGGIPVVKENNGHLTGVEAVIDKDFAS
                     QRLAELVDADLFIVLTGVDYVFVNYNKPNQEKLEHVNVAQLEEYIKQDQFAPGSMLPK
                     VEAAIAFVNGRPEGKAVITSLENLGALIESESGTIIEKG"
     gene            24983..26494
                     /locus_tag="VQ862_000578"
     CDS             24983..26494
                     /locus_tag="VQ862_000578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004191872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfcC family protein"
                     /protein_id="HET3114971.1"
                     /translation="MSEKAKKGFKMPSSYTVLLIIIAIMAVLTWFIPAGAFIEGIYET
                     QPQNPQGIWDVLMAPIRAMLGTHPEEGSLIKETSAAIDVAFFILMVGGFLGIVNKTGA
                     LDVGIASIVKKYKGREKMLILVLMPLFALGGTTYGMGEETMAFYPLLVPVMMAVGFDS
                     LTGVAIILLGSQIGCLASTLNPFATGIASATAGVGTGDGIVLRLIFWVTLTALSTWFV
                     YRYADKIQKDPTKSLVYSTRKEDLKHFNVEESSSVESTLSSKQKSVLFLFVLTFILMV
                     LSFIPWTDLGVTIFDDFNAWLTGLPVIGNIVGSSTSALGTWYFPEGAMLFAFMGILIG
                     VIYGLKEDKIISSFMNGAADLLSVALIVAIARGIQVIMNDGMITDTILNWGKEGLSGL
                     SSQVFIVVTYIFYLPMSFLIPSSSGLASATMGIMAPLGEFVNVRPSLIITAYQSASGV
                     LNLIAPTSGIVMGALALGRINIGTWWKFMGKLVVAIIVVTIALLLLGTFLPFL"
     gene            26516..27847
                     /locus_tag="VQ862_000579"
     CDS             26516..27847
                     /locus_tag="VQ862_000579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000686986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase"
                     /protein_id="HET3114972.1"
                     /translation="MKIDITNQVKDEFLISLKTLISYPSVLNEGENGTPFGQAIQDVL
                     EKTLEICRDIGFTTYLDPKGYYGYAEIGQGAELLAILCHLDVVPSGDEADWQTPPFEA
                     TIKDGWVFGRGVQDDKGPSLAALYAVKSLLDQGIQFKKRVRFIFGTDEETLWRCMARY
                     NTIEEQANMGFAPDSSFPLTYAEKGLLQVKLHGPGSDQLELEVGGAFNVVPDKANYQG
                     PLYEQVCNGLKETGYDYQSTEQTVTVLGVPKHAKDASQGINAVIRLATILAPLQEHPA
                     LSFLATQAGQDGTGRQIFGDIADEPSGHLSFNVAGLMINHERSEICIDIRTPVLADKE
                     ELVELLTRCAQNYQLRYEEFDYLAPLYVAKDSKLVSTLMQIYQEKTGDNSPAISSGGA
                     TFARTMPNCVAFGALFPGAKQTEHQANECAVLEDLYRAMDIYAEAVYRLAT"
     gene            27942..28069
                     /locus_tag="VQ862_000580"
                     /pseudo
     CDS             27942..28069
                     /locus_tag="VQ862_000580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001836165.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="fucose isomerase"
     gene            complement(28252..28542)
                     /locus_tag="VQ862_000581"
     CDS             complement(28252..28542)
                     /locus_tag="VQ862_000581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000501069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3114973.1"
                     /translation="MGALGYYEGFVPYVSNQYKNQAEEEGKPLSDKYIFEKILGKTYA
                     AFKKDQISERVEKLGKLKPITINYNGKSEVIDSKEKLQELMNKAVKDEVAQI"
     gene            complement(28530..28782)
                     /locus_tag="VQ862_000582"
                     /pseudo
     CDS             complement(28530..28782)
                     /locus_tag="VQ862_000582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000657761.1"
                     /note="The YSIRK form of extended signal peptide directs
                     nascent proteins to the cross-wall site, while signal
                     peptides lacking YSIRK direct proteins instead to the cell
                     pole. A large fraction of YSIRK proteins are surface
                     proteins anchored by sortase-mediated processing of a
                     C-terminal LPXTG motif.; frameshifted; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-type signal peptide-containing protein"
     gene            28986..29063
                     /locus_tag="VQ862_000583"
                     /pseudo
     CDS             28986..29063
                     /locus_tag="VQ862_000583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(29181..30065)
                     /locus_tag="VQ862_000584"
     CDS             complement(29181..30065)
                     /locus_tag="VQ862_000584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001838996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HET3114974.1"
                     /translation="MIFLIVCVLLLVIVTLSTVYVVRQQSVAIIERFGEYQKVANSGI
                     HIRLPFGIDSIAARIQLRLLQSDIVVETKTKDNVFVMMNVATQYRVNEQSVTDAYYKL
                     IRPESQIKSYIEDALRSSVPKLTLDELFEKKDEIALEVQHQVAEEMTTYGYIIVKTLI
                     TKVEPDAEVKQSMNEINAAQRKRVAAQELAEADKIKIVTAAEAEAEKDRLHGVGIAQQ
                     RKAIVDGLAESITELKEANVGMTEEQIMSILLTNQYLDTLNTFASKGNQTIFLPNTPN
                     GVDDIRTQILSALRAEKK"
     gene            complement(30210..31361)
                     /locus_tag="VQ862_000585"
     CDS             complement(30210..31361)
                     /locus_tag="VQ862_000585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase"
                     /protein_id="HET3114975.1"
                     /translation="MATFYVPAVNLIGKGVVNEVGPYIKELGYKKALLVTDKYIEGSD
                     ILPKTLKPLDTEGIEYVIFSDVEPNPTCKNVTDGVAALQEHGCDFIISLGGGSPQDAA
                     SCISIMATNGGKPQDYEGLHKSAKKGLPVVAINTTAGTSAEITINYVITDEERKVKMV
                     MVDKNSLALISVNDPELMLSKPKGLTAATGMDALTHAVEALVTPGAYDVTKKLSIGAI
                     ELIKEYLPRAVENGHDIEAREGMVNAIFLGGMSFNNAGLGYVHSMAHQLGAVYNLPHG
                     VCCAMLLPVIERENAKRVPEAFRNVAKALGLHVEGKSDQECADYAIAEIEKLSETVGI
                     PKKLTELGIEEKDFDFEYLSKNALIDACAPGNPFMPTLEETIAFYKELF"
     gene            complement(31507..33273)
                     /locus_tag="VQ862_000586"
     CDS             complement(31507..33273)
                     /locus_tag="VQ862_000586"
                     /EC_number="5.3.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-fucose isomerase"
                     /protein_id="HET3114976.1"
                     /translation="MIQHPRIGIRPTIDGRRQGVRESLEVQTMNMAKSVADLISSTLK
                     YPDGEPVECVISPSTIGRVPEAAASHELFKKSNVCATITVTPCWCYGSETMDMSPDIP
                     HAIWGFNGTERPGAVYLAAVLASHTQKGIPAFGIYGRDVQEANDTAIPEDVKEKLLRY
                     ARAALATGLMRDTAYLSMGSVSMGIGGSIVNPDFFQEYLGMRNESVDMTEFTRRMDRG
                     IYDPEEFERALKWVKENVKEGFDHNREDLVLSREEKDRQWEFVIKMFMIGRDLMVGNP
                     RLAELGFEEEAVGHHALVAGFQGQRQWTDHFPNGDFMETFLNTQFDWNGIRKPFVFAT
                     ENDSLNGVSMLFNYLLTNTPQIFADVRTYWSPEAVERVTGYTLEGRAAAGFLHLINSG
                     SCTLDGTGQATRDGKPVMKPFWELDESEVQAMLENTDFPPANREYFRGGGFSTRFLTK
                     GDMPVTMVRLNLLKGVGPVLQIAEGYTLELPEDVHHTLDNRTDPGWPTTWFAPRLTGK
                     GAFKSVYDVMNNWGANHGAITYGHIGADLITLASMLRIPVNMHNVPEEDIFRPKNWSL
                     FGTEDLESADYRACQLLGPLHK"
     gene            complement(33330..36446)
                     /locus_tag="VQ862_000587"
     CDS             complement(33330..36446)
                     /locus_tag="VQ862_000587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001031112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="discoidin domain-containing protein"
                     /protein_id="HET3114977.1"
                     /translation="MNKEKIKRKLITILFVCIGMLCFGLLAGVKADNRVQMRTTINNE
                     SPLLLSPLYGNDNGNGLWWGNTLKGAWEAIPEDVKPYAAIELHPAKVCKPTSCIPRDT
                     KELREWYVKMLEEAQSLNIPVFLVIMSAGERNTVPPEWLDEQFQKYSVLKGVLNIENY
                     WIYNNQLAPHSAKYLEVCAKYGAHFIWHDHEKWFWETIMNDPTFFEASQKYHKNLVLA
                     TKNTPIRDDAGTDSIVSGFWLSGLCDNWGSSTDTWKWWEKHYTNTFETGRARDMRSYA
                     SEPESMIAMEMMNVYTGGGTVYNFECAAYTFMTNDVPTPAFTKGIIPFFRHAIQNPAP
                     SKEEVVNRTKAVFWNGEGRISSLNGFYQGLYSNDETMPLYNNGRYHILPVIHEKIDKE
                     KISSIFPNAKILTKNSEELSSKVNYLNSLYPKLYEGDGYAQRVGNSWYIYNSNANINK
                     NQQVMLPMYTNNTKSLSLDLTPHTYAVVKENPNNLHILLNNYRTDKTAMWALSGNFDA
                     SKSWKKEELELANWISKNYSINPVDNDFRTTTLTLKGHTGHKPQINISGDKNHYTYTE
                     NWDENTHVYTITVNHNGMVEMSINTEGTGPVPFPTPDKFNDGNLNIAYAKPTTQSSVD
                     YNGDPNRAVDGNRNGNFNSGSVTHTRADNPSWWEVDLKKMDKVGLVKIYNRTDAETQR
                     LSNFDVILYDNNRNEVAKKHVNNLSGESVSLDFKEKGARYIKVKLLTSGVPLSLAEVE
                     VFRESDGKQSEEDIDKITEDKVVSTNKVATQSSTNYEGVAALAVDGNKDGDYGHHSVT
                     HTKADSNAWWQVDLGEEFTVSKVDIYNRTDAEPQRLSNFDVIFLSSSGEEVFRRHFDK
                     VVDGLLSLKVPSVGAKLVKIELKSAAIPLSLAEVEVYGSKRTPKKLSNIALTKETRQS
                     STDYNGFSRLAVDGNKNGDYGHHSVTHTKGDSPSWWEIDLAQTEELEKLIIYNRTDAE
                     IQRLSNFDIIIYDSNNHEVFKQHIDSLESNNLSIDLKGLKGKKVRISLRNAGIPLSLA
                     EVEVYTYK"
     gene            complement(36456..38750)
                     /locus_tag="VQ862_000588"
     CDS             complement(36456..38750)
                     /locus_tag="VQ862_000588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000780629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 95 protein"
                     /protein_id="HET3114978.1"
                     /translation="MKLWYKKAAANWNEALPIGNGHLGGMIYGSATKECIQLNDETIW
                     YRGKSDRNNPDSLLHLKKIREYLLDGEIQKAEELIKLTMFATPRDQSHYELLGELYIE
                     HIDIQSCALSLYERELDLDTAISNVVFEPNSCNLQIKREYFTSFNKNILCCRIVSSVQ
                     NTLNLNINLGRNKRFNDEVSKLDSSTILMSASAGGRKGVQFKVVCHSKVTDGEVSVLG
                     ETIVIRNATEVFLYLKSMTDYWGNIDISSLQGEFSSIDYFTEKDEHVKKYQEQFNRVD
                     FKLDYSKGCLSIPTNLLLENTKKYSNYLTNLLFHYGRYLLISSSQPNGLPANLQGIWC
                     DELNPIWGSKYTININTQMNYWMVGPCDLPEVEYPLFDMLERMREPGRLTAKKMYGAR
                     GFTAHHNTDGFGDTAPQSHAMGAAIWVLTIPWLCTHIWEHYLYFQDERILTEHFEMIK
                     EAFLFFEDYLFEVDGYLMTGPSVSPENKYRLKNGIEGNACLSSTIDNQILRYFCDSCI
                     GIAKQLGDNSDFISRVKELKKKLPKTKIGSNGQIQEWLEDYEEVEPGHRHISPLFGLY
                     PYNEIDIHKTPELAEAAKITINRRLSNANFLSSQEREQAINNWLVSGLHASTQTGWSA
                     AWLIHFFARLYQGEPAYNQINGLLNNATLGNLFLDHPPFQIDGNLGLVSGICELLVQS
                     HHNWLSLIPALPSAWSEGEVKGFRVRGGYKVSFAWKNGDITFLKLEGGNKDQKVRVRI
                     YGKNTDVQNIELVFNSEKIIELNF"
     gene            complement(38809..39609)
                     /locus_tag="VQ862_000589"
     CDS             complement(38809..39609)
                     /locus_tag="VQ862_000589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HET3114979.1"
                     /translation="MMNNKVTKVELKKVFKRSFMYGSSWNYERMQNLGFLYTILPVLK
                     KLYPDKDSASPAMKRHLEFFNTHQTAAPFILGVTSAMEEQEGNEGAASITGIKVGLMG
                     PLAGLGDSLFWLTLVPICFSIGASYSKDGGALGIFIALILFNIINIPVKYFGLKYGYT
                     KGSSLIQENNTKGTLNRVTSMATALGLVLVGGLIPSMVGINFGLEFKQGELVISVQEM
                     ITKLIPGFIPMALTLLMCKLIRKGKNPVVLIFSVMAIGVILVVLGILK"
     gene            complement(39606..40379)
                     /locus_tag="VQ862_000590"
     CDS             complement(39606..40379)
                     /locus_tag="VQ862_000590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000899624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HET3114980.1"
                     /translation="MLFTQALLVTLVGIIATIDYNGPLFMIHRPLVTSAMVGLVLGDF
                     TQGVLIGSALELTWLGVTGIGGYTPPDTISGAIIGTAFGILSGQGETAGIAIAVPIAV
                     ATQQLDVLAKTLDVYFVKKADNDAKNGDYSKIGFYHYSSLVLITLFKIVPIFLAIMLG
                     GEYVADLFAKVPPIVMQGLNSAGALLPSIGFGMLLNMMLKKNMWVFLLIGFICSVYGG
                     MSTIGISLVGIAVAYFYDMIGSKPQETTSSSDVEEDLDL"
     gene            complement(40404..40874)
                     /locus_tag="VQ862_000591"
     CDS             complement(40404..40874)
                     /locus_tag="VQ862_000591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000020992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HET3114981.1"
                     /translation="MSIEFVRIDDRLVHGQVVTTWLKKYDIEQVIIVNDRISEDKTRQ
                     SILKISAPVGLKIVFFSVKRFVEVLNSVPIKKRTMLIYTNPKDVYDSIEGNLKLEYLN
                     VGQMSKTEENEKVTGGVALGEEDKYYFKKIVDKGTRVEIQMVPNDKVTMLEKFL"
     gene            complement(40865..41296)
                     /locus_tag="VQ862_000592"
     CDS             complement(40865..41296)
                     /locus_tag="VQ862_000592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000483177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HET3114982.1"
                     /translation="MFNRGILVASHGNFASGALMTAEMFVGETTNDRVRTLGLMPGEN
                     IVEFEHYFKNQVNELLDSNQEVIVLTDLIGGSPNNVALSRFLNLDSVDIVTGFNIPLL
                     VELISSYDSKINLEEIVQNAQNSLFNVKQQLNVEEEEDLCL"
     gene            complement(41289..41729)
                     /locus_tag="VQ862_000593"
     CDS             complement(41289..41729)
                     /locus_tag="VQ862_000593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000912112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RbsD/FucU family protein"
                     /protein_id="HET3114983.1"
                     /translation="MLKHIPKNISPDLLKTLMEMGHGDEIVLADANYPSASCANKLIR
                     CDGVNIPELLDSILYLMPLDSYVDSSIQFMNVVSGDDIPKIWGTYRQMIEGHGTDLKT
                     ITYLRREDFYERSKKAYAIVATGETSLYANIILKKGVVVERENV"
     gene            complement(41741..42379)
                     /locus_tag="VQ862_000594"
     CDS             complement(41741..42379)
                     /locus_tag="VQ862_000594"
                     /EC_number="4.1.2.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001286141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-fuculose-phosphate aldolase"
                     /protein_id="HET3114984.1"
                     /translation="MSDVKQELIKYGKKLVETDLTKGTGGNLSVFDREKQLMAITPSG
                     IDFFEIKESDIVVMDINGNVVEGERLPSSEWYMHLIQYQTRDDIDAIIHAHTTYATVL
                     ACLREPLPASHYMIAVAGKDVRVAEYATYGTKELAVNAAKAMEGRRAVLLANHGILAG
                     AQNLLNAFNIVEEVEYCAKIYCLAKNFGEPVVLPDEEMELMAEKFKTYGQRK"
     gene            complement(42494..43897)
                     /locus_tag="VQ862_000595"
     CDS             complement(42494..43897)
                     /locus_tag="VQ862_000595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000388528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnulokinase"
                     /protein_id="HET3114985.1"
                     /translation="MEAVLAIDLGATSGRAIVGYLSENKLVMEEINRFSNLPIRVKGH
                     LSWDIDFLLAKILESIRLANTSYKILSIGIDTWGVDFGLIDNEGKLLLQPVHYRDERT
                     KGVLKEISEMTELEKLYSETGNQIMEINTLFQLFKARQESPDSFYKTNKILLMPDLFN
                     YLLTGKFATEKSIASTTQLFDPRSQNWNQNILKLFELDSSLLPEIVSEGNVLGRIKKE
                     YGLGDIPVVNVCSHDTASAIVSVPKTEGSLFISSGTWSLVGVELTSPLLTTESFSYGF
                     TNEVGKDGVITFLKNCTGLWIIEELRRSFERRGKAYSFDDIRTMVEKEKENLPLIDTE
                     STEFATESDMHKTLTEYLAYHHETREWTDGQLFKIVYESLAETYRKAIELLEELTHKV
                     YKRIYVIGGGARASYFNQMIADRTGKEVLTGLTEATAVGNIVVQLIAMGQLKGMEEAH
                     HVIEEFLQLESYYSQKN"
     gene            44073..44846
                     /locus_tag="VQ862_000596"
     CDS             44073..44846
                     /locus_tag="VQ862_000596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000588554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HET3114986.1"
                     /translation="MIKDERVLELIEIIKKKKRIAVKELAEITFSSTSTLRRDLIFLE
                     NQGLIKRKHGYVTLSSMNTIELSHQIREGESTRQKRLIASLAKDFIRSGMCVYLDSST
                     TVYELCPYLSELDNLIIFTNGLHTAQTLSETVKDSSKIFITSGEVKHQSCSVVNYDKE
                     NSLLDHFNIDLAFCSARGIDDQYVYEASLSQAISKKNIIDKAHETILLIDSSKFYKTG
                     FFKINPLSKYTTFISDTVPDQKLLDAVELFDGEWVSDIQ"
     gene            complement(46008..47513)
                     /gene="adcA"
                     /locus_tag="VQ862_000597"
     CDS             complement(46008..47513)
                     /gene="adcA"
                     /locus_tag="VQ862_000597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000724057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding
                     lipoprotein AdcA"
                     /protein_id="HET3114987.1"
                     /translation="MKKISLLLASLCALFLVACSNQKQADGKLNIVTTFYPVYEFTKQ
                     VAGDTANVELLIGAGTEPHEYEPSAKAVAKIQDADTFVYENENMETWVPKLLDTLDKK
                     KVKTIKATGDMLLLPGGKEEEGDHDHGEEGHHHEFDPHVWLSPVRAIKLVEHIRDSLS
                     ADYPDKKETFEKNAAAYIEKLQALDKAYAEGLSQAKQKSFVTQHAAFNYLALDYGLKQ
                     VAISGLSPDAEPSAARLAELTEYVKKNKIAYIYFEENASQALANTLSKEAGVKTDVLN
                     PLESLTEEDTKAGENYISVMEKNLKALKQTTDQEGPAIEPEKAEDTKTVQNGYFEDAA
                     VKDRTLSDYAGNWQSVYPFLEDGTFDQVFDYKAKLTGKMTQAEYKAYYTKGYQTDVTK
                     INITDNTMEFVQGGQSKKYTYKYVGKKILTYKKGNRGVRFLFEATDADAGQFKYVQFS
                     DHNVAPVKAEHFHIFFGGTSQEALFEEMDNWPTYYPDNLSGQEIAQEMLAH"
     gene            complement(47523..48329)
                     /locus_tag="VQ862_000598"
     CDS             complement(47523..48329)
                     /locus_tag="VQ862_000598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HET3114988.1"
                     /translation="MLSLLSYDFIQRAFLAVIAMSLFSPVLGTFLILRRQSLMSDTLS
                     HVSLSGVAFGLVLGISPTVSTIAIVLIAAVFLEYLRTVYKSFMEIGTAILMSTGLAVS
                     LIVMSKGKSSSSMSLDQYLFGSIVTISEEQVISLFVIAAVVLILTFLFLRPMYILTFD
                     EDTAFVDGLPVRTMSILFNMVTGVAIALMIPAAGALLVSTIMVLPASIALRLGKNFKS
                     VMLLASAIGFLGMVAGLYISYYAETPASASITIIFVTVFILISLVRRFIK"
     gene            complement(48322..49026)
                     /locus_tag="VQ862_000599"
     CDS             complement(48322..49026)
                     /locus_tag="VQ862_000599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001269494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HET3114989.1"
                     /translation="MRYITVEDLSFYYDKEPVLEHINYCVDSGEFVTLTGENGAAKTT
                     LIKASLGILQPRIGKVAISKTNTQGKKLRIAYLPQQIASFNAGFPSTVYEFVKSGRYP
                     RKGWFRRLNAHDEEHIKASLDSVGMWEHRDKRLGSLSGGQKQRAVIARMFASDPDVFI
                     LDEPTTGMDAGSKNEFYELMHHSAHHHGKAVLMITHDPEEVKDYADRNIHLVRNQDSP
                     WRCFNVHENGQEVGHA"
     gene            complement(49026..49466)
                     /gene="adcR"
                     /locus_tag="VQ862_000600"
     CDS             complement(49026..49466)
                     /gene="adcR"
                     /locus_tag="VQ862_000600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001249319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-dependent transcriptional regulator AdcR"
                     /protein_id="HET3114990.1"
                     /translation="MRQLAKDIDAFLNEVILQAENQHEILIGHCTSEVALTNTQEHIL
                     MLLSEESLTNSELARRLNVSQAAVTKAIKSLVKEGMLETSKDSKDARVIFYQLTDLAR
                     PIAEEHHHHHEHTLLTYEQVATQFTPNEQKVIQRFLTALVGEIK"
     gene            complement(49621..50889)
                     /gene="dltD"
                     /locus_tag="VQ862_000601"
     CDS             complement(49621..50889)
                     /gene="dltD"
                     /locus_tag="VQ862_000601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000919885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltD"
                     /protein_id="HET3114991.1"
                     /translation="MLKRLWMIFGPVLIAGLLVFLLIFFYPTEMHHNLGAEKRSAVAT
                     TIDSFKERSQKVRALSDPNVRFVPFFGSSEWLRFDGAHPAVLAEKYNRSYRPYLLGQG
                     GAASLNQYFGMQQMLPQLENKQVVYVISPQWFSKNGYDPAAFQQYFNGDQLTSFLKHQ
                     SGDQASQYAATRLLQQFPNVAMKDLVQKLASKEELSTADNEMIELLARFNERQASFFG
                     QFSVRGYVNYDKHVAKYLKILPDQFSYQAIEDVVKADAEKNTSNNEMGMENYFYNEQI
                     KKDLKKLKDSQKSFTYLKSPEYNDLQLVLTQFSKSKVNPIFIIPPVNKKWMDYAGLRE
                     DMYQQTVQKIRYQLESQGFTNIADFSKDGGEPFFMKDTIHLGWLGWLAFDKAVDPFLS
                     NPTPAPTYHLNERFFSKDWATYDGDVKEFQ"
     gene            complement(50882..51121)
                     /gene="dltC"
                     /locus_tag="VQ862_000602"
     CDS             complement(50882..51121)
                     /gene="dltC"
                     /locus_tag="VQ862_000602"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005591431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltC"
                     /protein_id="HET3114992.1"
                     /translation="MDIKSEVIEIIDELFMEDVSDMMDEDLFDAGVLDSMGTVELIVE
                     IENRFDIRVPVTEFGRDDWNTANKIIAGIVELQNA"
     gene            complement(51135..52379)
                     /gene="dltB"
                     /locus_tag="VQ862_000603"
     CDS             complement(51135..52379)
                     /gene="dltB"
                     /locus_tag="VQ862_000603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000969717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltB"
                     /protein_id="HET3114993.1"
                     /translation="MMEFFQQLPHLEPYGNPQYFVYVIAATLPIFIGLFFKKRFAWYE
                     VLVSLFFIVTMLVGGKTNQLAALGIYLCWEILLLLFYKHYRKSKDGKWVFYLVSFLSL
                     LPIIFVKVQPAINGTQSLLGFLGISYLTFRSVGIVIELRDGVIKDFTLWEFLRFLLFM
                     PTFSSGPIDRFKRFNENYQAIPERDELMDMLDESVRYIMWGFLYKFILAHVLGETLLP
                     PLKNLALQSGGFFNLYALAVMYTFGLELFFDFAGYSMFALAISNLMGIRSPINFNKPF
                     LSRDLKEFWNRWHMSLSFWFRDFVFMRMVMVLTRKKVFKNRNVTSSMAYIVNMLIMGF
                     WHGVTWYYIAYGLFHGLGLVINDAWVRKKKTLNKERKKAGKAALPENRWIQLLGMVVT
                     FHVVMLSFLIFSGFLNNLWFKK"
     gene            complement(52376..53926)
                     /gene="dltA"
                     /locus_tag="VQ862_000604"
     CDS             complement(52376..53926)
                     /gene="dltA"
                     /locus_tag="VQ862_000604"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012972622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltA"
                     /protein_id="HET3114994.1"
                     /translation="MSNKPIADMIETIEHFAQTQPSYPVYNVLGQEHTYGDLKADSDS
                     LAAVIDQLGLPEKSPVVVFGGQEYEMLATFVALTKSGHAYIPIDSHSALERVSAILEV
                     AEPSLIIAISAFPLEQVSTPMINLAQVQEAFAQGNNYEITHPVKGDDNYYIIFTSGTT
                     GKPKGVQISHDNLLSFTNWMITDKEFATPSRPQMLAQPPYSFDLSVMYWAPTLALGGT
                     LFTLPSVITQDFKQLFAAIFSLPIAIWTSTPSFADMAMLSEYFNSEKMPGITHFYFDG
                     EELTVKTAQKLRERFPNARIINAYGPTEATVALSAVAVTDEMLATLKRLPIGYTKADS
                     PTFIIDEEGNKLPNGEQGEIIVSGPAVSKGYMNNPEKTAEAFFEFEDLPAYHTGDVGT
                     MTDEGLLLYGGRMDFQIKFNGYRIELEDVSQNLNKSRFIESAVAVPRYNKDHKVQNLL
                     AYVILKDGVREQFERDIDITKAIKEDLTDIMMSYMMPSKFLYRDSLPLTPNGKIDIKG
                     LINEVNKR"
     gene            complement(53947..54078)
                     /locus_tag="VQ862_000605"
     CDS             complement(53947..54078)
                     /locus_tag="VQ862_000605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000813667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="teichoic acid D-Ala incorporation-associated
                     protein DltX"
                     /protein_id="HET3114995.1"
                     /translation="MKQRKELYLFLGRTALYFLIFLGLLYFFSYLGQGQGSFIYNEF"
     gene            complement(54392..55570)
                     /locus_tag="VQ862_000606"
     CDS             complement(54392..55570)
                     /locus_tag="VQ862_000606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000071468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HET3114996.1"
                     /translation="MSNSFVKLLVSQLFANLADIFFRVTIIANIYIISKSVIATSLVP
                     ILIGISSFVASLLVPLVTKRLALNRVLSLSQFGKTILLAILVGMFTVMQSVAPLVTYL
                     FVVAISILDGFAAPVSYAIVPRYATDLGKANSALSMTGEAVQLIGWGLGGLLFATIGL
                     LPTTFIILVLYIISSFLMLFLPNAEVEVLESETNLEILLKGWKLVARNPRLRLFVSAN
                     LLEIFSNTIWVSSIILVFVTELLNKTESYWGYSNTAYSIGIIISGLIAFRLSEKFLAA
                     KWESILFPLVAMAIVTLTILYFPNAQMFLLFSALVGMLSQLKEVPESVFLQETVEENH
                     LVNVYSVLEVISTLAFSVFVLLMSYITESFGISISFWLSAICLMIEAILIYIRRDYFK
                     "
BASE COUNT        16922 a        12141 c         9961 g        16942 t
ORIGIN      
        1 aaccatacct acggcaaggc gacgttgacg tgatttgaag agattttcga gtatgagttt
       61 attttttacc tgacttgtcc atattccaga agtctgtcac ggctccgcgt gaagcagatg
      121 atacgatgtg ggcatattta ccgaggacac cacggctgta aagtggtggc aaggttgttt
      181 ctgccttgcg tttttcaagt tcttcttcgg atacggccat ggaaatttct ttggtatctt
      241 ggtcaaccgt aacgatatcg ccggtacgga gataggcaat tggtccacca tcctgagctt
      301 caggagcgat atgtccaaca accagaccat aagtaccacc agagaaacgt ccgtccgtca
      361 agagggccac cttatctccc tgacctttac caacaatcat tgaagaaagt gacagcatct
      421 caggcatacc aggaccacct ttaggtccaa caaaacgaac aacgactaca tcgccatcaa
      481 cgatttcatc tgtcagaacg gcctgaatcg catcttcttc tgagtcaaag accttagctg
      541 gcccaacgtg acgacgcact ttaacacctg ataccttggc aactgcaccg tcaggagcaa
      601 ggttcccgtt caagatgata agcggaccat ccgcacgttt tggattttca agtggcatga
      661 taactttttg gcctggagtc aagtctgcaa agtcagccaa gttttcagct acagtcttac
      721 cagtacatgt gatgcgatct ccgtgaagga aaccatttgc caacaagtac ttcataaccg
      781 cagggacacc accgacttcg tagaggtctt ggaagacata ctgaccagat ggtttcaagt
      841 cggccaagtg aggcacacgt tcttgaatcg tattgaagtc ctcaagtgac aagtcaacat
      901 ttgcggcatg ggcaatggcg agcaagtgaa gagtggcgtt tgtagaacca ccgagagcca
      961 tcgttacagt gatagcatct tcaaaggctt cacgagtcaa gatatctgat ggtttgagac
     1021 caagttccaa catcttaaca acagcacgtc ctgctgcttc gatatcttct ttcttatcag
     1081 ctgattcagc tgggtgagag gatgaccctg gcaaactcat ccctagaact tcgatagcag
     1141 ttgccatggt attagcagta tacataccac cacaaccacc agggccaggg caggcattac
     1201 attcaagacg tttcacgtcc tcagctgtca tgtcaccgtg gttccatttt ccgatacctt
     1261 caaagacaga aaccaagtcg atatctttac catcaagatt tcccggtgca atagttccac
     1321 cataggcgaa aatggctggg atatccatgt tggcaatagc aatcatagat ccaggcatgt
     1381 tcttgtcaca gccaccgata gcgacaaagg catcgacgtt gtgaccactc atagccgcct
     1441 cgatggagtc cgcgataatg tcacgagatg ttagagagaa acgcatacca ggcgttccca
     1501 tagcgatccc gtctgctacg gtaatggttc caaactgtac aggccaagcg cctgcagatt
     1561 tgacaccttc tttagccagt ttcccgaaat catgcaagtg aatgttacat ggtgtatttt
     1621 ctgcccaagt cgaaatcact cccacaatcg gtgtttcaaa gtccttatct gtcataccag
     1681 tcgcacgaag catagcacgg ttaggtgatt taaccatgct gtcataaatg ctactgcggt
     1741 gacgtttatc taattcagtc atcttatccc tcccatttca gtttttacta ttatagcaca
     1801 atttaaaggc aatgaacaga ataaaattct tgaattttca gaaaattcta tacgcatgtg
     1861 aaatatttaa aattaaaaac aacaaagcgg attagtgcac tttctgatga ccagaatatg
     1921 ctttttaatc cgctttcttt aaataacgta ctgtaatttt tacagaaatt ctttcaaata
     1981 agtgtattta acatctatct tgcattataa atttctagaa ccttctcttt tatattcgat
     2041 tcactcaaac catactcatt aagaagataa tccattttcc ctacttgacc aaatctttct
     2101 tgaacaccca tccgatgaat ttttgttatt ccatcatcag agaataattc acatacagca
     2161 ctgccaattc cacctatctg attgtggttt tctacagtaa atatagtttt tccacttaac
     2221 attgttttta tctgttctgg tatcggtttg attctaaata aatctatcac acctactgaa
     2281 taacctaatt tagacagttc atctgcaact cgaatacttg gagcaaccat tatgccagaa
     2341 gcaacgatta caacatcttc accatgcctt aactcaatgt agcctttaga aaaatcttct
     2401 ccaccttgat acacaggaac tggagctttt ctaattgttc gaatatattt tagtcctttt
     2461 aagtctaatg tctggttcaa tatttcacga aattggatat catcagttgc ttcaaaaatg
     2521 atcgatttag gaattaaacg taacaatcca atttcttcaa atggcatatg tgtcccacca
     2581 ttcatttctg cagttactcc tgcatctgat ccaatcacag tggcatccaa ttgtgcgtat
     2641 ccaagagaaa taaataattg atcaaatact cttcgtgaag caaaaggacc aaatgtatga
     2701 agataaggtc taaacccctg aatagacaag cctgctgcaa ggccgaccat ttctgcttcc
     2761 ataatcccaa cattcacata acggtctcca aagtcctttt caagattatg agtagccatc
     2821 gaacttgaca aatcggcttc taagactact atatcagaat cactttgatt agcctctaaa
     2881 aggaagtctc tatatacatg ccgtaattct ttcgtacttc tcatcattct gtttcctcca
     2941 attcctgact taatctttct acaactgaag ttaacatttg tttctcctct acagtagggc
     3001 gaagatgatg attggatttc atttcttcca gctcttgaac cccttgacct ttaatagtat
     3061 ctaatacaat gcacttaggt gatgaattat ttgactgttt taattggaca atcccttcat
     3121 aaatttctct aatatctgaa cctttgaccc taatggattc aaatccaaat gctgaaaatt
     3181 tttctacgaa atcacctgaa ttacaaatat cctttgtaaa accatctaat tgttttttgt
     3241 tatcatcaac aaatacaatt aagttggata actgttgatg agaagcaaac tgtatagcct
     3301 cccaacattg tccctcattt aactcaccat ctccaacaat agcgtaagta taaaagggac
     3361 tctttcttat tctctgacca tatgcaagtc cagttgcaac actaattcct tgtcctaaag
     3421 agcccgttgt catatctatg cctggcgtta gatttctatc aggatgagac ggtaatttgg
     3481 ttccatttgt atttaaagaa tataagaatt ctttgtcaaa gaaaccattc aaatagagtg
     3541 tactgtatag agctggtcct ccatgacctt ttgataatat gaaataatct ctatctcgtg
     3601 ctgcaaatat ttctggagtc attggcatta tttcaccata aagcactgct aacacttcta
     3661 cgatagacaa acttcctccg taatgtccga atccaagatg attcaatgtt ctaagagtat
     3721 ttaatcggat gttagtcgca aattttctta acccatcttc tctattttta cttaaaatca
     3781 tcccttattc ctcctttgca gatggctttt taataaagga tactccaaac ataactgcta
     3841 aaataagaac aagaccaatc acaatgcctg cttgtgagcc aaattgattt aacattccta
     3901 aaataattcc tgatagacca aaatctgcat ctgagaaagt tgatccttgg aaaccaagtc
     3961 ctcccaaaac tggcattaaa aagactggaa gaaaactgat taaaatacct tgtaaaaatg
     4021 ctccaatagt ggctccacga acaccaccag atgcattccc aatgacacct gcagtcgctc
     4081 cacagaagaa atgaggcaca acgcctggta agataacaac cgttcctgaa gcaatcataa
     4141 ttgccatact tactaaacca ccaacaaaac tagagataaa tccaattaga actgcattgg
     4201 gtgcataagt ataaacaatc ggacaatcca aagcaggttt tgaattaggt acaagacgct
     4261 ctgaaatacc tttaaaggct ggaacaattt cgcccaaaat aaggcgaaca cctgctaaaa
     4321 taacaaatac ccctgctgca aattgacctg ctaattgtaa agcataaact agaccacttg
     4381 taccactact gatttctttt tctatatatt ctgaccctgc aaagatagct acaataatgt
     4441 aaataactgc catggataaa gtgatactaa cagtactatc acgtaaaaaa gctaaactct
     4501 ttggaaattt aatgtcctct gttgattttg atttgtcacc gataaggcta ccagtaaaac
     4561 cactcaacca atatcccaaa gaactgaaat gacctaaagc taccttgtca tttccagtta
     4621 attgaaccat atatttttgc acaaatgctg gggaaatact cataataata ccgagtgcta
     4681 atcctcctag taagataaga ggcaagctag taaagccagc aactgataaa atgaccgcaa
     4741 tcatacatgc catatataga gtgtggtgcc ctgttaaaaa aatatattta aatcgagtaa
     4801 aacgagcgat taagatattg aacaccatgc ctgcaaacat aatcattgca gtagctgagc
     4861 catatgttgt taaagctaca gctacaattg cttcattatt cggcacaacg ccagataaat
     4921 gaaaagcatg ctcaaacatg gtaccaaatg gatttaaaga attttgtaca attcctgcac
     4981 caccagatac aactaagaaa ccaacaaagg tcttaattcc acctttaata atatcaggta
     5041 atttcttctt ctgaagaact aatcctaaaa ttgcaattaa agctactaaa atagctggtg
     5101 tactaacaat atccaatatg aacttcatca tgacgctagc ctcctatata agtccttttt
     5161 cttcacaaag tttagtaatt aattctcgta gttcatccat atcaataata ctatttaaga
     5221 tacgaacatc tccaagatga ctagctgaat cagctagatc acgaccaaca atccaaatat
     5281 cagctgcatt tggatctgct ccacctaaat cataatgttc aacttctaca tccgaaacat
     5341 tcaaatcact caatacagat tcaatattca tctgtaccat aaaacttgaa cctaatcctg
     5401 aaccacaagc tgtaccaatt tttaacatta tctaatcctc ctgtttaatt atcattttaa
     5461 tgtcatcata gttttttgat gatattaaag tttgaacatg atttttatct cttaaaattg
     5521 ttgttaaatg tgacaaagcc tttaaatgac tctcattatc aatggctgca atacaaatca
     5581 acaatcttac ctcttgttct ggattatcca ataaataaat cggttcttcc aaaactaaca
     5641 ttgacattcc tatttcattc acaccttcat ctggccgagc gtgaggaatt gctactccct
     5701 tccctaaatt aataaaaggt ccaaactctt ctactttttg aatcattgcc tcagggtagt
     5761 tctcagttat cttatcttga tccaaaagcg gtttagctgc taaacgaatc gcctccttcc
     5821 atcctaattt ttgcgaacta acctgatagg tttctttggt aataagttgt tctagcactg
     5881 gtacaatttc ctttctatca tttttttgat aaagataatt ctttaacgcc aatcttaatt
     5941 ccaattcttg tgtaataatt ccatatcttt tgacaatatt caggatttgt tcaatctcaa
     6001 aatctccata ctctaaattc ggaaaatctt ttaacactag ttctactagt tgtattgctt
     6061 gctcttcagt catcataacc gaaactagat aatttggctt ttctgtctcc acctttatgg
     6121 tagaaaaaac catatcatag tcactactag ctttcacctg taaatcatca atctttgagg
     6181 ttcctataaa ctcaatttga ggaaataatg ctaatagatt ctcttttaac atcaatgaag
     6241 aactaacacc attaggacaa atgattgctg ctttatagca tttttgaggc aaagtatctg
     6301 ctttctttaa ataacctccg aaatggataa caaaatatgc tgtttcacta tcaggtatgg
     6361 gattgtcaat agcgtccatc aagggcatca aagaatcttt gactaattca aataaatcag
     6421 gataatgttc tttaacatgc aatacatatt catttgaact aggtaggccg aactttaatc
     6481 tatagtaagc cggtataagg tggcggcgaa gattttctct caatccttcc ctttgtttaa
     6541 aatgtaacaa agaaatatct tccattctac ttataatagc ctctgttaat tgattaaagt
     6601 aaaccggagc aacatctact tcaccttcaa agcaacttga taataaaact gtgatatagc
     6661 gataatcatc ctcagaaaac accgtatcta taattcccaa atcaaccact gtatccaata
     6721 aaatagtggt tatatcttga ataacaggag atactaatgt ctctgaaaga catactcttt
     6781 caacatccct ttgataccta cacagaatga atactaaacc gaaaaggcaa acttttaatt
     6841 gattaacaat aggtactagc tgtagcttct cataataatc tttaactacc tgatttatca
     6901 aatcataagt taatgaatac ccccaactgg ataaaacata atccaaaccc caaatcccta
     6961 tggaggattc cagcaactca ctaaccattt gaaaagctaa gcggtgctta ttccactctg
     7021 aaccgtgtaa agtataacct tttgctctac tgtaccctag ctccaaatca ttatctaaca
     7081 taatctttct taatgattga atatcagata aggttgtatt cttacttact ttcaaaaagt
     7141 cttggtaatg attattcgat ataaaatcta atcggcaaaa agtgtaaaga tagattaaag
     7201 ctaagcgagt cgactttggt aaaaccaatt catccgactt aataatatct gtcaaagact
     7261 gcttcgtacg atttgataaa ctatagcgac cttgcttttt atccagcact atccctttat
     7321 tagctagata aggcactaaa taatctattc cttctttgac ttcctttata ggtaagctca
     7381 ccttaacaga taattcatat aatgatagct cacaatgatc catcaaagtc atcaaaataa
     7441 ctagtgctct ataatcaaac atttctcttc ctttctaact acaattatag tgtaaaagtt
     7501 ataagaataa aagagtattt gagcacaata taatctcacc ttttaaaaga aattattggg
     7561 ctgaaagttt ttagtgatta ttttcaactt tctattgact tttaaaaaca aagtgatatc
     7621 atttagatat caaataatgg gaggtcattc ttatgactga aaaactaatc aattcaaaac
     7681 caaatggtgt attcgcattg attctcattg agttgacaat cgtacttggt atctttatat
     7741 ttataatggg tgttggttcg gaaaacattt ttggaattat tatcggacct ttactaatcg
     7801 taattgcagg tctagctcat gctggtttaa aagttgtcaa acctcaggaa gctctggttc
     7861 tgacactctt tggtaattat acaggtacca tcaaagaacc tggtttttac tttgtcaatc
     7921 ccttcagcgt agcagtcaac cctgcaaacc acactcgact tggacaaagt ggtgatgtta
     7981 gcacaaaatc tcctttttta ggagctaaat catcaaatga caatgatgta aatcttgaaa
     8041 ttggcaagaa acacatttcc ctcaaagtca tgaccttgag caattctcgt caaaaaatca
     8101 atgattgctt aggaaaccct gtagaaatcg gtatcgcggt aacttggaga gttgtcgata
     8161 ccgctaaggc agtcttcaac gttgataact acaaagaata tctttcattg caatgtgata
     8221 gcgccctccg taatattgtc cgcatctatc cttacgatgt gtctcctaat gtggatacta
     8281 cgggtgacgg gcaagcagat gaaggtagtc tccgtggctc tagcgaaatt gttgctaacc
     8341 gtattcgtga ggaaattcaa agtcgcgtag aagatgctgg cttggaaatc cttgaagcac
     8401 gtatcactta cctagcttat gctccagaaa ttgctgccgt tatgcttcaa cgccaacaag
     8461 catctgccat tattgatgca cggaagatga ttgtagatgg tgctgtagga atggttgaaa
     8521 tggcactaga acggctcaat gaaggggaat tggtagaact tgacgaagaa cgaaaagctg
     8581 ccatggtttc aaatctcctt gtcgttcttt gtggcaatca tgatgcacaa ccaattgtca
     8641 acacaggaag tctttactaa agatggctga agctaaaaaa aagcagatcc cccttcgact
     8701 ctcaacaaag ttatacgctg cactcgcatc atgggcagaa gacgactttc gttcagtcaa
     8761 tgggcaaatc gaatatctcc tcacagagtg tgtcaagcaa cggaaaaaag acggaaaata
     8821 cgtatcagaa accattgacg aaccatttga gattgatatt taacaccttc tcctgtctgc
     8881 cgtgtcggat aggagaattt tttcatcttt ttttgtcaag taactttact ttacaaaaaa
     8941 aatgtgttat cctagtatgg ttgatgaaaa tcagtagatt gaatcgaata taaataccta
     9001 aaggagaaat caaaatggca gtacctgcac gtcgcacttc aaaagcgaag aaaaacaaac
     9061 gtcgtacaca ctacaaagta acagctccat ctgtaaactt tgacgaaact actggagatt
     9121 actcacgttc tcaccgtgta tcacttaaag gatactacaa aggacgtaaa atcgctaaag
     9181 ctgcatcagc tgaataatag aagggagata ccatgcgcgt aaatattaca cttgaacaca
     9241 aagaatctgg tgaacgcttg taccttactt ctaaaaacaa acgtaacact ccagaccgcc
     9301 ttcaattgaa gaaatactca ccaaaacttc gcaaacacgt tgtgtttaca gaagtgaagt
     9361 aagcattcaa tacgaatcaa tacagaagaa aaacgcttga tcagcgtttt ttctttttgt
     9421 taatttcact atattgcaag ggaaatcatt cgaatgacta cattattgat aatatttgtt
     9481 aagccatcaa aagtaattaa catttcatag cgagtaatcc tatttaaact cgtcccacta
     9541 tctatttctt cttatctctg tgttataatc ccgactttat cataagtttg tctaactgta
     9601 gcatttgaaa ccagataatt cttctgtttc acgcgaaaca ccctgcgcca agcaaggtgt
     9661 tcttgttttt atactcaatg aaaatcaaag agcaaactag gaagctagct gcaggctgct
     9721 caaaacactg ttttgaggtt gtagatggaa gctgacgtgg tttgaagaga ttttcgaaga
     9781 gtattaagtc gtataaatca tcgaagctgt cgcaatggta tgccactggt tagctgtagt
     9841 tgctgcgaaa tccttgtctg cgtagaagtc agtaaatggt aggatttcaa cttccagctc
     9901 gtcgatgcgg tcaagctggc cagccagata aacctcgata cggctttctg ctcgtttgat
     9961 gcgttgcaag agtccgccca tacggatgtc aactgtatcc aaaccaaaga ccttgttttc
    10021 tttcagccat tggtgactaa agagggcatg gaagtcttca atttggcttc taagttctgg
    10081 taattcttgt ctggcgattt gttgtaaact ttctttatca tccgcttggt aggcctgacg
    10141 aatgcgtcgt cccacatcta ctttgctact taaaatagca ttcaactggg cctgagtttc
    10201 aaagagataa gcatagtttc cagctttttc tttaatgtta gcaagcgtct cagcagcctg
    10261 agcgaagtgt ggcttgtcct gttcaggtgt catgtgtcgg tcaagtatcg gacagagaac
    10321 atcctgataa aagacatagc ggttgggatt gatgccactg agattacctg gtaggtctgg
    10381 taagaggttg gcaagatcaa tctgcataaa atcctcaacc gttagaccag tattggtctt
    10441 gaaatgcgca gacaaactat ctaggtcatt gcgatagctg agttctgccc agatttgcaa
    10501 gcttggtagg atagagaact gggcagtttc accaccattg tctccccaac ccgttacgat
    10561 gacttcttta atctgattgg cacggcaggc tttattagcc tcgatagcca ctagacggct
    10621 aaaatggttg tgaggtgtaa agccaatcca cttccaagct ccccctgcaa atgcaaggtc
    10681 atggctaatc ttgtgatgat tgcggaaatt acggttgtat ttttcctcgc tatcctgata
    10741 ataatcccag taaaccagag tcacacggtc tttgagacgg tctaggtaga cacgagtttc
    10801 ctctggaatt tccacatcac ggtcgtactg gccatccgct gacatgagtt tgaagaacat
    10861 atcactccac atctggcagt ggaaaccata tttgtcagca atatccagca cgcgctccaa
    10921 gtgttggcac atgaggagac tacgatccac aacaccgttc aaaatcaggt agcgtcccaa
    10981 accaaccaag tgggcttcgt ccatcccgat attgaccttg cgagtcttca gtttagacaa
    11041 cgtggcaaac atgccatcaa tcaggtcata aaccttttct tcgccaatga gaagaatgtc
    11101 ctctacatca cggagctcct gcacttcctt gacaccccat ttgacaaagg ccgacaagtg
    11161 ggccaaggtc tggatgcatg gtacaaaggt catgtcaaac tgttgggcat aggcttcgat
    11221 ttcctgcaac tcctctgctg aataagctcc acggaaatag ccaaagtaag gctgcccttc
    11281 aatctggtaa gtgtcttcca tgtaaagctc aaaggttgag tagcccatga gagccaagac
    11341 ctcaatcatc tgcttggcag aagccacatt cagcaccgca tttcgagaac agtcaaccat
    11401 gtaagccaaa tcttcgtaag ctgcttgttc ctcaatctct actttatcag cttctgctag
    11461 aactgttacc aacaaggata aggcacgata aagttggtga ggtttgcggt aggtcaattg
    11521 atagtgacct tcctcaccct cgatagagat agaggcttgg tcagactgag tgacagccac
    11581 ttccacatct ggtagagaaa tgtgaccttt taaaacctca atagcttgcg tttgtttggg
    11641 actaagtcct gtaaatctta ccattgcttt tcctcctgta gccagttgac aagagcaccg
    11701 tagagattgg catctgcgtg ataggtgcag gcctggataa ctggtgcgac cgtgtattct
    11761 tcgtaggtat cgacaaagtt atcaacagcc ttcttgacat cttggataaa atctggattt
    11821 tgactgatag agccacccag actgatgaca tctggatcga tgagatactg gatattgagc
    11881 aagccttgcg ccagattgcg gttcatgcgc tcaatggctt cttgacaaag agcattacca
    11941 gctgcggcct cttggtaaat cttgcgaccg tcccaatcag tatgaccaga tttttcaatc
    12001 acgtatcgta ccatattccc agttgatgct agttgcgacc agttattaag tttttcagca
    12061 ggggcaaggg ttgtcatgta gccaaattct ccacccagac cgtggcgacc tcgatgaagt
    12121 ctaccattga taatcatggc tccgccaatc cctgtcccaa tcacgacaca ggctgcattt
    12181 tcaagctctg gatgagctag tagttcactg agtccaacgc agttggcatc attttctaaa
    12241 tggacaggta gctgataaga gctaagcgcc tcataccaag aaaagccatg gatgtagggc
    12301 accgcactga agccatcaat cacacctgtc tcttgattga ccgcacctgg aacgctcata
    12361 gcaatcccac tgtaatcctg ttctgacaag cgttgatcta gccacgctag taaatcctcc
    12421 aagttttcag gcgttgaaat acttgtctta tacagtattt tcccatcagg agtcagactg
    12481 gcaaacttaa tcccagtccc tccgatatca atcgttgcaa tggtcattgt ttttaccata
    12541 aaaaggggcg aatcagcagt tagttcttac tttttcgccc ctcctttctt ttgatgttta
    12601 ctttttgaaa ttaaatttct tcttttttga tgaattctgt acgaatctct tgtggatcca
    12661 atggtcctga atgaactgga tatggtcgct caagtaagtc aagaatggtt tgttgatgtt
    12721 ctgatatgcg cacattttct tgactcatat tatagtaacg gaagacatag ccttcttcat
    12781 tttccgccac tttaaaggct gttggacaaa cttgcggtat gctgagaaca gaatggctca
    12841 agaggctacc agtcgcaacc acgcttcctt cctgtctagc aagctgaagg ctggtaaacg
    12901 gtgtctgcaa ggctttggca cgacggaaag ctgaaaagcg ttcttgggct tggtggcatt
    12961 caagtgcaaa ctcgacttca aactcacgca agcattgtgc ttctggcgtt gggaagtagc
    13021 cccagtcacc tagctcacct gatgcacgca aaatggtcac ggcaatggtg ttatccccaa
    13081 ggatttcgta ttcattcaat cccttattgg atacagtcac ccctttttca tcgtcataca
    13141 gactgacaaa agcttgttgg tgttgaggat tttcaggatt ttcccatgaa gcagctggtt
    13201 tgtttggtcg tgtcaccacc tcatagatac tttcagaatc attgcttgga cgcgtgttat
    13261 gagtcttgac caagagacgg atacggtgat ccttggcagt gttagtaaag cgagtcttga
    13321 agcggatttg tggattgtca acgaagacag tcaactcagt ttccagagga atgtttgtca
    13381 attcttctga ccgtccagcc tcacgcttca taaactcgat gataccttgt tgctcttctt
    13441 ctagcttttc atccgcactg acaggcacgg tcaattcatg tttgagcaag attttagcat
    13501 agcgatctgt gttttccaag acctcgtggc ccttaagctc tgcaaagatt ggctctgttc
    13561 cttttggttg gaaatagata tactcgtttc cgatgtcccc acggtcttcg aagcggataa
    13621 agtcttcata ggcttcgtga gttgtcttgt catatactgt gatgttgtca tccacactca
    13681 ccgttacgaa tggtgtatca atcactccgt tttggtaaat accctcacgg tgttcttgtt
    13741 ttccttccag caattggaag gttgtccaag aaagcggcgc taggtgaact ggaatggtca
    13801 cgcgcacttg tcgagcaata cgagcttggc ggaacttgtc ttttggtaaa tcgtactcaa
    13861 aattagctcc gaggtcttcg attgtagcct ctacaggatg accatccaag tcctccacac
    13921 ggtaacttgg caagataaga gcagccatct ttttgtagcc ttctgttggg tgcaattcct
    13981 tgaaatcaca agtcgccaca tcaatcactg tgctgacagt atcgacctta tcatgcaagc
    14041 ctgtgttaat gacagtaaag agatagtcac tttgagcctt atccgtagca attttaccct
    14101 tccactcgtt gagcaaatta cttttaacaa agtttcctac ttggttgacc ttggcaaaac
    14161 gcgtttccat ctcgcggtga acttcgtcca cgctacagcc acagatacta tcatgtggcg
    14221 cattctgcaa aagtgttttc caagcatagg tcaactggtc cttgtggttg tgtccaccag
    14281 tgataatagt caagggttct accacttgct ctaggaggtt gctattttct tggaaggctt
    14341 gttttaggta aatgcgggat gaagaagtgt tggcaagtgt gtaccagcca tctgtttcct
    14401 gactggtcaa ctcgcctgta acagttgata agtgttcagg aagcgcacct tctacagctt
    14461 gaacatattc atcaaaagaa ctatgaacaa agattacatc tgggaagagt tcatttgcca
    14521 cacgaatggc ttcgctcaga tttttctgta caggctggtg gtcacagccg ttcatcatca
    14581 accattggtt ggtcgaagcg taggcacgca catctgacaa tttttgtttc cagaaggtca
    14641 aggcctcatc tttgtcaact gggatttcat tcccattact gtaccagtta gcaaagagaa
    14701 tacctaaaac acgactacca tccacaccct gccagtacat ttctgaaaac tgggatgtaa
    14761 actgctcatc ttcaaggact tggttgtcaa atccaatcgg cttcacacca cgaccaaagg
    14821 ccgccacgtg aatgcctgat ttttgaagaa tttgaggcgc ttgtcccata tttccaaagg
    14881 tatctggaaa gtagccaatc tgggttgatt taccccattt ggcagcttct tgttgaccaa
    14941 tcaaggtatt gcggacattg gcttcactgg agatcaagta gtcatcctgc aagatgtaaa
    15001 agggaccaat tttaagtttg ccctcgtcaa tgtagcgttg gaccttgtcg cgattttcag
    15061 ggcgaatttg taagtagtca tcaaggacaa tagtttgtcc atccaagtgg aaactcttga
    15121 actcagggtc attttcaaag agatcaaaga gattgtcaaa caattccacc aactgcatac
    15181 gatggctttc aaaaggcaag taccactcac ggtcccagtg actatgtgag ataatatgta
    15241 caacaacatt ttccatgaag taaaacctca ttctaaattt aaattttaac gttttaaatg
    15301 taaacttgtg attctgataa gaatcggttg agctaaagcg agccccttag cgaatatcca
    15361 agtaatccaa gaccaactca cagaacatca tgttagccca ggagaaccat tcacgagagt
    15421 agagggtcgg atcatctaca tgaaagcttt cgtgcatgac acctgtacca ccatcgcagg
    15481 caaccagctg atccagcaag aattttttct ctgccttatc tcttgttgtc aatccttgga
    15541 tagaaagggc gattggccag atatagcgat agaaggtatg agaacttccg agaccgctag
    15601 cgtattctcc ttggtagaaa tatggatttt cagagctcaa aatggtacga cgagtagctt
    15661 gatacacttc atcatcgacc gaacagtagc ccagataggg cgcagctagt agacttggta
    15721 catttggatc atccatgatg ctggcatttc ctaggccatc cacttcaaaa gcgtaaatct
    15781 tttcgccctt gctgttggtg gtgtaagcgt agtttttgat tccttcttgg atttcatcct
    15841 gaagacgctt ggcatcagca ataacactct ggctatcagc taggtttaat gctgcgaaga
    15901 tttcttgcac ataacccaag actactacag caaacatatt tgacggaatc aagtaactat
    15961 actgacagca gtcatcgctc ggacgaaagg ctgaccaagt catacctgtc actgcaaagt
    16021 caggtccaaa gccatcattt accaaggtgt cttccttacg gtccgtgtct cggacaaaac
    16081 gataaggaga gttcttgtgg tcttgttcca ccgtccacag atggagaatt tccttagtcg
    16141 ctgcgacaaa aatctcatca aactgactag tctcgccagt ctctttccag aggagataag
    16201 ccaactgcaa aggatagcaa agcgaatcca cctcatactt gcgctcccag atccagccgt
    16261 taaggtctgt gtggtcagtc tcgtggtgcc ctttccagtt ctcctcaatg ttgaaggagt
    16321 tagcataggg atccttgagt accaaggtca tctgacgttt gaccaaacct gcaatggtct
    16381 gacgcaggag ggcatctctt ttagctacat gaaggtaggg tctgagttgg gctgtcgaat
    16441 ctcgaagcca catggcagga atatccccag tcaagacaaa agttgaacca tcttctaaga
    16501 tttcaaccgt attgtccaag gtatcggtgt agcaacgctc gaaaacatcc acccactctg
    16561 gatggtcctt agcccgctct gctacttcat ctatccattc tctaacaatt tctttcgaat
    16621 aaatcatcgt gcaattccct ctttcaaaca agtttcatgt tcagtatata gcttttgaga
    16681 cagaaaatac atacacaaat gatagtcatt tttctacaaa atagttattt ttgaaactcc
    16741 ttttctaaag gccctctttt tctgatataa tgtagaaaaa cagctaaagg aaagactatg
    16801 aaaccactac ttgaaaccat cgatacccgc tttggtactg ctagcaagca tgccttctct
    16861 cggggaaata ccctgccata cacaggcgtg ccttttggga tgaattactt tgtgccccag
    16921 accagtgacc agggtggatc ttggtttttt gatccgcatc tgcctatctt tcaggggatt
    16981 cgattaactc accagcccag tccttggatt ggggactact cttggctcct tctgacacct
    17041 gtcaccagtc aactgggggg agacagcctc tttcaccgcc agtcttctta tgatatagat
    17101 aaagcttgct tccagcctca ctatttgaag ctcttttctc tgcgttatca gattgaaacc
    17161 cagctcacac cgacttgcta tggtgcttct attcgtttga atcaaaagca aggcaaagcc
    17221 ctctccctct atcttcacgc agcagatgaa ctgacagtag agcaagtaga taagcggact
    17281 cttgccctgc gacaagaagg taaaactgaa actaacaaaa attcgctaac gatgttcact
    17341 gccctgcaaa tgaacacgga tattcttgct atcagccaag aagctggaga ctggcgaatt
    17401 gacttagcaa gtagtcaaac cgagatgcaa ctagccactt ctttcatctc tccttctcaa
    17461 gctctaatca atctacctca agaagatttt gatagctgta aaacaagtgc ccaagcggat
    17521 tgggaaaatc tcctccatcg ttttgacatt atagagacag gagaggctga ccgaaccttc
    17581 tttgaccact gtctctacag actcttcctc ttcccacaga ctttttatga ggttgatgag
    17641 tcagggaaag ccatccacat ggatctggct actggtactg tcaagcctgg tgtcctcttt
    17701 agcaacaatg gtttctggga taccttccgc accaccttcc ccctctttgc ccttatcata
    17761 ccggagcact atcaacgctt tttagaaggt ttcctcaata gctaccgcga tactggtttc
    17821 cttccaaaat ggctggctcc agatgaacgg ggtatgatgc caggtacact gctagatggc
    17881 attatcgcag atagcgcctg taaggacatg gcccccgacc tagaaggaga actcttccaa
    17941 gccatgctcg aaacagccag caaagccgac catctcggca tcaatggccg ccacggacta
    18001 gcccaatacc aagaactagg ttacctctct accgaccacc atgaaagtgt tagccatact
    18061 ctagactatg cctatagtga cttttgtatc gccagctgtg ccaaaaaact agagaacata
    18121 gaaatcgctg aaacctacaa ggctgcttca caaaattacc gccagctatt tgacgctgag
    18181 acaggttaca tgcgagcacg agacaatcaa ggaaactttc accctgactt ctctccttat
    18241 agttgggggc gagactacgc tgaatgctct gccattcaag ctactttagg cgttctccac
    18301 gacatccctg gcttaatcca actgatgggt ggaaaagaaa cctttagcaa ctatcttttg
    18361 aaagcctgtc aagatgctcc cctctttgaa acaacaggct atggttatga aattcacgaa
    18421 atgagcgaga tggctactgc tccttttgga caaatagcca tttccaacca gcctagtttc
    18481 cacatccctt atctcttccg ctacagcgat taccctgact acactgccct tcttatcaag
    18541 acgctccgtc agaaagcttt tcacccaagt tgggaagcct atcctggaga tgaagacaat
    18601 ggtagtctct ctgcttggta catctggtca gctctcggat tttatccaac ctgtccagga
    18661 aaaccaagct atgacctcgg aatccctctc tttgaccatc tacgagtcta cctagctaaa
    18721 gaagataaat ggctggatat ccatactaaa caaaaccaca accattttaa ctttgtcaaa
    18781 gaatgccgac tgaacaaaac actcgtatca actattcaac accaagacct cttaaaagct
    18841 gaacaactaa ctttcaccct cagctggcta ccaagtcact aataaccaaa agaacctttg
    18901 catcgcgcaa aggttcttct tttatgaaac ttggacttga agttgatcca caagctgacc
    18961 atccaccgtt aggttcagat agaaatccaa ggttttatct cctgcgaaat acagggttgg
    19021 tagatgcaaa tcttttttgc tttcccctgc ttggaattga aggacataaa tctcgtcctg
    19081 ataggcgaca ccatggacac ctgtccccgg ttgaatcgaa atcttagctt ctaaaggacc
    19141 actacattct ctgcgcttaa ctgtaaaata ggcattttct ccctttgcca cagctaggct
    19201 tttttctgca aatgctagtt cctgaacaac ttcttttttt gataatccag gagttttata
    19261 aagggaaatc ttggtcaata caggaataga ttgtgcctcg gtaatcatca cgcgcacctt
    19321 ttgtgcctct actagcgaac ctcgcaagag gcgcttatga ccaactgtga agcccctgcc
    19381 aaattcctgc cagacaccat ccacctctac ttgcacatgg aaagcagaaa tacgttggcc
    19441 taacttcaaa tcttctctca actcaattac atcaaaagtt ttaggagaac ctaagtcgag
    19501 ttctaactgg atgggcaagt ctgcatcgtt tgcccaagag ctggtctcaa ggccgtctgt
    19561 caaatggcga caagcaaagt ctgcggaaag agctggacca gatacctcag ctcccagagc
    19621 caaatcttct ttatagagct cattgcgata ggtcgcaaat tcataaagtc gttcaatatc
    19681 ctttgcatca aagagcccag cttgattcgg cggaatatta agcaagagtg gagttcctcg
    19741 ccctactgag tgaaagtaga tttcgaccaa ctcctcgaga gacttaggat cctgatcctc
    19801 atggtagaac cagcctggac ggatggaaac atctgcctct ccgattgaaa aaatcgtgcc
    19861 cgagggatcc ccgtgctgaa gatagttcag ctctgcttct gttcctagtt tatcaggatt
    19921 caccttttgc cacagtggat cacctgcata ccctcgttca ttgccaatcc agcggatact
    19981 ggtgccttct gttgaaaaaa tcaagcaatc gccctgcagg tcacgaatgg tttcaaacca
    20041 tttttcaaat tcataattaa ccttttgcgc gccctctcct ctggcaccat ccatccaaac
    20101 ctcagcgaac ttaccagcat tcccatagtt aggatttgat aagatttcct tcaactgagc
    20161 cagataatag gcattgtagt ccgcttctcg gtccacatga tagaggggac tatgggcatc
    20221 ccacggtgac aggtagaccc ccatatccat atcaaactct gtggcagctt gggatacttc
    20281 aaggagcaag tcgccctttc ctctcctcca aggactgacc ttaaccgaat aatctgtgtg
    20341 agctgtcgga taaaggacaa agccatcgtg gtgcttgacc accaaaatca actttttgaa
    20401 gcccgtttcc ttgagcacac gaacccactc acgcgcatcc aactgactcg ggttaaagcg
    20461 ctcaggatcc tcctgtccag tcccccattc ttggtcataa aaggtattag gaccgaagtg
    20521 gataaaagct gctagttcat ctcccagata agctagctga gtctgacttg gtaacggtcc
    20581 atgcggtttg attttcttca tcgttatata tctccttctt tagcaacttc tcttgttcac
    20641 aaggttatcc acaggttgtg gataataaac catgatctaa cagccagctc tttccaactc
    20701 caactggtag gctcaggatt ttgctcctca atattccctc ttcaaacagc tctgtcatat
    20761 ggttctgcta acacctctca gaatgctact ctccataatt attctcaggc ttctttcagg
    20821 tcattgtgtg aagaccattc actctccaga cttttccaca gattgtgaat aagtgattat
    20881 tctaaactat cacctcgtcg actataacaa aaaataaaaa gagggtcaat aagataatta
    20941 tctcttccta aatactcaga aaagattcta taatttgtac aattgaacaa gaaatgcttc
    21001 tccaaaatct atcttcaaaa gaatgttgca tctttttatc ctttcacaca aacatttctc
    21061 tttatacaga tccaagtgat aaccagatga taattggaca ctttttggtt atttgtgtat
    21121 tttttgaaaa attttttaaa aaaattttat atcctcttta atagaagttt atgaatttgt
    21181 atatatgtat tccatcctat gttatgtata ataacataaa attgtgctaa atatcataat
    21241 ttatattatt ttccgagaaa ttatagccat tgacattacc taggaattgc gttataacat
    21301 acatgtaagc ggtacccaaa atggtgccaa gtcaaaattt ttaaggagga aaatacatgt
    21361 cttcacatcc aattcaggtc ttctcagaaa ttgggaaact gaaaaaagtt atgttgcacc
    21421 gtccaggcaa ggagttagaa aacttgttgc cggactatct tgaaaggctt ctttttgatg
    21481 atattccttt cttggaagat gctcaaaaag aacatgatgc atttgcccaa gctcttcgcg
    21541 atgaaggaat tgaggttctc tacctagaac aactcgctgc tgaatcattg acctctccag
    21601 aaatccgcga tcaatttatc gaggaatact tagacgaagc caacatccgt gatcgtcaaa
    21661 ctaaggttgc tattcgtgaa ttgcttcacg gcatcaagga caaccaagaa ttggttgaaa
    21721 aaacaatggc tgggattcaa aaagttgaat tgccagaaat tcctgacgaa gctaaagatc
    21781 taactgactt agttgaatca gagtatccat ttgcaattga cccgatgcca aacctctatt
    21841 tcactcgcga cccatttgca acaattggaa acgccgtatc gcttaaccac atgtttgcag
    21901 acactcgtaa ccgtgaaaca ctctacggta agtatatctt caaataccac ccaatctatg
    21961 gcggaaaagt ggatttggtc tacaaccgtg aagaagatac gcgtatcgaa ggtggagacg
    22021 agctagttct ttctaaagac gtccttgcag taggtatctc tcaacgtaca gacgcagctt
    22081 ctatcgaaaa acttttggtc aacatcttca agaaaaatgt tggcttcaag aaagttttgg
    22141 cctttgaatt tgctaacaac cgtaaattca tgcacttgga tactgtcttc actatggtag
    22201 actatgacaa gttcactatt cacccagaaa tcgaaggcga ccttcacgtt tactcagtta
    22261 cttacgaaaa cgaaaaactt aaaattgttg aagagaaagg tgacttagct gaacttcttg
    22321 ctcaaaacct tggtgtagaa aaagttcatt tgattcgttg cggtggtggc aatatcgtag
    22381 cagctgcgcg tgaacaatgg aacgacggtt ctaacacttt gaccatcgca cctggtgtgg
    22441 tagttgttta tgaccgcaat accgtgacca ataagatttt ggaagaatac gggcttcgct
    22501 tgattaagat tcgcggaagt gaattggttc ggggccgtgg tggacctcgt tgtatgtcta
    22561 tgccatttga acgtgaagaa gtgtaatcgc tgttcggtat tcgtcaatag aaaatgtaaa
    22621 aaatagaaag aggaaataat aaaatgacaa attcagtatt ccaaggacgc agcttcttag
    22681 cagaaaaaga ctttacccgt gcagagttag aataccttat tggtctttca gctcacttga
    22741 aagatttgaa aaaacgcaat attcaacacc actaccttgc tggcaagaat atcgctctcc
    22801 tatttgaaaa aacatctact cgtactcgtg cagcctttac aactgcggct atcgaccttg
    22861 gtgctcaccc agaatacctc ggagcaaatg atattcagtt gggtaaaaaa gaatctactg
    22921 aagatactgc taaagtattg ggacgtatgt ttgacgggat tgaattccgc ggattcagcc
    22981 aacgtatggt tgaagaattg gcagaattct caggcgttcc agtatggaac ggtctaactg
    23041 acgaatggca cccaactcaa atgctcgctg actacttgac tgttcaagaa aacttcggtc
    23101 gcttggaagg cttgacattg gtatactgtg gtgatggacg taacaacgtt gccaacagct
    23161 tgctcgtaac aggtgctatc cttggtgtca atgttcacat cttctcacca aaagaactct
    23221 tcccagaaaa agaaatcgtt gaattggcag aaggatttgc taaagaaagt ggcgcacatg
    23281 ttctcatcac tgaagatgct gatgaagcag ttaaagatgc agacgttctt tacacagacg
    23341 tttgggtatc aatgggtgaa gaagacaaat tcgcagaacg tgtagctctt cttaaacctt
    23401 accaagtcaa tatggactta gttaaaaaag caggcaatga aaacttgatc ttcctacact
    23461 gcttgccagc attccacgat actcacactg tttatggtaa agacgttgct gaaaaatttg
    23521 gtgtagaaga aatggaagta acagacgaag tcttccgcag caagtacgct cgccacttcg
    23581 atcaagcaga aaaccgtatg cacactatca aagctgttat ggctgctaca cttggtaacc
    23641 tttatattcc taaagtataa ttttagataa taaaccgtct accaacagct atgagggctg
    23701 cgactaatag ctttagtccg gtcctctttt atataatggt aatctattat ttcttataaa
    23761 atatgtgaaa aatcattaaa ttgaaatcta aacgcattct attgagtgtg ataaaggaga
    23821 atttatggca aatcgtaaaa ttgtagtagc tttgggagga aatgcgattc tttcttctga
    23881 cccatcagca aaggctcaac aagaagcttt agttgaaaca gctaagcatc ttgtaaaatt
    23941 gattaaaaat ggagatgatt tgattatcac tcacggtaat ggacctcaag ttgggaatct
    24001 cttgctccaa catttggcat cagactctga aaagaaccct gccttcccac tcgactcact
    24061 tgtcgctatg acagaaggta gcatcggttt ctggttgaaa aatgctttgc aaaatgctct
    24121 cttggatgaa ggcatcgaaa aaaatgttgc ctctgttgta acgcaagttg tcgtagataa
    24181 aaatgatcca gcttttgtta acttgagtaa accaatcggt cctttctatt cagaagaaga
    24241 agcaaaagca gaagccgaaa agagcggagc gactttcaag gaagatgctg gccgtggctg
    24301 gcgtaaggtc gttgcctcac caaaacctgt tgacatcaaa gaaattgaaa ccatccgtac
    24361 tcttttaaat agtggtcaag tcgtcgtagc tgcaggtggt ggcggtattc ccgtcgtcaa
    24421 agaaaacaat ggacatttga ctggtgtcga agcggttatt gataaagact tcgcttccca
    24481 acgtttggca gaattggttg atgcagacct cttcatcgtt ttgacaggtg tagattatgt
    24541 atttgttaac tacaacaagc caaaccagga aaaattggaa catgtgaatg ttgcccagct
    24601 ggaagaatat atcaaacaag atcagtttgc accaggtagc atgcttccaa aagtagaagc
    24661 agctatcgct tttgtcaatg gtcgtccaga aggaaaagca gttattactt cccttgaaaa
    24721 tctaggcgcc ttgattgaat ctgaaagtgg aacaattatt gaaaaaggat aagttgtttt
    24781 actaataaga tgtattctat ttctagtatc tttatatcaa attagaaatt attcttgaaa
    24841 acatgtacaa tatttcaaaa gatattagtt ttttagactt taatatggta aaacaaatat
    24901 aaatagaaag cgttttctta aatgtttatt taagaaagta gttggttttt tacactttgt
    24961 tagacatcag gaggaaaaac aaatgagtga aaaagctaaa aaagggttta agatgccttc
    25021 atcttacacc gtattattga taatcattgc tattatggca gtactaactt ggtttatccc
    25081 tgcgggggcc tttatagaag gtatttacga gactcagcct caaaatccac aagggatttg
    25141 ggatgtcctc atggcaccga ttcgggctat gctaggtact catccagagg aaggttcgct
    25201 cattaaagaa acgagcgcag cgattgatgt agccttcttc atccttatgg ttggtggttt
    25261 ccttggcatt gtcaacaaaa ctggtgctct tgacgtaggg attgcctcta tcgtgaagaa
    25321 gtataagggc cgcgaaaaaa tgttaatttt ggtactaatg cctttgtttg ccctcggtgg
    25381 tacaacttat ggtatgggtg aagaaacaat ggccttctat ccactccttg tgccagttat
    25441 gatggccgtt ggttttgata gcctgactgg tgttgcaatt attttgctcg gttctcaaat
    25501 cggctgtttg gcatctactc tgaatccatt tgcgacaggt attgcttcag cgactgcggg
    25561 agttggtaca ggggacggta tcgtacttcg tctgatcttc tgggttacct tgactgctct
    25621 tagtacttgg tttgtttacc gttatgcgga taagattcaa aaagatccga ctaagtcact
    25681 ggtttatagt actcgcaaag aagatttgaa acactttaac gtagaagaat cttcatctgt
    25741 agaatctaca cttagcagca aacaaaaatc agttctcttc ttatttgtgt tgacattcat
    25801 cttgatggta ttgagcttca ttccatggac agaccttggc gttaccattt ttgatgactt
    25861 taatgcttgg ttgactggtc ttccagttat tggtaatatt gtcggttcat ctacttctgc
    25921 actaggtact tggtacttcc cagaaggcgc catgctcttt gcctttatgg gtatcctgat
    25981 tggtgttatt tatggtctta aagaagataa gattatctct tccttcatga atggtgctgc
    26041 tgacttgctc agtgttgcct tgatcgtagc gattgctcgt ggtattcaag ttatcatgaa
    26101 cgacggtatg attaccgata caatcctcaa ctggggtaaa gaaggcttga gcggtctatc
    26161 ttcacaagtc tttatcgttg taacttatat cttctatcta cctatgtcat tcttgatccc
    26221 atcttcatct ggtcttgcca gcgcaactat gggtatcatg gctccacttg gagaatttgt
    26281 aaatgtccgt cctagcttga ttatcactgc ttaccaatct gcttcaggtg tcttgaactt
    26341 gattgcacca acatctggta ttgtgatggg agctcttgca cttggacgta tcaacattgg
    26401 tacttggtgg aaattcatgg gcaaactcgt agtcgctatt attgtagtga ccatcgccct
    26461 tcttctcctt ggaaccttcc ttccattcct ataaaatagt gagtgaggtg attccatgaa
    26521 aatagatata acaaatcaag ttaaagatga atttcttata tcattaaaaa ccttgatttc
    26581 ctatccttca gtactcaatg aaggagaaaa tggaacacct tttggacaag caatccaaga
    26641 tgtcctagaa aaaactttag agatttgtcg agacataggt ttcactacct atcttgaccc
    26701 taaaggttat tacggatatg cagaaatcgg tcagggagca gagcttctgg ccattctctg
    26761 tcatttggat gttgttccat caggtgatga agcagattgg cagacaccgc catttgaagc
    26821 aactatcaaa gacggctggg tattcggacg tggtgtccaa gatgataaag gcccttcgct
    26881 cgcagctctc tatgcagtaa aaagcttgct ggaccaaggt attcagttca aaaagcgcgt
    26941 acgctttatc tttggtaccg atgaggaaac cctctggcgc tgcatggcac gctacaatac
    27001 catcgaagaa caggccaaca tgggctttgc acctgactca tcttttcctc tgacctatgc
    27061 tgaaaaaggg cttctacagg tcaaacttca tggccctgga tcggatcaac tagagcttga
    27121 agtaggaggc gcctttaacg ttgtaccaga caaggccaac taccaaggtc ccctctatga
    27181 acaggtttgt aacggtctca aagaaactgg ttatgattac caatccactg aacaaaccgt
    27241 aacggttctc ggagtgccaa agcatgctaa ggatgctagt caaggtatca atgctgtcat
    27301 ccgactagct accattcttg ctcctctcca agaacaccct gctctcagtt ttcttgcaac
    27361 acaagcaggt caagacggca caggaagaca aatctttggt gatatagcag atgaaccttc
    27421 tggtcaccta tcctttaatg tcgcaggtct catgatcaat catgaacgtt ctgaaatctg
    27481 tattgacatt cggactcctg tcttagctga taaggaagaa ctagtagagt tgcttacaag
    27541 atgtgcacaa aactaccaac tccgctacga agagtttgac tatctagcgc ctctatacgt
    27601 cgcaaaagac agtaaactcg ttagcacact gatgcaaatc taccaagaaa agactggcga
    27661 taacagtcct gctatttcat ccggtggtgc cacttttgct cgcaccatgc caaattgtgt
    27721 agccttcggc gccttattcc caggagcgaa gcagacagaa catcaggcaa atgaatgtgc
    27781 cgttctagaa gatttgtacc gtgctatgga tatttatgcc gaagccgtct atcgacttgc
    27841 aacttaatca ggcaactgtt tctaccaaaa aaaatcgacc gattaatgaa ctgcacccca
    27901 aaagttagac agaataaatc taacttttgg ggtgttttat tatgaaattg agttatgaag
    27961 ataaagttca gatctatgaa ctaagaaagc aaggacaaag cttcaaacag ctttcaaaaa
    28021 gatttgtgtg gatgtttctg gtctaaagtc atctgaatct ttgagatgag ctttataaat
    28081 cgcttttttc agtttttgca ctggtgtttc gataaactca aactttttag ccgtggtatt
    28141 gcctgatttt atagtatatt gaaactagaa tagtacacct ctacttctaa aacattttta
    28201 gaaatcgatt tgactgtcct gatcgatttg tcctgttctt atttcatttt actatatttg
    28261 agccacttcg tctttaacgg ctttattcat aagctcttgt aatttttctt tactatcaat
    28321 tacttctgat tttccgttgt aatttattgt aataggtttt aacttaccta atttctcgac
    28381 acgctcagaa atttgatctt ttttgaaggc tgcatatgtt tttcctaaga ttttttcgaa
    28441 aatatattta tcagatagcg gtttgccttc ttcttcagct tggtttttgt attgatttga
    28501 aacataagga acaaatcctt catagtaacc taatgctccc ataagttcaa aagcttgttt
    28561 tctaattcaa accattgcaa ctcagatttc agcttttcag ataaatcctg ctcatccaaa
    28621 taatgacttg aaattagtgc tgaactcgtt tctgtatcct gtacaggctg agcacccata
    28681 ccagcaaaaa aataaactcg ttcctagcaa gaccgaacaa gctcctattg catatttcct
    28741 caaagaaaaa cgctgctttc tctcaaattg aaattctttc atcccatctc ccatcattca
    28801 ttattactgt atattttgta tatcagaaat agtttgtatt cacaaatctt tctagttatt
    28861 cccttatcat tcctaattaa gggagataac atacaataat ttttagttaa atgtatatcg
    28921 atgttttttg tttttcttaa taaacgcaat acaaaaagag cctgttgcca agctctttat
    28981 actcaatgaa aatcaaagag caaactagga aactagccac aggttgctca aaacaccgtt
    29041 ttgaggtagt agataagact gacgaagtca gctcaaaaca ctgttttgag gttgcagata
    29101 gaactgacga agtcagtaac atctatacgg caagacgacg ctgacgtagt ttgaagagat
    29161 tttcgaagag tattagtcta ttatttcttc tcagcgcgaa gggctgacaa gatttgtgta
    29221 cggatatcat ccacaccatt tggagtattt ggtaaaaaga tggtttgatt tcctttagag
    29281 gcaaaggtat tcaaggtatc caaatactgg ttggtcaaga ggatagacat gatttgttct
    29341 tctgtcatgc caacattggc ttccttgagt tcggtgatag actctgccaa tccatccaca
    29401 atcgccttac gttgttgggc aatccccaca ccatgaaggc ggtctttttc tgcttcggct
    29461 tcagctgcag tgacaatttt aatcttgtca gcttccgcca attcttgtgc tgcgacccgc
    29521 ttacgttgcg ccgcattgat ttcattcata gattgcttaa cttctgcatc tggttcgacc
    29581 ttggtaatca aggttttcac gataatgtag ccgtaagtgg tcatttcttc tgctacttgg
    29641 tgttgaacct caagggcaat ctcatctttt ttctcaaaca attcatccaa ggttaatttt
    29701 ggaacagaag agcgaagagc atcttcgata taagatttaa tctgagattc tggacgtatg
    29761 agtttatagt aagcatctgt cacgctctgc tcgttgacac ggtactgagt cgctacattc
    29821 atcataacga acacattgtc cttggtctta gtctcaacca caatatcact ttgcaacaag
    29881 cgcaactgaa tccgtgctgc aatcgagtca atcccaaaag gcaagcgaat atgaataccg
    29941 ctattagcaa ccttttggta ttccccaaag cgttcaataa tcgccaccga ctgctgacga
    30001 accacataaa ctgtactcag tgtgactatc accaatagga gcacacaaac aatcagaaaa
    30061 atcatgaaaa atattgccat aatggaacct ccacaagtat ttttctagta ttatagcaca
    30121 tttaaagaag gctgtgccgt ttttactgcg atttttcctg aaatgtcaat aattagaggt
    30181 gaattgtcct attgtcgtct aatctcttgc taaaataact ctttataaaa ggcaatcgtt
    30241 tcttctaagg ttggcataaa tggatttcct ggtgcgcagg catcaatcaa ggcattctta
    30301 gaaaggtatt caaagtcgaa atctttttct tcaataccaa gttcagtcaa tttcttagga
    30361 atacctactg tctcagaaag cttctcaatc tcagcaatcg cataatcggc acactcttga
    30421 tctgatttac cttccacatg aaggcccaag gctttggcaa cattgcggaa agcttctggt
    30481 acacgtttag cattttcacg ttctataact ggtagcaaca tggcacagca aacaccatgt
    30541 ggcaaattat atactgcacc gagttggtga gccattgagt gaacataacc aagaccagca
    30601 ttattaaagc tcataccacc aaggaagatg gcattgacca taccttcacg cgcttcaata
    30661 tcatgtccat tttctacagc acgaggaaga tattccttga taagctcaat agcaccaata
    30721 gacagtttct tggttacatc ataagcacca ggtgttacca aagcttcaac agcgtgagtc
    30781 agagcatcca taccagtagc agcagtcaga cctttaggtt tggaaagcat gagttccggg
    30841 tcattaacag agataagagc aaggctattc ttgtcaacca ttaccatctt aaccttgcgt
    30901 tcttcatcag taatcacata gttaatagtg atttctgcag aagttcctgc cgttgtattg
    30961 atagccacaa ctggcaagcc ttttttagca gacttatgaa gcccttcata atcctgtggt
    31021 tttccaccat ttgtagccat gatagaaata caactagctg catcctgtgg agaacccccg
    31081 ccaagactga tgataaaatc acatccatgt tcttgcaaag cagctacccc atctgtgaca
    31141 ttcttacaag tagggtttgg ctctacatcg ctaaagatga catattcgat tccttctgta
    31201 tccagtggtt ttaaagtctt aggtaaaata tcactgcctt cgatgtactt atctgtcacc
    31261 aaaagtgcct ttttatagcc aagttccttg atataaggac ccacttcatt tacaacacct
    31321 tttccaataa ggttgactgc cggaacataa aatgtagcca tataattttc ctcctgcgcc
    31381 tccgcgctat ctatttaaca tcattatatt actttttgta ttcgttttca attatttgtg
    31441 aattgtttaa caaatctttt taaaaggata ggagggacgt aagttcacct cctatataaa
    31501 caagttttat ttatgtagtg gtcccaacaa ctgacatgca cgatagtctg ctgattctag
    31561 atcttctgtt ccaaataagg accaattttt aggtctaaag atatcttcct caggtacatt
    31621 atgcatattg acaggaattc tcaacataga agccaaggta atcaagtctg ctccaatgtg
    31681 tccatatgtt atggctccgt gattagctcc ccaattattc atgacgtcat agacagactt
    31741 gaaagcacct tttcctgtca aacgtggagc aaaccaagta gttggccatc ctggatctgt
    31801 acgattatct aaagtatggt gaacatcttc aggaagttca agtgtataac cttctgcaat
    31861 ttgtagcact ggaccaaccc cttttagaag attgagacgt accattgtta ctggcatatc
    31921 ccccttcgtc aagaaacgag ttgagaatcc tcctccacgg aagtattcgc ggtttgctgg
    31981 tgggaagtct gtattttcaa gcatagcctg cacttcactt tcatccaact cccagaatgg
    32041 tttcataaca ggtttgccat ctcgagtagc ttgacctgta ccatctaatg tacaagaacc
    32101 agagttgatt agatgtaaga agccagctgc agcacgaccc tctaaagtat atcctgttac
    32161 acgttcaaca gcctctggac tccaataagt acgcacatca gcaaagattt gtggagtatt
    32221 tgttaataga taattaaaga gcatagacac accatttagt gaatcattct ctgtcgcaaa
    32281 tacaaatggt tttcgaatac cattccagtc aaactgagta ttgaggaaag tttccataaa
    32341 atctccattt ggaaaatggt ctgtccactg acgttgacct tggaaaccag ctactaaagc
    32401 atggtgacca actgcttctt cctcaaaacc aagttcagca agtcttgggt taccaaccat
    32461 taagtcacgt ccaatcatga acatcttaat aacaaattcc cattgtctat ctttttcttc
    32521 acggcttaaa acaaggtctt cacggttatg gtcgaatcct tcttttacgt tttctttcac
    32581 ccatttgagc gcacgttcga actcttcagg gtcgtaaata ccacggtcca tacggcgtgt
    32641 gaactccgtc atatctaccg attcatttcg cattcctaag tattcttgga agaaatccgg
    32701 atttacaata gaaccaccaa tccccatcga aacactaccc attgataggt aagcagtgtc
    32761 tctcatcaag ccagttgcaa gagctgcccg cgcataacgt aaaagttttt ctttgacatc
    32821 ttctggaata gctgtatcat tagcttcctg aacatctcta ccataaatcc caaaggctgg
    32881 aatccctttt tgagtatgtg aagctagtac agctgcaaga tagacagctc ctgggcgttc
    32941 tgtcccatta aatccccaaa tagcatgagg aatatctgga gacatatcca tagtttcact
    33001 accataacac cagcatggtg taactgtaat tgttgcgcaa acatttgatt ttttgaacaa
    33061 ctcatgggaa gctgcagcct ctggtacacg gccaatagta gatggagaaa tcacgcattc
    33121 cacaggttcc ccatctggat atttcaatgt gcttgaaatc aaatctgcca cacttttagc
    33181 catgttcatt gtttgtactt caagtgattc gcgtacacct tgacgacgac catcaatagt
    33241 cggacgaatc ccaatacgtg gatgttgaat catactattt tcctcttatt tttctgtttc
    33301 tttcatacta ccgatgataa tttttaaaat tacttataag tataaacctc tacctctgcc
    33361 aaacttaaag gaattcctgc gtttctcaaa gaaattctaa ccttttttcc cttcagccct
    33421 tttaagtcta tggatagatt attgctttct aaactgtcaa tatgttgttt aaaaacttca
    33481 tgattatttg aatcatatat aataatatca aaatttgata atctctgaat ttcagcatct
    33541 gttctattat aaataattaa cttttctaat tcttcggttt gtgctaaatc tatctcccac
    33601 catgaaggag aatctccttt ggtatgagtc actgaatgat gaccataatc tccgttttta
    33661 tttccatcaa ctgctagacg agaaaaacca ttgtaatccg ttgaactctg tcgagtttct
    33721 ttggttaatg caatattaga aagtttcttc ggagttctct ttgaaccata gacttcaact
    33781 tccgctaaac ttaacggaat agctgctgat tttaattcta ttttgactag cttagcccct
    33841 acagaaggta cttttaaaga taacaaacca tcaactactt tatcaaaatg tcttctaaaa
    33901 acttcttctc ctgatgaaga tagaaaaata acatcaaaat tagataaacg ctgaggttcg
    33961 gcatctgttc tattataaat atcaacttta gaaaccgtaa actcttctcc cagatcgacc
    34021 tgccaccaag cgttagaatc tgccttagta tgagtcaccg aatgatgtcc gtaatctcca
    34081 tctttattac catcaactgc taaagcagct acaccctcat aattggttga actttgagta
    34141 gctaccttat ttgtagagac tactttatct tctgttattt tatctatatc ctcttcagat
    34201 tgcttaccat ctgattctct aaaaacctct acttctgcta aactcaaagg cactccactc
    34261 gttagtaatt taactttaat ataccttgct cctttttctt tgaaatctag actaacagat
    34321 tcacccgaca aattattaac atgtttctta gcaacttcgt ttctattatt gtcatataga
    34381 atcacatcaa aattagatag acgttgagtc tcagcatctg tgcgattata aattttaaca
    34441 agcccaactt tatccatttt tttcaaatcg acttcccacc aagagggatt atctgcccta
    34501 gtgtgtgtta ccgaaccaga gttaaaatta ccatttctgt taccatccac agctctatta
    34561 gggtctccat tgtaatctac agaactttgt gttgttggtt ttgcatatgc tatattcaaa
    34621 ttaccatcat taaatttatc tggtgttggg aaagggactg ggcctgtccc ttcagtattt
    34681 atagacatct ctaccattcc attatgatta accgtaatgg tataaacatg ggtattctca
    34741 tcccaatttt ctgtataagt ataatgattt ttatcgccac ttatatttat ctgaggttta
    34801 tgaccagtat gcccttttaa tgtaagtgtt gttgtcctaa agtcattatc tacaggattg
    34861 atggaataat ttttgcttat ccagttcgct aactctaatt cttctttctt ccaacttttt
    34921 gatgcatcaa aatttcctga taatgcccac atagctgtct tatctgtcct gtaattgttc
    34981 aataaaatat gtaaattatt tggattttct ttaacaacag cgtaagtatg tggcgtcaaa
    35041 tctaacgata acgactttgt attattagta tacataggca acattacttg ctgattttta
    35101 ttgatattag cattactatt ataaatatac caggaattac ctacacgctg agcataccca
    35161 tctccttcat aaagttttgg ataaagcgag tttaaatagt tgactttact agacaattcc
    35221 tcactatttt tagtcaaaat ttttgcatta gggaatatag atgaaatctt ttccttatca
    35281 attttctcat gtattacagg aagaatatga tatctcccat tattatataa aggcattgtt
    35341 tcatcattcg aataaagtcc ttgataaaat ccgtttaatg aactaatcct accttctcca
    35401 ttccaaaata cagcttttgt tctatttaca acttcttcct tacttggagc tggattttgt
    35461 atagcatgtc taaagaaagg aataatacct ttagtaaatg ctggagttgg tacatcattt
    35521 gtcataaatg tatacgcggc acattcaaaa ttataaactg tgcctccccc agtatataca
    35581 ttcatcattt ccatagcaat cattgattct ggttccgatg cataggatct catatcccta
    35641 gctcttccag tttcaaatgt gtttgtataa tgtttttccc accatttcca tgtatctgtt
    35701 gatgagcccc agttatcaca taagccactc aaccaaaatc cactaacgat agaatctgta
    35761 cccgcatcat ctcttattgg cgtattttta gttgccaaca ccaaattttt atgatatttt
    35821 tgactcgctt caaagaatgt cggatcattc ataatagttt cccagaacca tttttcatga
    35881 tcatgccaga taaaatgcgc tccatatttg gcacaaactt ccaaatattt agcactatgc
    35941 ggagctaact ggttattgta aatccaataa ttctcaatat ttaaaacacc ttttaacaca
    36001 ctatactttt ggaattgttc atctaaccac tctggaggaa ctgtattacg ctctccagcc
    36061 gacataataa ccaagaaaac tggaatgttt agactttgag cttcctccaa catcttgaca
    36121 taccattctc tcaattcttt cgtatctcgt ggaatacaac ttgttggttt acagactttt
    36181 gcaggatgaa gttcaatcgc tgcatatggt tttacatctt caggaatagc ttcccatgct
    36241 cccttcaatg tgttccccca ccataatccg ttaccattat cattgccata caacggagaa
    36301 agcaacaatg gcgattcatt attaatcgtc gttctcattt gaacacgatt atcagcctta
    36361 actcctgcta acaatccaaa acataacatc ccaatacata caaacagtat tgtgattaat
    36421 tttcttttta ttttttcttt attcatgact tatacctaaa aatttaactc aataattttt
    36481 tctgaattaa ataccaattc aatattttgt acatcagtat ttttgccata tattcttact
    36541 cttacttttt gatctttgtt tcctccttcc aattttagga atgttatatc cccatttttc
    36601 caagcaaacg ataccttata tcctcctctt actctgaaac ctttcacttc tccttctgac
    36661 caagcagaag gtaaagctgg aattagtgat aaccaattat gatggctctg tactaataat
    36721 tcacaaattc cactcaccaa acctaaatta ccatcaattt gaaatggtgg atggtcaaga
    36781 aataaattgc caagagtcgc attatttaac aaaccattaa tctggttata agcaggttca
    36841 ccttgatata gtctcgcaaa aaaatgaatc agccatgcag cactccaacc tgtttgtgta
    36901 ctagcatgca aaccacttac taaccaatta ttaatcgctt gctccctctc ctgtgaagat
    36961 aaaaagttag cgtttgataa tctcctattg atagtgattt tagctgcttc tgctaattcc
    37021 ggagttttat gaatatcaat ctcattataa ggataaagcc caaatagagg tgaaatgtgt
    37081 ctatgcccag gctctacttc ttcataatct tctaaccatt cttggatttg cccattacta
    37141 cctatttttg ttttaggtag tttctttttt aactccttca cacgactaat aaaatccgaa
    37201 ttgtctccta attgttttgc aattccaatg catgaatcac aaaaatatct taaaatttga
    37261 ttatcaattg tagatgatag acaagcattt ccttcaatac cattttttaa gcgatattta
    37321 ttttccggtg agacacttgg acctgtcatc aagtagccat ccacctcaaa taaataatct
    37381 tcaaagaaaa gaaatgcttc ttttatcatt tcaaaatgtt ccgtaagaat acgctcatct
    37441 tggaaatata aatagtgttc ccaaatatga gtacataacc atggaatagt taatacccaa
    37501 attgcagccc ccatggcatg agattgggga gccgtatcgc caaaaccatc cgtattatga
    37561 tgtgctgtaa aacctctagc tccatacatt ttcttagcgg ttagtcttcc cggttctctc
    37621 attctttcga gcatatcaaa taatggatat tctacttctg gtaaatcaca tggacctacc
    37681 atccaataat tcatttgagt attaatatta atcgtatatt tagaacccca aattggattt
    37741 aattcatcac accatattcc ttgaagattg gcaggtaaac cattcggttg actagacgat
    37801 attaacagat atcttccata atgaaataac aagttagtca agtagttact atacttttta
    37861 gtgttttcaa gaagtagatt cgttggaatg ctaagacaac ctttactata gtctagttta
    37921 aaatcaactc tattaaattg ctcctgatat ttttttacat gttcatcttt ttctgtaaag
    37981 taatcaatac tactaaattc tccctgaaga gaagaaatat ctatatttcc ccaataatcc
    38041 gtcattgatt tgagataaag aaatacctct gtagcattcc gaataactat tgtctctccc
    38101 aatacactta cttcaccatc cgtaacctta gaatgacata ctactttaaa ctgaacacct
    38161 tttctacctc cagcagaggc cgacattaaa attgtacttg aatccagttt agatacttcg
    38221 tcattaaacc gtttatttct acccaaatta atgtttaaat ttaatgtgtt ttgaactgat
    38281 gacactatac ggcaacataa aatattctta ttaaaactcg taaaatattc tctttttatt
    38341 tgtaaattac aactattagg ctcaaacaca acattagaaa tagctgtatc taaatctagc
    38401 tctctttcat acaatgaaag agcacaagac tgaatatcta tatgctcaat gtaaagttcc
    38461 ccaagtaatt catagtggct ttgatctctt ggggtagcaa acattgttaa ctttatcaat
    38521 tcttcggctt tctgaatttc tccatctaaa agatattccc gaattttttt aagatgcaat
    38581 agtgagtctg gattatttct atctgacttt cctctatacc aaatagtctc atcgtttagt
    38641 tgaatacatt cttttgtagc tgaaccataa atcataccac ctaaatgacc gttcccaatc
    38701 ggcaaggctt cattccaatt tgcggcagct ttcttatacc ataatttcac tctttacctc
    38761 tcttccaaaa tggaggtgat atcccaaata ccacctccac actttctact acttcaaaat
    38821 tcctaaaaca actaggataa ctccaatagc cataacacta aagattagta caaccggatt
    38881 ctttcctttt ctaattaatt tacacattaa taaagtcaaa gccataggga taaatcctgg
    38941 aattaatttt gtaatcattt cttgaacaga aataacaagt tccccctgct taaattctaa
    39001 tccaaaatta ataccaacca ttgatggaat caaaccaccc actagtacta gccctaatgc
    39061 tgtcgccata ctcgtaacgc gattcaatgt tccttttgta ttattttctt ggataagact
    39121 agaaccctta gtatacccat atttcaaacc gaaatattta acaggaatat taataatatt
    39181 aaacaatatt aaggcgataa agatacctaa agcaccgccg tctttagaat aagacgcacc
    39241 aatactaaaa cagataggaa ctagtgtcag ccagaacaaa ctatctccta gaccagccag
    39301 tggccccatc aagccaactt taataccagt aattgaagct gcaccttcat ttccttcttg
    39361 ttcttccata gcggaagtaa ctccaagaat aaatggtgcc gctgtttgat gagtattgaa
    39421 aaactcaagg tgacgtttca ttgcaggaga agctgaatct ttgtctgggt atagtttttt
    39481 caatactgga agaattgtat atagaaaacc taggttctgc attctctcat agttccatga
    39541 agaaccatac ataaaacttc gtttgaaaac ttttttaagt tcaactttag ttactttatt
    39601 attcatcata gatcaagatc ctcctcaaca tcactacttg aagttgtttc ttgtggttta
    39661 cttccaatca tatcgtagaa gtatgctacc gcaataccaa ctagtgagat cccaatggtt
    39721 gacattcctc catacacaga acaaatgaat ccaatcaaca agaataccca catatttttc
    39781 ttgagcatca tatttaaaag cataccaaaa ccaattgaag gtagtaaagc acctgcagag
    39841 ttaagtccct gcataacgat tggtggaacc ttagcaaaca agtctgccac atattcccct
    39901 ccaagcataa tagctaggaa aattggtaca attttaaata acgtgattaa aaccaaactt
    39961 gaataatgat aaaaaccgat ctttgaataa tctccgtttt tagcatcatt atcagctttt
    40021 ttcacaaaat aaacatctaa agtttttgca agaacatcca actgttgggt agcaactgca
    40081 attggaactg ctatagcgat accagcagtt tctccttgac cagataaaat accaaatgca
    40141 gtaccaataa tcgcacctga aatagtatct ggtggagtgt aacctccaat acctgttaca
    40201 ccgagccaag ttaattcaag agctgaacca ataagaacac cttgggtgaa atctcctaag
    40261 actaagccaa ccattgcact tgtaactaag ggacggtgaa tcataaataa cggtccatta
    40321 tagtcaatag tggcaataat cccaactaat gtcaccagta atgcttgtgt gaatagcata
    40381 tactgtacct ccttaaatta tttttataaa aatttttcca acattgtaac tttatcatta
    40441 ggaaccattt gaatttcaac tctcgttccc ttatcaacta ttttcttaaa ataatatttg
    40501 tcttcttcac ctagagctac acctcccgtt accttttcat tttcctccgt tttactcatc
    40561 tgtcctacat tgaggtactc caattttaaa tttccttcaa tagaatcata cacatctttt
    40621 ggatttgtat atatcagcat tgttctcttt tttattggca cagagtttaa aacttccaca
    40681 aaccgtttta cactaaagaa aacaattttt aaacctaccg gtgcagaaat ctttaaaata
    40741 gattgtcgtg ttttatcttc tgagatgcga tcattaacaa tgataacttg ctcaatatca
    40801 tactttttta gccacgtagt gacaacttga ccatgtacca gacggtcatc aatacgaaca
    40861 aactctatag acataaatcc tcttcctcct ctacgttaag ttgttgttta acattaaaca
    40921 aactattttg agcattttga acaatttctt ctaaattgat ttttgaatca taacttgata
    40981 ttaattccac taggagaggg atattaaacc ctgttacaat atcaactgaa tccaaattta
    41041 aaaaccgtga caaagccaca ttattaggac ttcctccaat caagtcagtc aaaacgataa
    41101 cctcttgatt tgagtctaac agttcattta cttgattttt aaaataatgt tcaaactcta
    41161 caatattctc tccaggcatc aaacctaatg tcctaactct atcatttgtt gtctcaccaa
    41221 caaacatttc tgcggtcatg agagctccgc tagcaaaatt accatgactg gcaactaaaa
    41281 ttcctctatt aaacattttc tctttcaaca actactcctt tcttaaggat aatattagca
    41341 taaagtgaag tttctcctgt agcaacaata gcataagctt tcttactacg ttcataaaag
    41401 tcttctcttc taagataagt aatcgtttta agatctgtac catgaccttc aatcatctgt
    41461 ctataggtac cccatatctt aggaatatca tcacccgaaa caacgttcat aaactgaatt
    41521 gaactatcga cgtaactatc taatggcatt aaatacagaa tggaatctaa taattctgga
    41581 atatttacac catcacaacg aattagctta tttgcacatg aggcagaagg ataattcgcg
    41641 tcagctaata ctatttcatc tccatgtccc atttccatta aagtcttcaa taaatctgga
    41701 gaaatatttt tcggtatatg ttttaacatt aatatcctcc ctattttctc tgaccgtatg
    41761 ttttaaattt ttctgccatc aattccatct cctcatcagg aagaactact ggctctccaa
    41821 aattcttagc taaacaataa atttttgcac aatattcaac ttcttcaaca atattaaatg
    41881 cattcaataa attttgtgca cctgctaaaa ttccatgatt cgctagtaaa actgctctac
    41941 gaccttccat tgctttagct gcattcacag ccaattcttt cgtgccatat gttgcatact
    42001 cagctacccg aacatctttc cctgccactg caatcatata atgactcgct ggaagtggtt
    42061 ctctgagaca agctaatact gttgcataag ttgtatgagc atggataatt gcatcgatat
    42121 catcacgagt ttgatattga atcaaatgca tataccattc gctagatggc aagcgttctc
    42181 cctctacaac atttccatta atatccatca ctacaatatc ggattctttg atttcaaaga
    42241 aatcaatacc cgacggggta attgccatca attgtttttc acgatcgaaa acgctgagat
    42301 tcccacctgt tcctttcgtc aaatctgttt ctactagctt cttaccatat ttaattaatt
    42361 cttgttttac atctgacatc cttgtcctcc tcatatcaaa acactaaata tttttcaatt
    42421 caccaattat ccccccttcc tgcacaaaag ctaagaaggg ggagggaggc aaatttacaa
    42481 actctcaatc tttttaattc ttttgggagt aataactctc taattgtaga aactcctcaa
    42541 taacatggtg agcctcttcc atccctttta attgtcccat agctatgagc tgcacaacaa
    42601 tattccccac agctgtagcc tcagtcaaac ctgtaagaac ctctttacca gttctatcag
    42661 caatcatttg gttaaagtaa ctggctctag cacctcctcc aatcacatat atcctcttat
    42721 aaaccttatg agttagttct tctagtaact ctatcgcttt cctatacgtt tcagctaggc
    42781 tttcataaac aatcttaaat agttgtccat ctgtccactc tctagtttca tgatgataag
    42841 ctagatattc tgtcaaagtc ttgtgcatat cagattctgt tgcaaattca gttgattcag
    42901 tatcaatcag aggaagattt tctttttctt tctccaccat tgtcctaata tcatcaaaag
    42961 aataggcttt ccctcttcgt tcaaatgaac gtcttagttc ctctatgatc cacaaccctg
    43021 tacaattctt cagaaatgta atcactccat ctttaccgac ttcatttgta aatccataac
    43081 tgaaggattc ggtagtaaga agcggtgaag taagttccac tccaaccaaa gaccaagtac
    43141 ctgatgaaat aaataaacta ccttctgtct taggtactga gacaatcgcg cttgctgtat
    43201 catgactaca aacattcaca acaggaatat cgcctaaacc atactccttt tttatccttc
    43261 caagaacatt tccctctgaa acaatctcag gaagtaaaga tgaatccaat tcaaatagtt
    43321 ttaagatatt ctgattccag ttttgactcc taggatcaaa taattgagtt gttgaagcaa
    43381 tgcttttttc tgtagcaaac ttacctgtca agagataatt aaacaaatct ggcattaaaa
    43441 gaatcttatt ggtcttatag aaagagtcag gagattcttg acgtgcctta aagagttgaa
    43501 acaaggtatt tatctccata atctgatttc ctgtctctga atacagtttt tctaattcag
    43561 tcatttcaga tatttccttt aacactccct ttgttctttc atcacgataa tgaacaggtt
    43621 gtaataacag cttaccttca ttatcaatca gtccaaaatc aactccccat gtgtcaatac
    43681 cgatagataa aatcttgtaa ctagtattag ccaagcggat actttcaaga attttagcta
    43741 gtagaaagtc aatatcccaa gataaatgcc cttttactct aataggtaga ttagaaaagc
    43801 gatttatttc ttccattact agtttatttt cagaaaggta accaacgatt gctcttccag
    43861 aagtcgcacc taaatctatt gctaaaaccg cttccatttt tcttctctct tcgtccttga
    43921 ttaactttat tataatcccc acgttttatt ttttcaatat gtgaacgctt acttgaataa
    43981 tgttcaaatg ttaacccaat attcataaaa ataattcaaa ttcctccaat ttgtgctata
    44041 atatagttga aatgataaat taggaggagc ttatgataaa agatgaacgt gtacttgaat
    44101 tgattgaaat tattaaaaag aaaaaaagaa ttgccgtaaa agagctggca gaaatcactt
    44161 tctccagcac aagtacctta cgtcgtgatt taattttctt agaaaatcaa ggtcttatca
    44221 aaagaaagca cggatacgtg accctgtcct ctatgaacac aattgaactt tctcatcaaa
    44281 tacgggaagg agaaagtact aggcaaaaaa gactaatcgc tagtctcgct aaagacttta
    44341 ttcggtctgg tatgtgtgtt tatctggatt ccagtactac tgtctacgaa ctttgtccct
    44401 atctttctga acttgataat ttgattattt ttacaaatgg tttacatact gcacaaaccc
    44461 tatctgaaac tgttaaagat agctccaaaa tctttatcac atctggcgag gtcaaacatc
    44521 aatcctgttc cgtggtcaac tatgataagg aaaattcttt attagatcat tttaatatcg
    44581 atttagcatt ttgttcagca agaggtattg atgaccaata tgtttatgaa gcttctctca
    44641 gccaagctat ttcaaaaaag aatattattg acaaagccca tgaaaccatc ttactgattg
    44701 atagttctaa attttacaag actggatttt ttaaaattaa tcccctctcc aaatacacaa
    44761 cctttatttc agacaccgtg ccagatcaaa aattattaga cgcagtcgaa ttatttgatg
    44821 gagaatgggt ttctgatatt caatgaaaat caaataggaa gctagtctca gcttgctcaa
    44881 agtacagatt tgaaaactga tgaagtcagc tcgaaacact gttttgaggt tgtagataga
    44941 actgatgaag tcagtcacat atatacggaa agacgaagct gacatgatgt gaagagattt
    45001 tcgaagagta ttcgttctgt ctgctgactg atttacaaat attcaccaca tgacattatt
    45061 ttctcagcaa ccctaaaaac agaggctgga caaaaactca atttcaggag aaaatggagt
    45121 aaaccttccc acaataaaac gcatagtatc aagtttttgc acacctgata ttatgcgttt
    45181 ttctgatttt aaagactttg tcgcctagac cctatatttc aagaattaag tgaccttgat
    45241 gatctaaatg tattgtggta tactattttt gtcatcggtt accgattacg ttcctatggg
    45301 ttcgtgagag gaggtgaaac taatgagcct tatcatagag ctcgctctta ctattatagc
    45361 ggatgttata gctggaatta tcttgtattt cgtctgcaga tggctagata gtaagaagta
    45421 gaccgagtga ctagcctata aacacccgtt aaatcgctaa gatacgtcaa aaaagccctt
    45481 aactacggcc atagttaggg gctttggtgt tctaatgaac cttatcaatt aactacattt
    45541 tagcatataa tctacaatag ttcaagcatt aagtgaggtt gatgatctaa atttagtgtg
    45601 atataatact tttgtcatcg gttaccgatt acgttcctat gggttcgtga gaggaggtga
    45661 aactaatgag ccttatacca gagcttgctc ttactattat agcagatgtt atagctggaa
    45721 ttatcttgta tttcgtctgc aaatggctag atggtaagaa gtagaccgac tgactagcct
    45781 ataaacaccc gttaaatcgc taagatacgt caaaaaagcc cttaactatg gcactagtta
    45841 ggggctttgg tgttctaatg aaccttatac actaactaca ttctagcata taagcccaga
    45901 tatttcaaga gttttattta ttgtttaaag ttctgaaagg tctataatga agttagccat
    45961 ctagtatcaa aaaaccgact agctcttatg aactagtcga tttctcatca atgcgccaac
    46021 atttcttggg cgatttcttg gccagatagg ttatctgggt agtaggttgg ccagttgtcc
    46081 atttcttcaa agagggcttc ttggcttgtg cctccaaaga agatatggaa atgttctgcc
    46141 ttaactgggg caacattgtg gtcactaaac tgaacatact tgaattgtcc agcgtcagca
    46201 tctgtggctt caaagaggaa acgcacgcca cgattgcctt tcttgtaagt caaaattttc
    46261 ttaccgacat acttgtaagt gtatttcttg ctttgtccac cttgaacaaa ttccatagta
    46321 ttatcagtaa tgttaatctt agtcacatct gtctgatagc cttttgtata gtaagccttg
    46381 tactcagcct gggtcatctt accagtcaac ttagccttgt agtcaaagac ttggtcaaac
    46441 gtgccgtctt caaggaaagg ataaactgat tgccagttac ctgcatagtc actcaaggtg
    46501 cggtccttga cagctgcatc ctcgaagtaa ccattttgga ctgtcttggt atcctctgcc
    46561 ttttcaggtt cgattgctgg gccttcttgg tctgttgttt gtttcaaagc cttgaggttt
    46621 ttctccatca cggaaatgta gttttctcca gccttggtgt cctcttctgt cagactttct
    46681 aaaggattga ggacatcagt tttgacacct gcttcttttg aaagtgtgtt agcaagggct
    46741 tgtgaggcat tttcttcaaa atagatatag gcgattttat ttttcttgac atactctgtc
    46801 aattctgcca agcgagcagc tgatggctct gcatctggag aaagtcctga gattgcgact
    46861 tgtttgagtc catagtccaa ggcaagatag ttaaaggctg cgtgttgagt cacaaagctc
    46921 ttttgttttg cttgagacaa gccttctgcg taagccttat ccaaggcttg caatttttcg
    46981 atataggcag ctgcattctt ctcaaaggtc tcttttttat caggataatc tgctgacaag
    47041 ctgtcgcgga tgtgctctac tagtttaatg gcacgaactg gtgataacca aacatggggg
    47101 tcaaactcat ggtgatgacc ttcttctcca tggtcatggt ctccctcttc ttccttgcca
    47161 cctggcaaga gcaacatatc gcctgtcgcc ttgatggttt tcactttttt cttatccaag
    47221 gtatctagca atttaggtac ccatgtttcc atgttttcat tttcataaac gaaggtatct
    47281 gcatcttgga ttttggcaac tgccttggca gatggttcgt attcatgagg ttctgtccca
    47341 gcaccgatta ggagttctac attagccgta tctcctgcga cttgcttggt aaattcatag
    47401 acagggtaaa aggttgtcac gatattgagt ttaccatctg cctgtttttg attggaacaa
    47461 gccactaaaa acaaggcaca tagactggct agtaataagc taattttttt cacgttcgtc
    47521 tcctatttga taaaacgtct tactaaactg attagtataa agacagttac aaaaataatg
    47581 gtaatacttg cacttgcagg tgtttctgca tagtaggaaa tgtaaagtcc tgctaccatt
    47641 cccaaaaagc caatcgcact ggcaagcagc ataaccgatt taaagttttt ccccagacgc
    47701 agggcaatac tagctggcaa gaccataatg gtcgatacca gaagagctcc tgctgcagga
    47761 atcataaggg caatagccac ccctgtcacc atgttaaaaa gaatggacat ggtacgaact
    47821 ggcaagccat ccacaaaggc cgtatcttcg tcaaaagtta agatatacat aggacgaaga
    47881 aagagaaagg tcaaaatcaa aacaaccgcc gcaatgacaa agagggaaat gacctgttct
    47941 tcactgatag tcacgatcga accaaagaga tattggtcca aactcattga actcgagctt
    48001 ttacccttgc tcatgacaat cagagaaaca gccagacctg ttgacatgag gatagctgtc
    48061 ccgatttcca taaagctctt gtaaaccgta cggagatact ccagaaagac cgccgcaatc
    48121 aagacaatgg caatagtaga aacagttgga gaaatcccca aaaccagacc aaaggctaca
    48181 cctgaaagtg agacgtggct aagggtatca ctcatcaaac tctgacgacg caagatgagg
    48241 aaggttccca ataccggtga gaaaagactc atagcaataa ccgccaaaaa ggcgcgttgt
    48301 ataaagtcgt aagataataa actaagcatg gcccacctcc tggccattct catgaacatt
    48361 gaaacaacgc catggcgagt cttggttacg gactagatga atattgcgat ccgcataatc
    48421 cttaacttct tcagggtcat gggtaatcat caaaacagcc ttgccatgat gatgggcgct
    48481 gtggtgcatg agttcgtaaa attcattttt acttcctgca tccatccccg ttgtcggctc
    48541 gtctaggata aacacatcag ggtcagaagc aaacatacgc gcaatcaccg ctcgctgctt
    48601 ttgtccccca gatagagacc ccaagcgttt gtctcgatgt tcccacatgc caactgagtc
    48661 cagactagcc ttgatatgct cctcatcatg agcattcaaa cgacggaacc agccttttct
    48721 cggatagcga cccgacttga caaattcata gaccgtactt ggaaaaccag cattaaaact
    48781 ggcaatttgt tgaggaagat aggctattct caatttctta ccttgcgtat ttgtctttga
    48841 aatagccacc tttccaatgc gtggttgcag aattccaaga ctagccttga tgagcgtcgt
    48901 cttagccgct ccattttccc cagtcaaggt aacaaattcc ccactatcaa cacaataatt
    48961 gatatgttca agaacaggct ccttatcata atagaaggac aaatcctcta ccgtaatata
    49021 tctcattatt tgatttctcc tactaaagca gtcaaaaacc gctgaatcac tttttgttca
    49081 tttggagtaa actgagtcgc cacttgttca taggttaaaa gtgtatgctc atggtgatgg
    49141 tggtgctcct cagcgattgg acgagccaag tcagtcaact gataaaaaat cacacgcgca
    49201 tctttagaat ctttagatgt ttccaacatc ccttccttga ccaaagactt aatggccttg
    49261 gtaactgccg cctgactgac attgagacga cgggccaatt ctgaatttgt taaagattcc
    49321 tctgacaaga gcataaggat atgctcctga gtattggtca gggccacctc gctagtgcaa
    49381 tgacctatta ggatttcatg ctgattttcc gcctgcaaaa tcacctcatt caaaaaagca
    49441 tcgatatcct ttgctagctg tctcatatct gactcctttc cttttagact tctctttttt
    49501 aagagaaaaa tactattctt tgacattttg tttaccagtt aattatatca caagcaaaaa
    49561 aagagtcaag aaaaaacgtg aaaactagtt tcattcttga actcttctat attatattat
    49621 ctattgaaat tctttgacat ctccatcata agtcgcccaa tctttgctga aaaagcgctc
    49681 attcagatgg taagtcggag ctggtgtggg attggatagg aaaggatcaa ctgccttgtc
    49741 aaaagccaac caacccaacc aaccaaggtg aatggtgtcc ttcataaaga aaggctcccc
    49801 gccgtcctta gaaaaatctg ctatattggt aaaaccttga ctttccaact ggtagcgaat
    49861 cttctgcacc gtttgttggt acatatcctc tcgtagacca gcatagtcca tccatttttt
    49921 attaacaggt ggaatgataa aaatcgggtt taccttagat ttagaaaact gtgttaaaac
    49981 caactgcaag tcattatact ctggcgactt gagataggta aagcttttct gagaatcctt
    50041 taatttcttc aaatccttct tgatctgctc attatagaaa taattttcca ttcccatctc
    50101 attattggaa gtattttttt cagcatctgc tttgacaaca tcttctattg cctgataaga
    50161 aaactggtct ggcaagattt ttaaatactt agctacatgc ttatcgtagt taacatagcc
    50221 tctaaccgaa aactgaccaa aaaaggaagc ttggcgttca ttaaaacgag ccaataattc
    50281 aatcatttca ttgtctgctg tcgacaattc ttctttactt gccaacttct gaaccaggtc
    50341 cttcatagct acgtttggga actgttgcag taagcgagtc gctgcatatt gactagcctg
    50401 atccccagat tgatgtttca gaaaactagt caactggtct ccattaaaat actgctggaa
    50461 ggctgctgga tcatagccat ttttactgaa ccactgaggt gagataacat acacaacttg
    50521 tttattctcc agctgtggta acatctgttg cattccaaaa tattggttaa gcgatgcagc
    50581 tcccccctgt cctaaaagat aaggacggta ggaacgattg tatttctcag ctaataccgc
    50641 aggatgagca ccgtcaaaac gaagccattc actagagcca aagaagggaa caaaacgcac
    50701 atttggatca gatagtgctc tgactttttg acttcgctcc ttaaaactat cgatagtagt
    50761 agccactgct gaacgctttt cagctcctag attatgatgc atctcagtag gataaaagaa
    50821 aatgagcaga aaaaccaaca aaccagcgat caagaccggt ccgaagatca tccataagcg
    50881 tttaagcatt ttgtagctcc acaataccag ctatgatttt attagctgta ttccagtcgt
    50941 cacgaccaaa ctctgttaca gggacacgaa tgtcaaaacg gttctcaatc tccacaatca
    51001 actcaaccgt tcccatacta tccaagacac ctgcatcaaa aagatcttca tccatcatgt
    51061 cagaaacatc ttccataaac aactcatcaa taatttcaat aacttctgat ttgatatcca
    51121 tattttattt ccttttattt tttaaaccat agattattca agaatccaga aaagattaag
    51181 aatgacaaca tgacaacatg gaaagtgaca accatgccaa gcaactgaat ccagcgattc
    51241 tcaggtaggg cagccttccc tgcttttttc cgttccttat tgagcgtttt tttcttgcga
    51301 acccaggcat cattgatgac caagcctagt ccatgaaaga gtccataggc gatatagtac
    51361 caggtcacac catgccaaaa tcccataatc agcatattta caatgtaggc catgcttgag
    51421 gttacattac gatttttaaa gactttcttt ctggttaaca ccatcaccat tcgcataaag
    51481 acaaagtcac ggaaccagaa ggacagactc atatgccagc gattccaaaa ctcctttaaa
    51541 tcccttgata aaaagggctt gttaaagttg atagggctac ggattcccat caagtttgag
    51601 atggccaaag caaacataga ataacctgca aagtcaaaga agagttccag accaaaagta
    51661 tacataactg ccaaggcata gagattaaag aagccacctg actgcaaggc taaattcttc
    51721 agaggaggta gtaaggtctc tcctaaaaca tgagctagga taaacttata caaaaagccc
    51781 cacatgatat agcggacaga ttcatccagc atatccatca actcatctcg ctcaggaata
    51841 gcctgataat tttcattaaa tcgcttaaag cgatcgattg gaccactcga gaaagttggc
    51901 atgaagagaa ggaaacggag gaattcccag agggtaaaat ccttaatcac tccatctctc
    51961 agctcgatga caatcccaac cgaacgaaag gtaaggtaag aaattcccaa gaacccaagc
    52021 aaagactgcg ttccattgat agctggttgc accttgacaa agataatcgg aagtagggac
    52081 agaaaactaa ctaagtagaa gacccacttg ccatccttgc tttttcgata atgcttgtag
    52141 aaaagcagga gcaatatttc ccagcaaagg taaataccca aggcagctag ttgattggtc
    52201 tttccaccca ccaacatggt gacaataaag aagagactta ccaacacttc ataccaggca
    52261 aagcgtttct tgaaaaagag acctataaag atgggcaagg ttgcagcaat cacataaaca
    52321 aaatactgag gattgccata tggctctaaa tgaggaagct gttgaaaaaa ctccatcatc
    52381 tcttattcac ctcgttaatc aatcctttga tgtcaatctt tccatttgga gttagtggca
    52441 aactgtctcg gtaaaggaat ttagatggca tcatatagga catcatgatg tctgtcaggt
    52501 cttccttgat ggccttggta atatcgatat ctcgctcaaa ctgctcacga acaccgtctt
    52561 ttaagatgac ataagccaat agattttgta ccttgtggtc cttgttatag cgcggtactg
    52621 cgacagcaga ttcgataaag cgagacttgt tgaggttttg agagacatct tctaactcaa
    52681 tgcggtaacc gttaaactta atctggaagt ccatgcgtcc gccgtagaga agcaagccct
    52741 catctgtcat ggttcccaca tcgcctgtgt gataggctgg cagatcttca aactcaaaga
    52801 aggcttctgc tgttttttca ggattgttca tataaccttt tgaaacagct ggcccagaaa
    52861 caatgatttc tccctgctca ccatttggca gtttatttcc ttcctcgtca atgataaagg
    52921 ttggagaatc agccttggta tagccgattg gtaggcgttt gagagtcgct aacatctcgt
    52981 ctgtcacggc aactgctgac agagctactg tcgcttctgt tgggccgtaa gcattgatga
    53041 tacgggcatt tgggaaacgc tcgcgcagtt tttgagctgt tttgaccgtc aattcttcac
    53101 catcaaagta gaaatgcgtg attccaggca ttttctcact gttgaagtat tcagacaaca
    53161 tggccatatc tgcaaaggat ggtgttgatg tccagatagc gattggcaat gaaaagatag
    53221 ccgcaaagag ttgcttaaag tcctgagtga tgactgaagg aagagtgaaa agcgtaccac
    53281 caagtgccaa ggtcggtgcc caatacatga cagacaagtc aaaagaataa ggtggctgtg
    53341 ccagcatttg cggacgactc ggtgtcgcaa attccttatc cgtaatcatc cagtttgtaa
    53401 agctgaggag attatcatgt gaaatctgca ctcccttagg cttaccagtc gtaccagaag
    53461 taaagataat gtagtaatta tcatctccct tgactggatg cgtgatttca tagttattcc
    53521 cttgggcaaa ggcttcttga acctgagcta gatttatcat tggtgtagaa acctgctcca
    53581 agggaaaggc tgaaatggca ataatcaagc ttggctctgc tacttctaaa atagctgaaa
    53641 ctcgctccaa ggccgaatgg ctatcaattg gaatgtaggc atgacctgac ttagtcagcg
    53701 ctacaaaggt tgccaacatt tcatattctt ggccaccaaa aacaaccaca ggagacttct
    53761 caggcaagcc tagttggtca atgactgcag ccaaactatc cgaatcagcc tttaaatcgc
    53821 cataagtgtg ttcctgcccc aaaacattat agacaggata gctaggctgt gtctgagcaa
    53881 aatgctcaat ggtttcaatc atatctgcta ttggtttatt tgacacaata gggattctcc
    53941 ttcaagttaa aattcattat agataaagct tccttgaccc tgaccaagat agctaaagaa
    54001 gtaaagcagc cctagaaaga taagaaaata caaggctgtc cgaccaagaa agaggtacaa
    54061 ttcttttctc tgtttcatca agaaaaacca ttcatttctg taatttttcg ctaaaataag
    54121 agtgattctt actagcttat ttttctacca ttgtaccact ttatatagta tcttttcaat
    54181 tgtttaccgt atgtttccaa tagatttcag cttattttaa ggattataca gtttttctat
    54241 gtatattttc aaatagagtg atcctgcctc aaaactccat ttcaggagac aatgaagtaa
    54301 atcttcccat aataaaacac acaatatcaa gttttttcaa cacctgatac tatgcgcttt
    54361 tctgattttt aaagactttt taaccactct ctcatttaaa ataatctcgt ctgatataaa
    54421 ttaaaatagc ttctatcatc agacaaatgg ctgatagcca aaaactgatg ctaataccaa
    54481 aactctcagt aatatagctc attagcaaaa caaatactga aaatgctaat gtagaaatca
    54541 cttcaagaac ggaatagaca ttaactaaat gattttcctc tactgtttcc tgaagaaata
    54601 cactttcagg aacttctttt agttgcgata acataccaac taaagctgaa aataataaaa
    54661 acatctgtgc gtttggaaaa tatagaatag tcagtgtcac tattgccata gctacaagag
    54721 gaaaaagaat actttcccat ttagcagcaa ggaacttttc agatagccta aaagcaatta
    54781 agccactaat tataatacca atagagtatg ctgtattaga atatccccag taactttccg
    54841 ttttatttaa taactccgtt acaaaaacaa gtataatgga agaaacccaa atcgtatttg
    54901 aaaaaatttc caataaattt gctgatacaa aaagtcttaa tctaggattt ctagcaacta
    54961 acttccaacc tttgagcaaa atttcaagat tagtttctga ctctaacacc tccacttcag
    55021 cgttaggaag aaataacatc agaaagctag aaatgatata caagactaaa atgataaacg
    55081 tggtaggtaa cagaccaatt gttgcaaaca agagtccacc taatccccaa cctatcaatt
    55141 gaacagcttc accagtcatt gataaggctg aattagcctt acccaaatcg gtcgcatagc
    55201 gtggcacaat agcataggaa acgggtgctg caaaaccatc tagtatggaa attgcaacaa
    55261 caaatagata ggtcaccaaa ggcgctacgg attgcattac ggtaaacatt cctaccagta
    55321 tcgccaataa tatagtcttt ccaaattgag ataaagataa aaccctattt agcgctaacc
    55381 ttttagtaac caacggaact aaaagactcg caacaaaaga ggatattcct attaagatag
    55441 gaactagtga tgtggcaatt actgattttg aaataatgta tatgttagca atgattgtta
    55501 ctctaaagaa aatatctgct aaatttgcaa ataattgaga gactaacaac ttgacaaatg
    55561 aattagacat gtagcgctcc ccctttagtt acaaactttg gaattaaatt tgatttttaa
    55621 tattttagca taaaatagca gaaaacaaaa gtgaggtttt ttacatgaaa aaacaaaaac
    55681 tattgccttt attattccta attttaggag gaattatgat tatcgttgtt ggctagtact
    55741 aagaagttag ttagttagtt agttagtaga ataattacat cttcaatcga aaaagagact
    55801 ggaaaaagtc ttaaaaatca gaaaaacgct caaatccttt ggcgctctaa gcttttctaa
    55861 tgatagattt agatagtcaa aaaaatatct gaaaagttcc caggatcgtc gtctcagcat
    55921 caaaaatacg tgaaatttgc ataattaaaa taaatttcag gggagt
//
LOCUS       DAVBOD010000010        46902 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 640-05
            SAMEA1012484-rid20186543.denovo.010, whole genome shotgun sequence.
ACCESSION   DAVBOD010000010 DAVBOD010000000
VERSION     DAVBOD010000010.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012484
            Sequence Read Archive: ERR059358
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 46902)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 46902)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979948.1
            Genome Coverage       :: 595x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:03:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,266
            CDSs (total)                      :: 2,219
            Genes (coding)                    :: 2,091
            CDSs (with protein)               :: 2,091
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 71 of 128
            Pseudo Genes (incomplete)         :: 50 of 128
            Pseudo Genes (internal stop)      :: 33 of 128
            Pseudo Genes (multiple problems)  :: 22 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..46902
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012484-rid20186543.denovo.010"
                     /strain="NIG 640-05"
                     /db_xref="taxon:1313"
     gene            59..772
                     /locus_tag="VQ862_000607"
     CDS             59..772
                     /locus_tag="VQ862_000607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000499426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjjG family noncanonical pyrimidine
                     nucleotidase"
                     /protein_id="HET3114997.1"
                     /translation="MFYKFLLFDLDHTLLDFDAAEDVALTQLLKEEGVADIQAYKDYY
                     VPMNKALWKDLELKKISKQELVNTRFSRLFSHFGQEKDGSFLAQRYQFYLAQQGQTLS
                     GAHDLLDSLIERDYNLYAATNGITAIQTGRLAQSGLVPYFNQVFISEQLQTQKPDALF
                     YEKIGQQIAGFSKEKTLMIGDSLTADIQGGNNAGIDTIWYNPHHLENHTQAQPTYEVY
                     SYQDLLDCLDKNILEKITF"
     gene            786..1433
                     /locus_tag="VQ862_000608"
     CDS             786..1433
                     /locus_tag="VQ862_000608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3114998.1"
                     /translation="MTTKKANITIEEYIEMSEVDFNEAVNYEFTSDTCQLANSIYQSL
                     FKFFDKKNFSGDLIFTWKSPSLVKEGDYIGRRDSQVDNLRVIGNIFPNYLTNRKYSLN
                     MNRNGCMGDFPHDFFDIYLDHVAKYAYEQKVNNIKEYYPLKRAILHQENALYFRFFSN
                     FDDFLEKNYLKTIWQVSKETPFSEMDFNMFKNISEKIIFERGSKMLNDLKSNYKK"
     gene            1571..2224
                     /locus_tag="VQ862_000609"
     CDS             1571..2224
                     /locus_tag="VQ862_000609"
                     /EC_number="3.2.2.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HET3114999.1"
                     /translation="MEHSSWHALIKAQLPEGYFGKINQFMEQVYSQGIIYPPKEKVFQ
                     ALLTTLLEEVKVVILGQDPYHGPGQAQGLSFSVPDSIPAPPSLQNILKELSDDIGVKK
                     SHDLTSWAEQGVLLLNACLTVPAGQANGHAGQIWEPFTDAVIQVVNHLDRPVVFVLWG
                     AYARKKKALVTNPHHLIIESAHPSPLSVYRGFWGSKPFSKANAFLKETGQEPIDWLR"
     gene            2234..2698
                     /locus_tag="VQ862_000610"
     CDS             2234..2698
                     /locus_tag="VQ862_000610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003012002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HET3115000.1"
                     /translation="MPQLATICYIDNGKELLMLHRNKKPNDVHEGKWIGVGGKLERGE
                     TPQECAAREILEETGLKAKPVLKGVITFPEFTPDLDWYTYVFKVTEFEGDLIDCNEGT
                     LEWVPYDEVLSKPTWEGDHTFVEWLLEDKPFFSAKFVYDGDKLLDTQVDFYE"
     gene            2711..3979
                     /locus_tag="VQ862_000611"
     CDS             2711..3979
                     /locus_tag="VQ862_000611"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000924471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotase"
                     /protein_id="HET3115001.1"
                     /translation="MLLIKNGRVMDPKSGLDQVCDVLVQDGKIIKIAPEITEEGAETI
                     DATGLVVAPGLVDIHVHFREPGQTHKEDIHTGALAAAAGGFTTVVMMANTSPTISDVE
                     TLQAVLQSAAKEKINVKTVATITKNFNGKNLTDFKALLEAGAAGFSDDGIPLESSKIV
                     KEAMEEAKKLNTFISLHEEDPGLNGVLGFNENIAREHFHICGATGVAEYAMMARDVMI
                     AYATKAHVHIQHLSKEESVKVVEFAQGLGAEVTAEVAPQHFSKTEALFLTQGSNAKMN
                     PPLRLESDRRAVIEGLKSGVITVIATDHAPHHVDEKNVEDITKAPSGMTGLETSLSLS
                     LTYLVEAGELSLMELLEKMTYNPAKLYNFEAGYLAENGPADITIFDAKADRLVDSHFA
                     SKAANSPFIGETLKGQVKYTICKGQIVYQA"
     gene            3993..4253
                     /locus_tag="VQ862_000612"
     CDS             3993..4253
                     /locus_tag="VQ862_000612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3115002.1"
                     /translation="MNYFRKRRERQAKSNSGIYCPAANRSKIQYETKEKADHAVQYDN
                     GGLVRSYYCRTCACWHTTSKSNKPPLSLKNYGLKLFGLDKSE"
     gene            4264..5625
                     /gene="pdrM"
                     /locus_tag="VQ862_000613"
     CDS             4264..5625
                     /gene="pdrM"
                     /locus_tag="VQ862_000613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000278532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium-coupled multidrug efflux MATE transporter
                     PdrM"
                     /protein_id="HET3115003.1"
                     /translation="MYKTKCLREKLVLFLKIFFPILIYQFANYSASFVDTAMTGQYNT
                     MDLAGVSMATSIWNPFFTFLTGIVSALVPIIGHHLGRGKKEEVASDFYQFIYLALGLS
                     VVLLGMVLFLAPTILNHIGLEAAVAAVAVRYLWFLSIGIIPLLLFSVIRSLLDSLGLT
                     KLSMYLMLLLLPLNSGFNYLLIYGAFGVPELGGAGAGLGTSLAYWVLLGISVLVLFKQ
                     EKLKALHLEKRIPLNMDKIKEGVRLGLPIGGTVFAEVAIFSVVGLIMAKFSSLIIASH
                     QSAMNFSSLMYAFPMSISSAMAIVVSYEVGAKRFDDAKTYIGLGRWTALIFAAFTLTF
                     LYIFRGNVASLYGNDPKFIDLTVRFLTYSLFFQLADTFAAPLQGILRGYKDTVIPFYL
                     GLLGYWGVAIPVATLFDSLTDFGAYSYWIGLIISLIVSGALYRWRLTVIMKRFESLAK
                     SKR"
     gene            5779..6747
                     /locus_tag="VQ862_000614"
     CDS             5779..6747
                     /locus_tag="VQ862_000614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine pyrophosphate-dependent dehydrogenase
                     E1 component subunit alpha"
                     /protein_id="HET3115004.1"
                     /translation="MSTLDKNLLLEMFRKMEEIRRMDLKIAQLVKKGKVPGMTHFSVG
                     EEAANVGAMLALNPDDLITSNHRGHGQAIAKGIDLNGMMAEILGKYTGTCKGKGGSMH
                     IADLDAGNLGANGIVGGGMGIAVGAALSQQMQNTGKIVVCFFGDGATNEGVFHEAVNM
                     ASIWNLPVIFYCINNGYGISADIKKMTNIEHIHQRSAAYGIPGMFIEDGNNVIDVYEG
                     FQKAVDHVRSGNGPVLIESVTYRWLGHSSSDPGKYRTREEVELWKQKDPIENLRNYLI
                     ENNIASAEELEEIQAQVKEAVEASVKFAEESPFPPLESAFEDIYAD"
     gene            6763..7755
                     /locus_tag="VQ862_000615"
     CDS             6763..7755
                     /locus_tag="VQ862_000615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000448722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-ketoacid dehydrogenase subunit beta"
                     /protein_id="HET3115005.1"
                     /translation="METKTMSFRDTIILAMSEEMRRDENVFLMGEDVGVFGGDFGTSV
                     GMLEEFGPERVRDCPISEAAISGAAAGAAMTGLRPIVDMTFMDFSVIAMDNIVNQAAK
                     TRYMFGGKGQVPMTVRCAAGNGVGSAAQHSQSLESWFTHIPGLKVVAPGTPADMKGLL
                     KSSIRDKNPVIILEYKSEFNQKGEVPVDPDYTIPLGVGEIKRQGTDVTVVTYGKMLRR
                     VVQAAEELAEEGISVEIVDPRTLVPLDKDIIINSVKKTGKVVLVNDAHKTSGYIGEIS
                     AIISESEAFDYLDAPIRRCAGEDVPMPYAQNLENAMIPTVESIKDAIRKTYNKE"
     gene            7973..9016
                     /locus_tag="VQ862_000616"
     CDS             7973..9016
                     /locus_tag="VQ862_000616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoamide acetyltransferase"
                     /protein_id="HET3115006.1"
                     /translation="MADDKLRATPAARKLADDLGINLYDVSGSGANGRVHKEDVETYK
                     DTNVVRISPLAKRIALEHNIAWQEIQGTGHRGKIMKKDVLALLPENIENDSIKSPAQI
                     EKVEEVPDNVTPYGEIERIPMTPMRKVIAQRMVESYLTAPTFTLNYEVDMTEMLALRK
                     KVLEPIMEATGKKTTVTDLLSLAVVKTLMKHPYINASLTEDGKTIITHNYVNLAMAVG
                     MDNGLMTPVVYNAEKMSLSELVVAFKDVIGRTLDGKLAPSELQNSTFTISNLGMFGVQ
                     SFGPIINQPNSAILGVSSTIEKPVVVNGEIVIRPIMSLGLTIDHRVVDGMAGAKFMKD
                     LKELIETPISMLI"
     gene            9080..10765
                     /gene="lpdA"
                     /locus_tag="VQ862_000617"
     CDS             9080..10765
                     /gene="lpdA"
                     /locus_tag="VQ862_000617"
                     /EC_number="1.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="HET3115007.1"
                     /translation="MPKAGVDMTEGQIVQWNKKVGEFVKEGEILLEIMTDKVSMELEA
                     EEDGYLIAILKGDGETVPVTEVIGYLGEERENIPTAGAASPEASSVPVASTSNDDDKS
                     DDAFDIVVIGGGPAGYVAAIKAAQFGGKVALVEKSELGGTCLNRGCIPTKTYLHNAEI
                     IENIGHAANRGIVIENPNFTVDMEKLLETKSKVVNTLVGGVAGLLRSYGVTVHKGIGT
                     ITKDKNVLVNGSELLETKKIILAGGSKVSKINVPGMESPLVMTSDDILEMNEVPESLV
                     IIGGGVVGIELGQAFMTFGSKVTVIEMMDCIVPAMDAEVSKNLRLILERKGMTILTGT
                     KLQEIIEENGQLRIKVEGKDDIIASKALLSIGRMPDLEGIGEVEFELDRGCIKVNEYM
                     ETSVPGIYAPGDINGTKMLAHAAFRMGEVSAENALKGNHAIAKLNLTPAAIYTLPEVA
                     AVGLTEEQAREKYDVAIGKFNFAANGRAIASDAAQGFVKVIVDKKYGEILGVHIIGPA
                     AAELINEASSIIEMEITVEEMLKTIHGHPTYSEVMYEAFADVLGMAIHSPKKK"
     gene            10829..11818
                     /locus_tag="VQ862_000618"
     CDS             10829..11818
                     /locus_tag="VQ862_000618"
                     /EC_number="6.3.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000873976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase"
                     /protein_id="HET3115008.1"
                     /translation="MKYIINHSNDTAFNIALEEYAFKHLLDEDQIFLLWINKPSIIVG
                     RHQNTIEEINRDYVRENGIEVVRRISGGGAVYHDLNNLNYTIISKEDENKAFDFKSFS
                     TPVINTLAQLGVKAEFTGRNDLEIDGKKFCGNAQAYINGRIMHHGCLLFDVDLSVLAN
                     ALKVSKDKFESKGVKSVRARVTNIINELPKKITVEKFRDLLLEYMKKEYPEMTEYVFS
                     EEELAEINRIKDTKFGTWDWNYGKSPEFNVRRGTKFTSGKVEVFANVTESKIQDIKIY
                     GDFFGIEDVAAVEDVLRGVKYEREDVLKALKTIDITRYFAGISREEIAEAVVG"
     gene            complement(11891..12961)
                     /gene="xerS"
                     /locus_tag="VQ862_000619"
     CDS             complement(11891..12961)
                     /gene="xerS"
                     /locus_tag="VQ862_000619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000817875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerS"
                     /protein_id="HET3115009.1"
                     /translation="MKREILLERIDKLKQLMPWYVLEYYQSKLAVPYSFTTLYEYLKE
                     YDRFFSWVLESGISNADKISDIPLSVLENMSKKDMESFILYLRERPLLNANTTKQGVS
                     QTTINRTLSALSSLYKYLTEEVENDQGEPYFYRNVMKKVSTKKKKETLAARAENIKQK
                     LFLGDETAGFLTYIDQEHPQQLSNRALSSFNKNKERDLAIIALLLASGVRLSEAVNLD
                     LRDLNLKMMVIDVTRKGGKRDSVNVAAFAKPYLENYLAIRNQRYKTEKTDTALFLTLY
                     RGVPNRIDASSVEKMVAKYSEDFKVRVTPHKLRHTLATRLYDATKSQVLVSHQLGHAS
                     TQVTDLYTHIVNDEQKNALDSL"
     gene            complement(13455..15005)
                     /locus_tag="VQ862_000620"
     CDS             complement(13455..15005)
                     /locus_tag="VQ862_000620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chloride channel protein"
                     /protein_id="HET3115010.1"
                     /translation="MEEQSEIVRSKKEFAFASSTILSQVGRGIIVGLIVGIIVGSFRF
                     LIEKGFHLIQGVYQDQGYLVRNLFVLVLFYILICWLSAKLTRSEKDIKGSGIPQVEAE
                     LKGLMSLNWWGILWKKYVLGILAIASGLMLGREGPSIQLGAVGGKGIAKWLKSSPVEE
                     RSLIASGAAAGLAAAFNAPIAALLFVVEEVYHHFSRFFWVSTLAASIVANFVSLLMFG
                     LTPVLDMPDNIPPMTLDQYWIYLVMGIFLGFSGFLYEKAVLNVGRVYDLIGQKIHLDR
                     AYYPILAFILIIPVGIFLPQIIGGGNQLVLSLTEQNFSFQVLLAYFLIRFIWSMISYG
                     SGLPGGIFLPILALGSLLGALVGVICVNLGLVSQEQFPIFVILGMSGYFGAISKAPLT
                     AMILVTEMVGDIRNLMPLGLVTLVSYIIMDLLKGTPVYEAMLEKMLPEEVSSEGEVTL
                     IEIPVSDKIAGKQVHELNLPHNVLITTQVHNGKSQTVNGSTRMYLGDMIHLVIPKSEI
                     GKVKDLLL"
     gene            complement(15021..15800)
                     /locus_tag="VQ862_000621"
     CDS             complement(15021..15800)
                     /locus_tag="VQ862_000621"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HII"
                     /protein_id="HET3115011.1"
                     /translation="MATIKEIKELLVTVKELESPIFLELEKDNRSGVQKEISKRKRAI
                     QAELDENLRLESMLSYEKELYKQGLTLIAGIDEVGRGPLAGPVVAAAVILPKNCKIKG
                     LNDSKKIPKKKHLEIFQAVQDQALSIGIGIIDNQVIDQVNIYEATKLAMQEAISQLSP
                     QPEHLLIDAMKLDLPISQTSIIKGDANSLSIAAASIVAKVTRDELMKEYDQQFSGYDF
                     ATNAGYGTAKHLEGLTKLGVTPIHRTSFEPVKSLVLGKKES"
     gene            complement(15787..16638)
                     /gene="ylqF"
                     /locus_tag="VQ862_000622"
     CDS             complement(15787..16638)
                     /gene="ylqF"
                     /locus_tag="VQ862_000622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YlqF"
                     /protein_id="HET3115012.1"
                     /translation="MATIQWFPGHMSKARRQVQENLKFVDFVTILVDARLPLSSQNPM
                     LTKIVGDKPKLLILNKADLADPAMTKEWRQYFESQGIQTLAINSKEQVTVKVVTDAAK
                     KLMADKIARQKERGIQIETLRTMIIGIPNAGKSTLMNRLAGKKIAVVGNKPGVTKGQQ
                     WLKTNKDLEILDTPGILWPKFEDETVALKLALTGAIKDQLLPMDEVTIFGINYFKEHY
                     PEKLAERFKQMKIEEEAPVIIMDMTRALGFRDDYDRFYSLFVKEVRDGKLGNYTLDTL
                     EDLDGND"
     gene            complement(16720..18228)
                     /locus_tag="VQ862_000623"
     CDS             complement(16720..18228)
                     /locus_tag="VQ862_000623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000291919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HET3115013.1"
                     /translation="MYYVTKTNSKGQPLYQVVEKYKDPLTGKWKSVTVSYTKNTSRAR
                     KQAEREVLDKIDRLTTSFESQFSPELITTFGELKENWFQTWCVSVKPQTIQRELLVMK
                     RLGKIIGDDFLLDRITPLLMKKSLNKYLEIYDASPSTMTHIKSTCNKIFNHGVLYNVI
                     KFSPMTAVKLDISLEKRRKAKERHDSKFLEIHELHAFFDVLSQCRNANYYDLAIVLLL
                     TGIRISEAAFLPSDIDFEKGILHIDKALQYHCLKVEQFHFDTTKTLNSIREVALPEAA
                     SEAIKRTIQRNKEFDAYMEKHPCPAFTHSESVFRTEYGSPITSSTFRQILKRIEGKLL
                     TNCLSDYGFKWVKHVTPHSFRHMHISYLQSNEMHIAVKDIMTRVGHANFETTMGYTHN
                     INRSQENTVKALNQFVENHNFHFEELKSYTCKYSRIIEKFIETSDNSNKVEFSVDEFK
                     DLLHLSPRYSPKNIISNLLLKIKKDIVKYHPQFDIKIVKSSENQIRGFSIAW"
     gene            complement(18313..18546)
                     /locus_tag="VQ862_000624"
     CDS             complement(18313..18546)
                     /locus_tag="VQ862_000624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000693750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HET3115014.1"
                     /translation="MNIKYISVENSIAEWADKKGILKRWDGLNQYTLNRWIKEMRENR
                     TFSMYVINPTHKLVFINLEGFESFLRWKQKRTK"
     gene            complement(18816..19040)
                     /locus_tag="VQ862_000625"
     CDS             complement(18816..19040)
                     /locus_tag="VQ862_000625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001845537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET3115015.1"
                     /translation="MLKRIRDLREDDDLTQEYIAKIVLNCTRSSYSKMEAGSRLISIN
                     DLIKLADFYKVSLDYLVGRVDNKEDHYSKK"
     gene            complement(19144..20973)
                     /locus_tag="VQ862_000626"
     CDS             complement(19144..20973)
                     /locus_tag="VQ862_000626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000237135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="HET3115016.1"
                     /translation="MVITKHFAIHGKNYRSKLIKYILNPSKTKNLTLVSDFGMRNYLD
                     FPSYEELVKMYNDNFLSNDTLYEFRHDRREVNQRKIHSHHIIQSFSPDDHLTPEQINQ
                     IGYETVKELTGGRFRFIVATHMDKDHIHNHIILNSIDQNSDKKFLWDYKSERNLRMVS
                     DRLSKIAGAKIIENRYSHRQYEVYRKTNYKYEIKQRVYFLIENSKNFEDFKKKAKALH
                     LKIDFRHKHVTFFMTDSNMKQVVRDSKLSRKQPYNETYFKKKFVQREIINILEFLLPK
                     MKNMNELIQRAEFFGLKIIPKEKHVQFEFDEIKISEQELVKANRYSVSYFQNYFNNKN
                     ETVVLDNKNLVELYNEEKLIKEKELPTEEVVWKSYQDFKRNRDAVHEFEVELNLNQIE
                     EVVDDGIYIKVQFGIRQEGLIFVPNIQINMEEEKVKIFLRETSSYYVYHKDSTEKNRF
                     MKGKTLIRQFNLQYEPQYMYRRIPLSKIKEKIEQLDFLVSAENSQNAFEDITKDFIAQ
                     ISYLENMIDHVQNKIDDLSNLEEVLLNDATNSSSNLENSIQGKSSVDTIEKDLYIYKG
                     KIETLKEQHREAINLFEMFNKTIKKYKKKQNTKSIKENEIHLE"
     gene            complement(20960..21325)
                     /gene="mobC"
                     /locus_tag="VQ862_000627"
     CDS             complement(20960..21325)
                     /gene="mobC"
                     /locus_tag="VQ862_000627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000401240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid mobilization relaxosome protein MobC"
                     /protein_id="HET3115017.1"
                     /translation="MEHRYRTNLKKVFLSDLELVKLNENISKSNCLSFSEYARRTLLD
                     PGMNFITIDTNSYQDLIFELKRIGNNINQIARSINYSNLITEVELNELRKGIEELIVE
                     VEKDFLIQSEKLRKFYGHH"
     gene            complement(21330..21686)
                     /locus_tag="VQ862_000628"
     CDS             complement(21330..21686)
                     /locus_tag="VQ862_000628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012775541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3115018.1"
                     /translation="MKRDIRSIRKQFRLTETEEKQILDLMREKGEDNFSDFLRKSLLL
                     SDGQKQMEKWFNLWKKQKLEQISRDVHEVFIIAKTNHQVTHEHVSILLTCIQELIKEV
                     EKTGPLSEDFRNKYMR"
     gene            complement(21982..22272)
                     /locus_tag="VQ862_000629"
     CDS             complement(21982..22272)
                     /locus_tag="VQ862_000629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001080188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3115019.1"
                     /translation="MNRKELYDDKLQLDYFSDSYLQFESDFYKYSALDIPLTFITDDI
                     LRTMAMSQKHYFKLNKSKSLDGRDHYFVFSIKMNKDSSGIRQYEYQRHCFNL"
     gene            complement(22262..22627)
                     /locus_tag="VQ862_000630"
     CDS             complement(22262..22627)
                     /locus_tag="VQ862_000630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000981955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3115020.1"
                     /translation="MMNRSYLPFESARVYQDRGMAKWMGFFLSEHSSSLWAEKNKEDI
                     SISLSLEEKVLFVRQLYTNVFPATFVFKFSNQRKVVSGIVKEIGKEFISIKSDTGFLR
                     LKWEDILDIQIEGEELHES"
     gene            complement(22624..24039)
                     /locus_tag="VQ862_000631"
     CDS             complement(22624..24039)
                     /locus_tag="VQ862_000631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006149971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Y-family DNA polymerase"
                     /protein_id="HET3115021.1"
                     /translation="MSWFDYSLEPQSDIAFIDMKSFYASVECVDRGLHPLKTSLCVMS
                     RADNSAGLILASSPMFKKVFGKSNVGRSYDLPFDVKTRKFSYYNARKQGLPTTIDYVR
                     YIEEWAKSTVIVPPRMDTYIAVNMEIQKIFQEFAAPDDIYPYSIDEGFIDLTSSLNYF
                     VPDKRISRKDKLDIISAAIQKKIWRKTGIYSTVGMSNANPLLAKLALDNEAKKTPTMR
                     ANWSYEDVEKKVWTIPKMTDFWGIGNRTEKRLHNLGIFSIKELAQANPDLIKKELGIM
                     GLELWFHANGIDESNVHKPYKPKSKGIGNSQVLPKDYIKQRDIEIILREMAEQVAVRL
                     RRSGKKATVVSIHLGYSKVEQKRSINTQMKIEPTNQTALLTNYVLKLFHTKYTSGAIR
                     NVAVNYSGLVDESFGLISLFDDIEKIEKEERLQSAIDAIRTEFGFTSLLKGNALDQAS
                     RTIARSKLIGGHSAGGLDGLK"
     gene            complement(24042..24725)
                     /locus_tag="VQ862_000632"
     CDS             complement(24042..24725)
                     /locus_tag="VQ862_000632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000492697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET3115022.1"
                     /translation="MFSPTKLKEKRESQGLSQSQLASSLGISRASYFNWESGKTKPNQ
                     NNLSKLSEIFNVDPRYFESEFEIVETYLKLTKKNQKATLHYATELLNKQNAKVVEIPE
                     RFAYKVYEKLSAGTGTAYFDDGNYDTVYFNRQFDYDFASWVSGVSMEPTYKNGSVALI
                     KQTGFDYDGAIYAIDWDSQTFIKKVYREENGLRLVSLNRNYPDKFAPYDENPRIIGKI
                     VGNFMPLED"
     gene            complement(24953..25723)
                     /locus_tag="VQ862_000633"
     CDS             complement(24953..25723)
                     /locus_tag="VQ862_000633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zeta toxin family protein"
                     /protein_id="HET3115023.1"
                     /translation="MEIQDYTDSEFKHALTRNLRSLTRGKKSSKQPIAILLGGQSGAG
                     KTTIHRIKQKEFQGNIVIIDGDSFRSQHPRYLELQQEYGKDSVEYTKDFAGKMVESLV
                     TELSHLGYNLLIEGTLRTIDVPKKTAQLLKSKGYEVQLALIATKPELSYLSTLIRYEE
                     LYSINPNQARATSKEHHDFIVNHLVDNTRQLEELAIFERIQIYQRDRSCVYDSKENTT
                     SAATVLHDLLFGEWNQVEKEMLKSGEERLKDLTNRNGL"
     gene            complement(25723..26199)
                     /locus_tag="VQ862_000634"
     CDS             complement(25723..26199)
                     /locus_tag="VQ862_000634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003042293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET3115024.1"
                     /translation="MIGKNIKSLRKTHDLTQHDFARIVGISRNSLSRYENGTSSVSTE
                     LIDIICQKFNVSYVDIVGEDKMLNPVEDYELTLKIEIVKERGANLLSRLYRYQDSQGI
                     SIDDESNPWILMSDDLSDLIHTNIYLVENFDEIERYSGYLDGIERMLEISEKRMVA"
     gene            complement(26269..26541)
                     /locus_tag="VQ862_000635"
     CDS             complement(26269..26541)
                     /locus_tag="VQ862_000635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3115025.1"
                     /translation="MFTKIFKKNQDNSDIFKKLIHRLSDMSVQDLEKIDRLLDIIFTP
                     EQESEQLKTETTYREETLDDTLKKAKNQLHKEQLEKNLERFRKNSQ"
     gene            complement(26579..26962)
                     /locus_tag="VQ862_000636"
     CDS             complement(26579..26962)
                     /locus_tag="VQ862_000636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000159213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chemotaxis protein"
                     /protein_id="HET3115026.1"
                     /translation="MTKDWNFNQPLESKSENQEDPDKIAALFRNHQGGNDVNYEAAFQ
                     KRKQAPVTESNSSSKPKVTEVRTGKETDITTSYQQHLKRLIADNNSDIESSQKKIEEL
                     HTLIDTKNKDNKKLQSIYDAISELH"
     gene            complement(26959..27192)
                     /locus_tag="VQ862_000637"
     CDS             complement(26959..27192)
                     /locus_tag="VQ862_000637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000152421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3115027.1"
                     /translation="MTIIERLEEKVTRQESKVARETEKLAAYKEQLETAMFATFKRRQ
                     SISHMSFEEALDHAFGKERQFDDSEFRKDEMSE"
     gene            complement(27243..28328)
                     /locus_tag="VQ862_000638"
     CDS             complement(27243..28328)
                     /locus_tag="VQ862_000638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toprim domain-containing protein"
                     /protein_id="HET3115028.1"
                     /translation="MEIEECKQISILDVANRLGISFKQVSSRVYEHPEHDSFRIFSTT
                     NTFKWFSRDIQGDVIDFVRLVKGISFKDALAFLSEEPFQKEAVQEKRERPFYYPLKRV
                     EDSNCSLARYYLTKCRGISEEIVQKMIQQGLMAQASWKTNETVELVIVFKSFDHRHKL
                     QAASLQGIYKNPALSRERLKTILKGSHGHIGISFDIGKPNRLVFCESFVDLMSYYELH
                     QQSLTDVRLVSMEGLKRSVVAYQTLRLIAEENQKLEFLDTVIPSKLLPLMNTIRDTTT
                     YFDNHPDLLTLAVDCDDAGKDFSDKLFQAGLPVLLDLPDNESGKEKIDWNDILREKKS
                     DLQLILESAKETLRNQPVRQTSQCLEL"
     gene            complement(28338..28979)
                     /locus_tag="VQ862_000639"
     CDS             complement(28338..28979)
                     /locus_tag="VQ862_000639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000933080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HET3115029.1"
                     /translation="MLNKVKTKALISVGAVAATSFILMMGYTAGQHSTAKQSRKEIEL
                     AAAKLVEDKQAEDKASILSSDTVKEFLTQYYTKEKLGENNTRIQPYMTESAYSQELTS
                     QNDAMNQVYKDYILDYHFEKADIFVNQTTNQAIAMVSYNVTYVSDLKNANQSKTNQTE
                     TRTVKLSYSKLPGKLLVNQVQVWKSGLDDLDKVTPKTLEESSSIPSLPNTTTK"
     gene            29139..29336
                     /locus_tag="VQ862_000640"
     CDS             29139..29336
                     /locus_tag="VQ862_000640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3115030.1"
                     /translation="MNKLKEENLRRALSHIERHKQAINTTNNSEDNDFHKLLLQFSYE
                     VYERIKANKKPYPNLDSDKVF"
     gene            complement(29350..29646)
                     /locus_tag="VQ862_000641"
     CDS             complement(29350..29646)
                     /locus_tag="VQ862_000641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000998899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3115031.1"
                     /translation="MNDLLLIPVIFLAVGGILILLWRLFLIASRLFLIGFVSFLIFVE
                     VYGIYLFFTEPTLYFDDIRQHGLTSFTAVYLFINLMLVLGFSWRFINSMNKEKM"
     gene            complement(29660..29944)
                     /locus_tag="VQ862_000642"
     CDS             complement(29660..29944)
                     /locus_tag="VQ862_000642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004263534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3115032.1"
                     /translation="MMEDTYYQLEEALVQGFQTPEEYQAYKELKEHYEEVTGDYSFSK
                     RELTSQLEISLQNHRGVDFEEHEKEEYLDLVQKLEEFDSSLATHYRQLID"
     gene            complement(30019..36249)
                     /locus_tag="VQ862_000643"
     CDS             complement(30019..36249)
                     /locus_tag="VQ862_000643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000453515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HET3115033.1"
                     /translation="MEVMKLLAMFRGTIPKDREKMDLFLRYQAQHFDEKWQDLVESFL
                     VEEGKIEEIPHVYSFHQDIISFLEASSENNDQDLESYTRNFGQAGLSKLSQLSNFEKN
                     LVLEVATYNLSTRFYIQSEKEKLTPLSELVCHQKQDVNLVNVYRVANNLSDRISRDIE
                     EFLLMVDSKELKKEVLEIHFEEKEGDVLAYLGSELMATLDTVTDLVHHEENYQQLPLT
                     QKLKIITHFDEVKAIREKSKQVAESLSPSSDIEQETEETNSFSNIDKIVEEALREYPI
                     GSQVSYKGQVFQLVSIENAQLNDLVRLELFKDSNQLFEENPILYLNSLEEIEQVLSHV
                     ELEKEDSEIEIDSSSESQEIDLFSYLEEENENEKEKEKDKETETLIVGIEETDVPVQD
                     FVFPDDLEDFYPKTNREKIETNIAAIELVKRLEKEGRQANPEEQELLAKYVGWGGLAN
                     EFFDELNPKYETERLTLKSLVSKSEYSTMKQSSLTAYYTDPMIIRQIWQKLLDDGFEG
                     GRILDPSMGTGNFFAAMPRSIRDKSELYGVELDSVTGAIAKQLHPNTHIEVRGFEEVP
                     YQNNSFDLVLTNVPFGNFRIADKNYDKPYMIHDYFVKHSLDLVRDGGQVSIISSIGTM
                     DKRTDNVLQEIKSNTHFLGGVRLPDTAFKKIAGTRVTTDLLFFQKDQAKNLNEEELVF
                     SGSIPFEEDKRVWINPYFDGKYNTQVLGQYEVRNFNGGTLNVKGVSETLVTEIMKAFE
                     NVEAPKQIDNSLKAPVFIQEEVDNSIPSRICEDLALYSFGYEGNQIYYRDTHGIRKSS
                     KVDEISYYVDEKGEFKAWDSSLSEHKIDRFVQLHLTDEEALDVYKSEEASKRGKYKGL
                     FKKTVFYESPLSDKDISRIKGMVDLRETYQALIEIQRHPDYSRSDFQILLSKLNRDYD
                     RFVSQFGYLNASVNRNLFDSDDKYSLLASLEDEYIDSKDQKVKYKKSLAFEKALVRPE
                     RVITRVSTALDALNSSLSDGRGVDLDYMVSIYPEHSQAAILDELGDQILMDPESYLRG
                     ERKYLSKNQFLSGDILNKIEVVQLLVEENNQEYDWNHALDLLESVRPPRIHLADIEFK
                     IGSRWIPQSVYGKFAFECFTNREFELSSPDVEQVIEVNPVDGQVHLRTSFAYRYPSAK
                     DSSLGVSGSRYDTGRKIFENLLNSNQPTITMTVTEGEKKKTITDLEKTSVLRAKEQHL
                     QELFQEFVSRYPEVQQVIEESYNRLYNRTVSREYDGSHLVIDGLAQNISLRPHQENAI
                     QRIVEEKRALLAHEVGSGKTLTMLGAGFKLKELGMVHKPLYVVPSSLSAQFGQEIMKF
                     FPTKKVFVTTKKDFVKARRKQFVSRIITGDYDAIVIGDSQFEKIPVSKERQMNYIEDK
                     LNELREIKTHSENKYTVKEAEQSISGLEKQLEELQRFNRDSFIDFENLGIDFLFVDEA
                     HHFKNIRPITGLGNVAGITNTTSKKNVDMEMKVRQIQEEHDFKNIVFATGTPVSNSIS
                     ELYTMMNYIQPDILKRYQVDYFDSWVGAFGEIQNSMELAPTGDKYQPKKRFKKFVNLP
                     ELMKIYKETADIQTQDMLDLPVPEAHIIPIESELTENQKLYLEELVMRSDAVKCGTVD
                     PSQDNMLKITGEARKLAIDMRLLDSSYSLADNHKLLQVVDNVERIYREGMGNKATQMI
                     FSDIGTPKKKDNGFDVYSEIKALLVDRGIPSKEIAFVHDANSDEKKNSLSRKVNAGEV
                     RILLASTEKGGTGLNVQSKMKAVHHLDVPWRPSDIQQRNGRIIRQGNENKEVDIYHYI
                     TKGSFDNYLWATQENKLRYIKQIMTSKEPIRAAEDIDEQTMTASDFKALATGNPYLKY
                     KMELENDLTLLENQRRAFQRSKDHYRHTISYCEENMPILEKRLSKYEGDIQQSEISKD
                     QAFSMTVGKQAFDQRAEAGESLHRLIRHNQADSKEFRTLASYRGFDIKMLSLPINQPL
                     PETFSVKIVGENQYSVSLDLYSPLGTIQRLQHTIDHIKEDQVKTQNLLDELKDKWTTA
                     KVEIEKNFPKEEDYQTKKAEYDVLAPLIETETDLDIIDQALRQFHEKGKEKQEQLSFE
                     LD"
     gene            complement(36297..36707)
                     /locus_tag="VQ862_000644"
     CDS             complement(36297..36707)
                     /locus_tag="VQ862_000644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014713375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell envelope biogenesis protein OmpA"
                     /protein_id="HET3115034.1"
                     /translation="MEGIYQRDSDQDGLTDAQELALGTNPLSADSDGDGRSDLVEVEE
                     GTNPLEKDLQDIDQTSITEPSSVFMEMKQKISDMMESHYKEFIQALISIETGIENEQD
                     LEDLYTYYMRTDSISLLSSDLETSPQKVEMEIEL"
     gene            complement(36859..37425)
                     /locus_tag="VQ862_000645"
     CDS             complement(36859..37425)
                     /locus_tag="VQ862_000645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000013900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3115035.1"
                     /translation="MANSRDYRNPNYTEKIKLQRFFTQLQIAASFFKEHFVGKIMYYE
                     TEIESVELHFSPTNFMHLCGVDYQKGAGSFFDDCLNRHVIIDELKIKKDGTTMQKLQV
                     LGSIEELLGKHVHLTGSGRYLYLEFDYALRTRKQILALTLKETSRKIVPQSLLDLKRK
                     TVFPKGQKVISIYSKHLQTSELFYYLKD"
     gene            37444..37632
                     /locus_tag="VQ862_000646"
     CDS             37444..37632
                     /locus_tag="VQ862_000646"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3115036.1"
                     /translation="MVYRVCKPPSQSVYSGVCHRLALTSKIAIGFRSGVRHRLALMSK
                     ITIRLTMSRLLIYTIYST"
     gene            complement(37663..40476)
                     /locus_tag="VQ862_000647"
     CDS             complement(37663..40476)
                     /locus_tag="VQ862_000647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014713381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HET3115037.1"
                     /translation="MKDKRKIIRARKAFRRSLKDEKKFLKKGKKEVRKQKKDSAVLDE
                     KAWKKEIKEKLEEMREASKERVKQANEDYNHILQNSPPSLLNRKELRDRRLPHARKRL
                     KIAKKQFREAKVEAKEERKEGRKERKTNQKFLYGQESKAKSNFFFQGKSLEELKAKKE
                     VKDAKENLKSTKQAYKSKKVSRKAKTFLYVLGREGGELASENEDLEGYRTLQETIRKG
                     KRYSRLSYNLGKASVKTGQATGRFTKKRLTNTKERYHHFKDGKGWKLAKDNPSSFKNR
                     YRKLKKQGLTSVRNIYQKLKAAFSFFTFAAGNPATWIVGGIVFLLLLMMSFFLGFSSA
                     SLIQQDEFELTKAYTHLTWEDAEHTRTNDKGITYYTKVDDVMGYMNFKFHDYELHKPV
                     HLFSSETYKDYLSTLWHDLNDGEDLKSMQDLYETPKYKLSKDDQEEMKELKEEGVYAS
                     MQELDNPFEGKSNEDSLTMTYRYGYYDLDGKPTLQEYILLEAKAHQAIVAPMDGVVSL
                     DGDNVILTNGKGENESRLTLYSIHNGRAIEGTRVLTGDVIGETPDDTGLKVSYQKYKN
                     KKEKLVYVNPQFYFPKVIQLQTTILPAIGQFGGDEFERAKHIYEFLKSQGASPQAIAA
                     ILGNWSVESSINPKRAEGDYLSPPVGATASSWDDETWLAIGGPAIYSGAYPNILHRGL
                     GLGQWTDTADGSTRHTALLNYAHSKNKKWYDLDLQLDFMLHGDSPYYQSWLKDFFKNT
                     GSAANLAQLFLTYWEGNSGDKLLERQTRATEWYYQIEKGFSQTNGGQAKSDPQSLEGV
                     RGDLYDHSVPGGGDGMAYAYGQCTWGVAARMNQLGLKLKGSNGEKISIINTMGNGQDW
                     VATASSLGGETGSTPRAGAIVSFVGGTHGTPAIYGHVAFVEKVYDDGSFLVSETNYGG
                     NPNYTFRKISQADSAISFAYTTK"
     gene            complement(40488..42845)
                     /locus_tag="VQ862_000648"
     CDS             complement(40488..42845)
                     /locus_tag="VQ862_000648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000824168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HET3115038.1"
                     /translation="MKRKSNTLKKQKTSMTNKKEEVKGKKEEVLPSTANTLSYQALYQ
                     NGLMQVKEDYFSQSYLLGDVNYQTVGLEDKGAIIEKYSDLINSLDDQTNFQLTIFNKR
                     LNLEKFRQSVLYEEKEDGYDTYRKELNRMMNQNLDSGENNFSAVKLISFGRKDSNPKQ
                     AYRSLSQIGEYFKSGFSEIDARFESLAGEDRVNLLADMLRGEHHLPFSYRDLTRSGQT
                     TRHFIAPNLLDFKNKNYLQINDRLLQIVYVRDYGMELGDQFIRDLMQGDLELIVSLHA
                     QSSTKADAMKKLRTKKTLMESQKIGEQQKLARTGIYLEKVGHVLESNIDEAEELLKTM
                     TETGDKLFQTVFLIGIFGQDEEELKQALDTIQQVAGSNDLMIDKLPYMQEAAFNSLLP
                     FGCDFLEGVSRSLLTSNVAVNSPWTSVDLQDRSGKYYGINQISSNIITIDRSLLNTPS
                     GLILGTSGAGKGMATKHEIITTKIKESGENTEIIIVDPEAEYSVIGRAFGGEMIDIAP
                     DSQTYLNVLDLSDENMDEDPVKVKSEFLLSFIGKLLDRKMDGREKSIIDRVTRLTYQS
                     FKEPSLEEWVFVLSQQPEEEAQNLALDMELYVEGSLDIFSHKTNIQTGSNFLIYNVKK
                     LGDELKQIALMVVFDQIWNRVVRNQKLGKKTWIYFDEIQLLLLDKYASDFFFKLWSRV
                     RKYGASPTGITQNVETLLLDPNGRRIIANSEFMILLKQAKNDREELVQLLGLSKELEK
                     YLVNPEKGAGLIKAGSVVVPFKNKIPQGTQLFDIMSTDPDKMASN"
     gene            complement(42796..43155)
                     /locus_tag="VQ862_000649"
     CDS             complement(42796..43155)
                     /locus_tag="VQ862_000649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001097586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PrgI family protein"
                     /protein_id="HET3115039.1"
                     /translation="MNTRVFKDISKYQHRAWLGFTTRQIIFVLPAFIVTIIVLGLNLF
                     FWQFGDWFVYGFVFAFTIPLMLFGVYKPNDLYFEHYLKYRLHFELTVPLRTITGKKGP
                     EHEKKIKYIKETKNFND"
     gene            complement(43209..44063)
                     /locus_tag="VQ862_000650"
     CDS             complement(43209..44063)
                     /locus_tag="VQ862_000650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004263826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TrbL"
                     /protein_id="HET3115040.1"
                     /translation="MNLSLVSPFVYLASEKISAENLFEGFNVDLQSTVDLIKSLSSYN
                     PTVWTYMSSITKSVMQPLGVAILSVVLILEFSKMAKKIANSGGAMTFEALAPMLISYI
                     MVAVVITNTTVIVEAIIGIASHAIEQVASIVAHGGAKYDTLSGLKGSGFIGRMIVGFF
                     ALLIWLVRIVSAAMVNLLVSIRFIQLYLMIPFAPLTIPTFLSDEWKSIGIGYLKNIMV
                     YAVQGVLIFLIVSLVPLFESAGKIAVSNGAGVLQSLAIMFGSLVQAILLIIALVGSQR
                     TARSILGM"
     gene            complement(44080..44322)
                     /locus_tag="VQ862_000651"
     CDS             complement(44080..44322)
                     /locus_tag="VQ862_000651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000627866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3115041.1"
                     /translation="MITHFKGFVYGVDASAMFAQAMSLLQKGLIAVGAFLVVVGIVNL
                     ATNIKDGGPGVRNAILEIVGGVMVGAAGAFVTQISI"
     gene            complement(44343..46220)
                     /locus_tag="VQ862_000652"
     CDS             complement(44343..46220)
                     /locus_tag="VQ862_000652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002883241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretory system conjugative DNA
                     transfer family protein"
                     /protein_id="HET3115042.1"
                     /translation="MYSGKKFLLFSLLGILLGYLFHRLTLLYDSYTGNTLDKWTHLLM
                     EGQDEVLQSPWNVSFTGKSSAFFLLGFVMMLLVYLYLETGKKQYREGVEYGSARFGTL
                     KEKKLFYGKEFSHDTILAQDVRLTLLDKKPPQYDRNKNIAVIGGSGSGKTFRFVKPNL
                     IQMNSSNIVVDPKDHLAEKTGKLFLEHGYQVKVLDLVNMKNSDGFNPFRYIETENDLN
                     RMLTVYFNNTKGSGSRSGPFWDEASMTLVRALASYLVDFYNPPKTREQLIEESRLSQK
                     EYQNLLKRQKKEVEERKKRGRYPSFAEISKLIKHLSKGENQEKSVLEILFENYAKKYG
                     TENFTMRNWADFQNYKDKTLDSVIAVTTAKFALFNIQSVMDLTKRDTLDMKTWGKEKS
                     MVYLVIPDNDSTFRFLSALFFSTVFQTLTRQADIDFKGQLPLHVRVYLDEFANIGEIP
                     DFAEQTSTVRSRNMSLVPILQNIAQLQGLYKEKEAWKTILGNCDSLVYLGGNDEDTFK
                     FMSGLLGKQTIDVRNTSRSFGQTGSGSLSHQKIARDLMTPDEVGNMKRHECLVRIANM
                     PVFKSKKYNSTKHPNWKYLANQESDERWWNYQINPLNQRQENYLDDLRIRDLTFESSL
                     K"
     gene            complement(46220..46708)
                     /locus_tag="VQ862_000653"
     CDS             complement(46220..46708)
                     /locus_tag="VQ862_000653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3115043.1"
                     /translation="MSSEQQERMAVQYAERSLLFTVKSLLKILEWSRRQALAQDSAYK
                     IGVQKLEELLQSPYAIDTINLKKDFLDKPIDIEKFKAFLEKEEIPLAIAWQGDSLHFY
                     AKDRSILDNHLDHLLEKMVNDPEKLADFTMDKSLDDAIDEAKSQITFRQEGAVKQKEM
                     VR"
     gene            complement(46698..>46902)
                     /locus_tag="VQ862_000654"
     CDS             complement(46698..>46902)
                     /locus_tag="VQ862_000654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000869756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3115044.1"
                     /translation="GHLKKDYIEFKRVGIVDGKAVEVTLREPYSRDLLKVVKSIKQRQ
                     KLIAYRYKEGKLLFVKKEASDVL"
BASE COUNT        14003 a         9150 c         8151 g        15598 t
ORIGIN      
        1 tatgaggtgc tttatgatat aatgttctta atgaattttc agaaaggaaa acctcaaatt
       61 gttctacaaa tttctactct tcgacctcga ccacactctt cttgattttg atgctgctga
      121 ggatgtggct ttgacccaac ttctaaaaga agaaggagtt gcggatattc aggcttataa
      181 agattattac gttcctatga acaaggctct ctggaaagac ttggagctga agaaaatcag
      241 taaacaagag ctggttaaca cgcgcttttc tcgtttattt tctcattttg gacaggaaaa
      301 agacggtagt tttcttgccc agcgttacca attttatctc gctcagcagg gacaaacact
      361 atcgggcgct catgatctct tggacagcct cattgagcgt gattataact tgtatgctgc
      421 gacaaatggc attactgcca ttcagacagg acgtttggct caatctggtc tagtacctta
      481 tttcaatcaa gtctttatct cagaacagtt gcaaactcaa aagccggatg ctctctttta
      541 tgaaaagatt ggccagcaaa ttgctggatt tagtaaagaa aagacgctga tgattggaga
      601 ttctctaacc gccgacattc aaggtggcaa taatgcgggg attgacacta tctggtataa
      661 tcctcatcac ctcgaaaatc acacacaagc ccagccgact tacgaagtct attcttacca
      721 agacttgctg gattgtttag ataaaaatat tcttgaaaag atcacatttt aaaggagatt
      781 agctaatgac tacaaaaaaa gctaatatta ctattgaaga gtacattgaa atgtctgaag
      841 ttgattttaa tgaagctgtt aattatgaat ttacatctga cacttgtcaa ttagcaaata
      901 gtatttatca atctcttttt aagttttttg ataagaaaaa tttctctggc gatttaattt
      961 ttacttggaa atctccatca ttagtcaaag aaggggatta tattgggaga agggattcac
     1021 aagtagataa tcttagagta ataggaaata tatttccgaa ttatcttact aatcgaaaat
     1081 atagcctcaa tatgaatcgt aatggctgta tgggagattt tcctcatgac ttttttgata
     1141 tatacctaga tcatgtagca aaatatgcct acgaacaaaa agttaataat attaaagagt
     1201 attatccttt aaaaagagcg attttacacc aagagaatgc attgtatttt cgattttttt
     1261 ctaattttga cgacttttta gaaaaaaatt atttaaagac tatatggcaa gtttctaaag
     1321 aaactccttt ttctgaaatg gattttaata tgtttaaaaa tatttcagaa aagataatct
     1381 tcgaaagagg tagtaaaatg cttaatgatt taaaaagtaa ttataaaaaa tagccagtct
     1441 ttataaactg tattcacgta ttcaaatcgt atatatagtc gatttattaa atctttagat
     1501 aaactgtaaa aagtggtttc catagccact ttttgctata atagaggcag taaaaatgaa
     1561 ggagtcggct atggaacact cgtcttggca tgctttgatt aaggcgcaat tacctgaggg
     1621 ttatttcggg aaaatcaatc agtttatgga gcaggtctat tctcagggga ttatttatcc
     1681 acccaaggaa aaggtttttc aggctctctt gacaacactg cttgaagaag ttaaggtggt
     1741 aattctaggg caagacccct atcacggacc aggtcaagcg cagggcttga gtttttctgt
     1801 acctgactct atcccagctc caccatcctt gcaaaatatc ttgaaagaat tgtcagatga
     1861 tatcggagtt aagaaatctc atgatttgac atcttgggct gagcaaggag tcttgcttct
     1921 taatgcttgt ttgactgttc ctgctggaca ggccaatggt catgctggtc aaatctggga
     1981 gccttttact gatgctgtga ttcaggtggt caatcatcta gatagaccag tcgtttttgt
     2041 actctgggga gcttatgcac gtaagaagaa ggcattagtt accaatcctc atcacttgat
     2101 tatcgaatca gcccatccaa gtcctttgtc ggtttataga ggattttggg gttccaagcc
     2161 cttttccaag gccaatgcat tcttaaaaga gacaggacaa gagccaatcg attggcttag
     2221 ataaggagaa aatatgcctc agttagcgac gatttgctac attgataatg ggaaagaact
     2281 gctcatgctc catcgtaata agaaacccaa tgatgtccat gaagggaaat ggattggtgt
     2341 gggtggtaag ctagagagag gagagacgcc ccaggaatgc gcggcgcgtg aaatccttga
     2401 agaaacaggg ctcaaagcca agccagttct aaaaggtgtc atcacttttc ctgaatttac
     2461 accagattta gactggtaca cctatgtttt taaggtgacg gagtttgagg gcgacttgat
     2521 tgactgcaat gaggggacgc tagaatgggt tccctatgat gaggttttga gcaagccgac
     2581 ttgggaaggt gaccacacct ttgttgagtg gcttttagag gataaaccct tcttttcagc
     2641 caagtttgtt tatgatgggg ataaattgtt ggatacccaa gttgatttct atgaataaag
     2701 gagaaagcag atgctactaa tcaaaaatgg tcgtgtaatg gatcccaagt ctggtttgga
     2761 tcaagtttgt gatgtcttag ttcaagatgg gaaaattatc aaaattgcgc ctgagatcac
     2821 ggaagaagga gcagaaacga ttgatgctac tggtcttgtg gttgctcctg gtttggtcga
     2881 tattcatgtg catttccgtg aacctggtca aacacataaa gaagacattc atactggtgc
     2941 cctggcagcc gctgcaggtg gttttactac tgtcgtcatg atggctaata ccagtccaac
     3001 catttcagac gtggagactt tgcaagcagt tctccagtca gctgccaaag agaagattaa
     3061 tgtcaagaca gttgcgacca ttactaaaaa ctttaatggt aaaaacttga ctgactttaa
     3121 ggcgctctta gaagctggtg cggctggttt ctctgatgac ggtattccgc ttgagagcag
     3181 taagattgtc aaggaagcca tggaggaagc caaaaaactc aataccttta tcagccttca
     3241 tgaggaagat ccaggtttga acggtgttct tggctttaat gaaaatattg ctagagaaca
     3301 tttccatatc tgcggtgcta ctggggtggc tgagtacgct atgatggcgc gtgatgtcat
     3361 gattgcctat gcaactaaag cccatgttca catccagcat ttgtctaagg aagaaagtgt
     3421 taaagtagtg gagtttgctc aggggttagg tgcagaagtc acagcagaag tagcgccaca
     3481 gcatttctct aagacagaag cacttttttt aacacaaggt agcaatgcta agatgaatcc
     3541 accgcttcgt ttggaatcag accgtcgtgc cgttatcgaa ggtctcaaat caggtgtcat
     3601 cacagttatt gcgactgacc acgcccctca tcatgtagat gaaaaaaatg ttgaggatat
     3661 taccaaagcg ccatctggta tgactggctt agaaacatcc ctgtctctca gcttgaccta
     3721 tttagtagaa gctggtgagt tgagcttgat ggaattactt gaaaaaatga catacaaccc
     3781 agccaagctt tacaactttg aagcaggtta cttggctgag aatggtccag cagatatcac
     3841 tatttttgat gccaaggctg accgccttgt ggactcccat tttgcttcca aagcagctaa
     3901 ttcaccattc atcggtgaaa ccttaaaagg gcaggttaaa tataccatct gtaagggaca
     3961 aatcgtctat caagcttgat aggagttaga atatgaatta ttttcgaaaa cgtagggaga
     4021 gacaagcgaa atctaatagt ggaatttact gtcccgcagc taatcgttcc aaaattcaat
     4081 atgaaactaa agaaaaagct gaccatgcgg ttcaatatga taacggaggt ttagttagaa
     4141 gctattattg tcgtacatgt gcgtgttggc atactacttc aaaatctaat aaacctccgc
     4201 taagtttgaa aaactatggt ctgaaactct ttggtttaga taaatcagaa tagaaagaga
     4261 agtatgtata agacaaagtg tttacgagag aagttagtat tatttttaaa aattttcttc
     4321 ccaatcctga tttaccaatt tgccaattat tctgcctctt ttgttgatac tgcaatgaca
     4381 ggtcaataca acactatgga cttggctggt gtatctatgg caaccagtat ctggaatcct
     4441 ttctttacat ttctaacagg gattgtgtca gccttggtgc ctatcattgg tcaccatctt
     4501 ggtcgaggaa aaaaggaaga agttgcgtct gatttttacc aatttattta tttggccttg
     4561 ggcctatctg tggtattgct ggggatggta ctttttttgg caccaacaat cttgaatcat
     4621 attgggttag aagcagcagt agcggcagta gcggttcgct atctttggtt tttatctatc
     4681 gggattatcc ccttgttgct ctttagcgtc attcgttcct tgctggattc gctgggcttg
     4741 accaaactgt ccatgtacct catgcttttg ttactccctc tcaatagcgg atttaactat
     4801 ctcttgattt acggtgcctt tggtgttcca gaactgggag gggctggtgc tggtttagga
     4861 acatccttgg cctactgggt cttgcttggg atttctgttc tggttttatt taaacaggag
     4921 aagctcaaag ccttacacct tgagaaacga attccactta atatggataa aattaaggaa
     4981 ggagttcgtt taggtctgcc tattggggga actgtcttcg cggaagtggc tatcttttca
     5041 gtggttggct tgattatggc taagttttcg tccttgatta tagctagtca ccagtcagct
     5101 atgaactttt caagtcttat gtacgccttt cctatgagta tctcatcggc tatggctatt
     5161 gtcgtttcct atgaagtggg agccaagcga tttgatgatg cgaaaaccta tattggtcta
     5221 ggaagatgga ctgccctcat ttttgcggcc ttcaccttaa ccttccttta catttttagg
     5281 ggaaatgtgg ccagtcttta tggtaacgac ccaaaattta tcgatttgac agtgcgtttt
     5341 ttaacttata gtcttttctt ccagttagca gatacctttg cggcgccgct tcagggaatt
     5401 ttgcgggggt ataaggatac agttattcct ttttaccttg gtttgcttgg ttattggggc
     5461 gtagcaatcc ctgtggctac gctatttgat tctctaacag attttggagc ttattcttac
     5521 tggatcggct tgattattag tttgattgtg agtggggcgc tctaccgttg gcgtttaact
     5581 gtgattatga agagatttga atctttagca aaatccaaac gctaaaaagt ttgtgaaaaa
     5641 atattcttga taagaaaatc ccttgttttc acgggatttt cttttttatt ttgtgaaatt
     5701 tcttttagaa aaactttgac agtatttgcc aaaaacggta aaatagtaag gtaagaagaa
     5761 agttagaaag gcaagaagat gtcaacttta gataaaaatc ttttgctaga aatgttccgt
     5821 aagatggaag aaatccgtcg catggactta aaaattgcac aattagtaaa gaaagggaaa
     5881 gtgccaggaa tgacgcactt ttctgttggt gaagaggcag ctaacgtggg ggctatgtta
     5941 gctctcaatc cagatgatct gattacctca aaccaccgtg gacacgggca agctattgct
     6001 aaagggattg acctcaacgg aatgatggct gaaatccttg gtaaatacac tggaacctgt
     6061 aaagggaaag gtggatctat gcatatcgct gaccttgatg ctgggaacct tggtgccaat
     6121 ggtattgtag gtggtggtat ggggatcgct gtcggtgcag ccctcagtca gcaaatgcaa
     6181 aataccggta aaatcgttgt ctgcttcttt ggagatggtg cgaccaatga aggtgttttc
     6241 cacgaagcag tgaacatggc ttctatctgg aacctgccag tcattttcta ttgcattaac
     6301 aacggttacg gtatctctgc ggatatcaag aaaatgacca atatagaaca tatccatcaa
     6361 cgtagcgccg cttatggaat tcctggaatg ttcatcgaag atggtaacaa tgtcatcgat
     6421 gtctatgaag gatttcagaa agctgtggac catgttcgca gtggcaatgg tccagtcttg
     6481 attgaaagtg taacttatcg ctggctcggt cactcatcat ctgaccctgg taaatatcgt
     6541 acgcgtgaag aagtggaatt gtggaaacaa aaagatccaa tcgaaaacct ccgcaattac
     6601 cttattgaaa ataacattgc aagtgccgaa gaattggaag aaatccaagc gcaagtaaag
     6661 gaagcagtag aagcttctgt taaatttgca gaggaaagcc cattcccacc gcttgaatca
     6721 gcctttgaag atatttacgc agactaagga gaaagagata aaatggaaac aaaaacaatg
     6781 tccttccgtg acaccattat ccttgctatg tctgaggaaa tgcgtcgcga tgaaaatgtg
     6841 ttcttgatgg gagaagacgt cggtgtcttc ggaggagact tcggtacttc tgttggaatg
     6901 cttgaagaat ttggtccaga acgcgtccgt gactgtccga tttctgaagc tgccatctct
     6961 ggagcagcag caggagcagc catgacagga cttcgtccaa tcgtcgatat gaccttcatg
     7021 gacttctctg ttattgccat ggacaatatc gtcaaccaag ctgctaaaac acgttacatg
     7081 tttggtggta aaggtcaggt tccaatgact gttcgttgtg cagctggtaa cggagttggc
     7141 tctgccgccc agcactcaca atctctagag tcttggttta ctcacattcc aggacttaag
     7201 gttgtggcac ctggaacacc tgcggacatg aaaggcctgc ttaagtcttc tatccgtgat
     7261 aaaaacccag ttattatact tgagtacaag tcagaattta accaaaaagg ggaagtgcca
     7321 gttgatccag actacacaat tccacttggg gttggtgaaa tcaaacgcca aggaacggat
     7381 gtaacagttg ttacttatgg aaaaatgctt cgccgtgtgg ttcaagctgc tgaagaatta
     7441 gcagaagaag gaatttcagt tgaaattgtt gacccacgta cccttgttcc gcttgataag
     7501 gatatcatca taaactcagt gaagaagact ggtaaggttg ttctggtcaa cgatgcccac
     7561 aaaacaagtg gctatatcgg tgaaatttca gctattattt cagaatcaga agcatttgac
     7621 tatctagatg caccaattcg ccgttgtgca ggagaagatg tgccgatgcc ttatgcacaa
     7681 aacctagaaa atgcaatgat tccaacagtt gaaagtatca aagatgcaat ccgaaaaact
     7741 tataacaaag aatagagtta cataagataa gttatgtaaa taaaataaag ctgacgagaa
     7801 actttgtatc ttttaggtgc agagctcttc gtcattaata tcttagatta gagcacgggc
     7861 taaaagctcg gaaaaaagat aaatctcctt ggcttcatcg aagccatcgt cgatttccta
     7921 tttttcagtc gcttttgacg ccctttgtat cataaataga attggagagg tcatggctga
     7981 tgacaagcta agagcgactc ctgcagctag aaagttagcg gatgatttag ggataaacct
     8041 ctacgacgtt tctggctcag gtgcaaacgg tcgtgtccac aaagaagacg tggaaactta
     8101 taaagacaca aacgtggttc gcatttcgcc acttgcaaaa cgaattgccc tcgaacataa
     8161 cattgcttgg caggaaatcc aaggaaccgg tcatcgtggt aaaatcatga agaaggatgt
     8221 tttggccctg cttcctgaaa atatcgaaaa cgatagcatc aaatctcctg ctcagattga
     8281 aaaagtggaa gaagtccctg ataacgtaac accatatggt gaaatcgagc gtattccaat
     8341 gacaccaatg cgtaaggtta ttgcccaacg catggttgaa tcttacttga ctgcgccaac
     8401 cttcaccctc aactatgaag ttgatatgac tgaaatgttg gctcttcgta agaaggttct
     8461 tgagccaatc atggaagcaa ctgggaagaa gactactgta acagaccttc tttcgcttgc
     8521 agttgttaag actcttatga aacacccata catcaacgct tcattgacag aagatggcaa
     8581 gactattatc actcacaact atgtcaatct tgccatggca gttgggatgg ataatggatt
     8641 gatgacacct gttgtttaca atgctgagaa aatgagtctt tcagaactgg ttgtagcctt
     8701 taaggatgtt attggccgta ccttggatgg taaattggct ccaagtgagt tacaaaattc
     8761 aacattcaca atcagtaatt tgggaatgtt tggtgttcag tcctttggtc cgattattaa
     8821 ccaacccaac tcagctatcc ttggtgtcag ttcgacaatc gagaagccag ttgtcgtcaa
     8881 tggtgaaatt gtgattcgcc caatcatgag tttaggatta accattgacc accgtgtcgt
     8941 agatggtatg gctggtgcta agtttatgaa ggacttgaaa gagttgattg aaacgccaat
     9001 ctcaatgtta atttaagagc aagagtattc atttttaaga tatagataaa ggaaggaaga
     9061 catggcctta gaagtaatta tgccaaaagc cggcgtggat atgacagaag gacaaatcgt
     9121 ccaatggaat aaaaaagtcg gagaatttgt aaaagaagga gaaatccttt tggaaatcat
     9181 gactgataaa gtcagcatgg aattggaagc cgaagaagat gggtacttga ttgccattct
     9241 caaaggagat ggtgaaactg tccctgtaac ggaagttatc ggttaccttg gtgaagaaag
     9301 ggaaaacatc ccaacagctg gagcagcatc gccagaagct agctctgtac ctgtagcaag
     9361 tacctcaaac gatgatgata agagcgatga tgcttttgat atcgttgtga ttggtggagg
     9421 tcctgctggt tatgttgcag ccattaaagc tgcccaattc ggcggtaagg ttgcccttgt
     9481 tgagaaatct gaacttggtg gaacctgctt aaaccgtgga tgtattccaa ccaagaccta
     9541 ccttcataac gctgaaatta ttgaaaatat cggtcatgct gcaaatcgtg gtatcgtgat
     9601 tgaaaatcct aacttcactg ttgatatgga aaaactttta gaaactaaat ctaaagttgt
     9661 taatactctt gttggtggtg ttgcaggact tcttcgtagc tacggagtta ctgttcataa
     9721 aggaattggt acaatcacta aagacaagaa cgtcttggta aatggctctg aattgcttga
     9781 aaccaagaaa atcattcttg ctggtggttc aaaagtcagc aagatcaacg tccctggtat
     9841 ggaatctcca cttgtcatga ctagtgatga cattcttgaa atgaacgaag tgccagaaag
     9901 ccttgttatc atcggtggtg gagttgtcgg tatcgaactc ggtcaggcct tcatgacatt
     9961 tggttcaaaa gtgactgtta tcgaaatgat ggactgtata gttccagcta tggatgcgga
    10021 agtttctaag aaccttcgct tgatccttga gcgtaaagga atgaccatct tgactggtac
    10081 taaactgcaa gaaatcattg aggaaaatgg tcaacttcgt atcaaggttg aaggaaaaga
    10141 cgatatcatc gcaagcaaag ctcttctttc aattggtcgt atgccagacc ttgaaggtat
    10201 tggagaggtt gagtttgaat tggatcgtgg ttgtatcaag gtcaatgaat acatggaaac
    10261 ttcagttcca ggcatttatg caccaggtga catcaacggt actaagatgt tggctcacgc
    10321 agctttccgc atgggtgaag tttccgctga aaatgccctt aaaggaaatc atgcaattgc
    10381 caaattgaat ttgactcctg cagccatcta cactctccct gaagtagcag cagtaggttt
    10441 gacagaagaa caagcccgtg agaaatacga tgttgccatc ggtaagttta actttgctgc
    10501 taacggtcgt gctattgcat ctgacgctgc tcaaggtttc gtaaaagtta tcgttgataa
    10561 gaaatacgga gaaatccttg gtgtacacat tattggtcct gcagccgcag aattaataaa
    10621 cgaagcatca agcatcatcg aaatggaaat cactgttgag gaaatgctga agaccatcca
    10681 cgggcaccca acttactctg aagtgatgta cgaagcgttt gcagatgttc taggaatggc
    10741 catccattca cctaagaaaa aataaaacga agatagatta gactggaagg ttatttccag
    10801 tttctatcat ataaagtaaa gggatatcat gaaatacatt atcaatcatt caaatgacac
    10861 tgcttttaat attgccttgg aagaatacgc ctttaaacac cttttggatg aggatcaaat
    10921 cttcctactt tggattaaca agccatctat cattgttggt cgtcaccaga acactatcga
    10981 agaaatcaac cgtgattatg ttcgtgaaaa tggtattgag gtagttcgcc gtattagtgg
    11041 tggtggagct gtttaccacg atttaaataa cctcaactac acgatcatct ccaaagaaga
    11101 tgaaaataag gcatttgact tcaagagctt ctcaactccg gttatcaata ccctggctca
    11161 acttggggtt aaagctgagt tcacaggtcg taatgacctt gagattgatg gtaagaagtt
    11221 ctgtggcaat gcccaagcct atatcaacgg ccgtatcatg caccacggtt gcttgctctt
    11281 tgacgttgat ttgtcagtcc tcgcaaatgc ccttaaggtt tcaaaagata aatttgaatc
    11341 aaaaggtgtg aaatccgtcc gtgcccgtgt aaccaatatt atcaatgaat taccaaaaaa
    11401 aatcacagtc gaaaaattcc gtgatttact cttggaatac atgaaaaaag agtacccaga
    11461 gatgactgaa tacgtctttt cagaagaaga attggccgaa atcaatcgca tcaaggatac
    11521 taagtttgga acttgggact ggaactatgg taaatcacct gaatttaacg tccgtcgtgg
    11581 aaccaaattc actagtggta aggttgaagt ctttgctaac gttactgaat caaaaatcca
    11641 agacatcaag atttatggtg acttctttgg tattgaagac gttgctgcag tagaagatgt
    11701 ccttcgtggg gtgaaatacg aacgcgaaga tgttcttaag gcgctaaaaa ccattgatat
    11761 cacacgctac ttcgctggta ttagccgtga agaaatcgct gaagcggtag ttggataaat
    11821 caaaaagaag ttggccaact aaccaacttc tttttttgat atttatttac ataatttaaa
    11881 atacgtaaaa ttataaacta tctagagcat tcttttgttc atcattaaca atatgggtat
    11941 agaggtcagt gacttgtgtg ctggcatgtc ctagttggtg actgactaaa acttgtgatt
    12001 tagtcgcatc atagagccta gttgctagcg tatggcgcag tttatggggt gttacacgca
    12061 ctttaaaatc ctctgagtat ttagcaacca ttttctcaac gctagaagca tcgatacgat
    12121 taggaacacc tctgtagaga gttaaaaaaa gggctgtatc tgttttttcc gttttatagc
    12181 gttgattccg aatggccaga taattctcta aataaggttt agcaaaagca gcgacattga
    12241 ctgagtcacg tttgccacct tttcgagtaa catcaataac catcattttt agattgagat
    12301 ctcttagatc tagattaaca gcttcagata agcgaacacc agatgccaag agaagggcaa
    12361 taatggctaa atctcgttct ttatttttgt tgaatgatga gagagctcga tttgaaagct
    12421 gttgtgggtg ctcttgatcg atataagtta gaaaacctgc tgtttcatca cctagaaaga
    12481 gtttttgctt gatattttca gctctggcag caagggtttc tttctttttc ttggttgaaa
    12541 cttttttcat tacattacga tagaaataag gttccccctg atcattttca acctcctcgg
    12601 ttagatactt gtaaagacta gaaagtgctg ataaggttcg attgatagtt gtctgtgaaa
    12661 caccttgttt tgttgtatta gcattcagca agggacgttc acgtagataa aggataaagg
    12721 attccatgtc tttcttagac atattttcca aaactgataa aggaatatcg gatattttat
    12781 cagcgtttga aataccagac tccaaaaccc agctgaaaaa tcggtcatat tccttaaggt
    12841 attcgtacag ggttgtaaaa ctgtagggca cagccagttt agattggtag tattccagaa
    12901 cataccaggg catgagttgt tttagtttgt cgattcgttc cagtaaaatc tcacgtttca
    12961 tgtattttct ccataattaa gtatactagt agtatagcat agacttgtat atttttcaag
    13021 aaaattatag tttttcagaa agatgttata ggagtttttc aaagtgataa aaagacttag
    13081 acctacaaac aaaacagaat aaggaaaata ataaaaatct cacccactaa acttctgtta
    13141 atactacata gctagaaatt gatttgattg tcctgattgt tttatcctat ttctatttca
    13201 tttcactata taattgctat tgttttcttt ttcatgattt taatcttact gtacagattt
    13261 gatacagtaa actcctttct agctttatgc tttatcattt ctaacttaat tatagtctta
    13321 tttttaataa agttcaatta tttatatgta aaattcctca tcagtaaaaa ataaccgatc
    13381 tcatttctga gaatcggttt tctaaataaa tcaaaccgat catttacata acataaatta
    13441 tgtaaatgat catactacaa caacaaatct ttgacttttc caatttcact ttttggaata
    13501 accaggtgaa tcatatcacc cagatacatt ctggttgagc cgttaactgt ttggctcttg
    13561 ccattatgga cttgagttgt gatgaggacg ttgtgtggta agttgagttc atgaacttgt
    13621 ttcccagcaa ttttatcaga aactggtatt tcgataagtg taacttctcc ttcgctagat
    13681 acttcttctg gaagcatttt ttccagcatg gcttcataga ctggcgtacc tttgagcaaa
    13741 tccatgataa tataagaaac aagagtgaca agaccaagtg gcataaggtt gcgaatatct
    13801 cctaccatct cagttacgag gatcatagcg gttaagggag cttttgatat ggctccaaaa
    13861 tagccactca ttcctagaat gacaaatata gggaattgct cttgactgac aagtccaaga
    13921 ttgacacaga taacaccaac taaggcacca agcaaagaac caagagctaa aatggggagg
    13981 aaaattcctc ctggcagtcc acttccatag ctaatcatac tccaaataaa gcggattaaa
    14041 aagtaagcta ataaaacttg gaaactaaaa ttttgttcag ttaaagaaag gacaagctga
    14101 tttccgccac caatgatttg aggtaagaag attccgactg gtatgataag gataaaagcc
    14161 aagatgggat aataagccct atccaaatgg attttttgac caatcaagtc ataaactctt
    14221 ccaacgttta atacagcttt ctcatagaga aaacctgaaa atccaaggaa aattcccatg
    14281 acgagatata tccaatactg gtctagggtc atgggaggaa tgttatctgg catatccaat
    14341 actggtgtca aaccgaacat gagtagagac acaaagtttg ctacgatgct ggctgctaga
    14401 gttgagaccc agaaaaagcg cgaaaaatgg tgatagactt cttctacaac aaagagaagt
    14461 gctgcaatag gagcattaaa ggctgcggct aaacctgctg cagctccact ggcaatcaag
    14521 gaacgttcct ctactggact ggatttgagc cacttggcaa ttcctttacc accaactgct
    14581 ccaagttgaa tgctgggtcc ctctcgaccc agcatgagtc cactggcaat agcaagaata
    14641 cctagcacat attttttcca aagaatgccc caccagttga gggacatgag gcctttcagt
    14701 tcggcttcga cttgaggaat tcctgagcct ttaatatctt tttctgaccg tgttagtttg
    14761 gcactgagcc aacagatgag tatataaaac aaaaccagta caaaaagatt gcgcactaag
    14821 tacccttgat cttgataaac tccttgtatc aggtggaagc ccttttcaat taagaaacga
    14881 aaggatccga cgataattcc aacgatgagg ccgacaatga ttcctcgacc aacttgggat
    14941 agtatagtgc tggatgcaaa ggcgaattct ttcttagaac ggactatttc cgactgttcc
    15001 tccatggtat ttcctttcaa ttaactttct tttttaccta aaaccagtga tttaacgggt
    15061 tcaaagctgg ttcggtgaat tggggtaact cctagttttg tgaggccttc cagatgttta
    15121 gctgtgccat atcctgcatt agtagcgaaa tcatagccag agaactgctg atcgtattct
    15181 ttcatcaatt catcacgtgt taccttggct actatagatg ctgctgcgat agagagggag
    15241 ttggcatctc ctttgataat ggaggtttgt gaaatgggca agtccagttt catggcatca
    15301 atcaaaaggt gctctggttg agggctgagc tgggagattg cttcttgcat ggctagtttg
    15361 gttgcttcat agatgttgac ttggtcgatg acctgattat ctatgatacc aattccaatc
    15421 gacaaggctt ggtcttgaac ggcttggaaa atctccagat gtttcttttt aggaattttc
    15481 ttgctgtcgt tgagaccttt aatcttacaa tttttaggta aaataacggc cgcagcgact
    15541 acaggaccag caagaggacc acgaccaacc tcatcaatac ctgcaattaa ggtcaatcct
    15601 tgcttataaa gttctttttc ataagaaagc atggattcca agcgcaaatt ttcatctaat
    15661 tcagcttgaa tggctctttt acgcttgctg atttcctttt gaactcctga gcgattatcc
    15721 ttttcaagct ctaaaaaaat agggctttct aactccttga ctgtcacaag gagttctttg
    15781 atttctttaa tcgttgccat cgaggtcttc caatgtatct aaggtatagt taccgagttt
    15841 gccatcacgg acttccttca cgaagagact gtaaaaacgg tcatagtcat cacggaaacc
    15901 gagggcgcgg gtcatatcca taataatcac aggcgcttct tcttcaattt tcatttgttt
    15961 gaagcgttca gccagctttt ctggataatg ttctttgaaa taattgatac caaaaatggt
    16021 aacctcatcc ataggaagca actgatcctt gatagctcca gtcaatgcca acttaagtgc
    16081 aacagtttca tcctcaaact taggccagag aatccccggt gtatccaaga tttccagatc
    16141 tttattggtt ttaagccatt gttgaccttt tgtgacccct ggcttgtttc caacaacagc
    16201 aatcttttta ccagccaaac ggttcatcag agttgattta ccagcgtttg gaatcccaat
    16261 aatcatggta cgcaaggttt caatctgaat cccacgttct ttctggcgag caatcttatc
    16321 agccatgagc ttcttggccg catctgttac aacttttaca gtcacttgct ctttggagtt
    16381 gatagctagc gtctggattc cttgtgattc aaaatactga cgccattcct tggtcattgc
    16441 tggatcagcc aagtcggcct tgtttaaaat caagagtttt ggtttatcac caacaatctt
    16501 ggtcaacata ggattttgac tagatagagg caagcgtgca tctactaaaa tcgtcacaaa
    16561 atcaacaaat tttaaatttt cctgcacctg tcgacgcgct ttagacatgt gaccaggaaa
    16621 ccattgaata gtagccattg agtttttttc ctttcatagc aagggtttag agcccctatt
    16681 ttattttact attgtctaaa caccaagcga acaccaaaac taccatgcaa tggaaaaacc
    16741 tctgatttga ttctcacttg atttcacaat ctttatatca aactgtgggt ggtatttgac
    16801 aatatctttt ttgattttta atagtaaatt cgaaataata tttttaggtg agtaacgtgg
    16861 actaagatgt aacaagtctt tgaactcatc gacactaaat tctactttat tgctattatc
    16921 actagtttca atgaattttt caattattct ggaatattta caggtataac ttttcaattc
    16981 ttcaaaatgg aaattgtgat tttctacaaa ttgatttaag gcttttacag tattttcttg
    17041 tgaacgattt atattatgtg tatagcccat tgttgtctca aagttagcgt gtcctactct
    17101 agtcataata tctttcactg ctatgtgcat ctcattactt tgaaggtaac taatatgcat
    17161 atgcctaaac gaatggggag taacatgttt tacccactta aaaccatagt cacttaaaca
    17221 atttgtcaat aattttcctt ctattcgttt caaaatttga cgaaaagtgc ttgatgttat
    17281 tggagagccg tattctgttc taaatacact ttcagaatgt gtaaaagcag gacagggatg
    17341 tttctccata taagcatcaa actctttatt tctctgtatt gtccttttaa tagcttcgct
    17401 tgcagcttca ggcaaagcta cttctctaat tgaattgagt gttttagttg tatcaaagtg
    17461 aaattgttca acttttaaac aatgatattg aagtgcctta tcaatatgca agattccttt
    17521 ttcaaaatca atatctgatg gtaaaaatgc tgcttcacta attcgaatac ctgtaagcaa
    17581 caatactata gcaagatcat aatagtttgc atttctgcat tggcttaata catcaaaaaa
    17641 tgcgtgtaat tcatggattt ctagaaattt agaatcatgt ctttcttttg ctttacgcct
    17701 tttctctagt gaaatatcta gttttaccgc agtcatagga gagaacttaa tgacattata
    17761 taacacacca tgattaaaaa tcttattaca agtacttttt atatgagtca ttgttgaagg
    17821 tgatgcatca tatatttcta aatatttatt gagacttttt ttcatcagaa gtggagtaat
    17881 cctgtctaat aaaaaatcat ctcctataat tttcccaaga cgcttcatca ccagtagttc
    17941 tctctgaatt gtttgtggtt taacagagac acaccaagtc tgaaaccaat tttcttttaa
    18001 ctctccaaat gttgtaatca gttcagggct aaactgactt tcaaatgaag tagttagtct
    18061 atctatctta tcaagaacct ctctttcagc ttgtttcctc gccctactag tattcttagt
    18121 ataacttaca gttactgatt tccactttcc tgttagtgga tctttgtact tttcaaccac
    18181 ttgatataag ggttgccctt ttgaatttgt tttagttaca taatacataa tttaattcct
    18241 cttaactctt aaaaagaaat aaatcattgt tgtatagaat aaataactac cctatattat
    18301 accatgactt ccttattttg tccgcttttg cttccatctt aagaaacttt caaatccttc
    18361 tagattaatg aaaacaagtt tatgggttgg gttaattaca tacatggaaa atgttctgtt
    18421 ttctcgcatt tctttaatcc atctgttcaa tgtatattga tttaaaccat cccatctttt
    18481 tagaattcct ttcttatcgg cccattctgc aatggaattt tcgacagata tatattttat
    18541 attcatgtca tcatccttcc taaaaaatat tttcacctcc atggcatgac tgatgaagtc
    18601 atcataagaa tttcacttgc tgctctttta cggtggcagc ctgaacggtc agaagtatca
    18661 ttgtatatca tttgtatcat ggcatataaa gtatcgctct attttattga tggttttaat
    18721 atcgctctta tcatggcgag ccattcaaaa ctgctccaca aatgaggaaa gtaccatttt
    18781 ggactattca attgtcaatg tgctttctta acctactact ttttggagta atggtcttct
    18841 ttattatcca ctcgacctac aaggtagtct agactcacct tataaaaatc tgcaagtttg
    18901 ataaggtcat ttatagagat tagcctgcta ccagcttcca ttttagaata agatgatctt
    18961 gtacaattca aaacgatttt cgcaatatat tcttgtgtca aatcatcatc ttcacgtaaa
    19021 tctctaatcc ttttcaacat ttgttgtctc ctaaaacaag tataatatag ttattttctt
    19081 atttttaaat atgtgacaaa ttggcacatg aaactattct atatatactt tttaggaaac
    19141 tgtttactct aaatgtatct cattttcctt aatagatttc gtattttgtt ttttcttata
    19201 tttctttatt gttttattaa acatttcaaa taaatttatt gcttctctat gttgttcctt
    19261 cagtgtttca atctttcctt tatatatgta taaatccttc tctattgtat ctactgaact
    19321 tttaccttga atactatttt ctaaattgct agaactattt gtcgcatcat tcaacaatac
    19381 ttcttctaaa ttactcaaat catcaatttt attttgaacg tggtcaatca tattctctag
    19441 atatgatatt tgggcaatga aatccttggt tatatcttca aaagcattct gactattttc
    19501 tgcagataca agaaaatcta attgttctat tttttcttta attttgctaa gaggaattct
    19561 tctatacata tactgcggtt catactgaag attaaattgc ctaatcaaag ttttaccttt
    19621 cataaagcga tttttttctg ttgaatcttt atgatataca tagtaagaac tagtttctct
    19681 gagaaatatt ttaacttttt cttcttccat attgatttga atatttggta caaaaataag
    19741 tccttcttgt cggataccaa actgtacctt aatgtaaatt ccatcgtcta ctacttcttc
    19801 tatttgatta agattcaact ctacttcaaa ctcatgaact gcatccctat ttctcttgaa
    19861 atcttgatag gatttccata ccacctcttc tgtcggcaac tctttttctt taattagctt
    19921 ttcttcattg taaagttcaa ctaaattttt attatctaag acaacagttt catttttgtt
    19981 attaaaatag ttttgaaaat aactaacact ataccgatta gcttttacca attcctgctc
    20041 tgaaatctta atctcatcaa attcaaattg aacatgtttt tctttcggaa ttatttttaa
    20101 tccaaaaaat tctgctcgtt gaatcaattc attcatattc ttcattttcg gaagtaaaaa
    20161 ttctaagata tttatgattt ccctttgaac aaactttttc ttaaaataag tttcattata
    20221 aggttgtttt ctactcaatt tactatcacg tacgacttgt ttcatatttg aatcagtcat
    20281 aaaaaaagta acatgcttgt gtctaaaatc aattttcaaa tgtaaagctt ttgctttttt
    20341 cttgaaatct tcaaaatttt tcgagttctc gattagaaaa tatactcgtt gttttatttc
    20401 atatttgtaa tttgttttgc gataaacttc atactgacga tgcgaataac gattttctat
    20461 aatttttgcc cctgcaattt ttgaaagacg atcagaaacc attcgtagat tacgttctga
    20521 cttataatcc catagaaact ttttatcaga attctgatca attgaattta ggatgatgtg
    20581 attgtggata tgatctttat ccatatgagt tgctacgata aaacgaaatc tacctcctgt
    20641 caactcttta actgtctcat aaccaatctg attgatttgt tcgggagtga ggtggtcatc
    20701 tggagaaaag gactgaatga tgtgatgaga atgaattttt cgttgattta cttctcgcct
    20761 atcatgacga aattcataaa gagtatcatt acttaaaaaa ttatcattgt acatcttcac
    20821 tagttcttca taactaggaa aatctaaata atttctcatt ccaaaatctg aaactagtgt
    20881 taggtttttt gttttacttg gattcaaaat atatttgatt agtttactac gataattttt
    20941 tccatgaatc gcaaagtgtt tagtgatgac cataaaattt cctcaatttt tcagattgaa
    21001 taagaaaatc tttctccact tctactatta actcttctat accttttctc aactcattta
    21061 attcaacttc cgttattaaa ttagaataat ttatgctcct agctatttga ttaatattat
    21121 ttcctattcg ttttaattca aaaatcaaat cttgataact atttgtatca atggtgataa
    21181 aattcatacc aggatctagt agagttcgtc tagcatattc tgagaacgat aagcagttac
    21241 tttttgagat attttcattc aatttgacta attctaggtc agataaaaag acctttttta
    21301 aatttgttct atatcggtgc tccactctac tacctcatgt atttgttacg aaaatcttca
    21361 ctaagaggac ctgttttttc tacctcttta attaattcct gaatacaagt taacaaaata
    21421 gaaacatgtt cgtgagtaac ctgatgattt gttttagcaa ttatgaatac ttcatgaaca
    21481 tcacggctaa tttgttccaa cttttgtttt ttccaaaggt tgaaccattt ttccatctgt
    21541 ttttgtccat cagataatag taagctttta cggagaaaat cagaaaaatt atcctctcct
    21601 ttctctctca ttaaatctag tatttgtttt tcttccgttt ctgttaagcg aaattgtttc
    21661 cgaatactac gtatatctct tttcatatga tttatcctct ctcatagata cttgtactga
    21721 caatgtaagc ttacagacac tgtcagtacg ttttacaaaa tagattcaac atttttgtaa
    21781 ggctttgcga gctcagatat tgtgtccaca atatcccaaa aatcatatcg cctgccattt
    21841 caaacctcac ggttcaaaaa acaaacgata tgacaatgtg gtggctccgc ccccaaaccc
    21901 ccaagataaa tctaaattaa aaaaagtata acaaatactt tttgataaaa ttatcacaga
    21961 aaaaagagcc ctgtcggact cttacaaatt aaaacaatgt ctctgatatt catactgtct
    22021 aataccacta ctgtctttgt tcatcttgat agaaaaaaca aagtaatgat cacgaccgtc
    22081 taaagattta cttttgttaa gtttaaaata atgtttttga gacatagcca ttgtgcgtaa
    22141 aatatcatct gtgataaatg ttaatggtat atctaaagct gaatacttgt aaaaatctga
    22201 ctcaaactgt aaataagaat ctgaaaaata atctagctgt aatttatcat catataattc
    22261 tttacgattc atgtaattcc tccccttcta tctgtatatc gagtatatct tcccatttta
    22321 atcgaagaaa accagtgtct gattttatag atataaactc ttttccaatc tctttaacaa
    22381 tacctgatac tacttttctt tgattagaaa acttaaaaac aaaagttgca gggaatacat
    22441 tcgtataaag ttgacgaaca aatagaactt tctcttccaa tgatagggaa atggagatat
    22501 cttctttatt tttttctgcc caaagagaac tggaatgttc tgataaaaag aagcccatcc
    22561 acttagccat gccacgatcc tgatatactc gggcagactc aaaaggtaaa taagaacgat
    22621 tcatcatttt agtccatcta atcctccagc tgaatgacca ccaatgagtt tgcttctagc
    22681 aattgttcta gaagcttgat ctagggcatt acctttcaat agtgaagtga atccaaattc
    22741 tgttcgaata gcatcgattg cggactggag cctttcttct ttttctattt tctcaatatc
    22801 atcaaataat gaaatcaatc caaaggattc atccactaaa ccagaatagt taaccgcaac
    22861 attcctgata gctcctgaag tatatttagt gtgaaataac tttaaaacgt agtttgtcag
    22921 tagtgctgtt tgattagttg gttcaatttt catttgagta ttgatagaac gcttttgttc
    22981 cactttagag tagcctagat gtatagaaac tactgttgct tttttaccag atcttctcaa
    23041 tctaactgca acttgttctg ccatctcacg aagtatgatc tcaatatctc tttgtttaat
    23101 ataatctttt ggtaaaactt gagagttccc tatccctttt gactttggct tataaggttt
    23161 atgaacgttg ctttcgtcaa tcccattggc atgaaaccat aactctagtc ccataatccc
    23221 aagctctttt ttaatcaagt caggattagc ctgagccaat tctttaatcg aaaagatacc
    23281 taaattatgt aatcttttct ccgtgcgatt tccaattccc cagaaatctg tcattttagg
    23341 aatagtccat actttctttt cgacatcctc ataggaccaa ttggctctca ttgtcggagt
    23401 ctttttagct tcattatcaa gtgccaactt agctaataag ggattggcat tagacatacc
    23461 taccgttgaa tagattcctg tttttctcca aatctttttt tgaatggccg ccgaaataat
    23521 atctaactta tcttttcgac taatcctttt atcaggcaca aaataattta atgaactggt
    23581 taaatcaata aatccttcat caattgaata gggataaata tcgtctggag ccgcaaattc
    23641 ttgaaaaatt ttttgaatct ccatattgac tgcaatataa gtatccattc tcggaggaac
    23701 aatcacagtt gattttgccc attcctctat ataacgaaca taatctatcg ttgtcggtaa
    23761 accttgcttt ctagcattat aataagagaa tttgcgagtc tttacatcaa aaggtaaatc
    23821 ataggaacgt ccaacgttcg actttccaaa gaccttttta aacataggag aggaagcaag
    23881 aattaaacca gcagaattat ctgcacgact cataacacaa agcgaagtct taagtgggtg
    23941 taatcctcta tctacacatt ctacacttgc gtaaaaagat ttcatatcaa taaaggcaat
    24001 gtcactttga ggttcgagac tataatcaaa ccaactcata cttagtcctc taaaggcata
    24061 aagttcccaa ctattttccc tataatgcga ggattctcat cataaggcgc aaacttatct
    24121 ggatagttcc gattgagtga aactaatcta agcccatttt cttcacgata aactttcttg
    24181 ataaaggttt gactgtccca atctatcgca tagatagccc cgtcatagtc aaatcctgtt
    24241 tgcttaataa gggctacaga accattttta taagttggtt ccatagaaac accagatacc
    24301 cacgatgcaa agtcataatc aaattgacga ttaaaataaa ctgtatcgta attaccatca
    24361 tcaaagtaag ctgttcccgt accagctgat aatttttcat aaaccttata agcaaaacgc
    24421 tcaggaattt ctacaacctt cgcattctgt ttgttcaaca attctgtagc ataatgaagt
    24481 gttgcttttt gattcttttt agttagcttg agataggttt ctactatttc aaactctgat
    24541 tcaaaatatc gagggtctac attaaaaatc tcactcaatt tgcttagatt attttgattc
    24601 ggttttgttt tacctgattc ccaattaaag tatgaagctc tactaattcc taaactagaa
    24661 gcaagttgag attgagataa gccttgactc tctctttttt cttttaattt agtaggtgaa
    24721 aacatctctt ctcctttgta agtttattaa ctaacaaaag agtaccatag cttcttgaaa
    24781 aaatcaagag tttaataaca ccctggattt aaaataatca taaactacaa gaaatcatca
    24841 ctgaagaatg ctaaaacttt tgaaaaaatt tgaagaagaa aatagagaat ataaaaaagg
    24901 atcgttattt tttaattgac gatccaatag actttatttt aaaaatctaa ctctacaaac
    24961 catttcgatt agttaaatct ttcaatcttt cttctccaga tttaagcatc tctttctcca
    25021 cttgattcca ttctccaaat agtaaatcat gaagaacggt tgctgctgaa gttgtatttt
    25081 cttttgaatc atatacacaa cttctatctc gttgataaat ttgaattctt tcaaaaatag
    25141 ctagttcttc caattgccgt gtattatcaa ctagatgatt tacaatgaaa tcatgatgtt
    25201 cttttgaagt tgcgcgtgct tgatttggat tgatagagta cagttcttcg tatcggataa
    25261 gagtactcag ataggacaat tcgggcttgg ttgcgattaa agctaattgt acttcatatc
    25321 ccttactttt caagagttgt gctgttttct ttggaacatc aatcgttcgt aaagttccct
    25381 ctatcaaaag attgtatccc aaatgactca attctgttac taaagactct accattttac
    25441 ctgcaaaatc tttggtgtat tctacactat ctttgccata ttcttgctgc agttctaaat
    25501 agcgtggatg ctgagaacga aaactatcac catctatgat aacaatattt ccttgaaatt
    25561 ctttctgttt aatccgatga attgtagttt taccggcacc actttgccct ccaagcaaaa
    25621 tcgctatagg ttgcttactg gacttttttc ctcttgtcag tgaacgaaga ttccgtgtta
    25681 gagcatgttt gaattcacta tcagtataat cttggatttc cattaggcta ccatccgttt
    25741 ttcagatatc tctaacatac gttcaattcc atccaaatag ccgctatacc tctctatttc
    25801 atcaaaattt tctactaaat agatattcgt atgaatcaag tcagatagat catcactcat
    25861 taaaatccaa ggattagatt catcatcaat gctaattccc tgactatctt gataacgata
    25921 gagtcgagat aatagattag cacctctttc tttcacaatt tcaattttta aagtcaattc
    25981 ataatcttca acaggattga gcattttatc ttctcctaca atatcgacat aagatacatt
    26041 aaacttctga caaatgatgt ctattaattc ggtagagact gaactcgttc cattttcata
    26101 acgactcaga ctatttcgtg aaatacctac aatccgtgca aagtcgtgtt gtgttaagtc
    26161 atgtgtttta cgtaaggatt ttatgttctt tccaatcatg gcaaactcct tttatttgat
    26221 accaccatta taacatttag aaaaagcaaa tgcaccattt ttggtgcgtt attgactatt
    26281 tttcctaaat ctctctaaat tcttctccaa ttgttcctta tgaagttgat ttttagcttt
    26341 ttttaatgtg tcgtccaaag tttcttccct ataagttgtt tctgttttta gttgttctga
    26401 ttcttgttct ggagtgaaaa tgatatctaa caatctgtca attttttcaa gatcttggac
    26461 agacatatca gatagtctat gaatcaactt cttaaatata tcactattgt cttgattttt
    26521 cttaaaaatt tttgtaaaca tctataacct ctcaaaaaaa gcagcctctt tagactgctt
    26581 agtgtaattc cgaaatcgca tcataaatgg actgcaattt cttattgtct ttattctttg
    26641 tgtcaatcaa cgtatgtagc tcttcaattt tcttttgact actttcaata tcgctattgt
    26701 tatccgcaat cagtctttta agatgttgct gataacttgt agtgatatct gtctcttttc
    26761 ctgttctaac ctctgtaact ttgggtttag aactagaatt tgattccgtc acaggtgctt
    26821 gtttacgctt ttgaaaagct gcttcataat ttacatcatt acctccttga tgatttctaa
    26881 ataaagccgc aattttatct ggatcttctt gattttctga tttactttct aatggttgat
    26941 taaaattcca atcttttgtc attcactcat ttcatccttt ctaaattcag aatcatcgaa
    27001 ttgtctttct ttaccaaagg catggtcaag agcttcttca aaactcatgt gactaatgct
    27061 ttgacgcctt ttgaacgtcg caaacatcgc tgtctccagt tgctctttgt aagcagctag
    27121 tttttctgtc tctcttgcta ccttactttc ttgcctagtg accttttctt ctaagcgttc
    27181 aataatggtc atatactatc ctccttcatt ctaatattag ctaaaacatc ttgattttgt
    27241 tatcacaatt ctaaacattg agaggtttgt cttactggtt gattcctcaa tgtctctttt
    27301 gcagactcaa gtatcaattg taaatctgat ttcttttctc taaggatatc attccaatct
    27361 attttttctt tcccagattc gttatcaggt aaatccagta aaacaggcaa tccagcttga
    27421 aataacttat cggaaaaatc ttttcctgca tcatcacaat ctaccgcaag tgttaataaa
    27481 tcgggatgat tatcaaaata agtagttgta tctcgaattg tattcatcaa aggcaataac
    27541 tttgaaggta ttactgtatc taaaaattcc aacttctgat tttcttcagc tatcagtcgt
    27601 aaagtttgat aagcgacaac agaccttttt aatccctcca tagataccaa acgaacatca
    27661 gttagacttt gttgatgaag ttcgtaatag ctcatcaagt cgacgaacga ttcacaaaag
    27721 accagtctat ttggtttacc aatgtcaaag gatattccaa tatgtccatg gcttcctttt
    27781 agaatcgttt ttaacctctc tctagaaaga gcgggattct tataaatccc ttgtaagctt
    27841 gctgcctgca gcttgtgacg atgatcaaag cttttaaaaa caataacaag ttcaacagtt
    27901 tcatttgttt tccaactggc ttgtgccatc aaaccttgtt gaatcatctt ttgtacgatt
    27961 tcttctgaga ttcctctaca ttttgttaag taatatcttg ccagactaca gttagaatct
    28021 tctactctct ttaaaggata ataaaatggt ctctctcttt tttcttgaac agcttctttt
    28081 tgaaaaggtt cttcagaaag aaaagctaga gcatctttaa aagagattcc cttaacaagt
    28141 cgaacaaaat caataacatc accttgaata tctcttgaaa accatttaaa agtattggta
    28201 gttgaaaaaa tccgaaatga atcgtgttca ggatgttcat agacacggct agaaacttgt
    28261 ttaaaggaga tacctaaacg attggctaca tcaagaattg aaatttgctt acattcttct
    28321 atttccatgc aatatcatca ttttgtcgta gtatttggca gtgatggtat tgatgatgat
    28381 tcttctaaag ttttaggagt taccttatct aaatcatcta acccagattt ccaaacctgc
    28441 acttgattga ccaataactt acctggtagt ttagaatagg ataacttaac tgttcttgtt
    28501 tctgtctgat tagtctttga ttggttggca ttctttaaat cagatacata ggttacatta
    28561 taagagacca tggcaatagc ttgattcgta gtctgattaa caaagatatc agctttttca
    28621 aaatgataat ccaaaatata gtccttatac acttggttca tggcatcgtt ttgactggtc
    28681 aattcttgag aatatgccga ttcagtcata taaggttgaa tacgtgtatt attttctccg
    28741 agcttttctt tcgtatagta ctgagtcaaa aattctttta cagtatccga tgacaaaatg
    28801 ctggctttat cttctgcttg tttatcctct acaagtttag ctgcagccaa ttcgatttct
    28861 ttgcgacttt gtttagcagt tgagtgttga ccagcagtat atcccatcat gagaataaag
    28921 ctagttgcag ccactgctcc aacactaatt aaggctttag ttttgacttt atttaacatc
    28981 ttagaccttc tttctataaa aactaggtca agaataacaa aaagaacttg taagttttat
    29041 cacatcacaa cgaaaggtaa ttcctacatt tctggcgcaa aatcgtacag ttcagagaaa
    29101 aatgtcaaaa ccagctgtct tcagtttata atataaatat gaacaaatta aaagaagaaa
    29161 atttgagaag agctctttct catattgaac gacataaaca agccataaat acaactaata
    29221 atagtgagga taatgatttt cataaattat tactccaatt tagctatgaa gtatatgaaa
    29281 gaatcaaggc aaataaaaaa ccttatccga atttagattc agataaagtc ttttaactat
    29341 ctaaaaagtt cacatttttt ccttattcat ggagttaatg aagcgccaac tgaatcctag
    29401 aaccaacatc agattgatga aaaggtacac agccgtaaaa ctagttaaac catgttgtct
    29461 gatatcatca aaatataaag taggttcagt aaagaacaga taaattccat agacttctac
    29521 gaaaataaga aaactgacaa aaccaatcag gaaaagtcta ctggcaataa gaaagagtct
    29581 ccataaaaga atgagaatcc ctcctactgc taaaaaaatt actgggataa ggagtaaatc
    29641 attcatgact ttctcctttc tagtcaatca attgacgata atgggtggca agagaggaat
    29701 caaactcttc taatttttga actaagtcca aatactcctc tttttcatgt tcttcaaagt
    29761 ccacacctcg atgattctga agagagattt ccaattgact agtgagttct cgtttagaaa
    29821 aactgtaatc gcctgtcact tcctcataat gttcctttag ctccttgtag gcttggtatt
    29881 cttcaggcgt ttgaaatccc tgtaccaagg cctcttctaa ttgataatag gtatcttcca
    29941 tcataatcgt tacctcgttt ctttctatct ttattctacc gcgcttttct tttcttgtcc
    30001 gctatttata tatatttttt aatctaattc aaaagaaagt tgttcttgct tttcttttcc
    30061 tttttcgtgg aattgtctta aggcctgatc tataatatct aaatccgttt ctgtttcaat
    30121 caatggcgcg agtacatcgt attcggcctt tttagtttga taatcctctt cctttggaaa
    30181 atttttctca atttcaactt tagcagtagt ccatttatcc tttaattcat ccaataagtt
    30241 ctgagttttc acttggtcct ctttaatgtg atcaattgta tgctgaagcc tttgaattgt
    30301 ccccaaagga gaatacaaat ctaaactgac agaatactga ttttctccta caatcttaac
    30361 agagaaggtt tcaggaagag gttgatttat tggaagacta agcattttaa tgtcaaatcc
    30421 tcgatagctt gctagggtac gaaattcttt gctgtcagct tgattatgac ggataagacg
    30481 gtgtagagat tcacctgctt cagctcgttg atcaaaagct tgcttaccta ccgtcataga
    30541 aaatgcctgg tctttcgata tttcagactg ttgaatatcg ccttcatact tgcttaatcg
    30601 tttctcaaga atgggcatat tttcttcaca gtaagagatt gtatgacgat agtgatcctt
    30661 gctgcgttga aaggcgcgtc tttgattttc taatagagtt agatcattct ctagttccat
    30721 cttatatttg agataaggat tacctgttgc tagtgcctta aaatcagaag ctgtcatggt
    30781 ctgctcatca atgtcttctg cagcacgaat cggctcctta gaagtcataa tctgcttaat
    30841 ataacggagt ttgttctcct gagttgccca tagataatta tcaaacgaac ctttggtaat
    30901 atagtggtaa atatccactt ccttgttttc atttccctgt cggataatcc gtccattgcg
    30961 ttgctgaatg tcacttggtc tccacggaac atccaggtga tgaactgctt tcatcttgct
    31021 ctgaacattt aaacctgttc ctcctttttc agttgatgca agaagaatcc gcacttctcc
    31081 tgcattgacc tttcgagaca aactattctt cttttcatca ctattggcat catgtacaaa
    31141 ggcaatttcc ttactaggga ttcctctatc aaccaataaa gcctttattt cagaataaac
    31201 atcaaagcca ttatcttttt tcttaggtgt tccaatatct gaaaaaatca tctgagtagc
    31261 cttatttccc attccctcac gataaattct ttcaacatta tcaactacct gaagcagttt
    31321 atgattgtct gctagactat agctagagtc caataaacgc atatcaatag ctagtttccg
    31381 tgcctcaccc gtaatcttta acatgttatc ctggctcgga tcaactgttc cacatttgac
    31441 cgcatctgac ctcataacca attcttctaa atagagtttc tggttttcag ttaactcact
    31501 ctcaataggg ataatatggg cttctggtac aggtaaatcc aacatatctt gtgtttgaat
    31561 gtcggctgtt tctttataga ttttcatcaa ctcaggtaga ttgacaaact ttttaaatcg
    31621 tttcttaggc tgatacttat cccctgtagg agctaattcc atagagtttt gaatttctcc
    31681 aaaagcacct acccaagagt caaaataatc aacttgatag cgttttaaga tatctggttg
    31741 aatatagttc atcatagtat ataactcact aatagaattg gaaacaggtg ttcctgtcgc
    31801 aaagacaatg tttttaaaat catgctcttc ctgaatctgt cgaaccttca tttccatatc
    31861 cacgttcttc ttagaggttg tattggtaat ccctgctaca ttcccaagtc ccgtaattgg
    31921 acgaatattt ttaaagtgat gtgcttcatc cacaaagaga aaatcaattc ctaagttctc
    31981 aaaatcaata aaactatcac gattaaagcg ttggagttct tccaattgtt tctctagacc
    32041 acttattgat tgctctgctt ctttaacagt atacttattt tcagaatgtg ttttaatctc
    32101 tcgtaattca ttgagtttat cctcgatata attcatctgt ctttccttac tgacagggat
    32161 tttttcaaat tgagaatccc caatgacaat ggcatcgtaa tctcctgtaa taatacgtga
    32221 cacaaattgt tttcttcttg ccttaacgaa atctttctta gtagtcacaa agactttttt
    32281 agtagggaaa aatttcatga tttcttggcc aaattgagca gacaaactag aaggtactac
    32341 atacaagggc ttatgaacca tccccaactc ctttaattta aacccagcac caagcatggt
    32401 caaggtcttt cctgaaccta cctcatgagc taacaaggct cttttttctt ctacgattct
    32461 ttgaatggca ttctcttgat gaggacgaag actgatgttt tgtgccaatc catcaatgac
    32521 tagatggcta ccgtcatact ctcgacttac cgttcgatta taaagacgat tatagctttc
    32581 ctcaataact tgttggactt ctggataccg tgagacaaat tcttgaaaga gctcttgtaa
    32641 atgctgctct tttgctctta gaacagaggt tttttccaaa tctgtgatgg tctttttctt
    32701 ttctccttcc gtaacagtca tagtaatcgt cggttggttc gaattaagta aattctcaaa
    32761 aatctttctt cctgtatcat aacgtgaccc actaactcca agactactat ctttggcact
    32821 tggatagcga taagcaaatg atgtccttaa atgaacctgc ccatcgacag gattcacttc
    32881 aataacttgt tcaacatcag gtgaagacaa ttcaaattca cgattggtaa aacattcaaa
    32941 ggcaaattta ccgtaaacgg attgaggaat ccaacgtgac cctattttaa actcaatatc
    33001 tgccagatga atccttggag ggcgaacaga ttctaacaaa tctaaagcat ggttccaatc
    33061 atattcttgg ttgttttcct ctactaatag ttgaactact tctatcttgt tgagaatatc
    33121 tcctgataaa aactggttct tagaaagata ttttctttca cctcttaaat agctttctgg
    33181 atccattaaa atctggtcac ctaactcatc taaaatagca gcttgactat gttcagggta
    33241 aattgatacc atatagtcta aatcaacccc tctaccatcc gataaactag agtttaaggc
    33301 atctaaagcc gttgatactc ttgtaatcac tctctccggc ctaaccaatg ctttctcaaa
    33361 ggctaaagat tttttatatt ttactttctg atctttagaa tcaatgtatt catcttctaa
    33421 acttgctagt aaagaatact tatcgtcact atcaaataag ttccgattaa ctgaggcatt
    33481 caagtatcca aattgactta caaaacggtc ataatcacga ttgagtttac taagtaatat
    33541 ctgaaaatca gaccgactat aatctggatg acgttgaatt tcaattaagg cttgataggt
    33601 ctctctcaaa tcaaccatac ccttaatgcg actaatatcc ttatccgata agggactttc
    33661 ataaaagaca gtttttttga acagtccctt atatttccct cttttactcg cttcttctga
    33721 cttgtataca tctagtgctt cctcatctgt caaatgaagt tgcacgaatc gatctatttt
    33781 atgttcagac aaagaactgt cccaggcttt aaattctccc ttctcgtcta cataataact
    33841 aatttcgtct acttttgaac ttttccgaat gccatgcgta tctcggtaat aaatttgatt
    33901 tccctcatat ccaaaagaat agagcgctaa gtcctcacat atacgacttg ggatagaatt
    33961 atctacttct tcttggataa aaacaggtgc tttcaaagaa ttgtcaattt gtttaggtgc
    34021 ttccacattc tcgaatgctt tcattatttc agtaactaat gtttctgata cccccttaac
    34081 attgagagtt cctccattaa aattacgcac ctcatattga cccaaaactt gtgtattgta
    34141 tttcccatca aaataaggat tgatccagac acgcttatcc tcttcaaagg gaatagagcc
    34201 actaaagaca agttcctcct cattaagatt ctttgcttga tccttttgaa agaagagaag
    34261 atctgtggtc actcgagtac ctgcaatctt tttaaaagcc gtatccggca aacgaactcc
    34321 ccctaaaaaa tgagtgttag atttaatctc ttgtaagaca ttatctgtcc gcttatccat
    34381 tgtccctata gatgagataa tcgacacttg tcctccgtct cttactaaat caagtgagtg
    34441 tttgacaaag taatcatgaa tcatgtaagg tttatcatag tttttatcgg caatgcgaaa
    34501 atttccaaaa ggaacattcg ttaagactaa atcaaaacta ttattttgat agggaacttc
    34561 ttcaaatcct cgcacttcaa tatgggtatt ggggtggagt tgttttgcga ttgcgcctgt
    34621 cacactgtct aattcaactc catagagttc tgatttatct cgtatacttc taggcatcgc
    34681 cgcaaagaag ttcccagtcc ccatagaagg atctaatatc cttcctccct caaaaccatc
    34741 atccagtaat ttttgccaaa tctggcgaat aatcattggg tctgtataat aggctgtgag
    34801 agaactttgt ttcatagtgg agtactctga tttacttact aaactcttaa gagttaaacg
    34861 ttctgtttca tactttggat tgagttcatc gaaaaattca ttggcaagac caccccagcc
    34921 gacatacttg gctagtagct cttgttcttc tggattcgct tgtcgtccct ctttttctaa
    34981 tcttttaaca agttcaattg cggcgatatt cgtttcaatt ttttctcgat ttgtcttagg
    35041 ataaaagtcc tctaaatcat ctggaaaaac aaaatcttga acagggacat ccgtctcttc
    35101 tatgcctaca ataagcgttt ctgtttcttt atccttttcc ttttcctttt cattttcatt
    35161 ttcttcttcc aggtaggaaa acaaatctat ttcctgactt tcacttgatg aatcaatctc
    35221 aatctctgaa tcttcttttt caagttctac atgagacaat acttgttcaa tctcttccaa
    35281 actgttcaag tataagatag gattctcttc aaataactgg ttggaatctt tgaatagctc
    35341 taggcgaact aagtcattta actgtgcatt ttcaatcgaa accaactgaa atacttgtcc
    35401 tttataactt acttgtgaac cgattggata ttccctcaaa gcttcttcta caattttatc
    35461 gatattagaa aaggagttcg tttcttccgt ttcctgttca atatcacttg aaggagataa
    35521 ggattccgct acttgcttag acttttctct tatagccttt acttcatcaa aatgagtaat
    35581 aatcttcagc ttttgtgtca gtggaagttg ttggtagttt tcttcatgat ggacaagatc
    35641 cgtaacagta tctaaagtag ccatcaattc tgaacccaaa taagctagaa catctccctc
    35701 tttttcttca aaatgaatct caagaacttc ttttttaagc tcttttgagt caaccattag
    35761 aagaaactcc tctatatctc tactaatgcg gtcagataga ttattcgcaa cccgatagac
    35821 attgactaaa ttgacatcct gtttctgatg acatacaagc tcacttaatg gtgttagttt
    35881 ctctttttca gattggatat aaaatcgagt ggaaaggtta taggttgcga cttctagcac
    35941 caagtttttc tcaaaattac ttaattgaga taatttactt agacctgctt gtccaaaatt
    36001 tcttgtgtaa ctttctaaat cttggtcatt attttcagaa ctagcctcta ggaaagaaat
    36061 aatatcttga tgaaacgaat acacatgagg tatctcttct atcttgccct cttcaaccaa
    36121 aaaactctct accaagtcct gccatttctc atcaaaatgt tgcgcctgat agcgaagaaa
    36181 taggtccatt ttctccctat cttttggaat tgttccacga aacatagcca ataatttcat
    36241 tacttccata ctcgctcctt tcatctatac gaaaatagga gaatcacatg attcccctac
    36301 aactctatct ccatttcaac cttttgagga ctggtttcta aatcactaga caaaagagaa
    36361 atagaatctg ttctcatgta gtaagtatat aagtcttcta ggtcttgttc gttttcaatc
    36421 cctgtttcaa tactaataag agcctgtata aattccttgt agtgactctc catcatatct
    36481 gaaatctttt gtttcatttc cataaatact gaagacggtt cagttatact tgtttggtct
    36541 atgtcttgta aatccttttc taagggattg gttccttctt ctacttccac taaatctgaa
    36601 cgtccatcac catcagaatc tgcgctaaga ggattggttc ctagcgccaa ttcttgagca
    36661 tcagttaatc catcttgatc cgaatcacgt tgataaatgc cttccatata cttccttctt
    36721 tcctagttaa tcttttttca ctccaatcct accaaatatt ccttgaaaga agtatcacaa
    36781 caaaaaaaga gaacgagcca aaactgcgtt ctcctgaaaa tgataaaaat atattttatg
    36841 ccacaaaaga tatgtaaact aatcttttaa ataataaaaa agttccgacg tttgtaaatg
    36901 ttttgagtaa attgaaatta ctttttgacc ttttggaaat actgtctttc tcttcaaatc
    36961 taataaagat tgaggaacaa ttttccttga tgtctctttc aatgttaatg ctagtatctg
    37021 ttttcttgta cgtagagcat aatcaaactc caaatacaaa taacgtcctg aaccagttag
    37081 atgaacatgc tttcccaata actcctcaat ggatcctaaa acttgtaact tttgcatcgt
    37141 ggttccatct ttttttattt tcaactcatc aattatgaca tgtctattta aacaatcgtc
    37201 aaagaaacta cctgcacctt tttggtaatc aacaccacat aggtgcatga aattagtagg
    37261 tgaaaaatga agttcaacac tttctatttc tgtttcataa tacatgattt tgccaacgaa
    37321 gtgttcttta aaaaaagaag ccgcaatttg taactgagta aaaaaacgct gaagttttat
    37381 tttttcggtg taatttggat tacgataatc tctagaattt gccatatttt cctcacaaaa
    37441 aaggtggttt acagagtctg taagccacct agtcagtcgg tttattctgg tgtctgccac
    37501 cgcttggccc ttacgtccaa gattgctatc ggatttcgtt ctggtgtccg ccaccgcttg
    37561 gcccttatgt ccaagattac tatcagattg accatgagcc gactactcat ctacactatt
    37621 tattctacct gaaaatggtt aaaatttcaa gtgtaaactc ttctatttcg tagtataggc
    37681 aaaacttatt gcactatctg cttgagagat ttttctaaag gtatagttag ggttgccacc
    37741 atagttggtt tcagacacaa ggaaagaacc gtcatcatat actttctcga caaaagccac
    37801 atgaccgtag atggctggtg taccatgtgt acctcccaca aaagaaacaa tggcacctgc
    37861 tcttggtgta gagccagttt ccccaccaag acttgaagct gtcgcaaccc agtcctgacc
    37921 atttcccatg gtattaataa ttgaaatctt ctctccatta cttcctttta attttaagcc
    37981 taattggttc atacgagccg caacgcccca tgtacattgt ccataggcat aggccatacc
    38041 atctccacca ccaggaacag aatgatcata caagtcccca cgaacccctt caagggattg
    38101 tgggtcactt tttgcctgtc ctccatttgt ttggctgaag cctttttcaa tttggtaata
    38161 ccattccgtt gctctggttt gtctttccag tagtttgtca ccagaatttc cctcccaata
    38221 ggtgaggaag agttgggcga gattggctgc actgcccgta tttttaaaga aatcttttaa
    38281 ccaactttga tagtaaggac tatccccatg aagcataaaa tcaagttgga ggtctaaatc
    38341 ataccacttc ttatttttgc tatgtgcata attcaataaa gctgtatgac gtgttgaacc
    38401 atctgcagta tccgtccatt gacctaaccc caaacctcta tgaaggatat taggataagc
    38461 accactataa atggctggac ctccaatcgc taaccaggtt tcatcatccc atgaggaagc
    38521 ggtagcgcca actggaggag ataaataatc tccctcagct cgtttaggat tgatagaaga
    38581 ctctaccgac caatttccta aaatagctgc aatggcttgg ggacttgccc cttgagattt
    38641 caaaaactca taaatatgtt tcgctcgttc aaactcatcc ccaccaaact gaccaatggc
    38701 aggtaagata gttgtctgaa gttgaatgac ttttggaaaa taaaattgcg gattaacata
    38761 caccaatttt tctttcttgt tcttatactt ttgataggaa actttcaaac ctgtatcatc
    38821 tggtgtctca ccaataacat cacccgttag gactcttgtc ccctcaatcg cacggccatt
    38881 atgaatggaa tataaggtta agcgactctc gttttctcct tttccgttag tgagaataac
    38941 attgtcgcca tctagagata caactccatc cattggtgcg acaattgctt ggtgagcttt
    39001 agcttctagt agaatgtact cctgaagagt aggttttccg tctaaatcat agtatccata
    39061 acgataagtc atggttaaac tatcttcgtt acttttccct tcaaatggat tgtccaattc
    39121 ctgcatggaa gcatacacac cttcttcttt tagttccttc atttcctctt gatcgtcttt
    39181 cgatagttta tacttaggag tttcataaag gtcttgcatg gatttcaaat cttccccatc
    39241 gtttaaatca tgccacaaag tagatagata atccttgtaa gtttctgaac taaataagtg
    39301 aactggtttg tgtaactcat agtcatggaa tttaaagttc atatacccca tcacatcatc
    39361 aacttttgtg taataggtaa ttcctttgtc attggttcgg gtatgttctg cgtcttccca
    39421 agttaggtgg gtataagctt ttgttaattc aaattcatct tgttgaatta aactagcaga
    39481 tgaaaatcct aaaaagaagc tcatcataag taaaagaaga aagactattc ctccaactat
    39541 ccaggttgca ggattcccag ccgcaaatgt aaagaaggaa aaggctgctt ttagtttttg
    39601 atagatattt cgtacacttg taaggccttg tttctttaat tttcgatacc gatttttaaa
    39661 ggaacttgga ttatctttcg ctagtttcca tccttttcca tccttaaaat gatggtatcg
    39721 ctcttttgtg ttggtcagtc ttttcttggt aaaacgacct gttgcttgtc ctgttttgac
    39781 actagctttt ccaagattat aagaaagccg actgtagcgt ttcccttttc taatggtctc
    39841 ttgaagtgtg cgatagcctt ctaaatcttc attttctgaa gctaactctc caccttcacg
    39901 tccaaggaca taaaggaaag ttttggcttt cctactaacc tttttggatt tataggcttg
    39961 tttagtagat tttaaatttt ctttggcgtc cttgacttct ttcttagctt ttaattcttc
    40021 taaactcttc ccttgaaaga aaaaatttga ttttgctttc gattcctgac cgtagagaaa
    40081 tttttgattg gtttttcttt ctttacgacc ctcttttctt tcttcttttg cttctacctt
    40141 ggcttctcta aattgcttct tggctatttt caatcgtttc ctagcatgag gcaaccgtct
    40201 gtctcttaat tctttgcgat tcaaaagaga tggaggacta ttttgaagaa tatgattgta
    40261 gtcttcattt gcttgtttta ctctctcctt tgaagcctct ctcatctcct ctagcttttc
    40321 ttttatctct tttttccatg ctttttcatc cagtacagcg gaatcttttt tctgtttcct
    40381 tacctccttc tttccttttt tcaagaattt tttctcatct tttaggcttc ttctaaatgc
    40441 ctttcgggca cgtatgattt ttcttttatc cttcattcta cttcccctta attagaagcc
    40501 attttatcag gatccgtact catgatatca aacaattgag taccttgagg aatcttattt
    40561 ttaaagggta cgacaactga accagctttt atcagtcctg cccctttttc tggattgaca
    40621 aggtattttt cgagttcttt tgacaagcct aagagttgaa ccagttcttc tcggtcattt
    40681 tttgcttgct tgaggagaat cataaattca ctatttgcaa taatccgtct accatttgga
    40741 tctaacaata aggtttcgac gttttgagtt atcccagtcg gactagctcc atattttctg
    40801 acacgactcc acaatttaaa gaagaaatca ctggcatatt tatctaataa gagaagctgt
    40861 atttcatcaa aataaatcca ggtcttcttc cctaattttt ggttccgaac aacacgattc
    40921 catatctgat caaacactac cataagagcg atttgtttca gctcatctcc taacttttta
    40981 acgttataga ttaagaagtt agatcctgtc tgaatattgg tcttatgaga aaaaatatca
    41041 agagaacctt cgacatacag ttccatatca agtgccaaat tctgcgcttc ttcttctggt
    41101 tgttgactca agacaaagac ccattcttcc aaagaaggct ctttaaatga ctgataggtg
    41161 agtctggtga ctcggtcgat aatcgatttt tctcttccat ccattttcct atccaataac
    41221 ttgccgataa aggataaaag aaattctgat tttaccttaa caggatcctc atccatattt
    41281 tcatcagaca agtcaagtac attgagatag gtttgggaat ctggcgcaat atcaatcatt
    41341 tctcccccaa aagctcgtcc aatgacactg tattctgctt ctggatccac gatgataatt
    41401 tcagtatttt caccagattc cttgattttg gtcgtgataa tctcatgctt agttgccatc
    41461 cctttcccag ctccagatgt ccctaaaatc agaccagacg gtgtatttaa taagcttcga
    41521 tcaatagtaa taatattgct tgagatttga ttgataccgt aatatttccc actgcggtct
    41581 tgtaagtcta ctgaagtcca aggtgagttc actgctacat tagatgttaa taaactccgt
    41641 gatactccct ctaaaaaatc acaaccaaat ggcagcaaac tattaaaggc tgcttcttgc
    41701 atatatggaa gtttatcaat cattaggtca tttgagccgg ccacttgttg aatcgtatct
    41761 agagcttgtt tgagttcttc ttcatcctga ccaaagatcc caatcaagaa gaccgtttga
    41821 aacagtttat cacctgtctc ggtcatggtt tttaaaagtt cttcagcttc atcgatatta
    41881 ctttctaata catgacctac tttttccaaa tagatacctg tacgagctag tttttgttgt
    41941 tccccaatct tttgggattc catcaaggtc ttctttgttc gtagtttctt catggcatct
    42001 gccttggtcg aactttgagc atgaaggctt acaatcaatt ccaaatctcc ttgcataagg
    42061 tctcgaataa actgatcccc taattccatg ccgtagtctc tgacatagac aatctgtaat
    42121 aagcggtcat tgatttgtag gtaattcttg tttttaaaat ccaagagatt aggggctatg
    42181 aagtgacgag ttgtctgacc agatctcgtt aaatcacggt aagaaaaagg aagatggtgt
    42241 tctcctctaa gcatgtcggc caacaagttc acacgatctt ctccagccaa ggattcaaat
    42301 cgagcatcaa tttctgagaa accactcttg aaatattctc ctatttgaga caaggaacga
    42361 taggcttgtt tgggattaga atcctttctt ccaaagctaa tcagttttac agccgaaaag
    42421 ttattttcac cactatctaa attctgattc atcatccgat tcaattcttt acgataggta
    42481 tcatatccat cttctttttc ctcatacaaa acactttgtc taaacttttc taaattcaat
    42541 cttttattaa agatagtcaa ttggaagttg gtttggtcat ctagtgagtt aatcaaatca
    42601 gaatacttct caatgattgc gcccttatct tctaaaccaa cggtctggta attgacatca
    42661 ccaagtaaat agctttgtga gaaataatct tcttttacct gcatcagacc attttgatac
    42721 agggcttgat aggaaagagt attagccgtt gagggtaaca cttcctcttt tttcccttta
    42781 acttcttcct ttttattagt cattgaagtt ttttgtttct ttaatgtatt tgattttctt
    42841 ttcatgttca ggtcctttct ttcctgtaat tgtgcgtagg ggaaccgtta attcaaaatg
    42901 aagacggtat ttcaaataat gttcaaaata taaatcattg ggtttataga ctccaaaaag
    42961 cattaggggg atggtaaaag caaacacaaa accgtaaaca aaccaatctc caaattgcca
    43021 gaaaaagaga ttcaagccca aaacaataat tgtgacaata aaggctggta aaacaaagat
    43081 gatttgtctt gtggtgaaac ctaaccaagc cctgtgttgg tattttgaga tgtctttaaa
    43141 gacacgtgta ttcatgactt tcctttctaa aaaggctaag aagcaatcac ttcctagcct
    43201 ttatctaatt acatacctaa gattgagcga gccgtacgtt gagaaccaac gagggcaata
    43261 atcagtaaga tagcttgtac taaactacca aacataatcg caagtgattg caagactcct
    43321 gcaccatttg aaacagctat tttcccagca gattcaaaca aaggaacaag agaaacaatc
    43381 agaaaaatga gaaccccttg taccgcatag accataatat tttttaaata gccaatacca
    43441 atagacttcc attcatcact taaaaatgtt ggaatcgtaa gaggggcaaa tgggatcata
    43501 aggtagagtt gaataaatcg aatagatacc aaaagattaa ccatggctgc acttactatc
    43561 cgaacaagcc agataaggag agcgaaaaag cccacaatca tgcggccaat aaatcctgaa
    43621 ccttttaatc cagagagtgt atcatacttc gccccaccgt gagccacaat cgaggccact
    43681 tgttcgatgg cgtgactcgc aatcccgatg atagcttcta ctataacggt agtattggta
    43741 atgaccactg cgaccataat ataactaatc aacatcggcg ctaatgcttc aaaggtcatc
    43801 gctccaccag agttagcaat cttctttgcc atcttcgaaa attctaagat gagaacaact
    43861 gataaaatcg caactccaag aggctgcatg acacttttag taatactaga catataagtc
    43921 caaactgttg gattgtagct agatagggat ttaatcagat ctaccgtaga ttgtaaatcc
    43981 acattaaatc cttcaaataa attttcagct gatatttttt cagatgcaag gtaaacaaag
    44041 ggtgagacta aactaagatt catgtcattg tttatcctcc taaattgaaa tctgggttac
    44101 aaaggctcca gcagccccta ccataacacc accgacaatt tcaagaatgg cattccgaac
    44161 acctggtcca ccatctttaa tgttggttgc aaggttgaca atccccacaa caacgagaaa
    44221 ggcaccaact gcaatcaatc ccttctgtaa caaagacata gcttgtgcaa acatagcact
    44281 tgcgtctact ccataaacaa aacctttaaa atgcgtaatc atctatttcc tcttttctat
    44341 ttttatttta aactagattc aaaagttaaa tcacgaattc taaggtcgtc aagataattt
    44401 tcttgtcttt gattcaaagg attgatttga tagttccacc accgttcatc gctttcttga
    44461 ttagctaggt acttccagtt tggatgctta gtggaattgt attttttgct tttaaagaca
    44521 ggcatattgg caattcgaac caagcattca tgccgtttca tatttccgac ctcatcgggt
    44581 gtcattaagt cacgagcaat cttttgatga gaaagggatc ctgaacctgt ttggccaaag
    44641 gaacgactag tatttcgaac atcaatggtt tgtttaccga gtaagccact cataaattta
    44701 aaggtatctt catcattacc acctaagtag actaagctat cacagttccc caaaatggtt
    44761 ttccaagctt ctttttcttt atagagccct tgaagttggg caatattttg aagaatagga
    44821 acgagactca tatttcgaga acggactgtt gaggtttgtt cagcaaaatc tggaatttct
    44881 ccgatatttg cgaactcatc taagtaaact ctcacatgaa gaggcaattg acccttaaaa
    44941 tcaatatctg cttgtcttgt tagggtttga aatacggttg aaaaaaagag ggctgaaaga
    45001 aagcgaaagg tactatcgtt atctgggata actaagtaaa ccattgattt ttccttgccc
    45061 catgtcttca tatcaagggt atctcttttg gtcaagtcca tgacactttg aatattgaag
    45121 agggcaaatt tagcagtggt tacagctata acagaatcca gagtcttatc cttataattt
    45181 tgaaaatctg cccaatttcg catggtaaaa ttttcagtcc catacttttt agcataattt
    45241 tcaaatagaa tttctaagac acttttttcc tggttttcac ccttagataa gtgtttaatg
    45301 agttttgaga tttcagcaaa acttggataa cgacctcgtt tttttcgctc ttccacttct
    45361 tttttttgac gtttcaacaa gttttgatat tccttttgac ttaaacgact ttcttctatg
    45421 agctgttctc ttgttttagg tggattatag aaatcgacta agtaagaggc taaagctcga
    45481 accaaagtca tagaagcttc atcccaaaat ggaccacttc gggagccaga gcctttggtg
    45541 ttattaaaat aaacagtcag catgcgattc aaatcgtttt ctgtttctat atagcgaaaa
    45601 ggattaaagc catctgagtt cttcatattg actaaatcta acacctttac ttggtagcca
    45661 tgttctaaaa agagtttgcc tgttttctcg gccaagtgat ctttaggatc cactacaata
    45721 ttagaactat tcatctgaat cagattgggt ttcacaaagc gaaatgtctt cccacttcct
    45781 gaacctccaa tcaccgcaat attcttattt ctatcatatt ggggtggttt tttatctaat
    45841 aatgtcaaac gaacatcttg tgctaagatc gtatcatgag aaaattcctt accgtaaaag
    45901 agcttctttt cttttagagt tccaaaacgg gcgctcccgt attctacccc ttctcggtat
    45961 tgttttttac cagtctctag atagagataa accagtaaca tcatcacaaa acctagtaga
    46021 aaaaaagcac ttgattttcc agtaaaagaa acattccatg gcgactgaag aacttcatct
    46081 tgaccttcca tcagaagatg agtccattta tctaaggtat ttccagtata ggaatcatac
    46141 aaaagcgtca aacgatgaaa aagatagcct agtaagatac ctaacagtga gaatagtagg
    46201 aatttttttc cactgtacat catctcacca tctctttctg tttgacggct ccttcttgtc
    46261 taaaggtaat ttgggattta gcttcatcaa tagcatcatc taatgactta tccatggtaa
    46321 aatcagctaa tttctccgga tcattaacca ttttttctaa aagatggtct aaatgattgt
    46381 ctaaaatcga acggtctttc gcgtagaaat gtagagaatc cccttgccaa gcgatggcta
    46441 aaggaatctc ttctttttct aaaaaagctt taaatttctc tatatcaatt ggtttgtcta
    46501 aaaaatcttt tttcagatta atcgtatcaa tcgcataggg agattgtagc aattcttcta
    46561 atttctgcac tcctatctta taggcggaat cctgtgctaa agcctgacgt ctagaccatt
    46621 ctagaatctt taaaagactt tttacagtaa ataaaagact acgctctgca tattgaactg
    46681 ccattcgttc ctgttgttca gaggacatct gatgcctcct tcttcacaaa tagcagcttt
    46741 ccttctttat aacgataagc tatcaatttc tgacgttgct taatcgactt gacaaccttc
    46801 agtagatctc tcgaataagg ttctcgaaga gtgacttcta ctgccttccc atcaacgata
    46861 ccaacacgtt taaattcaat gtagtctttt ttgagatgtc ct
//
LOCUS       DAVBOD010000011        43433 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 640-05
            SAMEA1012484-rid20186543.denovo.011, whole genome shotgun sequence.
ACCESSION   DAVBOD010000011 DAVBOD010000000
VERSION     DAVBOD010000011.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012484
            Sequence Read Archive: ERR059358
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 43433)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 43433)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979948.1
            Genome Coverage       :: 595x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:03:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,266
            CDSs (total)                      :: 2,219
            Genes (coding)                    :: 2,091
            CDSs (with protein)               :: 2,091
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 71 of 128
            Pseudo Genes (incomplete)         :: 50 of 128
            Pseudo Genes (internal stop)      :: 33 of 128
            Pseudo Genes (multiple problems)  :: 22 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..43433
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012484-rid20186543.denovo.011"
                     /strain="NIG 640-05"
                     /db_xref="taxon:1313"
     gene            1..73
                     /locus_tag="VQ862_000655"
     tRNA            1..73
                     /locus_tag="VQ862_000655"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:34..36,aa:Met,seq:cat)
     gene            87..160
                     /locus_tag="VQ862_000656"
     tRNA            87..160
                     /locus_tag="VQ862_000656"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:121..123,aa:Ile,seq:cat)
     gene            171..260
                     /locus_tag="VQ862_000657"
     tRNA            171..260
                     /locus_tag="VQ862_000657"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:207..209,aa:Ser,seq:tga)
     gene            271..344
                     /locus_tag="VQ862_000658"
     tRNA            271..344
                     /locus_tag="VQ862_000658"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:305..307,aa:Met,seq:cat)
     gene            348..420
                     /locus_tag="VQ862_000659"
     tRNA            348..420
                     /locus_tag="VQ862_000659"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:381..383,aa:Phe,seq:gaa)
     gene            440..510
                     /locus_tag="VQ862_000660"
     tRNA            440..510
                     /locus_tag="VQ862_000660"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:472..474,aa:Gly,seq:tcc)
     gene            546..619
                     /locus_tag="VQ862_000661"
     tRNA            546..619
                     /locus_tag="VQ862_000661"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:580..582,aa:Ile,seq:gat)
     gene            626..713
                     /locus_tag="VQ862_000662"
     tRNA            626..713
                     /locus_tag="VQ862_000662"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:660..662,aa:Ser,seq:gct)
     gene            complement(839..1774)
                     /locus_tag="VQ862_000663"
     CDS             complement(839..1774)
                     /locus_tag="VQ862_000663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000844514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional biotin--[acetyl-CoA-carboxylase]
                     synthetase/biotin operon repressor"
                     /protein_id="HET3115045.1"
                     /translation="MKSYQAVYQILSKETDYISGEKIAEKLSLSRTAIWKAIKRLEQE
                     GIEIDSIKNRGYKLMNGDLILPEILEENLPIKVSFKPETKSTQLDAKEAIDLGHEANT
                     LYLASYQTAGRGRFQRSFYSPQGGIYMTLHLKPNLPYDKLPSYTLLVAGAVYKAIKNL
                     TLIDVDIKWVNDIYLNNHKIGGILTEAMTSVETGLVTDIIIGVGINFTIKDFPQELKE
                     KAASLFKATAPITRNELIIEIWRAFFETPAEELLYLYKKQSFILGKEVTFTLEQKDYK
                     GLAKDISENGKLLVQCDNGKEIWLNSGEISLNSWK"
     gene            complement(1771..2631)
                     /locus_tag="VQ862_000664"
     CDS             complement(1771..2631)
                     /locus_tag="VQ862_000664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000959966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HET3115046.1"
                     /translation="MLVFSEYQTGTIDLALSFYGYEECTPNYSFGPAIRDTYVLHYIT
                     KGQGKFHYKGKIVDLKEGDFFLLKPEELTFYQADSKEPWAYYWLGITGGKAPDYFALS
                     QISDQSYLIQSETCHTQTTAKLISDIVRFAQITKSSELAQLHIMGQLHELMFHLGTIA
                     PNQKKKNISSTHQLYLECKRLIDSHYPQSLTIQDLAKELSVHRSYLSSVFKEFNTLSP
                     KEYLLYVRMHRARQLLENTQESIKVIAYSVGFSDPLHFSKAYKQYFNQTPSHTRKEYS
                     QYQLVRKATL"
     gene            2739..4901
                     /locus_tag="VQ862_000665"
     CDS             2739..4901
                     /locus_tag="VQ862_000665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000538915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HET3115047.1"
                     /translation="MGVRIENNLFYVESKNLSLIIENRNGYLLLKHLGKTIKNYKGSN
                     SVYERDHAFSGNPTATNRTFSLDTQRQIFGQHGLGDFRKPTIQVQHSVTEVTDFRFVE
                     AKILKGQNGPQGLPSPHSMDDTETLVLMLEDSKAQLSLTLYYTTFNNDATIASYSKLD
                     NNSNQEVVIHKDFSFMADFPAADYEIVTLQGAYAREKTVRRQQVEQGIFSISSNRGAS
                     GHAQTPALLLCEQGVTEDAGNVFAIQLMYSGNFEAFVQKNQLNEVRVAIGINPENFSW
                     KLAPEEYFETPVALVTHSDQGLTGISHESQNFVLKHIMLSEFSKKERPILINNWEATY
                     FDFQREKLLELADEAKKVGIELFVLDDGWFGNRFDDNRALGDWVVNEEKLGGSLESLI
                     SAIHERGLQFGLWLEPEMISVDSDLYRQHPDWAIQVPGYEHTYSRNQLVLNLANPQVV
                     EYLKSVLDQLLFYHDIDYIKWDMNRNITKLGNGLTYLETQMQSHQYMLGLYELVSYLT
                     EKHSHILFESCSGGGGRNDLGMMRYFPQVWASDNTDAIARLPIQYGSSYLYPTISMGA
                     HVSAVPNHQMGRMTPLETRGLVAMMGNLGYELDLTNLSDEEKATIANQVNLYKELRPV
                     VQLGQQYRLINPDTVSNEAAVQFNYGNQTIVTYVRVLSVVETMETTLKLKDLDEEGLY
                     KLQENGEVYSGAELMYAGLTVILSQGDFLSRQYIFRKL"
     gene            4993..6252
                     /locus_tag="VQ862_000666"
     CDS             4993..6252
                     /locus_tag="VQ862_000666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HET3115048.1"
                     /translation="MEWYKKIGLLATTGLALFGLGACSNYGKSADGTVTIEYFNQKKE
                     MTKTLEEITRDFEKENPKIKVKVVNVPNAGEVLKTRVLAGDVPDVVNIYPQSIELQEW
                     AKAGVFEDLSNKDYLKRVKNGYAEKYAVNEKVYNVPFTANAYGIYYNKDKFEELGLKV
                     PETWDEFEQLVKDIVAKGQTPFGIAGADAWTLNGYNQLAFATATGGGKEANQYLRYSQ
                     PNAIKLSDPIMKDDIKVMDILRINGSKQKNWEGAGYTDVIGAFARGDVLMTPNGSWAI
                     TAINEQKPNFKIGTFMIPGKEKGQSLTVGAGDLAWSISATTKHPKEANAFVEYMTRPE
                     VMQKYYDVDGSPTAIEGVKQAGEDSPLAGMTEYAFTDRHLVWLQQYWTSEADFHTLTM
                     NYVLTGDKQGMVNDLNAFFNPMKADVD"
     gene            6266..7132
                     /locus_tag="VQ862_000667"
     CDS             6266..7132
                     /locus_tag="VQ862_000667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000757171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HET3115049.1"
                     /translation="MKKVLQKYWAWAFVVIPLLLQAIFFYVPMFQGAFYSFTNWTGLT
                     YNYKFVGLNNFKLLFMDPKFMNAIGFTAIIAIAMVVGEIALGIFIARVLNSKIKGQTF
                     FRAWFFFPAVLSGLTVALIFKQVFNYGLPAIGNALHIEFFQTSLLGTKWGAIFAAVFV
                     LLWQGVAMPIIIFLAGLQSIPTEITEAARIDGATSKQVFWNIELPYLLPSVSMVFILA
                     LKGGLTAFDQVFAMTGGGPNNATTSLGLLVYNYAFKNNQFGYANAIAVILFFLIVVIS
                     IIQLRVSKKFEI"
     gene            7146..7979
                     /locus_tag="VQ862_000668"
     CDS             7146..7979
                     /locus_tag="VQ862_000668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HET3115050.1"
                     /translation="MKQDERKALIGKYILLILGSVLILVPLLATLFSSFKPTKDIVDN
                     FFGFPTNFTWDNFSRLLADGIGGYYWNSVVITVLSLLAVMIFIPMAAYSIARNMSKRK
                     AFTIMYTLLILGIFVPFQVIMIPITVMMSKLGLANTFGLILLYLTYAIPQTLFLYVGY
                     IKISIPESLDEAAEIDGANQFTTYFRIIFPMMKPMHATTMIINALWFWNDFMLPLLVL
                     NRDSKMWTLPLFQYNYAGQYFNDYGPSFASYVVGIISITIVYLFFQRHIISGMSNGAV
                     K"
     gene            7980..8060
                     /locus_tag="VQ862_000669"
                     /pseudo
     CDS             7980..8060
                     /locus_tag="VQ862_000669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            8337..9779
                     /gene="gtfA"
                     /locus_tag="VQ862_000670"
     CDS             8337..9779
                     /gene="gtfA"
                     /locus_tag="VQ862_000670"
                     /EC_number="2.4.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001122330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose phosphorylase"
                     /protein_id="HET3115051.1"
                     /translation="MPIQNKTMLITYSDSLGNNLKDLYDNLEEHFGDAIGGVHLLPFF
                     PSTGDRGFAPVDYDEVDSAFGDWEDVKHLGEKYYLMFDFMINHISRQSKYYKDYQEKH
                     EASEFKALFLNWDKFWPENRPTQSDVDLIYKRKDRAPKQEIVFEDGSVEHLWNTFGEE
                     QIDLDVTKEVTMEFIRKTIQHLASNGCDLIRLDAFAYAVKKLDTNDFFVEPDIWDLLD
                     KVRDIAAEYGTELLPEIHEHYSIQFKIADHDYYVYDFALPMVTLYTLYSSRTERLAKW
                     LKMSPMKQFTTLDTHDGIGVVDVKDILTDEEIDYASNELYKVGANVKRKYSSAEYNNL
                     DIYQINSTYYSALGDDDVKYFLARLIQAFAPGIPQVYYVGLLAGKNDLKLLEETKEGR
                     NINRHYYSNEEIAKEVQRPVVKALLNLFSFRNRSEAFDLEGTTEIETPTAHSIVIKRQ
                     NKDKSVTAVAEIDLQNQTYRVIENGVEVTF"
     gene            9917..11110
                     /locus_tag="VQ862_000671"
     CDS             9917..11110
                     /locus_tag="VQ862_000671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008293041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen ligase family protein"
                     /protein_id="HET3115052.1"
                     /translation="MKSIGFIEKLKGLSSKELILLGIILSIFLPFYLFVVVLCLYIIS
                     LIFTGDMKSILQKMGEHPMLLLFLSYSTVISILAQNWMGLVASVGMFLFTIFFLHYQS
                     ILSHKFFRLILQFVLFGSVLSAAFASLEHFQIVKKFNYAFLSPNMQVWHQNRAEVTFF
                     NPNYYGIICCFCIMIAFYLFTTTKLNWLKVFCVIAGFVNLFGLNFTQNRTAFPAIIAG
                     AIIYLFTTIKNWKAFWLSIGVFAIGLSFLFSSDLGVRMGTLDSSMEERISIWDAGMAL
                     FKQNPFWGEGPLTYMHSYPRIHAPYHEHAHSLYIDTILSYGIVGTILLVLSSVAPVRL
                     MMDMSQESGKRPIIGLYLSFLTVVAVHGIFDLALFWIQSGFIFLLVMCSIPLEHRMLV
                     SDMTD"
     gene            11797..13776
                     /locus_tag="VQ862_000672"
     CDS             11797..13776
                     /locus_tag="VQ862_000672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000742236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HET3115053.1"
                     /translation="MKKNRVFATAGLVLLAAGVLAACSSSKSSDSSAPKAYGYVYTAD
                     PETLDYLISSKNSTTVVTSNGIDGLFTNDNYGNLAPAVAEDWEVSKDGLTYTYKIRKG
                     VKWFTSDGEEYAEVTAKDFVNGLKHAADKKSEAMYLAENSVKGLADYLSGTSTDFSTV
                     GVKAVDDYTLQYTLNQPEPFWNSKLTYSIFWPLNEEFETSKGSDFAKPTDPTSLLYNG
                     PFLLKGLTAKSSVEFVKNEQYWDKENVHLDTINLAYYDGSDQESLERNFTSGAYSYAR
                     LYPTSSNYSKVAEEYKDNIYYTQSGSGIAGLGVNIDRQSYNYTSKTTDSEKVATKKAL
                     LNKDFRQALNFALDRSAYSAQINGKDGAALAVRNLFVKPDFVSAGEKTFGDLVAAQLP
                     AYGDEWKGVNLADGQDGLFNADKAKAEFAKAKKALEADGVQFPIHLDVPVDQASKNYI
                     SRIQSFKQSVETVLGVENVVVDIQQMTSDEFLNITYYAANASSEDWDVSGGVSWGPDY
                     QDPSTYLDILKTTSSETTKTYLGFDNPNSPSVVQVGLKEYDKLVDEAARETSDLNVRY
                     EKYAAAQAWLTDSSLFIPAMASSGAAPVLSRIVPFTGASAQTGSKGSDVYFKYLKLQD
                     KVVTKEEYEKAREKWLKEKAESNEKAQKELASHVK"
     gene            13843..15339
                     /locus_tag="VQ862_000673"
     CDS             13843..15339
                     /locus_tag="VQ862_000673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET3115054.1"
                     /translation="MKKYIFMRVLRSLVSIFLVTTLTYTIIYTLVPRKLIFKQDPNYN
                     KIATTADKRDNYENTVFERMGYIEYYDTKELQEKASSMDSSVTVEANATNKAIYEKYI
                     NQLGHGWTLGEFTESGQFYATREIPIFERVFHFYANLIDIDHTNKIQDPENPDLKRYL
                     RFENDPAIGWSLVGSGTKHKYLLYFNSQFPFVHQNFVNLNLGDSYPTYANTPVLQVIT
                     QGQGQTKTAQVQFPTGKKTSSVNIYSRTYKSPSQADSREVASYGKDDPYTATESNYQY
                     PSMIVSSAITGLIGLVLAYALAVPLGSAMARFKNTWIDSLSTGALTFLLALPTIALVY
                     IVRLIGSSIALPDSFPILGAGDWRSYVLPAVILGLLGAPGTAIWIRRYMIDLQSQDFV
                     RFARAKGLSEKEISNKHIFKNAMVPLVSGIPGAIIGVIGGATLTETVFAFPGMGKMLI
                     DSVKASNNSMVVGLVFIFTCISIFSRLLGDIWMTIIDPRIKLTEKGGK"
     gene            15339..16265
                     /locus_tag="VQ862_000674"
     CDS             15339..16265
                     /locus_tag="VQ862_000674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET3115055.1"
                     /translation="MSTIDKEKFQFVKRDDFASETIDAPAYSYWKSVFKQFMKKKSTV
                     VMLGILVAIILISFIYPMFSKFDFNDVSKVNDFSVRYIKPNAEHWFGTDSNGKSLFDG
                     VWFGARNSILISVIATVINLVIGVFVGGIWGISKSVDRVMMEVYNVISNIPPLLIVIV
                     LTYSIGAGFWNLIFAMSVTTWIGIAFMIRVQILRYRDLEYNLASRTLGTPTLKIVAKN
                     IMPQLVSVIVTTMTQMLPSFISYEAFLSFFGLGLPITVPSLGRLISDYSQNVTTNAYL
                     FWIPLTTLVLVSLSLFVVGQNLADASDPRTHR"
     gene            16274..17341
                     /locus_tag="VQ862_000675"
     CDS             16274..17341
                     /locus_tag="VQ862_000675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3115056.1"
                     /translation="MTKEKNVILTARDIVVEFDVRDKVLTAIRGVSLELVEGEVLALV
                     GESGSGKSVLTKTFTGMLEENGRIAQGSIDYRGQDLTALSSHKDWEQIRGAKIATIFQ
                     DPMTSLDPIKTIGSQITEVIVKHQGKTAKEAKELAIDYMNKVGIPDADRRFNEYPFQY
                     SGGMRQRIVIAIALACRPDVLICDEPTTALDVTIQAQIIDLLKSLQNEYHFTTIFITH
                     DLGVVASIADKVAVMYAGEIVEYGTVEEVFYDPRHPYTWSLLSSLPQLADDKGDLYSI
                     PGTPPSLYTDLKGDAFALRSDYAMQIDFEQKAPQFSVSETHWAKTWLLHEDAPKVEKP
                     AVIANLHDKIREKMGFAHLAD"
     gene            17352..18278
                     /locus_tag="VQ862_000676"
     CDS             17352..18278
                     /locus_tag="VQ862_000676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001291287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3115057.1"
                     /translation="MSEKLVEIKDLEISFGEGSKKFVAVKNANFFINKGETFSLVGES
                     GSGKTTIGRAIIGLNDTSNGDIIFDGQKINGKKSREQAAELIRRIQMIFQDPAASLNE
                     RATVDYIISEGLYNHRLFKDEEERKEKVQSIIREVGLLAEHLTRYPHEFSGGQRQRIG
                     IARALVMQPDFVIADEPISALDVSVRAQVLNLLKKFQKELGLTYLFIAHDLSVVRFIS
                     DRIAVIYKGVIVEVAETEELFNNPIHPYTQALLSAVPIPDPILERKKVLKVYDPSQHD
                     YETDKPSMVEIRPGHYVWANQAELARYQKGLN"
     gene            18769..19284
                     /locus_tag="VQ862_000677"
     CDS             18769..19284
                     /locus_tag="VQ862_000677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000512060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HET3115058.1"
                     /translation="MGILLTSLISLHQLKADKKRDVFRIGISQFITHQSLDATREGFV
                     DELAKQGYVEGENIEIDLQNAQGEQRNLKTISQQLAESSDVVLAIARPSAQSLANTTQ
                     TPPVIFSAVTDPVSAKLVESREHPGGNVTGTSDQSSDAISTQINLIKKVLPKAKTIGI
                     LYTQSEPNSVV"
     gene            19306..19707
                     /locus_tag="VQ862_000678"
     CDS             19306..19707
                     /locus_tag="VQ862_000678"
                     /inference="COORDINATES: protein motif:HMM:NF016292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3115059.1"
                     /translation="MKEKGFTVVEKTILDSNNVKAAAESLMAEVDMVFVPTDNIISST
                     METVKQVSIKHKVPVFGGSTEMIAVGDLYNYGTNYEELGRQTARMLIRVLKGEKPENI
                     AVELPEKLELHTNQEMADALGIDISKLEGKE"
     gene            19719..20596
                     /locus_tag="VQ862_000679"
                     /pseudo
     CDS             19719..20596
                     /locus_tag="VQ862_000679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001012086.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
     gene            20609..21412
                     /locus_tag="VQ862_000680"
     CDS             20609..21412
                     /locus_tag="VQ862_000680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000157668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HET3115060.1"
                     /translation="MASLLTLENIHKTFEAGTVNENHVLKGLDLEVEEGDFIYVIGGN
                     GAGKSTLMNILAGNLSVDEGDLLLAGKSIKNLSVRKRAKDIARVFQYPKMGTASRLTI
                     EENMAIALRRGQKRGLGWGVKEKDRIQFQEALKELNIGLENRLKVDTQYLSGGQRQAL
                     TLVMAALVKPKLLLLDEHTAALDPKTSQMVMDLTQKIVEHHQWTTLMITHDMNHAIEY
                     GNRLIMLYQGKIVVDVKGEEKKHLTVEDLMHLFQKNSGQSLVSDELVLG"
     gene            complement(21445..22155)
                     /gene="treR"
                     /locus_tag="VQ862_000681"
     CDS             complement(21445..22155)
                     /gene="treR"
                     /locus_tag="VQ862_000681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trehalose operon repressor"
                     /protein_id="HET3115061.1"
                     /translation="MKKYQQLFKQIQETIQNETYAVGDFLPSEHDLMEQYQVSRDTVR
                     KALSLLQEEGLIKKIRGQGSQVVKEETVNFPVSNLTSYQELVKELGLRSKTNVVSLDK
                     IIIDKKSSLITGFPEFRMVWKVVRQRVVDDLVSVLDTDYLDMELIPNLTRQIAEQSIY
                     SYIENGLKLLIDYAQKEITIDHSSDRDKILMDIGKDPYVVSIKSKVYLQDGRQFQFTE
                     SRHKLEKFRFVDFAKRKK"
     gene            22340..24307
                     /gene="treP"
                     /locus_tag="VQ862_000682"
     CDS             22340..24307
                     /gene="treP"
                     /locus_tag="VQ862_000682"
                     /EC_number="2.7.1.201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system trehalose-specific EIIBC component"
                     /protein_id="HET3115062.1"
                     /translation="MGKFEQEAKDLLQAIGGKENVTAVTHCATRMRFVLGDDKKANVK
                     AIESIPAVKGTFTNAGQFQVIIGNDVPIFYNDFTAVSGIEGVSKEAAKSAAKSNQNVV
                     QRVMTTLAEIFTPIIPALIVGGLILGFRNVLEGVHWSMLDGKTITESSQFWAGVNHFL
                     WLPGEAIFQFLPVGITWSVSRKMGTSQILGIVLGICLVSPQLLNAYAVASTPAADIAA
                     NWVWNFGYFTVNRIGYQAQVIPALLAGLSLSYLEIFWRKHIPEVISMIFVPFLSLIPA
                     LILAHTVLGPIGWTIGQGLSSVVLAGLTGPVKWLFGAIFGALYAPFVITGLHHMTNAI
                     DTQLIADAGGTALWPMIALSNIAQGSAVFAYYFMHRHDEREAQVSLPATISAYLGVTE
                     PALFGVNVKYIYPFVAGMTGSALAGMLSVTFNVTAASIGIGGLPGILSIQPQYMLPFA
                     GTMLVAIVVPMLLTFFFRKAGLFTKTEGDTNLQAEFVAQEEAEFVNHEPVELTSVEII
                     SPLTGQVKELSQATDPIFASGVMGQGLVIEPSQGELTSPVNGTVTVLFPTKHAIGIVS
                     DEGVELLIHIGMDTVGLDGKGFESLVVQGDHVTVGQQLIRFDMDVIKAAGLVTETPVI
                     ITNQDAYTATIPGTYPTTIQAGASLMVATRI"
     gene            24485..26110
                     /gene="treC"
                     /locus_tag="VQ862_000683"
     CDS             24485..26110
                     /gene="treC"
                     /locus_tag="VQ862_000683"
                     /EC_number="3.2.1.93"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000171230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha,alpha-phosphotrehalase"
                     /protein_id="HET3115063.1"
                     /translation="MTLDKGKVVYQIYPKSYKDTTENGIGDFRGIIGKIPYLAKLGVD
                     MVWLNPFYPSPQRDNGYDISDYMAVDPLFGDMADFEEMVCIGKEHKIDFMLDMVLNHC
                     STEHEWFQKALAGDKYYQDFFFIQDQPTDWQSKFGGSAWAPFGDTGKYYLHLFDETQA
                     DLNWRNPNVRKELFKVVNFWRDKGVKGFRFDVINLIGKDEVSVDCPENEGKPAYTDKP
                     IVHNYLRMMNQATFGSDDSFMTVGEMSSTTMENCVLYSSPDRQELSMTFNFHHLKVDY
                     KDGQKWTLAPFDFEELKSLYHSWGKEMSDKDGWSALFWNNHDQPRALNRFVDIQNFRK
                     EGATMLAASIHLSRGTPYIYMGEEIGMIDPDYYSMADYVDVESLNAYQMLLEEGKSQQ
                     EAFQIIQAKSRDNSRIPMQWDASENAGFSTGTPWLKAGKSYKYINVENEIQGPIFTFY
                     QDLIRLRKEMPIISEGSYKPAFEDSKQVYAFERQFEDQKLLVLNNFYAKEVEIDLPAV
                     YQNGQILISNYEDAEVSEKILLKPYQTLAIYVN"
     gene            26252..26500
                     /locus_tag="VQ862_000684"
     CDS             26252..26500
                     /locus_tag="VQ862_000684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000364981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YneF family protein"
                     /protein_id="HET3115064.1"
                     /translation="MDLLLAIVLIVLAFLGGALGGMYLVRKQIEKEFADNPRLNAEAV
                     RTLLSANGQKPSEAKVQQVYHQIIRQQKAALANNKKKK"
     gene            26707..27501
                     /gene="racE"
                     /locus_tag="VQ862_000685"
     CDS             26707..27501
                     /gene="racE"
                     /locus_tag="VQ862_000685"
                     /EC_number="5.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000370386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate racemase"
                     /protein_id="HET3115065.1"
                     /translation="MDNRPIGFLDSGVGGLTVVRELMRQLPHEEIVYIGDSARAPYGP
                     RPAEQIREYTWQLVNFLLTKDVKMIVIACNTATAVVWEEIKAQLDIPVLGVILPGASA
                     AIKSSQGGKIGVIGTPMTVQSDIYRQKIHDLDPDLQVESLACPKFAPLVESGALSTSV
                     TKKVVYETLRPLVGKVDSLILGCTHYPLLRPIIQNVMGPKVQLIDSGAECVRDISVLL
                     NYFEINRGRDAGPLHHRFYTTASSQSFAQIGEEWLEKEIHVEHVEL"
     gene            27498..28469
                     /locus_tag="VQ862_000686"
     CDS             27498..28469
                     /locus_tag="VQ862_000686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000182414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-triphosphate diphosphatase"
                     /protein_id="HET3115066.1"
                     /translation="MTNKIYEYKDDQDWYVGSYSIFGGVNSLSDYQTDFPLFEFSKIF
                     GDEEYGFPLSVTVLRYGSTYRLFSFVVDMLNQEMGRNLEVIQRHGALLLVENGQLLYV
                     ELPKEGVNVHDFFETSKVRETLLIATRNEGKTKEFRAIFDKLGYDVENLNDYPDLPEV
                     AETGMTFEENARLKAETISQLTGKMVLADDSGLKVDVLGGLPGVWSARFAGVGATDRE
                     NNAKLLHELAMVFELKDRSAQFHTTLVVASPNKESLVVEADWSGYINFEPKGENGFGY
                     DPLFLVGETGESSAELTLEEKNSQSHRALAVKKLLEVFPSWQSKPSL"
     gene            28445..28966
                     /locus_tag="VQ862_000687"
     CDS             28445..28966
                     /locus_tag="VQ862_000687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001118598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HET3115067.1"
                     /translation="MAKQTIIVMSDSHGDSLIVEEVRDRYVGKVDAVFHNGDSELRPD
                     SPLWEGIRVVKGNMDFYAGYPERLVTELGSTKIIQTHGHLFDINFNFQKLDYWAQEEE
                     AAICLYGHLHVPSAWMEGKILFLNPGSISQPRGTIRECLYARVEIDDSYFKVDFLTRD
                     HEVYPGLSKEFSR"
     gene            28963..29424
                     /locus_tag="VQ862_000688"
     CDS             28963..29424
                     /locus_tag="VQ862_000688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000560721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HET3115068.1"
                     /translation="MIAKEFETFLLGQEETFLTPAKNLAVLIDTHNADHATLLLSQMT
                     YTRVPVVTDEKQFVGTIGLRDIMAYQMEHDLSQEIMADTDIVHMTKTDVAVVSPDFTI
                     TEVLHKLVDESFLPVVDTEGIFQGIITRKSILKAVNALLHDFSKEYEIRCQ"
     gene            29415..30155
                     /gene="xerD"
                     /locus_tag="VQ862_000689"
     CDS             29415..30155
                     /gene="xerD"
                     /locus_tag="VQ862_000689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004245562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific tyrosine recombinase XerD"
                     /protein_id="HET3115069.1"
                     /translation="MPMRDRISAFLEEKQGLSVNSKQSYKYDLEQFLDMVGERISETS
                     LKIYQAQLANLKISAQKRKISACNQFLYFLYQKGEVDSFYRLELAKQAEKKTEKPEIL
                     YLDSFWQESDHPEGRLLALLILEMGLLPSEILAIKVADINLDFQVLRISKASQQRIVT
                     IPTALLSELEPLMGQTYLFERGGKPYSRQWAFRQLESFVKEKGFPSLSAQVLREQFIL
                     RQIENKVDLYEIAKKLGLKTVLTLEKYR"
     gene            30155..30883
                     /locus_tag="VQ862_000690"
     CDS             30155..30883
                     /locus_tag="VQ862_000690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000351912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein A"
                     /protein_id="HET3115070.1"
                     /translation="MDIKLKDFEGPLDLLLHLVSKYQMDIYDVPITEVIEQYLAYVST
                     LQAMRLEVTGEYMVMASQLMLIKSRKLLPKVAEVTDLGDDLEQDLLSQIEEYRKFKLL
                     GEHLEAKHQERAQYYSKAPTELIYEDAELVHDKTTIDLFLAFSNILAKKKEEFAQNHT
                     TILRDEYKIEDMMIIVKESLIGRDQLRLQDLFKEAQNVQEVITLFLATLELIKTQELI
                     LVQEESFGDIYLMEKKEESQVPQS"
     gene            30902..31471
                     /locus_tag="VQ862_000691"
     CDS             30902..31471
                     /locus_tag="VQ862_000691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000105309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein B"
                     /protein_id="HET3115071.1"
                     /translation="MSTLAKIEALLFVAGEDGIRVRQLAELLSLPPTGIQQSLGKLAQ
                     KYEKDPDSSLALIETSGAYRLVTKPQFAEILKEYSKAPINQSLSRAALETLSIIAYKQ
                     PITRIEIDAIRGVNSSGALAKLQAFDLIKEDGKKEVLGRPNLYVTTDYFLDYMGINHL
                     EELPVIDELEIQAQESQLFGERIEEDENQ"
     gene            31458..32180
                     /locus_tag="VQ862_000692"
     CDS             31458..32180
                     /locus_tag="VQ862_000692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HET3115072.1"
                     /translation="MRINKYIAHAGVASRRKAEELIKQGLVTVNGQVVRELATTIKSG
                     DKVEVEGQPIYNEEKVYYLLNKPRGVISSVTDDKGRKTVVDLLPNVKERIYPVGRLDW
                     DTSGVLILTNDGDFTDEMIHPRNEIDKVYVARVKGVANKDNLRPLTRGLEIDGKKTKP
                     AVYEILKVDPVKNRSVVQLIIHEGRNHQVKKMFEAVGLQVDKLSRTRFGHLDLTGLRP
                     GESRRLNKKEISQLHTMAVTKK"
     gene            32180..32422
                     /gene="yidD"
                     /locus_tag="VQ862_000693"
     CDS             32180..32422
                     /gene="yidD"
                     /locus_tag="VQ862_000693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertion efficiency factor
                     YidD"
                     /protein_id="HET3115073.1"
                     /translation="MKRILIAPVRFYQRFISPVFPPSCRFELTCSNYMIQAIEKHGFK
                     GVLMGLSRILRCHPWSKTGKDPVPDRFSLKRNQEGE"
     gene            complement(32647..33612)
                     /locus_tag="VQ862_000694"
     CDS             complement(32647..33612)
                     /locus_tag="VQ862_000694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000858258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siderophore ABC transporter substrate-binding
                     protein"
                     /protein_id="HET3115074.1"
                     /translation="MKTSLKLYFTALVASFLLLLGACSTNSSTSQTETSSSAPTEVTI
                     KSSLDEVKLSKVPEKIVTFDLGAADTIRALGFEKNIVGMPTKTVPTYLKDLVGTVKNV
                     GSMKEPDLEAIAALEPDLIIASPRTQKFVDKFKEIAPTVLFQASKDDYWTSTKANIES
                     LASAFGETGTQKAKEELAKLDKSIQEVATKNESSDKKALAILLNEGKMAAFGAKSRFS
                     FLYQTLKFKPTDTTFEDSRHGQEVSFESVKEINPDILFVINRTLAIGGDNSSNDGVLE
                     NALIAETPAAKNGKIIQLTPDLWYLSGGGLESTKLMIEDIQKALK"
     gene            complement(33708..34460)
                     /locus_tag="VQ862_000695"
     CDS             complement(33708..34460)
                     /locus_tag="VQ862_000695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000764290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HET3115075.1"
                     /translation="MKLENIDKSIQKQDILQGISLEVSPQKLTAFIGPNGAGKSTLLS
                     IMSRLTKKDQGVLSIKGREIESWNSQELAQELTILKQKINYQAKLTVEELVSFGRFPY
                     SRGRLRSEDWEKIRETLNYLELTNLKDRYINSLSGGQLQRVFIAMVLAQDTDFILLDE
                     PLNNLDIKQSVSMMQILRRLVEELGKTIIIVLHDINMASQYADEIVAFKDGQVFSKGR
                     TDQIMQADLLSQLYEIPITLADINNKKICIYS"
     gene            complement(34457..35413)
                     /locus_tag="VQ862_000696"
     CDS             complement(34457..35413)
                     /locus_tag="VQ862_000696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001193667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HET3115076.1"
                     /translation="MQTKSKHTKLFWILIILAIGACLLYFWPITHLSAFAWKLRSQKI
                     IVYLLVAIATGISTISFQTLTENRFLTPSILGIESFYVLLQTLLLVFESKFLQLGKSP
                     ILEFLVLLLVQSLFFLALQGYLKTLMKQDLVFILLICLALRSLFRNISTFLQVLMDPN
                     EYDKLQNSLFASFQHLNTSILAIGSLIILALTIFFFRKAVVLDVLHLQRETAQILGLD
                     VEKEQKELLWGIVLLTSTATALVGPMAFFGFMLANLTYLIVKDYQHKLLFIVAILVGF
                     ISLTLGQALIERVFALEIRISMIIESVGGFLFFILLYRRARQ"
     gene            complement(35403..36362)
                     /locus_tag="VQ862_000697"
     CDS             complement(35403..36362)
                     /locus_tag="VQ862_000697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET3115077.1"
                     /translation="MKLSHYLIGLLLLLVFLSISIGTSDFSWGKLFDFDQQTWLLFQE
                     SRLPRTISILLTASSMSMAGLLMQTITQNQFAAPSTVGTTEAAKLGMVLSLFVFPSAS
                     LTQKMLFAFVSSIVFTLFFLAFMTIFTVKERWMLPLIGIIYSGIIGSVTEVIAYRFNL
                     VQSMTAWTQGSFSMIQTHQYEWLFLGLIILITVWKLSQTFTIMNLGKETSEGLGISYS
                     LLEKLALFLVALTTSVTMITVGGLPFLGVIVPNLVRKRYGDNLSQTKLMVALVGANLV
                     LACDILSRVLIRPYELSVSLLLGIIGSLVFILLLWRGGRKDAD"
     gene            complement(36785..37486)
                     /gene="galE"
                     /locus_tag="VQ862_000698"
     CDS             complement(36785..37486)
                     /gene="galE"
                     /locus_tag="VQ862_000698"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HET3115078.1"
                     /translation="MTKTILVTGGTSYIGSHTVKALLNAGYQVHVLDNLSTGNRAAVD
                     SRASFKELDVYDASALKAYLEENQIDAVLHCAGEIVVSESIENPSKYFTANVAGMNQV
                     LKVLSEVGIQKIMFSSTASLYGNNCIDKPVTEDTLLDPVNPYAETKLMGERMIYWMAN
                     RYDWKYVIFRYFNVAGAEMDASNGLRVKNPTHIIPNINKTALGQHDSLKIFGDDYDTR
                     DGSCIRDYIYVLDLA"
     gene            37888..38952
                     /gene="pepA"
                     /locus_tag="VQ862_000699"
     CDS             37888..38952
                     /gene="pepA"
                     /locus_tag="VQ862_000699"
                     /EC_number="3.4.11.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamyl aminopeptidase"
                     /protein_id="HET3115079.1"
                     /translation="MTTLFSKIKEVTELAAVSGHEAPVRAYLREKLTPHVDEVVTDGL
                     GGIFGIKHSEAVDAPRVLVASHMDEVGFMVSEIKPDGTFRVVEIGGWNPMVVSSQRFK
                     LLTRDGHEIPVISGSVPPHLTRGKGGPTMPAIADIVFDGGFADKDEAESFGIRPGDTI
                     VPDSSAILTANEKNIISKAWDNRYGVLMVSELAEALSGQKLGNELYLGSNVQEEVGLR
                     GAHTSTTKFDPEVFLAVDCSPAGDVYGGQGKIGDGTLIRFYDPGHLLLPGMKDFLLTT
                     AEEAGIKYQYYCGKGGTDAGAAHLKNGGVPSTTIGVCARYIHSHQTLYAMDDFLEAQA
                     FLQALVKKLDRSTVDLIKHY"
     gene            38974..39270
                     /locus_tag="VQ862_000700"
     CDS             38974..39270
                     /locus_tag="VQ862_000700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000230158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HET3115080.1"
                     /translation="MAEPNLESLIKDLYNHARHDLSEDLVAALLETAKKLPTTNEQLQ
                     AVRLSGLVNRELLLNPKHPAPELLNLARFIKREEAKYRGTATSALMYEELFKML"
     gene            39952..40395
                     /locus_tag="VQ862_000701"
     CDS             39952..40395
                     /locus_tag="VQ862_000701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000655204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HET3115081.1"
                     /translation="MKDGHLLAHHIRLLNGRIFQKLLSQDPEALYRGEQGKILAVLWN
                     SETGCATATDIALATGLANNTLTTMIKKLEEQKLVIVSPCGKDKRKKYLVLTELGKSQ
                     KEVGHRVSQKLDTIFYKGFSEEEIHQFEGFQERILANLKEKGNEV"
     gene            40399..41163
                     /locus_tag="VQ862_000702"
     CDS             40399..41163
                     /locus_tag="VQ862_000702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000043863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nuclear transport factor 2 family protein"
                     /protein_id="HET3115082.1"
                     /translation="MSQQVKNAHNLYIHAIQDGRVAEAQAQSVGDTYIQHSTGVPDGK
                     EGFAAFFADFFERHPERQIKIVRTIEDGNLVFVHVHQYLNGGEAQWVTTDTFRADENG
                     RIVEHWDVIDYYRTPENDQLDQIFGDFEIKDLDKKAENKKLVRRFLTEIFQNGELEQW
                     SDYVADDLIQHNHEIGQGSAAYKNYVAEYSVTFDFVFQLLGQGNYVVSYGQTQIDGVA
                     YAQYDIFRLENGKIVEHWDNKEVMPKVEDLTNRGKF"
     gene            41178..41906
                     /locus_tag="VQ862_000703"
     CDS             41178..41906
                     /locus_tag="VQ862_000703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3115083.1"
                     /translation="MIEYKNVALRYTEKDVLRDVNLQIEDGEFMVLVGPSGSGKTTML
                     KMINRLLEPTDGNIYMDGKRIKDYDERELRLSTGYVLQAIALFPNLTVAENIALIPEM
                     KGWSKEEITKKTEELLAKVGLPVAEYGHRLPSELSGGEQQRVGIVRAMIGQPKIFLMD
                     EPFSALDAISRKQLQVLTKELHKEFGMTTIFVTHDTDEALKLADRIAVLQDGEIRQVA
                     NPETILKVPATDFVADLFGGSVHD"
     gene            41899..43419
                     /locus_tag="VQ862_000704"
     CDS             41899..43419
                     /locus_tag="VQ862_000704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate-binding
                     protein"
                     /protein_id="HET3115084.1"
                     /translation="MTNLIATFQDRFSDWLTALSQHLQLSLLTLLLAILLAIPLAVFL
                     RYHEKLADWVLQIAGIFQTIPSLALLGLFIPLMGIGTLPALTALVIYAIFPILQNTIT
                     GLKGIDPSLQEAGIAFGMTRWERLKKFEIPLAMPVIMSGIRTAAVLIIGTATLATLIG
                     AGGLGSFILLGIDRNNASLILIGALSSAVLAIAFNFLLKVMEKAKLRTIFSGFALVAL
                     LLGLSYSPALLAQKEKENLIIAGKIGPEPEILANMYKLLIEENTSMTATVKPNFGTTS
                     FLYEALKKGDIDIYPEFTGTVTESLLQPSPKVSHEPEQVYQVARDGIAKQDHLAYLKP
                     MSYQNTYAVAVPKKIAQEYGLKTISDLKKVEGQLKAGFTLEFNDREDGNKGLQSMYGL
                     NLNVATMQPALRYQAIQSGDIQITDAYSTDAELERYDLQVLEDDKQLFPPYQGAPLMK
                     EALLKKHPELERVLNTLAGKITESQMSQLNYQVGVEGKSAKQVAKEFLQEQGLLKK"
BASE COUNT        12539 a         8076 c         9794 g        13024 t
ORIGIN      
        1 gcggtgtagc tcagctggct agagcgtccg gttcataccc gggaggtcgg gggttcgatc
       61 cccttcgccg ctataatgat cttgtcggac ctttagctca gctggttaga gctctcggct
      121 cataaccgag tggtcgtagg ttcaagtcct acaaggtcca tttgaatatt ggaggattac
      181 ccaagtccgg ctgaagggaa cggtcttgaa aaccgtcagg cgtgtaaaag cgtgcgtggg
      241 ttcgaatccc acatcctcct tttatattaa cgcgggatgg agcagctcgg tagctcgtcg
      301 ggctcataac ccgaaggtcg taggttcaaa tcctgctccc gcaataaggc tcggtagctc
      361 agttggtaga gcaatggatt gaagctccat gtgtcggcgg ttcgattccg tctcgcgcca
      421 ttttattgat agtatttatg cgggtgtagt ttagtggtaa aactacagcc ttccaagctg
      481 ttgtcgcgag ttcgattctc gtcacccgct ttgaactttg ttcaaattac caagtttttt
      541 aacttgggcg cgtagctcag ttggttagag cgcacgcctg ataagcgtga ggtcggtggt
      601 tcgagtccac tcgtgcccat taattggaga attactcaag aggctgaaga ggacggtttg
      661 ctaaatcgtt aggtcgggta actggcgcaa gggttcgaat cccttattct ccgttttaat
      721 gagagtctgt aactctcttt tttattttta gagccaataa aacttcagat ccgtaaaact
      781 taattgaatt actaatctga agttattttt atatcgttta tattataatt gtgttatttt
      841 acttccaact attgagagaa atttcgccac tatttagcca gatttctttt ccgttatcac
      901 attgaactaa aagttttcca ttttctgaga tgtctttagc aagtcccttg tagtcttttt
      961 gctctagtgt gaaagtgact tcttttccta gaatgaatga ctgttttttg tataggtata
     1021 atagctcttc tgctggtgtt tcgaagaaag cacgccagat ttctatgatc aattcattcc
     1081 ttgttatagg agctgtagct ttaaataagc tggcagcttt ttcttttaat tcctgaggga
     1141 agtctttaat agtgaaattg atacctactc caataatgat atctgtgact aagccagttt
     1201 ctacagaggt cattgcttca gtaaggattc ctccaatttt atgattgttt agatagatat
     1261 cattgaccca ttttatgtcg acatctatta aagttaggtt cttaatggct ttgtagacag
     1321 ctccagctac aagtagtgtg taggatggta atttgtcata ggggagattt ggtttaagat
     1381 ggagtgtcat ataaatacca ccttgtggtg agtagaagga acgttgaaaa cggcctcggc
     1441 ctgctgtttg ataggaagct agatagaggg tatttgcttc atggcctaaa tcaattgctt
     1501 cttttgcatc tagttgtgtt gattttgttt cgggtttaaa gctgacttta attggaagat
     1561 tttcttctag aatctctgga agaataaggt caccattcat cagtttatat cctctatttt
     1621 tgatactatc aatttcaatg ccttcttgtt ctagtcgctt gatggctttc caaattgctg
     1681 ttcggcttag ggatagtttt tctgcgattt tttctccgct gatatagtcg gtttctttag
     1741 ataggatttg gtagacagct tggtaggatt tcataatgtt gcctttctta ctagttggta
     1801 ttgagagtat tcttttcttg tatgacttgg agtctgatta aagtattgtt tataagcttt
     1861 cgaaaaatgg agtggatctg aaaaacctac cgagtatgca attaccttga tggactcttg
     1921 ggtattttcg agaagttgtc tagctcggtg cattcgaacg tagagtaggt attctttggg
     1981 tgataaggta ttaaattctt tgaatacgct tgataagtag cttctgtgaa cggatagttc
     2041 ttttgctaaa tcttgaattg taagtgattg aggatagtgg ctatcaatta atcgtttgca
     2101 ttcaagatag agttggtggg ttgatgaaat attctttttt ttctgattgg gagcaatagt
     2161 tcccagatga aacatcagtt catgaagttg tcccatgata tggagttgag ctaattcact
     2221 tgattttgta atctgagcga agcggacaat gtctgagatg agttttgcag tagtctgggt
     2281 atgacaagtt tcagattgga tgagatagga ttgatcagaa atttgggaaa gagcaaaata
     2341 atcaggggct ttccctccag tgattcctaa ccagtagtag gcccaaggtt ctttactatc
     2401 tgcttgataa aaggttagtt cctctggttt taatagaaag aaatctcctt cttttaaatc
     2461 aacaatttta cccttgtaat gaaattttcc ttgtccttta gtaatgtaat gtagaacgta
     2521 tgtatcacga atggctggac caaaagagta attaggtgtg cattcctcat atccataaaa
     2581 gcttagggca aggtcgattg ttccagtctg gtattctgaa aaaactaaca tgtgctacct
     2641 cctacctaac attttaccat attcttgaga catttttcta ttttggaaag cgatttcagg
     2701 tgataaaata taatcaataa agtgatgagg tgaagtaaat gggagttagg atagagaata
     2761 atctatttta tgttgagagt aaaaatctaa gtttgattat tgaaaatcga aatggctact
     2821 tacttttgaa acatttagga aagactatta agaactataa aggttccaat agtgtttatg
     2881 aacgagacca tgccttttca ggaaatccaa cggctactaa tcgaaccttt agtttagata
     2941 ctcagcgaca gatttttgga caacatggct taggagattt taggaaacca accatacagg
     3001 ttcagcatag tgtaactgaa gtaacagact ttcgatttgt agaagcaaag attttaaaag
     3061 gtcagaatgg tccacagggc ttaccttctc cacatagcat ggacgataca gagactcttg
     3121 tcttaatgtt agaagattct aaggctcaac ttagtctgac tttgtattat actactttta
     3181 ataatgatgc gactattgct agctacagta aattagataa taatagtaat caggaagttg
     3241 tcatccataa agatttttct tttatggctg attttccagc tgcagattac gaaatagtaa
     3301 ctctgcaggg tgcttatgct cgtgaaaaga ctgttagacg tcaacaggta gaacaaggaa
     3361 tcttttcgat tagttcaaac cgaggtgctt ctggtcatgc tcaaacacca gctcttctac
     3421 tatgcgaaca aggagtcaca gaggatgctg ggaatgtgtt tgctattcaa ctaatgtata
     3481 gtggcaactt tgaagctttt gttcaaaaaa atcaattgaa tgaagttcgg gtggctattg
     3541 gcattaatcc agaaaacttt tcttggaagt tagctcctga ggaatacttt gaaacaccgg
     3601 tagctttagt gactcattca gatcagggat taactggtat tagtcatgaa agtcagaatt
     3661 ttgtactgaa gcacattatg ctaagtgaat tttctaaaaa agaacgtcca attctaatca
     3721 ataactggga agctacttac tttgactttc agagagaaaa actgttagag ttagcagatg
     3781 aagctaagaa agttggcatt gaactttttg tattagatga tggttggttt ggcaatcgtt
     3841 ttgatgataa tcgtgcttta ggtgattggg ttgttaatga ggaaaaactg ggtggaagtc
     3901 tagaaagtct gatttcagct atccatgaaa gaggtttgca gtttggactt tggttagaac
     3961 ccgaaatgat ttctgtagat agtgatttgt atcgtcaaca tcctgactgg gctattcagg
     4021 ttcctggcta tgagcatact tattctcgga atcaattagt acttaatctt gccaatcctc
     4081 aggtagtaga atacttgaaa agtgtcttag atcaactcct attttatcat gatattgatt
     4141 acattaaatg ggatatgaac cgcaatatca ctaagctagg gaatggatta acttatctag
     4201 agacacagat gcaatctcat cagtacatgc tggggcttta tgaactcgtt tcttatctga
     4261 cagagaagca cagccatatt ctctttgagt cctgctctgg tggtggtgga cgaaatgatc
     4321 ttggtatgat gcgctatttc ccacaagtct gggctagtga taatactgat gccattgcac
     4381 gtttaccaat tcaatacggt tcatcctatc tctatccaac catttctatg ggggctcatg
     4441 tgtcagcagt accgaatcat cagatgggac gaatgacacc attagaaaca cgtggccttg
     4501 tagcaatgat gggaaatttg ggctatgaac ttgatttgac aaatttatca gatgaagaga
     4561 aagctacgat tgctaatcag gtgaacttgt ataaagaatt acgaccagta gttcagttag
     4621 gacagcagta tagactaatt aatcctgata ctgtatccaa tgaagcagct gtacaattta
     4681 attacggaaa tcaaacgatt gtaacctacg ttcgcgtttt atctgttgta gagaccatgg
     4741 aaacaacttt aaaattaaaa gatttggatg aagagggact atataaatta caggaaaatg
     4801 gcgaagttta ctcaggtgca gaactaatgt atgcgggctt aactgttatc ttatcccaag
     4861 gagatttttt gagtagacag tatattttta gaaaactatg atatgtactg accccaaaag
     4921 ttagatttat tctgtctaac ttttggggtg cagttcaata agggtgtata aatttataaa
     4981 ggaggctttc taatggaatg gtataaaaaa atcggacttc ttgcaactac aggtttagct
     5041 ttgtttgggc tcggcgcttg ctccaactat ggtaaatctg cggatggcac agtgaccatc
     5101 gagtatttca accagaaaaa agaaatgacc aaaaccttgg aagaaatcac tcgtgatttt
     5161 gagaaggaaa accctaagat caaggtcaaa gtcgtcaatg taccaaatgc tggtgaagta
     5221 ttgaagacac gcgttctcgc aggagatgtg cctgatgtgg tcaatattta cccacagtcc
     5281 atcgaactgc aagaatgggc aaaagcaggt gtttttgaag atttgagcaa caaagactac
     5341 ctgaaacgcg tgaaaaatgg ctacgctgaa aaatatgctg taaacgaaaa agtttacaac
     5401 gttcctttta cagctaatgc ttatggaatt tactacaaca aagataaatt cgaagaactg
     5461 ggcttgaagg ttcctgaaac ctgggatgaa tttgaacagt tagtcaaaga tatcgttgct
     5521 aaaggacaaa caccatttgg aattgcaggt gcagatgctt ggacactcaa tggttacaat
     5581 caattagcct ttgcgacagc aacaggtgga ggaaaagaag caaatcaata ccttcgttat
     5641 tctcaaccaa atgccattaa attgtcggat ccgattatga aagatgatat caaggtcatg
     5701 gacatccttc gcatcaatgg ctctaagcaa aagaactggg aaggtgctgg ctataccgat
     5761 gttatcggag ccttcgcacg tggggatgtc ctcatgacac caaatgggtc ttgggcgatc
     5821 acagcgatta atgaacaaaa accgaacttt aagattggga ccttcatgat tccaggaaaa
     5881 gaaaaaggac aaagcttaac cgttggtgcg ggagacttgg catggtctat ctcagccacc
     5941 accaaacatc caaaagaagc caatgccttt gtggaatata tgacccgtcc agaagtcatg
     6001 caaaaatact acgatgtgga cggatctcca acagcgatcg aaggggtcaa acaagcagga
     6061 gaagattcac cgcttgctgg tatgaccgaa tatgccttta cggatcgtca cttggtctgg
     6121 ttgcaacaat actggaccag tgaagcagac ttccatacct tgaccatgaa ctatgtcttg
     6181 accggtgata aacaaggcat ggtcaatgat ttgaatgcct tctttaaccc gatgaaagcg
     6241 gatgtggatt aggagtagag agactatgaa aaaagtatta caaaaatatt gggcatgggc
     6301 ttttgtggtc atccccctct tgttacaagc aattttcttc tatgtgccga tgtttcaagg
     6361 agccttttac agttttacca actggacagg attgacttat aactacaaat ttgttggctt
     6421 aaacaacttt aagctcctct tcatggatcc aaaattcatg aatgcgattg gctttaccgc
     6481 aatcattgcg attgccatgg tggttggtga gattgcactc gggatcttca ttgcgcgtgt
     6541 cttgaattct aaaatcaaag gccaaacctt cttccgtgct tggttcttct tcccagctgt
     6601 tttatctggt ttgacagtgg ctttgatctt caagcaagtc ttcaactacg gtcttccagc
     6661 gattggaaat gcccttcata ttgaattttt ccaaaccagt cttttaggga ctaagtgggg
     6721 agcaatcttt gcggctgtct ttgtccttct ttggcaaggg gtggctatgc ccatcatcat
     6781 cttcctagct ggtttgcaat ctattccaac tgagattaca gaggcagcaa ggattgatgg
     6841 tgcgactagc aagcaagttt tctggaacat tgaattgcct tacttgctac caagtgtctc
     6901 tatggtcttt atcctagccc taaaaggtgg gctgactgcc tttgaccaag tctttgccat
     6961 gaccggtggt ggtccaaaca atgccacaac ctcacttggg ctcttggttt ataactatgc
     7021 ctttaaaaac aaccaattcg gttatgccaa tgccattgcc gtaatcttgt tcttcttaat
     7081 tgtagtgatt tcgatcatcc aattgagagt atctaagaaa tttgaaattt aagaggagaa
     7141 gcatgatgaa acaagatgaa agaaaagccc tgattggcaa atacattcta ttgattctag
     7201 gatcggttct gattttagtg ccgctccttg ctaccctctt tagttccttc aaacccacta
     7261 aggatattgt agataatttc tttggctttc caaccaactt cacatgggac aactttagcc
     7321 gtctcttagc tgatgggatt ggaggctatt attggaactc tgtcgtcatc actgtcttgt
     7381 ctttacttgc agtaatgatc tttatcccta tggcagccta ctccatcgct cgcaatatga
     7441 gtaaaagaaa agcctttacc atcatgtata ccctcttaat cctcggaatc ttcgtacctt
     7501 tccaagtcat catgattccg attacggtta tgatgagtaa actcggtttg gctaatacct
     7561 ttggtttgat cttgctctac ttgacctatg cgattccaca gaccctcttt ctctatgttg
     7621 gctatatcaa aatctcgatt ccagaaagtc tggatgaagc agcagagatc gatggggcta
     7681 atcaatttac aacctatttc cgcatcatct tcccaatgat gaaaccgatg catgcgacaa
     7741 ccatgatcat caatgccctt tggttctgga atgacttcat gttgccactc cttgtcttga
     7801 accgggattc caaaatgtgg actctgcctt tgttccaata caactacgca ggccaatatt
     7861 tcaacgacta cggaccaagc tttgcctctt acgtggtcgg cattatcagt atcaccattg
     7921 tctatctctt cttccaacgc catatcattt caggaatgag caacggggca gtgaagtaat
     7981 actcaatgaa aatcaaagag caaactagga agctagccgc aggttgctca aaacactgtt
     8041 ttgaggttgt ggatgaaact gacgaagtca gtaaccatac ctacggcaag gtgaagctga
     8101 cgtggtttga agagattttc gaagagtata agaagagctc atggaatcta tagtctttga
     8161 cacagaggaa gagtttagct tgttgataat tctatgcaga aaacaagaaa gtagtacttt
     8221 gtttatcaca gtctatatta gtacgagttt gatgataaat agagatttaa aatgaatttt
     8281 atttatgaag ccagatcata tgagacttgg cttcaattag aaaaaggaga gtaatgatgc
     8341 caattcaaaa taaaaccatg ttgattacct attctgatag ccttggaaat aatcttaaag
     8401 acttatatga taatttggaa gagcattttg gagatgctat tggaggagtt caccttttac
     8461 catttttccc atcaacaggt gatcgtggat ttgcgccagt tgactacgac gaagtggact
     8521 cagcttttgg tgattgggag gatgttaagc atttaggtga gaaatattat cttatgtttg
     8581 attttatgat taatcatatt tctcgtcaat ccaagtatta taaggactat caagaaaaac
     8641 atgaagccag tgaatttaaa gctctctttt taaactggga taagttttgg ccagaaaacc
     8701 gtccgacaca gtctgatgta gatttaattt acaagcgtaa ggatcgtgca ccaaagcaag
     8761 agattgtgtt tgaagatggt tcagtggaac atttgtggaa tacctttggt gaggagcaga
     8821 ttgatcttga tgtgaccaaa gaagtaacta tggaatttat ccgtaagacc attcagcact
     8881 tggcaagtaa tgggtgtgat ttgattcgtc tagatgcctt tgcttatgca gtgaagaaat
     8941 tggatactaa tgatttcttt gtggaaccag atatttggga tttattggac aaagttcgag
     9001 atatcgctgc tgagtatggg acagagcttt tacctgagat tcatgaacac tattcgattc
     9061 agtttaaaat agcagaccat gattactatg tttatgattt tgctcttcca atggtgacac
     9121 tttatactct ttacagttcc agaacagagc gtttggctaa gtggttaaag atgagcccga
     9181 tgaagcaatt tacgacgcta gatacccatg atgggattgg agtagtagat gtcaaggata
     9241 tcctgaccga tgaggagatt gactatgctt caaatgaact ctataaggtt ggagccaatg
     9301 tcaaacgtaa gtactctagt gccgagtata acaacttaga tatctaccaa atcaattcaa
     9361 cctactattc agcgcttgga gatgatgatg tcaagtattt tctcgctcgt ctaattcaag
     9421 cttttgcccc aggtattcct caggtttact atgtgggtct attagcaggc aagaatgact
     9481 tgaaattatt agaagaaact aaagaaggtc gaaatattaa tcgtcattac tatagcaacg
     9541 aggaaatagc aaaagaagtg caacgacctg ttgtgaaggc ccttctcaat ctattttctt
     9601 tccgtaaccg ttcagaagcc tttgatctag aagggactac tgagatagag acaccaacag
     9661 ctcacagcat tgtaatcaaa cgtcaaaata aagataagtc cgtaacagca gtagcagaaa
     9721 ttgatttgca aaatcagact tatcgggtaa ttgagaatgg agttgaagta acattttgaa
     9781 gccttgatat ggtggataaa atagggtttt tattttggaa aacgtttcct ttgttttcaa
     9841 attgctaaaa aagtggtaca atataggaca gcttactatt atctgaatca gctgatttgg
     9901 agagaaagga ttcattttga aatcaatagg ctttattgaa aagctgaagg ggttgtctag
     9961 taaagagctg attttattgg gaattatcct aagtatcttt ttaccctttt atctttttgt
    10021 agttgtactc tgtttatata ttatcagttt gatttttaca ggagacatga aaagtattct
    10081 tcagaaaatg ggggagcatc cgatgctgct tctttttctt agctatagta ctgttatatc
    10141 cattcttgca caaaattgga tgggtcttgt ggcttcagta ggaatgtttc tatttactat
    10201 tttctttttg cactatcagt cgattttatc ccataaattc tttcgattga ttttgcagtt
    10261 cgtcttgttt ggtagtgtct tgtcagctgc ttttgccagt ttagaacatt tccaaattgt
    10321 gaagaaattt aactatgctt ttctttcacc caatatgcag gtgtggcatc agaaccgggc
    10381 agaagtgacc ttctttaatc ctaattatta tggaattatt tgttgtttct gtattatgat
    10441 tgctttctat ctgtttacaa cgaccaagtt gaattggttg aaagtattct gtgtgattgc
    10501 aggctttgtt aatctctttg gtttgaactt tactcaaaat cgaactgcct ttcctgctat
    10561 tatcgctgga gcaattatct atctctttac gactattaaa aactggaagg ccttttggct
    10621 tagtattggg gtcttcgcga ttggtttgag tttcctcttt tctagtgatt tgggagttcg
    10681 aatgggtact ttagactctt ctatggaaga acgcatttct atctgggatg ctgggatggc
    10741 cttgtttaag caaaatcctt tttggggtga agggccattg acctatatgc actcttatcc
    10801 tcggatacat gctccttatc atgaacatgc ccacagtctt tatattgata cgattctgag
    10861 ttacggaatt gtgggtacca ttttattagt tttgtcttct gttgctcctg ttcgcttgat
    10921 gatggatatg agtcaggagt cggggaaacg tccgattatc ggcctttatc tatctttcct
    10981 tacagtggtt gctgtgcacg gaatttttga cttggctctc ttctggattc agtcaggctt
    11041 tattttcttg ctagttatgt gcagtattcc attggagcat cgaatgttgg tatcggacat
    11101 gacggattaa gttttataag tttgaaatct tctaccttgg gtaggagatt tttttatacg
    11161 atgggcatgt cgtgcatctg aggtgtaagt cctctgtagg gatccactac cggtgaatac
    11221 aatagcgctc cccaagcctg actatcgtga ggtagcggat taaaatggtc tggggataga
    11281 tcgttttaag tctgacgcag gaaataagaa ttgtcagaga aagcaatagt gaaatcgtag
    11341 gctatgaata gaaacgtgat agcgaggagc atatagtgga taaggtagcg agaaatttta
    11401 aagtataaaa gatagtctta atctatatat gtaaatcaca aaagtaattg aattcggaat
    11461 aaggttggtg tgaaaagaca tagtaaactg aatcttgaat actagaatga tacttctaca
    11521 atattgttat aatttaattt gaattccaaa atcacattgt ttcgtccgta tttcatttta
    11581 ctgtatgtct tcctaaactc caaagtttct gcgtcaaatt tcctattttc actgtagtct
    11641 ttgacacttc gaacgacaat ttgaatcata tattcaaaaa aaaatgaaaa atttgtgcca
    11701 acaagcctaa atattctgaa aatttgtttg atttttaatg gataatgtga tataatggtt
    11761 gtcaatctat aattcacata aacagaggag tagaaaatga aaaaaaatcg tgtatttgct
    11821 acagcaggtc ttgttttatt agcagcaggt gtacttgcag catgcagttc ttcaaaatca
    11881 tctgattcat cagcccctaa agcttatggc tatgtttata cagcagaccc agaaaccttg
    11941 gactacctga tttcaagtaa aaatagtaca acagtagtga cttcaaatgg gattgatggt
    12001 ttattcacta acgataatta cggtaatctt gctcctgcag ttgcagagga ttgggaagtc
    12061 tctaaggatg gtttgaccta cacttataag attcgtaaag gggttaaatg gtttacctct
    12121 gatggagaag aatatgcaga ggtgacggct aaagatttcg tgaacggttt aaaacacgca
    12181 gcagataaaa aatcagaagc tatgtattta gctgaaaatt cggttaaagg cttggcagat
    12241 tatctatcag gaacttcaac agatttttca acagttggtg tcaaggcggt tgatgattat
    12301 acgttacaat acactttgaa ccagcctgaa ccgttctgga actctaagtt gacctattct
    12361 attttctggc ctctgaatga agaattcgaa acatcaaaag gaagcgattt tgctaaacca
    12421 acagatccga catccttgct ttataatggt ccattcttgt tgaaagggtt gactgcaaaa
    12481 tcttctgtag agtttgtaaa aaatgagcaa tattgggata aagaaaatgt ccacctagat
    12541 actatcaatc tagcttacta tgatggatca gatcaggagt cgctagagcg taacttcact
    12601 agtggagctt atagttatgc ccgtctttac cctaccagct ccaactattc taaggttgca
    12661 gaagaataca aggacaatat ctattacaca caatcaggct ctgggattgc tggtctgggt
    12721 gtgaatattg atcgccaaag ttacaactat acttctaaaa ctacagattc agagaaagta
    12781 gctactaaga aggcattgct taacaaagat ttccgtcaag ccttgaattt tgctcttgat
    12841 cgctcagctt actcagctca aatcaatggt aaagatggag cagctttagc agttcgtaat
    12901 ttatttgtaa aaccagactt tgtttcagct ggtgagaaga cctttggtga tttagtcgct
    12961 gctcaacttc ctgcttatgg tgatgagtgg aaaggtgtga atttagctga tgggcaggat
    13021 ggtttattca atgctgacaa ggccaaggca gagtttgcga aagctaagaa agctttagaa
    13081 gcagacggcg ttcagtttcc tattcatctg gacgttccag tagaccaagc atcaaaaaac
    13141 tacatatctc gtattcagtc ctttaaacaa tctgtagaaa cagttcttgg tgttgaaaat
    13201 gtcgttgttg atattcaaca aatgacaagt gatgaattcc ttaatattac ttactatgct
    13261 gccaatgctt catctgagga ttgggatgta tcaggaggag tttcatgggg gccagactat
    13321 caagacccat ctacttacct ggatatttta aaaacaacta gcagtgaaac tacaaaaaca
    13381 tatttaggat ttgataatcc aaatagccct tcagtagttc aagttggttt gaaagaatac
    13441 gataaattag ttgatgaagc tgccagagag acaagcgact tgaatgtccg ttatgaaaaa
    13501 tatgcagcgg ctcaagcatg gttgacagat agttcactct ttattcctgc tatggcttct
    13561 tctggtgcag caccagtgct ttcacgaatt gttccattta ctggagcttc tgcgcaaaca
    13621 ggctctaagg ggtcagatgt ttacttcaaa tatttgaaat tacaagataa agtggtgact
    13681 aaggaagagt atgaaaaagc tcgtgaaaaa tggttgaaag aaaaagctga atcaaatgag
    13741 aaagctcaaa aagaattggc aagtcatgtg aagtaaataa tttctaatag aactttctct
    13801 ccatgaggag aaggttcttt tgggattttt aaaggaaata atatgaaaaa atatattttt
    13861 atgcgtgttt tgcggtcatt ggtttcgatt ttcttagtaa cgactttgac ctacacgatt
    13921 atctatacct tggttcctcg aaaattgatt ttcaagcagg atcctaacta taataaaatt
    13981 gcgacaacgg ctgataaacg tgataactat gaaaatactg tgtttgagcg tatgggctac
    14041 attgagtatt acgatactaa agagttgcaa gaaaaggcaa gtagcatgga ttcttctgta
    14101 acagtagaag caaatgcgac caataaagct atttatgaaa agtacatcaa tcaattaggt
    14161 catggttgga ctttgggaga atttactgaa agtggtcaat tctatgctac tcgtgaaatt
    14221 ccaatttttg aacgtgtttt tcacttctat gctaacttga ttgacattga ccatacaaat
    14281 aaaatccaag accctgaaaa tccagacttg aaacgctacc ttcgttttga aaatgatcca
    14341 gctatcggat ggtcattggt cggttcagga actaaacata aatatctctt gtactttaac
    14401 agtcagttcc catttgttca tcaaaacttt gtgaacttga atttaggtga ctcttaccca
    14461 acctatgcta atacaccagt tcttcaggtt attactcaag gtcaaggaca aaccaaaact
    14521 gcccaagttc agttcccaac aggtaagaaa acgtcttctg taaatattta ctcaagaacc
    14581 tacaagtcac ctagtcaggc tgactctcgt gaagtagcta gctatgggaa agatgatcct
    14641 tatacagcga ctgaaagtaa ttaccaatat ccatctatga ttgtcagctc tgctattact
    14701 ggtttgattg gtttggttct tgcctatgct cttgccgtgc cacttggttc agccatggct
    14761 cgtttcaaga acacttggat tgatagcctc tcaacagggg ctttgacctt cttgcttgct
    14821 cttccaacga ttgccttggt ttacatcgtt cgattgattg gatcatctat tgcccttcca
    14881 gattcattcc ctatcttggg agctggagat tggcgttctt acgttttacc agcagtcatc
    14941 cttggtttgt tgggtgctcc tggtacagcc atttggattc gtcgttacat gattgacttg
    15001 caatctcaag actttgttcg tttcgctcgt gcaaaaggtt tgtctgaaaa agaaatttca
    15061 aacaaacaca tctttaaaaa tgccatggtt ccgctggttt caggaattcc tggtgccatt
    15121 attggggtta tcggtggtgc aacccttact gaaacagtct tcgccttccc aggtatgggt
    15181 aaaatgttga ttgactctgt aaaagcatct aataactcta tggtcgttgg tcttgtcttc
    15241 atctttacat gtatttctat cttctcacgt cttttgggag atatttggat gactattatt
    15301 gacccacgta ttaaattgac tgagaaagga ggcaaataat gtctacaatc gataaagaaa
    15361 aatttcagtt tgtaaaacgt gacgattttg cctctgaaac tattgatgcg ccagcatatt
    15421 cttactggaa atcagtgttt aaacaattta tgaagaaaaa atcaactgta gtcatgttgg
    15481 gaatcttggt agccatcatt ttgataagtt tcatctaccc aatgttttct aagtttgatt
    15541 tcaatgatgt cagcaaggta aacgacttta gtgttcgtta tatcaagcca aatgcggagc
    15601 attggttcgg tactgacagt aacggtaaat cgctctttga cggtgtctgg ttcggagctc
    15661 gtaactccat cctcatttct gtgattgcga cagtgattaa cttggttatc ggtgtttttg
    15721 tcggtggtat ttggggtatt tcaaaatcag ttgaccgtgt catgatggaa gtttacaacg
    15781 tcatctcaaa catcccacct cttttgattg ttattgtctt gacttactca atcggagctg
    15841 gattctggaa tctgattttt gccatgagcg taacaacatg gattggtatt gccttcatga
    15901 tccgtgtgca aatcttgcgc tatcgtgact tggaatacaa cttggcgtca cgtactttgg
    15961 gaacaccaac cttgaagatt gttgccaaaa atatcatgcc tcaattggta tctgttattg
    16021 tgacaaccat gactcaaatg cttccaagct ttatctcata cgaagccttc ttgtctttct
    16081 tcggtcttgg attaccgatt acagtgccaa gtttgggtcg tttgatttcg gattattcac
    16141 aaaacgtaac aaccaatgct tacttgttct ggattccatt gacaaccctt gtcttggtat
    16201 ccttgtccct tttcgtagtt ggtcaaaact tagcggatgc tagtgatcca cgtacacata
    16261 gataggagta gaaatgacaa aagaaaaaaa tgtaattttg actgctcgcg atattgtcgt
    16321 ggaatttgac gttcgtgaca aagtattgac agccattcgc ggcgtttccc ttgaactagt
    16381 cgaaggagaa gtattagcct tggtaggtga gtcaggatca ggtaaatctg ttttgacaaa
    16441 gaccttcaca ggtatgctcg aagaaaatgg tcgcattgcc caaggtagta ttgactaccg
    16501 tggtcaggac ttgacagctt tatcttctca caaggattgg gaacaaattc gtggtgctaa
    16561 gattgcgact atcttccagg acccaatgac tagtttggac cccattaaaa caattggtag
    16621 tcagattaca gaagttattg taaaacacca aggaaaaaca gctaaagaag cgaaagaatt
    16681 ggccattgac tacatgaata aggttggcat tccagacgca gatagacgtt ttaatgaata
    16741 cccattccaa tattctggag gaatgcgtca acgtatcgtt attgcgattg cccttgcctg
    16801 ccgacctgat gtcttgatct gtgatgagcc aacaactgcc ttggatgtaa ctattcaagc
    16861 tcagattatt gatttgctaa aatctttaca aaacgagtat catttcacaa caatctttat
    16921 tacccacgac cttggtgtgg tggcaagtat tgcggataag gtagcggtta tgtatgcagg
    16981 agaaatcgtt gagtatggaa cggttgagga agtcttctat gaccctcgcc atccatatac
    17041 atggagtctc ttgtctagct tgcctcagct tgctgatgat aaaggggatc tttactcaat
    17101 cccaggaaca cctccgtcac tttatactga cctgaaaggg gatgcttttg ccttgcgttc
    17161 tgactacgca atgcagattg acttcgaaca aaaagctcct caattctcag tatcagagac
    17221 acattgggct aaaacttggc ttcttcatga ggatgctcca aaagtagaaa aaccagctgt
    17281 gattgcaaat ctccatgata agatccgtga aaaaatggga tttgcccatc tggctgacta
    17341 ggaggaagga aatgtctgaa aaattagtag aaatcaaaga tttagaaatt tccttcggtg
    17401 aaggaagtaa gaagtttgtc gcggttaaaa atgctaactt ctttatcaac aagggagaaa
    17461 ctttctcgct tgtaggtgag tccggtagtg ggaaaacaac tattggtcgt gctatcatcg
    17521 gtctaaatga tacaagtaat ggagatatca tttttgatgg tcaaaagatt aatggtaaga
    17581 aatcgcgtga acaagctgcg gaattgattc gtcgaatcca gatgattttc caagaccctg
    17641 ccgcaagttt gaatgaacgt gcgactgttg attatattat ttctgaaggt ctttacaatc
    17701 accgtttatt taaggatgaa gaagaacgta aagagaaagt tcaaagtatt atccgtgaag
    17761 taggtcttct tgctgagcac ttgactcgtt accctcatga attctcaggc ggtcaacgtc
    17821 aacgtatcgg tattgcccgt gccttggtca tgcaaccaga ctttgttatt gcagatgagc
    17881 caatttcagc cttggacgtt tctgtacgtg cccaagtctt gaacttgctc aaaaaattcc
    17941 aaaaagagct cggcttgacc tatctcttca tcgctcatga cttgtcggtt gttcgcttta
    18001 tttcagatcg tatcgcagtt atttacaagg gtgttattgt agaggttgca gaaacagaag
    18061 aattgtttaa caatccaatt cacccatata ctcaagcctt gctttcagca gtaccaatcc
    18121 cagatccaat cttggaacgt aagaaggtct tgaaggttta cgacccaagt caacacgact
    18181 atgagactga taagccatct atggtagaaa tccgtccagg tcactatgtt tgggcgaacc
    18241 aagccgaatt ggcacgttat caaaaaggac taaactaata atggttttat aatttccatg
    18301 tcaattttta tgggaattat aaaacttttt ttgttggact gatttgaaaa actttgaaag
    18361 cttcctgaaa gaattttcga aaaattttaa aaaattttga aatattattg acaggtgatg
    18421 aaaaaggtgg taggatagga aggatcaaaa aagaaagcag aaaaagaaat gaataagaga
    18481 caagccgtaa ctatgaatca aaacttttac tttagctact ttagatagtg tttgtagaca
    18541 tgtcaccatg gatgcaaaca gttcaagcaa tttgtttgta tctatgtggc taagattttt
    18601 gattgtggtc catatagatg aatatctaaa tggactagct aagttgtaac ttgttaggtt
    18661 atttcaagta cccgtttaga tagtatctag gcggtttttt gttttatctt ttctgagaag
    18721 gagtttcatt atgaaagttg ttcgaaaatc actagccccc tcttggtagt ggggatcctc
    18781 ttgacttctc tgatcagttt gcatcagttg aaggcagata agaaaagaga tgtctttcgt
    18841 atcggtattt cgcagtttat tacccaccag tccttagacg ctactagaga aggatttgtg
    18901 gatgagctgg ccaaacaagg ctatgttgag ggggaaaata ttgagattga tttgcaaaat
    18961 gcacagggag aacaaagaaa tctaaaaacg atttcccagc aactagcaga atccagcgat
    19021 gtcgttctag ccatcgcaag gccttctgct cagagcttgg ccaatacgac gcaaacgcca
    19081 ccagttatct tttcagctgt aacagaccca gtcagtgcca agttggttga gtcaagagaa
    19141 catcctgggg gcaatgtaac tgggacaagc gatcagtcat cagatgccat ttcaacccaa
    19201 atcaatttga taaagaaagt gttgccaaag gctaaaacga ttggaatcct ctatactcag
    19261 agcgagccca attcggttgt ttaaaatgat gaagctaagc gacttctgaa agaaaaaggc
    19321 tttaccgttg ttgaaaaaac aatcttggac agtaataacg tcaaggcggc agcagagagt
    19381 ttgatggcag aggtggatat ggtttttgtc ccaactgata atatcatttc gtcaaccatg
    19441 gaaacagtta agcaggtttc tattaaacac aaggttccag tattcggtgg ttcaacagaa
    19501 atgattgctg ttggtgactt gtataactac ggaaccaatt atgaagaatt gggaagacag
    19561 acagctcgca tgctgattcg tgttttaaaa ggtgagaaac cagaaaatat agcagttgag
    19621 ttgcctgaaa aactggaatt gcataccaat caagaaatgg cagatgcatt gggaattgat
    19681 attagtaagt tagaaggcaa ggaataagga ggattaagat gaattttgtg ttatctagtt
    19741 tatcagaagg tttgttgtgg tcgattgtgg cgattggggt ctacttgact ttccgtattt
    19801 tggatattgc ggatataact gctgagggag cctttcctct gggggcagca gtcgttgtat
    19861 cacagataca ggcaggggca aatccttggc ttgcgacttt acttgctttg ctggcaggta
    19921 tggtagcagg tcttgtatca ggaatgctcc acaccaagat gaaaatccca gctctcttga
    19981 cagggattgt gaccttgaca gggctctatt caatcaatat taaaattatg ggcagtgtac
    20041 ccaatctttc cttgggagat tctgcaaccg tctttaaaca gttggcgagc ttgggtctga
    20101 caaatgaagg agctgttttc tcacttagtt tagtctgtct cttacttgtt tggtcttgac
    20161 ccttttgatg aaaacagaga ttggtttggt cttgcgttcg actggggata atatcccgat
    20221 aagtgaggcc aatggagtca atgtagacac catgaagatt gttggttaca tgatttcaaa
    20281 cggtttgatt gccctatgtg gttccttgtt tgcccaaaat gatggatttt cagatgtgac
    20341 ttctgggaca ggaaccattg ttgttggttt gagctcggaa gtcttgatac acgacttgac
    20401 cattggaggc cgcttattat ccatcggaat cggtgctatt gtttaccgtt tgattatttt
    20461 aaatatctat gaaattccaa atctagatca aaacttggta cgtctcttta atgcaatctt
    20521 gctcgctttg gttttatttg caccagaatt gcaaaagaga ttaaagattc gtggtctgaa
    20581 attgagaaat gaataggagg agaaagttat ggcaagtttg ttaacacttg aaaatattca
    20641 caagacattt gaagcaggga cggtcaatga gaaccatgtc ctcaaaggat tagatttaga
    20701 ggttgaagag ggagatttta tctatgtgat tggtggaaat ggagcaggaa aatccacttt
    20761 gatgaatatc ttggctggca atctatcggt ggacgaaggg gaccttctac tggcagggaa
    20821 atccattaaa aatctgagtg tcagaaagag agccaaggat attgcccgtg tttttcaata
    20881 tcctaagatg ggaacagctt ctcgtttgac gattgaggag aatatggcta ttgccttgag
    20941 acgtgggcaa aagagagggc ttggttgggg tgtgaaggag aaggatagaa tccagttcca
    21001 agaggccttg aaggagttga atattggtct tgaaaaccgc ttaaaagtag atactcaata
    21061 tctctcagga ggacaaagac aggctttgac cctagtcatg gcagctctgg tgaaacccaa
    21121 acttttactt ttggatgaac atactgcggc acttgacccg aaaaccagtc aaatggtgat
    21181 ggacttgacg caaaagattg tggagcacca tcagtggacg actttgatga ttacccatga
    21241 tatgaatcat gcgattgagt acggcaatcg tctcattatg ctctatcaag gcaagatagt
    21301 ggtggatgtc aagggagaag agaaaaagca tctgacagtt gaagacctta tgcatctctt
    21361 ccagaaaaat agtggccaaa gtctggtcag tgatgaatta gttttgggat aaagaaaaag
    21421 gctgagatct ggtgtctcag tcttttattt cttgcgtttt gcaaaatcta caaatctaaa
    21481 tttttctaac ttatggcgac tttcggtaaa ctgaaattgg cgtccgtctt ggagatagac
    21541 ttttgattta atcgaaacga cataagggtc tttgccaatg tccatgagaa tcttgtctcg
    21601 gtcgcttgag tggtcaatgg tgatttcctt ctgagcataa tcaataagga gtttgaggcc
    21661 attttctata taagaataga tagactgctc agcaatttgg cgagtgagat ttggaattag
    21721 ttccatatcc agatagtctg tatccagaac ggataccaga tcatccacca cacgctggcg
    21781 gaccaccttc caaaccatcc gaaactctgg gaaaccggtt atcagtgagg attttttatc
    21841 aataataatc ttgtccagac tgaccacgtt ggttttagag cgcagtccaa gttctttaac
    21901 tagttcttgg tagctggtta ggttggatac agggaaattg acggtttctt ctttgacgac
    21961 ttgagaacct tgccctctta tctttttgat caatccttcc tcttggagga gagacagggc
    22021 ctttcggacg gtatcacgac tcacttgata ttgctccata aggtcgtgct cgctaggaag
    22081 gaaatctccg acagcgtaag tctcgttttg aatggtttct tggatttgct taaataattg
    22141 ttggtatttc ttcattttgc ctgcttaaat aggtttttag tctagtttaa tgaacacctg
    22201 tatctatttt accatacaag tgctagaaaa tttacaaaaa aacacccttt ttataccaaa
    22261 caagttgcag acaagtttgg tatcgtttac aatatactta tcaaatcaaa cttgctttga
    22321 caagtataag gagaatcaaa tgggaaaatt tgaacaagaa gccaaagatc tgcttcaggc
    22381 aattggaggc aaagaaaatg tgactgccgt aactcactgt gcgacacgga tgcgctttgt
    22441 tttaggagat gataagaagg ctaatgttaa agctatcgag tcaattccag ctgttaaagg
    22501 aacttttaca aatgcaggtc aatttcaggt aatcattgga aatgacgtgc ccatctttta
    22561 taatgatttt acagccgttt caggtattga gggtgtttcc aaagaagcag ccaagtctgc
    22621 agctaagagt aatcaaaacg tggtccaacg tgttatgacc actctggcgg agatttttac
    22681 tccgattatt ccagccttga tagtcggagg attgatcctc ggtttccgta atgtcttgga
    22741 aggtgtccat tggtcgatgt tggatggcaa gaccatcaca gaatcctctc agttttgggc
    22801 aggtgtcaat cacttcctct ggttgcctgg tgaagctatc ttccagttct taccagtagg
    22861 gattacttgg tctgtttctc gtaagatggg aaccagccaa attttgggaa ttgttctcgg
    22921 aatctgtttg gtatcgcctc agttgctcaa tgcctatgcg gttgcttcaa cgccagcagc
    22981 tgatatcgcg gcaaactggg tttggaattt tggctatttt actgttaatc gtatcggtta
    23041 ccaagcccaa gttatcccag ccttgcttgc aggtttgagt ctgtcttatc ttgaaatctt
    23101 ctggcgcaag catatcccag aagtcatttc tatgattttt gtacctttct tgtcattgat
    23161 tccagccttg attttggctc atactgtttt gggaccaatc ggttggacaa ttggacaagg
    23221 gctttcatca gttgtcttgg caggtttaac tggtccagtt aaatggctct tcggtgcaat
    23281 ttttggtgcc ctctacgctc catttgtcat cacaggtctg caccatatga ccaatgccat
    23341 tgatacacaa ttgattgcgg atgctggtgg cactgcccta tggccaatga ttgctctttc
    23401 taatattgct caaggctcag ccgtgtttgc ctattatttc atgcatcgcc atgatgagcg
    23461 tgaggctcag gtttcacttc ctgcaaccat ttcagcctat ctcggtgtta cagaaccagc
    23521 tctttttggg gttaacgtaa aatatattta tccatttgtt gctgggatga ctggttcagc
    23581 ccttgcaggc atgttatccg ttacttttaa tgtaactgcg gcttctattg gtatcggtgg
    23641 tttgccaggt attctctcta ttcaacctca atacatgctg ccatttgcag gaactatgct
    23701 agttgcgatt gttgttccaa tgctcttgac tttcttcttc cgcaaggctg gtctctttac
    23761 aaaaacagag ggcgatacga acttgcaggc agaattcgtt gctcaagaag aagcagaatt
    23821 tgtgaaccat gaaccagtag aacttacttc ggtagaaatt atcagcccac taactggcca
    23881 agtgaaagaa ttgagtcaag cgacggatcc tatttttgca tcaggtgtca tggggcaagg
    23941 tctagtcatt gaaccaagcc aaggtgagtt gacctctcca gttaatggga cagtgacggt
    24001 tcttttccct accaagcatg ccatcggcat tgtctctgac gagggagttg aattgctcat
    24061 ccacatcggt atggatacag taggtcttga tggcaaaggt tttgaaagtc ttgtagtcca
    24121 aggagatcac gttacagttg gtcagcaact gattcgtttt gatatggatg tcattaaggc
    24181 tgcaggtctg gtgacagaaa ctcctgttat catcaccaac caagatgctt atacagcgac
    24241 tattcccgga acttatccga caacgatcca agctggagca tctctcatgg tcgctacacg
    24301 aatctaatac tcttcgaaaa tctcttcaaa ccacgtcagc tctatctgca acctcaaaat
    24361 agtgttttga gcaacctgtg gctagcttcc tagtttgttc tttgattttc attgagtata
    24421 attgaaatag cacaaatagg gacggaagac tgcttcctcc cttttatcag aaaaggagaa
    24481 acagatgaca cttgataaag gaaaagtagt ctatcaaatc tatccaaaat cttacaaaga
    24541 caccactgaa aacggtattg gggatttccg tgggattatc ggaaaaattc cctatctagc
    24601 caaactaggt gtggatatgg tctggctcaa tccattctat ccaagtcctc aacgggataa
    24661 tggttacgat atttcagatt atatggcagt ggatcctctt tttggtgata tggctgattt
    24721 tgaggaaatg gtgtgtatcg gtaaagagca caagattgac tttatgctgg acatggtact
    24781 taatcattgt tcgacagagc atgaatggtt tcagaaagcc ctagctggtg ataagtatta
    24841 tcaagacttt ttcttcatcc aagaccaacc aacagattgg cagtctaagt ttggtggttc
    24901 tgcatgggcg cctttcgggg atactgggaa atactatctt cacctatttg atgagaccca
    24961 ggctgacctt aactggcgca atcccaatgt ccgtaaggag cttttcaagg ttgttaattt
    25021 ctggcgcgac aagggtgtca aaggttttcg atttgatgtg atcaatttga ttggtaagga
    25081 cgaggtttca gtggactgtc ctgaaaatga agggaagcca gcttatacag acaaacccat
    25141 cgttcataac tatttgcgta tgatgaacca agccactttt ggatctgacg atagctttat
    25201 gacagttggg gaaatgtctt ctaccaccat ggaaaactgt gtcctctatt cgtcgcctga
    25261 tcgtcaggaa ttatccatga cctttaattt tcatcacctc aaggtggact ataaggatgg
    25321 acaaaagtgg accttggctc cctttgattt tgaagagttg aagagtcttt accatagttg
    25381 gggtaaggaa atgagtgata aagacggttg gagtgccctc ttttggaaca atcacgatca
    25441 accacgtgcc ttgaaccgtt ttgtcgatat tcaaaacttc cgcaaggaag gagccaccat
    25501 gctagcagcc agcattcacc tgtcacgtgg gacaccttat atctacatgg gtgaggaaat
    25561 cgggatgatt gacccagact attattctat ggctgattat gtggatgtcg aatcgcttaa
    25621 tgcctatcag atgctcttag aagaaggaaa gagtcagcaa gaagccttcc agattattca
    25681 agctaagtcg cgtgataatt cacgcattcc catgcagtgg gatgcttcgg aaaatgcagg
    25741 attttcaaca ggcactcctt ggttgaaagc tggtaaatcc tataaataca tcaatgtaga
    25801 aaatgaaatc cagggtccga tttttacctt ctatcaagac ttgattcgac tgcgtaagga
    25861 aatgccaatc atttcagaag gaagttacaa accagccttt gaagatagca aacaagtcta
    25921 cgcttttgaa cgccagtttg aggatcaaaa gttactagtg ctcaataact tttatgctaa
    25981 agaagtggaa atcgacttgc cagcagtcta ccaaaatgga cagattttga tttcaaacta
    26041 tgaagatgca gaagtgtctg agaaaattct actaaaaccc tatcaaacac tggctattta
    26101 tgtaaattaa acttagcaag gagacctctt tttcagaaaa gcagggttct ttttgctgtc
    26161 tattccatcc ttgaaagtgt agaacaaact ggtcagggtg gctagtttgt ggtataatga
    26221 aagggactca aaaagaaaca ggagaaaaat gatggattta cttttagcaa ttgtattgat
    26281 tgtgctagct tttctaggag gagctcttgg aggaatgtac ttggttcgta agcaaatcga
    26341 aaaagaattt gctgacaacc cacgtttgaa tgctgaagca gttcgtactc ttttgagtgc
    26401 aaatggtcaa aaaccaagcg aagctaaggt acaacaagtt taccaccaaa tcatccgcca
    26461 acaaaaggca gcccttgcta acaataaaaa gaaaaaataa ataaggaaaa gtctgggatg
    26521 aaagttccag acttctcact atgttggtta tggtttaggg atgagacttt ttccttgcat
    26581 tctattgata tttgattatg attaagagag aggtagttga cattctatca agctgtcggt
    26641 cagttcgttc agtacaagga atcataatga acgatcaatc agaaaaaaga ctagaaagaa
    26701 gactgtatgg ataatcgacc aattggtttt ttggattcgg gtgtcggggg cttgaccgtt
    26761 gtgcgcgagc tcatgcgcca gcttccccat gaagaaatcg tctatattgg agattcggcg
    26821 cgggcgccct atggcccccg tcctgctgag caaattcgtg aatatacttg gcagctggtc
    26881 aactttctct tgaccaagga tgtcaaaatg attgtcattg cttgtaacac tgcgactgcg
    26941 gtcgtctggg aagaaatcaa ggctcaacta gatattcctg tcttgggtgt aattttgcca
    27001 ggagcttcgg cagccatcaa gtccagtcaa ggtgggaaaa tcggagtgat tggaacgccc
    27061 atgacggtac aatcagacat ataccgtcag aaaatccatg atctggatcc cgacttacag
    27121 gtggagagct tggcctgtcc caagtttgct cccttggttg agtcaggtgc cctgtcaacc
    27181 agtgttacca agaaggtggt ctatgaaacc ctgcgtccct tggttggaaa ggtggatagc
    27241 ctgattttgg gctgtactca ttatccactc cttcgcccta ttatccaaaa tgtgatgggg
    27301 ccaaaggttc agctcatcga tagtggggca gagtgcgtac gggatatctc agtcttactc
    27361 aattattttg aaatcaatcg tggtcgcgat gctggaccac tccatcaccg tttttacaca
    27421 acagccagta gccaaagttt tgcacaaatt ggtgaagaat ggctggaaaa agagattcat
    27481 gtggagcatg tagaattatg acaaataaaa tttatgaata taaggatgac caggactggt
    27541 atgttgggtc ttatagtatt tttggtggcg ttaacagttt gagcgactat cagacagatt
    27601 ttcctctgtt tgaattctcc aaaatatttg gagatgaaga gtatggtttc ccgctttcag
    27661 ttactgtttt acgctatggt tctacctacc gtttgttctc ctttgtggta gatatgctta
    27721 atcaagaaat gggacgaaac ttggaagtta ttcaacgtca tggggccctg ctcttggttg
    27781 aaaatgggca actcttgtat gtagaattgc ctaaagaagg ggtcaatgtt catgatttct
    27841 ttgagacaag caaggtcaga gaaaccttgt tgattgcgac tcgtaacgaa ggcaaaacca
    27901 aggaattccg agctatcttt gataagttag gctacgatgt ggaaaatctt aatgactacc
    27961 ctgacctgcc tgaagtagca gaaacaggta tgacctttga agaaaatgcc cgccttaagg
    28021 cagaaaccat ttctcaatta acgggtaaga tggttttggc agatgattct ggtctcaaag
    28081 tcgatgtcct tggtggctta ccaggcgtct ggtcagctcg tttcgcaggt gtgggagcaa
    28141 ctgaccgtga aaataatgcc aaactcttgc acgaattggc catggtcttt gaactcaagg
    28201 accgctcggc tcagttccac acaaccctag tcgtagccag cccaaataag gaaagtttag
    28261 ttgttgaagc agactggtca ggttatatta actttgaacc taagggtgaa aatggctttg
    28321 gctatgatcc cctcttcctt gtaggagaga caggtgagtc atcagctgaa ttaaccctgg
    28381 aagaaaaaaa tagtcaatct caccgtgcct tagccgttaa gaaacttttg gaggtatttc
    28441 catcatggca aagcaaacca tcattgtaat gagcgattcc catggcgata gcttgattgt
    28501 ggaagaagtc cgtgatcgct atgtgggcaa agtcgatgcc gtttttcata acggcgattc
    28561 tgaactacgt ccggattctc cactttggga gggcatccgc gttgttaaag ggaacatgga
    28621 cttctacgcc ggctacccag aacgtctggt gactgagctt ggttcgacca agattatcca
    28681 aactcatggt cacttgtttg acatcaattt caactttcaa aagttggact actgggctca
    28741 ggaggaagag gccgctatct gcctctatgg tcacttgcat gtgccaagtg cttggatgga
    28801 aggcaagatc ctctttctaa atccaggttc tatcagccaa ccacgaggta ccatcagaga
    28861 atgtctctat gctcgtgtgg agattgatga tagttacttc aaagtggact ttttgacacg
    28921 agatcacgag gtgtatccag gtttgtccaa ggagtttagc cgatgattgc caaggagttt
    28981 gagactttct tgttggggca ggaggaaact tttttgaccc ctgctaaaaa tctagctgtg
    29041 ttgattgata cccacaatgc ggatcatgcg accctcttgc ttagtcagat gacctatacc
    29101 cgtgttcccg ttgtgacaga tgaaaaacag tttgttggga cgattggact cagagatatt
    29161 atggcttatc agatggagca tgacttgagc caagaaatca tggcggatac ggatatcgtt
    29221 catatgacaa aaacggacgt agcggttgtt tcgcctgatt tcaccattac ggaggtcttg
    29281 cacaagctag tagatgagtc cttcttaccg gttgtggata cagagggtat tttccaaggg
    29341 attattacgc gcaagtccat cctcaaggcc gttaatgccc tcttgcatga ttttagtaag
    29401 gaatatgaga ttcgatgcca atgagagaca gaatttcagc ctttttagag gaaaagcagg
    29461 gcttgtctgt caattccaag cagtcctata agtatgattt ggagcaattt ttagacatgg
    29521 taggtgagcg gatttctgag accagtctca agatttacca agcccagcta gccaatctaa
    29581 aaatcagcgc ccagaagcga aagatttcgg cctgtaacca atttctatac tttctctatc
    29641 aaaaaggaga ggtggacagc ttttaccgct tggaattagc caaacaagct gaaaagaaga
    29701 cggaaaagcc agagattcta tacctagact ctttttggca ggaaagcgac catccagagg
    29761 gccgcttgct agcgctctta atcctagaaa tggggctctt gcccagtgag attttagcca
    29821 tcaaggttgc ggacatcaat ctggattttc aggtgctgcg aatcagcaag gcttcccaac
    29881 agaggattgt caccattccc acggccttgc tttcagaatt ggaacccttg atggggcaga
    29941 cctatctttt tgaaagagga gggaaaccct attctcgtca gtgggccttt cgtcagttag
    30001 aatcttttgt caaggagaaa ggttttccat ccttatcagc tcaagtctta cgtgaacagt
    30061 ttattctaag acaaatagaa aacaaggtcg atttgtacga aattgcaaaa aaattaggat
    30121 taaaaacagt cctgacctta gaaaaatata gataatggat attaaattaa aagattttga
    30181 aggacccctg gacttactct tgcatctggt ttctaagtac cagatggata tctacgatgt
    30241 gcccattacg gaagtcatcg aacagtatct agcctatgtc tcaaccctgc aggccatgcg
    30301 tctggaagtg acgggtgagt acatggtcat ggctagtcag ctcatgctga ttaagagtcg
    30361 taaactcctt ccgaaggtag cagaagtgac agacttgggg gatgacctgg agcaggacct
    30421 cctctctcaa atcgaagaat atcgcaagtt caagctcttg ggtgagcact tggaagccaa
    30481 gcaccaagaa cgggcccagt attattccaa agcgccgaca gagttgattt acgaagatgc
    30541 ggagcttgtg catgacaaga cgaccattga cctctttttg gctttttcaa atatcctagc
    30601 caagaaaaaa gaggagtttg cacaaaatca cacgacgatc ttgcgggatg agtataagat
    30661 tgaggacatg atgattatcg tgaaagagtc cttgattgga cgagatcaat tgcgcttgca
    30721 ggatttgttc aaggaagccc agaatgtcca agaggtcatc accctctttt tggcaaccct
    30781 agagttaatc aaaacccagg agctgatcct cgtgcaagag gagagttttg gagatatcta
    30841 tctcatggaa aagaaggaag aaagtcaagt gcctcaaagc tagacttgat agagaggaaa
    30901 gatgagtact ttagcaaaaa tagaagcgct cttgtttgta gcgggtgaag atgggattcg
    30961 ggtccgccag ttagctgaac tcctctctct accaccgaca ggcatccagc aaagtttagg
    31021 aaaattagcc cagaagtatg aaaaggaccc agattccagt ttggctttga ttgagacaag
    31081 tggtgcttat agattggtga ccaagcctca atttgcagag attttgaagg aatactctaa
    31141 ggcgcctatc aaccagagct tgtctcgggc tgcccttgag accttgtcca ttattgccta
    31201 caaacagccg attacgcgga tagaaattga tgccatccgt ggagttaact cgagtggagc
    31261 cttggcaaag ttgcaggctt ttgacctgat aaaggaagac gggaaaaagg aagtattggg
    31321 gcgccccaac ctctatgtga ctacggatta tttcctagat tacatgggga taaaccattt
    31381 agaagaatta ccagtgattg atgagcttga gattcaagcc caagaaagcc aattatttgg
    31441 tgaaaggata gaagaagatg agaatcaata agtatattgc ccacgcaggt gtggccagta
    31501 ggagaaaagc agaagagctg attaagcaag gcttggtgac ggttaacggc caagtggtgc
    31561 gtgaactagc aaccactatc aagtcaggcg acaaggtcga agttgaaggt caacctatct
    31621 acaacgaaga aaaggtctac tatctgctta acaaaccacg cggtgtgatt tccagtgtga
    31681 cagatgataa gggtcgcaag acggttgtcg acctcttgcc caatgtcaaa gagcgtattt
    31741 accctgtggg tcgtttggac tgggatacat caggagtctt gattttgacc aatgatgggg
    31801 actttacaga cgagatgatt caccctcgta atgagattga caaggtttat gtcgcgcgtg
    31861 ttaaaggtgt ggccaataag gacaatctcc gccccttgac ccgtggtctt gagattgatg
    31921 gtaagaaaac caagccagct gtttatgaaa ttctcaaagt ggacccagtc aaaaatcgct
    31981 ctgtggtgca gttgatcatc catgaagggc gtaaccatca ggttaaaaag atgtttgaag
    32041 ctgttggtct ccaagtagat aagttgtctc ggactcgttt tggacaccta gacttgacag
    32101 gactccgtcc aggagaatcc cgtcgtctta ataaaaaaga aatcagccaa ctacacacca
    32161 tggctgtaac taagaaataa tgaaacgaat tttaatagcg cctgtgcgct tttaccaacg
    32221 ttttatctca ccagtctttc caccctcttg tcgctttgag ctgacttgtt ccaactacat
    32281 gattcaggct attgaaaaac atggttttaa gggggtattg atgggcttgt ctcggatttt
    32341 acgttgtcat ccctggtcga aaacaggtaa ggaccccgtt ccagaccgct tttcccttaa
    32401 acgaaatcaa gaaggggaat gaggtggggt aaatagattt caaaatgata aaaacgcatc
    32461 ctatcaggtt tgagtgaact tgataggatg cgttttagaa tgtcaaaatt ttatactctt
    32521 cgaaaatctc ttcaaaccgc gtcagctttc atctgcaacc tcaaaacagt gttttgagca
    32581 acctgcggct agttttctag tttgctcttt gattttcatt gagtattaaa ttgagtttga
    32641 agtggcttat ttcaaagctt tttgtatgtc ttcaatcatg agttttgttg attcaagtcc
    32701 gcctccgctt agataccaga ggtctggtgt tagttggata atcttaccat ttttagcagc
    32761 aggtgtttca gcgataaggg cattttctag gacaccgtcg ttgctagagt tgtccccacc
    32821 gatggcaagg gtacggttga tgacaaagag gatgtcaggg ttgatttctt tgacactttc
    32881 aaagctgact tcttgtccgt ggcgtgagtc ttcaaatgtt gtatcagttg gtttgaattt
    32941 caaggtttgg tacaagaaag agaaacgaga tttggcacca aaggctgcca tttttccttc
    33001 attaaggagg atcgcaaggg cttttttgtc agagctttca tttttagtag cgacttcttg
    33061 gatgctcttg tctagcttgg ccaattcttc cttggctttc tgtgtaccag tttcgccgaa
    33121 ggcacttgct aaggattcga tattagcctt ggtagaagtc cagtagtcgt ccttgcttgc
    33181 ttggaagaga acggttgggg cgatttcttt gaatttgtct acgaattttt gtgtacgtgg
    33241 tgaagcgata atcaaatcag gctcaagggc ggcgatagct tctaaatcag gttctttcat
    33301 agaaccaaca tttttgacag ttcccactag gtcttttaga taagtcggaa cagtttttgt
    33361 aggcattccg acgatatttt tttcaaatcc taaagcgcga atagtatccg cagcgccgag
    33421 gtcaaaggtc acaatctttt caggaacttt ggaaagtttg acctcgtcca gtgaactttt
    33481 aatggttacc tctgttggag cagagctact ggtctctgtc tgactagtgc ttgagtttgt
    33541 actacatgca ccaagtagga gcaagaagct ggccactagg gcagtgaaat aaagtttaag
    33601 ggatgttttc ataatttctc ctttttaaaa tgtgataacg atttagggag tctcttaatc
    33661 ttattgacta agagactgaa ggttctctaa cttgagcttt tatgttacta gctatagata
    33721 cagatctttt tgttattgat atcagctagc gtgatgggaa tctcataaag ttgactgagc
    33781 aggtcagcct gcatgatttg atcggttctt cccttgctaa agacctggcc gtccttgaag
    33841 gcgacaattt catctgcata ctgactggcc atgttgatat cgtggaggac gatgataatg
    33901 gtcttgccga gttcctccac cagtcgtcga agaatctgca tcatgctgac gctttgcttg
    33961 atatcgagat tgttgagtgg ttcgtccagc aagataaagt ccgtatcctg ggccagtacc
    34021 atagcgataa agacgcgctg gagttgcccc cctgacaggc tattgatgta gcggtctttt
    34081 aagttggtca gttccaaata gttcagagtt tctcggattt tttcccagtc ttctgatcta
    34141 agtcgacctc ggctgtaggg aaaacgtcca aaactgacca gttcttcaac agtcaatttg
    34201 gcttggtaat tgattttctg ttttaggatg gttagttctt gggccagttc ttgcgaattc
    34261 cagctctcga tttcacgtcc tttgatactg agaactccct gatctttctt ggttagtctg
    34321 ctcatgatgg agaggagagt cgattttcca gcaccatttg gaccaataaa ggctgtcagt
    34381 ttttgaggac tgacttcaag cgaaatgcct tgcaaaatat cctgtttttg aatggatttg
    34441 tcaatgtttt ccagtttcac tgacgagccc tcctatatag taagataaag aataagaagc
    34501 cacccacact ctcaatgatc atactgatac gaatttccag tgcaaagact cgttcaatca
    34561 aggcttgccc caaggttaag ctaataaatc caaccagaat ggccactata aagagtaact
    34621 tgtgctgata gtctttgaca atcaggtagg tgaggttggc cagcataaag ccgaagaagg
    34681 ccataggtcc taccaaggca gtggccgttg aggtcaaaag cacgattccc cagaggagct
    34741 ctttctgttc tttttcaaca tcgagtccca atatctgagc cgtttctctt tgcaggtgca
    34801 agacatctag aacgactgct tttcgaaaga aaaagattgt caaagcgagg atgatcagag
    34861 aaccgatggc taggatggaa gtgttaagat gttgaaagga ggcaaaaaga ctattttgca
    34921 gtttatcgta ttcgtttgga tccattagga cttgaaggaa ggtgctgata tttcgaaaga
    34981 gacttctgag cgctagacag atcagcagga tgaagaccag gtcttgcttc atcagtgtct
    35041 tcaagtaacc ttgtaaggcg agaaagaaga gggactggac aagaagtaag actaggaatt
    35101 ctaagatagg ggatttgccc agttgaagaa acttgctttc aaaaaccagt agtagggttt
    35161 gtagtaggac gtagaaggat tcaattccca aaatactagg cgtcaggaag cgattttccg
    35221 tcagggtttg aaaactaatg gtcgaaatcc cagtcgcgat ggctaccaag agataaacga
    35281 tgatcttttg ggaacgcaac ttccaagcaa aggctgacaa gtgagtgatg ggccaaaagt
    35341 agagaagaca agctccgatg gcaagaataa tgagaatcca gaagagcttg gtatgtttgc
    35401 ttttagtctg catcttttcg tccccctctc cagagaagta ggataaagac gagactaccg
    35461 atgattccta gcaagagact gacagacaac tcatagggcc taatcagaac tcgggatagg
    35521 atatcgcaag ccagaactag attggcacca accagtgcga ccatgagttt ggtttgactt
    35581 agattatctc catagcgctt gcgaacaaga ttgggaacga taactccgag aaatggtaag
    35641 ccacccacgg taatcatggt gacgcttgtc gttagcgcca ccagaaagag ggccagtttt
    35701 tcaagtaggg agtaggaaat ccccaaaccc tcgctggttt ctttccccag attcatgatg
    35761 gtgaaggttt gggataattt ccaaacggtt atcaggatga tgaggcctaa gaagagccac
    35821 tcatactgat gggtctgaat catggagaag gagccctggg tccaggcagt catactctga
    35881 accagattga aacgataggc gataacttct gtgactgagc cgataatccc gctatagatg
    35941 atcccaatca gaggcaacat ccacctttcc tttacagtaa aaatggtcat aaaggctagg
    36001 aagaagaggg tgaatacgat ggatgaaaca aaagcgaaga gcatcttttg ggtcagacta
    36061 gccgatggaa agacaaaaag gctcagcacc attcccagtt tggcggcttc agtcgttcca
    36121 actgtactcg gtgcagcaaa ctgattttgg gtaatagtct gcatgagaag gcctgccata
    36181 ctcatactag aggcagtcag gagaatactg atagttcttg ggagacggga ctcttgaaag
    36241 aggagccagg tctgctggtc gaaatcaaat agctttcccc atgaaaaatc actggtccca
    36301 atgctaatag agagaaagac taggagtaga agtaagccaa ttaaataatg agaaagtttc
    36361 ataccccgtc ctttcatgta gatttggtat cgaaagatat ctgcggatat aaatgtaaca
    36421 ttatttttct aatctgtcaa taaaatttct gacaatttaa taaatacaac aaggagagag
    36481 caacaagact ttctcctttg ttatcctatt ctaaaatgtt tttaccttaa tctgataaaa
    36541 taatatcttc gagggagtag ctagccgtcc aatcaagata ttgtttagct tttgaagcat
    36601 ctgctaggac actggctggg tcactagcac gtcgagcaac aatctcgtgt gggatttttt
    36661 aatttagtaa ttcttcagca gttttaaaga tttctttgat agtatagcct tttttagttc
    36721 ctaagttaaa gatttgagaa gaactgtctt cttgaaatag gtagttcatt cctttaacat
    36781 gagcctatgc aaggtccaag acataaatgt aatctcgaat acatgaaccg tcacgtgtat
    36841 cgtagtcatc tccaaatatt tttaagctat catgttgtcc caatgcggtc ttgttgatat
    36901 ttggaatgat gtgagttgga tttttcacac gcagaccgtt tgaagcatcc atttcagccc
    36961 cagcaacatt aaagtaacgg aaaataacat atttccagtc gtagcgattg gccatccagt
    37021 aaatcattcg ttcgcccatc agttttgtct ctgcataagg gttgacaggg tcgagcaggg
    37081 tatcttcagt caccggcttg tcaatacagt tatttccata gagagaagca gtcgaagaga
    37141 acatgatttt ttgaatgcca acttcagata agactttgag aacttggttc ataccagcaa
    37201 cgttggcagt gaagtattta cttggatttt caatactttc gctcacaaca atttcacctg
    37261 cacaatggag gacagcatca atctgatttt cttctaagta agcctttaag gcgctagcat
    37321 cataaacatc cagttcttta aagctagcac gactatccac agccgctcga tttcctgtgg
    37381 agagattatc gaggacatgc acctgatagc cagcatttaa aagagcttta acggtatggg
    37441 agccaatgta gctagtccca cctgtaacaa gaattgtttt ggtcatgatt ttttcctttt
    37501 ctagttttgt actatagtaa attgaaataa gatatgaaca actctattag gaaagtcgaa
    37561 ttaatttcta gaaatgtttc agcagctaca gcgtactatt ccaaactcaa ccaactatat
    37621 atttaaagaa agaagaaagg gaagtcaact attttctgta aatttcatga aaaatccaaa
    37681 caactttgat ggtgtattgt tttttttgtt tggaaataaa tattcgagtt aattttggaa
    37741 tgtttactag attttgcact acatgcaaga gaatactatc cttttctaag atagagcagg
    37801 actaagatac taacttagaa atccaccttc ccactatcct tctcctataa aaagtggtaa
    37861 aatggatgaa agaaagaagg aactgaaatg acaacattat tttcaaaaat taaagaagta
    37921 acagaacttg ctgcagtctc aggtcatgaa gcgcctgtcc gtgcttatct tcgtgaaaag
    37981 ttgacaccgc atgtggatga agtggtgaca gatggcttgg gtggtatttt tggtatcaaa
    38041 cattcagaag ctgtggatgc accgcgcgtc ttggtcgctt ctcatatgga cgaagttggt
    38101 tttatggtca gcgaaatcaa gccagatggt accttccgtg tcgtagaaat cggtggctgg
    38161 aaccccatgg tagttagcag ccaacgtttc aaactcttga ctcgtgatgg tcatgaaatt
    38221 cctgtgattt caggttctgt tcctccgcat ttgactcgtg gaaagggggg accaaccatg
    38281 ccagccattg ccgatatcgt ttttgatggt ggttttgcgg acaaggatga ggcagaaagt
    38341 tttggcatcc gtcctggtga taccatcgta ccagatagtt ctgcaatttt gacagccaat
    38401 gaaaaaaata tcatctcaaa agcttgggat aaccgctacg gtgtcctcat ggtaagcgag
    38461 ctagctgaag ctttatcagg tcaaaaactc ggcaatgaac tctatctggg ttctaacgtc
    38521 caagaagaag ttggtctgcg tggcgctcat acctctacaa ccaagtttga cccagaagtc
    38581 ttcctcgcag ttgattgctc accagcaggt gatgtctacg gtggtcaagg caagattgga
    38641 gatggaacct tgattcgttt ctatgatcca ggtcacttgc ttctcccagg gatgaaggat
    38701 tttcttttga caacggctga agaagctggt atcaagtacc aatactactg tggtaaaggc
    38761 ggaacagatg caggtgcagc tcatctgaaa aatggtggtg tcccatcaac aactatcggt
    38821 gtctgcgctc gttatatcca ttctcaccaa accctctatg caatggatga cttcctagaa
    38881 gcgcaagctt tcttacaagc cttggtgaag aaattggatc gttcaacggt tgatttgatt
    38941 aaacattatt aaaccataag ggaggtggta gggatggcag aaccaaacct agaaagcctt
    39001 ataaaagatc tttacaatca tgctcgacat gatttgagtg aagatttagt tgctgctctc
    39061 ctagagactg ctaaaaaact gcctactaca aatgagcaat tgcaggcagt tcgtctctca
    39121 ggcctggtca atcgtgaatt gctcctaaat cccaaacatc cagcacctga gttgctcaac
    39181 ttggctcgct ttatcaaaag agaagaagcc aagtacagag gaactgcgac ttctgcgctt
    39241 atgtatgagg aactctttaa aatgctttga ttccattgtg gatcaaagca ttttttgtaa
    39301 gatctatctc gtgagcgttc aaatagtagt aacaaggaat catgagaagt cagccgagcc
    39361 catagtagtg aagaaacttc tgtaatggaa gtggagcgaa gtgaggaatc gtcaaacggt
    39421 aggggatagg ctgtttgaag ggtgctacga aaaagatagg gtaaggtgaa attatagcgg
    39481 aatgaaataa gatatgaaca aattgattga ggaaattaaa tgaatttata gaaatctttt
    39541 agcagtcatg gtgtcctatt ccagtttcga aatgctataa atacgaacaa attgattggg
    39601 aaattcaaat cgctttctat caatgtttta gaagatacag tgctctagtc taacttcaat
    39661 atactataaa agaacagatg gaagcaatta tgatttactt ctatctttaa aataaatggt
    39721 ctgataggaa aaatgtgtcc cctcataaaa tataggatag tacgaatgga aggcttttgt
    39781 agactggagg acgaaggagt ttagaaactc tcgttaaaag ttagttgagc cggagtatgg
    39841 tggtgtggat aattatcaaa aattatttct aaatcgaaat agttgacagt tagaacgatg
    39901 agtgttacaa ttgttttatt catttcgata tcgaaataaa ttggaggtgt tatgaaagat
    39961 ggtcatttgc tagcccatca tattcgtttg ttgaatgggc ggatttttca aaagttactg
    40021 agtcaagatc ctgaggctct ttataggggt gaacagggca agattttagc ggttttatgg
    40081 aatagtgaaa ctggctgcgc aactgcgaca gatatcgcgc ttgcgactgg gcttgcgaat
    40141 aatacgctaa cgactatgat aaaaaagcta gaggaacaaa agcttgtaat tgttagtccg
    40201 tgtggaaaag acaagcgtaa gaagtattta gttttaacgg agttaggcaa gtcccagaaa
    40261 gaagtggggc atcgtgtcag tcagaaattg gatactatct tttacaaagg attttcagag
    40321 gaagaaattc accaatttga aggttttcaa gaaagaattt tggcgaattt gaaagagaag
    40381 ggaaatgagg tttagaatat gtcacaacaa gtgaaaaatg ctcacaacct atacatccat
    40441 gccattcaag acggacgagt tgctgaggct caagcccagt ctgtagggga tacctatatc
    40501 caacattcga caggtgttcc tgacgggaaa gaaggatttg cagccttctt tgcagatttc
    40561 tttgagcgtc atccagagcg tcagattaag attgtccgca ccattgagga tggcaatctg
    40621 gtctttgttc atgttcatca atatctgaat ggtggagaag ctcaatgggt gacgacggat
    40681 actttccgtg cggatgagaa tggtcgtatt gttgagcatt gggatgtcat tgactactat
    40741 cgaacacctg aaaatgatca actagatcaa atttttggag attttgaaat caaggatttg
    40801 gacaagaaag cagaaaataa aaaactggtt cgccgtttct tgacagaaat tttccaaaat
    40861 ggggagctag agcagtggag tgattatgtg gcagacgatt tgattcagca taatcatgag
    40921 attggacaag gaagtgctgc ttataaaaac tatgtggctg aatatagtgt cacttttgac
    40981 tttgttttcc aactcttagg acaaggaaac tatgtggtta gctatggtca gactcagatt
    41041 gatggcgttg cttatgccca gtacgatatc ttccgtttag agaacgggaa aattgtggag
    41101 cattgggata ataaggaagt catgcctaag gtagaagact tgactaatcg agggaagttt
    41161 taaattgagg acaaagaatg attgaataca aaaatgtagc actgcgctac acagaaaagg
    41221 atgtcttgag agatgtcaac ttacagattg aggatgggga atttatggtt ttagtagggc
    41281 cttctgggtc aggtaagacg accatgctca agatgattaa ccgtcttttg gaaccaactg
    41341 atggaaatat ttatatggat gggaagcgca tcaaagacta tgatgagcgt gaacttcgtc
    41401 tttctactgg ttatgtttta caggctattg ctctttttcc aaatctaaca gttgcggaaa
    41461 atattgctct cattcctgaa atgaaggggt ggagcaagga agaaattacg aagaaaacag
    41521 aagagctttt ggctaaggtt ggtttaccag tagccgagta tgggcatcgc ttacctagtg
    41581 aattatctgg tggagaacag caacgggtcg gtattgtccg agctatgatt ggtcagccca
    41641 agattttcct catggatgaa cccttttcgg ccttggatgc tatttcgaga aaacagttgc
    41701 aggttctgac aaaagaattg cataaagagt ttgggatgac aacgattttt gtaacccatg
    41761 atacggatga agccttgaag ttggcggacc gtattgctgt cttgcaggat ggagaaattc
    41821 gccaggtagc gaatcccgag acaattttaa aagtgcctgc aacagacttt gtagcagact
    41881 tgtttggagg tagtgttcat gactaattta attgcaactt ttcaggatcg ttttagtgat
    41941 tggttgacag ctctatctca acatttgcag ttgtcacttt tgaccttgtt actagctatt
    42001 ttgcttgcga ttcccttggc tgtttttctt cgctatcatg agaagctggc cgactgggtc
    42061 ttgcagattg caggtatttt ccagaccatc ccgtctctgg ccttgttggg gctctttatc
    42121 cctttgatgg gaattgggac cttgccggct ttgacagctc tagtgattta tgcgattttt
    42181 ccgattttac aaaatactat tactgggctg aagggaattg atccgagtct tcaagaggct
    42241 gggattgcct ttgggatgac cagatgggag cgtctcaaga agtttgaaat tccacttgcc
    42301 atgcctgtta tcatgtctgg aattcggacg gcagcggtct tgattatcgg tacggctacc
    42361 ttggcgacct tgattggggc agggggactg ggttccttta tcctgttggg aattgaccgt
    42421 aataatgcca gtttgatttt gattggggcc ctttcttctg cagtgctagc tattgccttt
    42481 aacttcctac taaaagtaat ggaaaaagcg aaattgcgga cgattttctc tggttttgcc
    42541 ttggtggctt tattactggg tctgtcttat agtccagccc ttttggctca aaaagagaag
    42601 gaaaacttga ttattgctgg gaaaataggc ccagaaccag aaattttggc taatatgtat
    42661 aaattgctga ttgaagaaaa taccagcatg actgcgactg ttaaaccgaa ttttgggacg
    42721 acaagtttcc tttatgaagc tctgaaaaaa ggtgatattg acatttatcc tgaatttacc
    42781 ggtacggtga ctgaaagttt gcttcaacca tcacccaagg tgagtcatga gccagagcag
    42841 gtttatcaag tggcgcgtga tggcattgcc aagcaggatc atctagccta tctcaaacct
    42901 atgtcttatc aaaataccta tgctgtagct gttccgaaaa agattgctca agaatatggc
    42961 ttgaagacca tttcggattt gaaaaaagtg gaagggcagc tgaaggcagg ctttacgctt
    43021 gagtttaacg accgtgaaga tggaaataag ggcttgcaat caatgtatgg tctcaatctc
    43081 aatgtggcga ctatgcagcc agctcttcgt tatcaggcaa ttcagtcagg ggatattcaa
    43141 atcacggatg cctattcgac tgatgcggaa ttggagcgtt atgatttaca ggtcttggaa
    43201 gatgacaagc aactcttccc accttatcaa ggggctccac tcatgaaaga agctcttctc
    43261 aagaaacacc cagagttgga aagagttctt aatacattgg ctggtaagat tacagaaagc
    43321 cagatgagcc agctcaacta ccaagtcggt gttgaaggca agtcagcaaa gcaagtagcc
    43381 aaggagtttc tccaagaaca aggtttgttg aagaaatgat gggacagaga ctt
//
LOCUS       DAVBOD010000012        42876 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 640-05
            SAMEA1012484-rid20186543.denovo.012, whole genome shotgun sequence.
ACCESSION   DAVBOD010000012 DAVBOD010000000
VERSION     DAVBOD010000012.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012484
            Sequence Read Archive: ERR059358
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 42876)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 42876)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979948.1
            Genome Coverage       :: 595x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:03:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,266
            CDSs (total)                      :: 2,219
            Genes (coding)                    :: 2,091
            CDSs (with protein)               :: 2,091
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 71 of 128
            Pseudo Genes (incomplete)         :: 50 of 128
            Pseudo Genes (internal stop)      :: 33 of 128
            Pseudo Genes (multiple problems)  :: 22 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..42876
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012484-rid20186543.denovo.012"
                     /strain="NIG 640-05"
                     /db_xref="taxon:1313"
     gene            complement(1..1959)
                     /gene="ftsH"
                     /locus_tag="VQ862_000705"
     CDS             complement(1..1959)
                     /gene="ftsH"
                     /locus_tag="VQ862_000705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000744538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent zinc metalloprotease FtsH"
                     /protein_id="HET3115085.1"
                     /translation="MKKQNNGLIKNPFLWLLFIFFLVTGFQYFYSGNNSGGSQQINYT
                     ELVQEITDGNVKELTYQPNGSVIEVSGVYKNPKTSKEETGIQFFTPSVTKVEKFTSTI
                     LPADTTVSELQKLATDHKAEVTVKHESSSGIWINLLVSIVPFGILFFFLFSMMGNMGG
                     GNGRNPMSFGRSKAKAANKEDIKVRFSDVAGAEEEKQELVEVVEFLKDPKRFTKLGAR
                     IPAGVLLEGPPGTGKTLLAKAVAGEAGVPFFSISGSDFVEMFVGVGASRVRSLFEDAK
                     KAAPAIIFIDEIDAVGRQRGVGLGGGNDEREQTLNQLLIEMDGFEGNEGIIVIAATNR
                     SDVLDPALLRPGRFDRKVLVGRPDVKGREAILKVHAKNKPLAEDVDLKLVAQQTPGFV
                     GADLENVLNEAALVAARRNKSIIDASDIDEAEDRVIAGPSKKDKTVSQKERELVAYHE
                     AGHTIVGLVLSNARVVHKVTIVPRGRAGGYMIALPKEDQMLLSKEDMKEQLAGLMGGR
                     VAEEIIFNVQTTGASNDFEQATQMARAMVTEYGMSEKLGPVQYEGNHAMFGAQSPQKS
                     ISEQTAYEIDEEVRSLLNEARNKAAEIIQSNREIHKLIAEALLKYETLDSTQIKALYE
                     TGKMPEAVEEESHALSYDEVKSKMNDEK"
     gene            complement(1975..2517)
                     /gene="hpt"
                     /locus_tag="VQ862_000706"
     CDS             complement(1975..2517)
                     /gene="hpt"
                     /locus_tag="VQ862_000706"
                     /EC_number="2.4.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypoxanthine phosphoribosyltransferase"
                     /protein_id="HET3115086.1"
                     /translation="MLENDIKKVLVSHDEITEAAKKLGAQLTKDYAGKNPILVGILKG
                     SIPFMAELVKHIDTHIEMDFMMVSSYHGGTASSGVINIKQDVTQDIKGRHVLFVEDII
                     DTGQTLKNLRDMFKAREAASVKIATLLDKPEGRVVEIEADYTCFTIPNEFVVGYGLDY
                     KENYRNLPYIGVLKEEVYSN"
     gene            complement(2521..3798)
                     /gene="tilS"
                     /locus_tag="VQ862_000707"
     CDS             complement(2521..3798)
                     /gene="tilS"
                     /locus_tag="VQ862_000707"
                     /EC_number="6.3.4.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA lysidine(34) synthetase TilS"
                     /protein_id="HET3115087.1"
                     /translation="MREPDFLNHFLKKGYFKKHAKAVLALSGGLDSMFLFKVLSTYQK
                     ELEIELILAHVNHKQRIESDWEEKELRKLAAEAELPIYISNFSGEFSEARARNFRYDF
                     FQEVMKKTGATALVTAHHADDQVETILMRLIRGTRLRYLSGIKEKQVVGEIEIIRPFL
                     HFQKKDFPSIFHFEDTSNQENHYFRNRIRNSYLPELEKENPRFRDAILGIGNEILDYD
                     LAIAELSNNINVEDLQQLFSYSESTQRVLLQTYLNRFPDLNLTKAQFAEVQQILKSKS
                     QYRHPIKNGYELIKEYQQFQICKISPQADEEEDELVLHYQNQVAYQGYLFSFGLPLEG
                     ESIQQIPVSRETSIHIRHRKTGDVLIQNGHRKKLRRLFIDLKIPMEKRNSALIIEQFG
                     EIVSILGIATNNLSKKTKNDIMNTVLYIEKIDR"
     gene            complement(3795..5063)
                     /locus_tag="VQ862_000708"
     CDS             complement(3795..5063)
                     /locus_tag="VQ862_000708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001224749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class A beta-lactamase-related serine hydrolase"
                     /protein_id="HET3115088.1"
                     /translation="MRKFLIILLLPSFLTISKVVSTEKEVVYTSKEIYYLSQSDFGIY
                     FREKLSSPMVYGEVPVYANEDLVVESGKLTPKTSFQITEWRLNKQGIPVFKLSNHQFI
                     AADKRFLYDQSEVTPTIKKAWLESDFKLYNSPYDLKEVKSSLSAYSQVSIDKTMFVEG
                     REFLHIDQAGWVAKESTSEEDNRMSKVQEMLSEKYQKDSFSIYVKQLTTGKEAGINQD
                     EKMYAASVLKLSYLYYTQEKINEGLYQLDTTVKYVSAVNDFPGSYKPEGSGSLPKKED
                     NKEYSLKDLITKVSKESDNVAHNLLGYYISNQSDATFKSKMSAIMGDDWDPKEKLISS
                     KMAGKFMEAIYNQNGFVLESLTKTDFDSQRIAKGVSVKVAHKIGDADEFKHDTGVVYA
                     DSPFILSIFTKNSDYDTISKIAKDVYEVLK"
     gene            complement(5183..5551)
                     /locus_tag="VQ862_000709"
     CDS             complement(5183..5551)
                     /locus_tag="VQ862_000709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation initiator family protein"
                     /protein_id="HET3115089.1"
                     /translation="MSKNIVQLNNSFIQNEYQRRRYLMKERQKRNRFMGGVLILIMLL
                     FILPTFNLAQSYQQLLQRRQQLADLQTQYQTLSDEKDKETAFATKLKDEDYAAKYTRA
                     KYYYSKSREKVYTIPDLLQR"
     gene            complement(5544..5810)
                     /locus_tag="VQ862_000710"
     CDS             complement(5544..5810)
                     /locus_tag="VQ862_000710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001234972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding S4 domain-containing protein"
                     /protein_id="HET3115090.1"
                     /translation="MRLDKYLKVSRIIKRRTVAKEVADKGRIKVNGILAKSSTDLKVN
                     DQVEIRFGNKLLLVKVLEMKDSTKKEDAAGMYEIISETRVEENV"
     gene            complement(5868..9377)
                     /gene="mfd"
                     /locus_tag="VQ862_000711"
     CDS             complement(5868..9377)
                     /gene="mfd"
                     /locus_tag="VQ862_000711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000258090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription-repair coupling factor"
                     /protein_id="HET3115091.1"
                     /translation="MVTLLDLFSENDQIKKWHQNLTDKKRQLILGLSTSTKALAIASS
                     LEKEDRIVLLTSTYGEAEGLVSDLISILGEELVYPFLVDDAPMVEFLMSSQEKIISRV
                     EALRFLTDSSKKGILVCNIAASRLILPSPNAFKDSIVKISVGEEYAQHAFIHQLKENG
                     YRKVTQVQTQGEFSLRGDILDIFEISQLEPCRIEFFGDEIDGIRSFEVETQLSKENKT
                     ELTIFPASDMLLREKDYQRGQSALEKQISKTLSPILKSYLEEILSSFHQKQSHADSRK
                     FLSLCYDKTWTVFDYIEKDTPIFFDDYQKLMNQYEVFERELAQYFTEELQNSKAFSDM
                     QYFSDIEQIYKKQSPVTFFSNLQKGLGNLKFDKIYQFNQYPMQEFFNQFSFLKEEIER
                     YKKMDYTIILQSSNSMGSKTLEDMLEEYQIKLDSRDKTSICKESVNLIEGNLRHGFHF
                     VDEKILLITEHEIFQKKLKRRFRRQHVSNAERLKDYNELEKGDYVVHHIHGIGQYLGI
                     ETIEIKGIHRDYVSVQYQNGDQISIPVEQIHLLSKYISSDGKAPKLNKLNDGHFKKAK
                     QKVKNQVEDIADDLIKLYSERSQLKGFAFSADDDDQDAFDDAFPYVETDDQLRSIEEI
                     KRDMQASQPMDRLLVGDVGFGKTEVAMRAAFKAVNDHKQVVILVPTTVLAQQHYTNFK
                     ERFQNFAVNVDVLSRFRSKKEQTATLEKLKNGQVDILIGTHRVLSKDVVFADLGLMII
                     DEEQRFGVKHKETLKELKKQVDVLTLTATPIPRTLHMSMLGIRDLSVIETPPTNRYPV
                     QTYVLEKNDSVIRDAVLREMERGGQVYYLYNKVDTIVQKVSELQELIPEASIGYVHGR
                     MSEVQLENTLLDFIEGQYDILVTTTIIETGVDIPNANTLFIENADHMGLSTLYQLRGR
                     VGRSNRIAYAYLMYRPEKSISEVSEKRLEAIKGFTELGSGFKIAMRDLSIRGAGNLLG
                     KSQSGFIDSVGFELYSQLLEEAIAKRNGNANANTRTKGNAELILQIDAYLPDTYISDQ
                     RHKIEIYKKIRQIDNRVNYEELQEELIDRFGEYPDVVAYLLEIGLVKSYLDKVFVQRV
                     ERKDNKITIQFEKVTQRLFLAQDYFKALSVTNLKAGIAENKGLMELVFDVQNKKDYEI
                     LEGLLIFGESLLEIKESKEENSI"
     gene            complement(9378..9947)
                     /locus_tag="VQ862_000712"
     CDS             complement(9378..9947)
                     /locus_tag="VQ862_000712"
                     /EC_number="3.1.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA hydrolase"
                     /protein_id="HET3115092.1"
                     /translation="MTKLLVGLGNPGDKYFETKHNVGFMLIDQLAKKQNVTFTHDKIF
                     QADLASFFLNGEKIYLVKPTTFMNESGKAVHALLTYYGLDIDDLLIIYDDLDMEVGKI
                     RLRAKGSAGGHNGIKSIIQHIGTQVFNRVKIGIGRPKNGMSVVHHVLSKFDRDDYIGI
                     LQSVDKVDDSVNYYLQEKNFEKTMQRYNG"
     gene            complement(10018..11133)
                     /gene="ychF"
                     /locus_tag="VQ862_000713"
     CDS             complement(10018..11133)
                     /gene="ychF"
                     /locus_tag="VQ862_000713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002269933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-regulated ATPase YchF"
                     /protein_id="HET3115093.1"
                     /translation="MALTAGIVGLPNVGKSTLFNAITKAGAEAANYPFATIDPNVGMV
                     EVPDERLQKLTEMITPKKTVPTTFEFTDIAGIVKGASKGEGLGNKFLANIREVDAIVH
                     VVRAFDDENVMREQGREDAFVDPLADIDTINLELILADLESVNKRYARVEKMARTQKD
                     KESVAEFNVLQKIKPVLEDGKSARTIEFTDEEQKVVKGLFLLTTKPVLYVANVDEDVV
                     SEPDSIDYVKQIREFAATENAEVVVISARAEEEISELDDEDKKEFLEAIGLTESGVDK
                     LTRAAYHLLGLGTYFTAGEKEVRAWTFKRGMKAPQAAGIIHSDFEKGFIRAVTMSYED
                     LVKYGSEKAVKEAGRLREEGKEYIVQDGDIMEFRFNV"
     gene            complement(11217..11411)
                     /locus_tag="VQ862_000714"
     CDS             complement(11217..11411)
                     /locus_tag="VQ862_000714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF951 family protein"
                     /protein_id="HET3115094.1"
                     /translation="MYQVGNFVEMKKPHACTIKSTGKKANRWEITRVGADIKIKCSNC
                     EHVVMMGRYDFERKMNKIID"
     gene            complement(11476..12612)
                     /gene="dnaN"
                     /locus_tag="VQ862_000715"
     CDS             complement(11476..12612)
                     /gene="dnaN"
                     /locus_tag="VQ862_000715"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000581170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit beta"
                     /protein_id="HET3115095.1"
                     /translation="MIHFSINKNLFLQALNTTKRAISSKNAIPILSTVKIDVTNEGIT
                     LIGSNGQISIENFISQKNEDAGLLITSLGSILLEASFFINVVSSLPDVTLDFKEIEQN
                     QIVLTSGKSEITLKGKDSEQYPRIQEISASTPLILETKLLKKIINETAFAASTQESRP
                     ILTGVHFVLSQHKELKTVATDSHRLSQKKLTLEKNSDDFDVVIPSRSLREFSAVFTDD
                     IETVEIFFANNQILFRSENISFYTRLLEGNYPDTDRLIPTDFNTTITFNVVNLRQSME
                     RARLLSSATQNGTVKLEIKDGVVSAHVHSPEVGKVNEEIDTDQVTGEDLTISFNPTYL
                     IDSLKALNSEKVTISFISAVRPFTLVPADTDEDFMQLITPVRTN"
     gene            complement(12771..14132)
                     /gene="dnaA"
                     /locus_tag="VQ862_000716"
     CDS             complement(12771..14132)
                     /gene="dnaA"
                     /locus_tag="VQ862_000716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosomal replication initiator protein DnaA"
                     /protein_id="HET3115096.1"
                     /translation="MKEKQFWNRILEFAQERLTRSMYDFYAIQAELIKVEENVATIFL
                     PRSEMEMVWEKQLKDIIVVAGFEIYDAEITPHYIFTKPQDTTSSQVEEATNLTLYDYS
                     PKLVSIPYSDTGLKEKYTFDNFIQGDGNVWAVSAALAVSEDLALTYNPLFIYGGPGLG
                     KTHLLNAIGNEILKNIPNARVKYIPAESFINDFLDHLRLGEMEKFKKTYRSLDLLLID
                     DIQSLSGKKVATQEEFFNTFNALHDKQKQIVLTSDRSPKHLEGLEERLVTRFSWGLTQ
                     TITPPDFETRIAILQSKTEHLGYNFQSDTLEYLAGQFDSNVRDLEGAINDITLIARVK
                     KIKDITIDIAAEAIRARKQDVSQMLVIPIDKIQTEVGNFYGVSIKEMKGSRRLQNIVL
                     ARQVAMYLSRELTDNSLPKIGKEFGGKDHTTVIHAHAKIKSLIDQDDNLRLEIESIKK
                     KIK"
     gene            complement(14345..15103)
                     /locus_tag="VQ862_000717"
     CDS             complement(14345..15103)
                     /locus_tag="VQ862_000717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000410347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB/RepB/Spo0J family partition protein"
                     /protein_id="HET3115097.1"
                     /translation="MEKFEMISITDIQKNPYQPRKEFDREKLDELAQSIKENGVIQPI
                     IVRQSPVIGYEILAGERRYRASLLAGLRSIPAVVKQISDQEMMVQSIIENLQRENLNP
                     IEEARAYESLVEKGFTHAEIADKMGKSRPYISNSIRLLSLPEQILSEVENGKLSQAHA
                     RSLVGLNKEQQDYFFQRIIEEDISVRKLEALLTEKKQKKQQKTNHFIQNEEKQLRKLL
                     GLDVEIKLSKKDSGKIIISFSNQEEYSRIINSLK"
     gene            complement(15161..16342)
                     /locus_tag="VQ862_000718"
     CDS             complement(15161..16342)
                     /locus_tag="VQ862_000718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000681590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine protease"
                     /protein_id="HET3115098.1"
                     /translation="MKHLKTFYKKWFQLLVVIVISFFSGALGSFSITQLTQKSSVNNS
                     NNNSTITQTAYKNENSTTQAVNKVKDAVVSVITYSANRQNSVFGNDDTDTDSQRISSE
                     GSGVIYKKNDKEAYIVTNNHVINGASKVDIRLSDGTKVPGKIVGADTFSDIAVVKISS
                     EKVTTVAEFGDSSKLTVGETAIAIGSPLGSEYANTVTQGIVSSLNRNVSLKSEDGQAI
                     STKAIQTDTAINPGNSGGPLINIQGQVIGITSSKIATNGGTSVEGLGFAIPANDAINI
                     IEQLEKNGKVTRPALGIQMVNLSNVSTSDIRRLNIPSNVTSGVIVRSVQSNMPANGHL
                     EKYDVITKVDDKEIASSTDLQSALYNHSIGDTIKITYYRNGKEETTSIKLNKSSGDLE
                     S"
     gene            16525..17004
                     /gene="rlmH"
                     /locus_tag="VQ862_000719"
     CDS             16525..17004
                     /gene="rlmH"
                     /locus_tag="VQ862_000719"
                     /EC_number="2.1.1.177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000695929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (pseudouridine(1915)-N(3))-methyltransferase RlmH"
                     /protein_id="HET3115099.1"
                     /translation="MKIKVVTVGKLKEKYLKDGIAEYSKRISRFAKFEMIELSDEKTP
                     DKASESENQKILEIEGQRILSKIADRDFVIVLAIEGKTFFSEEFSKQLEETSIKGFST
                     LTFIIGGSLGLSSSVKNRANLSVSFGRLTLPHQLMRLVLVEQIYRAFTIQQGFPYHK"
     gene            17048..17121
                     /locus_tag="VQ862_000720"
     tRNA            17048..17121
                     /locus_tag="VQ862_000720"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:17082..17084,aa:Arg,seq:tct)
     gene            17286..17411
                     /gene="comC"
                     /locus_tag="VQ862_000721"
     CDS             17286..17411
                     /gene="comC"
                     /locus_tag="VQ862_000721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000799689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence-stimulating peptide ComC"
                     /protein_id="HET3115100.1"
                     /translation="MKNTVKLEQFVALKEKDLQKIKGGEMRLSKFFRDFILQRKK"
     gene            17432..18757
                     /locus_tag="VQ862_000722"
     CDS             17432..18757
                     /locus_tag="VQ862_000722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000362880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HET3115101.1"
                     /translation="MDLFGFGTVIVHFLIISHSYHFICKGQINRKELFVFGAYTLLTE
                     IVFDFPLYILYLDGLGIERFLFPLGLYSYFRWMKQYERDRGLFLSLLLSLLYESTHNF
                     LSVTFSSITGDNFVLQYHFPFFFVVTVLTYFVTLKIIYYFHLELAYFDEDYLYPFLKK
                     VFFALLLLHIVSFVSDMVSTIKHLNSFGSILSSIVFISLLLTFFAMNSHKVQMEKEIA
                     LKQKKFEQKHLQNYTDEIVGLYNEIRGFRHDYAGMLVSMQMAIDSGNLQEIDRIYNEV
                     LVKANHKLRSDKYTYFDLNNIEDSALRSLVAQSIVYARNNGVEFTLEVKDTITKLPIE
                     LLDLVRIMSVLLNNAVEGSADSYKKQMEVAVIKMETETVIVIQNSCKMTMTPSGDLFA
                     LGFSTKGRNRGVGLNNVKELLDKYNNIILETEMEGSTFRQIIRFKREFE"
     gene            18754..19506
                     /locus_tag="VQ862_000723"
     CDS             18754..19506
                     /locus_tag="VQ862_000723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000866085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET3115102.1"
                     /translation="MKVLILEDVIEHQVRLERILDEISKESNIPISYKTTGKVREFEE
                     YIENDEVNQLYFLDIDIHGIEKKGFEVAQLIRHYNPYAIIVFITSRSEFATLTYKYQV
                     SALDFVDKDINDEMFKKRIEQNIFYTKSMLLENEDVVDYFDYNYKGNDLKIPYHDILY
                     IETTGVSHKLRIIGKNFAKEFYGTMTDIQEKDKHTQRFYSPHKSFLVNIGNIREIDRK
                     NLEIVFYEDHRCPISRLKIRKLKDILEKKSQK"
     gene            19558..19629
                     /locus_tag="VQ862_000724"
     tRNA            19558..19629
                     /locus_tag="VQ862_000724"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:19591..19593,aa:Glu,seq:ttc)
     gene            19635..19708
                     /locus_tag="VQ862_000725"
     tRNA            19635..19708
                     /locus_tag="VQ862_000725"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:19669..19671,aa:Asn,seq:gtt)
     gene            complement(19749..20291)
                     /locus_tag="VQ862_000726"
     CDS             complement(19749..20291)
                     /locus_tag="VQ862_000726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator
                     C-terminal domain-containing protein"
                     /protein_id="HET3115103.1"
                     /translation="MQESNKRLKTKRTIENAMVQLLMEQPFDKISTVKLVEKAGISRS
                     SFYTHYKDKYDMIEHYQSKLFHTFEYIFQKHAHHKRDAILEVFEYLESEPLLAALLSE
                     NGTKEIQNFLRNKLHIMLSTDLQKRFMQLNLNTTELEYSSIYLTHALFGVCQTWIAHG
                     KKESSQEITDFLMKMLGDTN"
     gene            20470..21237
                     /locus_tag="VQ862_000727"
     CDS             20470..21237
                     /locus_tag="VQ862_000727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhgE/Pip domain-containing protein"
                     /protein_id="HET3115104.1"
                     /translation="MIGISLIPDLYNIIFLSSMWDPYGQLSDLPVAVVNNDKEASYNG
                     NTMAIGKDTVSNLKENKTLDFHFVDEEEGKKGLEDGDYYMVVTLPSDLSEKTTTLSNI
                     QSTAAYQSLTSEQQTEISDSVSQNSTDSIQSAQSIVALVQDLQGSLENLQNQSSNLST
                     LKNQSNQVSPITSTSLIGLSSGLTEIQGDVTSKLVPASQSIASGVNAYTTGVDKVSQG
                     ASQLSEKNATLTGSLDKLVSGSNTLTQKSSRLTAGVG"
     gene            21241..21660
                     /locus_tag="VQ862_000728"
                     /pseudo
     CDS             21241..21660
                     /locus_tag="VQ862_000728"
                     /inference="COORDINATES: protein motif:HMM:TIGR03057.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            21688..22002
                     /locus_tag="VQ862_000729"
     CDS             21688..22002
                     /locus_tag="VQ862_000729"
                     /inference="COORDINATES: protein motif:HMM:TIGR03062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhgE/Pip family protein"
                     /protein_id="HET3115105.1"
                     /translation="MAGILVYGGVQLIGLTANHEMRIFILIILTSLVFMSMVTTLATW
                     NSRIGAFFSLILLLLQLASSAGTYPLALTNDFFRSINPWLPMSYSVSGLRQTISINKS
                     FS"
     gene            complement(22103..24655)
                     /locus_tag="VQ862_000730"
     CDS             complement(22103..24655)
                     /locus_tag="VQ862_000730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfhO family protein"
                     /protein_id="HET3115106.1"
                     /translation="MKSFLKTYRTYFISLIIPVVIMSGVYLSQGIYWNSDNSPLLGDG
                     FHQYVIFDVALRNILHGNSSLFYTFTSGLGLNFYALSSYYLGSFLAPLVYFFDLTNMP
                     DAVYLTTLLKFGLIGLSTFFSLNKLFQSIPQTLKLALSTSYALMSFTVSQLEIKTWLD
                     VFILIPLIITGLHLLITEKKLLLYFTSLSILFIQNYYFGYMTVLFLIFWYLCQISWDF
                     KTRKSSVLDFIVISFLAGMASLIMTLPTLFDLQTHGEKLTEVTKFQTESSWYLDLFAK
                     QFIGSFDTTKYGAIPMIFVGLFPFILTILFFTLKSIKFHVKLIYVIFFAFLIASFYIE
                     ALDLFWQGMHTPNMFLHRYAWIFSTLLIYTAAEVLKRLKELKVWNFLVSLFLVVAGFL
                     ATIYLKSHYSFLTDLNILLTLEFLVVYSLLLLAVIKKFISVNLFAILISLFILVEMSL
                     NASSQMDGIAKEWGFASRSAYSRDILAMESFSTYIGNQFTRTEKLQTQTGNDSMKFNY
                     NGISQFSSVRNRSSSSTLDKLGFKSSGTNLNLRYANNSILADSLFGIQYNISDSPIDK
                     YGFKDIYQKDNLTLYENQYSLPIAVASQSVYNDVKFNEHTLDNQASFLNQLANVNFDY
                     FSPIPYEKTEKIENTNDLISVTSSSNEDAAIQYQIEVPENSQVYLSFINLHFSNDKQK
                     KVDILVNGEKKTFTTDNVFSFFNLGYTKEKKTFNINVSFPGNSQVSFESPTFYRLDTK
                     TFTEAIQKIKEQPVTVSTSKNKVFATYDVQQDTSIFFTIPYDKGWSAYQDGKKIEIKQ
                     AQTGFMKVDIPKGKGTITLSFIPNGFITGAICSFTSLLLFGIYNHRRKSSKA"
     gene            complement(24717..26339)
                     /locus_tag="VQ862_000731"
     CDS             complement(24717..26339)
                     /locus_tag="VQ862_000731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HET3115107.1"
                     /translation="MLTVSDVSLRFSDRKLFDDVNIKFTEGNTYGLIGANGAGKSTFL
                     KILAGDIEPTTGHISLGPDERLSVLRQNHFDYEDERAIDVVIMGNEKLYSIMKEKDAI
                     YMKEDFSDEDGVRAAELEGEFAELGGWEAESEASQLLQNLNIPEELHYQNMSELANGE
                     KVKVLLAKALFGKPDVLLLDEPTNGLDIQSITWLEDFLIDFDNTVIVVSHDRHFLNKV
                     CTHMADLDFGKIKLYVGNYDFWKESSELAAKLLADRNAKAEEKIKQLQEFVARFSANA
                     SKSRQATSRKKMLDKIELEEIVPSSRKYPFINFKAEREIGNDLLTVENLTVKIDGETI
                     LDNISFILRPDDKTALIGQNDIQTTALIRAIMGDIDYEGTVKWGVTTSQSYLPKDNSA
                     DFAGGESILDWLRQFASKEEDDNTFLRGFLGRMLFSGDEVNKPVNVLSGGEKVRVMLS
                     KLMLLKSNVLVLDDPTNHLDLESISSLNDGLKNFKESIIFASHDHEFIQTLANHIIVL
                     SKNGVIDRIDETYDEFLENAEVQAKVKELWKD"
     gene            26545..27570
                     /gene="trpS"
                     /locus_tag="VQ862_000732"
     CDS             26545..27570
                     /gene="trpS"
                     /locus_tag="VQ862_000732"
                     /EC_number="6.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000165445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan--tRNA ligase"
                     /protein_id="HET3115108.1"
                     /translation="MTKPIILTGDRPTGKLHIGHYVGSLKNRVLLQEEDKYDMFVFLA
                     DQQALTDHAKDPQTIVESIGNVALDYLAVGLDPNKSTIFIQSQIPELAELSMYYMNLV
                     SLARLERNPTVKTEISQKGFGESIPTGFLVYPIAQAADITAFKANYVPVGTDQKPMIE
                     QTREIVRSFNNAYNCDVLVEPEGIYPENERAGRLPGLDGNAKMSKSLNNGIYLADDAD
                     TLRKKVMSMYTDPDHIRVEDPGKIEGNMVFHYLDVFGRPEDAQEIADMKERYQRGGLG
                     DVKTKRYLLEILERELGPIRERRIEFAKDMGEVYNMIQKGSERAREVAGQTLSEVKGA
                     MGLHYFN"
     gene            27722..29200
                     /gene="guaB"
                     /locus_tag="VQ862_000733"
     CDS             27722..29200
                     /gene="guaB"
                     /locus_tag="VQ862_000733"
                     /EC_number="1.1.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000073411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IMP dehydrogenase"
                     /protein_id="HET3115109.1"
                     /translation="MSNWDTKFLKKGFTFDDVLLIPAESHVLPNDADLTTKLADNLTL
                     NIPIITAAMDTVTESQMAIAIARAGGLGVIHKNMSIAQQADEVRKVKRSENGVIIDPF
                     FLTPEHTIAEADELMGRYRISGVPVVETLENRKLVGILTNRDLRFISDYNQPISNHMT
                     SENLVTAPVGTDLATAESILQEHRIEKLPLVDEEGSLSGLITIKDIEKVIEFPNAAKD
                     EFGRLLVAGAVGVTSDTFERAEALFEAGADAIVIDTAHGHSAGVLRKIAEIRAHFPDR
                     TLIAGNIATAEGARALYEAGVDVVKVGIGPGSICTTRVIAGVGVPQVTAIYDAAAVAR
                     EYGKTIIADGGIKYSGDIVKALAAGGNAVMLGSMFAGTDEAPGETEIFQGRKFKTYRG
                     MGSIAAMKKGSSDRYFQGSVNEANKLVPEGIEGRVAYKGAAADIVFQMIGGIRSGMGY
                     CGAANLKELHDNAQFIEMSGAGLKESHPHDVQITNEAPNYSM"
     gene            complement(29251..30348)
                     /gene="recF"
                     /locus_tag="VQ862_000734"
     CDS             complement(29251..30348)
                     /gene="recF"
                     /locus_tag="VQ862_000734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000266665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication/repair protein RecF"
                     /protein_id="HET3115110.1"
                     /translation="MWLQHLSLKTFRNYKETKIDFNPKLNVFLGRNAQGKTNMLEAIY
                     FLALTRSHRTRTDKNLIHFDEEQLHLSGLVQKKTGSIPLEIELTQKGRVTKVNHLKQA
                     RLSDYVGHMNVVLFAPEDLQLIKGAPSIRRKFIDMELGQIKPIYLSDLTNYNHILKQR
                     NTYLKSAQKIDETFLSVLDDQLVDYGCRVMNHRLDFIKKLESFGRKKHFELSNQIEEL
                     SISYQSSVNITDKQNLSESFKIALEKSRSRDLFKKNTGVGPHRDDISFYINGMDASFG
                     SQGQHRSLVLSIKLAEIELMESITTESPILLLDDVMSELDNTRQLKLLETISQSIQTF
                     ITTTSLDHLQNLPENLSIFTIQDGKASVNGN"
     gene            complement(30351..30719)
                     /gene="yaaA"
                     /locus_tag="VQ862_000735"
     CDS             complement(30351..30719)
                     /gene="yaaA"
                     /locus_tag="VQ862_000735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S4 domain-containing protein YaaA"
                     /protein_id="HET3115111.1"
                     /translation="MEYKLFEEFITLQALLKELGITHSGGAIKSFLSEHSVYFNRELE
                     SRRGKKLRIGDKVDIPDMNIDILLTQPTSEEQDEYQADKVEKERIAKLVKKMNKGVKK
                     DKSKPASSPKSQQAPRFPGR"
     gene            30878..32128
                     /locus_tag="VQ862_000736"
     CDS             30878..32128
                     /locus_tag="VQ862_000736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HET3115112.1"
                     /translation="MELVHGISTHFIQSKKFKTNKITVRFTAPLSLDTIAGHMLSASM
                     LETANQMYPTSQDLRRHLASLYGTDMSTNCFRRGQSHIIELTFTYVRDEFLSRKNVLT
                     SQILELVKETLFSPAVVDNGFDPALFEIEKKQLLASLAADMDDSFYFAHKELDKLFFH
                     DERLQLEYSDLRNRILAETPQSSYSCFQEFLANDRIDFFFLGDFNEVEIQNVLESFGF
                     KGRKGDVKVQYCQPYSNILQEGMVRKNVGQSILELGYHYRSKYGDEQHLPMIVMNGLL
                     GGFAHSKLFTNVRENAGLAYTISSELDLFSGFLRMYAGINRENRNQARKMMNNQLLDL
                     KKGYFTEFELNQTKEMIRWSLLLSQDNQSSLIERAYQNALFGKSSADFKSWIAELEQI
                     DKDAICRVANNVKLQAIYFMEGIE"
     gene            32125..33408
                     /locus_tag="VQ862_000737"
     CDS             32125..33408
                     /locus_tag="VQ862_000737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HET3115113.1"
                     /translation="MTKVVFEEKYYPAVKEKVYRTRLANGLTVALLPKKEFKEVYGSV
                     TVQFGSVDTFVTEVDGYVKQYPGGIAHFLEHKLFEREDSSDLMSAFTSLGADSNAFTS
                     FTKTNYLFSATDYFLENLDLLDELVTSAHFTEASILTEQDIIQQEREMYQDDPDSCLF
                     FSTLANLYPGTPLATDIVGSEESISQINLTNLQENFTKFYKPVNMSLFLVGNFDVERV
                     QDYFESKELKDSDFQEVAREKLFLQPVKPTDSMRMEVSSPKLAIGVRGKREVSEADCY
                     RHHILLKLLFAMMFGWTSDRFQKCYESGKIDASLSLEVEITSRFHFVMLTIDTKEPVA
                     LSHQFRKAIRNFTKDLDITEEHLDIIKREMFGEFFSSMNSLEFIATQYDAFENGETIF
                     DLPKILQEITLEDVLDAGHHLIDDGDIVDFTIFPS"
     gene            33450..34271
                     /locus_tag="VQ862_000738"
     CDS             33450..34271
                     /locus_tag="VQ862_000738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HET3115114.1"
                     /translation="MRKKTIGEVLRLARINQGLSLDELQKKTEIQLDMLEAMEADDFD
                     QLPSPFYTRSFLKKYAWAVELDDQIVLDAYDSGSMITYEEVDVDEDELTGRRRSSKKK
                     KKKTSFLPLFYFILFALSILIFVTYYVWNYIQTQPEEPSLSNYSVVQSTSSTSSVPHS
                     SSSSSSSIESAISVSGEGNHVEIAYKTSKETVKLQLAVSDVTSWVSVSESELEGGVTL
                     SPKKKSAEATVATKSPVTITLGVVKGVDLTVDNQTVDLSKLTAQTGQITVTFTKN"
     gene            34282..34827
                     /gene="pgsA"
                     /locus_tag="VQ862_000739"
     CDS             34282..34827
                     /gene="pgsA"
                     /locus_tag="VQ862_000739"
                     /EC_number="2.7.8.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000712151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-diacylglycerol--glycerol-3-phosphate
                     3-phosphatidyltransferase"
                     /protein_id="HET3115115.1"
                     /translation="MKKEQIPNLLTIGRILFIPIFIFILTIGNSIESHIVAAIIFAVA
                     SITDYLDGYLARKWNVVSNFGKFADPMADKLLVMSAFIMLIELGMAPAWIVAVIICRE
                     LAVTGLRLLLVETGGTILAAAMPGKIKTFSQMFAIIFLLLHWTLLGQVLLYVALFFTI
                     YSGYDYFKGSAYVFKGTFGSK"
     gene            34824..35651
                     /locus_tag="VQ862_000740"
     CDS             34824..35651
                     /locus_tag="VQ862_000740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter ATPase"
                     /protein_id="HET3115116.1"
                     /translation="MKSIIDVKNLSFRYKENQNYYDVKDITFHVKRGEWLSIVGHNGS
                     GKSTTVRLIDGLLEAESGEIVIDGQRLTEENVWNIRRQIGMVFQNPDNQFVGATVEDD
                     VAFGLENQGLSRQEMKKRVEEALALVGMLDFKKREPARLSGGQKQRVAIAGVVALRPA
                     ILILDEATSMLDPEGRRELIGTVKGIRKDYDMTVISITHDLEEVAMSDRVLVMKKGEI
                     ESTSSPRELFSRNDLDQIGLDDPFANQLKKSLSQNGYDLPENYLTESELEDKLWELL"
     gene            35636..36475
                     /locus_tag="VQ862_000741"
     CDS             35636..36475
                     /locus_tag="VQ862_000741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000510406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter ATPase"
                     /protein_id="HET3115117.1"
                     /translation="MGIALENVNFIYQEGTPLASAALSDVSLTIEDGSYTALIGHTGS
                     GKSTILQLLNGLLVPSQGSVRVFDTLITSTSKNKDIRQIRKQVGLVFQFAENQIFEET
                     VLKDVAFGPQNFGVSEEDAVKTAREKLALVGIDESLFDRSPFELSGGQMRRVAIAGIL
                     AMEPSILVLDEPTAGLDPLGRKELMTLFKKLHQSGMTIVLVTHLMDDVAEYANQVYVM
                     EKGRLVKGGKPSDVFQDVVFMEEVQLGVPKITAFCKRLADRGVSFKRLPIKIEEFKES
                     LNG"
     gene            36468..37262
                     /locus_tag="VQ862_000742"
     CDS             36468..37262
                     /locus_tag="VQ862_000742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000377903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HET3115118.1"
                     /translation="MDSMILGRYIPGDSIVHRLDPRSKLLAMMLLILIVFWANNPLTN
                     LILFIATGIFIALSGVSLSFFIQGLKSMFFLIAFTTIFQLFFISNGNVLFEFSFVRIT
                     DYALQQAGIIFCRFVLIIFFSTLLTLTTMPLSLASAVEALLAPLKRVKVPVHEIGLML
                     SMSLRFVPTLMDDTTRIMNAQKARGVDFGEGSIVQKVKAMIPILIPLFATSLKRADSL
                     AIAMEARGYQGGKGRSQYRQLKWTLKDTLTILVILVLGCCLFFLKS"
     gene            37321..38139
                     /gene="mreC"
                     /locus_tag="VQ862_000743"
     CDS             37321..38139
                     /gene="mreC"
                     /locus_tag="VQ862_000743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001078980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreC"
                     /protein_id="HET3115119.1"
                     /translation="MNRFKKSKYVIIVFVTVLLVSALLATTYSSTIVTKLGDGISLVD
                     RVVQKPFQWFDSVKSDLAHLTRTYNENESLKKQLYQLEVKSNEVESLKTENEQLRQLL
                     DMKSKLQATKTLAADVIMRSPVSWKQELTLDAGRSKGASENMLAIANGGLIGSVSKVE
                     ENSTIVNLLTNTENADKISVKIQHGSTTIYGIIIGYDKENDVLKISQLNSNSDISAGD
                     KVTTGGLGNFNVADIPVGEVVATTHSTDYLTREVTVKLSADTHNVDVIELVGNS"
     gene            38139..38633
                     /gene="mreD"
                     /locus_tag="VQ862_000744"
     CDS             38139..38633
                     /gene="mreD"
                     /locus_tag="VQ862_000744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001249461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreD"
                     /protein_id="HET3115120.1"
                     /translation="MRQLKRVGVFLLLPFFVLIDAHISQLLGSFFPHVHLASHFLFLF
                     LLFETIEVSEYLYLVYCFVIGLVYDVYFFHLIGITTLLFILLGAFLHKLNSVILLNRW
                     TRMLAMIVLTFLFEMGSYLLAFMVGLTVDSMSIFIVYSLVPTMILNFLWITVFQFIFE
                     KYYL"
     gene            38727..39905
                     /locus_tag="VQ862_000745"
     CDS             38727..39905
                     /locus_tag="VQ862_000745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000727004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HET3115121.1"
                     /translation="MKKKILASLLLSTVMVSQVAVLTTAHAETTDDKIAAQDNKISNL
                     TAQQQEAQKQVDQIQEQVSAIQAEQSNLQAENDRLQAESKKLEGEITELSKNIVSRNQ
                     SLEKQARSAQTNGAVTSYINTIVNSKSITEAISRVAAMSEIVSANNKMLEQQKADKKA
                     ISEKQVANNDAINTVIANQQKLADDAQALTTKQAELKAAELSLAAEKATAEGEKASLL
                     EQKAAAEAEARAAAVAEAAYKEKRASQQQSVLASANTNLTAQVQAVSESAAAPVRAKV
                     RPTYSTNASSYPIGECTWGVKTLAPWAGDYWGNGAQWATSAAAAGFRTGSTPQVGAIA
                     CWNDGGYGHVAVVTAVESTTRIQVSESNYAGNRTIGNHRGWFNPTTTSEGFVTYIYAD
                     "
     gene            40129..40908
                     /gene="rpsB"
                     /locus_tag="VQ862_000746"
     CDS             40129..40908
                     /gene="rpsB"
                     /locus_tag="VQ862_000746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000268478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S2"
                     /protein_id="HET3115122.1"
                     /translation="MAVISMKQLLEAGVHFGHQTRRWNPKMAKYIFTERNGIHVIDLQ
                     QTVKYADQAYDFMRDAAANDAVVLFVGTKKQAADAVAEEAVRSGQYFINHRWLGGTLT
                     NWGTIQKRIARLKEIKRMEEDGTFEVLPKKEVALLNKQRARLEKFLGGIEDMPRIPDV
                     MYVVDPHKEQIAVKEAKKLGIPVVAMVDTNTDPDDIDVIIPANDDAIRAVKLITAKLA
                     DAIIEGRQGEDAVAVEAEFAASETQADSIEEIVEVVEGDNA"
     gene            40987..42027
                     /locus_tag="VQ862_000747"
     CDS             40987..42027
                     /locus_tag="VQ862_000747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003053075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Ts"
                     /protein_id="HET3115123.1"
                     /translation="MAEITAKLVKELREKSGAGVMDAKKALVETDGDIEKAIELLREK
                     GMAKAAKKADRVAAEGLTGVYVNGNVAAVIEVNAETDFVAKNAQFVELVNTTAKVIAE
                     GKPANNEEALALIMPSGETLEAAYVSATATIGEKISFRRFALIEKTDAQHFGAYQHNG
                     GRIGVISVVEGGDEALAKQLSMHIAAMKPTVLSYKELDEQFVKDELAQLNHVIDQDNE
                     SRAMVNKPALPHLKYGSKAQLTDDVIAQAEADIKAELAAEGKPEKIWDKIIPGKMDRF
                     MLDNTKVDQAYTLLAQVYIMDDSKTVEAYLESVNASVVEFARFEVGEGIEKAANDFEA
                     EVAATMAAALNN"
     gene            42273..42560
                     /gene="tnpB"
                     /locus_tag="VQ862_000748"
     CDS             42273..42560
                     /gene="tnpB"
                     /locus_tag="VQ862_000748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HET3115124.1"
                     /translation="MMIQLSDLGQVHIVCGKTDMRQGIDSLAYVVKTHFELDSFSGQV
                     FLFCGGRKDRFKVLYWDGQGFWLLYKRFENGKLTWLSTEKDVKALAPEQVD"
     gene            complement(42751..>42876)
                     /locus_tag="VQ862_000749"
     CDS             complement(42751..>42876)
                     /locus_tag="VQ862_000749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
                     /protein_id="HET3115125.1"
                     /translation="RKRGFKNKAFRTLEDVIQGLEKEVIKSIVNRRRTRMLFESR"
BASE COUNT        13431 a         7401 c         7898 g        14146 t
ORIGIN      
        1 ttatttttcg tcattcattt ttgactttac ttcatcatag gatagtgcat gagattcctc
       61 ttctactgct tcaggcatct ttcctgtttc gtaaagagct ttaatttgtg tactatccaa
      121 tgtttcgtat ttcaataatg cttctgcaat taacttgtga atttcacgat ttgactgaat
      181 aatttcagca gctttatttc gtgcctcatt taataatgaa cgaacctctt catcaatttc
      241 ataagctgtt tgttctgaaa ttgatttttg aggactctgt gcaccaaaca tagcatggtt
      301 tccttcatat tgtactgggc caagtttttc actcataccg tactctgtaa ccattgcacg
      361 cgccatttgt gtcgcttgtt caaagtcgtt tgaagctcct gtagtttgga cattaaagat
      421 aatttcttca gctacacgtc cacccattaa gccagccaat tgctctttca tatcttcttt
      481 agatagaagc atttgatcct ctttaggaag tgcaatcatg tatccgcctg cacggccgcg
      541 tggtacaatt gtaaccttat ggacaacgcg agcattcgac aagactagac caacaatggt
      601 atgtcctgcc tcatggtaag caaccaattc tcgttctttt tgtgaaactg tcttatcttt
      661 cttagaaggt ccagcaataa ctctatcttc tgcttcatca atatctgaag catcaattat
      721 cgatttattg cgacgagcag caactaaagc tgcttcattc aagacattct ctaaatcagc
      781 accaacaaag cctggagttt gttgagccac taatttcaaa tcaacatctt ctgctaaagg
      841 cttgttctta gcgtgaactt tcaagattgc ttcacgacct ttaacatcag gacgaccaac
      901 caatactttt ctatcaaaac gtcctggacg caaaagggca ggatcaagta catctgaacg
      961 gtttgtcgca gcgatgacga taatcccttc atttccctca aaaccatcca tctcaatcaa
     1021 aagttggttc aaggtttgtt cacgttcgtc attacctccg ccgagaccga ctccacgttg
     1081 acgtccaaca gcatcaattt catcgataaa gatgatagct ggtgctgctt ttttggcatc
     1141 ctcaaaaaga gagcgaacac gactagctcc aactccgaca aacatttcta caaagtcaga
     1201 acctgagata ctaaagaatg gaacacctgc ttctccagcg actgccttag caagcaaagt
     1261 tttacctgtc cccggaggtc cctccaaaag aacacctgct ggaatacggg ctccaagttt
     1321 tgtgaatcgt tttggatctt ttaagaactc aacaacttca actagttctt gtttttcttc
     1381 ctcagctcca gcaacatctg aaaatcttac tttaatatct tctttatttg ctgctttagc
     1441 cttactacgt ccaaaactca ttggattacg gccattgcct cctcccatat ttcccatcat
     1501 agagaatagg aagaagaata gaattccaaa tggcacaatg gatacgagta gattaatcca
     1561 tataccactt gaactttcat gcttaacagt tacttctgct ttatggtcag tagcaagttt
     1621 ttgcaattct gatacggtag tatctgcagg aagaatagtg ctggtaaatt tctctacctt
     1681 agtaacagat ggcgtgaaaa actgaatacc tgtttcttct ttacttgttt taggattttt
     1741 atagacacca gaaacttcga taacactacc atttggttgg taagttaatt cttttacatt
     1801 accatcggta atttcttgta ccaactcagt atagttgatt tgctgacttc ctcctgagtt
     1861 attcccagaa tagaaatact ggaatcctgt cacaaggaaa aagataaata ataaccatag
     1921 aaaaggattt ttaattaaac cattattttg ttttttcatt aaagattatt ctttctaatt
     1981 tgaatacact tcctctttca atactccaat ataaggaaga ttacgataat tttctttgta
     2041 gtctaaacca taacctacta caaactcatt tgggatagta aagcaggtat agtctgcctc
     2101 aatttctaca acacgtcctt ctggtttatc caacaaggtt gcaattttaa cagaagctgc
     2161 ttctcttgct ttaaacatat ctcgcaaatt cttcaaagtt tgacctgtat caatgatatc
     2221 ttctacaaat agaacatgtc ttcctttgat atcttgagtc acatcttgtt taatattgat
     2281 aacaccacta cttgctgttc caccatggta gctagaaacc atcatgaagt ccatttcaat
     2341 atgtgtatca atatgtttga ccaattcagc cataaaagga atagatcctt ttaaaatccc
     2401 aactaagatt ggattttttc ctgcatagtc tttagttaat tgagcaccta gttttttagc
     2461 tgcttctgta atttcatcgt gtgaaacgag gactttttta atatcgtttt ctaacatttt
     2521 ttacctatct attttttcta tataaagtac agtgttcatt atatcatttt tcgttttttt
     2581 actcaaatta ttggtcgcaa ttcccaaaat tgagacaatt tcaccaaatt gctcaataat
     2641 aagagcagag tttctctttt ccatagggat tttcaaatca ataaataaac gtctgagttt
     2701 ttttctatgc ccattttgaa tcaaaacatc tcctgttttt cgatgacgaa tgtgtatgga
     2761 tgtttcacgt gaaacaggta tttgttgaat tgattcacct tctaatggaa gtccaaagga
     2821 aaataaatat ccttgataag ctacctgatt ttgatagtgt aacacaagtt catcttcctc
     2881 ttcatcagcc tgcggactga ttttacaaat ctgaaactgt tggtactctt ttatcaattc
     2941 atagccattt ttaatcggat gacgatactg gcttttagat tttaaaatct gctgaacttc
     3001 agcaaactga gcttttgtaa gattcaaatc tggaaaacga ttcagataag tttgaagtaa
     3061 aactctttgt gtagactcag agtaagaaaa taactgctgt aaatcttcca cattaatatt
     3121 gttagataat tcagctattg ccaaatcata atctaaaatt tcattgccaa tgcctaagat
     3181 tgcatcccta aatcgaggat tttctttttc caattctggt aagtaagagt ttcgaatacg
     3241 atttcgaaaa taatgattct cctgatttga tgtatcttca aagtgaaaaa ttgatggaaa
     3301 gtcttttttc tgaaaatgca agaagggacg aatgatttct atctctccga ctacttgctt
     3361 ctccttaatt cctgatagat agcgcaagcg agttcctcga atcaagcgca tcaaaatcgt
     3421 ttccacctga tcatcagcat ggtgggcagt gactaaagct gtcgcacctg tctttttcat
     3481 gacctcttga aaaaaatcat aacgaaaatt tcgtgcacgc gcttctgaaa attctcctga
     3541 aaaattgctg atataaatag gaagctctgc ttcagcagcc aacttcctta attccttttc
     3601 ttcccaatct gattcaattc tctgcttatg attcacatga gctagaatca attcaatctc
     3661 taactctttt tgataagtag acaatacctt aaatagaaac atggaatcta atccaccaga
     3721 aagagctaga accgccttag catgcttttt gaaatatccc ttcttgagaa aatgatttaa
     3781 aaaatctggt tccctcattt tagaacctca taaacatcct tggctatctt agaaatcgta
     3841 tcataatcag aattcttagt gaaaatagaa agaataaatg gagaatctgc atagacaaca
     3901 cccgtatcat gcttaaattc atccgcatct ccaattttat gagctacttt aacagaaaca
     3961 cctttggcaa ttcgctgact atcaaaatct gttttagtca aagactctaa cacaaatcca
     4021 ttttgattat aaatagcttc cataaacttc ccggccatct tagaagaaat caatttttct
     4081 tttggatccc aatcatctcc cataatggca gacatcttgg atttgaatgt ggcatcagat
     4141 tggtttgaaa tgtaatatcc caatagatta tgagctacat tatcagattc ttttgatact
     4201 ttcgtaatta aatcctttaa agaatattct ttattatctt cttttttagg aagactacca
     4261 cttccctctg gtttataaga acctggaaaa tcattgactg cagatacgta ttttacagtc
     4321 gtatctaact gataaagacc ctcatttatt ttttcttgcg tataatagag ataagagagt
     4381 ttcaaaacgc tggctgcata catcttttca tcttgattga taccagcttc ttttccagta
     4441 gtcagttgct taacataaat agagaaagaa tctttctgat atttttcaga taacatttct
     4501 tgaactttac tcatccgatt atcttcttca gaagttgatt ctttagctac ccatccagcc
     4561 tgatcaatat gtagaaattc tcttccttct acaaacatgg tcttgtcgat tgatacttgc
     4621 gaataagctg ataaggatga tttcacttct tttaaatcat aaggactatt gtacagttta
     4681 aagtcagatt ctaaccatgc tttttttatt gttggagtta cctctgattg atcatataaa
     4741 aatcgtttgt ccgcagctat aaattgatga tttgatagct taaatactgg aattccttgt
     4801 ttatttaagc gccactcggt tatttgaaaa cttgttttgg gagtcaattt cccagattcc
     4861 actactaaat cttcattcgc ataaacagga acctctccat aaaccatggg agaacttaat
     4921 ttttctctaa aataaatacc aaagtcagat tgtgaaaggt aataaatttc tttcgaagta
     4981 tagacgactt ctttttctgt gctaacgact tttgaaatgg tcaaaaaact tggtagcaac
     5041 aaaataatta agaatttacg cattcttcct ttccttttct tcttgtaaac gcaataattg
     5101 atttttatca gccaattctt ccagcttttc atctgacaaa ctcaaaaatt gctctattac
     5161 gtctaataaa ttttccattt tatcaccttt gaagcaagtc aggaatcgta taaacttttt
     5221 ccctcgactt agaataatag tacttcgctc gtgtatattt ggcagcataa tcttcatctt
     5281 tcaacttggt agcaaatgct gtctccttat ccttttcatc actcaaagtt tgatactgag
     5341 tttgcaagtc tgctaattgc tgacgtcttt ggagtaattg ctgataactc tgcgctaaat
     5401 taaaagttgg caagataaat aatagcataa tcaaaatcaa tacccctccc ataaaacgat
     5461 tccgtttttg tcgttctttc atcaggtagc gacgacgttg gtattcattt tgaataaaag
     5521 aattattcaa ttgtacaata tttttagaca ttttcttcta cccgtgtttc actgataatt
     5581 tcatacattc ctgctgcatc ttcttttttt gtactatctt tcatctctag tacttttaca
     5641 agcagcaact tattgccaaa gcgaatttca acttggtcat taactttcaa gtccgttgaa
     5701 cttttggcca agattccatt aaccttgatt ctacctttat ctgctacttc ctttgcgact
     5761 gtacgacgct tgataattcg cgatactttt aaatatttat ctaatctcat ccttattacc
     5821 tcaatttatt attgtaccat ttttatctat tttatagaag aaaaatatca aatggaattt
     5881 tcttccttag actcttttat ctctaataaa ctttctccaa aaatcagcag accttctaaa
     5941 atttcataat ctttcttatt ttggacatca aatacaagct ccattaatcc cttattctca
     6001 gcgatgcctg cttttaagtt cgttacggat aaagctttaa aataatcttg agctaaaaac
     6061 aatcgttgag tgactttttc aaattgaatt gtaattttat tatcttttct ttccacacgt
     6121 tgaacaaaga ccttgtccaa gtatgattta accaaaccaa tctctaaaag ataggctact
     6181 acatctgggt attctccaaa acggtctatc aactcctctt gtaactcttc ataattgaca
     6241 cggttgtcaa tttgacgaat tttcttgtaa atttcaatct tatgtcgttg atcagaaata
     6301 taagtatcag gaagataggc atcaatttgc aaaatcaact cagcattccc tttggttctt
     6361 gtgttagcgt tagcattacc gtttcgttta gcaatagctt cctctaataa ctgcgaatac
     6421 aattcaaaac caacagaatc aatgaaacca gactgggatt ttcctaaaag atttcctgct
     6481 ccacgaatcg aaagatctcg cattgcaatc ttaaagccag agcccaattc tgtaaatcct
     6541 ttaatcgctt ctaatctctt ttcagagact tcactgattg atttttctgg acgatacatg
     6601 agataagcat aagcaatacg attactacga ccgactcttc ctcttaactg atataaggtt
     6661 gacaagccca tatggtccgc attttcaata aataaagtat tagcatttgg aatgtccacc
     6721 cctgtctcaa taatagtagt cgtcaccaag atatcgtatt gtccctcaat aaagtctaat
     6781 agagtatttt ccaactggac ttcactcatt cgaccatgaa catatccaat cgaagcctct
     6841 ggaatcaact cctgtaattc tgaaaccttc tgaacaattg tatcaacttt gttgtaaaga
     6901 taataaactt gacctccacg ctccatttca cgcaagacag catcacgaat gacactatca
     6961 ttcttttcca aaacataggt ctgaacagga tagcgattag tcggcggagt ttcaataaca
     7021 gacaaatctc tgattcccag catagacata tggagggtac gagggattgg cgtagcggtc
     7081 aaggttagga catccacttg tttcttcagt tctttcaaag tttccttatg cttgacacca
     7141 aatcgctgtt cctcatcaat aatcatcaag cccaaatcag caaacacaac atcttttgac
     7201 aaaacacgat gtgttccaat caaaatatcg acttgaccgt ttttcaattt ttcaagtgtt
     7261 gcagtctgct cttttttact tctaaagcga ctcaacacat caacattaac tgcaaaattt
     7321 tggaatcgtt ccttaaaatt cgtatagtgc tgttgcgcta aaaccgtcgt cggaactaga
     7381 atgacaacct gtttgtgatc attgactgct ttaaaggctg cacgcatagc aacttcagtc
     7441 tttccaaaac caacatcccc aactaaaagt ctatccattg gctgagaagc ctgcatatcc
     7501 ctcttgattt cctcaatact acgaagttgg tcatccgttt caacataagg gaaagcatca
     7561 tcaaaggcat cttgatcatc atcatcagct gagaaagcaa aacccttcaa ctgactacgt
     7621 tcagagtaga gtttgattaa atcatcagct atatcctcta cctggttctt aaccttttgc
     7681 ttggcctttt taaaatgacc gtcatttaat ttattgagtt ttggagcttt accatcactt
     7741 gaaatatatt tggacagtag atgaatctgt tccacgggaa tagaaatttg atcaccattt
     7801 tggtattgga cactgacata atcacgatga attcccttga tttcaatggt ttcaattcct
     7861 agatattgac caatcccatg gatatgatgg acaacatagt cccctttttc aagttcattg
     7921 taatctttta atctctctgc atttgaaaca tgttgtcttc gaaaacgacg ctttaatttc
     7981 ttttgaaaaa tctcatgttc agttatcaat aaaatctttt catctacaaa atgaaaacca
     8041 tgtctgagat taccttctat taagtttaca gattctttac agatacttgt cttatctcta
     8101 gaatccaatt taatctgata ttcctctaac atatcctcca atgttttact tcccattgaa
     8161 ttgctagact gcagaataat ggtgtaatcc atttttttat atcgttcaat ttcttctttt
     8221 agaaaagaaa actgattgaa aaattcctgc ataggatatt gattgaattg ataaattttg
     8281 tcaaatttga gatttcctaa acccttttga agattagaga aaaaggtcac tggactttgt
     8341 tttttataga tttgttcaat atcagaaaaa tactgcatat cagaaaatgc tttactattc
     8401 tgtaattctt ctgtaaagta ctgcgctaat tctctttcaa agacttcata ctgattcatc
     8461 aatttttgat aatcatcaaa gaatattgga gtatcttttt caatataatc aaagacagtc
     8521 catgtcttat catagcacaa agataaaaac ttccgagaat ctgcatgact ttgcttttga
     8581 tgaaaacttg aaagaatttc ttctaggtat gatttcaaaa taggtgataa agtttttgaa
     8641 atttgttttt ctaaagctga ctgtcctcgt tgataatcct tttctctcaa aagcatatca
     8701 ctagctggaa agatagtgag ttctgtctta ttttctttcg ataattgtgt ttctacttca
     8761 aatgacctga taccatcaat ttcatcacca aaaaactcaa ttcgacaagg ttctaactgg
     8821 gatatttcaa aaatatctaa aatatctcct cgaagactaa attcaccctg agtttgtact
     8881 tgagtaactt ttcgatagcc attttccttt aactgatgga taaacgcgtg ttgagcatat
     8941 tcttcaccaa ctgagatttt tacaatacta tctttgaatg cattgggaga cggtaaaatc
     9001 aatcgacttg ctgcgatatt acaaactaaa atccctttct tagatgaatc agtcaaaaaa
     9061 cgcaaggctt caacccgtga aataattttt tcctgtgaag acatcaaaaa ctccaccata
     9121 ggagcatcat ctaccaaaaa tggatagacg agttcctcac ccaagataga aataagatca
     9181 ctaacaagtc cttctgcttc tccataagtt gacgtcaata acacaatcct atcttctttt
     9241 tctaaactgc ttgcaattgc aagagcctta gtagatgttg ataaaccaag tattagttgt
     9301 cttttcttat ctgttaaatt ttgatgccat tttttaatct gatcattttc tgagaataaa
     9361 tctaataagg tcaccattta tccgttatac ctctgcattg ttttctcaaa atttttctct
     9421 tgtaaatagt agtttacaga atcgtcaact ttgtcaacag actgtaaaat accgatataa
     9481 tcatccctgt caaacttact caaaacatga tgaacaactg acataccatt tttaggtctt
     9541 ccaattccaa tcttaacacg gttaaagacc tgagttccta tatgttgaat aatagacttg
     9601 ataccattat gaccacctgc tgagcctttt gctcttaaac gaattttccc aacttccatg
     9661 tcaagatcat cgtaaatgat aagtaaatcg tcaatatcca aaccatagta agttaataaa
     9721 gcatgaactg cttttccact ttcattcata aaggtcgttg gtttaaccag ataaattttt
     9781 tctccattta ggaaaaagga tgctaggtca gcttgaaata tcttatcgtg tgtaaaagtg
     9841 acattctgtt tcttcgctag ttgatcaatc aacataaaac caacattgtg ttttgtttca
     9901 aaatatttat cccctggatt tcccaagcct acaagtaatt tggtcattta tttttccttt
     9961 caaaagccaa aagggttgga atttttttcc aacctaattg acaccattta ttaattttta
    10021 gacattaaag cggaattcca tgatatcgcc atcttgaacg atatattctt ttccttcttc
    10081 acgcaagcgt ccagcttctt ttacggcctt ttcagatccg tatttcacta gatcttcata
    10141 tgacatggtt actgcacgaa taaagccttt ttcaaagtct gagtggataa taccagctgc
    10201 ttgaggagcc ttcataccac gtttgaaagt ccaagcgcga acttcttttt caccagctgt
    10261 gaagtaagtt cccaatccaa gcaagtggta agctgcacgc gtcaacttat ctacacctga
    10321 ttctgtcaaa ccaatggctt caagaaactc ttttttatct tcatcatcca attcagaaat
    10381 ttcttcctca gcacgcgcag aaataacgac tacttcagca ttttctgtcg ctgcaaattc
    10441 acgaatttgt ttgacatagt cgatagagtc aggttccgaa accacatcct catccacatt
    10501 agctacataa agaactggtt tagtcgtcaa aaggaaaaga cctttgacaa ccttttgttc
    10561 ctcatctgta aattcaatgg tacgagctga tttcccatct tctaggactg gtttaatctt
    10621 ttgaagaaca ttgaattctg ctactgattc tttatctttt tgcgtacgtg ccatcttttc
    10681 tacacgcgca tatcgtttgt tcactgattc taagtcagca agaatcaatt ccagattaat
    10741 ggtatcaata tctgcaagcg gatctacaaa ggcgtcttca cgtccttgct cgcgcatcac
    10801 attttcatca tcaaaagcac gaactacgtg aacaatcgca tctacttcac gaatattggc
    10861 caagaattta ttccctagcc cctctccttt tgaagctcct tttacaatcc ctgcaatatc
    10921 tgtaaattca aatgttgtgg gaactgtctt tttaggagtt atcatttcag ttagtttttg
    10981 tagacgttca tctggaactt ccaccattcc aacatttgga tcaatcgtcg caaatgggta
    11041 gtttgctgcc tctgctcctg cttttgtaat tgcattaaat agtgttgatt taccaacgtt
    11101 tggcaaacca acgatacctg ctgtcaaagc catatttctc attctccgtt ttcatttcaa
    11161 tccctaatat tataacacaa aaagggataa agtgctaacc ctctaactaa gggttctcag
    11221 tcaataattt tattcatttt tcgctcaaaa tcatatcgcc ccatcatgac aacatgctca
    11281 caattactgc attttatttt gatatctgct cctacacgtg taatttccca acgattagcc
    11341 tttttaccag tcgacttgat tgtacaagcg tgtggttttt tcatctcaac aaaatttcca
    11401 acttgataca tactactctc cttttctttt tcgattatat cataaaagag gcgagccagg
    11461 ctcaacctct ttcacttaat ttgtacgaac tggtgtaatg agctgcatga agtcttcgtc
    11521 agtatctgct ggcacaagag taaatggacg aacagctgag ataaagctaa tggtcacctt
    11581 ttcgctattt aaagctttaa gagaatcaat caagtaagtt gggttgaaac taatggtcaa
    11641 atcttcacca gtaacctgat cagtatcgat ttcttcgttt actttaccaa cttctggaga
    11701 gtgaacatgg gcgctaacaa ccccatcctt aatttcaagt ttcacagtac cattttgagt
    11761 cgcacttgat aaaagacggg cacgctccat tgactggcgt aagtttacca cattaaaagt
    11821 aatagtagtg ttaaagtctg ttggaatcaa gcgatctgta tcaggatagt ttccttctag
    11881 gagacgagta tagaagctaa tattttcgct tctaaagagg atttggttat tggcaaagaa
    11941 aatctctaca gtttcgatat catctgtaaa taccgctgaa aattcgcgta gagaacggct
    12001 aggaattacg acatcaaaat catcactatt tttttcaaga gtcaattttt tctggcttag
    12061 gcgatgagag tctgttgcaa ctgtttttaa ctctttgtgt tgactcaata cgaagtggac
    12121 acctgttaaa atcggacgac tctcttgtgt acttgcagca aaggctgttt cattaataat
    12181 tttcttgagt aattttgttt caagtattaa aggagtgctt gctgaaattt cttggattcg
    12241 tggatattgt tcgctatctt ttccttttag ggtaatttct gatttgccac tggttaaaac
    12301 aatttgattt tgttcaattt ctttaaaatc aagagttaca tcaggtaaac tagatactac
    12361 attgataaag aaagaagctt caagaaggat cgaacctaaa gaagtaatca acaaaccagc
    12421 atcttcattt ttttgagaaa taaaattttc aattgagatt tgaccatttg aaccaattaa
    12481 agtaatacct tcattggtca cgtcaatttt tactgttgat aaaataggaa tggcattttt
    12541 agaactaata gctctcttag tagtatttaa tgcttgtaga aataaatttt tattaattga
    12601 aaaatgaatc atggattctc ctttatttat ttttagtatt agaaagataa tagtaataat
    12661 agagtctgtg aaatctgtgg aaaacagcct ttaaacaagt cctatcaagt tttttagctt
    12721 gtttaaaaaa tgtggataaa aaagataaaa aactaaaagt tatccacaaa ttatttgatt
    12781 ttctttttga ttgattcaat ttctaaacgt aaattatcgt cttgatcaat caaagatttt
    12841 attttggcat gggcatgaat gactgtggta tgatcttttc ccccaaattc cttcccaatt
    12901 tttggaagac tattatctgt tagttctcta gataaataca tggctacttg acgggccaaa
    12961 acaatatttt gaaggcgtct acttcccttc atttctttga tactaacacc ataaaagtta
    13021 ccaacttcag tttggatttt atcaattggg atgacgagca tttggctaac atcttgtttg
    13081 cgggctctaa tggcttctgc agcaatatca atagtgatat ccttgatttt ttttactctg
    13141 gcaattaaag tgatgtcgtt gatggctccc tcaagatctc gaacatttga atcaaattgc
    13201 ccagctaggt attctagagt atcactttgg aaattgtagc ctaaatgttc cgttttactt
    13261 tgtaaaatgg caatacgtgt ttcaaagtca gggggtgtga tagtttgtgt caatccccaa
    13321 ctaaaacgcg tgacaagcct ctcctcgagc ccttctagat gttttggact acgatcactc
    13381 gttaggacaa tctgtttttg cttgtcatga agggcgttaa aggtattgaa aaattcttcc
    13441 tgagttgcga ctttttttcc gctgagtgac tggatatcat cgattaacaa aagatcaaga
    13501 ctacgatagg tctttttaaa cttttccatt tccccaagtc ttaggtgatc aagaaagtca
    13561 ttaataaagc tttcggcagg gatatattta acacgcgcat taggaatatt ttttagaatt
    13621 tcatttccaa tagcgtttaa taagtgagtc ttaccaaggc ctggtcctcc atagataaaa
    13681 agagggttat aggtcagagc caaatcttca gagacagcta aagcggctga tacagcccaa
    13741 acatttccat ccccttgaat aaagttatca aaggtatact tttcttttaa tcccgtatct
    13801 gaataaggaa tagatactaa ctttggacta tagtcataaa gagttaaatt tgtagcttct
    13861 tcaacttgtg agctagtcgt atcttgaggt ttggtgaaaa tatagtgggg agttatttca
    13921 gcgtcataaa tttcaaaacc agctactaca ataatatctt ttagttgttt ttcccagacc
    13981 atttccattt cagagcgagg tagaaatata gtggcaacat tttcctctac cttgataagt
    14041 tcagcttgaa tagcatagaa atcatacatg gatcgagtca gtctttcttg tgcaaattct
    14101 aatatacgat tccaaaattg tttttctttc aatcctttct cctcctttac tatttaaaag
    14161 tttaatacta gagatatttt accatagata gcaagaattt tccacaagct gtgaaaaata
    14221 atccacaatg ttaccaaact ttatccacag gttggggata aaagaagaaa ttattgattt
    14281 attaagcttt ttatcgaaaa acatagtgga taaccttgtg agataaaaaa ataaaagaac
    14341 agccttattt caggctgttg ataattctac tatattcttc ttgatttgaa aaagaaataa
    14401 tgatttttcc actgtctttt ttagatagtt taatttctac atctaatccg agtagttttc
    14461 ttaactgttt ttcttcattt tgtatgaaat gattagtttt ttgctgtttc ttttgttttt
    14521 tctctgtcag aagagcttct aatttcctta cagaaatatc ttcttctata atccgttgaa
    14581 agaaatagtc ttgttgttcc ttatttaacc caactaggga acgcgcatgg gcttgtgata
    14641 gtttgccatt ttctacttct gaaagaatct gttctggcaa ggaaagtaaa cgaatggagt
    14701 tgctgatata tggacgagac ttgcccatct tatctgcaat ttcagcatgg gtgaatcctt
    14761 tctctacgag agattcatag gcgcgtgctt cttctattgg gtttaaattt tctctctgta
    14821 aattttcaat aatggactgg accatcatct cttggtctga aatctgttta acaacagctg
    14881 ggatagaccg tagaccagct aaaagtgaag cccgatagcg tctctctcct gcaaggattt
    14941 cataaccaat aacaggagat tgacgaacaa taatcggttg aatgacccca ttttctttga
    15001 tagactgtgc tagttcatct agtttttctc tatcaaattc ttttcggggt tgatagggat
    15061 ttttttgtat atctgtgata gaaatcattt caaatttttc catgattcta cactaacaca
    15121 tcttttctct tatgtaaagc tttctttaca tagatgtcaa ttaagattct aaatcacctg
    15181 aactcttgtt aagtttgata gaggtagttt cttctttccc gttacgatag taggttatct
    15241 taatggtgtc tccgatagaa tggttgtaaa gagcactttg taagtctgtt gatgaagcaa
    15301 tctctttgtc atctactttt gtaattacat cgtatttttc aaggtgacca ttggcaggca
    15361 tattactttg taccgaacga acaattacac cagatgtaac attacttgga atattgagtc
    15421 ttctgatgtc gcttgtactc acattagata aattaaccat ctggattccc aaagctggac
    15481 gcgtcacttt tccgtttttt tctaactgtt caataatatt gatagcatca tttgcaggaa
    15541 ttgcgaaacc aagaccttct acagatgttc ctccatttgt agcaatttta cttgaggtaa
    15601 ttccgataac ctgcccttga atattgatca gtgggccgcc agagttacct gggttaatag
    15661 cagtatcagt ttggatggct tttgtagaaa tagcttgtcc atcttccgat tttaaggata
    15721 catttctatt gagactggat acgatacctt gagtgacagt atttgcatat tcagaaccta
    15781 acgggctacc gatggcaata gcagtttctc ctacagttaa cttactagaa tcaccaaact
    15841 cagctactgt tgtcactttt tctgaagaga ttttgacgac agcaatatca gagaaagtgt
    15901 cagctccgac aatttttcca ggtactttag tcccatctga caatcgaata tctactttgc
    15961 tggcgccatt tataacgtga ttgttggtga cgatgtaagc ttctttatca ttctttttat
    16021 aaataactcc agatccttca ctagagattc gctgagaatc tgtgtcagta tcatcattgc
    16081 caaatacgct attttgtctg tttgccgaat aagtaataac agaaacaaca gcatctttta
    16141 ctttgttaac agcctgtgtt gttgaatttt cgttcttata ggcagtttgt gtaatagtac
    16201 tattgttgtt agagttgttt acactacttt tttgagttag ttgagttatt gaaaaactac
    16261 ccaaggctcc actaaaaaag ctaatgacga taacgactaa taattgaaac cattttttgt
    16321 aaaatgtttt tagatgtttc atatttgcct ccatatgttt gaattactga aagtataaac
    16381 tgactagctt aattataact taaacacaaa agttttacac aaactgtgga taactctttt
    16441 gaaattgtga ttttcttaat tgaaatctat tttttatttt gtgaataaga tgtgaaaaaa
    16501 tagagaatat gttagaatag agtcatgaaa attaaagttg taacagttgg gaaactgaaa
    16561 gaaaagtatt taaaagatgg tatcgcagag tattcaaaac gaatttctag atttgctaag
    16621 tttgaaatga ttgagttatc agatgaaaaa acaccagata aggccagtga atcagaaaat
    16681 caaaagattt tagaaataga aggtcagaga attttatcaa aaattgctga ccgtgatttc
    16741 gttattgtgt tagccattga agggaaaact ttcttctcag aagaatttag taagcagtta
    16801 gaagaaactt ctataaaagg attttctact cttactttta ttattggggg aagtttagga
    16861 ttgtcatcat ctgtaaaaaa tagagccaat ctttctgtca gttttggtcg cctaacctta
    16921 ccccatcagt taatgagact agttcttgtt gaacaaatct atcgcgcttt tacgattcag
    16981 cagggattcc cctaccataa atagaaaatt gacttttaat tgaatttttg gtagaataat
    17041 tgtattaggt ctcatagctc agctggatag agcattcgcc ttctaagcga acggtcgcag
    17101 gttcgaatcc tgctgggatc aatataatag caaagctggg aattttcccg gcttttttct
    17161 taaaaaagta cactttggga gaaaaaaatg acagttgaga gaattttatc taaaacgaaa
    17221 ttccattttg tataatggtt tttgtaagtt agcttacaag aaaaaacatt ttaggagatt
    17281 ttattatgaa aaacacagtt aaattggaac agtttgtagc tttgaaggaa aaagacttac
    17341 aaaagattaa aggtggggag atgaggttgt caaaattctt ccgtgatttt attttacaaa
    17401 gaaaaaagta atgaaataag gggaaagagt aatggattta tttggatttg ggacggttat
    17461 tgttcatttt ttaattatta gtcacagtta ccattttatt tgtaaaggtc aaataaatag
    17521 aaaagaatta ttcgtttttg gtgcttatac attactaaca gaaatagtat ttgattttcc
    17581 cttatatatt ctatatttag atgggttagg gattgaaaga tttttatttc ctttgggatt
    17641 atattcctat tttcgatgga tgaaacagta tgagagggat agaggactat tcctaagttt
    17701 actactatct cttttatatg agagcactca taactttctg tccgtaactt tctcctctat
    17761 aacaggagat aattttgttt tacaatatca tttcccattc tttttcgttg tgacggtgtt
    17821 aacctatttt gttacattaa aaatcattta ctatttccat ttggaactag cctattttga
    17881 tgaggactac ctttatcctt tcttgaaaaa agtatttttt gctttactat tgctacatat
    17941 tgtatctttc gtttcagata tggtaagtac gattaaacat ttgaatagtt ttggaagtat
    18001 tttgtcatct attgtcttta tctctctcct tttgaccttc tttgcaatga attctcataa
    18061 agttcaaatg gagaaagaga ttgctttgaa gcagaagaaa tttgaacaga aacatttaca
    18121 gaattacaca gatgaaattg ttggtctgta taatgaaatc cgtggttttc gacatgatta
    18181 tgctggaatg cttgtcagca tgcagatggc aattgacagt ggtaatttac aggaaattga
    18241 cagaatttac aatgaagttt tagtcaaagc aaatcataaa ttgcgttcag ataagtacac
    18301 ttactttgat ttgaacaaca tagaagactc agctttacga agtttggttg ctcagtcaat
    18361 tgtctatgct cgaaataatg gtgtagagtt tacactggaa gtaaaagata cgattaccaa
    18421 gcttccaatt gaactattgg atttggttcg tatcatgagc gttttattga ataatgctgt
    18481 cgaaggatcg gctgatagct ataaaaagca gatggaagta gcagttatta agatggaaac
    18541 tgaaacagtt attgtgattc agaattcatg taaaatgacg atgactcctt caggagatct
    18601 atttgcctta ggattctcca ctaagggaag aaatcgcgga gtcggattaa ataatgtgaa
    18661 agaactacta gataagtaca acaatattat tttagaaaca gagatggaag gcagtacatt
    18721 tagacaaatc attagattta agagggaatt tgaatgaaag ttttaatttt agaagatgtt
    18781 attgaacatc aagtgagact agagagaata ttggatgaaa tttcgaaaga atcgaatatt
    18841 ccaatatcat acaagacaac gggaaaagtc cgtgaatttg aagaatacat tgaaaatgat
    18901 gaagtaaatc agctttattt cctagatatc gatattcatg gaattgagaa aaagggattt
    18961 gaagtggctc agctcattcg tcattacaat ccttacgcta ttatcgtctt tatcactagt
    19021 cgatcagagt ttgcgactct aacatataaa taccaggtat cagccctaga ttttgttgat
    19081 aaggatatca atgatgagat gtttaagaag agaattgagc aaaatatctt ctacacgaag
    19141 agtatgttac ttgaaaatga agatgttgta gattatttcg actacaatta caagggaaat
    19201 gatttaaaaa ttccttacca tgatattttg tatattgaaa caacaggggt atctcataaa
    19261 ttgcgcatta ttggtaagaa ttttgcaaaa gagttttatg gtaccatgac agatattcag
    19321 gaaaaggaca aacatactca gcgattttat tctcctcaca agtcattttt ggtaaatata
    19381 ggcaatatca gagaaattga tcgaaaaaac ttagaaattg ttttctatga agaccatcgt
    19441 tgtcctattt caagattaaa aattagaaaa ttaaaagata ttttagagaa aaaatctcaa
    19501 aagtgattga caattagcaa gaaattgata taatggttat atctgctaca gatagaaggt
    19561 ccgttggtca aggggttaag acaccgcctt ttcacggcgg taacacgggt tcgaatcccg
    19621 tacggactat tttatccgcc atagctcagt tggtagtagc gcatgactgt taatcatgat
    19681 gtcgtaggtt cgagtcctac tggcggagta tagataaaag ggaacacagc tgtgttcctc
    19741 tttttgtatc aatttgtatc accaagcatt ttcataagga agtctgttat ttcttgagaa
    19801 ctttcttttt ttccatgtgc aatccaagtt tggcagacac caaaaagtgc atgagttaga
    19861 tagatgctac tatattctaa ttcggtggta tttagattca gttgcataaa tcgcttttgt
    19921 aaatctgtac taagcatgat atgaagttta tttcgtaaga aattttggat ttctttagtc
    19981 ccattttcag aaagaagggc agccagaagt ggttctgact ctagatattc aaaaacttct
    20041 aaaatagcgt ctcttttgtg atgagcatgt ttttgaaaaa tatattcaaa tgtatggaat
    20101 agcttgcttt gatagtgctc aatcatatca tacttatcct tatagtgagt atagaagctg
    20161 gaacgactaa ttccggcttt ttctactaat ttgacagtag aaattttatc aaatggctgt
    20221 tccatcagta attgtaccat agcattttca atagttcgct ttgtttttaa gcgtttgtta
    20281 ctttcttgca tatttcctcc ttgtaaacaa attagactat atgtctaaaa atagattttt
    20341 tatcttgtaa tttagatttt ttaatgtata atctattata tcaaaatttt agacaatatg
    20401 tttaaaaaag gagaaactaa gtttaaagaa tggaaagcaa tttaaaaaaa accaaccttt
    20461 attattgtca tgatcgggat ttctcttatt ccagatctgt acaatatcat atttttgtca
    20521 tcaatgtggg atccatatgg gcaattgtct gacttacctg tggcagttgt aaataatgat
    20581 aaagaggctt cctataatgg taatactatg gcaataggaa aagacacggt gtccaattta
    20641 aaagaaaata aaaccttgga ttttcatttt gtagatgaag aggaaggaaa gaagggattg
    20701 gaagatggcg attactatat ggtagtgact ttaccaagtg atttatctga aaaaacaact
    20761 acattatcca atattcaatc gacagcagct tatcaatcat tgacaagtga gcaacaaact
    20821 gagataagtg attctgtatc tcaaaattca actgatagta ttcaatcggc tcagtcaatt
    20881 gtagctttag tacaagattt acagggaagt ttagaaaact tacaaaatca atcttctaat
    20941 ctttcgactt taaaaaatca atctaatcaa gtatcaccta ttacttctac ttctttgata
    21001 ggattgtcaa gtggattaac agagatacaa ggagatgtta ctagcaaatt agttcctgcc
    21061 agtcagtcga ttgcatcagg tgtaaacgca tatactacag gtgttgataa agtttctcag
    21121 ggcgcaagtc aactaagtga aaaaaatgcc accttgacag gtagtttgga taaactagtt
    21181 tcaggctcaa acaccttgac acaaaaatct tctagattga cagcaggagt tggttaatta
    21241 caatcaggat ctgggcaatt agcagacaaa tccagtcagt tactttcagg tgcttctcca
    21301 ttagagaata gagctaataa attggcagat ggatctagga aactagcaga aggtggaaca
    21361 aagttaactt ctggattgga agatttacag acaggacttg cttctttagg acaaggacta
    21421 ggtaatgcta gtgatcaact caaatcagta tcaacagaat ctaaaaatgc agagattttg
    21481 tcaaatccac tcaatctttc aaaaacagac aatgatcaag ttcctgtaaa tggaatcgca
    21541 atagctcctt atatgatatc agttgctctt ttttttgcag caatatcaac aaatatgata
    21601 tttgcgaaat tgccttcagg acgtcatcca gagagccgtt gggcttggtt gaaatcttga
    21661 gctgaaataa atggtattat agctgttttg gcaggaattt tggtatatgg aggagttcag
    21721 cttattggtt taactgctaa tcatgagatg agaatattta ttctcatcat cctaacaagt
    21781 ttagtattca tgtctatggt gaccacttta gcaacgtgga atagccgtat aggagctttt
    21841 ttctcactta ttttgctttt actacagtta gcatcaagtg caggtactta tccacttgct
    21901 ttgacaaatg atttctttag atctattaat ccctggttac caatgagcta ttcagtttcg
    21961 ggattacgac aaacaatctc tatcaacaag tcattttcct agctgtcata ctagctctat
    22021 ttactggttt aggtatgcta gcctatcaac ataagaaaat ggaagaagat taaaaaaatc
    22081 gaccgattaa ctggtcgatt ttttatgcct tagatgactt tcgtctgtga ttatagattc
    22141 caaatagtaa gagagaagta aaggaacaga ttgctccagt aataaaacca ttgggaatga
    22201 aggaaagtgt aatagttcct ttccccttgg gaatgtcaac tttcataaat ccagtttgag
    22261 cttgtttaat ttctattttc ttaccatctt ggtaggcaga ccaacctttg tcataaggaa
    22321 tggtgaagaa aatagatgta tcttgttgga catcatatgt agcaaaaacc ttgtttttag
    22381 aagttgatac tgtgacaggt tgttctttaa ttttttgaat tgcctcggtg aaagttttgg
    22441 tatctaaacg atagaaggta ggagattcaa atgatacttg tgaatttcca gggaaactaa
    22501 cattgatatt gaaagttttt ttctctttag tatatcctag attaaagaag gagaagacat
    22561 tatcagttgt aaaagtcttt ttttcaccat ttacaaggat gtcaaccttc ttttgtttat
    22621 cgttagaaaa gtgaaggttt atgaaagaga gataaacttg gctgttttct ggaacttcaa
    22681 tttgatactg gattgctgca tcttcatttg aagaacttgt gacactaatc aaatcattag
    22741 tattttctat tttttctgtt ttttcataag gtattggaga aaaataatca aaattgacgt
    22801 tagcaagttg atttaaaaat gaggcctgat tatccaaggt atgttcattg aacttgacat
    22861 cattgtaaac agattgacta gcaactgcaa tcggaagaga gtattgattt tcatataggg
    22921 taagattatc tttttgatag atatctttaa agccatactt atcaatagga ctgtctgaga
    22981 tattgtactg gataccaaat aaactatcag ccaaaatact attatttgca tatcggagat
    23041 tgagattagt cccagaggat ttaaaaccaa gtttatctaa agtagagctt gatgaacgat
    23101 ttcgaacaga tgaaaattga gagattccat tgtagttgaa tttcatactg tcatttcctg
    23161 tctgagtttg tagtttttca gtacgagtaa attgatttcc aatatatgtt gagaaagatt
    23221 ccatagctag gatatctcga ctataagcac ttcgagaagc aaatccccat tccttagcaa
    23281 ttccgtccat ttgagatgaa gcatttaaac tcatttcaac cagtataaat aaagagatta
    23341 gaatggcaaa tagattcaca gatataaact ttttgataac tgcaaggagt aaaagagaat
    23401 agacaaccaa aaattcaaga gtaagcagaa tattcaaatc tgttaaaaaa gaataatgcg
    23461 attttagata gatggtagct aaaaatcctg ctactacaag aaaaagcgaa actaaaaaat
    23521 tccagacttt aagttctttc agacgcttta agacttctgc tgctgtgtaa attaacaagg
    23581 tagagaaaat ccaagcatag cgatgtaaaa acatgtttgg agtatgcatg ccttgccaaa
    23641 ataagtcaag agcttctatg taaaagcttg caattagaaa tgcaaagaat attacatata
    23701 tgagtttcac gtgaaactta atagatttca gcgtaaaaaa taaaatggtc aaaataaagg
    23761 gaaatagtcc aacaaaaatc attgggatgg ccccatactt tgttgtgtca aaggaaccaa
    23821 tgaattgctt agcaaagaga tcaagatacc agctactttc agtttgaaac tttgtaactt
    23881 cagtcaattt ttccccatgt gtctgtaaat caaatagagt gggaagagtc ataatcaaac
    23941 tagccatacc agctaaaaag gagataacta tgaaatcaag aacagatgat tttcgagtct
    24001 taaagtccca cgaaatttga cagagatacc agaaaataag aaacaatact gtcatatatc
    24061 caaaataata attttgaata aataagattg acagacttgt aaagtacaat aggagtttct
    24121 tttcagttat cagtagatgt aaaccagtta taattaaagg aatcaagata aaaacatcta
    24181 gccaggtttt tatctctaat tgactgacag tgaaactcat cagagcatag gaagtagata
    24241 aggctagttt taaagtctga gggatagatt gaaacaattt attcaaacta aaaaaggttg
    24301 acagaccaat caatccaaat tttaagagag tggtcagata gacagcatct ggcatgttcg
    24361 ttagatcaaa aaagtaaact agaggcgcga gaaaactacc caagtaataa ctagataggg
    24421 catagaagtt tagccctaga ccacttgtaa aggtgtaaaa cagactacta tttccatgta
    24481 ggatatttcg taaggctaca tcaaaaataa cgtattgatg aaagccatct cctaatagag
    24541 gagagttgtc gctattccag tagatacctt gagatagata tactccagac ataatcacta
    24601 caggaatgat gagagaaata aaataggttc gatatgtttt taaaaatgat ttcatgttac
    24661 ctcgtagaat gatagaaaac tcagttggtt aacccaactg agttttgaag ttttatttag
    24721 tctttccaaa gttctttaac ttttgcttgt acttctgcat tttctaggaa ttcatcgtag
    24781 gtttcatcga tacggtcaat gacgccattt ttagataaga caatgatatg gttagccaaa
    24841 gtttgaataa attcgtggtc atggctagca aagatgattg attctttaaa gtttttcaat
    24901 ccatcattca agcttgagat agattccaag tccaagtgat ttgttggatc atcaagtaca
    24961 aggacatttg attttaagag catgagtttt gaaagcatga cacgaacttt ttctccccct
    25021 gacaagacat ttacaggttt gttaacttca tctccagaga agagcatacg gccgaggaag
    25081 ccacgtagga aagtattgtc atcttcttct ttacttgcga attgacgcaa ccagtcaaga
    25141 attgattctc ctcctgcaaa atcagctgag ttatcttttg gtaggtaaga ttgactagtt
    25201 gtaactcccc acttgacagt tccttcatag tcaatatctc ccatgattgc acgaattaat
    25261 gcagtcgttt gaatatcatt ttgtccaata agtgctgtct tatcatctgg acgcaagatg
    25321 aaactaatat tatccaagat agtttcacca tcaatcttta cagttagatt ttctactgtc
    25381 aagagatcat taccaatctc acgttccgct ttaaagttga taaatggata tttacgacta
    25441 gatggtacaa tctcttctag ctcaatctta tcaagcattt tcttacgtga tgttgcctgc
    25501 cttgacttag aagcattggc agagaaacga gcaacgaatt cttgcaattg tttaattttt
    25561 tcttctgctt tagcattacg gtctgctagc aatttagcag caagctcaga agattccttc
    25621 cagaagtcgt agtttccgac atagagtttg atttttccaa agtcaaggtc ggccatgtga
    25681 gtacaaactt tgtttaagaa gtgacggtcg tgggatacta cgataactgt gttatcaaag
    25741 tcaatcaaga agtcttctaa ccaagtaatc gattggatat ccaaaccgtt agtaggctcg
    25801 tccaagagaa gaacatctgg tttaccaaaa agtgctttgg cgaggagaac ctttactttt
    25861 tcaccgttgg ccaattcgct catgttttgg tagtgtaatt cttctggaat gtttaggttt
    25921 tgaagtagtt gagaggcttc actctctgct tcccaacctc caagttcggc aaactctcct
    25981 tcgagttcgg cagcacgaac cccgtcctcg tctgagaaat cttccttcat gtagatagca
    26041 tctttctctt tcatgatgct ataaagtttt tcatttccca tgataacgac atcaatggca
    26101 cgttcatctt cgtagtcaaa gtgattttga cgaagaacag agagacgttc atctggacca
    26161 agagagatgt gaccagtagt aggttcgata tctccagcta aaatttttaa aaaggttgat
    26221 tttccggcac cattagcacc gattaatccg taagtatttc cttctgtaaa tttgatattg
    26281 acatcatcaa aaagtttgcg atcactaaaa cgtagtgaaa catcagatac tgtaagcaat
    26341 atttttctcc tatatgtgta atatatttat tctactagaa aatacagaaa tattcaaatt
    26401 tttatttgtc aattttgtgt aaattatatt tacagtatcc tttacacaaa tctgtaaaaa
    26461 gcaaggctga tttattttga taaattacgg ttatttcatt aaaaaaatgc tataattgaa
    26521 aggactatat cgaaggagaa caaaatgact aaacccatta ttttaacagg agaccgtcca
    26581 acaggaaaat tgcatattgg acattatgtt ggaagtctca aaaatcgagt attattacag
    26641 gaagaggata agtatgatat gtttgtgttc ttggctgacc aacaagcctt gacagatcat
    26701 gccaaagatc ctcaaaccat tgtagagtct atcggaaatg tggctttgga ttatcttgca
    26761 gttggattgg atccaaataa gtcaactatt tttattcaaa gccagattcc agagttggct
    26821 gagttgtcta tgtattatat gaatctagtt tcgttagcac gtttggagcg aaatccaaca
    26881 gtcaagacag agatttctca gaaaggattt ggagaaagca ttccgacagg attcttggtc
    26941 tatccaatcg ctcaagcagc tgatatcaca gctttcaagg ctaattatgt tcctgttggg
    27001 acagatcaga aaccaatgat tgagcaaact cgtgaaattg ttcgttcttt taacaatgca
    27061 tataactgtg atgtcttggt agagccggaa ggtatttatc cagaaaatga gagagcaggg
    27121 cgtttgcctg gtttagatgg aaatgctaaa atgtctaaat cactaaataa tggtatttat
    27181 ttagctgatg atgcggatac tttgcgtaaa aaagtaatga gtatgtatac agatccagat
    27241 catatccgcg ttgaggatcc aggtaagatt gagggaaata tggttttcca ttatctagat
    27301 gtttttggtc gtccagaaga tgctcaagaa attgctgata tgaaagaacg ttatcaacga
    27361 ggtggtcttg gtgatgtgaa gaccaagcgt tatctacttg aaatattaga acgtgaactg
    27421 ggtcctattc gtgagcgccg tattgaattt gctaaggata tgggagaagt ttataatatg
    27481 attcaaaaag gtagtgaaag agcgcgtgaa gttgcgggtc aaaccctatc tgaggtaaaa
    27541 ggggcaatgg gacttcatta ctttaactaa gtttatttta caagaaacta tcatttctat
    27601 ctcgaagaaa agatagtttt ttatttaccc ctgtaacatt tgacaaattt ttatagaatg
    27661 gtatgataga tacaatataa aaagagtcaa gctcaaaaag aaagaaaaga ggaaacttcg
    27721 aatgtctaat tgggacacta aatttttgaa aaaaggtttt acctttgatg atgtattgct
    27781 tattccagct gaaagtcatg tgttgcctaa cgatgcagat ttaacaacta aattggcaga
    27841 taatttgact ttaaatatcc caattattac cgctgccatg gacacagtta cagagagtca
    27901 aatggccatt gctattgctc gtgcaggtgg tctcggagtt atccataaaa acatgtcaat
    27961 tgctcaacaa gcagacgagg ttcgtaaggt aaaacgttct gaaaatggag ttattattga
    28021 tccgttcttc ttgacgcctg aacatacaat tgctgaagca gatgagctta tgggtcgtta
    28081 ccgcatcagt ggtgttccag ttgttgaaac acttgaaaat cgtaaattgg ttggtatttt
    28141 gacaaaccga gatcttcgtt ttatttcaga ttataatcaa ccaatttcaa accatatgac
    28201 tagtgaaaat cttgttactg ctcctgtggg tacggatctt gcaacggctg agagtattct
    28261 tcaagagcat cgtattgaaa aacttccgtt ggtcgatgaa gaaggcagtc tttctggttt
    28321 gatcactatc aaagatattg aaaaagttat tgagtttcca aatgcggcta aagatgaatt
    28381 tggtcgtctt ctagttgcag gtgcagtagg tgttacttca gatacatttg aacgtgcaga
    28441 ggctcttttt gaggcaggag cggatgcgat tgttattgat actgcacatg gtcattctgc
    28501 aggtgtcttg cgtaaaattg ccgagattcg tgctcatttc ccagatcgga ctttgattgc
    28561 tggaaatatt gctactgctg aaggtgcacg tgccctttat gaagcgggtg tagacgttgt
    28621 taaggttggt attggaccag gttctatctg tactactcgt gtgattgctg gtgttggtgt
    28681 tccgcaagta acagctatct acgatgctgc agctgttgcg cgcgaatatg gtaaaacgat
    28741 tattgctgac ggtgggatca agtattctgg agatattgta aaagcacttg ctgcaggtgg
    28801 aaatgctgtt atgcttggat ctatgtttgc tggaactgat gaagctccag gcgaaactga
    28861 aatcttccaa ggacgtaaat tcaagactta ccgtggtatg ggatcaattg ctgctatgaa
    28921 gaaaggttca agcgaccgtt atttccaagg ttctgtcaat gaagcaaaca agctcgttcc
    28981 agaaggaatt gaaggtcgtg ttgcttataa aggagcggca gctgatattg ttttccaaat
    29041 gattggtggt attcgctctg gtatgggtta ctgtggtgca gctaacctta aagaactaca
    29101 cgataatgct caatttattg aaatgtctgg tgctggtttg aaagaaagcc atcctcatga
    29161 tgtgcaaatt actaatgagg caccaaatta ttctatgtaa aaaacaatga aaagaactcc
    29221 agtgaaaaca ggagttcttt tacaatgttg tcaatttcca tttacagaag ctttaccatc
    29281 ctgaatagtg aagatactta gattttctgg cagattttga agatggtcta agcttgttgt
    29341 tgtgataaag gtttggattg attgagaaat cgtttctaat aattttaact gtctagtgtt
    29401 gtcaagttca ctcatcacat cgtcaagcag taatatagga gattctgtgg taatgctttc
    29461 cattaattcg atttctgcta attttatcga gaggacgaga ctacgatgtt gaccttggct
    29521 tccgaaacta gcatccatcc catttatata aaaagaaatg tcatctcgat gaggaccgac
    29581 accagtattc tttttaaata aatctctgga tctacttttt tctaaagcaa ttttgaaaga
    29641 ttcggataag ttttgtttgt cagttatatt gacagaagat tgataggata ttgacaactc
    29701 ttcgatctga ttagagagtt caaaatgttt cttacgccca aatgattcta gtttttttat
    29761 gaaatctaag cggtgattca ttacacgaca tccataatca actagctgat catctaacac
    29821 agaaaggaat gtttcatcta ttttttgagc tgattttagg taagtgtttc tttgctttag
    29881 gatgtggtta taattggtta agtcagataa atagattggc ttaatttgcc caagttccat
    29941 atcaatgaat tttcgtcgaa tcgaaggtgc tcctttaatt agttgtaaat cttcaggagc
    30001 aaataagaca acattcatgt gtcctacata atctgaaagg cgtgcctgtt ttaagtgatt
    30061 aacttttgtt acacggcctt tttgtgttag ttcgatttct aggggaatgg atccagtttt
    30121 tttctgaacg agacctgaaa gatgaagttg ttcctcatca aaatgaatga gatttttatc
    30181 tgttcgagtt cgatgactac gcgttaaggc taaaaaatag atagcctcta acatgtttgt
    30241 ttttccttgt gcattacgtc ccaaaaagac attcaattta ggattaaagt ctattttcgt
    30301 ttctttgtaa ttacgaaaag tcttgagaga tagatgttgt agccacatga ttatctacca
    30361 gggaatcgtg gagcttgttg gcttttaggt gatgaagcag gtttcgattt gtctttttta
    30421 actcccttat tcatcttttt gacaagttta gcgatccgtt ctttttcaac tttatcagct
    30481 tggtattcat cttgttcttc agaagtaggt tgtgtcaaca agatgtcaat gttcatgtca
    30541 gggatgtcaa ctttatcgcc aatacgaagt ttttttccac gacgactctc taattcccta
    30601 ttaaagtaaa cagaatgttc agagagaaat gatttaatag ctcctccgct atgtgtaatt
    30661 ccaagttctt tgagtagtgc ttggagggta ataaattctt caaataattt gtattccata
    30721 attcacctca atctttggta ttataccata ttttcctaaa aatagtgaga gagacagcga
    30781 gaaatgtaag cgatttttat ttcaaaagtg ttacagggaa caagaaaatt tcaggttttc
    30841 gtgatataat agaagtctgt atataaggag gtaaatcatg gagttagtgc atggaatttc
    30901 aacacatttt atccaatcaa aaaagtttaa aacaaacaaa attaccgtgc gttttaccgc
    30961 tccattatcc cttgatacga ttgcaggtca catgttgagt gcaagtatgc tagagactgc
    31021 taatcagatg taccccactt ctcaagattt gaggagacac ttggccagtc tatacggtac
    31081 agatatgtca accaattgtt tcagaagagg gcaaagccac attatagaat tgacatttac
    31141 ctatgttcgt gatgagtttt taagtaggaa aaacgtgcta acctctcaga ttttggaact
    31201 tgtaaaagaa actctttttt cacccgcagt agttgataat gggtttgatc cggccttatt
    31261 tgaaattgag aaaaaacaat tgctagcaag tttagcagct gatatggatg attcttttta
    31321 ttttgcacat aaagaattgg ataaattgtt ttttcatgat gaacgtcttc aattggaata
    31381 tagtgattta cgaaatcgta ttttagctga aactccacaa agttcttatt cttgtttcca
    31441 agaattttta gccaatgatc gaatagattt ctttttccta ggtgatttta atgaggttga
    31501 aattcaaaat gtattagaat catttggctt taaaggtcga aaaggagatg tgaaggttca
    31561 gtattgtcaa ccttattcta atatccttca ggaaggtatg gttcggaaaa atgtgggaca
    31621 atccattttg gaattaggtt atcattaccg ttctaaatat ggtgatgagc aacatttacc
    31681 catgattgta atgaatggtt tacttggtgg atttgctcac tctaagctct ttacaaatgt
    31741 ccgtgaaaat gctggattag cttataccat ttcaagtgag cttgatttat ttagtggatt
    31801 cttgaggatg tatgctggta tcaatcgaga aaatcgtaac caggctcgta aaatgatgaa
    31861 taatcaactg cttgatttaa aaaaaggtta ttttacagag tttgagttaa atcagaccaa
    31921 ggaaatgatt cgttggtcgt tgttactttc tcaagataat caatcttcat tgattgaacg
    31981 tgcttatcaa aatgccttat ttggaaaatc ttcagcagac tttaaaagtt ggattgcaga
    32041 gcttgaacaa attgacaaag atgctatttg tagagtagct aataatgtga aactacaagc
    32101 gatttacttt atggaaggaa tagaatgaca aaggttgttt ttgaagaaaa atactatcca
    32161 gctgtaaaag aaaaggttta tcgaactcgt ttggccaacg gattgacagt tgctcttttg
    32221 cctaaaaagg aatttaaaga ggtttacggg agtgtcactg tacagtttgg ttcggtagat
    32281 acgtttgtca cagaagttga cggatatgta aaacaatatc ctggaggaat tgctcatttt
    32341 cttgaacata aattatttga gagagaagat tctagtgatt tgatgtcggc ttttacgagt
    32401 ctaggtgcag atagtaatgc ctttacaagc tttacaaaaa caaactatct tttttcagca
    32461 acggattatt ttttagaaaa tttagattta cttgatgaat tggtaacatc agcacacttt
    32521 actgaagctt ccattctgac agagcaggat attattcagc aagaacgaga aatgtaccaa
    32581 gatgatccag attcgtgttt attcttttca actttagcga atttgtatcc tggtacacct
    32641 ttagcaactg atatagttgg aagtgaggag tccatttccc aaatcaatct aactaatttg
    32701 caagaaaatt ttacaaagtt ttacaaacct gtaaacatgt ctctgttttt agttggtaat
    32761 tttgatgtgg agcgagtaca ggactatttt gaaagcaaag aactgaaaga ttcagatttt
    32821 caggaagtag caagagaaaa gttgttttta cagcctgtaa agccaacaga tagtatgaga
    32881 atggaagtat cttctcccaa actagcgatt ggagttagag gtaagcgaga agtttctgaa
    32941 gcggattgct atcgacatca tattttatta aaattattgt ttgcaatgat gtttggttgg
    33001 acttcggatc gttttcaaaa atgttatgaa tcaggtaaaa ttgatgcgtc cttatctctg
    33061 gaagttgaaa taacaagtcg ctttcatttt gtcatgttga caatagatac gaaagagcca
    33121 gttgctttgt ctcatcaatt taggaaggct attcgtaatt ttacaaagga tttagatatt
    33181 acagaggaac atttagatat tatcaaaaga gagatgtttg gcgaattttt cagtagcatg
    33241 aactctcttg aatttattgc aacgcaatat gatgcttttg aaaatggtga gacaattttt
    33301 gatttgccga aaattttaca ggaaattact ttagaggatg tccttgatgc tggacatcat
    33361 ttaatagatg atggtgacat agttgatttt acaatattcc catcgtagta acctatcata
    33421 atagacacta gaaagaaggg atgacaagta tgagaaaaaa aacaattgga gaggttttac
    33481 gattagctag aatcaatcag ggattgagtt tagatgaatt gcagaaaaag acagaaatcc
    33541 agttagatat gttggaagca atggaagcag acgatttcga tcaacttcca agtccttttt
    33601 acacgcgttc tttcttgaaa aaatatgcat gggctgttga gttagatgac caaattgttt
    33661 tggatgctta tgattctggg agtatgatta cttatgagga agtagatgtt gatgaagatg
    33721 agttgacagg tcgtagacgt tcaagtaaga aaaagaagaa aaaaacatca tttttacctt
    33781 tattttattt tatccttttt gctttatcga ttttaatttt tgtgacttat tatgtttgga
    33841 actatattca aactcaacca gaggagcctt ctctttctaa ttacagtgtg gttcaatcaa
    33901 caagttcaac tagctctgtt ccccactcct caagtagtag ttcttctagt atagaatcag
    33961 ctataagtgt atcaggcgaa ggaaatcatg tagaaatcgc ttataagaca agtaaggaaa
    34021 cagttaaatt gcaattggca gtttcagatg ttacaagttg ggtcagtgtt tcagaaagcg
    34081 aacttgaggg cggtgtaacc ttatcgccaa agaagaaaag tgcagaagca acagttgcaa
    34141 ctaaaagtcc tgtaacaatt acgttaggtg ttgtaaaagg tgttgatttg acagtagata
    34201 atcagactgt tgatttatcg aaattaacag ctcagactgg acaaatcact gtaaccttta
    34261 ctaaaaatta aggaaaaacg aatgaaaaaa gaacaaattc ccaatctctt aacaataggt
    34321 cgaattctct ttatacctat ttttatcttt attttaacga taggaaattc gatagagagt
    34381 catatagttg cagctattat ctttgctgtt gccagtatta ccgactattt agatggatat
    34441 ttagctcgta aatggaatgt ggtcagtaat tttggtaaat ttgcagatcc tatggcggat
    34501 aagttactag ttatgtcggc ttttattatg ttgattgagt taggtatggc tccggcttgg
    34561 attgttgcag tgattatctg tcgtgagtta gctgtgacag gtttaaggct tttattggtt
    34621 gaaactggtg gaacaatttt agcagcagca atgcctggaa aaattaaaac ttttagtcag
    34681 atgtttgcta ttattttctt gctattacat tggactttgc ttggtcaagt tctactttat
    34741 gtagccttat ttttcactat ctactctggc tatgactatt tcaagggtag tgcctatgta
    34801 tttaaaggga catttggttc gaaatgaaat caataattga tgtaaaaaat ctttcttttc
    34861 gctataaaga aaatcagaac tactacgatg tgaaggatat tacgtttcac gtgaaacgtg
    34921 gagaatggct ttcgattgta gggcataatg gtagtggtaa atcaacgacg gttcgattaa
    34981 ttgatggctt actggaagca gaatccggag agattgtaat tgatggccaa cgtttgactg
    35041 aggaaaatgt ttggaatata cgtcgtcaaa tcggtatggt ttttcaaaat ccagacaatc
    35101 aatttgttgg agcgactgtt gaagatgatg ttgcttttgg tttggaaaat cagggacttt
    35161 ctcgtcaaga aatgaaaaag agagtggaag aagctctggc tttagttggc atgttggact
    35221 ttaaaaagag agagccagcg cgtctatcag gtggccaaaa gcaacgtgtg gccattgcag
    35281 gtgttgtagc cctaagacca gctattttaa tcttagatga agcaacgagt atgttggatc
    35341 ctgaggggcg tagagaactt attgggacag taaaaggaat tcgaaaagac tatgatatga
    35401 cggtcatttc tattacccat gatttggaag aagtcgccat gagtgatcgc gtattggtca
    35461 tgaaaaaagg ggaaattgaa tcaactagta gtccaaggga gcttttctct cgaaatgatt
    35521 tagatcaaat tggattagac gatccttttg ctaatcaatt aaaaaaatct ttgagccaga
    35581 atggctatga tttacctgaa aattatttga cagaaagtga gctagaggat aagctatggg
    35641 aattgctcta gaaaatgtga attttatata tcaagaaggt actcccttag cttcagcagc
    35701 tttgtcggat gtttctttga cgattgaaga tggctcttat acagctttaa ttgggcacac
    35761 aggtagtggt aaatcaacta ttttacaact cttaaatggt ttattggtgc caagtcaagg
    35821 gagtgtgagg gtttttgata ccttaatcac ctcgacttct aaaaataaag atattcgtca
    35881 aattagaaaa caggttggct tggtatttca gtttgctgaa aatcagattt ttgaagaaac
    35941 ggttttgaag gacgttgctt ttggaccgca aaattttgga gtttctgaag aagatgctgt
    36001 gaagactgcg cgtgagaaac tggctctggt tggaattgat gaatcacttt ttgatcgtag
    36061 tccgtttgag ctgtcagggg gacaaatgag acgtgttgcc attgcaggca tacttgccat
    36121 ggagccatct atattagtct tagatgagcc aacagctggt ctagatcctc tagggagaaa
    36181 agagttgatg accctgttca aaaaactcca ccagtcaggg atgaccatcg tcttggtaac
    36241 gcatttgatg gatgatgttg ctgaatatgc taatcaagtc tatgtaatgg aaaagggacg
    36301 tttagtaaag gggggcaaac caagtgatgt ctttcaagac gttgttttta tggaagaagt
    36361 tcagttggga gtacctaaaa ttacggcctt ttgtaaacga ttggctgata gaggcgtgtc
    36421 atttaaacga ttaccgatta agatagagga gttcaaggag tcgctaaatg gatagtatga
    36481 ttttggggcg ttatatccca ggggattcga ttgttcaccg attggatcca cgtagcaaat
    36541 tgcttgctat gatgctactg attttgattg tgttttgggc taataacccc ttgacgaatc
    36601 tgattctttt tatagcgaca gggatattta ttgccttgtc aggagtatct ctttcatttt
    36661 ttattcaggg cttgaagtct atgtttttct tgattgcctt cacaactatt tttcaactat
    36721 ttttcatttc taatgggaat gttttatttg agttttcgtt tgtgagaatc acggattatg
    36781 ctttgcaaca agctgggatt attttttgtc gctttgtatt gattattttc ttttcaactt
    36841 tgttaacctt aacaaccatg cctttaagtt tggcatcagc tgtcgaagct ttattagcac
    36901 ctttaaagcg tgtgaaagtt ccagttcatg aaattggatt gatgctgtct atgagtttgc
    36961 gttttgtccc aaccttgatg gatgatacga ctcggattat gaatgcacag aaagctcgtg
    37021 gagtggattt tggagaagga agcatcgttc aaaaagtaaa ggcgatgatt cccattttga
    37081 ttcctctttt tgcgacaagt ttaaaacgtg cagattcctt ggctatcgct atggaagcgc
    37141 gtggctatca gggtggaaaa ggcagaagtc aataccgaca attgaaatgg actctaaagg
    37201 atacgctgac cattcttgtt attctcgtac ttggttgttg tttatttttc ttaaaatctt
    37261 agtagctttc aggaattgat aaaaagttac tgtaacagtt tttgatataa aggtagggat
    37321 atgaaccgtt ttaaaaaatc aaaatatgtc attattgttt ttgtcactgt tctgcttgtg
    37381 tcagctctct tagcgacgac ttattcaagt acaattgtga caaaattagg agatggaatc
    37441 tcattggttg atagagttgt acaaaaacct tttcagtggt ttgattctgt caaatcagat
    37501 ttggctcatt tgacacgaac atataatgaa aatgaaagtt tgaagaaaca gctttaccaa
    37561 ttagaagtta aatcaaatga ggtggaaagt ttaaagacag aaaatgaaca actgcgccaa
    37621 ttgcttgata tgaagtctaa attgcaagcc acaaagactt tagcagcaga tgttattatg
    37681 cgttctccgg tatcttggaa gcaggagttg accttagatg caggtagatc aaaaggtgct
    37741 tctgagaaca tgttagctat tgcaaatggt ggcttgattg ggagtgtttc aaaagtagag
    37801 gagaactcta ctatagtcaa ccttctgaca aatacggaaa atgctgataa gatttctgtt
    37861 aaaattcaac atggctctac tacaatttat ggaattatta ttggctatga caaggaaaat
    37921 gacgttctta aaattagcca attaaatagt aatagcgata ttagtgcggg agataaggtg
    37981 actactggtg gattaggaaa ctttaacgtt gctgatattc ctgttggtga agtggttgcc
    38041 acaacgcata gtacagacta tttgacacga gaagtaactg ttaaattgag tgcagatact
    38101 cataatgtag atgtgataga attagtgggg aattcataat gagacagttg aagcgagttg
    38161 gagtattttt attgcttcct ttctttgttc taattgacgc ccatattagc cagcttctgg
    38221 gctcattttt cccccatgta catttggcta gtcattttct ttttctattt ctcttatttg
    38281 agacgataga agtatcagag tatctctacc tagtctattg ttttgttata ggcttggttt
    38341 atgatgttta ctttttccat ctaataggga ttacaactct cttatttatc ttattgggag
    38401 ccttccttca taaattgaat agtgttattt tgttgaatcg ttggacaaga atgctagcta
    38461 tgattgtgct gacattcctg tttgaaatgg gtagttatct tttggctttt atggtagggt
    38521 tgacagtaga tagcatgtcg atttttatag tctatagctt ggtaccgacg atgattttaa
    38581 attttttatg gattactgtt tttcaattta tttttgaaaa atattatcta taagaacgac
    38641 atataaatgt aacaaaggcg taatatttat taggcctttt tttggtatac tagtattgtc
    38701 tttaaaagaa ggagtatcta cgtaatatga agaaaaaaat cttagcgtca cttttattaa
    38761 gtacagtaat ggtttctcaa gtagctgttt taacaactgc gcatgcagaa acgactgatg
    38821 acaaaattgc tgctcaagat aataaaatta gtaacttaac agcacaacaa caagaagccc
    38881 aaaaacaagt tgaccaaatt caggagcaag tatcagctat tcaagctgag cagtctaact
    38941 tgcaagctga aaatgataga ttacaagcag aatctaagaa actcgagggt gagattacag
    39001 aactttctaa aaacattgtt tctcgtaacc aatcgttgga aaaacaagct cgtagtgctc
    39061 aaacaaatgg agccgtaact agctatatca ataccattgt aaactcaaaa tcaattacag
    39121 aagctatttc acgtgttgct gcaatgagtg aaatcgtatc tgcaaacaac aaaatgttag
    39181 aacaacaaaa ggcagataaa aaagctattt ctgaaaaaca agtagcaaat aatgatgcta
    39241 tcaatactgt aattgctaat caacaaaaat tggctgatga tgctcaagca ttgactacga
    39301 aacaggcaga actaaaagct gctgaattaa gtcttgctgc tgagaaagcg acagctgaag
    39361 gggaaaaagc aagtctatta gagcaaaaag cagcagctga ggcagaggct cgtgcagctg
    39421 cggtagcaga agcagcttat aaagaaaaac gagctagcca acaacaatca gtacttgctt
    39481 cagcaaacac taacttaaca gctcaagtgc aagcagtatc tgaatctgca gcagcacctg
    39541 tccgtgcaaa agttcgtcca acatacagta caaacgcttc aagttatcca attggagaat
    39601 gtacatgggg agtaaaaaca ttggcacctt gggctggaga ctactggggt aatggagcac
    39661 agtgggctac aagtgcagca gcagcaggtt tccgtacagg ttcaacacct caagttggag
    39721 caattgcatg ttggaatgat ggtggatatg gtcacgtagc ggttgttaca gctgttgaat
    39781 caacaacacg tatccaagta tcagaatcaa attatgcagg taatcgtaca attggaaatc
    39841 accgtggatg gttcaatcca acaacaactt ctgaaggttt tgttacatat atttatgcag
    39901 attaatttac agagggactc gaatagagcc ctcttttcag gttttaccgt gacaatccct
    39961 attaaaaatt atatcaaaat agcttgaaaa tattggaaaa gtatggtaga atgaaaattg
    40021 tcgtgtgaac gataatactc attcttgatg aattgtgaag cagttgccct tgggtcgttt
    40081 tgcgagttga agtcaagaag aggaaaaaaa caaaaaggag aaatactcat ggcagtaatt
    40141 tcaatgaaac aacttcttga ggctggtgta cactttggtc accaaactcg tcgctggaat
    40201 cctaagatgg ctaagtacat ctttactgaa cgtaacggaa tccacgttat cgacttgcaa
    40261 caaactgtaa aatacgctga ccaagcatac gacttcatgc gtgatgcagc agctaacgat
    40321 gcagttgtat tgttcgttgg tactaagaaa caagcagctg atgcagttgc tgaagaagca
    40381 gtacgttcag gtcaatactt catcaaccac cgttggttgg gtggaactct tacaaactgg
    40441 ggaacaatcc aaaaacgtat cgctcgtttg aaagaaatta aacgtatgga agaagatgga
    40501 actttcgaag ttcttcctaa gaaagaagtt gcacttctta acaaacaacg tgcgcgtctt
    40561 gaaaaattct tgggcggtat cgaagatatg cctcgtatcc cagatgtgat gtacgtagtt
    40621 gacccacata aagagcaaat cgctgttaaa gaagctaaaa aattgggaat cccagttgta
    40681 gcgatggttg acaccaatac tgatccagat gatatcgatg taatcatccc agctaacgat
    40741 gacgctatcc gtgctgttaa attgatcaca gctaaattgg ctgacgctat tatcgaagga
    40801 cgtcaaggtg aggatgcagt agcagttgaa gcagaatttg cagcttcaga aactcaagca
    40861 gattcaattg aagaaatcgt tgaagttgta gaaggtgaca acgcttaatt tatacaaata
    40921 gtaattacct aggagggcgg ggcttagccc ggctctccta ttttcaaaaa atataggaga
    40981 attaaaatgg cagaaattac agctaaactt gtaaaagagt tgcgtgaaaa atctggtgcc
    41041 ggtgttatgg acgctaaaaa agcgcttgta gaaacagacg gtgacatcga aaaagcgatt
    41101 gaattgcttc gtgaaaaagg tatggctaag gcagctaaga aagctgaccg tgttgctgca
    41161 gaaggtttga ctggtgttta tgttaacggt aatgttgcag cagttattga agtaaacgct
    41221 gaaactgact tcgttgcaaa aaacgctcaa ttcgttgaat tggtaaatac tacagctaaa
    41281 gtcattgctg aaggaaaacc tgctaataat gaagaagctc ttgctttgat aatgccttca
    41341 ggtgaaactc ttgaagctgc atacgtatct gcaacagcaa ctatcggaga gaaaatctca
    41401 ttccgtcgct ttgcattgat tgaaaaaaca gacgcacaac actttggagc ataccaacat
    41461 aacggtggac gtatcggtgt tatttcagtt gttgaaggtg gagacgaagc acttgctaaa
    41521 caattgtcaa tgcacatcgc agcgatgaaa ccaacagttc tttcttacaa agaattggat
    41581 gagcaattcg ttaaagatga gttggcacaa ttgaatcacg ttatcgacca agacaacgaa
    41641 agccgtgcaa tggttaataa accagctctt ccacacttga agtatggatc aaaagctcaa
    41701 ttaactgatg atgttattgc tcaagctgaa gctgacatca aagctgaatt ggctgcagaa
    41761 ggcaaaccag aaaaaatctg ggacaaaatt atcccaggta aaatggatcg cttcatgctt
    41821 gataatacta aagttgacca agcttacaca cttcttgcac aagtttacat catggatgac
    41881 agcaagacag ttgaagcata ccttgaatca gttaacgctt cggtagttga gtttgctcgc
    41941 tttgaagttg gtgaaggtat cgagaaagct gcaaacgact tcgaagctga agttgcagct
    42001 acaatggcag cagccttgaa taactaataa tagaaaggaa gcaatttgct tccttttttg
    42061 tatagggctt atatttttcc tgaaattgtt tttcccccag tctcactcga ttagaataat
    42121 taaaacaaaa agccctataa taagggctaa gtgcatttag gagactatac ttcaaattca
    42181 tagtaagcgc gtcataacaa ggtatctatc ctaattcccc aacttccagt atactagata
    42241 aaaaataatt atcggaggaa aggtattgta ctatgatgat tcaactaagt gatttaggtc
    42301 aagttcacat tgtttgtggc aagacagata tgaggcaggg aatagactca ttagcctatg
    42361 tagttaaaac ccactttgaa ttggattctt tctccggtca agtctttctc ttttgtggtg
    42421 gacgtaaaga ccgctttaaa gtcctttact gggatggtca aggattttgg ctactatata
    42481 aacgctttga gaacggaaaa ctgacttggc taagtacaga aaaggatgtc aaagctctcg
    42541 cacctgaaca agtagactag cttatgaagg gcttttctat cactccaaaa atatagtaga
    42601 ttgaaactag aatagtacac ctctgcttct aaaacattgt tagaaatcga tttgactgtc
    42661 ctgatcgatt tgtcctgttc ttatttcatt ttactataaa tccatcagaa agtcgtgatt
    42721 tctattgaaa tgaggacttt ctttttacac tcatctgctt tcaaaaagca ttctagtccg
    42781 tctccgatta acgatggact ttatcacctc cttctctagt ccttgtatga catcttccaa
    42841 agttcgaaag gctttattct taaatccacg tttacg
//
LOCUS       DAVBOD010000013        39993 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 640-05
            SAMEA1012484-rid20186543.denovo.013, whole genome shotgun sequence.
ACCESSION   DAVBOD010000013 DAVBOD010000000
VERSION     DAVBOD010000013.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012484
            Sequence Read Archive: ERR059358
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 39993)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 39993)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979948.1
            Genome Coverage       :: 595x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:03:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,266
            CDSs (total)                      :: 2,219
            Genes (coding)                    :: 2,091
            CDSs (with protein)               :: 2,091
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 71 of 128
            Pseudo Genes (incomplete)         :: 50 of 128
            Pseudo Genes (internal stop)      :: 33 of 128
            Pseudo Genes (multiple problems)  :: 22 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..39993
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012484-rid20186543.denovo.013"
                     /strain="NIG 640-05"
                     /db_xref="taxon:1313"
     gene            131..412
                     /locus_tag="VQ862_000750"
                     /pseudo
     CDS             131..412
                     /locus_tag="VQ862_000750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611513.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            complement(537..740)
                     /locus_tag="VQ862_000751"
     CDS             complement(537..740)
                     /locus_tag="VQ862_000751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000594204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET3115126.1"
                     /translation="MIKLYSPYAFLSKYLGAILLSFFCYYAKEIGCNNLTLSVWNDNE
                     GALRFYQRQGMKPQETTMEMIID"
     gene            complement(733..1815)
                     /locus_tag="VQ862_000752"
     CDS             complement(733..1815)
                     /locus_tag="VQ862_000752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HET3115127.1"
                     /translation="MSKLQQILTYLESEKLDVAVVSDPVTINYLTGFYSDPHERQMFL
                     FVLADQEPLLFVPALEVERASSTVSFPVVGYVDSENPWQKIKHALPQLDFKRVAVEFD
                     NLILTKYHGLKTVFETAEFDNLTPRIQRMRLIKSADEVQKMMVAGLYADKAVHVGFDN
                     ISLDKTETDIIAQIDFAMKREGYEMSFDTMVLTGDNAANPHGIPAANKVENDALLLFD
                     LGVLVNGYASDMTRTVAVGKPDQFKKDIYNLTLEAQQAALDFIKPGVTAHEVDRAARE
                     VIEKAGYGEYFNHRLGHGIGMDVHEFPSIMEGNDMVIEEGMCFSVEPGIYIPGKVGVR
                     IEDCGVVTKDGFDLFTSTSKDLLYFD"
     gene            complement(1941..2723)
                     /locus_tag="VQ862_000753"
     CDS             complement(1941..2723)
                     /locus_tag="VQ862_000753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glutamine amidotransferase"
                     /protein_id="HET3115128.1"
                     /translation="MVYTSLSSKDGNYPYQLNIAHLYGNLMNTYGDNGNILMLKYVAE
                     KLGAHVTVDIVSLHDDFDENHYDIAFFGGGQDFEQSIIADDLPAKKESIDNYIQNDGV
                     VLAICGGFQLLGQYYVEASGKRIEGLGVMGHYTLNQTNNRFIGDIKIHNEDFDETYYG
                     FENHQGRTFLSDDQKPLGQVVYGNGNNEEKVGEGVHYKNVFGSYFHGPILSRNANLAY
                     RLVTTALKKKYGQDIQLPAYEDILSQEIAEEYSDVKSKADFS"
     gene            complement(2723..4066)
                     /locus_tag="VQ862_000754"
     CDS             complement(2723..4066)
                     /locus_tag="VQ862_000754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011836724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mur ligase family protein"
                     /protein_id="HET3115129.1"
                     /translation="MNLKTTLGLLAGRSSHFVLSRLGRGSTLPGKVALQFDKDILQNL
                     AKNYEIVVVTGTNGKTLTTALTVGILKEVYGQVLTNPSGANMITGIATTFLTAKSSKT
                     GKNIAVLEIDEASLSRICDYIQPSLFVITNIFRDQMDRFGEIYTTYNMILDAIRKVPT
                     ATVLLNGDSPLFYKPTIPNPIEYFGFDLEKGPAQLAHYNTEGILCPDCQGILKYEHNT
                     YANLGAYICEGCGCKRPDLDYRLTKLVELTNNRSRFVIDGQEYGIQIGGLYNIYNALA
                     AVAIARFLGADSQLIKQGFDKSRAVFGRQETFHIGDKKCTLVLIKNPVGATQAIEMIK
                     LAPYPFSLSVLLNANYADGIDTSWIWDADFEQITDMDIPEINAGGVRHSEIARRLRVT
                     GYPAEKITETSNLEQVLKTIENQDCKHAYILATYTAMLEFRELLASRQIVRKEMN"
     gene            complement(4165..5481)
                     /locus_tag="VQ862_000755"
     CDS             complement(4165..5481)
                     /locus_tag="VQ862_000755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000958936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-containing oxidoreductase"
                     /protein_id="HET3115130.1"
                     /translation="MLTYDLIVIGFGKAGKTLAGKLASAGKKVALVERSKAMYGGTCI
                     NIGCIPTKTLLVAAEKDLSFEEVIATKNTITGRLNGKNYTTVAGTGVNIFDAEAHFLS
                     NKVIEIQAGDEKQELTAETIVINTGAVSNVLPIPGLATSKNVFDSTGIQSLDKLPEKL
                     GVLGGGNIGLEFAGLYNKLGSKVTVLDALDTFLPRAEPSIAALAKQYLEEDGIELLQN
                     IHTTEIKNDGDQVLVVTEDETYRFDALLYATGRKPNVEPLQLENTDIELTERGAIKVD
                     KHCQTNVPGVFAVGDVNGGLQFTYISLDDFRVVYSYLAGDGSYTLEDRLNVPNTMFIT
                     PALSQVGLTESQAADLKLPYAVKEIPVAAMPRGHVNGDLRGAFKAVVNTETKEILGAS
                     IFSEGSQEIINIITVAMDNKIPYTYFTKQIFTHPTLAENLNDLFAI"
     gene            5675..6901
                     /locus_tag="VQ862_000756"
     CDS             5675..6901
                     /locus_tag="VQ862_000756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000841575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="OFA family MFS transporter"
                     /protein_id="HET3115131.1"
                     /translation="MKSNRYIIAFAGVILHLMLGSTYAWSVYRNPIIEKTGWDQASVA
                     FAFSLAIFCLGLSAAFMGRLVEKFGPKVMGSLSAFLYAGGNILTGFAIDRQELWLLYL
                     AYGILGGLGLGAGYITPVSTIIKWFPDKRGLATGLAIMGFGFASLLTSPIAQHLIAGV
                     GLVETFYILGASYFIIMLLASQFIKRPNEQELAILSSSGKEKTASLTQGMAANQALKS
                     NRFYMLWIIFFINIACGLGLISAASPMAQEMAGLSTSHAAVMVGVLGIFNGFGRLLWA
                     SLSDYIGRPLTFSILLLVNLFFSLSLWLFTDSVLFVVAMSILMTCYGAGFSLIPAYLS
                     DIFGTKELAALHGYILTAWAMAGLAGPILLAETYKMAHSYTQTLFVFLILYSIALALS
                     YYLGRSIKKESQKPLT"
     gene            7100..8674
                     /locus_tag="VQ862_000757"
     CDS             7100..8674
                     /locus_tag="VQ862_000757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HET3115132.1"
                     /translation="MKFNELNLSADLLAEIEKAGFVEASPIQEQTIPLALEGKDVIGQ
                     AQTGTGKTAAFGLPTLEKIRTEEATIQALVIAPTRELAVQSQEELFRFGRSKGVKVRS
                     VYGGSSIEKQIKALKSGAHIVVGTPGRLLDLIKRKALKLQNIETLILDEADEMLNMGF
                     LEDIEAIISRVPENRQTLLFSATMPDAIKRIGVQFMKAPEHVKIAAKELTTELVDQYY
                     IRVKEQEKFDTMTRLMDVAQPELAIVFGRTKRRVDELTRGLKIRGFRAEGIHGDLDQN
                     KRLRVLRDFKNGNLDVLVATDVAARGLDISGVTHVYNYDIPQDPESYVHRIGRTGRAG
                     KSGQSITFVAPNEMGYLQIIENLTKKRMKGLKPASVEESFQSKKQVALKKIERDFADE
                     TIRANFEKFGKDARKLAAEFTPEELAMYILSLTVQDPDSLPEVEIAREKPLPFKPSGN
                     GFGGKAKGGRGGRRGDDRRERDRRGNGRRDEFKKGSRGNDRFDKEKRYRKDNKKPRNT
                     LSEKQTGFVIRNKGDK"
     gene            8939..9727
                     /gene="codY"
                     /locus_tag="VQ862_000758"
     CDS             8939..9727
                     /gene="codY"
                     /locus_tag="VQ862_000758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-sensing pleiotropic transcriptional
                     regulator CodY"
                     /protein_id="HET3115133.1"
                     /translation="MAHLLEKTRKITSILKRSEEQLQDELPYNAITRQLADIIHCNAC
                     IINSKGRLLGYFMRYKTNTDRVEQFFQTKIFPDDYVQGANMIYETEANLPVEHDMSIF
                     PVESRDDFPDGLTTIAPIHVSGIRLGSLIIWRNDKKFEDEDLVLVEIASTVVGIQLLN
                     FQREEDEKNIRRRTAVTMAVNTLSYSELRAVSAILGELNGNEGKLTASVIADRIGITR
                     SVIVNALRKLESAGIIESRSLGMKGTYLKVLISDIFEEVKKRDY"
     gene            9727..10302
                     /locus_tag="VQ862_000759"
     CDS             9727..10302
                     /locus_tag="VQ862_000759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HET3115134.1"
                     /translation="MTKALISIDYTEDFVADSGKLTAGAPAQAISDAISKVTRLAFER
                     GDYIFFTIDAHEENDCFHPESKLFPPHNLIGTSGRNLYGDLGNFYQEHGSDSRVFWMD
                     KRHYSAFSGTDLDIRLRERRVSTVILTGVLTDICVLHTAIDAYNLGYDIEIVKPAVAS
                     IWPENHQFALGHFKNTLGAKLVDENLNELSE"
     gene            10384..10469
                     /locus_tag="VQ862_000760"
     tRNA            10384..10469
                     /locus_tag="VQ862_000760"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:10418..10420,aa:Leu,seq:aag)
     gene            10752..11882
                     /gene="ugpC"
                     /locus_tag="VQ862_000761"
     CDS             10752..11882
                     /gene="ugpC"
                     /locus_tag="VQ862_000761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003010064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sn-glycerol-3-phosphate ABC transporter
                     ATP-binding protein UgpC"
                     /protein_id="HET3115135.1"
                     /translation="MVELNLKNIYKKYPNSEHYSVEDFNLNIKDKEFIVFVGPSGCGK
                     STTLRMIAGLEDITEGTASIDGVVVNDVAPKDRDIAMVFQNYALYPHMTVYDNMAFGL
                     KLRKYSKEDINKRVQEAAEILGLKEFLERKPADLSGGQRQRVAMGRAIVRDAKVFLMD
                     EPLSNLDAKLRVSMRAEIAKIHRRIGATTIYVTHDQTEAMTLADRIVIMSATKNPAGT
                     GTIGRVEQIGTPQEVYKNPVNKFVAGFIGSPAMNFINVKLVGSEIVSDGFRLKVPEGA
                     LKVLREKGYEGKELIFGIRPEDVNAEPAFLETFPDCVVKATISVSELLGSESHLYCQV
                     GKDEFVAKVDARDYLQTGATVELGFDLNKAHFFDVETEKTIY"
     gene            12383..13141
                     /locus_tag="VQ862_000762"
     CDS             12383..13141
                     /locus_tag="VQ862_000762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001848902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HET3115136.1"
                     /translation="MSEAGHKFLAKLGKKRLRPGGKRATDWLIAEGGFSKEKRILEVA
                     CNRGTTAIELAQRFGCKITAVDMDAQALEVAKKSAGTAGVAHLISFERANAMKLPYQD
                     ASFDIVINEAMLTMQADQAKKKCVMEYLRVLKPGGLLLTHDVLLKEAKESIRQELSQA
                     IHVNVGPLTQDGWEQVMIESGYCDVKALTGEMTLMKLSGMIYDEGLLGTLKICVNACK
                     KENRKQFLTMYKMFAKNKQKLGFIAMASYKSSKR"
     gene            13228..13740
                     /locus_tag="VQ862_000763"
     CDS             13228..13740
                     /locus_tag="VQ862_000763"
                     /EC_number="2.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001049318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine phosphoribosyltransferase"
                     /protein_id="HET3115137.1"
                     /translation="MNLKDYIATIENYPKEGITFRDISPLMADGNAYSYAVREIVQYA
                     TDKKVDMIVGPEARGFIVGCPVAFELGIGFAPVRKPGKLPREVISADYEKEYGVDTLT
                     MHADAIKPGQRVLIVDDLLATGGTVKATIEMIEKLGGVMAGCAFLVELDELNGREKIG
                     DYDYKVLMHY"
     gene            13922..14866
                     /locus_tag="VQ862_000764"
     CDS             13922..14866
                     /locus_tag="VQ862_000764"
                     /EC_number="2.3.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001122710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine O-succinyltransferase"
                     /protein_id="HET3115138.1"
                     /translation="MPIRIDKKLPAVEILRTENIFVMDDQRAAHQDIRPLKILILNLM
                     PQKMVTETQLLRHLANTPLQLDIDFLYMESHRSKTTRSEHMETFYKTFPEVKDEYFDG
                     MIITGAPVEHLPFEEVDYWEEFRQMLEWSKTHVYSTLHICWGAQAGLYLRYGVEKYQM
                     DSKLSGIYPQDTLKEGHLLFRGFDDSYVSPHSRHTEISKEEVLNKTNLEILSEGPQVG
                     VSILASRDLREIYSFGHLEYDRDTLAKEYFRDRDAGFDPHIPENYFKDDDVNQVPCLC
                     WSSSAALFFSNWVNHAVYQETPFDWRKIEDDASAYGYL"
     gene            14875..15552
                     /locus_tag="VQ862_000765"
     CDS             14875..15552
                     /locus_tag="VQ862_000765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain-containing protein"
                     /protein_id="HET3115139.1"
                     /translation="MTYLDAFKSGILVLPSALLLHFKELFPSSDDFLVWQFFYLQNTT
                     GLEEMSPSQIAERIGKEISDVNQSISNLTERGLLQYRTIELNGEIELLFDASLALERL
                     DDLFGAVHSSSDQLTPQNQLKDLVETFQQELGRLLTPFEIEDLTKTLKEDGTSADLIK
                     EALREAVLNGKPNWKYIQAILRNWRHEGIKSVAQIEAKRAEREASNPQLTQVSADFIN
                     AMDLWKD"
     gene            15650..16408
                     /locus_tag="VQ862_000766"
     CDS             15650..16408
                     /locus_tag="VQ862_000766"
                     /EC_number="5.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000087908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triose-phosphate isomerase"
                     /protein_id="HET3115140.1"
                     /translation="MSRKPFIAGNWKMNKNPEEAKAFVEAVASKLPSSDLVEAGIAAP
                     ALDLTTVLAVAKGSNLKVAAQNCYFENAGAFTGETSPQVLKEIGTDYVVIGHSERRDY
                     FHETDEDINKKAKAIFANGMLPIICCGESLETYEAGKAAEFVGAQVSAALAGLTAEQV
                     AASVIAYEPIWAIGTGKSASQDDAQKMCKVVRDVVAADFGQEVADKVRVQYGGSVKPE
                     NVASYMACPDVDGALVGGASLEAESFLALLDFVK"
     gene            16446..17951
                     /gene="lytC"
                     /locus_tag="VQ862_000767"
     CDS             16446..17951
                     /gene="lytC"
                     /locus_tag="VQ862_000767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_078138769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline binding-anchored murein hydrolase LytC"
                     /protein_id="HET3115141.1"
                     /translation="MSVTFFIGEERLKTKIGLASICLLGLATSHVAANETEVAKTSQD
                     TTTASSSSEQNQSSNKTQTSTEVQTNAAAHWDGDYYVKDDGSKAQSEWIFDNYYKAWF
                     YINSDGRYSQNEWHGNYYLKSGGYMAQNEWIYDSNYKSWFYLKSDGAYAHQEWQLIGN
                     KWYYFKKWGYMAKSQWQGSYFLNGQGAMMQNEWLYDPAYSAYFYLKSDGTYANQEWQK
                     VGGKWYYFKKWGYMARNEWQGNYYLTGSGAMATDEVIMDGARYIFAASGELKEKKDLN
                     VGWVHRDGKRYFFNNREEQVGTEHAKKVIDISEHNGRINDWKKVIDENEVDGVIVRLG
                     YSGKEDKELAHNIKELNRLGIPYGVYLYTYAENETDAENDAKQTIELIKKYNMNLSYP
                     IYYDVENWEYVNKSKRAPSDTDTWVKIINKYMDTMKQAGYQNVYVYSYRSLLQTRLKH
                     PDILKHVNWVAAYTNALEWENPYYSGEKGWQYTSSEYMKGIQGRVDVSVWY"
     gene            18448..18966
                     /locus_tag="VQ862_000768"
     CDS             18448..18966
                     /locus_tag="VQ862_000768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA starvation/stationary phase protection
                     protein"
                     /protein_id="HET3115142.1"
                     /translation="MVELKKEAVKDVTSLTKAAPVALAKTKEVLNQAVADLYVAHVAL
                     HQVHWYMHGRGFLVWHPKMDEYMEALDGQLDEISERLITLGGSPFSTLTEFLQNSEIE
                     EEASEYRNVEESLERVLVIYRYLSELFQKGLDVTDEEGDDVTNGIFAGAKTETDKTIW
                     MLAAELGQAPGL"
     gene            19096..19602
                     /locus_tag="VQ862_000769"
     CDS             19096..19602
                     /locus_tag="VQ862_000769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000162460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HET3115143.1"
                     /translation="MTKKIVAIWAQDEEGVIGKENRLPWHLPAELQHFKETTLNHAIL
                     MGRVTFDGMGRRLLPKRETLILTRNPEEKIDGVATFQDVQSVLDWYQAQEKNLYILGG
                     KQIFQAFEPYLDEVIVTHIHARVEGDTYFPEELDLSLFETVSSKFYAKDEKNPYDFTI
                     QYRKRKEL"
     gene            19804..21036
                     /gene="clpX"
                     /locus_tag="VQ862_000770"
     CDS             19804..21036
                     /gene="clpX"
                     /locus_tag="VQ862_000770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002874765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit
                     ClpX"
                     /protein_id="HET3115144.1"
                     /translation="MSTNRKNDMMVYCSFCGKNQEEVQKIIAGNNAFICNECVELAQE
                     IIREELVEEVLADLSEVPKPIELLHILNHYVIGQDRAKRALAVAVYNHYKRINFHDTR
                     EESEDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATALTEAGYVGEDVEN
                     ILLKLLQVADFNIERAERGIIYVDEIDKIAKKSENVSITRDVSGEGVQQALLKIIEGT
                     VASVPPQGGRKHPQQEMIQVDTKNILFIVGGAFDGIEEIVKQRLGEKVIGFGQNNKAI
                     DENSSYMQEIIAEDIQKFGIIPELIGRLPVFAALEQLTVDDLVRILKEPRNALVKQYQ
                     TLLSYDDVELEFDDEALQEIANKAIERKTGARGLRSIIEETMLDVMFEVPSQENVKLV
                     RITKETVDGTDKPILETA"
     gene            21045..21632
                     /locus_tag="VQ862_000771"
     CDS             21045..21632
                     /locus_tag="VQ862_000771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002915299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihA family ribosome biogenesis GTP-binding
                     protein"
                     /protein_id="HET3115145.1"
                     /translation="MELNIHNAEILLSAANKSHYPQDELPEIALAGRSNVGKSSFINT
                     MLNRKNLARTSGKPGKTQLLNFFNIDDKMRFVDVPGYGYARVSKKEREKWGCMIEEYL
                     TTRENLRAVVSLVDLRHDPSADDVQMYEFLKYYEIPVIIVATKADKIPRGKWNKHESA
                     IKKKLNFDPSDDFILFSSVSKAGMDEAWDAILEKL"
     gene            21643..22023
                     /locus_tag="VQ862_000772"
     CDS             21643..22023
                     /locus_tag="VQ862_000772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RidA family protein"
                     /protein_id="HET3115146.1"
                     /translation="MAKTIHTDKAPKAIGPYVQGKIVGNLLFASGQVPLSPETGEIVG
                     ENIQEQTEQVLKNIGAILAEAGTDFDHVVKTTCFLSDMNDFVPFNEVYQTAFKEEFPA
                     RSAVEVARLPRDVKVEIEVIAEIG"
     gene            22075..22965
                     /gene="rapZ"
                     /locus_tag="VQ862_000773"
     CDS             22075..22965
                     /gene="rapZ"
                     /locus_tag="VQ862_000773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNase adapter RapZ"
                     /protein_id="HET3115147.1"
                     /translation="MTKKQLHLVIVTGMSGAGKTVAIQSFEDLGYFTIDNMPPALLPK
                     FLQLVEIKEDNPKLALVVDMRSRSFFSEIQAVLDELENQDGLDFKILFLDAADKELVA
                     RYKETRRSHPLAADGRILDGIKLERELLAPLKNMSQNVVDTTELTPRELRKTLAEQFS
                     DQEQAQSFRIEVMSFGFKYGIPIDADLVFDVRFLPNPYYLPELRNQTGVDEPVYDYVM
                     NHPESEDFYQHLLALIEPILPSYQKEGKSVLTIAMGCTGGQHRSVAFAKRLAQDLSKN
                     WSVNEGHRDKDRRKETVNRS"
     gene            22962..23939
                     /locus_tag="VQ862_000774"
     CDS             22962..23939
                     /locus_tag="VQ862_000774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YvcK family protein"
                     /protein_id="HET3115148.1"
                     /translation="MRKPKITVIGGGTGIPVILKSLREKDVEIAAIVTVADDGGSSGE
                     LRKNMQQLTPPGDLRNVLVAMSDMPKFYEKVFQYRFSEDAGAFAGHPLGNLIIAGLSE
                     MQGSTYNAMQLLSKFFHTTGKIYPSSDHPLTLHAVFQDGTEVVGESHIVDHRGIIDNV
                     YVTNALNDDTPLASRRVVQTILESDMIVLGPGSLFTSILPNIVIKEIGRALLETKAEI
                     AYVCNIMTQRGETEHFTDSDHVEVLHRHLGRPFIDTVLVNIEKVPQKYMNSNRFDEYL
                     VQVEHDFVGLCKQVSRVISSNFLRLENGGAFHDGDLIVDELMRIIQVKK"
     gene            23936..24847
                     /gene="whiA"
                     /locus_tag="VQ862_000775"
     CDS             23936..24847
                     /gene="whiA"
                     /locus_tag="VQ862_000775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein WhiA"
                     /protein_id="HET3115149.1"
                     /translation="MSFTVAVKEEILGQHHLSRHELSAIIKMSGSIGLSTSGLTLSVV
                     TENAKLARHLYESFLHFYEIKSEIRHHQRSNLRKNRVYTVFTDEKVQDLLSDLHLADS
                     FFGLETGIDEAILSDEEAGRAYLCGAFLANGSIRDPESGKYQLEISSVYLDHAQGIAS
                     LLQQFLLDAKVLERKKGAVTYLQRAEDIMDFLIVIGAMQARDDFERVKILRETRNDLN
                     RANNAETANIARTVSASMKTINNISKIKDIMGLENLPVDLQEVAQLRIQHPDYSIQQL
                     ADSLSTPLTKSGVNHRLRKINKIADEL"
     gene            complement(24935..26062)
                     /locus_tag="VQ862_000776"
     CDS             complement(24935..26062)
                     /locus_tag="VQ862_000776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000266845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HET3115150.1"
                     /translation="MWMEELPNGKFKYFERYKDPYTEKLKKVSVTMEKKTPQARNQAA
                     ILLQEKINKKLSTKQVESITFEEIYNLFYKSWAQTVKESTKHNCKSVDKKMKEVIQSD
                     TILANLDRRFLQEAIEKIIESNGYITAKKVRHRLRGIFNYAVQYSYIENNEVDYTTIP
                     QKPKTLEELEKKRNNFLTMQEIKALVDVLNRREYHQKYADMVLVLTLTGMRYGELTAL
                     QLKNIDFENNKIEITGNFDSVNKIKTLPKTTNSIRTIKVSESVIEAIQRQIVRLSERF
                     QPLSSDDYIFCFEKWNQPTTIACFIQILKKYGKQAKIEKNLSSHIFRHSHISFLAESG
                     LPIKSIMDRVGHSNAKMTLEIYSHTTEDMEDKLVNKLDTIF"
     gene            complement(26341..27291)
                     /locus_tag="VQ862_000777"
     CDS             complement(26341..27291)
                     /locus_tag="VQ862_000777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000802056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Abi family protein"
                     /protein_id="HET3115151.1"
                     /translation="MKPFKTIEEQIATLKIRGLSITDESKAAKYLLSNNYYNIINGYS
                     KFFQHPGTDTYIDGVTFDEVSSLYTFDKDVKRAILQAILEAEHHIKSITAHRFAEAYP
                     SQKYAYLNTNSYADNKILDVGFIVSKLSKIINTNKRYRGNSIHHYAHTHSDVPIWVLT
                     DYLEFGDLRTIIENLPNSLQNEIARDLVSFISTNIPDFNDVFPPETLISFLKNINEVR
                     NKCAHNNRLLNFRCRSNSTFWETIHNKEILMGDDSRKTVYSTIISLQCFISKAAFNIL
                     WNTLRKKVIKLEKKLPSIDINVINQSLGFPNDWHRNEPKV"
     gene            complement(27440..28231)
                     /locus_tag="VQ862_000778"
     CDS             complement(27440..28231)
                     /locus_tag="VQ862_000778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000343639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HET3115152.1"
                     /translation="MDEKKRMQIIAENITHFRKQRGITQKELAKEVGITASTMTDYMK
                     LRSAPSFGVIQKLADYFGVKKSDIDTTFKEESTNSLPDAPDSLTQQIMDKVVQLTPPN
                     QKIVLRTSEELLESQNEEETKINEVSEVISLYQVEVVSETAAASGFNYGFGYDDTDRE
                     TIEVDERPPRHDIATKVSGDSMQPDYQDGDILYLVDKGLTTYNGDLAVIAYGDRSYFK
                     KIYTENGRLRLVSLNDKYEDIILDFPPAEDTHIKIYAVVGVYRGE"
     gene            complement(28475..29164)
                     /locus_tag="VQ862_000779"
     CDS             complement(28475..29164)
                     /locus_tag="VQ862_000779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018165612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4145 domain-containing protein"
                     /protein_id="HET3115153.1"
                     /translation="MIFRVKVNSSVSRPVTVEDICPNCKKPTNPDLVNSSYFSLGENK
                     TSLVLTCRCLGCKHFWTEEFIATRFLINDYTEKYEIEHIKVIPNLPSDIPISDDVEIV
                     SPIGKQIYVQALKAEHEQLDHIAGIGYRKALEFFVKDFSIVTNPDDEDKIIKMSLKQV
                     IEKYIKDEDLKTFALASAYIGNDEGHYYRNNPDKGFTDLKNYLHGVIHYMEMKLNFLD
                     AQELVNRSKKS"
     gene            29371..29535
                     /locus_tag="VQ862_000780"
     CDS             29371..29535
                     /locus_tag="VQ862_000780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000662050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3115154.1"
                     /translation="MKENIEHLHERIKHFQSLIAYMSEHEKKYYLEKDWFDNPTLISI
                     EDAKKEVELL"
     gene            29554..29769
                     /locus_tag="VQ862_000781"
     CDS             29554..29769
                     /locus_tag="VQ862_000781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001198773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET3115155.1"
                     /translation="MQWTLEAMRINKGLTQAELAEKFEVSSQTIARLEKDSSDIGYQL
                     LKKYMFFFNVKFDDIFLGKKYENFVNN"
     gene            29801..30001
                     /locus_tag="VQ862_000782"
     CDS             29801..30001
                     /locus_tag="VQ862_000782"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3115156.1"
                     /translation="MESVLESLKQEKDHLEKIIKVVTSGGKFLRLPYQKKSRSISENL
                     KLISQNLDKLSEQVQQTTNQHS"
     gene            complement(30401..30592)
                     /locus_tag="VQ862_000783"
     CDS             complement(30401..30592)
                     /locus_tag="VQ862_000783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000834563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3115157.1"
                     /translation="MKSFKDFRESLTAEDMQAISAKANEATKQIDHTDGLQLGKVSGL
                     TSVITTIELLEKYHEWLHS"
     gene            30851..31021
                     /locus_tag="VQ862_000784"
     CDS             30851..31021
                     /locus_tag="VQ862_000784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000660186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3115158.1"
                     /translation="MKEAVKEFLKFRSRFTKIEWFEINQAVEARLNQKADQLKLDDVD
                     LEIISSRLEKVI"
     gene            complement(31014..31253)
                     /locus_tag="VQ862_000785"
     CDS             complement(31014..31253)
                     /locus_tag="VQ862_000785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000134992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3115159.1"
                     /translation="MTEIHACLCGNWVNLSADDDCVMGPNMASPYIWWEENAELYSPI
                     SKPEANSMYHQDYIYIHYRGADYRIHPMFIQIVSR"
     gene            31371..31643
                     /locus_tag="VQ862_000786"
     CDS             31371..31643
                     /locus_tag="VQ862_000786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000388508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3115160.1"
                     /translation="MEAVEIVRIKDVIIEKVSANDEELKRIFGCSKRQAGERRREMQK
                     LPSQQKHLLDSGQLVTIKGFYEYLQYRGTKAWKKEMETSKKMRSAG"
     gene            31640..31855
                     /locus_tag="VQ862_000787"
     CDS             31640..31855
                     /locus_tag="VQ862_000787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001050925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3115161.1"
                     /translation="MNLLSRIKNYFSEEVKETNLDWKEVALDLNQSLIETQEKLQEAN
                     QEIADLKKIVAIYKEKEKEKRWNIFTW"
     gene            31834..32022
                     /locus_tag="VQ862_000788"
     CDS             31834..32022
                     /locus_tag="VQ862_000788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3115162.1"
                     /translation="MEYIYLVTIVGIGLWSLVNKLDDHAEMKQKERQLMANNVARMNL
                     RNSDKQFTYDVEPPEGLK"
     gene            32162..32740
                     /locus_tag="VQ862_000789"
                     /pseudo
     CDS             32162..32740
                     /locus_tag="VQ862_000789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000544345.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
     gene            32733..33215
                     /locus_tag="VQ862_000790"
     CDS             32733..33215
                     /locus_tag="VQ862_000790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siphovirus Gp157 family protein"
                     /protein_id="HET3115163.1"
                     /translation="MASLYELTGQFLTIYQLDIDDETKADTLEAIDWQEQFEQKAEGY
                     AYVIKNLEADVAMYKAEEESFKAKKQVAQKKLDYVKDNIMAAMNVTGQTEVKSGALII
                     KIAKNPESVKVNEDDLPKKYFTKKVTLAPDKKTLKELLKSGKKVKGAELVRTEKLVIK
                     "
     gene            33215..33574
                     /locus_tag="VQ862_000791"
     CDS             33215..33574
                     /locus_tag="VQ862_000791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000422310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3115164.1"
                     /translation="MELMNKTRVTDSLAVVIGPESIEVLVTEGFLFDVAIRFVKVDET
                     NLDQGNEKPVFTPEYKLVTVAKYKEKPIFESEEDIRKFEKQAKEVKSLFAFAKVNKQN
                     WFNTALYPGVLTEKVGV"
     gene            33574..34059
                     /locus_tag="VQ862_000792"
     CDS             33574..34059
                     /locus_tag="VQ862_000792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000696057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3115165.1"
                     /translation="MKILAIDPSSNKIETSTTGVVLLDNARLVDSWVVSYGMRGFADW
                     FHEIGTNLEFDVVIVEEFKARDNDKSKDNSVAETIAYIQLCYPGAILQFNAGYKSDIP
                     NDLLKILDLWKFEKSHHQDIRAAARLGLFWAMRNDIEEVVHDIGKVVSEYHNNAKKVA
                     S"
     gene            34022..35215
                     /locus_tag="VQ862_000793"
     CDS             34022..35215
                     /locus_tag="VQ862_000793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III restriction endonuclease subunit R"
                     /protein_id="HET3115166.1"
                     /translation="MSITITLRKWQAEAIKRSEHLSNGIFLEALGGRGKTICALAIAK
                     HKKAKKIIITNNRLAILNGWIDAVKFMNFDKGVEIIIQTDRYLQNQVKKGHKLDCDVL
                     IVDEWQNMSSDKQVALYRKIKRKYTIGLSATPIRKKGQNFYPLEKTVFGWATPNNKFD
                     WQKTHGKMVYDPFSYSKEKWEDFQNYESYISSLPNFFRWEDIEKIENATENNGFETKF
                     YPVTVKAGNPEKLAEFRQLNLVTVGDKTAMAKQSFGRKTFERYLNQTGVIVDFPKLKP
                     VNADTPLMLKLDGLIERAPHDMLIVSKSKQIVNVISERHPEIGIWTGDIQEGLYKKFV
                     VATSQVLGVGVDGLQHKYQTIVVLDPVEEGSGEYDDYRQLLWRITGSRQQHDVNVIEF
                     YYKES"
     gene            35234..35551
                     /locus_tag="VQ862_000794"
     CDS             35234..35551
                     /locus_tag="VQ862_000794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001044593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3115167.1"
                     /translation="MNKTTEMIVFRSRKTGEFLNSYKDRSSLAFAADFCSLEYCLKLP
                     RKKYEDNKKTYKALAAAFDYEIVAVEAEYKLTYPNGSEVEPIKRDRSSIEDMIKDIIG
                     GVL"
     gene            35551..36378
                     /locus_tag="VQ862_000795"
     CDS             35551..36378
                     /locus_tag="VQ862_000795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000885998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HET3115168.1"
                     /translation="MAFTLPANKPQVPKDTPRNFFIYGETMSGKSYLANEFPNPIVLN
                     TDGNAEANTVPSIQLINEKDDKGRITNSVIKQLGDILLALQTQKHSYETVVIDVIDDV
                     IEMIKIAVCDELTPVGKPRLKSLSEIPYGKGYDFFNQAITELVIDLKALPMNVIYISR
                     QVSEYDDNGNATKDKPSLKDKYVNLINGNSDLMIHTEKLGNNYNREVDRKRKTYYADQ
                     VDDKAILKILATIRGAVEPAKGKLAPKKEAAKTTKPAKTEKTKEAPKKEVDSDDELF"
     gene            36398..36901
                     /locus_tag="VQ862_000796"
     CDS             36398..36901
                     /locus_tag="VQ862_000796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000054338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3115169.1"
                     /translation="MSLLDIAKSIKKEGFDPRKDSANGPAPIPAGTYPVVLKKATFNV
                     SDKGWESLGYQFEIRGGDYSGRSEFATFGTLTEWNGKNLDWAVERTMKFFIKALVLAG
                     DSMQGNEEDGKALEEALKRKAVGSYYNLVISVTKGKDGREFRNYDLEEEAQPLTEADI
                     DDDDLPF"
     gene            37074..37895
                     /locus_tag="VQ862_000797"
     CDS             37074..37895
                     /locus_tag="VQ862_000797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001139684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional DNA primase/polymerase"
                     /protein_id="HET3115170.1"
                     /translation="MPSMKEYALQYQKLGFSVIPINPKNKMPLINFADKPAMTPSEIE
                     NFWDGYPNANIALKTTNFFVIDIDKHGKSNGFKSLKKWKHLNLIEPTLQAKTASGGKH
                     LFYFKREDEPITQMIGFLPGVDIKAHENNYVLVAPSATDKGQYEWDLEKSKEGGTMVT
                     PSKYLIQSIKKQYGETHGYKYDGKDGLRDLVRRSHTRDRTQTTDLFETIALGFGDEGG
                     RNDKLAKFVGGLLYRAVDDGVVVQLARLANANSPTPLPEKEMMRTIESMIKKDRR"
     gene            37898..39241
                     /locus_tag="VQ862_000798"
     CDS             37898..39241
                     /locus_tag="VQ862_000798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000580032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase"
                     /protein_id="HET3115171.1"
                     /translation="MIGNVVSIDSQPKMITTAKGDIKANSPSNVLMSFKADDQLSIYL
                     KHNDFSQEHELLKDIKIGNTLFKKGELPSNFDSVVKVYFESVLGVAFSSQAMLDGMET
                     FFSERSYNPVIEYMEKAAEKWDGRKRIDRMLQVYLGAEDIPLVSKIAQMWLVGAVAKV
                     YDPYVKFDYVLDLVGGQGVGKTSLLQKLGGEWYTDAVTDFSNKDNYDIMLKSLIVNDD
                     EMVASNRMSFAETKAFISKTSLRYRKPYMKRTEEFAKNFILARTTNQTEYLKDKTGER
                     RFLPVMADSKRQKKHPMEIEPETIEQIWGEAVTIYRAGADLMFDENTEDELNIYREQF
                     MYRDEVELQVLEYLDMPVPENWQNWSIQQQHQYTSKYFDNSSDFDPGSKKLDKVSTRE
                     MMYNLFMRNSNDRKLSTKINMIMDNHPDWKKSVFRAGGKSTKGFVRVKDSEKTNR"
     gene            39534..39689
                     /locus_tag="VQ862_000799"
     CDS             39534..39689
                     /locus_tag="VQ862_000799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000122744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3115172.1"
                     /translation="MSYTVTLFFDNMVDETHFFKKESDAAKCKAQLESKYRGNRMYKV
                     KQEKLEE"
     gene            39686..>39993
                     /locus_tag="VQ862_000800"
     CDS             39686..>39993
                     /locus_tag="VQ862_000800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001041166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1642 domain-containing protein"
                     /protein_id="HET3115173.1"
                     /translation="MNKQELIKRIEDLPYTEGPIADTIEINRNWILKSIEQLAESEIG
                     HADEAPRYVKNILARLRELPLHDREFWLKAIMSEFEQDFSHAKWREGYEQGKIEGMVE
                     R"
BASE COUNT        12532 a         7108 c         8677 g        11676 t
ORIGIN      
        1 aagaaagaca gaaattgttc aagaattaat gactgagttt tcgttagttc ttcttctaaa
       61 agccattaaa ctagctcgtt cgacctacta ctatcacttg aaacagctag acaaaacaga
      121 taaggactaa ggctggcaat accaacacga ttcttatcat cggttcctag agagtaaggg
      181 aattcaagca tctatgtcac gcaagggaaa cagccaagac aacggtatga tggagtcctt
      241 ctttggcatt ttaaaatccg aaatgtttta tggctatgag aaaacattta aatcacttaa
      301 tcaattggaa caagccatta tagactatat tgattattac aacaataaga aaattaagtt
      361 aaaactaaaa ggacttagcc ctgtgcaata cagaactaaa tccttcggat aaattaattg
      421 tctaactttt tgggggcagt acacaatacc tgatagtatg cgttttattg tgggaagatt
      481 ttcctcattt tctagtgaaa ttgaactttt tctaacatct tttgatagat gacttcttaa
      541 tcaattatca tttccattgt tgtttcttgg ggtttcatcc cttgtctttg ataaaagcgg
      601 agagcaccct cgttatcatt ccagacactt agggttagat tattgcagcc aatttcttta
      661 gcataatagc agaaaaatga caataaaata gcccctagat attttgaaag gaaagcatag
      721 gggctatata gtttaatcaa aataaagcaa atctttgctg gtgcttgtaa agaggtcgaa
      781 gccatccttg gtaacaacac cgcagtcttc aatacgaaca ccgactttac cagggatata
      841 gatacctggt tcaacagaga agcacatgcc ttcttcgatg accatgtcgt ttccttccat
      901 gatagatggg aattcatgga catccatacc gataccatgc ccgagacggt gattgaagta
      961 ctcaccataa ccagcttttt cgatgacctc acgggcagcg cggtccactt catgagcagt
     1021 cacacctggc ttgataaagt caagagcagc ttgttgggct tcaagagtca agttgtaaat
     1081 atctttcttg aattggtctg gtttgccgac agcgactgta cgagtcatat ctgacgcata
     1141 gccattgacc agaacaccca ggtcaaagag gagaagagca tcattttcaa ccttattagc
     1201 tgctggaatg ccgtgtggat tcgcagcatt atcaccagtc aagaccatgg tatcaaagct
     1261 catttcataa ccttcacgtt tcatggcaaa gtcgatttgt gcgatgatat ctgtctcagt
     1321 cttatcaaga gaaatattgt caaaaccaac atgaacagcc ttgtcagcat aaagacctgc
     1381 aaccatcatt ttttgcactt catcagctga tttgatgagg cgcatgcgtt ggatacgagg
     1441 agtgaggttg tcaaactcag cagtctcaaa aactgttttc aaaccatggt atttggtcaa
     1501 gatgagattg tcaaactcaa cagcgacacg tttgaagtca agttgtggaa gagcatgttt
     1561 gattttttgc catggatttt cagaatcgac atagcccact actgggaagg aaacggtgct
     1621 acttgcacgt tctacttcaa gagctgggac aaagaggaga ggttcctgat ccgctaggac
     1681 aaagaggaac atttggcgtt catggggatc actgtaaaaa ccagtgaggt aattgattgt
     1741 gacggggtca gatacgacag cgacgtctag tttttctgat tcaagatatg ttaggatttg
     1801 ttgtaattta gacatatgct accttctttc tacccctcta ttttggcaaa aaatgagaga
     1861 aaatgcaagg gagaagggta aaagaaaaga caaaaaactc cgacaagata acggagttct
     1921 ttgatatcat tttcctttgt ttaagaaaag tcagccttgc ttttgacgtc actgtactct
     1981 tcagcgattt cttggctgag gatatcctca taggcaggga gttggatatc ctgaccatat
     2041 ttcttcttga gggcagtagt aactaggcga taagccagat tggcattacg agagaggata
     2101 ggcccgtgga agtaggaacc aaagacattc ttataatgaa ccccttcacc gaccttttct
     2161 tcgttgtttc catttccata gacaacctgt cccagcggtt tttggtcatc agagaggaag
     2221 gtacggcctt ggtgattttc aaatccatag taggtttcat cgaaatcttc attgtgaatc
     2281 ttgatgtcac cgataaaacg gttattggtc tggttgagcg tgtagtgtcc catgacccct
     2341 agcccttcga tacgttttcc tgaagcttca acataatatt gacccaatag ttggaaacca
     2401 ccgcagatag ccagaactac accgtcgttt tggatgtagt tgtcaatgct ctctttttta
     2461 gcaggtaggt cgtctgcaat gatactttgt tcaaagtctt gaccaccacc gaaaaaggcg
     2521 atgtcgtagt gattttcatc aaagtcatca tggagagaaa cgatgtcaac ggtcacatgg
     2581 gctcccagtt tttcagccac atatttgagc atgaggatgt ttccattgtc cccgtaggta
     2641 ttcatgagat ttccgtagag gtgggcaatg ttgagctgat aggggtaatt gccatctttt
     2701 gaggaaagtg aagtataaac cattagttca tctcctttct aacaatctga cgactagcca
     2761 gcagttcacg aaattccagc atggcagtat aagttgccag aatataggca tgcttgcagt
     2821 cttgattctc aatggtcttg agaacttgct ccagattact cgtttcagtg attttctcag
     2881 ctggatagcc agtcactcgg aggcgacgag cgatttcaga atgacgaaca ccgccagcgt
     2941 tgatttcagg aatgtccatg tcagtgattt gctcaaagtc tgcatcccag atccagctag
     3001 tgtcaattcc atctgcatag ttggcattaa ggaggacaga taggctaaat ggataaggtg
     3061 ctagtttgat catttcgata gcttgggttg caccgactgg atttttaatc aagacaaggg
     3121 tacatttctt gtcaccgata tgaaaggttt cttggcgtcc aaagacagca cggctcttgt
     3181 caaatccctg tttgatgagt tgcgaatcgg cacctaggaa acgggcgatg gccacagcag
     3241 ctagggcgtt atagatatta tagagcccgc cgatttggat accgtattct tggccgtcta
     3301 tgacaaagcg agagcgattg ttggtcaact caaccagttt tgtcaaacga tagtcgagat
     3361 caggacgttt acatccacaa ccttcacaga tataggcacc caagtttgca taggtattat
     3421 gctcatattt gaggatgcct tggcagtcag gacagagaat cccttcggta ttgtagtgag
     3481 ccagttgggc tggtcctttt tccaagtcaa aaccaaaata ctctataggg tttggaatag
     3541 ttggcttgta gaaaagtgga ctgtctccgt taaggagaac agtagcagtt ggaacttttc
     3601 gaatggcatc caatatcatg ttataggtag tatagatttc accgaaacgg tccatctggt
     3661 cacggaagat attagtaatg acaaaaagac taggctggat atagtcacag atacgagata
     3721 gactggcttc gtcaatttcg aggacggcaa tatttttccc agtttttgaa gatttggctg
     3781 ttaggaaggt tgttgcaatc cctgtaatca tgttggcacc gcttgggttg gttagaactt
     3841 gaccataaac ctcttttaaa atgccgacag tgagggcagt tgtcagggtt tttccatttg
     3901 ttccagtgac aacgacaatc tcgtagttct tagctaggtt ttgtaaaata tctttatcaa
     3961 attgaagggc gactttacct gggagcgtac ttccacgtcc aagacggctt aaaacgaagt
     4021 gggaagaacg cccagcaaga aggcccaaag tagtttttaa gttcatgttt ctattatatc
     4081 acaaaagagg gaaaagacag atttggtgtt tcgtagaagt aaaaacagcc caaagagggc
     4141 tgtcagttaa gatgagattt caacttaaat cgcaaacaag tcattcaagt tctcagccaa
     4201 ggttgggtga gtgaagattt gttttgtgaa gtaagtgtaa ggaatcttgt tgtccatagc
     4261 aacagtaatg atgttgatga tttcttgaga accttctgag aagatgcttg caccaagaat
     4321 ttcttttgtt tcagtattaa caacagcttt gaaagctccg cgaaggtctc catttacgtg
     4381 accacgaggc atggctgcaa cagggatttc tttcactgcg tatggaagtt tcaaatcagc
     4441 tgcttggctt tcagtcaaac caacttgtga aagtgcaggt gtgatgaaca tagtatttgg
     4501 cacattgaga cggtcctcaa gtgtgtagct gccatctcca gcaaggtagc tgtaaacaac
     4561 acggaagtca tcaagtgaaa tgtaagtaaa ttgaagacca ccgttgacat ctccaactgc
     4621 aaagacacca ggaacgtttg tttgacagtg tttatctact ttaatagcgc cacgttcagt
     4681 tagttcaata tctgtatttt caagttgaag tggttctaca tttggtttgc gtccagttgc
     4741 gtagagaagg gcgtcgaaac ggtaagtttc gtcttcagtt acgacaagca cttggtcacc
     4801 gtcgttttta atttcagtag tatggatatt ttgaagcaat tcaataccgt cttcttccag
     4861 gtattgttta gcaagagctg cgatggaagg ttctgcacga ggtaggaatg tatccaaggc
     4921 atctaggact gtaaccttgc ttcctagttt attgtaaagg ccagcaaatt caagaccgat
     4981 atttccgcca ccaaggactc caagtttttc aggcaattta tccaagcttt ggatacctgt
     5041 tgagtcaaag acgtttttgc ttgtagcaag tccagggatt ggcaagacgt ttgaaacagc
     5101 accagtgttg atgacgatag tttcagcagt caattcttgt ttttcatcac cagcttggat
     5161 ttcgatgact ttatttgaaa ggaagtgagc ttcagcatca aagatattga cgccagtacc
     5221 agcaacagtc gtatagtttt taccgttgag gcgaccagtg atcgtgtttt tggtagcaat
     5281 gacttcttca aaagacaagt ctttctcagc agcaaccagc aaagttttag ttgggataca
     5341 accgatgttg atacaagttc caccgtacat agctttgcta cgttcaacga gggcaacttt
     5401 tttgccagct gaagccaatt taccagctag tgttttacca gctttaccaa atccgataac
     5461 gattaaatca taagttaaca tttagaattc ctcctattcg aattacattc tagcacaaga
     5521 aaaaaacttt tgcacaattc tgctacgaaa aagacagaaa aagatgaaaa cgctttccag
     5581 acaaaaaact agtaattttt tgacaagctt gataaactaa aatcctatct atttttatat
     5641 aataaagaat aaatgttcga aaataggagg ttttatgaaa tcgaatcgtt atattattgc
     5701 ctttgctggg gtcattttac acttaatgct gggttcgact tatgcctgga gtgtttatcg
     5761 taaccctatt attgaaaaaa cgggatggga tcaggcttct gttgccttcg cctttagtct
     5821 agcaatcttt tgtttgggct tatcggctgc atttatgggg cgtttggtag aaaaatttgg
     5881 tccgaaagtc atgggaagtc tatctgcttt tctatacgca ggtggaaata tcttaacagg
     5941 atttgcaata gaccgtcagg agctgtggtt gttgtatctc gcttatggca ttttaggtgg
     6001 gcttggtttg ggagcaggct atattacccc tgtgtcgacg attataaaat ggtttcctga
     6061 taaacgtggt ctcgcaacag gtttagcgat tatggggttt ggttttgctt ctttattgac
     6121 tagtcccata gcgcaacacc tcatcgcagg ggtagggctt gtagaaactt tttatatttt
     6181 aggagcaagt tactttatta tcatgctcct agcttcacaa ttcattaagc gtccaaatga
     6241 gcaagagctt gcaattttat cttcttcagg gaaagaaaaa acagcctctt tgacgcaagg
     6301 aatggctgca aatcaggctc taaaaagcaa tcggttttat atgctttgga ttattttctt
     6361 tatcaacata gcttgtggtt taggcttaat ttcagcggca tcgccaatgg cacaggagat
     6421 ggctggcttg tctacaagtc atgcagcagt aatggtgggt gttttgggga ttttcaatgg
     6481 atttggtcgc ttgctctggg cgagtttgtc tgactatatc ggtcgccctc taacctttag
     6541 tatattactg cttgttaatc ttttcttttc tctctcactt tggctcttta cagattccgt
     6601 tttatttgta gtcgctatgt ctattttgat gacttgctat ggagctggtt tttcattgat
     6661 cccagcttat ctcagtgata tttttggaac caaggaattg gccgctctgc atggatatat
     6721 tttaacagct tgggcaatgg ctggtttagc gggacctatt ttattagcag agacttataa
     6781 aatggctcat tcgtacacac aaaccttgtt cgtttttctc attttataca gtatcgcctt
     6841 ggctttgtct tattatctag gtcgttcaat caaaaaagaa agtcaaaaac cgcttacatg
     6901 attttctgta gaaatgggac tatcttttgc tctggtcttg tgttatacta gataggttgc
     6961 aaagaaaaca gtacttttct tttgtggaaa agaagcaaca cgattttata tctagttata
     7021 tgaaaatacg tcataaaaag aaaagtataa actaagccct atagggtggc ttcgcaccac
     7081 ctttagaaag aagaataacg tgaaatttaa tgaattaaac ttgtctgctg atttgctggc
     7141 agaaattgaa aaagctggtt ttgtagaagc tagtcctatc caagaacaaa ctattccttt
     7201 ggcccttgaa ggcaaggatg ttatcggtca agctcagact ggtacaggaa aaactgcagc
     7261 ctttggcttg cctacccttg aaaaaatccg tacagaagaa gcgactatcc aagccttagt
     7321 catcgctcca actcgtgaac tagctgtcca aagtcaagaa gaactcttcc gctttggtcg
     7381 tagtaaggga gtcaaagtcc gttcagtata tggcggatca agcattgaaa aacaaattaa
     7441 ggctcttaaa tctggtgccc atatcgtggt gggaactcca ggtcgcctct tggacttgat
     7501 taaacgcaag gccttgaaat tacaaaacat tgaaaccctt atccttgacg aagcggatga
     7561 aatgcttaac atgggcttcc ttgaagacat cgaagccatt atttcccgtg tacctgagaa
     7621 ccgtcaaact ttgcttttct cagcaactat gccagatgcc atcaaacgta tcggtgttca
     7681 gtttatgaaa gcccctgaac atgtcaagat tgcggctaag gaattgacaa cagaattggt
     7741 tgaccagtac tatatccgtg ttaaggaaca agaaaaattt gacaccatga ctcgtctcat
     7801 ggatgtggca caaccagaac tcgctattgt atttggtcgt accaaacgcc gtgtggatga
     7861 attgactcgt ggtttgaaaa ttcgtggctt ccgtgcagaa ggaattcatg gcgacctaga
     7921 ccaaaacaaa cgtcttcgtg tccttcgtga ctttaaaaat ggcaatcttg atgttttggt
     7981 tgcgacagac gttgcagcgc gtggtttgga tatttcaggt gtgacccatg tctacaacta
     8041 cgatattcca caagatcctg agagttatgt tcaccgtatc ggtcgtacag gtcgtgctgg
     8101 taagtcaggt caatctatta cttttgttgc tccaaacgaa atgggttacc ttcaaatcat
     8161 tgaaaacttg actaagaaac gcatgaaagg tctcaaacct gcaagtgtag aagaatcctt
     8221 ccaatcaaaa aaacaggtag ctctcaagaa aatcgaacgt gattttgcag atgaaaccat
     8281 tcgtgccaat tttgagaaat ttggtaagga tgctcgcaaa ttggctgctg agtttactcc
     8341 agaagaattg gcaatgtata tcttgagtct gacagtccaa gacccagata gccttccaga
     8401 agtggagatt gcacgtgaaa aaccactacc gtttaaacca tcaggtaatg gtttcggtgg
     8461 taaagctaag ggaggtcgtg gaggccgtcg tggggacgac cgtcgagagc gtgatcgccg
     8521 tggcaatggt cgccgtgatg agttcaaaaa aggaagtcgt ggcaacgatc gttttgataa
     8581 ggaaaaacgt taccgtaagg ataataaaaa accacgcaat actttaagcg aaaagcaaac
     8641 aggctttgtt attcgtaaca aaggtgataa ataagaaaaa gcggttcaaa atgaatcgct
     8701 tttttatata aggagaccga atgtgaaaaa gacaaataaa attattatat tatcttttat
     8761 aatattatga tacacaaaaa taggcaactt gtcaatagaa aaggaacaat ttaattaaaa
     8821 atattctggt ttttaattaa attgtaagtc aatgcaagtc aataaggaat tttcagataa
     8881 ttattgaaaa agagacgttt ttatgttata atgatagcga ttaaattcga ggtgaaaaat
     8941 ggcacattta ttagaaaaaa ctagaaaaat tacatcaatt ttgaaacgct cagaggagca
     9001 gttgcaggat gagcttcctt acaacgctat tacgcgtcag ttagcggata ttattcattg
     9061 caatgcctgc attatcaata gtaagggacg tctgcttggc tattttatgc gttataaaac
     9121 aaatacagat cgcgtagagc aattcttcca aactaagatt ttcccagatg actacgttca
     9181 aggggctaat atgatttacg aaacagaagc aaacttacct gttgagcatg atatgagtat
     9241 tttccctgtt gagagtagag atgattttcc agatggcttg acgactattg caccgattca
     9301 tgtatcgggg attcgccttg gttctttgat tatttggcgt aatgataaaa aattcgaaga
     9361 tgaggacttg gttcttgttg agattgccag taccgttgtt gggattcagc ttcttaactt
     9421 ccaacgtgaa gaagatgaga aaaatattcg tcgtcgtact gctgtcacca tggcggtcaa
     9481 taccctttct tactccgaac tccgtgctgt ttcagcaatt ttaggggaat taaatggaaa
     9541 tgaagggaag ttgactgcgt cagtgattgc agatcgtatc ggaatcactc gctctgtgat
     9601 tgtcaatgct cttcgtaaac ttgagtctgc ggggattatt gaaagtcgct cacttggaat
     9661 gaagggaacc tatcttaagg tcttgatttc agatattttt gaagaagtga agaaaagaga
     9721 ttactaatga caaaggcttt aatttcgatt gattatacag aagattttgt tgctgatagt
     9781 gggaaactaa cagcaggtgc tccagctcag gcgatttcgg atgccatcag caaggtaact
     9841 cgattagctt ttgaacgagg agattatatc ttctttacta ttgatgctca tgaagaaaac
     9901 gattgtttcc atccggaaag taagttattt cctcctcata atctgattgg gacgagtgga
     9961 cggaatttat atggagattt ggggaacttt tatcaagagc atggttcaga cagtcgtgtc
    10021 ttttggatgg ataaacgcca ttactcagct ttttcaggga ctgacctaga tattcgtttg
    10081 agagagcgta gagtgtctac cgttatctta acaggtgtct tgacggatat ctgtgtccta
    10141 catacagcta tagatgccta taatctagga tatgacatcg agattgttaa accagctgtt
    10201 gcttccatct ggcctgaaaa tcatcaattt gccctaggtc atttcaaaaa tacactcgga
    10261 gctaagttag tagatgaaaa tctaaatgaa ctttctgagt aacctggttg gtgaaaatga
    10321 aaaaatttga aaaaaagtgt tgacaagcat cccaaaagtt gatatactag taaagtaatc
    10381 gatgcgggga tggcggaatt ggcagacgcg caggactaag gatcctgtga ccgctttagg
    10441 tcgtgagggt tcaagtccct ctctccgcat aggaaaagag ttagctaaag ctagctcttt
    10501 tgtatttctc taaaaaatta gaatccagtc aaatgtagtg gagaatcagc gaaaatatgg
    10561 gaaaactgat ccttgtttct gcttttgtca tagaagaata ataaagatta tcttcttcaa
    10621 attctccgat attctctaaa gttttgtgca agttgcacag aactttttta tttttttggt
    10681 catcttgcca tagaaatata aagcgttttc atatataata taattatcaa aagacaaaag
    10741 gagttcacct catggtagaa ttgaatctta aaaatattta caaaaaatat ccaaacagcg
    10801 aacactattc agttgaagat ttcaacttga acatcaaaga taaagaattt atcgttttcg
    10861 taggaccttc aggatgtggt aaatcaacta cactccgtat gattgctggt cttgaagaca
    10921 ttacagaagg tactgcatct atcgatggcg tggttgtcaa cgacgtagct ccaaaagacc
    10981 gtgatatcgc catggtattc caaaactacg ctctttaccc acacatgact gtttatgaca
    11041 acatggcttt cggtttgaaa ttgcgtaaat acagcaaaga agacattaac aaacgtgttc
    11101 aagaagcagc tgaaatactt ggattgaaag aattcttgga acgtaaacca gctgaccttt
    11161 caggtggtca acgtcaacgt gttgccatgg ggcgtgcgat tgtccgtgat gcgaaagtat
    11221 tcttgatgga cgaacctttg tcaaacttgg atgccaaact tcgtgtatca atgcgtgctg
    11281 aaatcgctaa aattcaccgt cgtatcggag ctacaactat ctatgtaact cacgaccaaa
    11341 cagaagcgat gacacttgca gaccgtatcg ttattatgtc agctactaag aaccctgctg
    11401 gtacaggtac tatcggacgt gtagaacaaa tcggcactcc tcaagaagtt tacaaaaatc
    11461 cagttaacaa attcgttgca ggattcatcg gaagcccagc tatgaacttc atcaacgtga
    11521 aattggttgg tagcgaaatt gtttctgacg gtttccgttt gaaagtgcca gaaggagcat
    11581 tgaaagttct tcgtgaaaaa ggctacgaag gaaaagaatt gatctttggt atccgtccag
    11641 aagacgtgaa tgcagaacct gctttccttg aaacattccc agactgtgtt gtaaaagcga
    11701 ctatctctgt atcagaactg cttggttcag aatctcacct ttactgccaa gttggtaaag
    11761 acgagtttgt tgcaaaagtt gatgctcgtg actacttgca aacaggtgca acagttgagc
    11821 ttggatttga cttgaacaaa gcacacttct tcgatgtaga aactgaaaaa acaatctact
    11881 aaaataaata aaattcaaag cactacaaga aaagatattt ctttatcaat tgtagtggag
    11941 agatatcagt taatctaggg agagaaacaa aatgcttctc tcctttttgc tagggaagtc
    12001 atattatgca tctatattgt gatgctcttt aatactcttc gaaaatctct tcaaaccacg
    12061 tcaacgtcgc cttgccgtac gtatgattac tgacttcgtc agttttatct gcaacctcaa
    12121 agctgtactt tgagcagttt acggctagtt tcctagtttg ctctttgatt tccattgagt
    12181 attatttgtg ggtaccatct acaagtgaag ctatatgcgt aaactacgtg agcaattgaa
    12241 ttcgaactag agaggtaata ataaatttat gctatagtta tggtgacttg tatgcttttg
    12301 attctagttt atcaaataat agattagaat tgtcagataa tatcattttg tgttataatg
    12361 aagaaaaaac agaggtgttc aaatgtcaga agcaggtcat aagtttttag caaaattggg
    12421 gaaaaaacgc ttacgtccag gtggaaagcg tgccacagat tggttaattg cagaaggagg
    12481 attttcaaaa gaaaagagaa tactagaggt tgcgtgtaat aggggaacta cagcaattga
    12541 gttggcacag cgttttggtt gcaagataac tgctgttgat atggatgctc aagctttaga
    12601 agtggctaaa aaatctgctg gaacggcagg tgttgctcat ttaatcagtt ttgaaagagc
    12661 aaatgcaatg aaacttcctt atcaagatgc tagttttgat attgttataa atgaagctat
    12721 gctgactatg caagccgatc aagctaagaa aaaatgtgta atggaatatc taagggtatt
    12781 aaaacctgga ggtcttctct tgacacatga tgtacttctt aaggaagcta aagagtctat
    12841 cagacaggaa ttatcacaag caattcatgt aaatgtaggt cctttaactc aagatggttg
    12901 ggaacaggtg atgatagaat caggttattg tgatgtgaaa gcattgactg gtgaaatgac
    12961 attaatgaaa ttatcgggta tgatttatga cgaaggtttg ctaggaactt tgaaaatttg
    13021 tgtaaatgct tgtaaaaagg agaatagaaa gcagttttta actatgtata aaatgtttgc
    13081 taagaataaa cagaaattgg gctttattgc gatggctagt tataaatcgt caaaacgtta
    13141 gataattatt gaagttaact tttccttttt tctttcttaa aaaatatgct ataatagaga
    13201 gtaaaaaact ttgaaagaaa gaaaaagatg aatttaaaag attacattgc aacaattgaa
    13261 aattatccaa aggaaggcat taccttccgt gatattagtc ctttgatggc tgatggaaat
    13321 gcttatagct acgctgttcg tgaaatcgtt cagtatgcta ctgacaagaa agtcgacatg
    13381 atcgtgggac ctgaagctcg tggatttatc gtgggttgtc cagttgcctt tgagttggga
    13441 attggttttg cgcctgttcg taagccaggt aaattgccac gcgaagttat ttctgctgac
    13501 tatgaaaaag agtacggtgt cgataccttg actatgcacg cggatgccat taagccaggt
    13561 caacgtgttc ttattgtaga tgaccttttg gcgacaggtg gaactgttaa ggcaactatc
    13621 gagatgattg aaaaacttgg tggtgttatg gcaggttgtg ccttccttgt tgaattggat
    13681 gaattgaacg gccgtgaaaa aattggtgac tacgactaca aagttcttat gcattattaa
    13741 tgaaaacagt ccctagggct gttttctcta cactaggata taaaaataga ctataactag
    13801 ttagagaaaa actataattg aaaactatat cttcttacag tataataaaa ggactaagtg
    13861 tttgagattt gtcttcaaac atatgcaatt attcctgaaa gagtacagtt aggagagggt
    13921 tatgccgatt cgaattgata aaaaattgcc agctgttgag attttacgga cagagaatat
    13981 ctttgtcatg gatgatcaac gtgctgccca ccaagatatc cgtcctttga agattttaat
    14041 tttaaatctc atgccacaga aaatggtcac agagacccag ttgttgcgcc acttggctaa
    14101 tacaccccta caactggata ttgattttct ctatatggag agccaccgtt ctaaaacaac
    14161 tcgttcagag cacatggaga ccttctataa aacttttcct gaagtcaagg atgagtattt
    14221 tgatgggatg atcatcacgg gtgctccagt tgagcattta ccatttgagg aagtggacta
    14281 ttgggaggaa tttagacaga tgcttgagtg gtctaagact catgtctatt cgacccttca
    14341 tatctgttgg ggggctcagg ctgggcttta tctgcgctat ggtgtagaaa aataccagat
    14401 ggacagtaag ctatcaggta tttatcctca ggacacccta aaagagggtc accttctatt
    14461 tagaggcttt gatgatagct atgtatcccc tcattcacgg cacacggaga tttctaagga
    14521 agaggtctta aacaagacca atctcgagat tttatcagaa ggacctcagg ttggggtttc
    14581 tattttggcc agtcgtgatt tacgagaaat ttatagtttt ggtcatttgg agtatgaccg
    14641 tgataccttg gcaaaagagt attttcgaga tcgtgatgca ggtttcgacc cacatattcc
    14701 agaaaattac tttaaagatg atgatgttaa tcaggtacct tgtctttgtt ggtcttcatc
    14761 tgcagccctc tttttcagta attgggtaaa ccatgcggtc tatcaggaga cgccttttga
    14821 ttggagaaag atagaagatg atgcatctgc atatgggtat ttataagagg aattatgaca
    14881 tatttagacg cttttaaatc aggtatcttg gttttaccga gtgccctgct cttgcatttt
    14941 aaggaactct ttccttctag cgacgatttt ctggtttggc aatttttcta tttgcaaaat
    15001 acgacaggct tagaagaaat gtcgccaagc cagattgctg aaaggattgg caaggaaatt
    15061 tcggatgtca accagtccat ttctaatctg acggaaaggg gactgctcca gtatcgtact
    15121 atcgaattaa atggcgaaat tgaattgctc tttgatgcta gtttggcctt ggaacgtttg
    15181 gatgacctgt ttggagcagt tcattcaagt tcagaccagc tgacacctca aaaccagctc
    15241 aaggatttgg tggaaacctt ccagcaggag ttgggacgat tgttgacgcc ttttgagatt
    15301 gaggatttga ccaagacact aaaggaagat ggaaccagtg ctgacttgat taaggaggct
    15361 cttcgtgaag ctgttttgaa tggaaaacca aactggaagt acattcaggc gattttgaga
    15421 aactggcgcc atgaaggaat caagagtgtg gctcaaattg aggccaagag agcagaaaga
    15481 gaagcaagca atcctcagtt gacacaggta tctgcagatt tcataaatgc catggatctc
    15541 tggaaggatt aatccatgca agtaggcttg aaatccgagt aagatttgca agctgtgtat
    15601 aattgtgata gaataaatag aaaataaatt gaaaaaagag gtatgtgaaa tgtcacgtaa
    15661 accatttatc gctggtaact ggaaaatgaa caaaaatcca gaagaagcta aagcattcgt
    15721 tgaagcagtt gcatcaaaac ttccttcatc agatctggtt gaagcaggta tcgctgctcc
    15781 agctcttgat ttgacaactg ttcttgctgt tgcaaaaggc tcgaacctta aagttgctgc
    15841 tcaaaactgc tattttgaaa atgcaggtgc tttcactggt gaaactagcc cacaagtttt
    15901 gaaagaaatc ggtactgact acgttgttat cggtcactca gaacgccgtg actacttcca
    15961 tgaaactgac gaagatatca acaaaaaagc aaaagcaatc tttgcgaacg gtatgcttcc
    16021 aatcatctgt tgtggtgaat cacttgaaac ttacgaagct ggtaaagctg ctgaattcgt
    16081 aggtgctcaa gtatctgctg cattggctgg attgactgct gaacaagttg ctgcctcagt
    16141 tatcgcttat gagccaatct gggctatcgg tactggtaaa tcagcttcac aagacgatgc
    16201 acaaaaaatg tgtaaagttg ttcgtgacgt tgtagctgct gactttggtc aagaagtcgc
    16261 agacaaagtt cgtgttcaat acggtggttc tgttaaacct gaaaatgttg cttcatacat
    16321 ggcttgccca gacgttgacg gtgcccttgt aggtggtgcg tcacttgaag ctgaaagctt
    16381 cttggctttg cttgactttg taaaataatc agtaagtagc aaaagctagg tggaacagca
    16441 ttcagatgtc tgttacattt tttataggag aggaaagatt gaaaacaaaa attggattag
    16501 caagtatctg tttactaggc ttggcaacta gtcatgtcgc tgcaaatgaa actgaagtag
    16561 caaaaacttc gcaggataca acgacagctt caagtagttc agagcaaaat cagtcttcta
    16621 ataaaacgca aacgagcaca gaagtacaga ctaatgctgc tgcccactgg gatggggatt
    16681 attatgtaaa ggatgatggc tctaaagctc aaagtgaatg gatttttgac aactactata
    16741 aggcctggtt ttatattaat tcagatggtc gttactcgca gaatgaatgg catggaaatt
    16801 actacctgaa atcaggtgga tatatggccc aaaacgagtg gatctatgac agtaattaca
    16861 agagttggtt ttatctcaag tcagatgggg cttatgctca tcaagaatgg caattgattg
    16921 gaaataagtg gtactacttc aagaagtggg gttacatggc taaaagccaa tggcaaggaa
    16981 gttatttctt gaatggtcaa ggagctatga tgcaaaatga atggctctat gatccagcct
    17041 attctgctta tttttatcta aaatccgatg gaacttatgc taaccaagag tggcaaaaag
    17101 tgggcggcaa atggtactat ttcaagaagt ggggctatat ggctcggaat gagtggcaag
    17161 gcaactacta tttgactgga agtggtgcta tggcgactga cgaagtgatt atggatggtg
    17221 ctcgctatat ctttgcggcc tctggtgagc tcaaagaaaa gaaagatttg aatgtcggct
    17281 gggttcacag agatggtaaa cgctatttct ttaataatag agaagaacaa gtgggaaccg
    17341 aacatgctaa gaaagtcatt gatattagtg agcacaatgg tcgtatcaat gattggaaaa
    17401 aggttattga tgagaacgag gtggatggtg tcattgttcg tctaggttat agcggtaaag
    17461 aagacaagga attggcgcat aacattaagg agttaaaccg tctgggaatt ccttatggtg
    17521 tctatctcta tacctatgct gaaaatgaga ccgatgctga gaatgacgct aaacagacca
    17581 ttgaacttat aaagaaatac aatatgaacc tgtcttaccc tatctattat gatgttgaga
    17641 actgggaata tgtaaataag agcaagagag ctccaagtga tacagacact tgggttaaaa
    17701 tcatcaacaa gtacatggac acgatgaagc aggcgggtta tcaaaatgtg tatgtctata
    17761 gctatcgtag tttattacag acgcgtttaa aacacccaga tattttaaaa catgtaaact
    17821 gggtagcggc ctatacgaat gctttagaat gggaaaaccc ttattattca ggagaaaaag
    17881 gttggcaata tacctcttct gaatacatga aaggaatcca agggcgcgta gatgtcagcg
    17941 tttggtatta agcgatgatt tgaaagaggg atgtgatagt agcaccctct ttttctttgt
    18001 tttatgatag ttcatcctcg agtaaattca agatcttgct cggaaatgaa gcttatatag
    18061 tagattgaat atagacaaag accttgtgat tggtaaaaca ttttagaaat tcatttacct
    18121 ttcctaatcg acttggtttc atcttatttc aatctattat agtattgggg aatttcttca
    18181 aaccacatca gcttggtcag ttctacctgc gacctcaaaa cttgtgcttt ggtcaagctg
    18241 ggtttagttt cctagtttgc tgatggattt ccattgacta taagcatcca accctctttt
    18301 ttgtcttcta aagaattctt aaattatcag tctattgcaa cttttctcat ataagttctt
    18361 tgtcttgcta ttagttttcc ttagtagtat actaaggtag taatcattaa gaagtggtta
    18421 caaaaaataa tgaatgaggt aaagaaaatg gtagaattga aaaaagaagc agtaaaagac
    18481 gtaacatcat tgacaaaagc agcgccagta gcattggcaa aaacaaagga agtcttgaac
    18541 caagctgttg ctgatttgta tgtagctcac gttgctttgc accaagtgca ctggtatatg
    18601 catggtcgtg gtttccttgt atggcatcca aaaatggatg agtacatgga agctcttgac
    18661 ggtcaattgg atgaaatcag cgaacgcttg attacactcg gtggaagccc attctctaca
    18721 ttgacagagt tccttcaaaa tagtgaaatc gaagaagaag ctagtgaata ccgtaatgtt
    18781 gaagaaagct tggaacgtgt tcttgttatc taccgttact tgtcagaact tttccaaaaa
    18841 ggtttggatg tcactgatga agaaggtgac gatgtgacaa acggtatctt tgcaggcgct
    18901 aaaactgaaa cagataaaac aatttggatg cttgcagccg aacttggaca agcacctggt
    18961 ttgtaagaaa taaggaaaca tagataaatc tgtaggaaat ttcttacaga ttttttctat
    19021 tttgtaagct attccaaacc agtctttttt tgagtttttt gataaaatag tactatcagt
    19081 gaaaaggatg gaagtatgac taagaaaatc gtagctattt gggcccagga tgaagagggt
    19141 gtgattggta aggaaaatcg tctgccttgg catttgccag cagaattgca gcactttaaa
    19201 gaaacaactc tgaatcatgc tatcttgatg gggcgtgtga cctttgatgg gatggggcgt
    19261 cgcttgcttc caaaacggga aaccttgatt ttgacgcgta atccggaaga aaagatagat
    19321 ggggttgcta cttttcagga cgtccagtct gttcttgact ggtatcaggc tcaagaaaag
    19381 aatctctaca ttcttggtgg gaagcaaatt tttcaggctt ttgaacctta ccttgatgaa
    19441 gtgattgtca ctcacattca tgctcgtgtg gaaggagata cctatttccc tgaagaactt
    19501 gacttgtctc tttttgagac agtttcaagc aaattttacg ccaaagatga gaagaatcct
    19561 tatgatttta ccatccaata ccgcaagaga aaggaactct aatggaacgg agtttatttg
    19621 gtctattcac ggcttttctg tgtttcatct gctttctggc aggagcacaa gcttttcgta
    19681 aaaagcgtta cgggctttct atcctccttt ggttaaatgc ctttaccaat ctggtcaata
    19741 gtattcatgc tttttacatg accttatttt agatagaatg acagtataga atggaaggaa
    19801 atcatgtcta caaatagaaa aaatgatatg atggtttatt gctcattttg tggcaaaaac
    19861 caagaagaag tacaaaaaat aattgctggc aacaatgctt ttatttgtaa tgaatgcgtg
    19921 gagttagctc aggaaatcat tcgagaagaa ttggttgagg aagtcttggc agacttgtct
    19981 gaggtgccaa aaccaattga actcctccat atcttgaacc actatgtaat tggtcaagat
    20041 cgtgccaagc gtgccttggc agtggcggtt tataaccact acaaacgcat caatttccac
    20101 gatacacgcg aagagtcaga agatgtagat ttgcagaagt caaacatttt gatgattggc
    20161 ccaactggtt cagggaaaac tttccttgcc cagaccttgg ctaagagctt gaatgtgcct
    20221 tttgctattg cggatgcgac agctctgacg gaggctggtt atgtgggtga ggatgtggaa
    20281 aatatcctcc tcaaactctt gcaggttgct gactttaaca tcgaacgtgc agagcgtggc
    20341 attatctatg tggatgaaat tgacaagatt gccaagaaga gtgagaatgt gtctatcaca
    20401 cgtgatgttt ctggtgaagg ggtgcaacaa gcccttctca agattatcga gggaactgtt
    20461 gctagcgtgc cgcctcaagg tggacgcaaa catccacaac aagagatgat tcaagtggat
    20521 acaaaaaata tcctcttcat cgtgggtggt gcttttgatg gtattgaaga aattgtcaaa
    20581 caacgtctgg gtgaaaaagt catcggattt ggtcaaaaca ataaggcgat tgatgaaaac
    20641 agctcatata tgcaagaaat catcgctgaa gacattcaaa aatttggtat tatccctgag
    20701 ttgattggac gcttgcctgt ttttgcggct cttgagcaat tgaccgttga tgacttggtt
    20761 cgcatcttga aagagccaag aaatgccttg gtgaaacaat accaaacctt gctttcttat
    20821 gatgatgttg agttggaatt tgacgacgaa gcccttcaag agattgctaa taaagcaatc
    20881 gaacggaaga caggggcgcg tggacttcgc tccatcatcg aagaaaccat gctagatgtt
    20941 atgtttgagg tgccgagtca ggaaaatgtg aaattggttc gcatcactaa agaaactgtc
    21001 gatggaacgg ataaaccgat cctagaaaca gcctagaggt gactatggaa cttaatatac
    21061 acaatgctga aatcttgctc agtgcagcta ataagtccca ctatccgcag gatgaactgc
    21121 cagagattgc cctagcaggg cgttcaaatg ttggtaaatc cagctttatc aacactatgt
    21181 tgaaccgtaa gaatctcgcc cgtacatcag gaaaacctgg taaaacccag ctcctgaact
    21241 tttttaacat tgatgacaag atgcgctttg tggatgtgcc tggttatggc tatgctcgtg
    21301 tttctaaaaa ggaacgtgaa aagtgggggt gcatgattga ggagtactta acgactcggg
    21361 aaaatctccg tgcggttgtc agtctagttg accttcgtca tgacccgtca gcagatgatg
    21421 tgcagatgta cgaatttctc aagtattatg agattccagt catcattgtg gcgaccaagg
    21481 cggacaagat tcctcgtggt aaatggaaca agcatgaatc agcaatcaaa aagaaattaa
    21541 actttgaccc aagtgacgat ttcatcctct tttcatctgt cagcaaggca gggatggatg
    21601 aggcttggga tgcaatctta gaaaaattgt gaggaaaaga aaatggcaaa aacaattcat
    21661 acagataagg ccccaaaggc tatcggaccc tatgttcaag gaaaaatcgt tggcaacctt
    21721 ttgtttgcta gcggtcaagt tcccctatcc cctgaaactg gggaaattgt aggagagaat
    21781 atccaagaac agacagagca agtcttgaaa aacatcggtg ctattttggc agaagcagga
    21841 acagactttg accatgttgt caaaacaact tgcttcttga gcgatatgaa cgactttgtt
    21901 ccttttaatg aggtttacca aacggccttc aaagaggaat tcccagctcg ttcagctgtg
    21961 gaggtagctc gtcttcctcg tgatgtaaaa gtcgaaattg aagtcatcgc agagattgga
    22021 taagctagtt gaagtttggt gttgccaaac ttcttttgat ataaggagaa aaagatgaca
    22081 aagaaacaac ttcacttggt gattgtgaca gggatgagtg gcgcagggaa aactgtagcc
    22141 attcagtcct tcgaggatct aggttatttc accattgata atatgccgcc agctctcttg
    22201 cctaagtttt tgcagctggt tgaaattaag gaagacaatc ctaagttggc cttggtagtg
    22261 gatatgcgta gccgttcttt cttttcagag attcaagctg ttttggatga gttggaaaat
    22321 caagatggtt tggatttcaa aatcctcttt ttggatgcgg ctgataagga attggtcgct
    22381 cgttacaagg aaaccagacg gagtcaccca ctagcagcag acggtcgtat tttagatgga
    22441 atcaagttgg aacgtgaact cttggcacct ttgaaaaata tgagccaaaa tgtggtggat
    22501 acgactgaac tcactccacg tgagctgcgc aaaacccttg cagagcagtt ttcagaccaa
    22561 gaacaagccc agtctttccg tatcgaagtc atgtctttcg gatttaagta tggaatcccg
    22621 attgatgcgg acttggtctt tgatgtccgt ttcttgccaa atccctatta tctaccagaa
    22681 ctgagaaacc aaacgggtgt ggatgaacct gtttatgatt atgtcatgaa ccatcctgag
    22741 tcagaagact tttatcaaca tttattggcc ttgattgagc cgattctgcc aagttaccaa
    22801 aaggaaggta agtccgtttt gaccattgcc atgggatgta cgggtggaca acaccgtagt
    22861 gtggcatttg ctaaacgctt ggcgcaggac ttatccaaga attggtctgt taatgaaggg
    22921 catcgcgaca aagaccgcag aaaggaaacg gtaaaccgtt catgagaaaa ccaaagataa
    22981 cggtgattgg tggagggact ggaattcccg tcattctaaa aagtctgcgg gaaaaagatg
    23041 tggaaatcgc agctatcgtg acggtggcag atgatggtgg ttcttcaggt gaactccgaa
    23101 aaaatatgca acagttgaca ccgccaggtg atcttcgtaa tgtccttgtg gccatgtcgg
    23161 atatgcctaa gttttatgag aaggtctttc agtatcggtt ctctgaggat gccggagcct
    23221 ttgctggcca tccattggga aatctcatca ttgctggctt gtcagaaatg cagggttcaa
    23281 cctataatgc catgcagtta ttgagcaaat ttttccatac aacagggaaa atttatcctt
    23341 ccagtgacca tcctttgacc cttcatgcag tctttcagga tgggacagaa gtggttggag
    23401 agagtcatat tgtagaccat cgaggcataa ttgacaatgt ctatgtgact aatgctctaa
    23461 acgatgatac gcctctggcc agccgtcgag tagtgcagac catccttgaa agtgacatga
    23521 ttgtcctagg gccaggttcc ctctttacct ctattttgcc caatatcgtg attaaggaaa
    23581 ttgggcgggc tcttttggaa accaaggcag aaattgccta tgtctgcaat attatgaccc
    23641 aacgtggaga gacggaacac tttacagata gcgaccacgt ggaagtcttg catcgtcacc
    23701 ttggtcgccc ttttatcgac actgtcttgg tgaatattga aaaagtgcct cagaaataca
    23761 tgaattccaa ccgttttgat gaatacttgg tgcaagtgga acacgatttt gtaggtcttt
    23821 gtaagcaagt ttcgcgcgtg atttcatcta acttccttcg tctggaaaat ggcggtgcct
    23881 tccacgatgg agatttgatt gtggacgagt tgatgcgcat tatacaggtg aaaaaatgag
    23941 tttcacagta gcagtaaaag aagaaatcct gggccaacac catctgagcc ggcatgaatt
    24001 atctgccatt atcaaaatgt ctggtagcat cggtctctcg acttcgggct tgactttgtc
    24061 agttgtgaca gaaaatgcca aactggcccg tcacctctat gagtcctttc tccatttcta
    24121 tgaaatcaaa tctgaaattc gtcaccacca acggagcaat cttcgcaaga atcgcgtcta
    24181 taccgttttt acagatgaaa aggtgcagga tttgttaagt gatttgcact tggcagactc
    24241 tttctttggc ttggaaacag gtattgatga ggcgatttta tcggatgagg aagcaggtcg
    24301 tgcctatctc tgtggcgctt tcttggcaaa tgggagcatt cgtgaccctg agtcaggcaa
    24361 gtaccagttg gaaatcagtt ctgtttatct ggaccacgcg caaggaattg cctcccttct
    24421 ccaacagttt ttactggatg ccaaggtgct tgagcgcaag aagggggctg tgacctatct
    24481 ccagcgagca gaagacatta tggacttctt gatagtaatc ggagccatgc aggcacgtga
    24541 tgattttgag cgggttaaga ttttgcgaga aactcgtaac gacctcaatc gggctaataa
    24601 tgccgagaca gctaatatcg ctcggacagt ttctgccagc atgaagacca ttaacaatat
    24661 cagtaaaatc aaagatatca tgggcttaga aaatttgcca gtagatttgc aggaagtggc
    24721 gcaactgagg attcagcacc cagactactc tatccagcag ttagcagata gcctcagcac
    24781 ccctctgacc aaaagtggtg tcaatcacag actcagaaaa atcaataaga tagccgatga
    24841 attataacga tataaagaaa ccccttgaat tatcaacatc ttcaaggggt tttgttgtgt
    24901 tatgaaatca aaaaggggca accaaggggc agaattaaaa aatagtatct aatttattga
    24961 ccagtttatc ctccatatcc tcagtagtat gagaatagat ttccaaagtc atttttgcat
    25021 ttgagtgccc aactcgatcc attattgatt ttattgggag gccagactct gctaaaaacg
    25081 aaatatgaga atgcctaaaa atatggctag ataagttttt ttctattttg gcctgttttc
    25141 catatttttt taatatctgt atgaagcaag ctattgttgt aggttgattc catttttcaa
    25201 aacagaaaat ataatcatcg cttgacaatg gctggaaacg ttcgctaagt cgtactattt
    25261 gtctttgaat agcttctatg acactctctg atactttgat tgtccgtatt gaatttgtag
    25321 tctttggtag cgtcttgatt ttgtttactg aatcaaaatt acctgtgatc tcaattttgt
    25381 tgttttcgaa gtctatattc ttcagttgta aggcagttaa ctcaccatat ctcataccag
    25441 ttaatgtcag cacaagaacc atatcagcgt acttttggtg atattctcga cgattaagga
    25501 catcgacaag tgcttttatt tcttgcatgg tgagaaagtt gttacgcttt ttttccagtt
    25561 cttctaaagt ctttggtttt tgaggaattg tagtataatc gacctcgttg ttttcaatgt
    25621 aagagtattg aacagcgtaa ttaaagatac ctctgagcct atgccgtact tttttagctg
    25681 taatatatcc gttgctttca ataatttttt caatagcctc ttgaagaaaa cgcctgtcaa
    25741 gattagcaag tatggtatcg gattgtatga cttccttcat cttcttatca actgatttac
    25801 aattatgttt tgttgattcc tttactgttt gcgcccatga tttatagaaa aggttataga
    25861 tttcttcaaa tgtaatgctt tctacttgtt ttgtgctgag ttttttattt atcttctctt
    25921 gtaacaagat agcagcttga tttcttgcct ggggagtttt cttctccatg gttactgaaa
    25981 ctttttttaa tttctcagta tatggatctt tatatcgctc aaaatattta aatttgccat
    26041 ttggcaattc ttccatccac attgcgttta cctcactttt ttgttaaaat gggtacaaga
    26101 aaactacctt tttaatggtt gtttcctata catgatttcc tcacactctc cttggccaaa
    26161 atttgagtgt ggggattttt tggttgctat ctcgtcagat aataaaataa ggtgtacctc
    26221 ttagaagtac accagacgat tttatccttg acgaacaagg cttttttaca ttcttagtgt
    26281 atttcttttt taaatttctg tcaagcagtt atttcctaaa tggaaatagt tggttttaat
    26341 ttatactttt ggttcattac ggtgccaatc attaggaaaa cctaaagact ggttgattac
    26401 attgatgtct atagaaggca gctttttctc tagtttgata actttttttc taagagtatt
    26461 ccacaaaatg ttgaatgctg ctttactaat aaagcattga aggctaataa ttgttgaata
    26521 tacagttttt ctactgtcat ctcccatcaa gatctctttg ttatgaatcg tttcccaaaa
    26581 cgtactatta gaacggcatc tgaagtttaa taagcgatta ttgtgagcgc atttgtttcg
    26641 tacctcgtta atatttttta gaaaagatat caaggtttct ggtgggaaaa catcgttaaa
    26701 gtcaggtatg tttgtgctta taaaacttac taaatcccgt gcgatttcat tttggagtga
    26761 attaggcagg ttttcaataa tcgtgcgtaa atctccaaac tctagataat cagttagtac
    26821 ccagattggg acatctgaat gagtatgtgc gtagtggtga attgaatttc ctctgtatcg
    26881 cttgtttgtg tttatgattt tggatagttt tgatacaata aatcccacgt ctaatatttt
    26941 attatctgca taagaattgg tgtttaaata agcgtatttt tgactggggt aagcttcggc
    27001 gaatctgtga gcagtgattg acttgatatg gtgttcagct tcaagaatag cttgcaaaat
    27061 ggctcgtttt acatctttgt caaatgtata gagacttgaa acttcgtcaa atgtgacgcc
    27121 gtcaatataa gtgtcagtac cagggtgttg aaaaaactta ctgtatccat tgataatatt
    27181 gtagtaattg ttacttagca ggtacttagc tgctttagat tcatctgtaa tggataaccc
    27241 tctgattttt agtgttgcga tttgttcctc gattgtttta aatggcttca aaaaaactcc
    27301 cccattctaa tttagaatga aggagtttcc ccgtatcggt ccccgtagag atcccgacgc
    27361 tttttctcta atgaattcat tctaaatgat ttttttaaaa aagtcaactg ttttttaata
    27421 tttttaaaaa ataatttttt tattcccctc tatacacccc gactactgca taaatcttga
    27481 tgtgtgtgtc ttcggctggt gggaagtcta ggatgatgtc ttcgtacttg tcattgagtg
    27541 acactaggcg taagcgtccg ttttcggtat atatcttctt gaagtaagaa cggtctccat
    27601 atgcgataac tgctaaatct ccgttgtagg tagtcagtcc tttgtctact aaatagagaa
    27661 tgtctccgtc ttggtagtcg ggttgcatgg agtctccact gaccttggtc gcaatatcgt
    27721 ggcgtggtgg tcgctcgtca acctctatag tctctctgtc tgtatcgtcg tacccaaatc
    27781 catagttaaa tccagaagct gctgccgtct cagatacaac ctcaacttgg tacaagctga
    27841 taacttccga tacttcgttt atcttcgttt cttcttcgtt ttggctctcc agaagctcct
    27901 cagaggtccg tagcacgatt ttttgattgg gtggggttaa ttgcactacc ttatccatta
    27961 tctgctgtgt gagcgaatct ggagcgtctg gcagtgagtt ggtggattct tctttaaaag
    28021 tagtatctat atctgatttt ttaacaccga aataatcagc cagtttttgg ataacaccaa
    28081 aagaaggagc gcttcttaac ttcatatagt ctgtcatagt acttgctgta attccaactt
    28141 ctttagccaa ctctttttgg gtgatgccac gttgctttct aaagtgtgta atattttcag
    28201 caataatttg cattcgtttt ttttcgtcca tttacgatta cctcgtattt tttataatta
    28261 cattatatat catttttgaa tgataaacaa tcaaaaatac gaaaaaatcc tatttttttg
    28321 ataaaaacta ttgacaatac gaaaaaatcg tattataatt aaatcaagct taaggaaaag
    28381 gaggtaaggc aaatgaacga actagaaaga acagccctca atgagatatt gaggactgtg
    28441 acatatatag ctgagaagtt ggatgaagta gattctaaga tttctttgaa cgattcacaa
    28501 gctcttgagc atcaaggaaa ttgagtttca tttccatgta gtgaataact ccgtgtaggt
    28561 agttctttag gtctgtaaaa cctttatcag gattatttct atagtaatga ccttcgtcgt
    28621 taccgatata agcagatgca agcgcaaatg ttttaaggtc ttcatccttg atatattttt
    28681 caataacttg ttttaatgac attttaatga ttttatcttc atcatcagga tttgtaacaa
    28741 tggagaaatc tttaacaaag aactcaagcg ccttacggta tccaatacct gcaatgtggt
    28801 ctagttgttc gtgttcagct ttcagtgctt ggacatagat ttgcttacca attggagaaa
    28861 ctatctctac atcgtcagat ataggtatat cgctcggaag attagggatt actttgatat
    28921 gttcaatttc gtatttttcg gtatagtcat tgattaaaaa tcttgtagct ataaactcct
    28981 ctgtccaaaa gtgcttacaa cctaagcatc tacatgttaa tactaagctt gttttatttt
    29041 ctccaagaga aaaataagaa gagttcacaa gatctggatt ggttggtttt ttacaatttg
    29101 ggcaaatgtc ttcaacggtt acaggcctag aaacagaaga atttactttc actcgaaata
    29161 tcataagatt tctccaatcg ttttattttg attataccat atttgaaagg gggtgaggaa
    29221 atgagaccaa gacgatatcc gtatagtggg aaaaaagagt ccaccttcgt aaaggcagac
    29281 cctgagttaa tgttgaatat caataagatt gatgttggaa atatacaagc gaaaaatata
    29341 tttggaaaaa tttaaggagt aggaggatgg atgaaagaaa atatagaaca tcttcatgaa
    29401 cgcataaagc attttcagtc attgattgct tatatgtctg agcatgagaa aaagtattat
    29461 ttagaaaaag attggttcga taacccaacc ctaatttcta tagaagacgc aaaaaaagaa
    29521 gtagaactac tttaacagaa aggaggtagg aacgtgcagt ggactttaga agctatgaga
    29581 atcaacaaag gacttactca agcagagttg gcagaaaaat ttgaagtttc aagtcaaaca
    29641 attgctagat tagaaaaaga tagctctgat atcggttatc agctattgaa aaaatacatg
    29701 ttttttttca atgtgaaatt cgatgatatt tttttaggga aaaaatacga aaatttcgta
    29761 aataactaga aacaaaaaaa taagaaggag gaacacatag atggaaagcg ttcttgaaag
    29821 cttgaaacaa gaaaaagacc acctcgaaaa aatcattaag gtagttacct ctggtggtaa
    29881 atttctgaga ttgccgtatc aaaaaaagtc acgctcgatt agtgagaatc tgaaattgat
    29941 ttctcaaaat cttgataaat tgagcgagca agttcaacaa accacgaatc agcattcatg
    30001 atttcaagat gacgaaagaa acctgttttg atttccagtt tgatatcatg ttacagcgac
    30061 tcgataaagc gattagtgat taaatttttg agatgtaagt ttttttcatg tcaaactttt
    30121 tcatgtcaaa ttttttacac taataaatat taactaacaa caagtattaa aagacaacca
    30181 gtcctacttc tctaaataaa agagagggta gaaaaaataa atacaaagga ggtgaggaaa
    30241 tgagaccaag acgatatccg tatagtggga aaaaagagtc cacctttgta aaggcagacc
    30301 ctgagttagt tgaaaaactt ttaagaaaca ctagttttct tgagcgttta caaaaaaaag
    30361 cctatcaatt ttcagataga ctcagaagaa tttaagcgtc ttagctatga agccattcat
    30421 gatacttctc aagtaactca atagtagtta ttacagaagt caaaccactg accttcccca
    30481 gttgcaatcc gtctgtatgg tcaatctgtt tagtagcttc attagcttta gcagagatag
    30541 cttgcatatc ttcagctgtt aaagattctc gaaaatcttt aaaggatttc ataaaaactc
    30601 ctcctttcta ttggaatttt gactaaaacg gtgagaggtc ctagtcgaga ttattatagc
    30661 aatttaggag gatattacat cggtcttgag gctgattttt ggaggcaata ttggaagata
    30721 aaatcataga acttgctgat tacttcatca gcgaatctac aacgtacaga gaagcaaaaa
    30781 tagcgtgtga gaagctattg aaacaagtca gccacgagat tgaactcagg gcgatggaaa
    30841 gtaggacagt atgaaagaag cagtaaagga atttctaaaa ttcaggagcc gatttacaaa
    30901 aatagaatgg tttgaaatca accaagctgt cgaagctcgt ttaaatcaaa aagccgacca
    30961 gttgaaactg gacgacgtag atttagaaat catttctagc agactagaaa aagttatcta
    31021 gaaacgattt gaatgaacat tggatggata cgatagtcag cgccacgata gtgaatgtag
    31081 atataatcct gatggtacat cgagtttgct tcaggtttag aaattggtga gtagagttct
    31141 gcattttctt cccaccaaat gtaaggacta gccatatttg gtcccattac acaatcgtcg
    31201 tcggctgata ggttcaccca atttccgcaa agacatgcgt gaatttcagt cataatatta
    31261 cctcctttct ggtttcatta tagcagaaaa ggagatagca aaaaagcacc tgacggaaat
    31321 caggcgcata cttaaatatt caacatgatt ataacacgaa aggagcaaaa atggaagcag
    31381 ttgaaattgt aagaattaaa gatgtgatta ttgaaaaagt ctctgctaat gatgaagagt
    31441 taaaacgtat ctttggatgt tcaaaacgac aagcaggaga gcgaagaaga gaaatgcaaa
    31501 aactccctag tcagcaaaaa catcttttgg atagtggaca acttgtaacg attaaaggtt
    31561 tctatgaata cttgcaatat cgtggaacta aagcttggaa aaaagaaatg gaaacaagca
    31621 agaaaatgag gtcagcagga tgaacctact atcaagaatc aaaaactatt tttcggaaga
    31681 ggtcaaagaa actaatctcg actggaaaga ggtcgcttta gacctcaatc aatcactaat
    31741 tgaaacacag gaaaaacttc aagaagcgaa tcaagaaatc gcagacttga agaaaatcgt
    31801 agcaatctat aaagaaaagg agaaagaaaa acgatggaat atatttacct ggtaacaatc
    31861 gtaggaattg gactatggtc gctagtaaat aaactagatg accacgctga aatgaaacaa
    31921 aaagagcgcc agctgatggc aaacaatgtc gcacggatga atctgagaaa ttcagataag
    31981 caatttactt atgatgtaga accgcctgaa gggttgaaat aaggaggaga aacatgactc
    32041 aagctgaacg aattagggaa tattatagag agcaccctgc tgcctcatat gatgaagtgg
    32101 ctgaggtcgt tggtacaaca aatagtaatg tgagagcgaa cctggccaaa gacatcgtcg
    32161 attgctgaca aaggagcaac atgattatct tgtattgatc caaaaaaata agatttctcg
    32221 taatgtcgca aatgaaatga accaaaaatt tggcttatcg ctaactgaga aacagattaa
    32281 gagttatcgg agaaataata atctacatag tggtttgaca ggaagattcg agaaaggtca
    32341 gactcctcac aataagggga agaagtaccc caatatgcca aaaaacggcg ggcagttcaa
    32401 aaaaggtaat cgacctccga attatgtacc tgtcggtact atcaactaca caacaaacgg
    32461 ttatccaaaa gaaaagattg gagaacctaa tcaatgggtt ttgaaacacc gcaaggtttg
    32521 ggaggaccat cacgggctga taccaaaagg gtactcaatc gtttttctgg acggtgataa
    32581 aacaaactat gatatttcaa atctggcatg tttatctaag aacgaaattg ctagaatgaa
    32641 tcaaaatcat ttattcacgt ccaacgctga tttgactaaa tcaggtattg gactaacaaa
    32701 acttacaaat aaaatcagag aggtagaaaa aaatggctag tttatacgaa ctaacaggtc
    32761 agttcctgac aatttaccaa ttggatatcg atgacgaaac aaaagcagac acgcttgagg
    32821 ccatcgattg gcaagaacaa tttgaacaga aagcagaagg atatgcctat gttatcaaga
    32881 atctagaagc cgacgtggca atgtacaagg ctgaggaaga gagcttcaaa gccaagaaac
    32941 aggtggcaca gaaaaagctg gattatgtca aggataacat tatggcagct atgaatgtca
    33001 cggggcaaac cgaagttaag agtggtgccc tgattataaa aattgctaag aatccagaat
    33061 cagtcaaggt caacgaagac gaccttccga aaaaatattt tacaaaaaaa gtgacgcttg
    33121 cgccggacaa aaaaacactc aaagagttgc ttaaatctgg caagaaagtc aaaggtgcgg
    33181 agcttgtccg gacagaaaag ttggtgatta agtaatggaa ttgatgaata aaacacgagt
    33241 aacagattca ctagcagttg tgattggacc agaatcgatt gaagtacttg ttactgaagg
    33301 ttttctattt gatgttgcga ttcgttttgt aaaagtagac gaaacaaatc ttgatcaagg
    33361 aaatgaaaag ccagtattca ctccggaata caagctggtc acagttgcta aatacaagga
    33421 aaaacctatc tttgaatcgg aggaagatat tcgaaaattt gagaagcaag caaaagaagt
    33481 taaatcgcta tttgcctttg caaaggtaaa taaacaaaat tggtttaaca ctgcccttta
    33541 tccaggagtg ctgactgaga aagttggtgt ttgatgaaaa ttttagctat tgatccaagc
    33601 agtaataaaa ttgaaaccag cacaacagga gttgtcttgt tggataatgc aagattagtt
    33661 gatagctggg ttgtctctta tggtatgaga ggtttcgctg attggtttca cgaaatcgga
    33721 acaaatcttg aattcgatgt agttattgtt gaagaattta aggcgaggga taacgacaag
    33781 tcgaaagata atagcgtggc agaaaccatc gcctatatcc aactttgcta tccaggtgcc
    33841 attcttcaat tcaatgcagg ttacaagtcg gatattccaa acgatctttt gaaaatctta
    33901 gacctttgga aatttgaaaa aagtcatcat caagatattc gagcagcagc aagacttgga
    33961 ttattttggg caatgagaaa tgatattgaa gaagtggttc atgatatcgg aaaggtggtg
    34021 agtgagtatc acaataacgc taagaaagtg gcaagctgaa gcgattaaaa gaagtgaaca
    34081 tttatctaat ggaatctttt tagaggctct tgggggcaga ggcaaaacta tctgtgcact
    34141 tgctattgca aaacataaaa aagctaaaaa aatcatcatc acaaacaatc gactagctat
    34201 tctgaatggt tggatagatg cagtcaagtt tatgaatttt gataaaggtg ttgagattat
    34261 cattcagaca gatagatatc ttcaaaatca agtcaaaaag gggcataaat tagattgtga
    34321 tgtgctgata gtagacgaat ggcagaatat gtcttctgac aaacaagtgg ccttatatcg
    34381 caaaataaag cgaaaataca cgataggtct ttcagcgaca ccaattcgga aaaaaggaca
    34441 aaatttctat ccgcttgaaa aaacggtatt tggttgggca accccaaata ataaatttga
    34501 ctggcaaaag actcatggaa aaatggtcta tgatccattt agctattcaa aagagaagtg
    34561 ggaagatttt caaaattatg aaagttatat ctcgagcttg cctaatttct tccgctggga
    34621 agacattgaa aagattgaga atgccactga aaataacggt tttgaaacca agttctaccc
    34681 agtcacagtt aaagctggaa accctgagaa attagctgag tttaggcagc ttaacttggt
    34741 cactgttgga gacaagacgg ctatggccaa acagtccttt ggtcgcaaga cctttgaacg
    34801 gtacctaaat caaactggtg tgatcgttga ttttccaaag ttgaaaccag ttaacgctga
    34861 tacccctctc atgctcaaat tggacggatt gattgaaaga gcaccacacg atatgttgat
    34921 tgtcagtaaa tctaagcaga ttgtcaacgt cattagcgag cgccatcctg aaattggaat
    34981 ctggacgggc gatattcaag aaggacttta taagaaattc gtggttgcta ctagtcaagt
    35041 gttaggtgtc ggagtagacg gcttgcaaca caaataccaa actattgtcg tattggatcc
    35101 agtagaagaa ggttctggag aatatgatga ttatcgacaa ttgctctggc gcataacagg
    35161 aagtcgtcag cagcatgatg taaatgtaat tgaattttat tataaagaaa gttaaaaaaa
    35221 agaggaaaac aaaatgaata aaacaactga aatgatcgta tttcgtagcc gtaaaactgg
    35281 agaatttctt aattcttaca aggacagaag ttctttagca tttgcagctg acttttgcag
    35341 cttggaatat tgtttgaagc ttcctcgtaa aaaatacgaa gacaacaaaa agacttacaa
    35401 ggctcttgct gcagcttttg actatgaaat tgtcgcagtt gaagcggaat acaaattgac
    35461 ctatccgaat ggatcagaag ttgaacctat caagcgtgac cgttcatcaa ttgaggacat
    35521 gattaaggat attattggag gggttctcta atggcattta cacttccagc aaataaacca
    35581 caagttccta aagatacccc acgaaatttt ttcatctacg gtgaaaccat gagcggaaag
    35641 tcttatcttg caaatgaatt cccaaatcca atcgttttga acacagacgg gaatgcagaa
    35701 gctaacactg ttccaagcat tcagctgatc aatgaaaaag atgacaaggg acgaattacc
    35761 aattcagtaa ttaagcagct tggagatatc ttgcttgctc tccagacaca gaagcactct
    35821 tatgaaacag tcgttattga tgtaattgac gatgttattg aaatgattaa gattgcagtt
    35881 tgtgatgaat taaccccagt tggtaaacct cgcttgaaat ccttgtcgga aattccatac
    35941 ggcaaaggat acgacttctt taaccaagct atcacagaat tagtcattga cctcaaagca
    36001 ttgccaatga atgttattta catcagccgt caggtatctg aatatgatga caatggcaat
    36061 gccaccaaag acaagccaag cttgaaagat aagtatgtca atcttatcaa tggaaactct
    36121 gatttgatga tccacactga aaaactcggc aacaactaca accgtgaggt tgaccgcaag
    36181 cgtaagacct attatgcgga ccaggttgat gacaaggcca tcttgaaaat cttggcaact
    36241 atccgtgggg ctgttgagcc tgcaaagggc aagctagccc ctaaaaaaga agcagctaag
    36301 acaactaaac cagctaagac cgaaaaaaca aaagaggcac ctaagaaaga agttgactct
    36361 gatgatgaac tattttaaga aataaaggag aatacacatg agcttactag atatcgcaaa
    36421 atcaatcaaa aaagagggct ttgacccacg caaagacagc gccaacggtc ctgcaccaat
    36481 cccagctggt acttatccag tagtcctgaa gaaagcaacc ttcaacgtat cggacaaagg
    36541 ctgggaaagc cttggttatc aatttgaaat ccgtggcggt gattacagtg gacgctctga
    36601 atttgcaaca tttggcacac tgactgaatg gaacggtaag aaccttgact gggcagttga
    36661 acgcactatg aaattcttta tcaaagcctt ggtccttgct ggcgacagta tgcaaggaaa
    36721 tgaagaagac ggtaaagcct tggaagaggc tctaaaacgt aaggcagttg gctcttacta
    36781 caaccttgtt atctctgtga ctaaggggaa agatggccgt gagttccgaa actatgacct
    36841 tgaagaagaa gcacaaccgc tgactgaagc tgatattgat gacgatgacc tcccttttta
    36901 agaaataaca agttctgggt cattgatgaa actgatgagg aatttggtcc tttcacgaca
    36961 gtagaagagg cttatacagc tatgctaaca tacttggata tgactgaaga tgaatatcaa
    37021 tcaaattata tggcccaaga acttgtttat atttacaaag aggagaagta atcatgccgt
    37081 cgatgaaaga atacgcatta cagtatcaaa aattagggtt ctcagtcatt ccaatcaatc
    37141 ctaaaaacaa gatgcctttg attaattttg ctgataagcc agccatgact ccatctgaga
    37201 ttgaaaactt ttgggacggc taccctaatg caaacattgc cctaaagact accaacttct
    37261 ttgtcattga tattgacaaa cacggcaaat cgaacggttt taaatcgcta aaaaaatgga
    37321 aacatctaaa tttaatcgaa ccgacactgc aagctaagac ggctagtggc ggtaaacatc
    37381 tattctactt caaacgagaa gatgagccga tcactcagat gattggattc ttgcctggtg
    37441 ttgatattaa ggctcacgaa aataattatg tgttagtcgc accctctgcc acagataaag
    37501 ggcagtatga gtgggatctg gaaaagtcta aggaaggtgg cacgatggtc actccttcaa
    37561 aatatttaat ccagtctata aaaaaacagt atggcgaaac tcacggttat aagtatgatg
    37621 gtaaggacgg tcttagggat ttagttagac gttcacatac tagagaccga acacagacta
    37681 cagatctctt tgaaaccatc gcccttggtt ttggtgatga aggtggacga aatgacaaac
    37741 tagcaaaatt cgtaggtggt ctcttatatc gtgcggtcga cgatggtgta gttgttcaac
    37801 ttgcaagatt agcaaatgca aatagtccaa cccctttgcc tgaaaaggaa atgatgcgta
    37861 ctattgaaag tatgattaaa aaagatagga ggtgattgtg attggtaatg tagtaagtat
    37921 tgactcacaa cctaagatga taacgactgc caagggagac atcaaggcca acagtccaag
    37981 taatgtgttg atgtctttca aagctgatga tcagttgagt atttacctaa agcacaacga
    38041 tttttcccaa gagcatgaac tccttaaaga tatcaagatc ggcaacactc tttttaaaaa
    38101 aggtgagctc ccttctaact ttgattcagt cgtaaaagtt tactttgaaa gtgtgttagg
    38161 tgttgctttc tctagccagg cgatgctgga cggcatggaa acttttttct cagaacgttc
    38221 ttacaatcca gtcattgagt atatggaaaa ggctgctgaa aaatgggatg gtcgtaaacg
    38281 aattgaccga atgcttcagg tttacctggg ggctgaagat atccctttag tttctaaaat
    38341 cgctcaaatg tggctagttg gtgcagttgc taaagtttat gatccatacg ttaagtttga
    38401 ctatgttctg gatctagtcg gtggacaagg agttgggaaa acatccctcc ttcaaaaatt
    38461 gggtggcgaa tggtatacgg atgccgtaac agatttctct aataaagata attacgacat
    38521 tatgttaaag agtctaatcg tcaacgatga cgaaatggtg gccagtaatc ggatgagctt
    38581 tgcagaaact aaggccttta tttctaaaac tagcctacgt tatcgtaaac catacatgaa
    38641 acgcacagaa gagtttgcca aaaacttcat tttagctaga actactaacc aaacagaata
    38701 cctcaaggac aaaaccggtg aacgtcgttt tctaccagtt atggcagata gtaaacggca
    38761 aaaaaaacat ccaatggaaa tcgagccaga gacaattgaa caaatctggg gcgaagccgt
    38821 tacaatctat cgtgctggtg ctgatttgat gtttgatgaa aatacagagg atgaactgaa
    38881 tatctaccgt gaacagttca tgtatcgtga tgaagttgaa ttacaagtgc ttgaatatct
    38941 tgatatgccc gtccctgaaa attggcaaaa ctggtctatt cagcaacaac atcaatacac
    39001 aagtaaatat ttcgataata gtagcgactt tgatcctgga agcaaaaaac tagataaggt
    39061 ctcaactcgt gaaatgatgt acaacttatt tatgagaaat tcgaatgaca ggaagctgtc
    39121 aacgaagatt aacatgatca tggataatca tcctgattgg aaaaaaagtg ttttccgggc
    39181 aggaggtaaa agtacaaaag ggttcgtaag agtgaaagat tcggaaaaaa ctaatcggta
    39241 gcaattaaaa aattatcggt agtcatcggt agcagttgag ggggagatcg gtagcattct
    39301 accgataaaa taggacatcg gtagcacatc ggtagcagtc taaccccttg atattactga
    39361 cttttattta atatttatat ataatgctac tcttctacct atatttttaa aaaaagtata
    39421 taaaataata gtaataataa agaaagctta tagaataggg attcttgaaa aaaacttttt
    39481 actttttaga atttatcggt agcacggtag cagtttagaa aaaagaggta aaaatgtcat
    39541 acacagtaac attatttttt gacaacatgg tagacgaaac tcactttttt aagaaagaga
    39601 gtgatgctgc caaatgcaag gctcagttag aaagcaagta tcgagggaat cgaatgtata
    39661 aagttaagca ggagaaattg gaagaatgaa taagcaggaa ctgattaaac gtatcgagga
    39721 tttgccttat acagaggggc ctatcgcaga tacaatcgaa attaatagaa attggatatt
    39781 gaaatcaatt gaacagctag ccgaatccga aataggtcac gcagatgaag ctccacgcta
    39841 cgtaaagaac atactagcac gattgcgaga attgccattg catgatagag agttttggtt
    39901 aaaggctatc atgagcgaat ttgaacagga ttttagccat gcaaaatggc gagagggcta
    39961 cgagcaaggt aaaattgagg gtatggttga acg
//
LOCUS       DAVBOD010000014        39042 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 640-05
            SAMEA1012484-rid20186543.denovo.014, whole genome shotgun sequence.
ACCESSION   DAVBOD010000014 DAVBOD010000000
VERSION     DAVBOD010000014.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012484
            Sequence Read Archive: ERR059358
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 39042)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 39042)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979948.1
            Genome Coverage       :: 595x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:03:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,266
            CDSs (total)                      :: 2,219
            Genes (coding)                    :: 2,091
            CDSs (with protein)               :: 2,091
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 71 of 128
            Pseudo Genes (incomplete)         :: 50 of 128
            Pseudo Genes (internal stop)      :: 33 of 128
            Pseudo Genes (multiple problems)  :: 22 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..39042
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012484-rid20186543.denovo.014"
                     /strain="NIG 640-05"
                     /db_xref="taxon:1313"
     gene            complement(1..208)
                     /locus_tag="VQ862_000801"
                     /pseudo
     CDS             complement(1..208)
                     /locus_tag="VQ862_000801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
     gene            complement(270..719)
                     /locus_tag="VQ862_000802"
     CDS             complement(270..719)
                     /locus_tag="VQ862_000802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HET3115174.1"
                     /translation="MTLTTFLLQAVASFLAIITFLIVLNVQRSMLLPGGILGMTVWLI
                     YLLLKEPTNVIVATFIAAIIGSCVSQILSILYKTPAVVFILAILAPLVPGYLSYRTTA
                     FFVTGDYNKALASATLVVMLALVISIGMASGTVILRLYHYIKTHRVS"
     gene            complement(721..1479)
                     /locus_tag="VQ862_000803"
     CDS             complement(721..1479)
                     /locus_tag="VQ862_000803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HET3115175.1"
                     /translation="MEESKELNAVIDVIMLAGTILLKSGSEIHRVEDTMIRIAHSQGI
                     VDCNVLAMPAAIFFSIENTNISRMKRVTSSSYNIEKVCDVNQISRQLVGGQIDLETAF
                     KQLTALQAQPLPYTKLQVTLAATFSAPFFSVMFSGNIYDALGAGVATLFGFAFSLYVE
                     KFIRIPFVTAFAGAFVFGIIAQFWARYTGFPSTADLIIAGAVMPFVPGIALTNAVRDI
                     MTNHINSGMSKMFESLLITLALGAGTSVALVLVN"
     gene            complement(1594..3573)
                     /gene="pknB"
                     /locus_tag="VQ862_000804"
     CDS             complement(1594..3573)
                     /gene="pknB"
                     /locus_tag="VQ862_000804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stk1 family PASTA domain-containing Ser/Thr
                     kinase"
                     /protein_id="HET3115176.1"
                     /translation="MIQIGKIFAGRYRIVKQIGRGGMADVYLAKDLILDGEEVAVKVL
                     RTNYQTDPIAVARFQREARAMADLDHPHIVRITDIGEEDGQQYLAMEYVAGLDLKRYI
                     KEHYPLSNEEAVRIMGQILLAMRLAHTRGIVHRDLKPQNILLTPDGTAKVTDFGIAVA
                     FAETSLTQTNSMLGSVHYLSPEQARGSKATVQSDIYAMGIIFYEMLTGHIPYDGDSAV
                     TIALQHFQKPLPSVIAENPSVPQALENVIIKATAKKLTNRYRSVSEMYVDLSSSLSYN
                     RRNESKLIFDETSKADTKTLPKVSQSTLTSIPKVQAQTEHKSIKNPSQAVTEETYQPQ
                     APKKHRFKMRYLILLASLVLVAASLIWILSRTPATIAIPDVAGQTVAEAKATLKKANF
                     EIGEEKTEASEKVEEGRIIRTDPGAGTGRKEGTKINLVVSSGKQSFQISNYVGRKSSD
                     VIAELKEKKVPDNLIKIEEEESNESEAGTVLKQSLPEGTTYDLSKATQIVLTVAKKAT
                     TIQLGNYIGRNSTEVISELKQKKVPENLIKIEEEESSESEPGTIMKQSPGAGTTYDVS
                     KPTQIVLTVAKKVTSVAMPSYIGSSLEFTKNNLIQIVGIKEANIEVVEVTTAPAGSAE
                     GMVVEQSPRAGEKVDLNKTRVKISIYKPKTTSATP"
     gene            complement(3570..4310)
                     /locus_tag="VQ862_000805"
     CDS             complement(3570..4310)
                     /locus_tag="VQ862_000805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stp1/IreP family PP2C-type Ser/Thr phosphatase"
                     /protein_id="HET3115177.1"
                     /translation="MEISLLTDVGQKRTNNQDYVNHYVNRAGRTMIILADGMGGHRAG
                     NIASEMAVTDLGVAWVDTQIDTVNEVREWFAHYLEIENQKIHQLGQDEAYRGMGTTLE
                     VLAIIDNQAIYAHIGDSRIGLIRGEEYHQLTSDHSLVNELLKAGQLTPEEAEAHPQKN
                     IITQSIGQKDEIQPDFGTVILESGDYLLLNSDGLTNMISGSEIRDIVTSDIPLADKTE
                     TLVRFANNAGGLDNITVALVSMNEEDAE"
     gene            complement(4325..5638)
                     /gene="rsmB"
                     /locus_tag="VQ862_000806"
     CDS             complement(4325..5638)
                     /gene="rsmB"
                     /locus_tag="VQ862_000806"
                     /EC_number="2.1.1.176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(967)-C(5))-methyltransferase
                     RsmB"
                     /protein_id="HET3115178.1"
                     /translation="MTKVETARSLALAVLEDVFVNQAYSNIALNKHLKGSQLSAADKG
                     LVTELVYGTVARKLTLEWYLSHFIEDRDQLDSWLYVLLLMSVYQLRYLDKIPDHAVVN
                     EAVELAKLRKKGSEKLVNAVLRRILREGWPDIANIKRKNKRDSIAYSLPVWLVTKLKE
                     EYGEERAKAIFESLLVRNKASIRVTDLSRKEEIQALLEANSSLLATTGLVKEQGHFAG
                     HNLFADGAITIQDESSQLVAPTLDLQGDERVLDACAAPGGKTAHIASYLTTGQVTALD
                     LYDHKLDLIQENAQRLGVEDRVQTQKLDARKVHEFFDQDSFDKILVDAPCSGIGLLRR
                     KPDIKYNKETADFASLQEIQLEILGSVCQILGKGGIITYSTCTIVSEENFQVVKAFLE
                     SHPEFEQVKLEHECKDIMKDGCILITPELYGSDGFFISQFRKISD"
     gene            complement(5631..6566)
                     /locus_tag="VQ862_000807"
     CDS             complement(5631..6566)
                     /locus_tag="VQ862_000807"
                     /EC_number="2.1.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl-tRNA formyltransferase"
                     /protein_id="HET3115179.1"
                     /translation="MTKLIFMGTPDFSATVLKGLLTDDRYEILAVVTQPDRAVGRKKV
                     IQETPVKQAAKEAGLSIYQPEKLSGSPEMEELMKLGADGIVTAAFGQFLPSKLLDSMD
                     FAVNVHASLLPRHRGGAPIHYALIQGDEEAGVTIMEMVKEMDAGDMISRRSIPITDED
                     NVGTLFEKLALVGRDLLLDTLPAYIAGDIKPEPQDTSQVTFSPNIKPEEEKLDWNKTN
                     RQLFNQIRGMNPWPVAHTFLKGDRFKIYEALPVEGQGNPGEILSIGKKELIVATAEGA
                     LSLKQVQPAGKPKMDIASFLNGVGRTLTVGERFGD"
     gene            complement(6579..8975)
                     /locus_tag="VQ862_000808"
     CDS             complement(6579..8975)
                     /locus_tag="VQ862_000808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001162119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein N'"
                     /protein_id="HET3115180.1"
                     /translation="MALAKIIVDVPLMQTDQPYSYRIPEEFEGMLEVGMRVHVPFGKG
                     NRLIQGIVLGLESQSDGEEMEQDLKDIAEVLDFSPVLTPEQLWLAEELRKSVFSYKIS
                     ILKTMLPGFLNSSYDKILYPLEGLSQEERVRLFGSEDSLAFSSLDLAKQAEMMRLTRK
                     GLLGLEYQAVDQKKVKTQSWYEVDHAQLEGVEISTRAKKKLELRDYLLSHPESASLAS
                     LLESYSREQVNFFVDQGAVTIVQKEVQRSAAYFEGIEASRPLELNPEQRQARDAVVSS
                     IGSSQPPFLLQGITGSGKTEVYLQIIQGALDKGKTAILLVPEISLTPQMTERFIARFG
                     DKVAILHSGLSNGEKYDEWRKVERGDAQVVVGARSAIFAPLKNLGVMIIDEEHEAAYK
                     QDSNPRYHAREVAILRAQYNQATLVLGSATPSLESRARAGKGVYQHLRLTQRANPLAT
                     IPEVQVIDFRDYIGQNETSNFTPPLLEAIQDRLVKKEQVVLMLNRRGYSSFVMCRECG
                     TVDTCPNCDISLTLHMDTKTMNCHYCGFSKDIPQVCPNCKSHSIRYYGTGTQKAYDEL
                     AELFPQARIFRMDVDTTRKKGSHQALLDQFGRGEADILLGTQMIAKGLDFPNVTLVGV
                     LNADTALNLPDFRSSERTFQLLTQVAGRAGRAEKAGQVLIQSYNSQHYAIRFAKDQDY
                     EGFYAYEMGIRRQLGYPPYYFTIGITLSHKKEEEVFKRAYEVMNILRSGLSETSPILG
                     PTPKPIARTHNLYHYQILIKYRLEDELGPTLNQVLALTQERENSELRLSIDHEPQQFL
                     "
     gene            complement(9041..9355)
                     /locus_tag="VQ862_000809"
     CDS             complement(9041..9355)
                     /locus_tag="VQ862_000809"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001817694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HET3115181.1"
                     /translation="MMLKPSIDTLLDKVPSKYSLVILEAKRAHELEAGAPATQGFKSE
                     KSTLRALEEIESGNVTIHPDPEGKREAVRRRIEEEKRRKEEEEKKIKEQIAKEKEDGE
                     KI"
     gene            complement(9380..10006)
                     /gene="gmk"
                     /locus_tag="VQ862_000810"
     CDS             complement(9380..10006)
                     /gene="gmk"
                     /locus_tag="VQ862_000810"
                     /EC_number="2.7.4.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000775037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="guanylate kinase"
                     /protein_id="HET3115182.1"
                     /translation="MADRGLLIVFSGPSGVGKGTVRREIFESSENQFQYSVSMTTRAQ
                     RPGEVDGVDYFFRTREEFEELIRQGQMLEYAEYVGNYYGTPLTYVNETLDKGIDVFLE
                     IEVQGALQVKKKVPDAVFIFLTPPDLDELQDRLVGRGTDSAEVIAQRIEKAKEEIALM
                     REYDYAIVNDQVPLAAERVKCVIEAEHFCVDRVIGHYQEMLPKSPTTR"
     gene            complement(10136..11749)
                     /locus_tag="VQ862_000811"
     CDS             complement(10136..11749)
                     /locus_tag="VQ862_000811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Y"
                     /protein_id="HET3115183.1"
                     /translation="MEIMSLAIAVFAVIIGLVIGYVSISAKMKSSQEAAELMLLNAEQ
                     EATNLRGQAEREADLLVNEAKRESKSLKKEALLEAKEEARKYREEVDAEFKSERQELK
                     QIESRLTERATSLDRKDDNLTSKEQTLEQKEQSISDRAKNLDAREEQLEEVERQKEAE
                     LERIGALSQAEARDIILAQTEENLTREIASRIREAEQEVKERSDKMAKDILVQAMQRI
                     AGEYVAESTNSTVHLPDDTMKGRIIGREGRNIRTFESLTGVDVIIDDTPEVVTLSGFD
                     PIRREIARMTMEMLLKDGRIHPARIEELVEKNRQEIDNKIREYGEAAAYEIGAPNLHP
                     DLMKIMGRLQFRTSYGQNVLRHSIEVAKLAGIMASELGENAALARRAGFLHDIGKAID
                     HEVEGSHVEIGMELARKYKEPPVVVNTIASHHGDVEAESVIAVIVAAADALSAARPGA
                     RSESLESYIKRLHDLEEIANGFEGVQTSFALQAGREIRIMVNPGKIKDDKVTILAHKV
                     RKKIENNLDYPGNIKVTVIRELRAVDYAK"
     gene            complement(12092..14839)
                     /locus_tag="VQ862_000812"
     CDS             complement(12092..14839)
                     /locus_tag="VQ862_000812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIR2 family protein"
                     /protein_id="HET3115184.1"
                     /translation="MEENYNLSITQIKNSIKENSLVLFVGAGISANSNLPTWGELIQS
                     LKKELNIPEERTDSPLRIAQYYYDTFGKNQYTKKIEEIFFKKGLSKPNELHKLIEKIA
                     PKHIITTNYDSLLESQFESGLLKYNVVAEDKDIPYTSSERYLIKMHGDFSKKNIVLKE
                     DDYLDYHLNFPMISTLIQSLIMNHTLLFVGYSLSDSTFNSIFRMIQNTFKLDAKNAYF
                     YTPEEPSMIIREYYKKQGIFIISNEENLGQETSEKQNKLYCRTKDFLEVLSENRSQDV
                     NNADDLWNQLAFLDRLSFIDAKDFSRYSDLKKRALNWDDEYCWFGNDQLRFEIDGHEE
                     LRIMVSKKSLLNRFLDMEIGEPRDLKGNRFLSKAFKLYEEKQYSLAKAKFRELANIAF
                     RQKDYFNFLVCEFNFQQIQIIDRYEKTPSYAEPLYDGELSELTEQILNSVTGDEKKII
                     EFFRDSILNFNFLYRKLETINELFDEIREEHESYRRGGWSANNHLFNAEFTVKNLYNF
                     LKLNCLCVEHYKIYKSIINRYLEILLLSYDNSYVNPDSSIFDRTSSWLKNLDLDDVKL
                     ILPNIDFKVVNLYFRNYSFGKIKVTEEAKDYLLNRITYLQERLEITEDENLRELKNML
                     IFLPLVDDIDIEKVIEILNNQTLYYNWSEEFRRIIKIVLDNMDVIDKDSLKSKIIGIV
                     NKHLNEILEKNFSLYNSVYPLYSQLLEYCSTDQETAIIVLEKFNTDILRIKYKNDDIK
                     NIIEYSDLICHLFKYFEKDIKDDILDTLKVYEESENIIYHKVIDLMSYNVYDFPQIQN
                     KIYHYLIKRINDKRVEGVKTFPDPREKSVSDLYNLSRKGYFSDFEILKDIEEDIRGLY
                     PEVDWTWFHDRSDDVIHRLLEHRTPNNIKTYFSKNEEDNKLINEYILKAFDEDKLILK
                     K"
     gene            complement(15186..16283)
                     /locus_tag="VQ862_000813"
     CDS             complement(15186..16283)
                     /locus_tag="VQ862_000813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000156376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase"
                     /protein_id="HET3115185.1"
                     /translation="MTITGIIAEFNPFHNGHKYLLDQAEGLKIVAMSGNFMQRGEPAI
                     VDKWTRAQMALENGADLVVELPFLVSVQAADFFGQGAVDILDRLGIDSLVFGTEEVLD
                     YQKIADLYTEKGAEMEKFVKNLPDSLSYPQKTQAMWKEFAGLDFSGNTPNHVLALAYA
                     KAVAGRNIKLHPIQRQGAGYHSVNKDVDFASATALRQHQKDQDFLERFMPSVALFEQA
                     SKVIWEDYFPLLRYQILSNPDLTTIYQVNQEMAVRIKEAIKTAQSVEELVELVTTKRY
                     TKARVRRLLTYILVQARENVLPEAIHVLGFTEKGRQHLKSLKGQVNLVSRIGKEPWDA
                     MTQKVDQIYQLGKPSIAEQNFGRVPIRIETN"
     gene            complement(16293..17039)
                     /locus_tag="VQ862_000814"
     CDS             complement(16293..17039)
                     /locus_tag="VQ862_000814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000605145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HET3115186.1"
                     /translation="MIMATYETFAAVYDAVMDDSLYDKWTNFSLRHLPKTKERKKLLE
                     LACGTGIQSVRFSQAGFDVTGLDLSADMLKIAEKRATSAKQKIAFIEGNMLNLSKAGK
                     YDFVTCYSDSICYMQDEVEVGDVFKDVYNALNEEGVFIFDVHSTYQTDEVFPGYSYHE
                     NAEDFAMLWDTYEDEVPHSIVHELTFFIKEADGSFSRHDEVHEERTYEILTYEILLEQ
                     AGFKSFKLYADFEDKEPTETSTRWFFVAQK"
     gene            complement(17142..17495)
                     /gene="rsfS"
                     /locus_tag="VQ862_000815"
     CDS             complement(17142..17495)
                     /gene="rsfS"
                     /locus_tag="VQ862_000815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001003018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome silencing factor"
                     /protein_id="HET3115187.1"
                     /translation="MNEKELLELVVKAADEKRAEDILALDVQDLTSVTDYFVITSSMN
                     SRQLDAIAANIREKVAQAGFKGSHIEGDAAGGWVLLDLGAVVVHIFSEEMRAHYNLEK
                     LWHEANSVDISEALA"
     gene            complement(17508..18008)
                     /locus_tag="VQ862_000816"
     CDS             complement(17508..18008)
                     /locus_tag="VQ862_000816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000844697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HET3115188.1"
                     /translation="MKTAFIIIDVQNVLVETGFQTKSLLEKISYLQNQARSKNIEIIY
                     VQHIENSEAQTSEDWQLSALLNRKPAEKVFQKKYNSIFKETGLKEYLDKQGIEKLVLC
                     GMQTEYCVDTSVKVAFEYGYQLIVPEGAVTTFDGDDIPAETINEFYEDIWEECFADVL
                     DYKHIF"
     gene            complement(18009..18602)
                     /gene="yqeK"
                     /locus_tag="VQ862_000817"
     CDS             complement(18009..18602)
                     /gene="yqeK"
                     /locus_tag="VQ862_000817"
                     /EC_number="3.6.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bis(5'-nucleosyl)-tetraphosphatase (symmetrical)
                     YqeK"
                     /protein_id="HET3115189.1"
                     /translation="MSYQDYINCSREALLEKMAELLPEKRLTHCLGVERAAMELAQRF
                     GVDVEKASLAGLLHDYAKKLSDQEFLDLIDRYQLDFDLKNWGNNVWHGMVGIYKIQED
                     LDLHDSEILRAIEVHTVGAGQMTDLDKVIYVADYIEHNRAFPGVDVAREIASLSLNKA
                     VAYETARTVEYLAHQGFPIYPQTLETYNAFVHYLKED"
     gene            complement(18602..19231)
                     /locus_tag="VQ862_000818"
     CDS             complement(18602..19231)
                     /locus_tag="VQ862_000818"
                     /EC_number="2.7.7.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide adenylyltransferase"
                     /protein_id="HET3115190.1"
                     /translation="MTIELLTPFTKVELEPEIKEKKRKQVGILGGNFNPVHNAHLIVA
                     DQVRQQLGLDQVLLMPEYQPPHVDKKETIPEHHRLKMLELAIEGIDGLVIETIELERK
                     GISYTYDTMKILTEQHPDTDYYFIIGADMVDYLPKWYRIDELVDMVQFVGVQRPRYKA
                     GTSYPVIWVDVPLMDISSSMVRDFIAQGRKPNFLLPQPVLDYIEKEGLY"
     gene            complement(19283..19594)
                     /gene="yhbY"
                     /locus_tag="VQ862_000819"
     CDS             complement(19283..19594)
                     /gene="yhbY"
                     /locus_tag="VQ862_000819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000060164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome assembly RNA-binding protein YhbY"
                     /protein_id="HET3115191.1"
                     /translation="MSLTSKQRAFLNSQAHTLKPIIQIGKNGLNDQIKTSVRQALDAR
                     ELIKVTLLQNTDENIHEVAEILEEEIGVDTVQKIGRILILFKQSSKKENRKISKKVKE
                     I"
     gene            complement(19808..20914)
                     /gene="yqeH"
                     /locus_tag="VQ862_000820"
     CDS             complement(19808..20914)
                     /gene="yqeH"
                     /locus_tag="VQ862_000820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000391231.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YqeH"
                     /protein_id="HET3115192.1"
                     /translation="MEEILCIGCGATIQTTDKAGLGFTPQSALEKGLETGEVYCQRCF
                     RLRHYNEITDVQLTNDDFLKLLHEVGDSDALVVNVIDIFDFNGSVIPGLPRFVSGNDV
                     LLVGNKKDILPKSVKSGKISQWLMKRAHEEGLRPVDVVLTSAQNKHAIKEVIDKIEHY
                     RKGRDVYVVGVTNVGKSTLINAIIQEITGDQNVITTSRFPGTTLDKIEIPLDDGSYIY
                     DTPGIIHRHQMAHYLTAKNLKYVSPKKEIKPKTYQLNPEQTLFLGGLGRFDFIAGEKQ
                     GFTAFFDNELKLHRSKFEGASAFYDKHLGTLLTPPNSKEKEDFPRLVQHVFTIKDKTD
                     LVISGLGWIRVTGIAKVAVWAPEGVAVVTRKAII"
     gene            complement(20917..21507)
                     /locus_tag="VQ862_000821"
     CDS             complement(20917..21507)
                     /locus_tag="VQ862_000821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqeG family HAD IIIA-type phosphatase"
                     /protein_id="HET3115193.1"
                     /translation="MDCFILVTKENCEKKLRKGARMAIENYIPDFAVEAVYDLTVPSL
                     QAQGIKAVLVDLDNTLIAWNNPDGTPEMKQWLHDLRDAGIGIIVVSNNTKKRVQRAVE
                     KFGIDYVYWALKPFTFGIDRAMKEFHYDKKEVVMVGDQLMTDIRAAHRAGIRSILVKP
                     LVQHDSIKTQINRTRERRVMRKITEKYGPITYKKGI"
     gene            complement(21459..22367)
                     /locus_tag="VQ862_000822"
     CDS             complement(21459..22367)
                     /locus_tag="VQ862_000822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HET3115194.1"
                     /translation="MVLEKQLGNGCTWIDLDLGKLNKLEDLSEIYGLDKETIEYALDR
                     NERAHMDYHRESGTVTFIYNVLDVKKDKAYYETFPMTFIVEHRRLITISNTKNAYVIE
                     QMTRYLESHDTLSIYKFLFASLEIISNAYYPVIEQMDKSRDEVNDLLRQRTTKKNLFA
                     LSDLETGMVYLTAAAKQNRILLEHIQGHALYRSFDEIEREQFDDAMIEAHQLVSMTDL
                     ISQILQQLSASYNNILNNNLNDNLTTLTIISVLLAVLAVVTGFFGMNVPLPLTDEPHA
                     WLYISLASAGLWIVLSLLLRKIAKKS"
     gene            complement(22424..22984)
                     /locus_tag="VQ862_000823"
     CDS             complement(22424..22984)
                     /locus_tag="VQ862_000823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel"
                     /protein_id="HET3115195.1"
                     /translation="MQKFIQAYIEKLDVTTIIENILTKVISLLLLLIVFYIAKKMLHT
                     MVQRIVKPSLKMSRHDVGRQKTISRLLENVFNYTLYFFLLYCILSILGLPVSSLLAGA
                     GIAGVAIGMGAQGFLSDVINGFFILFERQLDVGDEVVLTNGPITVSGKVVSVGIRTTQ
                     LRSEEQALHFVPNRNITVVSNFSRTD"
     gene            23123..24331
                     /gene="sstT"
                     /locus_tag="VQ862_000824"
                     /pseudo
     CDS             23123..24331
                     /gene="sstT"
                     /locus_tag="VQ862_000824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000713440.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine transporter SstT"
     gene            24399..25352
                     /locus_tag="VQ862_000825"
     CDS             24399..25352
                     /locus_tag="VQ862_000825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000028179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HET3115196.1"
                     /translation="MSISQRTTKLILATCLACLLAYFLNLSSAVSAGIIALLSLSDTR
                     RSTLKLARNRLFSMLLALAIGVLAFHLSGFHIWSLGLYLAFYVPLAYKMGWEIGITPS
                     TVLVSHLLVQESTSPDLLVNEFLLFAIGTGFALLVNLYMPSREEEIQHYHTLVEEKLK
                     DILQRFKYYLSRGDGRNRAQLVAELDTLLKEALRLVYLDHSDHLFHQTDYHIHYFEMR
                     QRQSRILRNMAQQINTCHLAASESLILAQLFSKIAGQLSQTNPASDLLDEIERYLEVF
                     RNRSLPKTREEFETRATLLQLLREAKTFIQVKVDFYQKYRQ"
     gene            25495..25875
                     /locus_tag="VQ862_000826"
     CDS             25495..25875
                     /locus_tag="VQ862_000826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HET3115197.1"
                     /translation="MTYLEKWFDFNRRQKEIESLLEETIAQQSEQSLTLKEFYLLYYL
                     DLAEEKSLRQIDLPDKLHLSPSAVSRMVARLEAKNCGLLSRMCCHQDRRSSFICLTND
                     GQKTLASLQKTVEESLEAGLDFLI"
     gene            25974..26195
                     /locus_tag="VQ862_000827"
     CDS             25974..26195
                     /locus_tag="VQ862_000827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4649 family protein"
                     /protein_id="HET3115198.1"
                     /translation="MIEITYIDASKNERTVTFESYEDFERSQQACLIGVADYYPVQKL
                     TYKGHNLDYHGTYGDIFFYLMKQDLSQYN"
     gene            26212..26526
                     /gene="trxA"
                     /locus_tag="VQ862_000828"
     CDS             26212..26526
                     /gene="trxA"
                     /locus_tag="VQ862_000828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003004519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HET3115199.1"
                     /translation="MAKAITDATFEQETKDGLVLVDFWATWCGPCRMQGPILDKLSEE
                     LSEDVLKIVKMDVDENPNTARAFGIMSIPTLLFKKDGQVVKQVAGVHTAEQIKAIIAE
                     LS"
     gene            26831..27364
                     /gene="queF"
                     /locus_tag="VQ862_000829"
     CDS             26831..27364
                     /gene="queF"
                     /locus_tag="VQ862_000829"
                     /EC_number="1.7.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000828792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent 7-cyano-7-deazaguanine reductase
                     QueF"
                     /protein_id="HET3115200.1"
                     /translation="MKRQSALVVFSGGQDSTTCLFWAMQHYETVEAVTFAYGQRHHLE
                     IQITREIAKEQGIRHHILDMSLLGQITAQPDFATIHISYIPDKLCVESKSLKLYLFSY
                     RNHGDFHENCINTIGKDLVNLLDPRYLEVWGKFTPRGGISIDPYYNYGKQGTKYEGLA
                     EQRLFQHDLYPEKIDNR"
     gene            complement(27618..28286)
                     /locus_tag="VQ862_000830"
     CDS             complement(27618..28286)
                     /locus_tag="VQ862_000830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000714831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin"
                     /protein_id="HET3115201.1"
                     /translation="MKKFVAELIGTFMLVFVGTGAVVFGNGLDGLGHLGIAFAFGLAI
                     VVAAYSIGTVSGAHLNPAVSIAMFVNKRLSSSELVNYILGQVVGAFIASGAVFFLLGN
                     SGMSTASLGENALANGVTVFGGFLFEVIATFLFVLVIMTVTSESKGNGAIAGLVIGLS
                     LMAMILVGLKITGLSVNPARSLAPAVLVGGAALQQVWIFILAPIAGGVLAALVAKNFL
                     GTEE"
     gene            complement(28397..29188)
                     /locus_tag="VQ862_000831"
     CDS             complement(28397..29188)
                     /locus_tag="VQ862_000831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2785 domain-containing protein"
                     /protein_id="HET3115202.1"
                     /translation="MYQDLLRKIAEEKPNYNQEEIQWLLDHLGDPSPEIRDDLVFTSF
                     ARGIQEELFTQEQFHFIAEVVLADGGLDKEIDKVGLSTLERSFRALVYANLLSVDANQ
                     QSVFYQGLQSEIRNVLLNQGLHYLSKEKDTTGFSSQYGWVHAFAHGADLLKEVVCHPD
                     FPKNRVHEVFDILGQLFKRMSIRFTDDEDWRLARVIYEPILQGKLAQEQVASWIKTVD
                     FPIEEREDFYKFSNFRTCLLEVYVQLDQRNSLQDELKEAIQSFQY"
     gene            complement(29612..30376)
                     /locus_tag="VQ862_000832"
     CDS             complement(29612..30376)
                     /locus_tag="VQ862_000832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET3115203.1"
                     /translation="MFKLSFHSIGHVVVRNYMSFRNLFKISIVPNLIDPLFYLLAMGF
                     GVGAYLTHVNGMLYRDFVITGLIAATAMSAATAETTVNAFIQYKIEKTYDAMLMTPIN
                     TNDIVVGQAIWAGIRAVIFGGIFWLISMLITAHFHVLMLLIPLILFIVGYLFGVLGLI
                     FTYLAPSREFLNYYNVLVIRPLYMFSDTFFPITSLPPILGDLTWFSPLYHATRMIRII
                     WGGEVTGLYLHLIWLIALALLITVLPMYMLHRRYYR"
     gene            complement(30369..31139)
                     /locus_tag="VQ862_000833"
     CDS             complement(30369..31139)
                     /locus_tag="VQ862_000833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000966490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3115204.1"
                     /translation="MLYLWGKERVKKLSVKNLKKQYGSYEAVKGISFELGDGECLGIL
                     GINGAGKTSTLKMIYSLTSISSGEIDILGQNIETNRRKSKSCLGIVGQEDMLDMTLNV
                     YDNLFAHGLCYGISSVELRKRIDSLLDFVQLSKHAQKMVNQLSGGMRRRLVLARALIN
                     RPDIIILDEPTVGLDIQSRNIIWDKLLELKELGVSIIITSHYMNEIEYLTDRVLMLHQ
                     GTIKEEGTVEDLLIKYDADNLETLFWGLTGTEKEDLHV"
     gene            31386..32063
                     /locus_tag="VQ862_000834"
     CDS             31386..32063
                     /locus_tag="VQ862_000834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000433071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HET3115205.1"
                     /translation="MKPDIFIITKLLSDPSRMHILDILMDGKAHTVNEIASFTKIKQH
                     TVSYHLKLLTEAQVTTLQTYGRFHYYSLKSAAIAEMLEFLSFYSPQRDVKSYKQHIHK
                     KELKVARTCYDHIAGELGISITNYLLQENLLSESEKDFQLTEAGKSYFQRKLHIDTDE
                     LKKKKRKFCPKCLDWSERKNHVGGALGNALLEFFSEKQLVIPAQTPRSLTITEKGKEF
                     LEKEWGI"
     gene            complement(32123..33919)
                     /gene="pepF"
                     /locus_tag="VQ862_000835"
     CDS             complement(32123..33919)
                     /gene="pepF"
                     /locus_tag="VQ862_000835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000435555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HET3115206.1"
                     /translation="MEQKHRSEFPEKELWDLTALYQDREDFLRAIEKAREDINQFSRD
                     YKGNLHTFEDFEKAFAELEQIYIQMSHIGNYAFMPQTTDYSNDEFANIAQAGMEFETA
                     ASVALTFFDDALVAADEEVLDRLGKLPHLTAAIRQAKIKKAHYLGADVEKALTNLGEV
                     FYSPQDIYTKMRAGDFEMADFEAHGKTYKNSFVTYENFYQNHEDAEVREKSFRSFSEG
                     LRKHQNTAAAAYLAQVKSEKLLADMKGYDSVFDYLLAEQEVDRVMFDRQIDLIMKDFA
                     PVAQRYLKHVAKVNGLEKMTFADWKLDLDSALNPEVTIDDAYDLVMKSVEPLGQEYCQ
                     EVARYQEERWVDFAANSGKDSGGYAADPYRVHPYVLMSWTGRLSDVYTLIHEIGHSGQ
                     FIFSDNHQSYFNAHMSTYYVEAPSTFNELLLSDYLENQSNDPRQKRFALAHRLTDTYF
                     HNFITHLLEAAFQRKVYTLIEEGETFGASKLNSIMKEVLTDFWGDAIEIDDDAALTWM
                     RQAHYYMGLYSYTYSAGLVISTAGYLHLKNSETGAEDWLNLLKSGGSKTPLESAMIIG
                     ADISTDKPLRDTIQFLSDTVDQIIAYSAELGE"
     gene            complement(33930..34673)
                     /locus_tag="VQ862_000836"
     CDS             complement(33930..34673)
                     /locus_tag="VQ862_000836"
                     /EC_number="2.1.1.193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001188214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (uracil(1498)-N(3))-methyltransferase"
                     /protein_id="HET3115207.1"
                     /translation="MQQYFVKGSAISPVTIENKETSKHMFQVMRLKEEDEVTLVFDDG
                     IKRLARVLDMENRQFELVQELNDNVELPVQVTIASGFPKGDKLEFIAQKVTELGASQI
                     WAFPADWSVAKWDGKKLGKKVEKLEKIALGAAEQSKRNIVPSIKLFEKKADFLTQLDQ
                     FDSIIVAYEESGKEGEAAALLQAVTGLETGAKLLFIFGPEGGLSPAEIESFEAKGAVL
                     VGLGPRILRAETAPLYALSALSVLVELEK"
     gene            complement(34675..35628)
                     /locus_tag="VQ862_000837"
     CDS             complement(34675..35628)
                     /locus_tag="VQ862_000837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000970787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11 methyltransferase"
                     /protein_id="HET3115208.1"
                     /translation="MMETWQELKVTVKREGEELVSNLLIELGAQGVAIEDSMDYVGNV
                     DRFGEIFPEVEQQEEIVVTAYYPDTVDVTVVEADLQARISELTDFMDLGELKIGTTAL
                     AEEDWADNWKKYYEPARITHDLTIVPSWTDYEATAGEKIIKLDPGMAFGTGTHPTTKM
                     SIFALEQVLRGGETVLDVGTGSGVLSIASSLLGAKEIFAYDLDDVAVRVAQENIELNP
                     GMENIHVAAGDLLKGVEIEADVIVANILADILIHLTEDAYRLVKDEGYLIMSGIIKDK
                     WDMVRELAESAGFFLETHMVQGEWNACVFKKTKDISGVIGG"
     gene            complement(35763..36191)
                     /locus_tag="VQ862_000838"
     CDS             complement(35763..36191)
                     /locus_tag="VQ862_000838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HET3115209.1"
                     /translation="MELEISDFQGCKIALFCGDKLLTILRDDKDDIPCPNMWELPGGG
                     REGDESPFECARREVYEELGIHLDEDCLLWSKIYPSVIFKGKKSVFMVGQLRQEQFDN
                     IIFGDEGQGYQLMNVEEFLSSSQVVPQLQERLKDYLKVSD"
     gene            complement(36172..37260)
                     /locus_tag="VQ862_000839"
     CDS             complement(36172..37260)
                     /locus_tag="VQ862_000839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000719715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-2 protease family protein"
                     /protein_id="HET3115210.1"
                     /translation="MKKIGTYLVYVLAVVFIMLAFACGTIAFAELGYSAVLAFTFGYA
                     FALLSMYLIFILHELGHAFCGYLTGYRLVAFGLGHFILTKKSGRFHLSRTAILKNVGA
                     QYIGLKEDESDQRIILMLSGGLMVHLGLILLAIVFGFLTRSWYFAGTWIFLNLSFFLN
                     NILPVDITDGAKIWELLQHPENTKYAYLVLRHSAQTLLAPQEYDLKDFVQAVPEDARG
                     SFADGVLGMQGEVSILEGKEEVAKQQFQALLERTTTPMMQTVAQLSLLHIALLEGDFE
                     QAEQYASIRQVKSFLSLKLSNLQVIQAWYQLKVKKDVDRTRKALKIARQKMDSSRMLR
                     DEKRYYENLLAELEKEMLEGTEDGTRNF"
     gene            complement(37279..37749)
                     /locus_tag="VQ862_000840"
     CDS             complement(37279..37749)
                     /locus_tag="VQ862_000840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000257105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3013 family protein"
                     /protein_id="HET3115211.1"
                     /translation="MATYGFLDVLEEELDKNFPFDFEISWDKRNHAVEVSFLLEAQNA
                     AGVEMVDEDGEVSSDDILFEEAVLFYNPAKSTVNAEDYLTVIPYLPKKGFSREFLAYF
                     ALFLKDTAEVGLDTLMDFLEDPEAEEFVMEWNQEVFEEGKVGLEEGGFYPYPRY"
     gene            complement(38040..38492)
                     /locus_tag="VQ862_000841"
     CDS             complement(38040..38492)
                     /locus_tag="VQ862_000841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000961815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicB family
                     antitoxin"
                     /protein_id="HET3115212.1"
                     /translation="MLVTYPALFYYDDTDGTEATYFVHFPDFEYSATQGEGISEALAM
                     GSEWLGITVADLIESDGELPQPSDINSLSLIDNDPFKDDEDFVSTYDLDKSFISMVSV
                     DVSEYLGSQEPIKKTLTIPKWADKLGREMGLNFSQTLTDAIADKKVQA"
     gene            complement(38529..38707)
                     /locus_tag="VQ862_000842"
                     /pseudo
     CDS             complement(38529..38707)
                     /locus_tag="VQ862_000842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397531.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicA family
                     toxin"
     gene            complement(38844..39023)
                     /locus_tag="VQ862_000843"
     CDS             complement(38844..39023)
                     /locus_tag="VQ862_000843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3115213.1"
                     /translation="MNLIFEEYQFVKIGDKKYRVRSVPMIHSTPPQSVLDRDTFTIDY
                     TDDELLDKEAVFTTH"
BASE COUNT        11250 a         8872 c         7179 g        11741 t
ORIGIN      
        1 attcgctaat tgttttttta gggcgattga tttttacttc cgtcgcatca atcattaccg
       61 tgtcctcaga actgagagga gttcttgaaa tcgtaacacc actttgaaca agagttactt
      121 caacccattg gctccgacgg attaagttgc tttcgtgaat accaaaatca gccgcaattt
      181 gttcataagt tcgatattct cgcacatata gaaagcgttg ttaatttatt tatctcattt
      241 ttcagaaaat tcttttattt ctgtaaaatc tacgatactc gatgtgtttt tatataatga
      301 tacagtctga gaatcactgt tccgctagcc attccaatag agattaccaa agccaacatg
      361 acaaccaagg tcgcacttgc cagtgcttta ttatagtccc ctgtcacaaa aaaggcagtt
      421 gttcggtagg agagataacc tggaaccagc ggtgccaaaa tggccaagat aaagaccaca
      481 gcaggtgtct tataaagaat acttaaaatc tggctgacac aagaaccaat aatggctgca
      541 atgaaggtag ctacaatgac attggtcggt tccttgagca agagatagat tagccagaca
      601 gtcatgccca aaatccctcc aggtaagagc atagaccgtt gcacattgag tacgattaaa
      661 aaagtgataa tggcaagaaa acttgctact gcttgtaata aaaaggttgt tagtgtcata
      721 ttagttcacc aataccaagg cgacagaagt tcctgcccct aaagcgaggg taatgagcag
      781 ggattcaaac atcttactca taccagagtt tatgtggttg gtcataatat cacggaccgc
      841 attggtcaag gcaatacctg gtacaaacgg catgaccgca ccagctataa tcaaatctgc
      901 cgttgaagga aaacctgtgt agcgagccca aaactgggca attatcccaa agacaaaggc
      961 tccagcaaag gctgtcacaa agggaattcg gataaatttt tccacataga gggaaaaggc
     1021 aaaaccaaat aaggtcgcca ctcctgcccc aagtgcgtcg tagatatttc cgctaaacat
     1081 aactgaaaag aaaggagcac taaaggtcgc agccagagtt acctgcaact tagtataggg
     1141 aaggggttga gcttgcaagg ccgtcaattg cttaaaggct gtttctaaat caatctgccc
     1201 cccaaccagc tgacgagaaa tctggttcac atcgcagact ttttcgatgt tataagaaga
     1261 ggaggtcacg cgcttcatgc gcgaaatatt ggtattttca atagagaaaa agatagcggc
     1321 aggcatggca aggacattgc aatccacaat cccctgcgaa tgcgcgattc gaatcatggt
     1381 atcttctaca cgatggattt ctgagccact tttaaggaga atagtccccg ctagcataat
     1441 cacatcaatg acggcattta attcttttga ttcttccatg ctttcctcct tttatcaact
     1501 ccctctattc tatcacaaat ctggactcaa aaaaaatctt tgccatgaaa tcatgacaaa
     1561 gattgattac tcattttgat tatccatcta cttttaagga gtagctgaag ttgttttagg
     1621 tttgtagatt gaaatcttga ctctagtctt attgaggtct accttttcac ctgctctagg
     1681 actttgttca acaaccatgc cttctgcact acctgcaggc gctgtcgtca cttctacaac
     1741 ttctatatta gcttccttaa tcccaacaat ttgaatcaaa ttgttcttag taaactccaa
     1801 gctggaacca atgtaactcg gcatggcaac acttgtaact tttttagcta ctgtcaagac
     1861 aatttgagta ggtttactca catcataagt cgttccggca cctggacttt gtttcataat
     1921 cgttcctggt tcgctttcgc tggactcttc ttcctctatc ttaatcaaat tctcaggaac
     1981 cttcttctgc ttgagttctg agattacttc tgtagagttc cgtccaatat agttccctaa
     2041 ttgaatcgtc gtagcttttt tagctactgt caaaacaatt tgagttgcct tgctcaagtc
     2101 ataggtcgta ccttctggta gactttgctt caggaccgtt ccagcctcac tctcattcga
     2161 ctcttcttcc tcaattttaa tcaaattatc tggaactttt ttctctttta attccgcgat
     2221 aacatcagaa gatttccggc cgacataatt actaatttgg aaggattgtt tgcctgatga
     2281 gacaaccaga ttgattttcg ttccttcttt tcgaccagtt ccagcgccag gatctgtacg
     2341 gataatccgc ccttcttcca ccttttcact agcctctgtc ttctcctcac caatctcaaa
     2401 attggctttt ttgagcgttg ccttggcctc tgcaactgtc tgacctgcca catctggaat
     2461 ggcaatggtt gcaggagttc tggatagtat ccaaataaga gaagctgcca ccaatacaag
     2521 gctggccaac aaaatcaggt aacgcatctt aaatctatgt tttttcggtg cttgtggttg
     2581 gtaagtttcc tctgtcacag cctggcttgg gtttttgatt gatttgtgtt ctgtctgcgc
     2641 ttgaacctta ggaatagatg tcaaggtact ctgagaaacc ttcggcaagg tcttggtatc
     2701 tgccttgctc gtttcatcaa agattaactt actttcattt ctacgattgt aggacaagct
     2761 actagacaag tccacataca tctctgaaac cgagcggtag cgattggtca actttttagc
     2821 agttgccttg ataataacat tttctaaagc ctgaggtaca gatggatttt ctgcaataac
     2881 ggacggcagg ggtttctgga aatgctggag ggcaatggtc accgcgctat ccccgtcata
     2941 agggatatgg cctgtcaaca tctcatagaa aataatcccc atggcataga tatcactctg
     3001 cacagtcgcc ttcgaaccac gcgcctgctc tggtgacaag taatgaactg agcccaacat
     3061 cgagttagtc tgggtcagac ttgtctctgc aaaggctaca gcaatcccaa agtctgtgac
     3121 cttggccgtc ccatctggtg tcaaaaggat attttgaggt ttcaagtccc tgtgaacaat
     3181 tcctcgagta tgggccaagc gcatagccaa gagaatttgt cccatgatac ggactgcttc
     3241 ttcattagaa agaggataat gttccttgat atagcgtttg aggtctagtc cagcaacata
     3301 ctccattgca agatactgtt gaccgtcttc ctcaccaata tctgttatcc gaacgatatg
     3361 aggatggtct agatctgcca tagctctcgc ttcacgctga aaacgagcta cagctatcgg
     3421 gtccgtctgg tagttggtcc tcagaacctt cactgccact tcttccccat ctaagattaa
     3481 gtctttggct aggtagacat ccgccatacc tcctcgacca atctgtttga caatccgata
     3541 gcgtccggca aaaatcttgc cgatttggat cattctgcat cctcctcgtt catagaaaca
     3601 agggcaaccg taatgttgtc taaacctcct gcattgttag caaaacgaac aagtgtctcc
     3661 gttttatctg ctaaaggaat atcactggtt acaatatcac gaatctcact gcctgaaatc
     3721 atgttggtca agccgtcact attgagcaag agatagtcac ctgactcaag gataactgtc
     3781 ccaaaatcag gctgaatttc atctttttgc ccaatagact gggtgataat atttttttgc
     3841 ggatgagctt ctgcctcttc tggtgtcaat tgaccagcct tgagcaattc attaaccaag
     3901 gaatgatcgc tcgtcaactg atggtattct tctccacgaa tcaagccgat acgcgaatca
     3961 ccaatatgag catagatagc ctgattatca ataatagcaa ggacttccaa agtagttccc
     4021 atgcctctgt aagcttcatc ctgaccaagc tggtgaatct tttgattttc aatttctagg
     4081 taatgggcga accattcacg cacttcattg actgtatcga tctgggtatc aacccaagct
     4141 acacccaggt ctgtgaccgc catttcacta gcgatattcc ctgcacgatg acctcccatc
     4201 ccatcagcta aaataatcat ggtacgtcca gctctattga catagtggtt gacatagtct
     4261 tggttatttg ttcgtttctg accaacatct gttaataatg aaatttccat gtgtcagttc
     4321 cttcctaatc cgatatcttg cgaaattgac tgatgaagaa tccatcactt ccatacaatt
     4381 caggtgtaat gaggatacag ccgtctttca tgatatcctt acattcatgt tctagtttta
     4441 cctgctcgaa ctcgggatga ctctctaaaa aggccttaac gacttgaaaa ttctcctctg
     4501 agacgatagt gcaggtgcta taagttatta taccaccttt gcctagtatt tgacaaacac
     4561 tacctaatat ttctaactga atttcctgca aggacgcgaa atctgccgtt tctttattgt
     4621 atttgatatc tggttttcgg cgcaaaagac cgattcctga acaaggagca tccaccaaaa
     4681 tcttatcaaa ggaatcctgg tcaaaaaact catgcacctt tctggcatcc aatttttgag
     4741 tttgaacccg atcttcaact cccagacgtt gggcattttc ttgaattaaa tccaacttgt
     4801 ggtcgtacaa gtccagagca gtaacctgac ctgtcgtaag ataagaggct atatgggctg
     4861 ttttcccacc tggagccgca caggcatcaa gcactcgctc atcaccttgt aaatcaagcg
     4921 tcggagcaac cagctgactg gactcatctt ggatggtaat ggctccatcc gcaaacaaat
     4981 tatgccctgc aaaatgccct tgctccttaa ccagaccagt ggttgctaaa agggaactat
     5041 tcgcctccaa caaggcttgg atttcctctt ttcgacttag gtctgttaca cgaatactag
     5101 ctttgtttcg cactaacaag ctttcaaaga tggcttttgc tctctcctct ccgtattctt
     5161 ccttgagttt ggtaactagc caaactggga gagaataggc aatggagtca cgcttgtttt
     5221 ttcgcttgat gttagcaata tctggccagc cttcacgcaa gatacggcga aggacagcgt
     5281 tgaccaattt ttcactgcct tttttacgga gtttggccaa ttccactgct tcattgacca
     5341 cagcatgatc tggaatcttg tccaaatagc ggagttggta gacactcatg agaagaagga
     5401 catagagcca gctgtctaac tggtctctgt cttcgataaa gtgggatagg taccattcca
     5461 gagtcagttt acgggctacc gttccataga ctagctcggt cactaagccc ttgtctgctg
     5521 cagagagctg actccccttg aggtgtttat ttaaggcgat atttgaatat gcttggttca
     5581 caaaaacatc ctctagcact gctagagcta aacttctagc cgtttctact ttagtcacca
     5641 aatcgttctc ctacagtcaa tgtacgtcca actccgttga ggaaggaagc aatgtccatc
     5701 ttaggcttac cagctggctg cacttgtttg agggatagag ccccttcagc cgttgcgaca
     5761 atcaattctt tcttgccgat agagagaatc tcacctggat ttccctgacc ttctactggt
     5821 agggcttcat aaatcttaaa gcggtcgccc ttaaggaaag tatgggcaac aggccagggg
     5881 ttcattccac gaatttggtt aaagagttga cgattggttt tgttccagtc cagtttttct
     5941 tcctctggct ttatatttgg agagaaggta acctgactcg tatcctgcgg ttcaggtttg
     6001 atatcaccag caatataggc aggcagagtg tccaaaagca aatcacgacc aactagcgcc
     6061 aatttttcaa acaaggtgcc aacattgtcc tcatctgtga tcggaatgct gcgacgagaa
     6121 atcatatctc ctgcatccat ttccttaacc atttccatga tggtcacacc agcttcctca
     6181 tccccttgaa tcaaggcata atggataggc gcaccaccac ggtgtctagg aaggagggag
     6241 gcatgaacgt tgacagcaaa gtccatgcta tcaaggagtt tgcttgggag aaactgccca
     6301 aaagcagcag tcacaattcc atctgctcct agcttcataa gttcttccat ctctggactt
     6361 ccagataatt tttcaggttg gtagatagat agtcctgctt ccttggcagc ctgcttgact
     6421 ggggtttctt ggataacttt tttacgacca acagcacggt ctggctgggt cacaacggct
     6481 agaatttcgt aacggtcatc tgtcaaaagt ccttttaaga ctgttgctga aaagtcgggg
     6541 gtccccataa agattagttt tgtcatatct tctccttctt ataaaaattg ctgcggctca
     6601 tggtcaatgc tgagacggag ctcactattt tcccgttctt gagtcaaggc caagacctgg
     6661 ttgagggtcg gccccagctc atcttctaaa cggtatttaa ttaaaatctg gtaatgatag
     6721 aggttgtggg tacgggcaat cggttttggc gttggcccca gaatgggact ggtctctgac
     6781 aagcctgacc gcaaaatgtt catgacttca taggcacgtt tgaaaacctc ttcttctttc
     6841 ttgtgagaaa gggtaatacc aatcgtgaaa tagtaaggtg gatagccgag ttgtcgtctg
     6901 attcccattt cataggcata aaagccttcg taatcttgat ccttggcaaa tcgaatagca
     6961 tagtgctgcg aattgtagga ctgtatcaag acttgacctg ctttttcagc ccgacctgct
     7021 cgacctgcta cctgagtcaa gagctggaag gttctctcag aagaacggaa atcaggcaga
     7081 ttcaaggccg tatccgcatt tagaactccg actagggtaa cattgggaaa atccaaaccc
     7141 tttgcaatca tctgagtacc aagtaaaata tccgcttccc ctcgcccaaa ctggtcaagc
     7201 aaggcttggt gactgccttt ctttcgagtc gtatccacat ccatcctaaa aatgcgagct
     7261 tggggaaaga gttctgctag ctcatcataa gccttctgag ttcccgtccc atagtaacga
     7321 atactgtggc tcttacagtt aggacagacc tgaggaatat ccttcgagaa accacaataa
     7381 tggcagttca tagtcttggt atccatatgc aaggtcagag aaatatcgca gttgggacaa
     7441 gtatccaccg tcccacactc ccgacacatg acaaagctag aataaccacg gcgattgagc
     7501 atgagaacca cctgctcttt tttaaccaga cggtcttgga tagcctctag caaaggaggc
     7561 gtaaagtttg acgtctcatt ttgtccgata tagtctcgaa agtcaatcac ttgaacctca
     7621 gggattgtag ccaaaggatt ggcacgttgg gttagacgta agtgttgata gacgcctttg
     7681 ccagcacgtg cccggctctc taagctcggc gttgcagatc caagtaccag agttgcttga
     7741 ttatactgag cccgtaaaat agctacctct ctggcatggt aacggggatt gctgtcctgc
     7801 ttataagccg cttcatgctc ttcatcaata atcatgacac ccagattttt cagaggagca
     7861 aagatagcag atctggcacc aacaacaact tgggcatcgc cacgctccac cttgcgccat
     7921 tcatcatact tttcaccatt ggataatcct gagtgaagaa tggctacctt gtccccaaaa
     7981 cgtgctataa aacgctcggt catctgagga gtcaaggaaa tctcaggtac cagcaaaata
     8041 gctgtcttgc ccttatccag ggcaccttgg ataatctgca agtaaacctc ggtcttccca
     8101 cttcctgtaa tcccttgaag tagaaaggga ggttgagaac tgccaataga actcacaacc
     8161 gcatcacgcg cctgtctttg ttctggattt aactccaaag gtctacttgc ttcaattcct
     8221 tcaaaataag cagccgagcg ttgaacttcc ttttggacta tggtaacagc accttgatcc
     8281 acaaagaagt tgacttgctc tcgcgagtag gactctaaca agctagccaa ggaagcgctc
     8341 tctggatgag acagcagata atctctcagt tccaactttt tcttggcacg tgtagaaatc
     8401 tcaacacctt ctaattgggc atggtcaacc tcataccaag actgggtctt gaccttcttt
     8461 tgatcgactg cctgatattc cagaccaagc aggccttttc tagtcaaacg catcatttca
     8521 gcttgcttgg caaggtctag tgaagaaaag gctagcgaat cttctgaacc aaacaggcgt
     8581 actcgttctt cctgactcaa gccttccaga ggatagagaa tcttgtcata gctagaattc
     8641 agaaatcctg gaagcatggt cttgaggata gagattttgt aggagaagac agatttgcgt
     8701 aactcctcag ccagccagag ttgttctggc gtgagaacag gagaaaaatc cagcacctct
     8761 gcaatatctt ttaaatcttg ctccatctct tctccatctg attgggactc caaaccaaga
     8821 acaatccctt gaatcaggcg attaccctta ccaaaaggta catgaacccg catcccaact
     8881 tccagcattc cctcaaattc ctccggaatc ctgtaactat agggctggtc cgtctgcatc
     8941 aaaggcacat ctacgataat cttagctagg gccatcttct cacctcctcc ttgtcagtac
     9001 attcttgcaa tagaaaaaat aagattgagt ccccccaacc ttaaattttt tcaccatctt
     9061 ctttttcttt agcaatttgc tctttgattt tcttttcttc ttcttctttg cggcgtttct
     9121 cttcttcgat acggcgacgc actgcttcac gttttccttc tggatctggg tgaattgtaa
     9181 cgtttcctga ttcgatttct tctaaagcgc gaagagttga tttttcagac ttgaaacctt
     9241 gagttgctgg ggcacctgct tccaattcgt gggcacgttt tgcttccaag attacgagtg
     9301 aatattttga aggaaccttg tcgagcaagg tatcaataga gggttttaac atcatttgct
     9361 tgtacctatt ttctaaattt tatcgggtag ttggagattt tggtaacatc tcctgatagt
     9421 gaccaatgac acgatccaca cagaagtgtt ctgcttcaat cacacatttg acacgttcag
     9481 cagctagggg cacctgatcg ttgacaatcg cataatcata ctcacgcatg agggcaattt
     9541 cttccttggc cttttcgatt cgttgggcaa tcacttctgc actatctgtt ccacgaccta
     9601 ccaagcgatc ttgcaattca tccaaatctg gtggtgtcag gaagataaag acagcatctg
     9661 gaaccttttt cttgacctga agagcaccct gaacttcaat ttcaaggaaa acatcgattc
     9721 ccttgtccaa ggtttcattg acataggtca gaggagttcc atagtagttg ccgacatatt
     9781 ctgcgtattc caacatctgt ccttgacgaa tcagctcttc aaattcttca cgagtacgga
     9841 agaaatagtc aacaccgtcc acttctccag gacgttgtgc gcgtgtcgtc atcgatacag
     9901 aatattgaaa ttggttttca gaactctcaa aaatctctct tctaaccgtt ccttttccaa
     9961 cccctgaagg accagaaaaa acgattagta agcctcggtc tgccattgtg tctcctttta
    10021 gtcaatctgt gaaataacat ttctctagaa taatggcaaa aagccagatt atcctttaca
    10081 gtctttctat ctagtgtaac aaaaaagcag taatttttca actgctcttt cttatttatt
    10141 tagcataatc tactgcacga agctcgcgaa tcacggttac cttgatattt cctggataat
    10201 cgagattgtt ttcaattttc ttacgaactt tgtgagccaa gattgtgact ttgtcgtcct
    10261 tgatttttcc tggattgacc atgatacgaa tttcacgtcc tgcttgaagg gcaaagctag
    10321 tttgcactcc ttcaaagccg ttagcaattt cttccaaatc atggagacgc ttgatgtagc
    10381 tttcaagaga ctcactacga gcacctggac gggctgcgct caaggcatct gctgcagcga
    10441 cgataactgc tatcacgctc tcagcttcaa catctccgtg gtgactagca atcgtattca
    10501 ccacaactgg gggttccttg tacttacggg ccaattccat accgatttca acgtggctac
    10561 cttcaacctc atggtcaatg gctttcccga tatcgtgaag gaatccagca cgacgggcaa
    10621 gagccgcatt ttcaccaagt tcgctcgcca tgataccagc caacttagca acctcaatcg
    10681 aatggcgcaa aacattttgt ccatatgaag tacggaactg caaacgtccc ataatcttca
    10741 tcaagtctgg atgaaggttt ggcgcaccaa tttcataggc agcagcctca ccgtattcac
    10801 gaatcttatt gtcaatctct tgacggtttt tctcaaccaa ctcttcgata cgagctggat
    10861 gtatacgacc atctttgagc aacatttcca tagtcatacg ggcaatctca cgacgaatcg
    10921 gatcaaatcc tgacaaggtc accacttctg gtgtatcgtc gataatcaca tcgacccctg
    10981 tcaaactttc aaaggtacga atgttacgac cttcacgacc aataatgcgt cccttcatag
    11041 tatcgtctgg cagatgaact gttgagtttg ttgactccgc tacatattca ccagcgatac
    11101 gttgcatagc ttgaaccaag atatccttgg ccattttgtc agaacgttcc ttgacctctt
    11161 gctcagcttc gcgaatgcga ctggcaatct ccctggtcaa gttttcctct gtctgagcca
    11221 agataatatc tcgtgcttct gcctgagaca gagcaccaat acgctctagt tctgcttctt
    11281 tttgtctttc gacttcctct aattgctctt cacgcgcatc aaggtttttc gctctatcag
    11341 aaatactttg ttctttttgt tcaagtgttt gttctttact cgtcaaattg tcgtccttac
    11401 ggtcaaggct agtagctctc tctgtcaaac gactttcgat ttgtttgagt tcttgacgtt
    11461 ctgatttgaa ttcagcgtcc acttcttcac ggtattttct ggcttcttct ttggcctcca
    11521 atagtgcttc ttttttaaga gacttgcttt cacgtttagc ttcattaaca agtaaatccg
    11581 cttcacgctc agcttgtcca cgtaaattag ttgcttcttg ttcagcattt aaaagcatca
    11641 actccgcagc ttcctgagat gatttcatct tagctgagat gctgacatat ccaatgacta
    11701 aaccaatgat gacggcaaaa acagcaatcg caagcgacat gatctccatg tttttacctc
    11761 attttattgt tattccgaat gacatacatt cttttacatt ctaccataaa aaagtgattt
    11821 tcacaaacct aaaatagaat atgttttggg gaaattagtc tgaattttag gattacactt
    11881 ccttggtttt ttaaggagat aagtcagtgc cgctatcaaa aagttccacc gaatttctac
    11941 cgctatggat tttctattgt tgtgccaaat agtgttccac tagattcaaa cattttgctt
    12001 tcaagtcttt gaaaattcac tttaggaaat cacagcttat cttcaagatc aaatttgtca
    12061 taaattaact tttttattta gttgtatcaa tttatttctt aagtattaat ttatcctcat
    12121 cgaaagcttt taaaatatac tcattaatca atttattatc ttcttcattt tttgaaaaat
    12181 aagttttaat attattggga gttctatgtt ctagtagacg atggataaca tcatcacttc
    12241 tatcatggaa ccaggtccaa tctacttcag gataaagtcc tcgaatatct tcttcaatat
    12301 cttttaaaat ctcaaaatca gaaaaatatc cttttctact taagttgtat aaatctgata
    12361 cagacttttc tcttgggtct gggaaagttt taaccccctc aactctttta tcattaattc
    12421 ttttaatcaa ataatggtag attttatttt gtatctgagg aaaatcatag acattataac
    12481 tcatcaaatc aattacttta tggtaaataa tattttctga ttcttcataa acttttagag
    12541 tatctaaaat gtcatcttta atatcctttt caaaatactt aaataagtga catatcaagt
    12601 cagaatattc tatgatattt tttatatcat catttttata ttttattctt aaaatatctg
    12661 tattaaattt ttcgagtact attattgcag tttcctgatc agttgagcag tattctagta
    12721 actgtgaata gagcggatac actgaattat ataaagaaaa atttttctcc aaaatttcat
    12781 ttaaatgttt atttacaatc ccaattatct tagatttcaa tgaatcttta tcaataacat
    12841 ccatattatc gaggacaatt ttaataattc tcctaaattc ctcgctccaa ttataataca
    12901 gtgtttgatt atttaaaatt tctattactt tttctatgtc aatatcatca acaaggggaa
    12961 gaaaaattag catattttta agctctcgaa gattttcatc ttcagtaatt tcaagtcttt
    13021 cttgaagata agtaattcga ttcaacaagt agtctttcgc ttcctcagta acttttattt
    13081 taccaaatga atagtttcta aaatataaat ttacaacctt aaaatctata ttcggaagaa
    13141 ttaatttaac atcatccaaa tcaagatttt taagccaaga agatgttcta tcgaaaatac
    13201 ttgagtcagg gtttacatat gaattatcat aactgagtaa taatatttct aaatatctat
    13261 taatgattga tttataaatc ttataatgtt caacacataa acaatttaat tttaaaaagt
    13321 tataaagatt ttttactgta aactccgcat taaatagatg attattagca gaccatcctc
    13381 ctcttctata gctttcatgc tcttcacgaa tttcatcaaa taattcatta atagtttcta
    13441 attttctata taaaaaattg aagttaagga ttgaatctct aaaaaattct ataatctttt
    13501 tctcatctcc tgtaaccgag ttaagaattt gttctgttaa ttcgcttaat tctccatcat
    13561 aaagtggctc tgcataacta ggtgtttttt cgtatctatc aattatttga atttgctgaa
    13621 aattaaattc acaaactaag aaattaaaat agtctttctg acgaaatgct atattagcta
    13681 gttctctaaa ttttgctttt gctaaagaat attgtttttc ttcatacaac ttaaaagcct
    13741 tacttaagaa tcgattcccc tttaaatccc taggctcacc aatctccata tctagaaagc
    13801 gatttaataa agatttttta gataccataa ttcgtaattc ttcatgacca tcaatttcaa
    13861 atcttaattg atcatttcca aaccagcaat actcatcatc ccagtttaaa gcccttttct
    13921 ttaaatcaga atatctagaa aaatctttcg catcaataaa actaagtcta tctaaaaaag
    13981 ccagttgatt ccataaatca tcagcattat ttacatcttg acttcggttt tctgatagaa
    14041 cctctaaaaa atcttttgtc ctgcaataca atttgttctg tttttctgat gtctcctgac
    14101 ctagattctc ttcattagag ataatgaaaa ttccttgctt cttataatac tctcgaatga
    14161 tcatagacgg ttcctcggga gtataaaaat aagcattttt agcatccaat ttaaatgtat
    14221 tttgaatcat tctaaaaatt gaattaaaag tcgaatcact tagagaatac cccacaaaca
    14281 atagagtatg attcattatc aatgactgga ttaaagtaga aatcattggg aagttcaaat
    14341 gatagtctaa ataatcatct tctttcaaaa caatattttt cttactgaag tcaccatgca
    14401 ttttaatcaa gtatctttcc gaactcgtat aagggatgtc tttatcctca gcgactacat
    14461 tgtactttaa caagccactt tcaaattgac tctccagaag tgaatcatag tttgtcgtaa
    14521 taatatgttt tggtgcaatt ttttctatta atttatgtaa ctcatttggt ttactcaatc
    14581 ccttcttaaa gaaaatttct tctatcttct ttgtgtactg atttttccca aaagtatcat
    14641 aataatactg agcaattctc agtggactat ctgttctttc ttctggtatg ttcaattctt
    14701 tttttaatga ttgaatcaat tctccccaag ttggtagatt agaattagct gatattcctg
    14761 caccaacaaa caaaactaag gaattttctt taatagaatt ctttatttga gttatagata
    14821 aattataatt ttcttccata ttttaactat cctacattag cttgtactac ataaatacaa
    14881 attatcctta taaatcttct tttttattac ataatcttaa acaaaagttt atcatggttt
    14941 ataaatataa aaatttattt gtcttttata ttcaatttat gattattaat ataaccagtt
    15001 ctcttcatta taccacaaaa taacaagcat aaagcggatt caaagataaa gattaaggtt
    15061 catatactaa ttttctttat tgactttttg tcttctgtat tagggagttt atcattttcc
    15121 aaaaacttta tcttcaattt gttatctaaa atttctacaa taaaaaagcc tacctttcag
    15181 tagacttagt ttgtttctat tctaatcggc actctgccaa aattttgctc tgctatactt
    15241 ggctttccta gttggtaaat ctggtcaacc ttttgagtca tagcatccca aggttctttg
    15301 ccaattcggc tgactagatt gacctgtcct ttcagagact tgagatgttg cctgcctttt
    15361 tcagtaaatc caaggacatg aatggcttct ggcaagacat tttctctagc ctgtaccaaa
    15421 atataggtca ataggcgtct gacacgcgcc ttggtgtaac gtttggtagt cactaactcg
    15481 accaattctt ccacagactg ggctgtttta atagcttctt taatgcgcac agccatttct
    15541 tgattgacct gatagatggt ggttaggtcg ggatttgaca agatttgata gcggagcaag
    15601 ggaaaatagt cttcccagat caccttactg gcctgctcaa atagggcaac agaaggcata
    15661 aaacgttcta agaaatcttg gtccttctga tgttgacgga gggctgtcgc cgaggcaaag
    15721 tccacatctt tattcacaga atggtaacct gccccctgac gctgaatcgg atgcagcttg
    15781 atatttcgtc ctgcaaccgc ctttgcatag gccagagcaa gaacatgatt gggggtatta
    15841 cctgaaaaat caagaccagc aaattccttc cacatagctt gggttttctg gggataggaa
    15901 agggaatcag gcagattttt cacaaatttc tccatctcag cacctttctc tgtgtataag
    15961 tcagcgattt tctggtaatc cagaacttcc tctgtcccaa aaactagact atcaatgccc
    16021 aagcgatcca agatatccac agctccttga ccaaagaaat cagctgcctg aacactgact
    16081 aaaaagggca attccactac caagtctgcg ccattttcca gcgccatctg ggcccttgtc
    16141 cacttatcca caatagcagg ctctccacgc tgcatgaaat tccctgacat ggcaacaatt
    16201 ttcagtccct ctgcctgatc cagcaggtat ttatggccat tatgaaaagg attgaactcc
    16261 gcgataatac ctgttatggt catgctaatc tcctacttct gcgccacaaa aaaccaacgg
    16321 gtgctagttt ctgttggctc cttatcctca aagtctgcat agagtttgaa ggacttgaat
    16381 ccagcctgtt ccagcaagat ctcataggtc aagatctcat aggtcctctc ctcatgtact
    16441 tcatcgtggc gactaaagga accatcagcc tccttgataa agaaagtcag ctcatggacg
    16501 atggagtgag gaacttcgtc ctcatatgta tcccaaagca tggcaaaatc ttccgcattt
    16561 tcatggtagg aatagccagg gaatacttca tctgtctggt aggtcgagtg cacgtcaaag
    16621 atgaaaactc cctcttcatt cagcgcattg tacacgtcct taaagacgtc ccctacttcc
    16681 acctcatcct gcatatagca gatagagtcc gaataacacg tgacaaaatc gtatttccct
    16741 gccttggaca aattcagcat attaccttct ataaaagcaa tcttttgctt ggctgaagtt
    16801 gctctcttct ccgcaatctt caacatatcc gcactcaagt caagtccagt cacatcaaaa
    16861 ccagcctgag agaagcgcac tgattgaatt cctgtcccac aagccaattc caagagtttc
    16921 tttctctcct tggtcttagg caaatgacgc agagaaaaat tcgtccattt gtcgtataaa
    16981 ctatcgtcca tgaccgcatc atagaccgcc gcaaaggttt cataagtcgc cataatcatg
    17041 atactaagag ctccatggta aacaccacta gccctttacc tttctatcaa tttttctaaa
    17101 ataagcaaag aaacccagtt gactacaact gagttcatct tctaagcaag agcttctgaa
    17161 atatctactg aattcgcctc atgccatagc ttctctagat tataatgggc acgcatttct
    17221 tctgaaaaga tatgcacgac aacagcaccg aggtccagta agacccagcc tccagctgca
    17281 tcgccttcga tatggctacc tttaaagcct gcttgagcta ctttttcacg gatattagct
    17341 gcgatagcgt ccaactgacg gctattcatt gagctagtga tgacaaagta gtccgtcaca
    17401 ctagtcaaat cttgtacatc aagtgcgagg atatcctccg cacgtttctc atcagccgct
    17461 ttcacgacta gttctagtaa ttctttttcg ttcatttaat cctcttttta gaaaatatgt
    17521 ttgtaatcta gaacatctgc aaagcactcc tcccaaatgt cctcataaaa ttcattaatc
    17581 gtttctgctg gaatgtcatc cccatcaaag gttgtgacag caccttctgg aacaataagc
    17641 tgatagccat attcaaaggc aaccttgaca gaggtatcca cacaatattc tgtctgcata
    17701 ccacataaaa ctaatttttc aatcccctgt ttatccaagt attcttttaa gccagtttct
    17761 ttgaaaatac tgttatactt cttctgaaag accttttcag caggttttcg atttaaaagc
    17821 gcagataact gccaatcttc tgatgtttga gcttcagaat tctcaatatg ttgaacatag
    17881 ataatttcaa tattcttgct tctagcctgg ttttgtaaat aagaaatttt ttccaataga
    17941 ctttttgtct ggaacccagt ttctactaaa acattctgaa catcaatgat tataaaagcc
    18001 gtcttcattt agtcctcttt caaatagtgc acaaaggcgt tataggtttc aagggtttgg
    18061 ggatagatgg ggaatccctg atgagctaga tactccacgg tacgagctgt ttcgtaggcc
    18121 accgccttat tgagcgatag acttgcaatc tcacgcgcca catctactcc aggaaaggct
    18181 cgattgtgct cgatatagtc tgcgacgtag atgaccttat ctaggtctgt catttgacca
    18241 gcaccgactg tatggacttc aatggctcgc aggatttctg aatcatgcaa atccaaatct
    18301 tcctgaattt tgtaaattcc gaccatacca tgccagacat tattacccca gtttttgagg
    18361 tcgaaatcta gctgataacg gtcaatcaag tctagaaatt cctgatctga caacttttta
    18421 gcatagtcat gaagaagacc tgctagactt gctttctcaa catctacacc aaagcgctga
    18481 gctaactcca tagcggcacg ctccacacct agacaatggg ttagacgttt ctcaggtaga
    18541 agctctgcca ttttttccaa caaggcctca cgggagcagt tgatatagtc ttgataggac
    18601 atcagtagag cccctccttc tcgatgtagt ctagcactgg ctgaggtagg agaaagttgg
    18661 gtttccgacc ttgggcaatg aagtcccgca ccatgctgga cgagatatcc atgagcggta
    18721 cgtccaccca gataactgga taggaagtcc ctgccttgta gcgtggacgc tgaaccccca
    18781 caaactgaac catgtcaacc agttcatcaa ttcggtacca cttaggcaga tagtcaacca
    18841 tgtcggcacc gatgataaag taataatccg tatctggatg ttgctctgtc aagattttca
    18901 tggtgtcgta ggtgtaggaa atacccttgc gctccaactc aatggtttca atgactaggc
    18961 cgtcaatccc ctcaattgcc aactcaagca tcttgagacg atggtgttca gggatggttt
    19021 cctttttatc aacgtgagga ggttggtatt caggcatgag aagaacttga tccagtccca
    19081 actgttgccg tacttgatcc gcaacaatga gatgggcatt gtgaacaggg ttaaaattcc
    19141 cccctaaaat cccaacttgt ttgcgttttt tctccttgat ttctggctcc aactctacct
    19201 tggtaaaggg agtcaatagt tcgattgtca taggctagtc ccctttattt ctctataaaa
    19261 acagttattt ggagtttcgg tcttagattt ctttgacttt cttagaaatc ttgcgatttt
    19321 ctttcttgct agattgttta aacaaaatca agatgcgtcc tattttttgg actgtatcca
    19381 caccgatttc ttcttccaaa atttcagcta cttcgtggat attttcatct gtgttttgta
    19441 agagagtaac cttgattaat tcacgcgcat caagagcttg acggacgctg gttttgattt
    19501 ggtcgttgag tccatttttc ccgatttgga tgataggttt gagggtgtgt gcctggctgt
    19561 tgaggaaggc acgttgtttt gatgttaatg acataatttt cttccttgtt tttggatagt
    19621 tattttaggt ggtgagggac ggtcggaact aattttccaa agatttcatc tttgaaaaat
    19681 ggatttcctg acctcacaat tgagccttgg tctcaattgt gccccttgcc aatctacaga
    19741 ttggcaatca caccacggca ataactatcg ctatatgagc tcactttgtt cgctcagcga
    19801 ttttgtttta aataattgct tttcgtgtga cgacggcgac gccttctggt gcccagacgg
    19861 cgacttttgc tatgcctgtt acacgaatcc agcctaggcc tgagatgact aggtctgtct
    19921 tatctttaat ggtaaagaca tgctggacta gccttgggaa atcttctttt tccttgctat
    19981 ttggtggtgt cagaagagtt cccaggtgct tatcgtagaa agcactagct ccttcaaact
    20041 tgctacgatg gagtttgagt tcattatcaa agaaagcagt aaatccttgc ttttctcctg
    20101 ctataaagtc aaagcgtccc aaaccaccta aaaatagggt ttgctcagga ttaagctgat
    20161 aggtcttagg cttgatttcc tttttaggac tgacatactt gaggtttttg gccgtcaagt
    20221 agtgagccat ctggtggcgg tggataattc ccggcgtatc gtaaatataa gatccgtcgt
    20281 caagcggaat ctctattttg tccaaggttg tacctgggaa gcgtgaagta gtgatgacat
    20341 tctgatcacc cgtgatttct tggataatag cattgattag agttgatttt ccaacgttgg
    20401 tcacaccgac cacatagaca tcgcggccct tacggtagtg ttcaatcttg tcaatgactt
    20461 ccttaatggc atgtttattt tgtgctgaag ttaggaccac atcgactgga cgaagacctt
    20521 cttcatgggc acgtttcatg agccactggc taatcttacc agacttaact gacttaggaa
    20581 ggatatcttt tttatttcct accaagagga catcattgcc cgagacgaaa cgtggtaaac
    20641 ctgggatgac agatccatta aaatcaaaga tatcaatgac attgaccact aaggcatcac
    20701 tgtctcccac ctcgtgcaag agcttgagga aatcatcgtt cgtcaactgg acatctgtga
    20761 tttcattgta gtggcggaga cggaaacagc gttggcaata gacttcgcca gtctccaaac
    20821 ctttttcaag tgccgactgg ggggtaaaac caagaccagc tttatctgtc gtctgaatgg
    20881 ttgctccaca accaatacag agaatttctt ccatagttaa attccttttt tatatgtaat
    20941 cggtccgtac ttttcagtga tttttctcat aacacgacgc tcacgagttc ggttaatctg
    21001 cgttttgatt gagtcatgtt ggaccaaggg tttgactaaa attgaccgaa tccctgcacg
    21061 gtgggctgct cgtatatctg tcatgagctg gtcgccaacc atgaccactt cctttttgtc
    21121 atagtggaat tccttcatag cacggtcaat accaaatgtg aagggcttca aggcccagta
    21181 aacgtaatca atcccaaatt tctcaactgc tcgttgaacg cgttttttgg tgttatttga
    21241 cactacgata atgccaatac ccgcgtcccg aaggtcatgt agccattgct tcatctctgg
    21301 cgttccatca gggttgttcc aagcaatgag ggtattatcc aaatcgacca aaacagcctt
    21361 gattccctgc gcctgcaggc ttgggactgt cagatcatag actgcttcca cagcaaaatc
    21421 tggtatataa ttttcaatcg ccattctggc tccttttctt aacttttttt cgcaattttc
    21481 cttagtaaca aggataaaac aatccacaaa cctgcactag ccaaactgat atagagccaa
    21541 gcatggggct catctgttaa aggtaaggga acattcattc cgaaaaagcc tgtcacgact
    21601 gccaaaacag ctagcaagac tgaaatgata gtcaaggttg tcaaattgtc attcagatta
    21661 ttgtttagaa tattgttgta agaggctgaa agctgctgta aaatctgaga gattaggtct
    21721 gtcatggata ccagctgatg agcctcaatc atggcatcat caaactgttc tctctcaatc
    21781 tcatcaaaac tacgatacaa ggcatgacct tgaatatgct ctaacaaaat ccgattttgt
    21841 ttggcagctg ccgtcagata aaccatacca gtctccaaat cagacagggc aaagaggttt
    21901 ttcttggtag ttcgctggcg caagaggtca ttgacctcat ccctactctt gtccatctgc
    21961 tcaatgacag gatagtaggc attgctgata atttccagac tggcaaagag aaacttataa
    22021 atcgaaagcg tgtcatggct ctccagataa cgagtcatct gttcaatgac ataggcgttc
    22081 ttggtattac taatggtaat caggcgacga tgctcgacaa taaaggtcat gggaaaagtc
    22141 tcatagtagg ccttgtcctt ttttacgtct aggacattat agataaaggt aaccgtccca
    22201 ctttcacggt ggtaatccat gtgggcgcgc tcgtttctat ccagtgcgta ttcaatggtt
    22261 tccttgtcca aaccgtaaat ttcagaaagg tcttctagtt tattcaactt tcctaggtct
    22321 aggtctatcc aggtacaacc attgcccaac tgcttttcta aaaccatctt ttctccttat
    22381 taaactccct ctattgtacc acaaattact taaaataaca ggtctagtct gtgcgtgaga
    22441 aattgctaac aactgtgata tttcggttag ggacaaagtg aagggcttgc tcctcgctac
    22501 gaagctgtgt cgtacgaatt cccacactga caaccttacc cgatacagta atcggtccat
    22561 ttgtcagaac gacctcatct cccacatcca gttgacgttc aaagaggatg aaaaagccat
    22621 tgatgacatc agacagaaag ccttgggctc ccataccaat cgctacccca gcaataccag
    22681 ctccagccag caaactagaa actggcaaac ctaaaatcga caaaatgcag tagagtaaaa
    22741 agaaatatag cgtataatta aacacatttt ctagtaaacg tgagatggtt ttttggcgtc
    22801 cgacatcatg acgagacatt tttagagaag gtttgacaat tctctgcacc atggtatgaa
    22861 gcattttttt agcaatataa aatacaatca aaagcagtaa aagagaaatg accttggtta
    22921 gaatattctc gataatggtt gtcacatcta gcttttcaat ataagcctga ataaattttt
    22981 gcatataaaa ctcctttatt tcattatacc atattttcat cagtctcatt ctccataaat
    23041 attcaaaaaa cagacagaaa attcttgatt ttgtctatca tttatactat aatcataatc
    23101 actacacaaa aaggagatta ttatgaaaag aatcattcat gcttggaata aggcaagcct
    23161 tgtcaagcgt atcttgattg gtatgctttg tggggaatcc taggactgac ccttcctaat
    23221 ctctcaggga ttgggctact cggggattta ttcgttggag gtctaaaagc tgttgctcct
    23281 atcctagtct ttgccctcgt tgccaatgcc ctttccaaca tcaaaaggga caagatagca
    23341 atatgaaaac tgttgttttc ttgtatatcc tatgataggg actttcgccg ctgctcttgt
    23401 agctgtacta gcaagtttca tcgtccctat tgaaattacc ctaaatagtg ccaatactga
    23461 aattgcacca ccagatggga ttgggcaggt cctcagcaac ctcttgctca aactggttga
    23521 caacccagtc aacgccctgc ttactgctaa ctatattaga atcttatctt gggcagtcat
    23581 ttttggaatc gctatgagag aagccagtaa aaatagtaaa gaattgctaa aaactatcgc
    23641 tgacgtgact tctaaaattg tcgaatggat catcaatctg gctccatttg gaatccttgg
    23701 tcttgttttt aaaaccattt ctgacaaggg agtcggaagc cttgccaact acggtatttt
    23761 attggttcta ttagtaacga ctatgctttt tgttgcccct gtggtcaacc ctttgattgc
    23821 cttcttcttt atgagacgca atccttaccc tctagtttgg aactgcctcc gtgtcagcgg
    23881 tgtgacagcc tttttcactc gtagttctgc gactaacatt cctgtcaaca tgaaactctg
    23941 ccatgacctt ggactcaacc cagataccta ttctgtttct atcccactcg gttctactat
    24001 caatatggct ggagtagcga ttaccattaa cgttttgacc cttgttacag ttaacactct
    24061 tggaattcct gttgactttg ccacagcctt tgtcctcagt gtggtagcag ctatctcagc
    24121 ctgtgatgct tcaggtattg ccggaggttc cctccttctt atcccagttg cttgtagcct
    24181 tttcggtatt tctaacgata ttgccataca aattgttggg gttggttttg tgattggtgt
    24241 catccaagac tcatgtgaaa cagcccttaa ctcttctaca gatgtcctct ttaccgccgt
    24301 tgccgaatac gcagcaaccc gtaaaaaata actcatcaag gcaagcctgc tcatgtcttg
    24361 tcttttacgc ttttattcta acttattagg aaattcttat gtctattagc caacgtacga
    24421 ccaagctcat cttagctacc tgtcttgcct gcctgcttgc ttattttctc aatctttcgt
    24481 cagcagtttc ggctggaatt atcgctctct tgagcctatc tgatacgcgt agaagtactt
    24541 taaaactggc tcgcaatcgt cttttttcta tgcttctagc tctggctatc ggcgttctag
    24601 cttttcactt gagcggattt catatctgga gtctcggcct ctatctggcc ttctacgttc
    24661 ctttagccta caagatgggc tgggaaattg gcatcacacc aagcacggtt ttggttagcc
    24721 atctcttggt tcaagagtca acctctccag acctcctagt caacgaattc cttctctttg
    24781 ctattggtac aggatttgcc ttgcttgtta atctctatat gccttcacga gaagaggaaa
    24841 tccagcacta ccacacgctg gtggaagaaa agttaaaaga tatcctccag cgcttcaaat
    24901 actatttatc cagaggagac ggacgcaacc gagcacagct ggtagcagaa ttagacacgc
    24961 ttttgaaaga agccctcaga ctggtctatt tggatcactc tgaccacctc tttcaccaga
    25021 ccgactacca tatccactac tttgagatga gacaacgaca aagtcgtatc ctgagaaaca
    25081 tggcccaaca gattaacact tgtcaccttg ccgccagtga aagcctgatc ttagcgcaac
    25141 tcttttcaaa aattgcaggt caactgagcc agaccaatcc tgcttctgat ttgctagatg
    25201 aaattgaacg ttatctggaa gtcttccgga accgcagtct gcccaagaca agagaagagt
    25261 ttgaaacccg cgccactctt cttcaactcc tacgtgaagc caaaaccttc atccaagtaa
    25321 aagttgattt ttaccaaaaa tatagacagt aaaaaagaaa accactaaaa aacagagctt
    25381 gccagtattc ttgaaaagta gtataattat tgcatgcgca atcatcttgt gacgcagaga
    25441 ctgcccgtta atggactttc ttctatttat gactctaaaa agaaaggaga cactatgacc
    25501 tatttggaaa aatggtttga cttcaatcgg cgtcagaaag aaattgaaag tctcttggaa
    25561 gagaccattg cccaacagag cgagcaaagt ctgaccttga aagagttcta cctgctctac
    25621 tatctggact tggctgaaga aaaatctcta cgccagattg acctgccaga taagcttcat
    25681 ctgagcccga gcgcagtttc taggatggtg gctcgcttgg aagctaaaaa ttgcggtcta
    25741 ctcagtcgca tgtgttgcca tcaagataga cgctctagtt ttatctgcct gacaaatgat
    25801 gggcaaaaga cactggcctc gctacaaaag actgtcgaag aaagcttgga agcaggtttg
    25861 gatttcttga tttaagatga ttttaaaaaa agttgcgtgc gcaatcattt ttcttgacat
    25921 tctcttttat aaggagtaaa ataaagttag cattaaacaa aggagtttta aatatgattg
    25981 aaattaccta tatagatgcc agcaagaacg aaagaactgt gactttcgag tcttatgaag
    26041 actttgaacg ttcgcaacaa gcttgcctta tcggcgtcgc agactactac cctgtccaaa
    26101 aattaactta caagggtcat aatttggact accatgggac ttatggagat atcttcttct
    26161 atctcatgaa acaagattta agccaatata actaaaaaaa ggagaaatac aatggcaaaa
    26221 gcaattacag atgcaacatt cgaacaagaa acaaaagacg gtttggtctt agtagacttc
    26281 tgggcaactt ggtgtggtcc atgtcgtatg caaggtccaa tcttggacaa attgtctgaa
    26341 gaactttcag aagatgtctt gaaaatcgtt aaaatggacg ttgatgaaaa tccaaacaca
    26401 gctcgtgctt ttggaatcat gtctattcca actcttctct tcaaaaaaga cggccaagtt
    26461 gtcaaacaag ttgcaggtgt tcacacagca gaacaaatca aggccatcat tgctgaattg
    26521 agctaatcaa acgagagacc aagtactttc tttggtctct tttttcttgc tctttgccat
    26581 ttttcaaaaa atatgctaga ctatagtaga ttgaaactag aatagtacac ctctacttct
    26641 aaaacattgt tagaaatcga tttgactgtc ctgatcgatt tgtcctgttc ttatttcatt
    26701 ttactatata agtagaatat tacgatgttt gggatatgcc atcgctaaaa aaactcgatt
    26761 tggtattttt tagctcccta atgggagctt tttgcgtgct ctgaacattt cccattttgg
    26821 aaggagtact atgaaacgtc aatcagcctt ggtcgtcttt agtggtggtc aagattcaac
    26881 aacctgcctt ttctgggcca tgcaacacta tgaaacagtc gaagctgtca cctttgccta
    26941 cggccaacgt catcacctcg aaattcaaat tactagagaa atcgctaagg aacagggcat
    27001 tcgtcaccat atcctcgata tgtctctgct gggacaaatc actgctcagc cagactttgc
    27061 gacgattcat atttcctaca ttcctgacaa gctctgtgtc gagtcaaaat ccctcaaact
    27121 atatctattt agctaccgaa atcacggaga tttccacgaa aactgtatca acaccatcgg
    27181 gaaagacttg gtcaacttgc tagaccctcg ctatttagaa gtctggggaa aattcactcc
    27241 gcgcggtggc atttcaatcg acccctacta taactacggt aagcaaggaa ctaagtatga
    27301 gggcttggca gaacaacgcc tcttccaaca cgacctttat ccagagaaaa ttgacaaccg
    27361 ctaaagtcat actcaatgaa aatcaaagag caaactagga agttagccgc aggttactca
    27421 aagcagtgtt tgaggtggca gatagaactg acgaagtcag cttaaaacac tgttttgagg
    27481 ttgcagatag aactgacgaa gtcagtaacc atacctagga caaggtgaag ctgacgtggt
    27541 ttgaagagat tttcgaagag tatcatacga aaaagccctg ttcctcaaga tgaggagcaa
    27601 ggctttttga gtttcaatta ttcttctgtt ccaaggaaat tttttgcaac aagggctgca
    27661 agaactccac cagcgattgg tgcaaggatg aaaatccaaa cttgttgaag ggctgcgccg
    27721 cctaccaaga cagctggtgc caagctacga gctgggttta ctgaaagtcc agtaatcttc
    27781 aatccgacaa gaatcatcgc catcaatgac aaaccgatta ccaaaccagc aatcgcgcca
    27841 ttgcccttac tttctgaagt cacagtcatg ataactaaga caaacaagaa agttgcgatg
    27901 acttcaaaca agaaaccacc aaagacagtg acaccgtttg ccaaggcatt ttcaccaaga
    27961 ctagcagttg acatacctga attacccaag aggaagaaga ctgcgccaga agcgatgaaa
    28021 gctccaacaa cctgaccaag gatgtagttt acaagttctg aagatgacaa acgtttgttt
    28081 acaaacatag caatcgaaac agccggattc aagtgagcac ctgaaacagt tccgattgag
    28141 taggctgcca ccacgattgc caaaccaaag gcaaaggcga ttccaaggtg accaaggcca
    28201 tcaagaccat ttccaaaaac aacagctcct gtcccgacga atacaagcat gaacgtaccg
    28261 attaactcag caacaaattt tttcattttc tttctccttt tttcaaaaac tagatactag
    28321 tctatcaaaa gtaggaaagg gtttcaagaa aattgattgg aaattttttg aaaatcatag
    28381 aactattagc taatctctag tattgaaaag actggatagc ttctttcaac tcatcttgta
    28441 aactatttct ctggtcaagt tggacataga cttccaacag acaggttctg aagttggaaa
    28501 atttgtaaaa atcctccctt tcttctatcg gaaaatcaac agtttttatc caagaagcta
    28561 cttgttcttg cgctaacttc ccttgtaaaa taggttcata gatcactctt gctaaacgcc
    28621 aatcctcatc atctgtaaag cgaatcgaca ttcttttaaa tagttggcca agtatatcaa
    28681 atacttcatg aactctgttt ttaggaaagt ctggatgaca aaccacctct ttcagtaaat
    28741 cggctccatg tgcaaaagcg tgaacccaac catactgact tgagaaacct gttgtatcct
    28801 tttcttttga aagatagtgc aagccttgat ttaaaaggac attacgaatt tctgattgta
    28861 atccctgata aaaaaccgat tgctggttag catctacaga caagagattt gcataaacaa
    28921 gtgccctaaa agaacgttca agtgttgaca agcctacctt atcaatctct ttatctaacc
    28981 ctccatcagc taagaccacc tcagcaatga aatgaaattg ctcctgtgta aatagctctt
    29041 cctgaatccc tctagcaaag cttgtaaaaa caagatcatc acgaatttct ggagaaggat
    29101 ctcccaaatg atcaagcaac cactggattt cctcctggtt ataatttggt ttttcttctg
    29161 ctatttttct tagtaaatct tgatacatgg tcaatacctc tacatttcta gcaactgttc
    29221 aaaaaggcag tcttaaatga ccttaccaat ttgtaaaatt aagttaaaaa gaaaaagaca
    29281 tttatattca gagaaacagc atatttctga aaagatatat aaatgattta ttccatatta
    29341 caacaaataa acttgtaatg atagaacctt atcacaaaaa tcacattcct gtctcaaaaa
    29401 ttgcgaaaaa ctagttataa taaagtgaaa taaaaactat acaaattgat tagggaattt
    29461 aaaacaattt ctaacaatat ttaaaaactg aaccgtacta tttcaacttc cataaattac
    29521 aatattgata ggcacagttc ccatacctgt ccaaattcga ataacgttta gtataaatta
    29581 gaatatgact acaacatcac aaataattag actatctata atatctacga tgtaacatat
    29641 acataggaag caccgttatc aagagcgcca aggctatcaa ccagataaga tgaagataca
    29701 aacctgtcac ctcacctccc catataatac gaatcatgcg ggtagcgtga tacaagggag
    29761 aaaaccaagt caaatcacca agtattgggg gcaaggaagt aatgggaaag aaggtatctg
    29821 aaaacatata aagaggacgg attaccaaaa cattgtagta attcagaaat tccctagacg
    29881 gcgccaagta ggtaaagatt agtcccaaaa caccaaacaa ataacccact ataaataaaa
    29941 tcagaggaat caataacatc aagacatgaa aatgcgctgt gataagcatg gaaatcagcc
    30001 aaaaaatccc accgaaaatc actgcacgaa tacctgccca gatagcctga cctaccacaa
    30061 tatcattcgt attgattggc gtcatcaaca tagcatcata agtcttttca atcttatact
    30121 ggataaaggc attgaccgtt gtttctgcgg tggccgcaga catggcagtc gcagcaatta
    30181 aacctgtaat gacaaaatca cggtagagca taccgttaac atgcgtcaaa taagcaccaa
    30241 ctccaaatcc cattgctaaa agataaaaga gggggtcgat aaggttgggg acaattgaaa
    30301 ttttaaataa atttctaaaa ctcatgtagt tgcgtaccac aacgtgtccg atggagtgaa
    30361 atgataactt aaacatgcaa gtcctccttc tctgtcccag tcaaccccca aaaaagcgtc
    30421 tcaaggttgt cagcatcata cttgatgagc aagtcttcta cagttccttc ttctttgata
    30481 gtcccttggt ggagcatcag caccctatct gtcaaatatt caatctcatt catatagtgg
    30541 gaagtaataa tgatagaaac acctaattcc ttcaattcca aaagtttatc ccaaataata
    30601 ttgcgggatt gaatgtctaa accaactgtc ggttcatcta aaatgataat atcaggccga
    30661 ttgatgagag ctcttgccaa gacaagacgt cgtcgcatcc cacccgacag ctgattcacc
    30721 atcttttgcg catgtttgct cagttgaaca aaatccaaga gagaatcgat tctcttccta
    30781 agttcgacag atgagatacc ataacataga ccgtgagcaa aaagattatc ataaacattc
    30841 aaggtcatgt ccagcatatc ctcctgccct acaataccca gacaagattt actcttacga
    30901 cgattggttt caatattttg ccccaagata tcaatctctc ctgaggaaat tgaggtcagt
    30961 gagtaaatca tctttaaagt ggatgttttg ccagcaccgt tgattcccaa gatacccaaa
    31021 cactctccgt ctcccaattc aaagctaatt cccttgacag cttcataaga accatattgc
    31081 ttttttagat ttttaacact taacttcttc actctttctt tcccccacaa atagagcatg
    31141 ttggatactt tgttaattca tctcactttt gaaaaaatgt tgagaatgta atcttaagat
    31201 taacgtcctt caactgtgga tactgctgca attacttttg taattttacc tccatttaaa
    31261 ctcagacaat aaaatttaaa atattctcta gtaaaacatt tttaaaatct atttttcttg
    31321 tgctttaatt atagtataat aaaagataga aaatcatcga tatatgaaat ttggagaaaa
    31381 tttttatgaa accagatatt ttcatcatca caaaactctt atcagaccct tctcggatgc
    31441 acattttaga tattctaatg gatggaaaag ctcacacggt taacgaaatt gccagcttta
    31501 ccaaaatcaa gcaacatact gtcagctatc acctcaaatt acttaccgaa gcgcaggtaa
    31561 ccactctaca aacctatgga cgttttcatt attattcttt aaaaagtgct gccattgcag
    31621 aaatgctgga atttctcagc ttctactctc ctcagcgtga tgtcaaaagt tataaacaac
    31681 acattcacaa aaaggaatta aaggtcgctc gcacctgcta tgaccatatt gctggtgagc
    31741 ttggcatttc cattaccaat tatctcttgc aagaaaatct cctcagcgaa tcagaaaaag
    31801 acttccaact cactgaagct gggaagtctt atttccaaag aaaattacac attgatacgg
    31861 atgaattgaa aaagaaaaaa cggaaatttt gccctaaatg tttggattgg agcgaacgta
    31921 aaaatcatgt cggcggagct ctcggcaatg ctcttttaga atttttcagt gaaaaacaat
    31981 tggtcatccc tgcacaaacg ccacgttcac ttaccattac agagaagggc aaagaattcc
    32041 tcgaaaagga atgggggatt taaacatgga cttttaagca aataactgtc catacccatt
    32101 ctataacaac ctctctatcc ccttactccc ccaactcagc actgtaggcg ataatctggt
    32161 caactgtgtc agacaagaat tggatggtat cacggagtgg tttgtctgtt gaaatatcag
    32221 caccgataat catggctgac tcaagtggtg tcttgctacc acctgatttg aggagattga
    32281 gccagtcttc agctccagtt tctgagtttt taagatgaag gtaaccagct gtcgagatga
    32341 caagaccagc agagtaagtg taactataca agcccatata gtagtgagct tggcgcatcc
    32401 aagtcaaagc tgcatcgtcg tcgatttcaa tggcatcgcc ccaaaaatct gtcaaaactt
    32461 ccttcataat gctgttgagt ttgcttgctc cgaaggtttc tccttcttca atcaatgtat
    32521 acaccttacg ctggaaggcg gcttccaaga ggtgggtgat gaaattatgg aagtaggtgt
    32581 ctgtcaagcg atgagccaga gcgaagcgtt tttgacgtgg gtcattagac tggttctcta
    32641 agtaatcact gagtagcaat tcattgaagg tcgacggtgc ttcaacataa taggtcgaca
    32701 tgtgggcgtt gaaatagctt tggtgattgt ctgaaaagat gaattgacca gaatgcccga
    32761 tttcatgaat caaggtatag acatcgctca aacggcctgt ccagctcatg agtacataag
    32821 ggtgtacgcg atatgggtcc gccgcataac caccggaatc cttgccactg ttagcagcaa
    32881 agtccaccca gcgctcttct tggtaacgag caacttcctg acaatattct tgccccaaag
    32941 gttctaccga cttcatgacc aaatcatagg catcgtcaat agtcacttca ggattgaggg
    33001 cgctgtccaa gtccaatttc cagtctgcaa aggtcatctt ttcaagacca tttaccttgg
    33061 caacatgctt gaggtatctc tgagcgactg gtgcaaagtc cttcatgatg aggtcaatct
    33121 ggcgatcaaa catgacacgg tccacttctt gttcagctag aagatagtca aagacagagt
    33181 catatccctt catatcagcc aagagttttt cagacttgac ctgagccaga taggctgctg
    33241 cagccgtatt ttggtgctta cgaagtccct ctgagaagga acggaaggat ttctcacgaa
    33301 cctcagcatc ctcgtgattt tggtagaaat tctcataggt gacaaagctg tttttatagg
    33361 tcttgccatg ggcttcaaag tcagccattt caaaatcccc agctcgcatc ttagtataaa
    33421 tgtcctgcgg actatagaaa acttcaccga gatttgtcaa ggccttctcc acatctgccc
    33481 ctaagtagtg ggcttttttg attttagcct gacgaatggc agctgttaaa tgtggcaatt
    33541 tacccaaacg gtccaagact tcctcgtctg ctgccaccaa ggcatcgtca aagaaggtca
    33601 aggctacgct ggcagctgtt tcaaattcca tcccagcttg ggcaatattg gcaaattcgt
    33661 cattgctata gtccgtcgtc tgaggcataa aagcatagtt gccaatatgg ctcatctgaa
    33721 tgtagatctg ttccaattcc gcaaaggcct tctcgaaatc ctcaaaagtg tgaagattgc
    33781 ccttgtaatc acggctaaac tggttgatgt cttcgcgagc tttctcgatt gcacgcaaga
    33841 aatcctcacg gtcttggtat agggctgtta agtcccagag ttccttctct ggaaattctg
    33901 aacggtgttt ttgttccatt ttcttcctct tatttctcta attctactaa aacactaagg
    33961 gctgataagg cgtaaagcgg tgctgtttct gctcgcaaaa tacgaggacc taggcctacc
    34021 aaaacggctc ccttagcttc aaaactttcg atttctgcag gtgagagacc gccttctgga
    34081 ccaaagataa agagcagttt ggctcctgtt tcaagaccag tgactgcttg cagaagcgca
    34141 gcggcttctc cttctttacc tgattcttca taggctacta tgatagagtc aaactggtcc
    34201 agctgagtta gaaaatctgc ttttttctcg aaaagtttaa tacttggtac aatattacgc
    34261 ttgctttgct cggctgctcc aagggcaatt ttttctagtt tttcaacttt tttacccaat
    34321 ttcttgccat cccacttggc aactgaccag tctgcaggaa aggcccagat ttggctagca
    34381 cccagttcgg ttactttttg agcgatgaac tccagcttgt ctcccttggg aaatccagat
    34441 gcgatggtca cttgaactgg tagttccaca ttgtcattta attcttggac caactcaaac
    34501 tgacgatttt ccatatccag cacgcgcgcc aagcgcttga tgccatcatc aaagactaag
    34561 gtaacctcat cctcttcttt caagcgcata acctgaaaca tatgcttact ggtttccttg
    34621 ttctcgatag tgacaggaga gatagcactg ccttttacaa aatactgctg catgctagcc
    34681 tccaatcaca ccagagatat ccttggtttt cttaaagaca caggcattcc attccccttg
    34741 aaccatgtga gtttcgagga aaaatccagc tgattcagcc aactcgcgca ccatgtccca
    34801 cttatccttg ataatgccac tcatgatcag gtaaccttca tccttaacca agcgataagc
    34861 atcctctgtc agatgaatga ggatatccgc caagatgttt gccacgatga catctgcttc
    34921 aatctccacg cctttaagca aatcgcctgc cgctacatgg atattttcca ttccagggtt
    34981 gagctcaata ttttcctgag ccacacgaac tgccacatca tccaggtcat aggcgaaaat
    35041 ttctttagcc cccagaagcg agctggcaat agagagaacc cctgaaccag ttcccacatc
    35101 tagcaccgtt tcgccaccac gaagaacctg ttccaaggca aaaatgctca tcttggtagt
    35161 tgggtgggtt cccgtaccaa aagccatgcc aggatccagc ttgataattt tttctcccgc
    35221 agtcgcctca tagtctgtcc aagagggaac gatggtcaaa tcatgagtga tacgagctgg
    35281 ctcatagtat ttcttccagt tatctgccca gtcttcctca gccaaggcag tcgtacctat
    35341 ttttaactct cccaaatcca taaaatccgt caattctgat atgcgagcct gcaagtccgc
    35401 ctcaaccact gtcacatcca ccgtgtcagg gtagtaggct gtcactacga tttcttcttg
    35461 ctgctcgacc tctgggaaaa tctcgccgaa gcggtcaaca tttcccacat agtccatact
    35521 gtcttcaatc gcaacacctt gcgctcccag ctcaatcaag agattggaaa ccaactcctc
    35581 tccctcacgc ttcactgtaa cttttaactc ttgccatgtt tccatcatta agataccaag
    35641 cccgtaaaac acaaaaccaa aataggaaat tctctgaaga cgcttgtgtc taagagaagt
    35701 ttatcttttt ggcacagtgt ttagggcggg ttcagtttag aaatttaact gaaccatcct
    35761 ttctaatcac ttacttttaa ataatctttt aatctctctt gcaactgagg cacaacttga
    35821 ctggaactaa gaaattcctc aacattcatc agctgatagc cctgtccttc atctccgaag
    35881 atgatattgt caaattgttc ttgtcttagc tgaccaacca taaagaccga tttcttgcct
    35941 ttaaaaatta cgctaggata aatcttgctc caaagcagac agtcttcatc taaatgaatt
    36001 cccagttcct cataaacttc acgccgagcg cattcaaaag ggctttcgtc cccttcacgg
    36061 ccaccacctg gcaactccca catgttggga caagggatat cgtccttgtc atcacgcaaa
    36121 atcgtcagta gcttatcccc acaaaagagg gcaatcttgc aaccttggaa atcagaaatt
    36181 tctagttcca tcttcagttc cttctaacat ttccttttcc agctctgcta acaagttttc
    36241 ataatagcgt ttctcgtccc tcaacattcg actactatcc attttctgtc tagcaatctt
    36301 gagagcctta cgagttcgat ctacatcttt cttcaccttt aattgatacc aggcttgtat
    36361 cacttgaaga ttggacagtt tgagagacag aaacgatttg acctgtcgaa tactagcata
    36421 ttgctccgct tgctcaaaat ctccttccaa caaggcgata tgaagcaggg atagttgggc
    36481 aactgtctgc atcatcggag tagttgtcct ctcaagtaat gcttgaaact gctgtttagc
    36541 tacttcttcc ttcccttcca aaatggaaac ttcaccttgc atacctaata caccatccgc
    36601 aaaactccct cgtgcatcct caggaactgc ttgaacaaag tctttcaaat catattcttg
    36661 aggagccagc aaagtttgag cagaatgtct caataccagg taggcgtatt tggtattttc
    36721 agggtgttgt agtaattccc aaatttttgc tccatcggtg atgtcgactg gcaaaatgtt
    36781 atttaggaag aaagataaat taagaaaaat ccaagtccct gcaaaatacc agcttcttgt
    36841 caaaaagcca aacactatcg ccaataatat caagccgaga tgaaccatca agcctcctga
    36901 aagcatcagg atgattcttt gatcgctttc atcctctttt aaaccaatgt attgagcacc
    36961 aacatttttc agaatggctg ttctactaag atgaaacctg cctgactttt tggtcaaaat
    37021 aaaatgtcct aatccaaaag ccaccagccg atagcctgtc aagtagccac aaaaagcatg
    37081 acccagctca tgaagaataa agattaaata catgcttaga agagcgaagg cataaccaaa
    37141 agtaaaggct aaaactgcgg aataccccaa ctctgcaaat gcgattgttc cacaagcaaa
    37201 agctagcata ataaagacaa cagctagcac ataaaccaaa taagtcccaa ttttcttcat
    37261 aacacctcca accaactcct agtatcttgg ataaggataa aatcctccct cttccaagcc
    37321 aacttttcct tcttcaaaga cttcttgatt ccattccata acaaattcct ctgcttctgg
    37381 atcttccaaa aagtccatga gggtatctag cccaacctcc gcagtatctt tgaggaaaag
    37441 ggcaaaataa gctaaaaact cgcgagaaaa tcctttttta ggtagataag ggataaccgt
    37501 taaatagtct tctgcattga cggttgactt ggcaggattg tagaaaagga ccgcttcctc
    37561 aaaaagaatg tcatctgatg aaacctctcc gtcttcatcc accatctcca cacctgcagc
    37621 attttgcgct tccaatagaa aactcacttc taccgcatgg ttgcgtttgt cccagctaat
    37681 ctcaaagtca aagggaaagt tcttgtccaa ctcttcctct aaaacatcta aaaatccgta
    37741 tgttgccatt ttgtcctctt tctatgcgac tctttaatcg ccccgattgc tcggaaatat
    37801 gctaaaatag atactaccat cttaccacaa aattatttta tgtcctaatt ataccatatt
    37861 acctcattta aacccttggt atcagtgatt ttcttaaaag tctgatttct tcatttctca
    37921 taaaaatcaa tataaaaagc cctcgaaagg gctaataaat ctataaaatc aataggcgag
    37981 taactagcac aagtggacgt gcttttttat tgactattac cacgatacca cgcttaatct
    38041 taggcttgaa ctttcttatc tgcaatagcg tctgtcaaag tctgagaaaa gttaagtccc
    38101 atttctcgtc ccaacttatc tgcccatttt ggtatggtca aagtcttttt aatgggttcc
    38161 tgacttccta ggtattctga tacatcaaca gataccatag aaataaaaga tttatcaagg
    38221 tcataggttg acacgaaatc ttcatcatct ttaaaaggat cattatcaat taaagacaag
    38281 ctattgatat ctgatggctg aggtaactct ccatcactct ctatcaaatc tgcaacagtt
    38341 atccctagcc actccgaccc catagccaaa gcctcagaaa tcccctctcc ttgtgtagct
    38401 gagtattcaa aatctgggaa atggacaaaa taagtcgctt ctgttccgtc tgtgtcgtca
    38461 taataaaata aagctggata cgtaactaac atttcactac ctccatatca aaaagcaggg
    38521 actgaatttt acaacccagc ttgctttctt atccctcttt cagtgtactt attcagctca
    38581 ccatgaggga ttgtgatagg tctttcccct tgcttctcga ttttaatatg ggaaccttta
    38641 ccgcctctag tctttatcaa ccatgggccg taaggagttt aaccatctct ttttgtgtca
    38701 taggcatagc gcttttacct cctgacaaca ccattataac acgtgttaca cgtattgtaa
    38761 aggagtgata cttattattc tattatacat aaaagcccct agatgtggtt ctaagggaag
    38821 ccaatttatt catacctatt tttctaatga gtagtaaaaa ctgcttcttt atcgagcaat
    38881 tcatcatctg tatagtcaat tgtaaaagta tctcgatcta agacagattg aggcggagtt
    38941 gaatgaatca taggaacact gcgtactcta tattttttat ctccaatttt tacaaactga
    39001 tactcttcga aaatcaaatt caaaccacgt caacgtcgcc tt
//
LOCUS       DAVBOD010000015        38411 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 640-05
            SAMEA1012484-rid20186543.denovo.015, whole genome shotgun sequence.
ACCESSION   DAVBOD010000015 DAVBOD010000000
VERSION     DAVBOD010000015.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012484
            Sequence Read Archive: ERR059358
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 38411)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 38411)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979948.1
            Genome Coverage       :: 595x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:03:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,266
            CDSs (total)                      :: 2,219
            Genes (coding)                    :: 2,091
            CDSs (with protein)               :: 2,091
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 71 of 128
            Pseudo Genes (incomplete)         :: 50 of 128
            Pseudo Genes (internal stop)      :: 33 of 128
            Pseudo Genes (multiple problems)  :: 22 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..38411
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012484-rid20186543.denovo.015"
                     /strain="NIG 640-05"
                     /db_xref="taxon:1313"
     gene            complement(56..1066)
                     /locus_tag="VQ862_000844"
     CDS             complement(56..1066)
                     /locus_tag="VQ862_000844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YeiH family putative sulfate export transporter"
                     /protein_id="HET3115214.1"
                     /translation="MSFLSKNGAGILVCLLISIVSWYLGGFFPVIGAPVFAIFMGMLL
                     HPFLSSYKQLDAGLTFSSKKLLQYAVILLGFGLNISQVFAVGQSSLPVILSTISIALI
                     VAYLFQRFFALDTKLATLIGVGSSICGGSAIAATAPVIHAKEKEVAQAISVIFFFNVL
                     AALIFPTLGTWLHLSNDGFALFAGTAVNDTSSVTATASAWDSLYQTNALESATIVKLT
                     RTLAIIPITIFLSYWQSREQKNKQGLQLKKVFPLFILYFILASLLTTLLTSLGVSSSF
                     FTPLKQLSKFLIIMAMSAIGLKTNLVAMVKSSGKSIVLGAVCWIAIILTSLGMQTLIG
                     IF"
     gene            1215..2384
                     /locus_tag="VQ862_000845"
     CDS             1215..2384
                     /locus_tag="VQ862_000845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HET3115215.1"
                     /translation="MDLTKRFNKQLDKIQVSLIRQFDQAISEIPGVLRLTLGEPDFTT
                     PDHVKEAAKRAIDQNQSYYTGMSGLLTLRQAASDFVKEKYQLDYAPENEILVTIGATE
                     ALSATLTAILEEGDKVLLPAPAYPGYEPIVNLVGAEIVEIDTTENGFVLTPEMLEKAI
                     LEQGDKLKVVILNYPANPTGITYSREQLETLAAVLRKYEIFVVCDEVYSELTYTGEAH
                     VSLGTMLRDQTIIINGLSKSHAMTGWRLGLIFAPATFTAQLIKSHQYLVTAANTMAQH
                     AAVEALTAGKNDAEPMKKEYIQRRDYIIEKMTALGFEIIKPDGAFYIFAKIPAGYNQD
                     SFAFLKDFAQKKAVAFIPGAAFGRYGEGYVRLSYAASMETIKEAMKRLEEYMREA"
     gene            2381..3151
                     /gene="recO"
                     /locus_tag="VQ862_000846"
     CDS             2381..3151
                     /gene="recO"
                     /locus_tag="VQ862_000846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000616164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecO"
                     /protein_id="HET3115216.1"
                     /translation="MIQSITSQGLVLYNRNFREDDKLVKIFTEQVGKRMFFVKHAGQS
                     KLAPVIQPLVLARFLLRINDDGLSYIEDYHEVMTFPKINSDLFVMAYATYVAALADAS
                     LQDNQQDAPLFAFLQKTLELMEAGLDYQVLTNIFEIQILTRFGISLNFNECVFCHRVG
                     QAFDFSFKYGACLCPEHYHEDKRRCHLNPNISYLLNQFQAIDFETLETISLKPGIKQE
                     LRQFMDQLYEEYVGIHLKSKKFIDSLADWGQLLKEEKK"
     gene            3148..4140
                     /gene="plsX"
                     /locus_tag="VQ862_000847"
     CDS             3148..4140
                     /gene="plsX"
                     /locus_tag="VQ862_000847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000717456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acyltransferase PlsX"
                     /protein_id="HET3115217.1"
                     /translation="MKKIAVDAMGGDYAPQAIVEGVNQALSDFSDIEVQLYGDEAKIK
                     QYLTATERVSIIHTDEKIDSDDEPTRAIRNKKNASMVLAAKAVKDGEADAVLSAGNTG
                     ALLAAGFFIVGRIKNIDRPGLMSTLPTVDGKGFDMLDLGANAENTAQHLHQYAVLGSF
                     YAKNVRGIAQPRVGLLNNGTESSKGDPLRKETYELLVADESLNFIGNVEARDLMNGVA
                     DVVVADGFTGNAVLKSIEGTAMGIMGLLKTAITGGGLRAKLGALLLKDSLRGLKKQLN
                     YSDIGGAVLFGVKAPVVKTHGSSDAKAVYSTIRQIRTMLETDVVAQTAREFSGE"
     gene            4146..4379
                     /locus_tag="VQ862_000848"
     CDS             4146..4379
                     /locus_tag="VQ862_000848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HET3115218.1"
                     /translation="MTEKEIFDRIVTIIQERQGEDFVVTESLSLKDDLDADSVDLMEF
                     ILTLEDEFSIEISDEEIDQLQNVGDVVKIIQGK"
     gene            4425..4715
                     /locus_tag="VQ862_000849"
                     /pseudo
     CDS             4425..4715
                     /locus_tag="VQ862_000849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5/IS1182 family transposase"
     gene            4918..5148
                     /gene="blpU"
                     /locus_tag="VQ862_000850"
     CDS             4918..5148
                     /gene="blpU"
                     /locus_tag="VQ862_000850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpU"
                     /protein_id="HET3115219.1"
                     /translation="MNTKKMSQFEIMDTEMLACVEGGGCNWGDFAKAGVGGGAVRGLQ
                     LGIKTRTWQGAATGAAGGAILGGVAYAATCWW"
     gene            5863..8016
                     /locus_tag="VQ862_000851"
     CDS             5863..8016
                     /locus_tag="VQ862_000851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000668284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide cleavage/export ABC transporter"
                     /protein_id="HET3115220.1"
                     /translation="MKFGKRHYRPQVDQMDCGVASLAMVFGYYGSYYFLAHLRELAKT
                     TMDGTTALGLVKVAEEIGFETRAIKADMTLFDLPDLTFPFVAHVLKEGKLLHYYVVTG
                     QDKDSIHIADPDPGVKLTKLPRERFEEEWTGVTLFMAPSPDYKPYKEQKNGLLSFIPI
                     LVKQRGLIANIVLATLLVTGINIVGSYYLQSIIDTYVPDQMRSTLGIISIGLVIVYIL
                     QQILSYAQEYLLLVLGQRLSIDVILSYIKHVFHLPMSFFATRRTGEIVSRFTDANSII
                     DALASTILSIFLDVSTVVIISLVLFSQNTNLFFMTLLALPIYTVIIFAFMKPFEKMNR
                     DTMEANAVLSSSIIEDINGIETIKSLTSESQRYQKIDKEFVDYLKKSFTYSRAESQQK
                     ALKKVAHLLLNVGILWMGAVLVMDGKMSLGQLITYNTLLVYFTNPLENIINLQTKLQT
                     AQVANNRLNEVYLVASEFEEKKTVEDLSLMKGEMTFKQVHYKYGYGRDVLSDINLTVP
                     QGSKVAFVGISGSGKTTLAKMMVNFYDPSQGEISLGGVNLNQIDKKALRQYINYLPQQ
                     PYVFNGTILENLLLGAKEGTTQEDILRAVELAEIREDIERMPLNYQTELTSDGAGISG
                     GQRQRIALARALLTDAPVLILDEATSSLDILTEKRIVDNLMALDKTLIFIAHRLTIAE
                     RTEKVVVLDQGKIVEEGKHADLLAQGGFYAHLVNS"
     gene            8029..9378
                     /locus_tag="VQ862_000852"
     CDS             8029..9378
                     /locus_tag="VQ862_000852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000801614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyD family secretion protein"
                     /protein_id="HET3115221.1"
                     /translation="MKPEFLESAEFYNRRYHNFSSSVIVPMALLLVFLLGFATVAEKE
                     MSLSTRATVEPSRILANIQSTSNNRILVNHLEENKLVKKGDLLVQYQEGAEGVQAESY
                     ASQLDMLKDQKKQLEYLQKSLQEGENHFPEEDKFGYQATFRDYISQAGSLRASTSQQN
                     ETIASQNAAASQTQAEIGNLISQTEAKIRDYQTAKSAIETGASLAGQNLAYSFYQSYK
                     SQGEENPQTKVQAVAQVEAQISQLESSLATYRVQYAGSGTQQAYASGLSSQLESLKSQ
                     HLAKVGQELTLLAQKILEAESGKKVQGNLLDKGKITASEDGVLHLNPETSDSSMVAEG
                     ALLAQLYPSLEREGKAKLTAYLSSKDVARIKVGDSVRYTTTHDAGNQLFLDSTITSID
                     ATATKTEKGNFFKIEAETNLTSEQAEKLRYGVEGRLQMITGKKSYLRYYLDQFLNKE"
     gene            9548..10255
                     /locus_tag="VQ862_000853"
     CDS             9548..10255
                     /locus_tag="VQ862_000853"
                     /EC_number="6.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000043309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HET3115222.1"
                     /translation="MSKQLIYSGKAKDIYTTEDENLIISTYKDQATAFNGVKKEQIAG
                     KGVLNNQISSFIFEKLNAAGVATHFVEKLSDTEQLNKKVKIIPLEVVLRNYTAGSFSK
                     RFGVDEGIALETPIVEFYYKNDDLDDPFINDEHVKFLQIADDQQIAYLKEETRRINEL
                     LKVWFAEIGLKLIDFKLEFGFDKDGKIILADEFSPDNCRLWDADGNHMDKDVFRRGLG
                     ELTDVYEIVWEKLQELK"
     gene            10457..14182
                     /locus_tag="VQ862_000854"
     CDS             10457..14182
                     /locus_tag="VQ862_000854"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000361233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase"
                     /protein_id="HET3115223.1"
                     /translation="MDKRIFVEKKADFQVKSESLVRELQHNLGLSSLKSIRIVQVYDV
                     FDLAEDLFAPAEKHIFSEQVTDHVLDEVSVQADLANYAFFAIESLPGQFDQRAASSQE
                     ALLLLGSSSDVTVNTAQLYLVNKDIDVTELEAVKNYLLNPVDSRFKDITTGIAKQEFS
                     ESDKTIPKLTFFESYTAEDFARYKAEQGMAMEVDDLLFIQDYFKSIGRVPTETELKVL
                     DTYWSDHCRHTTFETELKHIDFSASKFQKQLQSTYDKYIAMREELGRSEKPQTLMDMA
                     TIFGRYERANGRLDDMEVSDEINACSVEIEVDVDGVKEPWLLMFKNETHNHPTEIEPF
                     GGAATCIGGAIRDPLSGRSYVYQAMRISGAGDITAPISETRAGKLPQQVISKTAAHGY
                     SSYGNQIGLATTYVREYFHPGFVAKRMELGAVVGAAPKGNVVREKPEAGDVIILLGGK
                     TGRDGVGGATGSSKVQTVESVETAGAEVQKGNAIEERKIQRLFRNGNVTRLIKKSNDF
                     GAGGVCVAIGELADGLEIDLNKVPLKYQGLNGTEIAISESQERMAVVVRPEDVDAFVA
                     ECNKENIDAVVVATVTEKPNLVMNWNGETIVDLERRFLDTNGVRVVVDAKVVDKDVKL
                     PEERQTSAETLESDTLTVLSDLNHASQKGLQTVFDCSVGRSTVNHPLGGRYQLTPTEA
                     SVQKLPVQHGVTHTASVIAQGFNSYVAEWSPYHGAAYAVIEATARLVAAGANWSKARF
                     SYQEYFERMDKQAERFGQPVAALLGSIEAQIQLGLPSIGGKDSMSGTFEELTVPPTLV
                     AFGVTTADSRKVLSPEFKAVGENIYYIPGQALSAEIDFDLIKKNFAQFEASQADHKVT
                     SASAVKYGGVVESLALATFGNYIGAEVTLPELKTALTAQLGGFVFTSPEEIAGVEKIG
                     QTKADFTLTVNGVKLDGHKLDSAFQGTLEEVYPTEFTQAKELEEVPAVASDVVIKAKE
                     KVEKPVVYIPVFPGTNSEYDSAKAFEKEGAEVNLVPFVTLNEEAIVKSVETMVDNIDK
                     TNILFFAGGFSAADEPDGSAKFIVNILLNEKVRVAIDSFIARGGLIIGICNGFQALVK
                     SGLLPYGNFEDANSTSPTLFYNDANQHVAKMVETRIANTNSPWLAGVQVGDIHAIPVS
                     HGEGKFVVTAEEFAELRDNGQIFSQYVDFNGKPSMDSKYNPNGSVHAIEGITSKNGQI
                     IGKMGHSERYEDGLFQNIPGNKDQHLFASAVKHFTGK"
     gene            14275..15717
                     /locus_tag="VQ862_000855"
     CDS             14275..15717
                     /locus_tag="VQ862_000855"
                     /EC_number="2.4.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000220605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidophosphoribosyltransferase"
                     /protein_id="HET3115224.1"
                     /translation="MTYEVKSLNEECGVFGIWGHPDAAKLTYFGLHSLQHRGQEGAGI
                     LSNDQGQLKRHRDMGLLSEVFRNPSNLDKLTGAGAIGHVRYATAGEASVDNIQPFLFR
                     FHDMQFGLAHNGNLTNAASLKKELEQRGAIFSATSDSEILAHLIRRSHNPSLMGKIKE
                     ALSLVKGGFAYILLFEDKLIAALDPNGFRPLSIGKMANGAVVVSSETCAFEVIGAEWI
                     CDLKPGEIVIIDDEGIQYDSYTDDTQLAICSMEYIYFARPDSNIHGVNVHTARKRMGA
                     QLAREFKHEADIVVGVPNSSLSAAMGFAEESGLPNEMGLIKNQYTQRTFIQPTQELRE
                     QGVRMKLSAVSGVVKGKRVVMVDDSIVRGTTSRRIVQLLKEAGATEVHVAIGSPALAY
                     PCFYGIDIQTRQELIAANHTVEETRQIIGADSLTYLSIDGLIESIGIETDAPNGGLCV
                     AYFDGDYPTPLYDYEEDYRRSLEEKTSFYK"
     gene            15754..16776
                     /locus_tag="VQ862_000856"
     CDS             15754..16776
                     /locus_tag="VQ862_000856"
                     /EC_number="6.3.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine cyclo-ligase"
                     /protein_id="HET3115225.1"
                     /translation="MTNKNAYAQSGVDVEAGYEVVERIKKHVARTESAGVMGALGGFG
                     GMFDLSKTGVKEPVLISGTDGVGTKLMLAIKYDKHDTIGQDCVAMCVNDIIAAGAEPL
                     YFLDYVATGKNEPAKLEQVVAGVAEGCVQAGAALIGGETAEMPGMYGEDDYDLAGFAV
                     GVAEKSQIIDGSKVVEGDVLLGLASSGIHSNGYSLVRRVFADYTGEEVLPELEGKKLK
                     EVLLEPTRIYVKAVLPLIKEELVNGIAHITGGGFIENVPRMFADDLAAEIDESKVPVL
                     PIFKALEKYGQIKHEEMFEIFNMGVGLMLAVSPENVERVKELLDEAVYEIGRIVKKEN
                     ESVIIK"
     gene            16773..17318
                     /gene="purN"
                     /locus_tag="VQ862_000857"
     CDS             16773..17318
                     /gene="purN"
                     /locus_tag="VQ862_000857"
                     /EC_number="2.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylglycinamide formyltransferase"
                     /protein_id="HET3115226.1"
                     /translation="MKKIAVFASGNGSNFQVIAEEFPVEFVFSDHRDAYVLERAKQLG
                     VLSYAFELKEFESKADYEAALVELLEEHQIDLVCLAGYIKIVGPTLLSAYEGRIVNIH
                     PAYLPEFPGAHGIEDAWNAGVGQSGVTIHWVDSGVDTGQVIKQVRVPRLADDTIDRFE
                     ARIHEAEYRLYLEVVKALFTD"
     gene            17402..17911
                     /locus_tag="VQ862_000858"
     CDS             17402..17911
                     /locus_tag="VQ862_000858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000894002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HET3115227.1"
                     /translation="MLESKKTTRYVFYVYLMLLTWGILFKFETNPEFIAFFLAPRYIN
                     WIPFSEPLIVDGKIVFAEMLFNLISFIPLGVCFPLIKTNLSSLRIVGTGFLISLLFEC
                     LQYILAIGITDITDLTLNTLGVCVGLLIYQIFIRVFKSQTRKWINILGMLSLGFAYLV
                     LLLLHLIGV"
     gene            17936..19483
                     /gene="purH"
                     /locus_tag="VQ862_000859"
     CDS             17936..19483
                     /gene="purH"
                     /locus_tag="VQ862_000859"
                     /EC_number="2.1.2.3"
                     /EC_number="3.5.4.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006146083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     phosphoribosylaminoimidazolecarboxamide
                     formyltransferase/IMP cyclohydrolase"
                     /protein_id="HET3115228.1"
                     /translation="MTKRVLISVSDKAGIVEFAQELKKLGWEIISTGGTKVALDNAGV
                     DTIAIDDVTGFPEMMDGRVKTLHPNIHGGLLARRDLDSHLEAAKDNKIELIDLVVVNL
                     YPFKETILKPDVTYADAVENIDIGGPSMLRSAAKNHASVTVVVDPADYAVVLDELAAN
                     GETSYETRQRLAAKVFRHTAAYDALIAKYFTAQVGESKPEKLTLTYDLKQPMRYGENP
                     QQDADFYQKALPTDYSIASAKQLNGKELSFNNIRDADAAIRIIRDFKDSPTVVALKHM
                     NPCGIGQADDIETAWEYAYESDPVSIFGGIVVLNREVDAATAEKMHGVFLEIIIAPSY
                     TDEALAILINKKKNLRILALPFNAQEASEVEAEYTGVVGGLLVQNQDVVKESPADWQV
                     VTKRQPTETEATALEFAWKAIKYVKSNGIIVTNDHMTLGVGPGQTNRVASVRLAIDQA
                     KDRLDGAVLASDAFFPFADNVEEIAKAGIKAIIQPGGSVRDQESIEAADKYGLTMVFT
                     GVRHFRH"
     gene            19605..20867
                     /gene="purD"
                     /locus_tag="VQ862_000860"
     CDS             19605..20867
                     /gene="purD"
                     /locus_tag="VQ862_000860"
                     /EC_number="6.3.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000772208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylamine--glycine ligase"
                     /protein_id="HET3115229.1"
                     /translation="MKLLVVGSGGREHAIAKKLLESKDVEKVFVAPGNDGMTLDGLEL
                     VNISISEHSKLIDFAKTNDVAWTFIGPDDALAAGIVDDFNQAGLKAFGPTRAAAELEW
                     SKDFAKEIMVKYGVSTAAYGTFSDFEEAKAYIEKHGAPIVVKADGLALGKGVVVAETV
                     EQAVEAAHEMLLDNKFGDSGARVVIEEFLEGEEFSLFAFVNGDKFYIMPTAQDHKRAY
                     DGDKGPNTGGMGAYAPVPHLPQSVVDTAVDTIVKPVLEGMIKEGRPYLGVLYAGLILT
                     ADGPKVIEFNARFGDPETQIILPRLTSDFAQNITDILDSKEPNITWTDKGVTLGVVVA
                     SKGYPLDYSKGVELPVKTDGDIITYYAGAKFAENSRALLSNGGRVYMLVTTADTVKEA
                     QASIYQELSQQKIEGLFYRTDIGSKAIK"
     gene            21124..21240
                     /locus_tag="VQ862_000861"
     CDS             21124..21240
                     /locus_tag="VQ862_000861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazole carboxylase"
                     /protein_id="HET3115230.1"
                     /translation="MKERLDDNPIVQGNWKTLGFQFRHETPLVAAAVPHKLR"
     gene            21270..21758
                     /gene="purE"
                     /locus_tag="VQ862_000862"
     CDS             21270..21758
                     /gene="purE"
                     /locus_tag="VQ862_000862"
                     /EC_number="4.1.1.21"
                     /EC_number="5.4.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009567721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide mutase"
                     /protein_id="HET3115231.1"
                     /translation="MKPVISIIMGSKSDWATMQKTAEVLDRFGVAYEKKVVSAHRTPD
                     LMFKHAEEARSRGIKIIIAGAGGAAHLPGMVAAKTILPVIGVPVNSRALSGVDSLYSI
                     VQMPGGVPVATMAIGEAGATNAALFALRLLSVEDQSIATALADFAEEQGKIAEESSNE
                     LI"
     gene            21745..22836
                     /gene="purK"
                     /locus_tag="VQ862_000863"
     CDS             21745..22836
                     /gene="purK"
                     /locus_tag="VQ862_000863"
                     /EC_number="6.3.4.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000099033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide
                     synthase"
                     /protein_id="HET3115232.1"
                     /translation="MSSSKTIGIIGGGQLGQMMAISAIYMGHKVIALDPAADCPASRV
                     AEIIVAPYNDVDALRQLADRCDVLTYEFENVDADGLDVVIKDGQLPQGTDLLRISQNR
                     IFEKDFLSNKAQVTVAPYKVVTSSLDLADIDLSKNYVLKIATGGYDGHGQNVIRSADD
                     LEEAYALADSAACVLEEFVNFDLEISVIVSGNGKEVTFFPVQENIHRNNILSKTIVPA
                     RISESLADKAKAMAVRIAEQLNLSGTLCVEMFATADDIIVNEIAPRPHNSGHYSIEAC
                     DFSQFDTHILGVLGAPLPAIKLHAPAVMLNVLGQHVEAAEKYVTENPSTHLHMYGKIE
                     AKHNRKMGHVTLFSDVPDSVEEFGEGIDF"
     gene            22846..23073
                     /locus_tag="VQ862_000864"
     CDS             22846..23073
                     /locus_tag="VQ862_000864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazole carboxylase"
                     /protein_id="HET3115233.1"
                     /translation="MIQIIVNAFIEKDKTGAVVEVLYASADQDKVQAKYEELAAQYPE
                     NYLAIYDVPLDTDLNTLDHYPSVFIGKEEFE"
     gene            23136..24434
                     /gene="purB"
                     /locus_tag="VQ862_000865"
     CDS             23136..24434
                     /gene="purB"
                     /locus_tag="VQ862_000865"
                     /EC_number="4.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000572899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate lyase"
                     /protein_id="HET3115234.1"
                     /translation="MINRYSRPEMANIWSEENKYRAWLEVEILSDEAWAELGEIPKED
                     VALIRKKADFDIDRILEIEQETRHDVVAFTRAVSETLGEERKWVHYGLTSTDVVDTAY
                     GYLYKQANDIIRRDLENFTNIIADKAKEHKFTIMMGRTHGVHAEPTTFGLKLATWYSE
                     MKRNIERFEHAAAGVEAGKISGAVGNFANIPPFVEEYVCDKLGIRAQEISTQVLPRDL
                     HAEYFAVLASIATSIERMATEIRGLQKSEQREVEEFFAKGQKGSSAMPHKRNPIGSEN
                     MTGLARVIRGHMITAYENVALWHERDISHSSAERIITPDTTILIDYMLNRFGNIVKNL
                     TVFPENMIRNMNSTFGLIFSQRAMLTLIEKGMTREQAYDLVQPKTAYSWDNQVDFKPL
                     LEADSEVTSRLTQEEIDEIFNPVYYTKRVDDIFERLGLGD"
     gene            complement(24489..28424)
                     /gene="strH"
                     /locus_tag="VQ862_000866"
     CDS             complement(24489..28424)
                     /gene="strH"
                     /locus_tag="VQ862_000866"
                     /EC_number="3.2.1.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000679939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-N-acetylhexosaminidase"
                     /protein_id="HET3115235.1"
                     /translation="MKHEKQQRFSIRKYAVGAASVLIGFAFQAQTVAADGVTTTTENQ
                     PTIHTVSDSPQSSENRTEETPKAELQPEAPKTVETETPATDKVASLPKTEEKPQEEVS
                     STPSDKAEVVTQTSAEKETANKKAEEASPKKEEAKEVDSKESNTDKTDKDKPAKKDEA
                     KAEADKPETEAGKERAATVNEKLAKKKIVSIDAGRKYFSPEQLKEIIDKAKHYGYTDL
                     HLLVGNDGLRFMLDDMSITANGKTYASDDVKRAIEKGTNDYYNDPNGNHLTESQMTDL
                     INYAKDKGIGLIPTVNSPGHMDAILNAMKELGIQNPNFSYFGKKSARTVDLDNEQAVA
                     FTKALIDKYAAYFAKKTEIFNIGLDEYANDATDAKGWSVLQADKYYPNEGYPVKGYEK
                     FIAYANDLARIVKSHGLKPMAFNDGIYYNSDTSFGSFDKDIIVSMWTGGWGGYDVASS
                     KLLAEKGHQILNTNDAWYYVLGRNADGQGWYNLDQGLNGIKNTPITSVPKTEGADIPI
                     IGGMVAAWADTPSARYSPSRLFKLMRHFANANAEYFAADYESAEQALNEVPKDLNRYT
                     AESVTAVKEAEKAIRSLDSNLSRAQQDTIDQAIAKLQETVNNLTLTPEALKEEEAKRE
                     VEKLAKNKVISIDAGRKYFTLNQLKRIVDKASELGYSDVHLLLGNDGLRFLLDDMTIT
                     ANGKTYASDDVKKAIIEGTKAYYDDPNGTALTQAEVTELIEYAKSKDIGLIPAINSPG
                     HMDAMLVAMEKLGIKNPQAHFDKVSKTTMDLKNEEAMNFVKALIGKYMDFFAGKTKIF
                     NFGTDEYANDATSAQGWYYLKWYQLYGKFAEYANTLAAMAKERGLQPMAFNDGFYYED
                     KDDVQFDKDVLISYWSKGWWGYNLASPQYLASKGYKFLNTNGDWYYILGQKPEDGGGF
                     LKKAIENTGKTPFNQLASTKYPEVDLPTVGSMLSIWADRPSAEYKEEEIFELMTAFAD
                     HNKDYFRANYNALREELAKIPTNLEGYSKESLEALDAAKTALNYNLNRNKQAELDTLV
                     ANLKAALQGLKPAATHSGSLDENEVAANVETRPELITRTEEIPFEVIKKENPNLPAGQ
                     ENIITAGVKGERTHYISVLTENGKTTETVLDSQVTKEVINQVVEVGAPVTHKGDESGL
                     APTTEVKPRLDIQKEEIPFTTVTRENPLLLKGKTQVITKGVNGHRSNFYSVSTSADGK
                     EVKTLVNSVVAQEAVTQIVEVGTMVTHVGDENGQAAIAEEKPKLEIPSQPAPSTAPAE
                     ESKALPQDPAPVVTEKKLPETGTHDSAGLVVAGLMSTLAAYGLTKRKED"
     gene            complement(28740..29456)
                     /locus_tag="VQ862_000867"
     CDS             complement(28740..29456)
                     /locus_tag="VQ862_000867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001007200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HET3115236.1"
                     /translation="MAIPKYQYIKDELKNKIISGQFSSGDKFYTEAELISMYDVSSIT
                     VVRALNDLAKDGYIVRQQGKGTFVSRARKHKLVEFSDIELFNAKDDKVTVLSIERGNK
                     LVYLEKLGLRGDQFYYKIERIRESNSVVYIYHTSYIPEQYINANYPNLEYYSSIYNRF
                     KLDYHIHMNDEHFEEINEIVFPTPEHAASVLGVDEQFPTVLQTKITKLESTGQVLEYS
                     ETYKRSDYYKIKFISCDRDH"
     gene            29804..31591
                     /locus_tag="VQ862_000868"
     CDS             29804..31591
                     /locus_tag="VQ862_000868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-galactosidase"
                     /protein_id="HET3115237.1"
                     /translation="MTRFEIRDDFYLDGKSFKILSGAIHYFRVPPEDWYHSLYNLKAL
                     GFNTVETYVAWNLHEPREGEFHFEGDLDLEKFLQIAQDLGLYAIVRPSPFICAEWEFG
                     GLPAWLLTKNMRIRSSDPAYIEAVGRYYDQLLPRLVPRLLDNGGNILMMQVENEYGSY
                     GEDKAYLRAIRQLMEECGVTCPLFTSDGPWRATLKAGTLIEEDLFVTGNFGSKAPYNF
                     SQMQEFFDEHGKKWPLMCMEFWDGWFNRWKEPIITRDPKELADAVREVLEQGSINLYM
                     FHGGTNFGFMNGCSARGTLDLPQVTSYDYDALLDEEGNPTAKYLAVKKMMATHFSEYP
                     QLEPLYKESMELDAIPLVEKVSLFETLDSLSSPVESLYPQKMEELGQSYGYLLYRTET
                     NWDAEEERLRIIDGRDRAQLYVDGQWVKTQYQTEIGEDIFYQGKKKGLSRLDILIENM
                     GRVNYGHKFLADTQRKGIRTGVCKDLHFLLNWKHYPLPLDNPEKIDFSKGWTQGQPAF
                     YAYDFTVEEPKDTYLDLSEFGKGVAFVNGQNLGRFWNVGPTLSLYIPHSYLKEGANRI
                     IIFETEGQYKEEIHLTRKPTLKHIKGENL"
     gene            31588..32064
                     /locus_tag="VQ862_000869"
     CDS             31588..32064
                     /locus_tag="VQ862_000869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system
                     mannose/fructose/N-acetylgalactosamine-transporter subunit
                     IIB"
                     /protein_id="HET3115238.1"
                     /translation="MTIVGCRIDGRLIHGQVANLWAGKLNVSRIMVVDDEVVNNDIEK
                     SGLKLATPPGVKLSILPVEKAAANILAGKYDSQRLFIVARKPDRFLGLVEAGVPLETL
                     NVGNMSQTPETRSITRSINVVDKDVEDFHKLAEKGVKLTAQMVPNDPISDFLSLLK"
     gene            32092..32997
                     /locus_tag="VQ862_000870"
     CDS             32092..32997
                     /locus_tag="VQ862_000870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006149155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HET3115239.1"
                     /translation="MIQWWQILLLTLYSAYQICDELTIVSSAGSPVFAGFITGLIMGD
                     VTTGLLIGGNLQLFVLGVGTFGGASRIDATSGAVLATAFSVSQGIDAPLAITTIAVPV
                     AALLTYFDVLGRMTTTFFAHRVDAAIERFDYKGIERNYLLGAIPWALSRALPVFFALA
                     FGGAFVQSVVDFVEAYKWVADGLTLAGRMLPGLGFAILLRYLPVKRNLHYLAMGFGLT
                     AMLTVLYSYVTGLGGAVAGIVGTLPAEVAEKIGFVNNFKGLSMIGISIVGIFLAVLHF
                     KNSQKVAVAAPSTPSESGEIEDDEF"
     gene            32984..33799
                     /locus_tag="VQ862_000871"
     CDS             32984..33799
                     /locus_tag="VQ862_000871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000185291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HET3115240.1"
                     /translation="MTNSNYKLTKEDFNQINKRSLFTFQLGWNYERMQASGYLYMILP
                     QLRKMYGDGTPELKEMMKVHTQFFNTSPFFHTIIAGFDLAMEEKDGVGSKDAVNGIKT
                     GLMGPFAPLGDTIFGSLVPAIMGSVAATMAIAGQPWGIFLWIAVAVAYDIFRWKQLEF
                     AYKEGVNLINNMQSTLTALIDAASVLGVFMMGALVATVINFEISYKLPIGEKMIDFQD
                     ILNQIFPRLLPAIFTAFIFWLLGKKGMNSTKAIGIIIVLALALSALGHFALGM"
     gene            33806..34210
                     /locus_tag="VQ862_000872"
     CDS             33806..34210
                     /locus_tag="VQ862_000872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007284837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HET3115241.1"
                     /translation="MTKSLILVSHGRFCEELRGSTEMIMGPQDNIYTVALLPEDGPEE
                     FTAKFEAVIEGLDDFLVFADLLGGTPCNVVSRLIMEGRDIDLYAGMNLPMVIEFINAS
                     LTGADADYKSRAAESIVKVNDLLAGFDDDEDE"
     gene            34509..35675
                     /locus_tag="VQ862_000873"
     CDS             34509..35675
                     /locus_tag="VQ862_000873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HET3115242.1"
                     /translation="MLHYTKEDLLELGAEITTREIYQQPDVWREAFEFYQAKREEIAA
                     FLQEIADKHDYIKVILTGAGTSAYVGDTLLPYFKEVYDERKWNFNAIATTDIVANPAT
                     YLKKDVATVLVSFARSGNSPESVATVDLAKSLVDELYQVTITCAADGKLALQAHGDDR
                     NLLLLQPAVSNDAGFAMTSSFTSMMLTALLVFDPTEFAVKSERFEVVSSLARKVLDKA
                     EDVKELVDLDFNRVIYLGAGPFFGLAHEAQLKILELTAGQVATMYESPVGFRHGPKSL
                     INDNTVVLVFGTTTDYTRKYDLDLVREVAGDQIARRVVLLSDQAFGLENVKEVALGCG
                     GVLNDIYRVFPYIVYAQLFALLTSLKVENKPDTPSPTGTVNRVVQGVIIHEYQK"
     gene            35791..36828
                     /locus_tag="VQ862_000874"
     CDS             35791..36828
                     /locus_tag="VQ862_000874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose mutarotase"
                     /protein_id="HET3115243.1"
                     /translation="MKAYTERVFGNVEGEDVLAYRFETDGGYQLEVMTYGATILRYVA
                     PDKAGNFANVILGFDDFDSYVGNSPKHGASVGPVAGRIAGATFELNGKTYDLEVNNAS
                     NCNHSGSTGWDSSLFEVEEVSDHGLTLYTERTDGTGGFPGNLKIWISYHLEETGAYEI
                     SYKVTTDQDTLVNPTNHSYFNLSGDFTQTIDRHVFQLNTEGIYSIAPDGVPAKTPEAN
                     RDVVKHVYNGTLLKDIFAEEDEQIQLASGLDHPFALPAGHDNAGFLYDQNSGRFLLFK
                     TEAPCFVVYTANFVDESVIIGGQPMLQHNGIALEAQALPDAIHSDLKGQVILKAGQTF
                     TSKTRYELVVK"
     gene            37035..37889
                     /locus_tag="VQ862_000875"
     CDS             37035..37889
                     /locus_tag="VQ862_000875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000220702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HET3115244.1"
                     /translation="MTYEYKSHIYLAETVLNVKDLASQTAFYQQVIGLEILSQTETES
                     ILGLGGKVLVQLIQAQESGEVREHYGLYHLAILLPTRKALADVLKHLTDLQIPLVGGA
                     DHGYSEAIYLEDLEGNGIELYRDKPVSTWDIREDGRIIGVTEALAAQDIYELGERVEP
                     FILAEGTRMGHIHLSVKDSRKSSQFYQKVLGLEDKFSVPSASWIAAGDYHHHLAVNEW
                     GGKGLASRKQGLPGLAYYVIEVAHKKELLTIAQRAQEVDAPIKWMTSSQLEITDSDGI
                     VTCIRLAR"
     gene            38039..38279
                     /locus_tag="VQ862_000876"
                     /pseudo
     CDS             38039..38279
                     /locus_tag="VQ862_000876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001845567.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sensing transcriptional repressor"
BASE COUNT        10750 a         7404 c         9116 g        11141 t
ORIGIN      
        1 aacatatata cggcaaggcg acgttgacgt ggtttgaaga gattttcgaa gagtattaga
       61 aaatgccgat aagggtctgc ataccaaggc tggtgaggat gatggcaatc cagcagacgg
      121 ctccgagaac aatggatttt ccactggatt tgaccatagc gaccagatta gttttgagac
      181 cgatggcact catggccatg ataatgagga atttagagag ttgtttgaga ggggtaaaga
      241 aactactaga cacaccgaga gaggtcagaa gggtggttag gagcgatgca aggatgaagt
      301 aaaggataaa aagtgggaag acttttttca gttgtaagcc ttgcttattt ttttgctcgc
      361 gactttgcca gtaggagaga aagatagtga tggggatgat agctagggtg cgcgtgagtt
      421 tgacaatggt tgcggattcg agggcattgg tctggtagag actgtcccaa gcgctagctg
      481 tggcggttac agaggaagta tcattgaccg cagttcctgc aaagagggcg aagccgtcat
      541 tggatagatg aagccaggtg ccgagggttg gaaagatgag cgcagccaag acattgaaga
      601 aaaagataac ggagatggct tgggctactt ccttttcctt agcatggata acaggcgctg
      661 tcgctgcaat ggcagaaccc ccacagatag aagaacctac tccaatcaag gtagccagtt
      721 ttgtatccag ggcaaagaag cgctggaaga ggtaggcaac aatcaaggct attgaaatgg
      781 tggaaaggat gacagggagt gaagattgcc caactgcgaa gacttgagag atattgagac
      841 caaaaccaag caagataacg gcatactgga gcaatttctt ggaactaaag gtcaatccag
      901 catccagttg tttataagac gagagaaagg gatgtaggag catgcccata aaaatcgcaa
      961 aaacgggtgc gccaatcaca gggaagaatc ctcctaagta ccaagatacg atagaaatga
     1021 gaaggcagac caagatgcct gctccatttt ttgatagaaa tgacataaaa acctccaaat
     1081 agaatctgtt accattatag acctgtaaag aggaaaagta aaatagaaag tggaaagcta
     1141 ttctctaatg tatttttgcg gtcgggaggc ttttgtagta taatagagat acgttttgaa
     1201 agtaggaggt atctatggac ttaactaagc gctttaataa acagttagat aaaattcaag
     1261 tttcgttgat tcgtcagttt gaccaggcta tttcggagat tcctggggtc ttgcgtttga
     1321 ccttggggga acctgatttt acaacgccag accatgtcaa ggaggcggcc aagcgagcga
     1381 ttgatcagaa ccaatcctac tatacaggga tgagtggtct gctgactcta cgtcaggcag
     1441 ctagtgactt tgttaaggaa aagtaccaac tggactatgc tcctgaaaat gaaatcttgg
     1501 ttacaattgg ggcgacagag gctttatctg cgactttgac ggctattttg gaagagggag
     1561 acaaggtact tttgccagct cctgcttatc caggctatga accgattgtt aacttagttg
     1621 gggcagaaat tgttgagatt gatacgactg aaaatggttt tgtcttgact cctgagatgt
     1681 tggagaaggc cattttggag cagggtgata agctcaaggt ggttattctc aactatccag
     1741 ccaatccgac aggaattacc tacagtcgag agcagttaga gaccttggca gctgttttac
     1801 gcaagtatga aatttttgtt gtctgtgatg aggtttactc agaattgacc tacacaggcg
     1861 aagcccatgt gtctctagga acgatgttga gagaccagac tattattatc aatggtttgt
     1921 ctaaatcgca tgccatgaca ggttggcgtt tggggctgat tttcgctcct gcgaccttca
     1981 cagcccagtt aatcaagagt caccagtact tggtcactgc cgcaaatacc atggcgcaac
     2041 atgctgcggt agaagccttg acggctggta aaaacgatgc ggagcccatg aagaaggaat
     2101 atatccaacg tcgggactat atcatcgaaa aaatgactgc tcttggtttt gagattatca
     2161 aaccagacgg tgccttctat atttttgcta aaattccagc gggctacaat caagactcct
     2221 ttgcttttct gaaggatttt gctcagaaga aggccgttgc ctttatccct ggtgcagcct
     2281 ttggacgtta cggggaaggc tacgtccgcc tatcttatgc agccagcatg gagactatca
     2341 aagaagccat gaaacgactt gaggagtaca tgagagaagc atgattcagt ctatcacgag
     2401 tcaaggcttg gtgctttaca atcgcaattt tcgtgaggat gacaagctcg tcaaaatttt
     2461 tacagagcag gttggcaaac gcatgttttt tgtcaaacac gctggtcagt ctaagctggc
     2521 gcctgttatt cagcccttgg tgctggcacg atttctcttg cgaatcaatg atgacggact
     2581 cagttacatc gaagactatc atgaggtcat gacttttccc aagattaata gtgacctctt
     2641 tgtcatggcc tatgcgacct atgtggcagc tcttgcagat gctagtttgc aggacaatca
     2701 gcaggatgct cccttgtttg cttttttgca aaagactttg gagttgatgg aagcaggctt
     2761 ggattatcag gttttgacca atatttttga aattcaaatt ttgactcgat ttggaatcag
     2821 cctcaatttt aatgagtgtg tcttctgcca tcgggttggt caggcttttg acttttcttt
     2881 caaatatgga gcctgcctct gtccagagca ttatcatgag gataagagac gttgtcatct
     2941 caatcccaat atctcctatc tgctcaatca atttcaagct attgattttg agactttgga
     3001 gaccatttcg ctcaagcctg gaatcaagca agagctacgc caatttatgg atcaattata
     3061 tgaagagtac gttgggattc acctaaaatc aaagaaattt attgattccc tagcagactg
     3121 gggacaatta ctaaaagagg aaaagaaatg aaaaaaatcg cagtagatgc catggggggc
     3181 gattacgcac ctcaggccat tgttgagggt gtcaatcaag ccctatctga cttttcagat
     3241 atcgaggttc aactttacgg agatgaagct aaaatcaagc aatatctgac agcgacagag
     3301 cgcgtcagca ttatccatac ggatgagaag attgattcgg atgatgaacc tacgagagct
     3361 attaggaata agaaaaatgc cagtatggta ttggcagcca aggctgtcaa agatggtgaa
     3421 gcagacgctg tcctttcggc tgggaataca ggtgccttgt tggctgctgg attcttcatc
     3481 gtgggtcgta tcaagaatat cgaccgtcct gggcttatgt cgactttgcc gactgtagat
     3541 gggaagggat ttgacatgct agacctcggt gccaatgcgg aaaatacagc ccagcacctc
     3601 catcaatacg cggttctagg atccttctat gctaaaaatg ttcgtggcat tgcgcaacca
     3661 cgtgttggct tgctcaataa cggaacagag agtagcaagg gcgatccgct tcgtaaggaa
     3721 acttatgaat tactagtggc tgatgaaagt ttgaacttta tcggaaatgt ggaagcgcgt
     3781 gatttgatga atggcgttgc agatgttgtt gtggcagatg gtttcacggg aaacgctgtg
     3841 ctcaaatcca tcgaagggac agctatggga atcatgggct tgctcaagac agctattaca
     3901 ggtggtggtc ttcgagcgaa actaggtgcc ctccttctca aggacagcct cagaggtttg
     3961 aaaaaacaac tcaattattc agatattggt ggagcggtct tgtttggtgt taaggcacct
     4021 gttgtcaaga ctcatggctc aagcgatgcc aaggctgttt atagtacgat tcgtcagatc
     4081 cgtaccatgc tagaaacaga cgtggttgcc cagactgcgc gtgaattttc aggagaataa
     4141 aagagatgac agaaaaagaa atttttgacc gtattgtgac cattatccaa gagcgacagg
     4201 gagaggactt tgtcgtgaca gaatccttga gtctgaaaga cgatttggat gcggattctg
     4261 ttgacttgat ggagtttatc ttgactctgg aagatgaatt tagtatcgaa atcagcgatg
     4321 aagaaattga ccaactccaa aacgtaggag atgtggttaa aatcattcaa ggaaaatagc
     4381 aatcggagtt ccaagtcaac ggaagtagat ggtttttaga aatgagaaat atcggacaag
     4441 ctggtaaaat cttggctgac agtggttatc aagggctcat gaagatatat cctcaagcac
     4501 aaactccacg taaatccagc aaactcaagc cgctaacagt tgaagataaa gcctgtaatc
     4561 atgcgctatc taaggagaga agcaaggttg agaatatctt tgccaaagta aaaacgttta
     4621 aaatgttttc aacaacctat cgaaatcatc gtaaacgctt cggattacga atgaatttga
     4681 ttgctggtat tatcaatcat gaactaggat tctagttttg caggaagtct aatagtaaaa
     4741 aagtgattag aaaacatctt ttttaaaaat agagatgatt ttgaaacaaa aaagctaatt
     4801 caagacgttt ctatgccaat tcaagatttg gatgaaaaaa attaatagat actgttatac
     4861 taaacttgtc aagtttgtaa caagacaaat attaaaaata aaaaagaggt attcgttatg
     4921 aatacaaaaa agatgtcaca atttgaaatt atggatactg agatgcttgc ttgcgttgaa
     4981 ggtggcggat gcaattgggg agattttgcc aaagcaggtg ttggaggagg agcagtacga
     5041 ggtcttcagc taggaattaa aacaagaaca tggcaaggtg cagcaactgg tgctgcggga
     5101 ggagctatac ttggaggtgt ggcctatgca gcgacatgtt ggtggtaatt atggatttta
     5161 aaagttttat tattggttta gtagttggta tatttggtcc ttatatggat gatttaatta
     5221 gaaaaaaatt tttaaagtct tcggagaaga aaacagaaaa atctgttaaa aaataatcaa
     5281 aactataaat gatgaatctg aatcaaaatt attttgcgca tgtaaatagg agtcttatag
     5341 taacgagtca aaaaaggagt aactatgaat cgtaatttag aacggtgtta tctattctga
     5401 ctaggaatag atcataccag aggtagctta gaaatagcag agacattaga aattgaagta
     5461 ataaatagga tgtcgtaagt gttactatca atgatttatt tgtttcaagc ttgtctaggg
     5521 tgacagtaaa aaatcaattt cctttcaata gcatattttt agtgggcagt actcttgttc
     5581 tgcctatttt tttatccaaa aagtgcagtt gggagggaga taggctcatt tgggaaggaa
     5641 gtccagtttt tgtttagtga ttggggtaag atagttgtta tcagatgagt ttatactctt
     5701 cgaaaatcaa attcaaacca cgtcaacgtc gccttgccgt atatatgtga ctgacttcgt
     5761 cagtcctatc tacaacctca aaacagtgtt ttgagcagcc tgcggctagt ttcctagttt
     5821 gctctttgat tttcattgag tattagggaa aaggagatga atatgaaatt tgggaaacgt
     5881 cactatcgtc cgcaagtgga tcagatggac tgcggtgtag cttcattagc catggttttt
     5941 ggctactatg gtagttatta ttttttggct cacttgcgag aattggctaa gacgaccatg
     6001 gatgggacga cggctttggg cttggtcaag gtggcagagg agattggttt tgagacgcga
     6061 gccattaagg cggatatgac gctttttgac ttgccggatt tgacttttcc ttttgttgcc
     6121 catgtgctta aggaagggaa attgctccac tactatgtgg tgactgggca ggataaggat
     6181 agcattcata ttgccgatcc agatcccggg gtgaagttga ctaaactgcc acgtgagcgt
     6241 tttgaggaag aatggacagg agtgactctt tttatggcac ctagtccaga ctataagcct
     6301 tataaggaac aaaaaaatgg tctgctctct tttatcccta tattagtgaa gcagcgtggc
     6361 ttgattgcca atatcgtttt ggcaacactc ttggtaaccg ggattaacat tgtgggttct
     6421 tattatctgc agtctatcat tgatacctat gtgccagatc agatgcgttc gacactaggg
     6481 attatttcta ttgggctagt catcgtctac atcctccagc aaatcttgtc ttacgctcag
     6541 gagtatctct tgcttgtttt ggggcaacgc ttgtcgattg acgtgatttt gtcctatatc
     6601 aagcatgttt ttcacctccc tatgtccttc tttgcgacac gcaggacagg ggagatcgtg
     6661 tctcgtttta cagatgctaa cagtatcatc gatgcgctgg cttcgaccat cctttcgatt
     6721 ttcctagatg tgtcaacggt tgtcattatt tcccttgttc tattttcaca aaataccaat
     6781 ctctttttca tgactttatt ggcgcttcct atctacacag tgattatctt tgcctttatg
     6841 aagccgtttg aaaagatgaa tcgggatacc atggaagcca atgcggttct gtcttcttct
     6901 atcattgagg acatcaacgg tattgagact atcaagtcct tgaccagtga aagtcagcgt
     6961 taccaaaaaa ttgacaagga atttgtggat tatctgaaga aatcctttac ctatagtcga
     7021 gcagagagtc agcaaaaggc tctgaaaaag gttgcccatc tcttgcttaa tgtcggcatt
     7081 ctctggatgg gggctgttct ggtcatggat ggcaagatga gtttggggca gttgattacc
     7141 tataatacct tgctggttta ctttaccaat cctttggaaa atatcatcaa tctgcaaacc
     7201 aagcttcaga cagcgcaggt tgccaataac cgtctaaatg aagtgtatct agtagcttct
     7261 gagtttgagg agaagaaaac agttgaggat ttgagcttga tgaagggaga gatgaccttc
     7321 aagcaggttc attacaagta tggctatggt cgagacgtct tgtcggatat caatttaacc
     7381 gttccccaag ggtctaaggt ggcttttgtg gggatttcag ggtcaggtaa gacgactttg
     7441 gccaagatga tggttaattt ttacgaccca agtcaagggg agattagtct gggtggtgtc
     7501 aatctcaatc agattgataa aaaagccctg cgccagtaca tcaactatct gcctcaacag
     7561 ccctatgtct ttaacggaac gattttggag aatcttcttt tgggagccaa ggaggggacg
     7621 acacaggaag atatcttacg ggcggtcgaa ttggcagaga ttcgagagga tatcgagcgc
     7681 atgccactga attaccagac agaattgact tcggatgggg cagggatttc aggtggtcaa
     7741 cgtcagagaa tcgctttggc gcgtgctctc ttgacagatg cgccggtctt gattttggat
     7801 gaggcgacta gcagtttgga tattttgaca gagaagcgga ttgtcgataa tctcatggct
     7861 ttggacaaga ccttgatttt cattgctcac cgcttgacta ttgctgagcg gacagagaag
     7921 gtagttgtct tggatcaggg caagattgtc gaagaaggaa agcatgctga tttgcttgca
     7981 cagggtggct tttacgccca tttggtcaat agctagaaag aggagaggat gaaaccagaa
     8041 tttttagaaa gtgcggagtt ttataatcgt cgttaccata atttttccag tagtgtgatt
     8101 gtacccatgg cccttctgct cgtgttttta cttggctttg caactgttgc agagaaggag
     8161 atgagtttgt ccactagagc tactgtcgaa cctagtcgta ttcttgcaaa tatccagtca
     8221 actagcaaca atcgtattct tgtcaatcat ttggaagaaa ataagctggt taagaagggg
     8281 gatcttttgg ttcaatacca agaaggggca gagggtgtcc aagcggagtc ctatgccagt
     8341 cagttggaca tgctaaagga tcaaaaaaag caattggagt atctgcaaaa gagcctgcaa
     8401 gaaggggaga accactttcc agaggaggat aagtttggct accaagccac ctttcgcgac
     8461 tacatcagtc aagcaggcag tcttagggct agtacatcgc aacaaaatga gaccatcgcg
     8521 tcccagaatg cagcagctag ccaaacccaa gccgaaatcg gcaacctcat cagtcaaaca
     8581 gaggctaaaa ttcgcgatta ccagacagct aagtcagcta ttgaaacagg tgcttccttg
     8641 gccggtcaga atctagccta ctctttttac cagtcctaca agtctcaggg cgaggaaaat
     8701 ccccaaacta aggttcaggc agttgcacag gttgaagcac agatttctca gttagaatct
     8761 agtcttgcta cttaccgtgt ccagtatgca ggttcaggta cccagcaagc ctatgcgtca
     8821 gggttaagca gtcaattgga atcccttaaa tcccaacact tggcaaaggt tggtcaggaa
     8881 ttgacccttc tagcccagaa aatcttggag gcagagtcag gtaagaaggt acagggaaat
     8941 cttttagaca aggggaaaat tacggcgagt gaggatgggg tgcttcatct taatcctgag
     9001 accagtgatt ctagcatggt tgcagaaggt gccctactag cccaacttta tccatctttg
     9061 gaaagagaag ggaaagccaa actcacagcc tatctaagtt caaaagatgt agcaagaatc
     9121 aaggtcggtg attctgttcg ctatactacg actcatgatg ccgggaatca acttttccta
     9181 gattctacta ttacaagtat tgatgcgaca gctactaaga ctgagaaagg gaatttcttt
     9241 aaaatcgagg cggagactaa tctaacttcg gagcaggctg aaaaacttag gtacggggtg
     9301 gaaggccgct tgcagatgat tacgggcaag aaaagttatc tacgttatta tttggatcaa
     9361 tttttgaaca aagagtaatg ttcgtgtttt tagagttaaa taatttttaa actgtgagaa
     9421 agattcttct tgcagttttt tctttacaat ttttgaaaaa tatctactat ttattcggtt
     9481 aaattcttgt gttttttggt tttttgtggt aaaatgtgct caagtaatac gaaaggcgaa
     9541 ctttaaaatg tcaaaacaat tgatctattc gggaaaagct aaagatatct atacaactga
     9601 ggatgaaaat cttattattt caacttacaa ggaccaggcg actgctttca atggtgtcaa
     9661 gaaggagcag attgcaggta agggagtctt gaataatcag atctcatctt ttatttttga
     9721 gaaattaaat gcggctggtg tggcgactca ctttgtggag aaactttcag acacggaaca
     9781 actcaataaa aaggttaaga ttattccttt ggaagtcgtg ctccgcaact atactgctgg
     9841 ttccttttca aaacgttttg gtgtggatga aggaatcgcc ttggagactc cgattgtcga
     9901 attttactac aaaaatgatg atttggatga tccatttatc aatgatgagc atgtgaaatt
     9961 cctacagatt gcggatgacc agcagattgc ctacttgaag gaagaaacgc gtcgtatcaa
    10021 tgaactattg aaagtctggt ttgctgagat tgggcttaaa ttgattgact ttaagctaga
    10081 gttcggtttt gacaaggatg gcaagattat cttggcagac gaattttcac cagataactg
    10141 ccgcttgtgg gatgctgatg gcaaccacat ggataaggat gttttccgta gaggattggg
    10201 agaactaacc gacgtttatg agattgtttg ggaaaagttg caggaattga aataatctgt
    10261 ttgcaatgga aaaccttcgt ctctcaacta aaaggactca ggctgaaaag gtcccccaga
    10321 ccttttcact ctgtagagaa ctaggtgaac taaccgatgt ttacgaaatt gtctaggaaa
    10381 agttgcaggg tttaaaataa caacctcaag gctgtttggg aatattgcaa gagctgaaat
    10441 aaaggaataa gaattgatgg ataaacgtat ttttgttgaa aaaaaggctg attttcaggt
    10501 caagtcagag agtttggtta gagagctcca gcacaacttg ggactgtcaa gcttgaaaag
    10561 tattcgtatt gtgcaagtat atgatgtatt tgacttggct gaggacttgt ttgcacctgc
    10621 agagaagcac attttctctg agcaggtaac cgaccatgtt ttagatgaag tatctgtgca
    10681 ggcggatctt gctaactatg ctttctttgc cattgaaagt ctaccagggc agtttgacca
    10741 gcgtgcagct tcgtcacagg aagccttgct tttgttggga agttcgagtg acgtgacagt
    10801 caacacagcc caactttact tggtgaataa agatattgat gtgactgagt tggaagctgt
    10861 caaaaactac ctgctcaatc cagttgattc tcgtttcaag gatatcacga cagggattgc
    10921 caagcaggag ttttcagagt cagacaagac cattccaaaa ttgactttct ttgaaagcta
    10981 tacagcagaa gactttgctc gctacaaggc cgaacaaggg atggccatgg aagtggatga
    11041 tttgctcttt atccaagact actttaagtc aatcgggcgc gtgccaactg agactgaact
    11101 caaggttttg gacacttact ggtctgacca ctgccgtcat acgacttttg agacagagtt
    11161 gaaacacatc gacttttcag cttctaaatt tcaaaagcaa ttgcagtcaa cctatgacaa
    11221 gtatattgcc atgcgcgagg aattaggtcg gtctgaaaaa ccacaaacct tgatggatat
    11281 ggcgactatt ttcggtcgtt atgagcgtgc taatggacga ttggatgata tggaagtctc
    11341 tgacgaaatc aatgcctgct cagttgaaat tgaagtggac gttgatggtg tcaaggaacc
    11401 ttggctcctc atgtttaaaa atgaaaccca caaccatcca acagaaattg agccatttgg
    11461 tggagcggct acctgtatcg gtggagctat tcgtgatccg ttgtcaggcc gttcctatgt
    11521 ttaccaagcc atgcgtattt caggtgctgg tgatattaca gcaccgattt cggaaactcg
    11581 tgctgggaaa ttgccacaac aagtcatttc taaaacagca gctcatggtt attcttcata
    11641 tggtaaccag attgggcttg ccacaaccta cgttcgtgaa tacttccacc caggctttgt
    11701 agctaaacgt atggaacttg gtgccgttgt tggtgcggct cccaagggca atgttgtccg
    11761 tgaaaaacct gaagcaggtg atgtgatcat ccttctcgga ggcaaaacag gtcgtgatgg
    11821 tgtcggtggt gcgacgggct cttctaaggt tcaaacagtt gagtctgtag agactgctgg
    11881 tgctgaggtt caaaaaggaa atgccatcga agaacgcaag attcagcgcc tcttccgtaa
    11941 tggcaatgtc actcgtctga tcaagaagtc caatgacttt ggggcaggcg gcgtctgtgt
    12001 ggctatcggt gaattggcag acggtcttga aatcgacctc aacaaggtgc ctcttaaata
    12061 ccagggcttg aatggtacag aaattgccat ctctgaatca caagaacgga tggcggtcgt
    12121 ggttcgtcct gaagatgtgg atgccttcgt tgccgaatgt aacaaagaaa atattgatgc
    12181 tgttgtggtg gcgacagtaa ctgaaaaacc aaatcttgtc atgaactgga atggtgagac
    12241 aatcgttgac ttggagcgtc gtttccttga caccaatggt gtgcgcgtgg ttgtcgatgc
    12301 caaagttgtg gacaaggatg tcaaactccc agaagagcgt caaacatctg ctgaaacact
    12361 ggaatcagat acccttacgg ttctatctga cctcaaccat gcaagtcaaa aaggattaca
    12421 gactgtcttt gactgctctg ttggacgctc aacggttaat cacccacttg gtggtcgtta
    12481 ccaactcaca ccaactgagg catctgtgca gaaattgcca gttcaacacg gtgtgactca
    12541 tactgcgtcg gtcattgctc aaggtttcaa ctcatatgta gctgaatggt ctccatacca
    12601 cggtgctgct tatgcggtta tcgaagcaac tgctcgtttg gtggctgctg gtgccaactg
    12661 gtctaaggct cgtttctctt accaagaata tttcgagcgg atggacaagc aagcagagcg
    12721 ttttggtcag ccagtagccg cccttctagg ctctattgaa gctcagattc aacttggctt
    12781 gccatctatc ggtggtaagg actccatgtc tggtaccttt gaagaattga ccgttccgcc
    12841 aaccttggtt gcctttgggg tgacgacggc agatagccgt aaggtgctct ctccagaatt
    12901 taaagctgtt ggggaaaata tctactacat cccaggtcaa gccctctctg cagagattga
    12961 ttttgacttg attaagaaaa attttgctca gtttgaagca agccaagctg accataaagt
    13021 gacatctgca tcagctgtca aatacggtgg tgtagttgaa agtttggctc ttgctacctt
    13081 tggaaactat attggtgcag aggtgacctt gcctgaactt aaaacagctt tgacagctca
    13141 attaggcggc tttgtcttca catctcctga agaaattgct ggagtagaga agattggaca
    13201 aacgaaagca gactttacac tgactgtcaa cggtgtgaag ctagatggac acaagcttga
    13261 cagtgcattt caagggacat tggaagaagt ttacccaaca gaatttaccc aagcgaaaga
    13321 actagaagaa gtaccagctg tggcatcaga tgttgtgatt aaagccaaag aaaaggttga
    13381 aaaacctgtg gtttacatcc cagtctttcc aggaaccaac tcagaatatg attcagctaa
    13441 ggccttcgaa aaagaaggtg cagaggtcaa tttggtgcca ttcgtgacct tgaatgaaga
    13501 agctattgtc aagtcagttg aaactatggt tgacaatatc gacaagacta atattctctt
    13561 ctttgccggt ggattctcgg ctgcggatga accagatggt tcagctaagt ttatcgtcaa
    13621 tatcctgctt aatgaaaaag tgcgtgtggc tattgatagc tttatcgccc gtggtggctt
    13681 gattatcggt atttgtaatg gattccaagc cttagtcaaa tcgggtctcc taccatacgg
    13741 aaactttgaa gatgctaaca gtactagtcc aaccctcttc tacaatgatg ccaaccaaca
    13801 cgtggccaag atggtggaaa ctcgcattgc caataccaac tcaccatggt tggctggtgt
    13861 gcaagtgggc gatatccacg ctattcctgt ttcgcacggt gaagggaagt ttgtcgtgac
    13921 ggctgaggaa tttgcagagc tccgtgacaa tggacaaatt ttcagccaat acgttgactt
    13981 taacggtaaa ccaagtatgg attctaagta caatccgaat ggttctgtcc atgccatcga
    14041 aggaattacc agcaagaatg gtcaaatcat cggtaagatg ggccactcag aacgttatga
    14101 ggatggtctt ttccaaaata tcccaggcaa taaagaccaa cacctgttcg catcagcggt
    14161 taaacatttc actggaaaat aagacttaca gattttctaa tagatagtat cagtaatgta
    14221 aaagtcatgt aaatctagct cttgatgatt acaaatgaaa attaggtata aaaaatgaca
    14281 tacgaagtaa aatctcttaa tgaagaatgt ggtgttttcg gtatttgggg acatccagat
    14341 gctgctaagt tgacctactt tggactccac agtcttcaac accgtggtca ggagggggca
    14401 ggaatcctct ccaacgatca aggacaactg aagcgccatc gtgacatggg gcttttatca
    14461 gaagttttca gaaatccatc taatttggat aaattgacag gagctggtgc gattgggcat
    14521 gtgcgttatg cgactgctgg cgaagcttct gttgataaca tccaaccctt cctcttccgt
    14581 tttcacgata tgcagtttgg tttggctcat aatggaaatc tgaccaatgc agcctctctc
    14641 aagaaagaac tggaacaaag aggagcaatt ttcagcgcga cttcggactc tgaaatcttg
    14701 gctcacctca ttcgtcgcag tcataatcct agcctgatgg gcaaaatcaa ggaagcgctc
    14761 agccttgtca aaggtggttt tgcctatatc ttgctgtttg aggacaagtt gattgcggct
    14821 cttgacccta atggctttcg tccgctttct atcgggaaaa tggccaacgg agcggtggtt
    14881 gtttcctctg aaacctgtgc ttttgaggtc attggtgccg agtggatttg tgatttgaag
    14941 ccaggtgaga ttgtgatcat tgatgacgag ggcattcagt atgacagcta tacagatgat
    15001 acccagttgg cgatttgttc tatggagtat atctactttg cccgccctga ttctaatatc
    15061 cacggtgtca atgtccatac ggcacgtaag agaatgggag cgcaattggc gcgagaattt
    15121 aagcatgagg cagatattgt agttggtgtg cccaattctt ccctaagcgc ggctatggga
    15181 tttgcggaag aatcaggctt accaaatgaa atgggtctga tcaaaaacca atacacccag
    15241 cgaactttta tccaaccgac tcaagaattg cgggagcaag gagtgcggat gaaactgtct
    15301 gctgtttcgg gtgttgtcaa aggcaaacgt gtggtcatgg tggatgattc cattgtacgt
    15361 ggaacaacct ctcgtcgtat cgttcagctc ttgaaagaag cgggtgcgac tgaggttcac
    15421 gttgccattg gaagtcctgc actagcgtat ccatgtttct acgggattga tatccagacc
    15481 cgtcaggagc tgattgcagc caatcatacg gtcgaagaaa ctcgccaaat cattggtgcg
    15541 gacagtctga cttatctttc aattgatggc ttgattgagt cgattggtat cgaaacagat
    15601 gcgccgaacg gtggtctctg tgtcgcttac tttgacggtg actacccaac gcctctctat
    15661 gactacgaag aagactatcg tagaagtttg gaagaaaaga ccagttttta caagtaggcg
    15721 acagattctc cattaaagaa aaggaaaaaa taaatgacaa ataaaaatgc atatgcccag
    15781 tcgggtgtgg atgttgaagc gggttatgaa gttgttgaac ggattaaaaa gcacgtggcc
    15841 cgtacggaga gtgcaggtgt catgggagct cttggtggct ttggtggtat gtttgatctt
    15901 tccaagactg gggttaaaga acccgtcttg atttcaggga ctgacggtgt cggaaccaag
    15961 ctcatgttgg ctatcaagta cgacaagcac gataccatcg ggcaggactg tgtggccatg
    16021 tgtgtcaacg acatcattgc tgcaggtgcg gaacccctct attttctcga ctacgtagcg
    16081 acagggaaga atgaaccagc taagctagaa caagtggttg ctggtgtggc agaaggttgt
    16141 gtgcaggctg gtgctgccct catcggtggg gaaacggctg aaatgccggg catgtacggc
    16201 gaagacgact atgacttggc tggttttgcg gtcggtgtgg ctgaaaaatc tcaaatcatt
    16261 gacggttcaa aggtggtaga gggagatgtt cttctcggac ttgcttcaag tgggattcac
    16321 tcaaatggtt actctttggt tcgtcgtgtc tttgcggatt acacaggtga ggaagtccta
    16381 ccagaattgg aaggcaagaa acttaaggaa gttctacttg agccgactcg tatctatgtc
    16441 aaggctgtct tgccgctcat caaagaagag ttggtcaacg gcattgccca catcacaggt
    16501 ggtggcttta tcgaaaatgt ccctcgtatg tttgcagatg acctagctgc tgaaattgat
    16561 gaaagcaaag ttccagtgct tccaattttc aaagcccttg aaaaatatgg tcagattaaa
    16621 cacgaagaaa tgtttgaaat cttcaatatg ggtgtgggac ttatgttggc ggtcagccct
    16681 gaaaatgtag agcgtgtaaa agaattgttg gatgaagcag tctatgaaat tggtcgcatc
    16741 gtcaagaaag aaaacgaaag tgtcattatc aaatgaaaaa aatagcggtt tttgcctctg
    16801 gtaatggctc aaattttcag gtgattgccg aagaatttcc agtggagttt gtcttttcag
    16861 accatcgtga tgcctatgtg cttgagcgtg caaagcagct cggcgttctg tcctatgctt
    16921 ttgaactcaa ggagtttgag agcaaggcag actacgaagc agcccttgtc gaactcttgg
    16981 aagaacacca gattgacttg gtttgcctag caggctacat aaaaatcgtt ggaccaacct
    17041 tattgtcggc ttatgaaggt cggattgtca atattcatcc agcctacttg ccagaatttc
    17101 caggagctca tgggattgag gatgcttgga atgctggcgt gggtcagtct ggtgtgacca
    17161 ttcactgggt ggattcgggt gtggatacag gccaggtcat caaacaggtt cgtgtgccac
    17221 gactagctga tgataccatt gacagatttg aagctcgcat ccatgaagca gagtacaggt
    17281 tgtatctgga agtagtgaag gctctattta cagattgact ttttgatgat tcatatgata
    17341 tctttgattt taaattggag tcagtgtttg ttgaagacgg cttcaaacgg aggtatttgt
    17401 aatgttagaa tctaaaaaaa caactcgata tgtattttat gtctatctga tgttattaac
    17461 ttggggaatc ttatttaagt ttgaaacaaa tcctgaattt atagcatttt tcttagctcc
    17521 aaggtatatc aattggattc cattttcaga accactaata gtcgatggaa aaattgtttt
    17581 tgctgaaatg ttatttaatc tgatttcctt tattccatta ggtgtttgtt tccctttgat
    17641 aaaaactaat ttatctagtt taagaatagt cgggacaggt ttcttgatta gtttattgtt
    17701 tgagtgctta cagtatattt tagcaatagg tataacagat ataacggatt tgactttaaa
    17761 tacgctaggt gtctgtgtag gcttactgat ttatcaaatt tttataagag tgttcaaatc
    17821 acagactaga aaatggatca atatcttagg tatgcttagc cttggttttg cttatcttgt
    17881 tttactgtta ctgcatttaa ttggtgttta actaatgatt aaaaaggaga atataatgac
    17941 taaacgcgtc ttaatcagcg tctcagacaa agcgggcatt gttgaatttg cccaagaact
    18001 caaaaaactt ggttgggaga ttatctcaac aggtggaact aaggttgccc ttgataatgc
    18061 tggggtggat accattgcta tcgatgatgt gactggtttc ccagaaatga tggacggtcg
    18121 tgtgaagacc ctccacccaa atatccacgg agggcttctc gctcgtcgtg acttggatag
    18181 ccacttggaa gcggctaagg acaacaagat tgagctcatt gaccttgtgg tggtcaacct
    18241 ttacccattt aaggaaacta tccttaaacc agatgtgact tatgctgatg cagttgaaaa
    18301 tatcgatatt ggtgggccat ctatgcttcg ttcagcagcg aaaaatcatg ccagtgttac
    18361 agttgtggta gatcctgctg actacgctgt ggttttggac gaattggcag caaacggcga
    18421 aacctcttat gaaactcgcc aacgtttagc agccaaagta tttcgtcaca cagcggctta
    18481 tgacgccttg attgcaaaat acttcacagc tcaagtgggt gaaagcaagc ctgaaaaact
    18541 cactttgact tatgacctca agcaaccaat gcgttacggt gagaatcctc aacaagacgc
    18601 ggacttttac cagaaagctt tgcctacaga ttactccatt gcttcagcca aacagctcaa
    18661 cgggaaagaa ttgtcattta ataatatccg tgatgcagat gctgctatcc gtatcatccg
    18721 tgacttcaaa gatagtccaa ccgttgtggc tctcaaacac atgaatccat gtggaattgg
    18781 tcaagctgat gacatcgaga ctgcttggga atacgcttat gagtctgacc cagtgtctat
    18841 ctttggtgga attgtcgtcc tcaaccgtga ggtggatgct gcgacagctg agaagatgca
    18901 cggcgttttc ctcgaaatca tcattgcacc aagctatacg gatgaagcgc tagccatttt
    18961 gatcaataaa aagaaaaact tgcgtatcct tgccttgcca tttaatgctc aagaggctag
    19021 cgaagtggaa gcagaataca caggtgtagt cggtggactt ctcgtgcaaa atcaagacgt
    19081 ggtcaaggaa agcccagctg actggcaagt ggtgaccaaa cgtcagccaa ccgagacaga
    19141 agcgactgct cttgagttcg cttggaaggc tatcaagtac gtcaaatcaa atggcattat
    19201 cgtgaccaac gaccacatga cacttggtgt tggtccaggt caaaccaacc gtgtggcttc
    19261 tgttcgcctt gccattgacc aagccaaaga tcgtctggac ggggcggtcc ttgcttcaga
    19321 tgccttcttc ccatttgcgg ataacgtgga agaaatcgcc aaagcaggaa ttaaggccat
    19381 catccagccc ggtggctcag tccgtgacca agaatctatc gaagccgctg acaagtatgg
    19441 cttgaccatg gtcttcacag gagtgagaca ttttagacat taagaagata aaagggaaga
    19501 aaacagtttc tttccttttt tggcttaaaa tgctaactga aacaagatta aaacgaactt
    19561 ttttgatata atgttggtaa ataattcgca aaagaggttg aggaatgaaa ctgcttgttg
    19621 tcggttctgg tggtcgtgag catgcgattg ctaaaaagtt acttgaatca aaagacgtgg
    19681 aaaaagtctt tgtagctcct gggaatgatg ggatgactct ggatggtttg gaattggtaa
    19741 atatctctat ttccgaacat tctaaattga ttgacttcgc aaagaccaat gatgttgctt
    19801 ggacctttat cggcccagat gatgcccttg ctgctggtat cgtggatgat tttaaccaag
    19861 ctgggcttaa ggcctttggt ccgactaggg ctgcagcgga gctggagtgg tccaaggatt
    19921 ttgccaagga aatcatggtc aaatatggtg tttcgacagc agcctatggc acattttcag
    19981 attttgagga agcaaaggcc tatatcgaaa agcatggtgc gcctatcgta gtcaaggcgg
    20041 atggcttggc gcttgggaag ggtgtcgtcg ttgctgagac ggttgagcaa gcggtcgaag
    20101 ccgctcatga gatgcttttg gacaataaat ttggtgactc aggtgcgcgc gtggttattg
    20161 aggaattcct tgaaggagag gaattttcac tctttgcctt tgtcaatggt gataagttct
    20221 acatcatgcc aacggctcag gaccacaaac gtgcctacga tggcgacaaa gggcctaaca
    20281 cgggtggtat gggtgcctat gcgccagttc cacacttacc acagagtgta gttgatacag
    20341 cggttgacac cattgtcaag ccagttctag aagggatgat taaagaaggt cgcccttatc
    20401 tgggagttct ttacgcaggg cttatcctga cagctgatgg accgaaagtc atcgagttca
    20461 acgctcggtt cggagatcca gaaactcaga ttatcttgcc tcgcttgacc tctgactttg
    20521 ctcaaaatat cacagatatc ctggatagca aggagccaaa tatcacgtgg acggacaagg
    20581 gtgtgactct gggtgtggtt gtcgcatcca agggctaccc gctagattat tcaaagggtg
    20641 ttgagttgcc agtcaaaacc gatggtgaca tcattaccta ctatgcaggg gctaagtttg
    20701 cggaaaatag cagagcgctg ctctcaaacg gcggacgagt ttatatgctc gttaccacag
    20761 cagataccgt caaagaagcc caagccagca tctaccaaga actatcccaa caaaaaatag
    20821 aaggactctt ctaccgaaca gatatcggaa gcaaggcaat taagtaaaga tataagaata
    20881 acgcgacgca gtcgccaaac acgataatgg tcgtcgtggt gaaaagacca gaacagtgaa
    20941 tgttctggtc agggggaaac tttgagacct taggctcaaa gtttaggaat gaaaccgaag
    21001 gtttgcttcc gcctccatca cctaagacca ttatcaaaaa gaaaaataaa aattcacaaa
    21061 atacgttaat ggtcgtatgg tttgcgagcg ttagcgagct aatatggagc aattaccgcc
    21121 gttgtgaaag aacgattgga tgataatcca atcgttcagg gaaattggaa gaccttgggt
    21181 ttccaattta ggcatgagac acctttggtg gctgctgccg tccctcacaa gctaaggtga
    21241 ttgttgaaaa agaggaaaaa ggagaagaaa tgaaaccagt aatttccatc atcatgggct
    21301 caaaatccga ctgggcaacc atgcaaaaaa cagcagaagt cctagaccgc ttcggtgtag
    21361 cctacgaaaa gaaagttgtt tccgcacacc gtacaccaga cctcatgttc aaacatgcag
    21421 aagaagcccg tagccgtggc atcaagatca tcatcgcagg tgctggtggc gcagcccatt
    21481 tgccaggtat ggtcgctgct aaaacaatcc ttccagtcat tggtgtgcca gtcaactctc
    21541 gtgctcttag tggagtggat tcactctatt ctatcgttca gatgccgggt ggggtgcctg
    21601 ttgcgaccat ggctatcggt gaagcaggtg cgacaaatgc ggccctcttc gctctccgtc
    21661 tcctctcagt agaggatcag tctatcgcga cagcattggc agatttcgca gaagaacaag
    21721 gaaaaatcgc agaggagtcg tcaaatgagc tcatctaaaa caatcggaat tatcggtggc
    21781 ggtcaactgg gtcagatgat ggccatttct gctatctaca tggggcacaa ggttatcgcg
    21841 ctggatcctg cggcggattg cccggcctct cgcgtggcgg aaatcattgt ggcaccttat
    21901 aacgatgtgg acgccctccg tcagttggca gaccgttgcg atgtcctcac ttacgagttt
    21961 gaaaatgtcg acgctgacgg tttggatgtc gttatcaagg atggacaact ccctcaagga
    22021 acagatctgc tccgcatttc gcaaaatcgt atttttgaaa aggacttttt gtcaaacaag
    22081 gctcaagtca ctgtggcacc ctacaaggtc gtgacttcta gcctagactt ggcagatatc
    22141 gacttgtcga aaaactatgt ccttaagatc gcaacaggtg gttatgatgg acacgggcaa
    22201 aatgtcattc gttcagcaga cgatttggaa gaagcctatg cattagccga ctcagcagct
    22261 tgtgtcttgg aagaatttgt caattttgac cttgagattt ctgtcatcgt gtcaggaaat
    22321 gggaaggagg tgacgttttt cccagttcag gaaaatatcc accgcaacaa tatcctgtct
    22381 aagaccatcg taccagcccg tatttctgaa agtctagcag acaaggctaa agctatggca
    22441 gtgcgaatcg cagaacaact caacttgtct ggaactctct gtgtggaaat gtttgcgaca
    22501 gctgatgaca tcattgtcaa tgagattgct ccacgaccac acaactcagg ccactactct
    22561 attgaagcct gtgacttttc acaatttgac acgcatatat taggtgttct gggagcacca
    22621 ttgccagcca tcaaactaca tgcgcctgcc gtcatgctta acgttctcgg ccagcatgtt
    22681 gaggccgctg aaaaatatgt cacagaaaat ccaagcaccc acctccacat gtatggtaaa
    22741 atagaagcaa agcataatcg taagatggga catgtgactt tgtttagtga tgtaccggat
    22801 agtgtggaag agtttgggga agggattgat ttttaggaca agtctatgat acaaattatc
    22861 gttaatgcat ttattgaaaa ggataagact ggagcagttg ttgaagtgtt gtatgctagt
    22921 gctgaccaag ataaggtaca agctaaatat gaagaactag ctgcacaata ccccgaaaat
    22981 tatttagcta tctatgatgt accgctggat acggatttga atacactaga tcattacccg
    23041 tctgtgttta ttggaaaaga ggagtttgag tagaaatctt ggtttaccta gatagcttat
    23101 tcccaacagc ttaagaagaa aggaaagatt aacacatgat caaccgttac tctcgccctg
    23161 agatggcgaa tatttggagt gaagaaaata aataccgtgc ttggcttgag gtggaaatcc
    23221 tctctgacga ggcatgggct gagttggggg aaatccctaa ggaagatgtg gctttgattc
    23281 gcaagaaggc ggactttgac atcgaccgta ttttggaaat tgagcaggag acgcgccacg
    23341 atgtggtggc tttcacgcgt gcggtttctg agactcttgg tgaagagcgc aagtgggttc
    23401 actatgggtt aacttctacc gacgtggtgg atactgccta tggttacctc tacaagcagg
    23461 ccaacgacat catccgtcgt gaccttgaaa acttcactaa tatcatcgct gacaaggcca
    23521 aggagcacaa gttcaccatc atgatggggc gtactcatgg tgtgcacgct gagccgacaa
    23581 cttttggtct taaattggca acttggtata gcgaaatgaa acgcaatatc gagcgcttcg
    23641 agcatgcggc tgctggtgta gaagctggta agatttctgg tgcggttggg aactttgcca
    23701 atatcccacc atttgtagag gagtatgtct gcgataaact tggcatccgt gcccaagaaa
    23761 tctctacaca agtccttcct cgtgaccttc acgctgagta ctttgcggtt cttgccagca
    23821 ttgcgacttc aatcgaacgt atggcgactg agattcgtgg tctacaaaaa tctgagcaac
    23881 gcgaagtaga agagttcttt gctaaagggc aaaaagggtc ttcagcaatg cctcacaaac
    23941 gcaacccaat cggttctgaa aatatgactg gtctggcgcg tgtcattcgt ggtcacatga
    24001 ttacggctta tgaaaacgtc gctctctggc acgaacgcga tatttctcac tcatcagctg
    24061 agcgtatcat cacaccagat acgaccattt tgattgacta catgctcaac cgttttggaa
    24121 atatcgtcaa gaacttgaca gtcttcccag aaaatatgat ccgaaacatg aactcgactt
    24181 ttggtcttat ctttagccaa cgggctatgt tgacattgat tgaaaaaggc atgacccgtg
    24241 agcaagccta tgacttggtg caaccaaaaa cagcctactc ttgggacaac caagtagact
    24301 ttaaaccact tcttgaggca gattcagaag taacatcacg tctcactcaa gaagaaatcg
    24361 atgaaatctt caacccagtt tattacacca aacgagtgga tgatatcttt gaacgtcttg
    24421 gactaggtga ttaattaaaa aataaacagc gagcttcaat ctcgctgttt attttttatc
    24481 gaaaagactt agtcttcttt tcttttagtg agtccatagg ctgctagtgt ggacatgagt
    24541 cctgcgacta ctagtcctgc agaatcgtga gttcctgttt caggaagttt tttctctgtt
    24601 accacaggag ctggatcttg aggaagagct ttgctttcct cagcaggagc agttgatgga
    24661 gctggttggc ttgggatttc tagttttggt ttttcttcag caatagcggc ttgtccgttt
    24721 tcatcgccta catgtgttac catagttccg acttcgacta tttgagtaac ggcttcctgt
    24781 gctacgacac tatttacaag tgttttcact tccttaccat cggcagaagt gctcacagag
    24841 tagaagttgc tacgatgtcc attgacgccc ttagtaatga cttgtgtttt tcctttgagt
    24901 aagagtggat tttcacgagt cactgtggta aatggaattt cttctttttg gatatccagt
    24961 ctaggtttta cctcagtagt tggtgcaaga ccactttcat cacccttgtg agttacagga
    25021 gcgccaactt caaccacttg gtttataact tctttggtta cctggctatc aaggactgtt
    25081 tctgttgttt ttccattttc agtgagtaca gagatgtaat gagttcgttc acctttgact
    25141 cctgctgtga taatattttc ctgaccagct gggaggttag gattttcttt cttgataact
    25201 tcaaatggaa tttcttcagt tcttgtgatg agttctggtc tggtttcaac attggcagcc
    25261 acttcatttt catctaggct tcctgaatga gttgcagctg gtttgaggcc ttgaagagcg
    25321 gcttttaggt tggctacaag tgtgtcaagc tcagcttgtt tattacggtt gaggttgtaa
    25381 tttagagctg ttttagctgc gtcaagggcc tcaagacttt ctttactata tccttctaag
    25441 tttgtaggaa ttttagctaa ttcttcgcgg agagcattat aattagcacg gaagtagtct
    25501 ttgttgtggt ctgcaaaggc agtcatgagt tcaaagattt cctcttcctt gtactcagcg
    25561 cttggtctat ctgcccagat tgaaagcata cttccgactg ttggaagatc tacttcagga
    25621 tatttggtag aagctagttg attgaatggt gtttttccag tattctcaat agctttcttg
    25681 aggaaaccac caccatcttc tggtttttga ccaagaatgt agtaccagtc accgttggta
    25741 ttcaagaatt tatagccttt gcttgctagg tattgaggtg atgcgaggtt atatccccac
    25801 cagcctttag accagtaaga aatcaagaca tctttgtcaa actgaacatc gtccttgtct
    25861 tcatagtaga agccatcgtt gaaggccatt ggttgaagcc ctctttcttt ggccatagct
    25921 gcgagggtgt tggcatattc ggcaaatttg ccatagagtt gataccactt gaggtagtac
    25981 cagccttggg cactagtcgc atcgttggcg tattcgtcag taccaaagtt gaaaatcttt
    26041 gttttacctg caaagaagtc catgtattta ccgatgaggg cttttacaaa gttcatcgct
    26101 tcttcgtttt tcaagtccat agttgttttt gaaactttat caaagtgggc ttgaggattt
    26161 ttaataccta atttttccat ggcaaccagc atagcatcca tgtgacctgg actgttaata
    26221 gctgggatga gaccgatgtc cttagattta gcgtattcaa ttagctctgt tacttctgcc
    26281 tgtgttagtg cagtaccgtt tggatcgtcg tagtaagctt tagttccttc gataatagct
    26341 tttttaacgt catcactagc ataggttttt ccgttggcag taatggtcat atcatcgagt
    26401 agaaagcgaa gtccgtcatt tcctagaagg agatggacat cagaatatcc gagctcactg
    26461 gccttgtcta cgatgcgttt gagctggttc agagtaaagt atttgcgtcc agcatcgatt
    26521 gagattacct tgtttttggc aagtttttca acctcacgtt tagcttcttc ttcttttaga
    26581 gcttcaggcg tgagggtcaa gttgttgaca gtttcttgaa gtttagcaat ggcttgatca
    26641 atcgtatctt gttgggcacg gctaaggttg ctatcgagag agcgaatagc tttttcagct
    26701 tcttttacgg ccgtgacgct ttctgcagta taacggttca ggtcttttgg tacctcgtta
    26761 agtgcttgct ctgcagattc ataatcagct gcgaagtatt cagcgttggc atttgcaaaa
    26821 tgacgcatga gtttgaagag gcgtgatggt gaataacgtg cagatggagt gtcagcccaa
    26881 gcagctacca taccaccgat gattgggata tcagctcctt ctgtttttgg tacagaagtg
    26941 attggtgtgt ttttaatacc attgagcccc tgatcgagat tgtaccagcc ttggccatca
    27001 gcgtttcgtc caagaacgta gtaccaagca tcattggtat taaggatttg gtgacctttt
    27061 tcagctagta gtttagaaga agcgacatcg tagcctcccc aaccaccagt ccacatagaa
    27121 acgatgatgt ctttgtcaaa actaccaaag cttgtgtcgc tattgtagta gataccgtcg
    27181 ttaaaagcca ttggtttgag accgtgcgat tttacaatac gagcgaggtc attggcgtag
    27241 gcaataaatt tttcatagcc ttttacaggg tagccttcgt ttggatagta tttatcagct
    27301 tgaagcacac tccaaccttt agcatctgtc gcatcattgg catattcatc aagtccgatg
    27361 ttgaagattt cagtcttttt cgcgaaataa gcagcatact tgtcgataag ggcttttgta
    27421 aaagcgacag cttgttcgtt gtcaagatcg acagtacggg ctgatttctt cccaaaatag
    27481 ctaaagttag ggttttggat tcccaattct ttcatggcat tgagaatcgc atccatgtgt
    27541 ccaggactat ttactgtcgg aatgagaccg atacctttat ctttggcata gttaatcaga
    27601 tctgtcattt gactttctgt taagtgattg ccgtttggat cgttgtaata atcatttgta
    27661 cctttttcaa tggcgcgttt gacatcgtca ctggcatagg tcttgccgtt agctgtgatg
    27721 ctcatatcgt ccaacatgaa acggagtcca tcatttccga ctaataggtg taaatcagtg
    27781 tagccataat gtttcgcttt atcgatgatt tccttgagtt gttctggtga gaaatattta
    27841 cgtccagcat caatagaaac aattttcttt ttcgctagtt tttcatttac agttgcagca
    27901 cgttcctttc ctgcctctgt ttccggtttg tcagcctctg ctttcgcttc atctttttta
    27961 gctggtttat ccttgtcagt cttgtctgta tttgactctt tagaatcaac ctctttcgct
    28021 tcttcctttt tagggctagc ttcttctgcc tttttattag cagtttcttt ttcagcagaa
    28081 gtttgagtta ccacctctgc tttatcacta ggagttgaac taacttcctc ttgtggtttt
    28141 tcttctgttt ttggaagact agctacctta tcagtagctg gagtttctgt ttctacagtt
    28201 tttggagctt ctggttgaag ctctgcttta ggtgtttcct cagtccgatt ttcggatgat
    28261 tgaggggaat cagaaactgt atggatggtc ggttggtttt ctgtagtagt agtaactcca
    28321 tcggctgcaa cagtctgtgc ttggaaggca aatccaatta gaacagaagc tgctcctaca
    28381 gcgtatttac gaatagaaaa acgctgttgt ttttcatgtt tcattgcaaa acctcctgat
    28441 tgcattgtta tattgatagc gattatataa atcaacgcct ttattttatt tcttatatta
    28501 acgagagtca agaggagatg acaaaaaact ataataagta taaaaaaata taaaatttaa
    28561 gcttaagatt tcagattggt cggaaaaaat acgtatatat atctagtata atttttggtt
    28621 ctatttctat aaaatattcc acaaattata gaatcttcca aaaataggta agcgctacct
    28681 ttttggtgtg gtataataag catagaaaaa gcccgagcga ttaggctcag gctttcttct
    28741 tagtgatcac ggtcacatga gatgaattta atcttgtagt aatcagatcg tttgtaagtt
    28801 tcactgtatt ctaaaacttg gccagttgat tcgagtttgg tgattttagt ttgtaggaca
    28861 gtagggaatt gttcatcgac tccgaggact gaagccgcat gttctggagt tggaaagact
    28921 atttcgttga tttcttcaaa gtgttcatca ttcatgtgaa tgtggtagtc taacttgaaa
    28981 cgattataga tagaactata gtattcaagg tttggataat ttgcgttgat atattgttct
    29041 gggatgtagg atgtatggta gatataaacg acactgtttg attcgcggat acgttcaatc
    29101 ttgtagtaga attgatcgcc gcgtagaccc aatttttcca ggtaaacaag cttgtttccg
    29161 cgttcaattg aaagaacagt taccttatca tctttagcat tgaagagttc aatatctgaa
    29221 aactctacaa gcttgtgttt gcgtgcacgt gaaacgaagg ttccttttcc ttgttggcgg
    29281 acaatatagc catctttggc aaggtcgttt aaggcgcgaa caactgtgat agagctgaca
    29341 tcgtacattg aaatgagttc tgcttcagta taaaatttat ctccactgct aaactgccca
    29401 gagatgattt tattttttaa ttcgtctttt atgtattgat atttgggaat tgccatattt
    29461 ttacctctat tttccttctc catagaaaat tttaccataa aagcgaaaaa aatagtagtc
    29521 ttttgaataa aaaattagaa taatagtttg aaaaattaag ctatataggg attgatcata
    29581 ttttataaat gtattctata caaaattatt ttaggtccta tattccaaat ttaaagagcg
    29641 tttgaaatgg gtctaaaaat gtttgaaact aattgaatgt gtgtataata gtaaaaatgc
    29701 agtaaatatc ccgacaattt ctattgacag ttcaaacaga ttggtttata attaatataa
    29761 caacaaatga aagcgcaaac tttcgcggtc ggaaggtagt tttatgacac gatttgagat
    29821 acgagatgat ttctatctcg atggaaaatc atttaagatt ttatctggtg ccattcatta
    29881 ttttagggtt cctccagagg attggtatca ttcgctctat aacttgaagg ctcttggttt
    29941 taatacggta gagacttatg ttgcttggaa tttacacgag cctcgtgaag gtgagtttca
    30001 ttttgaaggt gatctggatt tagagaaatt tctccaaata gcgcaggatt tgggtctcta
    30061 cgcaattgtg cgtccgtctc catttatctg tgcggaatgg gaattcggtg gcttaccagc
    30121 ttggctcttg accaagaaca tgcgaattcg ctcatctgac ccagcatata tcgaggcagt
    30181 tggtcgctac tatgatcagt tattgccaag actggtgcct cgtttgttgg acaatggtgg
    30241 caatattctc atgatgcagg ttgaaaatga gtatggttct tacggagaag ataaggctta
    30301 cctgagagcg attcgacagc taatggaaga gtgtggcgta acctgtcccc tctttacatc
    30361 agatggtcca tggcgagcta ctctgaaagc tggaacctta attgaagagg acctctttgt
    30421 aacaggaaac tttggttcta aggcacctta caacttttcg cagatgcagg aattctttga
    30481 tgaacatggt aagaaatggc cactcatgtg tatggagttc tgggatggtt ggttcaatcg
    30541 ctggaaagaa ccgattatca cacgggatcc taaggaattg gcagatgcag ttcgagaggt
    30601 tttggaacaa ggctctatca atctttacat gttccacggt ggtacaaact ttggtttcat
    30661 gaatggttgc tcagctcgag gaactttgga cctgccacaa gttacgtctt atgattacga
    30721 tgcccttctg gatgaagaag gaaatccaac tgctaaatat cttgcagtca agaagatgat
    30781 ggcaacacat ttttcagagt atccgcagtt ggaaccactc tacaaagaga gtatggagtt
    30841 ggatgctatt ccactagttg aaaaagtttc tttgtttgaa accttagata gcttgtcaag
    30901 tcctgtagaa agtctctatc ctcaaaagat ggaggagctg ggacaaagtt atggctacct
    30961 actttatcga acagaaacaa actgggatgc agaagaagaa agacttcgta tcattgatgg
    31021 tcgagatagg gcccagctgt atgtcgatgg tcagtgggtt aaaactcaat atcagacaga
    31081 gattggggaa gatatttttt atcaaggtaa aaagaaaggg ctatctaggt tagatatctt
    31141 gatagaaaat atggggcgtg tcaactatgg gcataagttc ttagcggata cgcaacgtaa
    31201 gggaattcgg acaggggtct gtaaggatct gcatttctta ctaaactgga aacactatcc
    31261 actcccacta gacaatcctg agaaaattga tttttcaaaa ggatggactc aaggacaacc
    31321 agccttttac gcttatgact ttacagtcga agagccaaaa gatacttacc tagacttgtc
    31381 tgagtttggt aagggggttg cctttgtcaa tgggcagaat ctaggacgtt tttggaacgt
    31441 tggcccaact ctctcacttt atatccctca tagctatctc aaggaaggtg ccaaccgcat
    31501 cattatcttt gaaacagaag gtcaatataa agaagagatt catttaactc gtaaacctac
    31561 actaaaacat ataaaggggg aaaacttatg acaattgtag gatgccgtat tgatggacgt
    31621 ttgatccacg gacaagtagc caatctttgg gctggaaaac taaatgtttc acgcattatg
    31681 gttgtagacg acgaagttgt caacaacgat attgaaaaga gtggtttgaa acttgcgaca
    31741 ccaccaggtg tgaaattgag tattttgcca gttgagaaag ctgcagccaa tattcttgct
    31801 ggcaaatacg atagccaacg tctctttatc gtggctcgta aaccagaccg cttccttggt
    31861 ttggtagaag caggtgtacc acttgaaacc cttaatgttg ggaatatgtc tcaaacacca
    31921 gaaactcgtt ctattacacg ttctatcaac gtagtagaca aggatgtgga agacttccac
    31981 aaactggcag aaaaaggtgt taaacttact gctcagatgg ttccaaatga tccaatttca
    32041 gactttttga gcttattaaa ataggaaaaa aatttttagg aggtcattgt tatgatacaa
    32101 tggtggcaaa ttttacttct cactttgtac tcagcttatc aaatctgtga tgagttgacg
    32161 atcgtttcat ctgcaggttc ccctgtattt gctggtttca ttactggttt aatcatggga
    32221 gatgtgacta ctggtttact tatcggtggt aacttgcaac tgttcgttct tggggttggt
    32281 accttcggtg gtgcttctcg tatcgacgca acttctggtg cggttcttgc gacagccttc
    32341 tctgtttcac aaggaattga tgcaccgctt gccattacta caatcgctgt accagtagca
    32401 gctctcttga cttacttcga cgttcttggt cgtatgacta ctaccttctt cgctcaccgt
    32461 gtggatgctg caatcgaacg ctttgactat aaaggtattg aacgcaacta cttgcttggt
    32521 gcgattccgt gggctctatc tcgtgccctt ccagtcttct ttgcccttgc ttttggtggt
    32581 gcctttgtac aatcagtagt agacttcgtt gaagcctaca aatgggttgc agatggcttg
    32641 acacttgcag gacgtatgct tccaggtctt ggatttgcaa tcttgcttcg ttaccttcca
    32701 gttaaacgta accttcacta ccttgctatg ggatttggtt tgacagctat gttgactgtt
    32761 ctttactcat atgtaacagg tcttggtggc gctgttgctg gtatcgtagg tactcttcct
    32821 gctgaagttg ctgaaaaaat tggtttcgtg aacaacttca aaggtttgtc tatgattggt
    32881 atttctatcg taggtatttt ccttgcagtg cttcacttca aaaatagcca aaaagtagct
    32941 gtagcagcac cttctacacc atcagaaagt ggggaaatcg aagatgacga attctaatta
    33001 caaacttaca aaagaagatt ttaatcaaat caacaaacgt agcttgttta ctttccaatt
    33061 aggttggaac tacgaacgta tgcaagcttc tggttacctt tacatgatct tgcctcagtt
    33121 gcgtaaaatg tatggtgatg gaactcctga attgaaagaa atgatgaaag ttcatactca
    33181 attcttcaat acttcaccat tcttccatac cattatcgct ggttttgacc ttgccatgga
    33241 agaaaaagat ggtgtaggtt caaaagacgc cgttaacggt atcaagacag gtttgatggg
    33301 accattcgct cctcttgggg atacaatctt tggttcactt gtacctgcta tcatggggtc
    33361 agtcgcagca actatggcta tcgctggcca accttggggg atcttccttt ggattgcagt
    33421 tgcagtagcg tatgacatct tccgttggaa acagttggaa tttgcttaca aagaaggggt
    33481 taaccttatc aacaacatgc aaagtacctt gacagctttg attgacgctg catctgtact
    33541 tggtgtcttc atgatgggtg ctcttgtagc aacagtgatt aactttgaaa tttcttacaa
    33601 gttgccaatc ggtgaaaaga tgattgattt ccaagacatc ttgaaccaaa tcttcccacg
    33661 tttgcttcca gcaatcttta ctgcctttat cttctggttg cttggtaaga aaggtatgaa
    33721 ctctactaaa gctatcggta ttattatcgt acttgctttg gctctttctg cccttggtca
    33781 ctttgcactt ggaatgtaat tccttatgac taaatcatta attttggtga gccatggtcg
    33841 cttctgtgag gagcttagag gtagcacaga aatgattatg ggcccacaag acaacattta
    33901 cacagtagct cttcttccag aagatggccc agaagaattt actgctaaat ttgaagctgt
    33961 tattgaagga ttggatgatt tcctagtctt tgcggatctt ctcggtggga caccttgtaa
    34021 tgtggtgagt cgcttgatca tggaaggtcg tgatattgac ctttacgcag ggatgaatct
    34081 tccaatggtg attgaattta tcaatgcgag ccttacaggc gcagatgcgg actacaagag
    34141 ccgtgctgca gaaagcattg tgaaagttaa tgacctgtta gcgggcttcg atgatgacga
    34201 agatgaataa tactcttcga aaatctcttc aaactacgtc aacgtcgcct tgccgtaggt
    34261 atatgttact gacttcgtca gtcttatccg gcaacctcaa aacggtgttt tgagctgact
    34321 tcgtcagtct tatccggcaa cctcaaagca gtgctttgag cagcctgcgg ctagtttcct
    34381 acagatttta gttggaactc gattcaattc atgtgacaac gtgaaaatcg ttagagcatt
    34441 ttatatagaa tatacatggg aatgtagctt actcccattc ccatatttaa tagaaaaaga
    34501 ggaactcaat gctacattat acaaaagaag acttgctcga attgggtgca gaaatcacta
    34561 cgcgtgaaat ctaccaacag cctgatgtat ggagagaagc ttttgaattt tatcaagcaa
    34621 aacgtgaaga aattgcagcc ttcctacaag aaatcgctga taaacatgac tatattaagg
    34681 ttatcttgac aggtgctggg acttctgctt atgtgggaga taccttgcta ccttatttta
    34741 aggaagtcta tgacgaacgc aaatggaatt tcaatgctat tgcgacaaca gatatcgttg
    34801 ccaatccagc aacctatttg aaaaaagatg tggcaactgt ccttgtgtct tttgctcgta
    34861 gtgggaactc gcctgaaagt gtggcgactg ttgatttggc caaatccttg gtggatgagc
    34921 tttatcaagt gacgattact tgtgcagcag atggtaaatt ggctcttcaa gctcacggtg
    34981 atgaccgtaa tctcttgctc ttgcaaccag ctgtctctaa tgatgctgga tttgccatga
    35041 cttctagctt tacgtctatg atgttgacag ctctcttggt ctttgatcct acagaatttg
    35101 ctgttaagtc tgaacgtttt gaagttgtat ctagtcttgc ccgtaaagtt ttagacaagg
    35161 cagaagatgt caaagagctt gttgatttag actttaaccg tgtcatctat ctaggcgctg
    35221 gtcctttctt tggacttgct catgaagctc agctcaagat tttggaatta actgctggtc
    35281 aagttgcgac catgtatgaa agcccagttg gcttccgtca cggtccaaaa tctcttatca
    35341 acgacaatac agttgttttg gtctttggta caacgacaga ctacactcgt aagtatgact
    35401 tggacttggt tcgtgaagtt gctggtgacc agattgctcg tcgtgttgtg cttttgagtg
    35461 atcaagcttt tggtcttgaa aatgtcaaag aagtggccct tggttgtggc ggtgtcttga
    35521 atgatattta ccgtgtcttc ccttacatcg tttatgccca actctttgcc ctattgactt
    35581 cactcaaggt agaaaataaa ccagatacac cgtctcctac aggtacagta aaccgtgtag
    35641 tacaaggtgt cataattcac gaatatcaaa agtaagacag tgtttatgaa ttcttgacaa
    35701 gaggatttgt aaattatcag ataaaccata gattgtcagt acgctttcta tggtttgttt
    35761 gcttgagaga aatagtaaaa ggagaacaga atgaaagcat acacagagcg tgtatttgga
    35821 aatgttgagg gcgaggatgt cttggcctat cgatttgaga cagacggtgg ctaccaactt
    35881 gaggttatga cttatggcgc gaccatcttg cgctatgtcg cacctgacaa ggctggaaat
    35941 tttgccaatg ttatcttggg atttgatgac tttgatagtt atgtaggcaa tagtcccaag
    36001 catggagcaa gtgtaggtcc tgtagcgggt cgtattgcag gtgcgacctt tgagctcaat
    36061 ggtaagacct atgaccttga ggttaataat gctagcaact gtaatcacag tggttcaact
    36121 ggttgggatt ccagcttgtt tgaagttgaa gaagtaagcg atcatggctt gactctctac
    36181 acagagcgta cagatgggac aggagggttc cctggaaatc tcaagatttg gatcagttat
    36241 cacttggaag aaactggtgc ctatgaaatc agctacaagg taacgaccga tcaggatacg
    36301 ctggtcaatc caaccaacca cagctatttc aacttgtctg gtgatttcac gcagacgatt
    36361 gaccgtcatg tcttccaact aaacacagag ggcatttact caatcgctcc tgacggtgtt
    36421 cctgccaaaa ctccagaagc caaccgtgat gtggtcaaac acgtctacaa tggtaccttg
    36481 ttgaaggata tctttgcaga agaagatgag caaatccagc tggcatcagg tttggatcat
    36541 ccatttgccc ttcctgcagg ccatgacaat gctggattcc tttatgacca aaattcaggt
    36601 cgcttcctgc ttttcaagac agaagctcct tgctttgtgg tctacacagc aaactttgtg
    36661 gatgaaagtg tcatcatagg aggtcagcca atgctacagc acaatgggat tgctcttgaa
    36721 gcgcaagctt taccagatgc cattcacagt gaccttaaag gccaagtcat tcttaaggct
    36781 ggtcaaacct tcaccagtaa gacacgttat gaacttgttg tgaaataaaa aagctggtca
    36841 aaaagtcttt aaaattaaaa taacgcatat tgtcaggtga tgaaaagttt gatactatgc
    36901 gttttgttat gaaatgattt actttatctt atcctgaaat ggtgttattt ttgagttatc
    36961 tggcttgact ttcttgatgg aaattatata atagttgtaa caataataat tacaacgaga
    37021 aaagaggacc atttatgacc tatgaataca agagtcacat ttatttggca gagacagttt
    37081 taaatgtaaa ggatttggcc agtcaaacag ccttttatca gcaagttatt ggtttagaaa
    37141 tcttatctca aactgagaca gagtccattc taggccttgg tggaaaagtc ttggtacagc
    37201 tgattcaagc acaagagagc ggagaagtga gggaacatta tggtctttac catttggcca
    37261 ttctcttacc cacacgcaag gctttggctg atgtcttgaa acacctgaca gatttacaga
    37321 ttcctcttgt cggcggtgca gaccatggtt acagtgaagc tatttacttg gaagatttgg
    37381 agggaaatgg cattgaactc tatcgagata agccagtttc cacatgggat attcgagaag
    37441 atggacgcat tatcggagtg acggaggctc ttgcggcgca ggacatttat gagttggggg
    37501 aaagagtaga gccctttatc ctggcagaag gtacgagaat ggggcatatt catctttcag
    37561 tcaaggatag tcgaaagtcc agccagtttt atcaaaaggt gttagggcta gaggataaat
    37621 tcagtgtgcc tagcgctagt tggattgcgg ctggagatta ccatcatcat ttagcagtta
    37681 acgaatgggg aggaaaaggt ctggcttcgc gtaagcaagg cttaccaggt ttagcctact
    37741 atgtcatcga agtcgcacat aaaaaagaac tgttaacgat tgcccaacga gcacaagaag
    37801 ttgacgcacc aatcaaatgg atgacatcga gccaattgga aatcacagac tcagatggca
    37861 tcgtgacctg tattcgttta gcaaggtaaa attaggaatt tttaataagt tataagtatt
    37921 gctagtttgc tttttgaacg gtctttggta acagaactgc gtgagctgga tgggtgagaa
    37981 ttttgacaaa gaagctgatt agagatataa tgaagaaaaa tcgagcaagg aaaaagaaat
    38041 gacaaattca aagtatatta ctcgtttgaa acgttcagag ggccagttgc gtgggattca
    38101 aaagatgatt gaaggagatc gtgacgcaac tgacagcagt gagatctagt gtagagcgcg
    38161 tgattgagat gataattacc gaaaatctta ctgaatgtat caatcagcca ctagatgatt
    38221 ctgaagctca aaaggaacgc ctagaaaagg ctatccgata cttgattaaa cggaaataaa
    38281 tgaatgtttt gagacgatat gtgcaaaggt ctattaacta ttagaatagt ttaatgtgag
    38341 tcaaaagaag ttgtaaaaaa tctttaaaat taaaaaaacg catagtatca ggtgttgaat
    38401 gtactgaccc c
//
LOCUS       DAVBOD010000016        36100 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 640-05
            SAMEA1012484-rid20186543.denovo.016, whole genome shotgun sequence.
ACCESSION   DAVBOD010000016 DAVBOD010000000
VERSION     DAVBOD010000016.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012484
            Sequence Read Archive: ERR059358
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 36100)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 36100)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979948.1
            Genome Coverage       :: 595x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:03:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,266
            CDSs (total)                      :: 2,219
            Genes (coding)                    :: 2,091
            CDSs (with protein)               :: 2,091
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 71 of 128
            Pseudo Genes (incomplete)         :: 50 of 128
            Pseudo Genes (internal stop)      :: 33 of 128
            Pseudo Genes (multiple problems)  :: 22 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..36100
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012484-rid20186543.denovo.016"
                     /strain="NIG 640-05"
                     /db_xref="taxon:1313"
     gene            638..952
                     /locus_tag="VQ862_000877"
     CDS             638..952
                     /locus_tag="VQ862_000877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006148869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HET3115245.1"
                     /translation="MELKFVIPNMEKTFGNLEFAGEDKVVQRRINGRLTVLSRSYNLY
                     SDVQRADDIVVVLPAEAGEKHFGFEERVKLVNPRITAEGYKIGTRGFTNYLLHADDMI
                     KE"
     gene            968..1354
                     /locus_tag="VQ862_000878"
     CDS             968..1354
                     /locus_tag="VQ862_000878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000985015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HET3115246.1"
                     /translation="MMRLANGIVLDKDTTFGELKFSALRREVRIQNEDGSVSDEIKER
                     TYDLKSKGQGRMIQVSIPASVPLKEFDYNARVELINPIADTVATATYQGADVDWYIKA
                     DDIVLTKDSSSFKAQPQAKKEPTQDK"
     gene            1383..2768
                     /locus_tag="VQ862_000879"
     CDS             1383..2768
                     /locus_tag="VQ862_000879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000813487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HET3115247.1"
                     /translation="MKQRGKRIRPSGKDLVFHFTIASLLPVFLLVVGLFHVKTIQQIN
                     WQDFNLSQADKIDIPYLIISFSVAILICLLVAFVFKRVRYDTVKQLYHRQKLAKMILE
                     NKWYESEQVKTEGFFKDSAGRTKEKITYFPKMYYRLKNGLIQIRVEITLGKYQDQLLH
                     LEKKLESDLYCELTDKELKDSYVEYTLLYDTIASRISIDEVEAKDGKLRLMKNVWWEY
                     DKLPHMLIAGGTGGGKTYFILTLIEALLHTDSKLYILDPKNADLADLGSVMANVYYRK
                     EDLLSCIETFYEEMMKRSEEMKQMKNYKTGKNYAYLGLPAHFLIFDEYVAFMEMLGTK
                     ENTAVMNKLKQIVMLGRQAGFFLILACQRPDAKYLGDGIRDQFNFRVALGRMSEMGYG
                     MMFGSDVQKDFFLKRIKGRGYVDVGTSVISEFYTPLVPKGYDFLEEIKKLSNSRQSTQ
                     ATCEAEVAGVD"
     gene            2771..2923
                     /locus_tag="VQ862_000880"
     CDS             2771..2923
                     /locus_tag="VQ862_000880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000879507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HET3115248.1"
                     /translation="MLAGVAIATPALNPPYLTGGYKSTGNSQKNIRKSFGYKGFTKFQ
                     RMSNGL"
     gene            2946..4151
                     /locus_tag="VQ862_000881"
     CDS             2946..4151
                     /locus_tag="VQ862_000881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000398284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HET3115249.1"
                     /translation="MEGFLLNEQTWLQHLKEKRLAYGLSQNRLAVATGITRQYLSDIE
                     TGKVKPSEDLQQSLWEALERFNPDAPLEMLFDYVRIRFPTTDVQQVVENILQLKLSYF
                     LHEDYGFYSYSEHYALGDIFVLCSHELDKGVLVELKGRGCRQFESYLLAQQRSWYEFF
                     MDVLVAGGVMKRLDLAINDKTGILNIPVLTEKCQQEECISVFRSFKSYRSGELVRKEE
                     KECMGNTLYIGSLQSEVYFCIYEKDYEQYKKNDIPIEDAEVKNRFEIRLKNERAYYAV
                     RDLLVYDNPEHTAFKIINRYIRFVDKDDSKPRSDWKLNEEWAWFIGNNRERLKLTTKP
                     EPYSFQRTLNWLSHQVAPTLKVAIKLDEINQTQVVKDILDHAKLTDRHKQILKQQSVK
                     EQDVITTKK"
     gene            4194..4415
                     /locus_tag="VQ862_000882"
     CDS             4194..4415
                     /locus_tag="VQ862_000882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_464634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3115250.1"
                     /translation="MNFGQNLYNWFLSNAQSLVLLAIVVIGLYLGFKREFSKLIGFLI
                     IAIIAVGLVFNAAGVKDILLELFNRIIGA"
     gene            4532..5029
                     /locus_tag="VQ862_000883"
     CDS             4532..5029
                     /locus_tag="VQ862_000883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000342537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HET3115251.1"
                     /translation="MDDMQVYIANLGKYNEGELVGAWFTFPIDFEEVKEKIGLNDEYE
                     EYAIHDYELPFTVDEYTSIGELNRLWEMVSELPEELQSELSALLTHFSSIEELSEHQE
                     DIIIHSDCDDMYDVARYYIEETGALGEVPASLQNYIDYQAYGRDLDLSGTFISTNHGI
                     FEIVY"
     gene            5004..5510
                     /locus_tag="VQ862_000884"
     CDS             5004..5510
                     /locus_tag="VQ862_000884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016897981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HET3115252.1"
                     /translation="MGFLKSSIKSVGTLLLADFLFYGVAQSATPIFYERIDYMKKIRS
                     YTSIWSVEKVLYSINDFRLPFPITFTQMTWFVVSLFAVMILGNLPPLSMIEGAFLKYF
                     GIPVAFTWFMSTKTFDGKKPYGFLKSVIAYALRPKLTYAEKKVTLGRNQPQEAITAVR
                     SEFYGISN"
     gene            5494..7941
                     /locus_tag="VQ862_000885"
     CDS             5494..7941
                     /locus_tag="VQ862_000885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_464631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HET3115253.1"
                     /translation="MAYPIKYIENNLVWNKDGECYAYYELVPYNYSFLSPEQKIQVHD
                     SFRQLIAQNRDGKIHALQISTESSIRSAQERSKNEVTGKLKAVAYDKIDQQTDALISM
                     IGENQVNYRFFIGFKLLLNDQEFSMKSLTVEAKNALSDFVYDVNHKLMGDFVSMSNDE
                     ILRFQKMEKLLENKISRRFKIRRLDKDDFGYLIEHLYGQTGTAYEEYEYHLSKKKLDN
                     ETLIKYYDLIKPTRCLVEEKQRYLKIQQEDETVYVAYFTINSIVGELDFPSSEIFYYQ
                     QQQFTFPIDTSMNVEIVANRKALSTVRNKKKELKDLDNHAWQSDNETSSNVAEALESV
                     NELETNLDQSKESMYKLSYVVRVSANDLDELKRRCNEVKDFYDDLSVKLVRPFGDMLG
                     LHEEFLPASKRYMNDYIQYVTSDFLAGLGFGATQMLGENEGIYVGYSLDTGRNVYLKP
                     ALASQGVKGSVTNALASAFVGSLGGGKSFANNLIVYYAVLYGAQAVIVDPKAERGRWK
                     ETLPEISHEINIVTLTSDEKNKGLLDPYVIMKNPKDSESLAIDILTFLTGISSRDGER
                     FPILRKAIRAVTNSEVRGLMKVIEELRVENTPLSTSIADHIESFTDYDFAHLLFSNGY
                     VEQSISLEKQLNIIQVADLVLPDKETSFEEYTTMELLSVAMLIVISTFALDFIHTDRS
                     IFKIVDLDEAWSFLQVAQGKTLSMKLVRAGRAMNAGVYFVTQNTDDLLDEKLKNNLGL
                     KFAFRSTDLNEIKKTLAFFGVDPEDENNQKRLRDLENGQCLISDLYGRVGVIQFHPVF
                     EELLHAFDTRPPVRKEV"
     gene            7944..10122
                     /locus_tag="VQ862_000886"
                     /pseudo
     CDS             7944..10122
                     /locus_tag="VQ862_000886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017646277.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
     gene            10119..11120
                     /locus_tag="VQ862_000887"
     CDS             10119..11120
                     /locus_tag="VQ862_000887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018368130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysozyme/C40 family peptidase"
                     /protein_id="HET3115254.1"
                     /translation="MKLKTLVIGGSGLFLMVFSLLLFVAILFSDEQDSGISNIHYGGV
                     NVSAEVLAHKPMVEKYAKEYGVEEYVNILLAIIQVESGGTAEDVMQSSESLGLPPNSL
                     STEESIKQGVKYFSELLASSERLSVDLESVIQSYNYGGGFLGYVANRGNKYTFELAQS
                     FSKEYSGGEKVSYPNPIAIPINGGWRYNYGNMFYVQLVTQYLVTTEFDDDTVQAIMDE
                     ALKYEGWRYVYGGASPTTSFDCSGLTQWTYGKAGINLPRTAQQQYDVTQHIPLSEAQA
                     GDLVFFHSTYNAGSYITHVGIYLGNNRMFHAGDPIGYADLTSPYWQQHLVGAGRIKQ"
     gene            11117..12052
                     /locus_tag="VQ862_000888"
     CDS             11117..12052
                     /locus_tag="VQ862_000888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HET3115255.1"
                     /translation="MRKEDLMMKFRKNQNKEKQIPKEKKPRVYYKVNPHKKVVIALWV
                     LLGLSFSFAIFKHFTAIDTHTIHETTIIEKEYVDTHHVENFVENFAKVYYSWEQSDKS
                     IDNRMESLKGYLTDELQALNVDTVRKDIPVSSSVRGFQIWTVEPTGDNEFNVTYSVDQ
                     LITEGENTKTVHSAYIVSVYVDGSGNMVLVKNPTITNIPKKSSYKPKAIESEGTVDSI
                     TTNEINEFLTTFFKLYPTATASELSYYVNDGILKPIGKEYIFQELVNPIHNRKDNQVT
                     VSLTVEYIDQQTKATQVSQFDLVLEKNGSNWKIIE"
     gene            12297..12413
                     /locus_tag="VQ862_000889"
     CDS             12297..12413
                     /locus_tag="VQ862_000889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance determinant leader
                     peptide"
                     /protein_id="HET3115256.1"
                     /translation="MILKYPENICMLCMPMVMHKNPSDKSIYHWDFYALLGF"
     gene            12429..14348
                     /gene="tet(M)"
                     /locus_tag="VQ862_000890"
     CDS             12429..14348
                     /gene="tet(M)"
                     /locus_tag="VQ862_000890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011117014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance ribosomal protection
                     protein Tet(M)"
                     /protein_id="HET3115257.1"
                     /translation="MKIINIGVLAHVDAGKTTLTESLLYNSGAITELGSVDRGTTKTD
                     NTLLERQRGITIQTAITSFQWKNTKINIIDTPGHMDFLAEVYRSLSVLDGAILLISAK
                     DGVQAQTRILFHALRKIGIPTIFFINKIDQNGIDLSTVYQDIKEKLSAEIVIKQKVEL
                     HPNMRVMNFTESEQWDMVIEGNDYLLEKYTSGKLLEALELEQEESIRFHNCSLFPVYH
                     GSAKNNIGIDNLIEVITNKFYSSTHRGQSELCGKVFKIEYSEKRQRLAYIRLYSGVLH
                     LRDSVRISEKEKIKITEMYTSINGELCKIDKAYSGEIVILQNEFLKLNSVLGDTKLLP
                     QRERIENPLPLLQTTVEPSKPQQREMLLDALLEISDSDPLLRYYVDSATHEIILSFLG
                     KVQMEVTCALLQEKYHVEIEIKEPTVIYMERPLKKAEYTIHIEVPPNPFWASIGLSVA
                     PLPLGSGVQYESSVSLGYLNQSFQNAVMEGIRYGCEQGLYGWNVTDCKICFKYGLYYS
                     PVSTPADFRMLAPIVLEQVLKKAGTELLEPYLSFKIYAPQEYLSRAYNDAPKYCANIV
                     DTQLKNNEVILSGEIPARCIQEYRSDLTSFTNGRSVCLTELKGYHVTTGEPVCQPRRP
                     NSRIDKVRYMFNKIT"
     gene            14467..14634
                     /locus_tag="VQ862_000891"
     CDS             14467..14634
                     /locus_tag="VQ862_000891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine-rich KTR domain-containing protein"
                     /protein_id="HET3115258.1"
                     /translation="MCPVCGNKTRLKIREDTELKKFPLYCPKCRQENLIEIKQFKVTV
                     ITEPDAKTQSR"
     gene            complement(14694..15047)
                     /locus_tag="VQ862_000892"
     CDS             complement(14694..15047)
                     /locus_tag="VQ862_000892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HET3115259.1"
                     /translation="MRKKEDKYDFRAFGLAIKEARLKRSLTREQVGALIEIDPRYLTN
                     IENKGQHPSIQVLYDLVSLLHVSVDEFFLPANNLVKSTRRLQIEKYMDSFTDKELSLM
                     ESLASGINEARNIED"
     gene            15552..15974
                     /locus_tag="VQ862_000893"
     CDS             15552..15974
                     /locus_tag="VQ862_000893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006733729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HET3115260.1"
                     /translation="MKPSSFQTTIENQFDYICKRAMEDERKNYMLYLSRIAKREVSFS
                     DVGDYLVSQFATTDNYSTDFQIFTLNGLSVGVENDLLSEALRELPDKKREILLLFYFM
                     DMSDSEIADLLKLNRSTVYRHRTSGLALIKKFMEEFEE"
     gene            15971..16201
                     /locus_tag="VQ862_000894"
     CDS             15971..16201
                     /locus_tag="VQ862_000894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002411750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HET3115261.1"
                     /translation="MKTQYPMIPFPLIVKATDGDTEAINQILHHYRGYITKRSLRLMK
                     DEYGNQSMVVDEVLRGRMETRLITKILSFEIK"
     gene            16662..16865
                     /locus_tag="VQ862_000895"
     CDS             16662..16865
                     /locus_tag="VQ862_000895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006730246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excisionase"
                     /protein_id="HET3115262.1"
                     /translation="MKQTDIPIWERYTLTIEEASKYFRIGENKLRRLAEENKNANWLI
                     MNGNRIQIKRKQFEKIIDTLDAI"
     gene            16947..18164
                     /locus_tag="VQ862_000896"
     CDS             16947..18164
                     /locus_tag="VQ862_000896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020220015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HET3115263.1"
                     /translation="MSEKRRDNKGRILKTGESQRKDGRYLYKYIDSFGEPQFVYSWKL
                     VATDRVPAGKRDCISLREKIAELQKDIHDGIDVVGKKMTLCQLYAKQNAQRPKVRKNT
                     ETGRKYLMDILKKDKLGVRSIDSIKPSDAKEWAIRMSENGYAYQTINNYKRSLKASFY
                     IAIQDDCVRKNPFDFQLKAVLDDDTVPKTVLTEEQEEKLLAFAKADKTYSKNYDEILI
                     LLKTGLRISEFGGLTLPDLDFENRLVNIDHQLLRDTEIGYYIETPKTKSGERQVPMVE
                     EAYQAFKRVLANRKNDKRVEIDGYSDFLFLNRKNYPKVASDYNGMMKGLVKKYNKYNE
                     DKLPHITPHSLRHTFCTNYANAGMNPKALQYIMGHANIAMTLNYYAHATFDSAMAEMK
                     RLNKEKQQERLVA"
     gene            complement(18326..18928)
                     /locus_tag="VQ862_000897"
     CDS             complement(18326..18928)
                     /locus_tag="VQ862_000897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000821271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET3115264.1"
                     /translation="MKRIIPVYIFQQVNVLLVSLYLLKFLCIGELTILQIIYGASLIS
                     FLWMYGQRKQVAKVNMETRIKWIGIGFVSLLIISLYFSLIHAQESTNQANLIGLQHQV
                     PWFSFLLFLINASMVEEFLYREILWNLVRKLDIRVALTSVLFALAHHPGTILAWCLYV
                     SLGMFLGMVRYKSDLWGSMGLHLVWNLLVYSLLLFNKNKV"
     gene            complement(18931..19164)
                     /locus_tag="VQ862_000898"
     CDS             complement(18931..19164)
                     /locus_tag="VQ862_000898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HET3115265.1"
                     /translation="MAERFWENLSIILAERNISWIELTRKMFAGEFHYPSELNRLYQK
                     IRHYKMEQRMPQSPWVERIVQVLDLDYEDLFRR"
     gene            complement(19177..19557)
                     /locus_tag="VQ862_000899"
     CDS             complement(19177..19557)
                     /locus_tag="VQ862_000899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3115266.1"
                     /translation="MIDLYLSKNNHRNQLLLEFFQNYGIEVSCHSISEMTRDKLIEMM
                     SYSSDCFEFLSPNLLRFKNRDNLRLTDFIEMILKNPELTIRLPLAVSNKRVYPNLNLE
                     EARALLPRDTKQLIYMAQTHYLSN"
     gene            complement(19550..19999)
                     /locus_tag="VQ862_000900"
     CDS             complement(19550..19999)
                     /locus_tag="VQ862_000900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000645893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3115267.1"
                     /translation="MKALNKESILYCDELETELHDAEMMQLDEQIFLMPNYPCEFEVT
                     FLDYYHKKHNYPLFYESYLQNIMEFLESQDIKNGADAFIDDNHNLVFVLYGQGYRAEG
                     KEGILTTQVTVKAYDEDKKSINFSNLLDSLIVSEYQMEPNLWEVSHD"
     gene            complement(19983..21341)
                     /gene="dcm"
                     /locus_tag="VQ862_000901"
     CDS             complement(19983..21341)
                     /gene="dcm"
                     /locus_tag="VQ862_000901"
                     /EC_number="2.1.1.37"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014947343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA (cytosine-5-)-methyltransferase"
                     /protein_id="HET3115268.1"
                     /translation="MRFIDLFSGIGGFRLGMESVGHECIGFCEIDKFARKSYKSIFQT
                     EGEIEFHDIRDVSDAEFKKLRGKVDIICGGFPCQAFSIAGRRLGFEDTRGTLFFEIAR
                     AAKQIQPRFLFLENVKGLLNHDKGRTFTTILTTLDELGFDVEWQLLNSKDFGVPQNRE
                     RVFIIGHSRKRGTRLLFPFRREGQTTNSETLKTLGNLNPSKSGMSGKVYYSEGLAPTL
                     VRGKGEGFKVAIPCMTPDRLDKRQNGRRFKENQEPMFTLNTQDRHGIVVVGDLPTSFK
                     ETGRVYGSEGLSPTLTTMQGGDKIPKILIPEPIQFLKVREATKKGYAQAEIGDSINLE
                     RPSSQYRRGRVGKGIANTLTTSGQMGVVVASYEGEDKQVYQVAGVLIDGQFYRLRIRR
                     ITPKECFRLQGFPDWAFEAARKVSSNSQLYKQAGNSVTVPVIAAIAKKLKEIEEKDES
                     AK"
     gene            complement(21440..22219)
                     /locus_tag="VQ862_000902"
     CDS             complement(21440..22219)
                     /locus_tag="VQ862_000902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000822769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HET3115269.1"
                     /translation="MKRITANQYQTSERYYKLPKILFEDEKYMDMKLEVKVAYSILKD
                     RLELSLSRGWIDEEGAVYLVFSNSKLMKLLGCSKSKLLSIKKILKEYDLIDEVQQSSS
                     EKGRLANKIYLGELSSTPVGNSNRPSVKKRLGQVENETAPVSHSAPRETEVSETKYSE
                     TDSLFIEDEEDRNTQPILKRKVEKVTKYDRDYIWGLVQDQFRREGFSETASEIAMTDF
                     ERIYQYALDNVRFVRRAEVLAEFVFNGLYSVWNNRVRKGGG"
     gene            complement(22216..22389)
                     /locus_tag="VQ862_000903"
     CDS             complement(22216..22389)
                     /locus_tag="VQ862_000903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000159601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3115270.1"
                     /translation="MTKELQSSRYIVISFLVREMGIDIVEAISLMAELEKSGLVQLES
                     SGDLTLKELGGAL"
     gene            complement(22919..28132)
                     /locus_tag="VQ862_000904"
     CDS             complement(22919..28132)
                     /locus_tag="VQ862_000904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000054791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HET3115271.1"
                     /translation="MSLLKKDKFSIRKIKGIVGSVFLGSLLFAPSVVGASTYHYLDYS
                     SLTQTERDQLKQGRPDESKESYALDYEKDALPNTGSSQSIMTALGLLAIGSLIVIITK
                     DNRNKKIATFLIVGATGLVTLSTASALNLNANIHESGRDGVLQISGYRYVGYLELDDK
                     TVSSVSPASTVSPVEQPKVVTEKGEPEVHEKPDYTQPIGANLVEPEVHEKLAYTEPVG
                     TTGVDENGNLIEPPVNDIPEYTEPVGTTGVDENGNLIEPPVSDIPEYTEPISTVSEVA
                     SEREELPSLHTDIRTETIPKTTIEESDPSKFIGDDSVRQVGEDGERQIVTSYEELHGK
                     KISDPVETVTILKEMKPKILVKGTKEKPKEKTAPVLTLDRTNTNVLNRSATLSYHLVN
                     TDGVTINKITATIKDGNEIVKTVDLTSEQLDKQVEDLKFYKDYKIETTMTYDRGKGEE
                     TATLEEKPLRLDLKKVEIKNIASTNLVKVNDDGTETPSDFMTEKPSDEDVKKMYLKIT
                     SRDNKVTRLAVDKIEEVTEEGKKLYKITAEAQDLIQHTDPTKVRNKYVHYIEKPVPKV
                     DDVYYNFKELVDAMNADKNGTFKIGADLNATNVPTPNKQYVPGTFKGHLSSVDGKQYT
                     IHNIARPLFDRVENGSVKNINLGNVDINMPWADGIAPVANMVKNATVEDVKVTGNVVA
                     NNNIAGIVNKIDSGGQLTNVAFIGNLTGVGDKGQYMAGIAGEIWRGNLAKAYVEADIV
                     ANRARIGGLVAKTDNGNDSMGIGKYGSIRKSVTKGTIKTKVLFETGGFINSNLPFGKL
                     EDNISMMRVENGEEFFGSSDLDYDGGYFTNGWLERNFVVKGVSSGKHSYKRSRDKIKE
                     ISQDEANKRIANFGLTADKYEINEPVVNRLNRLTRREDEYKSTQDYKSERDLAYRNIE
                     KLQPFYNKEWIVNQGNKLAEDSNLAKKEVLSVTGMKDGQFVTDLSDIDKIMVHYADGT
                     KEEMDVTKNTDSKVQQVREYSVSGLGDVVYTPNMVVKNRDKLIADVKSQLSSVELISQ
                     EVRDLMSRRDKPAENTDERKNGYIKDLYLEESFAEVKQNLDKLVKSLVENEDHQLNGD
                     EAAIKSLLKKVETNKAKIMMALTYLNRYYDIKYGDISIKNIMMFKPDFYGKTPSVIDR
                     LINIGSSEKNLKGDRTQDAYREIIAGNTGKSNLRNFLEYNMRLFTEDKDINDWFIHSA
                     KNVYVSEPKTTNTELKDKRHRVFDGLDNGVHGRMILPLLTLKDAHMFLISTYNTMAYS
                     SFEKYGKHTEEARNEFKTKIDEVAHAQQTYLDFWSRLALPNVRDRLLKSQNMVPTPVW
                     DNQTYNGSPVGRRGFDSKGNPIAPIRELYGPTWRHHDRDWRMGAMASIFPNPNNDDKV
                     LFMVTDMISPFGISAFTHETTHVNDRMLYFGGHKHRQGTDVEAYAQGMLQTPDSSTTN
                     GEYGALGINMAYHRPNDGNQWYNPDPDKLKTRDDIDRYMRNYNEAMMLLDHVEADAVL
                     PKIKGDNSKWFKKIDKEMRSKIQYNDLLGPNQWDSIRDLKDEEKVMTLSSVNDLVDNN
                     FMTKHGNPGNGRYRPEDFTPNSAYVNVNMMAGIYGGNTSQGAPGSLSFKHNAFRMWGY
                     YGYENGFISYVSNKYKAEADKNNHGLLSDKLIINKVSKGNFNTLEEWKRHWYGEVLAK
                     AKKGFEAIDIDGVHISNYDELRPLFDKAVEEDLKKPDDFSHTVALKSKVFKALLKNTD
                     GFFNKLFKEDI"
     gene            complement(28176..34655)
                     /locus_tag="VQ862_000905"
     CDS             complement(28176..34655)
                     /locus_tag="VQ862_000905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001845810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HET3115272.1"
                     /translation="MEKYFGEKQERFSFRKLSVGLVSATISSLFFMSVLASSSVDAQE
                     TAGVHYKYVADSELSSEEKKQLVYDIPTYVENDDETYYLVYKLNSQNQLAELPNTGSK
                     NERQALVAGASLAALGILIFAVSKKKVKNKTVLHLVLVAGMGNGVLVSVHALENHLLL
                     NYNTDYELTSGEKLPLPKEISGYTYIGYIKEGKTTSDFEVSNQEKSAATPTKQQKVDY
                     NVTPNFVDHPSTVQAIQEQTPVSSTKPTEVQVVEKPFSTELINPRKEEKQSSDSQEQL
                     AEHKNLETKKEEKISPKEKTGVNTLNPQDEVLSGQLNKPELLYRDETIETKIDFQEEI
                     QENPDLAEGTVRVKQEGALGKKVEIVRIFSVNNEEVSREIISTSTTAPVSRIVEKGTK
                     KAQVIKEQAETGAEHKEVQSGAIVEPAIQPELPAAVLTDKGESAVQPELPEAVVSDKG
                     VPEVQPALPEAVMTDKGDPEQVEPLPEYTGVQAGAIVEPEKVEPEYAGVQAGAIVEPE
                     QVAPLPEYTGVQAGAIVEPEKVEAPKEYTGVQAGAIVEPEKVEAPKEYTGVQAGAIVE
                     PEKVEPSKEYTGVQAGAIVEPEQIAPLPEYTGVQAGAIVEPEKVEALKEYTGKIEQPS
                     AEDTKPNNENTNTPEEMSIQKKSSALINMNFITDSSKVTGVGSATFIAPNVLLTVAHN
                     FINNSTDNTTGEFRGDKSKNVYEWVTPDGQKGTFTANNIHFYNKKDYPKGFIYDLAVI
                     KLPETTGREHVELVKNYSKVNLNDKLNVHGYPAGKYTHLKDATVEMEQEYANNTYGVQ
                     YQGGNPGMSGGGIFNANGEVIGVHQNGAQNRSGGLILSPTQLAWIKSIIAGNEIPPVY
                     DELYRHKDEKKDDAKDEKEVIKKLELRNISSVELYSKDGNKYRHVTSLASLPSNAENY
                     FMKVKSENFKDVMLPVTSITNDTKDNRDVYKIVASANSLIQHENNNVLENYTYYLPKT
                     QQSETGVYTSFKNLVDAMNSNPNGTFRLGATMDAREVELPDGQESYVNNVFHGILVGT
                     NNEKYYAIYNLKKPLFGELNGATVEKLSLKDVNISAKDDTATLAKEANNNTHIDNVHA
                     DGAIAGERSIGGLVSQVNNSTISNSSYTGRITNTYKTVASYQIGGLVGKLSGPRGLID
                     KSFASIDLSSNATQGDQSIGGIVGAVENSALISNSYAEGNLNNVQRFANVGGVVGNLW
                     DPVGGLEKSGRLSNVLSDVNVTNGNAIAGYNFNGIKANGTYSNKNNKVVNVVQEDDEI
                     LTKDSTVQRGEVLEDAQIKEKKATFVSKNTIKTEDFNFSSRYVTDYKNLENADSSKEK
                     VYKNIEKLLPFYNRETIVKYGNLVETSSNLYNKELLSVVPMKDKEVISDINKNKSSIN
                     KLLLYYADNTSETLNVNYQTDFSNVAEYRIGGTNLIYTPNTLLRNYQNILDEVLPALN
                     SVEYKSEAIRKVLDVSKDVSLTELYLEEQFNTTKTNLKDSLTKLLTADAAIAENNNKV
                     IDNYVIEKIKNNKEALLLGLTYLERWYDFKYRDTKAKDLVMYHLDFFGKSNSSALDNV
                     IELGKSGYNNLLAKNNVITYNVLLAKNYKTNNLFDALEKYRKAFVPDKTNNEWFKEQT
                     KAYIVEEKSTIKEVSDKQSIAGSPYSIGVYDRLTSPSWKYPSMVLPLLTLPEKSVFII
                     ANISTIGFGAYDRYRSKEHPAGTDLNDYVEKKAKEAAVRFRDHYDYWYRILDDKNKEK
                     LYRSVLVYDAFRFGTDEKEDKDTYQATFETNHPAIKHFFGPAGNNVVHNSNGAYATGD
                     AFYYMAYRMLDKDGAVTYTHEMTHNSDREIYLGGYGRRNGLGPEFYAKGLLQAPDHPN
                     DPTVTINSILKYDQSEESTRLQVADPTQRFGSVDDLNKYMHNMFDVIYMLEILEGKAV
                     AKLDTNQKYDLLRKIENEYKPDPDGNSVYATNVVRRLKPEELTKLTTFNSLIEHDIIT
                     RRGYVDEATYKRNGYYTINLFSPIYSALSSKIGTPGDLMGRRIAFELLAAKGYKDGMV
                     PYISNQYEKEAKAQGKVITSYGKQIGLVTDEIVLSKVFNNQYNSWIDFKKDMYKERED
                     KFGKLNKVSFIDPNGSWARQQKVTIDNINRLEKMIEDAVKFDAEDEVAKLYPETNSRV
                     LKLKKAIFKAYLDQTGDFRSSIFENKK"
     gene            complement(34864..36042)
                     /locus_tag="VQ862_000906"
     CDS             complement(34864..36042)
                     /locus_tag="VQ862_000906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3115273.1"
                     /translation="MTLPVRKSLHDAVLQASKADTWEQATKEWNEVSLIFNGIGRSNC
                     VCGNAIKYAYELFNGVTGQRLFPIGSDCVRHFHRLSLDQQLEEEEKLLRKVENLTRKA
                     QKKEKIKVNKSDFDERLLKWLWEKGVFKPNRGNQFAPERDYQLFLEVFQGGSWTKAEP
                     KKKARMEEVLEKCIKPFLLGKSDDQLYLVKLGKEKIDYEQELRIQAEKERKKRDKIAK
                     QYADNLVLAMGPAERAYQDYFGFTETLTQEERKWEKILFGKNRAERAIKAKQYQKELE
                     KDQRIASQDPIERKQKQTWLLNSYFRELPEEKARFSRLLLEYRKSGEVPFSTEYLSDH
                     LIDFFYKMKAFEFEIAPEQVRDFLKKSLQEDHRSSAQGSWIEGILLNCLKPFLERLVI
                     "
BASE COUNT        11087 a         6897 c         6461 g        11655 t
ORIGIN      
        1 agtctggtaa cgataaactc cgtgtctgtt agaaaattct cacacacgtc ttgtgccagt
       61 tgcccttcac agggaaatac tctcagtccc tacttacaca ggcacgctaa tcaagacgga
      121 gtggattcaa ttttcaaaga acaggtagct ttattataga gaagagtagt tgaaattttt
      181 atcacatttt ttatttttct gtagagctaa attcatacta aacaaagatt ttgaaataaa
      241 agactaacat tgttacataa cgttagcatt tcatttccct aaaataagct aattttgtct
      301 aaaaaatagc ataaaaatct agttatccgc ataaaaactg gacttatcac actttatcaa
      361 ggtcaaaacc actcaattta ctactaattt actacttatg aatgagcttt gatacgacga
      421 tttatccttg aaaagtgaag atataaagat acttccaata aaatttgaat atttaatagg
      481 tagacacttc aaaaaatgag gtgtctattt ttttacccga ttttgaaagg aagtgaactt
      541 atgaaaacaa aaaatcaaga atcaaaaggt cgttccccac tctttaagac catcaaacat
      601 tcattcagcc aataaaaaag aaaggatagg taaaaatatg gaacttaaat ttgtgattcc
      661 caacatggaa aaaacattcg gcaatttaga atttgctggc gaggataaag tcgttcagcg
      721 aagaatcaac ggacggctaa ctgtcttatc aagaagctat aatctctatt ctgatgttca
      781 aagagcagat gatattgtgg tggtgcttcc tgctgaagct ggcgaaaaac atttcggctt
      841 tgaggaacgt gtgaagttag tcaatccacg tattaccgca gagggctaca aaatcggcac
      901 tcgtggtttt acaaattacc ttttacatgc tgacgacatg ataaaagaat aaagaaagag
      961 aggaaaaatg atgagattag caaatggcat tgtattagat aaagacacga cttttggaga
     1021 attgaaattc tctgctctac gtcgtgaagt gagaatccaa aatgaagacg ggtcggtttc
     1081 agatgaaatc aaggaacgta cctatgactt aaaatccaaa ggacaaggac gcatgattca
     1141 agtaagtatt cctgccagcg tgcctttgaa agagtttgat tataacgcac gggtggaact
     1201 tatcaatccc attgcggaca ccgttgctac tgccacctat caaggagcag atgttgactg
     1261 gtatatcaag gcagacgata ttgtgctgac aaaggattct agttcattca aagctcaacc
     1321 acaagcaaag aaagaaccga cacaagacaa atagtcgcta ggtagaaagg agactttttc
     1381 gcatgaaaca gcgtggtaaa aggattcgcc catctggtaa agatttagtc tttcatttta
     1441 cgatagcgtc actcctgcct gttttcctgc tggttgtcgg actgtttcat gtgaagacaa
     1501 tccagcagat caactggcag gattttaacc tatcacaagc agataagatt gacattccct
     1561 atttaattat cagtttcagt gtcgcaattc ttatctgctt gctggtagcg tttgtattca
     1621 aacgggttcg ctatgatacg gttaaacaac tttaccaccg tcaaaaactg gcaaagatga
     1681 tacttgaaaa caagtggtat gaatctgaac aggtcaaaac agagggtttc tttaaagata
     1741 gtgctggtcg tacaaaggaa aagataacct acttccctaa aatgtattat cgacttaaaa
     1801 atggcttgat acagatacgg gtggaaatca cgctgggaaa atatcaagac caactcttac
     1861 acttggaaaa gaaattagag agtgacttgt actgtgagct gacggataaa gagttaaagg
     1921 attcctatgt ggaatatact ttgctctatg acaccatagc cagtcgtatt tctattgatg
     1981 aagtagaagc taaagatggt aaacttcgct taatgaaaaa cgtatggtgg gaatatgata
     2041 agctccctca tatgttgatt gctggtggta caggtggcgg taaaacttac tttatactga
     2101 cactgattga agccttgctt catacagatt caaaactgta tattcttgac ccgaaaaatg
     2161 ctgaccttgc ggacttaggt tctgtgatgg caaatgtcta ctatagaaaa gaagacttgc
     2221 tttcttgcat tgaaacattc tatgaagaaa tgatgaaacg tagtgaggaa atgaagcaga
     2281 tgaagaacta taagactggc aaaaattatg cttacttagg tctcccggca cacttcttaa
     2341 tctttgatga atacgtcgct ttcatggaaa tgctgggaac aaaagaaaac accgcagtta
     2401 tgaataagct gaaacagatt gtcatgttag gtcgtcaagc tggcttcttt ctaatactgg
     2461 cttgtcaacg tccagacgca aaatatttag gcgacggaat ccgtgatcag tttaatttca
     2521 gagtggcttt aggtcgtatg tctgaaatgg gctatggcat gatgtttggc agtgacgtac
     2581 aaaaggattt cttcttaaag cgaatcaaag gtcgtggcta tgttgatgta ggaacaagtg
     2641 tcatatcaga gttttatact ccccttgtac caaaaggata tgatttcttg gaggaaatta
     2701 aaaagttatc caacagcaga cagtccacgc aggcgacgtg cgaagcggaa gtcgcaggtg
     2761 tggactgatc ttgctggctg gtgtggcaat agccacgcca gcacttaacc ccccgtatct
     2821 aacagggggg tacaaatcga caggaaacag tcaaaaaaac attagaaaat cctttggtta
     2881 caagggattt acaaaatttc agcgtatgtc aaatgggctt taaaagttga catacgcctt
     2941 tttgattgga gggattttta ctgaatgaac aaacttggtt acagcattta aaagaaaaac
     3001 gcttggctta tggactatct caaaaccgtt tagctgttgc gactggtatt acaaggcagt
     3061 atctaagcga tattgaaaca ggaaaagtca agccatcaga ggatttacag cagtcccttt
     3121 gggaagctct ggaacgcttc aatcccgacg ctccccttga aatgctgttt gattatgtaa
     3181 ggattcgctt tccgacaaca gacgtacagc aggtggtcga aaacatctta caactgaaac
     3241 tgtcctattt tcttcatgag gactatggtt tctattctta ttcagagcat tatgctttag
     3301 gcgacatatt cgtcctttgc tcccatgaac tggacaaagg agttctggtg gaattgaaag
     3361 gtcgtgggtg cagacaattt gaaagctatc ttctggcaca acaaagaagc tggtatgagt
     3421 tctttatgga cgttttggtg gctggcggtg tgatgaaacg ccttgacctt gccattaacg
     3481 ataagacagg gattttgaat atccctgtac tcactgaaaa gtgccaacag gaagaatgta
     3541 tctccgtctt ccgcagtttt aaaagctatc gcagtggcga actggtacgc aaagaggaaa
     3601 aggaatgtat gggaaacacc ctctatatcg gttcattaca aagtgaagtt tatttctgta
     3661 tctatgaaaa ggactacgag cagtacaaga aaaatgatat tcccattgaa gacgcagaag
     3721 taaaaaaccg ttttgagatt cgattgaaaa atgagcgtgc ctattatgca gtccgtgatt
     3781 tactcgtcta tgacaatcca gagcataccg cctttaaaat tatcaatcgg tatatccgtt
     3841 ttgtagataa agacgattcc aaacctcgtt ctgattggaa actgaatgaa gaatgggctt
     3901 ggtttattgg gaacaatcgt gaacgattaa aactaaccac aaaaccagag ccttactcct
     3961 tccaaaggac gctgaactgg ctatctcatc aagttgcccc gaccttaaag gttgcgatta
     4021 aacttgatga aatcaaccag acgcaggttg taaaagacat tctcgaccat gcgaaactga
     4081 cagaccgaca caagcagatt ttgaagcaac agtcagtaaa agaacaggac gtgataacaa
     4141 caaaaaaata actcaaatac aaattcattg aatatagaga ggagaacatt tttatgaatt
     4201 ttggacaaaa cctttataac tggtttctat caaacgctca atcactggtg cttttagcaa
     4261 tcgttgtgat tggcttgtat cttggcttca agcgtgagtt tagcaaactg attggctttt
     4321 taattattgc gattattgcg gttggcttag tcttcaacgc tgctggagta aaagacattt
     4381 tactagagct attcaatcgc attattggtg cttaaataaa accgttcttt tgtggaatat
     4441 aagtggtttt cttatgttcc gcaaaggaat ggtacaccaa acgaagtgcg gtagggattt
     4501 ttgaatctct acaaagaaag gacgtgaata tatggacgat atgcaagtct atattgcgaa
     4561 tttaggcaaa tacaatgagg gcgaattggt cggtgcgtgg tttacctttc ccattgactt
     4621 tgaggaagtc aaagagaaaa tcggcttgaa tgatgaatat gaggaatacg ccattcatga
     4681 ctacgagtta ccctttacgg ttgacgaata cacttccatt ggcgaactca atcgactatg
     4741 ggaaatggta tcggaattac ccgaagaatt acaatcggag ctatctgctc tgctcactca
     4801 tttttcaagc attgaagaac taagcgaaca tcaagaggat attatcattc attccgattg
     4861 tgatgatatg tatgacgtgg cacgctacta cattgaagaa acgggtgctt taggcgaagt
     4921 accagctagt cttcaaaact atattgatta tcaagcctat ggtcgggatt tagacctttc
     4981 aggaacgttt atctcaacca atcatgggat ttttgaaatc gtctattaaa tctgtcggta
     5041 cattactact ggcagatttt ctattttacg gggtggctca atcagctacc cctatttttt
     5101 atgaaaggat tgattacatg aagaaaatac gaagctatac cagtatctgg tctgtggaaa
     5161 aggtactgta ttctatcaat gattttagac ttccgtttcc cataaccttt acgcaaatga
     5221 catggtttgt cgtgtcactc tttgcagtga tgatacttgg caacttgccc cctctttcca
     5281 tgatagaggg agcatttctc aaatactttg ggattcctgt ggctttcaca tggtttatgt
     5341 ctacaaaaac ttttgatggt aaaaagcctt atggattttt gaagtctgtc attgcttatg
     5401 cactgcgacc aaagctgacc tatgcagaaa aaaaagtaac gcttggcaga aaccagccac
     5461 aagaagccat tacagcagtt aggagtgaat tttatggcat atccaattaa atacattgaa
     5521 aacaatctcg tctggaataa agacggggaa tgttatgctt actatgagct tgttccttac
     5581 aattactcat ttctaagtcc agaacagaaa atacaagtgc atgattcttt cagacagctt
     5641 atcgcacaaa atcgtgatgg caaaattcat gctttacaaa tcagtacaga atccagcata
     5701 cgttctgcac aagagcgttc caaaaatgaa gtcactggca agctcaaagc ggttgcctat
     5761 gacaaaatcg accaacagac agacgcttta atatccatga ttggcgaaaa tcaagtgaac
     5821 taccgtttct ttatcggctt taagttgctt ctcaacgatc aggagttttc tatgaaaagt
     5881 cttaccgttg aagcaaaaaa tgctttgtct gattttgtct atgatgtgaa ccataagctg
     5941 atgggcgatt ttgttagtat gagtaatgat gaaatcctgc gttttcagaa gatggaaaag
     6001 ctcttagaaa ataaaatctc tcgtcgtttc aaaatccgca ggttagataa ggacgacttc
     6061 ggctatctga ttgaacacct ttacggacag acaggcactg cctatgaaga gtatgagtac
     6121 catctatcaa agaaaaagct ggataatgaa acgctgatta aatactatga cttgattaag
     6181 cctactcgct gtttggtgga agaaaaacag cgatatttga aaatccagca ggaagatgaa
     6241 accgtctatg tagcttactt taccattaac agcattgtcg gagaactgga cttcccgtcc
     6301 tctgaaatct tctactacca gcaacagcaa tttacattcc cgattgatac gtcaatgaat
     6361 gtggaaattg tagcgaatcg taaagcccta tctactgtcc gcaataaaaa gaaagaactg
     6421 aaagacttgg ataaccacgc ttggcaaagt gataatgaaa ccagctccaa tgtggcggaa
     6481 gctctggaaa gtgtgaatga gctggaaacc aatttagacc aaagcaagga atctatgtac
     6541 aagctgtctt atgtggtaag ggtatcagca aatgatcttg acgaactcaa acgtcgttgt
     6601 aatgaagtga aagattttta tgacgattta agcgtaaaac tggtacgacc atttggggat
     6661 atgctcggct tacatgaaga atttttacct gccagcaagc gttatatgaa tgattatatt
     6721 caatacgtga cctctgattt cctcgctggt ttaggttttg gtgctactca aatgctgggg
     6781 gaaaatgagg ggatttatgt tggctacagc ttagatactg gacgcaatgt ctatctgaaa
     6841 cctgctcttg ccagtcaagg ggttaagggt tcagtaacca atgcgttagc gtcggctttt
     6901 gttggttcgc tgggtggtgg taaatccttt gcgaataacc ttatcgtcta ttatgcggtg
     6961 ctttatgggg cacaagcagt gattgtagac ccaaaagcag aacgtggcag atggaaagaa
     7021 accttgccag agatttccca tgaaatcaat atcgtcactc tgacttctga tgagaaaaac
     7081 aaaggcttac ttgaccctta tgtgattatg aaaaatccca aagattctga atcactggct
     7141 attgatattc tgacattcct tacggggatt tcctctcgtg atggggaacg cttcccaatc
     7201 cttagaaaag ccattcgtgc agtaaccaat agtgaagtac gagggttgat gaaagtgatt
     7261 gaggaattac gggttgagaa tacgccacta agtaccagta tagccgacca tatcgaaagt
     7321 tttacagact atgactttgc acatttatta ttcagtaatg gttatgtgga gcagtctatc
     7381 agcttagaaa aacaactgaa cattatacag gttgcggact tggtacttcc cgacaaggaa
     7441 acttcctttg aggaatatac cactatggag cttttatccg ttgctatgct gattgtcatt
     7501 agtacctttg ctttagactt tatccataca gaccgaagca ttttcaagat tgtagattta
     7561 gacgaagcat ggagcttttt acaggtagca caaggaaaaa cactatctat gaagctggtt
     7621 cgggctggtc gtgctatgaa cgctggggta tatttcgtga cccaaaatac agacgacctc
     7681 ttagatgaaa aactgaaaaa taacctcggc ttaaaatttg catttcgttc cactgacctt
     7741 aacgagatta aaaagacctt agcctttttt ggtgtagacc cagaggacga aaacaatcag
     7801 aagcgattgc gtgatttgga aaacgggcaa tgccttatca gtgatttata tggtcgtgtc
     7861 ggtgtgatac agttccaccc tgtatttgaa gaactgctcc atgcctttga taccagacca
     7921 cctgtgcgaa aagaggtgta aatgtgaaac catcaatagt aaacagaata aaatcaaact
     7981 ggacgctgaa acgtctaggt aaagtggcaa tgacagtggc tttcacactt gtgattgcca
     8041 tttttctttt agccatgctg ggaacggtgg ttcaagctgc gggcttggta gatgatacgg
     8101 tcaatgtggc aaatgaatac agccgatacc cacttgaaaa ctatcaactg gatttttatg
     8161 tggataatag ctggggctgg cttccgtgga actggtcgga cgggattgga aaacaggtca
     8221 tgtatggact atatgccatt accaatttta tttggacaat cagtttgtat gtttccaatg
     8281 cgacaggtta cttagtacag gaagcctatt ccttagactt catttccgct acagcagatt
     8341 ccattggtaa gaatatgcag accttagctg gtgtgagtgc aaacggattt tcaacagagg
     8401 gtttctatgt tggattcctc ttactcttga ttttggttct tggggtttat gttgcctata
     8461 cgggactgat aaagagagaa accacaaagg caattcatgc cattatgaat tttgtgctgg
     8521 tgtttatcct atcggcttcc tttattgcct acgctcccga ctacattaaa aaaatcaatg
     8581 acttttcatc agacatcagt aatgccagtt tatcacttgg cacgaagatt gtcatgcccc
     8641 attccgatag tcaaggcaag gacagcgtgg acttaatcag agatagcctg ttttccatac
     8701 aggttcagca accgtggcta ctgcttcaat acaacagttc agacattgaa agtatcggta
     8761 ttgaccgtgt ggaaagcctg ctctccacca gcccagattc caacaatggc gaagacagag
     8821 aaaaaaattg ttgcggaaga aattgaagac agaagcaata ccaatctaac cattacaaag
     8881 accattaacc gtttaggtac agtcttcttc ctatttgtct tcaatattgg gatttccata
     8941 tttgtattcc tattaacagg aatcatgatt ttctcgcagg tactttttat catctatgct
     9001 atgtttctgc ctgtgagctt tattttaagc atgattccat catttgatgg tatgtcaaaa
     9061 cgagccataa caaagctctt taataccatt ttgacacgag ctggaatcac attgattatt
     9121 acgacagcat ttagtatttc aaccatgctc tataccttat cggctggtta tccgttcttt
     9181 ttgattgctt ttctacagat tgtgaccttt gcaggaatct acttcaagct gggcgattta
     9241 atgagtatgt tttctctaca gagtaacgat tctcaaagtg tgggaagtcg tgtgatgaga
     9301 aaacctcgta tgcttatgca cgctcacatg caccgtctac agcggaaact tggacgttcc
     9361 atgactactc taggggctgg gtctgccatt gttacaggta aaaaaggaca gtcgggttcg
     9421 gggagttctg caaggacaca agcagatcac tcccgaccag acggaaagga aaaatcaaca
     9481 cttggaaaac gtatcggtca aaccatcggt acagtagctg ataccaaaga cagaatggta
     9541 gacactgcta gtggtttgaa agaacaggtt aaagatttgc cgaccaatgc aagatatgca
     9601 gtatatcaag gaaaatccaa agtaaaagag aatgtccgtg atttaaccag tagtatttct
     9661 caaaccaaag cggacagagc cagtggacgc aaggaacagc aggaacaaag gcgaaaaacc
     9721 attgcgaagc gtcgctctga aatggaacag gtcaaacaga aaaaacagcc tgcttcttct
     9781 gttcatgaaa gaccgactac aagacaagaa caatatcatg atgaacagac ctcaaaacag
     9841 tctaatattc agacttcata taaggaatct caacaagcca aacaagatcg tccagcagtt
     9901 aagtccgatt tttcaagtcc aaaagtggaa cgccaaggca ataccgttca agaaaaaacc
     9961 gttcaaaagc cagcaacttc aaccactaca gcagatagaa cttcacaacg tccaatcaca
    10021 aaagaacgtc cgtctactgt tcaaagagta ccactacaaa atacaagaag tagaccacca
    10081 atcaaaaccg ccaccattaa gaaagtcggt aagaaaccat gaagttgaaa actttagtga
    10141 ttggtggttc tggattattc ttgatggtct tctcactgct tctgtttgtt gccattttat
    10201 tttcagatga acaggacagc ggaatttcca atattcatta tggaggtgtg aatgtttccg
    10261 cagaagtgct ggctcataag cctatggtag aaaaatatgc caaagaatat ggcgttgaag
    10321 aatatgtcaa catacttctt gcgattatac aggtggaatc gggcggtact gcggaagatg
    10381 ttatgcagtc ctcggaatcc ctcggtcttc cacctaattc attgagtaca gaagaatcca
    10441 ttaagcaagg tgtgaagtat ttcagtgaat tattagccag tagcgaaagg ctcagtgtag
    10501 atttagaatc ggttatccag tcctacaatt atggtggtgg tttcttaggg tatgtggcta
    10561 atcgtggaaa taaatatacc tttgaactgg ctcaaagttt ctcaaaagag tattcaggtg
    10621 gcgaaaaagt gtcttacccc aatcccatag ccatacctat caatgggggc tggcgataca
    10681 actatggcaa tatgttttat gtgcaactgg taacgcagta tcttgtcaca acagagtttg
    10741 atgatgatac ggtacaagcc atcatggacg aagcactgaa atatgagggc tggcgatacg
    10801 tttacggtgg agcttccccg actacttctt ttgattgtag cggactgaca caatggacgt
    10861 atggaaaagc tggaattaac ttaccacgaa ccgcacaaca gcaatatgat gtgacccagc
    10921 atatcccact atcggaagca caagctggcg atttggtttt ctttcattct acctataacg
    10981 ctggctctta tattactcat gttgggatat accttggcaa taaccgtatg tttcatgcag
    11041 gcgacccaat cggttatgcc gacttaacaa gcccctactg gcaacagcat ttagtgggag
    11101 caggacgaat caaacaatga gaaaggaaga tttaatgatg aaatttagaa aaaatcagaa
    11161 taaagaaaaa cagataccaa aggaaaagaa acctcgtgtc tactataagg tcaatcctca
    11221 taaaaaggtt gtgattgcct tgtgggtact tttagggctt agtttcagct ttgcgatatt
    11281 caagcacttt acagctatag atactcatac tattcacgaa acaactatca tagaaaagga
    11341 atacgttgat actcatcatg tagaaaattt tgtagagaac tttgcgaaag tctactattc
    11401 atgggagcaa tccgataagt ccattgataa tcgaatggaa agtctaaaag gctatctgac
    11461 agatgaactt caagctctca atgttgatac agtacgcaaa gatattcctg tatcgtcttc
    11521 tgtaagagga tttcagatat ggacggtaga gccaactggc gacaatgagt ttaatgtaac
    11581 ctacagtgta gaccagctca ttacagaggg agaaaataca aagaccgtcc actctgctta
    11641 tatagtgagt gtctatgtag atggttctgg aaatatggta ctggttaaga atccgaccat
    11701 taccaacata cctaagaaat caagttataa accaaaagcc attgaaagtg aggggacggt
    11761 tgattccatt acaaccaatg aaatcaatga gtttttaacg acgttcttca agctctatcc
    11821 tacagcgaca gccagtgaac tttcctacta tgtgaatgac gggatattaa agccaatcgg
    11881 aaaagagtac atctttcaag aactggtaaa tcctattcac aatcgtaagg ataatcaagt
    11941 cacggtatcg ctgacagtgg agtatatcga ccagcagacc aaagcaacgc aggtatctca
    12001 atttgatttg gtacttgaaa agaacgggag taattggaag attatagaat aacaaatatt
    12061 ggtacattat tacagctatt ttgtaatcac gtactctctt tgataaaaaa ttggagattc
    12121 ctttacaaat atgctcttat gtgctattat ttaagtatct atttaaaagg agttaataaa
    12181 tatgcggcaa ggtattctta aataaactgt caatttgata gtggaaacaa ataattggat
    12241 gtcctttttt aggagggctt agttttttgt acccagttta agaatacctt tatcatgtga
    12301 ttctaaagta tccggagaat atctgtatgc tttgtatgcc tatggttatg cataaaaatc
    12361 ccagtgataa gagtatttat cactgggatt tttatgccct tttgggcttt tgaatggagg
    12421 aaaatcacat gaaaattatt aatattggag ttttagctca tgttgatgcg ggaaaaacta
    12481 ccttaacaga aagcttatta tataacagtg gagcgattac agaattagga agcgtggaca
    12541 gaggtacaac gaaaacggat aatacgcttt tagaacgtca gagaggaatt acaattcaga
    12601 cggcgataac ctcttttcag tggaaaaata ctaagataaa catcatagac acgccaggac
    12661 atatggattt tttagcagaa gtatatcgtt cattatcagt attagatggg gcaattctac
    12721 tgatttctgc aaaagatggc gtacaagcac aaactcgtat attgtttcat gcacttagga
    12781 aaataggtat tcccacaatc ttttttatca ataagattga ccaaaatgga attgatttat
    12841 caacggttta tcaggatatt aaagagaaac tttctgcgga aattgtaatc aaacagaagg
    12901 tagaactgca tcctaatatg cgtgtaatga actttaccga atctgaacaa tgggatatgg
    12961 taatagaagg aaatgattac cttttggaga aatatacgtc tgggaaatta ttggaagcat
    13021 tagaactcga acaagaggaa agcataagat ttcataattg ttccctgttc cctgtttatc
    13081 acggaagtgc aaaaaacaat atagggattg ataaccttat agaagtgatt acgaataaat
    13141 tttattcatc aacacatcga ggtcagtctg aactttgcgg aaaagttttc aaaattgagt
    13201 attcggaaaa aagacagcgt cttgcatata tacgtcttta tagtggcgta ctgcatttgc
    13261 gagattcggt tagaatatcg gaaaaggaaa aaataaaaat tacagaaatg tatacttcaa
    13321 taaatggtga attatgtaaa atcgataagg cttattccgg ggaaattgtt attttgcaga
    13381 atgagttttt gaagttaaat agtgttcttg gagatacaaa gctattgcca cagagagaga
    13441 gaattgaaaa tcccctccct ctgctgcaaa cgactgttga accgagcaaa cctcaacaaa
    13501 gggaaatgtt acttgatgca cttttagaaa tctccgacag tgacccgctt ctgcgatatt
    13561 atgtggattc tgcgacacat gaaatcatac tttctttctt agggaaagta caaatggaag
    13621 tgacttgtgc tctgctgcaa gaaaagtatc atgtggagat agaaataaaa gagcctacag
    13681 tcatttatat ggaaagaccg ttaaaaaaag cagagtatac cattcacatc gaagttccac
    13741 cgaatccttt ctgggcttcc attggtctat ctgtagcacc gcttccatta gggagcggag
    13801 tacagtatga gagctcggtt tctcttggat acttaaatca atcgtttcaa aatgcagtta
    13861 tggaggggat acgctatggc tgtgaacaag gattgtatgg ttggaatgtg acggactgta
    13921 aaatctgttt taagtatggc ttatactata gccctgttag taccccagca gattttcgga
    13981 tgcttgctcc tattgtattg gaacaagtct taaaaaaagc tggaacagaa ttgttagagc
    14041 catatcttag ttttaaaatt tatgcgccac aggaatatct ttcacgagca tacaacgatg
    14101 ctcctaaata ttgtgcgaac atcgtagaca ctcaattgaa aaataatgag gtcattctta
    14161 gtggagaaat ccctgctcgg tgtattcaag aatatcgtag tgatttaact tcctttacaa
    14221 atggacgtag tgtttgttta acagagttaa aagggtacca tgttactacc ggtgaacctg
    14281 tttgccagcc ccgtcgtcca aatagtcgga tagataaagt acgatatatg ttcaataaaa
    14341 taacttagtg tattttatgt tgttatataa atatggtttc ttgttaaata agatgaaata
    14401 ttttttaata aagatttgaa ttaaagtgta aaggaggaga tagttattat aaactacaag
    14461 tggatattgt gtcctgtatg tggaaataaa acacgattaa agataaggga agatactgaa
    14521 ttaaaaaaat tccccctcta ttgtccgaaa tgcagacaag aaaatttaat tgaaataaag
    14581 cagttcaaag taactgtgat tacagagcca gacgcaaaga cgcagagccg ataaaatgag
    14641 attaatacaa tctcatttta tcggctcttt ccgttatgta tggattcttt taattagtct
    14701 tcgatgtttc ttgcttcgtt gataccgctg gctaaagatt ccattaagga tagttctttg
    14761 tctgtaaagc tatccatgta tttctctatc tgtaatcgtc gggtgctttt taccaagtta
    14821 ttagcaggta agaaaaattc atcaacggaa acatgaagta acgatacaag gtcataaaga
    14881 acttgtatgc tggggtgttg ccctttattt tcaatattag ttaagtaccg tgggtcaatt
    14941 tcaatcaatg ctcccacttg ttcacgagtt aaacttcgtt tcaatcgagc ttctttaatg
    15001 gctaaaccaa aggctctaaa atcatattta tcttcttttt tacgcatagt agaccacctc
    15061 tatacatttt attgttccta ctgaattaaa aacaggtata gaaaaacgtg ttatatggtt
    15121 tataggttta tatttaataa aaagcactac taaacgccaa taaaaaaaac cgttatatgg
    15181 tagtgctatt tacgctgtta aaatattgta tattacttcc aaatggcggt ttgttggagg
    15241 tcaacgtcgc catgaagtac atcatataca ataaatttcc ttacattggg ttcttgtcaa
    15301 aaaaagtcgt ctatctgcaa tagataagta cgtccaccaa tgtggtttta taaatcatat
    15361 agatagaata acagaagcat gtaaacagag aaataaatct gtttatatgc ttttttggct
    15421 attcagaact tttttacaaa gtttatttat cagtaatgca acaaatcccc ctttcacatt
    15481 gggactaaga gtgaaaggag ataaacgagc aaggctcact tcctttccta gacagaaagg
    15541 gggtgagaaa catgaaacca tcttcttttc agaccacaat agaaaatcag tttgactata
    15601 tctgtaaacg tgctatggaa gacgagcgaa agaattatat gctttatctt tcaaggattg
    15661 caaagcgtga ggtgtccttt tcggatgttg gcgattatct tgttagccag tttgcgacaa
    15721 cagataacta ttcaactgac tttcagattt ttacactcaa tgggttatca gtaggcgttg
    15781 aaaatgattt gttgagtgaa gcattacgtg agttgccaga caagaaacgt gaaattctac
    15841 tgctgtttta ctttatggac atgagcgatt cagaaattgc agacctgttg aaattgaacc
    15901 gttctactgt ctatcggcat agaaccagtg gactagcctt aattaaaaag tttatggagg
    15961 aatttgaaga atgaaaacac aatatcctat gattcccttt cctctcattg taaaggcaac
    16021 agatggcgat accgaagcga ttaaccagat tctacatcat tacagagggt acataacgaa
    16081 gcgttcccta cgacttatga aagatgaata tggcaatcaa agtatggtcg ttgatgaagt
    16141 cttacgtgga agaatggaaa ccagactgat tacaaagatt ttgtcatttg aaattaagta
    16201 atatcctctc tcctttcgtg gaagcgtgct aaaccattcc acgcttcccg aacagggagg
    16261 tttgttattc caccaaagca tattgagctt tcaatgtgtt ttgataggct aacgagccat
    16321 tgttctttga aaactgaata aaagtaatcg aatacgtttc gataagaaaa gagccaacgg
    16381 aactaaccgc catgacctat cttataaaga tagcgagcga ttcatgttag tgatccgaga
    16441 agcaatcttt agcaggattg cctgcaacga cattcttatc gtgataatga tactcccata
    16501 cagtcaatag tccgagcgtg ataaaaccgt cgcaggcaat gagtatggct acatgagaac
    16561 catgcagggg tggaactccc gtgagctttg ctaaagctgt tcgattgctg gtaaaacaac
    16621 ttttatgaaa tccaaataag tgatttggaa aggaggattt tatgaagcag actgacattc
    16681 ctatttggga acgttatacc ctaaccattg aagaagcgtc aaaatatttt cgtattggcg
    16741 aaaacaagct acgacgcttg gcagaggaaa ataaaaatgc aaattggctg attatgaatg
    16801 gcaatcgtat tcagattaaa cgaaaacaat ttgaaaaaat tatagataca ttggacgcaa
    16861 tctagcgtcg ccaaagggtc ttgtatatga taaaatagta ttaagtcgta tcaaggctct
    16921 ttccataaag gaaaggagca aatgccatgt cagaaaaaag acgtgacaat aaaggtcgaa
    16981 tcttaaagac tggagagagc caacgaaaag acggaagata cttatacaaa tatatagatt
    17041 catttggaga accgcaattt gtttactcgt ggaaacttgt ggctacagac cgagtaccag
    17101 caggaaagcg tgattgtatc tcacttagag agaaaatcgc agagttacag aaagacattc
    17161 atgatggtat tgatgttgta ggaaagaaaa tgacactctg ccagctttac gcaaaacaga
    17221 acgctcaaag accaaaggtt agaaaaaaca ctgaaactgg acgcaaatat cttatggata
    17281 ttttgaagaa agacaagtta ggtgtaagaa gtattgacag tattaagcca tcagacgcta
    17341 aagaatgggc tattagaatg agtgaaaatg gttatgctta tcaaaccatc aataactaca
    17401 aacgttcttt aaaggcttca ttctatattg ctatacaaga tgattgtgtt cggaagaatc
    17461 catttgactt tcaactgaaa gcagttcttg atgatgatac tgtccctaag accgtactaa
    17521 cagaagaaca ggaagaaaaa ctgttagcct ttgcaaaagc tgataaaacc tacagcaaaa
    17581 attatgatga aattctgata ctcttaaaaa caggtcttcg tatttcagag tttggtggtt
    17641 tgacacttcc agatttagat tttgagaatc gtcttgtcaa tatagaccat cagctattga
    17701 gagatactga aattgggtac tacattgaaa caccaaagac caaaagtggc gaacgtcaag
    17761 ttcctatggt tgaagaagcc tatcaagcat ttaagcgagt gttagcgaat cgaaagaatg
    17821 ataagcgtgt tgagattgat ggatatagtg atttcctctt tcttaataga aagaactatc
    17881 caaaagtggc aagtgattac aacggcatga tgaaaggtct tgttaagaaa tacaataagt
    17941 ataacgagga taaattgcca cacatcactc cacatagttt gcgacataca ttctgtacca
    18001 actatgcaaa tgcaggaatg aatccaaagg cattacagta cattatggga catgctaata
    18061 tagccatgac gctgaactat tacgcacatg caacattcga ttctgcaatg gcagaaatga
    18121 aacgcttgaa taaagagaag caacaggagc gtcttgttgc ttagtagtac aaatgaattt
    18181 actacttatt taccacttct gacagctaag acatgaggaa atatgcaaag aaacgtgaag
    18241 tatcttccta cagtaaaaat actcgaaagc acatagaata aggctttacg agcatttaag
    18301 aaaatataaa aagataatta gaaatttata ctttgttttt attaaaaagc agcaaactat
    18361 aaactagtag gttccacact aaatgtagcc ccatactgcc ccacaagtcc gatttatagc
    18421 gtaccatccc taaaaacatt cccaatgaaa catataaaca ccaagctaga atggttcctg
    18481 gatgatgagc taaggcaaat aaaacacttg tcaaagcaac tcgaatatct aattttctaa
    18541 ccaagttcca taaaatttct ctatacaaaa attcttcaac catactcgca ttgattaaga
    18601 acaataaaaa tgaaaaccaa ggaacttgat gttgaagccc aattaagttt gcttgatttg
    18661 tgctttcttg agcatgaatc agactaaaat atagactgat aatcagtagg ctaacgaatc
    18721 caataccaat ccactttatc ctagtttcca tattgacctt ggccacttgt tttcgttgac
    18781 catacatcca taaaaaagaa atgagcgacg ctccatagat aatctgtagt atagttaact
    18841 caccgataca aagaaatttc agtaagtata aggataccaa taggacattt acttgttgga
    18901 atatataaac tggaattatt cttttcatag ttacctccga aataaatctt cataatctaa
    18961 atctaatacc tgcacaatcc tctctaccca tggactttga ggcattcgtt gttccatctt
    19021 gtagtgacga atcttttgat acaaacgatt caattcactt ggatagtgaa actctcccgc
    19081 aaacattttt ctggttaact caatccagct gatatttctt tcagccaaaa taatggacaa
    19141 gttctcccaa aatcgttcag ccatattgct tctcctttag ttagataaat aatgtgtttg
    19201 tgccatgtaa atcaattgtt tcgtatctct tggtaataaa gccctagctt cctccaaatt
    19261 tagatttgga taaactcgct tatttgaaac cgcaagagga agtctgatgg ttagttcagg
    19321 attttttaat atcatttcaa tgaaatccgt tagtcttaaa ttgtcacggt tcttaaatcg
    19381 taataaatta ggagataaaa actcaaaaca atctgaagaa tagctcatca tctcaattaa
    19441 tttatccctt gtcatttcag aaatcgaatg acaggatacc tcaatgccat agttttggaa
    19501 gaattctaaa agaagttgat ttctatggtt atttttactt agatagagat caatcatgtg
    19561 agacctccca aagattcggt tccatttgat attctgagac gattaaggaa tctaataaat
    19621 tggagaagtt aattgatttc ttgtcttcat cataagcttt tacagttact tgggttgtaa
    19681 gtattccctc ttttccctcg gctcgatagc cttgcccata taaaacaaaa acaagattat
    19741 gattatcatc tataaaggca tcagctccgt tctttatatc ctgactttca aggaattcca
    19801 taatgttttg aagataggat tcgtaaaata gggggtaatt gtgtttttta tggtaataat
    19861 ctaaaaatgt cacctcaaac tcacatggat aattgggcat caaaaatatt tgttcatcca
    19921 actgcatcat ttctgcatca tgtaattctg tttctaattc atcacaatat agtattgact
    19981 ctttatttag cgctttcatc tttttcctct atttctttta atttttttgc gattgcggca
    20041 atcacaggaa cagttacact attaccagct tgtttataga gctgactatt actagagact
    20101 tttctagcag cttcaaaagc ccaatcagga aagccctgca gtcgaaaaca ctctttagga
    20161 gtgattcgtc gtattctcaa acggtaaaat tgtccatcta ttaaaacacc agctacttgg
    20221 taaacttgtt tatcttctcc ttcatagcta gccactacta ctcccatttg accactagtt
    20281 gttaatgtat tcgctatacc ttttccaact ctaccacgac gatactgaga acttggtctt
    20341 tctaaattga ttgaatctcc aatctctgct tgagcatacc cttttttagt tgcttcccgg
    20401 acttttagaa attggattgg ttctggaatc agtattttgg gaattttatc tcctccttgc
    20461 atcgtagtca gtgttggaga taagccctcg cttccataga ctcgacctgt ctccttaaag
    20521 ctagtcggta aatctccaac aacgacaata ccatgacgat cctgagtatt taaagtaaac
    20581 atcggctctt ggttttcctt aaagcgtctc ccattttgtc tcttgtctaa tctgtctggt
    20641 gtcatacaag gaatcgcaac cttgaatcct tctccttttc cacgaactaa ggttggtgca
    20701 agaccttctg aataatagac tttaccgctc attccacttt ttgatggatt caaattccct
    20761 agtgttttta aagtctcaga gttagttgtt tgaccttctc gtctgaaagg aaataagagt
    20821 ctggtacctc tctttctaga atgtccgata ataaacaccc tctctctgtt ttggggaacg
    20881 ccaaaatcct tactgttaag caactgccac tcaacatcaa accccaactc atcaagtgtg
    20941 gtaaggattg tggtgaacgt ccgtccctta tcgtgattga gtaggccttt aacattttca
    21001 agaaaaagaa aacgtggttg gatttgtttg gccgcccgag caatttcaaa gaacaaagtt
    21061 cctctagtat cttcaaatcc caatcgtctt cctgcgattg aaaatgcttg acaagggaat
    21121 cccccacaga tgatatcgac tttccctcta agttttttaa attctgcatc tgaaacatct
    21181 cgtatgtcat gaaattctat ttctccttcc gtttgaaaaa tggacttata agatttccta
    21241 gcaaatttat caatctcaca aaatccaata cactcgtgtc caacactttc cattccaagt
    21301 cgaaatccac ctatacctga aaataaatca ataaatctca tttcttgatc acctctttct
    21361 tatcgactac cattgtcata actgtcactc cacttgaaat gacaataagc ataactaata
    21421 tccactcgat tgacgacatt taaccacctc cttttctaac acggttattc caaacagaat
    21481 acaggccatt aaacacaaat tcagcaagta cttccgctcg tctaacaaag cgaacattgt
    21541 caagagcata ctgatagatt ctttcaaaat cagtcatagc aatttcactg gctgtttcag
    21601 aaaaaccttc tcgtctaaat tgatcttgta ccaatcccca aatataatct cgatcatatt
    21661 ttgtgacctt ttctactttt cttttcaaaa taggttgagt attcctatcc tcctcatcct
    21721 caataaataa agaatcagtc tcactatatt tagtctcact aacttcagtc tctctagggg
    21781 ctgaatgtga gactggggcc gtttcatttt caacctgccc tagtcttttt ttaacactag
    21841 gcctgtttga attacctact ggggtagaag ataattcccc taaataaatc ttattagcta
    21901 gtcttccttt ctcacttgaa gactgttgaa cttcatcaat taagtcatat tctttaagaa
    21961 tttttttgat agacagtaat tttgacttcg agcaacctaa cagcttcatc agtttagaat
    22021 tagaaaatac taaataaacc gctccttctt catctatcca accacgactg agagataatt
    22081 ctaaacgatc ttttaaaata gaataagcca cctttacttc tagtttcata tccatatatt
    22141 tctcatcctc aaaaagaatt ttaggtaatt tgtaataccg ttctgaagtt tggtattgat
    22201 ttgcggtaat tcgtttcata gcgcacctcc aagttctttg agtgttaaat ctccgcttga
    22261 ttccaattga accaagccac ttttttccaa ttcagccata agagagatgg cttcaacaat
    22321 gtcaattccc atttcacgta ctaaaaatga aatgacaata tagcgtgatg attgtaattc
    22381 ttttgtcatt ttccctcctg aaaataaaaa aaacggaaag attgtgaaat tcctttccgt
    22441 aacataataa atatttgaac accaaactca acaccaaaaa aatgttttta ttgataatta
    22501 ttgctcaatc aagcacttat aacaatgtaa aaaataaaaa tctgtactca caaaaaccct
    22561 tgaaattcaa gggttttaag catttattct acttcacaat gttttattat tttaaatctt
    22621 ctagaccaac cattgaatag tagccattga gttttttcct ttcgtagcaa ggatttagat
    22681 cccctatttt attttactat agtttgaaca tagagagttt tcaaatgaat gatgtccaaa
    22741 cagttcttgt tttatgacat agaaatctac tttatattat atcatgcctt ctttattttg
    22801 tccgatgata gccttttacc ctatctttta gcctatcttt taccctatat agaaaaaagc
    22861 catcaaatga tgacttttca gagggagcaa aaaactgttc cttctatatt ctaaacattt
    22921 aaatgtcttc tttaaacagt ttattaaaga aaccgtctgt gtttttaaga agggctttga
    22981 agaccttaga tttaagagca acagtgtgag agaagtcatc tggtttcttc aaatcttctt
    23041 caactgcttt atcaaataaa ggccttaact catcatagtt actgatatgg acgccatcaa
    23101 tatcgatagc ctcaaaacct ttcttagctt tagcaagaac ttccccgtac caatgtctct
    23161 tccactcttc aagagtatta aagtttcctt tcgatacttt attaattatt agcttatcgc
    23221 ttagtaaacc gtggttgttt ttatctgctt ctgctttgta tttatttgat acataactaa
    23281 taaagccatt ttcataacca taatagcccc acatacggaa agcattgtgc ttaaatgata
    23341 atgaaccagg agcaccttga ctcgtattcc caccgtaaat tcctgccatc atattgacat
    23401 ttacgtaagc tgagtttggt gtaaaatctt ctggtctata acgtccatta cctggatttc
    23461 catgttttgt catgaagtta ttatccacta aatcattgac gctagataaa gtcattacct
    23521 tttcttcatc tttcaaatca cggatactat cccattggtt tggacctaaa agatcattat
    23581 actgaatctt agagcgcatt tctttgtcaa tcttcttgaa ccacttacta ttgtctcctt
    23641 taattttagg aagtacagca tcagcttcta catgatcaag caacatcata gcttcattgt
    23701 agtttctcat gtagcggtca atgtcatcac gtgtctttaa tttgtcagga tctgggttgt
    23761 accattggtt accatcattt ggacgatggt aagccatgtt aattccaagt gcgccgtatt
    23821 caccattagt cgttgagctg tcaggtgttt gcaacatacc ttgagcatag gcttcaacgt
    23881 ctgtaccttg acgatgctta tgaccaccga agtaaagcat tctatcgttt acgtgtgttg
    23941 tttcgtgagt aaaggctgaa ataccaaatg ggctaatcat atccgtcacc ataaacaaga
    24001 ccttgtcatc attatttgga ttagggaata ttgatgccat agcgcccata cgccagtctc
    24061 tatcatggtg tcgccatgtt ggaccatata attcacgaat tggagctata gggttacctt
    24121 tactgtcaaa tcctcgacga cctacaggag aaccattgta ggtctggtta tcccaaactg
    24181 gtgtcggtac catattttga ctcttaagaa gtctatcacg aacattaggc agagctaatc
    24241 tggaccagaa atctaaataa gtttgttgag catgtgcaac ttcatcaatc ttagttttga
    24301 actcattacg agcttcttct gtatgttttc catatttctc aaatgaactg tacgccatcg
    24361 tgttatatgt tgaaattaag aacatatggg catctttaag cgttagaagt ggtaaaatca
    24421 tacgaccatg aacaccgtta tctaaaccat cgaacacacg atgacgttta tctttcaact
    24481 ctgtatttgt tgtcttaggt tctgaaacat aaacattctt agctgagtgg ataaaccaat
    24541 cattgatgtc tttatcctct gtaaacagac gcatgttgta ttctaagaag ttacgcaaat
    24601 tacttttacc agtattacct gcgatgattt cacggtaagc atcctgagtc cgatcccctt
    24661 tcaagttctt ttcacttgaa ccgatgttga tgagtctgtc aataacactt ggtgttttac
    24721 cataaaaatc aggtttgaac atcatgatgt tttttatact tatgtcaccg tatttgatat
    24781 catagtaacg attgagataa gtcagagcca tcatgatttt agctttattg gtttccactt
    24841 tcttgagaag tgattttatc gcagcttcat caccattcaa ttgatggtct tcattttcga
    24901 ccaaggattt gactaactta tctagatttt gcttcacttc ggcaaagctt tcttctaagt
    24961 atagatcttt aatataacca ttcttacgtt catccgtatt ctctgcaggt ttatcacgtc
    25021 tactcattaa atctcttact tcttgtgaaa tcaattccac acttgataat tgagatttaa
    25081 catcagcaat caatttatca cgatttttaa caaccatatt cggtgtataa acaacatcac
    25141 caagaccaga tacactatat tcacgcactt gttggacttt agaatcagta ttcttagtaa
    25201 catccatttc ttccttagta ccatcagcat agtgaaccat aatcttatca atatctgata
    25261 aatcggtcac gaattgacca tccttcatcc ccgtaacaga aaggacttct ttcttagcta
    25321 agtttgaatc ttctgcaagt ttgttacctt ggttgacaat ccattcttta ttataaaatg
    25381 gttgaagttt ctcaatatta cgataagcta aatcacgttc ggatttgtag tcttgagttg
    25441 acttatattc atcttctctt ctggttaaac gatttaagcg attgaccaca ggttcgttga
    25501 tttcgtattt atcagcagta agtccaaaat ttgcaattct cttattagct tcatcttgac
    25561 taatttcttt aattttgtca cgagaacgtt tgtatgaatg cttacctgaa ctgacacctt
    25621 tgacaacaaa gttacgctct aaccagccat ttgtgaaata accaccatcg tagtccaaat
    25681 cggaagaacc aaagaactct tcaccatttt caactctcat cattgaaata ttatcttcaa
    25741 gtttaccaaa aggaagattg ctattgataa atccacctgt ttcaaacaaa actttagtct
    25801 taatggttcc tttggtgact gatttacgaa ttgaaccgta tttaccaatt cccatagagt
    25861 cgttaccatt atctgtttta gcaactaaac cacctatacg ggctctgtta gcaacaatat
    25921 cagcctcgac atatgctttt gcaagattac ctctccaaat ctcaccggca atgccagcca
    25981 tatattgacc tttatcacca acacctgtaa gattaccgat gaaggctaca tttgtcaact
    26041 gaccaccact atcgatttta ttgacgatac ccgcaatatt gttattagca actacattac
    26101 cagttacctt aacatcttca acagttgcat ttttcaccat attggcaaca ggtgctattc
    26161 cgtcagccca aggcatattg atatccacat tacctaaatt aatatttttc acagaaccat
    26221 tttcaacacg gtcaaataag ggacgggcaa tgttatgaat tgtatattgt ttaccatcaa
    26281 cacttgatag atgtccctta aacgtacctg gaacatattg tttgttaggt gttggtacat
    26341 tcgttgcatt caaatctgct ccgattttaa atgtaccatt tttatcagca ttcatggcat
    26401 ctactaactc tttaaagtta taataaacgt catcaacttt tggaactggt ttttcaatat
    26461 aatgaacata cttgttacga accttcgttg ggtctgtatg ttgaatcaaa tcttgagctt
    26521 cggcagtgat tttataaagt ttcttacctt cttcagtcac ttcttcaatt ttatcaactg
    26581 ctaaacgtgt tactttatta tcacgactag taatttttaa gtacattttc ttcacatctt
    26641 catctgaagg tttttcagtc ataaaatcac taggtgtttc agtaccatcg tcatttacct
    26701 tcactaaatt agtagatgcg atatttttaa tttcaacttt tttcaaatcc aagcgaagtg
    26761 gtttctcttc taatgttgca gtttcttctc ccttgccacg gtcataggtc atagtggtct
    26821 ctatcttata gtccttgtag aattttaaat cttctacctg cttatctaat tgctctgaag
    26881 tcaaatctac tgttttgaca atttcatttc catctttaat tgtcgcagta attttattga
    26941 ttgtgactcc atctgtatta actaaatgat aagaaagagt tgcggatcgg tttaatacat
    27001 ttgtatttgt tctatctaag gtcaaaacag gagccgtttt ttctttaggt ttttctttgg
    27061 taccttttac aagaatttta ggcttcattt ctttcaaaat agttactgtt tcaactgggt
    27121 cactgatttt tttgccatgt aactcttcat agctagtaac aatttgacgt tcgccatcct
    27181 caccaacttg tctaacagaa tcatcgccta taaatttgct aggatcagat tcttctatag
    27241 tggttttagg aatagtctct gtccgaatat cggtatgtaa agaaggcaac tcttctcttt
    27301 ctgatgcaac ttctgaaact gtagatattg gttcagtata ctctggaatg tcgctaacag
    27361 gtggctcaat caagtttcca ttttcatcca ctcctgttgt acctactggc tcagtatatt
    27421 ctgggatgtc gttaacaggt ggttcaatca agtttccatt ttcatctact cctgttgtcc
    27481 ctactggttc agtgtatgct agtttctcat gaacttcagg ctcaacaagg tttgcaccta
    27541 ttggttgcgt atagtcaggc ttctcatgaa cttccggttc gcctttctct gttacaactt
    27601 tgggttgctc aactggcgaa acagttgatg ctggagaaac cgacgaaaca gttttatcat
    27661 caagctccaa gtaaccaaca tatctgtaac cagaaatttg caacacacca tcacgtccag
    27721 actcatggat gttagcattc aaattaagtg ctgaagcagt tgatagtgta actaaacctg
    27781 tcgcccctac aatcaaaaat gtagctattt ttttatttct attatctttt gtgataatca
    27841 caataagact cccgatagct aacaaaccca atgcagtcat aatagattga gaacttcctg
    27901 tgtttggtag tgcgtctttt tcataatcca aagcatatga ctctttggat tcatcaggtc
    27961 taccttgttt gagttgatca cgttcagttt gtgtcaaact actataatct aagtaatgat
    28021 aagtcgatgc accaacaact gacggtgcaa ataaaagact ccccaagaat accgaaccaa
    28081 caataccctt tattttccga atggaaaatt tatctttttt taataatgac aattctaatc
    28141 ctccaccttc actttttatt tcctaatagt aaacactatt ttttattctc aaaaattgaa
    28201 cttctaaaat caccggtttg gtcaagataa gctttaaaga ttgctttttt cagtttaaga
    28261 actctactat ttgtctcagg atataatttg gcaacttcat cctcagcatc aaattttact
    28321 gcatcttcaa tcattttttc aagtctatta atattatcaa tagtcacttt ctgttgtcga
    28381 gcccaagaac cgtttggatc gataaaacta actttattta actttccaaa tttatcttct
    28441 ctttctttat acatatcttt cttgaaatct atccaagaat tatactggtt attaaatact
    28501 tttgaaagaa caatttcatc agtaactaaa cctatttgtt taccatatga tgtaataact
    28561 tttccttgag ctttcgcttc tttttcatac tgattagaaa tatatggaac cataccgtct
    28621 ttgtacccct tggctgccaa taactcaaat gcaatacgtc gtcccattaa atctcctggt
    28681 gttcctattt tactgctcaa tgctgaataa attggtgaga atagattaat tgtatagtag
    28741 ccattccgct tataagttgc ttcatctaca taacctcttc ttgttataat atcatgttct
    28801 atcaaactgt taaatgtagt taatttagta agttcttctg gttttaatct acgtacaaca
    28861 ttcgttgcat aaacagaatt tccatcagga tcaggtttat attcattttc tatttttctt
    28921 aataaatcat atttttgatt tgtatctaat ttagctacag ctttaccttc tagtatttca
    28981 agcatgtata ttacatcaaa catattatgc atatacttat ttagatcatc aacacttcca
    29041 aatcgttgag ttggatctgc tacttgaagc cttgttgatt cttctgattg atcatatttt
    29101 aatatggaat taatagtgac tgttggatca ttaggatgat caggagcttg tagcagtcct
    29161 ttagcataaa actctggtcc aagtccattt cgtcttccat agcctccaag ataaatttct
    29221 ctatctgagt tatgtgtcat ttcgtgtgta taagttaccg caccatcttt atcaagcatg
    29281 cgatatgcca tataatagaa tgcatcccct gtagcatatg ctccattaga attatgaaca
    29341 acattatttc ccgctggacc gaagaaatgt tttatagctg gatgattagt ttcaaaagtt
    29401 gcttgatatg tatctttatc ttctttttca tctgtaccaa atctaaatgc atcatagact
    29461 agaacacttc tatataattt ttctttattt ttatcatcta gtattctata ccaataatca
    29521 tagtgatctc taaatctaac agccgcttct ttagcttttt tctcaacata gtcatttaaa
    29581 tcagttcctg ctggatgttc tttacttcta tatctatcat aagcaccgaa acctatagtc
    29641 gaaatgttgg ctataataaa caccgatttt tcaggtaatg ttaatagcgg caacaccata
    29701 cttggatatt tccaagatgg gctagttaat ctatcatata ctccaattga atatggacta
    29761 ccagctattg attgcttatc acttacctct ttaatagtag atttttcttc tacaatatat
    29821 gctttagttt gttctttaaa ccactcatta tttgttttat ctggtacaaa tgcttttcta
    29881 tatttctcta atgcatcaaa taaattatta gtcttataat ttttcgctaa taaaacatta
    29941 taagttataa cattattttt tgctagtaag ttattatatc ccgatttacc tagttcgata
    30001 acattatcta acgctgaact atttgattta ccgaagaaat ccaagtggta catgactaaa
    30061 tctttcgctt ttgtatcacg atatttgaag tcgtaccaac gctctaagta tgttaatcct
    30121 agaagtaaag cttctttatt atttttaatt ttctcgatta cataattatc tattacctta
    30181 ttgttatttt cagctattgc agcatctgca gtaagaagtt ttgtcaaact atctttcaaa
    30241 ttagtttttg tggtattgaa ttgttcttct aaatataact ccgttaaact aacatcctta
    30301 gaaacatcta atacttttct aattgcctct gatttatatt ctacactatt taatgctggt
    30361 aatacttcat ctaaaatatt ttgataattg cgaagtaatg tattcggtgt ataaattaag
    30421 tttgtaccgc ctattctata ctctgctaca tttgaaaaat cagtttgata atttacatta
    30481 agtgtctctg atgtattatc cgcgtaatat agtaatagtt tatttatact tgatttattt
    30541 ttgttaatat cactaattac ttctttatct ttcataggga ctactgacaa taattcttta
    30601 ttataaagat tactacttgt ctctactaaa tttccgtact taacaattgt ttctctatta
    30661 taaaacggta atagtttttc aatattttta tatacttttt cttttgatga atcagcattc
    30721 tcaagatttt tatagtcagt tacatatcta gaagagaaat taaaatcttc tgttttaata
    30781 gtatttttag atacaaaagt agcttttttc tcttttattt gtgcatcttc taatacttct
    30841 cctctttgaa cagtagaatc cttagttaag atttcatcat cttcttgtac tacgttcaca
    30901 accttattat ttttattact gtatgtgcca tttgctttta taccattaaa attataacct
    30961 gcaatagcat taccattcgt tacattaaca tcgcttagta cattagaaag tcgaccggat
    31021 ttttctaatc ctccaaccgg atcccaaaga ttaccaacta ctccaccaac gtttgcaaaa
    31081 cgttgaacat tatttagatt tccttcagca taactattac taataagcgc actattttct
    31141 actgcaccaa ctattccacc aatagactgg tctccttgtg ttgcatttga agataaatcg
    31201 attgatgcga acgacttatc tattaatccc ctcggaccag aaagtttgcc tactaaacct
    31261 ccgatttgat aactagcaac tgttttatat gtattagtta ttctacctgt atagctactg
    31321 ttagaaatag tagaattatt aacttgtgat actaatcctc ctatgctacg ttccccagct
    31381 atcgctccat cagcatgaac gttatcaata tgagtattgt tatttgcttc tttcgcaagt
    31441 gttgcagtat cgtcctttgc ggaaatatta acatctttta gtgaaagttt ttctactgta
    31501 gcaccattta attccccaaa taatggtttt ttcaaattat aaatagcata atatttctca
    31561 ttatttgttc ctactaatat tccatggaat acattattca cataactttc ttgaccatct
    31621 ggaagttcaa cttcacgagc atccatagtt gctcctaaac ggaatgtgcc attaggattg
    31681 ctattcattg catctactaa atttttaaat gatgtatata ccccagtttc actttgctga
    31741 gtttttggta aatagtatgt ataattttct agtacattat tattttcatg ttgtatcaga
    31801 ctatttgcac ttgctactat cttataaaca tctctattat ctttagtatc attagtaatg
    31861 cttgtaactg gtagcatcac atctttaaag ttctctgatt taactttcat aaagtaattt
    31921 tctgcattac ttggtaaaga agcaagtgaa gttacatgtc gatacttatt accatctttt
    31981 gaatatagtt ctacagaaga tatatttcta agttctaatt tcttaataac ttctttttca
    32041 tctttagcgt catctttttt ctcatcttta tgacgataaa gttcatcgta tactggtgga
    32101 atttcattac ctgctataat actcttaatc caagctaatt gtgtaggaga taaaatcaat
    32161 ccgcctgagc gattttgtgc tccattttga tgcacaccaa taacttcacc attagcatta
    32221 aatattcctc caccactcat accaggattt ccaccttgat attgaacacc gtaggtgtta
    32281 ttcgcatatt cttgttccat ttctaccgta gcatctttta agtgcgtata tttcccagct
    32341 ggatatccat gaacatttag tttgtcatta agatttactt tcgaataatt tttaactaat
    32401 tctacatgtt ctctgccagt tgtttcaggt agcttaatca ctgctaaatc atagataaat
    32461 ccttttggat aatctttttt attataaaaa tgaatattgt tagcagtaaa tgttcctttt
    32521 tgtccatcag gagtcaccca ctcatatacg tttttagatt tatcacctct aaattcgcca
    32581 gtagtattat cagtagaatt attaatgaaa ttatgtgcta ctgttaaaag tacatttggt
    32641 gcaataaaag tagctgatcc tactccagta accttcgacg aatctgtaat aaagttcata
    32701 ttaattaatg cactagattt tttctgaata ctcatttctt ctggtgtatt agtattttca
    32761 ttatttggtt tagtatcttc tgcactaggt tgttcgattt taccagtata ttctttcagt
    32821 gcttctactt tttctggttc tactattgct ccggcttgca cccctgtgta ttctggtagt
    32881 ggtgctatct gctctggttc aacaatagcg ccagcctgca cccctgtgta ttcttttgat
    32941 ggttctactt tttctggttc tactattgct ccggcttgca ctcctgtgta ttccttcggt
    33001 gcttctacct tctctggttc gactatcgct ccagcctgca ctcctgtgta ttccttcggt
    33061 gcttctactt tctctggctc gactatcgct ccggcttgca cccctgtgta ttctggtagt
    33121 ggtgctacct gctctggttc aacaatagcg ccagcttgta ctccagcata ttccggttca
    33181 actttttcag gttcaacaat agctccagct tgtactcctg tatattctgg tagcggttct
    33241 acctgctctg gatcaccctt gtcagtcatg actgcctctg gtaacgctgg ttgaacttct
    33301 ggtacgcctt tatcacttac tacagcttct ggcaactctg gttggactgc tgactcacct
    33361 ttgtcggtta atacagctgc tggtagttca ggctgaattg cgggttcaac aatagctcca
    33421 gactgtactt ccttatgttc tgcaccagtc tcagcttgtt cctttataac ttgagctttt
    33481 ttagtacctt tttcgactat tcttgaaaca ggcgcagtcg ttgaagttga aataatttct
    33541 cgtgaaactt cttcattgtt tacagaaaat attctgacga tttcaacttt cttacctaat
    33601 gcaccttctt gttttactct tacagttcct tctgctaaat caggattttc ttgaatttct
    33661 tcttgaaaat ctatttttgt ttctatagtt tcgtcacgat ataagagttc cggtttgttc
    33721 aactgacctg atagcacttc atcctgtgga tttaatgtat ttaccccagt cttttccttt
    33781 ggagaaatct tctcctcttt cttcgtttct agattcttat gttcggctaa ttgttcttga
    33841 gaatctgaag attgtttctc ttcttttctt ggattgatta attcagtaga gaaaggtttt
    33901 tcaactactt gaacttctgt cggcttagtt gaagaaacag gtgtttgttc ctgaatagct
    33961 tgtactgttg atggatggtc tacaaaattt ggtgtaacat tataatccac cttttgttgt
    34021 tttgtaggag tggctgctga tttttcttga ttacttactt caaaatcaga agtcgttttt
    34081 ccctctttga tatatccaat ataagtgtaa cctgaaatct ctttaggaag aggtaatttt
    34141 tctccagagg tcaattcata gtccgtattg taatttagca aaagatgatt ttctaaagca
    34201 tggactgaaa ctaagacacc atttcccatt cccgcaacca atactaaatg taataccgtt
    34261 ttattcttaa cctttttctt ggaaacagca aaaattaaaa ttcccagagc agctaagcta
    34321 gcaccagcaa ctagggcttg cctctcattc ttgcttccag tatttggtaa ttccgccagt
    34381 tgattttgag aatttaactt ataaacaaga taataagttt catcatcatt ctccacgtat
    34441 gtcggaatat catagacaag ctgcttcttt tcttctgatg atagctctga atctgccaca
    34501 tatttatagt gaactcccgc agtttcttga gcatccacag atgaactagc taatacagac
    34561 ataaaaaata aacttgaaat cgttgcagat acaagtccta ctgataattt tctaaatgaa
    34621 aaacgctctt gtttttcacc aaaatacttt tccattattc ctccttgaaa taaaatttat
    34681 atatgttaca aagaccttta ttatattagt gtattatcta ttatctatag aaaaggcagt
    34741 ataccttaat tatactctta atttacaaaa aagtcttaaa attgagatgc gctttcatac
    34801 tttgttttat attatttggg ggtacaataa cacctaccat gaaatttaca cggtaggtgt
    34861 tactcatatc actaatcgtt ctaaaaatgg tttgaggcag ttgaggagaa ttccttctat
    34921 ccagcttcct tgtgctgatg agcgatggtc ttcctgcagg ctttttttta gaaaatctcg
    34981 gacttgttct ggtgcgattt caaattcaaa ggctttcatt ttatagaaaa agtcgatgag
    35041 atgatcggac aggtattcag ttgaaaaggg tacttcacca ctttttcgat attctaataa
    35101 gagcctagaa aatcgagctt tttcttcagg aagctcacga aaataggaat tgaggagcca
    35161 agtctgcttc tgttttcttt caattggatc ctgactggca attcgttggt ctttttccag
    35221 ctctttttgg tattgtttgg ccttgatagc ccgttctgct ctatttttac caaaaagaat
    35281 tttttcccac ttgcgttctt cttgagtcag ggtctctgta aagccaaagt aatcttgata
    35341 agcacgctct gcgggtccca tggctagaac cagattgtct gcatattgct tggcgatttt
    35401 atccctcttc ttgcgttctt tctctgcctg gatacggagt tcttgttcgt agtcaatttt
    35461 ctccttgcct agcttgacaa ggtagagttg gtcatccgat ttcccaagta aaaagggttt
    35521 gatacacttt tcaaggactt cttccatccg agcctttttc tttggttccg ccttggtcca
    35581 acttcctccc tgaaagactt ctaggaaaag ctggtagtct ctctcaggcg caaattgatt
    35641 gccacgattg ggtttgaaaa cacctttttc ccagagccat tttagaagtc gctcgtcaaa
    35701 gtcactttta ttgaccttga ttttttcttt tttctgagct tttctggtta gattttcaac
    35761 ctttctgagc agtttttctt cctcttccaa ttgctggtca agggacaatc gatgaaaatg
    35821 acgaacacag tcgctaccaa ttggaaagag gcgttggcct gtgacaccgt taaagagttc
    35881 ataagcgtat ttgatggcat ttccacagac acaattgcta cggccgatac cgttaaaaat
    35941 caaggaaact tcattccatt ccttggtagc ttgttcccaa gtatccgctt tcgaagcctg
    36001 taaaactgca tcgtgcaggg attttctaac tggaagtgtc atgaggtctc ctttctaata
    36061 ctcaataaaa atcaaagagc aaactagaaa gctagccgca
//
LOCUS       DAVBOD010000017        34124 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 640-05
            SAMEA1012484-rid20186543.denovo.017, whole genome shotgun sequence.
ACCESSION   DAVBOD010000017 DAVBOD010000000
VERSION     DAVBOD010000017.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012484
            Sequence Read Archive: ERR059358
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 34124)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34124)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979948.1
            Genome Coverage       :: 595x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:03:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,266
            CDSs (total)                      :: 2,219
            Genes (coding)                    :: 2,091
            CDSs (with protein)               :: 2,091
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 71 of 128
            Pseudo Genes (incomplete)         :: 50 of 128
            Pseudo Genes (internal stop)      :: 33 of 128
            Pseudo Genes (multiple problems)  :: 22 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34124
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012484-rid20186543.denovo.017"
                     /strain="NIG 640-05"
                     /db_xref="taxon:1313"
     gene            complement(21..833)
                     /locus_tag="VQ862_000907"
     CDS             complement(21..833)
                     /locus_tag="VQ862_000907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000162344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HET3115274.1"
                     /translation="MTKKIIAVDLDGTLLNSDSQISDFTKKTIKKVAEKGHQVIITTG
                     RPYRMSKDFYRELGLDTPMINFNGSLTHLPDQVWDFEKCLTVDKKYLLDMVQRSEDIQ
                     ADFIAGEYRKKFYITNPNEEIANPKLFGVEAFQPEDQFQPELVTKDPNCILLQTRASD
                     KYALAKDMNAFYQHQLSINTWGGPLNILECTPKGVNKAFALDYLLKIMNRDKKDLIAF
                     GDEHNDTEMLAFAGKGYAMKNANPELLPYADEQISLTNDQDGVAKTLQDLFL"
     gene            1023..2441
                     /locus_tag="VQ862_000908"
     CDS             1023..2441
                     /locus_tag="VQ862_000908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000359314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HET3115275.1"
                     /translation="MDKLFKLKENGTDVRTEVLAGLTTFFAMSYILFVNPQILSQTGM
                     PAQGVFLATIIGAVAGTLMMAFYANLPYAQAPGMGLNAFFTFTVVFGLGYSWQEALAM
                     VFICGIISLIITLTNVRKMIIESIPNALRSAISAGIGVFLAYVGIKNAGLLKFTIDPG
                     NYTVVGEGADKAQATIAANSSAVPGLVSFNNPAVLVALAGLAITIFFVIKGIKGGIIL
                     SILTTTVLAIAVGLVDLSSIDFANNHVGAAFEDLKTIFGAALGSEGLGALVSDTARLP
                     ETLMAILAFSLTDIFDTIGTLIGTGEKVGIVATNGENHQSAKLDKALYSDLIGTTVGA
                     IAGTSNVTTYVESAAGIGAGGRTGLTALVVAICFAISSFFSPLLAIVPTAATAPILII
                     VGIMMLGSLKNIHWDDMSEAVPAFFTSIFMGFSYSITQGIAVGFLTYTLTKLVKGQVK
                     DVHVMIWILDALFILNYISMAL"
     gene            2494..3201
                     /locus_tag="VQ862_000909"
     CDS             2494..3201
                     /locus_tag="VQ862_000909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET3115276.1"
                     /translation="MKEKNMWKELLNRAGWILVFLLAVLLYQVPLVVTSILTLKEVAL
                     LQSGLIVTGISIVVLVLFIIGARKTQLASFNFSFFRTKDLARLGLSYLVIICSNILGS
                     ILLQLSNETTTANQSQINDMVQNSSLISSFFLLALLAPICEEILCRGIVPKKIFRGKE
                     NLGFVVGTIVFALLHQPSNLPSLLIYGGMSTVLSWTAYKTQRLEMSILLHMIVNGIAF
                     CLLALVVIMSRTLGISV"
     gene            3297..4277
                     /gene="folP"
                     /locus_tag="VQ862_000910"
     CDS             3297..4277
                     /gene="folP"
                     /locus_tag="VQ862_000910"
                     /EC_number="2.5.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydropteroate synthase"
                     /protein_id="HET3115277.1"
                     /translation="MMKSLEGVTDMSSKANHAKTAICGIINVTPDSFSDGGQFFVLEQ
                     ALQQARKLIAEGASMLDIGGESTRPRPGSSYVEIEEEIQRVVPVIKAIRKESDVLISI
                     DTRKSQVAEAALAAGANLVNDITGLMGDEKMAHVVAKAGAKVVIMFNPVMARPQHPSS
                     LIFPHFGFGQTFTEKELADFETLPIEEMMEAFFERALARAAEAGIAPENILLDPGIGF
                     GLTKKENLLLLRDLDKLHQKGYPIFLGVSRKRFVINILEENGFEVNPETELGFRNRDT
                     ASAHVTSIAARQGVEVVRVHDVASHRMAVEIASAIRLADEAENLDLKQYK"
     gene            4279..5601
                     /locus_tag="VQ862_000911"
     CDS             4279..5601
                     /locus_tag="VQ862_000911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000658404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional folylpolyglutamate
                     synthase/dihydrofolate synthase"
                     /protein_id="HET3115278.1"
                     /translation="MKEIENNQWIANYRTDQPHFGLERMVELLALRGNPHLKLKVLHI
                     GGTNGKGSTIAFLKKMLEKLGLRVGVFSSPYLIHYTDQISINGESISEARLEALMADY
                     QSLLEGEAVANLQGTTEFEIITALAYDYFASEQVDVAIMEVGMGGLLDSTNVCQPILT
                     GITTIGLDHVALLGDTLEAIAEQKAGIIKQGMPLVTGRIAPEALTVIDRIAEGKDAPR
                     LAYGTDYQVRHQESVVTGEVFDYTSAVRQGRFQTSLLGLYQIENAGMAIALLDTFCQE
                     DGRELASNDFLGQALEETSWPGRLEIVSRDPLMILDGAHNPHAIKALLVTLQERFADY
                     HKEILFTCIKTKALEDMLALLGAMPDTELTLTHFADSRATDESVLKEAAKSRNLSYQD
                     WHDFLDQNLTDKKEEKQTVRIVTGSLYFLSQVRAYLMERKNENGYTKD"
     gene            5582..6136
                     /gene="folE"
                     /locus_tag="VQ862_000912"
     CDS             5582..6136
                     /gene="folE"
                     /locus_tag="VQ862_000912"
                     /EC_number="3.5.4.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP cyclohydrolase I FolE"
                     /protein_id="HET3115279.1"
                     /translation="MDTQKIEAAVKMIIEAVGENANREGLQETPARVARMYQEIFSGL
                     GQTAEEHLSKSFEIIDDNMVVEKDIFFHTMCEHHFLPFYGRAHIAYIPDGRVAGLSKL
                     ARTVEVYSKKPQIQERLNIEVADALMDYLGAKGAFVVIEAEHMCMSMRGVRKPGTATL
                     TTVARGLFETDKDLRDQAYRLMGL"
     gene            6179..6991
                     /gene="folK"
                     /locus_tag="VQ862_000913"
     CDS             6179..6991
                     /gene="folK"
                     /locus_tag="VQ862_000913"
                     /EC_number="2.7.6.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-amino-4-hydroxy-6-
                     hydroxymethyldihydropteridine diphosphokinase"
                     /protein_id="HET3115280.1"
                     /translation="MDQLQIKDLEMFAYHGLFPSEKELGQKFVVSAILSYDMTKAATD
                     LDLTASVHYGELCQQWTTWFQETSEDLIETVAYKLVERTFESYPLVQEMKLELKKPWA
                     PVHLSLDTCSVTIHRRKQRAFIALGSNMGDKQANLKQAIDKLRARGIHILKESSVLAT
                     EPWGGVEQDSFANQVVEVETWLPAQDLLETLLAIESELGRVREVHWGPRLIDLDLLFV
                     EDQILYTDDLILPHPYIAERLFVLESLQEIAPHFIHPILKQPIRNLYDALKK"
     gene            complement(7036..7353)
                     /locus_tag="VQ862_000914"
     CDS             complement(7036..7353)
                     /locus_tag="VQ862_000914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF960 domain-containing protein"
                     /protein_id="HET3115281.1"
                     /translation="MAFTNTHMRSASFGIVTSLPDDIIDSFWYIIDHFLKNVFELEEE
                     LEFQLLNNQGKITFHFSSQHLPTAIDFDFNHPFDPRYPPRVLVLDMDGRETILLPEEN
                     DLF"
     gene            7710..8156
                     /gene="rplM"
                     /locus_tag="VQ862_000915"
     CDS             7710..8156
                     /gene="rplM"
                     /locus_tag="VQ862_000915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003083327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L13"
                     /protein_id="HET3115282.1"
                     /translation="MNKTTFMAKPGQVERKWYVVDATDVPLGRLSAVVASVLRGKNKP
                     TFTPHTDTGDFVIVINAEKVKLTGKKATDKIYYTHSNHPGGLKQISAGELRSKNAVRL
                     IEKSVKGMLPHNTLGRAQGMKLKVFVGAEHTHAAQQPEVLDISGLI"
     gene            8175..8567
                     /gene="rpsI"
                     /locus_tag="VQ862_000916"
     CDS             8175..8567
                     /gene="rpsI"
                     /locus_tag="VQ862_000916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002942223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HET3115283.1"
                     /translation="MSQAQYAGTGRRKNAVARVRLVPGTGKITVNKKDVEEYIPHADL
                     RLVINQPFAVTSTVGSYDVFVNVIGGGYAGQSGAIRHGIARALLQVDPDFRDSLKRAG
                     LLTRDSRKVERKKPGLKKARKASQFSKR"
     gene            complement(8829..9251)
                     /locus_tag="VQ862_000917"
     CDS             complement(8829..9251)
                     /locus_tag="VQ862_000917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001211071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HET3115284.1"
                     /translation="MRFIVETFPIFSISNDLLQLLTSWKKQQKYELAKFGIISNPEQF
                     IFTYIDTKGNINKPLHSDYLNNKMKTIRKRHPELTHATPHKLRHTGATLAKQAGMSLE
                     AISEALIHSDTGTTQIYVNTSNVVPMAVGEFALQSLKQ"
     gene            9398..9574
                     /locus_tag="VQ862_000918"
     CDS             9398..9574
                     /locus_tag="VQ862_000918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3115285.1"
                     /translation="MSLDIDKEKMTIMGIAFENRSVFKSVWYALSTNMIEGWRPTVSD
                     VEKLRDEALALGMT"
     gene            9976..12189
                     /locus_tag="VQ862_000919"
     CDS             9976..12189
                     /locus_tag="VQ862_000919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000688702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 31 protein"
                     /protein_id="HET3115286.1"
                     /translation="MKIFKGEFYRISVLTDKLVRLEYSRTGNFEDRTTQLIYNRDFGQ
                     VSLDYIETSNVLDIMTDYFHLHFNKGEFNAENLFIELKGNFAVYGSRWYFGESIETLK
                     GTARTLDKADGAISLEDGIISRNGIALLDDSQGFIWDEQSGYIERENQIDLYFFAYGH
                     DYRGAIRDFYHLTGSTPLLPRYALGNWWSRYWPYTSDEYLDLIDRFETEKIPLSIGVL
                     DMDWHITDIPARFGSGWTGYSWNRNLIPNPEQLLQQLHDRKLKLSLNVHPADGIRAYE
                     EAYPQIAKRLGLNVELEEPAIFDFFNPSFREAYFKDVHYELEKQGVDFWWIDWQQGTQ
                     GMLDPLWLLNHYHYQDSCKNAEGGLILSRYAGPGSHRYPVGFSGDTIISWNSLRFQPY
                     FTATASNIGYSWWSHDIGGHMLGDYDEELQTRWLQFGVFSPITRLHSSRSPFNSKEPW
                     FFSETTSKIMKKYLRLRHQMIPYLYTMNVKTHEEGAPLISPIYYFYPENDESYNVPNQ
                     YFFGTELMVAPIVEKMDLTFQSAKVDVWFPEGEWYDFFSEKKYTGGVKLSVYRDISTT
                     PVFAKSGAIIPLVGSEIGMGVDLPEVVDWYVFPGKQHSFEMLEDQNGQRYKTRLSIDW
                     EMGMVELALQGDSSIVPSNRKHRIHFKGTNVSIIELPNKNDTAKFEWKDNKRTSLNDE
                     VFRLLKTASLPYELKDRLLNQFINAKNSHDLMNILHHQDKELRGRLLEMIFTSQN"
     gene            complement(12411..12887)
                     /locus_tag="VQ862_000920"
     CDS             complement(12411..12887)
                     /locus_tag="VQ862_000920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione peroxidase"
                     /protein_id="HET3115287.1"
                     /translation="MTSLYDFSVLNQNNQATPLDSYRGKVLLIVNTATGCGLTPQYQG
                     LQELYERYQDQGFEILDFPCNQFMGQAPGSAEEINAFCSLHFQTTFPRFAKIKVNGKE
                     ADPLYVWLKDQKSGPLGKRVEWNFAKFLIGRDGQVFERFSSKTDPKQIEEAIQTLL"
     gene            13110..16313
                     /locus_tag="VQ862_000921"
     CDS             13110..16313
                     /locus_tag="VQ862_000921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001193686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored hyaluronate lyase"
                     /protein_id="HET3115288.1"
                     /translation="MQTKTKKLIVSLSSLVLSGFLLNHYMTVGAEETTTNTIQQSQKE
                     VQYQQRDTKNLVENGDFGQTEDGSSSWTGSKAQGWSAWVDQKNSSADASTRVIEAKDG
                     AITISSHEKLRAALHRMVPIEVKKKYKLRFKIKTDNKVGIAKVRIIEESGKDKRLWNS
                     ATTSGTKDWQTIEADYSPTLDVDKIKLELFYETGTGTVSFKDIELVEVAAQLSEDSQT
                     DKQLEEKIDLPIGKKHVFSLADYTYKVENPDVASVKNGILEPLKGGTTNVIVSKDGKE
                     VKKIPLKILASVKDTYTDRLDDWNGIIAGNQYYDSKNEQMAKLNQELEGKVADSLSSI
                     SSQADRTYLWEKFSNYKTSANLTATYRKLEEMAKQVTNPSSRYYQDETVVRTVRDSME
                     WMHKHVYNSEKSIVGNWWDYEIGTPRAINNTLSLMKEYFSDEEIKKYTDVIEKFVPDP
                     EHFRKTTDNPFKALGGNLVDMGRVKVIAGLLRKDDQEISSTIRSIEQVFKLVDQGEGF
                     YQDGSYIDHTNVAYTGAYGNVLIDGLSQLLPVIQKTKNPIDKDKMQTMYHWIDKSFAP
                     LLVNGELMDMSRGRSISRANSEGHVAAVEVLRGIHRIADMSEGETKQRLQSLVKTIVQ
                     SDSYYDVFKNLKTYKDISLMQSLLSDAGVASVPRPSYLSAFNKMDKTAMYNAEKGFGF
                     GLSLFSSRTLNYEHMNKENKRGWYTSDGMFYLYNGDLSHYSDGYWPTVNPYKMPGTTE
                     TDAKRADSDTGKVLPSAFVGTSKLDDANATATMDFTNWNQTLTAHKSWFMLKDKIAFL
                     GSNIQNTSTDTAATTIDQRKLESSNPYKVYVNDKEASLTEQEKDYPETQSVFLESSDS
                     KKNIGYFFFKKSSISMSKALQKGAWKDINEGQSDKEVENEFLTISQAHKQNGDSYGYM
                     LIPNVGRATFNQMIKKLESSLIENNETLQSVYDAKQGVWGIVKYDDSVSTISNQFQVL
                     KRGVYTIRKEGDEYKIAYYNPETQESAPDQEVFKKLEQAAQPQVQNSKEKEKSEEEKN
                     HSDQKNLPQTGEGQSILASLGFLLLGAFYLFRRGKNN"
     gene            16692..17077
                     /gene="tnpA"
                     /locus_tag="VQ862_000922"
                     /pseudo
     CDS             16692..17077
                     /gene="tnpA"
                     /locus_tag="VQ862_000922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005816675.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
     gene            complement(17456..18085)
                     /locus_tag="VQ862_000923"
     CDS             complement(17456..18085)
                     /locus_tag="VQ862_000923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 4-hydroxy-2-oxoglutarate
                     aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase"
                     /protein_id="HET3115289.1"
                     /translation="MTKSDTIIELKKQKIVAVIRGNTKEEGLQASIACIKGGIKAIEI
                     AYTNQYAGQIIKELVDLYQDDQSVCIGAGTVLDAVTARDAILAGANYVVSPSFHAETA
                     KMCNLYSTPYIPGCITLTEITTALEAGSEIIKLFPGSTLSPAYISAVKAPIPQVSVMV
                     TGGVGLNNIPQWFAAGADAVGIGGELNKLASQGNFDRISEIAQQYITLR"
     gene            complement(18095..19096)
                     /locus_tag="VQ862_000924"
     CDS             complement(18095..19096)
                     /locus_tag="VQ862_000924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar kinase"
                     /protein_id="HET3115290.1"
                     /translation="MTKILLFGEPLIRISPLDATSIGDHVASSTYFGGSEINIACNLQ
                     ALGISTKVFTALPANEIGDRFLTFLKQHQIDTSSICRLGDRIGLYYLENGFGCRQSEV
                     FYDRKHTSISQIRPNMLDMDSLFQGISHFHFSGITVAIGQEVRAILLLLLEEAKRRGI
                     VVSMDLNLRTKMISVLEAKYEFSKFARFTDYCFGIDPLMIDDQNLEMFPRDSASLEEV
                     ENRMRLLKEAYGFKAIFHTLRSSDEQDKNVYQAYALEELFEESVQLKTAVYQRIGSGD
                     AFISGALYQLLHHSSLKTTIDFAVASATLKCTLPGDHLSTSATSIENLLANAQDIIR"
     gene            complement(19127..19768)
                     /locus_tag="VQ862_000925"
     CDS             complement(19127..19768)
                     /locus_tag="VQ862_000925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RpiB/LacA/LacB family sugar-phosphate isomerase"
                     /protein_id="HET3115291.1"
                     /translation="MKIALINENSQASKNHIIYDSLKEATDKKDYQLFNYGMRGEEGE
                     SQLTYVQNGLMAAILLNTKAVDFVVTGCGTGVGAMLALNSFPGVVCGLAVDPTDAYLY
                     SQINGGNALSIPYAKGFGWGAELTLKLMFERLFAEEMGGGYPRERVIPEQRNARILNE
                     VKQITHNDLMTILKTIDQDFLKDTISGKYFQEYFFENCQDDEVAAYLKEVLAK"
     gene            complement(19787..20602)
                     /locus_tag="VQ862_000926"
     CDS             complement(19787..20602)
                     /locus_tag="VQ862_000926"
                     /EC_number="1.1.1.69"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000185867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gluconate 5-dehydrogenase"
                     /protein_id="HET3115292.1"
                     /translation="MTNTSFSIEQFSLKGKIALITGASYGIGFAIAKSYAEAGATIVF
                     NDINQDLVNKGIKAYREVGIEAHGYVCDVTDEDGIQAMVKQIEQEIGVIDILVNNAGI
                     IRRVPMCEMSAADFRKVIDIDLNAPFIVSKAVIPSMIKKGHGKIINICSMMSELGRET
                     VSAYAAAKGGLKMLTRNIASEYGGANIQCNGIGPGYIATPQTAPLRELQEDGSRHPFD
                     QFIIAKTPAARWGNPEDLMGPAVFLASDASNFVNGHILYVDGGILAYIGKQPE"
     gene            20873..21307
                     /locus_tag="VQ862_000927"
     CDS             20873..21307
                     /locus_tag="VQ862_000927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000706826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HET3115293.1"
                     /translation="MKIVLVGHGHFATGIYSSLQLIAGNQENVEAIDFVEGMSADELK
                     QKILLAISNEEEVLILSDLLGGSPFKVSSTIMGENPAKTMNVLSGLNLAMLMEAVFAR
                     MAHSFDEVVNKSVVAAQGGVVNGKELFSTDAEEEEEDFESGI"
     gene            21319..22509
                     /locus_tag="VQ862_000928"
     CDS             21319..22509
                     /locus_tag="VQ862_000928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003074342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HET3115294.1"
                     /translation="MIKKVTIEKIKSPERFLEVPLLTKEEVGQAIDKVIRQLELNLDY
                     FKEDFPTPATFDNVYPIMDNTEWTNGFWTGELWLAYEYSQQDAFKNIAHKNVLSFLDR
                     VNKRVELDHHDLGFLYTPSCMAEYKINGDGEAREAALKAADKLIERYQEKGGFIQAWG
                     DLGKKEHYRLIIDCLLNIQLLFFAYQETGDQKYYDIAESHFYASANNVIRDDASSFHT
                     FYFDPETGQPFKGVTRQGYSDDSCWARGQSWGVYGIPLTYRHLKDESCFDLFKGVTNY
                     FLNRLPKDHVSYWDLIFNDGSDQSRDSSATAIAVCGIHEMLKHLPEVDADKDIYKHAM
                     HAMLRSLIEYYANDQFTPGGTSLLHGVYSWHSGKGVDEGNIWGDYYYLEALIRFYKDW
                     NLYW"
     gene            22520..23011
                     /locus_tag="VQ862_000929"
     CDS             22520..23011
                     /locus_tag="VQ862_000929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000178618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system
                     mannose/fructose/N-acetylgalactosamine-transporter subunit
                     IIB"
                     /protein_id="HET3115295.1"
                     /translation="MTMPNIIMTRIDERLIHGQGQLWVKYLGCNTVIVANDEVSTDKM
                     QQTLMKTVVPDSVAMRFFPLQKVIDIIHKANPAQTIFIVVKDVKDALTLVEGGVPIKE
                     INIGNIHNAPGKEQVTRSIFLGEEDKAALKELSQTHQVTFNTKTTPTGNDGAVQVNIM
                     DYI"
     gene            23026..23805
                     /locus_tag="VQ862_000930"
     CDS             23026..23805
                     /locus_tag="VQ862_000930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000026606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HET3115296.1"
                     /translation="MSINVFQAILIGLWTAFCFSGMLLGIYTNRCIVLSFGVGIILGD
                     LPTALAMGAIGELAYMGFGVGAGGTVPPNPIGPGIFGTLMAITSAGKVSPEAALALST
                     PIAVAIQFLQTFAYTVRAGAPETAMKHLKNHNLKKFKFTLNATIWLFAFIGFTLGCLG
                     ALSMDTLLKLVDYIPPVLLTGLTVAGKMLPAIGFAMILSVMAKKELIPFVLLGYVCAA
                     YLNIPTIGIAIVGTIFALIEFYNKPKTADHVVEEEAHDDWI"
     gene            23792..24610
                     /locus_tag="VQ862_000931"
     CDS             23792..24610
                     /locus_tag="VQ862_000931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000148012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HET3115297.1"
                     /translation="MTGSNKLTKRDYLKTSLRAFFCQNGFNYSNYQGLGYANVMYPAL
                     KKHYGEDQEGFYQALEENCEFYNTNPHFLPFITSLHLVMLENGRPAKETRSIKMALMG
                     PLAGIGDSLSQFCLAPLFSTIAASFAQEGLVVGPILFFLAMNTILTAIKLSTGLYGYK
                     LGTTVIDKLSEQMATISRIANIIGVTVIAGLAATSVKIMVPITFAAGEVKADAKQSIV
                     SIQGMLDKVAPALLPALFTLLVYYLIKEKKWTTYKLVILTVIIGIIGSWLKIIA"
     gene            24610..24903
                     /locus_tag="VQ862_000932"
     CDS             24610..24903
                     /locus_tag="VQ862_000932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000381741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HET3115298.1"
                     /translation="MDTTLFYGIVIVLAVSPLLLSSFHSIRQQKLLRKQMEQRQEYLA
                     SLTSGDEVLLLSGIHGKIISIKDDLVSLQIAKGVVIYVEKESVMGKTKELLFK"
     gene            24925..26826
                     /locus_tag="VQ862_000933"
     CDS             24925..26826
                     /locus_tag="VQ862_000933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000657070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alginate lyase family protein"
                     /protein_id="HET3115299.1"
                     /translation="MKEERRQFFERVDGNQCRDYILSHCSKDYEKVKSSLERLMDNRF
                     MFDSPWDMEPCSKIHQIQPMVWDQVFEDDPEWSYMLNRQEYLLQFMIGYLVEGDKDYI
                     QKCKFFLFDWIEQVREFSPQSLMTRTLDTGIRSFTWLKLLLLLLKFDLLEEKELEKIL
                     VSLEKQIDFMKSYYRAKYTLSNWGILQTIPMLAIYHFFSDKMDLEEAYHFASEELKQQ
                     IETQILGDGSQFEQSILYHVEVYKALLDLCLLLPDLQDSYQELLEKMATYIQMMTGLD
                     GRTLAFGDSDSTETTEMLSLSAVVLNKEDLLNGLDVKVDLLSLLFLGREKVKRLQEFE
                     RRAWQPKSMIFEDSGHVCIKDEHRYLFFKNGPLGSAHSHSDENSFCLQYQGQPIFIDA
                     GRYSYREIYERYLLKSAWSHSTCIVDGKAPERITGSWEYEYYPHSLFCHHKEREGVHY
                     IEGAYWSAEPDLPYLHKRKILMLVEDVWLLVDDIRCQGQHEALIQFILDKDVTYQDGK
                     INQLRLWSEVDFDLEDTIISPKYNELERSSKLTKRQFFENQMLDYTIIAHESFEIIRH
                     SVYQTDDREVENALAFEVKNDETDKLILLLSEDIGVGEKLCLVDGTKMRGKCLVYDKI
                     NERMIRLQC"
     gene            26886..27887
                     /locus_tag="VQ862_000934"
     CDS             26886..27887
                     /locus_tag="VQ862_000934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000412458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HET3115300.1"
                     /translation="MEKKLTIKDIAEMAQTSKTTVSFYLNGKYEKMSQETREKIEKVI
                     HETNYKPSIVARSLNSKRTKLIGVLIGDITNSFSNQIVKGIEDIASQNGYQVMIGNSN
                     YSQESEDRYIESMLLLGVDGFIIQPTSNFRKYSRIIDEKKKKMVFFDSQLYEHRTSWV
                     KTNNYDAVYDMTQSCIEKGYEHFLLITADTSRLSTRIERASGFVDALTDANMRHASLT
                     IEDKHTNLEQIKEFLQKEIDPDEKTLVFIPNCWALPLVFTVIKELNYNLPQVGLIGFD
                     NTEWTCFSSPSVSTLVQPSFEEGQQATKILIDQIEGRNQEERQQVLDCSVNWKESTF"
     gene            complement(27997..28332)
                     /locus_tag="VQ862_000935"
     CDS             complement(27997..28332)
                     /locus_tag="VQ862_000935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000838135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3115301.1"
                     /translation="MKSLARLLIIHVFISIFLFFALISGAVSHTVLLLLLLFLPALNK
                     GLEKIQSKRIPVLNAALFFLLISFPQLLSNPVQWKFSIFLVVTIISSLAYFYNFYQVV
                     KEVDQKQLI"
     gene            complement(28343..28585)
                     /locus_tag="VQ862_000936"
     CDS             complement(28343..28585)
                     /locus_tag="VQ862_000936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3115302.1"
                     /translation="MKKEKKQLRYPGLKAGSIYGTVIFFIIPLIDTLTSENPNFISSL
                     LNTKHIFKTILGAFFFGVMIHIVDSLRIARAKKDQD"
     gene            complement(28596..29138)
                     /locus_tag="VQ862_000937"
     CDS             complement(28596..29138)
                     /locus_tag="VQ862_000937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000712356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3278 domain-containing protein"
                     /protein_id="HET3115303.1"
                     /translation="MKKETFTEKLIKRTYGISGPLDEYKRREADSIGNQVFIILFYLM
                     IFGNLIPLLLAYKYPQKVALIYPPLILVIALIAAGYVTYQMKKTGITVIEPDMLNEKE
                     SKQLHYLGLKAGLFFGLWMFFITPLLSILIDEGQDYFHSLLTIRNGVSSILGSIFFGA
                     SIQFLISRRIAKTKKNQDED"
     gene            complement(29154..29348)
                     /locus_tag="VQ862_000938"
     CDS             complement(29154..29348)
                     /locus_tag="VQ862_000938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001082472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET3115304.1"
                     /translation="MNRVKEFRKELGISQLELAKDIGVSRQTINMIENDKYNPTLELC
                     LNLARSLQTDLNSLFWEEDF"
     gene            29514..30464
                     /gene="rsmH"
                     /locus_tag="VQ862_000939"
     CDS             29514..30464
                     /gene="rsmH"
                     /locus_tag="VQ862_000939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(1402)-N(4))-methyltransferase
                     RsmH"
                     /protein_id="HET3115305.1"
                     /translation="MTKEFHHVTVLLHETIDMLDVKPDGIYVDATLGGAGHSEYLLSK
                     LSEKGHLYAFDQDQNAIDNAQKRLAPYIEKGMVTFIKDNFRHLQARLREAGVQEIDGI
                     CYDLGVSSPQLDQRERGFSYKKDAPLDMRMNQDASLTAYEVVNHYDYHDLVRIFFKYG
                     EDKFSKQIARKIEQAREVKPIETTTELAEIIKLVKPAKELKKKGHPAKQIFQAIRIEV
                     NDELGAADESIQQAMDMLALDGRISVITFHSLEDRLTKQLFKEASTVEVPKGLPFIPD
                     DLKPKMELVSRKPILPSAEELEANNRSHSAKLRVARKIHK"
     gene            30476..30793
                     /gene="ftsL"
                     /locus_tag="VQ862_000940"
     CDS             30476..30793
                     /gene="ftsL"
                     /locus_tag="VQ862_000940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsL"
                     /protein_id="HET3115306.1"
                     /translation="MAEKMEKTGQILQMQLKRFSRVEKAFYFSIAVTTLIVAISIIFM
                     QTKLLQVQNDLTKINAQIEEKKTELDDAKQEVNELLRAERLKEIANSHDLQLNNENIR
                     IAE"
     gene            30797..33049
                     /gene="pbpX"
                     /locus_tag="VQ862_000941"
     CDS             30797..33049
                     /gene="pbpX"
                     /locus_tag="VQ862_000941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000872287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 2X"
                     /protein_id="HET3115307.1"
                     /translation="MKWTKRVIRYATKNRKSPAENRRRVGKSLSLLSVFVFAIFLVNF
                     AVIIGTGTRFGTDLAKEAKKVHQTTRTVPAKRGTIYDRNGVPIAEDATSYNVYAVIDE
                     NYKSATGKILYVEKTQFNKVAEVFHKYLDMEESYVREQLSQPNLKQVSFGAKGNGITY
                     ANMMSIKKELEAAEVKGIDFTTSPNRSYPNGQFASSFIGLAQLHENEDGSKSLLGTSG
                     MESSLNSILAGTDGIITYEKDRLGNIVPGTEQVSQRTMDGKDVYTTISSPLQSFMETQ
                     MDAFQEKVKGKYMTATLVSAKTGEILATTQRPTFDADTKEGITEDFVWRDILYQSNYE
                     PGSTMKVMMLAAAIDNNTFPGGEVFNSSELKIADATIRDWDVNEGLTGGRMMTFSQGF
                     AHSSNVGMTLLEQKMGDATWLDYLNRFKFGVPTRFGLTDEYAGQLPADNIVNIAQSSF
                     GQGISVTQTQMIRAFTAIANDGVMLEPKFISAIYDPNDQTARKSQKEIVGNPVSKDAA
                     SLTRTNMVLVGTDPVYGTMYNHSTGKPTVTVPGQNVALKSGTAQIADEKNGGYLVGVT
                     DYIFSAVSMSPAENPDFILYVTVQQPEHYSGIQLGEFANPILERASAMKDSLNLQTTA
                     KALEQVSQQSPYPMPSVKDISPGDLAEELRRNLVQPIVVGTGTKIKNSSAEEGKNLAP
                     NQQVLILSDKAEEVPDMYGWTKETAETFAKWLNIELEFQGSGSTVQKQDVRANTAIKD
                     IKKITLTLGD"
     gene            33051..34031
                     /locus_tag="VQ862_000942"
     CDS             33051..34031
                     /locus_tag="VQ862_000942"
                     /EC_number="2.7.8.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000470804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-N-acetylmuramoyl-pentapeptide-
                     transferase"
                     /protein_id="HET3115308.1"
                     /translation="MFISISAGIVTFLLTLVGIPAFIQFYRKAQITGQQMHEDVKQHQ
                     AKAGTPTMGGLVFLITSVLVAFFFALFSSQFSNNVGMILFILVLYGLVGFLDDFLKVF
                     RKINEGLNPKQKLALQLLGGIIFYLFYERGGDILSVFGYPVHLGFFYIFFALFWLVGF
                     SNAVNLTDGVDGLASISVVISLSAYGVIAYVQGQMDILLVILAMIGGLLGFFIFNHKP
                     AKVFMGDVGSLALGGMLAAISMALHQEWTLLIIGIVYVFETTSVMMQVSYFKLTGGKR
                     IFRMTPVHHHFELGGLSGKGNPWSEWKVDFFFWGVGLLASLLTLAILYLM"
BASE COUNT        10306 a         6070 c         7607 g        10141 t
ORIGIN      
        1 tcattgagta tcagtatagg ttataagaat aagtcttgta gggttttggc aaccccatct
       61 tggtcgttgg taagggaaat ttgctcatct gcataaggga gtagctctgg attggcattt
      121 ttcatggcat aacccttccc agcaaaagcg agcatttcgg tatcattgtg ttcatctcca
      181 aaggcaatca aatctttttt gtcacgattc attatcttga gcaagtagtc caaagcaaag
      241 gccttgttga caccttttgg ggtacattca aggatattga gcggacctcc ccaggtattg
      301 atagaaagtt gatgctggta gaaggcgttc atgtcttttg ccaaggcata tttgtcactg
      361 gctctggtct gcaagaggat acagttaggg tccttggtca ccaattcagg ctggaattga
      421 tcttcaggct ggaaagcttc tacaccaaat agtttgggat tggcaatttc ttcattggga
      481 tttgtaatgt agaatttttt acgatattct ccagcgataa aatcggcttg aatgtcctct
      541 gaacgttgaa ccatatctag cagatatttt ttgtctacag tcaaacactt ttcaaaatcc
      601 caaacttggt ctggtaaatg agtaagggat ccgttgaagt taatcatagg agtgtctaag
      661 cccagttcac ggtaaaaatc ttttgacata cggtaagggc gacctgtcgt aataataacc
      721 tgatggcctt tttcagcaac ttttttgatg gtttttttgg taaagtcaga aatttgactg
      781 tctgagttga gcagggttcc atccaggtca actgcaataa tttttttcgt catatggacc
      841 tttctagtgt gttttcagat aagatgtctt ctattataac agaaagcagg cagaaaagca
      901 gattccaaac aaaaaatgaa attggattaa tttcttaaac aaatcaaaca aagacattga
      961 aaaagtgaat gataaatgat ataattctat tattgttcgt aaaaattaaa aggagattga
     1021 tgatggacaa attatttaaa ctaaaagaga acggtacaga cgttcgtaca gaggttctcg
     1081 ctggtttaac aactttcttt gcaatgagct atattctctt tgtaaaccca caaatacttt
     1141 cacaaacagg aatgcctgct cagggcgtct tcctagcgac gattattggt gcagtagcgg
     1201 gtaccctgat gatggctttt tatgctaact taccttatgc ccaagcgcca ggtatgggac
     1261 tcaatgcctt ctttaccttt acagttgtat tcgggcttgg ttattcttgg caagaagccc
     1321 tagctatggt cttcatctgt gggattattt cattgattat taccttgaca aatgttcgta
     1381 aaatgatcat tgaatcgatt cccaatgctc ttcgctcagc tatttcagct ggtatcggtg
     1441 tcttccttgc ctatgtaggg attaagaatg ctggactttt gaaattcacg attgatccag
     1501 gcaactatac tgttgtagga gaaggggctg acaaagctca agcaacgatt gcagcaaact
     1561 cttcagcagt tccaggattg gtcagcttta ataatccagc tgttttagtg gctcttgcag
     1621 gacttgccat tactatcttc tttgtcatca aagggattaa agggggaatt attctctcta
     1681 tcttgacaac aactgttctt gctattgcag ttggtttggt tgatttgtct agtatcgatt
     1741 ttgctaataa ccatgttggt gcagcttttg aagatttgaa gacaatcttt ggtgcagctc
     1801 ttggttcaga aggattggga gctttggttt cagatacagc tcgcttgcct gaaactctga
     1861 tggccattct tgccttctca ttgacagata tttttgacac aattggtacc ttgatcggta
     1921 caggtgaaaa agttggtatc gtagcgacaa atggtgaaaa tcaccaatca gccaaattgg
     1981 ataaggctct ttactctgat ttgattggaa cgacagtcgg tgccattgca ggtacttcaa
     2041 acgtaacgac ttatgttgag tctgctgctg gtatcggtgc tggtggacgt actggtttga
     2101 cagccttggt tgtagctatc tgttttgcga tttcaagctt ctttagccca cttctagcga
     2161 tcgtaccaac agcggctaca gctccaatct tgattatcgt tgggattatg atgcttggta
     2221 gcttgaaaaa tatccattgg gatgatatgt ctgaagcagt tcctgccttc ttcacatcta
     2281 tctttatggg attcagctac tctatcactc aagggattgc agttggtttc ttgacttaca
     2341 ctttgactaa gcttgttaaa ggtcaagtta aagatgttca tgtcatgatt tggattttgg
     2401 atgccttgtt tatccttaac tacatcagca tggccttata atagaatgac ccagggggat
     2461 ttcccccctt ttttaataca aaggagatag gtgatgaaag agaaaaatat gtggaaagaa
     2521 ttgttgaatc gtgcaggctg gattttggtc tttttacttg ccgtcctttt atatcaggtt
     2581 cccctagtgg ttacctctat tttgacttta aaagaagtag ccctgctaca gtcagggctg
     2641 atagttactg gtatttctat tgtggttctg gtgctattta ttattggagc tcgtaaaacg
     2701 caattggcaa gttttaattt ttcttttttt agaactaagg atttggcacg tttgggcttg
     2761 agttatttag tcattatctg ttcaaatata cttggttcta tcttgttgca actgtcaaat
     2821 gagacgacaa cagctaacca gtctcagatt aacgatatgg ttcagaatag ttctctgatt
     2881 tctagcttct tcttgctagc cttgcttgct ccaatttgtg aggaaatctt gtgccgtggg
     2941 attgttccta aaaagatttt ccgaggcaag gagaacttgg gatttgtagt cggtacgatt
     3001 gtgtttgctt tattgcatca accaagtaat ttaccttctt tattgattta tggaggtatg
     3061 tcgacagttc tatcttggac ggcctacaag acccaacgtt tggaaatgtc gatcttgctt
     3121 cacatgattg ttaatgggat tgctttctgt ttgttggctc ttgtggtgat tatgagtcgg
     3181 acattaggaa tttctgttta aaagttttta tgtaggaacc gacctctttc tactgggaaa
     3241 aagatgaatg caatcgtgtc catctttttc tttttatggt aaaatagaga aataatatga
     3301 tgaaaagcct tgagggagtg accgatatgt caagtaaagc taatcatgca aagacagcta
     3361 tttgcggaat tatcaatgta accccagatt ccttttcgga tggtggtcaa ttttttgttc
     3421 ttgagcaagc gctccagcag gctcgtaaat tgatagcaga aggagccagc atgctagata
     3481 tcggcggtga atcgactcgg cctcggccgg gaagtagcta tgttgagata gaagaggaaa
     3541 tccagcgtgt tgttccagtg attaaagcga ttcgcaagga aagtgatgtc ctcatctcta
     3601 ttgatactcg gaagagtcag gtggcagagg ctgctttggc tgctggtgcc aatctagtca
     3661 atgatatcac tggtcttatg ggtgatgaga aaatggccca tgtggttgct aaggctggtg
     3721 cgaaagtagt cattatgttt aacccagtta tggctcggcc tcagcatcct agttcgctta
     3781 tcttccctca ttttggtttt ggtcaaacct ttacagaaaa agagttagct gactttgaaa
     3841 cattgccaat cgaagaaatg atggaggctt tctttgaacg agcactagcg agagcggcag
     3901 aagctggtat tgcaccagaa aatatcctgt tggatccagg aattggcttt ggtctgacca
     3961 agaaagaaaa tctgcttctt ttacgggacc tggataaact acatcagaag ggctatccaa
     4021 tctttctcgg agtgtcgcgc aagcgatttg tcatcaatat cctagaggag aatggttttg
     4081 aagtcaatcc tgagacagag cttggtttcc gaaatcggga cacggcttcg gctcatgtaa
     4141 ctagtatcgc tgcgagacag ggtgtagaag tggtgcgcgt gcatgacgta gctagtcaca
     4201 ggatggcagt tgaaattgcc tctgccattc gtctggctga tgaagcggaa aatttagatt
     4261 taaaacaata taaataagat gaaagaaatt gaaaacaatc agtggattgc taactaccgg
     4321 acggatcaac cgcattttgg cttggaacga atggtggaac tgttagcttt gcgtggcaat
     4381 ccccatctca aactcaaggt cctccatatc ggagggacta acggcaaggg ctcgactatt
     4441 gcttttttga aaaagatgct agaaaagcta gggctgagag ttggcgtgtt tagctcgccc
     4501 tatctcattc attacacaga ccagattagc atcaatgggg aatcgatctc agaagcgagg
     4561 ctagaagctc tcatggcaga ttatcagtct ttgctggagg gagaagcggt cgccaattta
     4621 cagggcacaa ccgagtttga gattatcaca gccctggcct atgactactt tgcctcagag
     4681 caagtagatg tggccatcat ggaagttggc atgggtggac ttttggatag taccaatgtc
     4741 tgtcagccca ttttgacagg aattacaact attggcttgg atcatgtggc cctacttggt
     4801 gacaccttgg aggccatagc agagcagaag gcaggtatta tcaaacaagg gatgcccttg
     4861 gtaacagggc gtattgctcc agaagccttg actgtgattg accgcattgc ggaagggaaa
     4921 gatgcgccga gacttgccta cgggacagat tatcaggttc gtcatcaaga aagtgtggtg
     4981 acaggggaag tctttgacta tacaagtgct gtcagacaag gtcgcttcca gactagcctg
     5041 cttggtttgt accaaataga gaatgctggg atggccatag ctttacttga tactttttgt
     5101 caagaagatg gtcgagagct agcaagcaat gactttcttg gtcaagcctt ggaagaaaca
     5161 agttggccag ggcgtttgga aatcgtgtca agagatccct tgatgatttt ggatggagcc
     5221 cacaatcccc atgctatcaa ggccttgttg gtaaccttgc aagaacgttt tgcagattat
     5281 cataaggaaa tcctcttcac ttgtatcaaa accaaggcct tggaggatat gttggccttg
     5341 ttgggagcca tgccagatac cgagcttact ctaacacatt ttgcggatag tcgggcgacg
     5401 gatgaaagcg tgctgaaaga ggcagctaag tctagaaatc tcagctacca agattggcat
     5461 gattttctag atcagaattt gacagataaa aaagaagaga aacaaacagt taggattgtc
     5521 acaggttcct tgtatttctt gagccaagtg agggcctatc tgatggagag gaagaacgag
     5581 aatggataca caaaagattg aagcagctgt aaaaatgatt atcgaggctg taggagagaa
     5641 cgctaatcgc gagggcttgc aggaaacacc tgctcgtgta gcccgtatgt atcaagagat
     5701 tttttcaggt cttggtcaaa cagcagagga acatttgtca aaatcctttg aaattattga
     5761 cgataatatg gtggtagaaa aggatatctt tttccatacc atgtgtgaac accacttctt
     5821 gccattttat ggtagagcgc acattgccta cattccagat ggtcgtgtgg caggcttgtc
     5881 taagctagcc cgtacggttg aagtttattc gaaaaaacca caaattcaag aacgtttgaa
     5941 tatcgaagtg gccgatgcct tgatggacta tctaggtgct aaaggagcct ttgttgtcat
     6001 tgaggcggaa catatgtgta tgagtatgcg tggtgttaga aaaccaggca ctgcaacctt
     6061 gacgacagta gctcgtggtt tatttgaaac agataaggac ctccgcgacc aagcttatcg
     6121 tttaatgggg ctataaaaag aatccgcttc aagcggattt ttctagaaag gaatcattat
     6181 ggatcaactg cagattaagg atttggaaat gtttgcctat catggtcttt ttcctagtga
     6241 gaaagaattg gggcagaaat ttgtcgtttc agccatccta tcctatgata tgaccaaggc
     6301 agctacagac ttggatttaa cagcctctgt ccattacgga gaattgtgtc agcagtggac
     6361 gacttggttt caggaaacga gtgaggattt gattgaaacg gtagcctata aactggtgga
     6421 acgtaccttt gagtcttatc ctcttgtcca agaaatgaag ttggaactga aaaaaccttg
     6481 ggcaccggtg catttgtcac tagatacttg ctcggtaacc attcatcgcc gcaagcaacg
     6541 agcctttatc gccctaggaa gcaatatggg agataagcaa gcaaacttga agcaagccat
     6601 tgacaaactg cgagctcgtg gcatccatat tctcaaagag tccagtgtct tagcgacgga
     6661 gccttggggt ggagtggagc aggatagctt tgccaatcaa gtggttgagg tggaaacctg
     6721 gctaccagca caagacttgt tagaaacctt gttagccatt gagtcagagc tgggacgggt
     6781 gagagaagtg cattggggac ctcgtttgat tgatttggac ttgctctttg tggaggacca
     6841 gatcctttat acagacgacc tcatattgcc tcatccttac atagcggaac gcctttttgt
     6901 ccttgagtcc ttacaggaaa ttgcgcctca ttttatccat ccgatattaa aacaaccgat
     6961 ccgcaacttg tatgatgctt tgaaaaaata gaaaaactct agttttcagt tacttgcaac
     7021 tgaaggctag agtttttaaa ataggtcatt ttcttctggg aggaggatag tttctctacc
     7081 gtccatgtct aaaaccagta ctcttggggg ataacgaggg tcgaaaggat ggttaaagtc
     7141 aaaatcaatg gctgtaggga ggtgttgact tgaaaagtgg aaggtaatct ttccttggtt
     7201 attaagcaat tgaaactcga gttcttcttc caattcaaag acatttttta agaaatgatc
     7261 gatgatatac caaaaagagt caatgatgtc atcaggcaag ctggtaacaa tgccaaaact
     7321 agcagaccgc atgtgggtat tggtaaaagc catatctctg tcccctttct tttcccttat
     7381 catacagcaa ataggattaa aaatcaagaa aaggtgattt tttgaaaagg attttaacta
     7441 cagggaaaaa gaaggaaaaa aattcccaaa aatctaccga agttaatagg taaattccca
     7501 aattaacttg attatataac tttcagttac tttgagaagt taccgaaaaa tatttttcat
     7561 atctattgac ttttaggggt gaaatttggt atgatagtag gcggtattgt ttaccccatt
     7621 tgaaaggccc cggaaccttc caaatacttt tcgatgggaa ggaacaccca tcaccgtaaa
     7681 caaaaatcga actatatata ggagaaatca tgaacaaaac aacatttatg gctaaaccag
     7741 gccaagttga acgtaaatgg tacgtagttg acgcaactga tgtaccactt ggacgtcttt
     7801 ctgcagtagt tgctagcgta cttcgcggaa aaaacaaacc aacatttaca ccacacactg
     7861 atacaggtga cttcgtgatt gttatcaatg ctgaaaaagt taaattgact ggtaaaaaag
     7921 caactgataa aatctactac actcactcaa accacccagg tggattgaaa caaatctctg
     7981 caggtgaact tcgttctaaa aatgcagtac gtttgattga gaaatcagtt aaaggtatgc
     8041 ttccacacaa tacacttgga cgcgctcaag gtatgaagtt gaaagtattt gttggagctg
     8101 agcacactca cgctgcacaa caaccagaag ttcttgacat ttcaggactt atctaaggaa
     8161 aggaacaata aagtatgtca caagcacaat atgcaggtac tggacgtcgt aaaaacgctg
     8221 ttgcacgcgt tcgccttgtt ccaggaactg gtaaaatcac tgttaacaaa aaagatgttg
     8281 aagagtacat cccacacgct gaccttcgtc ttgtcatcaa ccaaccattc gcagttactt
     8341 caactgtagg ttcatacgac gttttcgtta acgttatagg tggtggatac gctggtcaat
     8401 caggagctat ccgtcacggt atcgctcgtg cccttcttca agtagaccca gacttccgcg
     8461 attcattgaa acgcgcagga cttcttacac gtgactcacg taaagttgaa cgtaagaaac
     8521 caggtcttaa gaaagctcgt aaagcatcac aatttagtaa acgttaattc gaaagaatta
     8581 ctatacttat acagagcacc tttcggggtg ttcttttttt atactttctt actaaattgg
     8641 tgcaattgac acagttgttg cgactttagt cgcttacaaa tgtggctgca acctgacaag
     8701 gtcagttgcc tcaaaacgtt aatcaataca attatatcaa cgtttcaaag cactcaagag
     8761 tttacctcat gggtgctttt tttatgtttt ttgaaaaagt tcacctcaaa gtttacctta
     8821 ttttcacctt attgttttag agactgtaag gcaaattcac cgacggccat agggactaca
     8881 ttagaagtat tgacataaat ctgtgttgta cctgtgtcgc tatgtattag agcttcagaa
     8941 atggcttcta agctcattcc tgcttgttta gcgagcgttg ctccggtatg acgtagtttg
     9001 tgtggcgtag cgtgtgtaag ctctgggtgt cgttttctga tagttttcat cttattattg
     9061 agatagtcag aatgtaaagg tttattgata ttgcctttgg tatctatgta agtaaagatg
     9121 aattgttctg gattactgat gataccaaac tttgccagtt catatttttg ttgttttttc
     9181 catgaagtca gaagttgaag taagtcatta gaaatagaga aaatgggaaa tgtttccaca
     9241 ataaaacgca tattatcaga tggttaatgc gttttatatt tgggtttgag gcttataaaa
     9301 taggataagc gtactgaaaa cttagatatg acaaacaaaa taaaattttt aaaagctaca
     9361 gagaaacatg gtataatgta tctaaaggag gtagcatatg tccttagata tagataaaga
     9421 aaagatgaca atcatgggaa tagcttttga aaaccgatcc gtttttaaga gtgtttggta
     9481 tgctttaagt acaaatatga ttgaaggatg gcgacctacg gttagtgatg ttgaaaaatt
     9541 acgagatgaa gctcttgctc tggggatgac ttaatgaagc gcaactgtta tgaatcttat
     9601 gactatgttg atccggataa tttatatacc gatccgggtt cttcagttct aagaaataag
     9661 caggaaggaa aaaagcacgc gagcttgaat atcgtatgat tgctagtaag agtttgaaat
     9721 tatttatcaa tcctatctta gttaatagtt taaaagtagt ttgtttcaca actgcataag
     9781 cttagaaaag ttgaaaagtg ataactcttt aataaactct tggtttgtta aaagatattt
     9841 tgtccactac atttttttca attgactatt atttgtcata gatataacag atagaacatt
     9901 gcattcagaa taatgaaaaa cgcatcaaaa atggtgcgtt ctgtttttat gctaccataa
     9961 aaggaggaaa acaaattgaa aatttttaag ggagagtttt atcgaatctc tgtattaaca
    10021 gacaagctag taaggttaga atactctcga actggaaatt ttgaggatag aacgacacaa
    10081 cttatctata atagagattt tggccaagtt tcgttagatt atatcgagac atcaaatgta
    10141 ctagatatta tgacggacta ttttcatctg cactttaata aaggagaatt taacgccgaa
    10201 aatttattta tagaattaaa aggaaatttt gccgtatatg gtagtcgctg gtattttggt
    10261 gaatctattg aaacgttaaa aggaacagct cggactctgg ataaggcaga tggagcaatc
    10321 tcgttagaag atggaattat tagccgaaat ggtatagcct tattggatga ttctcaagga
    10381 tttatttggg atgaacaatc tggttatatt gagagagaaa atcaaattga cctgtatttc
    10441 tttgcctatg ggcatgatta tagaggagca atcagagact tttaccattt gactggttca
    10501 acacccttgt tgccaagata tgctttaggc aattggtgga gtagatattg gccttatacg
    10561 tcggatgaat acttggattt aatagacaga tttgaaacag agaaaattcc attatctatc
    10621 ggtgtgttag atatggattg gcatataact gacattccag ctcgttttgg aagtggctgg
    10681 acaggatata gttggaatag aaacttaata ccaaatccag aacagttatt gcaacaactt
    10741 catgatagaa agttaaaact ctccttaaat gtccatcctg ctgatgggat acgggcttat
    10801 gaagaagctt atcctcaaat cgcaaaacgg ttggggttaa atgtagaact agaagaacct
    10861 gctatttttg atttttttaa tccctctttt agggaagcct actttaaaga tgttcattat
    10921 gagctagaaa agcagggagt agatttttgg tggattgact ggcaacaagg gacacaaggt
    10981 atgctagatc cactttggct tttaaaccat tatcactatc aggatagttg taaaaatgca
    11041 gaaggtggtt tgattttatc aagatatgca ggtcctggta gtcaccgcta ccctgttggt
    11101 ttttcagggg acactattat tagttggaat tccttaagat ttcaacccta ttttacagcg
    11161 acagcatcta atatcggtta tagttggtgg agtcatgata tcggtggaca tatgttgggg
    11221 gattatgacg aagagctaca aactagatgg ctacagtttg gtgtttttag tccgattact
    11281 cgattacata gttctagaag tccttttaat agtaaagaac cttggttctt ttcagaaaca
    11341 acatctaaga ttatgaagaa ataccttcgt ttgagacatc agatgattcc ctatctatat
    11401 accatgaatg taaagacaca tgaggaaggt gccccattaa tcagtccaat ctattatttc
    11461 tatccagaga atgatgagag ctataatgtt ccaaaccaat acttttttgg aacagaactg
    11521 atggtggctc ccattgtaga aaagatggat ttgacattcc aatctgcaaa agtagatgta
    11581 tggttccctg aaggtgaatg gtatgacttc ttttcagaga aaaaatacac aggtggtgtg
    11641 aagttaagtg tttataggga catctcgact acgcctgtgt ttgcaaaaag tggtgcaatc
    11701 attcccttgg ttggttctga gataggtatg ggtgttgatt tacctgaggt tgtagattgg
    11761 tatgtattcc cagggaaaca acattctttt gaaatgcttg aagatcaaaa tggtcaaaga
    11821 tataaaacaa gattatcaat cgattgggaa atgggaatgg tagagttagc attacaagga
    11881 gattctagta tcgttccaag caatagaaaa catagaattc attttaaagg aacgaatgtg
    11941 tctataattg aattgccaaa taagaatgat acagctaaat ttgaatggaa agataataaa
    12001 aggacatctt taaatgacga agtttttaga ctactaaaga cagcttctct tccatatgaa
    12061 ttaaaagata gattgttaaa tcaattcatc aatgccaaaa actctcatga cttaatgaat
    12121 atcttgcatc atcaggataa ggaattgaga gggcgtttgt tggaaatgat atttactagc
    12181 caaaactaat tgaaataatt agaaagtcat ttgtttagtg tatatgaaga ttctgtatgg
    12241 tattcgttat cactggtcac attgaaattg tgaaataagc acctacaaca tagactttac
    12301 aacacttcat gtttcatatc atggggtgtt tttctattta agtcaaagcc aatcaaaaaa
    12361 tctcactatt catcaggtta aaggaaacct aatcatagtg agattgtgaa ttatagtaga
    12421 gtttgtatcg cctcttcaat ttgttttggg tctgtttttg aagaaaagcg ttcaaagact
    12481 tgcccatctc gaccgatgag aaacttagcg aaattccatt cgactcgttt tcctagtggg
    12541 ccagatttct ggtcttttaa ccagacatag agagggtctg cttccttacc gttgacctta
    12601 atcttggcaa aacgtgggaa ggtggtttga aaatgtaggc tacagaaggc gttgatttcc
    12661 tctgcgctgc cgggtgcttg tcccataaac tgattgcaag ggaaatccaa tatttcgaag
    12721 ccctgatctt gatagcgttc atagagttct tgaagtccct ggtactgggg cgttaaacca
    12781 catccagtag cagtgttgac aatcaagaga actttgccac gatagctatc caagggagtt
    12841 gcttggttgt tttggttcaa aacggaaaaa tcataaagtg aagtcatgag ggcctctttt
    12901 ctttttctac attgtaacag tttttacttt tttcgtcgag tcggatggaa gatattgttg
    12961 aagaataagc cctcaatatg atagaaatcg tttacaaata actttaaaaa tggtatgatt
    13021 taactaaacc ggtttactta gttgctataa atctctaatt tgagatttag ttcctattga
    13081 ttttacaata tgtttattgg agtgtataca tgcaaacaaa aacaaagaag ctcattgtga
    13141 gtttgtcttc acttgtttta tcaggatttt tattaaacca ttatatgaca gttggagcgg
    13201 aagaaacgac tacgaatacc attcagcaaa gccagaagga agttcagtat cagcaaaggg
    13261 atacaaaaaa tttagttgaa aatggtgatt ttggtcagac ggaggacgga agcagttcgt
    13321 ggacaggaag caaagctcag gggtggtcag cttgggtaga ccagaagaat agttctgcag
    13381 atgcctcaac tcgagtcatt gaggctaagg atggggctat cactatctca agccatgaga
    13441 aattaagggc agcgcttcac cgtatggttc ctattgaagt taagaaaaag tataaactgc
    13501 gtttcaagat taaaacagat aataaagtcg ggattgccaa agttcgtatc attgaggaaa
    13561 gtggtaagga caagcgattg tggaattctg caacgacgtc aggaacaaag gactggcaga
    13621 ccattgaagc agactatagc ccgactttag atgttgataa aatcaagctg gagttattct
    13681 atgaaacagg aactgggact gtttccttta aggatattga gctggtagag gtagcagccc
    13741 agctttctga ggattctcaa acagataaac agcttgagga aaagattgat ttaccaattg
    13801 gaaaaaaaca tgttttttct cttgcggact atacttataa ggtagaaaat cctgacgttg
    13861 cttcagtcaa aaatggaatt ttagaacctc ttaagggagg gacaaccaat gtcattgtca
    13921 gtaaagatgg caaggaagtg aaaaagattc ctttgaagat tctagcctct gttaaggata
    13981 catacacaga ccgtttggat gactggaatg gcatcattgc tgggaatcaa tactatgatt
    14041 ctaaaaatga acagatggcc aaattaaacc aggaattgga aggaaaggta gctgatagcc
    14101 tatccagtat ttcaagtcag gcggaccgca cctatttgtg ggaaaaattt tcaaattata
    14161 aaacgtctgc aaatctgact gccacttatc ggaaattgga ggagatggcc aagcaagtga
    14221 ccaatccttc ttctcgttat tatcaagatg aaactgtcgt tcgaacagtc agggattcca
    14281 tggaatggat gcataaacat gtctacaata gtgaaaagag cattgttggg aactggtggg
    14341 attatgaaat cggtacacct cgtgccatca acaatacctt gtctctgatg aaagaatact
    14401 tctctgatga ggaaattaaa aaatatacag atgtgattga aaaatttgta ccagatcccg
    14461 aacatttccg aaagacgact gataacccat ttaaggctct aggtggaaac ttagttgata
    14521 tgggaagagt aaaagtaata gctggtttac tgcgtaagga tgatcaagaa atttcttcta
    14581 ccattcgctc gattgagcaa gtgttcaagt tggtagacca aggtgaaggt ttttatcaag
    14641 atggatccta tatcgaccac accaatgttg cctatacggg tgcttatggg aatgttttga
    14701 ttgatggcct gtctcaactg ttgccagtca ttcaaaagac caagaatcca atcgataaag
    14761 ataaaatgca aaccatgtac cactggattg ataaatcgtt tgctcctttg ctggtgaatg
    14821 gagagctgat ggatatgagt cgtggacgct cgatcagtcg tgcaaatagc gaggggcacg
    14881 tggccgcagt agaagtacta agagggattc accgaatagc ggatatgtct gaaggagaaa
    14941 ccaaacaacg tttgcagagt cttgtgaaga ccattgttca atcggatagt tattatgatg
    15001 tctttaagaa tttgaagact tataaggata tcagtttgat gcaatccttg ttaagtgatg
    15061 caggagtcgc aagtgttcca agaccaagtt acctatctgc ctttaacaag atggataaaa
    15121 cagccatgta caatgcagag aaagggtttg gatttggctt gtcactcttt tccagtcgta
    15181 ccttgaatta cgaacacatg aacaaggaaa ataaacgtgg ttggtatacg agtgatggga
    15241 tgttctatct ttacaatggc gatttgagtc actatagcga tggctactgg ccaacagtta
    15301 atccatataa gatgcctggt acaacagaga cggatgctaa gagagcggat agcgatacag
    15361 gtaaagtttt accgtctgct ttcgttggaa cgagcaaact agatgatgcc aatgcgacag
    15421 caaccatgga tttcaccaac tggaatcaaa cattgactgc tcataagagc tggtttatgc
    15481 tgaaggataa gatcgccttt ttaggaagca atatccaaaa cacttcaaca gatactgctg
    15541 caactacaat tgaccagaga aaactggaat caagtaatcc atataaagtc tatgtcaatg
    15601 ataaagaagc ctcccttaca gaacaagaaa aggattatcc tgaaacccaa agtgtctttt
    15661 tagaatcgtc cgattcgaaa aagaatattg gttacttttt ctttaagaag agttcaatca
    15721 gtatgagtaa ggctttgcaa aagggagcct ggaaggatat caatgaagga cagtcagaca
    15781 aggaagttga aaatgaattt cttacgatta gtcaggctca taagcaaaat ggagattctt
    15841 atggctatat gctcatccct aacgtgggtc gtgccacctt caatcaaatg ataaaaaagt
    15901 tagaaagtag cctcatcgaa aataacgaaa cccttcagtc tgtttatgat gccaaacaag
    15961 gagtttgggg cattgtgaaa tatgatgatt ctgtctctac tatttccaac caattccaag
    16021 ttttgaaacg tggagtctat accattcgaa aagaagggga tgaatataag attgcctact
    16081 ataatcctga aacccaggaa tcagctccag atcaggaagt ctttaaaaag ctagagcaag
    16141 cagctcagcc acaagtacag aattcaaaag aaaaggaaaa atctgaagag gaaaagaacc
    16201 attcggatca aaagaatctc cctcagacag gagaaggtca gtcaatcttg gcaagtctag
    16261 ggttcttgct acttggggca ttttatctat tccgtagagg aaagaacaac taatttgttc
    16321 atcatctaga tgaattacat gaaactgtgg aaaatagaaa aaatccgaag aaggccaaat
    16381 atcttcggat ttttctttta aaaaagataa gttgatactt atctttttta cttcattatg
    16441 tgactatagc gttttgaaac tagaatagga cgttataact actaaaagat ttctataaat
    16501 tcatttgatt ttcctaatca atttgttcgt atcctatttc actccactat attagtccgt
    16561 ctcgctccgt gaggtgcgag acaaaacaac cacccgctat gcgggtgcgc gtcgaaggtt
    16621 ataccaaaaa aactctaaac gcgatacaat aaaggtgttc aatccaattg taaagcgaaa
    16681 ggagaaaaaa tatggcacaa aaggctcata gtttatctca cacaaagtgg aggtgttcta
    16741 tcacattgtg ttcaccccta agtatagacg aaaagtcatc tataatcaat atagaagtag
    16801 tttaggcgaa atatttcatc gcttgtgtag ttataaaggt gttgaaatga tcgagggtca
    16861 cttaatgcca gaccatgtac acatgttagt cagtattccg tcgaggctaa gtgtttcaag
    16921 ttttatgggg tatttaaaag gcaaaagtgc actcatgatg tttgacaaac acgccaatct
    16981 caagtacaag tttgggaatc ggcatttctg ggcggaaggt tattatgtaa gtccagtagg
    17041 gcttaatgaa gccacactta agaaatatag tcaagattaa agaaattatc cagtggatga
    17101 tttcttcacg agtatgaaaa tttgagaact agtaaagtat gatatatagt aaaatgaaat
    17161 aagaacagga caaaatcgat caggacagtc aaatcgattt ttaacaatgt tttagaagta
    17221 gaggtgtact attccagttt caatctacta tagcactaga taaattgagt gtaaaagaat
    17281 atgaggatcc ctttagggat agtggtaagt aataccaaag tatcttaaag aggcaagtga
    17341 cgagtcaaga gcaataaggc ttgaacaacg tgaaagccag cgtctttagg cgctggctgg
    17401 taatttgagc ttatagctct gggataaacc acccgtttga cgggtggtta tgattttatc
    17461 tgagtgtaat atactgttgg gcaatctcgc tgatgcggtc aaagttgcct tgggaagcga
    17521 gtttattgag ttcgccacca attccaacgg catctgcacc agcagcgaac cattgaggga
    17581 tgttgtttag gccgactcct ccggttacca ttacggaaac ttgtgggatc ggtgccttga
    17641 ctgcagagat atatgctgga ctgagagtac tacctgggaa gagtttgatg atttcactac
    17701 cggcttcaag tgcagtcgtg atctctgtga gggtaataca gcctggaatg tacggtgtgc
    17761 tgtagagatt gcacattttc gcagtttcag catggaaaga tggagaaaca acgtaatttg
    17821 ctccggctag aatggcatct ctagcagtta cggcatcaag cacagtacct gcaccgatac
    17881 aaacactctg atcgtcctga tacaagtcta caagttcctt gatgatttgc cctgcatact
    17941 gattggtata ggcgatttca atagctttga taccgccctt gatacaagca atcgaggctt
    18001 gcagtccttc ttcctttgta tttcctcgaa tgacagcgac aattttctgt ttttttagtt
    18061 caataatcgt atctgatttg gtcatgtaat tctcctaacg aatgatatct tgtgcatttg
    18121 ccagtaaatt ttcaatacta gttgcggaag tggagagatg gtctcctgga agagtgcatt
    18181 tgagagttgc gctcgcaact gcaaagtcaa tggtagtttt tagggaggaa tgatggagta
    18241 gttggtaaag ggcaccagat ataaaggcat ccccgctacc aattcgttga tagactgcag
    18301 tttttagttg gacagactct tcaaatagtt cttctagagc ataggcttga tagacatttt
    18361 tgtcttgctc atcactagag cggagggtat ggaaaatggc cttgaaacca taggcttctt
    18421 ttaaaagtcg catgcgattt tccacctctt ctaggctagc actgtctctt ggaaacatct
    18481 ctagattttg gtcatcaatc atgagaggat caataccgaa gcaatagtca gtaaaacgtg
    18541 caaacttaga aaattcatac ttggcttcta ggactgaaat catctttgtt ctcagattga
    18601 gatccattga aacgacaatt cctcggcgct tggcttcttc caagagtagg agaaggatcg
    18661 cacggacctc ttgaccgata gctacggtga ttccactaaa atgaaaatgg ctaatcccct
    18721 gaaagagaga atccatatct agcatgtttg gccgaatctg gctgatactc gtatgcttac
    18781 gatcgtagaa aacttcactt tgacgacaac caaagccgtt ctccaaatag tagaggccga
    18841 ttcgatcgcc aagccgacag attgaactgg tatcgatttg gtgctgtttc aagaatgtga
    18901 gaaaacgatc tccaatctcg ttggcaggga gtgcggtaaa gactttcgtt gagataccca
    18961 gggcttgcaa attacaagcg atgttaattt ctgatccgcc aaaataagtc gaactggcaa
    19021 catgatcgcc gatactggtg gcatctaatg gtgagattcg aattaatggt tcgccaaaca
    19081 gtaatatttt cgtcatccat tagttccttt ctggtttaga atagctttac ttagctaata
    19141 cttctttcaa ataagcagcg acttcatcat cttggcagtt ttcaaagaag tattcttgga
    19201 agtatttgcc agagatggtg tctttgagga agtcttggtc gattgtttta aggatggtca
    19261 tcaaatcatt gtgggtgatt tgtttcacct cgtttaagat acgagcgttg cgttgttcag
    19321 ggattacacg ttctcttggg tagccaccgc ccatttcttc agcaaataag cgttcaaaca
    19381 tcaatttgag ggtcagttct gccccccagc caaatccttt ggcataaggg atagacaagg
    19441 cgttaccacc attgatttga gaataaaggt aagcgtcagt tgggtccact gctagaccac
    19501 agacaacacc agggaagctg tttaaagcaa gcatagcccc tacacccgta ccacagccgg
    19561 taacaacaaa gtcaactgcc tttgtattta aaaggatggc agccattagt ccgttctgca
    19621 cataagttaa ttgactttct ccttcttctc cacgcatacc atagttaaat aattggtagt
    19681 cttttttatc tgtcgcttct tttagactat cgtaaataat gtgattcttg ctagcttgac
    19741 tattttcatt gattaatgcg attttcataa gatcttcttt ctatttttac tcaggttgtt
    19801 ttccgatgta ggctaagata ccgccatcta catataggat gtggccattg acaaaattgc
    19861 tggcatcact agcgagaaag acagcagggc ccatcaaatc ttcaggattt ccccaacgtg
    19921 cagcaggtgt ttttgcaatg atgaactggt caaatgggtg gcgagaacca tcttcttgca
    19981 actcacgaag aggtgctgtt tgaggagtgg caatataacc cggtccaatt ccgttacatt
    20041 ggatattggc tccaccgtat tcagacgcaa tgttgcgggt caacattttc aagccccctt
    20101 tagcagcagc ataagcgcta actgtttcac gtcccagttc gctcatcatc gaacaaatat
    20161 tgataatctt tccatgccct ttctttatca tagaaggaat aactgccttt gaaacgataa
    20221 atggtgcgtt taagtcaata tcgatgacct tacggaaatc agcggcgctc atttcgcaca
    20281 ttggaactcg gcggataata ccagcgttat taacgaggat gtcaatgaca ccaatctctt
    20341 gttcgatttg cttgaccatg gcttggatac cgtcctcgtc tgtcacgtca cagacatatc
    20401 catgggcttc gatgccaact tcacgataag ctttaatccc tttattgacc agatcttgat
    20461 tgatatcgtt aaagacaata gtagcgccgg cttcagcgta ggatttggca atagcaaatc
    20521 caattccata agaagcgccg gtgatgaggg caatttttcc ttttaaagaa aactgctcaa
    20581 ttgagaatga tgtatttgtc atttgatact tcctttcaaa tttgttaaga cttctctata
    20641 accaaattat attctagtaa accggttttg tcaataaata aatattttta tttataaaaa
    20701 gatttatttt ccttaaaaat ggaatatttt gaaatttctg tctattaaaa tgattaaaaa
    20761 gataatgaaa gcgctaatat ttttttaaaa aaactattga caagataaaa ataaaggatt
    20821 acaatgggga atataaagta aaccggtaaa cctaaacaag aaaggagaaa agatgaaaat
    20881 tgtacttgta gggcatggac attttgctac agggatttat agttctttac aattgattgc
    20941 aggcaatcaa gaaaatgtgg aggcaattga ctttgtggaa ggaatgtcag cagatgaact
    21001 caagcaaaaa atcttacttg caatttcaaa tgaagaagaa gttttaatcc taagtgatct
    21061 cttgggagga tcgccattca aggtttcttc taccataatg ggagaaaatc cagccaaaac
    21121 aatgaatgtt ctctcgggtt tgaacttagc catgttaatg gaagcagtct ttgctagaat
    21181 ggctcatagc tttgatgagg ttgttaataa atcagtagtg gcggcccagg gcggagtcgt
    21241 aaatggtaaa gaattgtttt caacggatgc agaggaagag gaagaagatt tcgaatcggg
    21301 tatttaaagg gtaaaagaat gataaaaaag gttacgattg aaaaaataaa atcgcctgag
    21361 cgcttcttag aagtaccact tctgacgaaa gaagaagtcg gccaggcaat cgataaggtt
    21421 attcggcagt tagaactcaa ccttgactat ttcaaggaag atttcccgac gccagctacc
    21481 tttgataatg tctatccaat catggataac acggaatgga ccaatggttt ctggacagga
    21541 gaactgtggt tggcttatga atacagtcaa caggatgcat ttaaaaacat cgctcataaa
    21601 aatgttcttt ctttcctgga tcgtgtcaat aagagagtag aattggatca ccatgatctc
    21661 ggcttcttgt acacaccgtc ttgtatggct gaatataaga taaatggaga tggagaggct
    21721 agagaagcag ccttgaaagc tgcagataag ttgattgaac gctatcaaga aaaaggtggt
    21781 tttattcaag cttggggaga cttgggcaag aaagagcatt accgtttgat tatcgactgc
    21841 ttgctcaata tccaactctt attctttgct tatcaagaaa caggcgatca aaaatactac
    21901 gatattgcag aaagccattt ctatgcttca gctaataatg taatccgtga tgacgcttcg
    21961 tccttccaca ccttctattt tgatcctgag acaggtcaac cctttaaagg tgtaacgaga
    22021 caagggtata gtgatgattc atgctgggca cgtggtcaat catggggagt ctatggtatt
    22081 cctttgactt atcgtcactt aaaagacgag tcctgctttg acttgtttaa gggtgtgacc
    22141 aattatttct tgaatcgtct gccaaaagat catgtgtctt attgggattt gatttttaat
    22201 gatggtagtg atcaatcacg agattcttca gcaacagcta tcgccgtctg tgggattcat
    22261 gaaatgctaa aacatctccc agaggtggat gctgacaaag atatttataa acatgctatg
    22321 catgccatgc ttcgttcctt gatcgaatat tatgcaaatg atcaatttac ccctggtggg
    22381 acaagtctcc tccacggtgt gtactcatgg cattcaggta aaggagtgga tgaaggcaat
    22441 atctggggtg actactatta cctagaagcc cttatccgtt tctacaaaga ctggaaccta
    22501 tattggtagg aggagaaata tgacaatgcc aaatattatt atgacccgta tcgatgaacg
    22561 gttgattcat ggacaaggac aactttgggt aaaataccta ggttgtaata cggtcattgt
    22621 tgccaatgac gaagtaagca cggacaagat gcaacaaact ctgatgaaaa cagttgtgcc
    22681 agactcagtt gccatgcgtt tcttcccttt gcaaaaggtg attgatatca ttcacaaggc
    22741 taatcctgct caaacgatct ttatcgttgt aaaggatgta aaggacgctt taaccttggt
    22801 agaaggtggt gtccctatca aagaaatcaa tattgggaac attcacaatg cccctggtaa
    22861 agagcaagtg acacgctcca tcttcctggg tgaagaggac aaggcagccc tcaaggaatt
    22921 aagccaaact catcaagtaa catttaatac gaaaacaact ccaacaggaa atgatggagc
    22981 tgttcaagtc aacattatgg actatattta aaagaggaga tcgttatgtc gattaatgta
    23041 tttcaagcga ttttaattgg attatggaca gctttctgtt ttagtggaat gctgttagga
    23101 atttacacca atagatgtat tgttctgtca tttggtgtcg gaattattct aggtgatctg
    23161 cctactgctc ttgcaatggg agctattggt gaattggctt atatgggatt cggtgttggt
    23221 gctggaggta ctgttccacc aaacccaatc ggacctggta tctttggtac cttgatggct
    23281 atcactagtg ctggtaaagt cagtccagaa gcggctcttg ccctctctac tccgattgct
    23341 gtggcgattc aattcttaca aactttcgcc tacactgtac gtgctggtgc gcctgaaacg
    23401 gcgatgaagc acttgaaaaa ccataatttg aagaaattca agttcactct aaatgcaaca
    23461 atttggttgt ttgcctttat tggatttacc ttgggttgct tgggtgccct ttcaatggat
    23521 accttgttga aactcgtaga ctacattcca ccggtattac ttacaggttt gacagttgct
    23581 ggtaaaatgc tcccagctat cggttttgcg atgatcttgt cagtgatggc taagaaagag
    23641 ttgattccct ttgtcttgtt gggatatgtt tgtgcagctt atctaaacat cccaacaatt
    23701 ggtattgcaa ttgtaggtac tatctttgct ttgattgaat tttataacaa gccaaaaaca
    23761 gcggatcatg tggtagagga ggaagcacac gatgactgga tctaacaaat taacaaaacg
    23821 tgattatctt aaaacgtctt tgcgggcatt cttttgtcaa aatggattta actatagtaa
    23881 ctatcaaggg ttgggatatg ccaatgtaat gtatcctgct ttgaaaaaac actatggaga
    23941 ggatcaggaa ggtttctacc aagccttgga agaaaactgt gaattctata ataccaatcc
    24001 acacttcctg ccttttatta ccagcttgca ccttgtaatg ttggaaaatg gccgtccggc
    24061 aaaagaaaca cgtagcatca agatggcctt gatgggacca ttggcaggta ttggggattc
    24121 tctttctcaa ttctgtttag ctccattgtt ctcaaccatc gcagcttcgt ttgctcaaga
    24181 aggcttggtt gtcggtccaa tcttgttctt ccttgcgatg aatacgattt taacagcgat
    24241 taaattgtca actggtctgt atggatacaa actaggaaca actgtgattg ataaactaag
    24301 cgaacagatg gcaacgattt ctcgtattgc caatattatc ggtgtaaccg taattgctgg
    24361 tttggcagcg acatctgtta agattatggt gccgattacc tttgctgcag gggaagttaa
    24421 agcagacgct aaacaaagta tcgtaagtat tcagggaatg cttgataagg ttgctccagc
    24481 tcttctacca gccctattta cacttttagt ttactacttg atcaaagaaa agaaatggac
    24541 aacatataaa ctcgttattt taacagttat catcggaatt atcggaagct ggcttaagat
    24601 tatagcttaa tggatacaac attgttttat ggaatagtga ttgtcttggc agtgagtccc
    24661 cttttactgt caagctttca ttctattcgt cagcaaaagt tgcttcgcaa acagatggag
    24721 caacgacaag agtatttagc ttctttaaca tctggtgatg aagtgttgtt attgtctgga
    24781 attcatggaa aaatcatttc tatcaaagat gacttggtct ccttgcagat tgcaaaaggt
    24841 gtggtcatct atgtagaaaa ggaaagtgta atgggaaaga caaaagaact gctttttaag
    24901 tagttctttt tctggtaata gataatgaaa gaagaaagaa gacaattttt tgaaagagtc
    24961 gatggaaacc aatgtcgtga ttatatcttg tcccactgtt caaaagacta tgagaaagtc
    25021 aagagttccc ttgaacgctt gatggacaat cgttttatgt ttgatagtcc ttgggatatg
    25081 gagccttgtt caaaaatcca tcaaatccag ccgatggtat gggatcaagt atttgaagat
    25141 gatccagaat ggtcttatat gctcaatcga caagaatatc tcttgcagtt tatgataggg
    25201 tatctggtag aaggagataa ggactatatt caaaagtgca agttctttct atttgattgg
    25261 attgagcagg tgagagaatt ttctcctcaa tccttgatga ctagaacctt ggatacgggt
    25321 attcgttcct ttacttggtt gaaactactc ttgctcctct tgaaatttga cttgctagag
    25381 gagaaagaac tagagaaaat tttggtcagt ctagaaaagc agattgactt tatgaaaagc
    25441 tactatcgcg ccaagtacac ccttagtaac tgggggattt tacaaacaat tccgatgctt
    25501 gctatctatc atttcttttc agataagatg gacctagaag aagcttacca ttttgcttca
    25561 gaggagttga aacagcaaat tgagacacag attttaggag atggaagcca gtttgaacag
    25621 tcgattctct atcatgtaga ggtttataaa gccttgctgg atttgtgtct cttgcttcca
    25681 gacttgcaag atagttacca agagttgctg gaaaagatgg cgacctatat tcaaatgatg
    25741 acaggcttag atggacggac tttggctttt ggtgatagcg attctacaga aacgacagaa
    25801 atgttgagcc tgtctgctgt ggttttgaac aaggaagacc ttcttaacgg tctggatgtt
    25861 aaagtcgatt tgcttagcct cttgttcctg gggcgagaaa aggtcaagcg actgcaggaa
    25921 tttgaaagga gagcttggca gcctaagtcc atgatctttg aagactctgg acatgtctgc
    25981 attaaggatg aacatcgtta tctatttttc aaaaatggtc cgctaggaag tgcccatagc
    26041 catagtgacg agaatagttt ttgcttacag tatcaaggcc aacctatttt catagatgct
    26101 gggcgttatt cttatcggga gatatatgaa cgttatctct taaagagtgc ttggagtcat
    26161 tcgacctgca ttgtagatgg gaaagctccg gaaagaatca cgggatcctg ggaatatgaa
    26221 tactatcctc actccctgtt ttgtcaccat aaagaaaggg agggagtgca ttatattgag
    26281 ggggcttatt ggtcagcaga acctgatttg ccttatcttc acaagagaaa aatcctcatg
    26341 ttggtagagg atgtctggct cttggtagat gacatcaggt gtcaaggtca gcatgaggcg
    26401 ttgattcagt ttatccttga caaggatgtg acctatcaag atgggaaaat caatcagttg
    26461 agactatgga gtgaagttga ttttgatttg gaagatacca tcatttctcc taaatacaat
    26521 gagcttgaaa gaagtagcaa gctcaccaag cgccaattct ttgagaatca gatgctggat
    26581 tataccatca ttgcgcatga gagttttgaa atcatccgtc attctgtcta ccagacagat
    26641 gatcgtgaag tggaaaatgc tctggctttt gaagtgaaaa atgacgaaac agacaagctg
    26701 attctgttat taagcgagga tattggtgta ggtgaaaaat tgtgcctcgt tgacggaaca
    26761 aaaatgcgtg gaaaatgtct agtatatgat aaaataaatg agagaatgat tcgcttgcag
    26821 tgctagaaat aggcattttg aatagtgaat atgttataat aagtattagt aggaggtgtt
    26881 ttagattgga gaagaaactg accataaaag acattgcgga aatggctcag acctcgaaaa
    26941 caaccgtgtc attttaccta aacgggaaat atgaaaaaat gtcccaagag acacgtgaaa
    27001 agattgaaaa agttattcat gaaacaaatt acaaaccgag cattgttgcg cgtagcttaa
    27061 actccaaacg aacaaaatta atcggtgttt tgatcggtga tattaccaac agtttctcaa
    27121 accaaattgt taagggaatt gaggatatcg ccagccagaa tggctaccag gtaatgatag
    27181 gaaatagtaa ttacagccaa gagagtgagg accggtatat tgaaagcatg cttctcttgg
    27241 gagtagacgg ctttattatt cagccgacct ctaatttccg aaaatattct cgtatcatcg
    27301 atgagaaaaa gaagaaaatg gtcttttttg atagtcagct ctatgaacac cggactagct
    27361 gggttaaaac caataactat gatgccgttt atgacatgac ccagtcctgt atcgaaaaag
    27421 gttatgagca ttttctcttg attacagcgg atacgagtcg tttgagtact cggattgagc
    27481 gggcaagtgg ttttgtggat gctttaacag atgctaatat gcgtcacgcc agtctaacca
    27541 ttgaagataa gcatacgaat ttggaacaaa ttaaggaatt tttacaaaaa gaaatcgatc
    27601 ccgatgaaaa aactctggta tttatcccta actgttgggc cctacctcta gtctttaccg
    27661 ttatcaaaga gttgaattat aacttgccac aagttgggtt gattggtttt gacaatacgg
    27721 agtggacttg cttttcttct ccaagtgttt cgacgctggt tcagccctcc tttgaggaag
    27781 gacaacaggc tacaaagatt ttgattgacc agattgaagg ccgcaatcaa gaagaaaggc
    27841 aacaagtctt ggattgtagt gtgaattgga aagagtcgac tttctaaaat gaaggaaaat
    27901 gacttgcaat ctctgttaag aaataaaata atcccaccta gaacaagcta ggtgggatta
    27961 tttgcctatg aaatgagaaa ttatgggagc aagctcctaa atcaactgtt tttgatctac
    28021 ttctttaact acttgataaa agttatagaa gtaggccaaa cttgaaatga tggttacgac
    28081 taggaatatt gaaaatttcc attggacagg gttgcttaaa agttgtggaa aggatatgag
    28141 gagaaagaag agggctgcgt tgaggacagg tatccgtttt gattgtattt tctcaagtcc
    28201 tttattgagc gcaggaagaa agaggagtag gagtagtaaa actgtatgag aaacagctcc
    28261 tgaaataagg gcgaagaaaa ggaaaatact gataaaaaca tgaatgatca gtagtctagc
    28321 tagtgatttc ataaggcacc tcctaatcct ggtctttttt agctcttgca atacgaagtg
    28381 agtcgacaat atgtatcatc actccgaaaa agaaagctcc cagtatagtt ttaaaaatat
    28441 gttttgtatt tagaagagaa ctgataaaat ttggattttc acttgttagg gtatcaatga
    28501 gtggaattat aaaaaatatc actgttccat aaattgaacc tgctttcaga ccaggataac
    28561 gtaactgttt cttttctttt ttcatgagtt tcctcctaat cctcatcttg atttttctta
    28621 gtttttgcaa tgcgacggga gatgaggaac tgtatgctcg ctccgaagaa aatagaaccg
    28681 agaatgcttg atacaccatt tcttatagtg agaagagaat gaaaatagtc ctgaccttca
    28741 tctatgagta tactgagaag aggagttata aaaaacatcc atagaccaaa gaacaaacct
    28801 gctttaagac ctaggtagtg tagttgcttg ctttctttct cattcagcat atctggttca
    28861 atgactgtga tgcctgtttt tttcatttgg taggtgacat agccagcagc gatgagggca
    28921 atcactaaaa tcagaggagg atagattaga gccacttttt gagggtattt ataggccaga
    28981 aggagtggaa taagatttcc gaaaatcatc agataaaaga ggatgataaa gacttggttc
    29041 ccaatactat cggcctcacg ccgtttgtat tcgtcaaggg gaccagaaat accgtatgtg
    29101 cgtttgatca gtttttcagt gaaggtttct tttttcatga gtttgctcct tttttaaaaa
    29161 tcttcctccc aaaagagact gttgaggtca gtttggaggc tgcgggcgag attgagacag
    29221 agttccaagg ttggattgta cttgtcgttt tcaatcatat tgatagtctg tctcgagaca
    29281 ccgatatcct tggcgagttc gagctgggaa atacccaatt ccttgcgaaa ttctttcaca
    29341 cgattcatct gatctccttt ttgatttatg tcgtatatat ttgactttat tatagtcttt
    29401 taaacataaa gtgtcaagta tttttgacat attttttgaa gaaatagtag tctccttgtc
    29461 ctatttgtct gacaagtgca agctggtcgg atttgtggta aaatagataa gatatgacaa
    29521 aagaatttca tcatgtaacg gtcttactcc acgaaacgat tgatatgctt gacgtaaaac
    29581 ctgacggtat ctacgttgat gcgactttgg gcggagcagg acatagcgag tatttattaa
    29641 gtaaattaag tgaaaaaggc catctctatg cctttgacca ggatcagaat gccattgaca
    29701 atgcgcaaaa acgcttggca ccttacattg agaagggaat ggtgaccttt atcaaggata
    29761 acttccgtca tttacaggca cgtttgcgcg aagctggtgt tcaggaaatt gatggaattt
    29821 gttatgactt gggagtgtct agtcctcaat tggaccagcg tgagcgtggt ttttcttata
    29881 aaaaggatgc gccactggac atgcggatga atcaggatgc tagtctgaca gcctatgaag
    29941 tggttaatca ctatgactat catgatttgg ttcgtatttt cttcaaatac ggtgaggata
    30001 aattctctaa acagattgcg cgtaagattg agcaagcgcg tgaagtgaag ccgattgaga
    30061 caacgactga gttagcagag attatcaagt tggtcaaacc tgccaaggaa ctcaagaaga
    30121 agggtcatcc tgctaagcag attttccagg ctattcgaat tgaagtcaat gatgaactgg
    30181 gggcggcaga tgagtccatc cagcaggcta tggatatgtt ggctctggat ggtagaattt
    30241 cagtgattac ctttcattcc ttagaagacc gcttgaccaa gcaattgttc aaggaagctt
    30301 caacagttga agttccaaaa ggcttgcctt tcatcccaga tgatctcaag cccaagatgg
    30361 aattggtgtc ccgtaagcca atcttgccaa gtgcggaaga gttagaagcc aataaccgct
    30421 cgcactcagc caagttgcgc gtggccagaa aaattcacaa gtaagaggga aaaagatggc
    30481 agaaaaaatg gaaaaaacag gtcaaatact acagatgcaa cttaaacggt tttcgcgtgt
    30541 ggaaaaagct ttttactttt ccattgctgt aaccactctt attgtagcca ttagtattat
    30601 ttttatgcag accaagctct tgcaagtgca gaatgatttg acaaaaatca atgcgcagat
    30661 agaggaaaag aagaccgaat tggacgatgc caagcaagag gtcaatgaac tattacgtgc
    30721 agaacgtttg aaagaaattg ccaattcaca cgatttgcaa ttaaacaatg aaaatattag
    30781 aatagcggag taagatatga agtggacaaa aagagtaatc cgttatgcga ccaaaaatcg
    30841 gaaatcgccg gctgaaaaca gacgcagagt tggaaaaagt ctgagtttat tatctgtctt
    30901 tgtttttgcc atttttttag tcaattttgc ggtcattatt gggacaggca ctcgctttgg
    30961 aacagattta gcgaaggaag ctaagaaggt tcatcaaacc acccgtacag ttcctgccaa
    31021 acgtgggact atttatgacc gaaatggagt cccgattgct gaggatgcaa cctcctataa
    31081 tgtctatgcg gtcattgatg agaactataa gtcagcaacg ggtaagattc tttacgtaga
    31141 aaaaacacaa tttaacaagg ttgcagaggt ctttcataag tatctggaca tggaagaatc
    31201 ctatgtaaga gagcaactct cgcaacctaa tctcaagcaa gtttcctttg gagcaaaggg
    31261 aaatgggatt acctatgcca atatgatgtc tatcaaaaaa gaattggaag ctgcagaggt
    31321 caaggggatt gattttacaa ccagtcccaa tcgtagttac ccaaacggac aatttgcttc
    31381 tagttttatc ggtctagctc agctccatga aaatgaagat ggaagcaaga gcttgctggg
    31441 aacctctgga atggagagtt ccttgaacag tattcttgca gggacagacg gcattattac
    31501 ctatgaaaag gatcgtctgg gtaatattgt acccggaaca gaacaagttt cccaacgaac
    31561 gatggacggt aaggatgttt atacaaccat ttccagcccc ctccagtcct ttatggaaac
    31621 ccagatggat gcttttcaag agaaggtaaa aggaaagtac atgacagcga ctttggtcag
    31681 tgctaaaaca ggggaaattc tggcaacaac gcaacgaccg acctttgatg cagatacaaa
    31741 agaaggcatt acagaggact ttgtttggcg tgatatcctt taccaaagta actatgagcc
    31801 aggttccact atgaaagtga tgatgttggc tgctgctatt gataataata cctttccagg
    31861 aggagaagtc tttaatagta gtgagttaaa aattgcagat gccacgattc gagattggga
    31921 cgttaatgaa ggattgactg gtggcagaat gatgactttt tctcaaggtt ttgcacactc
    31981 aagtaacgtt gggatgactc tccttgagca aaagatggga gatgctacct ggcttgatta
    32041 tcttaatcgt tttaaatttg gagttccgac ccgtttcggt ttgacggatg agtatgctgg
    32101 tcagcttcct gcggataata ttgtcaacat tgcgcaaagc tcatttggac aagggatttc
    32161 agtgacccag acacaaatga ttcgtgcctt tacagctatt gctaatgacg gtgtcatgct
    32221 ggagcctaaa tttattagtg ccatttatga tccaaatgat caaactgctc ggaaatctca
    32281 aaaagaaatt gtgggaaatc ctgtttctaa agatgcagct agtctaactc ggactaacat
    32341 ggttttggta gggacggatc cggtttatgg aaccatgtat aaccacagca caggcaagcc
    32401 aactgtaact gttcctgggc aaaatgtagc cctcaagtct ggtacggctc agattgctga
    32461 cgagaaaaat ggtggttatc tagtcggggt aaccgactat attttctcgg ctgtatcgat
    32521 gagtccggct gaaaatcctg attttatctt gtatgtgacg gtccaacaac ctgaacatta
    32581 ttcaggtatt cagttgggag aatttgccaa tcctatcttg gagcgggctt cagctatgaa
    32641 agactctctc aatcttcaaa caacagctaa agctttggag caagtaagtc aacaaagtcc
    32701 ttatcctatg cctagtgtca aggatatttc acctggtgat ttagcagaag aattgcgtcg
    32761 caatcttgta caacccatcg ttgtgggaac aggaacgaag attaaaaaca gttctgctga
    32821 agaagggaag aatcttgccc cgaaccagca agtccttatc ttatctgata aagcagagga
    32881 agttccagat atgtatggtt ggacaaagga gactgctgag acctttgcta agtggctcaa
    32941 tatagaactt gaatttcaag gttcgggctc tactgtgcag aagcaagatg ttcgtgctaa
    33001 cacagctatc aaggacatta aaaaaattac attaacttta ggagactaat atgtttattt
    33061 ccatcagtgc tggaattgtg acatttttac taactttagt aggaattccg gcctttatcc
    33121 aattttatag aaaggcgcaa attacaggcc agcagatgca tgaagatgtc aaacagcatc
    33181 aggcaaaagc tgggactcct acaatgggag gtttggtttt cttgattact tctgttttgg
    33241 ttgctttctt tttcgcccta tttagtagcc aattcagcaa taatgtggga atgattttgt
    33301 tcatattagt cttgtatggc ttggtcggat ttttagatga ctttctcaag gtctttcgta
    33361 aaatcaatga ggggcttaat cctaagcaaa aattagctct tcagcttcta ggtggaatta
    33421 tcttctatct tttctatgag cgtgggggcg atatcctgtc tgtctttggt tatccagttc
    33481 atttgggatt tttctatatt ttcttcgctc ttttctggct agtcggtttt tcaaacgcag
    33541 taaacttgac agacggtgtt gacggtttag ctagtatttc cgttgtgatt agtttgtctg
    33601 cctatggagt tattgcctat gtgcaaggtc agatggatat tcttctagtg attcttgcca
    33661 tgattggtgg tttgctcggt ttcttcatct ttaaccataa gcctgccaag gtctttatgg
    33721 gtgatgtggg aagtttggcc ctaggtggga tgctggcagc tatctctatg gctctccacc
    33781 aagaatggac tctcttgatt atcggaattg tatatgtttt tgaaacaact tctgttatga
    33841 tgcaagtcag ttatttcaaa ctgacaggtg gtaaacgtat tttccgtatg acgcctgtac
    33901 atcaccattt tgagcttggg ggattgtctg gtaaaggaaa tccttggagc gagtggaagg
    33961 ttgacttctt cttttgggga gtgggacttc tagcaagtct cctgacccta gcaattttgt
    34021 atttaatgta agaatggcat cctgatgttt cagggtgttt ttgtatttaa atacacaatg
    34081 aaaatcaaag aacaaactag aaagctaact ttaggctgct caaa
//
LOCUS       DAVBOD010000018        33646 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 640-05
            SAMEA1012484-rid20186543.denovo.018, whole genome shotgun sequence.
ACCESSION   DAVBOD010000018 DAVBOD010000000
VERSION     DAVBOD010000018.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012484
            Sequence Read Archive: ERR059358
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 33646)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 33646)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979948.1
            Genome Coverage       :: 595x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:03:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,266
            CDSs (total)                      :: 2,219
            Genes (coding)                    :: 2,091
            CDSs (with protein)               :: 2,091
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 71 of 128
            Pseudo Genes (incomplete)         :: 50 of 128
            Pseudo Genes (internal stop)      :: 33 of 128
            Pseudo Genes (multiple problems)  :: 22 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33646
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012484-rid20186543.denovo.018"
                     /strain="NIG 640-05"
                     /db_xref="taxon:1313"
     gene            complement(399..1088)
                     /gene="rplA"
                     /locus_tag="VQ862_000943"
     CDS             complement(399..1088)
                     /gene="rplA"
                     /locus_tag="VQ862_000943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L1"
                     /protein_id="HET3115309.1"
                     /translation="MAKKSKQLRAALEKIDSTKAYSVEEAVALAKETNFAKFDATVEV
                     AYNLNIDVKKADQQIRGAMVLPNGTGKTSRVLVFARGAKAEEAKAAGADFVGEDDLVA
                     KINDGWLDFDVVIATPDMMALVGRLGRVLGPRNLMPNPKTGTVTMDVAKAVEESKGGK
                     ITYRADRAGNVQAIIGKVSFEAEKLVENFKAFNETIQKAKPATAKGTYVTNLTITTTQ
                     GVGIKVDVNSL"
     gene            complement(1296..1721)
                     /gene="rplK"
                     /locus_tag="VQ862_000944"
     CDS             complement(1296..1721)
                     /gene="rplK"
                     /locus_tag="VQ862_000944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004226069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11"
                     /protein_id="HET3115310.1"
                     /translation="MAKKVEKLVKLQIPAGKATPAPPVGPALGQAGINIMGFTKEFNA
                     RTADQAGMIIPVVISVYEDKSFTFVTKTPPAAVLLKKAAGVEKGSGTPNKTKVATVTR
                     AQVQEIAETKMPDLNAANVESAMRMIEGTARSMGFTVVD"
     gene            complement(2030..2746)
                     /locus_tag="VQ862_000945"
     CDS             complement(2030..2746)
                     /locus_tag="VQ862_000945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000747760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M15 family metallopeptidase"
                     /protein_id="HET3115311.1"
                     /translation="MKKRYLVVTALLALSLAACSQEKAKNEDGTAKTEQTAKADGTVG
                     SKSQGAAQKKAEVVNKGDYYSIQGKYDEIIVANKHYPLSKDYNPGENPTAKAELVKLI
                     KAMQEAGFPISDHYSGFRSYETQTKLYQDYVNQDGKAAADRYSARPGYSEHQTGLAFD
                     VIGTDGDLVTEEKAAQWLLDHAADYGFVVRYLKGKEKETGYMAEEWHLRYVGKEAKEI
                     AASGLSLEEYYGFEGGDYVD"
     gene            complement(2827..3631)
                     /locus_tag="VQ862_000946"
     CDS             complement(join(2827..3261,3263..3631))
                     /locus_tag="VQ862_000946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS5 family transposase"
                     /protein_id="HET3115312.1"
                     /translation="MNDEASKQLTDARFKRLVGVQRTTFEEMLAVLKTAYQLKHAKGG
                     RKPKLSLEDLLMATLQYVREYRTYEEIAADFGIHESNLLRRSQWVEVTLVQSGFTISR
                     TPLSSEDTVMIDATEVKINRPKKELANYSGKKKCHAMKAQAIVTSQGRIVSLDITVNY
                     CHDMKLFKMSRRNIGQAGKILADSDYQGLMKIYPQAQIPRKSSKLKPLIAEDKAYNHA
                     LSKDRSKVENILAKVKTFKMFSTTYRNHRKRFGLRMNLIAGIINHELGF"
     gene            complement(3639..4079)
                     /locus_tag="VQ862_000947"
     CDS             complement(3639..4079)
                     /locus_tag="VQ862_000947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000335589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HET3115313.1"
                     /translation="MCLICQRIELIKKGENPYFVKELETGYLVIGDHQYFAGYSLFLA
                     KEHVTELHHLKKETRLRFLEEMSVVQEAVAKAFAAEKMNIELLGNGDAHLHWHLFPRR
                     TGDMNGHGLNGRGPVWWVPFEEMTAETRQAKPDEIRLPAKQNMV"
     gene            complement(4081..5118)
                     /locus_tag="VQ862_000948"
     CDS             complement(4081..5118)
                     /locus_tag="VQ862_000948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001077203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M42 family metallopeptidase"
                     /protein_id="HET3115314.1"
                     /translation="MNQTVEYIKELTAIASPTGLTREISNYLVKTLEGFGYQPVRTAK
                     GGVNVTIKGQNDEQHRYVTAHVDTLGAIVRAVKPDGRLKLDRIGGFPWNMIEGENCTV
                     HVASTGQKVSGTILIHQTSCHVYKDAGTAERTQDNMEVRLDVKVSNEKETRALGIEVG
                     DFISFDPRTVVTDTGFIKSRHLDDKVSAAILLNLLRIYKKEKIELPVTTHFAFSVFEE
                     VGHGANSNIPAQVVEYLAVDMGAMGDDQQTDEYTVSICVKDASGPYHYDFRQHLVALA
                     KEQDIPFKLDIYPFYGSDASAAMSAGAEVKHALLGAGIESSHSYERTHIDSVVATERM
                     VDAYLRSNLVD"
     gene            complement(5216..6541)
                     /gene="brnQ"
                     /locus_tag="VQ862_000949"
     CDS             complement(5216..6541)
                     /gene="brnQ"
                     /locus_tag="VQ862_000949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006152071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HET3115315.1"
                     /translation="MAKKGTLTGLLLFGIFFGAGNLIFPPSLGALSGEHFLPAIAGFV
                     FSGVGIAVLTLIIGTLNPKGYIYEISTKIAPWFATLYLSVLYLSIGPFFATPRTATTA
                     YEVGISPLLSDANKGLGLIVFTVLYFAAAYLISLNPSKILDRIGRILTPVFAILIVIL
                     VVLGAIKYGGTSPQAASAAYQASAFGTGFLEGYNTLDALASVAFSVIAVQTLKQLGFS
                     SKKEYISTIWVIGIVVALAFSALYIGLGFLGNHFPVPAEAMKGGTPGVYILSQATQEI
                     FGSTAQLFLAAMVTVTCFTTTVGLIVSTAEFFNERFPQISYKVYATAFTLIGFAIANL
                     GLDAIIKYSIPVLVILYPITIAIVMIVIVNKFVALSKPGMQLTIAVVTVIAIASVLGS
                     SFKVEFLANLVSVLPFAKASLPWLVPAIVGILLSLVLPNKQESDVFEME"
     gene            complement(6712..6804)
                     /locus_tag="VQ862_000950"
     CDS             complement(6712..6804)
                     /locus_tag="VQ862_000950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HET3115316.1"
                     /translation="MRSARACQFLLEQGYNVINVQGGMLAFEEL"
     gene            complement(6847..6999)
                     /locus_tag="VQ862_000951"
     CDS             complement(6847..6999)
                     /locus_tag="VQ862_000951"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HET3115317.1"
                     /translation="MKEIAFDAFYQLYQNDQLSLVDVREVDEFAALHLECAHNLPLSQ
                     LADSYD"
     gene            complement(7159..7737)
                     /locus_tag="VQ862_000952"
     CDS             complement(7159..7737)
                     /locus_tag="VQ862_000952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase family protein"
                     /protein_id="HET3115318.1"
                     /translation="MSQIERIKQAIMADSQNASYTERGIEPLFAAPKTARINIIGQAP
                     GLKTQEAGLYWKDKSGDRLRDWLGVDEDTFYNSGYFAVLPMDFYFPGHGKSGDLPPRT
                     GFAEKWHPQLLQELPDIQLTLLIGQYAQAYYLQEKISGKVTERVKHYKDYLPAYFPLV
                     HPSPRNQIWMAKNPWFEAEVVPDLKKRIKTIL"
     gene            complement(7791..9191)
                     /gene="pepV"
                     /locus_tag="VQ862_000953"
     CDS             complement(7791..9191)
                     /gene="pepV"
                     /locus_tag="VQ862_000953"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000125034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase PepV"
                     /protein_id="HET3115319.1"
                     /translation="MTAIDFTAEVEKRKEDLLADLFSLLEINSERDDSKADAQHPFGP
                     GPVKALEKFLEIADRDGYPTKNVDNYAGHFEFGDGEEVLGIFAHMDVVPAGSGWDTDP
                     YTPTIKDGRLYARGASDDKGPTTACYYGLKIIKELGLPTSKKVRFIVGTDEESGWADM
                     DYYFEHVGLAKPDFGFSPDAEFPIINGEKGNITEYLHFAGENTGAARLHSFTGGLREN
                     MVPESATAVVSGDLADLQAKLDAFVAEHKLRGELQEEAGKYKVTIIGKSAHGAMPASG
                     VNGATYLALFLSQFGFAGPAKDYLDIAGKILLNDHEGENLKIAHVDEKMGALSMNAGV
                     FRFDETSADNTIALNIRYPKGTSPEQIKSILENLPVVSVSLSEHGHTPHYVPMEDPLV
                     QTLLNIYEKQTGLKGHEQVIGGGTFGRLLERGVAYGAMFPDSIDTMHQANEFIALDDL
                     FRAAAIYAEAIYELIK"
     gene            complement(9204..9809)
                     /locus_tag="VQ862_000954"
     CDS             complement(9204..9809)
                     /locus_tag="VQ862_000954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002924506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HET3115320.1"
                     /translation="MKFLELNKKRHATKHFTDKPVDPKDVRTAIEIATLAPSAHNSQP
                     WKFVVVREKNAELAKLAYGSNFEQVSSAPVTIALFTDTDLAKRARKIARVGGANNFSE
                     EQLQYFMKNLPAEFARYNEQQVSDYLALNAGLVAMNLVLALTDQGIGSNIILGFDKSK
                     VNEVLEIEDRFRPELLITVGYTDDKLEPSYRLPVDEIIEKR"
     gene            9980..10780
                     /locus_tag="VQ862_000955"
     CDS             9980..10780
                     /locus_tag="VQ862_000955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000714621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HET3115321.1"
                     /translation="MKKFSLLLAILPFLVACGNQATPKETSAQKTIVLATAGDVPPFD
                     YEDKGNLTGFDIEVLKAVDEKLSDYEIQFQRTAWESIFPGLDSGHYQAAANNLSYTKE
                     RAEKYLYSLPISNNPLVLVSNKKNPLTSLDQIAGKTTQEDTGTSNAQFINNWNQKHTD
                     NPATINFSGEDIGKRILDLANGEFDFLVFDKVSVQKIIKDRGLDLSVVDLPSADSPSN
                     YIIFSSDQKEFKEQFDKALKELYQDGTLEKLSNTYLGGSYLPDQSQLQ"
     gene            complement(10962..11759)
                     /locus_tag="VQ862_000956"
     CDS             complement(10962..11759)
                     /locus_tag="VQ862_000956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001015777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase family protein"
                     /protein_id="HET3115322.1"
                     /translation="MNHKIAILSDVHGNATALEAVIADAKNQGASEYWLLGDIFLPGP
                     GANDLVALLKDLPITASVRGNWDDRVLEALDGQYGLEDPQEVQLLRMTQYLMERMDPA
                     TIVWLRSLPLLEKKEIDGLRFSISHNLPDKNYGGDLLDAETDVAVYGHVHKQLLRYGS
                     QGQQIINPGSIGMPYFNWEALKNHRAQYAVIEVEDGELLNIQFRKVAYDYEAELELAK
                     SKGLPFIEMYEELRRDDNYQGHNLELLASLIEKHGYVEDVKNFFDFL"
     gene            complement(11791..13593)
                     /gene="uvrC"
                     /locus_tag="VQ862_000957"
     CDS             complement(11791..13593)
                     /gene="uvrC"
                     /locus_tag="VQ862_000957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001061148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrC"
                     /protein_id="HET3115323.1"
                     /translation="MNNLIKSKLELLPTSPGCYIHKDKNGTIIYVGKAKNLRNRVRSY
                     FRGSHDTKTEALVSEIVDFEFIVTESNIEALLLEINLIKENKPKYNIMLKDDKSYPFI
                     KITNERYPRLIITRQVKKDGGLYFGPYPDVGAANEIKRLLDRIFPFRKCTNPPSKVCF
                     YYHIGQCMAHTICKKDEAYFKSMAQEVSDFLKGQDDKIIDDLKSKMAVAAQSMEFERA
                     AEYRDLIQAIGTLRTKQRVMAKDLQNRDVFGYYVDKGWMCVQVFFVRQGKLIERDVNL
                     FPYFNDPDEDFLTYVGQFYQEKSHLVPNEVLIPQDIDEEAVKALVDSKILKPQRGEKK
                     QLVNLAIKNARVSLEQKFNLLEKSVEKTQGAIENLGRLLQIPTPVRIESFDNSNIMGT
                     SPVSAMVVFVNGKPSKKDYRKYKIKTVVGPDDYASMREVIRRRYGRVQREALTPPDLI
                     VIDGGQGQVNIAKQVIQEELGLDIPIAGLQKNDKHQTHELLFGDPLEVVDLSRNSQEF
                     FLLQRIQDEVHRFAITFHRQLRSKNSFSSQLDGIDGLGPKRKQNLMRHFKSLTKIKEA
                     SVDEIVEVGVPRVVAEAVQRKLNPQGEALPQVAE"
     gene            complement(13632..14333)
                     /locus_tag="VQ862_000958"
     CDS             complement(13632..14333)
                     /locus_tag="VQ862_000958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001267193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="matrixin family metalloprotease"
                     /protein_id="HET3115324.1"
                     /translation="MRWLFRLIGAFFSFVWRLFWRLVWIVVLLCVLAFGLLWYLNGDF
                     QGALKQAERSVKIGQQSIDQWEKTGQLPKLSQTDSHQHSEGRWAQASARIYLDPQMDS
                     RFQEAYLEAIQNWNQTGAFNFELVTESSKADITATEMNDGGTPVAGEAESQTNLLTGQ
                     FLSVTVRLNHYYLSNPYYGYSYERLVHTAEHELGHAIGLDHTDEKSVMQPAGSFYGIQ
                     EEDVANLRKIYETSE"
     gene            complement(14412..15644)
                     /gene="murN"
                     /locus_tag="VQ862_000959"
     CDS             complement(14412..15644)
                     /gene="murN"
                     /locus_tag="VQ862_000959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001229509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan bridge formation alanyltransferase
                     MurN"
                     /protein_id="HET3115325.1"
                     /translation="MALTTLTKEEFQTYSDQVSSRSFMQSVQMGDLLEKRGARIVYLA
                     LKQEGEIQVAALVYSLPMLGGLHMELNSGPIYTQQDALPVFYAELKEYAKQNGVLELL
                     VKPYETYQTFDSQGNPIDAEKKSIIQGLTDLGYQFDGLTTGYPGGEPDWLYYKDLTEL
                     TEKSLLKSFSKKGKPLVKKAETFGIRLKKLKREELSIFKNITKETSERREYSDKSLEY
                     YEHFYDTFGEQAEFLIASLNFSDYMSKLQGEQSKLEENLDKLRLDLSKNPHSEKKQNQ
                     LREYSSQFETFEVRKAEARDLIEKYGEEDIVLAGSLFVYMPQETTYLFSGSYTEFNKF
                     YAPALLQKYVMLESIKRGIPKYNFLGIQGIFDGSDGVLRFKQNFNGYIVRKAGTFRYH
                     PSPLKYKAIQLLKKIVGR"
     gene            complement(15649..16869)
                     /gene="murM"
                     /locus_tag="VQ862_000960"
     CDS             complement(15649..16869)
                     /gene="murM"
                     /locus_tag="VQ862_000960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001819885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan bridge formation alanyltransferase
                     MurM"
                     /protein_id="HET3115326.1"
                     /translation="MYRYQIGIPTLEYDQFVKEHELANVLQSSAWEEVKSNWQHEKFG
                     VYREEKLLATASILIRTLPLGYKMFYIPRGPILDYGDKELLNFVIQSIKSYARSKRAV
                     FVTFDPSICLSQSLINQEKTEFPENLAIIDSLQQMGVRWSGKTEEMGDTIQPRIQAKI
                     YKENFEEDKLSKSTKQAIRTARNKGLEIQYGGLELLDSFSELMKKTEKRKEIHLRNEA
                     YYKKLLDNFKDKAYITLATLDVSKRSQELEEQLAKNRALEETFTESTRISKVEAQKKE
                     KERLLEELTFLQEYIDVGQARVPLAATLSLEFGTTSVNIYAGMDDDFKRYNAPILTWY
                     ETARYAFERGMVWQNLGGVENSLNGGLYHFKEKFNPTIEEYLGEFTMPTHPLYPLLRL
                     ALDFRKTLRKKHRK"
     gene            complement(16981..17760)
                     /locus_tag="VQ862_000961"
     CDS             complement(16981..17760)
                     /locus_tag="VQ862_000961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase family protein"
                     /protein_id="HET3115327.1"
                     /translation="MAVMKIEYYSQVLDMEWGVNVLYPDANRVEEPECEDIPVLYLLH
                     GMSGNHNSWLKRTNVERLLRGTNLIVVMPNTSNGWYTDTQYGFDYYTALAEELPQVLK
                     RFFPNMTSKREKTFIAGLSMGGYGCFKLALATNRFSHAASFSGALSFQNFSPESQNLG
                     SPAYWRGVFGEIKDWTTSPYSLESLAKKSDKKTKLWAWCGEQDFLYEANNLAVKNLKK
                     LGFDVTYSHSAGTHEWYYWEKQLEVFLTTLPIDFKLEERLT"
     gene            complement(17829..19490)
                     /locus_tag="VQ862_000962"
     CDS             complement(17829..19490)
                     /locus_tag="VQ862_000962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HET3115328.1"
                     /translation="MSNISLTTLGGVRENGKNMYIAEIGESIFVLNVGLKYPENEQLG
                     VDVVIPNMDYLFENSDRIAGVFLTHGHADAIGALPYLLAEAKVPVFGSELTIELAKLF
                     VKGNDAVKKFNDFHVIDENTEIDFGGTVVSFFPTTYSVPESLGIVLKTSEGSIVYTGD
                     FKFDQTASESYATDFARLAEIGRDGVLALLSDSANADSNIQVASESEVRDEITQTIAD
                     WEGRIIVAAVSSNLSRIQQIFDAADKTGRRIVLTGFDIENIVRTAIRLKKLSLANEIL
                     LIKPKDMSRFEDHELIILETGRMGEPINGLRKMSIGRHRYVEIKDGDLVYIATAPSIA
                     KEAFVARVENMIYQAGGVVKLITQSLHVSGHGNVRDLQLMINLLQPKYLFPVQGEYRE
                     LDAHAKAAMAVGMLPEHIFIPKKGTTMAYENGDFVPAGSVSAGDILIDGNAIGDVGNV
                     VLRDRKVLSEDGIFIVAITVNRREKKIVARARVHTRGFVYLKKSRDILHESSELINQT
                     VEEYLQGDDFDWADLKGKVRDNLTKYLFDQTKRRPAILPVVMEAK"
     gene            complement(19665..21887)
                     /gene="recJ"
                     /locus_tag="VQ862_000963"
     CDS             complement(19665..21887)
                     /gene="recJ"
                     /locus_tag="VQ862_000963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001832038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded-DNA-specific exonuclease RecJ"
                     /protein_id="HET3115329.1"
                     /translation="MITPTYEWQFALQVEDADFTKIAKKAGLGPEVARLLFERGIQDQ
                     ESLKKFLEPSLEDLHDAYLLHDMDKAVERIRQAIEEGENILVYGDYDADGMTSASIVK
                     ESLEQLGAECRVYLPNRFTDGYGPNASVYKYFIEQEGISLIVTVDNGVAGHEAIALAQ
                     SMGVDVIVTDHHSMPETLPDAYAIVHPEHPDADYPFKYLAGCGVAFKLACALLEEVQV
                     ELLDLVAIGTIADMVSLTDENRILVQYGLEMLGHTQRIGLQEMLDMAGIAANEVTEET
                     VGFQIAPRLNALGRLDDPNPAIDLLTGFDDEEAHEIALMIHQKNEERKEIVQSIYEEA
                     KTMVDPEKKVQVLAKEGWNPGVLGIVAGRLLEELGQTVIVLNIEDGRAKGSARSVEAV
                     DIFEALDPHRDLFIAFGGHAGAAGMTLEVEQLSDLSQVLEDYVREKGADAGGKNKLNL
                     DEELDLEALSLETVKSFERLAPFGMDNQKPIFYIKNFQVESARTMGAGNAHLKLKISK
                     GEASFEVVAFGQGRWATEFSQTKNLELAVKLSVNQWNGQTALQLMMVDARVEGVQLFN
                     IRGKNAVLPEGVPVLDFPGELPNLAASEAIVVKNIPEDITQLKTIFQEQHFSAVYFKN
                     DIDKAYYLTGYGTRDQFAKLYKTIYQFPEFDIRYKLKDLAAYLNIQQILLVKMIQVFE
                     ELGFVTIKDGVMTVNKEAPKREIGESQIYQNLKQTVKDQEMMALGTVQEIYDFLMEKE
                     "
     gene            22164..22922
                     /locus_tag="VQ862_000964"
     CDS             22164..22922
                     /locus_tag="VQ862_000964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HET3115330.1"
                     /translation="MALVEFKNVEKYYGDYHALRNINLRFEKGQVVVLLGPSGSGKST
                     LIRTINGLEAVDKGSLLVNGHQVAGASQKDLVPLRKEVGMVFQHFNLYPHKTVLENVT
                     LAPIKVLGIDKKEAEKTAQKYLEFVNMWDKKDSYPAILSGGQKQRIAIARGLAMHPEL
                     LLFDEPTSALDPETIGDVLAVMQKLAHDGMNMIIVTHEMGFAREVADRIIFMADGEVL
                     LDTTDVDNFFDNPSKPRAQQFLSKIINHESDKVK"
     gene            22933..23727
                     /locus_tag="VQ862_000965"
     CDS             22933..23727
                     /locus_tag="VQ862_000965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000726191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HET3115331.1"
                     /translation="MKKKFFLSALLISLFGLAAAKPVQADTSIADIQKRGELVVGVKQ
                     DVPNFGYKDPKTGTYSGIETDLAKMVADELKVKIRYVPVTAQTRGPLLDNEQVDMDIA
                     TFTITDERKKLYNFTSPYYTDASGFLVNKSAKIKKIEDLNGKTIGVAQGSITQRLITE
                     LGKKKGLKFKFVELGSYPELITSLHAHRIDAFSVDHSILSGYTSKRTALLDDSFKPSD
                     YSIVTKKSNTELNDYLDNLVTKWSKDGSLQKLYDRYKLKPSSHTAD"
     gene            23740..24417
                     /locus_tag="VQ862_000966"
     CDS             23740..24417
                     /locus_tag="VQ862_000966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HET3115332.1"
                     /translation="MTDLSSWTAYFQDFGQFFNGFLFTLALAIGSFILAMVLGIFFGA
                     MSTSKRPILRILARIFVEFYQNTPLLVQFVIVFYGLPLISDHIIMIPIYWTAVLCVGL
                     YHGAYIAEVIRSGIQSIPSGQMEAALSQGFTYISAMRLIILPQAFRIILPPLTNQIVN
                     LIKNTSTVAIISGVDLMFVTKSWSALNGNYIPAFLGAALLYFALCFPVAQFGRKMEQA
                     NKKAYSL"
     gene            24427..25086
                     /locus_tag="VQ862_000967"
     CDS             24427..25086
                     /locus_tag="VQ862_000967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000443867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HET3115333.1"
                     /translation="MESILEILTPDNLVFIFKGFGLTLYISLIAIILSTIIGTVLAVM
                     RNGKNPILRIISSIYIEFVRNVPNLLWIFTIFLVFKMKSTPAGITAFTLFTSAALAEI
                     IRGGLNAVDKGQYEAGMSQGFTSAQILYYIILPQAIRKMLPAIISQFVTVIKDTSLLY
                     SVIALQELFGASQILMGRYFEPEQVFSLYILIALIYFSFNLAISSLSHMLAKRWQQAA
                     E"
     gene            25323..26447
                     /locus_tag="VQ862_000968"
     CDS             25323..26447
                     /locus_tag="VQ862_000968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferric reductase-like transmembrane
                     domain-containing protein"
                     /protein_id="HET3115334.1"
                     /translation="MEFSMKSVKGLLFIIASFILTLLTWMNTSPQFMIPGLALTSLSL
                     TFILATRLPLLESWFHGLEKVYTVHKFTAFLSIILLIFHNFSMGGLWGSRLAAQFGNL
                     AIYIFASIILVAYLGKYIQYEAWRWIHRLVYLAYILGLFHIYMIMGNRLLTFNLLSFL
                     VGSYALLGLLAGFYIIFLYQKISFPYLGKITHLKRLNHDTREIQIHLSRPFNYQSGQF
                     AFLKIFQEGFESAPHPFSISGGHGQTLYFTVKNSGDHTNNIYDNLQAGSKVTLDRAYG
                     HMIIEEGRENQVWIAGGIGITPFISYIREHPILDKQVHFYYNFRGDENAVYLDLLRNY
                     AQKNPNFELHLIDSTKDGYLNFEQKKCPNMQPSICVVLFL"
     gene            complement(26845..27726)
                     /locus_tag="VQ862_000969"
     CDS             complement(26845..27726)
                     /locus_tag="VQ862_000969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-bisphosphate aldolase"
                     /protein_id="HET3115335.1"
                     /translation="MAIVSAEKFVQAARDNGYAVGGFNTNNLEWTQAILRAAEAKKAP
                     VLIQTSMGAAKYMGGYKVARNLIANLVESMGITVPVAIHLDHGHYEDALECIEVGYTS
                     IMFDGSHLPVEENLKLAKEVVEKAHAKGISVEAEVGTIGGEEDGIIGKGELAPIEDAK
                     AMVETGIDFLAAGIGNIHGPYPVNWEGLDLDHLQKLTEALPGFPIVLHGGSGIPDEQI
                     QAAIKLGVAKVNVNTECQIAFANATRKFARDYEANEAEYDKKKLFDPRKFLADGVKAI
                     QASVEERIDVFGSEGKA"
     gene            complement(27867..29195)
                     /gene="vncS"
                     /locus_tag="VQ862_000970"
     CDS             complement(27867..29195)
                     /gene="vncS"
                     /locus_tag="VQ862_000970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase VncS"
                     /protein_id="HET3115336.1"
                     /translation="MKRTGLFTKIFIYTFSIFSVLVICLHLAIYFLFPSTYLSHRQET
                     IGQKATAIAQSLEGKDRQSIEQVLDLYSQTSDIKGTVKGEMTEDKLEVKDSLPLDTDR
                     QTTSLFIEEREVKTQDGGTMILQFLASMDLQKEAEQISLQFLPYTLLASFLISLLVAY
                     IYARTIVAPILEIKRVTRRMMDLDSQVRLRVDSKDEIGNLKEQINSLYQHLLTVIADL
                     HEKNEAILQLEKMKVEFLRGASHELKTPLASLKILIENMRENIGRYKNRDQYLGVALG
                     IVDELNHHVLQILSLSSVQELRDDRETIDLLQMTQNLVKDYALLAKERELQIDNSLTH
                     QQAYLNPSVMKLILSNLISNAIKHSVPGGLVRIGEREGELFIENSCSSEEQEKLAQSF
                     SDNASRKVKGSGMGLFVVKSLLEHEKLAYRFEMEENRLTFFIDFPKVVQD"
     gene            complement(29192..29848)
                     /gene="vncR"
                     /locus_tag="VQ862_000971"
     CDS             complement(29192..29848)
                     /gene="vncR"
                     /locus_tag="VQ862_000971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000697958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor VncR"
                     /protein_id="HET3115337.1"
                     /translation="MKILIVEDEEMIREGVSDYLTDCGYETIEAADGQEALEQFSSYE
                     VALVLLDIQMPKLNGLEVLAEIRKTSQVPVLMLTAFQDEEYKMSAFASLADGYLEKPF
                     SLSLLKVRVDAIFKRYYDTGRIFSYKDTKVDFESYSASLAGQEVPINAKELEILDYLV
                     KNEGRALTRSQIIDAVWKATDEVPFDRVIDVYIKELRKKLDLDCILTVRNVGYKLERK
                     "
     gene            complement(29897..29980)
                     /gene="pep27"
                     /locus_tag="VQ862_000972"
     CDS             complement(29897..29980)
                     /gene="pep27"
                     /locus_tag="VQ862_000972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_198523890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative autolysis signal peptide Pep27"
                     /protein_id="HET3115338.1"
                     /translation="MRKEFHNVLSSGQLLTDKRPARDYNRK"
     gene            complement(30161..31540)
                     /gene="vex3"
                     /locus_tag="VQ862_000973"
     CDS             complement(30161..31540)
                     /gene="vex3"
                     /locus_tag="VQ862_000973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit Vex3"
                     /protein_id="HET3115339.1"
                     /translation="MLHNAFAYVTRKFFKSIVIFLIILLMASLSLVGLSIKGATAKAS
                     QETFKNITNSFSMQINRRVNQGTPRGAGNIKGEDIKKITENKAIESYVKRINAIGDLT
                     GYDLIETPETKKNLTADRAKRFGSSLMITGVNDSSKEDKFVSGSYKLVEGEHLTNDDK
                     DKILLHKDLAAKHGWKVGDKVKLDSNIYDADNEKGAKETVEVTIKGLFDGHNKSAVTY
                     SQELYENTAITDIHTAAKLYGYTEDTAIYGDATFFVTADKNLDDVMKELNGISGINWK
                     SYTLVKSSSNYPALEQSISGMYKMANLLFWGSLSFSVLLLALLLSLWINARRKEVGIL
                     LSIGLKQASILGQFITESILIAIPALVSAYFLANYTARAIGNTVLANVTSGVAKQASK
                     AAQASNLGGGAEVDGFSKTLSSLDISIQTSDFIIIFVLALVLVVLVMALASSNLLRKQ
                     PKELLLDGE"
     gene            complement(31592..32239)
                     /gene="vex2"
                     /locus_tag="VQ862_000974"
     CDS             complement(31592..32239)
                     /gene="vex2"
                     /locus_tag="VQ862_000974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000173730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding subunit Vex2"
                     /protein_id="HET3115340.1"
                     /translation="MTLLQLQDVTYRYKNTAEAVLYQINYNFEPGKFYSIIGESGAGK
                     STLLSLLAGLDSPVEGSILFQGEDIRKKGYSYHRMHHISLVFQNYNLIDYLSPLENIQ
                     LVNKKASKNTLLELGLDESQIKRNVLQLSGGQQQRVAIARSLVSEAPVILADEPTGNL
                     DPKTAGDIVELLKSLAQKTGKCVIVVTHSKEVAQASDITLELKDKKLTETRNTSK"
     gene            complement(32252..33529)
                     /locus_tag="VQ862_000975"
     CDS             complement(32252..33529)
                     /locus_tag="VQ862_000975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001068247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET3115341.1"
                     /translation="MNPIQRSWAYVSRKRLRSFILFLILLVLLAGISACLTLMKSNKT
                     VESNLYKSLNTSFSIKKIENGQTFKLSDLASVSKIKGLENVSPELETVAKLKDKEAVT
                     GEQSVERDDLSAADNNLVSLTALEDSSKDVTFTSSAFNLKEGRHLQKGDSKKILIHEE
                     LAKKNGLSLHDKIGLDAGQSESGKGQTVEFEIIGIFSGKKQEKFTGLSSDFSENQVFT
                     DYESSQTLLGNSEAQVSAARFYVENPKEMDGLMKQVENLALENQGYQVEKENKAFEQI
                     KDSVATFQTFLTIFLYGMLIAGAGALILVLSLWLRERVYEVGILLALGKGKSSIFLQF
                     CLEVVLVSLGALLPAFVAGNGITTYLLQTLLASGDQVSLQDTLAKASSLSTSILSFAE
                     SYVFLVLLSCLSVALCFLFLFRKSPKEILSSIS"
BASE COUNT         9511 a         7704 c         6258 g        10173 t
ORIGIN      
        1 tacatctctt cttctaaaac attgttagaa atcgatttgg ctgccctgat cgattcgtcc
       61 tactcttatt tcattttact ataattgata gtggtcgccc cagccagata ccttatccgc
      121 tatataggcc ttattatcac gttcctgttc gtagagccac gatttcgcta tcccttcctc
      181 tgacgattct tatttccagc gtcagactta aaacggtcta tccccagacc gttttaatcc
      241 gctacctcac gatagtcaga cttgggaatc gctattgggt tcaccagtag taggtgccca
      301 ccgaggattt acacctcaga tatacgacat gcccgtcgta tatcaaaaaa agttgagaca
      361 tagcgtcttc aactttttta cattacttta actactgatt aaagtgagtt tacgtcaact
      421 ttgataccaa caccttgagt agttgtgata gtcaagtttg ttacgtaagt tcctttagct
      481 gtagctggtt ttgctttttg gattgtttcg ttgaaagctt taaagttttc aaccaatttt
      541 tcagcttcaa atgatacttt accgatgatt gcttgaacgt tacctgcacg gtcagcacgg
      601 taagtgattt taccaccttt agactcttca actgctttag caacatccat tgttacagta
      661 ccagttttag ggtttggcat caagttacgt ggtccaagga cacgtccaag acgtccaaca
      721 agagccatca tatcaggtgt agcgataact acgtcgaaat ccaaccaacc gtcgttgatt
      781 ttagcaacaa ggtcatcttc accaacaaag tctgcaccag cagcttttgc ttcttcagct
      841 tttgcaccac gtgcgaaaac aagaacacgt gaagttttac cagtaccgtt tggcaatacc
      901 attgctccac ggatttgttg gtcagctttt ttaacgtcga tgttcaagtt gtaagcaact
      961 tctacagttg cgtcaaattt tgcaaagtta gtttcttttg caagtgctac agcttcttct
     1021 acgctgtatg cttttgtgct gtcgattttc tcaagagcag cacgaagttg tttgcttttt
     1081 ttagccattt tctattctcc ttgtaagtgg ttcaatcgat tttcatctcc cacgtcactt
     1141 ctcgaaatga tgaagtcttg cgggttttca gtctactatt tttctcttcc tacggcctta
     1201 agctcccttg ctgtacccaa gtacaagcct cagtcacttg cctagtatga aaagcaacta
     1261 atagactgct gtgagatttt ctactgtgtt attgattagt caacaacagt gaatcccata
     1321 gaacgagcag taccttcgat catacgcatt gcagactcta cgtttgctgc gttcaaatct
     1381 ggcatcttag tttctgcaat ttcttgtact tgtgcacgag taactgtagc aactttagtt
     1441 ttattaggtg tacctgatcc tttttcaaca cctgcagctt ttttcaaaag aacagcagct
     1501 ggtggtgttt tcgtaacgaa agtaaatgat ttatcttcgt aaactgagat aacaactgga
     1561 atgatcatac cagcttggtc agctgtacga gcgttgaact cttttgtgaa tcccatgatg
     1621 ttgataccag cttgaccaag agcaggtcca accggtggag ctggtgtagc tttaccagca
     1681 gggatttgca attttacaag tttttcgact tttttagcca tttttaaatc ctcctttgtg
     1741 gttttggcgg taattagaga tttttacctc ccacaagtat gtttttcaca tacccatcca
     1801 ttatacacta tttatctgga attgcaagag aaaagtttat tttttatact caatgaaaat
     1861 caaagagcaa actaggaagc tagctgtagg ctgctcaaag tacagctttg agattgcaga
     1921 taaaactgac gaagtcagct caaaacactg ttttgaggtt gtgaatagaa ccgacgcagt
     1981 cagtaggtaa ggcgacgctg acgtggtttg aagagatttt cgaagagtat taatcgacgt
     2041 agtctccgcc ttcaaagcca tagtattctt ccaaactgag accacttgca gcaatttctt
     2101 tagcttcttt tcctacataa cgcaggtgcc attcctcagc catatagcct gtttcctttt
     2161 ccttgccttt gagataacgg acaacaaagc cataatcagc tgcatgatcc aagagccatt
     2221 gggctgcttt ttcttctgtc accaaatcac catcagtccc aatcacatca aaggccaagc
     2281 ctgtctggtg ttcgctatag ccaggacggg cagagtaacg gtcagctgct gcctttccat
     2341 cttggttgac ataatcttga tagagcttgg tctgagtttc ataacttcta aaaccactgt
     2401 aatgatcact aatagggaaa cctgcctctt gcatcgcttt gatgagtttg accaactcag
     2461 ccttggctgt tggattttcc cccggattat agtctttcga caaaggataa tgtttattgg
     2521 ctacgatgat ttcgtcgtat tttccttgga tgctgtagta atcaccttta ttgaccactt
     2581 ctgctttttt ctgggcagcc ccttgagact tactgccgac tgtcccatca gctttggctg
     2641 tctgttctgt cttagctgtg ccatcttcat tttttgcttt ttcttgtgaa caagctgcta
     2701 gactcaaggc tagcaaggct gtcacgacaa ggtatctttt cttcatttct actcctttat
     2761 ttctaatagt ttatctactt ctgatgataa acgtttgact aatcttttaa tagacttcct
     2821 gcaaaactag aatcctagtt catgattgat aataccagca atcaaattca ttcgtaatcc
     2881 gaagcgttta cgatgatttc gataggttgt tgaaaacatt ttaaacgttt ttactttggc
     2941 aaggatgttc tcaaccttgc ttctatcctt agatagcgca tggttatagg ctttatcttc
     3001 agctattagc ggcttgagtt tgctggattt acgtggaatt tgtgcttgag gatatatctt
     3061 catgagccct tgataatcac tgtcagccaa gattttacca gcttgtccga tatttctgcg
     3121 actcattttg aacaacttca tatcatgaca atagttcaca gtgatatcca aagaaacaat
     3181 tctcccttga cttgtgacaa tcgcttgagc cttcatagcg tggcatttct ttttaccaga
     3241 ataattcgct aattcttttt ttagggcgat tgatttttac ttccgtcgca tcaatcatta
     3301 ccgtgtcctc agaactgaga ggagttcttg aaatcgtaaa accactttga acaagagtta
     3361 cttcaaccca ttggctccga cggagtaagt tgctttcgtg gataccaaaa tcagccgcaa
     3421 tttcttcata agttcgatat tctcgcacat attgaagagt ggccataaga aggtcttcta
     3481 ggcttaattt aggttttcgt ccaccttttg cgtgtttaag ttgataagct gtttttaata
     3541 cagctaacat ctcttcaaaa gtggtacgct gaacaccaac aagacgctta aatcgtgcat
     3601 cagttagttg tttacttgct tcatcattca tagaactact ataccatatt ttgtttcgca
     3661 ggaagtctga tctcatccgg ttttgcttga cgggtttctg cggtcatttc ttcaaaaggg
     3721 acccaccaga ctggcccacg tccattgaga ccgtgaccat tcatgtcacc tgttcgtcta
     3781 ggaaacagat gccaatgaag atgggcatcg ccatttccta gcagttcgat attcattttc
     3841 tcagcagcaa aggccttggc aactgcctct tggaccacac tcatttcttc tagaaaacgg
     3901 agtcttgtct cctttttcaa atggtgcaat tccgtgacat gttccttggc tagaaagaga
     3961 ctatagcctg caaaatactg atggtctcca atcacaagat agcctgtttc caactctttg
     4021 acaaagtagg gattttctcc cttcttgatg agctcaattc tctggcaaat aaggcacata
     4081 tcaatctact aaattgcttc taagataggc atcgaccatt cgttctgttg cgaccaccga
     4141 gtcaatatga gtgcgctcat aagaatgact agactcgata cccgcaccaa gaagggcatg
     4201 cttgacctct gcccctgcag acatagccgc tgaagcatcc gaaccataaa atggatagat
     4261 gtccagctta aaaggaatat cttgctcttt agccaaggca accaagtgtt gacggaagtc
     4321 atagtgataa ggacctgaag catccttgac acagatagat actgtgtact catctgtctg
     4381 ctggtcatct cccatagctc ccatatccac agccagatat tctactacct gagcaggaat
     4441 gttagaatta gcaccatgtc ctacttcttc aaaaactgaa aaagcaaaat gagttgttac
     4501 tggcaattca atcttctctt tcttataaat acgaagcagg ttgagcaaaa tcgctgcgct
     4561 gaccttatca tccaaatgac gagacttgat aaaacctgta tcagtcacaa cagttcgtgg
     4621 atcgaagctg ataaaatcac cgacctcaat cccaagagca cgagtttctt tttcattgct
     4681 tacttttaca tccaaacgca cttccatatt gtcctgcgtg cgttctgcag ttcctgcatc
     4741 cttgtagaca tggcaagaag tttggtggat gaggatggtt cctgatacct tttgacctgt
     4801 gctagccaca tgaacggtac agttttcacc ttcaatcatg ttccaaggaa aaccaccgat
     4861 acggtccaat ttaagacgac catctggttt gacagcacga acaatagcac ccagcgtgtc
     4921 cacatgggca gtcacatagc gatgttgctc atcattttga cctttgatgg tcacattgac
     4981 accacccttg gctgtgcgaa ctggctggta accaaaacct tctagagtct tgactaaata
     5041 attcgaaatt tcacgagtta agcccgttgg cgatgcgatg gctgtcagtt ctttgatata
     5101 ttctactgtt tgattcattt cttcacctct ttcgctacct attataacac atttatcatc
     5161 ggataaaaaa agaaaatcac tcctgtagac ttggctacaa aagtgattta agtgattatt
     5221 ccatttcaaa aacatcgctt tcttgcttgt ttggtagaac caatgagagc aagattccaa
     5281 caatggctgg caccaaccat gggagagatg ccttggcaaa aggaagaacg ctaacaagat
     5341 ttgcaagaaa ctcaacctta aacgagcttc ctagtacgct tgcaatggca ataactgtaa
     5401 ccacagcaat tgtcaactgc atacctggtt ttgaaagggc aacaaatttg ttgacaatga
     5461 caatcataac gatagcaatc gtgattgggt acaagataac cagtactgga attgagtact
     5521 tgataatcgc atcaagaccc aaattggcaa tagcaaatcc aatcaaggta aaggctgtcg
     5581 cataaacctt gtagctgatt tgtgggaagc gctcattaaa gaactcagct gttgacacaa
     5641 tcaaaccaac agtcgttgtg aagcaggtta cggtaaccat agctgcaagg aagagttgag
     5701 ctgttgagcc aaagatttct tgagtggctt gtgacaagat gtaaacacct ggtgttccac
     5761 ccttcatcgc ttcagctggt actgggaaat gatttccaag aaaacctaaa ccaatgtaaa
     5821 gagcgctgaa ggcaagggca acaacgatac caataaccca aatagttgaa atgtattctt
     5881 tcttacttga aaatccaagt tgtttcaagg tttgaactgc gattacgcta aaggccactg
     5941 aggcaagggc gtccaaggta ttgtaacctt ctaggaaacc tgtaccaaag gcagaagctt
     6001 gataagcagc tgaagcagct tgaggacttg ttccaccata tttgatagct cccagaacga
     6061 ccaagataac aatcaaaatt gcaaagactg gcgttaaaat acgtccaatg cggtctaaga
     6121 tttttgatgg attaagcgaa atcaaatagg ctgccgcaaa atacagaacc gtaaatacaa
     6181 tcaagccaag tcctttattt gcatccgaca aaagggggct aatccctact tcgtaagctg
     6241 ttgtagcagt acgtggggta gcaaagaatg gaccgattga caagtaaaga actgagaggt
     6301 aaagagtcgc aaaccaaggc gctatcttcg ttgaaatctc gtagatatat cctttaggat
     6361 ttagcgttcc aataataagg gtcaagacgg cgataccaac gcctgaaaag acaaaacctg
     6421 cgatggcagg aagaaaatgt tctccagata gagcacctag agaaggcgga aaaatcaagt
     6481 tccccgcacc aaaaaatatt ccaaacagga gcaaacctgt tagggtacct tttttagcca
     6541 taaaaatctc cttcatattt ataaaatact gacctagtat accacgatta ggagtctgaa
     6601 aaaagcatca cgaggcaaat attaaatgtt ttcaattttc ttaaaaataa gaattatcta
     6661 aaaataaaac tctcctaccc agtccacacc aagtaggaga aatgcaaaat tttaaagttc
     6721 ttcaaaggct aacatgccac cctggacatt gataacatta taaccttgtt ctaacaggaa
     6781 ttggcaagca cgcgccgatc tcattccaga tttgcaaata atataatgca agcgatcttt
     6841 gtccaattaa tcataactat cagccaattg actaagcggt aggttgtggg cacattctaa
     6901 atgaagagct gcaaactcat ccacttctct cacatccact agagaaagct ggtcgttttg
     6961 gtaaagctgg taaaatgcgt caaaggctat ttctttcatt ctttttcttc taatactctt
     7021 cgaaaatctc ttcaaaccac gtcagcgtcg ccttaccgtg cgtatgttac cgacttcgtc
     7081 agttttatct gcaacctcaa agctgtactt tgagcagcct acgactagct tcctagtttg
     7141 ctctttgatt ttcattgact ataaaatggt tttaattctt tttttcaaat ctggcactac
     7201 ttctgcctca aaccaaggat ttttggccat ccagatttga tttcgtggtg atgggtgaac
     7261 tagcggaaaa taggctggca gatagtcttt atagtgtttc accctctccg ttaccttccc
     7321 actgattttc tcctgtaaat agtaggcttg ggcatattgc ccaatcaaga gggttaactg
     7381 aatatcaggc aattcctgta agagctgcgg atgccatttt tctgcaaaac ctgtacgagg
     7441 cggaagatca cccgacttgc catgtcctgg aaagtagaaa tccataggca aaacagcaaa
     7501 ataacctgaa ttgtaaaagg tatcttcatc cacacctagc cagtcccgca agcggtcacc
     7561 acttttatct ttccagtaaa ggcctgcttc ttgagtttta agtcccggag cctgaccgat
     7621 gatattgatg cgagcagttt ttggcgctgc aaagagaggc tcaatgccac gctctgtata
     7681 gctggcattc tgtgaatccg ccatgatagc ctgtttgatt ctttcgattt gagacatcta
     7741 ctttccctcc aaaaagaagt ccaagcataa gatctcagac ttctatcgtt ttatttgatc
     7801 aattcgtaaa tagcttcggc ataaattgct gctgctcgga aaagatcatc caaggcgata
     7861 aattcattgg cttggtgcat ggtatcaatc gagtctggga acatagcacc gtaggcaact
     7921 ccgcgttcta gcaagcgacc aaaggttcca ccaccgatga cttgttcatg acctttaagg
     7981 ccagtttgtt tttcatagat attcaacaag gtttgcacaa gtggatcttc cattggcaca
     8041 tagtgaggcg tgtgaccgtg ttcagacagg ctaacagaaa caactggcaa gttttcaagg
     8101 attgacttga tttgttctgg acttgttcct tttggatagc ggatgttgag ggcaatggta
     8161 ttatcagcac ttgtttcatc gaagcggaag acgccggcat tcatagaaag agcacccatc
     8221 ttttcatcca catgagcaat cttaagattt tcaccctcat gatcgttcaa gagaatttta
     8281 cctgcgatgt caaggtagtc tttggctgga ccagcaaagc caaactggct gaggaagagg
     8341 gcaaggtaag ttgcgccatt gacacctgaa gcaggcatag caccgtgggc tgatttacca
     8401 atgatcgtca ccttgtattt gccagcttct tcttggagtt ctcctctaag tttgtgttct
     8461 gcaacaaagg catctagttt agcttgcaag tcagccaaat cacctgaaac gactgctgtt
     8521 gctgattctg gtaccatatt ttcacgtaaa ccacctgtaa agctgtgaag acgggcagca
     8581 cctgtatttt ctcctgcaaa gtggaggtat tccgtgatat ttcctttttc accattgatg
     8641 attggaaatt cagcatctgg agagaaaccg aaatctggtt tggcaagtcc tacgtgctca
     8701 aagtagtagt ccatgtctgc ccagcctgat tcttcgtctg ttccaacgat gaagcgaact
     8761 ttcttagaag ttggaagacc caattctttg atgattttca aaccatagta acaagctgtt
     8821 gtaggaccct tatcgtccga agccccgcgc gcataaaggc gaccatcttt gatagttggt
     8881 gtgtaaggat ctgtgtccca accgctacca gcaggcacca catccatatg ggcaaagatt
     8941 ccgagaactt cttctccatc accaaactca aaatgtcctg cgtagttatc gacattctta
     9001 gttgggtagc catcgcggtc tgcgatttca aggaatttct ccaaggcttt tactggacca
     9061 ggtccaaatg gatgctgggc atcagccttg ctatcatcac gttctgagtt gatttccaaa
     9121 aggctaaaca agtcagccaa gaggtcttct ttgcgttttt ctacttctgc tgtaaaatca
     9181 attgctgtca ttttttcttc tttctatctt ttctcgatga tttcatctac tggcaagcgg
     9241 tagcttggtt ccaatttgtc gtctgtgtaa cccactgtga tcaagagttc tgggcggaaa
     9301 cggtcttcga tttccaaaac ttcattaact tttgatttgt caaaaccaag gataatattg
     9361 gaaccaattc cttggtctgt aagagcgaga accaagttca tagcaaccaa acctgcattg
     9421 agtgctaggt agtcgctgac ttgttgttca ttgtagcgtg caaattcagc tggcaaattt
     9481 ttcatgaagt attgaagttg ctcttcagaa aagttattag caccaccaac acgggcaatc
     9541 ttacgagcac gtttggctaa gtccgtatct gtaaacaagg caatggttac aggcgctgat
     9601 gatacctgtt caaaattgga accataagct aactttgcca gttcagcatt tttctcacgt
     9661 accaccacaa atttccaagg ctggctgttg tgggcgcttg gcgccaaggt tgcaatttcg
     9721 atagccgtac gcacatcttt tggatcaaca ggcttatcag taaaatgctt agtcgcatga
     9781 cgttttttat ttaattcaag aaatttcata atcgatttcc ttttctaatt ctactgcttc
     9841 cattctacca taatttgaaa gagcttgcag ggatttttca tgattaagtt tttctatcac
     9901 agacataaaa gatatatatt ggtttatcag gaacatttct gataaactag caagtacttt
     9961 acatttgaat ggagacagta tgaaaaaatt tagcctatta ctagctatcc taccattttt
    10021 ggttgcctgt gggaatcaag ctacacccaa agagactagc gctcaaaaga caatcgtcct
    10081 tgctacagct ggcgacgtgc caccgtttga ctacgaagac aagggcaatc tgacaggctt
    10141 cgatatcgaa gttttaaagg cagtagatga aaaactcagc gactacgaga ttcaattcca
    10201 aagaaccgcc tgggagagca tcttcccagg acttgattct ggtcactatc aggctgcggc
    10261 caataacttg agttacacaa aagagcgtgc tgaaaaatac ctttactcgc ttccaatttc
    10321 caacaatccc ctcgtccttg tcagcaacaa gaaaaatcct ttgacttctc ttgaccagat
    10381 cgctggtaaa acaacacaag aggataccgg aacttctaac gctcaattca tcaataactg
    10441 gaatcagaaa cacactgata atcccgctac aattaatttt tctggtgagg atattggtaa
    10501 acgaatccta gaccttgcta acggagagtt tgatttccta gtttttgaca aggtatccgt
    10561 tcaaaagatt atcaaggacc gtggtttaga cctctcagtc gttgatttac cttctgcaga
    10621 tagccccagc aattatatca ttttctcaag cgaccaaaaa gagtttaaag agcaatttga
    10681 taaagcgctc aaagaactct atcaagacgg aacccttgaa aaactcagca atacctatct
    10741 aggtggttct tacctcccag atcaatctca gttacaataa cactcttcga aaatctcttc
    10801 aaaccacgtc agctttatct gcaacctcaa agctgtgctt tgagcaacct acggctagct
    10861 tcctagtttg ctctttgatt ttcattgagt ataagatata ctaaaagcga ttggaccagc
    10921 caatcgcttt tttagtttgc attggctatt ttaggaaact cttacaaaaa atcaaaaaaa
    10981 ttcttcacat cctctacata cccatgcttt tctattaagc tggctaataa ttccagattg
    11041 tgcccctgat agttatcgtc acgacgcagt tcttcataca tttcgataaa gggaagcccc
    11101 ttggacttgg ccaattctaa ctcagcttcg taatcataag caactttacg aaattggata
    11161 ttgagtaatt ccccatcttc aacttctatc acggcatact gggcacggtg attttttaac
    11221 gcctcccaat taaaataggg catgccaatc gaccctggat tgatgatttg ttgcccttga
    11281 cttccataac gaagcaactg cttgtgaaca tgaccataaa ctgccacgtc cgtttccgca
    11341 tctagcaagt caccaccata gtttttgtca ggtaaattat gagagataga aaagcgcaat
    11401 ccgtcaattt ctttcttttc cagcaaaggc aagcttcgta gccagacaat cgttgcagga
    11461 tccattcgct ccatcaaata ctgtgtcata cgcaagagct gaacttcctg tgggtcttct
    11521 aagccatatt gcccatctaa agcctcaagg acacgatcat cccaattgcc tcgaacactt
    11581 gctgtgatag gaaggtcctt tagcagggcg actaagtcat ttgcgcctgg accaggaaga
    11641 aaaatatctc ccagaagcca atattcactg gccccttgat ttttagcatc tgcaatcact
    11701 gcttctagcg ccgtcgcatt gccatgaaca tctgataaaa ttgcgatttt atggttcatt
    11761 gtggtttcct tccgtttggt aatctactct ttattctgct acttgaggca aggcttctcc
    11821 ctgcgggttc aactttcttt gcacagcctc tgcaacgact ctaggtaccc caacttcgac
    11881 aatctcatcc acactggctt ccttgatttt ggtcaaagac ttgaaatgcc tcatgagatt
    11941 ttgcttgcgt ttaggtccca gaccatcaat cccatccaat tgagatgaga aagaattttt
    12001 ggagcgcagt tggcggtgga aagtgatagc aaagcggtgc acctcatctt ggatgcgttg
    12061 gaggaggaaa aattcctgag aattgcgaga caagtccacc acctcaagcg gatctccaaa
    12121 gagcaattca tgggtttggt gcttatcatt cttttgcagc ccagcaattg gaatatccaa
    12181 gcccagttcc tcttggataa cctgcttagc gatattgact tgaccttgcc ccccatcaat
    12241 cacaatcaaa tctggaggag tcaaagcctc acgctgtact cgaccatagc gtctgcgaat
    12301 gacctctctc atgctggcat agtcgtctgg tccaacaacc gtttttatct tgtacttacg
    12361 gtaatccttc ttactcggtt taccgttgac aaagaccacc atagccgaaa cagggctagt
    12421 tcccatgata ttagagttat cgaaggactc gatacgtact ggggtcggga tttggagcaa
    12481 acgccctaga ttttcaatag ctccttgagt cttttcgaca gatttttcta gcagattgaa
    12541 cttctgctct agactaacac gagcattttt tatggctaga ttgaccagtt gttttttctc
    12601 tccacgttga ggcttaagaa tcttggaatc caccaaggcc ttgacagcct cttcgtcaat
    12661 atcctgcgga atcagtacct cattgggaac tagatgagat ttttcttgat agaattgtcc
    12721 tacataggtc aaaaaatcct catctggatc attgaagtag gggaagagat tgacatcgcg
    12781 ctcgataagc ttaccctgac ggacaaagaa aacctgcaca cacatccagc ccttatccac
    12841 atagtagcca aagacatcgc gattttgcaa atctttcgcc atgacccgtt gcttggttcg
    12901 aagcgttcca atagcctgaa tcaggtcacg gtattccgcc gcacgttcaa actccatact
    12961 ttgtgctgct actgccattt tactcttgag atcatcgatg attttgtcat cctgaccttt
    13021 cagaaaatca gacacctcct gagccataga cttgaaataa gcctcatcct tcttacagat
    13081 ggtgtgggcc atacactggc cgatatggta ataaaaacag accttagagg gcgggttggt
    13141 acattttcga aaagggaaaa tcctatctag aagtcgcttg atttcattgg ctgcccccac
    13201 atctggataa gggccaaaat aaagaccacc gtcctttttg acctgacgag taatgataag
    13261 ccgtggatag cgctcattgg tgattttgat gaaaggatag gacttgtcat ccttgagcat
    13321 gatattgtac ttgggcttgt tttccttgat caggttgatt tctaggagaa gtgcctcaat
    13381 attagactcc gtaacaataa attcaaaatc cacaatttca gacaccagag cctctgtctt
    13441 ggtatcatga cttccacgaa aataggaccg tactcgatta cgcagatttt tagcctttcc
    13501 tacatagata atggtgccat ttttatcctt atgaatgtag caaccagggc tggtcggcaa
    13561 gagctctagt tttgatttaa tcaagttgtt catagttcca ttatagcaaa aaagtaggga
    13621 aagatagtac cctactcact agtctcatat atttttcgga ggtttgcaac atcctcttcc
    13681 tggataccat aaaaggaacc tgctggttgc atgacagact tctcatctgt atggtccaag
    13741 ccaatcgcat gacctaactc atgttctgcc gtatggacaa ggcgttcata ggagtagcca
    13801 tagtatggat tggacaaata ataatgattc aaccgcaccg ttacggacaa gaattgccct
    13861 gttaagagat tagtttgact ttccgcctct cctgccacag gagtgcctcc gtcgttcatc
    13921 tccgtagccg taatatccgc cttactagac tcagtcacga gttcaaagtt aaaagcacca
    13981 gtttgattcc agttctggat tgcttctaaa taagcctctt gaaagcgtga atccatctgc
    14041 ggatccaggt aaatacgagc agaggcctgt gcccaccttc cttcagaatg ctggtgacta
    14101 tctgtctggc ttaacttagg cagttgccct gttttctccc attggtcaat actttgttga
    14161 ccaattttta ctgaccgttc tgcttgcttt agcgctcctt gaaaatcccc gttcagatac
    14221 cagagaagtc cgaaagcaag cacacataag agcacaacta tccaaaccag acgccaaaac
    14281 aaacgccaca caaaagaaaa gaaagcccct atcaaacgaa aaagccagcg catgtctctc
    14341 cacctttcta gcaaataaga attattttac taaaagaagc taaaagaaat ctaaatactg
    14401 actttttcat cttaacgtcc tactattttt ttgagtaact ggatagcttt gtattttaaa
    14461 ggcgatggat ggtaacggaa agtacccgct ttgcgtacaa tatagccatt aaaattctgt
    14521 ttaaaacgca aaacaccatc acttccatca aaaatccctt gaatgcctag gaagttgtat
    14581 ttaggtattc cacgttttat gctttccaac ataacatatt tttgaagcag ggcaggggca
    14641 tagaacttat taaactcagt gtaggaacca ctaaagagat aagtcgtttc ctgaggcata
    14701 taaacaaata aactcccagc taaaacaata tcttcttctc catatttttc aatcaagtct
    14761 cgcgcttctg cttttcgaac ttcaaacgtt tcaaattgac tagaatattc tctcagttga
    14821 ttttgttttt tctcagaatg aggattttta ctcaaatcaa gtcgcaactt gtccaagttt
    14881 tcttctagtt tactttgttc accttgcaat ttgctcatat agtccgaaaa atttaagctt
    14941 gctatgagaa actccgcttg ttctccaaaa gtatcataaa aatgctcata atattctaaa
    15001 cttttatcac tatattctct acgttcagag gtttcttttg ttatattctt aaaaatcgat
    15061 agttcttcac gttttaactt tttcaaccga atgccaaagg tttcagcctt tttcaccaag
    15121 ggtttaccct ttttgctaaa acttttaagc aaactctttt cagttaattc agttaaatct
    15181 ttatagtata accaatctgg ttctccacct gggtaacctg ttgttaagcc atcaaattga
    15241 taacctaaat cagtcaaacc ttgaataata ctttttttct cagcatctat tggattacct
    15301 tggctatcaa aagtttgata agtttcataa ggttttacaa gcaactctaa tacaccattt
    15361 tgcttggcat attcttttaa ctctgcataa aaaactggaa gagcatcttg ttgggtataa
    15421 atcggccccg aattgagttc catatgcaga ccacccagca tgggcaagct ataaaccaga
    15481 gctgcaactt gaatttctcc ttcttgtttc aaagcaagat aaacaattcg agcccctctt
    15541 ttttctagca aatcccccat ctggacagat tgcataaagg aacgagaaga aacctgatca
    15601 gaataagtct gaaactcttc tttcgtgagt gttgttagtg ccatatactt actttctatg
    15661 tttttttctt aatgttttac ggaaatcaag agcaagtctt aacagaggat agagaggatg
    15721 agtgggcatt gtaaattcac ccaagtattc ttcaatcgtt ggattaaatt tttccttaaa
    15781 atgataaagt ccaccattga gagagttttc aacaccacct aaattttgcc aaaccatacc
    15841 tcgctcaaag gcatagcgag ccgtttcata ccatgttaaa attggtgcat tgtaacgttt
    15901 aaaatcatca tccataccag catatatatt gacagaggta gtaccaaatt ccaaactcaa
    15961 agtagccgct aaaggaactc tcgcttgacc tacatctata tattcctgca agaaggtcaa
    16021 ttcctctaac aaacgttctt tttccttctt ctgcgcttct acttttgaaa ttcgagtcga
    16081 ctcagtaaag gtctcttcca aggctctatt ttttgctaac tgttcttcta attcttgcga
    16141 acgtttagaa acatccaagg tggccaaggt gatataggcc ttgtccttaa aattatctaa
    16201 caatttttta taataggctt cattcctcaa atgaatctct tttcgcttct cagttttttt
    16261 catcaactcc gaaaatgaat ctaatagttc cagtccacca tattgaatct caagcccttt
    16321 gtttcgtgct gttcgaatag cctgttttgt tgacttggaa agtttatctt cttcaaaatt
    16381 ttccttgtat attttcgcct gaatacgagg ttgaatggtg tctcccattt cctccgtttt
    16441 tcctgaccac cttactccca tttgttgcaa actatcaata atagccagat tttcaggaaa
    16501 ttctgtcttt tcctgattga ttaaactttg agataggcaa atacttgggt caaaagtcac
    16561 aaaaaccgct ctcttactgc gagcatagga cttaatagac tgaatgacaa aattcaagag
    16621 ttctttatcc ccataatcca atataggtcc tcttgggatg taaaacattt tatagcctag
    16681 cggaagagtt ctaatcaaaa tactagctgt cgccagtaat ttttcttccc tgtaaacacc
    16741 aaacttctca tgttgccaat tagacttaac ttcctcccaa gcactacttt gtaatacatt
    16801 ggctaattca tgttctttga caaactgatc atattctaat gtgggaatgc caatttgata
    16861 acggtacatt tcctactctc tttcctccag tattttatta ctattctact actttcgttt
    16921 gaaaagtcta gtgaaaacat attttatttt agttctactc cccctatgct gaagttcaaa
    16981 ctaagtcagt ctctcttcta atttgaaatc aattggtagg gttgttaaaa aaacttccaa
    17041 ttgtttttcc cagtagtacc actcgtgagt tccagcgcta tggctatagg tcacatcaaa
    17101 acctagtttt ttgagatttt tcactgcgag attattggct tcgtacaaga aatcctgttc
    17161 gccacaccac gcccaaagtt tggtcttttt atccgatttt ttagccagac tttcaagaga
    17221 atagggacta gttgtccagt ctttaatctc tccaaaaaca cctctccagt aggctggact
    17281 tcccagattt tgactttcag gagaaaagtt ttgaaaactg agggcacctg aaaagctagc
    17341 tgcatgagaa aaacgatttg tcgcaagagc cagtttgaag cagccgtagc ctcccataga
    17401 aagaccagcg ataaaggtct tttcacgctt gctagtcata ttagggaaga agcgtttcag
    17461 aacctgtggc aattcctctg ctagagccgt gtagtagtca aaaccatact gggtatcggt
    17521 gtaccaacca ttgctggtat tgggcataac aacgatgaga ttagttcctc gaagcaagcg
    17581 ttctacattg gtccgcttaa gccaactatt atgatttcca gacatcccgt gcaaaaggta
    17641 caagacggga atatcttcac actctggttc ttccactcga ttggcatcag ggtagaggac
    17701 attcaccccc cactccatat ccaatacttg tgagtaatac tcgattttca ttactgccat
    17761 gattttctcc ttctattttt ctataagaaa aagccgaaac tcgactttct ctctgtttat
    17821 ttcaacgatt attttgcttc catgactact ggtaaaatag ctggacgacg cttggtttgg
    17881 tcaaagagat acttggtcaa attatctcga accttccctt taagatctgc ccagtcaaag
    17941 tcatctcctt gaagatactc ttctaccgtt tggttaatca attctgaact ttcatggaga
    18001 atatcgcgac tcttcttgag ataaacaaat ccgcgcgtat gaacacgagc cctagccaca
    18061 attttcttct cacgacggtt gactgtaata gccacgatga aaattccatc ctctgacaag
    18121 accttacggt cacgaagaac aacatttcca acatcaccaa tggcattccc atcaatcaag
    18181 atatctcctg ctgaaaccga tccagctgga acaaagtctc cattctcgta agccatggtc
    18241 gtcccctttt taggaatgaa gatgtgttct ggcaacatcc caactgccat ggcagcctta
    18301 gcgtgagcat ccaactcacg atactcccct tggacaggga agaggtactt aggttgcaaa
    18361 agattgatca tcagctgcaa atcacgcaca tttccgtgcc ctgatacatg taaactttgg
    18421 gtaatcaatt tgacaacccc acctgcctga taaatcatat tttccacacg cgcaacaaag
    18481 gcttctttag caatagacgg agccgtagca atatagacca ggtccccatc cttgatttct
    18541 acataacgat ggcgaccaat cgacatctta cgaagtccat tgataggttc acccatacga
    18601 cctgtctcaa gaataatcaa ctcatggtct tcaaagcgag acatatcttt aggcttaatc
    18661 aagagaattt cgttggctaa agacaacttc ttaagacgaa tcgctgtgcg gacgatattt
    18721 tcaatatcaa atcctgtcaa gacgatacgt cgacctgttt tatccgcagc gtcaaaaatc
    18781 tgctgaatac gagaaagatt actggaaaca gctgcaacga tgatacgacc ttcccagtca
    18841 gcaatagttt gggtaatttc atccctaact tcactttcac tagccacctg aatattgctg
    18901 tctgcattgg ccgaatcact gaggagagcc aggacgccgt cacgaccaat ctctgccaaa
    18961 cgagcaaaat cagttgcata agattcacta gccgtttggt caaatttgaa atcacctgta
    19021 taaacgatgc ttccttccga tgtcttcaag acaattccca gactctctgg aacggagtaa
    19081 gtcgtaggga agaaggaaac cactgtccca ccaaaatcaa tctccgtatt ctcatcaatg
    19141 acatggaaat cattaaattt cttaacggca tcatttcctt tgacaaagag ctttgccaac
    19201 tcaatggtca actcagaccc aaatacagga actttagcct ctgccaagag ataaggtaga
    19261 gcaccaatgg catccgcatg cccgtgggtc aagaaaaccc cagcaatacg gtcgctattt
    19321 tcaaaaaggt aatccatgtt tggaatcacc acatcgaccc ctaattgttc attttcagga
    19381 tattttaacc ctacattcaa aacaaaaatg gactctccaa tttcagcaat gtacatattt
    19441 tttccattct cacgcacacc accaagtgtt gttaaactga tattactcat ttttcctcca
    19501 aaatcttagt ttatcttgat tatagggcaa ctctaccctc ttattctaaa agttctaata
    19561 ctttcagccg aatcttttcc taccattata ccattttttt gatgattttc aaaatgaagg
    19621 tctgttttca aaaaagagtt gatttcccaa ctctttccta acttctactc tttttccatc
    19681 aaaaaatcat aaatttcttg caccgtaccc agcgccatca tttcttggtc tttaacggtt
    19741 tgtttgagat tttggtaaat ttgactttct cctatctccc gctttggcgc ctctttattg
    19801 actgtcatca caccatcttt tatcgtcaca aagcctagtt cttcaaatac ttgaatcatc
    19861 ttgaccagca agatttgttg aatattaaga tatgcagcca aatctttcag cttgtagcga
    19921 atatcaaact ctgggaactg gtaaatagtc ttgtacaatt tggcaaactg atctctagtc
    19981 ccataacctg tcagataata ggccttgtca atatcatttt tgaaatagac agcagagaaa
    20041 tgctgttcct gaaaaatggt cttcagctga gtaatatcct ctggaatgtt ttttacgaca
    20101 atagcttcac tagccgcaag atttggcagt tctccaggaa aatccaagac tggaacacct
    20161 tctggcaaga ctgcattttt tccacgaatg ttaaaaagtt gaacaccttc cactcgcgca
    20221 tccaccatca tcaactggag ggcagtttgg ccattccatt ggttgacaga caatttaacc
    20281 gctaactcta gattcttggt ttgagaaaac tctgtcgccc atctgccttg accaaaggct
    20341 accacttcaa aactcgcctc acccttggaa attttcagct ttagatgggc attacctgcc
    20401 cccatagtac gagcactttc gacctgaaaa ttcttgatat aaaaaatagg tttctgatta
    20461 tccattccaa aaggagctaa acgttcaaaa cttttgaccg tttccaagct aagtgcctcc
    20521 aaatccaact cttcatctag gtttaactta ttcttgccac cagcatctgc acctttttca
    20581 cgaacataat cttccaaaac ctgagataaa tctgagagtt gctcaacttc cagcgtcata
    20641 cccgctgcac ctgcatgacc tccaaaggcg atgaagaggt ctcgatgggg atccagagct
    20701 tcaaaaatat cgaccgcttc cacactacga gcactgccct tggcacgacc gtcttctata
    20761 ttaagaacaa tgactgtctg tcccaattct tccaataaac gaccagccac gattcctaga
    20821 accccaggat tccagccttc cttggccaag acctgaacct tcttctcagg atccaccatg
    20881 gtcttggctt cttcatagat agactgaacg atttccttgc gctcttcgtt tttctggtga
    20941 atcataaggg caatctcatg cgcttcctca tcatcaaatc cagtcaacaa atcaatggca
    21001 ggattgggat catccaagcg acccaaggca ttcaaacgag gagcaatctg gaaaccaacc
    21061 gtttcttctg ttacttcgtt ggcagcaatc ccagccatgt ccagcatttc ttgcagacca
    21121 atgcgctggg tatgacccaa catttccaga ccatattgaa ctaagatacg attttcatcc
    21181 gtcagactca ccatatctgc aatagttcca atagcgacca aatcaagcaa ttccacttgc
    21241 acttcttcta acagggcaca agccaacttg aaagcaactc cacaaccagc caaatattta
    21301 aaaggataat ccgcatctgg atgttcagga tggacaatag cataagcatc tggcagggtt
    21361 tcaggcatgg aatgatggtc tgtcacaatg acatctactc ccatagactg agccaatgca
    21421 atagcctcat gaccagcaac cccattgtcc accgtcacaa tcaaggaaat tccttcttgc
    21481 tcgataaagt atttataaac actagcatta gggccatagc catcggtaaa acgatttggc
    21541 aggtaaactc ggcactccgc accaagttgt tccaaacttt ccttcacaat agaagccgaa
    21601 gtcatgccat ccgcatcata gtctccataa acgagaatat tttccccttc ttcaatagcc
    21661 tgacgaatcc gctccactgc cttgtccata tcatggagca gataagcatc atgtaagtcc
    21721 tccaaggaag gttctaaaaa cttcttcaga ctttcttggt cctgaatccc tctctcaaac
    21781 aataaccgag ccacctcagg acccagtcca gccttcttgg ctatctttgt aaaatccgca
    21841 tcttctacct gcagggcaaa ctgccattca taagtaggtg ttatcaaaaa gacatccact
    21901 ctttctaaga attctattgc ttcattataa catgatttag acgttttctc tatccagatt
    21961 gcttttttat aacattttat agtatattga aactagaata gtacacctct acttataaaa
    22021 tattgttaga aatcgatttg actgtcccga tcgatttgtc cttttcttat ttcactatag
    22081 tgaatttttt cagatacggt ttgacaagaa cattctttta ttgtagaatt gtgttataaa
    22141 atctaacata aaggagatct ctcatggctt tagtagaatt taaaaacgtc gaaaaatatt
    22201 acggagacta ccacgcactc cgcaacatca atctccgttt tgaaaaagga caagttgttg
    22261 tcctgcttgg accttctggc tctgggaagt ccactcttat ccgtacgatc aatggtttag
    22321 aggctgttga caaaggaagt ctcctagtca atgggcacca agttgctggt gccagccaga
    22381 aagatttggt acctcttcgc aaggaagtcg gcatggtttt tcaacatttt aacctttatc
    22441 cacacaaaac ggtgttagaa aacgtgacac ttgcgcccat taaagttcta ggaattgata
    22501 aaaaagaagc tgaaaaaacc gcccaaaaat atctggaatt tgtaaatatg tgggacaaga
    22561 aagattccta tcccgccata ctatctggtg gacaaaaaca gcggatcgcc atcgctcgtg
    22621 gtcttgctat gcatccggaa ctcctcctct ttgatgaacc aacatctgct cttgatcctg
    22681 agactatcgg agatgttcta gcagttatgc agaaactggc gcatgatggg atgaacatga
    22741 tcatcgttac ccacgaaatg ggctttgctc gagaggttgc ggaccgcatt atctttatgg
    22801 ccgacggaga agttttatta gatacgacag atgtcgataa cttttttgac aatccaagca
    22861 aacctcgtgc ccaacaattc ctcagcaaaa ttatcaacca cgaaagtgac aaagtcaaat
    22921 aaggaggcgc ctatgaaaaa aaaattcttt ttatcagcat tattgattag ccttttcggc
    22981 cttgctgctg ccaaaccagt ccaggctgat actagtatcg cagacattca aaaaagaggc
    23041 gaactggttg tcggtgtcaa acaagacgtt cccaattttg gttacaaaga tcccaagacc
    23101 ggtacttatt ctggtatcga aaccgacttg gccaagatgg tagctgatga actcaaggtc
    23161 aagattcgct atgtgccggt tacagcacaa acccgcggcc cccttctaga caatgaacag
    23221 gtcgatatgg atatcgcgac ctttaccatc acggacgaac gcaaaaaact ctacaacttt
    23281 accagtccct actacacaga cgcttctgga tttttggtca ataaatctgc caaaatcaaa
    23341 aagattgagg acctaaacgg caaaaccatc ggagtcgccc aaggttctat cacccaacgc
    23401 ctgattactg aactgggtaa aaagaaaggt ctgaagttta aattcgtcga acttggttcc
    23461 tacccagaat tgattacttc cctgcacgct catcgtatcg atgccttttc cgttgaccac
    23521 tctattctat ctggctacac tagtaaacgg acagcactac tagatgatag tttcaagcca
    23581 tctgactaca gtattgttac caagaaatca aatacagagc tcaacgacta tcttgataac
    23641 ttggttacta aatggagcaa ggatggtagt ttgcagaaac tttatgaccg ttacaagctc
    23701 aaaccatcta gtcataccgc agattaagga ggatacccta tgacagattt atcatcttgg
    23761 acagcctatt ttcaggattt tggacaattt ttcaatggtt tcctctttac tcttgcccta
    23821 gcgattggat cctttatcct cgccatggtc ttaggaatct tctttggtgc catgtcaacc
    23881 agtaaacgtc caattttacg cattttagct cgcatcttcg tggaatttta ccaaaacact
    23941 cccctcttgg tgcagtttgt tattgttttt tatggcctac ctcttatcag tgaccacatc
    24001 atcatgattc caatttattg gacagccgtt ctctgcgtgg gactctatca cggcgcttat
    24061 atcgctgagg ttattcgttc agggattcag tctattccta gtggtcagat ggaggccgcc
    24121 ttgtcgcaag gttttaccta tatcagtgcc atgcgcttga ttatcttgcc tcaggccttc
    24181 cgcatcattc tccctccatt gaccaaccaa attgttaacc tcatcaagaa cacatctact
    24241 gtagctatca tctctggagt agacttgatg tttgtgacta agtcttggtc ggctctcaac
    24301 ggaaactata tcccagcctt tttaggtgct gctcttctct actttgccct atgcttccct
    24361 gttgcccagt ttggtcgcaa gatggagcaa gccaataaaa aagcctattc actttaggag
    24421 gttactatgg aatctatttt agaaatttta accccagata acctagtctt tatctttaaa
    24481 ggatttggct tgaccctcta tatttctctg attgccatca tcctctctac tatcatcggt
    24541 accgtgcttg ccgtcatgcg aaatggaaaa aatcctatct tacgcattat ttccagtatt
    24601 tatatcgagt ttgtgcgcaa cgttcccaac cttctctgga tttttactat ctttttggtg
    24661 ttcaaaatga aatccacacc agcaggtatt acagccttta ctctctttac atcagcagcc
    24721 ttggctgaga ttattcgagg cggtctcaat gccgtagaca agggacaata cgaagcagga
    24781 atgtcacaag gcttcacctc agcccaaatc ctctactaca tcattctccc acaagccatc
    24841 cgcaaaatgc taccagccat catttctcag tttgttaccg tgattaagga taccagtctc
    24901 ctctactctg ttatcgccct acaagaactc tttggagcca gccaaattct catgggccgt
    24961 tatttcgaac cagagcaggt cttcagtctt tacatcctga ttgccctcat ctacttcagc
    25021 tttaacctag cgatttctag cctgtctcat atgctagcca aacgttggca acaagctgca
    25081 gaataatact cttcgaaaat ctcttcaaac cacgtcagct tcaccttgcc gtactcaagt
    25141 acagcctgcg gctagcttcc tagtttgctc tttgattttc attgagtata aacagccact
    25201 ctccagttca attggagagt tttttgatga gagtagatat ttatagacct caatttgaca
    25261 ccatacattt tctatgataa aatgtaacaa attcatttac aacaaatcga aatctaaatg
    25321 aaatggaatt ttctatgaaa tcagtcaaag gactactctt tatcatagct agttttatct
    25381 tgactctttt gacttggatg aacacttctc cccaattcat gattccagga ctagctttaa
    25441 caagcctatc tctgactttt atcctagcca ctcgtctccc actactagaa agctggtttc
    25501 acggtttgga gaaggtctac accgtccaca aattcacagc ctttctctcc atcatcctac
    25561 taatctttca taactttagt atgggcggtt tgtggggctc tcgcttagct gctcagtttg
    25621 gcaatcttgc catctatatc tttgccagca tcatccttgt cgcctattta ggcaaataca
    25681 tccaatacga agcttggcga tggattcacc gcctggttta cctagcctat attttaggac
    25741 tctttcacat ctacatgata atgggcaatc gtctccttac atttaatctt ctaagttttc
    25801 ttgttggtag ctatgccctt ttaggcttac tagctggttt ttatatcatt tttctatatc
    25861 aaaagatttc cttcccctat ctaggaaaaa ttacccatct caaacgctta aatcacgata
    25921 ctagagaaat tcaaatccat cttagcagac ctttcaacta tcaatcagga caatttgcct
    25981 ttctaaagat tttccaagaa ggctttgaaa gtgctccgca tcccttttct atctcaggag
    26041 gtcatggtca aactctttac tttactgtta aaaattcagg cgaccatacc aataatatct
    26101 atgataatct tcaagccggc agcaaagtaa ccctagacag agcttacgga cacatgatca
    26161 tagaagaagg acgagaaaat caggtttgga ttgctggagg tattgggatc acccccttca
    26221 tctcttacat ccgtgaacat cctattttag ataaacaggt tcacttctac tataacttcc
    26281 gtggagatga aaatgcagtc tacctagatt tactccgtaa ctatgctcag aaaaatccta
    26341 attttgaact ccatctaatc gacagtacga aagacggcta tcttaatttt gaacaaaaaa
    26401 agtgcccgaa catgcaaccg tctatatgtg tggtcctatt tctatgatga aggcacttgc
    26461 caaacagatt aagaaacaaa atccaaaaac agagcttatt tacgaaggat tcaagttcaa
    26521 ataagtaatc atactctcct gggatttccc aggagagttt tttatagcca aatgaaataa
    26581 gacctgaacg atggaatttt ggcattcaaa tcaattgata agaatatttt atagtggagt
    26641 gaaataggat acgaacaaat tgattaggaa aatcaaatga atttatagaa atcttttagc
    26701 agttatgttg tcctattcta gtttcgaaac gctatagaag cagcattgtg ctagtctaga
    26761 ttcagtttac tatactaaaa cgagtagctt ggaatcaaaa aacccaccct cacaggcagg
    26821 ttttatctgt attattcagc tagattatgc tttaccttct gaaccgaata cgtcgatacg
    26881 ttcttcaacc gatgcttgga tagcttttac accgtcagcc aagaatttac gtgggtcgaa
    26941 gagttttttc ttgtcgtatt ctgcttcgtt tgcttcgtag tcacgagcaa atttacgagt
    27001 tgcgttagcg aatgcgattt ggcattctgt gttaacgtta actttggcaa caccaagttt
    27061 gatagctgct tggatttgct catcaggaat acctgatcca ccgtgcaata cgattgggaa
    27121 tcctggaaga gcttctgtca atttttgcaa gtggtcaagg tcaagacctt cccagtttac
    27181 tgggtaaggg ccgtggatgt taccgatacc agctgccaag aagtcgatac cagtttcaac
    27241 cattgcttta gcgtcttcga ttggagccaa ttcaccttta ccgatgattc cgtcttcttc
    27301 accaccgata gtaccaactt cagcttctac tgagatacct ttagcgtgtg ctttttcaac
    27361 aacttcttta gccaatttaa ggttttcttc aactggaagg tgtgaaccgt caaacatgat
    27421 tgaagtataa ccaacttcga tacactcaag tgcatcttcg tagtgaccgt ggtcaaggtg
    27481 gatagctact ggtacagtga tacccattga ttcaacaagg ttagcgatca agttgcgagc
    27541 aactttgtaa ccacccatgt atttagcagc acccattgaa gtttggatca aaactggagc
    27601 ttttttagct tctgctgcgc gcaagatagc ttgagtccac tcaaggttgt ttgtgttaaa
    27661 tccaccaact gcataaccgt tgtcacgggc tgcttggaca aatttttctg ctgaaacgat
    27721 tgccatttta tcaggcctcc tgtatatttt tatgggtcat cccatttaca ttgttcattt
    27781 tatcactttt tgccaaaaaa atctagtttt tcccgcagtt tcgattgatt ttcttctaac
    27841 tccatctatg taaacccttt ctctccctag tcttggacga cttttggaaa atctataaag
    27901 aaggttaaac gattctcctc catctcgaaa cgataagcta atttttcatg ttctaataga
    27961 ctcttaacca caaagagccc cataccagac cccttgacct tgcgactggc attgtcagaa
    28021 aaagactggg ctagtttttc ttgttcctct gagctacagc tattttcgat aaaaagttct
    28081 ccttctcttt ctccaattcg aactaagcca cctggaacag agtgcttaat ggcattgctg
    28141 atgagattag aaagaatcaa cttcataact gatgggttta gataagcctg ctgatgggtc
    28201 aaactattgt ctatctggag ctctctttcc ttggctagca aggcataatc tttgaccaga
    28261 ttttgcgtca tctggaggag gtcaattgtt tccctatcat ctcgcaattc ctgcacagaa
    28321 gagagggaaa gtatctgcag aacatggtga ttgagttcat ccacaatccc caaggcaact
    28381 cccagatact ggtctctatt cttataacga ccgatattct ctctcatatt ttcgattagg
    28441 attttcaaac tagccagcgg tgttttcaat tcatgagaag ctcctcgtag gaattcgacc
    28501 ttcatcttct ccagctggag aatggcttca ttcttttcat gcaagtccgc aataacagtc
    28561 aagagatgct ggtagaggct attgatttgt tccttgagat tgcctatctc atccttagaa
    28621 tccacgcgca atcgcacttg ggaatccagg tccatcatcc gacgggtcac ccgcttgatt
    28681 tccaaaatcg gtgcaacaat agtccgagcg tagatgtagg ccaccaagag ggaaatcaga
    28741 aaggaggcca gcaaggtata gggaagaaac tggagactga tttgctccgc ttccttttgt
    28801 aaatccatgg aagctagaaa ctggagaatc atagtaccac cgtcttgcgt tttcacctcg
    28861 cgctcctcaa taaagagaga ggttgtctgg cggtctgtgt ccagaggaag actgtccttg
    28921 acttctaact tgtcctcggt catctcacct ttgacggtcc ccttgatatc actagtctgg
    28981 gaatacaagt ctaacacttg ctcgatactc tgcctatctt tcccttctag ggactgggca
    29041 atggctgttg ccttttgacc aatggtttcc tgacgatgac tcagataagt cgaaggaaaa
    29101 agaaaataaa tagctaaatg aaggcagata accagaacac taaatatcga gaaggtatag
    29161 ataaatatct ttgtaaataa acctgttcgt ttcattttcg ctccaattta taaccaacat
    29221 tgcgcacagt gaggatacaa tccaagtcta gctttttccg caattccttg atataaacat
    29281 caataacacg gtcaaaggga acctcatctg tcgctttcca gacggcatcg ataatctgag
    29341 accgagtcaa ggcccggcct tcatttttca ctagatagtc cagaatttcc aactctttgg
    29401 cattgatagg cacttcttga cctgcgaggc ttgcactgta gctttcaaag tccaccttgg
    29461 tatccttgta agaaaagatt cgtcctgtat cgtagtagcg cttgaaaatc gcgtccaccc
    29521 tcacttttaa gagggagagg gagaaaggtt tttccagata gccatctgcc aaagaggcaa
    29581 aggcactcat cttgtattcc tcatcctgaa aagctgtcaa catcaagaca ggaacctgac
    29641 tggttttacg aatctcagct aggacttcta agccgttaag cttgggcatc tggatatcca
    29701 gtaaaaccag ggccacctca tagctagaaa attgctccag agcttcctga ccgtccgctg
    29761 cctcaatagt ttcatagcca caatccgtca aataatcact gaccccctca cggatcatct
    29821 cttcatcttc tacaattaaa attttcatac tttaactgct ctctattttt tatttttctt
    29881 agaataaata cctactctat tttctattat agtctcttgc tggccttttg tctgtaagca
    29941 actgaccact agataaaacg ttgtgaaatt cctttctcat aaattccata actttagtat
    30001 attatattta agcactaaag tacaaagaaa gcaactgaaa gcaatgattt tcaccactgc
    30061 tttcagattt attttgaatt gttaaatagc tattcctatc cactattctt gaatagaaac
    30121 acaagatgca atctttattc cagactcatt tttttcaaat ttattcacca tccagcaaga
    30181 gctcttttgg ttgttttcta aggagattgc ttgaagcaag cgccataacg agaaccacta
    30241 gaaccaaggc aaggacaaaa atgatgataa agtctgatgt ctgaatggaa atgtctaggc
    30301 tcgacaaggt cttgctaaag ccatctactt ctgcaccgcc accaaggtta gaggcttgag
    30361 ccgccttact agcctgtttg gcaacacctg aagtcacatt ggcaaggaca gtgtttccaa
    30421 ttgcacgggc agtgtaatta gctaggaagt aagcagaaac tagagcaggg atagcaatca
    30481 agatagattc ggtgatgaat tgacccaaga tacttgcctg cttgagacca atagagagga
    30541 ggattcccac ttccttgcga cgggcattga tccaaagact gagcaagagg gcaaggagaa
    30601 ggactgagaa gctcaagcta ccccagaaga ggaggttggc catcttgtac ataccagaga
    30661 tagattgctc aagagctggg tagttagagg agctcttgac gagtgtgtag ctcttccagt
    30721 tgataccact gatgccattc aactctttca taacatcatc caagttcttg tctgctgtta
    30781 caaagaaggt tgcgtcccca taaatggctg tgtcttctgt gtatccataa agttttgcag
    30841 cagtgtgaat gtctgtaata gctgtgtttt cgtaaagttc ttgtgagtag gttactgctg
    30901 acttattatg accatcaaag agtcccttga ttgtcacttc aactgtttcc ttggctcctt
    30961 tttcattatc tgcatcgtag atattagagt ccagtttaac cttgtcccct actttccagc
    31021 cgtgtttggc tgccaagtcc ttgtgcaaga ggattttatc cttgtcgtcg ttggttaagt
    31081 gctctccttc gactagttta taagaaccag agacaaactt atcttcttta gaggagtcat
    31141 tgacacctgt aatcatcaag ctacttccaa aacgtttggc acgatcagca gtgagattct
    31201 tcttggtttc tggcgtttca atcaggtcat atccagtcaa atctccgata gcgttgatac
    31261 gtttgacata agactcaatg gccttgtttt cggtgatttt tttgatgtct tcacccttga
    31321 tattcccagc accacgaggc gttccttggt tgacgcgacg attgatttgc atggagaagc
    31381 tattggtgat atttttaaag gtctcctgag aagccttggc agtagctccc ttgattgaca
    31441 agccgaccaa actcaagctc gccataagga gaataatcag gaagatgaca atcgatttga
    31501 aaaacttcct tgtaacatag gcaaatgcgt tgtgtaacat agattccctt tctagatttt
    31561 gttttaatca ttctatcaaa ataagctcaa attatttact agtattgcgc gtttcagtca
    31621 gtttcttatc ctttaattca agtgtaatat ctgacgcttg tgccacttct ttactgtgag
    31681 ttacgacaat cacacattta cctgttttct gggcaagtga tttgagtagt tcgacaatat
    31741 ctccagcagt tttaggatcc agatttcctg ttggctcatc agctagaata actggagctt
    31801 ctgagaccaa actgcgagca atggcaacac gttgctgttg accacctgat aactggagaa
    31861 cattccgctt aatctggctt tcatccaaac caagctcaag aagtgtattc ttgcttgcct
    31921 ttttgttgac caattggata ttttccagcg gagaaagata atctatcaag ttataatttt
    31981 gaaagaccag ggaaatatgg tgcatgcgat ggtaagaata gcccttctta cgaatatcct
    32041 ctccttgaaa aaggatagaa ccttcaacag gactatctag accagcaagt agggacaaga
    32101 gtgtggattt tcctgctcct gactccccaa taatactgta aaattttccg ggttcaaaat
    32161 tataattgat ctgatatagg actgcttcag cagtattctt ataacggtag gtaacatctt
    32221 gtaattgtaa taaagtcatg atttctcctt cttaactaat agatgataaa atttctttcg
    32281 gtgattttct aaataagaat aggaaacaaa gggctacaga taagcaacta agcagaacta
    32341 gaaaaacata ggattctgca aaagataaga tgctagttga taaactgctt gctttggcta
    32401 gtgtatcttg taagcttacc tgatctccac ttgctagtag agtttggagt aggtaagttg
    32461 tgattccgtt tcctgcaaca aatgctggaa gcaaagctcc aagagatacc aaaactacct
    32521 ctaaacagaa ttgtaggaag atcgagctct tgccttttcc aagtgcaagt aaaatcccca
    32581 cttcatagac ccgttctctc aaccagagag acaaaaccag aattaaggct ccagctcctg
    32641 ctatcaacat cccataaagg aagatggtca ggaaggtttg gaaagttgca actgagtctt
    32701 tgatttgttc aaaagccttg ttttcctttt cgacttggta gccttgattt tccaaggcca
    32761 agttttctac ctgcttcatg agtccgtcca tttccttagg attttctaca tagaagcgtg
    32821 ctgcactgac ttgagcttca ctattgccca aaagggtttg gctactttca taatctgtaa
    32881 agacttgatt ttcactgaag tcagaagaca agcctgtgaa tttctcttgt tttttaccag
    32941 aaaagatgcc gataatctca aactctactg tttgtccttt tccagattca gactgaccag
    33001 catccaagcc aatcttgtca tgaagtgaaa gaccgttctt cttagccaat tcttcgtgga
    33061 taaggatttt cttggaatcc cctttttgaa ggtgtcgccc ttcttttaga ttgaaagccg
    33121 aactggtaaa ggttacatcc ttggatgaat cctcaagagc cgttaagcta accaagttat
    33181 tgtctgcagc tgataaatca tcacgctcca cgctctgctc gccagtcact gcttccttgt
    33241 cttttagttt tgcgaccgtc tcaagttcag gagagacatt ttccagcccc ttaatcttgc
    33301 ttacagatgc taggtctgac aacttgaatg tctgaccatt ctctatcttc ttaatagaaa
    33361 aagatgtatt gagtgattta taaagattgc tttctactgt tttgttggac ttcatcagag
    33421 tcaaacaggc tgaaattccg gccaataaga ccaataaaat cagaaataaa ataaaacttc
    33481 tcagtcgctt tctgctgaca taagcccaag atctttggat tggattcatt tgtcacctcc
    33541 atatttgtaa gactattata aaacccaaat atgaaatgtt tatgaaatac gaaaaaaaat
    33601 atcgagtagg ggataatctc tagcccctct cacaccaccg tacgtg
//
LOCUS       DAVBOD010000019        30962 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 640-05
            SAMEA1012484-rid20186543.denovo.019, whole genome shotgun sequence.
ACCESSION   DAVBOD010000019 DAVBOD010000000
VERSION     DAVBOD010000019.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012484
            Sequence Read Archive: ERR059358
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 30962)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 30962)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979948.1
            Genome Coverage       :: 595x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:03:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,266
            CDSs (total)                      :: 2,219
            Genes (coding)                    :: 2,091
            CDSs (with protein)               :: 2,091
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 71 of 128
            Pseudo Genes (incomplete)         :: 50 of 128
            Pseudo Genes (internal stop)      :: 33 of 128
            Pseudo Genes (multiple problems)  :: 22 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..30962
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012484-rid20186543.denovo.019"
                     /strain="NIG 640-05"
                     /db_xref="taxon:1313"
     gene            289..2790
                     /locus_tag="VQ862_000976"
     CDS             289..2790
                     /locus_tag="VQ862_000976"
                     /EC_number="6.1.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014639013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucine--tRNA ligase"
                     /protein_id="HET3115342.1"
                     /translation="MSFYNHKEIEPKWQGYWAEHHTFKTGTDASKPKFYALDMFPYPS
                     GAGLHVGHPEGYTATDILSRYKRAQGYNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTA
                     ENIANFKRQINALGFSYDWDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVE
                     ELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLNDLDELDWSESIKD
                     MQRNWIGKSTGANVTFKVKGTDKEFTVFTTRPDTLFGATFTVLAPEHELVDAITSTEQ
                     AEAVADYKHQASLKSDLARTDLAKEKTGVWTGAYAINPVNGKEIPIWIADYVLASYGT
                     GAVMAVPAHDQRDWEFAKQFDLPIVEVLEGGNVEEAAYTEDGLHVNSDFLDGLNKEDA
                     IAKIVACLEEKGCGQEKVTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLV
                     LPVTKDIRPSGTGESPLANLTDWLEVTREDGVKGRRETNTMPQWAGSSWYYLRYIDPH
                     NTEKLADEDLLKQWLPVDIYVGGAEHAVLHLLYARFWHKFLYDLGVVPTKEPFQKLFN
                     QGMILGTSYRDHRGALVATDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDV
                     VEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLITSKEIIAENNGALD
                     KVYNETVKAVTEQIESLKFNTAIAQLMVFVNAANKEDKLYVDYAKGFIQLIAPFAPHL
                     AEELWQTVAATGESISYVAWPTWDESKLVEDEIEIVVQIKGKVRAKLMVAKDLSREEL
                     QEIALADEKVKVEIDGKEIVKVISVPNKLVNIVVK"
     gene            2984..3679
                     /locus_tag="VQ862_000977"
     CDS             2984..3679
                     /locus_tag="VQ862_000977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001144916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET3115343.1"
                     /translation="MPVNEYGQMIGESMEGYTPGELPSIDFLEGRYARIEALSVEKHA
                     EDLLAVYGPDTPQEMWTYLFQEPVADMGELVSLLHQMLARKDRFYYAIIDKATGKALG
                     SFSLMRIDQNNRVIEVGAVTFSPELRGTRIGTEAQYLLARYVFEELNYRRYEWKCDAL
                     NLPSRRAAERLSFIYEGTFRQAVVYKGRTRDTDWLSMIDKDWPQVKDRLETWLRPENF
                     DKNGQQYKSLREL"
     gene            3691..4107
                     /locus_tag="VQ862_000978"
     CDS             3691..4107
                     /locus_tag="VQ862_000978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET3115344.1"
                     /translation="MITIKKQEIVKLEDVLHLYQAVGWTNYTHQPEMLEQALSHSLVI
                     YLALDGDAVVGLIRLVGDGFSSVLVQDLIVLPIYQRQGIGSALMKEALEDYKDAYQVQ
                     LVTEETERTLGFYRSMGFEILSTYNCIGMTWMNRKK"
     gene            complement(4922..5014)
                     /locus_tag="VQ862_000979"
     CDS             complement(4922..5014)
                     /locus_tag="VQ862_000979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="HET3115345.1"
                     /translation="MMELVLKTIIGPIVVGVVLRIVDKWLNKDK"
     gene            5175..6146
                     /gene="ruvB"
                     /locus_tag="VQ862_000980"
     CDS             5175..6146
                     /gene="ruvB"
                     /locus_tag="VQ862_000980"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000502070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration DNA helicase
                     RuvB"
                     /protein_id="HET3115346.1"
                     /translation="MGDEELVERTLRPQYLREYIGQDKVKDQLQIFIEAAKMRDEALD
                     HVLLFGPPGLGKTTMAFVIANELGVNLKQTSGPVIEKAGDLVAILNELEPGDVLFIDE
                     IHRLPMSVEEVLYSAMEDFYIDIMIGAGEGSRSVHLELPPFTLIGATTRAGMLSNPLR
                     ARFGITGHMEYYAHADLTEIVERTADIFEMEITHEAASELALRSRGTPRIANRLLKRV
                     RDFAQIMGNGVIDDIITDKALTMLDVDHEGLDYVDQKILRTMIEMYSGGPVGLGTLSV
                     NIAEERETVEDMYEPYLIQKGFIMRTRSGRVATAKAYEHLGYEYSEK"
     gene            6127..6699
                     /locus_tag="VQ862_000981"
     CDS             6127..6699
                     /locus_tag="VQ862_000981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001098890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase family protein"
                     /protein_id="HET3115347.1"
                     /translation="MNTVKNKQEILEAFRENPDMMAILTIIRDLGLKDSWLAAGSVRN
                     FIWNLLSDKSPFDHETDIDVIFFDPDFSYEETLLLEKKLREDFPQYQWELKNQVYMHQ
                     HSPHTASYTSSRDAMSKYPERCTTVGLRLNEESDFELYAPYGLEDILNFQVRPTPHFL
                     ENEDRMELYQTRLSKKNWQEKWKNLIFKNT"
     gene            6930..7688
                     /locus_tag="VQ862_000982"
     CDS             6930..7688
                     /locus_tag="VQ862_000982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000466694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenyl transferase"
                     /protein_id="HET3115348.1"
                     /translation="MFGFFKKDKAVEVEVPTQVPAHIGIIMDGNGRWAKKRMQPRVFG
                     HKAGMEALQTVTKAANKLGVKVITVYAFSTENWTRPDQEVKFIMNLPVEFYDNYVPEL
                     HANNVKIQMIGETDRLPKQTFEALTKAEELTKNNTGLILNFALNYGGRAEITQALKLI
                     SQDVLDAKINPGDITEELIGNYLFTQHLPKDLRDPDLIIRTSGELRLSNFLPWQGAYS
                     ELYFTDTLWPDFDEAALQEAILAYNRRHRRFGGV"
     gene            7697..8500
                     /locus_tag="VQ862_000983"
     CDS             7697..8500
                     /locus_tag="VQ862_000983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000189872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidate cytidylyltransferase"
                     /protein_id="HET3115349.1"
                     /translation="MTQDLQKRTLFAGIALAIFLPILMIGGLLLQIAIGIIAMLAMHE
                     LLKMRGLETMTMEGLLTLFATFALTIPLENYLTFLPVDGNVVAYSVLISIMLGTTVFS
                     KSYTIEDAVFPLAMSFYVGFGFNALLDARVAGLDKALLALCIVWATDSGAYLVGMNYG
                     KRKLAPRVSPNKTLEGALGGILGAILVTIIFMIVDSTVALPYGIYKMSVFAIFFSIAG
                     QFGDLLESSIKRHFGVKDSGKFIPGHGGVLDRFDSMLLVFPIMHLFGLF"
     gene            8522..9781
                     /gene="rseP"
                     /locus_tag="VQ862_000984"
     CDS             8522..9781
                     /gene="rseP"
                     /locus_tag="VQ862_000984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000900658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RIP metalloprotease RseP"
                     /protein_id="HET3115350.1"
                     /translation="MLGILTFILVFGIIVVVHEFGHFYFAKKSGILVREFAIGMGPKI
                     FAHIGKDGTAYTIRILPLGGYVRMAGWGDDTTEIKTGTPVSLTLADDGKVKRINLSGK
                     KLDQTALPMQVTQFDFEDKLFIKGLVLEEEKTFAVDHDATVVEADGTEVRIAPLDVQY
                     QNATIWGKLITNFAGPMNNFILGVVVFWVLIFMQGGVRDVDTNQFHIMPQGALAKVGV
                     PETAQITKIGSHEVSNWESLIQAVETETKDKTAPTLDVTISEKGSDKQVTVTPEDSQG
                     RYLLGVQPGVKSDFLSMFVGGFTTAADSALRILSALKNLIFQPDLNKLGGPVAIFKAS
                     SDAAKNGIENILYFLAMISINIGIFNLIPIPALDGGKIVLNILEAIRRKPLKQEIETY
                     VTLAGVVIMVVLMIAVTWNDIMRLFFR"
     gene            9794..11647
                     /locus_tag="VQ862_000985"
     CDS             9794..11647
                     /locus_tag="VQ862_000985"
                     /EC_number="6.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HET3115351.1"
                     /translation="MKQSKIPIPTLREMPSDAQVISHALMLRAGYVRQVSAGVYSYLP
                     LANRVIEKAKNIMRQEFEKIGAVEMLAPALLSAELWRESGRYETYGEDLYKLKNREKS
                     DFILGPTHEETFTAIVRDSVKSYKQLPLNLYQIQPKYRDEKRPRNGLLRTREFIMKDA
                     YSFHANYDSLDSVYDEYKAAYERIFTRSGLDFKAIIGDGGAMGGKDSQEFMAITSART
                     DLDRWVVLDKSVASFDEIPAEVQEEIKAELLKWIVSGEDTIAYSSESSYAANLEMATN
                     EYKPSNRVVAEEEVTRVATPDVKSIDEVAAFLNVPEEQTIKTLFYIADGELVAALLVG
                     NDQLNEVKLKNHLGADFFDVASEEEVANVVQAGFGSLGPVGLPENIKIIADRKVQDVR
                     NAVVGANEDGYHLTGVNPGRDFTSEYVDIREVREGEISPDGQGVLNFARGIEIGHIFK
                     LGTRYSASMGADVLDENGRAVPIIMGCYGIGVSRLLSAVMEQHARLFVNKTPKGEYRY
                     AWGINFPKELAPFDVHLITVNVKDEEAQALTEKLEASLMGAGYEVLTDDRNERVGVKF
                     SDSDLIGLPIRITVGKKAADGIVEVKIKATGDTIEVHADNVLETLEILSKK"
     gene            11746..13125
                     /gene="bglA"
                     /locus_tag="VQ862_000986"
     CDS             11746..13125
                     /gene="bglA"
                     /locus_tag="VQ862_000986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000943526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HET3115352.1"
                     /translation="MLRFPKDFVWGSSTSGPQTEGRVAGDGKGDNLWDYWFQVEPNRY
                     YNGIGSDKTSTFYENWERDIELLLETGHTAFRTSIQWSRIFPQGCGKVNPQGVDFYRK
                     VFEAIKAKGIRLLVNLYHFDLPFALQEDGDGWENKATVSAYEDYARFCFETYGDLVDQ
                     WITFNEPIVPVEFGYFYDAHYPHKVDAEAAVKVAYHTQLASSRAVKACHELLPDSKIG
                     IVLNLTPAYPRSQHPADVKAARIAALFQAQSFLDPSVLGTYPQELVEILHEHGLLPDA
                     TEEELELIRDNTVDFLGVNYYQPLRVMAPRFAKHPESPLLPEHFYEPYVMPGRKINSH
                     RGWEIYEQGIYDIAQNIKENYGNIEWMLTENGMGVEGEEKFRQDGMIQDDYRIDFVKG
                     HLRELHRAIEDGANCKGYLIWTFIDCWSWLNSYKNRYGLVELDLETQERRLKKSGHWF
                     KELSDNNGF"
     gene            13318..15126
                     /gene="glmS"
                     /locus_tag="VQ862_000987"
     CDS             13318..15126
                     /gene="glmS"
                     /locus_tag="VQ862_000987"
                     /EC_number="2.6.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014621492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--fructose-6-phosphate transaminase
                     (isomerizing)"
                     /protein_id="HET3115353.1"
                     /translation="MCGIVGVVGNTNATDILIQGLEKLEYRGYDSAGIFVLDGADNHL
                     VKAVGRIAELSAKTAGVEGTTGIGHTRWATHGKPTEDNAHPHRSETERFVLVHNGVIE
                     NYLEIKEEYLAGHHFKGQTDTEIAVHLIGKFAEEEGLSVLEAFKKALHIIRGSYAFAL
                     VDSQDPEVIYVAKNKSPLLIGLGEGYNMVCSDAMAMIRETNQYMEIHDQELVIVKADS
                     VEVQDYDGNRRERASYTAELDLSDIGKGTYPYYMLKEIDEQPTVMRKLIQAYTDEAGQ
                     VVVDPDIIKAVQDADRIYILAAGTSYHAGFASKKMLEELTDTPVELGISSEWGYGMPL
                     LSKKPLFIFISQSGETADSRQVLVKANEMGIPSLTVTNVPGSTLSREANYTMLLHAGP
                     EIAVASTKAYTAQIAALAFLAKAVGEANGNAKAQAFDLVHELSIVAQSIESTLSEKET
                     IEAKVRELLETTRNAFYIGRGQDYYVAMEASLKLKEISYIQCEGFAAGELKHGTIALI
                     EEGTPVLALLSDPVLANHTRGNIQEVAARGAKVLTIAEENVAKDTDDIVLTTVHPYLS
                     PISMVVPTQLVAYFATLHRGLDVDKPRNLAKSVTVE"
     gene            complement(15264..15341)
                     /locus_tag="VQ862_000988"
                     /pseudo
     CDS             complement(15264..15341)
                     /locus_tag="VQ862_000988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            15398..16447
                     /locus_tag="VQ862_000989"
     CDS             15398..16447
                     /locus_tag="VQ862_000989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LLM class flavin-dependent oxidoreductase"
                     /protein_id="HET3115354.1"
                     /translation="MVELGISTFGEITELEGTGQTYSHAERIRQLVAEIELADKVGLD
                     VYGIGEHHRADFAVSAPEIVLAAGAVNTKKIRLTSAVSILSSMDPIRLFQQYATIDAL
                     SNGRAEIMAGRGSFTESFPLFGYDLKDYDSLFDEKLDLLQLVNEKTKLDWQGRLTQTI
                     AGKEVYPRPVQDKLPLWIATGGHVESTVKIAQAGLPIVYAIIGGNPRYFKKLIQAYRE
                     IGSEAGHADKDLKVGAHSWGWIAEDGEQAVKDYFHPTKQVVDAISKDRPHWQELRYEQ
                     YLEQVGPNGAMFVGNPDQVAEKLIRMIEDLGLDRFMLHLPLGSMPHDQVLRAIELFGT
                     QVAPKVRAYFAMKEA"
     gene            complement(16547..20317)
                     /gene="spuA"
                     /locus_tag="VQ862_000990"
     CDS             complement(16547..20317)
                     /gene="spuA"
                     /locus_tag="VQ862_000990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored pullulanase SpuA"
                     /protein_id="HET3115355.1"
                     /translation="MRKTPSHTEKKMVYSIRSLKNGTGSVLIGASLVLLAMATPTISS
                     DESTPTTNEPNNRNTTTLAQPLTDTAAGSGKNESDISSPRNANASLEKTEEKPATEPT
                     TSTSPVTTETKAEEPIEDNYFRIHVKKLPEENKDAQGLWTWDDVEKPSENWPNGALSF
                     KDAKKDDYGYYLDVKLKGEQAKKISFLINNTAGKNLTGDKSVEKLVPKMNEAWLDQDY
                     KVFSYEPQPAGTVRVNYYRTDGNYDKKSLWYWGDVKNPSSAQWPDGTDFTATGKYGRY
                     IDIPLNEAAREFGFLLLDESKQGDDVKIRKENYKFTDLKNHSQIFLKDDDESIYTNPY
                     YVHDIRMTGAQHVGTSSIESSFSTLVGAKKEDILKHSNITNHLGNKVTITDVAIDEAG
                     KKVTYSGDFSDTKHPYTVSYNSDQFTTKTSWRLKDETYSYDGKLGADLKEEGKQVDLT
                     LWSPSADKVSVVVYDKNDPDKVVGTVALEKGERGTWKQTLDSTNKLGITDFTGYYYQY
                     QIERQGKTVLALDPYAKSLAAWNSDDAKIDDAHKVAKAAFVDPAKLGPQDLTYGKIHN
                     FKTREDAVIYEAHVRDFTSDPAIAKDLTKPFGTFEAFIEKLDYLKDLGVTHIQLLPVL
                     SYYFVNELKNHERLSDYASSNSNYNWGYDPQNYFSLTGMYSSDPKNPEKRIAEFKNLI
                     NEIHKRGMGAILDVVYNHTAKVDIFEDLEPNYYHFMDADGTPRTSFGGGRLGTTHHMT
                     KRLLVDSIKYLVDTYKVDGFRFDMMGDHDAASIEEAYKAARALNPNLIMLGEGWRTYA
                     GDENMPTKAADQDWMKHTDTVAVFSDDIRNNLKSGYPNEGQPAFITGGKRDVNTIFKN
                     LIAQPTNFEADSPGDVIQYIAAHDNLTLFDIIAQSIKKDPSKAENYAEIHRRLRLGNL
                     MVLTAQGTPFIHSGQEYGRTKQFRDPAYKTPVAEDKVPNKSHLLRDKDGNPFDYPYFI
                     HDSYDSSDAVNKFDWTKATDGKAYPENVKSRDYMKGLIALRQSTDAFRLKSLQDIKDR
                     VHLITVPGQNGVEKEDVVIGYQITAPNGDIYAVFVNADEKAREFNLGTAFAHLRNAEV
                     LADENQAGSVGIANPKGLEWTEKGLKLNALTATVLRVSQNGTSHESTAEEKPDSTPSK
                     PEHQDPAPEARPDSTKPDAKVADAENKPSQATADSQAEQPAQEAQASSVKEAVQNESV
                     ENSSKKNIPVTPDKQAELPNTGIKNENKLLFAGISLLALLGLGFLLKNKKEN"
     gene            20734..21147
                     /gene="rpsL"
                     /locus_tag="VQ862_000991"
     CDS             20734..21147
                     /gene="rpsL"
                     /locus_tag="VQ862_000991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12"
                     /protein_id="HET3115356.1"
                     /translation="MPTINQLVRKPRKSKVEKSKSPALNVGYNSHKKVQTNVSSPQKR
                     GVATRVGTMTPKKPNSALRKFARVRLSNLIEVTAYIPGIGHNLQEHSVVLLRGGRVKD
                     LPGVRYHIVRGALDTAGVNDRKQGRSKYGTKRPKA"
     gene            21167..21637
                     /gene="rpsG"
                     /locus_tag="VQ862_000992"
     CDS             21167..21637
                     /gene="rpsG"
                     /locus_tag="VQ862_000992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S7"
                     /protein_id="HET3115357.1"
                     /translation="MSRKNRAPKRDVLPDPLYNSQLVTRLINRVMLDGKRGTAASIVY
                     GAFEQIKEATGNDALEVFETAMENIMPVLEVRARRVGGSNYQVPVEVRPERRTTLGLR
                     WLVTIARLRGEHTMQDRLAKEILDAANNTGAAVKKREDTHRMAEANRAFAHFRW"
     gene            22062..24143
                     /gene="fusA"
                     /locus_tag="VQ862_000993"
     CDS             22062..24143
                     /gene="fusA"
                     /locus_tag="VQ862_000993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HET3115358.1"
                     /translation="MAREFSLEKTRNIGIMAHVDAGKTTTTERILYYTGKIHKIGETH
                     EGASQMDWMEQEQERGITITSAATTAQWNNHRVNIIDTPGHVDFTIEVQRSLRVLDGA
                     VTVLDSQSGVEPQTETVWRQATEYGVPRIVFANKMDKIGADFLYSVSTLHDRLQANAH
                     PIQLPIGSEDDFRGIIDLIKMKAEIYTNDLGTDILEEDIPAEYLDQAQEYREKLVEAV
                     AETDEELMMKYLEGEEITNEELKAGIRKATINVEFFPVLCGSAFKNKGVQLMLDAVID
                     YLPSPLDIPAIKGINPDTDAEETRPASDEEPFAALAFKIMTDPFVGRLTFFRVYSGVL
                     QSGSYVLNTSKGKRERIGRILQMHANSRQEIETVYSGDIAAAVGLKDTTTGDSLTDEK
                     AKIILESINVPEPVIQLMVEPKSKADQDKMGIALQKLAEEDPTFRVETNVETGETVIS
                     GMGELHLDVLVDRMRREFKVEANVGAPQVSYRETFRASTQARGFFKRQSGGKGQFGDV
                     WIEFTPNEEGKGFEFENAIVGGVVPREFIPAVEKGLVESMANGVLAGYPMVDVKAKLY
                     DGSYHDVDSSETAFKIAASLALKEAAKSAQPAILEPMMLVTITVPEENLGDVMGHVTA
                     RRGRVDGMEAHGNSQIVRAYVPLAEMFGYATVLRSASQGRGTFMMVFDHYEDVPKSVQ
                     EEIIKKNKGED"
     gene            24247..28638
                     /locus_tag="VQ862_000994"
     CDS             24247..28638
                     /locus_tag="VQ862_000994"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000071418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PolC-type DNA polymerase III"
                     /protein_id="HET3115359.1"
                     /translation="MSNSFEILMNQLGIPVEMRQHPALTQADIERVVVHKISKVWEFH
                     FVFSNILPIEIFLELKKGLSEEFSKTGNKAVFEIKVLSQDFSNQLLQAYYREAFSEGP
                     CASQSFKSLYQNLQVRAEGNQLFIEGSEAIDKEHFKKNHLPNLAKQLEKFGFPTFNCQ
                     VEKNDVLTQEQEDAFHAENEQIVQAANEEALRAMEQLEQMAPPPAEEKPAFDFQTKKA
                     AAKPKLDKAEITPMIEVTTEENRLVFEGVVFDVEQKVTRTGRVLINFKMTDYTSSFSM
                     QKWVKNEEEAQKFDLIKKNSWLRVRGNVEMNNFTRDLTMNVQDVQEVVHYERKDLMPE
                     GERRVEFHAHTNMSTMDALPEVEEIVATAAKWGHKAVAITDHGNVQSFPHGYKAAKKA
                     GIQLIYGMEANIVEDRVPIVYNEVERDLSEATYVVFDVETTGLSAIYNDLIQVAASKM
                     YKGNVIAEFDEFINPGYPLSAFTTELTGITDDHVKNAKPLEQVLQEFQEFCKDTVLVA
                     HNATFDVGFMNANYERHGLPKISQPVIDTLEFARNLYPEYKRHGLGPLTKRFGVALEH
                     HHMANYDAEATGRLLFIFIKEVAEKHGVTDLARLNIDLISPDSYKKARIKHATIYVKN
                     QVGLKNIFKLVSLSNTKYFEGVPRIPRTVLDAHREGLILGSACSEGEVFDAVVSQGVD
                     AAVEVAKYYDFIEVMPPAIYAPLIAKEQVKDMEELQTIIKNLIEIGDRLGKPVLATGN
                     VHYIEPEEEIYREIIVRSLGQGAMINRTIGHGEHAQPAPLPKAHFRTTNEMLDEFAFL
                     GEELARKLVIENTNALAEIFEPVEVVKGDLYTPFIDKAEETVAELTYKKAFEIYGNPL
                     PDIVDLRIEKELTSILGNGFAVIYLASQMLVQRSNERGYLVGSRGSVGSSFVATMIGI
                     TEVNPLSPHYVCGQCQYSEFITDGSYGSGFDMPNKDCPNCGHKLSKNGQDIPFETFLG
                     FDGDKVPDIDLNFSGEDQPSAHLDVRDIFGEEYAFRAGTVGTVAAKTAYGFVKGYERD
                     YGKFYRDAEVERLAQGAAGVKRTTGQHPGGIVVIPNYMDVYDFTPVQYPADDVTAEWQ
                     TTHFNFHDIDENVLKLDVLGHDDPTMIRKLQDLSGIDPNEIPMDDEGVMALFSGTDVL
                     GVTPEQIGTPTGMLGIPEFGTNFVRGMVDETHPTTFAELLQLSGLSHGTDVWLGNAQD
                     LIKQGIADLSTVIGCRDDIMVYLMHAGLEPKMAFTIMERVRKGLWLKISEEERNDYIE
                     AMKANKVPEWYIESCGKIKYMFPKAHAAAYVMMALRVAYFKVHHPIYYYCAYFSIRAK
                     AFDIKTMGAGLEVIKRRMEEISEKRKNNEASNVEIDLYTTLEIVNEMWERGFKFGKLD
                     LYRSQATEFLIDGDTLIPPFVAMDGLGENVAKQLVRAREEGEFLSKTELRKRGGLSST
                     LVEKMDEMGILGNMPEDNQLSLFDELF"
     gene            28740..29003
                     /locus_tag="VQ862_000995"
     CDS             28740..29003
                     /locus_tag="VQ862_000995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelB/DinJ family
                     antitoxin"
                     /protein_id="HET3115360.1"
                     /translation="MSKMSISIRLDSEVKEQAQQVFSNLGMDMTTAINIFLRQAIQYQ
                     GLPFDVRLDENRKLLQALTDLDQNRNMSQSFESVSDLMEDLRA"
     gene            28996..29274
                     /locus_tag="VQ862_000996"
     CDS             28996..29274
                     /locus_tag="VQ862_000996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013904578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system YafQ family
                     toxin"
                     /protein_id="HET3115361.1"
                     /translation="MLKIRYHKQFKKDFKLAMKRGLKAELLEEVLNFLVQEKEHPARY
                     RDHSLTASKHFQGVRECHTQPDWLLVYKVDKSELILNLLRTGSHSDLF"
     gene            29295..29447
                     /locus_tag="VQ862_000997"
     CDS             29295..29447
                     /locus_tag="VQ862_000997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000776615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3115362.1"
                     /translation="MKLRIFAEDKPAKKVFEYQLELADRTILLSTALLSGAIALAGIF
                     SALREK"
     gene            29469..30710
                     /locus_tag="VQ862_000998"
     CDS             29469..30710
                     /locus_tag="VQ862_000998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000243957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HET3115363.1"
                     /translation="MVLPNFKENLEKYAKLLVANGINVQPGHTLALSIDVEQRELAHL
                     IVKEAYALGAHEVIVQWTDDVINREKFLHAPMERLDNVPEYKIAEMNYLLENKASRLG
                     VRSSDPGALNGVDADKLSASAKAMGLAMKPMRIATQSNKVSWTVAAAAGLEWAKKVFP
                     NAASDEEAVDFLWDQIFKTCRVYEADPVKAWEEHAAILKSKADMLNKEQFSALHYTAP
                     GTDLTLGLPKNHVWESAGAVNAQGEEFLPNMPTEEVFTAPDFRRADGYVTSTKPLSYN
                     GNIIEGIKVTFKDGQIVDITAEKGDQVMKDLVFENAGARALGECALVPDPSPISQSGI
                     TFFNTLFDENASNHLAIGAAYATSVVDGAEMSEEELEAAGLNRSDVHVDFMIGSNQMD
                     IDGIREDGTRVPLFRNGNWAN"
     gene            30720..30950
                     /locus_tag="VQ862_000999"
     CDS             30720..30950
                     /locus_tag="VQ862_000999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000901571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HET3115364.1"
                     /translation="MLGSMFVGLLVGFLAGAMTNRGERMGCFGKMFLGWIGAFLGHLL
                     FGTWGPVLSGTAIIPAILGAMIVLAIFWRRGS"
BASE COUNT         8793 a         5924 c         7247 g         8998 t
ORIGIN      
        1 gttcttcata aatcaaaaag cgacataggt agtcggctat ttattgtgaa tacattaatt
       61 agcattccag ttttatcttc ggtctaaaat aagtattttg tgctatacga gataagcttc
      121 ttgacttact ccttgattta ctgcataaca atgggataaa aagtgggaga tagagcaatt
      181 catagtcatc aaaattaatg agatacagta tacagttttt cctttaaaca catttcaaat
      241 tccctcaaaa atggtataat agtaacatca caaaattgga gagagaccat gagtttttac
      301 aatcataaag aaattgagcc taagtggcag ggctactggg cagaacatca tacatttaag
      361 acaggaacag atgcatcaaa acctaagttt tatgcgcttg atatgttccc ttatccgtct
      421 ggagctggtc tgcacgtagg acacccagaa ggttatactg caaccgatat cctcagtcgt
      481 tacaaacgtg cgcaaggcta caatgtcctt cacccaatgg gttgggatgc ttttggtttg
      541 cctgcagagc aatacgctat ggatactggt aatgacccag cagaatttac agcggaaaac
      601 attgccaact tcaaacgtca aatcaatgcg cttggatttt cttatgactg ggatcgtgaa
      661 gtcaacacaa cagatccaaa ctactacaag tggactcaat ggattttcac caagctttac
      721 gaaaaaggct tggcctatga agctgaagtg ccagtaaact gggttgagga attgggaact
      781 gccattgcca atgaagaagt gcttcctgac ggaacttctg aacgtggagg ctatccagtt
      841 gtccgcaaac caatgcgcca atggatgctc aaaatcacgg cttacgcaga gcgcttgctc
      901 aatgacttag atgaactaga ttggtcagag tctatcaagg atatgcaacg caactggatt
      961 ggtaaatcaa ctggtgccaa tgtaactttc aaagtaaaag gaacagacaa ggaatttaca
     1021 gtctttacta ctcgtccgga cacacttttc ggtgcgactt tcactgtttt ggctcctgaa
     1081 catgaattag tagatgccat cacaagcaca gagcaagcag aagcagtagc agactacaaa
     1141 caccaagcca gccttaagtc agacttggct cgtaccgacc ttgccaaaga aaaaactggt
     1201 gtatggactg gtgcttatgc catcaatcct gtcaatggta aggaaattcc aatctggatt
     1261 gcggattacg ttcttgctag ctatggtaca ggtgcggtaa tggctgtgcc tgcccacgat
     1321 caacgtgact gggaatttgc caaacaattt gaccttccaa tcgtcgaagt acttgaaggt
     1381 ggaaatgttg aagaagctgc ctacacagaa gatggccttc acgttaattc agacttccta
     1441 gatggactca acaaagaaga cgctattgcc aagattgtgg cttgcttgga agaaaaaggc
     1501 tgtggacaag agaaggtaac ctaccgtctc cgcgactggc tctttagccg tcaacgttac
     1561 tggggtgagc caatcccaat cattcattgg gaagatggaa cttcaacagc tgtccctgaa
     1621 agtgaattgc cacttgtctt gcctgtaacc aaggatatcc gtccctcagg tactggtgaa
     1681 agtccactag ctaacttgac agactggctt gaagtgactc gtgaagatgg tgtcaaaggt
     1741 cgtcgtgaaa caaatactat gccacaatgg gcaggttcaa gctggtacta cctccgctat
     1801 attgacccac acaatactga gaaattggct gacgaggatc tgctcaaaca atggttgcca
     1861 gtagatatct acgtgggtgg tgcggaacat gctgtacttc acttgcttta cgctcgtttc
     1921 tggcataaat tcctctatga cctcggtgtt gttccaacta aggaaccatt ccaaaaactc
     1981 tttaaccaag ggatgatttt gggaacaagc tatcgtgacc accgtggggc tcttgtggcg
     2041 actgacaagg ttgaaaaacg tgatggttct ttcttccatg tggaaacagg ggaagagttg
     2101 gagcaagcgc cagccaagat gtctaaatcg ctcaagaacg ttgtcaaccc agacgatgtg
     2161 gtggaacaat acggtgccga tacccttcgt gtttatgaaa tgttcatggg cccacttgat
     2221 gcttcaatcg cttggtcaga agaaggtctg gaaggaagtc gtaaattcct tgaccgtgtt
     2281 tatcgtttga ttacaagtaa ggaaattatt gcggaaaaca atggtgctct tgacaaggtt
     2341 tataacgaaa ccgttaaagc tgtcacagag caaatcgaat cattgaaatt caacacagct
     2401 attgcccaac ttatggtctt tgtcaacgcc gctaacaagg aagacaagct ctatgtggac
     2461 tatgccaaag gatttatcca attgattgcg ccatttgcac ctcacttggc agaagaactt
     2521 tggcaaactg ttgcagcaac aggtgaatca atctcttacg tagcttggcc aacatgggat
     2581 gaaagtaaat tggttgaaga cgaaatcgaa atcgtcgtcc aaatcaaagg taaagtccgt
     2641 gccaaactca tggttgctaa agacctgtca cgtgaagaat tgcaagaaat tgctcttgct
     2701 gatgaaaaag tcaaggtaga aattgacggt aaggaaatcg tgaaagtgat tagtgtacca
     2761 aataaattgg ttaatattgt tgtaaaataa ccaatttatt tgctgatttc caacctcaaa
     2821 cagtttccca aactgtttga gccaactaaa ctcgttaata tcgttgtgaa ataaggtagg
     2881 aatccttcag agtagaatct ggaggatttt ttgaatcttc ttatgaaagt atggtatact
     2941 atgggcaact ataaagtttg aaaagtgaaa aaaggagaaa gctatgccag taaatgaata
     3001 tggtcaaatg attggggagt caatggaagg ttatacacca ggtgaactgc cttctattga
     3061 tttcttagaa gggcgttatg ctaggataga ggctctttca gtggaaaagc atgcggagga
     3121 tttgctagct gtttatgggc ctgatacgcc tcaggagatg tggacctacc tttttcagga
     3181 gccagtagca gatatggggg agctggttag ccttttacat cagatgttgg ctcgtaagga
     3241 ccgtttttac tatgcaatca tagacaaggc gactggtaag gctttgggat ctttttctct
     3301 catgcgcatt gaccagaata accgagtaat agaagtcgga gcagtcactt tttctccaga
     3361 gctaaggggt acacggatag gaactgaagc tcagtatctc ctagctcgct atgtttttga
     3421 ggagctaaac tatcgtcgct acgagtggaa atgcgatgcc ttaaatctgc catccagacg
     3481 agctgcggag cgtttgagct ttatttatga aggaaccttc cgtcaggcag tggtttataa
     3541 gggacgtacg agagatacgg attggttgtc tatgattgat aaggactggc ctcaagtcaa
     3601 agatcgtttg gaaacatggt tgcgtcctga aaattttgat aaaaatggac agcagtacaa
     3661 gagcttgaga gaactttaag aggtgttgag atgattacta ttaaaaagca agaaattgtc
     3721 aagctagagg atgttttaca tctctatcag gctgtcggtt ggacaaatta tacccatcaa
     3781 ccagagatgc tggagcaggc cttatctcat tcattagtaa tttatctggc acttgatggt
     3841 gatgctgtgg tgggcttgat tcgtttggtt ggagatggat tctcatcagt attggttcag
     3901 gatttaatcg ttttaccaat ctatcagcgt caaggaattg gtagtgcctt gatgaaagag
     3961 gctttagagg attacaaaga tgcctatcaa gtccagctgg tgacagaaga gacagaaaga
     4021 accttgggct tctatcgttc tatgggcttt gaaatcttat ccacctataa ttgtataggg
     4081 atgacttgga tgaatcgtaa aaaataacaa aacttgtttt ttcttaagca aaatttaagg
     4141 atggtctagt attatatagt cattaaataa agacctccta actttattta ataaaatcct
     4201 aaactttttt catcacaatc tcctaatgaa gccacccaat caggtggctt ttttgcgtgg
     4261 tgaggtgctg gtgatagaaa ttttttgcaa aatagtaaaa ttttagaaaa gttaagctag
     4321 ttttaagttt cgtcttgtat catgtagtta ttaaataaag acctcctaac tttatttaat
     4381 aaaatcctaa acttttcttt ttcataataa tctcccttaa ctccacccaa tcaggtggag
     4441 ttttttagct ctatttcagg cttttgggga ctattctaaa aataattttt cgatattttt
     4501 cggtattttt cggattttgg tcggggaatt ggcggggact tttttagcga atataactaa
     4561 gaaataggtc tgtggtcgct tcagctagtt caaactcaat ttgattgtaa gtgactgtta
     4621 attgaagaac tggaactact gtaataatga ttttgcttgt ctagtagtgg cgtattaaat
     4681 gaaaagtgac atgtaagatt gtctcttcgt ttacgaaatc aaaatttcta tgaaattgat
     4741 agaatcccta acgttctctt aatcttaacc gtcttgtcgt acagcggttg aagaaaatgt
     4801 aaacctttga caaaattcgt gaactatggg ataataaaaa ggaattgagt actagttcta
     4861 tatcataggc tagaaaagac cccaagctca cgaccaaata agcttgaggt cttttttgac
     4921 actatttgtc cttgtttagc catttatcga ctatacgaag aacgacaccg accacaattg
     4981 gtccgatgat agttttgagt actaattcca tcatgggcta tctcacctcc tttcgtaggc
     5041 ggtgtagaag tgtcgtagaa tattatacca cataagtgct aaacttagga gtcacccaat
     5101 caggtggctt ttttgtttgt ggcttggttt tttgatataa tagagccatg agtagaattt
     5161 tagataatga gataatgggg gatgaggagt tagtagaacg cacgctccgt cctcagtatt
     5221 tacgtgaata tatcggacag gataaggtca aggaccagct acaaatcttt attgaagctg
     5281 ccaaaatgcg ggatgaagcg ctggatcatg tgctcttatt tgggcctcca ggtctcggga
     5341 aaacgaccat ggcctttgtt attgccaacg aactgggagt caatcttaag cagacgtcgg
     5401 gtccagtcat tgaaaaagcc ggagatctgg tagctatttt gaatgagtta gagcctgggg
     5461 atgtactttt tattgatgag atccatcgtt tgccaatgtc agtggaagag gtgctttata
     5521 gtgctatgga ggacttctac atagatatta tgattggggc tggtgagggt agtcgtagtg
     5581 ttcatttgga gttaccacct tttaccttga ttggtgcgac gactcgggct ggtatgctct
     5641 ccaatccgct acgggcacgt tttgggatta caggccatat ggagtattat gcccatgctg
     5701 acttgacaga aattgtcgag cggacggcag atatttttga gatggaaatc actcatgagg
     5761 cagcatctga gttggcccta cgtagtcgtg ggacccctcg tattgccaat cgtctcctca
     5821 agcgcgtgcg cgattttgcc cagataatgg ggaatggggt aattgatgat attattaccg
     5881 ataaggcttt gactatgctg gatgttgacc atgaaggttt ggactatgtg gatcaaaaaa
     5941 tccttcgtac catgattgag atgtacagtg gaggacctgt tggtctagga actctttctg
     6001 tgaatatcgc cgaagagcgt gagacagttg aagatatgta tgagccttac ttgattcaaa
     6061 aaggttttat catgcggaca cggtctggac gggtggcgac tgctaaggca tatgagcact
     6121 taggttatga atacagtgaa aaataagcaa gaaatcttag aggcttttag agaaaatcca
     6181 gatatgatgg ccattctgac gatcatccga gaccttggtc tgaaagactc gtggttggca
     6241 gcaggttctg tcagaaattt catttggaat cttttgtcag acaaatcccc ttttgatcat
     6301 gaaacagata tagatgtgat tttctttgat ccagattttt cttatgagga aaccttatta
     6361 ctggagaaaa agctgcgaga ggattttcct cagtaccagt gggaattgaa aaatcaggtc
     6421 tatatgcatc agcacagtcc tcacactgct tcctatacca gttctcgtga tgctatgagt
     6481 aagtatccag aacggtgtac gacagttgga ctgcgcttga atgaagaatc agattttgaa
     6541 ctctatgcac cttatggttt ggaggatatt ttgaattttc aagttcgtcc aactcctcat
     6601 ttcttagaaa atgaagaccg aatggaactc tatcaaacac gtttatccaa gaaaaattgg
     6661 caggagaaat ggaaaaattt gatttttaaa aatacttaag gaaactttaa gctagggagt
     6721 gtacactaag ttcataagtt aagaagacct taacttaaac tcctaaaact ttttcataat
     6781 aatctcccta taaaaataaa gtcgcccaat caggcggctt atttttttga aaaatgggct
     6841 tggtgcctga gaataaatag cttagtgata gaagaaaatg gggaaatatg gtataataaa
     6901 acgatagatt tttgaatagg aataagatca tgtttggatt ttttaagaaa gataaggctg
     6961 tggaagtaga ggttccgaca caggttcctg ctcatatcgg catcatcatg gatggcaatg
     7021 gccgttgggc taaaaaacgt atgcaaccgc gagtttttgg acataaggcg ggcatggaag
     7081 cattgcaaac cgtgaccaag gcagccaaca aactgggcgt caaggttatt acggtctatg
     7141 ctttttctac ggaaaactgg acccgtccag atcaggaagt caagtttatc atgaacttgc
     7201 cagtagagtt ttatgataat tatgtcccgg aactacatgc gaataatgtt aagattcaaa
     7261 tgattgggga gacagaccgc ctgcctaagc aaacctttga agctttaacc aaggctgagg
     7321 aattgactaa gaacaacaca ggattgattc ttaattttgc tcttaactat ggtggacgtg
     7381 ctgagattac acaggcgctt aagttgattt cccaggatgt tttagatgcc aaaatcaacc
     7441 caggtgacat cacagaggaa ttgattggta actatctctt tactcagcat ttgcctaagg
     7501 acttacgaga cccagacttg attatccgta ctagtggaga attacgtttg agcaatttcc
     7561 ttccatggca gggagcctat agtgagcttt attttacgga caccttatgg cctgattttg
     7621 acgaagcggc cttgcaggaa gctattcttg cctataatcg tcgtcatcgc cgatttggag
     7681 gagtttagga ggaaatatga cccaggattt acagaaaaga accttgtttg cagggattgc
     7741 cctggctatt ttcctaccaa ttttaatgat tgggggcctc ttgcttcaga tagcaatcgg
     7801 aatcatagcc atgctagcca tgcatgaact tttgaagatg agaggtctag agaccatgac
     7861 gatggagggc ctcttgaccc tctttgcaac ctttgcattg accattccct tggagaatta
     7921 cctgactttt ttgccagttg atgggaatgt ggttgcctat agtgttttga tttcaatcat
     7981 gttaggaacg accgttttta gcaagtctta tacgattgag gatgcggttt tccctcttgc
     8041 tatgagcttc tacgtgggct ttggatttaa tgctttacta gatgctcgtg ttgcaggttt
     8101 ggacaaggct ctcttagcct tgtgtatcgt ctgggcgaca gacagtggtg cctatcttgt
     8161 tgggatgaac tatgggaaac gaaagttagc accaagggta tcgcctaata aaacccttga
     8221 gggtgccttg ggtggtattt taggagcaat tttagtaacc attatcttta tgatagttga
     8281 cagtacagtt gctcttccat atggaattta caagatgtca gtctttgcta ttttctttag
     8341 cattgctgga caatttggtg atttactaga aagttcgatc aaacgtcatt ttggtgttaa
     8401 ggattctggg aaatttatcc ctggacatgg tggtgttttg gatcgtttcg atagtatgtt
     8461 gcttgtattt ccaatcatgc acttatttgg actcttttaa tcaaaagacg gaggaaacgc
     8521 tatgctcgga attttaacct ttattctggt tttcgggatt attgtagtgg tgcacgagtt
     8581 cgggcacttc tactttgcca agaaatcagg gattttagta cgtgaatttg ccatcggtat
     8641 gggacctaaa atttttgctc acattggtaa ggatggaacg gcctatacca ttcgaatctt
     8701 gcctctgggt ggctatgtcc gcatggccgg ttggggtgat gatacaactg aaatcaagac
     8761 aggaacgcct gttagtttga cacttgctga tgatggtaag gttaaacgca tcaatctctc
     8821 aggtaaaaaa ttggatcaaa cagccctccc tatgcaggtg acccagtttg attttgaaga
     8881 caagctcttt atcaaaggat tggttctgga agaagaaaaa acatttgcag tggatcacga
     8941 tgcaacggtt gtggaagcag atggtactga ggttcggatt gcacctttag atgttcaata
     9001 tcaaaatgcg actatctggg gcaaactgat taccaatttt gcaggtccta tgaacaattt
     9061 tatcttaggt gtcgttgttt tttgggtttt aatctttatg cagggtggtg tcagagatgt
     9121 tgataccaat cagttccata tcatgcccca aggtgccttg gccaaggtag gagtaccaga
     9181 aacggcacaa attaccaaga ttggctcaca tgaggttagc aactgggaaa gcttgatcca
     9241 agctgtggaa acagaaacca aagataagac ggcaccgact ttggatgtga ctatttctga
     9301 aaaggggagt gacaaacaag tcactgttac acccgaagat agtcaaggtc gttaccttct
     9361 aggtgttcaa ccgggggtta agtcagattt tctatccatg tttgtaggtg gttttacaac
     9421 tgctgctgac tcagctctcc gaattctctc agctctgaaa aatctgattt tccaaccgga
     9481 tttgaacaag ttgggtggac ctgttgctat ctttaaggca agtagtgatg ctgctaaaaa
     9541 tggaattgaa aatatcttgt acttcttggc aatgatttcc atcaatattg ggatttttaa
     9601 tcttattccg attccagcct tggatggtgg taagattgtg ctcaatatcc tagaagccat
     9661 ccgccgcaaa ccattgaaac aagaaattga aacctatgtc accttggccg gagtggtcat
     9721 catggttgtc ttgatgattg ctgtgacttg gaatgacatt atgcgactct tttttagata
     9781 atcgaggaat attatgaaac aaagtaaaat acctatccca acgcttcgcg aaatgccaag
     9841 cgatgctcaa gttatcagcc atgctcttat gttgcgtgct ggttatgttc gccaagtttc
     9901 agcaggtgtt tattcttatc taccacttgc caaccgtgtg attgaaaaag ctaaaaacat
     9961 catgcgccaa gaattcgaaa agattggtgc tgttgagatg ttggctcctg cccttcttag
    10021 tgcagaattg tggcgtgaat caggtcgtta cgaaacctat ggtgaagacc tttacaaact
    10081 aaaaaaccgt gaaaaatcag actttatctt aggtccaact cacgaagaaa cctttacagc
    10141 tattgtccgt gattctgtta aatcttacaa gcaattgcca ctcaaccttt atcaaattca
    10201 gcccaagtat cgtgatgaaa aacgcccacg taatggactt cttcgtacac gtgagtttat
    10261 catgaaggat gcttatagtt tccacgctaa ctatgatagt ttggatagtg tttatgatga
    10321 gtacaaagca gcctatgagc gtattttcac tcgtagtggt ttagacttca aggctattat
    10381 tggtgacggt ggagccatgg gtggtaagga tagccaagaa tttatggcca ttacatctgc
    10441 tcgtacagac cttgaccgct gggttgtctt ggacaagtca gttgcctcat ttgacgaaat
    10501 tcctgcagaa gtgcaagaag aaatcaaggc agaattgctc aaatggatag tctctggtga
    10561 agataccatt gcttactcaa gtgagtctag ctatgcagct aacttagaaa tggcaacaaa
    10621 cgagtacaaa ccaagcaacc gtgttgtcgc tgaagaagaa gttactcgtg ttgcaacgcc
    10681 agatgttaaa tcaattgatg aagttgcagc tttcctcaat gttccagaag aacaaacgat
    10741 taaaaccctc ttctacattg cagatggtga gcttgttgca gcccttctag ttggaaatga
    10801 ccaactcaac gaagtcaagt tgaaaaacca cttaggagca gatttctttg acgttgctag
    10861 cgaagaagaa gtggcgaatg ttgttcaagc aggatttggt tcacttggac cagttggttt
    10921 gccagagaat attaaaatta ttgcagatcg taaggtgcaa gatgttcgca atgcagttgt
    10981 cggtgctaac gaagatggct accacttgac tggtgtgaac ccaggccgtg attttacttc
    11041 agaatatgtg gatatccgtg aagttcgtga gggtgaaatt tccccagatg gacaaggtgt
    11101 ccttaatttt gcgcgtggta ttgagatcgg tcatattttc aaactcggaa ctcgctattc
    11161 agcaagcatg ggagcagatg tcttggatga aaatggtcgt gctgtgccaa tcatcatggg
    11221 atgttacggt atcggtgtca gccgtcttct ttcagcagtg atggagcaac acgctcgcct
    11281 ctttgttaac aaaacgccaa aaggtgaata ccgttacgct tggggaatca atttccctaa
    11341 agaattggca ccatttgatg tgcatttgat tactgtcaat gtcaaggatg aagaagcgca
    11401 agccttgaca gaaaaacttg aagcaagctt gatgggagct ggttatgaag tcttgacaga
    11461 tgaccgtaac gaacgtgtcg gtgttaaatt tagcgatagt gacttgattg gtcttccaat
    11521 ccgtatcact gttggtaaaa aagcggccga tggcattgta gaagttaaga tcaaggcaac
    11581 tggtgacacc attgaggttc atgcagataa cgtgcttgaa acgcttgaaa tcctaagcaa
    11641 gaaataaaaa ctataatcag aagaaaaaca aggaaaaaat gtaactagtt tttaccttgt
    11701 tttttctgta taatgggaga aatgagtaga taaagaggta aatgtatgct aagatttcca
    11761 aaggattttg tctggggatc ctctacttct ggaccgcaga cagaaggacg tgtagctggt
    11821 gacggtaagg gagacaatct ctgggattac tggttccaag tggagccaaa tcgttactat
    11881 aatgggattg gttcagataa gacatcgact ttttatgaaa attgggagcg ggatattgag
    11941 cttttgttag agactggtca cacagccttt cggacttcta ttcagtggtc acggattttt
    12001 ccacaaggct gtggaaaagt caaccctcaa ggtgtggatt tttatcgtaa ggtctttgag
    12061 gctattaagg ctaaaggaat tcgtctgtta gtcaatctct atcattttga tttacctttt
    12121 gcccttcaag aggatggtga tggttgggaa aataaggcga cagtctcagc ctatgaagac
    12181 tatgctcgtt tttgttttga gacttatgga gatttagtgg atcaatggat tacctttaac
    12241 gagcccatcg ttcctgtaga atttggttat ttttatgatg cccattatcc acataaggtg
    12301 gatgcagagg cagctgttaa ggtagcctat catacacaat tggccagcag ccgggctgtt
    12361 aaggcttgcc atgaactttt gcctgattcc aagattggga ttgtcctcaa cttgacaccg
    12421 gcttatccac gtagccagca tcctgctgat gtcaaggcag ctcgtattgc ggcccttttt
    12481 caggcccaat ctttcttaga tccatctgtc ttggggactt atccacagga gttggtagaa
    12541 atcttgcatg aacacggtct tttacctgat gctacagagg aagagttgga actcattcgt
    12601 gataatacgg tggacttcct tggtgtgaac tactatcaac ctttgcgtgt tatggctcct
    12661 cgatttgcta agcatccaga gagtccactc ttaccagaac atttttacga gccttatgtg
    12721 atgcctggac gtaaaatcaa ttctcaccgt ggttgggaga tttatgagca agggatttat
    12781 gacatcgccc aaaatatcaa ggaaaattat ggcaatattg agtggatgtt gactgagaat
    12841 ggtatgggtg ttgaagggga agaaaaattc cgtcaagatg gaatgattca agatgattac
    12901 cgtattgact ttgtaaaagg tcatcttcgt gaacttcacc gtgccattga agatggtgcc
    12961 aactgtaagg gctacttgat ttggaccttt attgactgct ggtcatggct caacagctat
    13021 aaaaatcgct atggtttggt cgaattagac ttggaaacgc aagaacgtcg tctgaagaaa
    13081 tcaggccact ggttcaaaga attaagcgat aataatggat tttaaaaagg actctgactg
    13141 attatcccaa tcggtcagag tttttatgct tacaggagct taatttgaac tataccaatt
    13201 tttactcttg acaagtgaaa gaaacaagta tatactgttt ttgctgattc tataaaagat
    13261 gaattagact ataccaattt taaggagaaa gcacagcttg cctgtgtcgt atatactatg
    13321 tgtggaattg ttggtgttgt tggaaacaca aatgcaactg atattttgat tcaagggctt
    13381 gaaaagcttg aataccgtgg ctatgattct gcgggaattt ttgtcctaga tggtgctgat
    13441 aaccatttag tgaaggcggt tggtcgtatt gcagaattgt ctgccaagac agctggtgtt
    13501 gagggaacaa ctggtatcgg acatactcgt tgggctactc acggaaaacc aactgaggac
    13561 aatgctcacc cacaccgctc tgagacagaa cgctttgtct tggtgcataa tggggtgatt
    13621 gagaactatc ttgaaatcaa ggaagaatac cttgcaggtc accacttcaa ggggcagaca
    13681 gatactgaaa tagccgttca tttgattgga aaatttgcgg aagaagaagg gctctcagtt
    13741 cttgaagcct tcaaaaaagc ccttcacatc atccgtggtt cttatgcctt tgccttggtt
    13801 gactcacaag atcctgaagt catctacgta gctaaaaata aatcaccact tttgattggt
    13861 cttggagaag gctataacat ggtctgctca gacgccatgg ctatgattcg tgaaactaac
    13921 caatacatgg aaatccatga ccaagagttg gtaatcgtca aggctgatag tgtggaagtt
    13981 caagactatg atggaaatcg tcgtgagcgt gctagctaca ctgctgaact tgacttgtca
    14041 gatatcggta agggaactta cccttactac atgctcaagg aaattgacga gcaaccaact
    14101 gttatgcgga aactcatcca agcctacaca gatgaggctg gtcaagttgt cgtagaccca
    14161 gatatcatta aggctgttca agacgcagac cgcatctaca tccttgcagc tggaacatct
    14221 taccatgcag gatttgcttc taagaaaatg ttggaagaat tgacagatac accagttgaa
    14281 cttggaatct catctgagtg gggctacggt atgccacttc tcagcaagaa accactcttc
    14341 atctttatca gccaatctgg tgaaacagcg gatagtcgtc aagttttggt caaggctaat
    14401 gaaatgggaa ttccaagctt aacagtgaca aacgttccag gttcaaccct ctcacgtgaa
    14461 gccaactata ccatgctcct tcacgcaggt cctgaaattg ccgtggcatc aactaaagcc
    14521 tatacagcgc aaatcgcagc ccttgccttc cttgcaaaag cagtcggaga agcaaatggt
    14581 aatgctaaag cgcaagcctt tgacctggtt catgaattgt caatcgtagc tcagtctatc
    14641 gaatcaactc tttcagagaa agaaaccatt gaagccaagg ttcgtgaact tcttgaaaca
    14701 actcgtaacg ccttttacat cggacgtggt caagattact acgtagccat ggaagcaagt
    14761 ctcaaactca aagagatttc ttatatccag tgtgaaggct ttgctgcagg agaactcaag
    14821 cacggaacca ttgccttgat tgaagaagga acgcctgttt tggctctctt gtcagatcca
    14881 gttcttgcca atcatactcg tggaaatatc caagaggtcg cagcccgtgg tgccaaagtc
    14941 ctcactatcg cagaagagaa tgtagccaaa gataccgacg atatcgtcct tacgaccgta
    15001 catccatacc tctcaccaat ttcaatggtc gtaccaacgc aattagtcgc ttactttgca
    15061 accctccacc gtggcctcga tgtggacaaa ccacgtaacc ttgccaagtc agtaacggta
    15121 gaataagcta aaaaagtcta gttatctagg cctttttctt gtgagcaaat tggttgcttg
    15181 tactcaagat tcgtgttata ctcttcgaaa atctcttcaa accacgtcaa cgtcgccttg
    15241 ccgtaggtat ggttactgac ttcgtcagtt ctatccacaa cctcaaaaca ctgttttgag
    15301 cagcctgcag ctagcttcct agtttgctct ttgattttca ttgagtatta gaataatttt
    15361 tcaaattgaa gtacagagat agataaggag aatcacaatg gtagaattgg gaatttcaac
    15421 atttggggaa ataacggagc ttgaagggac tggacaaact tacagtcatg ctgaacgcat
    15481 tcgccagttg gtggcagaga ttgagctggc tgacaaggtt ggtttggatg tatatgggat
    15541 tggtgagcac catcgggcgg attttgcagt atcagcccca gagattgttc tggccgctgg
    15601 ggcagtcaat accaagaaaa tccgtttgac cagtgcagtc agcattctgt caagcatgga
    15661 cccgattcgt ttgttccaac agtatgccac tatcgatgct ttgtcaaatg gacgagcgga
    15721 gattatggct ggaaggggct ctttcacgga atctttccct ctgtttggtt atgacttgaa
    15781 agactacgac tctctttttg atgagaaatt agacttgctt cagttagtca atgaaaagac
    15841 caagttagac tggcaaggtc gattgactca aacgattgct ggtaaagaag tttatcctcg
    15901 tccagttcag gacaaattgc ccttgtggat agctacaggt ggtcatgtcg aatcaacagt
    15961 gaagattgct caggctggtc taccgattgt atatgctatt attggtggta atccacgtta
    16021 ttttaaaaag ttgattcagg cttatcgtga gattggaagc gaagcgggtc atgctgacaa
    16081 agacttgaaa gtgggagccc attcttgggg gtggattgcg gaagatggtg agcaggcggt
    16141 gaaagattat ttccatccga ctaagcaagt ggtggatgct atttccaaag accgtccgca
    16201 ctggcaggaa ttgcgttatg agcaatattt ggagcaggta gggccaaatg gcgccatgtt
    16261 tgttggcaat ccagatcagg tggccgaaaa attgattcgc atgatagagg atttaggatt
    16321 ggaccgcttc atgcttcatc taccgcttgg ttctatgcct catgaccagg ttctgagagc
    16381 tattgaactc ttcggaacac aagttgcacc caaagtacga gcttattttg ctatgaaaga
    16441 ggcttaataa aaaatcctaa tcaagtttat taggacaaca aatattgtac gaaaattaat
    16501 cccccgagct ataatgcttg ggggattttt ctataggagg gctagtttag ttctcttttt
    16561 tattttttag taagaaaccg agaccaagga gcgcaaggag gctgattcct gcaaatagga
    16621 gtttgttttc gtttttgatt cctgtatttg gaagttcagc ttgtttatct ggggttacag
    16681 gtatattttt cttgctagag ttttctaccg attcgttttg aaccgcttct tttacagatg
    16741 atgcttgtgc ttcttgtgct ggttgttcag cttgtgaatc agctgtagct tggctaggtt
    16801 tattttccgc atcagctact ttggcatctg gtttagtaga atcaggtcta gcttctggag
    16861 ctgggtcttg atgttcaggc ttggaagggg ttgagtctgg tttctcttct gcagttgact
    16921 catggctagt tccattttga gagactcgaa gaacagtagc tgtaagggca ttcaatttca
    16981 agcctttttc agtccattca agtcctttcg ggttggcaat tccgactgat cctgcttggt
    17041 tttcatctgc caaaacttcc gcatttctta gatgtgcaaa ggcagttccc aaattaaatt
    17101 cgcgagcttt ttcatccgca ttgacaaaga ctgcgtagat atcgccgttt ggagcagtga
    17161 tttggtagcc aatcactaca tcctcttttt ccacaccatt ttggcctggg acagtgatga
    17221 ggtggacacg gtctttgata tcttggagac tcttaagtcg gaaggcatct gtagattgac
    17281 gaagggcaat caaacctttc atatagtcac ggctcttgac attttcagga taagctttac
    17341 catctgtagc cttagtccag tcaaacttgt tgactgcgtc gctagaatcg taagaatcat
    17401 ggatgaagta aggatagtca aatgggttgc cgtccttatc acgcaacaag tgagatttgt
    17461 ttggaacctt atcctctgct actggagtct tgtaggctgg gtcacggaat tgtttagtac
    17521 gtccatattc ctgaccggag tggataaatg gagttccttg agctgtcaag accatgagat
    17581 ttccaagtcg taaacgacgg tggatttcag catagttctc agccttgctt gggtcttttt
    17641 tgatagactg ggcaatgatg tcaaagaggg tcaagttatc atgggctgcg atgtattgga
    17701 tgacatctcc agggctgtca gcttcaaagt tagttggctg agcaatgaga tttttaaaga
    17761 tagtgttaac atcacgcttg ccacctgtga taaaggcagg ttgaccttcg tttggataac
    17821 cagatttgag gttgttacgg atgtcatctg aaaagacagc gacagtatcg gtatgtttca
    17881 tccaatcttg gtcagcagct ttagtaggca tgttttcatc accggcatag gttctccaac
    17941 cttcgcctaa catgattaga tttggattga gggcgcgtgc agccttgtaa gcttcttcga
    18001 tagaagcggc gtcatggtct cccatcatat cgaaacggaa tccatccact ttgtaggtat
    18061 caactaggta tttgatagag tcaactagga ggcgtttggt catatggtgg gttgtcccca
    18121 agcgtccacc accaaagcta gttcgaggtg tgccatcggc atccataaag tggtagtagt
    18181 ttggctctag gtcttcaaag atatcgactt tggctgtgtg gttataaacg acatctagga
    18241 tagctcccat accacgtttg tggatttcgt tgatgaggtt tttaaattct gcgattcgtt
    18301 tttctggatt cttaggatcg cttgagtaca taccagtcaa ggagaagtag ttttgagggt
    18361 catatcccca gttgtagttg ctgttgcttg aagcatagtc agacaagcgt tcatggtttt
    18421 tcaattcatt gacaaagtag taagacaaga ctggaaggag ctggatatgg gttacaccca
    18481 agtctttgag atagtctagt ttttcaatga aggcttcaaa agtcccaaat ggtttggtca
    18541 agtcttttgc aatggcagga tctgaagtga agtcacgcac atgagcttcg tagataacgg
    18601 cgtcttcacg agtcttgaaa ttgtgaatct taccataagt caagtcttga ggtccgagtt
    18661 tagctggatc tacaaaggcg gctttagcca ctttatgggc atcgtcaatc ttggcatcgt
    18721 cgctattcca agcagcaaga gatttagcgt aaggatcgag tgcaagaaca gttttacctt
    18781 gacgctcgat ttggtattga taatagtagc cagtgaaatc tgtgattccg agtttgtttg
    18841 tgctgtctag agtttgtttc caagttcctc tttccccttt ttcgagagcg acagttccaa
    18901 ctactttgtc agggtcattc ttgtcgtaga caacaacaga aaccttatca gcacttggtg
    18961 accaaagggt caaatcaact tgttttcctt cttcttttag gtcagctccc agtttgccat
    19021 catagctgta tgtctcatct ttcaggcgcc agcttgtttt ggtagtgaat tggtcggaat
    19081 tgtagctaac agtataagga tgttttgtgt cagagaaatc tccgctgtag gtcactttct
    19141 taccagcttc atcgattgca acatcggtaa tagttacctt gtttcctagg tgattagtga
    19201 tgttggagtg tttgaggata tcttcttttt tagcaccgac aagtgttgaa aagctacttt
    19261 caatgctaga agtgcctacg tgttgggctc ctgtcatacg gatatcatgg acatagtatg
    19321 gatttgtgta aatcgattca tcatcgtctt ttaggaaaat ttggctatga tttttcaaat
    19381 ctgtgaactt ataattttct ttacggattt tcacgtcgtc tccttgtttg ctctcatcta
    19441 gtaataaaaa tccaaattct cttgcggctt cattaagagg aatgtcgata tagcggccat
    19501 atttgcctgt agccgtaaag tctgttccgt caggccattg agcgctactt ggatttttta
    19561 catctcccca gtaccagaga gatttcttgt catagttgcc atctgtgcgg tagtagttga
    19621 cgcgaacagt tcctgcaggc tgtggctcgt aagagaaaac cttgtaatct tggtctaacc
    19681 aagcttcgtt catttttgga actagttttt ctacagattt atcgccggtt agattttttc
    19741 cagctgtatt gttgatgagg aagctaattt tcttggcttg ttctcccttt aatttgacat
    19801 ctaggtaata gccgtagtca tctttcttgg catccttgaa ggacaaagct ccgtttggcc
    19861 agttttcaga tggtttttca acatcgtccc aagtccatag tccttgagca tccttgtttt
    19921 cttcaggaag ttttttgaca tggatacgga agtagttatc ttcgatgggc tcttctgcct
    19981 tagtttcagt tgttactgga ctagtagaag tagttggctc tgttgcaggt ttttcttctg
    20041 ttttctctag ggaagcgttt gcatttctag gtgaagaaat atcactttcg ttcttaccag
    20101 agccagctgc tgtatcagta agaggttggg caagggtggt tgtatttctg ttgttgggtt
    20161 cgttagtggt tggtgtactt tcgtcggatg agatagttgg tgtagccatg gcaagcaaga
    20221 caaggcttgc gccgataagg acagaaccag ttccattttt gagggaacgg atgctgtaga
    20281 ccattttttt ctcagtgtga gatggtgttt ttctcataat gattctccaa tcaataaatt
    20341 tctatatcag tatagcatgt agtaaaacaa tatgcaagcg ttttctttga tttgtgaaaa
    20401 aaattcctac ttttgagaag ttttctgtac tattttatat atcagtataa atgacggaga
    20461 taaaaatgtc acataagcca agccgtatta ttaggaagat gatgtgttcc cagctatttt
    20521 tattcagaaa ttgatctcta acattaccaa taaaaatgaa aaatatcttg acaagcaagg
    20581 gaaaattttg ttacaataat agacggtact ttttactttt ggtctctcaa gagtgtacag
    20641 ggacgtgctg acaaatgttg caaaagtaca cacagatgat atctgtcacc aagtgtatca
    20701 tcaccaaaaa taaaaaaaca caggagaatg tagatgccta caattaacca attggttcgc
    20761 aaaccgcgta aatcaaaagt agaaaaatct aaatcaccag ctttgaacgt tggttacaat
    20821 agtcataaaa aagttcaaac aaacgtttct tcaccacaaa aacgtggtgt tgcaactcgt
    20881 gttggaacaa tgacacctaa aaaacctaac tcagcccttc gtaaattcgc tcgtgtacgt
    20941 ttgagcaacc ttatcgaagt tactgcctac atcccaggta tcggacacaa cttgcaagag
    21001 cacagcgtgg tgcttcttcg cggtggacgt gtaaaagacc ttccaggggt acgttaccat
    21061 atcgtccgtg gtgcacttga tactgcaggt gttaacgatc gtaaacaagg ccgttctaaa
    21121 tacggtacta aacgtccaaa agcataagga aaggggataa agagaaatga gtcgtaaaaa
    21181 tagagctcca aaacgtgacg tattgccaga tccgctatac aattcacaac tagttactcg
    21241 tcttatcaac cgcgttatgc ttgatggtaa acgtggtact gctgcttcaa tcgtttacgg
    21301 tgcttttgag caaatcaaag aagctactgg caacgatgca cttgaagtat ttgaaacagc
    21361 tatggaaaac atcatgcctg tacttgaagt acgtgcacgt cgtgttggtg gttctaacta
    21421 ccaagtccca gttgaagttc gtccagaacg tcgtacaaca cttggacttc gttggttggt
    21481 aacaatcgct cgtcttcgtg gtgaacacac aatgcaagac cgtcttgcaa aagaaatctt
    21541 ggatgctgct aacaacactg gtgcagcagt taagaaacgt gaagatactc accgtatggc
    21601 tgaagctaac cgtgcattcg cacacttccg ttggtaagat aggatgcgaa agcgttaaga
    21661 aagtcccaga gaaaataggg aatcgaagca ggttgcggtt gcaaccaatg agattcatct
    21721 ttttctccag acttttagct tgagctcaac taaatcatga tgctaggcac ggtaaggatg
    21781 caaggtgaaa ataggaaact gacgcagtat tcaacgaata caaggagttt tatctttttc
    21841 acgcagcatc ccgttccagc tcacatcggc taactaactt tagcctgggt tcaaattagc
    21901 taaatcgatt agtattagct ataactcagc ttaccatctc gtaagttgaa accaacaata
    21961 gcatgaaaac attgagaacg ggtaggtcct gcctatccgt ttttattaaa atcgtgttat
    22021 aatagaatag aaatcaaaaa taaataggag aaacaaacct catggcacgc gaattttcac
    22081 ttgaaaaaac tcgtaatatc ggtatcatgg ctcacgtcga tgccggtaaa acaacaacta
    22141 ctgagcgtat tctttactac actggtaaaa tccacaaaat cggtgaaact cacgaaggtg
    22201 cgtcacaaat ggactggatg gagcaagagc aagaacgtgg tatcacgatc acatctgctg
    22261 cgacaacagc tcaatggaac aaccaccgcg taaacatcat cgacacacca ggacacgtgg
    22321 acttcacaat cgaagtacaa cgttctcttc gtgtattgga tggtgcggtt accgttcttg
    22381 actcacaatc aggtgttgaa cctcaaactg aaacagtttg gcgtcaagca actgagtacg
    22441 gagttccacg tatcgtattt gccaacaaaa tggacaaaat cggtgctgac ttcctttact
    22501 ctgtaagcac acttcacgat cgccttcaag caaatgcaca cccaatccaa ttgccaatcg
    22561 gttctgaaga tgacttccgt ggtatcattg acttgatcaa gatgaaagct gaaatctata
    22621 ctaacgacct tggtacggat atccttgaag aagacatccc agctgaatac cttgaccaag
    22681 ctcaagaata ccgtgaaaaa ttggttgaag cagttgctga aactgacgaa gaattgatga
    22741 tgaaatacct cgaaggtgaa gaaattacta acgaagaatt gaaagctggt atccgtaaag
    22801 cgactattaa cgttgaattc ttcccagtat tgtgtggttc agccttcaag aacaaaggtg
    22861 ttcaattgat gcttgatgcg gttattgact accttccaag cccacttgac atcccagcaa
    22921 tcaaaggtat taacccagat acagatgctg aagaaactcg tccagcatct gacgaagagc
    22981 catttgcagc tcttgccttc aagatcatga ctgacccatt cgtaggtcgt ttgacattct
    23041 tccgtgttta ctcaggtgtt cttcaatcag gttcatacgt attgaacact tctaaaggta
    23101 aacgtgaacg tatcggacgt attcttcaaa tgcacgctaa cagccgtcaa gaaattgaaa
    23161 ctgtttactc aggtgatatc gctgctgccg ttggtttgaa agatactaca actggtgact
    23221 cattgacaga tgaaaaagct aaaatcatcc ttgagtcaat caatgttcca gaaccagtta
    23281 tccaattgat ggttgagcca aaatctaaag ctgaccaaga caagatgggt atcgcccttc
    23341 aaaaattggc tgaagaagat ccaacattcc gcgttgaaac aaacgttgaa actggtgaaa
    23401 cagttatctc tggtatgggt gagcttcacc ttgacgtcct tgttgaccgt atgcgtcgtg
    23461 agttcaaagt tgaagcgaac gtgggtgctc ctcaagtatc ttaccgtgaa acattccgcg
    23521 cttctactca agcacgtgga ttcttcaaac gtcagtctgg tggtaaaggt caattcggtg
    23581 atgtatggat tgaatttact ccaaacgaag aaggtaaagg attcgaattt gaaaacgcaa
    23641 tcgtcggtgg tgtggttcct cgtgaattta tcccagcagt tgaaaaaggt ttggtagaat
    23701 ctatggctaa cggtgttctt gcaggttacc caatggttga cgttaaagct aaactttacg
    23761 atggttcata ccacgatgtc gactcatctg aaactgcctt caagattgcg gcttcacttg
    23821 ctcttaaaga agctgctaaa tcagcacaac cagcgatcct tgagccaatg atgcttgtaa
    23881 caatcactgt tccagaagaa aaccttggtg atgttatggg tcacgtaact gctcgtcgtg
    23941 gacgtgtaga tggtatggaa gcacatggta acagccaaat cgttcgtgct tacgttccac
    24001 tcgctgaaat gttcggttac gcaacagttc ttcgttctgc atctcaagga cgtggtacat
    24061 tcatgatggt atttgaccac tacgaagatg tacctaagtc agtacaagaa gaaatcatta
    24121 agaaaaacaa aggtgaagac taatcagtcc tcactctaga aggaagtcac ttagtggctt
    24181 ccttttgtct ttagaaaata cctctaaata tggtaaaata gtagaagaat aatgtgagga
    24241 aaatgaatgt caaatagttt tgaaattttg atgaatcaat tggggatacc tgttgaaatg
    24301 agacagcatc ctgctttaac acaggcagat attgagcgag tcgtggttca taaaattagt
    24361 aaggtatggg agtttcattt cgtattttct aatattttac cgattgaaat ctttttagaa
    24421 ttaaagaaag ggctgagtga ggaattttct aagacaggca ataaagctgt tttcgaaatc
    24481 aaggttctgt ctcaagattt ttcaaatcaa ctcttgcagg cttattatag agaagctttt
    24541 tctgagggtc catgtgctag tcaaagtttt aagtctcttt atcaaaattt gcaagttcgt
    24601 gctgagggga atcaactctt tattgaagga tctgaggcga ttgataagga acactttaag
    24661 aaaaatcacc ttcctaattt agcaaaacaa cttgaaaagt ttggttttcc aacttttaac
    24721 tgtcaggtcg agaagaatga tgtgctgacc caagagcagg aagatgcctt ccatgctgaa
    24781 aatgagcaga ttgttcaagc ggccaatgag gaagcgctcc gtgctatgga acaactagaa
    24841 cagatggcgc cacctccagc ggaagagaaa ccagcctttg attttcaaac gaaaaaagct
    24901 gcagctaaac ccaagctaga taaggcggag attactccta tgatcgaagt gacgacggag
    24961 gaaaatcgtc tggtctttga aggggttgtg tttgatgtgg agcaaaaagt gaccagaaca
    25021 gggcgtgttt tgatcaactt taaaatgacg gactacactt caagtttttc gatgcaaaag
    25081 tgggtaaaaa atgaggaaga ggctcagaaa tttgatctca tcaagaagaa ttcttggctc
    25141 cgagttcgtg ggaatgtgga gatgaataac ttcacacgcg atttgactat gaatgtgcag
    25201 gatgtgcagg aagttgttca ctatgagcgg aaggatttga tgccagaagg tgagcgtcgg
    25261 gttgagtttc acgctcatac taacatgtcg actatggatg ctctaccaga ggttgaagaa
    25321 atcgttgcta cagctgctaa gtggggacac aaagcagttg ctatcaccga ccacgggaat
    25381 gttcaatcct tcccacacgg ctataaggcg gctaagaaag cgggaatcca gctaatctat
    25441 gggatggaag ccaatatcgt ggaggaccgt gtccctatcg tctataacga agtggagagg
    25501 gacttgtcag aagcgaccta cgtggtcttt gacgtggaaa cgacgggtct atcagccatc
    25561 tataatgatt tgattcaggt tgcggcctct aagatgtaca aggggaatgt cattgctgaa
    25621 tttgatgaat ttatcaatcc tgggtatccc ttgtcagctt ttactactga gttgactgga
    25681 attacagatg atcacgtcaa aaatgccaaa ccactagaac aagttctgca agaattccaa
    25741 gaattctgca aggatacggt cctagttgcc cacaatgcga cctttgacgt tggctttatg
    25801 aatgccaact atgagcgtca tggtcttcct aaaattagcc agccagttat tgatacgctg
    25861 gagtttgcta gaaacctcta tcctgagtat aaacgtcatg gtttggggcc tttgactaag
    25921 cgttttggtg tggctttgga acatcaccac atggccaatt acgatgcgga agctactggt
    25981 cgtctgctct ttatttttat caaagaagta gcagaaaaac atggagtgac cgatctagct
    26041 agactcaaca ttgatttgat tagtccagat tcttataaaa aagctcggat caagcatgcg
    26101 actatttatg tcaagaatca ggtaggtcta aaaaatatct ttaagctagt ttctttgtcc
    26161 aatactaagt actttgaagg ggtgccacga attccgagaa cagttctaga tgcccatcgg
    26221 gaaggtttga ttttaggttc agcttgctct gaaggtgaag tttttgatgc ggttgtttcc
    26281 caaggtgtgg atgcggcggt tgaggtggcc aagtattatg actttatcga ggtcatgcca
    26341 ccagctatct atgctccctt gattgccaag gagcaggtca aggatatgga agaactccag
    26401 actattatca agaatttgat agagatcggc gaccgtcttg gcaagcccgt tttggctacg
    26461 ggaaatgtcc actatatcga accagaagaa gaaatttacc gtgaaattat cgtccgcagt
    26521 ttgggtcagg gggcgatgat taaccgaacc atcggtcatg gtgaacatgc ccaaccagca
    26581 ccacttccaa aggctcattt tagaacgact aatgagatgt tggatgaatt tgccttcttg
    26641 ggagaggaac tagcccggaa attggttatt gaaaacacca atgccttggc agaaatcttt
    26701 gaacccgttg aggtagttaa gggtgacttg tatacgcctt tcattgacaa ggctgaagaa
    26761 acagttgctg agttgaccta taagaaagct tttgagattt atggaaatcc gttgccagat
    26821 attgttgatt tgcgaattga aaaagaattg acttccattc tggggaatgg atttgctgtg
    26881 atttatctgg catcgcagat gctggttcaa cgttccaatg aacggggtta cctggtgggt
    26941 tctcgtgggt ctgtaggatc tagtttcgtt gcgactatga ttggtattac ggaggttaat
    27001 cctctctctc ctcactatgt ctgtggtcag tgtcaataca gcgagtttat caccgatggt
    27061 tcttatggtt caggttttga tatgcccaat aaggactgtc caaactgcgg tcacaaactc
    27121 agtaaaaacg gacaggatat tccgtttgag accttccttg gctttgatgg ggataaggtt
    27181 cctgatattg acttgaactt ctcgggagaa gatcagccta gcgcccactt ggatgtgcgt
    27241 gatatctttg gtgaagaata tgccttccgt gcgggaacgg ttggtacggt agctgccaag
    27301 actgcctatg gatttgtcaa gggttacgag cgagattatg gcaagtttta tcgtgatgca
    27361 gaagtagaac gcctcgctca aggagcggcg ggtgtcaagc ggacaacagg ccaacacccg
    27421 gggggaatcg ttgttattcc gaactacatg gatgtctacg attttacgcc tgtccagtat
    27481 ccagcagatg atgtcacggc tgaatggcag accactcact ttaacttcca cgatatcgat
    27541 gagaacgtcc tcaaactcga tgtactggga catgatgatc cgaccatgat tcgaaaactt
    27601 caggatttgt ctggtattga ccctaatgaa attcctatgg atgacgaagg cgtgatggca
    27661 ctcttttctg ggactgatgt gctaggggta acacctgaac aaattggaac gcctacgggt
    27721 atgttgggga ttccagagtt tggaacaaat ttcgtacgtg gaatggtaga cgaaacccat
    27781 ccgacaacct ttgcggaatt gcttcagctg tctggtctgt cccacggtac tgacgtttgg
    27841 ttggggaatg ctcaggatct gattaagcaa ggaatagcgg acctatcgac tgttatcggt
    27901 tgtcgggacg acatcatggt ttacctcatg catgcgggtc tggaacctaa gatggccttt
    27961 accattatgg aacgggtacg taagggtttg tggctaaaga tttcagaaga ggagagaaat
    28021 gactatatcg aagccatgaa ggccaataag gtgccagagt ggtatatcga atcctgtggg
    28081 aaaattaagt acatgttccc taaggcccat gcggcagcct acgttatgat ggccttgcgt
    28141 gtagcttact tcaaggttca ccatcctatt tattactact gtgcttactt ctccattcgt
    28201 gctaaggctt ttgatatcaa gaccatgggt gcgggcttgg aggtcatcaa gcgcagaatg
    28261 gaagaaatct ctgaaaaacg gaagaacaat gaagcctcta atgtggaaat cgatctctat
    28321 acaactcttg agattgtcaa tgagatgtgg gaacgaggtt tcaagtttgg caaattagat
    28381 ctctaccgta gtcaggcgac agagttcctc atcgacgggg atacccttat cccaccattt
    28441 gtagcaatgg atggtctggg agagaacgtt gccaagcaac tggtgcgggc gcgtgaagag
    28501 ggagaattcc tctctaaaac agaactacgc aagcgtggtg gactctcatc aaccttggtt
    28561 gaaaagatgg atgagatggg tattcttgga aatatgccag aggataacca gttgagtttg
    28621 tttgatgagt tgttttaaaa aattgcttaa taatctatta aaagaggcta acgtatatcc
    28681 aatagattta cattagcttt cttttttgtt aaaatagtct atggaaagag ggtgagagta
    28741 tgtcaaagat gagtataagc atccgtctgg atagtgaggt taaggagcag gcccaacagg
    28801 tgtttagtaa tctgggaatg gatatgacaa cagctattaa tattttcctt cgtcaggcaa
    28861 ttcaatatca gggattacct tttgatgtta gactagacga aaatcggaag ttgctccaag
    28921 cgttaacgga tttagaccaa aatcgtaata tgagccagtc ttttgaatca gtctcagatt
    28981 tgatggagga cttacgtgct taagattcgt tatcataaac agtttaaaaa agattttaag
    29041 ttggctatga agcgtggttt gaaggcagaa ttattagaag aagttttgaa ttttctggtt
    29101 caagaaaaag aacatcctgc cagatatcgt gatcattcat tgacggcatc caagcatttt
    29161 caaggagttc gtgaatgcca tacccagcca gattggcttt tggtttataa agtagacaag
    29221 tcggaattga ttttaaattt gctgaggaca ggcagtcaca gtgatttatt ttaatctatt
    29281 ttaagggggt tctcatgaaa ctaagaatat ttgcggaaga taagccggct aagaaggtat
    29341 ttgaatatca attagaactt gctgatcgta caattcttct atcgacagca ctcttgtcag
    29401 gtgctattgc tttagcagga atcttttctg ctttgagaga aaaataaaaa tagaaaagag
    29461 aaaacagaat ggttttacca aattttaaag aaaatctaga aaaatatgcg aaattgttgg
    29521 ttgcgaacgg aattaacgtg caacctggtc acactttggc tctttctatt gatgtggagc
    29581 aacgtgaatt ggcacatcta atcgtgaaag aagcttatgc cttgggtgcg catgaggtca
    29641 tcgttcagtg gacagatgat gtgattaacc gtgagaaatt cctccatgcc ccgatggagc
    29701 gtttggacaa tgtgccagaa tacaagattg ctgagatgaa ctatctcttg gagaacaagg
    29761 ctagccgtct tggagttcgt tcatctgatc caggtgcctt gaacggagtg gacgctgaca
    29821 agctttcagc ttctgctaaa gctatgggac ttgccatgaa gcctatgcgt atcgcaactc
    29881 aatctaacaa ggttagctgg actgtagcag ctgcagcagg acttgagtgg gctaagaaag
    29941 tcttcccaaa tgctgcgagc gacgaagaag cagttgattt cctttgggac caaattttca
    30001 aaacttgccg tgtctacgaa gcagatcctg ttaaggcttg ggaggaacat gcagccattc
    30061 tcaagagcaa ggccgatatg cttaataagg agcaattttc agcccttcac tacacagcgc
    30121 caggaacaga tttaacactt ggtttgccaa agaaccacgt ttgggaatca gctggtgctg
    30181 tcaatgcaca gggcgaagaa ttcttgccaa atatgccaac agaagaggtc ttcacagcgc
    30241 ctgacttccg tcgtgcagat ggttatgtca cttctacaaa accgcttagc tacaacggaa
    30301 atatcattga aggcattaag gtgaccttta aggatggaca aatcgtagat atcactgctg
    30361 agaagggtga tcaggttatg aaagaccttg tctttgaaaa tgcgggtgcg cgtgccttgg
    30421 gtgaatgtgc cttggtacca gatccaagtc caatttctca gtcaggcatt accttcttta
    30481 acaccctttt cgatgaaaat gcgtcaaacc acttggctat cggtgcagcc tatgcgacta
    30541 gcgttgttga tggagcggag atgagcgaag aggagcttga agctgcaggg cttaaccgtt
    30601 cagatgttca cgtagacttt atgattggtt ctaaccaaat ggatatcgat ggtattcgtg
    30661 aggatggaac gcgggtacct cttttccgta atgggaattg ggcaaattaa ggagataata
    30721 tgttaggaag tatgttcgtt ggtctcctag tgggattttt agcaggtgct atgaccaatc
    30781 gtggagagcg aatgggatgt tttggaaaaa tgtttctcgg ttggatcgga gcctttctag
    30841 gtcacttgct ctttggaact tgggggccag ttttatcagg aacagctatt atcccagcga
    30901 ttttaggagc catgattgtt ttagctattt tttggagacg aggaagttaa tttcctaaat
    30961 ct
//
LOCUS       DAVBOD010000020        27330 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 640-05
            SAMEA1012484-rid20186543.denovo.020, whole genome shotgun sequence.
ACCESSION   DAVBOD010000020 DAVBOD010000000
VERSION     DAVBOD010000020.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012484
            Sequence Read Archive: ERR059358
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 27330)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27330)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979948.1
            Genome Coverage       :: 595x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:03:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,266
            CDSs (total)                      :: 2,219
            Genes (coding)                    :: 2,091
            CDSs (with protein)               :: 2,091
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 71 of 128
            Pseudo Genes (incomplete)         :: 50 of 128
            Pseudo Genes (internal stop)      :: 33 of 128
            Pseudo Genes (multiple problems)  :: 22 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27330
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012484-rid20186543.denovo.020"
                     /strain="NIG 640-05"
                     /db_xref="taxon:1313"
     gene            complement(<1..137)
                     /locus_tag="VQ862_001000"
     CDS             complement(<1..137)
                     /locus_tag="VQ862_001000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000389281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET3115365.1"
                     /translation="MEDFFAWCRRQSVLAGSKLGRAIEYSLKYKETFKTILKDGHLVL
                     S"
     gene            complement(436..1212)
                     /locus_tag="VQ862_001001"
                     /pseudo
     CDS             complement(436..1212)
                     /locus_tag="VQ862_001001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000457791.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(1136..1330)
                     /locus_tag="VQ862_001002"
     CDS             complement(1136..1330)
                     /locus_tag="VQ862_001002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET3115366.1"
                     /translation="MKIIQQQSATIDSLTNELALLREQVAYLTQKLYGKSSEKSVCPS
                     GQLSLFEEEQNMEEDSDLPS"
     gene            complement(1500..1850)
                     /gene="tnpB"
                     /locus_tag="VQ862_001003"
                     /pseudo
     CDS             complement(1500..1850)
                     /gene="tnpB"
                     /locus_tag="VQ862_001003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846105.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
     gene            complement(1831..2016)
                     /locus_tag="VQ862_001004"
     CDS             complement(1831..2016)
                     /locus_tag="VQ862_001004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001136123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3115367.1"
                     /translation="MPQPIVPVEIPQSRPFDSKKRNDILLKIRIGKLEVSFFQSLNLE
                     MVEQLLDKVLLYDNSSI"
     gene            complement(2320..3882)
                     /gene="guaA"
                     /locus_tag="VQ862_001005"
     CDS             complement(2320..3882)
                     /gene="guaA"
                     /locus_tag="VQ862_001005"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000065723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HET3115368.1"
                     /translation="MSNISTDLQDVEKIIVLDYGSQYNQLISRRIRDIGVFSELKSHK
                     ISAAEVREVNPVGIILSGGPNSVYEDGSFDIDPEIFELGIPILGICYGMQLLTHKLGG
                     KVVPAGDAGNREYGQSTLTHTPSALFESTPDEQTVLMSHGDAVTEIPADFVRTGTSAD
                     CPYAAIENPDKHIYGIQFHPEVRHSVYGNDILRNFALNICKAKGDWSMDNFIDMQIKK
                     IRETVGDKRVLLGLSGGVDSSVVGVLLQKAIGDQLICIFVDHGLLRKGEADQVMDMLG
                     GKFGLNIVKADAAKRFLDKLAGVSDPEQKRKIIGNEFVYVFDDEASKLKDVKFLAQGT
                     LYTDVIESGTDTAQTIKSHHNVGGLPEDMQFELIEPLNTLYKDEVRALGTELGMPDHI
                     VWRQPFPGPGLAIRVMGEITEEKLETVRESDAILREEIAKAGLDRDIWQYFTVNTGVR
                     SVGVMGDGRTYDYTIAIRAITSIDGMTADFAKIPWEVLQKISVRIVNEVDHVNRIVYD
                     ITSKPPATVEWE"
     gene            4024..4722
                     /locus_tag="VQ862_001006"
     CDS             4024..4722
                     /locus_tag="VQ862_001006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000936186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HET3115369.1"
                     /translation="MLPAYMKIHDQIKKDIDEHRWAIGERLPSERDLAEQFAVSRMTL
                     RQAVSLLVEEGVLERHVGSGTFVSSTRVQEKMRGTTSFTEIVKSQGKVPSSQLISYKK
                     TIPNEQEVAKLGIFPTDNIIRMERVRYADQVPLVYEVASIPEKFIKDFKKEEITSHFF
                     QTLQKHGYRIGKSQQTIYARLAKEKIAHYLEVEKGHAILGLTQVSYLEDGTAFEYVKS
                     QYVGERFEFYLENN"
     gene            complement(4765..5661)
                     /locus_tag="VQ862_001007"
     CDS             complement(4765..5661)
                     /locus_tag="VQ862_001007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000071673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EamA family transporter"
                     /protein_id="HET3115370.1"
                     /translation="MSNSLKGTLLTVVAGIAWGLSGTSGQYLMAHGISALVLTNLRLL
                     IAGGILMLLAYATAKDKILVFLKDRKSLLSLLIFALIGLFLNQFAYLSAIQETNAGTA
                     TVLQYVCPVGILIYSCIKDRVAPTLGEIVSIIFAIGGTFLIATHGQLDQLSMTPAGLF
                     WGLFSAFTYALYIILPIALIKKWGSSLVIGVGMVIAGLVALPFTGVLQADIPTSLDFL
                     LAFAGIILIGTVFAYTAFLKGASLIGPVKSSLLASIEPISAIFFAFLIMNEQFYPIDF
                     LGMAMILFAVTLISLKDLFLEK"
     gene            complement(5670..6605)
                     /locus_tag="VQ862_001008"
     CDS             complement(5670..6605)
                     /locus_tag="VQ862_001008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000872223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-lactamase family protein"
                     /protein_id="HET3115371.1"
                     /translation="MKWTKIIKKIEEQIEAGIYPGASFAYFKDNQWTEFYLGQSDPEH
                     GLQTEAGLVYDLASVSKVVGVGTVCTFLWEIGQLDIDRLVIDFLPESDYPDITIRQLL
                     THATDLDPFIPNRDLLTAPELKEAMFHLNRRSQPAFLYSDVHFLLLGFILERIFNQDL
                     DVILKDQVWKPWGMTETKFGSVELAVPTVRGVEAGIVHDPKARLLGRHAGSAGLFSTI
                     KDLQIFLEHYLADDFARDLSQNFSPLDDKERSLAWNLEGDWLDHTGYTGTFIMWNRQK
                     QEATIFLSNRTYEKDERAQWILDRNQVMNLIRKEE"
     gene            complement(6602..7327)
                     /locus_tag="VQ862_001009"
     CDS             complement(6602..7327)
                     /locus_tag="VQ862_001009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001102210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CppA family protein"
                     /protein_id="HET3115372.1"
                     /translation="MNVNQIVRIIPTLKANNRKLNETFYIETLGMKALLEESAFLSLG
                     DQTGLEKLVLEEAPSMRTRKVEGRKKLARLIVKVENPLEIEGILSKTDSIHRLYKGQN
                     GYAFEIFSPEDDLILIHAEDDRASLVEVGEKPEFQTDLVSISLSKFEISMELHLPTDI
                     ESFLESSEIGASLDFIPAQGQDLTVDNTVTWDLSMLKFLVNELDIASLRQKFESTEYF
                     IPKSEKFFLCKDRNNVELWFEEV"
     gene            complement(7411..8046)
                     /locus_tag="VQ862_001010"
     CDS             complement(7411..8046)
                     /locus_tag="VQ862_001010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-alkyl-2-acetylglycerophosphocholine esterase"
                     /protein_id="HET3115373.1"
                     /translation="MAVQLLENWLLKEQEKIQTKYRHLNHISVVEPNILFIGDSIVEY
                     YPLQELFGTSKTIVNRGIRGYQTGLLLENLDAHLYGGAVDKIFLLIGTNDIGKDVPVN
                     EALNNLEAIIQSVARDYPLTEIKLLSILPVNEGEEYQQAVYIRSNEKIQNWNQAYQEL
                     ASAYMQVEFVPVFDCLTDQAGQLKKEYTTDGLHLSIAGYQALSKALKDYLY"
     gene            complement(8048..8875)
                     /locus_tag="VQ862_001011"
     CDS             complement(8048..8875)
                     /locus_tag="VQ862_001011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HET3115374.1"
                     /translation="MMIKVIATDMDGTLLDARGQLDLPRLEKILDQLDQRGIRFVIAT
                     GNEIHRMRQLLSPLVDRVVLVVANGARIFENNELIQAQTWDDAIVNKALTHFKGRACQ
                     DQFVVTGMKGDFVKEGTIFTDLESFMTPEMIEKFYQRMQFVDELTSDLFGGVLKMSMV
                     VGEERLSSVLEEINALFDGRVRAVSSGYGCIDILQAGIHKAWGLEELLKRWDLKSQEI
                     MAFGDSENDVEMLEMAGIAYAMENADEKAKAVATALAPANSQGGVYQVLENWLEKGE"
     gene            complement(8897..9232)
                     /locus_tag="VQ862_001012"
     CDS             complement(8897..9232)
                     /locus_tag="VQ862_001012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="poly-gamma-glutamate biosynthesis protein"
                     /protein_id="HET3115375.1"
                     /translation="MGNFISNQRIESMGDEENAKWTERGVLMDVTIKKKDGKTTIGTA
                     KAHPTWVNRTPKGTFSPEGYPLYHYQTYILEDFIEDGSHRDQLDEATKERIDTAYKEM
                     NEHVGLKWY"
     gene            complement(9233..9764)
                     /locus_tag="VQ862_001013"
                     /pseudo
     CDS             complement(9233..9764)
                     /locus_tag="VQ862_001013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864593.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="CapA family protein"
     gene            10395..11006
                     /locus_tag="VQ862_001014"
     CDS             10395..11006
                     /locus_tag="VQ862_001014"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015058782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HET3115376.1"
                     /translation="MSAIERITKAAHLIDMNDIIREGNPTLRAIAEEVTFPLSDQEII
                     LGEKMMQFLKHSQDPVMAEKMGLRGGVGLAAPQLDISKRIIAVLVPNIVEEGETPQEA
                     YDLEAIMYNPKIVSHSVQDAALGEGEGCLSVDRNVPGYVVRHARVTVDYFDKDGEKHR
                     IKLKGYNSIVVQHEIDHINGIMFYDRINEKDPFAVKDGLLILE"
     gene            11051..11779
                     /gene="rlmB"
                     /locus_tag="VQ862_001015"
     CDS             11051..11779
                     /gene="rlmB"
                     /locus_tag="VQ862_001015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (guanosine(2251)-2'-O)-methyltransferase RlmB"
                     /protein_id="HET3115377.1"
                     /translation="MKTNDIVYGVHAVTEALLANTGNKLYLQEDLRGKNVEKVKELAT
                     EKKVSISWTSKKSLSEITEGAVHQGFVLRVSEFAYSELDYILAKTRQEENPLLLILDG
                     LTDPHNLGSILRTADATNVSGVIIPKHRAVGVTPVVAKTATGAIEHVPIARVTNLSQT
                     LDKLKDEGFWTFGTDMNGTPCHKWNTKGKIALIIGNEGKGISSNIKKQVDEMITIPMN
                     GHVQSLNASVAAAILMYEVFLNRL"
     gene            complement(11818..12729)
                     /gene="trxB"
                     /locus_tag="VQ862_001016"
     CDS             complement(11818..12729)
                     /gene="trxB"
                     /locus_tag="VQ862_001016"
                     /EC_number="1.8.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-disulfide reductase"
                     /protein_id="HET3115378.1"
                     /translation="MYDTIIIGAGPAGMTAALYAARSNLKVALIEGGLPGGQMNNTSD
                     IENYPGYANISGPELAEKMFEPLENLGVEHIYGYVENVEDHGDFKKVMTDDQTYETRT
                     VIVATGSKHRPLGVPGEEELNSRGVSYCAVCDGAFFRDQDLLVVGGGDSAVEEALFLT
                     RFAKTVTIVHRRDQLRAQKVLQDRAFANEKISFIWDSVVKEIKGENRVESVVFENVKT
                     GQVTEQAFGGVFIYVGLDPLSDFVKELNIQDQAGWIVTDSHMKTAVDGIFAVGDVRLK
                     DLRQVTTAVGDGAIAGQEAYKFITEHS"
     gene            complement(12795..13019)
                     /locus_tag="VQ862_001017"
     CDS             complement(12795..13019)
                     /locus_tag="VQ862_001017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000924294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4059 family protein"
                     /protein_id="HET3115379.1"
                     /translation="MLLQLFSLYFESLILTTILVLIFLGIWIGLRAMSGVDKTARARQ
                     AHLYDMIMIGVLVVPVLSFAVMSLILVFKA"
     gene            complement(13097..13840)
                     /locus_tag="VQ862_001018"
     CDS             complement(13097..13840)
                     /locus_tag="VQ862_001018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HET3115380.1"
                     /translation="MIKISNLSKSFSGQTVLDHLNLDIQKGEVVALIGSSGAGKSTFL
                     RSLNYLETPDSGSIQIDGFSVDFSKITQEEILALRRKLSMVFQQFNLFERRTALDNVK
                     EGLVVVKKLSDQEATKIAKEELAKVGLSDRENHYPRHLSGGQKQRVALARALAMKPDV
                     LLLDEPTSALDPELVGEVEKSIADAAKSGQTMILVSHDMSFVAQVADKILFLDKGKII
                     ESGTPDEIIHTPKEERTKEFFASYKRTYI"
     gene            complement(13840..14640)
                     /locus_tag="VQ862_001019"
     CDS             complement(13840..14640)
                     /locus_tag="VQ862_001019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001103446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HET3115381.1"
                     /translation="MNVTTILASDWYQNLMQLIPDGKLFSLRSVFDGIPRIVQQLPTT
                     IMLTIGGALFGLVLALLFAIVKINRVKILYPLQAFFVSFLKGTPILVQLMLTYYGIPL
                     ALKALNQQWGTGLNINAIPAAAFAIVAFAFNEAAYASETIRAAILSVNPGEIEAARSL
                     GMTRAQVYRRVIIPNAAVVATPTLINSLIGLTKGTSLAFSAGVVEVFAQAQILGGADY
                     RYFERFISVALVYWVVNIGIESLGRFIERKMAISAPDTVQTDVKGDLR"
     gene            complement(14798..15154)
                     /locus_tag="VQ862_001020"
     CDS             complement(14798..15154)
                     /locus_tag="VQ862_001020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000889075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HET3115382.1"
                     /translation="MLEFIEYPKCSTCKKAKQELNQLGVDYKAVHIVEETPSQEVILN
                     WLETSGFELKQFFNTSGIKYRELGLKDKVGSLSNQEAAELLASDGMLLKRPILVENGT
                     VKQIGYRKSYEELGLK"
     gene            complement(15167..15679)
                     /locus_tag="VQ862_001021"
     CDS             complement(15167..15679)
                     /locus_tag="VQ862_001021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001170346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylated-DNA--[protein]-cysteine
                     S-methyltransferase"
                     /protein_id="HET3115383.1"
                     /translation="MQKKYVKILYSSPIGILSLVADDHYLYGIWVQEQKHFERGLGDE
                     TIEEVVSHPILDPVIACLDDYFKGKPQDLSNLLLAPIGTNFEKRVWDYLQGIPYGQTV
                     TYGQIAQDLQVASAQAIGGAVGRNPWSILVPCHRVLGAGKRLTGYAAGVEKKAWLLEH
                     EGVDFKDINK"
     gene            complement(15679..16173)
                     /locus_tag="VQ862_001022"
     CDS             complement(15679..16173)
                     /locus_tag="VQ862_001022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET3115384.1"
                     /translation="MEIRLAFPNEVDAIMQVIEDAKKCLADAGSNQWQNGYPNADVII
                     DDIISGQAYVALEEGELLAYAAVTKSPEEAYEAIYEGNWQAGESEYLVFHRIAVAADV
                     QGKGVAQTFLEGLIEGFDYLDFRSDTHAENKVMQHIFEKLGFKQVGKVPVDGERLAYQ
                     KLKK"
     gene            16308..16754
                     /locus_tag="VQ862_001023"
     CDS             16308..16754
                     /locus_tag="VQ862_001023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000858725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1836 domain-containing protein"
                     /protein_id="HET3115385.1"
                     /translation="MKTTFSYPKWAEIPNINLYLDQVLLYVNQVCAPISPNKDKGLTA
                     SMVNNYVKNGYLTKPDKKKYQRQQIARLIAITTLKSVFSIQEIAQTLNTLQTQASSDQ
                     LYDAFVDYMNQGIDPANPIIQTSCQTVKLYHQTLDLIDHTQEEVIQ"
     gene            16751..17398
                     /locus_tag="VQ862_001024"
     CDS             16751..17398
                     /locus_tag="VQ862_001024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001097995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin III family protein"
                     /protein_id="HET3115386.1"
                     /translation="MNTSLKLSKQLSFGEEIANSVTHAVGAVIMLILLPISSIYSYEA
                     HGFLSSIGVSIFVISLFLMFLSSTIYHSMAYGSTHKYVLRIIDHSMIYVAIAGSYTPV
                     VLTLMNNWFGYLIIVIQWGTTIFGILYKIFAKKVNEKFSLALYLIMGWLVLAIIPAII
                     SQTTPVFWSLMVTGGLCYTVGAGFYAKKKPYFHMIWHLFILAASALQYIAIVYYM"
     gene            complement(17419..18000)
                     /gene="pdxT"
                     /locus_tag="VQ862_001025"
     CDS             complement(17419..18000)
                     /gene="pdxT"
                     /locus_tag="VQ862_001025"
                     /EC_number="3.5.1.2"
                     /EC_number="4.3.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000689933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal 5'-phosphate synthase glutaminase
                     subunit PdxT"
                     /protein_id="HET3115387.1"
                     /translation="MKIGILALQGAFAEHAKVLDQLGVESVELRNLDDFQQDQSDLSG
                     LILPGGESTTMGKLLRDQNMLLPIREAILSGLPVFGTCAGLILLAKEITSQKESHLGT
                     MDMVVERNAYGRQLGSFYTEAECKGVGKIPMTFIRGPIISSVGEGVEILATVNNQIVA
                     AQEKNMLVSSFHPELTDDVRLHQYFINMCKEKS"
     gene            complement(18001..18876)
                     /gene="pdxS"
                     /locus_tag="VQ862_001026"
     CDS             complement(18001..18876)
                     /gene="pdxS"
                     /locus_tag="VQ862_001026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012054698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal 5'-phosphate synthase lyase subunit
                     PdxS"
                     /protein_id="HET3115388.1"
                     /translation="MTENRYELNKNLAQMLKGGVIMDVQNPEQARIAEAAGAAAVMAL
                     ERIPADIRAAGGVSRMSDPKMIKEIQEAVSIPVMAKVRIGHFVEAQILEAIEIDYIDE
                     SEVLSPADDRFHVDKKEFQVPFVCGAKDLGEALRRIAEGASMIRTKGEPGTGDIVQAV
                     RHMRMMNQEIRRIQNLREDELYVAAKDLQVPVELVQYVHEHGKLPVVNFAAGGVATPA
                     DAALMMQLGAEGVFVGSGIFKSGDPVKRASAIVKAVTNFRNPQILAQISEDLGEAMVG
                     INENEIQILMAERGK"
     gene            complement(19028..20407)
                     /locus_tag="VQ862_001027"
     CDS             complement(19028..20407)
                     /locus_tag="VQ862_001027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HET3115389.1"
                     /translation="MSKIVVVGANHAGTACINTMLDNFGNENEIVVFDQNSNISFLGC
                     GMALWIGEQIDGAEGLFYSDKEKLEAKGAKVYMNSPVLSIDYDNKVVTAEVEGKEHKE
                     SYEKLIFATGSTPILPPIEGVEIVKGNREFKATLENVQFVKLYQNAEEVINKLSDKSQ
                     HLDRIAVVGGGYIGVELAEAFERLGKEVVLVDIVDTVLNGYYDKDFTQMMAKNLEDHN
                     IRLALGQTVKAIEGDGKVERLITDKESFDVDMVILAVGFRPNTALADGKIELFRNGAF
                     LVDKKQETSIPGVYAVGDCATVYDNARKDTSYIALASNAVRTGIVGAYNACGHELEGI
                     GVQGSNGISIYGLHMVSTGLTLEKAKAAGYNATETGFNDLQKPEFMKHDNHEVAIKIV
                     FDKDSREILGAQMVSHDIAISMGIHMFSLAIQEHVTIDKLALTDLFFLPHFNKPYNYI
                     TMAALTAEK"
     gene            20701..21624
                     /locus_tag="VQ862_001028"
     CDS             20701..21624
                     /locus_tag="VQ862_001028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000175414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD:protein FMN transferase"
                     /protein_id="HET3115390.1"
                     /translation="MTLRSHSERLMGTTITISLVDEQADIFLQKSFDLLKELEYRFNA
                     NSQESELMEINYQAGIAPVTVHPDLFELISLGLEHSLALSSHLNISIGPLIQTWRIGF
                     SDAKVAQPQEIESVLPLINPHGIELDSSTSTVFLKQKGMKIDLGCLAKGYSADKVAQF
                     LRKEGVTSALINLGGNILTIGKNQARGDNPWQIGIQDPANPRGNHLMTIPVVNKSVVT
                     SGIYERHLTVDGQDYHHIFDSQTGYPVETELASLTIISDKSVDGEIWTTRLFGERPAS
                     ILWQVESLEGIEVILIDKEGHLSCSSGIPTL"
     gene            21684..22289
                     /locus_tag="VQ862_001029"
     CDS             21684..22289
                     /locus_tag="VQ862_001029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HET3115391.1"
                     /translation="MLKLIAIVGTNSKRSTNRQLLQYMQKHFSDKAEIELVEIKAIPV
                     FNKPADKQVPAEILEIAAKIEEADGVIIGTPEYDHSIPAVLMSALAWLSYGIYPLLNK
                     PIMITGASYGTLGSSRAQLQLRQILNAPEIKANVLPDEFLLSHSLQAFNPSGDLVDLD
                     VIKKLDAIFDDFRIFVKITEKLRNAQELLRKDAEDFDWENL"
     gene            22308..23552
                     /locus_tag="VQ862_001030"
     CDS             22308..23552
                     /locus_tag="VQ862_001030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000673688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HET3115392.1"
                     /translation="MKFVGLVGSNYDQSYNRKLLEFIRRYFKLKFELEVLEIDEVPMF
                     NQDEKWDESFQLRYLYNKITRADGVIIATPEHNHTISASLKSVLEWLSYEVHPFENKP
                     VMIVGASYYDQGTSRAQVHLRKILDAPGVNAYTLPGNEFLLGKAKEAFDNNGNITNEG
                     TVKFLETCLDNFVKYVGVVSKLKKPKPIESEDLDCGKPIATTITEVDPDDPEWVEKVA
                     AITGAVSGDTYVKLDHGILTVNQIDMFLKAMPFELTYADDNNQFLYYNNAHQDPDTMF
                     AKRVPPQSGSRMSTVHGSLPPARMKNVEWVIGTLRNGNQEYVRTIVPGSPAGVINTHN
                     YQAMYYPDGSYAGINEIVFNFQPWLDWYLKETGQRLVGGSGPFAPAAGGHGDADATSG
                     ASDSGDAGGHGGDADATAGASY"
     gene            complement(23775..24032)
                     /locus_tag="VQ862_001031"
     CDS             complement(23775..24032)
                     /locus_tag="VQ862_001031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF896 family protein"
                     /protein_id="HET3115393.1"
                     /translation="MDPKKIARINELAKKKKTEGLTSEEKVEQAKLREEYIEGYRRAV
                     RHHIEGIKIVDEEGNDVTPEKLRQVQREKGLHGRSLDDPNS"
     gene            complement(24074..26110)
                     /locus_tag="VQ862_001032"
     CDS             complement(24074..26110)
                     /locus_tag="VQ862_001032"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit beta"
                     /protein_id="HET3115394.1"
                     /translation="MTKNLLVELGLEELPAYVVTPSEKQLGEKMAAFLKENRLSFEAI
                     QTFSTPRRLAVRVTGLSDKQSDLTEDFKGPAKKIALDSDGNFTKAAQGFVRGKGLTVE
                     DIEFREIKGEEYVYVTKEEVGQAVEAIVPGVVDVLKSLTFPVSMHWAGNSFEYIRPVH
                     TLTVLLDEQEFDLDFLDIKGSRVSRGHCFLGKETKIQSALSYEEDLRKQFVIADPCER
                     EQMIVDQIKEIEAKHGVRIEIDADLLNEVLNLVEYPTAFMGSFDAKYLEVPEEVLVTS
                     MKEHQRYFVVRDQDGKLLPNFISVRNGNAERLKNVIKGNEKVLVARLEDGEFFWREDQ
                     KLVISDLVEKLNNVTFHEKIGSLREHMIRTGQITVLLAEKAGLSVDETVDLARAAAIY
                     KFDLLTGMVGEFDELQGIMGEKYTLLAGETPAVAAAIREHYMPTSAEGELPESKVGAV
                     LAIADKLDTILSFFSVGLIPSGSNDPYALRRATQGVVRILDAFGWHIAMDELIDSLYA
                     LKFDSLTYENKAEVMDFIKARVDKMMGSTPKDIKEAVLAGSNFVVADMLEAASALVEV
                     SKEEYFKPSVESLSRAFNLAEKAEGVATVDSALFENDQEKALAEAVETLVLSGPASQQ
                     LKQLFALSPVIDAFFENTMVMAEDQAVRQNRLAILSQLTKKAAKFACFNQINTK"
     gene            complement(26370..27287)
                     /gene="glyQ"
                     /locus_tag="VQ862_001033"
     CDS             complement(26370..27287)
                     /gene="glyQ"
                     /locus_tag="VQ862_001033"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018163989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit alpha"
                     /protein_id="HET3115395.1"
                     /translation="MSKKLTFQEIILTLQQFWNDQGCMLMQAYDNEKGAGTMSPYTFL
                     RAIGPEPWNAAYVEPSRRPADGRYGENPNRLYQHHQFQVVMKPSPSNIQELYLESLEK
                     LGINPLEHDIRFVEDNWENPSTGSAGLGWEVWLDGMEITQFTYFQQVGGLATGPVTAE
                     VTYGLERLASYIQEVDSVYDIEWADGVKYGEIFIQPEYEHSKYSFEISDQEILLENFD
                     KFEKEAGRALEEGLVHPAYDYVLKCSHTFNLLDARGAVSVTERAGYIARIRNLARVVA
                     KTFVAERKRLGYPLLDEETRVKLLAEDAE"
BASE COUNT         8057 a         6130 c         4986 g         8157 t
ORIGIN      
        1 ttggaaagga ccagatgtcc gtcttttaaa atggtcttaa aggtttcttt atacttgagg
       61 ctgtattcaa ttgcccttcc tagttttgaa cctgctaaaa ctgactgacg gcggcaccaa
      121 gcaaagaagt cttccattag gggctggacg tttctgtagt cgttcatcag ctggcaaagc
      181 ctcccagtct ctttccaagg caaataactg gtcacgatag gctaaacctt tagctcctaa
      241 ggatgattta tctgcttgct tgggggtcgc ttcaaaaaat ttccttctca catgcgccca
      301 acatccaaca agttcagctt cttccagttg acgataagct tctagcggtt cgcagtttac
      361 caagcttagc gtcgccttgc tcctaaacct tagactgcta tcgcataggc agaactagag
      421 gactaaagtt ctaagttact gccgcaacat atcacaatgc atatagccag aataatttcc
      481 taggaattct tgcactaccg aaccactccg acgctgatca tggtggtaca gcgtaatccc
      541 ttgtttctca gctttcccag acaaaaaagt ccaatagtaa gtcagctgac tatcactttc
      601 taagacccga taagaggttt catctgcatg aagaagagct tgttctaaca acttttctcg
      661 taaaaggtta taaagggact ctaaatagta ttgactcgcc ttgatatgcc aattagcaat
      721 ttccttacgt gtgattggta aacccatctt agcccaatct tcttcttagc gataattggg
      781 taccttcaga ataaacttct gatggatggt gtgagcgata atagaagctg agccaaggct
      841 atgcgccaaa ggggctttag gaataggagc tttcacgatt ttatcacttg gattattctt
      901 actgcatgtt tggcatttgt aagcgtgttg gatatgattc actcttttta attgcgcaag
      961 aataaagacc aattcttgtc gttgaaggct cgctccaatc tcttttagct ctccctgaca
     1021 gtcagggcaa atgcagttct ctaagcgatg atgaacttct tctgaatcaa attgggcaag
     1081 aatagcttga cgtttccctt tagctttctt acgtttatag gtgatttctt ctctttcaac
     1141 tgggtaagtc agagtcttct tccatatttt gttcctcttc aaaaagactg agttgtccag
     1201 atgggcaaac acttttctca gaggattttc catagagctt ttgcgttaga taagccactt
     1261 gttcacgaag aagggcaagt tcattggtga gactatcaat tgtagcactc tgttgttgaa
     1321 tgattttcaa tcttctccca tagactttcc tccttatttc ctaactttat tatatagtgt
     1381 attgaatcta taacagtaca ccttgactgc taaaatattt ctataaatta atttgacttt
     1441 cctgatagag atgttcatat cttatttcaa ttcactatac taaaaagaaa gtcctcattt
     1501 caatagaaat cacgactttc tgatgaattt atttttggag tgatagaaaa gcccttcata
     1561 agccagtcta cttgttcagg tgtgagagct ttgacatcct tttctgtact gggtcaagtc
     1621 agtctgccgt tctcaaagcg tttatatagt agccaaaatc cttgaccatc ccagtaaagg
     1681 gctttaaagc ggtctttacg tccaccacaa aagagaaaaa cttgaccgga gaaaggatct
     1741 aattcaaagt gggttttaac cagataagcc agtgaatcaa tgccttgcct catatccgtt
     1801 ttcccacata cgagatagac ctgccctagg ctagatagat gaattgtcat agagcaacac
     1861 cttatccaaa agctgttcta ccatttcgag attgagagat tgaaaaaaac ttacttcaag
     1921 cttgccaata cgaattttaa gcagaatatc atttctcttt ttagaatcaa aaggacgaga
     1981 ttgtggaatc tctacaggaa caataggttg tggcattaaa atatcctcca atagttttac
     2041 tttactaata gtatacagga ggagctccat gaatgataga taccttgtta tgacgcgctt
     2101 accatattag aaagttggct ctctaattaa attaattctc attatatata tcaaaagacc
     2161 gcagtttgaa aactacggtc taattttttg tccaaatgta aaccacttgg aactattatt
     2221 caatttattc tttttagcaa atgttcccgt tttaatccca gttacagttt ttaatccttt
     2281 gtaaccgttg attttacaaa gcttttaatt tttttgcgat tactcccact caactgttgc
     2341 aggtggttta cttgtaatat cgtagacgat acggttaaca tgatccactt catttacgat
     2401 acgtactgag attttttgaa gtacttccca tggaattttg gcaaaatcag cagtcatacc
     2461 atcgatagaa gtgatagcac ggattgcaat cgtgtagtca tacgtacgac cgtcacccat
     2521 aacaccgact gaacgaacgc ctgtgttaac agtgaagtat tgccaaatat cgcggtcaag
     2581 tccagcttta gcgatttctt cacgaagaat agcgtctgat tcacgaacgg tttcaagttt
     2641 ctcttcagtg atttcaccca tgacacggat agcaagtcct ggtcctggga atggttggcg
     2701 ccatacgata tggtctggca taccaagctc tgtaccaaga gcacgaactt catccttgta
     2761 aagagtattg agtggttcaa tcaattcaaa ctgcatatct tctggaagac cacccacgtt
     2821 gtggtgtgac ttgatagttt gagctgtatc cgtaccagac tcgataacat ctgtatataa
     2881 agtaccttga gcaaggaatt tcacatcttt gagcttgctt gcttcgtcat cgaatacata
     2941 gacaaactcg ttaccgatga ttttacgttt ttgttcagga tcagaaacgc cagcaagttt
     3001 gtcaaggaaa cgtttagcag cgtctgcttt gacgatattc aaaccaaact taccaccgag
     3061 catgtccata acttgatcag cttcgccttt acgaagaaga ccgtggtcca cgaagataca
     3121 gatcaattga tcgccaatcg ctttttggag aagaacccca acgacagatg agtcaacacc
     3181 acctgataga ccaagaagga cacgtttatc accgacggtt tcacgaattt ttttgatctg
     3241 catgtcaatg aaattatcca ttgaccagtc acctttagcc ttacaaatgt taagggcaaa
     3301 gttacgaagg atatcatttc cgtatacaga atgacgaact tctgggtgga attggatacc
     3361 gtaaatgtgt ttatctgggt tttcgatggc tgcgtatggg cagtcagctg atgtacctgt
     3421 acgaacaaag tcagcaggaa tctcagtaac cgcatcacca tggctcatca aaacagtctg
     3481 ttcatcaggt gttgattcaa aaagcgctga tggtgtgtga gttagggttg attgaccgta
     3541 ttcacgattt ccagcatcac ctgcaggaac aacttttcct ccaagtttat gggtcaataa
     3601 ctgcatacca taacagattc ccaaaattgg aattccgagt tcgaagattt ctgggtcaat
     3661 atcaaatgaa ccatcttcat atacagaatt tggaccacct gatagaataa ttcctacagg
     3721 attgacttca cgaacttcag cagctgaaat tttatggctt tttagttctg aaaaaacacc
     3781 aatatcacgg atacggcgtg aaatcagctg gttgtactgg ctaccatagt ccaatacgat
     3841 gattttttct acatcttgca aatcagttga aatgttgctc atctttttcc tttctcaaaa
     3901 gaaatatctt ttctcaatat tctatcacaa ataagggcga attaccaact aaacaaggcg
     3961 aagtttgact ttttctagtt tattggggta caatagagaa aagatagaaa tgaagtgaaa
     4021 aatatgctac ctgcttatat gaaaatccat gatcagataa aaaaggatat tgacgagcac
     4081 cgttgggcta ttggtgagag gcttcccagt gaaagagatt tagctgagca gtttgcggtc
     4141 agtcgcatga ccctccgcca agccgtatct ctattagtcg aagaaggcgt cttagagcgc
     4201 catgtaggaa gcggcacctt tgtttccagt actcgagtac aagaaaagat gcgagggaca
     4261 accagtttta ctgaaattgt caaatcccaa ggtaaagttc cctctagcca gctcatttcc
     4321 tacaaaaaaa ccattcccaa tgagcaagaa gttgccaagc taggaatttt tccaacggac
     4381 aatattatcc gaatggagcg ggtccgctat gccgaccaag ttcccctagt ttatgaagtt
     4441 gcttctattc ctgaaaaatt cattaaggac tttaaaaaag aagaaatcac cagtcatttc
     4501 ttccaaacct tgcaaaaaca tggctatcgt atcggcaaat ctcaacagac catctatgct
     4561 cgccttgcta aagaaaagat tgcccactat ttggaagttg aaaaaggaca tgctattctt
     4621 ggattgaccc aggtttccta cctagaagat ggtactgctt ttgaatacgt aaaaagtcaa
     4681 tatgtaggcg aacgctttga attttatctt gaaaataatt agattaccac gcaaaaactc
     4741 tctgtcacgg acaaagagtc ttttttattt ttctaagaat aaatctttca aagaaatcaa
     4801 agttacagca aacaatatca ttgccatacc aagaaaatca atgggataaa attgttcatt
     4861 cattattaag aaggcaaaga aaatcgccga tattggctca attgaagcca acaagcttga
     4921 cttgaccggt cctatcagac tggctccttt aaggaaagct gtataggcaa agacagtccc
     4981 gataaggata atgcctgcaa acgcaaggag aaaatcaaga ctagtcggga tatcggcctg
     5041 tagaacccct gtaaaaggaa gagcgaccaa acctgctatg accattccca caccaatgac
     5101 caagctgctc ccccactttt taatcaaggc tatgggtaaa atgatataca gagcataagt
     5161 aaaggcagaa aagagacccc agaacagacc agcaggtgtc atggataact ggtccaactg
     5221 cccatgtgtt gcgatcagga aggttcctcc gatggcgaat atgatggaaa ctatctctcc
     5281 cagtgtcggt gccaccctat ccttgataca gctataaatt aaaattccga caggacaaac
     5341 atactgaagc accgtcgctg ttcccgcatt ggtctcctga atagcagaca gataggcgaa
     5401 ttggttgaga aaaagaccaa tcagagcaaa aataagaaga gacagcaaac tctttctatc
     5461 ctttaaaaag accagtattt tatcctttgc agtagcataa gccaagagca tgagaattcc
     5521 accagcgatt aaaagacgca agttggtcaa gaccagagcc gaaattccgt gtgccattag
     5581 gtattggcca ctcgttcctg acaaccccca agcaatacca gccacaactg ttagtaaagt
     5641 cccttttaaa ctatttgaca tgtctctcct tactcttctt tgcgaatcaa gttcatcact
     5701 tgattgcggt ctaatatcca ttgagctctc tcgtcctttt cataggtacg attcgatagg
     5761 aaaatagtgg cttcttgctt ctgacgattc cacatgataa aggtacctgt atagcccgta
     5821 tggtctagcc aatctccttc caaattccat gctaaagaac gttccttgtc atccaaagga
     5881 gaaaaatttt gacttaagtc tcttgcaaaa tcatctgcta aatagtgttc taaaaagatt
     5941 tgtaaatcct ttatagtcga aaataaacca gcactcccag catgtctacc caggagacga
     6001 gccttgggat catgcactat gcctgcctct acacctctaa ctgttggaac agcaagctca
     6061 actgacccaa acttggtttc cgtcattccc caaggtttcc agacttgatc ctttaaaatc
     6121 acatccaaat cttgattaaa aattctttcc aaaataaagc ccaacagcaa aaaatggaca
     6181 tccgaataaa gaaaggctgg ctgacttcgt ctgttgagat gaaacatcgc ttcctttaat
     6241 tcaggggctg ttaaaagatc acgattagga ataaaaggat caaggtctgt tgcatgagtc
     6301 aagagctggc gaatagtgat gtctggataa tcactctcag gtaaaaaatc tattaccagt
     6361 ctatcaatat ctaattgacc tatttcccac aagaaggtac aaactgtgcc aaccccaaca
     6421 accttgctga cactagctag gtcataaact agtcctgcct cagtctgcaa gccatgctct
     6481 gggtcactct ggcctaaata gaactctgtc cattgattgt ccttaaaata cgcaaaagag
     6541 gctccgggat aaattcctgc ctcgatttgt tcttctattt ttttaataat cttggtccac
     6601 ttcatacttc ttcaaaccac aattcaacat tatttctatc tttacaaagg aagaattttt
     6661 cagacttagg aataaaatat tcagtagact caaacttctg gcgaagactt gctatgtcta
     6721 attcattgac caagaacttg agcatagata agtcccaggt aaccgtattg tccacagtca
     6781 aatcctgccc ctgagctgga ataaaatcaa gggatgcccc aatttcagat gattccaaga
     6841 aactttcgat atcagttggg agatgtaatt ccatagaaat ctcaaattta cttaaagaaa
     6901 ttgataccaa atctgtttga aattcaggct tttctcctac ttctactaga cttgctctgt
     6961 catcttccgc atgaatcaaa atcaaatcat cttctggtga gaaaatttca aaagcgtagc
     7021 cattttgacc tttatataat cgatgaatcg aatctgtttt agataagatt ccttcaattt
     7081 ctaagggatt ttccaccttg acaatcaatc tagctagttt ttttcttccc tctaccttac
     7141 gagtacgcat actgggagct tcttctaaaa ccagcttttc aagacccgtt tggtcaccta
     7201 gtgacagaaa ggccgattct tctaacaagg ccttcattcc aagggtttca atataaaatg
     7261 tttcatttaa ttttctatta ttagctttta aagtaggaat aatccgtaca atctgattta
     7321 cattcataaa ttcctccgtc actttttatt ttaaaggatt ttagaatttt ttacaagata
     7381 ttatgctcaa atttaacatt atttagctat ttagtaaaga tagtctttca aggcttttga
     7441 caaagcctga taaccagcaa tactgaggtg cagtccatca gttgtatatt cttttttgag
     7501 ttggcctgct tggtctgtca aacaatcaaa tactggcaca aattccacct gcatataggc
     7561 agatgcaagc tcttgatagg cttgattcca gttctgaatt ttttcattcg agcggatata
     7621 gactgcctgc tggtactcct ctccctcatt gacaggcaaa atggaaagca atttaatctc
     7681 tgtcaatgga taatcgcgag caacggattg aatgatagct tcgagattat tgagagcctc
     7741 attcacagga acatcctttc cgatatcatt tgtcccaatc agaagaaaaa ttttatctac
     7801 tgctccacca tatagatgag catcaaggtt ctctagtaac agtcctgtct gatagccacg
     7861 aattcctcga ttgacaatcg tctttgaagt cccaaatagc tcctgtagag gataatactc
     7921 gacaatggaa tccccaataa aaagaatgtt tggttctaca acagaaatgt gatttaggtg
     7981 acgatactta gtttgaattt tttcttgttc ctttaggagc caattttcta ataactgtac
     8041 tgccacttca ttctcctttt tctaaccagt tttccaagac ttgataaact cctccttggc
     8101 tgttggctgg tgctagagca gtcgccacag ctttggcttt ctcatcagca ttttccatcg
     8161 cataggcaat tccagccatt tcaagcattt caacatcatt ttcactatca ccaaaagcca
     8221 tgatttcttg ggatttcaag tcccagcgct tgagtaattc ctccaagccc catgctttat
     8281 gaatcccagc ttggaggata tcaatgcaac catagccact ggatacagct cggacacggc
     8341 catcaaagag agcattgatt tcttccaaaa ccgaactcaa acgttcctca ccaacaacca
     8401 tgctcatctt gagcacacca ccaaagaggt cagatgttaa ttcatccaca aattgcatcc
     8461 gttggtagaa tttttcaatc atttctggag tcataaaact ttcaagatct gtaaaaatcg
     8521 taccttcctt gacaaaatca cccttcatcc ccgttacaac aaactggtcc tgacacgctc
     8581 gacccttgaa atgagtcaaa gccttgttga caatggcgtc atcccatgtc tgagcctgaa
     8641 tcaattcatt gttttcaaaa atacgagcgc cattagcaac aaccagaacc actcgatcca
     8701 ccaagggact cagtagttgt ctcatgcggt gaatttcatt gcccgtcgca atgacaaaac
     8761 gaatgcccct ttgatccaac tgatctaaaa tcttttccaa tcgtgggaga tcaagctgac
     8821 ctctagcatc cagcaaggtc ccatccatat ctgtcgcaat taccttaatc atcatttact
     8881 ttcctctgga ttcaagctaa taccacttca atcccacatg ttcattcatt tctttatagg
     8941 ctgtatcaat tcgttcctta gtcgcttcat ctaactggtc acgatgactg ccatcctcta
     9001 taaaatcttc caaaatataa gtttggtaat gatacaaggg atatccttct ggtgaaaagg
     9061 ttccctttgg tgttcgattg acccaagtag gatgagcttt agctgttccg atagttgttt
     9121 ttccatcctt cttcttgatg gtgacatcca tgagaacacc acgttcagtc cacttagcat
     9181 tctcttcatc tcccatagat tcaatccgtt gattggaaat gaagttcccc atttaataga
     9241 caatgagctt cttatctcca tctttttcca ccgtttcaga tggttcaaca acgtgaggat
     9301 gccctccaaa gataatatcc gctccccaat cgatcatctt gtgataaaga gctttttgtt
     9361 cttcagttgg ttccaatcga tactcaacac ccatctgaag catgataatg gtgatatctg
     9421 cttccttctc tgcccgttca atttcaacct tcatcttatc ttcgtttaaa tctgaaagat
     9481 aacgattata gtcttcctga gaaatatact gctcaattcc attgaaacca taggaatagg
     9541 ctaacaatgc aaccttgata ccattcactt ccttaatgac cagcggagcc tgaacacgtg
     9601 gttcgtgcgt ataaactccg attggagtga ttccagcttt ctcaataata tcggccgttg
     9661 aaataactcc ctcaagttga aataactccc tcaagttgcg aatccaaaat atgattatga
     9721 gctaaatcca gcacatgata acctgcctcc ttaatagcat ccataacttc agcaggagca
     9781 ttaaagagaa gataacccgc taaataatga tccttattaa tggttccttc aaaatcacca
     9841 atagctaaat ctgcttgctt gagccaagga gtcacatact caaaattttc atgaaagtca
     9901 taggtaccgt cttctttttt agctgaaaag aaaagtccat cgtggtagag caaatccccg
     9961 tgggccataa ttctggcagt tttttcctct tcctactcct gagacttttg cttagtcccc
    10021 tcttgagaaa tagtatctcg tttttgacta gtcaagggat tccttggaag ctttcaaaca
    10081 acaagaccaa gcccttcata aaacgaaaag ctaaaccacc ctgatttcga ttttatcttc
    10141 tttgtatctt cattctccct actttcttat gcaagccttt tctttttatt atatcacaga
    10201 taagtatttc tttcacaatt gaattgaact tcccatctat tttctataaa tcctaaatgc
    10261 cataatgctt tcaattcttg tcattttgtg atatcatgta gaggaaatga actaatccac
    10321 agtggcttat ttcaagtata ccacttgggc tttggcagta gctaactgca ctaaatataa
    10381 tataaggaga gaaaatgtct gcaatagaac gtattacaaa agctgctcac ttaattgata
    10441 tgaacgatat tatccgtgaa gggaatccta ctctacgcgc gattgctgag gaagtcactt
    10501 tccccctatc tgaccaggaa atcatcctag gcgaaaagat gatgcaattc cttaaacatt
    10561 cccaagaccc tgtcatggct gaaaaaatgg gactccgcgg tggtgttgga ctggctgctc
    10621 cccagttaga tatctcaaaa cgcattatcg ctgttttggt acctaatatt gttgaagaag
    10681 gcgaaactcc acaggaagcc tacgatttgg aagccattat gtacaatcca aaaatcgtct
    10741 ctcactctgt tcaagatgct gctcttggcg aaggagaagg ttgcctgtct gttgaccgta
    10801 acgtgcctgg ctatgttgtt cgccatgccc gcgttactgt tgactacttt gacaaagatg
    10861 gagaaaaaca ccgtatcaaa ctcaaaggct acaactccat tgttgttcag catgaaattg
    10921 accacattaa cggtatcatg ttttacgatc gcatcaatga aaaagaccca tttgcagtta
    10981 aagatggttt actgattctt gaataaagaa aatcccgttg caagacgggg ttttgtgtta
    11041 taatagaggc atgaaaacaa atgatattgt ctatggcgtc cacgccgtta ccgaagccct
    11101 ccttgcaaat acaggaaaca aactctacct ccaagaagat ctccgaggta agaatgttga
    11161 gaaagtcaag gaactagcta cagaaaagaa ggtgtccatt tcttggacat caaaaaaatc
    11221 tctctctgag attactgaag gtgctgttca tcaaggtttt gttctacgag tgtctgaatt
    11281 tgcctatagc gagctagatt acatccttgc aaaaacacgc caagaagaaa atccacttct
    11341 attgattcta gatggtctaa ccgatcccca taatctgggt tctatcttgc gaacagccga
    11401 tgcgaccaat gtttcaggtg tcatcattcc caagcaccgt gctgtcggag taactcctgt
    11461 cgttgccaaa acagccacag gtgctattga acacgttcca attgcccgag tgacaaacct
    11521 cagtcaaacc ttagataaac tcaaggatga aggcttctgg acctttggaa cggatatgaa
    11581 cggtactcct tgccacaagt ggaatacaaa agggaaaatc gccctcatca tcggaaatga
    11641 aggaaaaggc atctctagca acatcaaaaa acaggtcgat gaaatgatta ccattccgat
    11701 gaatggacat gttcaaagcc tcaatgccag tgttgctgcg gccattctca tgtacgaagt
    11761 ttttctaaat agactataaa aaagtttcca gtcatctgat tggaaacttt tttataatta
    11821 actatgttct gtgataaact tgtaggcttc ttgaccagcg atagctccat ctccaactgc
    11881 tgttgttact tggcgaaggt ctttcaagcg aacatctcca actgcaaaga taccgtcgac
    11941 tgcagtcttc atgtggctat ctgtcacaat ccagcctgcc tgatcttgga tattcaattc
    12001 tttaacaaaa tcgctaagag ggtccaaacc aacatagata aagacaccac cgaaggcttg
    12061 ctctgtcact tgacctgttt tcacattttc aaaaacgaca gattctactc tgttttcacc
    12121 cttgatttcc ttcactacag aatcccagat aaagctgatt ttttcattcg caaaggcgcg
    12181 atcttgtaaa accttttggg cacgaagttg gtcacgacgg tgaacaatgg taacagtctt
    12241 agcaaaacga gtcaagaaga gggcttcttc aacagctgaa tctccaccac caactaccaa
    12301 taaatcttgg tcacggaaga aagcaccatc acacacagca cagtaagaaa caccacgact
    12361 gttcagttct tcttctccag gcactcccaa aggacggtgt ttagaaccag ttgctacgat
    12421 aactgtacgt gtttcatatg tttggtcatc agtcatcact ttcttaaaat caccatggtc
    12481 ttcgacattt tcaacataac cataaatgtg ctcaacacca agattttcaa gtggttcaaa
    12541 catcttttca gccaattcag gtccactaat attagcgtat cctgggtaat tttcgatatc
    12601 agatgtatta ttcatctgac cacctggcag accaccttca atcaaagcta cttttagatt
    12661 gcttcgagca gcatacaagg ccgcagtcat ccctgcaggt ccagcaccga taataatagt
    12721 atcgtacata tagattcctt ctttcttgtt gtaactatct ttattctaac tctttcttgt
    12781 caatcacgca aggattatgc cttgaaaaca agaattaaac tcataaccgc aaaggataat
    12841 actgggacaa ccaagactcc aatcataatc atatcataga gatgggcttg gcgagccctg
    12901 gctgtcttat caactcccga catggctctc agaccaatcc aaatccctaa aaaaatcaga
    12961 acaaggatgg tggtcaagat caaactctcg aaatataaag aaaatagttg cagtagcatg
    13021 atttctctca tttctatctt ttttaaagag taaactcagc tagtccaact aactgagttt
    13081 tcctttatct attatatcaa atataagtcc gtttgtaact agcgaagaat tcttttgtcc
    13141 gctcttcttt aggggtgtgg ataatctcat ccggagttcc agactcgatg attttcccct
    13201 tatctaagaa gagaatttta tccgcaactt gggctacaaa ggacatgtca tgactgacca
    13261 aaatcatggt ctgacctgac ttagcagcat ctgcaataga cttttctact tcaccgacca
    13321 attctgggtc aagggctgaa gttggttcgt ctaagagcaa aacatctggt ttcatagcaa
    13381 gcgcacgcgc tagggcaacc cgttgcttct gtccacctga taaatggcga ggataatggt
    13441 tttcacggtc cgaaagccca accttagcca actcttcctt ggcaatctta gtcgcttctt
    13501 ggtcagataa tttcttgaca acaaccaagc cttctttcac attatcaagt gctgttcgac
    13561 gttcaaataa attaaactgt tggaaaacca tagacaactt acggcgtagg gcaaggattt
    13621 cttcttgagt gattttagaa aaatcaactg aaaaaccatc aatctgaata gagccactgt
    13681 caggtgtttc aagataattg agactgcgaa gaaaggttga ttttccagct cctgaagaac
    13741 caatcaaggc tacaacttcc cctttttgaa tatccaagtt cagatgatcc aagacagtct
    13801 gtcctgaaaa ggatttgctt aaattcgaaa tcttaatcat taacgaaggt ctcctttcac
    13861 atctgtttgc actgtatcag gtgcagaaat agccattttt ctctcgatga aacgaccgag
    13921 gctttcaatt ccgatattga ctacccaata aacaagggca acagagatga agcgttcaaa
    13981 atagcgataa tcagctccac ctagaatctg agcttgggca aagacttcca caacacccgc
    14041 actaaaagct agagatgttc ccttggtcaa accgatgagg gaattaatca aggttggagt
    14101 agctaccacc gctgcattag gaataatcac tcgtcgataa acttgcgctc gggtcatacc
    14161 cagactgcgc gccgcctcaa tctcaccagg attaactgag agaatggctg cacgaatggt
    14221 ttcactagca taagctgcct cattaaaggc aaaagcgaca atcgcaaaag ctgcagctgg
    14281 aatcgcattg atattgagac cagttcccca ttgctgattg agggctttca aagccaaagg
    14341 aattccgtag taggtcaaca tgagttgcac caaaatcggt gtccctttta agaaactaac
    14401 aaagaaggcc tgcaagggat ataaaatctt gacacgattg atcttcacaa tggcaaaaag
    14461 aagcgccaaa accaagccaa aaagggcacc accaattgtc aacataattg ttgttggaag
    14521 ttgttggaca attctaggga ttccatcaaa gaccgaacgt aggctaaaca gcttgccatc
    14581 cggaatcaat tgcatcaagt tttggtacca atctgatgct aaaatcgttg taacattcat
    14641 aaaaacatcc tcttctgata atgattcatt ctaccatgct tctgccgtca atgaaattat
    14701 ttgctacggt cagatacaga ctttgtctac ctactagttt atcatacttt gaaacaggga
    14761 agttatatat tttatctatc aaagagatag ataaaaacta tttcagtccc agttcttcat
    14821 aagattttcg ataaccgatt tgcttaacag ttccattttc tactaaaatg ggccgtttta
    14881 acaacatacc gtcacttgct agcaactcag ccgcttcttg gtttgacaaa cttcctacct
    14941 tatcttttag ccctaattca cggtatttga taccactggt gttgaaaaat tgcttcaatt
    15001 caaatcctga ggtttctagc caattcaaaa tgacttcttg gctaggtgtt tcttccacga
    15061 tatggacggc tttatagtcc acacctaatt gatttaattc ttgttttgct tttttacaag
    15121 ttgaacattt ggggtattcg ataaattcta acatgtgctt ctccttctat ttgtttatat
    15181 ctttaaaatc tacgccttca tgctccaaga gccaagcttt cttttccact cctgcagcat
    15241 agcctgtcag acgcttgcct gctcccaaca cacgatgaca aggtactagg atagaccaag
    15301 gattgcgtcc cactgctcca ccaattgctt gagcagaagc cacttgcagg tcttgagcaa
    15361 tttgtccata ggtcactgtc tgaccataag gaatgccctg taaatagtcc caaactctct
    15421 tttcaaaatt cgttccgatt ggcgccaaga gcaagttgga taaatcctga ggcttgcctt
    15481 taaagtaatc atctaagcaa gcaataactg ggtctaaaat aggatgacta acaacttctt
    15541 ctatcgtttc atctcctagt cccctctcaa aatgcttctg ctcctgaacc caaattccat
    15601 acaaataatg gtcatcagct acaagtgata gaataccaat tggtgaggag tagaggattt
    15661 ttacatactt cttttgcatt atttctttaa tttttgatag gccaagcgtt cgccatctac
    15721 tggcacctta ccaacttgtt taaaaccaag tttttcaaaa atatgttgca taaccttgtt
    15781 ttcagcatgc gtatctgagc gaaaatcaag ataatcaaaa ccttcaatca agccctctaa
    15841 gaaggtttga gcaactcctt ttccctgcac atctgctgcc acagcaatac ggtgaaagac
    15901 tagatactct gactctccag cttgccagtt tccctcataa atagcttcat aggcctcctc
    15961 tggactcttg gtcacagcag cataggctag cagttctccc tcttccaagg ctacgtaggc
    16021 ttgccctgag atgatatcat cgataataac atctgcattt ggatagccat tttgccactg
    16081 gttactacca gcatctgcta aacatttttt ggcatcctct atcacctgca tgatggcatc
    16141 tacttcattt ggaaaagcta aacgaatttc catctttttt cctcatttct gactagtttc
    16201 tcccatcata gcataattta agtctttcta caagcagtta aaacttgact ttgtattttt
    16261 gttattttat aatctagtta tcaaaactat ataaaaagga gttgaaaatg aaaactacct
    16321 tttcctaccc aaaatgggca gaaattccaa acattaacct ctatctggac caggttttgc
    16381 tctatgtcaa tcaggtctgc gcccctatct ctcctaataa agacaaaggc ctaacagcat
    16441 ctatggtcaa caattatgtg aaaaatggtt acctgacaaa gcctgacaaa aaaaaatacc
    16501 aacgccaaca gattgcccgt ttgattgcta tcacaaccct caagtctgta ttttctattc
    16561 aagaaatagc ccagacactt aatactctac aaactcaagc aagttcagac caactctacg
    16621 atgcttttgt ggactacatg aaccaaggaa ttgacccagc taaccctatt atccaaacca
    16681 gctgccaaac cgttaaactc tatcatcaaa ctctagactt aatcgatcat actcaagagg
    16741 aggtaatcca atgaacacta gtcttaaact cagcaaacaa ctcagttttg gagaggagat
    16801 tgctaatagc gtgacccatg ctgtgggtgc agtcatcatg cttatcttgc tgcctatttc
    16861 atccatctat agttatgaag cacacggatt tttatcctct atcggcgttt ccattttcgt
    16921 catcagtctc tttctcatgt tcctatcatc caccatttat cactctatgg cctatggttc
    16981 gacccacaaa tatgttttgc gaatcattga ccattctatg atttacgttg ccattgccgg
    17041 ctcatacacg cccgttgtct tgaccttgat gaataactgg tttggctatc tgattattgt
    17101 catccaatgg ggaacgacca tctttggtat tctctataaa atctttgcta aaaaggtcaa
    17161 tgagaaattt agccttgctc tttacctgat tatgggctgg ttggttctgg ctatcattcc
    17221 tgccattatc agtcaaacga cacccgtttt ctggagtctc atggtaactg gcgggctctg
    17281 ttatacagtt ggagctggat tttatgccaa gaaaaaacct tatttccaca tgatttggca
    17341 tctctttatc ctagctgcgt ccgcacttca atacatcgct attgtttatt acatgtaaaa
    17401 aagttgagaa attcaatctc aacttttttc tttacacata ttgataaagt actggtgcaa
    17461 gcgcacatca tcagtcaatt ctggatgaaa agaacttacc aacatatttt tttcttgggc
    17521 tgcaacaatt tgattgttca ctgttgctaa aatttctaca ccctcaccaa cactactgat
    17581 aatcggacca cggataaagg tcattggaat cttgccaact cccttacatt ctgcttccgt
    17641 gtagaaactt cctaattggc gcccataagc attacgctcg accaccatat ccatagttcc
    17701 tagatgactc tctttctgag aagtgatttc cttagccagc aaaattaagc ccgcacaggt
    17761 cccaaacact ggtaagccag atagaatggc ttctcggatg ggaagtagca tgttctggtc
    17821 acgtaagagc ttgcccatgg ttgtagactc accaccaggc aaaatcaaac ccgacaagtc
    17881 actctgatct tgctgaaaat catctagatt tctgagttct acactctcga cacctaattg
    17941 atctagcact tttgcatgtt ctgcaaaggc cccttgcaag gccaatattc cgattttcat
    18001 ctattttcct cgttcagcca tgagaatttg gatttcattt tcattaatac caaccatggc
    18061 ttctcctaaa tcttcagaga tttgagctag gatttgagga ttacggaagt tagtcacagc
    18121 cttaacaatg gcactcgctc gtttaacagg atctcctgac ttgaaaatac ctgaaccgac
    18181 aaagaccccc tctgccccta attgcatcat taacgcagca tctgctggcg ttgcaacacc
    18241 tccagcagcg aaatttacaa ctggcaattt tccatgttca tgaacatatt ggaccaattc
    18301 tacagggact tgcaaatcct tggcagcaac ataaagctcg tcctcacgta agttttgaat
    18361 gcggcgaatt tcctgattca tcatacgcat atgacgaaca gcttggacta tatcccctgt
    18421 ccctggttct cctttggtac gaatcatgga agcaccttca gcgatacgac gcaaggcttc
    18481 acccaaatcc ttagcaccac agacaaaagg aacttggaat tctttcttgt ccacatggaa
    18541 acggtcatca gctggagata gaacttcact ctcgtcgata taatcaattt caatagcctc
    18601 taaaatctga gcttcaacaa aatgcccgat tctgacctta gccattactg gaatactaac
    18661 cgcttcttgg atttccttaa tcatctttgg gtcgctcatg cgggaaactc ctccagctgc
    18721 acgaatatca gccggaattc gttccaaggc catcacagct gccgcaccag cagcttctgc
    18781 gatacgagcc tgttcaggat tctgcacatc cataataaca ccacccttga gcatctgtgc
    18841 caagttttta tttagttcat aacgattttc agtcatttgt tttatcctca tcatttgtat
    18901 tggtagctac cttttcattt taagtcagaa cagaatgaag cacaagataa aaaaactata
    18961 attgtatggg gacagattag ctaaaaacta tctgacctta acttaaggcc agatagctca
    19021 ttcattttta tttttcagcc gtaagggcag ccattgtgat gtagttgtat ggtttgttga
    19081 agtgtggcaa gaagaagagg tctgtcaatg ccaatttatc aattgtcaca tgctcttgga
    19141 tagcaagtga gaacatgtgg attcccatgc taattgcaat atcatgtgaa accatttggg
    19201 caccaagaat ttcacggcta tctttgtcaa agacaatctt aattgctact tcatggttgt
    19261 catgtttcat gaattctggt ttttgaagat cgttaaagcc tgtttcagtt gcgttgtaac
    19321 cagcagcttt cgctttttca agagtcaaac cagttgaaac catgtgaaga ccgtagattg
    19381 agataccatt tgaaccttga acaccgattc cttccaattc atgtccacaa gcattgtagg
    19441 caccaacgat accagtgcga acagcatttg aagcaagagc gatatagctt gtatctttac
    19501 gagcattgtc ataaacagtc gcacagtcac caacagcgta aacgcctggg atagatgttt
    19561 cttgtttctt gtctacaagg aaggcaccgt tgcggaagag ttcgatctta ccatctgcaa
    19621 gggctgtgtt tggacggaaa ccaactgcaa ggataaccat atccacgtca aagctttctt
    19681 tgtcagtaat caagcgttca actttaccgt caccttcgat tgctttaaca gtttgaccta
    19741 gagccaagcg gatgttgtga tcttccaagt tcttcgccat catttgtgtg aagtctttgt
    19801 catagtaacc gttcaagaca gtatcaacga tatcaacaag gacaacttct tttccaagac
    19861 gttcaaaggc ttcagcaagt tcaacaccga tgtaaccacc accaacaacg gcgatacggt
    19921 cgaggtgttg gctcttgtca gaaagtttat tgataacttc ttcagcattt tggtacaatt
    19981 tcacgaattg tacgttttca agagttgctt taaattcgcg gtttccttta acaatttcaa
    20041 caccttcgat tggtggcaag attggtgtag aacctgtagc gaaaatcaat ttttcgtatg
    20101 attctttgtg ctcttttcct tcaacttccg ctgtaactac tttgttatca tagtcgattg
    20161 aaagaacagg tgagttcatg taaactttag cacctttagc ttccaatttt tctttatcag
    20221 aatagaacaa gccttcagca ccgtcaattt gttcaccaat ccaaagagcc attccacatc
    20281 ctaggaaaga gatgttagag ttttggtcaa atacaacaat ttcgttctca tttccaaaat
    20341 tatccaacat ggtattgata catgctgtac cagcgtggtt agcaccgact acaacgattt
    20401 tactcataaa aatttcctgc cttcattcta aatttacctt actagtatac catttaccgt
    20461 tagcgtttac aaggggggta ctattatttc agcatttttt atcaaaaata attccccatt
    20521 tatcctgttt tcaagcctca tgaattttat gagcatattt cttgactttt tccaaatttt
    20581 gtttgtgaaa attctaactt tatggtatta taataacatg aaaatgaaat gtaagggctt
    20641 caatttagat gattatttga tattacaact tattttctat aagagaaagg agttggtagc
    20701 ttgactcttc gttcacattc tgaacggcta atggggacta ctatcactat ttcattagtg
    20761 gatgagcaag ccgatatctt tctccaaaaa tcctttgact tgctcaaaga acttgaatac
    20821 cgcttcaacg ccaatagtca agaatctgag ttgatggaaa tcaattatca agcaggaata
    20881 gcccccgtca cggttcatcc agacctgttt gagctgattt cacttgggtt agagcatagc
    20941 ctagcgctct ctagccacct caatatcagc attggtccct taattcaaac ctggcgtatc
    21001 ggtttttcag atgccaaggt cgcccagcct caagaaattg aatcggtgct gcctctaatc
    21061 aatcctcatg gtatcgagtt agattcttct acttctactg tgtttttaaa acagaaagga
    21121 atgaagatcg atctaggttg tttagccaaa ggatacagtg cggataaggt tgcccaattt
    21181 cttaggaaag agggggtgac ttctgccttg atcaatctgg gagggaatat cctgaccatt
    21241 ggaaaaaatc aggcaagagg ggataaccca tggcaaatcg ggattcaaga cccagccaat
    21301 cctaggggaa atcatttaat gaccatccct gttgtcaata aatctgtcgt gacttcaggc
    21361 atttatgaac gtcacctgac cgtcgatgga caagattacc atcacatttt tgacagtcaa
    21421 acaggatatc ctgttgaaac ggaactagcg agtctaacaa tcatctctga taaatcagtc
    21481 gatggcgaaa tctggacgac tcgactcttt ggagaaagac ctgcttctat cctctggcaa
    21541 gtcgaaagtt tggagggcat cgaagtcatc ctcatcgata aagaaggcca cctaagctgt
    21601 tcttcaggaa ttcctactct atagagacaa ctgtttcaat ggaattttaa aattgtatta
    21661 tgtaaaaaga gaaaggaaat ctcatgttaa aacttattgc tattgttgga acaaattcaa
    21721 aacgttctac aaaccgtcaa ttgcttcaat acatgcaaaa acacttttct gacaaagctg
    21781 aaattgagct tgttgaaatc aaggccattc ctgtcttcaa caaaccagct gacaagcaag
    21841 tacctgctga aatattggaa attgctgcta aaatcgaaga ggcagatggc gttattatcg
    21901 gtactcctga gtatgatcac tctattccag ctgttttgat gagcgctctt gcttggttgt
    21961 cttatggtat ttacccactt ttgaacaaac caatcatgat tacaggtgct tcttacggta
    22021 cgcttggttc atctcgtgcc caattgcaac ttcgtcaaat cttgaatgct cctgaaatca
    22081 aggcaaatgt tcttccagat gaattcttgc tctcacactc tcttcaagca tttaacccaa
    22141 gtggcgactt ggttgacctt gatgttatca agaaattgga tgccatcttt gatgacttcc
    22201 gtatctttgt aaaaatcaca gaaaaattac gtaatgcaca agaattactt cgcaaagatg
    22261 ctgaagactt tgactgggaa aatttgtaag ataggagacc aaaaagaatg aaatttgttg
    22321 gacttgttgg atcaaactac gatcaatcat ataaccgtaa gctcttggaa tttatccgtc
    22381 gctacttcaa actcaaattt gaattagaag ttcttgaaat tgacgaagtt ccaatgttta
    22441 accaagatga aaaatgggat gaaagtttcc aattacgtta tttatataac aaaattactc
    22501 gtgcagatgg tgttatcatt gctactcctg agcataacca cactatctca gcttcactca
    22561 aatctgtact tgaatggctt tcatacgaag ttcatccatt tgaaaacaag cctgttatga
    22621 ttgtgggtgc atcatactat gaccaaggaa catcacgtgc tcaagttcac cttcgtaaaa
    22681 tccttgatgc tccaggtgtt aatgcctaca cgcttccagg taacgaattc cttcttggta
    22741 aagctaagga agcttttgat aacaacggaa atatcaccaa cgaaggcact gttaaattcc
    22801 ttgaaacttg cttagataac tttgttaaat acgtaggagt cgtttcgaaa ttgaaaaaac
    22861 caaaaccaat cgaatcagaa gacttggatt gtggaaaacc aatcgctaca accatcacag
    22921 aagttgaccc tgacgatcca gaatgggtag aaaaagttgc agcaatcact ggtgctgttt
    22981 ctggtgatac ctatgtcaaa ttggaccacg gtatcctaac agttaaccaa attgatatgt
    23041 tcttgaaagc tatgccattt gaattgacat acgctgacga caacaaccaa ttcctctact
    23101 acaacaacgc tcaccaagat ccagacacta tgttcgctaa acgtgtacca cctcaatcag
    23161 gtagccgtat gtcgactgtt catggttctc ttccaccagc acgtatgaag aacgtagagt
    23221 gggttatcgg aacacttcgc aacggaaacc aagaatacgt ccgtacgatc gttccaggtt
    23281 ctcctgcagg tgttatcaac actcacaact accaagcaat gtactatcct gatggatcat
    23341 acgctggtat caatgaaatc gtctttaact tccaaccatg gcttgactgg tacctaaaag
    23401 agactggtca acgtttggtg ggtggtagcg gaccatttgc tcctgctgcc ggaggtcatg
    23461 gagacgccga tgctacttct ggcgcttctg attcagggga tgctggaggc cacggtggtg
    23521 acgcagacgc tacagccggt gcaagttact aatgatagtt tttaggaacc attatggttc
    23581 cttttttagc gaaaaaagac tagcaaacac aaactgctag tctctttgtt atcgtttcat
    23641 ctatctttgt taaaagaaag agtacttata ctcaatgaaa atcaaagagc aaactaggaa
    23701 gctagccgca ggctgtactt aagtacggca aggtgaagct gacgtggttt gaatttgatt
    23761 ttcgaagagt attattatga atttgggtca tcaagactac ggccatgtaa tcctttttca
    23821 cgttgtactt ggcgtagttt ttctggtgta acatcgtttc cttcttcgtc cacaattttg
    23881 attccttcaa tgtggtgacg aacagcgcgg cgataacctt cgatgtactc ctcacgtagt
    23941 ttggcttgtt ccactttttc ttctgatgtt aagccttctg tttttttctt tttagcaagc
    24001 tcattgatac gagcaatttt tttcggatcc atttcttctc ctttgtaata agataaagtc
    24061 cgtttatcaa attttattta gtgttaattt ggttaaaaca agcaaactta gctgctttct
    24121 tggttagttg tgacaagatt gccaaacgat tttgacggac agcctgatct tcagccatta
    24181 ccatagtatt ttcaaagaaa gcatcaatga ctgggctaag cgcaaagagt tgtttcaatt
    24241 gctgacttgc aggtcctgat aaaacgagtg tttctactgc ttctgccaaa gctttttctt
    24301 ggtcattctc aaatagtgct gaatcaactg tagcaacccc ttctgccttc tcagccaggt
    24361 taaaggcacg agaaagtgat tcaacagatg gtttaaaata ttcttccttg cttacttcta
    24421 cgagagcact tgctgcttcc aacatatctg ccacaacaaa gtttgaacct gcaagaactg
    24481 cttccttgat atcttttgga gtagagccca tcatcttatc aacacgagcc ttgataaagt
    24541 ccataacctc tgctttattt tcataagtca aactgtcaaa tttcaatgca taaaggctat
    24601 caatcagctc atccatagca atgtgccaac caaaggcatc caagatacga accacacctt
    24661 gagttgcacg acgaagggca taagggtcat tagaacctga tggaatcaat cctactgaga
    24721 agaaactcaa aatcgtatcc aatttgtctg caatggctag aactgcgccg accttgctct
    24781 ctggaagttc tccttcagct gatgtaggca tgtagtgttc acgaatagca gctgccaccg
    24841 ctggagtttc accagcaaga agggtgtatt tttcacccat aattccttgg agttcgtcaa
    24901 attcaccaac catacctgtc aataagtcaa acttgtaaat ggctgctgca cgagcaaggt
    24961 caactgtttc atccactgac aaaccagctt tttctgccaa aagtacagtg atttgacccg
    25021 tacgaatcat gtgttcacga agggaaccaa tcttctcatg gaaggtgaca ttgtttaatt
    25081 tttcaacaag atctgaaatc accaattttt ggtcttcacg ccagaagaat tctccgtctt
    25141 ccaagcgggc taccaagact ttttcatttc ctttaatgac atttttcaaa cgctctgcgt
    25201 ttccgttacg aacagaaatg aagtttggca agagttttcc atcttgatca cgaacaacaa
    25261 agtaacgctg gtgttccttc atagaagtca ccaagacttc ttctggaact tcaaggtatt
    25321 tagcatcaaa acttcccatg aaggcagttg ggtattcaac caaattcaag acttcattca
    25381 gcaaatccgc atcaatttcg atacgtacac catgttttgc ctcaatttcc ttgatttggt
    25441 caacaatcat ttgctcacgt tcacatggat ctgcgattac aaactgctta cgaaggtctt
    25501 cttcatagct caatgctgac tgaattttgg tttctttccc caagaaacaa tggccacggc
    25561 tcacacgact tcccttgata tcaaggaaat ccaagtcaaa ctcttgctca tccaagagaa
    25621 cagttaaagt gtggacagga cgaatgtatt caaagctatt tccagcccag tgcatgctga
    25681 cagggaaagt caatgacttc aagacatcta caacaccagg aacaatggct tcaactgctt
    25741 gaccaacttc ttccttagtg acatagacat attcttcacc cttgatttca cggaattcga
    25801 tatcttcaac agtcaagcct tttccacgga caaatccttg agctgctttg gtaaagtttc
    25861 catcactatc caaggcaatt ttctttgctg gtcccttgaa atcttctgtc aaatcagact
    25921 gtttgtctga taaaccagtc acacgaacag ccaaacgacg tggtgttgag aaggtttgaa
    25981 tggcttcaaa agacaggcgg ttttccttga ggaaggctgc cattttttcg cctagttgtt
    26041 tttcacttgg tgtgacaaca taggctggta attcttcaag accgagttct actaataagt
    26101 tttttgtcat gttttttcct ttacattttc ttcaatcttt tttgatatgc accttaggta
    26161 ctggggacgt cgctaactaa ctctgtgagt ctgtatggaa atccaatgct aaatttatca
    26221 agatttccaa caatctcatc aaagtggatt tagctgactg atttttgaac ctaaggtttc
    26281 aaaaatcccc acataacagt acggcggtgc atatccctct agcaagtctt cgacttgcct
    26341 ctaacgattt tagagtacag tattactcac tattctgcgt cttctgctaa aagtttaact
    26401 cgtgtttctt catccaaaag tgggtaacct aggcgtttgc gttctgcaac aaaggttttg
    26461 gctacaacac gggccaagtt acggatacga gcgatatagc ctgcacgctc tgttacagat
    26521 acggcaccac gcgcgtcaag cagattaaag gtatgtgaac atttgagaac atagtcatag
    26581 gcagggtgta ccaagccttc ttctaatgca cgaccagctt ctttttcaaa cttatcaaag
    26641 ttttcaagca aaatttcttg gtccgaaatt tcaaatgaat attttgagtg ctcatactca
    26701 ggctggataa agatttctcc gtattttaca ccatcagccc actcgatatc atagacagag
    26761 tctacttctt gaatgtaaga agccaagcgc tccaaaccat aggtaacttc cgcagtcaca
    26821 gggccagttg ccaatccacc gacttgttgg aaataagtga actgagtgat ttccattccg
    26881 tcaagccaaa cttcccaacc aagaccagct gaaccagttg atgggttttc ccagttgtcc
    26941 tcaacaaaac gaatatcgtg ctccaaagga ttgattccca atttttccaa agactcaagg
    27001 taaagttctt ggatatttga tggagaaggc ttcatgacca cctggaattg gtggtgttgg
    27061 tagagacggt tagggttttc cccataacga ccgtcagcag gacgacgtga tggctctaca
    27121 taagctgcat tccatggctc aggtccgata gcacgaagga aagtgtaagg actcattgtc
    27181 cccgcacctt tttcattgtc ataagcctgc ataagcatac aaccttggtc attccaaaat
    27241 tgttgcaaag tcaaaataat ttcttgaaat gttaatttct tagacattgt ttactcctta
    27301 ataaaaaatg atttcttgcg acacgagtct
//
LOCUS       DAVBOD010000021        26014 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 640-05
            SAMEA1012484-rid20186543.denovo.021, whole genome shotgun sequence.
ACCESSION   DAVBOD010000021 DAVBOD010000000
VERSION     DAVBOD010000021.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012484
            Sequence Read Archive: ERR059358
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 26014)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26014)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979948.1
            Genome Coverage       :: 595x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:03:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,266
            CDSs (total)                      :: 2,219
            Genes (coding)                    :: 2,091
            CDSs (with protein)               :: 2,091
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 71 of 128
            Pseudo Genes (incomplete)         :: 50 of 128
            Pseudo Genes (internal stop)      :: 33 of 128
            Pseudo Genes (multiple problems)  :: 22 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26014
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012484-rid20186543.denovo.021"
                     /strain="NIG 640-05"
                     /db_xref="taxon:1313"
     gene            complement(15..311)
                     /locus_tag="VQ862_001034"
     CDS             complement(15..311)
                     /locus_tag="VQ862_001034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000239014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3115396.1"
                     /translation="MVKINKICSIQGSSVENEDIVGSQNQYFWIIGGATDLYNSKEEI
                     GYSVSEVVHILSESLSVNCKESKTLKQIFETALLEVKDEIGLNSYELTEYSKMK"
     gene            complement(295..2454)
                     /gene="pfbA"
                     /locus_tag="VQ862_001035"
     CDS             complement(295..2454)
                     /gene="pfbA"
                     /locus_tag="VQ862_001035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010976622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multi-ligand-binding adhesin PfbA"
                     /protein_id="HET3115397.1"
                     /translation="MLKIVKKLEVLMKYFVPNEVFSIRKLKVGTCSVLLAISILGSQG
                     ILSDEVVTSSSPMATKESSNAITNDLDNSPTVNQNRSAEMIASNSTTNGLDNSLSVNS
                     ISSNGTIRSNSQLDNRTVESTVTSTNENKSYKEDVISDRIIKKEFEDTALSVKDYGAV
                     GDGIHDDRQAIQDAIDAAAQGLGGGNVYFPEGTYLVKEIVFLKSHTHLELNEKATILN
                     GINIKNHPSIVFMTGLFTDDGAQVEWGPTEDISYSGGTIDMNGALNEEGTKAKNLPLI
                     NSSGAFAIGNSNNVTIKNVTFKDSYQGHTIQIAGSKNVLVDNSRFLGQALPKTMKDGQ
                     IISKESIQIEPLTRKGFPYALNDDGKKSENVTIQNSYFGKSDKSGELVTAIGTHYQTL
                     STQNPSNIKILNNHFDNMMYAGVRFTGFTDVLIKGNRFDKKVKGESVHYRENGAALVN
                     AYSYKNTKDLLDLNKQVVIAENIFNIADPKTKAIRVAKDSAEYLGKVSDITVTKNVIN
                     NNSKETEQPNIELLRVSDNLVVSENSIFGGKEGIVIEDSKGKITVLNNQFYNLSGKYI
                     SVIKSNANGKEPVIRDSDGNFNIVTENGLYKIVTNNLSDKNEKEKNKEEKQSNSNNVI
                     DSNQKNGEFNSSKDNRQMNDKIDNKQDNKTEEVNYKIVGDGRETENHINKSKEIVDVK
                     QKLPKTGSNKIMELFLTVTGIGLLLTLKGLKYYGKDK"
     gene            complement(3584..4810)
                     /locus_tag="VQ862_001036"
     CDS             complement(3584..4810)
                     /locus_tag="VQ862_001036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001134527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegT/DnrJ/EryC1/StrS aminotransferase family
                     protein"
                     /protein_id="HET3115398.1"
                     /translation="MPNYNIPFSPPDITEAEIAEVADTLRSGWITTGPKTKELERRLS
                     LYTQTPKTVCLNSATAALELILRVFEVGPGDEVIVPAITYTASCSVITHVGATPVMVD
                     IQADTFEMDYDLLEQAITEKTKVIIPVELAGIVCDYDRLFQVVEKKRDFFTASSKWQK
                     AFNRIVIVSDSAHALGSTYKGQPSGSIADFTSFSFHAVKNFTTAEGGSATWKANPVID
                     DEEMYKEFQILSLHGQTKDALAKMQLGSWEYDIVTPAYKCNMTDIMASLGLVQLDRYP
                     SLLQRRKDIVDRYDSGFAGSRIHPLAHKTETVESSRHLYITRVEGASLEERNLIIQEL
                     AKAGIASNVHYKPLPLLTAYKNLGFDMTNYPKAYAFFENEITLPLHTKLSDEEVDYII
                     ETFKTVSEKVLTLSKK"
     gene            complement(4853..5545)
                     /locus_tag="VQ862_001037"
     CDS             complement(4853..5545)
                     /locus_tag="VQ862_001037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000922225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HET3115399.1"
                     /translation="MLKWEDLPVEMKSSEVESYYQLVSKRKGSLIFKRCLDWVLALVL
                     LVLTSPIFLILSIWIKLDSKGPVIYKQERVTQYNRRFKIWKFRTMVTDADKKGNLVTS
                     ANDSRITKVGNFIRRVRLDELPQLVNVLKGEMSFVGTRPEVPRYTEQYSTEMMATLLL
                     QAGITSPASINYKDEDTIISQMTEKGLSVDQAYVEHVLPEKMRYNLAYLREFSFFGDI
                     KIMFQTVFKVLK"
     gene            complement(5731..7482)
                     /locus_tag="VQ862_001038"
     CDS             complement(5731..7482)
                     /locus_tag="VQ862_001038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001180175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3115400.1"
                     /translation="MQNKQEQWAVLKRLMSYLKPYRLLTFLALSFLLATTVIKSVIPL
                     VASHFIDQYLSNLNQLAVTVLLVYYGLYILQTVVQYVGNLLFARVSYSIVRDIRRDAF
                     ANMEKLGMSYFDKTPAGSIVSRLTNDTETISDMFSGILSSFISAVFIFLTTLYTMLVL
                     DFRLTALVLLFLPLIFLLVNLYRKKSVKIIEKTRSLLSDINSKLAENIEGIRIIQAFN
                     QEKRLQAEFDEINQEHLVYANRSVALDALFLRPAMSLLKLLGYAVLMAYFGYRGLSIG
                     ITAGTMYAFIQYINRLFDPLIEVTQNFSTLQTSMVSAGRVFALVDERTYEPLQENGQA
                     KVQEGNIRFEHVCFSYDGKHPILDDISFSVNKGETIAFVGHTGSGKSSIINVLMRFYE
                     FQSGRVLLDDVDIRDFSQEELRKNIGLVLQEPFLYHGTIKSNIAMYQEISDEQVQAAA
                     AFVDADSFIQELPQGYDSPVSERGSSFSTGQRQLLAFARTVASQPKILILDEATANID
                     SETESLVQASLAKMRQGRTTIAIAHRLSTIQDANCIYVLDKGRIIESGTHEELLALGG
                     TYHKMYSLQAGAMAYTL"
     gene            complement(7472..9217)
                     /locus_tag="VQ862_001039"
     CDS             complement(7472..9217)
                     /locus_tag="VQ862_001039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HET3115401.1"
                     /translation="MSIIQKLWWFFKLEKHRYLVGIVALVLVSVLNLIPPMVMGRVID
                     AITSGQLTQQDLLLSLFYLLLAAFGMYYLRYVWRMYILGTSYCLGQIMRSRLFKHFTK
                     MSPAFYQTYRTGDLMAHATNDINALTRLAGGGVMSAVDASITALVTLLTMLFSISWQM
                     TLVAILPLPFMAYATSRLGRKTHKAFGESQAAFSELNNKVQESVSGIKVTKSFGYQAD
                     ELKSFQAVNELTFQKNLQTMKYDSLFDPMVLLFVGSSYVLTLLVGSLMVQEGQITVGN
                     LVTFISYLDMLVWPLMAIGFLFNTTQRGKVSYQRIENLLSQESPVQDPEFPLDGIENG
                     RLEYAIDSFAFENEETLTDIHFSLAKGQTLGLVGQTGSGKTSLIKLLLREYDVDKGAI
                     YLNGHDIRDYRLTELRSLMGYVPQDQFLFATSILDNIRFGNPNLPLSEVEEATKLARV
                     YQDIVDMPQGFDTLIGEKGVSLSGGQKQRLAMSRAMILNPDILILDDSLSAVDAKTEY
                     AIIDNLKETRKDKTTIITAHRLSAVVHADFILVLQNGQIIERGRHEDLLAMDGWYAQT
                     YQSQQLEMKGEEDAE"
     gene            complement(9423..9719)
                     /locus_tag="VQ862_001040"
     CDS             complement(9423..9719)
                     /locus_tag="VQ862_001040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001276342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF421 domain-containing protein"
                     /protein_id="HET3115402.1"
                     /translation="MSASDVALKLRSQGIFQMKQVKRAVQEQNGQLIVVQMGDENPKY
                     PVVTDGVIQVDVLESIGRSEEWLLDNLSKQGHDNVANIFIAEYDKGAVTVVTYE"
     gene            complement(9872..10328)
                     /locus_tag="VQ862_001041"
                     /pseudo
     CDS             complement(9872..10328)
                     /locus_tag="VQ862_001041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730499.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3290 family protein"
     gene            10461..11288
                     /gene="xth"
                     /locus_tag="VQ862_001042"
     CDS             10461..11288
                     /gene="xth"
                     /locus_tag="VQ862_001042"
                     /EC_number="3.1.11.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006596696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease III"
                     /protein_id="HET3115403.1"
                     /translation="MKLISWNIDSLNAALTSDSARAKLSQEVLQTLVAKNADIIAIQE
                     TKLSAKGPTKKHVEILEELFPGYENTWRSSQEPARKGYAGTMFLYKKELTPTISFPEI
                     GAPSTMDLEGRIITLEFDAFFVTQVYTPNAGDGLKRLEERQVWDAKYAEYLAELDKEK
                     PVLATGDYNVAHNEIDLANPASNRRSPGFTDEERAGFTNLLATGFTDTFRHVHGDVPE
                     RYTWWAQRSKTSKINNTGWRIDYWLTSNRIADKVTKSDMIDSGARQDHTPIVLEIDL"
     gene            11300..11443
                     /locus_tag="VQ862_001043"
     CDS             11300..11443
                     /locus_tag="VQ862_001043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase"
                     /protein_id="HET3115404.1"
                     /translation="MDYNAVIPELLVSNIEQSRSFYCGLLGFRIEYQRPEENFLFLLK
                     SVN"
     gene            11443..11682
                     /locus_tag="VQ862_001044"
     CDS             11443..11682
                     /locus_tag="VQ862_001044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase"
                     /protein_id="HET3115405.1"
                     /translation="MLEEGTKDQLAELTYPFGRGVNLSFGIKDVSKLYQRVMKANYPI
                     YRPLTKRKFRVSDPYIYPHEFAVLDPDGYFLRFSE"
     regulatory      12065..12160
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            12560..13141
                     /locus_tag="VQ862_001045"
     CDS             12560..13141
                     /locus_tag="VQ862_001045"
                     /EC_number="2.4.2.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000770427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine phosphoribosyltransferase"
                     /protein_id="HET3115406.1"
                     /translation="MKLLEERILKDGHILGDNILKVDSFLTHQVDFSLMREIGRVFAE
                     KFAATGITKVVTIEASGIAPAVFTAEALNVPMIFAKKAKNITMNEGILTAQVYSFTKQ
                     VTSTVSIAGKFLSPEDKVLIIDDFLANGQAAKGLIQIIEQAGATVQAIGIVIEKSFQD
                     GRDLLEKAGYPVLSLARLDRFENGQVVFKEADL"
     gene            13141..14403
                     /locus_tag="VQ862_001046"
     CDS             13141..14403
                     /locus_tag="VQ862_001046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001194492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine permease"
                     /protein_id="HET3115407.1"
                     /translation="MQTQEKHSQAAVLGLQHLLAMYSGSILVPIMIATALGYSAEQLT
                     YLISTDIFMCGVATFLQLQLNKYFGIGLPVVLGVAFQSVAPLIMIGQSHGSGAMFGAL
                     IASGIYVVLVSGIFSKVANLFPSIVTGSVITTIGLTLIPVAIGNMGNNVPEPTGQSLL
                     LAAITVLIILLINIFTKGFIKSISILIGLVVGTAIAATMGLVDFSPVAVAPLVHVPTP
                     LYFGMPTFEISSIVMMCIIATVSMVESTGVYLALSDITKDPIDSTRLRNGYRAEGLAV
                     LLGGIFNTFPYTGFSQNVGLVKLSGIKKRLPIYYAAGFLVLLGLLPKFGALAQIIPSS
                     VLGGAMLVMFGFVSIQGMQILARVDFANNEHNFLIAAVSIAAGVGLNNSNLFVSMPTA
                     FQMFFSNGIVVASLLAIVLNAVLNHKKK"
     gene            complement(14490..15356)
                     /locus_tag="VQ862_001047"
     CDS             complement(14490..15356)
                     /locus_tag="VQ862_001047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000815109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II restriction endonuclease"
                     /protein_id="HET3115408.1"
                     /translation="MKQTRNFDEWLSTMTDTVADWTYYTDFPKVYKNVSSIKVALNIM
                     NSLIGSKNIQEDFLDLYQNYPEILKVVPLLIAKRLRDTIIVKDPIKDFYFDFSKRNYS
                     IEEYTMFLEKSGIFDLLQNHLVSNLVDYVTGVEVGMDTNGRKNRTGDAMENIVQSYLE
                     AEGYILGENLFKEIEQNEIEEIFSVDLSAITNDGNTVKRFDFVIKNEQVLYLIEVNFY
                     SGSGSKLNETARSYKMIAEEIKAIPNVEFMWITDGQGWYKAKNNLRETFDILPFLYNI
                     NDLEHNILKNLK"
     gene            complement(15343..16113)
                     /locus_tag="VQ862_001048"
     CDS             complement(15343..16113)
                     /locus_tag="VQ862_001048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific DNA-methyltransferase"
                     /protein_id="HET3115409.1"
                     /translation="MTKPYYNKNKMILVHSDTFKFLSKMKPESMDMIFADPPYFLSNG
                     GISNSGGQVVSVDKGDWDKISSFEEKHEFNRKWIRLAKEVLKPNGTVWISGSLHNIYS
                     VGMALEQEGFKILNNITWQKTNPAPNLSCRYFTHSTETILWARKNDKKARHYYNYDLM
                     KELNDGKQMKDVWTGSLTKKVEKWAGKHPTQKPEYLLERIILASTKEGDYILDPFVGS
                     GTTGVVAKRLGRRFIGIDAEKEYLKIARKRLEAENETN"
     gene            complement(16139..16993)
                     /locus_tag="VQ862_001049"
     CDS             complement(16139..16993)
                     /locus_tag="VQ862_001049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012972462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA adenine methylase"
                     /protein_id="HET3115410.1"
                     /translation="MKIKEIKKVTLQPFTKWTGGKRQLLPVIRELMPKTYNRYFEPFV
                     GGGALFFDLAPKDAVINDFNAELINCYQQIKDNPQELIEILKVHQEYNSKEYYLDLRS
                     ADRDERIDMMSEVQRAARILYMLRVNFNGLYRVNSKNQFNVPYGRYKNPKIVDEELIS
                     AISVYINNNQLEIKVGDFEKAIVDVRTGDFVYFDPPYIPLSETSAFTSYTHEGFSFAD
                     QVRLRDAFKRLSDTGAYVMLSNSSSALVEELYKDFNIHYVEATRTNGAKSSSRGKISE
                     IIVTNYEK"
     gene            complement(17150..17554)
                     /locus_tag="VQ862_001050"
     CDS             complement(17150..17554)
                     /locus_tag="VQ862_001050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000651202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PaaI family thioesterase"
                     /protein_id="HET3115411.1"
                     /translation="MKDFHFDAISAFENYEIEKMRDGHVVVTTKVVNSSLNYYGNAHG
                     GYLFTLCDQISGLVVISLGLDGVTLQSSINYLKAGKLDDVLTIKGECVHQGRTTCVMD
                     VDITNQEGRNVCKATFTMFVTGQRSEERQVRI"
     gene            complement(17624..19105)
                     /locus_tag="VQ862_001051"
     CDS             complement(17624..19105)
                     /locus_tag="VQ862_001051"
                     /EC_number="2.7.7.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose--hexose-1-phosphate
                     uridylyltransferase"
                     /protein_id="HET3115412.1"
                     /translation="MTLVDKFVTHVISESSFEEMDRIYLTNRVLARVGEGVLEVETNL
                     DKLIDLKDQLVEEAVRLETIEDSQTAREILGTELMDLVTPCPSQVNRDFWEAYAYSPE
                     QAIEDFYQLSRKNDYIKLKAIAKNIAYRVPSDYGELEITINLSKPEKDPKEIAVAKLV
                     QASNYPQCQLCLENEGYHGRVNHPARSNHRIIRFEMVGQEWGFQYSPYAYFNEHCIFL
                     DGQHRPMAISRQSFERLLAIVEQFPGYFAGSNADLPIVGGSILTHDHYQGGRHVFPME
                     LAPLQKTFRFAGFEQVKAGIIKWPMSVLRLTSDSKEDLINLADKIFQEWRQYSDSSVQ
                     ILAETDGTPHHTITPIARKRDGQFELDLVLRDNQTSAEHPDGIYHPHKDVQHIKKENI
                     GLIEVMGLAILPPRLKEEVEQVASYLVGEAVTVADYHQEWADQLKSQHPDLTDKEKAL
                     AIVKDSVGAIFVRVLEDAGVYKQTEQGQTAFMRFVEQVGILLD"
     gene            complement(19124..20302)
                     /locus_tag="VQ862_001052"
     CDS             complement(19124..20302)
                     /locus_tag="VQ862_001052"
                     /EC_number="2.7.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000047000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactokinase"
                     /protein_id="HET3115413.1"
                     /translation="MTQHLTAETLRKDFLAVFGQEADQTFFSPGRINLIGEHTDYNGG
                     HVFPAAISLGTYGAARKRDDQVLRFYSANFEDKGIIEVPLADLKFEKEHNWTNYPKGV
                     LHFLQEAGHVIDKGFDFYVYGNIPNGAGLSSSASLELLTGVVAEHLFDLKLERLDLVK
                     IGKQTENNFIGVNSGIMDQFAIGMGADQRAIYLDTNTLEYDLVPLDLKDNVVVIMNTN
                     KRRELADSKYNERRAECEKAVEELQVALDIQTLGELDEWAFDQYSYLIKDENRLKRAR
                     HAVLENQRTLKAQAALQAGDLETFGRLMNASHVSLEHDYEVTGLELDTLVHTAWAQEG
                     VLGARMTGAGFGGCAIALVQKDTVEVFKEAVGKHYEEVVGYAPSFYIAEVAGGTRVLD
                     "
     gene            20466..21473
                     /gene="galR"
                     /locus_tag="VQ862_001053"
     CDS             20466..21473
                     /gene="galR"
                     /locus_tag="VQ862_001053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000212522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator GalR"
                     /protein_id="HET3115414.1"
                     /translation="MATLKDIAQLASVSIATVSRVLNRDQSLSVTEETRHRILTVAEE
                     LGYTKHLKTGESHKPKQKIAIIQWVSEQGELDDLYYYQIRLGIEKRAQELDYDILRYF
                     NDHPFTLSEEVIGILCIGKFSRAQISAFEEYQKPLVFLDSDTLSLGHTCIITDFYTAM
                     KQVVDYFLSQGMDRIGILTGLEETTDQEEIIQDKRLENFRNYSQAKGIYHDELVFQGN
                     FTAQSGYDLMKEAIQSLGDQLPPAFFAASDSLAIGALRALQEAGISLPDRVSLISFND
                     TSLTKQVYPPLSSITVYTEEMGRAGMDILNKEVLHGRKIPSLTMLGTRLTLRESTLNQ
                     E"
     gene            complement(21519..22556)
                     /locus_tag="VQ862_001054"
     CDS             complement(21519..22556)
                     /locus_tag="VQ862_001054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000833740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase catalytic
                     domain-containing protein"
                     /protein_id="HET3115415.1"
                     /translation="MKSAVYTKAGQVGLASIERPQIIEADDVIIRVVRACVCGSDLWR
                     YRNPETKAGHKNSGHEAIGIVEEAGEAITTVKPGDFVIVPFTHGCGECDACLAGFDGS
                     CDNHIGNNLGGDFQAEYIRFHYANWALVKIPGQPSDYTEGMLKSLLTLADVMPTGYHA
                     ARVANVQKGDKVVVIGDGAVGQCAVIAAKMRGASQIILMSRHEDRQKMAMESGATAVV
                     AERGQEGITKVREILGGGADAALECVGTEAAIEQALGVLHNGGRMGFVGVPHYNNRAL
                     GSTFMQNISVAGGAASATTYDKQFLLKAVLDGDINPGRVFTSSYKLEDIDQAYKDMDE
                     RKTIKSMIVIE"
     gene            complement(22557..22910)
                     /locus_tag="VQ862_001055"
     CDS             complement(22557..22910)
                     /locus_tag="VQ862_001055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HET3115416.1"
                     /translation="MNIKSASDLLGISADTIRYYERVGLVPPITRTATGIRDFQDQDI
                     EALEFIKCFRSAGVSVDSLVDYMSLYQKGDETREERLGILEEEKQKLEERLSQLQTAL
                     NRLNLKIKLYKEGKF"
     gene            complement(23154..24044)
                     /locus_tag="VQ862_001056"
     CDS             complement(23154..24044)
                     /locus_tag="VQ862_001056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000645104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HET3115417.1"
                     /translation="MKAKYAVWVAFFLNLTYAIVEFIAGGVFGSSAVLADSVHDLGDV
                     IAIGISAFLETISNREEDNQYTLGYKRFSLLGALVTAVILVTGSVLVILENVTKILHP
                     QPVNDEGILWLGIIAITINLLASLVVGKGKTKNESILSLHFLEDTLGWVAVILMAIVL
                     RFTDWYILDPLLSLVISFFILSKALSRFWSTLKIFLDAVPEGLDIKQVKSGLERLDNV
                     ASLNQLNLWTMDALEKNAIVHVCLKEMEHMETCKESIRIFLKDCGFQNITIEIDADLE
                     THQTHKRKVCDLERSYEHQH"
     gene            24177..24713
                     /locus_tag="VQ862_001057"
     CDS             24177..24713
                     /locus_tag="VQ862_001057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HET3115418.1"
                     /translation="MTNIDRRISKTKKAIYQAFIQLLNAKGYEATTVQDIIDLADVGR
                     STFYCHYESKELLLDQLCRYLFHHLFEREQAISTEDYLAHLFLHFHKNQDHITSLLFS
                     KNDYFLRQLHKELEHHVYSVLADNLKEAHPNMPTSYLQHLVVSNFIETLTWWLKKGQD
                     FTDQEVVQFYLDLLIPKN"
     gene            complement(24879..25685)
                     /locus_tag="VQ862_001058"
     CDS             complement(24879..25685)
                     /locus_tag="VQ862_001058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide riboside transporter PnuC"
                     /protein_id="HET3115419.1"
                     /translation="MHTYLQKKIENIKTTLGEMSGGYRRMVAAMADLGFSGTMKAIWD
                     DLFAHRSFAQWIYLLVLGSFPLWLELVYEHRIVDWIGMICSLTGIICVIFVSEGRASN
                     YLFGLINSVIYLILALQKGFYGEVLTTLYFTVMQPIGLLVWIYQAQFKKEKQEFVARK
                     LDGKGWTKYLSISVLWWLAFGFIYQSIGANRPYRDSITDATNGVGQILMTAVYREQWI
                     FWAATNVFSIYLWWGESLQIQGKYLIYLINSLVGWYQWSKAAKQNTDLPN"
BASE COUNT         7804 a         5737 c         4612 g         7861 t
ORIGIN      
        1 gatttgtcct attattattt cattttacta tactctgtta attcatatga gtttaaaccg
       61 atttcatctt taacctcgag taaagcagtt tcaaatattt gtttaagagt ttttgattct
      121 ttacaattaa ccgacaaact ttctgataaa atatgtacaa cttctgagac tgaataacct
      181 atctcctctt tagaattata taaatctgta gctccaccaa taatccaaaa atactgattt
      241 tgtgaaccta caatatcctc attttctacg gaacttcctt gtatcgaaca aattttattt
      301 atctttacca taatacttca acccttttag tgtcaaaagt aaaccaattc ctgtcactgt
      361 taagaatagt tccataatct tgttcgaacc agtctttggt aatttttgtt ttacatctac
      421 tatttcttta gatttattaa tatgattttc agtttctctg ccatctccaa ctattttata
      481 gtttacttct tctgtcttat tatcttgttt attgtcgatc ttgtcattca tttgtctatt
      541 atctttactt gagttaaact ctccgttctt ctggttacta tcaattacat tatttgaatt
      601 agattgtttt tcctctttgt ttttttcttt ttcgttttta tcacttaaat tatttgttac
      661 aattttgtaa agcccattct ccgttacaat attgaaatta ccatcgctat cacgtataac
      721 aggttctttc ccatttgcat tagatttgat gactgatata tacttaccgg ataaattata
      781 aaattggtta tttaaaacgg ttattttacc ctttgaatcc tcaataacaa ttccttcttt
      841 accaccgaat atactattct ctgagactac taaattatca ctaactcgta ataattcaat
      901 atttggttgt tctgtttcct tagaattatt attaattaca ttttttgtta cagtaatatc
      961 tgatactttt cctaaatatt ctgcactatc ttttgcaact cgtatcgctt ttgttttagg
     1021 atcggcaata ttaaatatat tttcggcgat aaccacctgt ttatttaaat ctaataggtc
     1081 tttagtgttt ttatagctat aagcatttac taaagctgct ccgttttctc gataatgtac
     1141 actctctcct ttaactttct tatcaaagcg atttcctttg attaatacat cagtgaatcc
     1201 tgtaaaacgt acacctgcat acatcatgtt atcaaaatga ttatttaaaa ttttaatatt
     1261 agaggggttc tgtgtcgaca atgtttgata gtgtgtacca attgctgtta ctaattcccc
     1321 agatttatca cttttgccaa aataggaatt ttgaatagtc acattttcag attttttccc
     1381 atcatcattc aaggcataag gaaaaccttt tctagttaat ggttcaatct gaatgctctc
     1441 cttacttatg atttgcccat ccttcatcgt tttgggtaag gcttgcccaa gaaaacgaga
     1501 attatcaact aatacatttt tcgaacctgc aatttgaata gtatgccctt gataactatc
     1561 cttgaatgtt acatttttta tagttacgtt atttgaattc ccaatagcaa atgcacctga
     1621 agaatttata agtggtagat tttttgcttt agttccttct tcattcaaag caccgttcat
     1681 atcaatcgta ccaccagaat aactaatatc ttctgttggg ccccattcta cttgcgcacc
     1741 atcatccgta aataaacctg tcataaaaac aatggaaggg tgattcttaa tatttatacc
     1801 atttagaatt gtagctttct cattcaattc taagtgtgta tgacttttta aaaaaacaat
     1861 ttcttttact aaataagttc cttcaggaaa atatacattt cctccaccta gcccttgagc
     1921 tgcagcatct attgcatctt gaattgcttg tcgatcatca tgaatcccat cacctaccgc
     1981 accataatct tttacactta aagcagtatc ttcaaattct tttttgataa ttctgtcact
     2041 tataacatct tccttataac tcttattttc attagtagat gttactgtag attcaactgt
     2101 tctgttgtct aattgtgaat tggaacgaat agtaccatta gagctgatac tattaacact
     2161 taacgaatta tctaaaccat tagtggttga attagaggca atcatttcag cagaacgatt
     2221 ctgattaaca gttggtgaat tatctaaatc attagtaatt gcattagaag actcttttgt
     2281 agccatcggt gaagaactag taacaacttc atccgataaa ataccttggc ttcccaaaat
     2341 tgaaattgcc aatagtaccg agcaagtccc cacctttaat ttacgaatac tgaatacctc
     2401 attaggaaca aaatatttca tcagaacctc caattttttt actattttta acaattgatt
     2461 attacttttc ttaaaataga tagaatgaca ccgctgtcat tatctttatc atatattttc
     2521 caaattgaat tgtcaaggaa taacacaaga aaatattaaa atttatactc ttcggaaatc
     2581 tcttcaaact aggtcagtgc cgccttgccc taagtctagg ttactgactt ggtcagttct
     2641 atagtaaatt gaaactaaaa tagtacacct ctacttctaa aacattgtta gaaatcgatt
     2701 tgactgtccc gatcaatttg tcctattctt atttcatttt actatatcta caacctcaaa
     2761 gcagggtttt gagctatcta tggccaactt cctagtttgc tctttagcct tccattcaaa
     2821 agtgatgcta tctttcttag cttgaatata aaatatccca tttactatat ttaaatttat
     2881 tgatatgttg taaattataa atgaaagaac aaataccttg tcatacaagc attcgccagg
     2941 gatatttaca tgaatatcgc tcatatggcg gattgaaact aaaacactac aatatatttc
     3001 ttaaatagac cttctataaa agctagattt aacctcgata aaaatagatg cagtgcttct
     3061 aaaatactgg aatagggcat ataggtaata gtagacaagt gttttataga ttgtctcgcg
     3121 ggagatctaa tgatgtatag caagcatcac taaacatata gaatatttgt gttattataa
     3181 tatcaatatg ctataaattc tatcatgcaa aagaatgact agaacatgaa agacaggcac
     3241 aaaactttga acaatattct gaaaacaaaa aaagacgcga gtttccacaa tctcactcat
     3301 ggaaactcac gtctttcaaa aaatagggtg aattaaaaac tagaacaaga cactagattt
     3361 tctaaatgat gtctagtaag gattctaaat gctacaccaa attgctcaca tcttatttca
     3421 aaccacggga ctcccacaag aaaggaaaat cctataaaaa ttctctctct gaggagagag
     3481 aggcctcaac tacaggtgta aactattatc aattgaaaac aacagttttt acactcaatt
     3541 agacttttta gggacaggat cactttcgct tgactgtagt ttgtcatttt tttgataaag
     3601 ttagcacttt ttcagaaact gttttgaaag tctcaatgat atagtctact tcttcatcgc
     3661 ttaatttagt atgaagaggg agggtaattt cattctcaaa gaaggcatag gccttaggat
     3721 agttcgtcat atcaaatcca agattcttat aggctgtcaa gagaggaagc ggtttgtagt
     3781 gaacattact tgcaattcct gctttagcca attcttggat gatgaggttg cgttcttcta
     3841 ggcttgctcc ttctacacgg gtgatgtaga ggtggcgtga agattcgaca gtttcagtct
     3901 tgtgtgccaa aggatggatg cgagaacctg caaaaccact atcatagcgg tccacaatat
     3961 ccttacggcg ttgcaacaaa cttggatagc ggtccaattg taccaaacca agtgaagcca
     4021 tgatatcggt catgttgcac ttataggctg gtgtaacgat atcgtattcc catgacccca
     4081 gttgcatctt ggcaagagca tccttagttt gcccgtgaag ggaaaggatt tggaattcct
     4141 tgtacatctc ttcgtcatca atcactggat tggctttcca agtcgcactt ccaccttctg
     4201 ccgttgtaaa gttcttaacg gcatggaatg agaaggaagt aaagtcagcg atagaaccag
     4261 aaggttgtcc tttataagta gatcccaaag cgtgggcact atcagagaca atgacaatac
     4321 ggttaaaggc cttttgccac ttgcttgaag cggtaaagaa gtcacgtttt ttctccacga
     4381 cttggaacaa acggtcataa tcgcaaacaa tccctgcgag ctctactggg ataatcacct
     4441 tagttttctc agtgatagct tgctcaagca ggtcatagtc catctcaaac gtatctgctt
     4501 ggatatccac catgacaggg gttgctccca cgtgcgtaat gacactacat gaagccgtat
     4561 aggttatggc tggaacgatg acttcatcac caggtcccac ttcaaaaacg cgtaaaatca
     4621 actccagagc ggctgtcgca gagttgagac aaacagtctt aggtgtctgt gtgtaaagag
     4681 acaagcggcg ctccagttct tttgttttag gacctgttgt gatccaacca gaacgcaggg
     4741 tatccgctac ttcagcaatt tctgcttctg tgatatcagg cggtgaaaat ggaatattgt
     4801 aatttggcat tgatttgctc cttttatctg tactcattct cttatgacta ctttatttta
     4861 gtaccttaaa cacggtttga aacatgattt tgatgtcccc aaagaaacta aactctcgga
     4921 gataggcgag gttatagcgc atcttttcag gaagaacatg ctccacatag gcctgatcaa
     4981 ctgacagacc tttctctgtc atttgactga tgatggtgtc ctcatccttg tagttgatgc
     5041 tggctggaga ggtaattcct gcttgcaaga gcaaggttgc catcatttca gtgctatact
     5101 gctctgtata acgtggcact tcaggtcgtg taccgacaaa ggacatctca cctttaagga
     5161 cattgaccaa ctgaggcagt tcgtccaaac ggacacgtcg gatgaaattt ccaaccttgg
     5221 taatacggct atcgttagca gaagtcacca gatttccttt tttatccgca tccgtcacca
     5281 tggtacggaa cttccaaatc ttgaaccgac ggttgtactg ggtcacacgc tcttgcttgt
     5341 aaatcactgg ccccttgcta tccaacttga tccaaatgct caagatgaga aagatgggag
     5401 aggtcagaac cagtaagacc aaggccaaaa cccagtccaa gcaacgcttg aaaatcagcg
     5461 aacccttcct tttagagaca agctggtagt aagactcaac ctcgcttgat ttcatttcca
     5521 caggcaagtc ttcccatttc agcatgctgt tctcctttgt ttttattata ctatttgtca
     5581 acactttttg tcaacacttt tcattatacc acaaaatgga aaaggcggtg aaaaaaatct
     5641 gtaatttgaa ggatttcctt ctagtactca atgaaaatca aagtacagct ttgagattgc
     5701 agataaagct gacatggttt aaagagattt tcaaagagta taggccatgg cccctgcctg
     5761 caaactatac atcttgtgat aggttcctcc cagagccaag agttcctcat gggttccact
     5821 ctcgataatg cgtcccttat ccaagacata gatgcagttg gcgtcttgaa tagtagaaag
     5881 gcggtgagct atagcaatag ttgttcggcc ctgtctcatc ttcgccagag aagcttgaac
     5941 caagctttct gtttcagagt caatattggc tgtcgcttca tccaaaatca ggattttagg
     6001 ctggctggcg actgttctag caaaggcaag aagctggcgt tgcccagtag agaagctcga
     6061 accacgctcg gaaacagggg agtcgtaccc ctgaggaagt tcttgaataa aggaatctgc
     6121 atccacaaag gctgccgcag cctgaacctg ctcatcactg atttcttggt acatggcgat
     6181 attggactta atagttccat gatagaggaa gggttcctgc aagaccaaac cgatgttttt
     6241 tctcagctct tcttgactga aatccctgat atccacatca tccaagagaa ctctccctga
     6301 ctggaattca taaaagcgca tgaggacatt gataatagac gatttccctg aacctgtatg
     6361 acctacaaag gcaatggttt cacccttatt aacagagaaa gaaatgtcat ccagaatcgg
     6421 atgtttaccg tcatatgaga aacacacatg ttcaaagcgg atattgcctt cttggacttt
     6481 ggcttgccca ttttcttgaa gaggttcata ggtcctctcg tctaccaggg caaagacacg
     6541 acctgcagaa accatagacg tttgcagtgt tgaaaagttt tgcgtcacct caatcaaagg
     6601 gtcaaagagg cggttgatgt actggataaa agcatacatg gtcccggccg ttatcccgat
     6661 agaaagacca cgatagccaa aataggccat caagacagca taacctagaa gtttcaacaa
     6721 actcatggca ggtctcaaaa agagggcatc caaggctaca gaacggttgg catagaccaa
     6781 gtgctcttgg ttgatttcat caaattctgc ctgcaggcgc ttctcttgat taaaggcctg
     6841 gattattctg attccctcga tgttttcagc cagcttgcta ttgatatctg acaagagact
     6901 tctggttttc tcaatgattt tcactgattt tttccgatag agattgacca aaaggaaaat
     6961 caaggggaga aagagcaaga ctaatgctgt caaacgaaaa tccaatacca acatggtata
     7021 aagggttgtc agaaagatga aaactgctga gataaagcta gataaaatcc cagaaaacat
     7081 atcactaatc gtctcggtat cgttggtcaa acgagaaacg atagaacctg ctggcgtctt
     7141 gtcaaagtaa gacatgccca gtttctccat attggcaaag gcatcccgac gaatatccct
     7201 aacaatactg taagacacgc gcgcaaagag aagattgccg acatactgaa ctacagtttg
     7261 taggatgtag agaccatagt agaccagcaa aacggtaacg gctagttggt taagattgct
     7321 gagatactgg tcgataaagt gggaagccac gaggggtatg acacttttaa tgaccgtcgt
     7381 cgctaggaga aaactgagtg ccaaaaaggt caggagtcta taaggcttga gataagacat
     7441 caagcgcttc aatacagccc attgttcttg tttattctgc atcttcttct cctttcattt
     7501 ctaactgctg agactggtag gtttgggcat accagccatc catcgctagc aagtcttcgt
     7561 gcctgcctcg ttcgataatt tgaccatttt gtagaactaa aataaaatct gcatggacaa
     7621 cagcactgag gcgatgggca gttataatgg ttgtcttgtc ctttcgcgtc tccttgaggt
     7681 tgtcgataat cgcatactct gtcttggcat ctacggcgga taaggaatca tccaaaatca
     7741 agatatcagg gtttaaaatc atagcccgac tcatagccaa ccgttgcttt tgaccaccag
     7801 aaagactgac tcctttttca ccaatcagcg tatcaaatcc ttgaggcatg tctacaatat
     7861 cttggtaaac tcgggctagc ttagtagctt cctcaacctc tgaaaggggc aagttaggat
     7921 tgccaaagcg gatattgtct aggattgaag tcgcaaagag aaactggtcc tgaggaacat
     7981 agcccatgag actgcgaagt tctgtcaaac gatagtcccg aatatcgtga ccgtttagat
     8041 aaatggcacc cttatccaca tcgtattcac gcaagaggag cttgattaag gacgttttcc
     8101 cagagcctgt ctgcccaacc aagcccagtg tttgcccttt tgccaaacta aagtgaatat
     8161 ccgtcagtgt ttcctcattt tcaaaagcaa agctgtcaat ggcatactcc aaacgcccat
     8221 tttcaatacc atccagagga aactcagggt cttgtacagg agattcctga gacaaaagat
     8281 tttcaatccg ctggtaagaa accttccctc gctgagtagt attaaagagg aagccgatgg
     8341 ccataagagg ccagaccagc atatccaaat agctgataaa ggtgactaga ttaccaactg
     8401 taatctgccc ttcctgaacc atcaaggagc caaccaaaag cgttaaaaca taggacgaac
     8461 caacaaacaa gagaaccata gggtcaaaga gactatcata tttcatggtt tgcaggttct
     8521 tttggaaggt taattcattg actgcctgaa aagacttcaa ctcgtctgcc tgataaccga
     8581 aagacttggt cactttgata cctgatacgg actcctgtac cttgttattg agttcagaaa
     8641 aagcagcttg ggattcgcca aaggccttat gagtctttct ccctaggcga ctagtcgcat
     8701 aggccatgaa aggtaggggg agaatggcaa caagagtcat ctgccatgag atgctaaaga
     8761 gcatggtcaa caaagtcacc agagccgtga tagaggcatc caccgcagac atgacaccgc
     8821 cacctgctaa acgagtcaag gcattgatat cattggttgc gtgtgccatc agatcacccg
     8881 tccgataggt ttgataaaag gctggcgaca tttttgtgaa atgcttaaac aagcgagacc
     8941 gcatgatctg tcccaagcaa taagaggtcc caaggatata catacgccac acatagcgca
     9001 aatagtacat accaaaggct gcaagtagca agtaaaatag gctaagaagg aggtcctgct
     9061 gggttaattg ccccgatgtg atggcatcaa tgactcgccc cataaccata ggaggaatga
     9121 gattgagaac ggaaaccaag accagggcca caatcccgac tagataacgg tgtttttcta
     9181 acttgaaaaa ccaccagagt ttttgaataa tggacataaa atccctttct gattgcaaat
     9241 ggaaacctga ggccaatact caatgaaaat caaagagcaa actaggaaac tagccgcagg
     9301 ctgctcaaag cactgctttg aggttgtaga tagaactgac gaagtcagta acctacatac
     9361 ggcaaggcga cgttgacgcg gtttgaagag attttcgaag agtacaagac cccaggtttt
     9421 tcttattcat aagttacgac tgtaacagca cccttgtcat attcagcaat aaagatattg
     9481 gctacattgt catgcccttg tttgctgagg ttatcaagca accactcttc gctacgacca
     9541 atcgattcca agacgtctac ttgaatcaca ccgtcagtca caactggata cttaggattt
     9601 tcatctccca tttgcacaac gatgagttgc ccattttgct cttgcacagc tcgtttgact
     9661 tgcttcatct ggaaaatccc ttggctacga agtttgaggg ctacatccga tgcagacaaa
     9721 ccaactgaac gacaggctta tgggtcaata ttcccatttt tgataaggag agttggctta
     9781 ccatcaatca aacgtttcac aaagtgaaca ttgttgttga gctatttgag agtcaagatc
     9841 agtttgatta aaatttcgat ataattaagt gtcatttgtt cacatccacc agttcaattg
     9901 cgtctgtctt atacaattcg actttctcta acaggtactt gtctggctca cttccgttta
     9961 gggcacgata atagcgatct cccaccttga taagtgcgcc atctgtgttt gtggaagtat
    10021 taacatggac ttctgacttg tctactccca aatctttgga aacaacctcg atgaaatgaa
    10081 gtgaagtttg aaatttattg ttagaaactt gattgttttg ataagtcgtg atgctgacca
    10141 aaagcatagc taaataaggc cagagctgaa atcatgacca actcacgaaa tttggttcct
    10201 tttttatcat ggtatgcctt gaaagcaaaa aaaactgtca cagctaatag aacaatccca
    10261 aagccaacca tgataccatt ttgctgaccg atttggctga gtacatagtc ataagagtag
    10321 aatttcatgt attttcactc cctttcataa aatcattctt aattataaac gaaagagagt
    10381 aatttttcaa accatacgtt ggggaaatag ctcttttttt ggtataataa aatctataat
    10441 ctgaatgaaa aggtaacttt atgaaactta tctcatggaa tattgattcc ctaaacgctg
    10501 ccctaactag tgactcagct cgtgccaaat tgtcccaaga agtcctacaa accttggtcg
    10561 ctaaaaatgc tgatattatt gctatccaag aaaccaagct ttctgccaaa ggacctacaa
    10621 agaaacacgt ggaaatttta gaagaactct tcccaggcta cgaaaacacg tggcgttctt
    10681 cccaagagcc tgcccgtaaa ggctatgctg gaaccatgtt tctttataag aaagaactta
    10741 cacctactat cagcttccca gaaatcggtg ccccttctac catggacttg gaaggtcgta
    10801 tcatcactct agaatttgat gcatttttcg taacccaagt ttacactcca aacgctggtg
    10861 acggtctcaa acgcttggaa gaacgccaag tctgggatgc caaatatgct gagtatttgg
    10921 ctgaactaga caaagaaaaa ccagtccttg cgaccggtga ctacaacgta gcccacaatg
    10981 aaatcgacct tgcaaatcct gctagcaacc gccgttcacc tggatttact gacgaggaac
    11041 gtgctggatt taccaacctt ttggcaactg gatttacaga caccttccgc catgttcatg
    11101 gcgatgttcc tgaacgctac acttggtggg cacaacgcag caaaacttct aaaatcaaca
    11161 atacaggctg gagaatcgac tactggctca caagtaaccg tatcgctgac aaggtcacta
    11221 aatctgatat gattgactca ggtgctcgcc aagaccatac accgattgtc ttggaaattg
    11281 atttgtaagg attttctata tggactacaa tgcggtcatt cccgagttgc ttgtatcgaa
    11341 tatcgaacag tcccggtcct tctactgtgg tttactgggt tttaggattg aataccaacg
    11401 tccagaagaa aactttctct ttctcttgaa gagtgtcaac taatgttaga ggagggaaca
    11461 aaggatcaac tagctgaact gacctatcca tttggtcgtg gagtcaatct ctcctttggc
    11521 ataaaggatg tttcaaaact ctatcaaaga gtgatgaagg caaactatcc tatttatcgt
    11581 cccttgacca aaagaaagtt tcgtgtcagt gatccctata tctatcctca tgaatttgca
    11641 gttttggatc cagatggcta ttttttaaga tttagcgagt agaataataa aaattgggaa
    11701 aagtctttaa agttagaaaa aggcatattg tcaggtgttt aaaaacttga tagtatgcct
    11761 tttatgatgg aaaaatcttc taatactctt cgaaaatctc ttcaagccac atcaacgtca
    11821 ccttaccata ggtatatgat actgactctg tcaattctat ccacaacctc aaaacagtgt
    11881 tttgaggttg tggatagctt cctagtttgc tctttgattt tcatttagta taaatgttag
    11941 cttacaatgg agtttttgtt caccccctct tctgtttgtt cgttttttaa atcaaaacac
    12001 taacaaaata gttgatttat aaagttattt agtgtaaaat aaaaacattg gctcaagcct
    12061 atttaaaatt gaatatcgtt ttacttgttt atgtcgtgaa ttggcacgac gtttctacaa
    12121 ggtgccggaa cacctaacaa taagtaagtc agcagtgaga tatggccgtt tttgccatgc
    12181 ctatttgggg gacttactta gagattaagt aggtcttttt tgaatatttt taatatttcc
    12241 cttaattagt gcggacggga ggtgaaatta tcctgtgaat aatttcagga atccagggaa
    12301 tttcatccct aatttttgag cccctagctc tttcatttct aggcttaggc taaaatagtt
    12361 ccccgaacta ttttactctc aaaaatcccg tcatagacaa taacaagatt attgtctatg
    12421 ataccactac aacgggaaat atttgataag actcgcttcg ctcgtaatag ttttatcaaa
    12481 tatatagtat tagcaaaagg gatcactata gaaatattta aacaacaagt aaattaactt
    12541 ttagacttta ggaggtctta tgaaattatt agaagagcgc atcctcaagg atgggcatat
    12601 cttgggtgat aacatcctca aggtagattc ctttttaacc caccaagttg actttagctt
    12661 gatgcgagag attggtaggg tttttgcgga aaaatttgct gctactggca ttaccaaggt
    12721 cgtaaccatt gaagcgtcgg gtattgcccc agccgttttt acagctgaag ccttaaacgt
    12781 tcccatgatt ttcgccaaaa aagctaagaa catcaccatg aacgaaggca tcttaactgc
    12841 tcaagtctac tcctttacca aacaggtgac cagcaccgtt tctatcgctg gaaaattcct
    12901 ctcaccagag gacaaggttt tgattatcga cgatttcctt gctaatggcc aagctgctaa
    12961 aggcttgatt caaatcatcg aacaggccgg tgccacagtc caagctatcg gtatcgtgat
    13021 tgagaaatcc ttccaagatg gccgtgattt gcttgaaaaa gcaggctacc ctgtcctatc
    13081 acttgctcgt ttggatcgtt ttgaaaatgg tcaggtcgta tttaaggagg cagatctcta
    13141 atgcaaactc aagaaaaaca ctcgcaagca gccgttcttg gcttgcagca cttactagcc
    13201 atgtactcag gatctatcct ggttcccatc atgattgcga cagcccttgg ctattcagct
    13261 gagcagttga cctacctgat ttctacagat atcttcatgt gtggggtggc aaccttcctc
    13321 caactccaac tcaacaaata ctttgggatt ggactcccag tcgttcttgg agttgcattc
    13381 cagtcggtcg ctcccttgat tatgattggg caaagccatg gtagtggcgc tatgtttggt
    13441 gcccttatcg catctgggat ttacgtggtt cttgtttcag gcatcttctc aaaagtagcc
    13501 aatctcttcc catctatcgt aacaggatct gttattacca cgattggttt aaccttgatc
    13561 cctgtcgcta ttggaaatat gggaaataac gttccagagc caactggtca aagtctcttg
    13621 cttgcagcta ttactgttct gattatcctc ttgatcaaca tctttaccaa aggatttatc
    13681 aagtctatct ctattttgat tggtctggtt gttggaactg ccattgctgc tactatgggc
    13741 ttggtggact tctctcctgt tgcggtagct ccacttgtcc atgtcccaac tccactctac
    13801 tttgggatgc caacctttga aatctcatct attgtcatga tgtgtattat cgcaacggtg
    13861 tctatggttg agtcaactgg tgtttatcta gccttgtctg atatcacaaa agatccaatc
    13921 gacagcacgc gccttcgcaa cggttaccgc gcagaaggtt tggccgtact tctcggagga
    13981 atctttaaca ccttccctta caccggattt tcacaaaacg ttggtttggt taaattgtca
    14041 ggcatcaaaa aacgcctgcc aatctactac gcagctggtt tcctggttct ccttggactg
    14101 cttcctaagt ttggtgccct tgcccaaatc attccaagct ccgtcctcgg cggtgccatg
    14161 ctggtgatgt ttggttttgt atctattcaa gggatgcaaa tcctcgcccg agttgacttt
    14221 gctaacaatg aacacaactt ccttatcgca gctgtttcaa tcgctgcagg tgtcggtctc
    14281 aacaacagta atctctttgt cagcatgccg acagccttcc aaatgttctt ctcaaacgga
    14341 atcgtcgtag ccagcctact cgccattgtc ctcaatgccg tattaaatca taaaaagaaa
    14401 taagaaaaag aggtgcgatc ctcttttttg tttatcacaa attgattata aatacaatca
    14461 atcccaattc ccatctaatt gaattggacc tatttcaaat tctttaaaat attatgttcc
    14521 aaatcgttaa tattatataa gaatggtaaa atatcaaatg tttctcgtaa attattctta
    14581 gccttatacc aaccttgtcc atcagtaatc cacataaact caacattagg aatagcttta
    14641 atttcttcag caatcatttt gtaagatcta gccgtctcat ttaattttga accacttcct
    14701 gaataaaaat taacctcaat cagataaagc acttgttcat tttttatgac aaaatcaaaa
    14761 cgtttcacag tattcccatc attcgtaata gcagataaat cgacagaaaa aatttcctct
    14821 atttcatttt gttcaatctc tttaaataaa ttctctccta aaatataccc ttcagcttca
    14881 agatagcttt gaacaatatt ttccatcgca tctccagtcc gatttttgcg cccattagta
    14941 tccataccaa cctcaacacc tgtaacgtag tcaactaaat ttgatactaa atgattttgc
    15001 aataaatcaa atatacctga tttttccaaa aacatagtat attcttcaat actatagttt
    15061 cgtttactaa aatcaaaata gaaatctttt atcggatcct taacaataat cgtatctctc
    15121 aaacgtttag caataagtag aggcacaact ttcaaaattt ctggataatt ttgatataag
    15181 tctaaaaaat cctcttgtat atttttacta ccaataagac tattcataat atttagagca
    15241 acttttatac tagatacatt tttataaacc ttaggaaaat ctgtataata agtccagtca
    15301 gctactgtgt cggtcatcgt tgacaaccac tcatcaaaat ttctagtttg tttcattttc
    15361 tgcctccaac ctcttccttg caatttttaa atattctttt tcagcatcga tacctataaa
    15421 tcttctacct aaccgcttcg caacaacacc cgtagtgcca ctaccaacaa atgggtctag
    15481 aatatagtca ccctctttag tagaggctaa aataatgcgt tctaacaaat actctggttt
    15541 ttgagttgga tgtttcccag cccatttttc aactttcttt gttaaagaac cggtccagac
    15601 atctttcatt tgttttccat cattcaattc tttcattaaa tcataattgt agtaatgacg
    15661 agctttttta tcattttttc tggcccataa aatggtttca gtagaatggg taaaataacg
    15721 acaagataaa ttgggggcag ggtttgtttt ctgccaagta atattattca gaattttaaa
    15781 accttcttgt tctaatgcca ttccaactga gtatatgttg tgcaaactac ctgaaatcca
    15841 taccgtccca ttaggcttca gaacttcttt tgctaggcga atccatttac gattaaactc
    15901 atgtttttct tcgaatgaag aaattttatc ccaatctcct ttatcaacag aaacaacttg
    15961 tcccccagaa ttagatattc caccattact taaaaaataa ggtggatcag caaaaatcat
    16021 atccatactt tctggtttca tttttgataa gaacttgaac gtatctgaat gaacaagaat
    16081 catcttattt ttattgtagt atggttttgt cataagaaca cctccatact tatattcgtt
    16141 atttttcata atttgtgact ataatttcag aaatttttcc tcgacttgaa gattttgctc
    16201 cattagttcg ggtagcttca acataatgta tattaaaatc cttatacaac tcctctacta
    16261 aagcactaga agaatttgat aacataacat aagctcctgt atcactcaat ctcttaaagg
    16321 catctcttaa tcttacttga tctgcaaaag agaatccctc atgagtataa gacgtaaatg
    16381 cactcgtctc agacaatgga atatatggag ggtcaaaata cacaaaatct cctgttcgaa
    16441 catctacaat tgccttttca aaatctccca ctttaatttc tagttgattg ttatttatat
    16501 aaactgaaat agcagatatc aattcctcat caacaatttt aggattctta taacgtccat
    16561 atggaacatt aaattgattc ttagaattca cacgatatag accattaaag ttcactctca
    16621 acatatatag aatacgtgca gctctttgta cttcggacat catatctatt ctttcatcac
    16681 gatctgcaga acgtaaatct aaataatatt cttttgaatt atattcctga tgaactttca
    16741 aaatttcaat caattcttga ggattgtcct taatttgttg atagcaattt attagttcag
    16801 cgttaaaatc attaataact gcatctttag gagccaaatc aaaaaataaa gctccacctc
    16861 caacaaaagg ttcgaaatac ctgttatagg ttttaggcat taattctcta ataacaggca
    16921 ataattgtct tttaccacct gtccatttcg tgaacggttg taaagtaact ttctttattt
    16981 cttttatctt catgctttta attataccat agaaattaaa acacaactct tgtattttct
    17041 accacattac taaattttct attttagaat taaatcatat caatatcaaa aaatgagtaa
    17101 ggcaaatctt ataaattcca aaattcacct cactctatta aattactctt tatatcctta
    17161 cctgtctttc ttctgaccgc tggcctgtga caaacatggt aaaggttgct ttacagacat
    17221 ttctgccctc ttgattggtg atatccacat ccatcacaca ggttgtacga ccttgatgga
    17281 cacattctcc tttaatggtc aatacatcgt cgagttttcc tgccttaagg tagttgatag
    17341 aggattggag tgtcacccca tcaagtccca gcgagataac caccaaacca ctgatttggt
    17401 cacatagcgt gaatagatag ccaccatggg cattgccata gtagttgagc gacgagttca
    17461 ctactttggt cgtcaccaca acgtgaccat ctctcatttt ttcaatttcg taattttcaa
    17521 aggcagatat agcgtcaaaa tgaaagtctt tcatcgtttc ctcctgatat ttcaaacgac
    17581 actatgatac tactttttat aggactgtgc aaggagaaag ctcctagtct agtaaaattc
    17641 cgacctgttc cacaaagcgc ataaaggctg tctgaccttg ttctgtctgc ttgtagactc
    17701 ctgcatcctc aagtacacgc acaaagatag cacccacaga gtccttgacg attgcaaggg
    17761 ctttttcttt atccgttagg tctggatgtt gggatttgag ttggtctgcc cactcctgat
    17821 gataatcggc aactgtaaca gcttctccta caagatagct agcgacttgc tccacttctt
    17881 ctttcagacg tggtggcaag attgccaagc ccatgacctc aatcaagccg atattttcct
    17941 tcttgatatg ttggacatcc ttgtggggat gatagatgcc atcaggatgc tctgctgaag
    18001 tctgattgtc tcgcaagacc aagtccaact caaactgtcc atcacgctta cgcgctattg
    18061 gtgtgatggt gtgatgcggt gtcccgtctg tctctgctaa aatctgcaca ctagaatctg
    18121 aatactgacg ccattcctgg aaaatcttat cagctaagtt aatcaaatcc tctttggaat
    18181 ccgaagtcaa gcgtaggaca gacattggcc acttgataat tccagccttg acctgctcaa
    18241 aaccagcaaa tcggaaggtc ttttgcaagg gagccaattc cataggaaat acgtgacggc
    18301 ctccctgata atgatcatga gttagaatag agccccccac aatcggcagg tcggcattag
    18361 atccagcaaa atatcctgga aactgctcta cgatagccaa cagacgttca aaactctgac
    18421 gactaatggc catgggacga tgctggccat ctaaaaagat acaatgctca ttaaagtaag
    18481 catagggcga atactggaac ccccattcct gaccaaccat ttcaaaacgg ataatccggt
    18541 ggttgctgcg agctgggtgg ttgacccgac catggtaacc ctcattctct aaacaaagtt
    18601 gacactgagg ataattacta gcttgcacca acttggctac cgcaatctct ttcggatcct
    18661 tttcaggctt agagagattg atggtaattt caagttctcc ataatcagat ggaacacgat
    18721 aagcgatatt tttagcaatg gccttgagtt tgatgtagtc atttttccga ctgagttgat
    18781 aaaaatcctc tatcgcttgc tcaggagagt aggcataggc ttcccagaag tcacgattga
    18841 cctgactcgg acaaggagtc accaagtcca tcagttcagt accaaggatt tcacgcgcag
    18901 tctgactatc ctcaatcgtc tctaatcgaa cggcttcctc aactagctgg tccttgaggt
    18961 caatcaattt atccagattg gtctcaactt ccaaaacacc ttctcccact cgtgccaaaa
    19021 cacgattggt caggtagatt cgatccattt cctcaaatga actttcagaa atgacatgtg
    19081 ttacaaattt atctactaag gtcactatag agcctccttt tgactagtca aggacgcgag
    19141 tgccacctgc aacttcagcg atatagaagc ttggagcgta tccaactact tcctcgtagt
    19201 gtttgcctac agcttcctta aagacctcaa cagtatcttt ttgaaccaag gcaatggcac
    19261 agccaccaaa accagcccct gtcatacgag caccgagaac tccttcttgt gcccaagctg
    19321 tgtgaacaag ggtatctaat tccaaaccag ttacttcata atcatgctcc agagaaacgt
    19381 gtgacgcatt catcaaacga ccaaatgttt ccaaatcacc tgcttgaagg gctgcttgag
    19441 ctttaagggt gcgttggttt tcaagcacag catggcgagc acgtttcaaa cgattttcat
    19501 ctttaatcag atagctatat tggtcaaagg cccactcgtc caattcaccc aaggtctgaa
    19561 tatccaaggc aacttgcaac tcttccactg ctttttcaca ctcagcacga cgttcattgt
    19621 atttagagtc cgccaattca cggcgtttgt tggtgttcat gataacaacg acattgtcct
    19681 tcaaatcaag tggcaccaaa tcatactcta aggtgttggt atcaaggtaa atagcacgtt
    19741 gatcagcccc cataccaata gcaaactggt ccatgatacc agagttgact ccgataaagt
    19801 tgttttctgt ttgttttccg attttaacca aatcgagacg ctctaatttt aaatcaaaga
    19861 gatgctctgc cacgactcct gtcaagagct ccaaggatgc tgaagaagac aaaccagcac
    19921 catttggtat attcccataa acataaaaat caaaaccttt gtcaatcacg tgcccagctt
    19981 cttgcaagaa atgaaggaca ccttttggat aattggtcca gttgtgctct ttttcaaact
    20041 tgaggtcagc gagaggcact tcgataatgc ccttgtcctc aaagttagct gagtagaaac
    20101 gcaaaacttg gtcgtcacgc ttacgagctg caccgtaagt tcccaaggaa atagcagcag
    20161 gaaaaacgtg cccaccgttg tagtctgtgt gttcaccaat caaattgata cgacctggtg
    20221 aaaagaaagt ttggtctgct tcttgaccaa aaacagcaag aaagtctttg cgaagagttt
    20281 cagcagtaag atgttgtgtc atatgatttc tcctttgact gtccgttaag ccaccttaac
    20341 gtgtaatcgt tttcttctat tgtatccaag ggatttccca aggtcaatcc tttttactaa
    20401 aattttacta aaatatcagt aaaaagcaga aaaatatgat atactaacct aatcaaggag
    20461 gatttatggc taccttaaaa gacattgcac agctagcctc tgtctctatc gcgaccgtat
    20521 cccgtgtcct caaccgcgac cagagcctat ctgttacaga agaaaccaga caccgtattt
    20581 taaccgttgc tgaagagctg ggctacacca agcacctcaa gacaggcgag tcccataaac
    20641 ccaagcaaaa gattgccatt atccaatggg tcagcgaaca aggggagctg gacgacctct
    20701 actactacca gattcgccta ggaatagaaa aaagagccca agagttggac tatgatatct
    20761 tgcgctattt taatgaccat ccttttacct taagcgagga agtgattggg attctctgca
    20821 ttggaaaatt tagccgagct cagatttctg cctttgaaga ataccaaaaa cccctggtct
    20881 ttctagacag tgatacactt tccctgggac atacctgtat tatcacggat ttttacactg
    20941 ctatgaaaca ggttgtcgat tatttcctca gccaaggaat ggaccgtatc gggattctaa
    21001 caggccttga agaaacgact gaccaagaag aaatcattca ggataagcgg ctggaaaatt
    21061 tcagaaacta cagtcaagca aaaggaatct atcatgatga actggtcttt caaggaaact
    21121 ttactgccca gtctggctat gacttgatga aggaagccat tcagagcttg ggagaccaac
    21181 tcccaccagc atttttcgca gccagcgata gtttagccat cggtgccctt cgtgcgctcc
    21241 aagaagctgg aatcagccta ccagaccgtg tcagcctcat ttcctttaac gacaccagcc
    21301 tgaccaagca ggtttatcct cccctctcca gcatcacagt ttatactgaa gaaatggggc
    21361 gagcaggtat ggatattctt aacaaggaag tcctccacgg tcgcaaaatt cctagcctga
    21421 ccatgctggg aaccagactg acattaagag aaagtaccct aaatcaagaa taggataaca
    21481 taaaaaacga atagagttct aaaactccta ttcgtttttt attcgattac aatcatagac
    21541 ttaattgtct tacgttcatc catatcttta taggcttggt cgatatcttc cagtttataa
    21601 cttgaagtaa agacgcgacc tggattgata tcaccatcaa ggacggcttt tagtaaaaat
    21661 tgcttatcgt atgttgtagc agaagctgcc ccacctgcta cagagatatt ttgcataaat
    21721 gtcgaaccaa gagcacgatt attatagtgt gggactccta caaagcccat acgccctcca
    21781 ttatgaagaa cacctagcgc ctgttctata gcagcctccg taccaacaca ttcaagtgct
    21841 gcatctgctc ctccaccgag gatttcacgc accttggtaa ttccttcttg accacgttct
    21901 gcaacaacag ctgtcgcacc tgactccata gccatctttt gacggtcttc atgacggctc
    21961 ataaggataa tttgtgatgc tccacgcatc ttagccgcga tgacagcaca ttgaccaaca
    22021 gccccatcac cgataacaac aaccttgtcc cctttttgaa catttgcaac acgcgccgca
    22081 tgatagcctg tcggcatgac atctgcaaga gtcaaaaggg acttgagcat cccttctgta
    22141 tagtcagaag gttgaccagg gattttaacc agcgcccagt ttgcatagtg gaagcgaata
    22201 tattctgcct gaaaatcacc ccccaaatta ttgccaatat gattgtcgca agaaccgtca
    22261 aatccagcaa gacaggcatc acactcacca catccatgtg taaaagggac aatcacaaaa
    22321 tcacctggtt tcaccgtcgt aatggcttcc ccagcttctt caacaatccc aatcgcttcg
    22381 tgtccactat ttttgtgtcc agctttcgtt tctggattac ggtacctcca taaatctgaa
    22441 ccacaaacgc acgcacgaac cacacgaata atcacatcat ccgcttctat tatttgcgga
    22501 cgttcaatgc tagcaagtcc aacctgacct gcctttgtat atactgctga tttcatttaa
    22561 aattttcctt ccttataaag tttaattttg agatttaaac gatttaaagc tgtctgtagc
    22621 tgagacaagc gctcctctaa tttttgcttt tcctcttcta aaataccaag cctctcctct
    22681 ctcgtttcat ctcccttttg gtagagcgac atatagtcaa ctaaactatc tacagagaca
    22741 cccgccgaac gaaaacactt aataaattcc agcgcttcga tatcctgatc ttgaaaatca
    22801 cgaatcccag tagcagtacg agtaatcggt ggcacaagac caacccgttc ataataccga
    22861 atcgtatccg ctgaaattcc caacaaatca ctggcagatt taatattcac acgctaacct
    22921 cctctcattt cattcactga attcacgcta ttctaactca cttatcttat tatataactt
    22981 tgagttgact ccaagtcaag cattttgtat ctaatcgaaa aatttttatc attaacaatc
    23041 atatatctgg agtttataca atgctcttct cttaccaatt tttgaaatat ttaaataata
    23101 aagaaattac tctattccaa ataagatagt acccaagtat ttttcacttt tttctaatgt
    23161 tgatgctcat aactccgttc caagtcacac acctttcgct tatgggtttg gtgagtttct
    23221 aggtcagcat caatttcaat ggtaatattt tgaaaaccac aatcttttag gaaaattcga
    23281 atagactctt tacaagtttc catatgttcc atttctttta gacaaacatg gacaatggca
    23341 tttttttcca aagcatccat agtccagaga ttaagctgat taaggctggc cacattgtcc
    23401 aatcgttcca ggccactctt tacttgcttg atatcaagac cttctggcac agcatccaag
    23461 aaaatcttga gtgtagacca aaaacgtgaa agggcttttg aaagaataaa gaaagaaatg
    23521 acaagggaca aaagaggatc taggatatac cagtccgtaa atcgaagaac aatcgccatc
    23581 aggataacag ctacccaccc tagcgtatct tccagaaaat gcagactcag aatagactca
    23641 ttctttgtct ttcccttacc aaccaccaga ctcgctaaca gattgatagt aatcgcaata
    23701 attcctaacc agagaatccc ctcatcattg actggttgcg gatgcaaaat cttcgtgaca
    23761 ttttccaaaa tgactagaac agagcctgtt acgagaatca cagctgttac caaggctcct
    23821 agcaggctaa accgcttata gcccaaggtg tactgattgt cttcttcacg attggagatt
    23881 gtttctagaa aagctgatat tccaattgca atcacatctc ccaagtcatg cacagagtca
    23941 gcaagaacag cgctagaacc aaatactcca cctgcaataa actcaacaat ggcataagtc
    24001 aaatttaaga aaaaagccac ccaaacagca tattttgcct tcatatttct cattcctttg
    24061 ttataatagg tttatgaaca ccttgttcat tatcattatc cactaaaact caaagaaagg
    24121 atagaagcaa aacgtcagct ttattcagtt ctgaacaatt tgccttaagt gtccatatga
    24181 ctaacattga ccgccgtatc agcaaaacca aaaaagccat ctatcaagct tttatacaac
    24241 ttttgaatgc taagggctac gaggccacta ctgttcagga tatcattgat ctcgcagatg
    24301 tgggaagatc caccttttac tgtcactatg aaagtaagga gcttcttctg gaccagctct
    24361 gccgctacct cttccatcat ctttttgaaa gagagcaagc catttcaacc gaggactacc
    24421 tcgcccacct ctttctccat tttcataaaa accaagacca tatcaccagt ctgctatttt
    24481 ccaaaaatga ctacttcctc cgtcaactcc ataaagagct agaacaccat gtctattccg
    24541 tgctagctga taatttaaaa gaagcccacc ctaatatgcc tacttcttac ctccaacact
    24601 tggtcgtgtc caactttatc gagacattga cctggtggct caaaaaaggt caagatttca
    24661 cagaccagga agttgtccaa ttttatctag accttctcat tcctaaaaat tgaatataga
    24721 gtaaagctca gttgtcttat ttctaggtta ctgagttttt tatcttttca acaacaaaag
    24781 aggacccgcc gatcctcttt ttcatactat aaatccttga ttatcaacta tatctgtttt
    24841 aatcgaaatc tcaaaacagc actttcaaac atcttttcct agttaggtaa atcagtattc
    24901 tgcttagctg ccttgctcca ttgataccaa ccaactagac tgttaatgag ataaattaga
    24961 tatttccctt gaatttgcag gctttctccc caccagagat agattgaaaa aacattggta
    25021 gccgcccaga atatccactg ttcacggtaa acagctgtca tgaggatttg ccctacccca
    25081 ttggttgcat ctgtgattga atcacgatag ggacgattgg caccaataga ctgataaatg
    25141 aagccaaagg ccaaccacca aagcacacta atggaaagat actttgtcca gcccttgccg
    25201 tccagtttac gcgcgacaaa ctcctgcttt tccttcttaa actgtgcctg ataaatccaa
    25261 actagaagtc caattggctg catgactgtg aagtaaagtg tcgtcagcac ctcaccataa
    25321 aagcctttct gtagggccaa aataaggtaa ataacagagt taatcaagcc aaaaagataa
    25381 ttacttgctc gaccttccga tacaaagatt acacagataa tccctgtcaa gctacaaatc
    25441 atcccaatcc agtcaacaat acgatgttcg taaaccaact ccagccagag aggaaaactt
    25501 cctaaaacca gcaaataaat ccactgggca aaactacgat gggcaaagag gtcatcccag
    25561 atagccttca tagttcctga aaatcctaaa tcagccatag ccgcaaccat acgacggtaa
    25621 ccacctgaca tttcacctag ggttgttttg atattttcaa ttttcttttg caaataagta
    25681 tgcatcattt ctccttttgt ttttaaagag ccgtgtctgg atagactttc ggacgcaacg
    25741 ctctattaga taatgaactg cctatacaca agatttctaa ccttagtcga catgagctga
    25801 aacctcttat ttgttaagta gttcacaaaa tattatacac ctattttatg aatagtcaac
    25861 tgtctttaca gtaaaatttt agaaaatcat gaaaattttc tctttctttc cattttaagt
    25921 gacattcagt cattctcaca tcaaaaaagc ccagacgaaa ctgtctgagc attcttttat
    25981 ctagtcgttt aaggaagttg agttcagtat gttt
//
LOCUS       DAVBOD010000022        25267 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 640-05
            SAMEA1012484-rid20186543.denovo.022, whole genome shotgun sequence.
ACCESSION   DAVBOD010000022 DAVBOD010000000
VERSION     DAVBOD010000022.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012484
            Sequence Read Archive: ERR059358
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 25267)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25267)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979948.1
            Genome Coverage       :: 595x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:03:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,266
            CDSs (total)                      :: 2,219
            Genes (coding)                    :: 2,091
            CDSs (with protein)               :: 2,091
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 71 of 128
            Pseudo Genes (incomplete)         :: 50 of 128
            Pseudo Genes (internal stop)      :: 33 of 128
            Pseudo Genes (multiple problems)  :: 22 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25267
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012484-rid20186543.denovo.022"
                     /strain="NIG 640-05"
                     /db_xref="taxon:1313"
     gene            complement(112..387)
                     /locus_tag="VQ862_001059"
     CDS             complement(112..387)
                     /locus_tag="VQ862_001059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002950996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HU family DNA-binding protein"
                     /protein_id="HET3115420.1"
                     /translation="MANKQDLIAKVAEATELTKKDSAAAVEAVFAAVADYLAAGEKVQ
                     LIGFGNFEVRERAERKGRNPQTGKEMTIAASKVPAFKAGKALKDAVK"
     gene            complement(494..1333)
                     /locus_tag="VQ862_001060"
     CDS             complement(494..1333)
                     /locus_tag="VQ862_001060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000161411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HET3115421.1"
                     /translation="MTKIKIVTDSSVTIEPELVKQLDITIVPLSVMIDNVVYSDADLK
                     EEGKFLQLMQESKNLPKTSQPPVGVFAEIFEDLCKDGGQILAIHMSHALSGTVEAARQ
                     GASLSTADVTVVDSSFTDQALKFQVVEAAKLAQEGKDMEAILCHVEEVKNHTELYIGV
                     STLENLVKGGRISRVTGLLSSLLNIRVVMQMKDHELQPMVKGRGTKTFKKWLDELITS
                     LSERAVAEIGISYSGSDDWAKEMKESLQAYVEKPISVLETGSIIQTHTGENAWAILIR
                     YHS"
     gene            1475..2323
                     /locus_tag="VQ862_001061"
     CDS             1475..2323
                     /locus_tag="VQ862_001061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000592058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HET3115422.1"
                     /translation="MIKKIYPIFTILLGAAIYAFGLTYFVVPHHLFEGGATGITLITF
                     YLFKIPVSLMNLLINIPLFILAWKIFGAKSLYSSLLGTLALSGWLAFFEHIPLHIDLQ
                     GDLLITALIAGILLGIGLGIIFNAGGTTGGTDILARILNKYTHISIGKLLFILDFCIL
                     MLILLIFKDLRLVSYTLLFDFIVSRVIDLIGEGGYAGKGFMIITKRPDQLAKAINDDL
                     GRGVTFISGQGYYSKENLKIIYCIVGRNEIVKTKEMIHRIDPQAFITITEAHEILGEG
                     FTFEKE"
     gene            complement(2416..3333)
                     /locus_tag="VQ862_001062"
     CDS             complement(2416..3333)
                     /locus_tag="VQ862_001062"
                     /EC_number="2.7.1.26"
                     /EC_number="2.7.7.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000587449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional riboflavin kinase/FAD synthetase"
                     /protein_id="HET3115423.1"
                     /translation="MIITIPIKNQKDIGTPSDSVVVLGYFDGIHKGHQELFRVANKAA
                     RKDLLPIVVMTFNESPKIALEPYHPDLFLHILNPAERERKLKREGVEELYLLDFSSQF
                     ASLTAQEFFATYIKAMNAKIIVAGFDYTFGSDKKTAEDLKDYFDGEVIIVPPVEDEKG
                     KISSTRIRQAILDGNVKEAGKLLGAPLPSRGMVVHGNARGRIIGYPTANLVLLDRTYM
                     PADGVYVVDVEIQRQKYRAMASVGKNVTFDGEEARFEVNIFDFNQDIYGETVMVYWLD
                     RIRDMTKFDSVDQLVDQLKADEEVTRNWS"
     gene            3770..3975
                     /locus_tag="VQ862_001063"
                     /pseudo
     CDS             3770..3975
                     /locus_tag="VQ862_001063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844775.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
     gene            complement(4286..4579)
                     /gene="rpmA"
                     /locus_tag="VQ862_001064"
     CDS             complement(4286..4579)
                     /gene="rpmA"
                     /locus_tag="VQ862_001064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L27"
                     /protein_id="HET3115424.1"
                     /translation="MLKMTLNNLQLFAHKKGGGSTSNGRDSQAKRLGAKAADGQTVTG
                     GSILYRQRGTHIYPGVNVGRGGDDTLFAKVEGVVRFERKGRDKKQVSVYPIAK"
     gene            complement(4596..4940)
                     /locus_tag="VQ862_001065"
     CDS             complement(4596..4940)
                     /locus_tag="VQ862_001065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000613691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal-processing cysteine protease Prp"
                     /protein_id="HET3115425.1"
                     /translation="MIQAVFERAEDGELRGAEITGHAESGEYGLDVVCASVSTLAINF
                     INSIEKFAGYEPILELNEDEGGYLMVEIPKDLPSHQREMTQLFFESFFLGMANLSENY
                     SEFVQTRVITEN"
     gene            complement(4956..5270)
                     /gene="rplU"
                     /locus_tag="VQ862_001066"
     CDS             complement(4956..5270)
                     /gene="rplU"
                     /locus_tag="VQ862_001066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018374562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L21"
                     /protein_id="HET3115426.1"
                     /translation="MSTYAIIKTGGKQVKVEVGQAVYIEKLNVEAGQEVTFNEVVLVG
                     GENTVVGTPLVAGATVVGTVEKQGKQKKVVTYKYKPKKGSHRKQGHRQPYTKVVINAI
                     NA"
     misc_feature    complement(5306..5393)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00559"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L21 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00559"
     gene            complement(5488..6087)
                     /locus_tag="VQ862_001067"
     CDS             complement(5488..6087)
                     /locus_tag="VQ862_001067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001858962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1275 domain-containing protein"
                     /protein_id="HET3115427.1"
                     /translation="MTFCAGYVDAYTFIVRGNTLVAGQAGNVVFLSVELIQNNVSDVR
                     DKLLTLITFIMGVFLLTIYKEKLRIVKKPILSLIPLAILSIIIGFVPQTVDNIYLVQP
                     LAFCMGLVTTAFGEVSGIAYNNAFMTGNIKRTMLAFGDYFRTKHTPFLREGFIFVSLF
                     SSFVLGVVFSAYLTIFYHEKTILGVPIMMSIFYLSMLFA"
     gene            6557..6856
                     /locus_tag="VQ862_001068"
     CDS             6557..6856
                     /locus_tag="VQ862_001068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaB/EbfC family nucleoid-associated protein"
                     /protein_id="HET3115428.1"
                     /translation="MMNMQNMMRQAQKLQKQMEQSQAELAAMQFVGKSAQDLVQATLT
                     GDKKVVSIDFNPAVVDPEDLETLSDMTVQAINSALEQIDETTKKKLGAFAGKLPF"
     gene            7075..8152
                     /locus_tag="VQ862_001069"
                     /pseudo
     CDS             7075..8152
                     /locus_tag="VQ862_001069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014632353.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(8468..9442)
                     /gene="pta"
                     /locus_tag="VQ862_001070"
     CDS             complement(8468..9442)
                     /gene="pta"
                     /locus_tag="VQ862_001070"
                     /EC_number="2.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acetyltransferase"
                     /protein_id="HET3115429.1"
                     /translation="MEVFESLKANLVGKNARIVLPEGEEPRILQATKRLVKETEVIPV
                     LLGNPEKIKIYLEIEGIMDGYEVIDPQHYPQFEEMVSALVERRKGKMTEEDVRKVLVE
                     DVNYFGVMLVYLGLVDGMVSGAIHSTASTVRPALQIIKTRPNVTRTSGAFLMVRGTER
                     YLFGDCAININPDAEALAEIAINSAITAKMFGIEPKIAMLSYSTKGSGFGESVDKVVE
                     ATKIAHDLRPDLEIDGELQFDAAFVPETAALKAPGSTVAGQANVFIFPGIEAGNIGYK
                     MAERLGGFAAVGPVLQGLNKPVNDLSRGCNADDVYKLTLITAAQAVHQ"
     gene            complement(9486..10382)
                     /locus_tag="VQ862_001071"
     CDS             complement(9486..10382)
                     /locus_tag="VQ862_001071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001209987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HET3115430.1"
                     /translation="MRFEFIADEHVKVKTFLKKHEVSKGLLAKIKFRGGAILVNNQPQ
                     NATYLLDVGDYVTIYIPAEEGFETLEAIEHPLDILYEDDHFLVLNKPYGVASIPSVNH
                     SNTIANFIKGYYVKQNYENQQVHIVTRLDRDTSGLMLFAKHGYAHARLDKQLQKKSIE
                     KRYFALVKGDGHLEPEGEIIAPIARDEDSIITRRVAKGGKYAHTSYKIVASYGNIHLV
                     YIHLHTGRTHQIRVHFSHIGFPLLGDDLYGGSLEDGIQRQALHCHYLSFYHPFLEQDL
                     QLESPLPDDFSNLITQLSTNTL"
     gene            complement(10379..11197)
                     /locus_tag="VQ862_001072"
     CDS             complement(10379..11197)
                     /locus_tag="VQ862_001072"
                     /EC_number="2.7.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000799053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD kinase"
                     /protein_id="HET3115431.1"
                     /translation="MKNTGKRIDLIANRKPQSQRVLYELRDRLKRNQFILNDTNPDIV
                     ISIGGDGMLLSAFHKYENQLDKVRFIGLHTGHLGFYTDYRDFELDKLVTNLQLDTGAR
                     VSYPVLNVKVFLENGEVKIFRALNEASIRRSDRTMVADIVINGVPFERFRGDGLTVST
                     PTGSTAYNKSLGGAVLHPTIEALQLTEIASLNNRVYRTLGSSIIVPKKDKIELIPTRN
                     DYHTISVDNSVYSFRNIERIEYQIDHHKIHFVATPSHTSFWNRVKDAFIGEVDE"
     gene            complement(11181..11852)
                     /locus_tag="VQ862_001073"
     CDS             complement(11181..11852)
                     /locus_tag="VQ862_001073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000171686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase family protein"
                     /protein_id="HET3115432.1"
                     /translation="MTLEWEEFLDPYIQAVGELKIKLRGIRKQYRKQNKHSPIEFVTG
                     RVKPIESIKEKMARRGITYATLEHDLQDIAGLRVMVQFVDDVKEVVDILHKRQDMRII
                     QERDYITHRKASGYRSYHVVVEYTVDTINGAKTILAEIQIRTLAMNFWATIEHSLNYK
                     YQGDFPDEIKKRLEITARIAHQLDEEMGEIRDDIQEAQALFDPLSRKLNDGVGNSDDT
                     DEEYR"
     gene            11980..12549
                     /locus_tag="VQ862_001074"
     CDS             11980..12549
                     /locus_tag="VQ862_001074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000681289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CYTH domain-containing protein"
                     /protein_id="HET3115433.1"
                     /translation="MKHLEIELKTLLKKDEYNRLKDQFTGVTPVLQTNYYIDTPDFEL
                     REKKVAMRIRTFEDWAELTLKVPQSVGNMEYNQKLQLKDAEDYLSKEELPQGLVLDEL
                     AKHGIQSKNWQVLGCLTTLRYEMKTAIGLMALDQSRYFDITDYELELEVENHEQGKQD
                     FRQFLEKNQISYQKAPSKLVRFVKSMKNS"
     gene            12662..13621
                     /locus_tag="VQ862_001075"
     CDS             12662..13621
                     /locus_tag="VQ862_001075"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HET3115434.1"
                     /translation="MSDRKNMKLFALNSNQEIAQKIAQAVGVPLGKLSSRQFSDGEIQ
                     VNIEESVRGYDVYIIQSTSFPVNNHLMELLIMVDACVRASAHSINVVLPYFGYARQDR
                     IACPREPLTAKLVANMLVKAGVDRILTLDLHAVQVQGFFDIPVDNLFTVPLFAKHYCD
                     KGLLGSDVVVVSPKNSGVKRARSLAEYLDAPIAIIDYPQDDATRNEGYIIGDVEGKKA
                     ILIDDILNTGRTFSEASKIVEREGATEIYAVSSHGLFVEGAAELLDNTNIKEILVTDS
                     VATKEKTPKNVCYITASELIGDAIVRIHERKPVSPLFAYNKKK"
     gene            13631..14746
                     /locus_tag="VQ862_001076"
     CDS             13631..14746
                     /locus_tag="VQ862_001076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HET3115435.1"
                     /translation="MIYLDNAATTPMSAVAISAMTKVMQETHGNPSSIHGHGRQAGKL
                     LREARQELAQLLRTKPQHIFFTSGGTEGNNTTIIGYCLRHQEQGKHIITTAIEHHAVL
                     ETIDYLVQHFGFEATIIQPENQEITAQQIQKALRDDTILVSTMFTNNETGNLLPIAEI
                     GQILKQHPAAYHVDAVQAIGKIPIHSEELGIDFLTASAHKFHGPKGIGFLYASSMDFD
                     SYLHGGDQEQKKRAGTENLPAIVGMVAALKEDLEKQEEHFQHVQNLETAFLAELEGIQ
                     YYLNRGKHHLPYVLNIGFPGQKNDLLLLRLDLAGISISTGSACTAGVVQSSHVLEAMY
                     GANSERLKESLRISLSPQNTVEDLQTLAKTLKEIIGG"
     gene            14751..15098
                     /locus_tag="VQ862_001077"
     CDS             14751..15098
                     /locus_tag="VQ862_001077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1831 domain-containing protein"
                     /protein_id="HET3115436.1"
                     /translation="MAFEKIIQLKNCRYDYTLGPSVKKFTLKDNTFFETKVGNYELTR
                     LLEKVPNSGEGFQLKIIINKEVTGAKINITDKFGLRLVDIFKSEDHHIHQEKFYFLMD
                     SLVERGVFTKSER"
     gene            15106..15321
                     /locus_tag="VQ862_001078"
     CDS             15106..15321
                     /locus_tag="VQ862_001078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000462494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4649 family protein"
                     /protein_id="HET3115437.1"
                     /translation="MFELTYKDCYHVERTLKYEDHEALMLTLSGCVTLPDTLYVTSLT
                     FRGQKVYQGLVGDLYRFLSHADFLHQN"
     gene            15404..16045
                     /locus_tag="VQ862_001079"
     CDS             15404..16045
                     /locus_tag="VQ862_001079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000653420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HET3115438.1"
                     /translation="MKDKQFAIPKATAKRLSLYYRIFKRFHAEKIERANSKQIAEAIG
                     IDSATVRRDFSYFGELGRRGFGYDVKKLMTFFADLLNDNSITNVMLVGIGNMGHALLH
                     YRFHERNKMKIIMAFDLDDHPEVGTQTPDGIPIYGISQIKDKIKDADVKTAILTVPSV
                     KSQEVANLLVDAGVKGILSFSPVHLHLPKDVVVQYVDLTSELQTLLYFMRKED"
     gene            16063..16752
                     /locus_tag="VQ862_001080"
     CDS             16063..16752
                     /locus_tag="VQ862_001080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HET3115439.1"
                     /translation="MKKPVIGITGNEKTHPDDDIMMSYAAKGFVEGVKDAGGIPIILP
                     IGDQEMACHYISLIDKLILTGGQNVDPKFYGEPKTIDSDDYHLQRDIFELALIKEAIK
                     QKKPIFSVCRGTQLFNVAMGGTLYQDIEDHWQDSSVEYTTQRLVTEPDTVLQEIYGEI
                     SHINSFHHQSIKDLAPNLKVVAHDPKDGIIEAVMSTDDVAFLGVQWHPELLFENRPKD
                     KKLFDYVVNEL"
     gene            complement(16749..17429)
                     /gene="radC"
                     /locus_tag="VQ862_001081"
     CDS             complement(16749..17429)
                     /gene="radC"
                     /locus_tag="VQ862_001081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000286923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadC"
                     /protein_id="HET3115440.1"
                     /translation="MYSISFQEDSLLPRERLAKEGVEALSNQELLAILLRTGTRQASV
                     FEIAQKVLNNLSSLTDLKKMTLQELQSLSGIGRVKAIELQAMIELGHRIHKHETLEME
                     SILSSQKLAKKMQQELGDKKQEHLVALYLNTQNQIIHQQTIFIGSVTRSIAEPREILH
                     YAIKHMATSLILVHNHPSGAVAPSQNDDHVTKLVKEACELMGIVLLDHLIVSHSNYFS
                     YREKTDLI"
     gene            complement(17472..19763)
                     /gene="pcrA"
                     /locus_tag="VQ862_001082"
     CDS             complement(17472..19763)
                     /gene="pcrA"
                     /locus_tag="VQ862_001082"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000992850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase PcrA"
                     /protein_id="HET3115441.1"
                     /translation="MNALLNGMNDRQAEAVQTTEGPLLIMAGAGSGKTRVLTHRIAYL
                     IDEKLVNPWNILAITFTNKAAREMKERAYSLNPATQNCLIATFHSMCVRILRRDADHI
                     GYNRNFTIVDPGEQRTLMKRILKQLNLDPKKWNERTILGTISNAKNDLIDDVAYAAQA
                     GDMYTQIVAQCYTAYQKELRQSESVDFDDLIMLTLRLFDQNPDVLTYYQQKFQYIHVD
                     EYQDTNHAQYQLVKLLASRFKNICVVGDADQSIYGWRGADMQNILDFEKDYPKAKVVL
                     LEENYRSTKTILQAANEVIKNNKNRRPKNLWTQNADGEQIVYYRADDELDEAVFVART
                     IDELSRSQNFLHKDFAVLYRTNAQSRTIEEALLKSNIPYTMVGGTKFYSRKEIRDIIA
                     YLNLIANLSDNISFERIINEPKRGIGPGTVEKIRDFANLQNMSMLDASANIMLSGIKG
                     KAAQSIWDFANMMLDLREQLDHLSITELVESVLEKTGYVDILNAQATLESKARVENIE
                     EFLSVTKNFDDTTDVTEEETGLDKLSRFLNDLALIADTDSGSQETSEVTLMTLHAAKG
                     LEFPVVFLIGMEENVFPLSRATEDTDELEEERRLAYVGITRAEKILYLTNANSRLLFG
                     RTNYNRPTRFINEISSDLLEYQGLARPANTSFKASYSSGSISFGQGMSLAQALQDRKR
                     GAAPKSIQSSGLPFGQFTAGAKSASSEANWSIGDIALHKKWGEGTVLEVSGSGARQEL
                     KINFPEVGLKKLLASVAPIEKKI"
     gene            complement(19954..20759)
                     /locus_tag="VQ862_001083"
     CDS             complement(join(19954..20382,20385..20759))
                     /locus_tag="VQ862_001083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS5 family transposase"
                     /protein_id="HET3115442.1"
                     /translation="MNDEASKQLTDARFKRLVDVQRTTFEEMLAVLKTAYQLKHAKGG
                     RKPKLSLEDLLMATLQYVREYRTYEQIAADLGIHESNLIRRSQWVEVTLVQSGFTISR
                     TPLSSEDTVMIDATEVKTNRPKKQLANYSGKKKFHAMKAQAIVTSQGRIVSLDITVNY
                     CHDMKLFKMSRRNIGQAGKILADSGYQGLMKIYPQAQTPRKSSKLKPLTVEDKAYNHA
                     LSKERSKVENIFAKVKTFKMFSTTYRNHRKRFGLRMNFIAGIINHELGF"
     gene            complement(21139..21999)
                     /locus_tag="VQ862_001084"
     CDS             complement(21139..21999)
                     /locus_tag="VQ862_001084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013903404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl aminopeptidase"
                     /protein_id="HET3115443.1"
                     /translation="MITLKSAREIEAMDKAGDFLASIHIGLRDLIKPGVDMWEVEEYV
                     RRRCKEENFLPLQIGVDGAMMDYPYATCCSLNDEVAHAFPRHYILKDGDLLKVDMVLG
                     GPIAKSDLNVSKLNFNNVEQMKKYTQSYSGGLADSCWAYAVGTPSEEVKNLMDVTKEA
                     MYKGIEQAVVGNRIGDIGAAIQEYAESRGYGVVRDLVGHGVGPTMHEEPMVPNYGIAG
                     RGLRLREGMVLTIEPMINTGDWEIDTDMKTGWAHKTIDGGLSCQYEHQFVITKDGPVI
                     LTSQGEEGTY"
     gene            complement(22015..23292)
                     /locus_tag="VQ862_001085"
     CDS             complement(22015..23292)
                     /locus_tag="VQ862_001085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HET3115444.1"
                     /translation="MSKHQEILSYLEELPVGKRVSVRSISNHLGVSDGTAYRAIKEAE
                     NRGIVETRPRSGTIRVKSQKVAIERLTFAEIAEVTSSEVLAGQEGLEREFSKFSIGAM
                     TEQNILSYLHDGGLLIVGDRTRIQLLALENENAVLVTGGFQVHDDVLKLANQKGIPVL
                     RSKHDTFTVATMINKALSNVQIKTDILTVEKLYRPSHEYGFLRETDTVKDYLDLVRKN
                     RSSRFPVINQHQVVVGVVTMRDAGDKSPSTTIDKVMSRSLFLVGLSTNIANVSQRMIA
                     EDFEMVPVVRSNQTLLGVVTRRDVMEKMSRSQVSALPTFSEQIGQKLSYHHDEVVITV
                     EPFMLEKNGVLANGVLAEILTHMTQDLVVNSGRNLIIEQMLIYFLQAVQIDDILRIQA
                     RIIHHTRRSAIIDYDIYHGHQIVSKANVTVKIN"
     gene            complement(23285..23836)
                     /locus_tag="VQ862_001086"
     CDS             complement(23285..23836)
                     /locus_tag="VQ862_001086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET3115445.1"
                     /translation="MNIWTKLAMFSFFETDRLYLRPFFFSDSQDFREIASNPENLQFI
                     FPTQASLEESQYALANYFMKSPLGVWAICDQKNQQMIGSIKFEKLDEIKKEAELGYFL
                     RKDAWSQGFMTEVVRKICQLSFEEFGLKQLSIITHLENEASQRVALKSGFSLFRQFKG
                     SDRYTRKMRDYLEFRYVKGEFNE"
     gene            complement(23852..25111)
                     /locus_tag="VQ862_001087"
     CDS             complement(23852..25111)
                     /locus_tag="VQ862_001087"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HET3115446.1"
                     /translation="MRKIVINGGLPLQGEITISGAKNSVVALIPAIILADDVVTLDCV
                     PDISDVASLVEIMELMGATVKRYDDVLEIDPRGVQNIPMPYGKINSLRASYYFYGSLL
                     GRFGEATVGLPGGCDLGPRPIDLHLKAFEAMGATASYEGDNMKLSAKDTGLHGASIYM
                     DTVSVGATINTMIAAVKANGRTIIENAAREPEIIDVATLLNNMGAHIRGAGTNIIIID
                     GVERLHGTRHQVIPDRIEAGTYISLAAAVGKGIRINNVLYEHLEGFIAKLEEMGVRMT
                     VSEDSIFVEEQSNLKAINIKTAPYPGFATDLQQPLTPLLLRANGRGTIVDTIYEKRVN
                     HVFELAKMDADISTTNGHILYTGGRDLRGASVKATDLRAGAALVIAGLMAEGKTEITN
                     IEFILRGYSDIIEKLRNLGADIRLVED"
BASE COUNT         7793 a         5396 c         4472 g         7606 t
ORIGIN      
        1 aatattttcg gaacattcaa ctttttaact ctatttatta ctagatttca taattaaaaa
       61 gcctactgac caagctagaa agcttgatac aataggcttt ttaaagactg attatttaac
      121 agcgtcttta agagctttac cagctttgaa tgctggtact ttagaagctg caattgtcat
      181 ttctttacca gtttgtgggt tgcgaccttt acgttctgcg cgctcacgaa cttcaaagtt
      241 accaaaaccg atcaactgaa ctttttcacc agctgcaaga tagtcagcta ctgctgcaaa
      301 tacagcttca actgctgctg ctgagtcttt cttagtcaat tctgtagctt ctgctacttt
      361 agcgatcaaa tcttgtttgt ttgccatgtt aatgattcct ccaaataatt tctaattaac
      421 aaatataatc atatcctaaa atccctttta ggtcaagtta aaaacgctat ttcttcccat
      481 tttatttatt tttttaggag tggtaacgta tcaaaatagc ccaagcgttc tcacccgtgt
      541 gagtttgaat aatggaaccc gtttccaaaa cagaaattgg cttttcaaca taagcttgta
      601 agctttcttt catctctttt gcccaatcat cactaccaga atatgaaatt ccaatctctg
      661 ctacagcacg ttcagaaagc gatgttatca actcatctaa ccatttttta aatgttttag
      721 ttccacgacc tttaaccatt ggctgcaatt catggtcttt catttgcatg acaacacgga
      781 tattgagaag agagctcaac aagccagtta cacggctaat tcgtccacct ttgacaagat
      841 tttccaaagt tgaaacacca atataaagct ctgtatggtt tttaacctct tctacatgac
      901 ataaaattgc ctccatatct ttaccttctt gagctaactt cgcagcctca acaacttgga
      961 atttcagggc ttggtcagtg aaggaactat caacaacagt cacatctgca gtagataggc
     1021 tagcaccttg gcgtgctgct tctaccgtac ccgaaagagc atgggacata tgaatagcaa
     1081 gaatctggcc accatctttg cataggtctt caaaaatctc agcaaagaca cctacaggtg
     1141 gctgacttgt tttcggaaga ttcttacttt cttgcatcaa ctgaagaaat ttaccttctt
     1201 ctttcaaatc cgcatcagaa taaacaacat tatcaatcat tacagataat ggaacaattg
     1261 taatatctaa ttgctttact agttcaggtt caatagtaac agatgaatcg gttacaatct
     1321 taatttttgt catagtatca atctttctat tttaggattc agattggttt ccttacttct
     1381 aattatatca aaaaaaagat taaaaatcct aatggagtca atcaaatttt ccgtaaaatt
     1441 tgatataatc aacttataag aaaagaggtg tcctatgatt aaaaaaattt accccatttt
     1501 taccatttta ctaggtgctg ctatttatgc ttttggactg acttattttg tagttcccca
     1561 tcatctcttt gaaggagggg cgacaggtat taccctcatc acattttatc tttttaaaat
     1621 ccctgtttcc ctcatgaacc tgctgattaa tattcccctt ttcatcctag cttggaaaat
     1681 ctttggagcc aaatccctct attctagttt actaggaacc ttagctttgt ccggctggtt
     1741 agcttttttt gagcatattc cccttcatat tgatcttcaa ggtgatttac taatcacagc
     1801 ccttatagcg ggaatcctat tgggaattgg ccttggaatt atttttaatg ctggaggtac
     1861 aactggtgga actgatattc tagctcgtat tctcaacaaa tacactcata tatccatagg
     1921 aaaactgctc tttatcttag atttttgtat tctcatgttg attctcctaa tcttcaagga
     1981 tttgagattg gtttcctaca cgcttttgtt tgattttatt gtttctcgtg ttattgattt
     2041 gattggtgaa ggaggatatg ccggcaaagg ctttatgatt atcacaaaac gtcctgacca
     2101 acttgctaag gcgattaatg atgacctcgg aagaggtgtt acttttattt ctggtcaagg
     2161 ctactatagt aaagaaaatt tgaaaatcat ctactgtatt gtcggaagaa atgaaattgt
     2221 gaaaacgaag gaaatgattc atcgaatcga tcctcaagcc tttataacta ttacagaagc
     2281 ccatgaaatc ctaggagaag gcttcacctt tgaaaaagaa taaaaagagg taatgtcgtg
     2341 acctcaaaag ttagactaaa tcatctatct tttgggttac agacaacctc ttttttgttt
     2401 tatttactca agctcttaag accaattccg agttacttct tcatcagcct ttaactgatc
     2461 cactaattgg tcaactgagt caaatttggt catatcacga atgcgatcaa gccaataaac
     2521 catgacggtt tccccataaa tatcttgatt aaaatcaaaa atattgactt caaaacgtgc
     2581 ttcttctcca tcaaaggtca catttttccc gacactagcc atagcacgat acttctgtct
     2641 ttgaatctca acatcaacga cataaacgcc atctgctggc atataagtac ggtctaaaag
     2701 cactaaattc gctgtcggat aaccaattat acgaccacga gcattaccat gaaccaccat
     2761 acctcttgat ggaagcggtg cccccaaaag ttttcctgct tctttcacat ttccatctaa
     2821 aatagcttga cggatacgag ttgaactaat ctttcctttc tcatcttcta caggtggaac
     2881 aatgataact tctccatcaa agtaatcctt taaatcttct gctgtttttt tgtcagaacc
     2941 aaatgtataa tcaaaacctg caacaataat tttggcattc atagccttga tataagttgc
     3001 aaagaattct tgtgcagtga gactagcgaa ttgactacta aaatcaagga gatataattc
     3061 ttctacacct tcgcgcttta attttctttc acgttcagca gggttcaaaa tatgcaaaaa
     3121 caaatccgga tgataaggct ctaaagcgat ctttggagat tcattaaagg tcataacgac
     3181 gataggtaat aaatcctttc tcgcagcctt gttggcaaca cgaaataatt cttgatgccc
     3241 cttatgtatg ccatcaaaat agccgagaac aacgactgaa tcagatggtg tgccaatatc
     3301 tttttggttt tttataggaa tagtaataat cataaaataa ttatatcata gcgatagcta
     3361 tttctggaac agaaaatctg aaatgttgtt tttttcacat gaagtgtacc tgttttcaaa
     3421 aagcacttta ttctatcgtt gcttaactat gaactttgca atattcttct caaaaacttg
     3481 taggacatct tcaaaatttt gcaaggagtg attagacttg ttcggtaacc ataaagtgtc
     3541 atactatgtt atgtatgaaa aagcaatgca actaactcct gagaacttta aattactaat
     3601 tggtgccgaa aaggtagaat ttagaatcga ggtacaccta tggctgtaaa atttacaaaa
     3661 tgagacaact tgggcaagat gtttgaagaa tttcctaaac tccctgattt gaagcaagtc
     3721 actttccctg atgacaaaga aaaaagccaa aacagcaaag aaaaactaga tgactgcttt
     3781 ccaacaactc ccatctagtg tgcttcagac tgggctattt ttctctccat ctgttagctt
     3841 ggattctcag accgtttcag ctaaagaata tcttttccct tatcagaagg aacggctcaa
     3901 accattcaga caagtgaagg gacgacaagc caatatttga aaccagatag cagttcttat
     3961 agtcaattga aataaaatct gaagaaatcg agtaggaaac tcatatcaat ttttaacagt
     4021 gttctattcc agattcatac tcaatgaaaa ttaaagtgca aactaggaag ttagccgcag
     4081 gctgtacttg agtacggcaa ggtgaaactg acgtggtttg aatttgattt tcgaagagta
     4141 tcaatccact atacatatta aaaagtatgg atatcaaaac aaaaaaacag gctctccgaa
     4201 aactcggaaa gccttatttt aagctgtttc tagcttcctc acctttacat ttcaaggttc
     4261 gggataaaag gttcaatgga cctttttatt tagcgattgg gtaaacagaa acttgttttt
     4321 tatcgcgtcc tttacgttca aagcgtacta cgccttcaac tttagcgaac aaagtatcgt
     4381 ctccaccacg accaacgttt acacctggat agatgtgtgt accacgttga cggtaaagga
     4441 ttgatccacc tgttacagtt tgtccgtcag ctgctttagc tccaagacgt tttgcttgtg
     4501 aatcacgtcc gtttgatgta gaacctccac cttttttgtg ggcgaaaagt tgcaagttgt
     4561 taagagtcat ttttaacata atgttttcct ccgtgttagt tttctgtgat aactctggtt
     4621 tggacgaact cagaatagtt ctccgataag tttgccatac ctaagaaaaa tgattcaaag
     4681 aataactggg tcatttctct ctggtgtgaa ggaagatctt ttggtatttc aaccatcaga
     4741 tagccacctt catcttcgtt taattctagg attggttcat agcctgcaaa tttctcaata
     4801 gaattgataa agttaatggc aagcgtagaa accgatgcac acacgacatc taagccgtat
     4861 tcgccactct cggcgtgtcc agtaatttcc gcacccctca gctcgccatc ttcggctctc
     4921 tcaaagactg cttgtatcat gtgttctcct taaaattaag cgttaattgc gttgatgaca
     4981 acttttgtat atggttgacg gtgaccttgt ttacggtggc tacctttttt aggtttgtac
     5041 ttgtaagtaa caactttctt ttgttttcct tgtttttcaa cagttccaac tacagtagct
     5101 ccagcaacaa gtggagttcc gacaacagtg ttttcaccac caacaagaac aacttcgtta
     5161 aaagtaactt cttgaccagc ttcaacgttc aatttttcaa tgtaaactgc ttgaccaact
     5221 tcaactttaa cttgttttcc gccagttttg ataattgcgt atgtgctcat tatgcacctc
     5281 ctatgatttt tatgggtttc cccgattttt tgtgaagact cgcctagcat cgtgggacaa
     5341 accacttaaa cttgaataat caagcaacga tgttcgtgcg gttgcacagg atcgtgcata
     5401 gtcaactctt caagtatagc atatctccta ttttcttaca agtaataaca cctaaaatca
     5461 agctttttct tttacttttt tctgccacta ggcaaaaagc atactgagat aaaaaatgct
     5521 catcataata ggaacaccaa gaatggtctt ttcatgatag aaaatcgtca aataggctga
     5581 aaagacaacg ccaaggacaa aactactaaa caggctaaca aatatgaacc cttcacgcaa
     5641 aaaaggagtg tgcttagttc ggaaataatc tccaaaagct agcattgttc gtttgatatt
     5701 ccctgtcata aaggcattat tgtaggcaat acccgaaacc tcaccaaaag cagttgtcac
     5761 cagtcccata cagaaggcca agggctgcac tagatagata ttatctacag tttgtggcac
     5821 aaaaccaata attattgata ggattgctaa aggaatcaag gacagaatag gttttttcac
     5881 aattctcaat ttttccttat aaatcgttaa taaaaagact cccattataa acgttattaa
     5941 ggttaaaagc ttatccctaa catccgaaac attattttgt attagctcta ccgaaagaaa
     6001 gacaacattt ccagcttgtc cagctacaag ggtattccct cgaacaataa aagtgtaagc
     6061 atccacatat ccagcacaaa atgtcaaaaa agtgctaacc ttttagactg acgtgatatt
     6121 tttcttatag gtaataacct cattttccct cccattgtat tttctcttag aaatattgta
     6181 ccatttcttt ctaaaaaatc gtagactacc atttagattt tactattagc ataaaaataa
     6241 taatagacaa ctatttatcc aaaaatagat agaggtaaca tgtttgcaaa caaagcatac
     6301 gaacctttag taaaatcatt tccatgaaac tagaatagag cccctcttag caaaaatcat
     6361 tattttaatt tatttctaat cactccttga cataaataac tctcaccaat aaaagactat
     6421 gtcttaaaaa aatggtataa taaaatcaat acctgggctt gatggctatg ctactaataa
     6481 caattaggag agaaaatcag gcacttgtta acaacaagga ttatcccctt gagatgaaag
     6541 gaactttaga aatcttatga tgaacatgca aaacatgatg cgtcaagcac aaaaacttca
     6601 aaaacaaatg gaacaaagcc aagctgaact tgctgctatg caatttgttg gcaaatctgc
     6661 tcaagatctt gtccaagcga ccttaactgg cgataagaaa gttgtcagca ttgatttcaa
     6721 tccagctgtc gttgacccag aggaccttga gactctttct gatatgaccg ttcaagccat
     6781 caactctgct cttgaacaaa tcgatgaaac tactaagaaa aaactgggtg ctttcgctgg
     6841 gaaattgcca ttctaaaaac aaggagctag aacaatactt gtcgataaca aaggctaaga
     6901 aaggtgcaaa aattataaaa aacgcatagt atcaagcaac ctaaaacttt gggctctata
     6961 atatttgtag tgggtaaatc cactatagat attatggagc ctattttatt gtagaaaaaa
     7021 atcccataag atctataatg aaaagcgacc aaacaactca ttagaaagat tcatatggga
     7081 caattacatt ttatcacaaa attactagac attaaagacc ctaatatcca gattttagac
     7141 atcatcaata aggatacaca caaggaaatc atcgccaaac tggactacga cgccccatct
     7201 tgccctgagt gcggaagtca aatgaagaaa tatgactttc aaaaaccgtc taagattcct
     7261 taccttgaga caactggtat gcctactaga atcctcctta gaaagcgtcg attcaagtgc
     7321 tatcactgtt caaaaatgat ggtcgctgaa acttctatcg tcaagaagaa tcaccaaatc
     7381 cctcgtatca tcaaccaaaa gattgctcaa aagttaattg aaaagatttc tatgactgat
     7441 attgcccatc agctttccat ctcaacttca actgttattc gtaagctcaa tgattttcac
     7501 tttgagcatg atttttcgcg tcttcctgag attatgtctt gggacgttga aacagtccgg
     7561 ggagtgactg tttcaatcgg gagatggaga tgagctttat tgctcaggac tttgataagc
     7621 tcaatatcat aactgttctt gagagcagaa cacaagccat catccgaaat cccatgaata
     7681 caaggctatc aagcgctact ggaaactcat tcaacaggat agccgtaaac tgagtgataa
     7741 gcgattttat cgtcctactt ttcgtatgca tttaaccaat aaagagattt tagacaagct
     7801 tttgagctat tcacaagact tgaaacatca ctatcagctc tatcaactct tgctgtttca
     7861 ctttcagaat aaggaaccgg agaaattttt cggactcatt gaggacaatc taaagcaggt
     7921 tcatcctctt tttcagactg tctttaaaac ctttctaaag gacaaagaga aaatcgtcaa
     7981 cgcccttcaa ctaccctatt caaacgccaa attggaagcg accaataatc tcatcaaact
     8041 tatcaagcgc aatgcctttg gttttcggaa ctttgaaaac ttcaaaaaac ggatttttac
     8101 cgctctgaat atcaaaaaag aaaggacaaa atttgtcctt tctcgagctt agcttttctt
     8161 caacccacta cagttgacaa agagccagaa aacgcataat agcaggtgtc aagacactta
     8221 atattatgcg ttttctcatg aaaaaattct cttttcatac tcatttaaaa tcaaaaaggg
     8281 aaattatcgt tttacggaca tacatattac agatttctat aggtcgtgta tagacaggat
     8341 atcatcgctt ggaagttttc ctttttgaca ccaatcagta atttagttct caggaattaa
     8401 tggcagtgct tttcgtacat agtttcataa ctacagtata gcatagtata tcgctttata
     8461 gttttcacta ttgatgaact gcttgagctg ctgtgatgag ggtcaacttg taaacatcat
     8521 ctgcattaca tccacgagaa agatcattaa ctggcttgtt taaaccttgc aaaacaggtc
     8581 ctacagccgc aaagccaccc aggcgttcag ccatcttgta accgatattt ccggcctcga
     8641 tacctgggaa gatgaagaca tttgcttgac cagctaccgt acttccagga gctttcagag
     8701 ctgcagtttc aggaacaaag gctgcatcaa attgcaactc accatcgatt tcaaggtcag
     8761 gacgcaagtc gtgagcaatt ttagttgctt caacgacctt atcaacgctt tcaccaaacc
     8821 ctgaaccttt agtagaatag ctcaacatgg caattttagg ttcgatgcca aacatcttag
     8881 ctgtgattgc tgagttgatg gcaatttcag ccaaggcttc tgcatctgga ttgatgttaa
     8941 tggcacagtc tccaaatagg taacgttccg taccacgaac catgaggaag gctcctgaag
     9001 tacgagttac atttggacga gttttgatga tttgtagagc tggacgaact gttgaagctg
     9061 ttgagtgaat cgctcctgac accattccat caaccaagcc caagtaaacc aacatcacac
     9121 caaagtagtt gacatcttca accaaaacct tgcgtacatc ttcttcagtc attttgccct
     9181 tgcgacgctc caccaaggca gaaaccattt cttcaaattg aggataatgt tgagggtcga
     9241 tgacctcata accatccatg attccttcaa tttcaagata aattttaatt ttttcaggat
     9301 ttccaagcaa aacaggaatc acttctgttt cttttactaa gcgttttgtt gcttgaagaa
     9361 tacgaggctc ttccccttca gggagaacga tacgagcatt tttaccaaca aggttggctt
     9421 tgagactttc aaaaacttcc atgagttttc tcctttaaga taataattat actctgagac
     9481 agtttttata gagtattagt tgataactgg gtaataaggt tactgaaatc atccggcaag
     9541 ggactttcta actgcaagtc ttgctctaaa aatggatgat aaaaggatag gtaatggcaa
     9601 tgcagagcct gacgttgaat accatcttcc agactaccac catacaaatc atctcccagc
     9661 aaaggaaaac cgatatgaga aaaatggact cggatttgat gggttcgacc agtgtgcagg
     9721 tgaatataga ccaagtgaat atttccataa gaagctacaa tcttgtatga agtatgggca
     9781 tactttccgc ctttagccac tcgtctggta ataatggaat cttcatcacg cgcaatcgga
     9841 gcaataattt ccccttctgg ctccaaatgt ccatctccct taaccaaagc aaagtagcgt
     9901 ttctcgatag atttcttctg caactgcttg tctaatcgtg catgggcata accgtgcttg
     9961 gcaaagagca tcaagccaga agtgtcccta tctagtctgg taacaatgtg aacctgctga
    10021 ttttcataat tttgcttgac atagtaaccc ttgataaaat tggcaatggt gttagagtga
    10081 ttgacactag gaatagaagc cactccatag ggtttattca agactagaaa gtggtcatcc
    10141 tcatagagaa tatctaatgg atgctcaata gcctccaagg tttcaaagcc ttcctcagcg
    10201 ggaatgtaaa tggtaacgta gtctccaacg tccaatagat acgttgcatt ttgcggttga
    10261 ttattgacca gaatagctcc acctcgaaac ttaatcttag ccagcaatcc cttagaaacc
    10321 tcgtgctttt ttaaaaaggt cttaaccttg acatgttcat ctgcgataaa ttcaaacctc
    10381 attcatccac ctcaccgata aaggcatcct taacacggtt ccagaaactg gtatggctag
    10441 gagtcgcgac aaagtgaatc ttatgatggt cgatttgata ctcaatacgc tcaatattac
    10501 ggaaagaata aacgctattg tcaaccgaaa tagtatgata atcgtttctt gttggaataa
    10561 gttcaatctt atccttctta ggcacaataa tggaagagcc cagtgttcga taaacacgat
    10621 tattaaggct ggcaatttcc gttaattgca aagcttcaat ggtagggtgt aaaacagcac
    10681 cgccaagaga cttgttatag gcagtactac cagtcggtgt cgaaactgtt agcccgtctc
    10741 cacgaaaacg ttcaaaggga acaccattta ttacaatatc tgccaccatg gttcgatcag
    10801 acctgcggat gctggcttcg ttgagtgctc tgaaaatctt aacttcacca ttttcaagaa
    10861 agaccttcac attcagaaca gggtaagaaa cccttgcccc agtatctagc tgcaaattag
    10921 tcactagctt gtccaactca aaatcacgat aatctgtata gaagcccaaa tgtccagtat
    10981 gaagaccgat aaagcggacc ttgtcaagct gattttcgta cttatgaaag gccgacaaga
    11041 gcataccatc cccgccaatg gaaatgacaa tatccggatt ggtatcattg agtataaact
    11101 gatttctctt caaacgatct cgcaattcat acaaaaccct ttgactctgc ggttttctat
    11161 tggctatcag atcaattcgt ttacctgtat tcttcatctg tatcgtcact gtttcctaca
    11221 ccgtcattta attttctact caaaggatca aaaagtgcct gggcttcttg gatatcatca
    11281 cgaatttcac ccatttcttc atccaactga tgggcgattc tagctgtaat ttccagtcgc
    11341 ttcttaatct catctgggaa atccccttgg tacttgtagt tgagagaatg ttctatcgtt
    11401 gcccagaaat tcatggccaa agtacgaatt tgaatttctg ccaaaatagt cttagctcca
    11461 ttgatggtat caaccgtata ttctactacc acatgatagg aacgatagcc tgatgctttt
    11521 ctatgagtaa tgtaatctcg ctcctgtatg attcgcatat cctgacgctt gtgcaaaata
    11581 tccactactt ccttgacgtc atctacaaac tgaaccatca cacgtaagcc agcaatatcc
    11641 tgcaaatcgt gttccaaggt cgcataagta atgccacgac gagccatttt ttctttgatg
    11701 ctctcaattg gcttgactcg accggtcaca aactcaattg gagaatgctt attttgctta
    11761 cgatattgct tacgaatacc acgaagttta atctttaact caccaacagc ttgaatgtaa
    11821 ggatctagaa attcttccca ttctaaggtc atatattctc ccttgttctc atattatccg
    11881 tcaaaaatat ctttgatttt ttctccagat tcatatacaa taaatacaat gcttattata
    11941 ccataaatcc gctttcaacg ataaaaaaag gtaagaaaaa tgaaacattt agaaattgaa
    12001 ttgaaaacac tattgaaaaa agatgaatac aatcgtctaa aagaccagtt cacaggtgtc
    12061 actcctgttc ttcaaacaaa ttactacatc gacacgcctg attttgaact gcgagaaaag
    12121 aaagtcgcta tgcgcattcg aacctttgaa gactgggctg agttgacact caaagtcccg
    12181 cagagtgttg gaaacatgga atacaaccaa aaattgcaac taaaagatgc tgaggactat
    12241 ctgagtaagg aagaacttcc tcaaggacta gtactggatg aattggcgaa acatggtatc
    12301 caaagtaaga actggcaggt tcttggttgt ctaacaacgc ttcgctatga aatgaaaaca
    12361 gctattggtc tcatggcact ggatcagagc cgatactttg atataacaga ttacgaattg
    12421 gagcttgaag tggaaaatca tgagcaaggc aaacaggatt tccgacaatt tttagagaaa
    12481 aatcagattt cctaccaaaa agctccttca aaattggttc gatttgtcaa aagtatgaaa
    12541 aatagctgaa ataatctcca ttttttggta aaatagaaaa gataaaaata cacaaatccc
    12601 agttcatata tgtaaggtaa atataactag gatttataaa gtttacagag gacggtctat
    12661 aatgtcagat agaaaaaaca tgaaactttt cgcactcaac tctaaccaag agattgcaca
    12721 aaaaattgcc caagctgttg gtgtcccact tggaaaacta tcatcacgtc aattttcaga
    12781 cggagaaatc caagtaaata tcgaagaaag tgtccgtggt tatgatgttt acatcatcca
    12841 atcaacaagt ttccctgtca acaaccacct aatggaattg ttaatcatgg tcgatgcttg
    12901 tgtgcgtgca agtgcccaca gtatcaacgt tgtccttcca tattttggct atgcacgtca
    12961 agaccgcatt gcttgtcctc gtgagccact tacagcaaaa ctagttgcca atatgctggt
    13021 taaggctgga gttgatcgta tcctgactct tgatttgcat gccgttcagg ttcaaggttt
    13081 ctttgatatt ccagtggata atcttttcac tgttccccta ttcgcaaaac attactgcga
    13141 taaaggattg cttggttcag atgttgttgt cgttagccct aaaaattcag gtgtcaaacg
    13201 tgcgcgtagc ctggctgaat atcttgatgc tcctatcgcc attatcgact accctcaaga
    13261 cgatgcaact cgtaacgaag gttatattat tggtgatgtt gaaggtaaga aagctatctt
    13321 gattgatgat attttaaata caggacgtac cttctctgaa gcttctaaaa tcgttgaacg
    13381 tgaaggagct acagaaattt atgctgtttc tagccacggt ctcttcgtcg agggagctgc
    13441 tgagcttctt gacaatacta atattaaaga aattcttgtg actgattcag tagcaacaaa
    13501 agaaaaaact cctaaaaatg tatgctatat cactgctagt gagttaattg gtgatgctat
    13561 cgtacgtatt cacgaaagaa aaccagtcag cccactcttt gcctacaata aaaagaaata
    13621 aggtgattct ttgatttatt tggacaatgc tgcaacgact cctatgtcag cagttgctat
    13681 ttcagctatg accaaggtta tgcaagaaac ccacggaaat ccttctagta ttcatggtca
    13741 tggtcgtcaa gctggcaaac tcttgcgaga agcccgtcag gaactagccc agttactaag
    13801 gacaaaacct caacatatct ttttcacttc tggtgggact gaaggcaata atactaccat
    13861 cattggctac tgtcttcgtc accaagaaca aggaaaacat atcatcacaa ctgccatcga
    13921 gcaccatgct gtccttgaaa caattgatta cttggttcaa cactttgggt ttgaagcaac
    13981 cattatccag ccagaaaatc aagaaatcac agcccagcaa attcaaaagg ctttacgtga
    14041 cgatacgatt ttggtttcta ccatgtttac caataatgag acaggaaacc tactgcccat
    14101 cgctgaaatt ggccaaatac tcaagcaaca ccctgctgcc tatcatgttg atgcagttca
    14161 ggctattggt aaaatcccaa ttcattcaga agaattgggc attgattttc tcactgcttc
    14221 tgcccacaaa ttccatggtc ctaagggaat cggttttctc tacgcatcta gcatggactt
    14281 tgattcctat ctacatggcg gagaccagga acagaaaaaa cgtgcaggaa ctgaaaatct
    14341 gcctgctatc gtaggcatgg ttgcagccct aaaagaagac ctagaaaaac aagaagaaca
    14401 ttttcaacat gtacaaaatc tagaaactgc ctttctggca gagctggagg gcattcagta
    14461 ttacttgaat agaggaaaac atcatctccc ttatgttctc aatattggat ttcctggtca
    14521 gaaaaatgac ctcttactcc ttcggctaga tttagctgga atttcaatct ctactggctc
    14581 agcctgtact gcaggcgttg tccaatccag ccatgttctt gaagccatgt atggcgcaaa
    14641 ttcagaacgc ttgaaggaat cccttcgcat cagtttgtcg ccacaaaata ccgttgaaga
    14701 cctacaaacc ctcgcaaaaa ccttaaaaga aattatcgga ggttagccat atggcatttg
    14761 aaaaaatcat tcagttaaaa aattgtcgtt acgattacac tcttggccct tctgttaaaa
    14821 aattcaccct caaagataac accttttttg aaactaaggt tggtaactat gaactgactc
    14881 gccttttgga aaaagtgcca aacagcggtg aaggcttcca actcaaaatc atcattaaca
    14941 aggaagttac aggggctaaa atcaatatca ctgataagtt tggccttcgt ctagttgata
    15001 ttttcaaatc agaagaccac catattcatc aggaaaaatt ctacttcctc atggatagct
    15061 tggtagaacg tggtgtcttt acaaaatcgg aaagatagag ccaaaatgtt tgaactgacc
    15121 tataaggact gctatcatgt agagcgtact ctcaagtatg aggatcatga ggctctcatg
    15181 ttgactttgt caggatgtgt aaccttacca gatacacttt atgtgacttc tctgactttt
    15241 aggggccaaa aagtttatca gggtctggtc ggagacctct accgttttct atctcatgca
    15301 gattttttac atcaaaacta agatttttct tagttttttc ttatttttgt tgattttttc
    15361 acaatgtttc tataaaatag aagaatagaa aggttgtgat tttgtgaaag ataaacagtt
    15421 tgctattcca aaagctacag caaaaagact ctctctctac tatcgaattt ttaagagatt
    15481 tcatgcagaa aagattgaac gtgccaactc taagcaaatt gcagaggcta tcggtattga
    15541 ttcagcgacc gtacgtcgtg atttttccta ttttggtgaa cttggtcgtc gtggttttgg
    15601 atatgatgtc aaaaaactaa tgacattttt tgccgatttg ctcaatgaca actctattac
    15661 caatgtcatg ctggttggta ttggaaatat gggccatgcc cttctccact accgcttcca
    15721 cgaacgtaac aagatgaaga ttatcatggc ctttgaccta gatgaccatc ctgaagtcgg
    15781 tacccaaact cctgacggga ttcccattta cggaatttct cagatcaagg ataaaatcaa
    15841 ggatgctgat gtgaagactg ctatcctaac tgttcccagc gtcaagtcac aagaggttgc
    15901 taatctcttg gttgatgctg gtgtgaaagg aattctcagt ttttcaccag tccatctgca
    15961 tttaccaaaa gacgtggtcg ttcagtatgt cgatttgaca agtgaactcc aaaccctcct
    16021 ctacttcatg cgaaaagagg attagaaagc gaaaatcatt ttatgaaaaa accagttatt
    16081 gggattacag gaaacgaaaa aactcatcca gatgatgaca tcatgatgag ctacgcagca
    16141 aaaggctttg ttgaaggcgt taaagatgct ggagggattc ccatcatcct accgattggt
    16201 gatcaagaaa tggcctgcca ctatatcagt ttgattgaca agctcatctt gacaggtggg
    16261 caaaatgtcg atccaaaatt ctatggcgaa cccaaaacca ttgatagcga tgactatcac
    16321 cttcaaagag atatcttcga actggccctc atcaaggaag ctattaaaca gaaaaagccc
    16381 attttctctg tctgccgtgg tacccaactc tttaacgttg ccatgggtgg aactttgtac
    16441 caagatatcg aagaccattg gcaggattct tctgttgagt acacaactca acgcttggtg
    16501 acagaaccag ataccgttct ccaagaaatc tatggagaaa tctctcatat caactccttc
    16561 caccaccaga gcatcaagga cttagcacca aatttaaaag ttgtggctca tgatcctaaa
    16621 gatggtatca ttgaggctgt catgagtacg gatgatgtcg cctttctcgg tgtccaatgg
    16681 catccagaac ttctttttga aaatcgtccc aaagataaaa aactctttga ctatgtcgtt
    16741 aatgaacttt agattaaatc tgtcttttca cgataactaa agtaattaga atgagagaca
    16801 atcaaatggt ccaagagaac aatccccatc agttcgcagg cttctttaac aagtttagtg
    16861 acatgatcat cattttggct aggcgctacc gctcctgaag gatgattgtg gaccaagata
    16921 agagaagtcg ccatatgctt gattgcatag tgcagaatct ctcgcggttc agcgatacta
    16981 cgagttacag aaccgataaa aatggtctgc tgatggatga tttgattttg agtattgaga
    17041 tagagtgcca ccaggtgctc ttgtttttta tcccctaatt cctgctgcat cttcttggcc
    17101 aacttttgac tgctgagaat actttccatt tcaagagtct cgtgtttgtg aatacgatgc
    17161 cccagttcaa tcatagcttg taattctatg gccttaacac gcccaatacc agacaaactc
    17221 tgcaattcct gcagggtcat ttttttcaaa tccgttaggc ttgaaagatt gttcaagact
    17281 ttttgggcaa tttcaaaaac gctagcttga cgtgttcctg tcctgagtaa aatagctagc
    17341 aactcttggt tactaagcgc ttcaactcct tccttggcca gcctttctct tggtaatagt
    17401 gaatcttctt ggaatgaaat actgtacata aaaatcctcc tcactttatt attcgtgaga
    17461 aggatggaaa attagatttt tttctcaatt ggagccacac tggctaaaag ttttttcaaa
    17521 cctacttctg ggaaattgat tttcaattcc tgcctagcac cgctacctga aacttccaga
    17581 acagttccct ctccccattt cttgtggaga gcaatgtcac caatggacca atttgcctcg
    17641 ctagatgctg attttgcgcc agctgtaaat tgaccaaatg gaagaccgct tgactggatt
    17701 gattttgggg cagcaccgcg tttacggtct tgaagagcct gagccaaact cataccttga
    17761 ccaaaggaaa tactaccact gctatatgat gccttaaagc ttgtatttgc aggacgagcc
    17821 agaccttgat actcaagcaa gtctgaactg atttcgttaa taaaacgagt cggacggtta
    17881 taattggtac gaccaaaaag caagcgtgag ttggcattgg tcagatagag aattttctct
    17941 gcacgcgtga tacctacata ggctagacgg cgctcttctt ctaattcatc tgtatcttca
    18001 gtcgcacgac taagtggaaa gacattttct tccatcccaa tcaaaaagac aactggaaat
    18061 tcgagacctt tggcagcatg cagggtcatc aaggtcactt ctgatgtctc ctgactacct
    18121 gaatctgtgt cggcaatcaa agccaagtca tttaagaaac gactcagttt gtccagacca
    18181 gtttcctctt ctgtcacatc agtggtgtca tcaaagttct tcgtaacaga aagaaactct
    18241 tcgatatttt caacccgtgc cttgctttct agagtcgctt gggcgttaag aatatcgaca
    18301 taacctgttt tttctaggac ggactcaacc aactctgtaa tgcttaagtg gtctagctgc
    18361 tcccgcaaat caagcatcat attggcaaaa tcccagatag attgggctgc cttacccttg
    18421 ataccagaca acataatatt agcagaagca tccagcatag acatattttg caaatttgca
    18481 aaatcacgga ttttctcaac tgtacctgga ccaattccac gtttaggctc gttgataata
    18541 cgctcaaaac taatattgtc actcaaatta gcaataaggt tgagataagc aataatatcg
    18601 cgaatttcct tacggctgta gaatttggtt ccgccaacca tggtataagg aatgttagac
    18661 ttgagcaggg cttcctcaat tgtacgggac tgggcattag tccgatagag aactgcaaaa
    18721 tccttatgaa ggaagttttg actgcgacta agttcatcga tggttctggc tacaaataca
    18781 gcctcatcca gctcatcatc ggcacgatag taaacgattt gctccccatc agcgttttga
    18841 gtccagagat ttttaggacg gcgattttta ttgtttttaa taacctcgtt ggccgcttgg
    18901 agaatggttt tggttgagcg gtaattttcc tccaacaaaa caaccttggc tttggggtaa
    18961 tccttttcaa agtccaagat attctgcata tcagcaccac gccaaccgta gatagactgg
    19021 tccgcatccc caaccacaca gatattttta aaacgggaag ccaagagttt gaccaattgg
    19081 tactgagcgt ggttggtatc ttggtactca tcaacgtgga tgtattggaa tttttgctgg
    19141 tagtaggtta aaacatcagg attttgatca aagagacgca aggtcagcat aatcaaatca
    19201 tcaaagtcaa cggattcaga ctgacgaagt tctttttgat aggctgtata acactgggcc
    19261 acaatttgcg tatacatatc gccagcttgg gcagcataag caacatcatc aatcaaatca
    19321 ttcttagcat tggaaatggt ccccaaaata gttcgttcat tccatttttt aggatccaag
    19381 ttcaactgtt tgagaatacg tttcatgagc gttcgctgtt caccaggatc cacaattgta
    19441 aaattacgat tgtagccaat atggtccgca tcgcgacgca aaatacgcac acacatggag
    19501 tggaaggtcg caatcagaca gttctgagta gctggattga ggctataagc acgctctttc
    19561 atctcacgcg cagccttgtt ggtaaaggta atggccaaga tattccaagg attgaccagc
    19621 ttttcatcaa tcaaataagc gatacggtgg gttaaaacac gagtctttcc agaaccagcc
    19681 cctgccatga ttagcaaggg accttctgtc gtttgcaccg cctcagcctg acggtcattc
    19741 attccattta ataatgcgtt catcttctct tccttactct tgaagtcaat atttctatta
    19801 tatcagaaat cagggaaaat agaaacttta cggggagtag caaaatatag tggattgaaa
    19861 ctagaatact acactgtggg tttctaaaac actcgacttt tcacccaatt ttttcataaa
    19921 ctagctcaat acctcaatag acttcctgca aaactagaat cctagttcat gattgataat
    19981 accagcaata aaattcattc gtaatccgaa gcgtttacga tgatttcgat aagttgttga
    20041 aaacatttta aacgttttta ctttggcaaa gatgttctca accttgcttc tctccttaga
    20101 tagcgcatgg ttataagcct tatcttcaac tgttagcggc ttgagtttgc tggatttacg
    20161 tggagtttgt gcttgaggat atattttcat gagcccttga taaccactgt cagccaagat
    20221 tttaccagct tgtccgatat ttctgcgact cattttgaac aacttcatat catgacaata
    20281 gttcacagtg atatccaaag aaacaattct tccttgactt gtgacaatcg cttgagcctt
    20341 catagcgtga aatttctttt taccagaata attggctagt tgattttttt agggcgattg
    20401 gtttttactt ccgtcgcatc aatcattacc gtgtcctcag aactgagagg agttcttgaa
    20461 atcgtaaaac cactttgaac aagagttact tcaacccatt ggctccgacg gattaagttg
    20521 ctttcgtgaa taccaagatc agccgcaatt tgttcataag ttcgatattc tcgcacatat
    20581 tgaagagtgg ccataagaag gtcttctagg cttaatttag gttttcttcc accttttgca
    20641 tgtttaagtt gataagctgt ttttaataca gctaacatct cttcaaaagt ggtacgctga
    20701 acatcaacaa gacgcttaaa tcgtgcatca gttagttgtt tacttgcttc atcattcata
    20761 gaactactat accatgtttt gtttcgcagg aagtataata taaaaaaata aatttaagat
    20821 tggcaatacg aacgttaaac agaattccat ttctcttttt agaatcaaaa cgacaatatt
    20881 gtggaatctc tacaggaaca atagactgcg acactaaaat atcctccctt agttttactt
    20941 tactaatagt atataggagg agagccctga atcctagacc ctttgttatg atgcgcttac
    21001 aaacagagtt ggaaaaaatc ttaaaagcag aaaaacgcat gatatcagcc cctaacactt
    21061 gatacaatgc gttttattat gaaaagatct actggatttt ttatcaaaat aaacttccag
    21121 tagtcttttc actttttatt aataagttcc ttcttcacct tggctagtca agataacagg
    21181 tccatctttc gtaatgacaa attggtgttc atactgacat gacaatccac cgtcaatggt
    21241 cttatgcgcc caaccagttt tcatatctgt atcaatttcc caatcgcctg tattgatcat
    21301 tggttcaatg gttaagacca ttccttcacg aagacggagt ccacgacctg caataccata
    21361 gttaggaacc attggttctt cgtgcatagt tgggccaaca ccatgaccaa ccaaatcacg
    21421 cactacaccg taaccacgac tttcagcgta ttcttgaata gccgcaccga tatcaccgat
    21481 acgatttcca acaacagctt gctcaatacc cttgtacata gcttctttgg ttacatccat
    21541 caagtttttg acttcttcgg acggtgtacc aacagcataa gcccaacatg agtctgctaa
    21601 accaccagaa tagctctgag tatatttttt catttgttca acattgttga agtttaattt
    21661 tgagacattc aggtcagatt tagcaatggg acctcccaaa accatatcaa ctttgagcaa
    21721 atcaccatct ttcaagatat aatgacgagg gaaagcgtga gccacttcat cgttaagaga
    21781 gcaacaggta gcataaggat agtccatcat ggcaccgtca accccaatct gaagtggaag
    21841 gaaattttct tctttacaac gacggcggac atattcttca acttcccaca tatctacgcc
    21901 tggcttaatc aaatcacgta agcctatatg aatacttgct agaaaatcac cagccttgtc
    21961 catagcttcg atttcacgag ctgattttaa tgttatcatc ttttctccta gtttctaatt
    22021 aattttaaca gtcacatttg cttttgaaac aatctggtga ccatgataaa tatcgtaatc
    22081 aattatagct gaccgtctcg tatgatgaat aatccgtgcc tgaatgcgca atatatcatc
    22141 tatctgaaca gcctgcaaaa agtagatcag catctgctcg ataatgagat tgcgaccact
    22201 attaacaact aaatcttggg tcatgtgggt cagaatttct gccaatacac cattagccaa
    22261 aactccattt ttttctagca taaagggttc cactgtaatg actacttcat catggtgata
    22321 agagagcttt tgtccaatct gctcagaaaa agttggtaga gccgaaactt gggaacggct
    22381 catcttctcc atgacatctc gtcgcgtcac aacgccaagc aaagtttgat tgcttcgaac
    22441 aactggtacc atttcaaagt cttctgcgat catccgttga ctcacattgg caatatttgt
    22501 cgataatcca accaaaaata gactacgaga cataacctta tcaattgtcg tgcttggtga
    22561 tttatcacca gcgtctctca tggttacaac gccaacaacg acctgatgtt gattgataac
    22621 agggaaacgg ctgctacgat tcttacgaac caagtccaaa taatctttaa ctgtatctgt
    22681 ctctctcaga aaaccatact catgactagg gcgataaagt ttctcaactg tcagaatatc
    22741 agtcttgatt tggacatttg acaaggcttt attgatcatg gtcgcgacgg taaaggtatc
    22801 atgcttactt cttagaacag gaatcccttt ttgattggcc agtttaagca catcatcatg
    22861 aacctgaaat ccccctgtaa ccagaactgc attttcattt tccaaggcta gcaactgaat
    22921 acgggttcgg tctccgacaa tcaagagccc cccatcatga aggtaagaca agatattttg
    22981 ttcagtcatg gcaccaattg aaaacttact aaattctctc tctaaacctt cttgcccagc
    23041 cagaacctca gaagaagtca cttctgcaat ttcagcaaac gttaatctct ctatagcaac
    23101 tttctgggat ttaacacgaa ttgttccact tctaggacgg gtctccacaa ttccacggtt
    23161 ttcagcttct ttaatagccc gataggctgt tccatcacta actcctagat gattcgaaat
    23221 gctacgaaca ctgacccttt tacctactgg taattcctcc aaatagctta gaatttcctg
    23281 atgcttactc attgaactct ccttttacat accgaaattc aagataatcc cgcatttttc
    23341 ttgtgtaacg atcacttccc ttaaactgac ggaacaaact aaatccagac ttaagagcaa
    23401 ctctttggct agcttcattt tcaaggtggg taatgataga taattgtttt aagccaaatt
    23461 cctcaaaaga aagctgacaa atttttctaa caacctctgt cataaatcct tgcgaccaag
    23521 catcttttct caaaaaatag ccaagctcag cttctttttt gatttcatct aacttctcaa
    23581 atttaataga accaatcatt tgttgatttt tctggtcaca aattgcccac actcccaaag
    23641 gggacttcat aaagtaattg gccagtgcat attgactttc ttccagactt gcctgcgttg
    23701 ggaaaataaa ttgaagattt tctggatttg aagctatctc gcggaagtcc tgactatcac
    23761 taaaaaagaa aggacgcaaa tacaagcgat ccgtttcaaa aaaagaaaac attgctaatt
    23821 tggtccaaat attcataaac acctctacgg tttaatcctc aacaagtcta atatccgctc
    23881 ctaaattacg taatttttcg ataatatcag aataaccacg taagataaac tcgatattgg
    23941 taatttcagt tttaccttca gccataagcc cagcaatgac tagtgcagcc ccagctctta
    24001 agtcggtcgc tttaacactg gccccacgta aatcacgtcc acccgtgtac aaaatatgac
    24061 catttgttgt cgaaatatcc gcatccatct ttgctagttc aaaaacatga tttacacgtt
    24121 tttcgtaaat cgtatcgaca attgtaccac gaccattcgc tcttagtaaa agaggggtaa
    24181 gcggttgttg caaatcagtt gcaaagcctg ggtaaggagc tgtcttaata ttgattgctt
    24241 tcaaattaga ctgttcctcg acaaaaatgc tgtcttcaga tacagtcatt ctcactccca
    24301 tttcttccaa cttagcaata aacccttcca ggtgttcgta aagaacatta tttatacgaa
    24361 ttcctttacc aactgcagca gctaaagata tatatgttcc agcttcaatg cggtctggaa
    24421 tcacctgatg acgtgtccca tgtaatcttt caacaccatc aataatgatg atattagttc
    24481 ctgccccacg gatatgggca cccatattat tcaagagagt agctacatca ataatctcag
    24541 gttcacgggc tgcattttca ataatagtac gaccatttgc tttaaccgca gcaatcatcg
    24601 tattaatcgt tgctcccaca ctaaccgtat ccatgtaaat acttgcacca tgaagtcctg
    24661 tatctttagc agataacttc atgttatctc cctcgtagct agcagtggca cccatagctt
    24721 caaacgcctt aaggtgtaag tcaatcggac gaggaccaag atcacatcct cccggtagac
    24781 caactgtcgc ttcaccaaaa cggcctaaga ggctcccata aaaatagtaa gatgcacgaa
    24841 gactgttaat tttaccataa ggcattggaa tattttgaac acctcttgga tcaatctcca
    24901 agacatcgtc ataacgctta acagtagctc ccatcaattc catgatttcg acaagactgg
    24961 ctacatccga aatatctgga acacaatcca aagtcaccac atcatcagcc aagataatag
    25021 ctggaattaa ggccacaaca ctatttttag caccactaat agtaatttca ccttgcagtg
    25081 gtaatccacc attgataaca atttttctca ttctaagttt tcaatactct ttcaagattt
    25141 ctaataaggt cttcaaaata aagtatatca taaatttatc cttttttcca tccttttcaa
    25201 ttttattgga taaatcagag ttgacgagtt agtaactgaa ttactaatac tcaataaaaa
    25261 tcaaaga
//
LOCUS       DAVBOD010000023        25169 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 640-05
            SAMEA1012484-rid20186543.denovo.023, whole genome shotgun sequence.
ACCESSION   DAVBOD010000023 DAVBOD010000000
VERSION     DAVBOD010000023.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012484
            Sequence Read Archive: ERR059358
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 25169)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25169)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979948.1
            Genome Coverage       :: 595x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:03:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,266
            CDSs (total)                      :: 2,219
            Genes (coding)                    :: 2,091
            CDSs (with protein)               :: 2,091
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 71 of 128
            Pseudo Genes (incomplete)         :: 50 of 128
            Pseudo Genes (internal stop)      :: 33 of 128
            Pseudo Genes (multiple problems)  :: 22 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25169
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012484-rid20186543.denovo.023"
                     /strain="NIG 640-05"
                     /db_xref="taxon:1313"
     gene            89..1264
                     /gene="mutY"
                     /locus_tag="VQ862_001088"
     CDS             89..1264
                     /gene="mutY"
                     /locus_tag="VQ862_001088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="A/G-specific adenine glycosylase"
                     /protein_id="HET3115447.1"
                     /translation="MLDLKEYGIVMWPEEKVISFREKLLAWYDENKRDLPWRRSKNPY
                     HIWVSEIMLQQTRVDTVIPYYERFLDWFPTVESLATAPEESLLKAWEGLGYYSRVRNM
                     QAAAQQIMTDFGGQFPNTYEGISSLKGIGPYTAGAISSIAFNLPEPAVDGNVMRVLAR
                     LFEVNHDIGIPSNRKIFQAMMEILINPDRPGDFNQALMDLGSDIESPVNPRPEESPVK
                     DFSAAYQNGTMDRYPIKSPKKKPVPIYLKALVVKNSQGQFLLEKNESEKLLAGFWHFP
                     FIEVDNFSQEEQFDLFHQVAEESVNSGPSPEESFQQDYDLDVDWLDVCFDTVQHVFSH
                     RKWHVQIVAGQVSDFHDFSDREVRWLSPEEFKNYPLAKPQQKIWQAYAQANLDSSQD"
     gene            1320..2024
                     /locus_tag="VQ862_001089"
     CDS             1320..2024
                     /locus_tag="VQ862_001089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000722069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET3115448.1"
                     /translation="MKKILIVDDEKPISDIIKFNMTKEGYEVVTAFNGREALEQFEAE
                     QPDIIILDLMLPEIDGLEVAKTIRKTSSVPILMLSAKDSEFDKVIGLELGADDYVTKP
                     FSNRELQARVKALLRRSQPMPVDGQEADSKPQPIQIGDLEIVPDAYVAKKYGEELDLT
                     HREFELLYHLASHTGQVITREHLLETVWGYDYFGDVRTVDVTVRRLREKIEDTPSRPE
                     YILTRRGVGYYMRNNA"
     gene            2017..3366
                     /gene="vicK"
                     /locus_tag="VQ862_001090"
     CDS             2017..3366
                     /gene="vicK"
                     /locus_tag="VQ862_001090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall metabolism sensor histidine kinase
                     VicK"
                     /protein_id="HET3115449.1"
                     /translation="MLDLLKQTIFTRDFIFILILLGFILVVTLLLLENRRDNIQLKQI
                     NQKVKDLIAGDYSKVLDMQGGSEITNITNNLNDLSEVIRLTQENLEQESKRLNSILFY
                     MTDGVLATNRRGQIIMINDTAKKQLGLVKEDVLNRSILELLKIEENYELRDLITQSPE
                     LLLDSQDINGEYLNLRVRFALIRRESGFISGLVAVLHDTTEQEKEERERRLFVSNVSH
                     ELRTPLTSVKSYLEALDEGALCETVAPDFIKVSLDETNRMMRMVTDLLHLSRIDNATS
                     HLDVELINFTAFITFILNRFDKMKGQEKEKKYELVRDYPINSIWMEIDTDKMTQVVDN
                     ILNNAIKYSPDGGKITVRMKTTEDQMILSISDHGLGIPKQDLPRIFDRFYRVDRARSR
                     AQGGTGLGLSIAKEIIKQHKGFIWAKSEYGKGSTFTIVLPYDKDAVKEEVWEDEVED"
     gene            3368..4177
                     /locus_tag="VQ862_001091"
     CDS             3368..4177
                     /locus_tag="VQ862_001091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HET3115450.1"
                     /translation="MSEIGFKYSILASGSSGNSFYLETSKNKLLVDAGLSGKKITSLL
                     AEINRKPEDLDAILITHEHSDHIHGVGVLARKYGMDLYANEKTWQAMENSKYLGKVDS
                     SQKHIFEMGKTKTFGDIDIESFGVSHDAVAPQFYRFMKDDKSFVLLTDTGYVSDRMAG
                     IVENADGYLIEANHDVEILRSGSYAWRLKQRILSDLGHLSNEDGAEAMIRTLGNRTKK
                     IYLGHLSKENNIKELAHMTMVNQLAQADLGVGVDFKVYDTSPDTATPLTEI"
     gene            4268..4510
                     /locus_tag="VQ862_001092"
     CDS             4268..4510
                     /locus_tag="VQ862_001092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001853822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
                     /protein_id="HET3115451.1"
                     /translation="MTTITLKVSEADKTFMKAMAKFEGVSLSELIRTKTLEALEDEYD
                     ARVANLAYQEYLEDLEKGVEPITWEEMMHDLGLKDE"
     gene            4512..4766
                     /locus_tag="VQ862_001093"
     CDS             4512..4766
                     /locus_tag="VQ862_001093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HET3115452.1"
                     /translation="MYKLVPTRRFIKQLKKLDRYTQKLITNYLQTNVLEGPRRHGKAL
                     VGNRVGQWRYRIGNYRVIVQIVDDELVVATLEVGHRRDIY"
     gene            4813..5556
                     /locus_tag="VQ862_001094"
     CDS             4813..5556
                     /locus_tag="VQ862_001094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000731134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ion transporter"
                     /protein_id="HET3115453.1"
                     /translation="MKKKCFFADYYDTTIILLALISVILVLLGFAEMIDLDNPPYSII
                     DLVIWGVFVIDYSWRFFITKRKWRFILENIFDLLAILPLNAIFTVFRLGRIFRLVKLT
                     KLLKLTRLLRIIGLIGKLERKISRFLRTNGLIYILYVNIFIVLVGSSILSVVEEKSFS
                     DSLWWALVTVTTVGYGDVVPTSIFGKWLAVLLMLVGIGTIGMLTSTLTNFFVKDNPDE
                     QIKLDKLKDELSSQRILIEKQSEKIEELH"
     gene            complement(5846..6832)
                     /locus_tag="VQ862_001095"
     CDS             complement(5846..6832)
                     /locus_tag="VQ862_001095"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019768616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HET3115454.1"
                     /translation="MTSTKQHKKVILVGDGAVGSSYAFALVNQGIAQELGIIEIPQLH
                     EKAVGDALDLSHALAFTSPKKIYAAQYSDCADADLVVITAGAPQKPGETRLDLVGKNL
                     AINKSIVTQVVESGFKGIFLVAANPVDVLTYSTWKFSGFPKERVIGSGTSLDSARFRQ
                     ALAEKLDVDARSVHAYIMGEHGDSEFAVWSHANIAGVNLEEFLKDTQNVQEAELIELF
                     EGVRDAAYTIINKKGATYYGIAVALARITKAILDDENAVLPLSVFQEGQYGVENVFIG
                     QPAVVGAHGIVRPVNIPLNDAETQKMQASAKELQAIIDEAWKNPEFQEASKN"
     gene            7026..9494
                     /gene="gyrA"
                     /locus_tag="VQ862_001096"
     CDS             7026..9494
                     /gene="gyrA"
                     /locus_tag="VQ862_001096"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003244540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA gyrase subunit A"
                     /protein_id="HET3115455.1"
                     /translation="MQDKNLVNVNLTKEMKASFIDYAMSVIVARALPDVRDGLKPVHR
                     RILYGMNELGVTPDKPHKKSARITGDVMGKYHPHGDSSIYEAMVRMAQWWSYRYMLVD
                     GHGNFGSMDGDSAAAQRYTEARMSKIALEMLRDINKNTVDFVDNYDANEREPLVLPAR
                     FPNLLVNGATGIAVGMATNIPPHNLGETIDAVKLVMDNPEVTTKDLMEVLPGPDFPTG
                     ALVMGKSGIHKAYETGKGSIALRSRTEIETTKTGRERIVVTEFPYMVNKTKVHEHIVR
                     LVQEKRIEGITAVRDESNREGVRFVIEVKRDASANVILNNLFKMTQMQTNFGFNMLAI
                     QNGIPKILSLRQILDAYIEHQKEVVVRRTRFDKEKAEARAHILEGLLIALDHIDEVIR
                     IIRASETDAEAQAELMSKFKLSERQSQAILDMRLRRLTGLERDKIQSEYDDLLALIAD
                     LADILAKPERVSQIIKDELDEVKRKFSDKRRTELMIGQVLSLEDEDLIEESDVLITLS
                     NRGYIKRLDQDEFTAQKRGGRGVQGTGVKDDDFVRELVSTSTHDHLLFFTNKGRVYRL
                     KGYEIPEYGRTAKGLPVVNLLKLDEDESIQTVINVESDRSDDAYLFFTTRHGIVKRTS
                     VKEFANIRQNGLKALNLKDEDELINVLLAEGDMDIIIGTKFGYAVRFNQSAVRGMSRI
                     ATGVKGVNLREGDTVVGASLITDQDEVLIITEKGYGKRTVATEYPTKGRGGKGMQTAK
                     ITEKNGLLAGLMTVQGDEDLMIITDTGVMIRTNLANISQTGRATMGVKVMRLDQDAQI
                     VTFTTVAVAEKEEVGTENETEGEE"
     gene            9494..10237
                     /gene="srtA"
                     /locus_tag="VQ862_001097"
     CDS             9494..10237
                     /gene="srtA"
                     /locus_tag="VQ862_001097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sortase SrtA"
                     /protein_id="HET3115456.1"
                     /translation="MSQKNNKKKNKRKNLLTNILAGFLILLSLALIFNTQIRNIFIVW
                     NTNKYQVSQVSKEKLEENQDTEGNFDFDSVKAISSEAVLTSQWDAQKLPVIGGIAIPE
                     LEMNLPIFKGLDNVNLFYGAGTMKREQVMGEGNYSLASHHIFGVDNANKMLFSPLDNA
                     KNGMKIYLTDKNKVYTYEIREVKRVTPDRVDEVDDRDGVNEITLVTCEDLAATERIIV
                     KGDLKETKDYSQTSDEILTAFNQPYKQFY"
     gene            10481..11278
                     /locus_tag="VQ862_001098"
     CDS             10481..11278
                     /locus_tag="VQ862_001098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000254803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate/nitrite transporter family protein"
                     /protein_id="HET3115457.1"
                     /translation="MVSSEFISKIEFACNKKESLYSQSKFKYAIRSMFAGAFLTFSTA
                     AGAVGADLINKIAPGSGRFLFPFVFAWGLAYIVFLNAELVTSNMMFLTAGSFLKKISW
                     RKTAEILLYCTLFNLIGALIAGWGFAHSAAYANLTHDSFISGVVEMKLGRSNELVLLE
                     AILANIFVNIAILSFILVKDGGAKLWLVLSAIYMFVFLTNEHIAANFASFAIVKFSVA
                     ADSIANFGVGNMLRHWGVTFIGNFIGGGFLMGLPYAFLNKNEDTYVD"
     gene            11426..12685
                     /locus_tag="VQ862_001099"
                     /pseudo
     CDS             11426..12685
                     /locus_tag="VQ862_001099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015604466.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="O-acetylhomoserine
                     aminocarboxypropyltransferase/cysteine synthase"
     gene            12781..14055
                     /locus_tag="VQ862_001100"
     CDS             12781..14055
                     /locus_tag="VQ862_001100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001002592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2130 domain-containing protein"
                     /protein_id="HET3115458.1"
                     /translation="MNEIKCPNCGEVFTVNESQYAELLSQVRTAEFDKELHDRMRQEL
                     ALAEQKAMNEQQTKLAQKDQEIAQLQSQIQNFDTEKELAKKEVEQTSHQALLAKDKEV
                     QALENQLATLRLEHENQLQKTLSDLEKERNQVKNQLLLQEKENELSLASVKQNYEAQL
                     KAASEQVEFYKNFKAQQSTKAIGESLEQYAESEFNKVRSFAFPNAYFEKDNKVSSRGS
                     KGDFIFRECDENGVEIISIMFEMKNEADGTEKKHKNADFYKELDKDRREKNCEYAVLV
                     TMLEADNDYFNTGIVDVSHEYEKMYVVRPQFFIQLIGLLRNAALNSLKYKQELALVRE
                     QNIDITHFEEDLDAFKLAFAKNYNSASTNFGKAIDEIDKAIKRMEEVKKFLTTSENQL
                     RLANNKLEDVSVKKLTRKNPTMKAKFEALKGE"
     gene            14065..14943
                     /gene="truB"
                     /locus_tag="VQ862_001101"
     CDS             14065..14943
                     /gene="truB"
                     /locus_tag="VQ862_001101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007516878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(55) synthase TruB"
                     /protein_id="HET3115459.1"
                     /translation="MNGIINLKKEAGMTSHDAVFKLRKILGTKKIGHGGTLDPDVVGV
                     LPIAVGKATRMAEFMQDEGKIYEGEITLGYSTTTEDASGEVIAETPVLSPLDEKLVDE
                     AIASLTGPITQIPPMYSAVKVNGRKLYEYARAGQEVERPERQVTIYQFERTSPISYDG
                     QLARFTFRVKCSKGTYIRTLSVDLGEKLGYAAHMSHLTRTSAAGLQLEDALALEEIAE
                     KVEAGQLDFLHPLEIGTGDLVKVFLTPEEATEVRFGRFIELDQTDKELAAFEDDKLLA
                     ILEKRGNLYKPRKVFS"
     gene            15184..15486
                     /locus_tag="VQ862_001102"
     CDS             15184..15486
                     /locus_tag="VQ862_001102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000985087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HET3115460.1"
                     /translation="MMRNEFRERVEQLLQQKEINENSELSHLFRLAIQNLDRNEKYQT
                     VMANLSQGLSLYLMTHHYQAPKSVIDFGLWIAKAPSQERGRLAFLQMLAQTLQGFR"
     gene            15594..16232
                     /gene="udk"
                     /locus_tag="VQ862_001103"
     CDS             15594..16232
                     /gene="udk"
                     /locus_tag="VQ862_001103"
                     /EC_number="2.7.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uridine kinase"
                     /protein_id="HET3115461.1"
                     /translation="MQNRPIIIGVTGGSGGGKTSVSRAILSHFPDEKISMIEHDSYYK
                     DQSHLTFEERVKTNYDHPFAFDTDLMIEQIKELLAGRPVDIPTYDYTEHTRSSKTYRQ
                     EPQDVFIVEGILVLEDKRLRDLMDIKIFVDTDDDVRIIRRIKRDMEERGRSLDSVINQ
                     YLGVVKPMYHQFIESTKRYADIVIPEGVSNTVAIDLLTTKIAKILEEARNSK"
     gene            16360..17700
                     /locus_tag="VQ862_001104"
     CDS             16360..17700
                     /locus_tag="VQ862_001104"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000417449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="HET3115462.1"
                     /translation="MEKYLSVTTLTKYLKMKFDKDPYLERVYLTGQVSNFRKRPTHQY
                     FSLKDDHAVIQATIWSGIYQKLGFDLEEGMKINVIGRVQVYEPSGSYSIIIEKAEPDG
                     VGALAIQFEQLKKKLTEEGLFQERFKQALPQFSKRIGVVTSRSGAVIRDIITTVSRRF
                     PGVDILLYPTKVQGEGAAEEIARNIARANQRDDLDLLIIGRGGGSIEDLWAFNEEIVV
                     RAIFESRLPVISSVGHETDVTLADFVADRRAATPTAAAELATPVTKLDVLAHLQNQEK
                     RMVTAVRNVLSKKQEALKKCSQSVIFRQPERLYDGYLQRLDQLQLRLKQSLRTRISDN
                     KQLVQARTHQLVQLSPVTKIQRYQDRLGQLDKLLGSQMALVYDAKVAEAKRLSEALLM
                     LDTSRIVARGYAIVKKEESVVDSVESLKKKDQVTLLMRDGQVELEVKDVKTKEI"
     gene            17678..17890
                     /locus_tag="VQ862_001105"
     CDS             17678..17890
                     /locus_tag="VQ862_001105"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="HET3115463.1"
                     /translation="MSKQKKFEENLAELETIVQSLENGEIALEDAITAFQKGMVLSKE
                     LQATLDKAEKTLVKVMQEDGTESDFE"
     gene            17887..18762
                     /locus_tag="VQ862_001106"
     CDS             17887..18762
                     /locus_tag="VQ862_001106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HET3115464.1"
                     /translation="MKKQEKLALVESALEDFYGDQQFASSLRESVLYSIHAGGKRIRP
                     FLLLEVLEALQVAIKPAHAQVATALEMIHTGSLIHDDLPAMDDDDYRRGRLTNHKKFG
                     EAMAILAGDALFLDPYALIAQADLPSQIKVDLIANLSLASGSLGMVAGQVLDMEGEHQ
                     HLSLEELQTIHANKTGKLLAYPFQAAAIIAELSPEMQVKLKTVGELIGLAFQVRDDVL
                     DVTASFEEIGKTPQKDLQAEKSTYPALLGLEESIAFCNQTLDQANEKLEEIAQQVPFE
                     TESIVSVVESLRING"
     gene            18755..19570
                     /locus_tag="VQ862_001107"
     CDS             18755..19570
                     /locus_tag="VQ862_001107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001041085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlyA family RNA methyltransferase"
                     /protein_id="HET3115465.1"
                     /translation="MAKERVDVLAYKQGLFETREQAKRGVMAGLVVAVLNGERFDKPG
                     EKIPDDTELKLKGEKLKYVSRGGLKLEKALQVFDLSVDGATTIDIGASTGGFTDVMLQ
                     NSAKLVFAVDVGTNQLAWKLRQDPRVVSMEQFNFRYAEKTDFEQEPSFASIDVSFISL
                     SLILPALHRVLADQGQVVALVKPQFEAGREQIGKNGIIRDAKVHQNVLESVTAMAVEV
                     GFSVLGLDFSPIQGGHGNIEFLAYLKKEKSASNQILAEIKEAVERAHSQFKNE"
     gene            19563..19994
                     /locus_tag="VQ862_001108"
     CDS             19563..19994
                     /locus_tag="VQ862_001108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001034407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HET3115466.1"
                     /translation="MNKKERLEKIRRLVTDYQIGTQEEIVEHLKEAGITATQATVSRD
                     IKELGIVKIPLRDNTYVYELPKSIVKSLQLAEDNIESAELMDKMINLQVIPGNTAFVK
                     AQLIETFADKIFSCLTDDSSILVIARSGSLAEEIFEQVKNW"
     gene            20001..21668
                     /gene="recN"
                     /locus_tag="VQ862_001109"
     CDS             20001..21668
                     /gene="recN"
                     /locus_tag="VQ862_001109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecN"
                     /protein_id="HET3115467.1"
                     /translation="MLLEISIKNFAIIEAISLNFEKGMTVLTGETGAGKSIIIDAMNM
                     MLGARATTDVIRHGAPKAEIEGLFSVENSRLLQEIFDEQGLELGDEIIIRREILQNGR
                     SISRVNGQMVNLSVLRAIGQHLVDIHGQHDHEELMRPQLHIQMLDEFGDAAFWDLKET
                     YQTSFDAYRKMRKQVLEVKKNQQEHKARIEMLEFQMAEIEAANLQAGEDLALNQERDK
                     LLNHKNIADTLTNAYSMLDNEDFSSLANVRSAMNDMESVEEYDPEYREISSSLSETYY
                     VLEDISKRLEAIIEDLDFDGNRLMQVENRLDLLHTITRKYGGTVDDVLLYFAKITEEY
                     NLLTGNNLSSEDMEAELKKLEVNLVNLAGQLASARHNLAQQLEAEIKQELQDLYMEKA
                     QFQVRFSKGKFSREGNEMVEFYISTNPGEDFKPLVKVASGGELSRLMLAIKSAFSRKE
                     GKTSIVFDEVDTGVSGRVAQAIAQKIHKIGQYGQVLAISHLPQVIAIADYQFFIEKIS
                     NDHSTVSTVRLLTVEERVEEVAKMLAGDDVTEAALTQARELLRNREK"
     gene            21670..22398
                     /locus_tag="VQ862_001110"
     CDS             21670..22398
                     /locus_tag="VQ862_001110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000133310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine protein phosphatase"
                     /protein_id="HET3115468.1"
                     /translation="MTDYYVIGDVHGKAGMLEDLLKTWDGQTQLLFLGDLIDRGEDSH
                     RVLEMVKDLVDNQGAICLSGNHEYMFLTWLDDPEESYDHYRRNGGDTTINSILGRPLD
                     APVDGVEDAKRVAAEAADLVEFIRQMPFVVETDKYIFVHAGIDLTLDDWHETTDYKKV
                     WLRKPFHGAENHTGKTIVFGHTPVYGLLQQERGTSELWTTEDGKIGMDGGAVYGGVLH
                     GIVFTDQGMTEHHFIENDGFVAED"
     gene            22477..24300
                     /gene="lepA"
                     /locus_tag="VQ862_001111"
     CDS             22477..24300
                     /gene="lepA"
                     /locus_tag="VQ862_001111"
                     /EC_number="3.6.5.n1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001047203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor 4"
                     /protein_id="HET3115469.1"
                     /translation="MNLEELKKRQEKIRNFSIIAHIDHGKSTLADRILEKTETVSSRE
                     MQAQLLDSMELERERGITIKLNAIELNYTAKDGETYIFHLIDTPGHVDFTYEVSRSLA
                     ACEGAILVVDAAQGIEAQTLANVYLALDNDLEIMPIINKIDLPAADPERVRTEIEDVI
                     GLDASEAVLASAKAGIGIEEILEQIVEKVPAPTGDVTAPLKALIFDSVYDAYRGVILQ
                     VRVMDGVVKPGDKIQLMSNSKTFDVAEVGIFTPKAVGRDFLATGDVGYIAASIKTVQD
                     TRVGDTVTLATNPAAEPLHGYKQMNPMVFAGLYPIESNKYNDLREALEKLQLNDASLQ
                     FEPETSQALGFGFRCGFLGLLHMDVIQERLEREFNIDLIMTAPSVIYKVNLTDGESMD
                     VSNPSEFPDPTKIATIEEPYVKAQIMVPQEFVGAVMELAQRKRGDFVTMDYIDDNRVN
                     VIYQIPLAEIVFDFFDKLKSSTRGYASFDYELSEYRPSKLVKMDILLNGDKVDALSFI
                     VHKDFAYERGKLIVDKLKKIIPRQQFEVPIQAAIGHKIVARTDIKALRKNVLAKCYGG
                     DVSRKRKLLEKQKAGKKRMKSIGSVEVPQEAFLSVLSMDEE"
     gene            complement(24504..24584)
                     /locus_tag="VQ862_001112"
                     /pseudo
     CDS             complement(24504..24584)
                     /locus_tag="VQ862_001112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            24758..>25169
                     /locus_tag="VQ862_001113"
     CDS             24758..>25169
                     /locus_tag="VQ862_001113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HET3115470.1"
                     /translation="MVLDYFFDKNLVFCLEADNQEQLFDQVASLLEEREIVTPTYREA
                     LITREKSFPTGLDMEFLGKDLPNVAIPHTDIVHNLAEKVVVVRLEKPVTFHNMIAPGK
                     EVEVSLLFFIINNSSSSQTNILAQLMDFFTGNGHL"
BASE COUNT         7630 a         4439 c         5790 g         7310 t
ORIGIN      
        1 agtagataga aaagttatat actatctatt gaaaatatta taaatcagat acaaagacag
       61 gtgaaacctt ctgtgttata ctagagatat gttagatttg aaagaatacg gtatcgtcat
      121 gtggccggag gagaaagtca tttctttccg tgagaaactt ctcgcttggt atgatgaaaa
      181 caaaagagat ttgccttgga ggagaagtaa aaatccttat cacatctggg tatctgaaat
      241 catgcttcag cagaccaggg tggatacagt tatcccttac tacgaaagat ttttggactg
      301 gtttccaact gtcgaaagtc tggcaactgc gcctgaggag agtttactga aagcttggga
      361 gggcttgggc tattattctc gagttcgcaa tatgcaggct gcagcccagc agattatgac
      421 tgactttggt ggccaatttc caaataccta tgaaggaatt tccagcttga aagggattgg
      481 accttacaca gcaggagcca tttccagtat tgcttttaac ttgcctgagc cagctgtaga
      541 tggtaatgtc atgcgggtct tggcgcgtct gtttgaagtc aaccacgata ttgggattcc
      601 aagtaatcga aaaatttttc aggcaatgat ggagatcttg attaatccag atcgtccggg
      661 tgattttaat caagccttga tggacttagg gtctgatatt gagtctcctg taaatcccag
      721 acctgaagaa agcccagtca aggactttag tgcggcatat cagaatggaa ccatggaccg
      781 ttatccaatt aaatctccta agaaaaagcc ggttcctatt tatcttaaag ccttagttgt
      841 gaaaaattct caaggacaat ttttacttga aaaaaatgaa agcgaaaagc tcttggcagg
      901 tttttggcat ttccccttta tagaagttga taacttttcg caagaagagc agtttgacct
      961 ctttcatcag gttgcggaag aaagtgtgaa ctctggcccc agtccagaag agagtttcca
     1021 gcaggactat gacctagatg ttgattggct tgatgtttgt tttgatacag tccagcatgt
     1081 ttttagtcat cgaaaatggc atgtacagat tgtagcaggt caggtgagtg acttccatga
     1141 tttttcagat agggaagttc gttggctttc accagaagaa ttcaagaatt acccacttgc
     1201 caaaccccaa caaaaaatct ggcaggctta tgcacaagcc aacttagaca gtagccaaga
     1261 ctagctattg tgtcttctga ctattttttt ggtataatag tagagaaaaa ggtgaacata
     1321 tgaaaaaaat actaattgta gatgatgaga aaccaatctc ggatattatc aagtttaata
     1381 tgaccaagga aggttacgaa gttgtaactg cttttaatgg tcgtgaagcg ctagagcaat
     1441 ttgaagcaga gcaaccagat attattattc tggatttgat gcttccagaa attgatggtt
     1501 tagaagttgc taagaccatt cgtaagacaa gcagtgtgcc cattcttatg ctttcagcca
     1561 aagatagtga atttgataag gttatcggtt tggaacttgg ggcagatgac tatgtaacga
     1621 aacccttctc caatcgtgag ttgcaggcgc gtgttaaagc tcttctgcgt cgttctcaac
     1681 ctatgccagt agatggtcag gaagcagata gtaaacctca acctatccaa attggggatt
     1741 tagaaattgt tccagacgcc tacgtggcta aaaaatatgg cgaagaacta gacttaaccc
     1801 atcgtgaatt tgagcttttg tatcatttag catcgcatac aggtcaagtc atcacgcgcg
     1861 aacacttgct tgagactgtc tggggttatg actattttgg tgatgtccgt acagttgatg
     1921 tgactgtacg acgtctgcgt gagaagattg aagatacgcc cagccgacca gagtatatct
     1981 tgacacgccg tggtgtaggg tattacatga gaaataatgc ttgatttact gaaacaaacc
     2041 atttttacca gagattttat ctttatcctg attttgttag gtttcatcct tgttgtgacc
     2101 ctcttattac tggaaaatag acgtgataat attcagttga agcaaatcaa tcaaaaggtt
     2161 aaagatttga ttgcaggaga ttattccaag gttcttgata tgcaaggtgg gtctgaaatc
     2221 accaatatta ccaataattt gaatgacttg tcggaggtta ttcgtctcac tcaggaaaat
     2281 ctagaacaag agagtaagag gctaaatagt attctgtttt atatgacaga tggggttctt
     2341 gcgaccaacc gtcggggtca gattatcatg attaacgata cagccaagaa gcaactgggg
     2401 ttggttaagg aagatgttct gaatagaagc attttggaat tgctcaagat agaagaaaac
     2461 tatgaattgc gtgatttgat tacccaaagt ccagaattgt tgctagattc ccaagatatc
     2521 aatggtgaat atttgaacct tcgagttcgc tttgccttga tacgtcgaga gtctggcttt
     2581 atttcaggtt tggtggctgt tttgcatgat acgacggagc aggagaagga agaacgcgaa
     2641 cgaagactct ttgtttccaa tgttagccat gagttacgga ctcctctgac tagcgtaaaa
     2701 tcctatcttg aagccttgga tgagggggct ttgtgtgaaa ctgtagcacc agactttatc
     2761 aaggtttctc ttgatgagac caaccgtatg atgcgcatgg tgacggatct cctccatctt
     2821 tcacgtattg ataatgctac cagtcaccta gatgtggaac tgattaactt cactgctttt
     2881 attaccttta tcctcaatcg ttttgacaag atgaaaggac aggaaaagga gaaaaaatat
     2941 gagttggtga gagattatcc catcaattct atctggatgg aaattgatac agataagatg
     3001 acgcaggttg tcgacaatat tttaaataat gctattaaat attcgccaga tgggggtaaa
     3061 atcactgtca gaatgaagac aactgaagac cagatgattt tatccatttc tgaccacggt
     3121 ttggggattc ctaagcagga tttaccacgt atctttgacc gtttctatcg tgtggatcgt
     3181 gctagaagtc gtgcacaagg tggtacaggt ctaggactgt ctatcgctaa agaaattatc
     3241 aaacaacata agggctttat ttgggccaag agtgaatacg gcaagggttc aacctttacc
     3301 attgtgctcc cttatgataa ggatgcagtg aaagaagaag tatgggagga tgaagtagaa
     3361 gactagaatg agtgaaatag gctttaaata cagtatttta gcgtcgggtt ccagtggaaa
     3421 ttctttttat ctggaaacct caaaaaataa gcttttagta gatgcaggct tgtctggcaa
     3481 gaaaattacc agtctgctag ctgaaattaa ccgtaagcca gaagacctgg atgccatctt
     3541 gattacccat gagcattcag atcatatcca tggagtaggc gttttggctc gcaagtatgg
     3601 tatggatctt tatgccaatg aaaagacctg gcaagctatg gaaaatagta aatatcttgg
     3661 caaggtggat tcttcgcaaa agcatatttt tgaaatgggt aaaaccaaaa cctttggaga
     3721 tatcgacatc gagagttttg gtgtaagcca tgatgcagtc gcaccgcagt tctatcgctt
     3781 tatgaaggat gataagagtt ttgtcctttt gacagataca ggttatgtca gtgaccgtat
     3841 ggcgggcatt gtcgaaaatg cggatggcta tcttatcgag gccaaccatg atgtagagat
     3901 tttgcgatca ggttcttacg cttggcgact caaacaacga atcctatctg accttggtca
     3961 cctttctaac gaggacggtg ctgaagctat gattcggacg ctaggaaatc gtactaagaa
     4021 gatttacctt gggcatttat ctaaggaaaa taatatcaag gaactggctc atatgaccat
     4081 ggtcaatcag ctggctcaag ctgatctggg agtcggagta gactttaagg tttatgatac
     4141 ctcaccagat accgcaacac cattgacaga gatataaaaa gaacgctgag aaggtgttct
     4201 ttttatattg actgaacacc taaaaagtaa tacaatggtg ttaccattaa aaaagggagc
     4261 acaaaagatg actactatta cattaaaagt ttctgaagct gataaaacat ttatgaaagc
     4321 aatggctaag tttgaaggag tttccctttc ggaacttatt cgcaccaaaa ctcttgaagc
     4381 cctagaagat gaatacgatg ctcgtgtggc aaatttagcc tatcaagagt atttagaaga
     4441 cttggaaaaa ggagttgaac ccattacttg ggaagaaatg atgcatgatt taggcttgaa
     4501 ggatgaataa tttgtataaa ttagttccaa caagacgttt tatcaagcaa ttgaaaaaat
     4561 tggaccgtta tacgcagaag ctaattacaa actatttaca aaccaatgtt ttggaaggcc
     4621 caagacgaca cggaaaggct ttggttggta atcgcgttgg tcaatggcgc tatagaattg
     4681 gtaattatcg agttatcgta caaattgtag atgatgaatt agtcgttgct actctagaag
     4741 ttggtcatcg gagagatatt tattgaatta aagctgagta ataacaatat agaaagtaag
     4801 gagagtaaaa atttgaagaa aaaatgcttt tttgcagatt attatgatac aacaattatt
     4861 ttacttgctt taatctctgt tattttggta ttacttggat ttgctgagat gattgatttg
     4921 gacaatccgc cttatagtat tattgattta gtaatctggg gtgtttttgt aattgattat
     4981 agttggcgct tttttattac taaaagaaaa tggcgcttta ttcttgaaaa tatttttgat
     5041 ttattggcta ttctcccttt aaatgctatt ttcacagttt ttcgattagg gcgtatcttt
     5101 cgtttagtta aactaacaaa attactgaaa ctgactcgtt tacttagaat aattggactt
     5161 ataggtaaat tagaaagaaa aattagtaga ttcttacgga caaatggcct gatttatatc
     5221 ttatatgtta atatctttat tgttctagta gggagttcga ttttatccgt tgttgaagaa
     5281 aaatccttct cagatagtct ctggtgggct cttgtgacgg taactactgt tggttatggt
     5341 gatgttgttc ctacttcaat ttttggtaaa tggttagctg tcttattaat gcttgtcggt
     5401 attgggacaa taggaatgtt aacgagtacc ttgacgaact tttttgtaaa ggataatcca
     5461 gatgaacaga taaaacttga taaactcaaa gacgaattat cgagccaaag aatattaata
     5521 gagaaacaat ctgaaaaaat cgaagaacta cattgaatga taaaagactt agttgaaaaa
     5581 atatcataaa ggtgagacaa aacaaaactt gattcgagga gaaatcaagt aagtcttgac
     5641 acaatagaac gcatattatc aggtataaaa acttgatact atgcgtttta tagagaaata
     5701 aaataaaatc tgaacaaatc aattaggaat ttaaagcatt ttataacaac gttttagagt
     5761 gatagggtgc tatttcaact tcaacctact ataatacaga aaaaaaacaa ctccctgatg
     5821 attcaaggag ttgtctatag ttaaattagt ttttagaagc ttcttggaat tctggatttt
     5881 tccatgcttc gtcaataata gcttgcaatt ctttagcaga tgcttgcatt ttttgagttt
     5941 ctgcatcgtt caatggaatg tttactggac gaacgatacc atgtgcacca acaacagctg
     6001 gttgaccgat aaagacattc tcaactccgt attgaccttc ttggaatact gaaagtggaa
     6061 gtactgcgtt ttcatcgtca aggattgctt tagtgatacg agcaagggct actgcgatac
     6121 cgtagtatgt tgcacctttt ttgttgatga ttgtgtaggc tgcatcacga acaccttcga
     6181 acaattcaat caattcagct tcttgaacat tttgagtgtc tttaaggaat tcttcaaggt
     6241 ttacaccagc gatgttagcg tgtgaccaaa cagcgaactc agagtcaccg tgttcaccca
     6301 tgatgtaggc gtgcactgaa cgagcatcca catccaattt ttcagcaagt gcttgacgga
     6361 aacgagctga gtcaagtgaa gtacctgaac cgataacgcg ttctttaggg aaaccagaga
     6421 atttccaagt tgagtaagtc aaaacgtcaa ctgggttagc agcaacaagg aagatacctt
     6481 tgaaaccaga ttcaacaact tgagttacga ttgatttgtt gatagcaagg tttttaccta
     6541 caaggtcaag acgagtttca cctggttttt gaggtgcacc tgcagtgatc acaacaaggt
     6601 cagcgtctgc acagtcagag tattgagctg catagatttt tttaggtgaa gtgaaggcaa
     6661 gggcgtgact aaggtcaagc gcatcaccaa cagctttttc atgcaattgt ggaatttcga
     6721 taattccaag ctcttgtgca attccttggt taacaagtgc aaaagcgtaa gatgaaccta
     6781 cagcaccatc accgacaagg ataacttttt tgtgttgttt agttgaagtc attgttttaa
     6841 acatctcctt aattttatta ggggattttc cctagacaac ttcattctat cacttttaaa
     6901 aaactttgtc acgaatatgc cttatagttc tcgatgtaaa cgttttagtg gtttagaggc
     6961 tgaaatagat gggaatttat ggtataatgt tgttacttac taattgtgaa atgaggcatt
     7021 tattaatgca ggataaaaat ttagtgaatg tcaatctgac aaaggagatg aaggcaagtt
     7081 ttatcgacta cgccatgagt gttatcgtag cgcgagctct tcctgatgtt cgagatggct
     7141 taaaacctgt tcaccgtcgc attctctacg gaatgaatga attgggtgtg accccagaca
     7201 aaccccataa aaaatctgct cgtattacag gggatgtcat gggtaaatat cacccacacg
     7261 gggattcctc tatttatgaa gccatggtcc gtatggctca atggtggagc taccgttaca
     7321 tgcttgtaga tggtcacggg aattttggtt ccatggatgg agatagtgct gccgctcaac
     7381 gttataccga ggcacgtatg agcaagattg ctctggaaat gcttcgtgat atcaacaaaa
     7441 atacagttga tttcgttgat aactatgatg ccaatgaacg ggaacccttg gtcttgccag
     7501 cgcgttttcc aaaccttttg gttaatggag caactggtat cgcggttggg atggcaacca
     7561 atattccacc tcataatctg ggtgaaacca ttgatgcagt gaagttggtc atggataatc
     7621 ctgaagtgac taccaaggac ttgatggaag tcttgcctgg accagatttt ccaactggtg
     7681 ctcttgtcat ggggaaatca ggtatccata aggcttatga aacaggtaaa ggttcgattg
     7741 ccctacgttc tcgtacagag attgaaacga ctaagactgg tcgtgagcgc atcgttgtaa
     7801 cagaatttcc ttacatggtc aataaaacca aggtgcatga gcatattgtt cgcttggttc
     7861 aggaaaaacg cattgagggt atcacagcag tacgtgatga gtcaaaccgt gaaggtgttc
     7921 gatttgttat tgaagtcaag cgcgacgcct cagccaatgt tattctcaat aacctcttca
     7981 aaatgaccca aatgcaaacc aattttggtt tcaatatgct cgctatccaa aatggtatac
     8041 cgaaaatttt gtctcttcgt cagattttgg atgcttatat cgagcaccaa aaagaagtgg
     8101 ttgttcgtcg tacacgtttt gataaggaaa aagcggaagc gcgcgctcat atcttagaag
     8161 gtctcttgat tgcgctagac catatcgacg aagtgattcg tatcatccgt gctagtgaaa
     8221 cggatgcgga agctcaagct gagttgatga gcaagtttaa gctttctgaa cgtcaaagtc
     8281 aagctatcct tgatatgcgt cttcgtcgtt tgacaggttt ggaacgcgat aagattcaat
     8341 ctgagtatga tgacctcttg gctctgattg cggatttagc agatattctt gctaagcctg
     8401 aacgtgtttc tcaaattatc aaagacgaat tggatgaagt taaacgtaaa ttttctgata
     8461 agcgccgtac agagttgatg attggacagg tcttgagtct cgaggatgag gacttgattg
     8521 aagaatcgga tgtcttgatt accctttcta acagaggcta cattaagcgt ttggatcagg
     8581 acgagttcac tgctcaaaaa cgtgggggtc gtggtgtcca aggaacggga gtgaaagatg
     8641 atgactttgt tcgtgagtta gtgtcaacta gcacccatga tcatctgctc ttcttcacaa
     8701 acaagggacg tgtctatcgt cttaaaggtt atgaaattcc tgagtatggt cggactgcca
     8761 aagggctacc agtagtcaat ctcttgaaat tggatgaaga cgaaagtatt cagacggtta
     8821 tcaatgttga gtctgatcgc agtgatgatg cttatctctt ctttacaacc cgtcacggta
     8881 ttgtgaagag aaccagtgtt aaggagtttg ccaatattcg tcaaaatggt ctcaaagcgc
     8941 tgaatttaaa ggatgaagat gagttaatca atgtcttgtt ggcagaagga gatatggata
     9001 ttatcattgg taccaagttt ggttatgcag ttcgctttaa tcaatcagcc gttcgtggta
     9061 tgagtcgtat cgccactggt gtaaaaggtg ttaaccttcg tgaaggagac acagttgttg
     9121 gtgccagctt gattactgat caagatgagg ttcttattat cacagaaaaa ggatatggta
     9181 agcgtacagt cgctactgaa tacccaacaa aaggtcgtgg tggtaaggga atgcagacag
     9241 ctaaaattac cgaaaaaaat ggcttgctgg ccggtcttat gactgttcaa ggggatgagg
     9301 atttgatgat tatcactgat acaggtgtca tgattcgaac caatcttgcc aatatttcac
     9361 aaacaggacg tgcaactatg ggagttaaag taatgcgcct ggatcaagat gctcagatag
     9421 tgactttcac aacggttgcg gtggcagaaa aagaagaagt tgggacagaa aacgaaacag
     9481 aaggtgaaga ataatgtctc aaaaaaataa taaaaagaaa aacaagcgaa aaaatctgct
     9541 gacaaatatc ctagcaggat ttctgatatt actgtcactg gctttgattt ttaatactca
     9601 aattcgaaat attttcatag tctggaatac caataagtat caagttagcc aggtatcaaa
     9661 agaaaaatta gaagaaaatc aggatacaga aggcaatttt gactttgatt ctgtcaaagc
     9721 tatctcttcg gaagctgttc taacttctca atgggatgct caaaaattac cagttattgg
     9781 gggaattgca attcctgaat tggaaatgaa tttgccgatt tttaaaggac ttgataatgt
     9841 taatctcttc tacggagctg gtacaatgaa acgcgagcaa gtaatgggag aaggaaatta
     9901 tagtctagct agtcaccata tctttggtgt tgataatgct aataaaatgt tattttctcc
     9961 tttagataat gctaaaaatg gcatgaagat ttatctaacc gataaaaata aagtttatac
    10021 ttatgaaata cgtgaagtca aacgtgtgac accggatcgt gttgatgaag ttgatgatag
    10081 agatggggtc aatgaaatca cattagtaac ctgtgaagac cttgctgcta cagaacgtat
    10141 tattgtcaaa ggtgatttga aagaaacaaa agattattca caaacatctg atgaaattct
    10201 aacagctttc aatcaaccat ataaacaatt ttattaatac aaatcagtga aatcatggat
    10261 ttcactgatt ttttaagatt ttcataaaaa tatagtaaaa tgaaataaga ataggacgaa
    10321 tcgttcagga cagtcaaatc gatttctaac aatgttttag aagtagaggt gtactattct
    10381 agtttcaatc tactataaac ttttatgaaa tacagaaaac gcttcctaaa acctaaagtt
    10441 tgtgatataa ttatcaagaa aaaagattta ggagtttatt atggtttctt cagaatttat
    10501 ctcaaagatt gaatttgctt gcaataagaa agaaagtctt tatagtcaaa gcaaatttaa
    10561 gtatgcgatt cgttcgatgt tcgcaggtgc atttttaacc ttcagtactg ctgcaggtgc
    10621 agttggggct gacttgatta ataaaattgc accaggtagt ggacgcttcc tctttccatt
    10681 cgtttttgct tggggcttgg cctacattgt ttttttgaat gccgagttgg tcacttcaaa
    10741 catgatgttc ttgactgctg gtagtttctt aaaaaaaatc tcttggagaa aaacagctga
    10801 gattttacta tactgtacct tgttcaacct tatcggagcc ttgatagcag ggtggggctt
    10861 tgctcattcg gcagcctatg cgaatctgac acacgatagt ttcatctcag gtgttgttga
    10921 gatgaagtta ggccgctcaa atgaattggt cttgcttgag gcgattttgg caaatatttt
    10981 cgtaaatatt gcgattctgt catttatttt ggtcaaagat ggtggtgcca aactttggct
    11041 tgtgttgtca gctatttaca tgtttgtatt cttaacaaac gagcacattg cggcgaactt
    11101 tgcttctttc gcgattgtga aattcagtgt tgctgcggat tcaattgcca acttcggtgt
    11161 tggaaatatg cttcgccact ggggtgtgac tttcatcgga aactttatcg gaggaggctt
    11221 cttgatgggt cttccatatg ccttcctcaa taaaaacgaa gatacttatg tagattaaga
    11281 aaatgagcac gattgagtcg tgcttttttc attttcaaaa taaggtaata gctatttctt
    11341 atatcaaaat atagaaaact gatatttgta aactataact caaggtgcta caatatcctt
    11401 aataaaatga tatggaggtc accttatgac ttgtgatttt aaatctgaaa ctctacaact
    11461 acatgctggt caagttgtgg ctccagctac taagtctcgt gcagtgccga tttatcaaac
    11521 aacatttttt gtttttgatg acacgtagga aggtgccgat ctgtttgcct tgaggaaacc
    11581 agggaacatt tatactcgta tcaccaatcc tacaacagct gcccttgaag gtggtgttga
    11641 agcgctagca acagcatcag gtatgactgc agtgacttat acgattttgg cgcttgccca
    11701 tgctggtgac catgtagtgg ctgcttcgac tatttacggt ggaaccttca atcttttgaa
    11761 agaacccctt cctcgttatg gtatcacaac aacctttgtc gatgttgata atttggagga
    11821 agtagaagca gttatcaaag acaataccaa gcttgtcttg attgaaacct tgggtaactc
    11881 cttgattaat attccagacc tggaaaaact ggcagagatt gctcataaac atcaaatccc
    11941 acttgtgtca gacaatactt ttgcaatacc ttatttgatt aacgtcttct ctcatggcgt
    12001 tgacattgcc attcactctg cgactaagtt tatcggtggg catggtacaa ctattggagg
    12061 aataattgtc gatagtggtc gttttgactg gatggcttca gggaaattcc ctcaatttgt
    12121 tgacgagggt tcaagctgcc acaatttgag ctatactcgt gatgtgggtg cagtagcctt
    12181 tattatagct gttcgagttc aattgctttg tgatacaggt gcagccttgt caccattcaa
    12241 tgctttcctc ttgctacaaa gacttgaaac cctttcactt cgtgtggaac gccatgtaca
    12301 aaatgctgag acaattgttg attttcttgt caaccatcct aaggtagaaa aggtaaatta
    12361 tccaaaactt gcagatagtc cttatcatgc attggctgag aaatacttgc caaaaggtgt
    12421 cggttcaatc tttaccttcc acgtcaaagg tgacgaggaa gaagcacgca aggccattga
    12481 taatttagaa atcttttctg accttgcaaa cgcggcagat gctaaatcgc ttgttgtcca
    12541 tccagcaaca atcactcacg gtcaattgtc agaaaaagac ctagaagcag caggtgtcac
    12601 accaaatcaa atccacttgt ctatcggtct tgaaaatgta gaagatttga ttgaagactt
    12661 acgcttagcc ttggaaaaaa tttaaagtaa aagaagataa acagtgggtt ttgactcact
    12721 gtttttgatt ttccctcagg catgatataa tggttacaga agtctagaaa gaggaatgta
    12781 atgaacgaaa tcaaatgtcc caactgtggg gaagtcttta cagtaaatga aagccagtat
    12841 gctgaacttt tgtcccaagt gagaacggca gagtttgata aggaactaca cgataggatg
    12901 aggcaggaac tggccttggc tgagcaaaag gctatgaatg agcaacagac taaactggct
    12961 cagaaggatc aagaaattgc gcaattgcag agtcaaatcc aaaactttga tacagaaaaa
    13021 gaattggcca agaaagaagt tgaacagaca agccatcagg ccttattggc taaggacaag
    13081 gaagtacagg ccttggaaaa ccagttggcg accttgcgtt tggagcatga aaatcaattg
    13141 caaaagaccc tttctgacct agaaaaagaa cgcaatcagg tcaaaaatca gctcctactg
    13201 caagaaaagg aaaatgagtt gtctttggct tctgttaagc aaaactacga agcccagctc
    13261 aaagcagcca gtgaacaagt cgagttttat aagaatttta aggctcaaca atctacaaaa
    13321 gcgattgggg aaagcctaga acagtatgca gagagtgagt ttaacaaggt tcgtagtttc
    13381 gcctttccaa atgcttactt tgagaaggat aacaaggtct cttcgcgtgg gtctaaaggg
    13441 gactttatct tccgtgagtg tgatgaaaat ggagttgaaa tcatttctat catgtttgag
    13501 atgaaaaatg aagcggacgg aacagagaag aagcacaaga atgcagattt ttacaaggaa
    13561 ttggacaagg accgtcggga gaagaactgt gagtatgccg ttttggtgac catgcttgag
    13621 gctgataatg actactttaa cacagggatt gttgacgtca gtcacgagta tgaaaaaatg
    13681 tatgttgttc gtcctcaatt ctttatccaa ttgattggtc tcttacgtaa tgcggcgcta
    13741 aattccctaa aatacaagca ggagttggcc ttggttcgcg agcaaaatat tgacattacg
    13801 cattttgagg aagatttgga tgcctttaag ctagcttttg ctaagaacta taattcagct
    13861 tcgactaact ttggaaaagc tattgatgaa atcgacaagg ccatcaaacg catggaagag
    13921 gttaagaaat tcctgactac atctgaaaac caactccgtc tagctaacaa caaattggaa
    13981 gatgtctctg ttaaaaaatt gacccggaaa aatccaacaa tgaaagcgaa gttcgaagca
    14041 ctgaaggggg agtagaaagc aaaaatgaac ggtattatca acttaaaaaa agaagcagga
    14101 atgacctcgc atgatgcggt ttttaaactg cgtaagattt tgggaaccaa gaaaattggt
    14161 catggtggaa ccttggatcc ggatgtggtg ggtgttttgc cgattgcggt tggcaaggcg
    14221 acacgcatgg ccgagtttat gcaggacgag ggtaagatct atgaggggga aattactctg
    14281 ggttattcca cgacgactga ggatgctagt ggggaagtga tcgcagaaac ccctgttttg
    14341 tctcccttgg atgaaaagct tgttgatgaa gcgattgcta gcttgactgg gcctattacc
    14401 cagattcccc ctatgtattc ggcagttaag gttaatggtc gcaagctcta tgagtatgcg
    14461 cgtgctggtc aggaagtgga gcgtccagaa cgtcaggtga ccatttatca atttgagcga
    14521 acaagtccga tttcttatga tggccaactt gcccgattca cttttcgtgt aaaatgcagt
    14581 aaagggactt acatccgtac tttgtcagtt gatttgggtg aaaagcttgg ttatgcggct
    14641 catatgtccc atttgactcg tactagtgct gctggcttac aattagaaga cgctcttgcc
    14701 ttggaggaaa ttgctgaaaa agtagaggct gggcaattag attttctcca tcctttagag
    14761 attgggacag gtgaccttgt caaagttttc ctaactccag aagaggctac agaagttcgc
    14821 tttggtcgtt ttattgagct agaccaaacg gacaaagaac tggctgcctt tgaagatgat
    14881 aaattgttag ccattctaga aaaacggggc aatctctata agccaaggaa ggtttttagc
    14941 tagatcgttt aggaataaaa atcgggtgat agataacaat tgcttgctaa aaccccatac
    15001 taatagtaga atggttttgg gaattataat attccaattg ttgcgagttg taggtactca
    15061 aataatctat atagaaattt agaggtgtga aatgaagcaa tttaaaattc tttcagataa
    15121 atatttagag tccattacag gttctggtgg gaacttaggc ccagaatttg gtgtgataat
    15181 tccatgatgc gaaatgagtt tcgagaaagg gtggagcaac ttcttcaaca aaaagaaata
    15241 aatgaaaata gtgagttgag tcacctgttt cgtcttgcta tacaaaattt agacagaaat
    15301 gaaaaatacc aaacggtcat ggccaatttg agtcaagggt tgtcacttta cctcatgacg
    15361 catcattacc aggcacctaa gtctgtcatt gattttggtt tatggattgc caaagctcct
    15421 agccaggaaa gagggagact ggctttcttg cagatgcttg ctcaaaccct acagggcttt
    15481 cgttaaaact gtcgaacatc agagggaaga ctctggtgtt ttttgctgat gagactataa
    15541 attttgtaaa aaatgtgata gaatagacga cggataaaat aacggaggat agcatgcaaa
    15601 atagaccaat cattattgga gtgacaggtg gttctggtgg tggtaaaacc agtgtttcaa
    15661 gagccatttt atcgcatttt cctgatgaaa agatttccat gattgagcat gattcatact
    15721 acaaggatca gtctcatttg acctttgaag agcgtgtcaa aaccaactat gaccatcctt
    15781 ttgcctttga tacagacttg atgatcgagc agattaagga attgttggca gggcgtccgg
    15841 tggacatccc gacctacgac tatacagagc atacacggag tagcaagacc tatcgtcagg
    15901 agcctcaaga tgtctttatc gttgagggca ttttggtctt ggaggacaag cgtctgcgcg
    15961 atttgatgga tatcaagatt tttgtggata cggatgacga tgtgcgcatt attcgtcgta
    16021 tcaagcgtga tatggaggag cgtggccgta gccttgatag cgttattaac cagtacttag
    16081 gtgtggtcaa accaatgtac caccagttta tcgagtcaac taagcgttat gctgatatcg
    16141 tcattcctga aggggttagc aataccgtgg ctatcgacct gttgacgacc aagattgcaa
    16201 agattttgga agaagctcga aacagcaaat aatcacatgt ggaggccttg cctccttttt
    16261 ctatttttcc ctcataatgg tacataaatg gagattttta ggcatatttt tggtataata
    16321 atacccatga aagagcaagt aaatgaatag taggtggaga tggaaaagta tttatcggta
    16381 acaactttga ccaagtatct gaaaatgaaa ttcgataaag acccatactt ggaacgggtc
    16441 tatttaactg gtcaagtttc caactttcgt aaacgaccta ctcaccaata tttctcccta
    16501 aaggatgacc atgcagttat tcaagcgacc atctggtctg ggatttatca gaaattaggg
    16561 tttgacctgg aagaaggaat gaagatcaat gtgattgggc gtgtacaggt ttatgaacca
    16621 agtggtagct actccatcat cattgaaaaa gctgagcctg atggggttgg ggcgcttgcg
    16681 attcagtttg aacaacttaa gaaaaaattg acagaagaag gcctgtttca agaacgcttc
    16741 aagcaagctc tgccccaatt ttctaagaga attggggtag taaccagccg tagtggagcc
    16801 gttattcgag atattatcac gaccgtcagc aggcgattcc caggtgttga catccttctt
    16861 tatccgacca aggttcaagg tgaaggggct gcggaggaaa ttgctagaaa tattgcgcgt
    16921 gctaatcaac gggacgattt ggatttgctc attattggtc gtggaggtgg ttctattgag
    16981 gatctctggg cctttaacga agaaattgtg gtacgagcta tttttgaatc tcgtttgcca
    17041 gttatctcta gtgtggggca tgaaacggat gtgaccttgg cagattttgt ggcagatcga
    17101 cgcgctgcaa cgccaacagc ggcggctgaa ctggcaacac ctgtgaccaa gttggatgta
    17161 ttagctcatt tgcaaaatca ggaaaaacgg atggtaacgg cagtccgaaa tgttctatct
    17221 aagaaacaag aggctttgaa aaaatgcagt cagtctgtta tctttagaca acctgagcgc
    17281 ttgtatgacg gttatttgca acgcttggac caactgcaac tgcgtttgaa acaaagtttg
    17341 cgaactcgga tttctgataa caaacaatta gttcaagcaa gaactcatca attagtacaa
    17401 ttatcacctg ttaccaaaat ccaacgctat caagaccgtt taggacagtt ggacaagctc
    17461 ttaggtagcc aaatggcgtt agtttatgac gccaaggttg ctgaggccaa gcgactttcg
    17521 gaagctttgc tcatgttgga tactagccga atcgtggcgc gtggttatgc tattgtcaaa
    17581 aaagaagagt ccgttgtaga ttcggttgag agtttgaaga aaaaagacca agtaacgctt
    17641 ttgatgcgag atggtcaagt agaattagag gttaaagatg tcaaaacaaa agaaatttga
    17701 ggaaaatcta gcagaactgg aaaccattgt ccaaagtttg gaaaatggtg aaattgctct
    17761 ggaagatgcg attactgcct ttcaaaaggg catggtcttg tcaaaagagc tccaagctac
    17821 gctggacaag gctgaaaaga ccttggtcaa ggtcatgcaa gaagacggaa cagaaagtga
    17881 ttttgaatga aaaagcaaga aaaattagct cttgtcgagt cggctttgga agatttttat
    17941 ggagaccagc agtttgcctc tagtttacgg gagtctgttc tctattctat tcatgctggt
    18001 ggcaagcgta ttcggccttt tctcttgtta gaagttctgg aagccctgca ggttgccatc
    18061 aaacctgctc acgcgcaggt agctactgcc ttggagatga ttcatacagg gagcttgatt
    18121 cacgatgacc ttcctgctat ggatgatgac gattatcgaa gagggcggtt aaccaatcac
    18181 aagaaattcg gtgaagctat ggccattttg gctggagatg ccttattctt agacccatat
    18241 gccttgattg cgcaggcaga tttgccaagt cagatcaagg tggacttgat tgccaactta
    18301 tcccttgctt caggtagtct gggtatggtg gcagggcaag ttttggatat ggagggcgaa
    18361 caccagcact tgtctctgga agaacttcag actattcatg ccaataagac tgggaagtta
    18421 ctagcctatc ccttccaagc ggcagctatt atagctgaat tgtcacctga aatgcaggtg
    18481 aagctgaaaa ctgtgggtga attgattgga cttgcttttc aagtcagaga tgatgtactg
    18541 gatgtgacag ctagttttga ggaaatcggt aagacacctc aaaaggatct gcaggcagaa
    18601 aaatcaacct atcctgcctt gttgggcttg gaagagtcca ttgccttttg taaccaaacc
    18661 ctggatcaag ctaatgaaaa attggaagaa attgcccagc aggttccctt tgaaacagaa
    18721 tcgattgtaa gtgtagtaga aagtttgaga atcaatggct aaggaaagag tggatgtact
    18781 agcttataaa caggggttgt ttgaaacgag agagcaggcc aagcgaggtg tgatggctgg
    18841 cctagtcgta gcagtcctta atggagaacg gtttgacaag ccaggagaga aaattccaga
    18901 tgataccgaa ttaaaactca agggggagaa actcaagtat gtcagccgtg gtggtttgaa
    18961 actggaaaag gccttgcagg tctttgattt gtcggtggat ggcgcgacta cgattgatat
    19021 cggggcctct actggaggtt ttaccgatgt catgctacag aatagtgcca agttggtctt
    19081 tgcagtcgat gttggtacca atcagttggc ttggaaatta cgccaagacc cacgagttgt
    19141 cagcatggag cagttcaatt tccgctatgc tgaaaagact gatttcgagc aggagccgag
    19201 ctttgccagt attgatgtga gtttcatttc ccttagtctg attttgccag ccttgcaccg
    19261 tgtcttggct gatcaaggtc aggtggtagc acttgtcaaa cctcagtttg aggcaggacg
    19321 tgagcagatt gggaaaaatg gaattattcg agatgctaag gttcatcaga atgtccttga
    19381 atctgtaaca gctatggcag tagaggtagg tttttcagtc cttggcttgg acttttctcc
    19441 catccaaggt ggacatggaa atattgaatt tttagcgtat ttgaaaaaag aaaagtcagc
    19501 aagcaatcag attcttgctg agattaaaga agcagtagag agggcgcata gtcaatttaa
    19561 aaatgaataa aaaagagaga cttgaaaaaa ttagaagatt ggtgacagat tatcaaatcg
    19621 gcacgcaaga agaaattgta gaacatttga aagaagcagg tatcactgcc actcaggcga
    19681 cggtatcccg agatatcaaa gagttaggta ttgtcaaaat tcctttgaga gacaacacct
    19741 atgtctacga attgccaaaa tcaatcgtaa aaagtctgca actggctgaa gacaatatcg
    19801 aatcggctga attgatggat aagatgatca atctccaagt tattccagga aatacggctt
    19861 ttgtaaaagc tcagttaatc gagacttttg cagacaagat ttttagctgt ttgactgatg
    19921 atagctcgat tttagtcatt gccagaagtg gaagtctagc agaggaaatc tttgaacaag
    19981 taaaaaattg gtaggtctat atgttacttg aaatttcgat aaaaaacttt gccattattg
    20041 aggctatttc cctcaatttt gaaaagggga tgactgtcct gactggtgaa acgggtgcag
    20101 ggaagtcgat tatcattgat gccatgaata tgatgttggg agctcgtgcg acgacagatg
    20161 ttattcgtca tggtgcacca aaggcagaga ttgaggggct tttctcagtt gagaatagtc
    20221 gtcttttaca ggaaattttt gatgagcaag gtttagaatt aggtgatgaa attatcatcc
    20281 gtcgggaaat cttgcaaaat ggtcgtagta tcagccgtgt aaatggtcag atggttaatc
    20341 tgtctgtttt gcgagctatt gggcaacatc ttgtagatat tcatggtcag catgaccatg
    20401 aggagttaat gcgtccccaa ctgcatatcc agatgttgga tgaatttggt gatgccgctt
    20461 tttgggactt gaaagaaacc tatcaaacga gttttgatgc ctatcggaaa atgcgcaagc
    20521 aggttctgga agtcaagaaa aaccaacagg aacacaaggc acgtatcgaa atgttggaat
    20581 ttcaaatggc agagattgag gcagcaaact tgcaggctgg agaagacttg gctctcaatc
    20641 aagagcgaga taaactcctc aaccacaaaa atattgcgga tacactgacc aatgcctaca
    20701 gtatgttgga caatgaagat ttttcaagtc tggccaatgt tcgttcagct atgaatgaca
    20761 tggaaagtgt cgaagagtat gatcctgaat accgtgaaat ttcaagctct ctgtctgaga
    20821 cctactatgt tttagaagac attagcaaac gtttggaagc tatcattgag gaccttgatt
    20881 ttgatggcaa tcgcctcatg caggttgaga atcgtttgga cctccttcat actattactc
    20941 gtaagtatgg tgggactgtt gatgatgttt tgctttattt tgccaagatt acggaagaat
    21001 acaatctctt gacaggcaat aatctttcgt ctgaggacat ggaagcagag cttaagaagt
    21061 tggaagtcaa tcttgtcaat ttggcaggtc aacttgcttc tgctcgtcat aatttggctc
    21121 agcaactcga agctgagatt aaacaagaac tgcaagatct ttatatggaa aaagcccagt
    21181 ttcaggttcg ttttagtaag ggaaaattca gtcgtgaggg aaatgaaatg gttgagtttt
    21241 atatttcaac caaccctgga gaagacttta aacccttggt taaggttgct tctggagggg
    21301 aattatctcg tctcatgtta gccattaagt ctgccttttc acgtaaagaa ggcaagacta
    21361 gcattgtctt tgatgaggtg gatacgggag tttcaggtcg tgttgctcaa gctattgctc
    21421 agaaaattca taaaattggt cagtatggtc aggttttggc tatctcccat ttgccacaag
    21481 taattgcgat tgcagattat caattcttta ttgagaagat tagtaatgac cattcaacgg
    21541 tttcgactgt tcgtctcttg acagtcgaag agcgagtgga ggaagttgcc aagatgttgg
    21601 caggtgatga tgtgacagaa gcagccctga cgcaagccag agaattgttg agaaacaggg
    21661 agaaataaga tgacagatta ttatgtaatt ggagatgttc acggaaaagc tgggatgctg
    21721 gaagaccttc ttaaaacctg ggatggtcag acccagttgc tctttctagg tgatttgatt
    21781 gacagaggtg aggatagtca ccgtgttctt gaaatggtca aggacttggt ggacaatcaa
    21841 ggggctatct gtttgtctgg aaaccacgag tatatgtttt tgacttggct agatgaccca
    21901 gaagaaagtt atgaccatta tcgtcgcaat ggtggagata caaccattaa ctctatccta
    21961 ggtcgtccct tggatgcacc agttgatgga gtagaagatg ccaagcgggt tgccgctgaa
    22021 gcggcagact tggtcgaatt cattcgtcaa atgccatttg tagtagagac agacaagtat
    22081 atctttgttc acgcaggtat tgatttgacc ttggacgact ggcatgaaac aacagattat
    22141 aaaaaagtat ggcttagaaa accattccac ggagctgaaa atcatactgg aaaaaccatt
    22201 gtcttcggtc atacaccggt ctatggtttg ttacagcaag aacgcggtac atctgagctt
    22261 tggactacag aagatggcaa gattggaatg gatggaggag ctgtttatgg tggtgtcctt
    22321 cacgggattg tctttacaga ccaaggaatg acagaacacc actttatcga aaatgacggc
    22381 tttgtcgctg aagattagta ctcctagcag ggtatggtct tgtcaaaata tcaaaaacaa
    22441 tttataataa atagataccc tgaaaggaag agaatcatga acttagaaga attgaaaaaa
    22501 cgacaggaga agatccgtaa cttctctatt atcgcccata ttgaccatgg aaaatcaact
    22561 ctagcagacc gcattttgga aaaaacagag acggtttcaa gtcgtgaaat gcaggcccag
    22621 cttttggata gcatggagct agagcgggaa cgtggaatta ctattaagtt gaatgccatc
    22681 gagttgaatt acactgcaaa agatggggaa acttatattt tccatttgat tgacacacca
    22741 gggcacgttg actttaccta tgaagtttca cgttcgctag ctgcctgtga gggtgctatt
    22801 ttggtggtcg atgcggctca aggaattgag gctcaaactc ttgccaacgt ttatctggct
    22861 ttggataatg atttggaaat catgcctatc attaataaaa ttgacctgcc ggctgcagat
    22921 ccggagcgcg tgcgtacaga gattgaagat gtgattggtt tggatgccag tgaagcagtt
    22981 ttggcttctg ccaaggctgg tattgggatt gaagaaatcc tcgagcaaat tgtagaaaaa
    23041 gtaccagcac caacgggtga tgtgacggcg ccacttaagg ccttgatttt cgactctgtt
    23101 tacgatgctt accgtggggt tatcctccaa gtgcgtgtca tggacggagt ggtcaaacct
    23161 ggtgataaga ttcagctcat gagcaatagt aagacctttg atgtggccga agtcggtatt
    23221 tttacaccaa aagcggttgg tcgtgatttc cttgcgactg gtgatgttgg ttacattgcg
    23281 gcgtctatca agacggttca ggatactcgt gtgggtgata ccgttacctt ggcaaccaat
    23341 cctgcggcag aaccattaca tggttataag cagatgaatc ctatggtctt tgcgggtctc
    23401 tacccaatcg aatcaaacaa atacaatgac ctgcgtgaag cgcttgaaaa attgcaactg
    23461 aatgatgcta gtcttcagtt tgaaccagaa acatctcagg cacttggatt tggtttccgt
    23521 tgtggatttc ttggacttct ccatatggat gttatccagg aacgtttaga gcgtgagttc
    23581 aatattgacc tcatcatgac agctccgtct gttatttaca aagttaattt gaccgacggt
    23641 gagtctatgg atgtgtctaa cccatctgag tttccagacc caactaagat tgcgaccatt
    23701 gaagagcctt atgtcaaggc gcaaatcatg gtaccacagg agttcgtcgg agcagtaatg
    23761 gagctagctc agcgtaagcg tggggacttt gtgactatgg actatattga tgataaccgt
    23821 gtcaatgtta tctatcaaat tcctcttgct gaaattgtct ttgacttctt tgataaactt
    23881 aagtcttcga cacgtggtta tgcaagcttt gactacgaat tgtcagaata tcgcccatct
    23941 aagctggtga aaatggatat ccttctcaat ggagataagg tggatgccct cagctttatc
    24001 gttcacaagg actttgccta cgaacgtggg aaactcatcg ttgataaact caagaaaatc
    24061 atccctcgcc aacaatttga agttccaatc caagcggcta ttggacacaa gattgtcgct
    24121 cgtactgata tcaaggccct tcgtaagaac gtacttgcta aatgttatgg tggtgacgtt
    24181 tctcgtaagc gtaaactcct tgaaaaacaa aaagctggta agaaacgcat gaaatccatc
    24241 ggatcagttg aagttccgca agaagccttc ctcagcgtct tgagtatgga tgaagaataa
    24301 gttatcagaa atgcctttcc ttgttcacag gaaatttata taagaatcaa tagtaaagca
    24361 ggcttagatg gtctgctttt ttagttttta tactcttcga aaatctcttc aaaccacgtc
    24421 agcgtcgcct taccgtatgt atggttactg acttcgtcag tttcatctac aacctcaaaa
    24481 tcatgttttg agctgacttc gtcagtttca tctacaacct caaaactgtg ttttgagtaa
    24541 cctgcggcta gcttcctagt ttgctctttg attttcattg agtattagaa cagaaaaatg
    24601 cttggagtat ttgtttgtgt gtttattttt atataacaaa ctataaacaa aacaaaaata
    24661 taaaaaaaga gacaaaaaag aatagaaagt aattaacaac gatttcatat agtgttatac
    24721 ttatagcata aagttaatgg aaagaaggga aaaccttatg gtattagatt atttctttga
    24781 caaaaacctt gtgttttgct tagaagcgga taatcaagaa caactctttg atcaggtagc
    24841 aagcttgttg gaagaacgag aaattgtcac tccaacttat cgtgaagcct tgatcacgcg
    24901 tgaaaagtca tttccaactg gtttagatat ggaatttcta ggaaaggact tgccaaatgt
    24961 agcgattcct cacacagata ttgttcataa tctagctgaa aaagtggtgg ttgttcgatt
    25021 agaaaaacca gtaacttttc acaatatgat tgcgccaggt aaggaagtag aagtatccct
    25081 actcttcttt atcattaaca attcaagttc aagtcaaaca aatattctgg ctcagttgat
    25141 ggactttttc acaggaaatg gacatcttg
//
LOCUS       DAVBOD010000024        23938 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 640-05
            SAMEA1012484-rid20186543.denovo.024, whole genome shotgun sequence.
ACCESSION   DAVBOD010000024 DAVBOD010000000
VERSION     DAVBOD010000024.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012484
            Sequence Read Archive: ERR059358
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 23938)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23938)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979948.1
            Genome Coverage       :: 595x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:03:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,266
            CDSs (total)                      :: 2,219
            Genes (coding)                    :: 2,091
            CDSs (with protein)               :: 2,091
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 71 of 128
            Pseudo Genes (incomplete)         :: 50 of 128
            Pseudo Genes (internal stop)      :: 33 of 128
            Pseudo Genes (multiple problems)  :: 22 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23938
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012484-rid20186543.denovo.024"
                     /strain="NIG 640-05"
                     /db_xref="taxon:1313"
     gene            complement(90..1076)
                     /locus_tag="VQ862_001114"
     CDS             complement(90..1076)
                     /locus_tag="VQ862_001114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001145427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HET3115471.1"
                     /translation="MPVTIKDVAKAAGVSPSTVTRVIQNKSTISDETKKRVRKAMKEL
                     NYHPNLNARSLVSSYTQVIGLVLPDDSDAFYQNPFFPSVLRGISQVASENHYAIQIAT
                     GKDEKERLNAISQMVYGKRVDGLIFLYAQEEDPLVKLVAEEQFPFLILGKSLSPFIPL
                     VDNDNVQAGFDATEYFIKKGCKRIAFIGGSKKLFVTKDRLTGYEQALKHYKLTTDNNR
                     IYFADEFLEEKGYKFSKRLFKHDPQIDAIITTDSLLAEGVCNYIAKHQLDVPVLSFDS
                     VNPKLNLAAYVDINSLELGRVSLETILQIINDNKNNKQICYRQLIAHKIIEK"
     gene            complement(1086..1886)
                     /locus_tag="VQ862_001115"
     CDS             complement(1086..1886)
                     /locus_tag="VQ862_001115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000938258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1189 domain-containing protein"
                     /protein_id="HET3115472.1"
                     /translation="MLPYPFSFFSSILGFRKPLSKRFGLNWFQLLFTSIFLISLSMVP
                     IAIQNSSQETYPLETFIDNVYEPLTNEVVQDLSEHATIVDGTLTYTGTVSQASSVVIG
                     PSQIKELPKNLQLHFDTNELVISKESKELTRISYRAIQTESFKSKDSLTQAISKDWYQ
                     QNRVYISLFLVLGASFLFGLNFFIVSLGASLLLYITKKSRLFSFRTFKECYHFILNCL
                     GLPTLITLILGLFGQNMTTLITVQNILFVLYLVTIFYKTHFRDPNYHK"
     gene            complement(2147..2989)
                     /locus_tag="VQ862_001116"
     CDS             complement(2147..2989)
                     /locus_tag="VQ862_001116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001065636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HET3115473.1"
                     /translation="MNNSIKLKRRLTQSLTYLYLIGLSIVIIYPLLITIMSAFKAGNV
                     SAFKLDTNIDLNFDNFKGLFTETLYGTWYLNTLIIALITMAVQTSIIVLAGYAYSRYN
                     FLARKQSLVFFLIIQMVPTMAALTAFFVMALMLNALNHNWFLIFLYVGGGIPMNAWLM
                     KGYFDTVPMSLDESAKLDGAGHFRRFWQIVLPLVRPMVAVQALWAFMGPFGDYILSSF
                     LLREKEYFTVAVGLQTFVNNAKNLKIAYFSAGAILIALPICILFFFLQKNFVSGLTSG
                     GDKG"
     gene            complement(2991..4283)
                     /locus_tag="VQ862_001117"
     CDS             complement(2991..4283)
                     /locus_tag="VQ862_001117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000414940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HET3115474.1"
                     /translation="MEKQQPSKAALLSIIPGLGQIYNKQKAKGFIFLGVTIVFVLYFL
                     ALATPELSNLITLGDKPGRDNSLFMLIRGAFHLIFVIVYVLFYFSNIKDAHTIAKRIN
                     NGIPVPRTLKDMIKGIYENGFPYLLIIPSYVAMTFAIIFPVIVTLMIAFTNYDFQHLP
                     PNKLLDWVGLTNFTNIWSLSTFRSAFGSVLSWTIIWALAASTLQIVIGIFTAIIANQP
                     FIKGKRIFGVIFLLPWAVPAFITILTFSNMFNDSVGAINTQVLPILAKFLPFLDGALI
                     PWKTDPTWTKIALIMMQGWLGFPYIYVLTLGILQSIPNDLYEAAYIDGANAWQKFRNI
                     TFPMILAVAAPTLISQYTFNFNNFSIMYLFNGGGPGSVGGGAGSTDILISWIYRLTTG
                     TSPQYSMAAAVTLIISIIVISISMIAFKKLHAFDMEDV"
     gene            complement(4394..5665)
                     /locus_tag="VQ862_001118"
     CDS             complement(4394..5665)
                     /locus_tag="VQ862_001118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000095461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HET3115475.1"
                     /translation="MSSKFMKSTAVLGTVTLASLLLVACGSKTADKPADSGSSEVKEL
                     TVYVDEGYKSYIEEVAKAYEKEAGVKVTLKTGDALGGLDKLSLDNQSGNVPDVMMAPY
                     DRVGSLGSDGQLSEVKLSDGAKTDDTTKSLVTAANGKVYGAPAVIESLVMYYNKDLVK
                     DAPKTFADLENLAKDSKYAFAGEDGKTTAFLADWTNFYYTYGLLAGNGAYVFGQNGKD
                     AKDIGLANDGSIAGINYAKSWYEKWPKGMQDTEGAGNLIQTQFQEGKTAAIIDGPWKA
                     QAFKDAKVNYGVATIPTLPNGKEYAAFGGGKAWVIPQAVKNLEASQKFVDFLVATEQQ
                     KVLYDKTNEIPANTEARSYAEGKNDELTTAVIKQFKNTQPLPNISQMSAVWDPAKNML
                     FDAVSGQKDAKTAANDAVTLIKETIKQKFGE"
     gene            6215..7732
                     /gene="malQ"
                     /locus_tag="VQ862_001119"
     CDS             6215..7732
                     /gene="malQ"
                     /locus_tag="VQ862_001119"
                     /EC_number="2.4.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-alpha-glucanotransferase"
                     /protein_id="HET3115476.1"
                     /translation="MKKRQSGVLMHISSLPGAYGIGSFGQSAYDFVDFLVRTKQRYWQ
                     ILPLGATSYGDSPYQSFSAFAGNTHFIDLDILVEQGLLGASDLEGVDFGSDASEVDYA
                     KIYYARRPLLEKAVKRFFEVGDVKDFEKFAQDNQSWLELFAEYMAIKEHFDNLAWTEW
                     PDADARARKASALESYREQLADKLVYHRVTQYFFFQQWLKLKAYANDNHIEIVGDMPI
                     YVAEDSSDMWANPHLFKTDVNGKATCIAGCPPDEFSVTGQLWGNPIYDWEAMDKDGYK
                     WWIERLRESFKIYDIVRIDHFRGFESYWEIPAGSDTAAPGEWVKGPGYKLFAAVKEEL
                     GELNIIAEDLGFMTDEVIELRERTGFPGMKILQFAFNPEDESIDSPHLAPANSVMYTG
                     THDNNTVLGWYRNEIDDATREYMARYTNRKEYETVVHAMLRTVFSSVSFMAIATMQDL
                     LELDEAARMNFPSTLGGNWSWRMTEDQLTPAVEEGLLDLTTIYRRINENLVDLKK"
     gene            7758..10016
                     /gene="glgP"
                     /locus_tag="VQ862_001120"
     CDS             7758..10016
                     /gene="glgP"
                     /locus_tag="VQ862_001120"
                     /EC_number="2.4.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000950172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen/starch/alpha-glucan family
                     phosphorylase"
                     /protein_id="HET3115477.1"
                     /translation="MLSLQEFVQNRYNKTIAECSNEELYLALLNYSKLASSQKPVNTG
                     KKKVYYISAEFLIGKLLSNNLINLGLYDDVKKELAAAGKDLIEVEEVELEPSLGNGGL
                     GRLAACFIDSIATLGLNGDGVGLNYHFGLFQQVLKNNQQETIPNAWLTEQNWLVRSSR
                     SYQVPFADFTLTSTLYDIDVTGYETATKNRLRLFDLDSVDSSIIKDGINFDKIDIARN
                     LTLFLYPDDSDRQGELLRIFQQYFMVSNGAQLIIDEAIEKGSNLHDLADYAVVQINDT
                     HPSMVIPELIRLLTARGIELDEAISIVRSMTAYTNHTILAEALEKWPLEFLQEVVPHL
                     VPIIEELDRRVKAEYKDPAVQIIDESGRVHMAHMDIHYGYSVNGVAALHTEILKNSEL
                     KAFYDIYPEKFNNKTNGITFRRWLMHANPRLSHYLDEILGDGWHHEADELEKLLSYED
                     KAAVKEKLESIKAHNKRKLARHLKEHQGVEINPNSIFDIQIKRLHEYKRQQMNALYVI
                     HKYLDIKAGNIPARPITIFFGGKAAPAYTIAQDIIHLILCMSEVIANDPAVAPHLQVV
                     MVENYNVTAASFLIPACDISEQISLASKEASGTGNMKFMLNGALTLGTMDGANVEIAE
                     LVGEENIYIFGEDSETVIDLYAKAAYKSSEFYAREAIKPLVDFIVSDAVLAAGNKERL
                     ERLYNELINKDWFMTLLDLEDYIKVKEQMLADYEDRDAWLDKVIVNISKAGFFSSDRT
                     IAQYNEDIWHLN"
     gene            complement(11061..11633)
                     /locus_tag="VQ862_001121"
     CDS             complement(11061..11633)
                     /locus_tag="VQ862_001121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3115478.1"
                     /translation="MNKLMKFISVFLTSIVLIVSAIPSVSAVYASEQVSQIETNMELQ
                     PVTSLTEEQINTLANEIQSFHPDVSQQWIKEVINRQLQGDYTIPPTYSPFRAAWQGIT
                     VNQMGALLDTAIALALGGTTAGLANLIKVKGKHAAKSAIRSAISRYLGNWFVNDVALE
                     SAMNLLSPGTYLAQLWDKNDAIPNNGRINF"
     gene            complement(12256..13104)
                     /locus_tag="VQ862_001122"
     CDS             complement(12256..13104)
                     /locus_tag="VQ862_001122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001095523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HET3115479.1"
                     /translation="MNTNLKPKLQRFASATAFACPICQENLTLLETNFKCCNRHSFDL
                     AKFGYVNLAPQIKQSANYNKENFQNRQQILEAGFYQAILDAVSDLLASSKTTTTILDI
                     GCGEGFYSRKLQESHSEKTFYAFDISKDSVQIAAKSEPNWAVNWFVGDLARLPIKDAN
                     MDILLDIFSPANYGEFRRVLSKDGILIKVIPTENHLKEIRQRVQDQLTNKEYSNQDIK
                     EHFQEHFTILSSQTASLTKTITAEQLQALLSMTPLLFHVDQSKIDWSQLTEITIEAEI
                     LVGKAF"
     gene            13256..13534
                     /locus_tag="VQ862_001123"
     CDS             13256..13534
                     /locus_tag="VQ862_001123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003075836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3115480.1"
                     /translation="MLKEVLTVAKVAKKSSLFLGGVAFGTLGLKILASKEAKKGYSKA
                     LAKAYKLKDELDASVSVVKQHGDDVLQDAKYLYEQEKKEEQLDSLIGE"
     gene            13536..15599
                     /locus_tag="VQ862_001124"
     CDS             13536..15599
                     /locus_tag="VQ862_001124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000008803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HET3115481.1"
                     /translation="MSFKVLHRGYQHIRLSSSFSLTLDIQDYLRSLARDEKGIESIQF
                     YMDQQHFTLRIKEGFSVLDNAEAFLKRIDKGKVSELMTLPIRREESAYSIVSGAAVKR
                     VLFRSFVPYPIRYIWTCYQALGYIREAYQTLARKELTMEVLDCSAILLSLFMNQSKTA
                     SNIMFMLDLGNHLDQWSLKKTATDLEQSLLAKESDVFLVQGDTVVSIKSSDVQIGDVL
                     ILSQGNEILFDGQVVSGLGMVNESSLTGESFPVEKRESDLVCANTVLETGELRICVTD
                     NQMNSRLLQLIELMKKSEENKKTKQRYFIKMADKVVKYNFLGAGLTYLLTGSFSKAIS
                     FLLVDFSCALKISTPVAYLTVIKEGLNREMVIKDGDVLEKYLEVDTFLFDKTGTITTS
                     YPIVEKVLPFGDYSEEDILRISACLEEHIYHPIANAIVKQAEIEGIEHEEMHGKLQYI
                     ASKGIKSHIDGQPVLIGNYVLMQDEQIHISSEQNALIEEYKSHYNLLFLAYQNELIGM
                     FCIHTPLRKEAKTALDKLKAQGKKLILATGDTLTRTEELVKDLPFDQVYTDLKPDGKF
                     ELVEKLQKAGHTILMVGDGLNDSAALTLSDIGVVMNESADISKQMSDILLLDNRLDFF
                     QELDSLSSSLQTLIKKNIQDTVVVNSSLIGFGLFNWLSPSNLSILHNLTTLRIVLRSL
                     SIKNR"
     gene            complement(15677..16933)
                     /locus_tag="VQ862_001125"
     CDS             complement(15677..16933)
                     /locus_tag="VQ862_001125"
                     /EC_number="6.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000546895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine--tRNA ligase"
                     /protein_id="HET3115482.1"
                     /translation="MHIFDELKDRGLIFQTTDEEALRKALEEGQVSYYTGYDPTADSL
                     HLGHLVAILTSRRLQLAGHKPYALVGGATGLIGDPSFKDAERSLQTKDTVDGWVKSIQ
                     GQLSRFLDFENGENKAVMVNNYDWFGSISFIDFLRDIGKYFTVNYMMSKESVKKRIET
                     GISYTEFAYQIMQGYDFFVLNQDHNVTLQIGGSDQWGNMTAGTELLRRKADKTGHVIT
                     VPLITDATGKKFGKSEGNAVWLNPEKTSPYEMYQFWMNVMDADAVRFLKIFTFLSLDE
                     IEDIRKQFEAAPHERLAQKVLAREVVTLVHGEEAYKEALNITEQLFAGNIKNLSVKEL
                     KQGLRGVPNYQVQADENNNIVELLVSSGIVNSKRQAREDVQNGAIYVNGDRIQELDYV
                     LSDADKLENELTVIRRGKKKYFVLTY"
     gene            17075..19540
                     /locus_tag="VQ862_001126"
     CDS             17075..19540
                     /locus_tag="VQ862_001126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HET3115483.1"
                     /translation="MQNQLNELKRKMLEFFQQKQKNKKSARPGKKGSSTKKSKTLDKS
                     AIFPAILLSIKALFNLLFVLGFLGGMLGAGIALGYGVALFDKVRVPQTEELVNQVKDI
                     SSISEITYSDGTVIASIESDLLRTSISSEQISENLKKAIIATEDEHFKEHKGVVPKAV
                     IRATLGKFVGLGSSSGGSTLTQQLIKQQVVGDAPTLARKAAEIVDALALERAMNKDEI
                     LTTYLNVAPFGRNNKGQNIAGARQAAEGIFGVDASQLTVPQAAFLAGLPQSPITYSPY
                     ENTGELKSDEDLEIGLRRAKAVLYSMYRTGALSKDEYSQYKDYDLKQDFLPSGTVTGI
                     SRDYLYFTTLAEAQERMYDYLAQRDNVSAKELKNEATQKFYRDLAAKEIENGGYKITT
                     TIDQKIHSAMQSAVADYGYLLDDGTGRVEVGNVLMDNQTGAILGFVGGRNYQENQNNH
                     AFDTKRSPASTTKPLLAYGIAIDQGLMGSETILSNYPTNFANGNPIMYANSKGTGMMT
                     LGEALNYSWNIPAYWTYRMLREKGVDVKGYMEKMGYEIPEYGIESLPMGGGIEVTVAQ
                     HTNGYQTLANNGVYHQKHVISKIEAADGRVVYEYQDKPVQVYSKATATIMQGLLREVL
                     SSRVTTTFKSNLTSLNPTLANADWIGKTGTTNQDENMWLMLSTPRLTLGGWIGHDDNH
                     SLSRRAGYSNNSNYMAHLVNAIQQASPSIWGNERFALDPSVVKSEVLKSTGQKPGKVS
                     VEGKEVEVTGSTVTSYWANKSGAPATSYRFAIGGSDADYQNAWSSIVGSLPTPSSSSS
                     SSSSSSDSSNSSTTRPSSSRARR"
     gene            19605..20516
                     /locus_tag="VQ862_001127"
     CDS             19605..20516
                     /locus_tag="VQ862_001127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007285066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EamA family transporter"
                     /protein_id="HET3115484.1"
                     /translation="MNQYQKKIVNGKIYSLLSGLIWGICGILGEYFFTHYQVSSGWIT
                     SMRLTLAGSLVLIWSAIQLKSQVLDIWRDKKNYLPFLAYAILGIFSVQYFFYLCVEYS
                     NATTATILQFISPVFILFYNRLVYQKRASKSAVFYVLVAMLGVCLMATKGDLSQLSMT
                     PLALITGLLSAMGVMFNVILPQPFAKRYGFVPTVGWGMILAGLFSNVLSPVYQLSFTL
                     DIWSILICLIIAFFGTAFAFFISMKAVSLVSPLVVAVISASEPLSSALLSVLFLGLVV
                     DWSLLLAIALIILPMIFLSIEEAKESR"
     gene            20746..21444
                     /gene="dapD"
                     /locus_tag="VQ862_001128"
     CDS             20746..21444
                     /gene="dapD"
                     /locus_tag="VQ862_001128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3,4,5-tetrahydropyridine-2,6-dicarboxylate
                     N-acetyltransferase"
                     /protein_id="HET3115485.1"
                     /translation="MTATKMNAQEIIQFIANAEKKTSVKVTFEGQLATAVPSSVVKLG
                     NVLFGDWKDVAPLLEGLVENQDYVVEQDARNSAVPLLDKRAINARIEPGAIIRDQVEI
                     GDNAVIMMGAVINIGAEIGAGTMIDMGAILGGRAIVGKNSHVGAGAVLAGVIEPASAE
                     PVRVGDNVLIGANAVVIEGVQIGSGSVVAAGAIVTQDVPENVVVAGVPARIIKEIDAQ
                     TQQKTALEDALRTL"
     gene            21512..22642
                     /locus_tag="VQ862_001129"
     CDS             21512..22642
                     /locus_tag="VQ862_001129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyldiaminopimelate deacetylase"
                     /protein_id="HET3115486.1"
                     /translation="MLDLIQTRRDLHQIPEIGLEEFKTQAYLLDVIEKLTTGKDFVQI
                     RTWRTGILVYLQGSQPERTIGWRTDIDGLPIVEQTGLPFASQHQGRMHACGHDFHMTI
                     ALGCLERALEEQPKNNLLFLFQPAEENEAGGMLMYEAGAFGDWLPNQFYGLHVRPDLK
                     VGQIATNTHTLFAGTCEVKIRFKGKGGHAAFPHEANDALVAASYFVTQVQSVVSRNVN
                     PIEGAVVTFGVFQAGTTNNVITDTAFLHGTIRALTQDMSLLVQKRVKTVAEGVAAAFD
                     MEVEVELKQGGYLPVENNPALACELMDFFDEKDGIELIDIEPAMTGEDFGYLLSKVDG
                     VMFWLGIDSPYALHHPQMSPKEEVLAIGVAAVSSFLKKKAAE"
     gene            22654..23193
                     /locus_tag="VQ862_001130"
     CDS             22654..23193
                     /locus_tag="VQ862_001130"
                     /EC_number="6.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-formyltetrahydrofolate cyclo-ligase"
                     /protein_id="HET3115487.1"
                     /translation="MKSELRKQVLHEMKAISQEQKQAIDQALTERLLHHPFYQEAKVI
                     ATYLSFSHEFQTRELIEQALKDGKKVLMPKTYPKGRMDFVVYDPQQLVKTSFALLEPQ
                     GDVEVVDASQIDLIHVPGLAFTTKGYRIGYGGGYYDRYLEHFSGHTLSTVHPCQIQDF
                     IPENHDIPVQEVLIDEGNL"
     gene            23177..23854
                     /locus_tag="VQ862_001131"
     CDS             23177..23854
                     /locus_tag="VQ862_001131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhomboid family intramembrane serine protease"
                     /protein_id="HET3115488.1"
                     /translation="MKEIFDRRYPVTSFFLLVTALVFLLMLVTAGGNFDRADTLFRFG
                     AMYGPAIRLFPEQVWRLLSAIFVHIGWEHFIVNMLSLYYLGRQVEEIFGSKQFFFLYL
                     LSGMMGNLFVFVFSPKSLAAGASTSLYGLFAAIIVLRYATRNPYIQQLGQSYLTLFVV
                     NIIGSVLIPGISLAGHIGGAVGGAFLAVIFPVRGEKRMYNTSQRLGAVVLFVGLAILL
                     FYKGMGL"
BASE COUNT         6998 a         4396 c         5277 g         7267 t
ORIGIN      
        1 aatcttccca cattaaaacg catagtatca agttttttca atacctgata gtatgcgttt
       61 ttgcttttaa cgactttttg tccagtctct tatttttcga taattttgtg ggcgatcaat
      121 tgacggtaac aaatttgttt attgttttta ttatcattaa taatctggag aatagtttca
      181 agggaaacac gaccaagctc taaactattg atatcgacat aggctgccaa gttgagcttg
      241 ggattaaccg agtcaaagct gagaacaggg acatccagct ggtgtttggc aatatagtta
      301 caaacacctt cagctaggag gctatcggtt gtgatgatag catcaatttg tggatcgtgc
      361 ttgaataatc gcttgctaaa tttatagccc ttttcttcca gaaactcgtc ggcaaagtag
      421 atgcgattgt tgtcagtggt aagtttgtaa tgtttaagcg cctgttcata gcctgttaaa
      481 cggtctttgg tcacgaagag ctttttactt cctccgataa aggcaatgcg tttgcagcct
      541 tttttgatga aatattcagt cgcatcaaaa ccagcttgaa cattgtcgtt gtcgacaagt
      601 gggatgaaag gagatagaga tttacctaag ataaggaagg ggaactgttc ttctgcgacg
      661 agttttacga gagggtcttc ttcttgggca tagagaaaga ttagcccatc tacacgcttg
      721 ccgtagacca tttgtgaaat agcgttgaga cgctccttct catctttccc tgttgctatc
      781 tgaatggcat agtggttttc agatgcgact tgagagatgc cacgtagaac cgatggaaag
      841 aaaggattct ggtagaaggc gtctgagtca tcaggaagaa ctaatccgat aacctgagta
      901 tagctgctta ccaagctacg agcgttgagg tttgggtggt agttgagttc cttcatagct
      961 ttgcgaacgc gtttttttgt ttcgtcgcta atggttgatt tattttgaat aacacgggtt
     1021 acggttgaag gcgaaacacc agcagccttg gccacgtctt taatcgtaac gggcataaaa
     1081 atctcctatt tatggtaatt tggatcacgg aaatgtgttt tataaaagat agtgaccaga
     1141 tacagaacaa aaagaatatt ttgtacagta atcagggttg tcatattttg gccaaataat
     1201 cccaaaataa gtgtaatcag agtcggcaat cctaaacagt tcaagataaa gtgatagcac
     1261 tctttaaagg ttctaaatga aaagaggcgt gatttcttag tgatataaag gagaagacta
     1321 gctcctagag agacgataaa gaaattcaaa ccaaagagga agctcgcacc gagaactagg
     1381 aagaggctga tatagacacg attttgttgg taccagtctt tagaaattgc ttgggtcaag
     1441 ctgtctttgc ttttgaaact ctcagtctga atggctcggt aagagatgcg ggtcagttcc
     1501 ttgctttcct tgctgatgac tagctcattt gtatcgaaat gcagttgcaa gttcttaggt
     1561 aattccttga tttgacttgg accaatcaca acagaagagg cttgactaac tgttccagta
     1621 taagttaatg tgccatcgac aattgtagca tgttcagaga gatcctggac aacctcattt
     1681 gtcagaggtt catagacatt atcgataaaa gtttctagcg gataggtctc ctgggagctg
     1741 ttttggatag caatgggtac catagacaag ctgataagga agatactggt aaagagaagt
     1801 tgaaaccagt tgagcccgaa acgtttggac aggggcttac gaaaccccaa aatacttgaa
     1861 aaaaaggaaa atggatatgg aagcataggt atctttctaa aaggtgtttt ctatataagt
     1921 attattatat agagaaatgc gctttatttc aagtctagga gaaaaattgc ttgctacaag
     1981 gatattattt acagtgacaa tcgctaatag tcaatgaaaa tcaaagtgca aaccaggaag
     2041 ctagctgcag gttgctcaaa gcacaacttt gaggttggag ataaagctga cgtggtttga
     2101 agagattttc gaagagtata aaatgaaaaa gggtggcggg gataaattat cccttgtcgc
     2161 caccacttgt aagtcctgaa acaaagttct tttgtaggaa gaagaagaga atacagattg
     2221 gaagggcgat gaggatagca cctgctgaga agtaggcaat cttcaagttt ttcgcattgt
     2281 taacgaaggt ttggagacct acggcaacag taaagtattc tttctcacga agcaagaaac
     2341 tagagaggat gtagtccccg aaaggtccca tgaaggccca gagagcttgt acggcaacca
     2401 ttgggcgaac aagtggaaga acaatttgcc agaagcggcg gaagtgtcct gcaccgtcta
     2461 gttttgcaga ttcgtctaaa gacattggca ctgtatcgaa gtagcctttc atgagccaag
     2521 cattcatcgg gataccacca ccaacgtaga ggaagatgag gaaccagttg tggttaaggg
     2581 cgttcaacat aagcgccata acgaagaagg ctgtcaaagc ggccatagtt ggcaccattt
     2641 ggatgatcaa gaagaagacc aaactttgtt tacgagccaa gaagttgtaa cggctgtaag
     2701 cataaccagc aagtacgatg atacttgttt gaacagccat ggtaattaag gcgataatca
     2761 aagtgttgag gtaccaagta ccgtacaagg tttcagtgaa gaggccttta aagttatcaa
     2821 aattgaggtc gatattagta tctagtttaa aggctgagac gttacctgct ttaaaggctg
     2881 acataatggt aatcaacagt ggatagataa ttacaattga tagaccaatc aggtaaaggt
     2941 aagtaaggct ttgagtcagt ctacgtttga gtttaattga gttattcatc ttagacgtcc
     3001 tccatatcaa atgcgtgtag tttcttgaat gcgatcatag agattgagat gacaatgata
     3061 gagataatca aggtaacagc tgccgccatt gagtattgag gagatgtacc tgttgtcaaa
     3121 cggtagatcc atgagatcaa gatatcggtt gaaccagctc cacctccgac actaccaggt
     3181 cctccaccat tgaagaggta catgatagag aagttgttaa agttgaaggt gtattggcta
     3241 atcaaagtag gtgccgcaac agccaaaatc attgggaaag tgatgttgcg gaatttttgc
     3301 caagcgttgg caccgtcaat ataagctgct tcgtaaaggt cgttaggaat agattgcaag
     3361 atacccaaag tcaaaacgta gatgtatggg aatccgagcc aaccttgcat cataatcaag
     3421 gcaatcttag tccaagttgg gtctgttttc caaggaataa gagctccatc aaggaaagga
     3481 aggaatttag ccaagattgg caatacttga gtgttgatag caccgacact atcgttaaac
     3541 atgtttgaga atgtcaagat agtgatgaag gctgggacag cccaaggaag aaggaaaata
     3601 acaccaaaga tacgttttcc tttgataaat ggttggttgg caatgatagc tgtgaagata
     3661 ccaattacga tttgtaaagt agaagctgcc aaagcccaaa tgatagtcca agaaagaaca
     3721 gaaccaaagg cagaacggaa ggtactcaag ctccaaatgt ttgtaaagtt ggtcaaacca
     3781 acccagtcca acaacttgtt tggtggcaag tgttggaagt cgtagttggt aaaggcgatc
     3841 atcaaggtta cgataactgg gaagataatc gcgaaggtca tggcaacata agatggaatg
     3901 atcaagaggt aagggaagcc attttcataa atccctttga tcatgtcttt gagtgtgcgt
     3961 ggaactggaa ttccattgtt aatgcgtttt gcaatcgtat gtgcatcttt gatatttgag
     4021 aaataaaaga gtacataaac gattacaaag attagatgga aggcaccacg aatcagcata
     4081 aagagggaat tatcacgacc tggtttgtca ccaagagtga tgaggttgct caattcaggg
     4141 gttgcaagtg ctaggaagta aaggacaaat acgatggtta caccaaggaa gataaaacct
     4201 ttggcttttt gtttattgta aatctgtcct aacccaggaa tgatagacag cagggctgct
     4261 ttactaggtt gttgcttttc catattaact cctttcatag gatactactt ttttataaga
     4321 aagctaaatt atttgtgtct ctattgataa attcaaaggg ggatttgatt tccacccccc
     4381 ttgaacaaat tttttattca ccaaattttt gtttgattgt ttctttgatc aatgttacag
     4441 catcgttagc agctgtttta gcatcttttt gaccacttac agcatcaaag agcatatttt
     4501 tcgctggatc ccaaactgca gacatttgag agatgtttgg cagtggttga gtgttcttga
     4561 actgtttgat aacagctgtt gtcaactcat cgtttttacc ttcagcgtat gaacgagcct
     4621 cagtattagc tgggatttcg ttagtcttat catataatac tttttgttgt tcagttgcaa
     4681 caaggaagtc tacaaatttt tgagaagctt caaggttctt aacggcttga ggaatgaccc
     4741 aagctttacc accaccgaat gcagcatatt cttttccatt tggaagagtt gggatagttg
     4801 caactccgta gtttacttta gcatctttaa aggcttgagc tttccaaggt ccgtcgatga
     4861 tagcagctgt tttaccttct tggaattgag tttggattaa gtttccagca ccttctgtat
     4921 cttgcatacc tttaggccat ttttcgtacc aagatttagc gtagttgata cctgcgatag
     4981 aaccgtcgtt tgcaagaccg atgtctttag cgtctttacc gttttggcca aagacgtaag
     5041 caccgttacc ggcaagaagt ccatatgtat agtagaagtt tgtccagtca gctaggaagg
     5101 cagtagtttt accatcttca ccagcgaatg cgtatttgct atctttagca aggttttcca
     5161 agtcagcaaa tgtttttgga gcatctttca ccaagtcttt gttgtagtac ataacaagtg
     5221 actcgataac ggcaggagca ccgtaaactt taccattagc agctgttaca agagatttag
     5281 ttgtgtcgtc tgttttagca ccatcgctca atttcacttc tgaaagttgt ccgtcagaac
     5341 caaggctacc tacacggtcg tatggagcca tcataacatc agggacatta ccagattggt
     5401 tgtcaagaga aagtttatca agacctccta gagcatcacc agttttaaga gtgactttta
     5461 ctccagcttc tttttcataa gctttagcaa cctcttcaat atagctctta tatccctcgt
     5521 ctacatatac agtgagttct ttgacttcag atgaaccaga atcagcaggc ttatcagcag
     5581 ttttgcttcc gcaagctacc aaaagcaagc tagcaagtgt aacagttcca agcaccgcag
     5641 tgctcttcat aaatttagat gacatagtgt attcctccca aagaatagca agttttattg
     5701 ataaggaaac gcaaacgttt tcctttatga gcttagtata gcacaaatag aaaacggttg
     5761 caagtatttt ttgtaaaaat tttaaaaaat ttttaagctt gatttgatag cataattttg
     5821 cattttaata gaagaaaagt atgaaataga taagaataca gtatttttaa taaaaatata
     5881 tggaatctgt ctaaagaggg aaaccaggag gggctacctc cctgtttcta atccctatct
     5941 attttctata gacgtttgtg ctttgttgca tataaattca agctccctaa ggaggttttg
     6001 tactttgtag actgtctcgt gagagtcaaa ctttaggatt agatagtttt aagttatctt
     6061 tgctaaaatg agttagtctc cttaaaaata atcaaaaaag ttttttaaaa acgcttgcaa
     6121 ttatgcttga aaaggagtat acttataagt aacgcaaacg tttgcgtctg caaaatacgc
     6181 aacgttccat tattttaaca cacgaggtgc tattatgaaa aaacgtcaaa gtggtgtgtt
     6241 gatgcacatc tcttctcttc caggagctta cggaatcgga tcatttggtc aaagtgctta
     6301 cgacttcgtt gatttcttgg tccgtacaaa acaacgttac tggcaaatcc ttccattagg
     6361 agcaactagt tacggggatt ctccttacca atctttctca gccttcgcag gaaacactca
     6421 ttttatcgat ttagatatct tggtggagca aggtttgttg ggagcgagtg accttgaagg
     6481 agttgacttt ggtagcgatg cgtctgaagt tgactatgct aaaatctact atgcacgtcg
     6541 tcctctttta gaaaaagcgg tgaaacgttt ctttgaagtc ggagatgtta aagattttga
     6601 gaaatttgct caagacaacc aatcatggct tgagctcttt gctgagtata tggctatcaa
     6661 agagcatttt gacaatcttg cttggactga atggccagat gcagatgctc gtgctcgtaa
     6721 agcttcagca cttgaaagct atcgtgagca attggcagac aagttggttt accaccgtgt
     6781 gactcaatac ttcttcttcc aacaatggtt gaaattgaaa gcttacgcta acgacaacca
     6841 cattgaaatc gttggggaca tgccaatcta cgtagcggaa gattcaagtg atatgtgggc
     6901 aaatccacat ctcttcaaaa cagatgtcaa tggtaaggct acttgtatcg caggatgccc
     6961 accagatgag ttttctgtaa ctggtcagct ttggggtaac ccaatctatg actgggaagc
     7021 aatggacaaa gacggctaca aatggtggat tgaacgcttg cgtgaaagct tcaaaatcta
     7081 cgatatcgtt cgtatcgacc acttccgtgg cttcgaatct tattgggaaa tccctgctgg
     7141 ttccgataca gcagcacctg gtgagtgggt gaaaggtcca ggctacaagc tttttgcagc
     7201 cgttaaggaa gaacttggtg agctaaacat catcgcagaa gaccttggct tcatgacaga
     7261 tgaagtgatc gaattgcgtg aacgtactgg cttcccagga atgaagattc ttcaatttgc
     7321 cttcaaccca gaagacgaaa gcattgatag cccacacttg gcacctgcta actcagttat
     7381 gtacacagga acacacgata acaatacggt tcttggttgg taccgtaatg agattgatga
     7441 tgcgactcgt gagtacatgg ctcgttacac gaaccgtaaa gaatacgaaa cagtggtaca
     7501 cgctatgctt cgtacagtat tttcatcagt tagctttatg gcaattgcga ctatgcaaga
     7561 tttactagaa ttggatgagg cagctcgtat gaacttccca tctacccttg gtggaaactg
     7621 gtcttggcgt atgactgaag atcaattgac accagctgtc gaggaaggtt tgcttgactt
     7681 gacaacaatt tatcgccgaa ttaatgaaaa tttggtagat ttaaagaaat aagacaataa
     7741 tcaggagaca actaaacatg ttatcactac aagaatttgt acaaaatcgt tacaataaaa
     7801 ccattgcaga atgtagcaat gaagagcttt accttgctct tcttaactac agcaagcttg
     7861 caagcagcca aaaaccagtc aacactggta agaaaaaagt ttactacatc tcagctgagt
     7921 tcttgattgg taaactcttg tcaaacaact tgattaacct tggtctttac gacgatgtta
     7981 aaaaagaact tgcagctgca ggtaaagact tgatcgaagt tgaagaagtt gaattggaac
     8041 catctcttgg taatggtggt ttgggacgtt tggctgcctg ctttatcgac tcaattgcta
     8101 ctcttggttt gaatggtgac ggtgttggtc ttaactacca ctttggtctt ttccaacaag
     8161 ttcttaaaaa caaccaacaa gaaacaattc caaatgcatg gttgacagag caaaactggt
     8221 tggttcgctc aagccgtagc taccaagtac catttgcaga ctttactttg acatcaactc
     8281 tttacgatat tgatgttact ggttatgaaa cagcgactaa aaaccgcttg cgtttgtttg
     8341 acttggattc agttgattct tctattatta aagatggtat caactttgac aagatagata
     8401 tcgctcgcaa cttgactctc ttcctttacc cagatgatag tgaccgtcaa ggtgaattgc
     8461 tccgtatctt ccaacaatac ttcatggttt caaacggtgc gcaattgatc atcgacgaag
     8521 caatcgaaaa aggaagcaac ttgcatgacc ttgctgacta cgcagttgtc caaatcaacg
     8581 atactcaccc atcaatggtg attcctgaat tgattcgtct tttgactgca cgtggtatcg
     8641 agcttgacga agcaatctca attgttcgta gcatgactgc ctacactaac cacacaatcc
     8701 ttgctgaggc gcttgaaaaa tggcctcttg aattcttgca agaagtggtt cctcacttgg
     8761 taccaatcat cgaagaattg gaccgtcgtg tgaaggcaga gtacaaagat ccagctgttc
     8821 aaatcatcga tgagagcgga cgtgttcaca tggctcacat ggatatccac tacggataca
     8881 gtgttaacgg ggttgcagca ctccatactg aaatcttgaa aaattctgag ttgaaagcct
     8941 tctacgacat ttacccagaa aagttcaaca acaaaacaaa cggtatcact ttccgtcgtt
     9001 ggcttatgca tgctaaccca agattgtctc actacttgga tgagattctt ggagatggtt
     9061 ggcaccatga agcagatgag cttgaaaaac tgttgtctta tgaagacaaa gcagctgtca
     9121 aagaaaaatt ggaaagcatc aaggctcaca acaaacgtaa attggctcgt cacttgaaag
     9181 aacaccaagg tgtggaaatc aatccaaatt ctatctttga tatccaaatc aaacgtcttc
     9241 acgagtacaa acgccaacaa atgaacgctt tgtacgtgat ccacaaatac cttgacatca
     9301 aagctggtaa catccctgct cgtccaatca caatcttctt tggtggtaaa gcagctccag
     9361 cctacacaat cgctcaagac attatccatt taatcctttg catgtcagaa gttattgcta
     9421 acgatccagc agtagctcca cacttgcaag tagttatggt tgaaaactac aacgttactg
     9481 cagcaagttt ccttatccca gcatgtgata tttcagaaca aatctcactt gcttctaaag
     9541 aagcttcagg tactggtaac atgaaattca tgttgaacgg agctttgaca cttggtacta
     9601 tggacggtgc taacgtggaa atcgctgagt tggttggaga agaaaacatc tacatcttcg
     9661 gtgaagattc agaaactgtt atcgaccttt acgcaaaagc agcttacaaa tcaagcgaat
     9721 tctacgctcg tgaagctatc aaaccattgg ttgacttcat cgttagtgat gcagttcttg
     9781 cagctggaaa caaagagcgc ttggaacgtc tttacaatga attgatcaac aaagactggt
     9841 tcatgactct tcttgatttg gaagactaca tcaaagtcaa agagcaaatg cttgctgact
     9901 acgaagaccg tgacgcatgg ttggataaag tcatcgttaa catttctaaa gcaggattct
     9961 tctcatctga ccgtacaatc gctcagtata atgaagacat ctggcacttg aactaatact
    10021 cttcgaaaat ctcttcaaac cacgtcagct ttatctgcaa cctcaaagcg gtgctttgag
    10081 caacctgcgg ctagcttcct agtttgctct ttgattttca ttgagtataa gatacaaatt
    10141 tatactaata catcttgtaa aaaagcgagt ttcgattgaa attcgctttt ttaaatgctg
    10201 tggatttggg tcaatcttgt ctaaaaatag ggaaatccta gatacagtga aggctttaaa
    10261 tgctggtttt tgctgtcttc agccttatat tttttcgtag ttggttacct catatctctt
    10321 gtattcgctt acataaagta ttataatata attgtaggaa agaaggtgtt tttatgatat
    10381 acacacttaa attggtgttg tttattacct ttcttgtaat aagcttgtta cctgataaga
    10441 tttttggaaa aaataaaaaa atttggaaaa tagtttttgc aatattgacg gcagtggcag
    10501 cattgtcatt tatgtactaa gttattttaa gaatgtaggg aaataaaccc tacattcttt
    10561 ttagtttttt ctgttttcta aattctattt atccaagcgc ttcaacattt cttgcttctt
    10621 cgcttcaagt tctgcacgct tttcttcgat ttcggcatgt tttttctcga gttcagaaca
    10681 acttgcacca ttgctaaatt cttttcgcca tcaggagata gggtgagtcg acatgtctat
    10741 tactcaccca aagcagtcct acaaagcagg aattttctgt tacttttttg gaaatagtaa
    10801 cgtttataca gctttgacac ttcgtatcaa agcgccaaac acactccgag ggatttacag
    10861 aaagcagaaa aggaatgatc tggtataaga tcattccttt tctctctttt tctttaagta
    10921 attatataca atgtacgacg aagtcgtcat tgcaatgctg atccaccacc taaagggaac
    10981 tttaaacaac attgataaga taaagaatat aaacaacgaa aatacgttat acccaattaa
    11041 ttttattgta tatctcatga ttaaaagtta atccttccgt tgttaggaat ggcatcattt
    11101 ttatcccata attgtgctaa ataagtcccc ggtgataata aattcatagc ggattctaaa
    11161 gcaacatcat ttacaaacca attacctaga tatctagaaa ttgctgaacg aatagcactt
    11221 tttgctgcat gttttccttt tactttaatt agatttgcaa ggcctgcagt agttcctcct
    11281 aatgctaaag ctattgcagt atctaataga gcacccattt gattaactgt aataccttgc
    11341 caagctgctc taaatggaga gtatgtaggt gggattgtat aatcgccttg taattgtcgg
    11401 ttaattactt ctttgatcca ttgttgtgag acgtctggat gaaaagattg gatttcgttt
    11461 gcaagtgtat tgatttgttc ttctgttaga gaagtgacag gttgaagttc catatttgtt
    11521 tcaatttgtg atacttgttc agaagcgtat acagctgaaa cacttggaat cgctgataca
    11581 attaacacaa ttgacgtcaa aaaaaccgaa ataaatttca ttaatttgtt catgagcttt
    11641 tctccttttt atttgtatct gcttacattt tattatatac tgttattata gtcaagaaaa
    11701 atatgctatt atgttaaaaa aatattttta aaaatataaa tggacggatt tattttggat
    11761 tttatttgtt attttgacct gcctctatat tggtaaccat gatttgttta ctttcaatca
    11821 tcaagaattc tcttttcgtg gtagcgtttg gggtctggta ctggccttat atcacttatt
    11881 gttcattgat aagtttgtaa tttcgaatcg aaaataaaga ttagaactat gattgactgg
    11941 ctacttttaa tattgatttt ggaggaagat tttgtctcta ttatttatta ttttaaattt
    12001 atttattttg tataagatct attctttgag gcgggaaaaa tcgaaatact tgatttatac
    12061 ggcctatatc atatttgggg taaatgtagt atatggtatt caatggttat taagagaact
    12121 gatttcaact atttcccctt aatgtgtatg gaaactataa caaaacgcat aagattaagg
    12181 tttgtgtacc tgttcttatg cgtttttata atattgaaga ttttcggtaa gttttatacc
    12241 tttgggaagt ctagtttaga atgctttccc aaccaaaatc tctgcttcga tggtaatctc
    12301 tgtcagttgg ctccagtcaa tcttgctctg gtcaacgtga aagaggagag gagtcatact
    12361 gagtagggct tggagttgtt ctgctgtgat agtcttagtc agagaggcag tttgactaga
    12421 taggatggta aagtgttcct ggaaatgctc cttgatatct tggttagaat actccttgtt
    12481 tgtcagctgg tcctgtactc tttgacggat ttctttgagg tgattttcag ttgggataac
    12541 ctttatcaag ataccgtctt tggataaaac gcgacgaaat tctccatagt tggcaggtga
    12601 gaagatatca agcagaatat ccatgttagc gtcttttata ggaagtcgtg ccaagtcgcc
    12661 aacaaaccaa ttgactgccc agttgggttc acttttagca gcgatttgga ctgaatcttt
    12721 ggagatgtca aaggcataga aagttttttc agagtgactt tcttgtagtt tgcgagaata
    12781 gaatccttca ccacaaccga tatccaaaat tgttgtggta gtttttgagc ttgcaagcaa
    12841 gtcagataca gcatctaaga tagcttggta aaagccggct tctaggattt gttgacggtt
    12901 ttgaaaattt tccttgttat agttagcaga ttgcttgatt tgaggtgcta gattgacata
    12961 gccaaatttc gccaagtcaa aagaatgacg gttgcagcac ttgaaattag tctctaacag
    13021 agtcagattt tcttgacaga taggacaggc aaaggcagtc gcagaagcaa aacgctgaag
    13081 tttgggcttg agatttgtat tcatagttta agtgtatcaa aagaggcaaa tgaaagcaac
    13141 tttaggaata agtagatggg agattcagta gaaataaaac taattctcca atttatagaa
    13201 tgaaattgct tttatatcta aattgctata taataatgat aaggaggaaa taagtatgtt
    13261 aaaagaagta ttaaccgttg caaaagttgc gaaaaaatct tcattatttt tgggtggtgt
    13321 cgcatttggt acccttggtt tgaaaatctt agcaagtaag gaagctaaaa aaggttattc
    13381 taaagctttg gctaaggctt acaagttgaa agacgagcta gatgcatctg tttctgttgt
    13441 gaagcaacat ggagacgatg tcttgcaaga tgccaaatat ttgtacgagc aagagaaaaa
    13501 agaagagcaa ttagatagcc ttataggtga ataatatgtc ttttaaagtg ctacatagag
    13561 gataccaaca tatccgacta tcatcttctt tttcacttac cttggatatt caagactatc
    13621 ttcgttcctt ggcgagagat gaaaagggga ttgagtctat ccagttttac atggatcaac
    13681 agcactttac tctacgcata aaagaaggct tttctgtatt agataatgca gaagcctttt
    13741 taaaaagaat tgataaaggg aaagtttctg agttgatgac tcttcccatt cgtagagaag
    13801 agagtgctta ttctattgtt tcaggtgcag cggttaagcg tgtacttttt cgtagttttg
    13861 tgccgtatcc tattcgctat atatggactt gttatcaggc tttgggttat attagagaag
    13921 cctatcaaac actagcgcgt aaggaactaa cgatggaagt cttggactgt tcggctattt
    13981 tattgtcttt gtttatgaac caatccaaga cagctagcaa tatcatgttt atgcttgatt
    14041 tggggaatca tttagatcag tggtccttga aaaaaactgc aacagattta gaacagagtc
    14101 ttcttgcaaa agagagcgat gtattcctag tacagggcga tacggttgtt agtatcaaga
    14161 gttccgatgt tcaaatagga gatgtcttga tcttatctca aggaaatgaa attctgtttg
    14221 atggacaagt agtttcaggt ttaggtatgg tcaacgaaag ttccttgaca ggagagagtt
    14281 ttccagttga aaaaagagag tctgatttgg tttgtgcaaa tacagtatta gaaactggag
    14341 agttacgcat ttgtgtaaca gataatcaga tgaacagccg tcttttacag ctgattgagt
    14401 tgatgaagaa atctgaagaa aacaagaaaa cgaaacaacg ctatttcatc aagatggcgg
    14461 ataaagtcgt caaatataat ttcttggggg ctgggctgac ttacctattg acaggttctt
    14521 tttctaaggc tatttctttc ctattggtcg atttctcctg cgctttgaaa atctctactc
    14581 ctgtagctta tttgacagtt atcaaggaag ggttgaaccg tgaaatggtg attaaggatg
    14641 gagatgttct ggagaaatat ctggaagttg atactttctt gtttgataag acaggaacaa
    14701 tcacaactag ttatcctata gttgaaaagg tgttaccttt tggagactat agtgaggaag
    14761 atattctcag aatcagtgcc tgtcttgagg aacacattta tcatcctatt gctaatgcca
    14821 tcgtcaagca agctgagata gagggaattg aacatgagga aatgcatggg aaactccaat
    14881 atatcgcaag caaggggatc aaatctcata tagatggcca accagttctt attgggaatt
    14941 atgtcttgat gcaggatgag cagattcata tcagttcaga acaaaatgct ttaattgaag
    15001 agtacaagag tcactacaat ctcttattct tggcttatca aaatgaattg attggaatgt
    15061 tctgcattca tactcctttg agaaaagaag caaaaacagc cttggataaa cttaaggcac
    15121 aggggaaaaa attgattctg gcaacaggag acaccttgac taggacagag gaattagtca
    15181 aagatttgcc ctttgatcag gtctatacag acttgaaacc tgatgggaaa tttgagttag
    15241 tagagaaact gcagaaagca ggtcacacta ttttgatggt tggagatgga ttgaatgact
    15301 cagcggcttt aactctatca gatatcggtg tggtgatgaa tgagagtgca gatatttcta
    15361 agcagatgag tgatatctta ttgttagata atcgtttgga tttcttccaa gagttggatt
    15421 cgttatcatc atctttgcaa acactcatca agaaaaatat tcaagatacc gttgtcgtaa
    15481 atagtagttt gattggcttc ggcttattta attggctcag tccttcaaat ctctctatct
    15541 tacataatct aacaaccttg cgcattgtcc tgcgtagcct gtctattaaa aatagataga
    15601 tgagagttat taacagcaaa aaggagttac ctttctcgag gctaactcct ttgtttatag
    15661 ataaatgttg aatagtttag taagtcaata caaagtattt tttcttccca cgacggataa
    15721 cagtcagttc attctctaac ttatcagcgt cactcaagac atagtcaagc tcttggatgc
    15781 ggtcgccgtt tacgtagatg gctccgtttt ggacgtcttc acgggcttgg cgttttgagt
    15841 taactatacc agatgagacg agcagttcca cgatattgtt gttttcgtct gcctgtactt
    15901 ggtagtttgg cacaccacga agtccttgtt tgagctcttt gacagaaagg tttttgatgt
    15961 ttcctgcaaa gagttgctca gtgatgttaa gtgcttcttt gtaggcttct tctccgtgaa
    16021 caagtgtaac aacttcacga gccaagactt tttgagccaa gcgttcgtgt ggcgctgctt
    16081 caaattgttt acgaatatct tcaatctcat caagtgacaa gaaagtaaag attttcaaga
    16141 agcgaacagc gtcagcgtcc atcacgttca tccagaattg gtacatttcg tatggagaag
    16201 tcttttcggg attgagccag acggcatttc cttctgattt accaaatttc ttaccagttg
    16261 catctgtgat tagtggaaca gtgataacgt gaccagtctt gtccgcttta cgacgaagca
    16321 attcggtacc agctgtcata tttccccact ggtcagaacc accgatttga agagtgacat
    16381 tatggtcttg gttaaggacg aagaagtcgt acccttgcat gatttggtaa gcgaactcag
    16441 tgtaagaaat tcctgtttcg attcgttttt ttacagattc cttactcatc atgtagttga
    16501 ccgtgaagta ttttccaata tcacggagga agtcaatgaa gctgatgctg ccaaaccagt
    16561 cgtagttgtt gaccatgaca gccttgtttt cgccattttc aaagtcaaga aaacgagaaa
    16621 gttgtccttg gatagacttg acccagccat ctactgtgtc ttttgtttgg agactacgtt
    16681 cagcatcttt gaaggacgga tctccgatga gacctgtagc accgccaacg agcgcataag
    16741 gtttgtgacc tgctagttgc aagcgacgac ttgtcaagat tgcgacaagg tggcctaggt
    16801 gaaggctgtc agcagttgga tcgtagccag tataataaga aacttgacct tcttctaggg
    16861 ctttacgcaa agcttcttca tcagtcgttt gaaatatcaa accacgatct tttagctcat
    16921 caaaaatgtg catgtgtctt ttctcctttt taaaattatt gtttctacct attgtatcac
    16981 aaacttgggc aatagcctag cagaataggg aagaaagtgg ctattttatt gaaaatttcc
    17041 cttttgtggt ataatagata gagtgaggaa atccatgcaa aatcaattaa atgaattaaa
    17101 acgaaaaatg ctggaatttt tccagcaaaa acaaaaaaat aaaaaatcag ctagacctgg
    17161 caagaaaggt tcaagtacca aaaaatctaa aaccttagat aagtcagcca ttttcccagc
    17221 tattttactg agtataaaag ccttatttaa cttactcttt gtactcggtt ttctaggagg
    17281 aatgttggga gctgggattg ctttggggta cggagtggcc ttatttgaca aggttcgggt
    17341 gcctcagaca gaagaattgg tgaatcaggt caaggacatc tcttctattt cagagattac
    17401 ctattcggac gggacggtga ttgcttccat agagagtgat ttgttgcgca cttctatctc
    17461 atctgagcaa atttcggaaa atctgaagaa ggctatcatt gcgacagaag atgaacactt
    17521 taaagaacat aagggtgtag tacccaaggc ggtgattcgt gcgaccttgg ggaaatttgt
    17581 aggtttgggt tcctctagtg ggggttcaac cttgacccag caactaatta aacagcaggt
    17641 ggttggggat gcgccgacct tggctcgtaa ggcggcagag attgtggatg ctcttgcctt
    17701 ggaacgcgcc atgaataaag atgagatttt aacgacctat ctcaatgtgg ctccctttgg
    17761 ccgaaataat aagggacaga atattgcagg ggctcggcaa gcagctgagg gaattttcgg
    17821 tgtagatgcc agtcagttga ctgttcctca agcagcattt ttagcaggac ttccacagag
    17881 tcccattact tactctcctt atgaaaatac tggggagttg aagagtgatg aagacctaga
    17941 aattggctta agacgggcta aggcagttct ttacagtatg tatcgtacag gtgcattaag
    18001 caaagacgag tattctcagt acaaggatta tgaccttaaa caggactttt taccatcggg
    18061 cacggttaca ggaatttcac gagactattt atactttaca actttggcag aagctcaaga
    18121 acgtatgtat gactatctag ctcagagaga caatgtctcc gctaaggagt tgaaaaatga
    18181 ggcaactcag aagttttatc gagatttggc agccaaggaa attgaaaatg gtggttataa
    18241 gattactact accatagatc agaaaattca ttctgccatg caaagtgcgg ttgctgatta
    18301 tggctatctt ttagacgatg gaacaggtcg tgtagaagta gggaatgtct tgatggacaa
    18361 ccaaacaggt gctattctag gctttgtagg tggtcgtaat tatcaagaaa atcaaaataa
    18421 tcatgccttt gataccaaac gttcgccagc ttctactacc aagcccttgc tggcctacgg
    18481 tattgctatt gaccagggct tgatgggaag tgaaacgatt ctatctaact atccaacaaa
    18541 ctttgctaat ggcaatccga ttatgtatgc taatagcaag ggaacaggaa tgatgacctt
    18601 gggagaagct ctgaactatt catggaatat ccctgcttac tggacctatc gtatgctccg
    18661 tgaaaagggt gttgatgtca agggttatat ggaaaagatg ggttacgaga ttcctgagta
    18721 cggtattgag agcttgccaa tgggtggtgg tattgaagtc acagttgccc agcataccaa
    18781 tggctatcag accttagcta ataatggagt ttatcatcag aagcatgtga tttcaaagat
    18841 tgaagcagca gatggtagag tggtgtatga gtatcaggat aaaccggttc aagtctattc
    18901 aaaagctact gcgacgatta tgcagggatt gctacgagaa gttctatcct ctcgtgtgac
    18961 aacaaccttc aagtctaacc tgacttcttt aaatcctact ctggctaatg cagattggat
    19021 tgggaagact ggtacaacca accaagacga aaatatgtgg ctcatgcttt cgacacctag
    19081 attaacccta ggtggctgga ttgggcatga tgataatcat tcattgtcac gtagagcagg
    19141 ttattctaat aactctaatt acatggctca tctagtaaat gcgattcagc aagcttcccc
    19201 aagcatttgg gggaacgagc gctttgcttt agatcctagt gtagtgaaat cggaagtctt
    19261 gaaatcaaca ggtcaaaaac cagggaaggt ttctgttgaa ggaaaagaag tagaggtcac
    19321 aggttcgact gttaccagct attgggctaa taagtcagga gcgccagcga caagttatcg
    19381 ctttgctatt ggcggaagtg atgcggatta tcagaatgct tggtctagta ttgtggggag
    19441 tctaccaact ccatccagct ccagcagttc aagtagtagt tctagcgata gcagtaactc
    19501 aagtactaca cgaccttctt cttcaagggc gagacgataa ttctctaaat gaagtggcca
    19561 atcaatggat tgccactttt ttcttttcgt gttacaataa gggtatgaat cagtatcaga
    19621 aaaagattgt taacggaaaa atttattcgc tcctatccgg cttaatatgg ggaatctgtg
    19681 gaattttagg agagtacttc tttactcatt atcaggtgtc ttcgggctgg attacctcta
    19741 tgcgtttgac actggcaggg agtcttgtac tcatttggtc tgcaatacaa ttaaaatcgc
    19801 aagtgctaga tatttggcga gacaagaaaa attacctgcc ctttttagcc tatgctattt
    19861 tggggatttt ttcagttcag tattttttct atctctgtgt agaatactca aatgctacga
    19921 cagcaactat tttacagttt attagccctg tctttatcct cttttacaat cgcttggttt
    19981 atcaaaaacg agcgtcaaaa agcgctgttt tctatgtttt ggttgccatg ctgggtgttt
    20041 gcttgatggc gacaaaggga gatctctctc agttatccat gacgccgcta gctcttataa
    20101 caggtttgct gagtgccatg ggtgttatgt ttaatgttat cttgccccaa ccttttgcta
    20161 agcgttatgg ttttgttcct acggttgggt gggggatgat tttggcaggt ttgtttagca
    20221 atgtcctctc gccggtttat cagctttcct ttactcttga tatttggagt atcttgattt
    20281 gcctcattat cgctttcttt ggaacggctt ttgctttttt catttccatg aaggctgtgt
    20341 ccttggtttc tcctttggtg gttgccgtta tcagtgccag tgaacctctc tcttctgctc
    20401 tcttgagtgt tttgttctta ggattagtag tggattggtc cctccttcta gctatagcct
    20461 tgattatttt acccatgata tttttgtcta tagaagaagc gaaagaaagt agataaaaag
    20521 tcttttctta attctaaaag tgtgctatac tagaatagtc aataaaacac ggggagatag
    20581 ttgtgaagaa tgtttttagg ttgtatcggt aggggcttgc ttttaccgac agcacgtttt
    20641 atctcacaac cctaaaaaat catacctaaa aacagacaaa aaggtttcaa atttgaggcc
    20701 ttttttggta gaataggtat cattataacg aaccaggagg cacctatgac tgctacaaaa
    20761 atgaacgctc aagaaattat ccaatttatc gccaatgctg aaaagaaaac cagtgtcaaa
    20821 gtaacctttg aggggcaact cgcaactgct gtgcctagct ctgttgtcaa actaggaaat
    20881 gtcctattcg gagactggaa ggacgtggct ccgcttcttg aaggtttggt agaaaatcaa
    20941 gattatgttg tcgagcaaga tgctcgtaat tctgcagttc ctttgctaga taagcgtgct
    21001 atcaacgctc gtatcgagcc aggtgctatt atccgtgacc aggtggaaat tggtgacaat
    21061 gctgttatca tgatgggagc tgttatcaat atcggtgctg aaatcggtgc tggaaccatg
    21121 attgacatgg gtgccatcct tggtggccgt gccatcgttg gaaaaaatag ccacgttggt
    21181 gcaggtgcag ttttggcagg tgtgattgag ccagctagtg ctgaaccagt ccgtgtcgga
    21241 gacaatgttc ttatcggtgc taatgcagtg gttatcgaag gagtccaaat cggtagtggt
    21301 tcagttgtcg cagcaggagc tattgttacc caagatgtcc cagaaaacgt ggtagtagca
    21361 ggtgttccag ctcgtattat caaagaaatt gatgcccaaa ctcaacaaaa aacagcgcta
    21421 gaggatgcgc ttcgtacctt gtaattgtaa aagtaaaaaa gaggcggaac cctttttcca
    21481 gcctctttct gctatatcgg aggacagata gatgttagat ttgattcaga ctagacgaga
    21541 tttacaccag ataccagaga ttggcttgga ggagttcaag actcaggctt atttgctgga
    21601 tgtgattgag aaattgacta cgggcaagga ttttgttcaa attcgtactt ggcggacagg
    21661 gattttggtc tacctgcagg gaagtcagcc ggagcgaacc attggttggc ggacagatat
    21721 tgatggcctg cctatcgtcg aacaaacagg tctacctttt gcttctcaac accaaggtcg
    21781 catgcatgcc tgtggccatg attttcatat gaccattgcc ttaggctgtc ttgagcgcgc
    21841 ccttgaggag caacctaaaa ataatctgct ctttctattt cagcctgctg aagaaaatga
    21901 agctggtggt atgctcatgt atgaggctgg tgcttttgga gattggttgc caaaccaatt
    21961 ctatggtctc catgttcgtc cagatttgaa agtcggccag attgcgacta atactcatac
    22021 actctttgca ggaacttgcg aggtgaagat ccgtttcaaa ggcaaaggtg gccacgcagc
    22081 ttttcctcat gaagccaatg acgccttggt ggcggctagt tactttgtga cccaagtgca
    22141 gtcagttgtt agccgcaatg tcaacccaat cgagggagca gtggtgacct tcggcgtttt
    22201 tcaagctgga accaccaaca atgtcatcac agacacagct tttttacatg gaactattcg
    22261 tgccttgaca caggacatga gtctcttggt gcaaaagagg gtaaaaacag ttgcagaagg
    22321 ggttgcagct gcctttgata tggaagtcga agtggaactc aaacaaggtg gatacctacc
    22381 tgttgagaac aatccagcct tggcgtgtga actgatggac ttctttgacg aaaaagacgg
    22441 aatcgagttg attgatatcg aacctgctat gacaggcgag gactttggtt atctcctttc
    22501 aaaggttgat ggcgtgatgt tttggctagg tatcgatagt ccctacgctc ttcatcaccc
    22561 tcaaatgagt cctaaggaag aagtcttagc tattggggtg gctgcggtgt ctagtttcct
    22621 gaaaaagaag gcagcagaat agagggcttg tctatgaaat cggaattacg caagcaagtc
    22681 ttgcatgaaa tgaaggctat atctcaagag caaaaacagg ctatagacca agctttaacc
    22741 gagcggcttt tacaccatcc cttctaccaa gaagccaagg tcatcgcaac ctacctctct
    22801 ttttctcatg agtttcaaac gcgggaactg attgagcagg cgctgaagga cggcaagaag
    22861 gttttaatgc ccaaaactta tcccaagggg cgcatggact ttgtggtcta tgatccgcaa
    22921 cagttggtaa aaacttcctt tgccttactg gagccacagg gagatgtgga agtggtggat
    22981 gcatctcaga ttgatttgat tcatgttcct ggtctggctt ttacgacgaa aggatatcgg
    23041 ataggatacg gtggaggcta ttatgaccgc tatctggaac atttttctgg tcatactttg
    23101 agtacggttc atccttgtca aattcaggac tttatacctg aaaaccatga tattcctgtt
    23161 caggaggtat taattgatga aggaaatctt tgatagacgt taccctgtga cgagtttctt
    23221 cctcttagtg acggccttgg tatttttact aatgttggtc actgcaggcg gaaactttga
    23281 cagggcagat acattatttc gatttggagc catgtatggg ccagctattc gcctctttcc
    23341 cgagcaggtt tggcgtctct tgtctgccat ttttgttcat attgggtggg aacatttcat
    23401 tgttaatatg ctttcacttt attatcttgg aaggcaggta gaggagattt tcggctctaa
    23461 gcagttcttt tttctctatc tcttatcagg aatgatgggc aatctctttg tttttgtatt
    23521 tagtcctaaa tccttagcag caggcgcctc tacctctctt tatgggctat ttgccgcgat
    23581 tattgttctt cgctatgcaa ctcgcaatcc ttatatccaa cagctagggc aatcctatct
    23641 gacacttttt gtggttaaca ttattggaag tgttctgatt ccaggaatca gcctagcagg
    23701 ccatatcggt ggtgcagttg gtggcgcatt tctagcagtt atctttccag ttagaggaga
    23761 aaaacggatg tataacacca gccagagatt aggagcggta gtcttgttcg taggactcgc
    23821 cattttgctt ttctacaagg gaatgggatt gtgacgacta atactcaatg aaaatcaaag
    23881 agcaaactag gaagctagcc gcaggttgct caaagcactg ctttgaggtt gtagatag
//
LOCUS       DAVBOD010000025        23836 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 640-05
            SAMEA1012484-rid20186543.denovo.025, whole genome shotgun sequence.
ACCESSION   DAVBOD010000025 DAVBOD010000000
VERSION     DAVBOD010000025.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012484
            Sequence Read Archive: ERR059358
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 23836)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23836)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979948.1
            Genome Coverage       :: 595x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:03:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,266
            CDSs (total)                      :: 2,219
            Genes (coding)                    :: 2,091
            CDSs (with protein)               :: 2,091
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 71 of 128
            Pseudo Genes (incomplete)         :: 50 of 128
            Pseudo Genes (internal stop)      :: 33 of 128
            Pseudo Genes (multiple problems)  :: 22 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23836
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012484-rid20186543.denovo.025"
                     /strain="NIG 640-05"
                     /db_xref="taxon:1313"
     gene            complement(98..2356)
                     /locus_tag="VQ862_001132"
     CDS             complement(98..2356)
                     /locus_tag="VQ862_001132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HET3115489.1"
                     /translation="MLCQNCKINDSTIHLYTNLNGKQKQIDLCQNCYKIIKTDPNNSL
                     FKGMTDLNNRDFDPFGDFFNDLNNFRPSSNTPPIPPTQSGGGYGGNGGYGSQNRGSAQ
                     TPPPSQEKGLLEEFGINVTEIARRGDIDPVIGRDDEIIRVIEILNRRTKNNPVLIGEP
                     GVGKTAVVEGLAQKIVDGDVPHKLQGKQVIRLDVVSLVQGTGIRGQFEERMQKLMEEI
                     RKREDIILFIDEIHEIVGAGSASDGNMDAGNILKPALARGELQLVGATTLNEYRIIEK
                     DAALERRMQPVKVDEPTVDETITILKGIQKKYEDYHHVQYTDAAIEAAATLSNRYIQD
                     RFLPDKAIDLLDEAGSKMNLTLNFVDPKVIDQRLIEAENLKSQATREEDFEKAAYFRD
                     QIAKYKEMQKKKITDQDTPIISEKTIEHIIEQKTNIPVGDLKEKEQSQLIHLAEDLKS
                     HVIGQDDAVDKIAKAIRRNRVGLGTPNRPIGSFLFVGPTGVGKTELSKQLAIELFGSA
                     DSMIRFDMSEYMEKHSVAKLVGAPPGYVGYDEAGQLTEKVRHNPYSLILLDEVEKAHP
                     DVMHMFLQVLDDGRLTDGQGRTVSFKDAIIIMTSNAGTGKTEASVGFGAAREGRTNSV
                     LGELGNFFSPEFMNRFDGIIEFKALSKDNLLQIVELMLADVNKRLSSNNIRLDVTDKV
                     KEKLVDLGYDPKMGARPLRRTIQDYIEDTITDYYLENPSEKDLKAVMTSKGNIQIKSA
                     KKAEVKSSEKEK"
     gene            complement(2585..2815)
                     /locus_tag="VQ862_001133"
     CDS             complement(2585..2815)
                     /locus_tag="VQ862_001133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005592360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YkuJ family protein"
                     /protein_id="HET3115490.1"
                     /translation="MESHLVRIINRLEAMANDGGNLKRNFEREGVVVAEVAYSHDEEN
                     GPIFTLRDVEDRETYTFDSIDLIAMEIYELLY"
     gene            3005..3688
                     /locus_tag="VQ862_001134"
     CDS             3005..3688
                     /locus_tag="VQ862_001134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001011621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HET3115491.1"
                     /translation="MNFSFLPKYLPYFNYGAVVTILISICVIFLGTILGVVLAFGQRS
                     KFKPLVWLANLYVWIFRGTPMMVQIMIAFALMHINAPTIQIGILGVDFSRLIPGILII
                     SMNSGAYVSETVRAGINAVPKGQLEAAYSLGIRPKNAMRYVILPQAIKNILPALGNEF
                     ITIIKDSSLLSAIGVMELWNGATTVSTTTYLPLTPLLFAAFYYLIMTSILTVALKAFE
                     KHMGQGDKK"
     gene            3688..4422
                     /locus_tag="VQ862_001135"
     CDS             3688..4422
                     /locus_tag="VQ862_001135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000140960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HET3115492.1"
                     /translation="MTETLIKIENLHKSFGKNEVLKGINLEIKRGEVVVIIGPSGSGK
                     STLLRSMNLLEEATKGKVIFEGVDITDKKNDLFAMREKMGMVFQQFNLFPNMTVIENI
                     TLSPIKTKGESREVAEKRAQELLEKVGLPDKADAYPQSLSGGQQQRIAIARGLAMEPD
                     VLLFDEPTSALDPEMVGEVLAVMQDLAKSGMTMVIVTHEMGFAREVADRVIFMADGVV
                     VEDGTPEQIFEQTQEQRTKDFLSKVL"
     gene            4576..5433
                     /locus_tag="VQ862_001136"
     CDS             4576..5433
                     /locus_tag="VQ862_001136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000192112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional methylenetetrahydrofolate
                     dehydrogenase/methenyltetrahydrofolate cyclohydrolase"
                     /protein_id="HET3115493.1"
                     /translation="MTQIIDGKALAAKLQGQLAEKTAKLKEETALVPGLVVILVGDNP
                     ASQVYVRNKERSALAAGSRSEVVRVPETITQEELLDLIAKYNQDPAWHGILVQLPLPK
                     HIDEEAVLLAIDPEKDVDGFHPLNMGRLWSGHPVMIPSTPAGIMEMFHEYGIDLEGKN
                     AVVIGRSNIVGKPMAQLLLAKNATVTLAHSRTHNLAKVAAKADILVVAIGRAKFVTAD
                     FVKPGAVVIDVGMNRDENGKLCGDVDYEAVAPLASHITPVPGGVGPMTITMLMEQTYQ
                     AALRTLDRK"
     gene            5575..6447
                     /locus_tag="VQ862_001137"
     CDS             5575..6447
                     /locus_tag="VQ862_001137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000864675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-hydrate dehydratase"
                     /protein_id="HET3115494.1"
                     /translation="MKVINQTLLEKVIIERSRSSHKGDYGRLLLLGGTYPYGGAIIMA
                     ALAAVKSGAGLVTVGTDRENIPALHSHLPEPMAFSLQDQQLLKEQLEKAEVILLGPGL
                     RDDASGENLVKQVFVNLSQNQILIVDGGALTILARTSLSFPSSQLILTPHQKEWEKLS
                     GITIEKQKEDATASVLTSFPQGTILVEKGPATRIWEVGQSDYYQLQVGGPYQATGGMG
                     DTLAGMIAGFVGQFRQASLYERVAVATHLHSAIAQELSQENYVVLPTEISRYLPKIMK
                     IICQQDRVSKDKLV"
     gene            6729..7412
                     /gene="rpiA"
                     /locus_tag="VQ862_001138"
     CDS             6729..7412
                     /gene="rpiA"
                     /locus_tag="VQ862_001138"
                     /EC_number="5.3.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000429260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-5-phosphate isomerase RpiA"
                     /protein_id="HET3115495.1"
                     /translation="MENLKKMAGIKAAEFVSDGMVVGLGTGSTAYYFVEEIGRRIKEE
                     GLQITAVTTSSVTTKQAEGLNIPLKSIDQVDFVDVTVDGADEVDSQFNGIKGGGGALL
                     MEKVVATPSKEYIWVVDESKLVEKLGAFKLPVEVVQYGAEQVFRHFERAGYKPSFREK
                     DGQRFVTDMQNFIIDLALDVIENPIAFGQELDHVVGVVEHGLFNQMVDKVIVAGRDGV
                     QISTSKKGK"
     gene            7426..8637
                     /locus_tag="VQ862_001139"
     CDS             7426..8637
                     /locus_tag="VQ862_001139"
                     /EC_number="5.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopentomutase"
                     /protein_id="HET3115496.1"
                     /translation="MSKFNRIHLVVLDSVGIGAAPDANNFVNAGVPDGASDTLGHISK
                     TVGLNVPNMAKIGLGNIPRETPLKTVAAESNPTGYATKLEEVSLGKDTMTGHWEIMGL
                     NITEPFDTFWNGFPEEILTKIEEFSGRKVIREANKPYSGTAVIDDFGPRQMETGELII
                     YTSADPVLQIAAHEDIIPLDELYRICEYARSITLERPALLGRIIARPYVGEPGNFTRT
                     ANRRDLAVSPFSPTVLDKLNEAGIDTYAVGKINDIFNGAGINHDMGHNKSNSHGIDTL
                     LKTMGLAEFEKGFSFTNLVDFDALYGHRRNAHGYRDCLHEFDERLPEIIAAMRENDLL
                     LITADHGNDPTYAGTDHTREYIPLLAYSPAFKGNGLIPVGHFADISATVADNFGVETA
                     MIGESFLDKLV"
     gene            8639..9181
                     /locus_tag="VQ862_001140"
                     /pseudo
     CDS             8639..9181
                     /locus_tag="VQ862_001140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398095.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1697 domain-containing protein"
     gene            9197..10006
                     /locus_tag="VQ862_001141"
     CDS             9197..10006
                     /locus_tag="VQ862_001141"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HET3115497.1"
                     /translation="MTFLNKIHETATFLKEKGIAAPEFGLILGSGLGELAEEIENPVV
                     VDYAEIPNWGRSTVVGHAGKLVYGELAGRKVLALQGRFHFYEGNPLEVVTFPVRVMKV
                     LGCEGVIVTNAAGGIGFGPGTLMAISDHINMTGQNPLMGENLDDFGPRFPDMSRAYTP
                     EYRATAHEVAKKLNIKLDEGVYIGVTGPTYETPAEIRSYKTLGADAVGMSTVPEVIVA
                     AHSGLKVLGISSITNFAAGFQEELNHEEVVEVTERVKGDFKGLLKAILAEL"
     gene            10482..11213
                     /locus_tag="VQ862_001142"
     CDS             10482..11213
                     /locus_tag="VQ862_001142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011681781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3115498.1"
                     /translation="MLDSKEELKESENDAPKLETPLREEPRLAPQTLPEASEVLENKR
                     EESKVEITEPAQADDIRKVVGELAKDISITKLYMTGHSLGCYLAQIAEVEAYQKYPDF
                     YNHVLRKVTTFSAPKVITSRTVWNAKNGFWDVGLESRKLAVSGKIKHYVVDNDNVVTP
                     LIHNDRDIVTFTGNSRFKHRSRGYFESPMNDIPNFNIGKQATLDKHGYRDPKLDKVRF
                     FKKQALPRSSSQPSAEPMENIALGK"
     gene            11259..11462
                     /locus_tag="VQ862_001143"
     CDS             11259..11462
                     /locus_tag="VQ862_001143"
                     /inference="COORDINATES: protein motif:HMM:NF012956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="discoidin domain-containing protein"
                     /protein_id="HET3115499.1"
                     /translation="MDGKVDGNYGHNSVTHTNFQSKPWWQVDLAKEETIRQINIYNRT
                     DTAQDRLANFDVILLDSSGKEIE"
     gene            11487..11999
                     /locus_tag="VQ862_001144"
     CDS             11487..11999
                     /locus_tag="VQ862_001144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001275913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin"
                     /protein_id="HET3115500.1"
                     /translation="MSAQITINHKKARYVRIELEGYNALSLAEVEVFRFIATNGETAI
                     QVSKSVQPISQTPVKDKTLTIQHSGAYIARYSITWEEVTVDKDGNQVVRSHSWEGNGR
                     NQTAGFVLNLPIKENMRNLRVKIEKKTGLLWNRWQTIYENRPILAQPHRKITHWGTTL
                     NSKVSDDDVL"
     gene            12657..13367
                     /gene="deoD"
                     /locus_tag="VQ862_001145"
     CDS             12657..13367
                     /gene="deoD"
                     /locus_tag="VQ862_001145"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HET3115501.1"
                     /translation="MSIHIAAQQGEIADKILLPGDPLRAKFIAENFLGDAVCFNEVRN
                     MFGYTGTYKGHRVSVMGTGMGMPSISIYARELIVDYGVKKLIRVGTAGSLNEEVHVRE
                     LVLAQAAATNSNIVRNDWPQYDFPQIASFDLLDKAYHIAKELGMTTHVGNVLSSDVFY
                     SNYFEKNIELGKWGVKAVEMEAAALYYLAAQYHVDALAIMTISDSLVNPDEDTTAEER
                     QNTFTDMMKVGLETLIAE"
     gene            complement(13390..13914)
                     /locus_tag="VQ862_001146"
     CDS             complement(13390..13914)
                     /locus_tag="VQ862_001146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000684222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topology modulation protein"
                     /protein_id="HET3115502.1"
                     /translation="MKITIIGYSGSGKSTLAEKLSNYYSIPKLHMDTLQFQPGWQDSD
                     CEWMLTEIKNFLTKHKAWVIDGNYSWCYYQERMQEADQIIFLNFLPLTCLFRAFKRYL
                     KYRGKVRESMAADCPERFDWEFIRWILWDGRSKTQKENYQKLCQEYSHKVTILRNQRE
                     LDQFLDKKRKSYNS"
     gene            complement(13967..14203)
                     /locus_tag="VQ862_001147"
     CDS             complement(13967..14203)
                     /locus_tag="VQ862_001147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001274003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S20"
                     /protein_id="HET3115503.1"
                     /translation="MANIKSAIKRAELNVKQNEKNSAQKSAMRTAIKAFEANPSEELF
                     RAASSAIDKAETKGLIHKNKASRDKARLSAKLAK"
     gene            complement(14271..15191)
                     /locus_tag="VQ862_001148"
     CDS             complement(14271..15191)
                     /locus_tag="VQ862_001148"
                     /EC_number="2.7.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I pantothenate kinase"
                     /protein_id="HET3115504.1"
                     /translation="MTNEFLHFEKISRQTWQSLHRKTTPPLTEEELESIKSFNDQISL
                     QDVTDIYLPLAHLIQIYKRTKEDLAFSKGIFLQRESKSQPFIIGVSGSVAVGKSTTSR
                     LLQILLSRTFTDATVELVTTDGFLYPNQTLIEQGILNRKGFPESYDMEALLNFLDRIK
                     NGQDVDIPVYSHEVYDIVPEEKQSVKAADFVIVEGINVFQNPQNDRLYITDFFDFSIY
                     VDAGVDDIESWYLDRFLKMLSLAQNDPDSYYYRFTQMPIGEVEAFAHQVWTSINLTNL
                     QNYIEPTRNRAEVILHKSKNHEIDEIYLKK"
     gene            15389..15793
                     /locus_tag="VQ862_001149"
     CDS             15389..15793
                     /locus_tag="VQ862_001149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3115505.1"
                     /translation="MKILKRYILELCFILSFALPFIKGANADNGICFVETYYGFTFLM
                     EHAIVTAVFIYSFLIAFLLKKRWAKWIAAGSYCFLVLWIATEGYFFRMSLEDLIRLWT
                     SLEILTQTYQLGFYLNILLGILLIIKYFKVKQ"
     gene            16009..16590
                     /locus_tag="VQ862_001150"
     CDS             16009..16590
                     /locus_tag="VQ862_001150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000289981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HET3115506.1"
                     /translation="MYYAENPDAAHDIHELRVELLGQKMTFLTDAGVFSKKIVDFGSQ
                     LLLKCLEVNQGETVLDVGCGYGPLGLSLAKAYGVQATMVDINTRALDLARRNAEKNNA
                     KATIFQSNIYEQVEGHFDHVISNPPIRAGKQVVHEIIEKSKDFLETGGDLTIVIQKKQ
                     GAPSAKSKMEDVFGNCEILKKDKGYYILRSVKE"
     gene            16587..17864
                     /locus_tag="VQ862_001151"
     CDS             16587..17864
                     /locus_tag="VQ862_001151"
                     /EC_number="2.4.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001202959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine-nucleoside phosphorylase"
                     /protein_id="HET3115507.1"
                     /translation="MRAVDLIQKKRDGQELTSSEIEWLVEGYVSGTVPDYQMSAFAMA
                     VYFKGMTTREISDLTMNMVKTGQEFDLSAIDGVKVDKHSTGGVGDKVTLILAPLVASF
                     GVPVAKMSGRGLGHTGGTIDKLESIKGYQVERSQEDFIRQVQDIGVSVIGQSDQLVKA
                     DKLLYALRDVTATVDTIPLIASSVMSKKIAAGADAILLDVTVGEGAFMKTVDEARELA
                     QTMVDLGKVVGRKTVAVITDMSQPLGRAIGNRLEILEALEILQGQGRQDITHFICELA
                     QIMLGLANVNKTVEEVRQHLENGQALAKFEEMVQAQGGDLEDLYRPVNVAHVVEIPAQ
                     ETGVISALPAMDFGLYAMRLGAGRAVKSDALDYETGIVFEKKIGDSVQKGEIVAKVYT
                     NEKIPPQLVTDFQKCVKISDEVKKIREIVEIIS"
     gene            17882..18544
                     /gene="deoC"
                     /locus_tag="VQ862_001152"
     CDS             17882..18544
                     /gene="deoC"
                     /locus_tag="VQ862_001152"
                     /EC_number="4.1.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000773666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribose-phosphate aldolase"
                     /protein_id="HET3115508.1"
                     /translation="MKLNKYIDHTLLKQDAKKKQIDSLLSEAREYDFASVCVNPTWVE
                     HAKKGLEGTDVKVCTVVGFPLGATTSAVKAFETKEAIQNGADEIDMVINVGALKSGNL
                     ALVESDIRAVVEASGDKLVKVIIEACLLTDQEKIVVCQLAQKAGADFVKTSTGFSTGG
                     ATIADVTLMRETVGSDMGVKAAGGARSYADALAFVEAGATRIGTSAGVAILKGELADG
                     DY"
     gene            18531..18920
                     /locus_tag="VQ862_001153"
     CDS             18531..18920
                     /locus_tag="VQ862_001153"
                     /EC_number="3.5.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HET3115509.1"
                     /translation="MATTELIELAIETSKHAYVPYSHFPIGAVLVAKDGNVYTGVNIE
                     NASYPLTNCGERTAIFKAISEGQREFSELIVYGQTEKPISPCGACRQVMVEFFEQDLK
                     VTLVAKDKSTVEMTVGELLPYSFTDLN"
     gene            19011..20063
                     /locus_tag="VQ862_001154"
     CDS             19011..20063
                     /locus_tag="VQ862_001154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001036143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family protein"
                     /protein_id="HET3115510.1"
                     /translation="MNKKQWLGLGLVAVAAVGLAACGNRSSRNAASSSDVKTKAAIVT
                     DTGGVDDKSFNQSAWEGLQAWGKEHNLSKDNGFTYFQSTSEADYANNLQQAAGSYNLI
                     FGVGFALHNAVEEAAKEHTDLNYVLIDDVIKDQKNVASVTFADNESGYLAGVAAAKTT
                     KTKQVGFVGGIESEVISRFEAGFKAGVASVDPSIKVQVDYAGSFGDAAKGKTIAAAQY
                     AAGADIVYQVAGGTGAGVFAEAKSLNESRPENEKVWVIGVDRDQEAEGKYTSKDGKES
                     NFVLVSTLKQVGTTVKDISNKAEKGEFPGGQVIVYSLKDKGVDLAVTNLSEEGKKAVE
                     DAKAKILDGSVKVPEK"
     gene            20207..21742
                     /locus_tag="VQ862_001155"
     CDS             20207..21742
                     /locus_tag="VQ862_001155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000929819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3115511.1"
                     /translation="MAHENVIEMRDITKVFGGFVANDKINLHLRKGEIHALLGENGAG
                     KSTLMNMLAGLLEPTSGEIAVNGQVVNLDSPSKAASLGIGMVHQHFMLVEAFTVAENI
                     ILGSELTKNGVLDIAGASKEIKALSERYGLAVDPSAKVADISVGAQQRVEILKTLYRG
                     ADILIFDEPTAVLTPSEIDELMAIMKNLVKEGKSIILITHKLDEIRAVSDRVTVIRRG
                     KSIETVEIAGATNADLAEMMVGRSVSFKTEKQASKPKEVVLSIKDLVVNENRGVPAVK
                     NLSLDVRAGEIVGIAGIDGNGQSELIQAITGLRKVESGSIELKGDSIVGLHPRQITEL
                     SVGHVPEDRHRDGLILEMMISENIALQTYYKEPHSKNGILNYSNITSYAKKLMEEFDV
                     RAASELVPAAALSGGNQQKAIIAREIDRDPDLLIVSQPTRGLDVGAIEYIHKRLIEER
                     DNGKAVLVVSFELDEILNVSDRIAVIHDGKIQGIVSPETTNKQELGVLMAGGNLGKEK
                     SDV"
     gene            21735..22793
                     /locus_tag="VQ862_001156"
     CDS             21735..22793
                     /locus_tag="VQ862_001156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET3115512.1"
                     /translation="MSKKLQQISVPLISVFLGILLGAIVMWIFGYDAIWGYEELFYTA
                     FGSLRGIGEIFRAMGPLVLIGLGFAVASRAGFFNVGLPGQALAGWILSGWFALSHPDM
                     PRPLMILATIVIALIAGGIVGAIPGILRAYLGTSEVIVTIMMNYIVLYVGNAFIHAFP
                     KDFMQSTDSTIRVGANATYQTPWLAELTGNSRMNIGIFFAIIAVAVIWFMLKKTTLGF
                     EIRAVGLNPHASEYAGISAKRTIILSMIISGALAGLGGAVEGLGTFQNVYVQGSSLAI
                     GFNGMAVSLLAANSPIGILFAAFLFGVLQVGAPGMNAAQVPSELVSIVTASIIFFVSV
                     HYLIERFVKPKKQVKGGK"
     gene            22796..23752
                     /locus_tag="VQ862_001157"
     CDS             22796..23752
                     /locus_tag="VQ862_001157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET3115513.1"
                     /translation="MSIITLLPLLVSSMLIYSAPLIFTSIGGVFSERGGVVNVGLEGI
                     MVMGAFSGVVFNLEFAEQFGAATPWLSLLVAGLVGSVFSIIHAAATVHFRADHVVSGT
                     VLNLMAPALAVFLVKVLYNKGQTDNLSQTFGRFDFPVLANIPVIGDIFFKSTSLLGYL
                     AIAFSFLAWFILFKTQFGLRLRSVGEHPQAADTLGINVYKMRYLGIIISGFLGGIGGA
                     IYAQSISVNFSVTTIVGPGFIALAAMIFGKWNPIGAMLSSLFFGLSQSLAVIGSQLPF
                     LQGVPAVYLQIAPYVLTILVLAAFFGKAVAPKADGINYIKSK"
BASE COUNT         6915 a         4300 c         5436 g         7185 t
ORIGIN      
        1 atcataatgg acaaagggca agctgtcaag aaattacagt tattttagta aaaaaagaag
       61 cagaaaaatt tcattttcta ctccttttct ataggattta tttttctttt tcagaacttt
      121 taacttcagc ttttttggca gatttaatct gaatgtttcc cttgctagtc ataactgctt
      181 tgagatcttt ttcgcttgga ttttcaaggt agtagtcagt gattgtgtcc tcaatatagt
      241 cttgaatagt ccgacgaagt gggcgtgctc ccatttttgg atcataacct aggtcaacca
      301 acttttcctt gaccttgtca gttacatcca aacgaatgtt gttgctagag aggcgcttgt
      361 taacatctgc tagcatgagc tcgacaatct gaaggaggtt atccttgctg agagccttaa
      421 attcgataat gccatcaaaa cggttcataa actctgggct aaagaagtta ccgagttcac
      481 cgaggacaga attggtacgt ccttctctag cagcaccaaa tccaacgcta gcttcggtct
      541 ttcctgtacc tgcatttgag gtcatgataa tgatggcatc cttgaagcta acggtgcgtc
      601 cttgcccgtc tgtcaaacga ccatcgtcca agacttgaag aaacatgtgc ataacatctg
      661 ggtgagcttt ttccacttca tcgagaagga tgagagaata tggattgtgg cgaacttttt
      721 cagttaattg accagcctca tcatagccaa cataacctgg aggagcgccg accaacttag
      781 ccacactatg tttttccatg tattcactca tatcaaagcg aatcatacta tcagcagaac
      841 caaaaagttc gatagccagt tgtttggaaa gttctgtctt accgacacca gttggcccaa
      901 cgaagaggaa gcttccgatt gggcggttag gggtaccaag tccgacacga ttacggcgaa
      961 tagccttggc aatcttatcg actgcatcat cttggccaat aacatgagac ttgagatctt
     1021 cggctagatg gatgagttga gattgttctt tctctttcaa atcaccaaca gggatattgg
     1081 ttttctgctc gataatgtgc tcaatagttt tctcgctgat gataggagta tcctggtctg
     1141 tgatcttttt cttttgcatt tccttatact tggcaatctg gtcgcggaag taggccgcct
     1201 tctcaaaatc ttcttctcgt gtagcttgag acttgagatt ttcagcctca atcaagcgct
     1261 gatcaattac tttaggatcc acaaaattca aggtcaagtt catcttagaa ccagcttcat
     1321 ctaggaggtc aatggccttg tcaggcaaga agcgatcttg gatgtagcga ttggaaagag
     1381 ttgcagctgc ttcaatcgca gcatcggtat attgaacgtg gtggtaatct tcgtatttct
     1441 tttgaatccc tttgagaata gtgattgttt catccaccgt tggttcatcg actttaacag
     1501 gctgcatacg acgctcgagg gcagcatcct tttcaatgat acggtattca ttgagggtag
     1561 tagcaccgac tagttgcagt tctccacgag caagggctgg cttgaggata tttcctgcgt
     1621 ccatattacc atcactcgca gaaccagcac caacaatttc atggatttca tcgataaaga
     1681 ggatgatgtc ttcacgtttg cgaatttctt ccatgagttt ttgcatgcgt tcttcaaatt
     1741 gtcctcgaat ccccgttcct tgaactaagc taaccacatc cagacggatg acttgtttac
     1801 cttggagttt atgtggcaca tcgccatcga caattttctg agctagacct tcgacaacgg
     1861 ccgtttttcc gacaccaggt tcaccgataa ggacaggatt attcttcgtt ctacgattga
     1921 gaatctcgat gacacggata atctcatcgt cgcgcccaat aacggggtca atgtctccac
     1981 gacgggcaat ttcagttaca ttaataccaa attcttccag caggcctttt tcttggctag
     2041 gtggcggagt ttgagcagat ccacgatttt gggaaccata accgccgttt ccaccgtaac
     2101 ctccacctga ttgggttggg ggaataggag gagtattgct agaaggtctg aaattgttta
     2161 gatcattgaa gaaatcacca aagggatcga agtcacgatt gttcagatcc gtcatacctt
     2221 tgaagaggct attgttagga tctgttttga taatcttata gcagttttga cagaggtcaa
     2281 tttgtttttg ttttccattg agattggtgt aaagatgaat tgttgagtcg ttaattttac
     2341 agttttgaca aagcatacat ctacctcatt tctttcttta gcctgacttg tttaaaggtc
     2401 aaaaatagtc aaattctata ctctcattat aacaggattg gggtgtaaag caagtaaaaa
     2461 gattgaagct ttgagaagtt gttacaatga aaatttttgt gaatttggac tataaaaaaa
     2521 tcctatttgt gagacaaaaa ggattttact tagacatgca gggacaatcc cagcttgttt
     2581 tagattagta gagaagttcg taaatttcca ttgcgattaa gtcaatgcta tcaaacgtat
     2641 acgtttcgcg atcttctacg tcacgaaggg taaagattgg gccgttttct tcgtcgtggc
     2701 tgtacgcaac ttctgcaaca acaactcctt cgcgttcaaa attacgtttt aaatttccgc
     2761 catcgtttgc cattgcttca aggcggttga tgattctaac caaatgtgat tccattttga
     2821 ttctccttca tttcttatcg ttactatttt accataaagg aggccaactt gactagaaaa
     2881 aactaagatt tctcgctaat tctgctagtt taaagatttt taaataaatt ggataaaaaa
     2941 tttaaatttt aattcaaaac atgttataat catacagtat tctattttag aaagcagtgt
     3001 gactatgaat ttttcttttt tacctaagta tttaccttat tttaactatg gggctgttgt
     3061 gacgattctt atttctatct gtgttatctt tttgggaact attttgggtg ttgtcttggc
     3121 ttttgggcaa cgttcaaagt ttaaaccgct tgtttggttg gccaacttgt acgtttggat
     3181 tttccgtggg acaccgatga tggttcaaat tatgattgcc tttgctctta tgcatatcaa
     3241 tgctccgact attcagattg gaattttagg tgttgatttt tcgcgtctga ttccagggat
     3301 tttgattatc tctatgaata gtggtgctta tgtttcggag actgttcgtg ccggaatcaa
     3361 tgcggttcca aaaggtcagc tagaggcggc ttattcgcta gggattcgtc ctaaaaatgc
     3421 gatgcgttat gtgattttgc cacaagcaat caaaaatatc ttgccagcat tggggaacga
     3481 atttatcacc attatcaagg acagctccct cttatcagct attggggtca tggagttgtg
     3541 gaatggggct acaacagttt ctacaacaac ctatctacct ttaacaccgc ttttatttgc
     3601 agcattttat tacttgatta tgacctctat tctgacagta gccttgaaag cttttgaaaa
     3661 acatatggga caaggagata agaaataatg acagaaacct tgataaaaat tgaaaattta
     3721 cataaatctt ttggaaagaa tgaagtattg aagggaatca acctcgagat taaaagagga
     3781 gaagttgtcg ttatcatcgg tccttcaggg agtgggaaat ctaccttgct tcgctctatg
     3841 aatttgttgg aggaagcaac caaggggaag gttatctttg agggagtcga tattacggac
     3901 aagaagaatg acttgtttgc catgcgtgag aagatgggca tggttttcca acaatttaac
     3961 ctctttccta atatgactgt gattgaaaat attaccttgt cacctatcaa gaccaaaggt
     4021 gaaagcaggg aagttgctga gaagagagcc caagagcttt tggaaaaagt tggtttgcca
     4081 gataaggcag acgcttatcc acagagtctg tcgggtgggc agcaacaacg gattgccatc
     4141 gcgcgtgggt tggctatgga accagatgtt ttgctctttg acgaaccaac ttcagccttg
     4201 gatcctgaaa tggtaggtga ggtattggct gttatgcaag accttgccaa gtcagggatg
     4261 actatggtta tcgtaacaca tgagatggga tttgcccgtg aggtggcaga tcgtgttatc
     4321 tttatggcag acggtgtggt tgttgaagat gggacacctg agcagatttt tgaacaaacc
     4381 caagaacaac ggactaaaga tttcttgagt aaggttttat aatctatttt aaaatttcaa
     4441 gacaagatta gtgaaaagtt caaccagagc tttttcttat agtttgaaac tataggataa
     4501 cctaggaaag aagtgttaga gggcactagc agtttttggt ataatggaag atatttgaaa
     4561 gaaaagagaa gtgatatgac acagattatt gatgggaaag ctttagcggc caaattgcag
     4621 gggcagttgg ctgaaaagac tgcaaaatta aaggaagaaa cagctctagt gcctggtttg
     4681 gtagtgattt tggttgggga taatccagcc agccaagtct acgttcgcaa caaggagagg
     4741 tcagctcttg cggctggttc ccgtagcgaa gtagtgcgag ttccagagac cattactcaa
     4801 gaggaattgt tagacctgat tgctaaatat aatcaggatc cagcttggca tgggattttg
     4861 gtccagttgc cattaccaaa acatatcgat gaagaggcgg ttttattagc cattgaccca
     4921 gaaaaggatg tggatggttt ccatccccta aacatgggac gtctttggtc tggacatcca
     4981 gtcatgattc cctcgacacc tgcaggaatt atggaaatgt ttcatgaata tgggattgac
     5041 ttggaaggta aaaatgcggt cgtaatcggt cgttcaaata tcgttggaaa acctatggct
     5101 cagcttcttt tggctaaaaa tgcgacagta accttggccc actcacgaac tcataatctt
     5161 gccaaggtgg ctgctaaagc agatattctt gtagtcgcaa tcggccgcgc caagtttgtg
     5221 actgctgact ttgtcaaacc aggtgcggtt gtcattgacg ttgggatgaa ccgagatgaa
     5281 aatgggaagc tctgtggaga tgttgattat gaggcagttg caccacttgc tagccatatc
     5341 acgccagtcc ctggaggtgt cggtcctatg accattacca tgctgatgga gcaaacttat
     5401 caagcagcac ttcggacatt ggatagaaaa taagagaaac attcgattaa tagagtgtat
     5461 tttctatagc tatatctaaa atggcagaaa tgaatattaa attttagata taagattaca
     5521 aaaggaggtc tgcgtctcct ttttgttgta taataaaagt gagagggaaa aaggatgaaa
     5581 gtgattaatc aaaccttact agaaaaagtt attattgaac gttctcgttc aagtcataaa
     5641 ggagattatg gtcgtctgct gctgcttggt ggtacttatc cttatggagg tgccatcatc
     5701 atggctgctt tagcagctgt aaaaagcggt gcaggattgg tgaccgttgg aacggacagg
     5761 gaaaatatcc cggctctgca cagccattta cctgagccta tggccttttc tcttcaagac
     5821 cagcaattgt taaaagagca attggagaag gcagaagtta tcttgctggg gcctggttta
     5881 cgagacgatg cttctggaga aaatctagta aaacaggtct ttgttaattt aagccaaaat
     5941 cagattttga ttgtagacgg aggtgccttg accattcttg ctaggacaag tttgtcattt
     6001 ccctcaagcc agcttatcct aactcctcac caaaaagaat gggaaaaatt atctggaatt
     6061 acgattgaaa agcaaaagga agatgcaacg gctagtgttc tgacttcctt ccctcaagga
     6121 acaattttgg tggagaaagg cccagctact cgtatttggg aagttggcca atctgattat
     6181 taccagttac aggttggtgg tccttatcag gcgactgggg gaatgggaga tactctggct
     6241 gggatgatcg caggatttgt aggccaattc cgacaggcca gtctctacga gcgtgtggca
     6301 gtagcgaccc atcttcattc agccatagcc caagaactat ctcaagaaaa ttatgtggtc
     6361 ttaccgacgg aaatcagcag gtatcttccc aaaataatga aaattatttg tcaacaagat
     6421 agggtaagca aagataaact tgtttaaaat agacagataa atctacttcc ttctcttaat
     6481 ttatgattct tgaaatgcgc ctgctttaag gctaaactag acgtatcaaa gttaagagtt
     6541 tgtttttgta actggaatga gatgaacaaa tcaaatacat aaaagataaa ctcattttta
     6601 ttcgtttggt aaaaataaaa tgcatatttt taaagaaaga ttgatgaaaa atgtagattt
     6661 gatgttttta cttgaataaa aagcggtttc atagtaaaat aagaactgag aatgatggag
     6721 gtaaatcggt ggaaaatctg aagaaaatgg caggtatcaa ggctgctgag ttcgtgagcg
     6781 atggaatggt cgttggactt ggaacaggct cgactgccta ttattttgtc gaagaaatcg
     6841 gtcgtcgtat caaggaagaa ggattgcaga ttacagctgt aacaacttct agtgtgacca
     6901 ctaaacaggc agaaggcctt aatatcccgc tcaagtctat tgaccaagta gactttgtcg
     6961 atgtgacggt tgatggcgcg gatgaagtgg atagtcagtt taatggaatc aaaggcggtg
     7021 gtggtgccct tctcatggaa aaggtggtcg caacaccatc aaaagaatac atttgggtgg
     7081 tggatgaaag caagctggtc gaaaaactag gtgcttttaa attgccagta gaagtggttc
     7141 agtatggtgc agagcaggtc tttcgtcatt ttgaacgagc tggctacaaa ccaagtttcc
     7201 gtgaaaaaga cggccaacgt tttgtgacgg atatgcagaa ttttatcatt gacctcgcct
     7261 tggatgtcat tgaaaatcca attgcttttg gacaagaatt ggaccatgtc gttggtgttg
     7321 tggagcatgg tttattcaac caaatggtgg ataaggtaat cgttgctgga cgagatggag
     7381 ttcagatttc aacttcaaaa aaaggaaaat agaagggggc ataagatgtc taaatttaat
     7441 cgtattcatt tggtggtact ggattctgta ggaatcggtg cagcaccaga tgctaataac
     7501 tttgtcaatg caggggttcc agatggagct tctgacacac tgggacacat ttcaaaaaca
     7561 gttggtttga atgtcccaaa catggctaaa ataggtcttg gaaatattcc tcgtgaaact
     7621 cctcttaaga ctgtagcagc tgaaagcaat ccaactggat atgcaacaaa attagaggaa
     7681 gtatctcttg gtaaggatac tatgactgga cactgggaaa ttatgggact caacattact
     7741 gagcctttcg atactttctg gaacggattc ccagaagaaa tcctgacaaa aatcgaagaa
     7801 ttctcaggac gcaaggttat tcgtgaagcc aacaaacctt attcaggaac ggctgttatc
     7861 gatgattttg gaccacgtca gatggaaact ggagagttga ttatctatac ttcagctgac
     7921 cctgttttgc agattgctgc ccacgaagac attattcctt tggatgaatt gtaccgtatc
     7981 tgtgaatacg ctcgttcgat tacccttgag cgtcctgccc ttcttggtcg catcattgct
     8041 cgcccttatg taggtgaacc aggtaacttc actcgtacgg caaaccgtcg tgacttggct
     8101 gtatctccat tttccccaac tgttttggat aaattgaatg aggctggtat cgatacttat
     8161 gctgtgggta aaatcaacga tatctttaac ggtgctggta tcaaccatga catgggtcac
     8221 aacaagtcaa atagtcatgg aattgataca ctattgaaga ctatgggact tgctgagttt
     8281 gaaaaaggat tctcattcac aaacctagtt gactttgatg ccctttacgg ccatcgtcgt
     8341 aatgctcacg gttaccgtga ttgcttgcat gagtttgatg aacgcttacc tgaaattatc
     8401 gcagctatga gagagaatga ccttctcttg attactgcgg accatggaaa tgacccaacg
     8461 tatgcaggaa cggatcacac tcgggaatat attccattgt tggcctatag ccctgccttt
     8521 aaaggaaatg gtctcattcc agtaggacat tttgcagata tttcagcgac tgttgccgat
     8581 aactttggtg tggaaactgc tatgattggg gaaagtttct tagataaatt ggtataagat
     8641 gacgcgctat gctttgctgg tgagaggtat caatgttggt ggtaagaata aggtcgtcat
     8701 ggcggaactt cgtcaagaat tgacaaactt gggactggaa aaggttgaga gctacatcaa
     8761 cagtggcaat attttcttta cttcgataga ttccaaagcc caattggttg aaaagctaga
     8821 gactttcttt gcagtccatt atccatttat tcagagcttt tctttactga gtctagagga
     8881 ctttgaggcg gaacttgaaa atctaccagc ttggtggagc agagacttgg cacgaaaaga
     8941 ttttctcttt tacactgagg gtttggatgt ggaccaagtc atcgcgacag ttgaaagttt
     9001 agagctgaaa gatgaagtgc tttattttgg aaaacttggg attttctagg ggaaattttc
     9061 tgaagaatcc tattctaaga ctgcctatca taagtacttg ctgaaggtgc ctttctaccg
     9121 ccacattact attcgtaatg ctaaaacctt tgacaaaatt ggtcaaatgc taaaaaaata
     9181 ataaaggaga cacacaatga catttttaaa caaaatccat gaaactgcta ctttcctgaa
     9241 agaaaaggga attgcagccc ctgagttcgg tctaatcctt ggatcaggac ttggagaatt
     9301 ggcagaagaa atcgaaaatc cagttgtagt agactatgct gagattccaa actggggccg
     9361 ttcaacagta gtcggtcatg ctggtaaatt ggtatatggt gaactggcag gtcgcaaggt
     9421 cttggctctt caaggtcgtt tccatttcta tgaagggaat cctctggaag tggtgacttt
     9481 cccagttcgt gtgatgaaag ttcttggatg tgaaggtgtt attgtaacca atgcagctgg
     9541 cggtatcgga tttggtcctg gtaccttgat ggctatctca gaccatatca acatgacggg
     9601 gcaaaatcca ttgatgggtg aaaacttgga tgactttggc ccacgtttcc cagatatgtc
     9661 tagggcctac acaccagaat accgtgccac tgcccatgaa gtggctaaaa aacttaatat
     9721 caagcttgat gaaggtgtct atatcggagt tactggtccg acttatgaaa caccagcaga
     9781 aattcgttcc tataagacac tgggagcaga tgcagttggt atgtctacgg ttcctgaagt
     9841 tatcgtggca gcccactctg gcttgaaagt tctgggaatt tcaagtatca ctaactttgc
     9901 ggctggtttc caagaagaac tcaatcacga agaagttgta gaagtgactg aacgtgttaa
     9961 aggtgatttc aaaggcttgc ttaaagcgat tcttgctgaa ttgtaagaaa aaagatttaa
    10021 aagggggagt gcctctgtct tttcaggatt gactgcctat ccgtattaaa gaagaaacag
    10081 aggaatacta tgagcttctt cctgctctta taactgaaag aagcggaaga ataggtatgt
    10141 ctgatctgat agccagcatt gtgaaagaca agattctagg atactagcat tagcttccta
    10201 gccaagcaga ctagtatgat aaggagagat gagaatgaat tgactttctg aatttctcag
    10261 tcttatcata tatagcacaa tgagatttcg cttgagtctg cttgtaaata aacgaaaaga
    10321 aagataagaa ataatgaaaa ttggtcaacg aattatgcgc tttggcataa aaaattaagt
    10381 atcggagttg tatctgttgt agtcggcttt gatttctagc tccagctgga atttcagcca
    10441 atgaagtaaa gcaagatgta acatctgaag tggtaatagg tgtgctagat tctaaggagg
    10501 aattgaaaga gtcagaaaat gatgctccaa aactagaaac tcctcttaga gaggagccaa
    10561 gactagctcc tcaaacgctt ccggaagcaa gtgaagttct tgaaaacaaa agggaagagt
    10621 caaaagtaga gataacagag ccagctcaag cggatgatat ccgcaaggtt gttggggaat
    10681 tagccaagga tataagtatt actaagttgt atatgacagg tcattctctt ggatgctacc
    10741 tagctcagat tgcagaggtt gaagcttacc aaaaatatcc tgatttttat aaccatgtat
    10801 tgaggaaagt gacaactttc agtgctccta aagtgattac ttccagaact gtttggaatg
    10861 ctaagaatgg tttctgggat gttggtttgg aaagtcgtaa attagctgtt agtggaaaaa
    10921 ttaagcatta tgtggttgat aatgacaatg ttgtgactcc cttgattcat aatgatcgtg
    10981 atattgttac atttacaggt aattcacgct ttaaacaccg ttctcgtggc tattttgaaa
    11041 gtccaatgaa tgatattcct aactttaata ttggtaaaca agctaccttg gataaacatg
    11101 gttatcgtga tccgaaattg gataaagtgc gattctttaa gaaacaggct ctgcctcgat
    11161 cttctagtca accaagcgct gaaccaatgg aaaatattgc cttaggaaaa taggttactc
    11221 aaagttcgac agctttcgga ggagatgcta gaagagctgt ggatggcaaa gtcgatggta
    11281 actatggtca caattctgtc actcatacaa actttcaatc taagccttgg tggcaagtag
    11341 atttggctaa agaagaaacc attcgccaaa tcaatattta caaccgaaca gacactgccc
    11401 aggatagatt ggcaaacttt gatgtcattc ttttagacag ttctggtaaa gaaattgagt
    11461 gaaaacgtat aacatctcct aaagatgtgt cagcacaaat tacgattaac cataaaaaag
    11521 cgcgctatgt tcggattgag ctagaaggct ataatgccct cagtcttgca gaagttgaag
    11581 ttttccgctt tatagctacg aatggtgaaa cggcgataca agtttctaag tcagttcaac
    11641 caatcagtca gactcctgtg aaggataaaa cattgacaat tcaacacagt ggagcttaca
    11701 ttgcccgcta ctccataact tgggaagaag ttacagtaga taaagatgga aaccaagttg
    11761 ttcgtagtca ttcttgggaa ggaaacggtc gcaaccagac tgcaggtttt gtcctcaacc
    11821 tcccaatcaa agaaaatatg agaaatctgc gagttaagat tgagaaaaag acgggcctac
    11881 tatggaatag atggcaaaca atctatgaaa acagaccaat tttagctcaa ccccaccgta
    11941 aaattaccca ttggggtacg acattgaatt ccaaggtgag tgacgatgat gtcttgtaat
    12001 ctgatggtac aatgatagtt agtttgtcta gtttataaga aagtactacc tgagcttgaa
    12061 taggactcag gtagctctct gtgaaagaac aaaattaata ctcaatgaaa atcaaagagc
    12121 aaactaggaa actagccgca ggttgctcaa agcactgctt tgaggttgta gataagactg
    12181 acgaagtcag tcacatatat aatccaaggc gacgttgacg tggtttgaag agattttcga
    12241 agagtataaa cagaaaggta gagcgcgtgt tctaatttga acacgagtag aaaacttttc
    12301 taaaaataaa aacgaaagga tgggtaaact gtattcgctg aactgaatac gggcgactct
    12361 cctctaaatc aaaattaaga aagaaaggaa ttgaccccac cctaaaagca gtgggaaaaa
    12421 gatagttggt ctagcgagca tcgctcactg cgcccaactc ctattttccc ttcgcttttt
    12481 gatgggtttg gtatctttct caatataaaa tataaaataa agaaaggtag agcgtgtgtt
    12541 ttgatttgaa cacgagcgga aaactcggaa aatagataat ctgactgaaa aatcaggatt
    12601 tctcgtcagg ttcctaattt tcagtcgttt tcttctcgct ctttgtatca taaattatgt
    12661 ctatccatat tgctgctcag cagggtgaaa ttgctgataa aattcttctt cctggggatc
    12721 ctcttcgtgc taagtttatt gcggagaatt tccttggtga tgctgtttgt tttaacgaag
    12781 tgcgtaacat gtttggttac actggtactt acaagggtca ccgtgtatct gtcatgggaa
    12841 ctgggatggg aatgccatct atttcgattt atgcgcgtga gttaatcgta gactacggtg
    12901 tgaagaaatt gattcgtgtg ggaactgcag gttctttgaa tgaagaggtt catgttcgtg
    12961 aattagtttt ggcgcaggcg gctgcaacca actcaaacat cgttcgtaat gactggccac
    13021 agtacgattt tccacaaatt gctagctttg atttgcttga taaagcctac catatcgcca
    13081 aagaacttgg tatgactact cacgttggga acgttttgtc atctgatgtc ttttactcaa
    13141 attactttga aaagaatatc gagcttggta aatggggagt caaggctgtg gaaatggaag
    13201 cagcagctct ttactatctt gctgcccaat accatgttga tgcgctagct atcatgacca
    13261 tctctgatag cttggtcaat ccagacgaag acacaactgc agaagaacgt caaaatacct
    13321 tcactgatat gatgaaggtt ggtttggaaa ccttgattgc agaataatta tagccaaaaa
    13381 ggaagccctt tatgaattgt aggacttcct tttcttatcc agaaattgat ctagctctct
    13441 ctgatttcga agaatagtga ctttatgtga atattcttgg caaagttttt ggtaattttc
    13501 tttttgagtt ttgctacgcc catcccaaag aatccatctg ataaactccc agtcaaagcg
    13561 ttcagggcaa tctgccgcca tactttctct gacttttcca cggtatttaa gataacgctt
    13621 aaaggctcta aagagacagg tcaatggcaa aaaattgaga aagatgattt ggtcagcttc
    13681 ttgcattcgt tcttggtagt agcaccaaga ataattacca tcgatgaccc aagctttatg
    13741 cttggtgaga aagtttttta tctcggttaa catccattcg cagtcactgt cttgccaacc
    13801 aggttgaaat tggagtgtgt ccatgtgcag ttttggaatg gagtagtagt tagataactt
    13861 ttctgctaga gttgacttac cagaaccaga atatccgata attgtgattt tcattttcta
    13921 ccttttccta tttggagaca aaaaaacagc ctctatggac tgtttcttat ttagcaagtt
    13981 tagctgaaag acgagcttta tcgcggcttg ctttgttttt gtgaatcaaa cctttagttt
    14041 ctgctttatc gatagctgag ctagcagcac ggaaaagttc ttcagatggg tttgcttcga
    14101 aagcttttat agcagtacgc atagctgatt tttgagctga gttcttttcg ttttgtttaa
    14161 cgttcaattc agcgcgtttg atagctgatt taatgtttgc caatgttctt acctccatat
    14221 ttactaacta taccattata tatgaaaact tacgttttga caagggaaaa ttattttttt
    14281 aagtaaattt catcgatttc atggttcttg cttttatgaa gaatcacttc tgcacgattt
    14341 ctggttggtt caatataatt ttgtagattt gtgagattga tactggtcca gacctgatgg
    14401 gcaaaggctt ccacttcccc aatcggcatc tgagtaaaac gataatagta gctatcaggg
    14461 tcgttttggg ctaggctcag cattttcaag aaacggtcca gataccaact ttcaatatca
    14521 tccactccag catctacata gatggaaaag tcaaagaagt cagtgatata gagacgatcg
    14581 ttttgtggat tttgaaagac attgattccc tcaacaatta caaaatcagc agctttgaca
    14641 ctttgtttct cttcgggtac gatgtcgtaa acttcatgag aatagacagg aatatctaca
    14701 tcttgtccat ttttgatgcg gtccaagaag ttgagaagag cttccatatc atagctttca
    14761 ggaaatcctt tacgatttaa aatcccctgc tcaatcaagg tttgattggg atagagaaaa
    14821 ccatcagttg taaccaactc aaccgtagca tctgtaaacg tacgggacag taggatttga
    14881 agtaggcgac tggttgtgga ttttccaacg gcaacactcc cagaaacccc aataataaaa
    14941 ggttgagatt tactttcacg ttggaggaaa attccttttg aaaaggctaa atcttcctta
    15001 gttcgcttgt aaatctgaat cagatgagcc aaggggagat agatatctgt aacgtcttgg
    15061 agactgattt ggtcattaaa actcttgata gattccaatt cttcttctgt caaaggaggt
    15121 gttgtctttc gatgtaaaga ttgccaagtc tggcggctga ttttttcaaa atgtaaaaat
    15181 tcgttggtca tttgttttcc cctagatatt ttgtctatca taccataaaa atctaaaaaa
    15241 ataaagcggt ttcttgaatg tggtaagtca atggtatata gtataagtga tcaatttatt
    15301 gatgaaatag gagatagatt ctactgattt ataagtttat aagcttataa agggggcttt
    15361 ttagttcaca acttatagga ggtgtactat gaaaatctta aaacgttaca tattggaact
    15421 ctgttttatt ttaagttttg ctttaccttt tataaaagga gccaatgcag ataatggtat
    15481 atgctttgtg gaaacctatt acggttttac ttttttgatg gaacatgcta ttgtaacagc
    15541 tgtctttatc tattcgtttt taattgcttt cttactaaaa aaacgatggg cgaaatggat
    15601 tgctgctggt agttattgct ttttagtcct atggattgcg acagagggtt atttcttccg
    15661 catgtcacta gaagatttga tacgactttg gacaagtttg gaaatcctga cacaaacgta
    15721 tcagttgggc ttttatctaa acattttgtt aggaattttg ttgataataa agtattttaa
    15781 ggttaagcaa tagaaataat aatctgcctg attatagatg ataaactttt tgtttttatc
    15841 tggactgtga tatttatagt tctaaatggt ttattattta taagtgttga aagagattga
    15901 agaaaatggc ttcgtgactt gctttcttcg gtctttttcg ttttattatc aatttgtaaa
    15961 cgatttacaa tttgagtcaa attatggtaa aatagtgtca tgagtaaaat gtattatgca
    16021 gaaaatcctg acgctgctca cgacattcat gagttgagag tagagttgtt gggacaaaaa
    16081 atgacctttt taacggatgc gggtgttttt agcaagaaaa tagttgactt tggaagtcaa
    16141 ctattgctca agtgtcttga ggtcaaccaa ggagaaactg tccttgatgt aggctgtggt
    16201 tacggacctt tgggtttgtc cttagctaag gcttatggag ttcaggctac tatggttgat
    16261 atcaacactc gtgccttgga tttagctcgg agaaatgctg aaaaaaataa tgcaaaagcg
    16321 acgattttcc agtccaacat ctatgaacaa gttgaaggac attttgatca tgtcatttcc
    16381 aatcctccta tccgtgcggg caagcaagtc gttcatgaaa tcattgagaa aagtaaagat
    16441 ttcttggaaa ctggtgggga tttgacaatc gtcatccaga aaaaacaagg ggctccaagt
    16501 gctaagtcca agatggagga tgtgtttggt aattgtgaaa tccttaaaaa agacaaggga
    16561 tactatatcc ttagaagtgt gaaagaatga gagcagttga tttaatacaa aaaaaacgag
    16621 acggtcaaga actgacttca agtgaaattg aatggctggt agaaggctat gtgtcaggaa
    16681 ctgttcctga ttatcagatg tctgcctttg ctatggctgt ttattttaaa ggaatgacga
    16741 ctcgtgaaat ttctgattta acgatgaata tggttaagac tgggcaagag tttgacctgt
    16801 cagccattga tggtgtgaaa gttgacaagc attctactgg tggtgtcggc gataaggtaa
    16861 ccttgattct agctcctctt gttgctagct tcggtgtgcc tgtagcaaaa atgagtggtc
    16921 gtggtcttgg ccatacaggc ggaacaattg ataaattgga gtccattaag ggctatcaag
    16981 tagaacgtag tcaagaggat tttattcgtc aggttcagga tattggagta tctgtcattg
    17041 ggcaatcaga ccagctggtc aaagcagata agcttctcta tgcccttcgt gatgtgaccg
    17101 caactgtcga cacgattcct ttgattgcga gttcggtgat gagcaagaaa attgcggcag
    17161 gggcggatgc tattttgcta gacgtgactg tcggtgaggg tgccttcatg aagacggttg
    17221 atgaggcgcg tgagttggct caaactatgg tagatcttgg taaggttgtt ggacggaaga
    17281 cagtagcagt gattacggat atgagccagc ctttgggacg agcgattgga aatcgtctgg
    17341 aaatccttga agcattggag attttgcaag gtcaaggacg tcaggatatt acccacttta
    17401 tttgtgaatt ggctcaaatt atgcttggtt tggcaaatgt taacaagact gttgaagaag
    17461 ttcgccaaca tcttgagaat ggtcaagcac tggctaagtt tgaggaaatg gtgcaagccc
    17521 aaggtggaga cttggaagac ctctatcgtc ctgtaaatgt agctcatgtg gtggaaatcc
    17581 ctgctcagga aacgggtgtc atttcagctc ttccagctat ggactttggt ctttatgcca
    17641 tgaggctggg tgctggtcgt gcagttaagt ctgatgcctt ggactatgaa acaggaattg
    17701 tttttgaaaa gaagattgga gactccgttc aaaagggtga aattgttgca aaagtataca
    17761 caaatgaaaa aattccacct caactagtta cagatttcca aaaatgtgtt aaaataagtg
    17821 atgaagtgaa aaaaatccgt gaaattgtag aaatcatctc ctaaatggag ggaaaaccga
    17881 aatgaaatta aataaatata tagatcatac gcttttaaaa caagatgcaa agaaaaaaca
    17941 aattgatagt ttgttgtctg aggctagaga gtatgacttt gccagtgttt gcgttaatcc
    18001 gacctgggtt gaacatgcta aaaaaggact tgaaggcaca gatgttaagg tttgcacagt
    18061 agtaggtttc cctttgggag caacaacttc agccgtgaaa gcatttgaga caaaagaagc
    18121 tatccaaaat ggtgcagatg agattgatat ggtgatcaat gttggagctc tcaaatcagg
    18181 taatttagcc ttggttgagt cagatattcg cgcagtagtg gaagcaagtg gtgataagtt
    18241 agtgaaagtc attattgaag cttgccttct gacagaccaa gaaaaaattg ttgtttgcca
    18301 attggcccaa aaagctgggg ctgactttgt taaaacatct actggttttt caactggtgg
    18361 tgctacgata gcagatgtta cattaatgcg tgaaacagtt ggatctgata tgggagtcaa
    18421 ggctgctggt ggagctcgtt cttatgcaga tgctcttgcc tttgtcgaag caggtgcgac
    18481 ccgtatcgga acgtcagctg gggtagctat tttaaaagga gaattggcag atggcgacta
    18541 ctgagttgat tgaactggca attgaaacca gcaaacatgc ctatgtcccc tattctcact
    18601 ttcctatcgg agcagtttta gtagccaaag acggaaatgt ttacacggga gtgaatatcg
    18661 aaaatgctag ctatcctttg accaattgcg gtgagagaac agctattttt aaggctatat
    18721 ctgaaggcca aagagaattt tcagaattga ttgtctatgg tcaaactgaa aaaccgattt
    18781 caccatgtgg tgcttgtcgc caagtaatgg tcgaattttt tgaacaagat ttaaaagtga
    18841 ccttagtcgc aaaagataaa tcgacggtcg agatgacggt cggggagtta cttccatatt
    18901 cttttacaga cttaaattag tctgagtcgc tctttgagtg gcaagggtct ttgtgaccaa
    18961 tcaatccata cttgcaacat cgttgcacat cttatttagg aggttcagta atgaacaaga
    19021 aacaatggct aggtcttggc ctagttgcag tggcagcagt tggacttgct gcatgtggta
    19081 accgctcttc tcgtaacgca gcttcatctt ctgatgtgaa gacaaaagca gcaatcgtca
    19141 ctgatactgg tggtgttgat gacaaatcat tcaaccaatc agcttgggaa ggtttgcagg
    19201 cttggggtaa agaacacaat ctttcaaaag ataacggttt cacttacttc caatcaacaa
    19261 gtgaagctga ctacgctaac aacttgcaac aagcggctgg aagttacaac ctaatctttg
    19321 gtgttggttt tgcccttcac aatgcagttg aagaagcagc taaagaacac actgacttga
    19381 actatgtctt gattgatgat gtgattaaag accaaaagaa tgttgcgagc gtaactttcg
    19441 ctgataatga gtcaggttac cttgcaggtg tggctgcagc aaaaacaact aagacaaaac
    19501 aagttggttt tgtaggtggt atcgaatctg aagttatctc tcgttttgaa gcaggattca
    19561 aggctggtgt tgcgtcagta gacccatcta tcaaagtcca agttgactac gctggttcat
    19621 ttggtgatgc ggctaaaggt aaaacaattg cagccgcaca atacgcagcc ggtgcagata
    19681 ttgtttacca agtagctggt ggtacaggtg caggtgtctt tgcagaggca aaatctctca
    19741 acgaaagccg tcctgaaaat gaaaaagttt gggttatcgg tgttgaccgt gaccaagaag
    19801 cagaaggtaa atacacttct aaagatggca aagaatcaaa ctttgttctt gtatctactt
    19861 tgaaacaagt tggtacaact gtaaaagata tttctaacaa ggcagaaaaa ggagaattcc
    19921 ctggcggtca agtgatcgtt tactcattga aggataaagg ggttgacttg gcagtaacaa
    19981 acctttcaga agaaggtaaa aaagctgtcg aagatgcaaa agctaaaatc cttgatggaa
    20041 gcgtaaaagt tcctgaaaaa taatggatgg aagtcatttc ttaggaagcg gccaagggcc
    20101 gcttttttaa gagttgagac aaagtcattt tgtctcagta aagcttgcta ctagacaaac
    20161 tagcaagttt tattgaaata aaataagact ctgaaaggaa gagcacatgg cacacgaaaa
    20221 tgtcattgag atgcgtgata ttaccaaggt gtttggtgga tttgttgcca acgacaaaat
    20281 caacttgcac ctacgaaaag gtgaaattca tgcactttta ggagaaaatg gggctggtaa
    20341 gtccacgcta atgaacatgt tagcagggct tcttgaacca actagtggtg aaatcgcggt
    20401 caacggtcaa gttgtcaatc tcgactcccc atctaaagca gctagcttgg gaatcgggat
    20461 ggttcaccag cactttatgt tggttgaagc cttcacagtg gctgaaaaca tcattttagg
    20521 tagtgaattg actaaaaatg gtgtgctaga tatcgctgga gctagcaaag aaatcaaggc
    20581 tctttctgaa cgttatggct tagctgttga cccttctgcc aaggtagcag atatctcagt
    20641 tggagcccaa caacgtgtag aaattttaaa aacactttat cggggggctg atatccttat
    20701 ctttgacgaa ccaacggctg ttttgactcc atcagaaatt gatgagttga tggctattat
    20761 gaaaaatctt gtcaaagaag gaaaatcaat tatcttgatt acccacaaat tggatgaaat
    20821 tcgcgcagtt tctgaccgtg ttacagttat ccgtcgtggg aaatcaattg aaaccgttga
    20881 aattgcaggg gctaccaatg ctgatttggc ggaaatgatg gtagggcgtt ctgtttcctt
    20941 taaaacagag aagcaagcct ctaaaccaaa agaagtggtt ttgtctatca aagatttggt
    21001 ggtcaatgaa aaccgtggtg ttccagctgt taaaaatctg tccttggatg ttcgtgctgg
    21061 agagattgtt ggtattgcgg ggattgatgg aaatggtcag tctgaactga ttcaagccat
    21121 tacaggtctt cgtaaggttg aatctggtag cattgagcta aaaggagatt caattgtagg
    21181 cttgcaccca cgtcagatta cagaactaag tgttgggcac gttccagaag accgtcaccg
    21241 tgatggcttg attttggaaa tgatgatatc tgaaaatatt gcccttcaaa cctactataa
    21301 agaaccacat agtaaaaatg gaattttgaa ttattcaaat attacttctt atgctaaaaa
    21361 gctgatggaa gagtttgatg ttcgcgctgc cagtgaatta gttcctgcag ctgcactctc
    21421 aggaggaaat caacaaaaag caattattgc tcgtgaaatt gatcgagatc ctgatctcct
    21481 tatcgttagc cagccaactc gtgggttgga tgtcggtgcc attgagtata tccacaaacg
    21541 cttgattgaa gagcgtgata atggcaaggc tgtccttgtt gtcagctttg aattggatga
    21601 gattttaaac gtctcagacc gtattgccgt tatccacgat ggtaagattc aaggtattgt
    21661 atcaccagaa acaaccaata aacaagaact tggtgtcttg atggctggtg gaaacttggg
    21721 aaaggagaag agtgatgtct aaaaaattac aacaaatttc ggttcccttg atttctgtat
    21781 ttctaggaat tttactcgga gccattgtca tgtggatctt cggttatgat gctatttggg
    21841 gctacgaaga attgttctat acagcctttg gcagtctgcg tgggattgga gaaatcttcc
    21901 gtgctatggg tcctctggtc ttgattggtc ttggttttgc ggttgccagt cgagctggtt
    21961 tctttaacgt cggacttcct ggtcaggctt tggcaggttg gattctcagt ggttggtttg
    22021 cgctgtcgca tccagatatg ccccgtccct tgatgattct agcaaccatc gtgattgcct
    22081 tgattgctgg tgggattgtc ggagcgattc caggtattct tagggcctat ctagggacgt
    22141 cagaggttat tgtaaccatc atgatgaact acattgtctt gtatgtaggg aatgccttta
    22201 tccatgcttt ccctaaagac ttcatgcaaa gtacagattc gaccattcgt gttggggcta
    22261 atgcaactta tcagacacct tggttggctg agttgactgg taactcacgg atgaatattg
    22321 gtattttctt tgccatcatt gccgttgcag ttatttggtt catgctcaag aaaacaactc
    22381 ttggttttga aatccgtgca gttggtctta atccacatgc ttcagaatat gctggtattt
    22441 ctgccaagcg gactattatc ctatctatga ttatttcagg tgccttggca ggtcttggtg
    22501 gagctgttga aggtttggga accttccaga acgtctatgt tcaaggttcg tcattagcta
    22561 tcggatttaa cggaatggcg gttagtttgc ttgcggccaa ctcaccaatt ggtatactct
    22621 ttgcagcctt cctatttggc gttctccaag ttggggctcc tggtatgaat gcggcgcagg
    22681 taccatctga gcttgtcagc attgtaacag cgtctattat cttctttgtc agtgttcatt
    22741 accttatcga acgctttgtc aaaccgaaaa aacaagttaa aggaggtaag taaagatgtc
    22801 tattataacc ttgctccccc tcttggtgtc ttctatgctg atttactcag cacctctcat
    22861 ctttacaagt atcggtggtg ttttctctga acgtggtggt gtggtaaacg ttggccttga
    22921 aggaattatg gttatgggtg ccttttctgg agttgtcttt aaccttgaat ttgcagaaca
    22981 atttggagca gcaactccat ggctatcctt gcttgtagca ggattggttg gtagtgtttt
    23041 ctctatcatc cacgcagcag cgacggttca tttccgtgca gaccatgttg tcagcggtac
    23101 ggtattgaac ttgatggcgc ctgccttggc tgttttctta gttaaagttc tttataacaa
    23161 aggacaaacc gacaacctaa gtcaaacttt tggacgcttt gatttcccag tcttggcaaa
    23221 tatcccagtg attggtgata tcttcttcaa gtcaactagt ctacttggtt atctggcgat
    23281 tgccttctca ttccttgctt ggtttattct ctttaagact caatttggtc ttcgtctccg
    23341 ctctgtcggt gaacatcctc aagcagcgga taccttggga atcaacgtct acaagatgag
    23401 atatttaggg attattattt caggttttct aggtggaatt ggcggagcga tttatgcgca
    23461 atcaatctca gttaacttct cagtgacaac tattgttgga cctggattta tcgcccttgc
    23521 tgcgatgatc tttgggaaat ggaatccaat cggtgctatg ctttctagtc tcttctttgg
    23581 actttcacaa agtttggctg ttatcggttc tcaattgccg ttcctacaag gagtgccagc
    23641 ggtttatctt caaattgcac cttatgtttt gacaattctt gtcttagcag ccttctttgg
    23701 aaaagcagtc gcaccaaaag cagatggtat caactacatc aaatcaaaat aagcatacaa
    23761 aaaaacgtca gtccaatgac tgaactgccc cccaaaagtt agacagaaaa aatctaactt
    23821 ttggggtgtt tttatt
//
LOCUS       DAVBOD010000026        23291 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 640-05
            SAMEA1012484-rid20186543.denovo.026, whole genome shotgun sequence.
ACCESSION   DAVBOD010000026 DAVBOD010000000
VERSION     DAVBOD010000026.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012484
            Sequence Read Archive: ERR059358
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 23291)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23291)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979948.1
            Genome Coverage       :: 595x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:03:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,266
            CDSs (total)                      :: 2,219
            Genes (coding)                    :: 2,091
            CDSs (with protein)               :: 2,091
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 71 of 128
            Pseudo Genes (incomplete)         :: 50 of 128
            Pseudo Genes (internal stop)      :: 33 of 128
            Pseudo Genes (multiple problems)  :: 22 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23291
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012484-rid20186543.denovo.026"
                     /strain="NIG 640-05"
                     /db_xref="taxon:1313"
     gene            60..929
                     /locus_tag="VQ862_001158"
     CDS             60..929
                     /locus_tag="VQ862_001158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid ABC transporter
                     permease"
                     /protein_id="HET3115514.1"
                     /translation="MLQQLVNGLILGSVYALLALGYTMVYGIIKLINFAHGDIYMMGA
                     FIGYFLINSFQMNFFVALIVAMLATAILGVVIEFLAYRPLRHSTRIAVLITAIGVSFL
                     LEYGMVYLVGANTRAFPQAIQTVRYDLGPISLTNVQLMILGISLILMILLQVIVQKTK
                     MGKAMRAVSVDSDAAQLMGINVNRTISFTFALGSALAGAAGVLIALYYNSLEPLMGVT
                     PGLKSFVAAVLGGIGIIPGAALGGFVIGLLETFATAFGMSDFRDAIVYGILLLILIVR
                     PAGILGKNVKEKV"
     gene            933..1889
                     /locus_tag="VQ862_001159"
     CDS             933..1889
                     /locus_tag="VQ862_001159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid ABC transporter
                     permease"
                     /protein_id="HET3115515.1"
                     /translation="MKENLKVNILWLLLLLAGYSLISVLVSVGVLNLFYVQILQQIGI
                     NIILAVGLNLIVGFSGQFSLGHAGFMAIGAYAAAIIGSKSPTYGAFFGAMLVGALLSG
                     AVALLVGIPTLRLKGDYLAVATLGVSEIIRIFIINGGSLTNGAAGILGIPNFTTWQMV
                     YFFVVITTIATLNFLRSPIGRSTLSVREDEIAAESVGVNTTKIKIIAFVFGAITASIA
                     GSLQAGFIGSVVPKDYTFINSINVLIIVVFGGLGSITGAIVSAIVLGILNMLLQDVAS
                     VRMIIYALALVLVMIFRPGGLLGTWELSLSRFFKKSKKEEQN"
     gene            1889..2653
                     /locus_tag="VQ862_001160"
     CDS             1889..2653
                     /locus_tag="VQ862_001160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002913097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3115516.1"
                     /translation="MALLEVKQLTKHFGGLTAVGDVTLELNEGELVGLIGPNGAGKTT
                     LFNLLTGVYEPSEGTVTLDGHLLNGKSPYKIASLGLGRTFQNIRLFKDLTVLDNVLIA
                     FGNHHKQHVFTSFLRLPAFYKSEKELKAKALELLKIFDLDGDAETLAKNLSYGQQRRL
                     EIVRALATEPKILFLDEPAAGMNPQETAELTELIRRIKDEFKITIMLIEHDMNLVMEV
                     TERIYVLEYGRLIAQGTPDEIKTNKRVIEAYLGGEA"
     gene            2653..3363
                     /locus_tag="VQ862_001161"
     CDS             2653..3363
                     /locus_tag="VQ862_001161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000062217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3115517.1"
                     /translation="MSMLKVENLSVHYGMIQAVRDVSFEVNEGEVVSLIGANGAGKTT
                     ILRTLSGLVRPSSGKIEFLGQEIQKMPAQKIVAGGLSQVPEGRHVFPGLTVMENLEMG
                     AFLKKNREENQANLKKVFSRFPRLEERKNQDAATLSGGEQQMLAMGRALMSTPKLLLL
                     DEPSMGLAPIFIQEIFDIIQDIQKQETTVLLIEQNANKALAISDRGYVLETGKIVLSG
                     TGKELASSEEVRKAYLGG"
     gene            3671..4327
                     /locus_tag="VQ862_001162"
     CDS             3671..4327
                     /locus_tag="VQ862_001162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HET3115518.1"
                     /translation="MAVKDFMTRKVVYISPDTTVSHAADLMREQGLHRLPVIENDQLV
                     GLVTEGTIAQASPSKATSLSIYEMNYLLNKTKVKDVMIRDVVTVSGYASLEDATYLML
                     KNKISILPVVDNHQVYGVITDRDVFQAFLEIAGYGEEGIRVRFVTEDEVGVLGKIVSL
                     IVEENLNISHTVNIPRKDGKVIIEVQIDGSIDLPALKEKFEANGIQVEEIARTSAKVL
                     "
     gene            4435..5530
                     /gene="prfB"
                     /locus_tag="VQ862_001163"
     CDS             join(4435..4506,4508..5530)
                     /gene="prfB"
                     /locus_tag="VQ862_001163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511312.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 2"
                     /protein_id="HET3115519.1"
                     /translation="MDISVIRQKIDANREKLASFRGSLDLEGLEEEIAILENKMTEPD
                     FWNDNIAAQKTSQELNELKNTYNTFHKMEELQDEVEILLDFLAEDESVHDELVAQLAE
                     LDKIMTSYEMTLLLSEPYDHNNAILEIHPGSGGTEAQDWGDMLLRMYTRYGNAKGFKV
                     EVLDYQAGDEAGIKSVTLSFEGPNAYGLLKSEMGVHRLVRISPFDSAKRRHTSFTSVE
                     VMPELDDTIEVEIREDDIKMDTFRSGGAGGQNVNKVSTGVRLTHIPTGIVVQSTVDRT
                     QYGNRDRAMKMLQAKLYQMEQDKKAAEVDSLKGEKKEITWGSQIRSYVFTPYTMVKDH
                     RTSFEVAQVDKVMDGDLDGFIDAYLKWRIS"
     gene            5548..6240
                     /gene="ftsE"
                     /locus_tag="VQ862_001164"
     CDS             5548..6240
                     /gene="ftsE"
                     /locus_tag="VQ862_001164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012130521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division ATP-binding protein FtsE"
                     /protein_id="HET3115520.1"
                     /translation="MSIIEMRDVVKKYDNGTTALRGVSVSVQPGEFAYIVGPSGAGKS
                     TFIRSLYREVKIDKGSLSVAGFNLVKIKKKDVPLLRRSVGVVFQDYKLLPKKTVYENI
                     AYAMEVIGENRRNIKRRVMEVLDLVGLKHKVRSFPNELSGGEQQRIAIARAIVNNPKV
                     LIADEPTGNLDPDNSWEIMNLLERINLQGTTILMATHNSQIVNTLRHRVIAIENGRVV
                     RDESKGEYGYDD"
     gene            6233..7159
                     /locus_tag="VQ862_001165"
     CDS             6233..7159
                     /locus_tag="VQ862_001165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET3115521.1"
                     /translation="MISRFFRHLFEALKSLKRNGWMTVAAVSSVMITLTLVAIFASVI
                     FNTAKLATDIENNVRVVVYIRKDVEDNSQTIEKEGQTVTNNDYHKVYDSLKNMSTVKS
                     VTFSSKEEQYEKLTEIMGDNWKIFEGDANPLYDAYIVEANTPNDVKTIAEDAKKIEGV
                     SEVQDGGANTERLFKLASFIRVWGLGIAALLIFIAVFLISNTIRITIISRSREIQIMR
                     LVGAKNSYIRGPFLLEGAFIGLLGAIAPSVLVFIVYQIVYQSVNKSLVGQNLSMISPD
                     LFSPLMIALLFVIGVFIGSLGSGISMRRFLKI"
     gene            7445..9625
                     /locus_tag="VQ862_001166"
     CDS             7445..9625
                     /locus_tag="VQ862_001166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000974069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HET3115522.1"
                     /translation="MMKDTFKNVLSFEFWQKFGKALMVVIAVMPAAGLMISIGKSIVM
                     INPTFTPLVITGGILEQIGWGVIGNLHILFALAIGGSWAKERAGGAFAAGLAFILINR
                     ITGTIFGVSGDMLKNPDAMVTTFFGGSIKVADYFISVLEAPALNMGVFVGIISGFVGA
                     TAYNKYYNFRKLPDALSFFNGKRFVPFVVILRSAIAAILLAAFWPVVQTGINNFGIWI
                     ANSQETAPILAPFLYGTLERLLLPFGLHHMLTIPMNYTALGGTYDILTGAAKGTQVFG
                     QDPLWLAWVTDLVNLKGTDTSQYQHLLDTVHPARFKVGQMIGSFGILMGVIVAIYRNV
                     DADKKHKYKGMMIATALATFLTGVTEPIEYMFMFIATPMYLVYSLVQGAAFAMADVVN
                     LRMHSFGSIEFLTRTPIAISAGIGMDIVNFVWVTVLFAVIMYFIANFMIQKFNYATPG
                     RNGNYETAEGSEETSSEVKVAAGSQAVNIINLLGGRVNIVDVDACMTRLRVTVKDADK
                     VGNAEQWKAEGAMGLVMKGQGVQAIYGPKADILKSDIQDILDSGEIIPETLPSQMTEA
                     QQNTVHFKNLTEEVYSVADGQVVGLEQVKDPVFAQKMMGDGFAVEPANGNIVSPVSGT
                     VSSIFPTKHAFGIVTEAGLEVLVHIGLDTVSLEGKPFTVHVAEGQKVAAGDLLVTADL
                     DAIRAAGRETSTVVVFTNGDAIKSVKLEKTGSLAAKTAVAKVEL"
     gene            9677..10492
                     /locus_tag="VQ862_001167"
     CDS             9677..10492
                     /locus_tag="VQ862_001167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HET3115523.1"
                     /translation="MKFLTLNTHSWMEKEAEEKFQILLEDILEKDYDLICFQEINQEM
                     TSSEVEVNDLYQALPAAEPIHQDHYVRLLVEKLLEQGKNYYWTWAYNHIGYDRYHEGV
                     AILSKTPIEAREILVSDVDDPTDYHTRRVALAETVVDGKELAVASVHLSWWDKGFQEE
                     WARFEAVLKKLNKPLLLAGDFNNPAGQEGYQAILASPLGLQDAFEVAQEKSGSYTVPP
                     EIDGWKGNTEPLRIDYVFTTKELAVENLHVVFDGNKSPQVSDHYGLNAILNWK"
     gene            10632..11975
                     /locus_tag="VQ862_001168"
     CDS             10632..11975
                     /locus_tag="VQ862_001168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HET3115524.1"
                     /translation="MSFTKFQFKNYIREALKELKFTTPTEVQDKLIPIVLAGRDLVGE
                     SKTGSGKTHTFLLPIFQQLDEASDSVQAVITAPSRELATQIYQVARQISAHSDVEVRV
                     VNYVGGTDKARQIEKLASNQPHIVIGTPGRIYDLVKSGDLAIHKAKTFVVDEADMTLD
                     MGFLETVDKIADSLPKDLQFMVFSATIPQKLQPFLKKYLSNPVMEKIKTKTVISDTID
                     NWLISTKGHDKNAQIYQLTQSMQPYLAMIFVNTKTRADELHSYLTAQGLKVAKIHGDI
                     APRERKRIMNQVQNLDFEYIVATDLAARGIDIEGVSHVINDAIPQDLSFFVHRVGRTG
                     RNGLPGTAITLYQPSDDSDIRELEKLGIKFSPKMVKDGEFQDTYDRDRRANREKKQDK
                     LDIEMIGLVKKKKKKVKPGYKKKIQWAVDEKRRKTKRAENRARGRAERKAKRQTF"
     gene            12352..13542
                     /locus_tag="VQ862_001169"
     CDS             12352..13542
                     /locus_tag="VQ862_001169"
                     /EC_number="2.5.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000003937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine adenosyltransferase"
                     /protein_id="HET3115525.1"
                     /translation="MSERKLFTSESVSEGHPDKIADQISDAILDAILAKDPEAHVAAE
                     TAVYTGSVHVFGEISTNAYVDINRVVRDTIAEIGYTNTEYGFSAETVGVHPSLVEQSP
                     DIAQGVNEALEVRGNADQDPLDLIGAGDQGLMFGFAVDETEEFMPLPIALSHKLVRRL
                     AELRKSGEISYLRPDAKSQVTVEYDENDRPVRVDTVVISTQHDPEATNEQIHQDVIDK
                     VIKEVIPSSYLDDKAKFFINPTGRFVIGGPQGDSGLTGRKIIVDTYGGYSRHGGGAFS
                     GKDATKVDRSASYAARYIAKNIVAAGLAKKAEVQLAYAIGVAQPVSVRIDTFGTGTVA
                     ESQLEKAARQIFDLRPAGIIQMLDLKRPIYRQTSAYGHMGRTDIDLPWERLDKVDALK
                     EAVK"
     gene            14095..15030
                     /locus_tag="VQ862_001170"
     CDS             14095..15030
                     /locus_tag="VQ862_001170"
                     /EC_number="1.3.98.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate oxidase"
                     /protein_id="HET3115526.1"
                     /translation="MVSTKTQIAGFEFDNCLMNAAGVACMTIEELEEVKNSAAGTFVT
                     KTATLDFRQGNPEPRYQDVPLGSINSMGLPNNGLDYYLDYLLDLQEKESNRTFFLSLV
                     GMSPEETHTILKKVQESDFRGLTELNLSCPNVPGKPQIAYDFETTDRILAEVFAYFTK
                     PLGIKLPPYFDIVHFDQAAAIFNKYPLKFVNCVNSIGNGLYIEDESVVIRPKNGFGGI
                     GGEYIKPTALANVHAFYQRLNPQIQIIGTGGVLTGRDAFEHILCGASMVQVGTTLHKE
                     GVSAFDRITNELKAIMVEKGYESLEDFRGKLRYID"
     gene            15064..16101
                     /locus_tag="VQ862_001171"
     CDS             15064..16101
                     /locus_tag="VQ862_001171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001845438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HET3115527.1"
                     /translation="MLAIEESQKLTLSNLPSLSLFTGTDQGQFEVMKSQMLKQIGYDS
                     ADLNFAYFDMKEVVYKDVELELVSLPFFADEKIVILDYFMDITTAKKRFLTDDELKSF
                     EEYLDNPSPTTKLIIFAEGKLDSKRRLVKLLKRDAKVFDAVEVKEQELRQYFQKWSQK
                     QGLQFTNHSFENLLIKSGFQFSEIQKNLLFLQSYKANSVIEEEDIVNAIPKTLQDNIF
                     DLTQFILTKKMDQARDLVRDLTLQGEDEIKLIAVMLGQFRTFTQVKILAESGQTESQI
                     ASSLGSYLGRNPNPYQIKFALRDSRGLSLSFLKQAISYLIETDYQIKTGLYEKGFLFE
                     KALLQIASQVN"
     gene            16274..16879
                     /locus_tag="VQ862_001172"
     CDS             16274..16879
                     /locus_tag="VQ862_001172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase"
                     /protein_id="HET3115528.1"
                     /translation="MAIILPELPYAYDALEPYIDAETMHLHHDKHHQTYVNNANAALE
                     KHPEIGEDLEALLADVESIPADIRQALINNGGGHLNHALFWELMTPEKTAPSAELAAA
                     IDATFGSFEEFQAAFTAAATTRFGSGWAWLVVNKEGKLEVTSTANQDTPISEGKKPIL
                     GLDVWEHAYYVKYRNVRPDYIKAFFSVINWNKVDELYAAAK"
     gene            17035..17565
                     /locus_tag="VQ862_001173"
     CDS             17035..17565
                     /locus_tag="VQ862_001173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YutD family protein"
                     /protein_id="HET3115529.1"
                     /translation="MRKEIAPELYNYNKFPGPEFHLHGDKVETEGIAFSLVENIKDAF
                     DVTTFNQRFSEVLTKFDYIVGDWSNEQLRLRGFYKDDRTEEKLEKISRLQDYLLEYCS
                     YGCAYFVLENEAPKRASFDKKMRKTEEETPSRKGKKPTQTKRKSNADKKNRRRQKDQH
                     SQKEDKEQRHFVIRQK"
     gene            17586..18671
                     /gene="rlmN"
                     /locus_tag="VQ862_001174"
     CDS             17586..18671
                     /gene="rlmN"
                     /locus_tag="VQ862_001174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000804770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2503)-C(2))-methyltransferase
                     RlmN"
                     /protein_id="HET3115530.1"
                     /translation="MKPSIHSLTHQTMQEWVLEQGEKKFRADQIWEWLYRKRVQSFEE
                     MTNLSKDLIAKLNDQFVVNPLKQGIVQESADGTVKYLFELPDGMLIETVLMCQHYGLS
                     VCVTTQVGCNIGCTFCASGLIKKQRDLNNGEIVAQIMLVQKYFDERGQDERISHIVVM
                     GIGEPFDNYNNVLNFFRTINDDKGMAIGARHITVSISGLAHKIRDFADEGVQVNLAVS
                     LHAPNNELRSSIMKINRAFPIEKLFAAIEYYIETTNRRVTFEYIMLNEVNDGVEQALE
                     LAELLKNIKKSSYVNLIPYNPVSEHDQYSRSPKERVLAFYDTLKKKGGNCVVRQEHGT
                     DIDAACGQLLFNTMKRDRQKAVAAVNP"
     gene            18671..19153
                     /locus_tag="VQ862_001175"
     CDS             18671..19153
                     /locus_tag="VQ862_001175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000976721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HET3115531.1"
                     /translation="MMKKTYNHILVWGVIFYSICIVYFCFTPQEQSTVGVGTPDIQHL
                     GRLVFLLTPFNSLWKLGEVSDIGQLCWIFLQNILNVFLFFPLIFQLLYLFPNLRKTKK
                     VLLFSFLVSLGIECTQLILDFFFDFNRVFEIDDLWTNTLGGYLAWLLYKRLHKNKIRN
                     "
     gene            19155..20696
                     /locus_tag="VQ862_001176"
     CDS             19155..20696
                     /locus_tag="VQ862_001176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002918612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HET3115532.1"
                     /translation="MSILEVKNLSHGFGDRAIFEDVSFRLLKGEHIGLVGANGEGKST
                     FMSIVTGKMLPDEGKVEWSKYVTAGYLDQHSVLAERQSVRDVLRTAFDELFKAEARIN
                     DLYMEMAEDGADVDALMEEVGELQDRLESRDFYTLDAKIDEVARALGVMDFGMDTDVT
                     SLSGGQRTKVLLAKLLLEKPDILLLDEPTNYLDAEHIDWLKRYLQNYENAFVLISHDI
                     PFLNDVINIVYHVENQQLTRYSGDYYQFQEVYAMKKSQLEAAYERQQKEIADLKDFVA
                     RNKARVATRNMAMSRQKKLDKMDIIELQSEKPKPSFDFKPARTPGRFIFQTKNLQIGY
                     DLPLTKPLNLTFERNQKVAIIGANGIGKTTLLKSLLGIISPIAGEVERGDYLELGYFE
                     QEVEGGNRQTPLEAVWNAFPALNQAEVRAALARCGLTTKHIESQIQVLSGGEQAKVRF
                     CLLMNRENNVLVLDEPTNHLDVDAKDELKRALKEYRGSILMVCHEPDFYEGWIDQIWD
                     FNNLT"
     gene            complement(20752..21555)
                     /locus_tag="VQ862_001177"
     CDS             complement(20752..21555)
                     /locus_tag="VQ862_001177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000731914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HET3115533.1"
                     /translation="MKKLATLLLLSTVALAGCSSVQRSLRGDDYVDSSLAAEESSKVA
                     AQSAKELNDALTNENANFPQLSKEVAEDEAEVILHTSQGDIRIKLFPKLAPLAVENFL
                     THAKEGYYNGITFHRVIDGFMVQTGDPKGDGTGGQSIWHDKDKTKDKGTGFKNEITPY
                     LYNIRGALAMANTGQPNTNGSQFFINQSSTDTSSKLPTSKYPQKIIEAYKEGGNPSLD
                     GKHPVFGQVIDGMDVVDKIAKAEKDEKDKPTTAITIDSIEVVKDYDFKS"
     gene            complement(21638..21859)
                     /locus_tag="VQ862_001178"
     CDS             complement(21638..21859)
                     /locus_tag="VQ862_001178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3115534.1"
                     /translation="MSFYGLFYNGIAITPNTYLSAWFVNFIAALPLNFLIVEPIARFI
                     LSSFQKPFTGEEVEEVEDFQDDDEIPTII"
     gene            complement(22338..22547)
                     /locus_tag="VQ862_001179"
     CDS             complement(22338..22547)
                     /locus_tag="VQ862_001179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000953868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3115535.1"
                     /translation="MLSVNTILEKFYKEHQVKPFISPERELDTWLLSPKPVPKRNMDL
                     LVDDSLAGDIILLWRIQFGTFTTET"
     gene            22717..22989
                     /gene="rpsP"
                     /locus_tag="VQ862_001180"
     CDS             22717..22989
                     /gene="rpsP"
                     /locus_tag="VQ862_001180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002884675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S16"
                     /protein_id="HET3115536.1"
                     /translation="MAVKIRLTRMGSKKKPFYRINVADSRSPRDGRFIETVGTYNPLV
                     AENQVTLKEDRVLAWLANGAQPSDTVRNILSKEGVLKKFHDSKFSK"
     gene            23009..23248
                     /locus_tag="VQ862_001181"
     CDS             23009..23248
                     /locus_tag="VQ862_001181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KH domain-containing protein"
                     /protein_id="HET3115537.1"
                     /translation="MDTIENLIIAIVKPLISQPDALTIKIEDTPEFLEYHLNLDQSDV
                     GRVIGRKGRTISAIRTIVYSVPTEYKKVRIVIDEK"
BASE COUNT         6969 a         4223 c         5092 g         7007 t
ORIGIN      
        1 agaacctatc aaaaagtgag ggaaacccct cggaattata aatagaaaga gtgaatctta
       61 tgctccaaca actcgtaaat ggtttgattc taggtagtgt ttacgcgctg ttagccctag
      121 gatataccat ggtttacgga attatcaagc tcatcaactt cgcccatggt gatatttata
      181 tgatgggagc ctttatcggt tatttcttga tcaattcttt ccaaatgaat ttctttgtag
      241 cgcttattgt agctatgcta gcgacagcta ttcttggtgt cgtgattgag tttcttgctt
      301 accgaccttt gcgccactct actcgtattg ctgttttgat tacggctatt ggggtttctt
      361 tcctattgga gtatggaatg gtctatctgg ttggtgccaa tacccgtgcc ttccctcaag
      421 cgattcaaac agttcgatat gatttgggac caattagctt aacaaatgtg cagttaatga
      481 ttttgggcat ttccttgatt ttgatgattt tgttacaagt cattgtccaa aagactaaga
      541 tggggaaagc catgcgtgca gtatcagtag atagcgacgc ggcgcaattg atggggatca
      601 atgtaaaccg tacgattagc tttaccttcg ctttgggttc tgctcttgcg ggtgcggctg
      661 gtgttctgat tgctctttat tataactctc ttgagccttt gatgggggtt actccaggtc
      721 ttaaatcttt cgttgccgca gtacttggtg gtatcggaat tattcctggt gcggctcttg
      781 gtggctttgt gattggtcta ttggaaacct ttgcgactgc ctttgggatg tcagatttcc
      841 gtgatgccat tgtttatgga atcttgttgt tgatcttgat tgtccgccca gctggtatcc
      901 ttggtaagaa tgtgaaagag aaggtgtaaa cgatgaagga aaatttaaaa gttaatattc
      961 tatggttact ccttttgtta gctggctata gcttgattag tgtactggtt tcagtcggag
     1021 tacttaatct attctatgta cagattttac aacaaattgg aattaatatt attttggctg
     1081 ttggtctcaa cttaatcgtt ggtttttcag gacaattttc acttggtcat gctggtttca
     1141 tggcgattgg tgcctatgca gcagctatta ttggttctaa atcaccaacc tacggtgcct
     1201 tctttggagc tatgcttgta ggggctttgc tttcaggagc agttgcctta cttgtcggca
     1261 ttccaacctt gcgcttgaag ggggactatc ttgcggtagc aactctaggt gtttctgaaa
     1321 ttatccgtat ctttatcatc aatggtggaa gccttacaaa tggtgcggca ggtattttag
     1381 ggattcctaa ctttacaact tggcaaatgg tttacttctt tgtcgtgatt acaaccattg
     1441 caaccttgaa cttcttgcgt agcccaattg gtcgttcaac cctctctgtt cgtgaagatg
     1501 aaatcgctgc tgagtcagtt ggggttaata cgactaaaat taaaatcatc gcttttgtct
     1561 ttggtgccat tactgcaagt attgctgggt cacttcaggc aggatttatc gggtctgttg
     1621 taccgaaaga ttacaccttc atcaactcaa tcaacgtttt gattattgtt gtatttggtg
     1681 gactcggttc cattacaggt gcgattgttt cggctattgt tctgggaatt ttaaatatgc
     1741 ttctccaaga tgttgctagt gtgcgtatga ttatttacgc tttggccttg gtattggtaa
     1801 tgattttcag accaggtgga ctccttggaa cgtgggaact gagcctatca cgtttcttta
     1861 aaaaatctaa gaaggaggaa caaaactaat ggcattactt gaagtaaaac agttaaccaa
     1921 acattttggt ggtctaacag ctgttggaga tgtgactctt gaattgaacg aaggggaact
     1981 ggttggatta atcggtccaa acggagctgg gaaaaccacc cttttcaacc ttttgaccgg
     2041 tgtttatgaa ccaagcgagg gaacagtaac cctagatggt caccttttga atgggaaatc
     2101 accttataag attgcctctt tgggacttgg acgtactttc caaaatatcc gtctctttaa
     2161 agatttaaca gttttagata atgttttgat tgcttttgga aaccatcaca aacagcatgt
     2221 ttttactagt ttcttacgct taccagcttt ttacaagagt gaaaaagaat taaaggctaa
     2281 agctttggaa ttgttgaaaa tctttgattt agatggtgat gcagagactc ttgctaaaaa
     2341 tctttcctac ggacaacaac gtcgtttgga aattgttcgt gcccttgcta cggaacctaa
     2401 aattctcttc ttagatgaac cagcagcagg tatgaaccca caggaaacag ccgaattgac
     2461 tgagttaatt cgtcgtatca aagatgaatt taagattaca atcatgttga ttgaacacga
     2521 tatgaatctg gtcatggaag taacagaacg tatctacgta cttgaatatg gccgtttaat
     2581 tgctcaagga actccagacg aaattaagac caataaacgc gttatcgaag cttatctagg
     2641 aggtgaagcc taatgtctat gttaaaagtt gaaaatcttt ctgtgcatta cggtatgatc
     2701 caagcagtcc gtgatgtaag ctttgaagtt aatgaaggag aagttgtttc ccttatcggt
     2761 gccaacggtg caggtaagac aactattctt cgcaccttgt caggtttggt tcgaccaagt
     2821 tcaggaaaga ttgaattttt aggtcaagaa atccaaaaaa tgccagctca gaaaatcgtg
     2881 gcaggtggtc tttcacaagt tccagaagga cgccacgtct ttcctggctt gactgttatg
     2941 gaaaatcttg aaatgggagc tttcttaaag aaaaatcgtg aagaaaatca agcaaacttg
     3001 aagaaggttt tctcacgctt tcctcgtctt gaagaacgta agaaccaaga tgcagctact
     3061 ctttcaggag gggaacaaca aatgcttgcc atgggacgcg ctcttatgtc aacaccaaaa
     3121 cttcttcttt tagatgaacc atcaatggga cttgccccaa tcttcatcca agagattttt
     3181 gatatcattc aagatattca gaagcaagaa acaaccgtcc tcttgattga acaaaatgcc
     3241 aataaagcac tcgcaatctc tgaccgagga tatgtattgg aaacaggaaa aatcgtccta
     3301 tcagggacag gaaaagaact cgcttcatca gaagaagtca gaaaagcata tctaggtggc
     3361 taaaacaatc cagtggattg ttttagtcgg cagatgaaga ttacgaagta atcatcaata
     3421 tagtccgggg gaccttttta gtcggtagat tgagattgca aacaaatatg catctacatt
     3481 gaaagcttaa tttctaataa ttgaaaaaat cgaatgaaaa atttcttacc ttcattcaca
     3541 gagctctatt tcagagctct ttttgctagc ttattcatac ttttctgaat ttcgaaaaag
     3601 aaatgtaagc gtttgataga tttacaaaaa gattgtataa tagggataag aatagaaaag
     3661 gagaagtctc atggcagtta aagattttat gacccgcaag gtagtttata ttagtccaga
     3721 tacaacagta tctcatgcag cagatttgat gagagagcaa ggtttgcacc gtctgcctgt
     3781 tatcgaaaat gatcaattag ttggtttggt gactgaggga accattgcac aagcaagtcc
     3841 atctaaagca acaagtcttt ctatctatga gatgaattat cttctgaata agacaaaagt
     3901 aaaagatgtc atgattcgcg atgttgtcac tgtctcaggc tatgctagtc tagaagatgc
     3961 aacttatctg atgttgaaaa ataagattag tattctccct gtcgtagata accatcaagt
     4021 atacggagtt attactgacc gtgacgtttt ccaagccttt cttgaaattg caggttatgg
     4081 cgaagaaggg attcgtgtac gctttgttac agaagatgaa gttggtgttc ttggaaaaat
     4141 tgtttctttg attgtagaag aaaatttgaa tatctcccat acagtcaata ttccgcgtaa
     4201 ggatggtaag gtgattatcg aagtgcaaat cgatggatca attgatttac cagccttgaa
     4261 agaaaaattt gaagcaaatg gtattcaagt ggaagaaatc gctcgcactt cagcaaaagt
     4321 cttgtaagaa gggaagccca aaggcttctt ttttcatgaa aaggggatta gagcaaaaga
     4381 tggaaagaaa tgataaaata tgctataatg aaataatgta aaaaaggagt atttatggac
     4441 atttcagtaa ttcgtcagaa aattgacgca aatcgtgaaa aattagcttc tttcaggggg
     4501 tctctttgac ctcgaagggc tagaggaaga gattgccatc ttggaaaaca agatgacaga
     4561 acctgatttt tggaacgata atattgcggc ccaaaaaacg tcgcaagaat tgaatgaatt
     4621 aaaaaacact tacaatacct tccataagat ggaagagttg caggatgaag tcgaaatttt
     4681 attggatttt ttggctgaag acgagtcagt gcatgatgaa ctggtagcgc agttagccga
     4741 acttgataag ataatgacca gctacgagat gactctacta ttgtcagaac cttatgacca
     4801 caacaatgcc atcttggaaa tccatccagg ttctggtggt actgaggcgc aggactgggg
     4861 tgatatgttg cttcgtatgt atactcgtta tggtaatgct aaaggcttta aagtggaagt
     4921 gttggattac caagcaggtg atgaggctgg tattaagtcg gtaactttat catttgaagg
     4981 gcctaatgcc tatggtctcc tcaagtcaga aatgggtgtt catcgcttag tgcgaatctc
     5041 accatttgac tctgccaaac gtcgccatac ctctttcaca tctgtagaag tgatgccaga
     5101 attggatgat actattgaag tggaaatccg tgaagatgat atcaagatgg ataccttccg
     5161 ttcaggtggt gccggtggac aaaacgtcaa taaggtttca acaggtgtac gtttaaccca
     5221 cattccaact ggaattgttg tccaatcaac agtggatcgt acccagtatg gaaatagaga
     5281 tcgtgccatg aagatgttgc aggctaagct ctatcaaatg gagcaagata agaaggctgc
     5341 ggaggtagat tctctcaaag gtgagaaaaa ggagatcact tggggaagcc aaatccgttc
     5401 ttatgtcttc acgccttata ctatggtaaa agatcaccga actagctttg aggttgctca
     5461 ggtagataag gttatggatg gggacctaga tggttttatc gatgcttatc tcaagtggcg
     5521 aattagctaa gatagaaagg aactcacatg tcaattattg aaatgagaga tgtcgttaaa
     5581 aaatacgaca acggaacgac tgctctacgc ggtgtttcgg ttagcgttca accgggggaa
     5641 tttgcttaca tcgtaggacc ttcaggagca gggaagtcaa cttttattcg ttctctgtat
     5701 cgtgaagtaa aaatcgataa aggaagtcta tcagttgctg gttttaatct ggttaagatc
     5761 aaaaagaaag atgtcccgct tctacgtcgt agtgttgggg ttgtcttcca agattataaa
     5821 ttgttaccaa agaaaactgt ctatgaaaat attgcttacg ctatggaagt aatcggggaa
     5881 aatcgccgta atatcaaaag acgagtgatg gaagttttgg acttggttgg attgaagcat
     5941 aaggttcgtt ctttcccaaa tgaactctca ggtggggagc agcagcgaat tgcgattgcg
     6001 cgtgcaattg taaataatcc caaagtattg atagctgatg agccaacagg aaatctggat
     6061 ccggataatt catgggaaat tatgaatctc ttggaacgga ttaacctaca agggacaact
     6121 attttgatgg cgactcataa tagccagatt gtaaatacct tgcgccaccg tgtcattgcc
     6181 attgaaaatg gccgtgtcgt tcgtgacgaa tcaaaaggag agtatggata cgatgattag
     6241 tagatttttt cgccatttat ttgaagcctt aaaaagtttg aaacgaaatg gttggatgac
     6301 agtagctgct gtcagttcag tcatgattac tttgaccttg gtggcaatat ttgcatctgt
     6361 tattttcaat acagcgaaat tagctacaga tattgaaaat aatgtccgtg tagtagttta
     6421 tatccgaaag gatgtggaag ataatagtca gacaattgaa aaagaaggtc aaactgttac
     6481 aaataatgac taccacaagg tatatgattc tttgaagaac atgtctacgg ttaaaagtgt
     6541 taccttttca agtaaagaag aacaatatga aaaattaacc gagataatgg gagataactg
     6601 gaaaatcttt gaaggagatg ccaatcctct ctatgatgcc tatattgtag aggcaaacac
     6661 tccaaatgat gtaaaaacta tagccgaaga tgctaaaaaa attgaaggtg tctctgaggt
     6721 tcaagatggc ggtgccaata cagaaagact cttcaagtta gcttcattta tccgtgtttg
     6781 gggactaggg attgctgctt tgttaatttt tatcgcagtt ttcttgattt caaataccat
     6841 tcgtattacc attatttccc gcagtcgcga aattcaaatc atgcgcttgg ttggagctaa
     6901 aaacagttat atccgtggac cgttcttgtt agaaggagcc tttatcggtt tattgggagc
     6961 tatcgcacca tctgttttgg tctttattgt ttatcaaatt gtttaccaat ctgtcaacaa
     7021 atcgttggta gggcaaaatc tatccatgat tagtccagat ttatttagtc cgttgatgat
     7081 tgccctacta tttgtgattg gggttttcat tggttcattg ggatcaggaa tatccatgcg
     7141 ccgattcttg aagatttagg taaaatagct gcttttatga ggagattgta aaatctcctt
     7201 ttttgctaca agagtttttg aaaagagatg cgtagaagaa aagagcttcc aaagaagtcc
     7261 cccagagaag acttcttgat ggctaatttg aacttgaaat ttggcgcact agaaattttt
     7321 tagaaaaaag tgtaattttt ttataaaagc ctttacaaaa aaaattaaag tggtataatt
     7381 aaatcataga aggtgcaaac gttttcgtaa aacgtttgcc taaataaaaa taaaggagat
     7441 ttgaatgatg aaagatacat tcaaaaatgt cttgtctttc gaattttggc aaaaattcgg
     7501 taaggctttg atggtagtta tcgcggttat gccggctgct ggtttgatga tttcaatcgg
     7561 taagtctatc gtgatgatta acccaacctt tacaccactt gtcatcacag gtggaattct
     7621 tgagcaaatc ggttgggggg ttatcggtaa ccttcacatt ttgtttgccc tagccattgg
     7681 aggaagctgg gctaaagaac gtgctggtgg tgctttcgcc gctggtcttg ccttcatctt
     7741 gattaaccgt atcactggta caatttttgg tgtatcaggc gatatgttga aaaatccaga
     7801 tgctatggta actactttct ttggtggttc aatcaaagtt gctgattact ttatcagtgt
     7861 tcttgaagct ccagccttga acatgggggt attcgtaggg attatctcag gttttgtagg
     7921 ggcaactgct tacaacaaat actacaactt ccgtaaactt cctgatgcac tttcattctt
     7981 caacgggaaa cgtttcgtac catttgtagt tattcttcgt tcagcaatcg ctgcaattct
     8041 acttgctgct ttctggccag tagttcaaac aggtatcaat aacttcggta tctggattgc
     8101 caactcacaa gaaactgctc caattcttgc accattcttg tatggtactt tggaacgttt
     8161 gctcttgcca tttggtcttc accacatgtt gactatccca atgaactaca cagctcttgg
     8221 tggtacttat gacattttaa ctggtgcagc taaaggtact caagtattcg gtcaagaccc
     8281 actatggctt gcatgggtaa cagaccttgt aaaccttaaa ggtactgata ctagtcaata
     8341 tcaacacttg ttagatacag tacatccagc tcgtttcaaa gttggacaaa tgatcggttc
     8401 attcggtatc ttgatgggtg tgattgttgc tatctaccgt aatgttgatg ctgacaagaa
     8461 acataaatac aaaggtatga tgattgcaac agctcttgca acattcttga caggggttac
     8521 tgaaccaatc gaatacatgt tcatgttcat cgcaacacct atgtatcttg tttactcact
     8581 tgttcaaggt gctgccttcg ctatggctga cgtcgtaaac ctacgtatgc actcattcgg
     8641 ttcaatcgag ttcttgactc gtacacctat tgcaatcagt gctggtattg gtatggatat
     8701 cgttaacttc gtttgggtaa ctgttctctt tgctgtaatc atgtacttta tcgcaaactt
     8761 catgattcaa aaattcaact acgcaactcc agggcgcaac ggaaactacg aaactgctga
     8821 aggttcagaa gaaaccagca gcgaagtgaa agttgcagca ggctctcaag ctgtaaacat
     8881 tatcaacctt cttggtggac gtgtaaacat cgttgatgtt gatgcatgta tgactcgtct
     8941 tcgtgtaact gttaaagatg cagataaagt aggaaatgca gagcaatgga aagcagaagg
     9001 agctatgggt cttgtgatga aaggacaagg ggttcaagct atctacggtc caaaagctga
     9061 cattttgaaa tctgatatcc aagatatcct tgattcaggt gaaatcattc ctgaaactct
     9121 tccaagccaa atgactgaag cacaacaaaa cactgttcac ttcaaaaatc ttactgagga
     9181 agtttactca gtagcagacg gtcaagttgt tggtttggaa caagtaaagg atccagtatt
     9241 tgctcaaaaa atgatgggtg atggatttgc agtagaacct gcaaatggaa acattgtatc
     9301 tccagtttca ggtactgtgt caagcatctt cccaacaaaa catgcttttg gtattgtgac
     9361 ggaagcaggt cttgaagtat tggttcacat tggtttggac acagtaagtc ttgaaggtaa
     9421 accatttaca gttcatgttg ctgaaggaca aaaagttgca gcaggagatc tccttgtcac
     9481 agctgacttg gatgctatcc gtgcagcagg acgtgaaact tcaacagtag ttgtcttcac
     9541 aaatggtgat gcaattaaat cagttaaatt agaaaaaaca ggttctcttg cagctaaaac
     9601 agcagttgct aaagtagaat tgtaatatac ttgaggttgg aagctgtatt ccaacctctt
     9661 attttgggag aaaagaatga aatttttaac actcaatact cacagttgga tggagaaaga
     9721 agcagaggaa aaattccaga ttttgcttga agatattctt gaaaaggact atgatttgat
     9781 ttgtttccaa gaaatcaatc aggagatgac ctcgtcagag gtggaggtta atgaccttta
     9841 tcaagctttg ccagcagctg agcctattca ccaagaccat tatgttagac tcttggttga
     9901 aaagttgtta gagcaaggga aaaattacta ctggacctgg gcttataacc atatcggcta
     9961 tgaccgctac cacgaaggtg tggctatctt gtctaaaaca cctattgaag ccagagaaat
    10021 tttggtttca gatgtggatg atccaacaga ctatcatact cgccgtgttg ccctagctga
    10081 aactgtagtc gatggcaagg agctagcagt tgccagtgtt catctctctt ggtgggataa
    10141 aggttttcaa gaagaatggg cacgatttga ggctgtcttg aaaaaattga acaagccact
    10201 tttactagct ggagatttta acaacccagc aggtcaggaa ggttaccaag ctattttagc
    10261 tagtccatta ggcttacaag acgcatttga agttgctcaa gagaaaagtg gtagctatac
    10321 tgttccgcct gaaattgatg gctggaaagg gaacactgaa ccccttcgaa tcgattatgt
    10381 ctttactacc aaagagttag cggtggaaaa tttacatgtc gtatttgatg gtaacaagag
    10441 tccacaagtg agtgatcact atggcttgaa tgctatatta aactggaaat aataactgaa
    10501 aagaggttgg aactataaaa ttccagcctt ttcttactag agaagctact ggaaatagcc
    10561 taaataagtg agactactgt aatggaataa aatatggtat aattgataag atagatagaa
    10621 tcgaggatgt tatgtcattt acgaaatttc aatttaaaaa ctatattaga gaagccttga
    10681 aggagttaaa atttacaact ccaacagagg tgcaagacaa gttgattcct attgttttgg
    10741 caggtcgtga cctagtagga gaatcaaaaa caggttcagg taagactcat actttcttgt
    10801 taccgatttt tcagcaatta gatgaagcta gcgatagtgt acaagcagtg attactgcac
    10861 cgagtcgtga gttggctact caaatttacc aagtagcgcg tcagatttca gctcactcag
    10921 atgtcgaagt tcgtgtggtt aattatgtgg gtggtacgga taaggctcgc cagattgaga
    10981 aattggcaag caatcagcct catattgtta ttggaacacc aggccgtatc tacgacttgg
    11041 ttaaatctgg tgatttagct attcataaag ccaagacatt tgttgttgat gaagcagata
    11101 tgaccttgga tatgggattc ttggaaactg ttgataagat tgctgacagt cttccaaaag
    11161 acttgcaatt catggtcttc tcagcgacta tcccacaaaa actgcaacca ttcttgaaaa
    11221 aatacttatc aaatcctgtt atggagaaaa ttaagaccaa aacggttatt tctgacacca
    11281 ttgataattg gttgatttcg accaagggac atgataagaa tgctcaaatt taccagttga
    11341 ctcagtcgat gcagccgtat ttggcaatga tttttgttaa cactaaaacg cgtgctgatg
    11401 aattgcattc atatctgact gctcaaggct tgaaggttgc aaaaatccat ggcgatattg
    11461 cccctcgtga acgcaagcga atcatgaatc aggtgcaaaa tctggatttt gagtatattg
    11521 tcgcaacaga tttggcagca cgtgggattg acattgaagg tgtcagccat gtcatcaatg
    11581 atgccattcc gcaagactta tctttttttg ttcaccgtgt tggtcgtact ggacgaaatg
    11641 gcctaccagg tacagctatt accctttatc agccaagtga tgactcggat atccgtgagt
    11701 tggagaaatt gggaatcaag tttagtccta agatggtcaa agacggggaa tttcaagata
    11761 cctatgaccg tgatcgtcgt gccaaccgtg agaaaaaaca agataaactt gatatcgaaa
    11821 tgattggttt ggttaaaaag aaaaagaaaa aagtcaaacc gggttataag aagaaaattc
    11881 aatgggcggt tgatgaaaag cgccgtaaaa ccaagcgtgc tgaaaatcgc gctcgcggtc
    11941 gtgcagagcg taaagctaaa cgccaaacat tttaatagaa attgttggag tactgagctc
    12001 caactttttt atttatgaga acgaactatc taaaccgaaa cactacatta aagactgcaa
    12061 attgcgatta aaaatggtat aatgataaag ttatatagtc ccgataagat ggtaggtatt
    12121 tattacgaag agttttccta tcagtagttt gcaattcgca aagaatgacg gcttcgaggt
    12181 cgctcgtctt tctacggttg ccgccatact gcggtcaccc tatgcgcctt actagcttca
    12241 gaaataaaaa agtatcgttt ttatttctga agctagtaac tcttagataa tggaaattcc
    12301 tatcagtact ttgtaactct ataacaatat tttttaaggg gggacatttt tatgtcagaa
    12361 cgtaaattat tcacgtctga atctgtatct gaggggcatc cggataagat tgcagaccaa
    12421 atttcagatg cgattttgga tgctatttta gcaaaggatc cagaggcgca cgttgctgct
    12481 gaaacagctg tatatactgg ttctgtccac gtttttggtg aaatttctac aaatgcctat
    12541 gtggatatta accgtgtggt tcgtgatacc attgcagaga ttggttatac caatacagaa
    12601 tatggatttt ctgctgagac ggtgggagta cacccatctt tggtggaaca atctcctgac
    12661 atcgctcaag gtgttaacga agccttggag gttcgtggaa atgctgatca agatccactg
    12721 gacttgattg gagcaggtga ccaagggctc atgtttggat ttgcagtaga tgaaacagaa
    12781 gagttcatgc cattgccaat tgcactcagt cataaattgg ttcgtcgtct ggcagaactt
    12841 cgtaagtctg gagaaattag ctatctccgt ccagatgcaa aatcacaagt tacagttgag
    12901 tacgatgaaa atgaccgtcc ggtacgtgta gatacagtcg ttatttctac tcagcatgat
    12961 ccagaggcca ctaatgaaca aatccatcaa gatgtgattg acaaggtcat caaagaagtt
    13021 attccatctt cttatcttga tgataaggca aaattcttta tcaatccgac aggtcgtttt
    13081 gtaatcggtg gtcctcaagg ggactcaggt ttgactggtc gtaagattat tgtagatact
    13141 tatggtggct actctcgtca tggtggtggt gccttctctg gtaaagatgc gactaaggtg
    13201 gatcgttcag cctcttatgc ggctcgctat attgccaaga atatcgttgc agcaggcctt
    13261 gctaagaagg cagaagtgca gttggcctat gctatcggtg ttgcgcaacc tgtttctgtt
    13321 cgtatcgata ctttcggtac aggaacagta gctgaaagtc aacttgaaaa agcggctcgt
    13381 caaatctttg accttcgccc tgcagggatt atccaaatgc tggacctcaa gcgtccaatt
    13441 taccgtcaaa catcggctta cggtcacatg ggacgtacag atattgatct tccatgggaa
    13501 cgtttggata aggtagatgc tttgaaagaa gcagtaaaat aagattttaa gaggggaacg
    13561 tcctctcttt tttatagttt ttaactatac tgggatactg ttctgaaaat ccattttgcg
    13621 aaagtagaga tttacatgta taatggattg aaactagaat agtacacctc aacttctaaa
    13681 acattgttag aaatcgattt gactgtcctg atcgatttct cctgttcttg tttcatttta
    13741 ctatatttct ttaaaaatga taaaggttga gatttctcct cgtaatagat aatcatgggg
    13801 atatttcaag ccaaagtttt attcgttatc acttgactat tgcaaggttt tctagatcaa
    13861 cagagtcatg gaatggactc atggttgaga tttctccttg ttgcttggac ttcattcaaa
    13921 agtctgttac ccaagccttg ttcaaacttc caatacacta gctgtttcca tagcatgact
    13981 tctgtactag actttctttt ccgaataaat agatagaacc acagaatcta gtaaacctag
    14041 aattaaaatt atggtataat attagcaata aaagaaatct ggaggattag aatcatggta
    14101 tcaacgaaaa cacaaattgc tggttttgag tttgacaatt gcttgatgaa tgcagcaggt
    14161 gtggcttgta tgacgataga ggagttagaa gaggtcaaaa actcagcggc aggaaccttt
    14221 gttactaaga cagcgacctt ggacttccgt caggggaatc ctgagccacg ctaccaagat
    14281 gttccacttg gttccatcaa ctctatgggc ttgccaaata atggcttaga ctattatttg
    14341 gattatcttt tagatttgca ggaaaaagag tcgaaccgaa ctttcttctt atctctggtc
    14401 ggcatgtctc cagaggaaac ccatactatt ttgaaaaaag tccaagagag tgattttcgt
    14461 ggtctgactg agctaaatct ttcctgtcca aatgttccag gtaaacctca gattgcctat
    14521 gattttgaga caacagaccg gattttggca gaagtgtttg cttacttcac caaacctctt
    14581 ggaattaaat tgccacctta ttttgatatt gttcactttg atcaagcggc agctattttc
    14641 aacaaatatc cgctcaagtt tgtcaactgc gttaactcta tcggaaacgg cctctatata
    14701 gaagacgaat ctgtcgttat tcggcctaag aatggttttg gtggaattgg tggagaatac
    14761 atcaaaccga ctgctctagc caatgttcac gccttttatc aacgtttaaa tcctcaaatc
    14821 caaattatcg gaacaggtgg cgttctgact ggtcgagatg cctttgaaca catcctctgt
    14881 ggagcaagta tggtgcaggt gggaacgacc cttcacaaag aaggcgtcag tgcttttgac
    14941 cgcattacca atgaactgaa agcaatcatg gtggaaaaag gctacgagag cttagaagat
    15001 ttccgtggga aattgcgcta tattgactaa attaaatcaa aaaatctgaa gaaaggagag
    15061 acgatgctag ccattgaaga aagtcagaag ttgactttat caaatttacc gagcctgagc
    15121 ctatttacag ggacagatca gggtcagttt gaagtgatga agagtcaaat gttgaaacag
    15181 attgggtatg attctgctga cctcaacttt gcctactttg atatgaaaga agtagtttac
    15241 aaggatgtgg aactggagtt ggtcagcctt cctttctttg cggatgagaa aatcgtgata
    15301 ttagattatt ttatggatat cacgactgct aagaaacgct ttttgacaga tgatgagctt
    15361 aagtcatttg aggaatacct tgacaatcct tctccaacaa ccaagttgat aatctttgca
    15421 gaaggaaagc tggatagcaa aagacggtta gtcaaattac ttaagcgtga tgccaaggtc
    15481 ttcgatgcag tagaagtaaa agaacaagaa ttgcgccagt atttccaaaa gtggagtcag
    15541 aaacaaggtc tgcagtttac caatcattct tttgaaaatc tcctcatcaa gtcggggttt
    15601 caatttagcg aaatccagaa aaatcttctc tttttacagt cctataaggc gaattctgtt
    15661 attgaggaag aggatattgt taacgcaatt cccaagacct tgcaggacaa tatttttgat
    15721 ttaactcagt ttattctgac taaaaagatg gatcaggcgc gcgatttggt gagagacttg
    15781 accttgcaag gggaagatga aatcaaactg attgcagtca tgctgggaca atttcggact
    15841 tttactcagg tgaagatttt ggcggagtct ggccaaacag aatcgcagat tgcaagtagt
    15901 ttaggtagtt atctgggacg taacccaaat ccttatcaaa tcaagtttgc attaagagat
    15961 tcgagaggac tttctttgag ctttctgaag caagctattt cctatttgat tgagacagac
    16021 tatcagatta agacaggtct ttatgaaaaa ggtttccttt ttgaaaaggc actcttacag
    16081 attgctagtc aggtcaattg acatttgttg aaactacaac ccgcgtcagg attatcttgt
    16141 cgtgggtttc ttgctgattt gcttatttta ttagaaagta tgtcagtgat ttccttatct
    16201 ataagcaaaa aacttgaaaa aagtgaatgt ttgcgttatc attttcatat agaaagaaaa
    16261 agaggtatta cagatggcta ttatcttacc agaacttcca tatgcatacg acgctttgga
    16321 accatacatc gatgcggaaa caatgcattt gcaccatgac aaacaccatc aaacttatgt
    16381 caacaatgcc aatgcagctt tagaaaaaca ccctgaaatc ggtgaagacc ttgaagcctt
    16441 gcttgctgat gtagaatcta tcccagctga tatccgtcaa gcacttatca acaatggtgg
    16501 cggacacttg aaccacgctc ttttctggga attgatgact cccgagaaaa cagctccttc
    16561 agcagaactg gcagcagcaa tcgatgcaac atttggttca tttgaagaat tccaagcagc
    16621 cttcactgca gcagcaacaa ctcgttttgg ttcaggttgg gcatggttgg ttgtcaacaa
    16681 agaagggaaa cttgaagtga cttcaacagc aaaccaagac acaccaatct cagaaggtaa
    16741 aaaaccaatc ttgggcttgg acgtttggga acatgcttac tacgtgaaat accgcaacgt
    16801 gcgtcctgac tacatcaaag ctttcttttc agtaatcaac tggaataaag tagatgaatt
    16861 gtacgcagct gctaaataat gatagttgga gggaagaatt gttcttctct ttttaggtta
    16921 taagattctg gtctgacaaa atcgtcagac ttttttcatt tttatgagaa acgtgctaac
    16981 tgctagaaat tatggtagaa taaagtatta agtaatcgtg gaaaaaggat atctatgcga
    17041 aaagaaattg cacctgaatt atacaactat aacaagtttc ctggtccgga gttccattta
    17101 cacggggata aggtcgaaac ggaagggata gctttttcct tggttgaaaa tatcaaggat
    17161 gcctttgatg tgacgacttt taatcagcgt ttttcagaag tcttaaccaa gtttgattat
    17221 atcgtggggg actggagcaa cgaacagctt cgcctacgag gtttttacaa ggatgaccga
    17281 acagaagaaa aacttgaaaa aatcagtcgt ttacaagact accttttaga gtattgtagt
    17341 tatggttgtg cctattttgt cttagaaaat gaagccccta agcgagcatc atttgacaag
    17401 aaaatgcgta agacggaaga agaaacacct tctagaaaag gaaagaaacc gactcaaact
    17461 aaacgaaagt cgaatgcaga taagaaaaat agacgtcgtc agaaagacca gcattctcag
    17521 aaagaggaca aggaacaacg tcattttgtc attcgtcaga agtgagtaga gaataaggag
    17581 aagaaatgaa accctcaatt catagtttga cacatcaaac catgcaggaa tgggtattgg
    17641 agcagggaga aaagaaattc cgtgcagatc aaatctggga atggctctac cgtaaacgtg
    17701 tgcagtcatt tgaagaaatg accaaccttt ccaaggattt gattgctaag ctcaatgacc
    17761 agtttgtggt caatcccttg aaacaaggta ttgtgcaaga gtctgctgat ggtacagtca
    17821 aatatctctt tgaattgcct gacggtatgt taattgagac tgtactcatg tgtcaacact
    17881 atggtttatc tgtctgtgtg accactcagg tcggctgtaa tatcggttgt accttctgtg
    17941 cctctggttt gattaagaag cagcgtgacc tcaataacgg tgaaatcgta gcgcaaatca
    18001 tgctggttca gaaatacttt gatgagcgtg gtcaggatga acgcatcagc catatcgttg
    18061 tcatgggaat cggtgagccc tttgataatt acaacaatgt cttgaatttc tttcgtacta
    18121 tcaatgatga taaaggaatg gctatcggtg ctcgtcacat cacggtttca atctcaggtt
    18181 tggctcataa aattcgtgac tttgctgatg aaggggttca ggtcaatctt gccgtgtctc
    18241 ttcacgcacc caacaatgaa cttcgttcaa gtatcatgaa gattaaccgt gcctttccga
    18301 ttgaaaaact ctttgctgct attgaatact acattgagac aacaaaccgt cgtgtaacct
    18361 ttgaatatat catgcttaat gaagtcaacg acggtgtgga acaagccttg gaattggctg
    18421 aattgctcaa gaacatcaag aaatcgtctt atgtaaactt gattccttat aacccagtta
    18481 gtgagcatga ccaatatagc cgtagtccca aagagcgcgt gttggctttc tatgatacgc
    18541 ttaagaaaaa agggggcaac tgtgtggttc gtcaagagca tggtacagat attgacgcag
    18601 cttgtggaca attgctcttt aacacaatga aacgtgaccg ccagaaggca gtcgcagcgg
    18661 taaatcctta atgatgaaga agacttataa tcatattttg gtctggggag tcattttcta
    18721 tagcatttgc attgtctatt tttgctttac tcctcaagaa caatctaccg tgggagtggg
    18781 aactccagat attcagcatc ttggacgcct ggtttttctt ttgactcctt tcaattctct
    18841 ctggaaactg ggcgaagtga gtgacattgg acaattatgt tggatttttt tacaaaatat
    18901 cctcaatgtc ttcttgtttt ttcctctgat tttccaactc ctttatctat ttccaaattt
    18961 gcggaaaaca aaaaaggtcc ttctttttag ttttcttgtg agtcttggaa tcgagtgtac
    19021 gcaattaatc ttggactttt tctttgattt caatcgcgtc tttgagattg atgatttgtg
    19081 gaccaacact ttgggtggct atctggcttg gctcctttat aaacgattac ataaaaacaa
    19141 gataaggaat taaaatgagt attttagaag ttaaaaatct gagtcacggt tttggtgacc
    19201 gtgcaatttt tgaagatgtg tccttccgtc tcctcaaggg ggaacatatc ggcctggtcg
    19261 gtgccaatgg tgaaggaaaa tcaaccttta tgagtatcgt gactggtaaa atgctgccag
    19321 atgaaggaaa ggttgagtgg tccaaatatg tgacggctgg ttacttggat cagcactctg
    19381 tccttgctga aagacagtcg gtgcgtgatg ttctccgtac ggcttttgat gagcttttca
    19441 aagctgaagc tcgtatcaat gacctctata tggaaatggc tgaagacggt gcggatgttg
    19501 atgctctcat ggaagaagta ggagaacttc aagaccgtct ggagagtcgt gatttctata
    19561 ccttggatgc taagattgac gaagtagcgc gtgctcttgg tgttatggac tttggcatgg
    19621 atacggatgt aacttctttg tcaggtgggc aaagaaccaa ggtgcttttg gcaaaacttc
    19681 tccttgaaaa gcctgatatc ttgctgttgg acgagccgac caactacttg gatgctgagc
    19741 atattgattg gctcaagcgc tatctccaaa actatgagaa tgcctttgtt ctcatttcgc
    19801 acgatattcc attcctcaat gacgttatca atattgtcta tcatgtggaa aatcaacagc
    19861 tgacgcgtta ctctggtgac tactaccagt tccaagaagt ttatgctatg aagaaatctc
    19921 agctagaggc agcctacgaa cgccagcaga aagagattgc agacctcaag gactttgtgg
    19981 ctcgtaataa agcccgtgtt gcaactcgta atatggctat gtctcgtcaa aagaaattgg
    20041 ataagatgga tattatcgaa ctccaaagtg agaaaccaaa accatccttt gatttcaaac
    20101 cagctcgtac accagggcgc tttatcttcc aaaccaagaa cttgcaaatt ggttacgacc
    20161 ttcctcttac taagccttta aatcttacct tcgaacgcaa tcaaaaggtt gcgattattg
    20221 gtgctaatgg tattggaaaa acaactctct tgaagagtct cttgggcatt atctcgccaa
    20281 tcgctgggga agtggagcgt ggagattatt tagaacttgg ttattttgag caggaagtag
    20341 aaggcggtaa tcgccaaact cctcttgaag ctgtctggaa tgcctttcct gcccttaatc
    20401 aagcagaagt ccgtgcagcc cttgcccgtt gtggtttgac aaccaaacat attgaaagcc
    20461 agattcaagt attatcaggg ggagagcaag ccaaggttcg tttctgtctc ttgatgaatc
    20521 gtgaaaacaa cgttttagtg ctggacgagc cgaccaacca tttggatgtg gatgcaaagg
    20581 atgagctcaa acgcgctctc aaagaatata ggggatctat ccttatggtc tgccacgagc
    20641 cagactttta tgaaggctgg atagaccaaa tatgggattt taataattta acttaagaat
    20701 gagagtaaaa gaaatacagt accgaatgtg gatactgtat ttttttggtt tttaagattt
    20761 aaaatcgtag tctttcacca cttcgatgct gtcgattgtg atagcagtag ttggcttgtc
    20821 tttttcatct ttttcggcct tagcaatctt atccacaaca tccataccgt caatcacttg
    20881 accaaagact gggtgtttgc catctagact agggtttcca ccttctttgt aggcttcgat
    20941 aattttctgt ggatacttgc ttgtagggag tttagaagag gtatctgtag agctttggtt
    21001 gatgaagaac tggctgccat tggtgtttgg ttgaccagta ttagccatag caagagcacc
    21061 acggatgtta tacaaataag gagtaatctc gttcttgaaa ccagttcctt tgtctttagt
    21121 cttatccttg tcatgccaga tggactgacc acctgtaccg tccccttttg gatctccagt
    21181 ttggaccata aagccatcga tgacacggtg gaaggtaata ccgttatagt agccttcttt
    21241 ggcgtgagtg aggaaatttt caaccgctag aggagcgagt ttagggaaga gtttaatgcg
    21301 aatatcacct tggcttgtgt ggagaatcac ttcggcttca tcttcagcaa cttccttaga
    21361 tagttgtggg aaattggcgt tttcgtttgt taaagcatcg tttaactcct tggcagattg
    21421 ggcagctact ttggaacttt cttcagcagc aagactggaa tcaacataat catcaccacg
    21481 cagactgcgt tggacgctgc tacacccagc tagggctaca gtagacagta aaagaagggt
    21541 tgctagtttt ttcattctga tcctctcaaa aattcattta taccattgta ccctaaaaag
    21601 aagtggattt caaatattag tagtttacag aactggctta gataatagtt gggatttcat
    21661 catcatcttg aaaatcttca acttcttcaa cttcttcccc agtaaatggt ttctgaaaag
    21721 aacttagtat aaaacgggca attggttcaa caattaggaa atttagagga agagctgcaa
    21781 taaagtttac gaaccaggcg cttagatagg tattgggtgt gatagcaatg ccattgtaaa
    21841 aaagtccata gaaggacatg aaagtgacca gctaattctt cttctgaaaa atgctcatga
    21901 agggcttgat ccaggtcgca agatttcatt ttagaaagtc cagtaactcc cttcttcttc
    21961 aggatattct ttttcatggt attatttaga tggtcaagtg agtcaaaaga agtttcgaca
    22021 agagcatacc ctttttctat cagagttttt agatgtttag gggcatcaat accataagtg
    22081 tactcaaagt attttggaaa ccagatctta agaaagctcg taaagctagc cagttctcta
    22141 aacgctaaga actagctaca acacagcatt tacaacactt catggttcac accatggggt
    22201 gctttttaat gattttaagc aaaattcaca cttaattgaa agttatttaa attagatgaa
    22261 aatttatttt ttgaaaaagc gggaaaacat tgattctaag cgaattttga atcatattcg
    22321 aatgggagtt tttaaaatca tgtttcagtg gtaaaagtac caaactggat tctccatagt
    22381 aaaatgatat ctcctgctag tgaatcatct actaataagt ccatatttcg cttgggaacg
    22441 ggcttgggac ttagaagcca agtatccaac tctcgttcag gcgatatgaa gggtttgact
    22501 tggtgttctt tataaaattt ttctaaaata gtattcacgg atagcatctt tcaaacattt
    22561 atttcctatt ctaacaaatt tctaaatact ttaagaaatt tatagtctgt caagtttttt
    22621 tcttgacaca tgccagaaat ctgctataat agaacatgtg ctaaatagct cagctatttc
    22681 accgaaataa aaaattaaag aaatgagact ttaaaaatgg cagttaaaat ccgtttgact
    22741 cgtatgggtt ctaagaaaaa acctttctac cgtatcaacg tagcagattc acgttcacca
    22801 cgtgacggac gtttcatcga aacagttgga acttacaacc cacttgttgc tgaaaaccaa
    22861 gtaactttga aagaagaccg cgttcttgca tggttggcta atggagctca accttcagac
    22921 acagtacgta acatcctttc aaaagaaggc gtattgaaaa aattccacga ttctaaattc
    22981 tcaaaataag tttaaagtag gttgacagat ggatacgatt gaaaatctca ttattgcgat
    23041 tgtgaaaccc ttaatttcac aaccagatgc cttaactatc aagattgagg atacaccaga
    23101 atttttggaa tatcatttga atcttgatca aagcgatgtg ggtcgtgtaa tcggtcgtaa
    23161 gggtcgcact atttctgcga taagaacgat tgtctactct gtcccaactg aatacaaaaa
    23221 agtaagaatc gttattgacg aaaaataaga agggcgggac ggatgtctcg cttttttgtg
    23281 tggaatagaa g
//
LOCUS       DAVBOD010000027        22635 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 640-05
            SAMEA1012484-rid20186543.denovo.027, whole genome shotgun sequence.
ACCESSION   DAVBOD010000027 DAVBOD010000000
VERSION     DAVBOD010000027.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012484
            Sequence Read Archive: ERR059358
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 22635)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22635)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979948.1
            Genome Coverage       :: 595x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:03:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,266
            CDSs (total)                      :: 2,219
            Genes (coding)                    :: 2,091
            CDSs (with protein)               :: 2,091
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 71 of 128
            Pseudo Genes (incomplete)         :: 50 of 128
            Pseudo Genes (internal stop)      :: 33 of 128
            Pseudo Genes (multiple problems)  :: 22 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22635
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012484-rid20186543.denovo.027"
                     /strain="NIG 640-05"
                     /db_xref="taxon:1313"
     gene            complement(339..1319)
                     /locus_tag="VQ862_001182"
     CDS             complement(339..1319)
                     /locus_tag="VQ862_001182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetylxylan esterase"
                     /protein_id="HET3115538.1"
                     /translation="MKNPALLEEIKTYRGRDEVPEDFDAFWDGEVKNVSTLPSYHLEE
                     RDFHIPQVKCYELTFEGSKEGKVYARIVLPKSEEKVPLIFHFHGYMGRGWDWADMLGF
                     TVAGYGVVSMDVRGQSGYSQDGLRSPLGNTVKGHIIRGAMEGRDHLFYKDVYLDIYQL
                     VEIVASLSQVDEKRLSSYGASQGGALALVAAALNPRIQKTVAIYPFLSDFRRVIEIGN
                     TSEAYDELFRYFKFHDPFHETEEEIMATLAYIDVKNLAHRIQGEVKMITGLDDDVCYP
                     ITQFAIYNRLTCDKTYRIMPEYAHEAMNVFVDDQVYNWLCGSEIPFKYLK"
     gene            complement(1635..3650)
                     /gene="recG"
                     /locus_tag="VQ862_001183"
     CDS             complement(1635..3650)
                     /gene="recG"
                     /locus_tag="VQ862_001183"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001048793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecG"
                     /protein_id="HET3115539.1"
                     /translation="MNLHQPLHVLPGVGPKSAEKYAKLGIENLQDLLLYFPFRYEDFK
                     TKQVLELEDGEKAVLSGQVVTPASVQYYGFKRNRLRFSLKQGEVVFAVNFFNQPYLAD
                     KIELGATLAVFGKWDRAKASLTGMKVLAQVEDDLQPVYRLAQGISQASLVKVIKTAFD
                     QGLDLLIEENLPQSLLDKYKLMSRCQAVRAMHFPKDLAEYKQALRRIKFEELFYFQMQ
                     LQMLKSENRVQGSGLVLNWSQEKVTAVKVSLPFALTQAQEKSLQEILTDMKSDHHMNR
                     LLQGDVGSGKTVVAGLAMFAAVTAGYQAALMVPTEILAEQHFESLQNLFPNLKLALLT
                     GSLKAAEKREVLETIAKGEADLIIGTHALIQDGVEYARLGLIIIDEQHRFGVGQRRIL
                     REKGDNPDVLMMTATPIPRTLAITAFGDMDVSIIDQMPAGRKPIVTRWIKHEQLPQVL
                     TWLEGEIQKGSQVYVISPLIEESEALDLKNAIALSEELTTHFAGKAEVALLHGRMKSD
                     EKDQIMQDFKERKTDILVSTTVIEVGVNVPNATVMIIMDADRFGLSQLHQLRGRVGRG
                     DKQSYAVLVANPKTDSGKDRMRIMTETTNGFVLAEEDLKMRGSGEIFGTRQSGLPEFQ
                     VADIIEDFPILEEARKVASYISSIEAWQEDPEWRMIALHLEKKEHLD"
     gene            complement(3669..4772)
                     /locus_tag="VQ862_001184"
     CDS             complement(3669..4772)
                     /locus_tag="VQ862_001184"
                     /EC_number="5.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000648075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HET3115540.1"
                     /translation="MKASPHRPTKALIHLGAIRQNIQQMGAHIPQGTLKLAVVKANAY
                     GHGAVAVAKAIQDDVDGFCVSNIDEAIELRQAGLSKPILILGVSEIEAVALAKEYDFT
                     LTVAGLEWIQALLDKEVDLTGLTVHLKIDSGMGRIGFREASEVEQAQDLLQQHGVCVE
                     GIFTHFATADEESDDYFNAQLERFKTILASMKEVPELVHASNSATTLWHVETIFNAVR
                     MGDAMYGLNPSGAVLDLPYDLIPALTLESALVHVKTVPAGACMGYGATYQADSEQVIA
                     TVPIGYADGWTRDMQNFSVLVDGQACPIVGRVSMDQITIRLPKLYPLGTKVTLIGSNG
                     DKEITATQVATYRVTINYEVVCLLSDRIPREYY"
     gene            complement(4762..5130)
                     /locus_tag="VQ862_001185"
     CDS             complement(4762..5130)
                     /locus_tag="VQ862_001185"
                     /EC_number="2.7.8.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000061844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="holo-ACP synthase"
                     /protein_id="HET3115541.1"
                     /translation="MRMIVGHGIDIEELASIESAVTRHEGFAKRVLTAQEMERFTSLK
                     GRRQIEYLAGRWSAKEAFSKAMGTGISKLGFQDLEVLNNERGAPYFSQAPFSGKIWLS
                     ISHTDQFVTASVILEENHES"
     gene            complement(5169..6200)
                     /locus_tag="VQ862_001186"
     CDS             complement(5169..6200)
                     /locus_tag="VQ862_001186"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HET3115542.1"
                     /translation="MAFIEKGQEIDMEVIKAETQLSAEALRLKESRDRELADIISGED
                     DRILLVIGPCSSDNEEAVLEYARRLSALQKKVADKIFMVMRVYTAKPRTNGDGYKGLV
                     HQPDTSKAPSLINGLQAVRQLHYRVITETGLTTADEMLYPSNLILVDDLVSYHAVGAR
                     SVEDQEHRFVASGIDAPVGMKNPTSGNLGVMFNAIYAAQNKQTFLYHGQEVETSGNPL
                     AHVILRGAVNEYGNYMPNYYYENLLQAIERYETMGLENPFILIDTNHDNSGKQYMEQI
                     RIVRQTLQNRDWNEKIKKTVRGFMIESYLADGRQNQPEIFGCSITDPCLGWENTEALV
                     EEIYVTLTK"
     gene            complement(6202..7233)
                     /locus_tag="VQ862_001187"
     CDS             complement(6202..7233)
                     /locus_tag="VQ862_001187"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000232189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HET3115543.1"
                     /translation="MVFTAKSSKINIEEVRALSKLEGQALERKSQRDQELEAIIRGED
                     QRILLVIGPCSSDNEEAVLEYAKRLAVLQEEVADRIFMVMRVYTAKPRTNGDGYKGLI
                     HQPNATEAPSLINGIKAVRHLHYRVITETGMTTADEMLYPENLPLVDDLISYMAVGAR
                     SVEDQQHRFVASGAGFSTGFKNPTSGNLNVMFNGIYAAQNKQSFLFLGKEVETTGNPL
                     SHAILRGALNEYGKNIPNYYYDNLIDTIAQYEKMGLENPFIIIDTNHDNSGKQYIEQI
                     RIVRQTLINRAWNEKIKQFVRGFMIESYLEDGRQNEPEVFGKSITDPCLGWDNTEALV
                     REIYKTLGE"
     gene            complement(7314..9827)
                     /gene="secA"
                     /locus_tag="VQ862_001188"
     CDS             complement(7314..9827)
                     /gene="secA"
                     /locus_tag="VQ862_001188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecA"
                     /protein_id="HET3115544.1"
                     /translation="MANILKTIIENDKGEIRRLEKMADKVFKYEDQMAALTDDQLKAK
                     TVEFKERYQNGESLDSLLYEAFAVVREGAKRVLGLFPYKVQVMGGIVLHHGDVPEMRT
                     GEGKTLTATMPVYLNALSGKGVHVVTVNEYLSERDATEMGELYSWLGLSVGINLATKS
                     PMEKKEAYECDITYSTNSEIGFDYLRDNMVVRAENMVQRPLNYALVDEVDSILIDEAR
                     TPLIVSGANAVETSQLYHMADHYVKSLNKDDYIIDVQSKTIGLSDSGIDRAESYFKLE
                     NLYDIENVALTHFIDNALRANYIMLLDIDYVVSEEQEILIVDQFTGRTMEGRRYSDGL
                     HQAIEAKEGVPIQDETKTSASITYQNLFRMYKKLSGMTGTGKTEEEEFREIYNIRVIP
                     IPTNRPVQRIDHSDLLYASIESKFKAVVEDVKARYQKGQPVLVGTVAVETSDYISKKL
                     VAAGVPHEVLNAKNHYREAQIIMNAGQRGAVTIATNMAGRGTDIKLGEGVRELGGLCV
                     IGTERHESRRIDNQLRGRSGRQGDPGESQFYLSLEDDLMKRFGSERLKGIFERLNMSE
                     EAIESRMLTRQVEAAQKRVEGNNYDTRKQVLQYDDVMREQREIIYTQRYDVITADRDL
                     APEIQSMIKRTLERVVDGHARAKQDEKLEAILNFAKYNLLPEDSITMEDLSGLSDKAI
                     KEELFQRALKVYDSQVSKLRDEEAVKEFQKVLILRVVDNKWTDHIDALDQLRNAVGLR
                     GYAQNNPVVEYQAEGFRMFNDMIGSIEFDVTRLMMKAQIHEQERPQAERHISTTATRN
                     IAAHQASMPEDLDLSQIGRNELCPCGSGKKFKNCHGKRQ"
     gene            complement(9973..10263)
                     /locus_tag="VQ862_001189"
     CDS             complement(9973..10263)
                     /locus_tag="VQ862_001189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000940707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3115545.1"
                     /translation="MAHLKSFITRYSKVYIGLVLLIWIAFFFLPWGSPILGGGKIDLF
                     SIQKVLLVFGILSILMALLSKKVSLFVFGLICCLSLWINLFILFAILPILGN"
     gene            complement(10291..10923)
                     /locus_tag="VQ862_001190"
     CDS             complement(10291..10923)
                     /locus_tag="VQ862_001190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001235275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HET3115546.1"
                     /translation="MRLEIINGQKIYGKRPILNQLNLVFQSGKIYGLKGDNGSGKTVL
                     LKILAGYIKLDKGKVLQDGKVYGIKNHYIQDAGILIEKVEFLSHLSLRENLELLRYFS
                     SKVTEKRIAYWIQYYDLQEFEDVEYRHLSLGTKQKMALIQAFISSPSILFLDEPMNAL
                     DEKSVRLTKQVILSYLKKENGLVILTSHISEDISDLCTDVLVVENGHIQM"
     gene            complement(10927..11568)
                     /locus_tag="VQ862_001191"
     CDS             complement(10927..11568)
                     /locus_tag="VQ862_001191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000475766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3115547.1"
                     /translation="MFKNFNNIWLKRKIVLLLRIVLMMILINYLLSTAVQKQDAVIFF
                     KRELISIFSYNDYSEANLEIPKLLLNLSLFMVGWLSVILLESDLADHYHHLIRYQSSS
                     FFDYTRKRLVVISKFFTQDLFVWFLGLLPLGIHFKTVALFFLLAQLMMLYLLLSYLIA
                     LISAGAGFSFFLYFLAFVGQEWMMDHIVTVYLVLLSLLVMLILSRLEEKFKKG"
     gene            complement(11561..12352)
                     /locus_tag="VQ862_001192"
     CDS             complement(11561..12352)
                     /locus_tag="VQ862_001192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3115548.1"
                     /translation="MKIPLLTLARHKFVYVLLTLLFLALVYRDVLMTYFFFDIHAPDL
                     AKFDGQAIKNDLLKSALDFRILQFNLGFYQSFIIPIIIVLLGFQYIELKNKVLRLSIG
                     REVSYQGLKRKLTLQVASIPCLIYLVTVLIIAIITYFFGTFSPLEWNSLFSDGSGLQR
                     LLDGEIKSYLFFTCVLLIGIFINAIYFLQIVDYVGNVTRSAITYLMFLWLGSMLLYSA
                     LPYYMVPMTSLMQASYGDVSLMKLFTPYILYVVPYMVLKKYEDNV"
     gene            complement(12537..12872)
                     /locus_tag="VQ862_001193"
     CDS             complement(12537..12872)
                     /locus_tag="VQ862_001193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000400498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3115549.1"
                     /translation="MEYLFKMIILLPCFYFFSWIEKANRDSKIFPIFYYFYWIYITLY
                     ALFSLAWTVFSVLFFNIVLRNLTDIKLWGIWLLLLLIAFASDWLDYICFKKMLDLRRE
                     LGKSKGGRH"
     gene            complement(13012..13347)
                     /locus_tag="VQ862_001194"
     CDS             complement(13012..13347)
                     /locus_tag="VQ862_001194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000400494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3115550.1"
                     /translation="MEHLFKFLLLAPYFYFDNWIEKANRNSKFFPIFYYFYWFYIPFY
                     SLFSLAWTVVSVLFFNTVLRNVTDIKLWGIWFLFILLAIGMNWLTYSCFKEMFRLRQE
                     LGKSKGGRH"
     gene            complement(13438..14748)
                     /gene="der"
                     /locus_tag="VQ862_001195"
     CDS             complement(13438..14748)
                     /gene="der"
                     /locus_tag="VQ862_001195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018377046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase Der"
                     /protein_id="HET3115551.1"
                     /translation="MALPTIAIVGRPNVGKSTLFNRIAGERISIVEDVEGVTRDRIYA
                     TGEWLNRSFSMIDTGGIDDVDAPFMEQIKHQAEIAMEEADVIVFVVSGKEGITDADEY
                     VARKLYKTHKPVILAVNKVDNPEMRNDIYDFYALGLGEPLPISSVHGIGTGDVLDAIV
                     ENLPNEYEEENPDVIKFSLIGRPNVGKSSLINAILGEDRVIASPVAGTTRDAIDTHFT
                     DTDGQEFTMIDTAGMRKSGKVYENTEKYSVMRAMRAIDRSDVVLMVINAEEGIREYDK
                     RIAGFAHEAGKGMIIVVNKWDTLEKDNHTMKNWEEDIREQFQYLPYAPIIFVSALTKQ
                     RLHKLPEMIKQISESQNTRIPSAVLNDVIMDAIAINPTPTDKGKRLKIFYATQVATKP
                     PTFVIFVNEEELMHFSYLRFLENQIRKAFVFEGTPIHLIARKRK"
     gene            complement(14762..15475)
                     /locus_tag="VQ862_001196"
     CDS             complement(14762..15475)
                     /locus_tag="VQ862_001196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000140867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent oxidoreductase"
                     /protein_id="HET3115552.1"
                     /translation="MTETIKLMKAHTSVRRFKEQEIPQVDLNEILTAAQMASSWKNFQ
                     SYSVIVVRSQEKKDALYELVPQEAIRQSAVFLLFVGDLNRAEKGARLHTDTFQPQGVE
                     GLLISSVDAALAGQNALLAAESLGCGGVIIGLVRYKSEEVAELFNLPDYTYSVFGMAL
                     GVPNQHHDVKPRLPLENVVFEEEYQEQSTETIQAYDRVQADYAGGRATTSWSQRLAEQ
                     FGQAEPSSTRKNLEQKKLL"
     gene            complement(15472..16368)
                     /gene="dnaI"
                     /locus_tag="VQ862_001197"
     CDS             complement(15472..16368)
                     /gene="dnaI"
                     /locus_tag="VQ862_001197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein DnaI"
                     /protein_id="HET3115553.1"
                     /translation="MESVGDVLKRQPSRFYYQDLVQKIMKDPDVAAFIQQESLTPEEL
                     NRSISKFNQYITERDKFLRGDTDYIAKGYKPILVKNHGYADVSYEETPELIAAEKEAA
                     IKNRLKLINLPASLKKASLAQVDLDDLGRLPVFEKLLAFVEQYPAIRKGLYLYGDFGV
                     GKSFMVAALAHDLSEKRGVSSTLLHYPSFVIDVKNAISDGNVKTLVDEIKLSEVLILD
                     DIGAEQSTVWVRDEILQVILQYRMQENLPTFFTSNFNFEDLEKHFAKVKHGNDETWEA
                     RRVMERIRYLAEETRLEGVNRR"
     gene            complement(16369..17538)
                     /locus_tag="VQ862_001198"
     CDS             complement(16369..17538)
                     /locus_tag="VQ862_001198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000802368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation and membrane attachment
                     family protein"
                     /protein_id="HET3115554.1"
                     /translation="MKPIDRFSYLKNNRVSQDTSSLVQCYLPIIGQEALSLYLYTISF
                     WDNGRKEYLFSSILNHLNFGMDRLIKSLKILSAFNLLTLYQKGDVYQLALHAPLSSQD
                     FLEHPVYRRLLEKKIGDSAVEDLKVESADGEEIPVSLNQVFPELAELGSQEDLGLKKK
                     VANDFDLEHFRQLMARDGLRFADEQSDVLNLFAIAEEKKWTWFETYQLAKSTAVSQVI
                     STKRMREKIAQKPVSSDFSLKETTIIKEAKSKTALQFLAEIKQTRKGTITQTERELLQ
                     QMAGLGLLDEVINIILLLTFNKVDSANINEKYAMKVANDYAYQKIHSAEKAVLRIRER
                     GQKAKTQKQNQTAPVKTNVPKWSNPEYKNETSEETRLELERKKQELLARLEKGGD"
     gene            complement(17539..18012)
                     /gene="nrdR"
                     /locus_tag="VQ862_001199"
     CDS             complement(17539..18012)
                     /gene="nrdR"
                     /locus_tag="VQ862_001199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001203675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor NrdR"
                     /protein_id="HET3115555.1"
                     /translation="MRCPKCGATKSSVIDSRQAEEGNTIRRRRECDECQHRFTTYERV
                     EERTLVVVKKDGTREQFSRDKIFNGIIRSAQKRPVSSDEINMVVNRIEQKLRGRNENE
                     IQSEDIGSLVMEELAELDEITYVRFASVYRSFKDVSELESLLQQITQSSKKKKER"
     gene            18152..18517
                     /locus_tag="VQ862_001200"
     CDS             18152..18517
                     /locus_tag="VQ862_001200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HET3115556.1"
                     /translation="MSWTFDNKKPIYLQIMEKIKLQIVSHTLEPNQQLPTVRELASEA
                     GVNPNTIQRALSDLEREGFVYSKRTTGRFVTKDKELIAQSRKQLSEEELEHFVSSMTH
                     FGYEKEELPGVVSDYIKGV"
     gene            18522..19217
                     /locus_tag="VQ862_001201"
     CDS             18522..19217
                     /locus_tag="VQ862_001201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3115557.1"
                     /translation="MSLLVFENVSKSYGATPALENVSLDIPAGKIVGLLGPNGSGKTT
                     LIKLINGLLQPDQGRVLINDMDPSPATKAVVAYLPDTTYLNEQMKVKEALTYFKTFYK
                     DFNLERAHHLLADLGIDENSRLKKLSKGNKEKVQLILVMSRDARLYVLDEPIGGVDPA
                     ARAYILNTIINNYSPTSTVLISTHLISDIEPILDEIVFLKDGKVVRQGNVDDIRYESG
                     ESIDQLFRQEFKA"
     gene            19234..20001
                     /locus_tag="VQ862_001202"
     CDS             19234..20001
                     /locus_tag="VQ862_001202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000498762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3115558.1"
                     /translation="MFWNLVRYEFKNVNKWYLALYAAVLVLSALIGIQTQGFKNLPYQ
                     ESQATMLLFLATVFGGLMLTLGISTIFLIIKRFKGSVYDRQGYLTLTLPVSEHHIITA
                     KLIGAFIWSLISTAVLALSAVIILALTAPEWIPLSYVITFVETHLPQIFLTGISFLLN
                     TISGILCIYLAISIGQLFNEYRTALAVAVYIGIQIVIGFIELFFNLSSNFYVNSLVGL
                     NDHFYMGAGIAIVEELIFIAIFYLGTYYILRNKVNLL"
     gene            complement(20354..21553)
                     /locus_tag="VQ862_001203"
     CDS             complement(20354..21553)
                     /locus_tag="VQ862_001203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001245382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET3115559.1"
                     /translation="MRNMWVVIKETYLRHVESWSFFFMVISPFLFLGISVGIGHLQGS
                     SMAKNNKVAVVTTVPSVAEGLKNVNGVNFDYKDEASAKEAIKEEKLKGYLTIDQEDSV
                     LKAVYHGETSLENGIKFEVTGTLNELQNQLNRSTASLSQEQEKRLAQTIQFTEKIDEA
                     KENKKFIQTIAAGALGFFLYMILITYAGVTAQEVASEKGTKIMEVVFSSIRASHYFYA
                     RMMALFLVILTHIGIYVVGGLAAVLLFKDLPFLAQSGILDHLGDAISLNTLLFILISL
                     FMYVVLAAFLGSMVSRPEDSGKALSPLMILIMGGFFGVTALGAAGDNLLLKIGSYIPF
                     ISTFFMPFRTINGYAEGAEAWISLAITVIFAVVATGFIGRMYASLVLQTDDLGIWKTF
                     KRALSYK"
     gene            complement(21550..22443)
                     /locus_tag="VQ862_001204"
     CDS             complement(21550..22443)
                     /locus_tag="VQ862_001204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3115560.1"
                     /translation="MLEVRSLEKSFGSKQVLFGIDFQARPGRILGLVGKNGAGKTTIF
                     HSILKFLEYQGEIGLDGQDIRQEIYARIGYLPEERSLMPKLTVLEQVRYLATLKGMDA
                     KEVKEKLPQWMKRLEVKGKLTDKIKSLSKGNQQKIQLIITLIHEPDLIILDEPFSGLD
                     PVNTELLKQVIFQEKERGATIIFSDHVMTNVEELCDDILMIRDGRVVLHGPVQDVRNQ
                     YGKTRLFVSSERSKEELENLPHVKQVSLTKQGSWKLILEDESAGRELFPILTQGQYIA
                     TFDQQAPTIDEIFKLESGVEV"
BASE COUNT         6649 a         5107 c         4190 g         6689 t
ORIGIN      
        1 tttttgaaaa gtattaacac ctacagacaa gcctgacgat agcaagaact accctactcg
       61 ataggtatcg gcttttgctt tctgaaaaaa attattttaa gcaatttgac aaatctagca
      121 acaaaaaatt ttataaatac aatagattga aactagaata gtacaccttt gcttctaaaa
      181 cattattaga aatcgatttg actgtcctga tcgatttgtc ctgtttttat ttcattttac
      241 tatatttcca tgataaaacg catagtatca agttttctta atcccctgat actatgcgta
      301 tttgtaattt ttaagatttt gtgcttagag tcgactcctt attttagata tttaaaagga
      361 atctcactcc cacagagcca gttgtagact tggtcatcga caaatacatt catggcttcg
      421 tgagcatact caggcatgat gcgataggtt ttatcgcagg tcagacgatt ataaatcgca
      481 aactgggtaa tgggatagca aacatcgtcg tccaagcccg taatcatctt aacctcacct
      541 tggatacgat gggcaagatt tttgacatcg atataggcaa gggtcgccat gatttcctcc
      601 tctgtttcat ggaaggggtc gtgaaacttg aaataacgga aaagttcgtc gtaagcctcg
      661 ctagtattac caatctcaat cacccgtctg aagtctgaca agaagggata aatggcaact
      721 gttttctgaa ttcgaggatt gagcgctgct gcaactagag ctagagcccc tccttgtgag
      781 gcaccatagc tagaaagacg cttctcatca acctgagaca gactagcaac aatttcgacc
      841 aactggtaaa tatccagata aacatcctta taaaagaggt ggtcccgacc ttccatagca
      901 ccacggataa tatgcccctt cacggtattt cctaaaggag aacgcaagcc gtcttgtgag
      961 taacctgact ggccccgcac atccatggaa acaacaccgt aaccagctac ggtgaagccc
     1021 agcatgtcgg cccagtccca gccacgtccc atataaccat gaaaatggaa gattagtgga
     1081 accttctcct cactctttgg aagaacaatg cgtgcataga cctttccttc cttgcttcct
     1141 tcaaatgtta actcatagca cttgacttga ggaatgtgga aatctctttc ctccaagtgg
     1201 taggatggaa gcgtggaaac atttttcact tccccatccc agaaagcatc aaagtcttcc
     1261 ggaacctcat cccttcctct ataggtctta atttcttcta gcaaagctgg atttttcata
     1321 gcatgctcct tttattttgt aatcgttacc acaactgtag catatctatg taatcaatgc
     1381 aagaaagaag gataaataga aagtgaattt agattcttta cttttaggat gataggctga
     1441 aagtagtttt agaaacgaaa aagagcattt cgctctctct tctgtttata ctagtttttt
     1501 gcttccttct tttggaaagt ggtttggtaa tttactttaa tcgttactgt catatgagag
     1561 tcctcgtttc tttttgatga ctttagtata agagccaaac ctaaaaacta gcttaagttt
     1621 tccttagaga aagcttaatc cagatgttct ttcttttcca gatgaagggc aatcatgcgc
     1681 cactctggat cttcttgcca agcttctata gaactaatgt agctagcaac ctttcttgct
     1741 tcttctaaaa tcggaaaatc ttcgataata tcagccactt ggaactctgg aagtcctgac
     1801 tgtctggttc caaaaatctc accagaacca cgcattttca aatcttcctc cgcaaggaca
     1861 aatccattgg tcgtttctgt catgatacgc atgcggtctt tcccagaatc cgtcttggga
     1921 ttagcaacga gaacagcgta ggactgcttg tccccccgac cgacacgacc tctaagctgg
     1981 tgaagttgac tgagaccgaa gcgatcggca tccatgataa tcatgacagt cgcattggga
     2041 acgttgaccc caacctcaat aaccgtcgtc gaaaccagaa tatccgtctt tctctccttg
     2101 aaatcctgca tgatctggtc tttttcgtca ctcttcatcc taccatgtag aagagccacc
     2161 tctgccttgc ctgcaaaatg agtcgtcaac tcctctgata aggcaatggc atttttcaaa
     2221 tctagagctt ctgattcttc aatcaaagga gagatgacat agacttggga acctttttga
     2281 atttccccct ctaaccaagt caagacctga ggtagttgct catgtttgat ccagcgcgtc
     2341 acaataggct tccgacctgc tggcatctgg tcgataatgg aaacatccat atctccaaag
     2401 gctgtgatgg caagcgtccg tggaatggga gtcgccgtca tcatgaggac atctggattg
     2461 tcaccttttt cccgtaaaat acgcctttgc cctacaccaa aacggtgctg ctcatcgata
     2521 ataatcaaac caagacgagc atactccacc ccatcttgta tcagagcgtg agttcctata
     2581 atcaaatcag cctcaccctt ggcaatggtc tccaagactt ctctcttttc tgcagctttc
     2641 aaggaacctg tcaagagagc cagtttcaaa ttgggaaaaa ggttctgtaa actctcaaag
     2701 tgttgctctg cgaggatttc tgttggtacc attagggcag cctgataacc tgctgtcact
     2761 gccgcaaaca tggccaagcc agcgactacc gtttttccac tccccacatc cccttgtagg
     2821 agacgattca tgtggtggtc ggacttcata tcagttaaaa tttcctgcaa actcttttcc
     2881 tgagcttggg tcagggcaaa aggaagactt actttaactg ctgtcacttt ttcctgagac
     2941 caattcagaa ccagaccact tccctgaact ctattttcag acttgagcat ctgcagctgc
     3001 atttggaaat aaaagagttc ctcaaacttt atacggcgaa gagcctgctt gtattctgcc
     3061 aaatcctttg gaaaatgcat agcacggact gcctgacaac gggacatgag tttgtatttg
     3121 tctagtaaag actggggcag attttcttct atcaagaggt ccagtccctg atcaaaagcc
     3181 gtcttgatga ccttgaccag actggcctga ctgattccct gagccagacg atagacaggc
     3241 tggaggtcat cttctacctg agccagaacc ttcatcccag tcagactagc cttagcgcgg
     3301 tcccattttc caaagacagc aagggttgct cccaactcta ttttatcagc cagatagggc
     3361 tggttaaaga aattcaccgc aaaaacgacc tctccctgct tgagactaaa acgcaggcga
     3421 ttgcgcttga aaccataata ctggacacta gcaggagtca ctacctgacc agaaagaact
     3481 gccttctcac cgtcttccag ctccagcacc tgcttggttt tgaagtcttc ataacggaaa
     3541 ggaaagtaga gcaagagatc ttgcaagttt tcaattccta gtttggcgta tttttctgct
     3601 gactttggtc ccacaccagg caagacatgc aagggttgat gtagattcat gctccactcc
     3661 tttcttttct aataatattc tctcggaata cggtcgctga ggaggcaaac cacctcatag
     3721 ttaatggtta cgcggtaggt cgctacctga gttgcagtga tttccttatc cccattggag
     3781 ccaatcaagg ttaccttggt tcctagcgga taaagcttag gcaatcgaat agtgatttgg
     3841 tccatcgaaa ccctgccgac aattgggcaa gcttggccat ctaccaagac agagaaattt
     3901 tgcatgtctc ttgtccatcc atctgcatac ccgattggca cggtcgcgat gacttgctcg
     3961 ctatccgctt gataagttgc tccatagccc atgcaagctc cagctggaac tgtcttgaca
     4021 tgaaccagag cagactccaa ggtcaaggcc ggtatcaaat cataaggcaa atccaagacc
     4081 gctccacttg gattgaggcc atacatggca tctcccatac gaaccgcatt gaaaatagtc
     4141 tctacatgcc aaagagtcgt tgcagaattg ctagcatgaa ccagctctgg aacttccttc
     4201 atactagcta aaatagtttt aaaccgttct aactgggcat taaaatagtc atctgattcc
     4261 tcatcagcag tagcaaagtg ggtaaagatt ccttcaacac aaacaccgtg ttgttggagc
     4321 aaatcttgag cctgctcaac ctcacttgcc tctctaaaac caatccgtcc catccctgaa
     4381 tcaatcttga ggtggactgt caatccagtt aggtccactt ccttatctaa gagtgcttga
     4441 atccactcca gtccagccac tgtcaaggtg aagtcatatt ctttagctag agcaacagct
     4501 tcgatttcag aaactcctaa aatgaggatt ggcttgctga gtccagcttg tctgagttca
     4561 atggcttcat cgatattgga aacgcaaaag ccatcaacat catcttgaat tgccttggca
     4621 acggcaacag ctccatgacc ataagcattg gccttaacca cagccaactt gagcgttcct
     4681 tgagggatat gagcccccat ttgctgaata ttttgtcgaa tagctcccag atgaatcaga
     4741 gccttggttg gtctatgtgg actagctttc atgattttcc tccaaaatga cactggctgt
     4801 cacaaactga tcggtgtggc tgatagacag ccaaatcttt cctgaaaatg gtgcctgact
     4861 aaaataaggc gccccacgtt cattgttcaa gacttccaaa tcctgaaaac cgagcttgct
     4921 aatgcccgtt cccatagcct tggaaaaggc ctccttagcc gaccagcgac cagctaaata
     4981 ttctatttgc ctgcgtcctt tgagactggt gaagcgctcc atttcctgag cggtcagtac
     5041 acgcttagca aatccttcat gtcgtgtaac tgcgctttct atcgaagcca attcttcaat
     5101 gtcaattccg tgtccaacta tcattctcat caaaaggagt tgagattccc caactccatc
     5161 cttttcactt attttgtcaa ggtaacataa atctcttcta ccaaggcctc tgtattttcc
     5221 caacctaggc aagggtcagt aatagagcaa ccaaagatct ctggttggtt ttgacgacca
     5281 tctgctaggt aagattcaat cataaatcct cgaaccgtct ttttaatttt ctcattccaa
     5341 tcacgattct gcaaggtctg gcgaacaatt cgaatctgct ccatatattg cttgcctgag
     5401 ttatcatggt tggtgtcaat gaggataaaa ggattttcaa gtcccatggt ttcatagcgt
     5461 tcaatggctt ggagtagatt ttcatagtag taattcggca tataattgcc atactcgttg
     5521 actgctccac ggaggataac atgggccaaa ggattacctg atgtctcaac ttcctgccca
     5581 tgataaagga aggtttgctt gttttgagca gcatagatgg cgttaaacat aacacccaaa
     5641 tttcctgagg ttggattttt catccctact ggtgcatcaa tcccagaagc cacaaagcgg
     5701 tgctcttggt cttccacaga acgagctcca acggcatggt agctgaccaa gtcatccacc
     5761 aagatcagat ttgacggata aagcatctca tctgccgttg tcaaaccagt ctctgtaatc
     5821 acgcggtagt gcaactggcg cacagcctgc aagccattaa tcaggcttgg agccttagaa
     5881 gtatctggct ggtgaactaa tcctttatag ccgtctccat tggtacgagg cttagcagta
     5941 tacacgcgca tgaccatgaa aatcttatcc gctaccttct tttgcaaggc agataaacgg
     6001 cgagcatatt ccaagaccgc ctcttcatta tcagaagagc aaggaccaat caccaagaga
     6061 atacggtcat cttcccctga aataatatct gccaattccc tgtcacggct ttccttgagt
     6121 ctcaaggctt ccgcagacaa ttgggtttca gccttgatga cttccatatc gatttcttga
     6181 cctttttcaa taaatgccat cttattctcc taacgttttg taaatttctc tgacaagagc
     6241 ttctgtgtta tcccaaccca ggcaagggtc tgtgatagac ttaccaaata cttctggctc
     6301 attttgtcga ccatcttcca gataagactc aatcataaaa ccacgaacga actgcttaat
     6361 tttttcattc caagcacggt taatcaaggt ctggcggaca attcggatct gttcaatata
     6421 ctgcttacca gaattgtcat gattggtatc aatgatgata aaaggatttt ccaagcccat
     6481 tttctcatac tgggcaatgg tatcaattaa attgtcataa tagtagttgg gaatattttt
     6541 tccatactca ttaagagcac cacgaagaat agcgtgtgaa agcgggttcc cagttgtttc
     6601 tacttctttt cctaagaaaa ggaaactttg tttgttttga gcagcataaa tcccattaaa
     6661 catgacattg agatttccag aggttggatt tttaaaacca gtagaaaatc ctgccccact
     6721 tgccacaaag cggtgttgct ggtcttcaac tgaacgggca ccaactgcca tgtaagaaat
     6781 caaatcatct acaagcggaa ggttttcagg ataaagcatt tcatcagcag ttgtcatccc
     6841 tgtttctgtg atgacacgat agtgaagatg gcgaacggct ttgattccat tgataagact
     6901 aggcgcttct gtcgcgttag gctggtgaat caagccctta tagccatctc cgttggtacg
     6961 gggtttggca gtataaacac gcataaccat aaagatacga tctgccactt cttcttgtag
     7021 gactgccaaa cgcttagcgt attcaaggac agcttcttcg ttgtcagatg agcatggccc
     7081 gattaccaag agaattcgct ggtcttctcc acgtataatg gcttctagct cttgatctcg
     7141 ctgtgatttc ctctccaaag cctgaccttc taattttgac aaggcacgaa cttcttctat
     7201 atttatttta gagctttttg ctgtaaatac cataactcat ctccttataa agcaaacgga
     7261 tacccagtaa aaatttactt ttcacaagat atccgcctct aaactatctc attttattgt
     7321 cttttaccgt gacagttttt aaatttctta ccagaaccac atgggcaaag ttcattgcgt
     7381 ccaatctggc tcaaatccaa atcttctggc atacttgctt ggtgagcagc gatattgcga
     7441 gtcgctgttg tactgatatg acgttctgcc tgtggtcttt cttgttcatg aatttgtgct
     7501 ttcatcatca agcgtgtcac atcaaactca atcgaaccaa tcatatcatt aaacatacgg
     7561 aaaccttctg cctgatactc aacaacaggg ttgttctgag catagccacg aagtccaacc
     7621 gcgttacgca attgatcaag ggcatcgata tgatctgtcc acttgttatc caccactcgt
     7681 agaatcaaaa ctttttggaa ttctttaact gcttcttcat cgcgtagttt tgaaacctga
     7741 ctatcgtaaa ccttcaaggc acgttggaaa agctcttcct tgatggcctt atcagacaag
     7801 cctgacaagt cttccatcgt aatagaatct tcaggaagca agttgtactt agcaaagttc
     7861 aaaattgcct ctagtttttc atcttgtttg gcacgcgcat gaccatcaac gacacgttca
     7921 agcgtgcgct taatcataga ctgaatttca ggtgccaagt cacggtctgc agtaatgaca
     7981 tcataacgtt gagtatagat aatctcacgt tgttcacgca tgacatcgtc gtattgaagg
     8041 acttgtttac gggtatcgta gttatttcct tcgacacgtt tctgagctgc ttcaacctga
     8101 cgcgtcaaca tgcgagactc aatcgcctct tcagacatgt tcaagcgttc aaagattccc
     8161 ttcaagcgtt cagaaccaaa acgtttcatc aaatcatctt caagagatag gtagaattgt
     8221 gactcacctg gatctccttg acgacctgaa cgtccacgaa gctggttatc gatacgacga
     8281 ctttcatgac gttctgtacc aataacacaa agtcctccaa gttcacgaac accttcacca
     8341 agcttgatgt cggtaccacg acccgccatg ttggttgcga tggtaacggc accacgttga
     8401 ccagcattca tgatgatttg ggcttctcta tagtggtttt tggcattcaa gacttcgtga
     8461 ggaacaccag ctgcaaccaa tttcttagaa atgtagtcac tagtttcaac cgctactgta
     8521 ccaaccaaga caggttgacc cttttggtaa cgagccttaa cgtcttcgac aaccgcttta
     8581 aacttagatt ctatacttgc ataaagaagg tctgagtggt caatacgttg aacaggacgg
     8641 tttgttggga ttggaataac acgaatgttg tagatttcac ggaattcttc ttcctcagtc
     8701 ttacctgtac ccgtcatacc agacaatttc ttgtacatac ggaaaaggtt ttggtacgtg
     8761 attgaggcag atgtcttggt ttcatcctgg attggcacac cttctttggc ttcaatagct
     8821 tggtgcaatc catcagaata acgacgacct tccatggtac gacctgtaaa ttggtcgaca
     8881 atcaagattt cttgctcttc gctcaccaca tagtcaatat cgagaagcat gatgtagttg
     8941 gcacgaaggg cgttatcgat aaagtgggtc aaagccacgt tttcgatgtc atagaggttt
     9001 tcaagtttga agtagctttc agccctgtca atccctgaat cagacaaacc aatagtctta
     9061 gactgcacat cgatgatgta gtcatctttg ttcaaagatt ttacatagtg gtctgccatg
     9121 tgatacaact gactggtttc aaccgcattg gcacctgata caatcaaagg tgtacgagcc
     9181 tcgtcaatca agatagagtc aacctcatcg accaaggcat agttaagcgg acgttgtacc
     9241 atgttttcag cgcgaacgac catattgtca cgaaggtagt caaatccgat ttctgagtta
     9301 gttgagtaag taatatcaca ctcataggct tcttttttct ccattggaga tttggtagcc
     9361 aagttaatcc ctactgacaa accaagccaa gagtacaatt cacccatctc agtcgcgtca
     9421 cgttctgaca ggtattcatt aaccgtaact acgtgaaccc ctttacctga aagggcattg
     9481 aggtataccg gcatggtcgc agtcaaggtt ttcccttccc ctgtacgcat ctctggcacg
     9541 tcaccatggt gaagaacaat cccccccatg acctgaacct tataagggaa gagacctagg
     9601 acacgtttgg caccttcacg gacaaccgca aatgcttcgt aaagcaatga atccagtgat
     9661 tctccatttt gataacgttc cttaaattca actgtttttg cttttagttg gtcgtcagtc
     9721 aaagcagcca tttggtcttc gtatttgaaa accttgtcag ccatcttttc cagacgacgg
     9781 atttctcctt tatcattttc gataattgtt tttaaaatat tagccatgtt tttccttact
     9841 ttaaattccg aatattttag aatgttcctt taattttagc acaattactg attattttca
     9901 aggaagaatc cccattttga aaaggaaaaa gaggttagtt tccaagctaa cctctctgac
     9961 ttttatgata ctttaattgc caagaatcgg caaaatagca aataggataa ataagttaat
    10021 ccaaagagaa agacagcaga tcaatccaaa aacaaagaga ctgactttct tggacagcaa
    10081 ggccatcaaa atggacagaa tgccaaaaac tagcaagact ttctgtatgc tgaagaggtc
    10141 aatcttcccc ccccccagaa tcggactgcc ccaaggaaga aagaagaaag caatccagat
    10201 caacagaact aaaccaatat agaccttaga atagcgtgta ataaatgatt ttagatgtgc
    10261 cataagccat ctcctaggat tgtatatcct ttacatttgt atatgtccat tttcgacaac
    10321 taatacatct gtacaaaggt ctgaaatatc ttccgatatg tgcgacgtca ggataaccag
    10381 accattttct tttttcaggt aagataaaat gacctgtttg gttaacctca cacttttctc
    10441 atccaaagca ttcataggtt catcgagaaa gagtatagaa ggagaggaaa taaaggcttg
    10501 aatcaaggcc attttttgct ttgttcccaa ggataaatgc cggtattcaa cgtcttcaaa
    10561 ttcctgtaaa tcatagtatt gaatccaata ggcaattctt ttttccgtaa ctttagatga
    10621 aaaatacctt aacagttcca aattttctct cagggataaa tgagataaaa actcgacttt
    10681 ttcaattaaa attcctgcat cctgaatata atgatttttt atcccgtaaa ctttaccatc
    10741 ttgaagaact tttcctttgt caagcttaat ataaccagca agtatcttta aaagaaccgt
    10801 cttgccagat ccattatcac ctttaagtcc ataaattttt cctgattgaa acaccaaatt
    10861 caactgattt aaaataggtc ttttcccata aattttctgt ccatttataa tttcaagtct
    10921 catcgtttat cctttcttaa atttctcttc caagcgacta agaatcaaca taactaataa
    10981 gcttaagagt actaaataca ctgttacaat atgatccatc atccattctt gtcccacaaa
    11041 tgccaaaaaa tagagaaaaa aagaaaaacc agcgcccgca ctaatcagtg ctatcagata
    11101 agacagtagt aagtacaaca tcattaactg agcaagtaaa aagaaaagtg cgactgtttt
    11161 gaaatgaatt cctagcggaa gtaaaccaag aaaccagaca aacaaatctt gagtaaaaaa
    11221 tttagaaatg acaaccaatc gtttccttgt ataatcgaaa aaggagcttg attgatagcg
    11281 aatcaagtga tggtaatggt ctgccaaatc actttcaagt aaaatgacag agagccatcc
    11341 taccatgaaa agcgaaaggt ttaacaagag tttggggatt tctaaattcg cttcagaata
    11401 gtcattatag gaaaaaattg aaatcaattc tctcttgaaa aagataacag catcctgctt
    11461 ttgaaccgct gttgacaata gatagtttat caaaatcatc atcagaacta tacgaagtag
    11521 taaaacgatc tttctcttta gccaaatatt gttaaaattc ttaaacatta tcttcatatt
    11581 ttttaagtac catataaggg acaacataaa ggatataagg agtaaagagt ttcatcaaac
    11641 ttacatcccc atagctagct tgcatcaaac tcgtcatagg aaccatatag taaggcaagg
    11701 cactatagag cagcatagaa ccaagccaaa gaaacatcaa ataggtgatt gccgaacgag
    11761 tcacattccc cacataatca actatttgta aaaaatagat tgcattgatg aaaataccga
    11821 ttagtaggac acaagtaaag aacaaatagc tttttatctc tccatctagg agtctttgta
    11881 aaccactccc atcagaaaat agagaattcc attcaagagg agaaaaagtc ccaaagaaat
    11941 aggttataat tgcaattatc agcacagtca ctaaatatat caaacaaggg atacttgcaa
    12001 cttgcaaagt caactttctt tttaaccctt gatagctcac ttctcttcca atactcaatc
    12061 gtaaaacttt atttttcagc tcaatatatt gaaaacctag caaaacaatg atgattggaa
    12121 taataaatga ttgataaaaa cctagattga actggagaat acgaaaatct aatgctgatt
    12181 ttaataagtc atttttaatt gcttgtccat cgaatttagc tagatcgggc gcatgaatat
    12241 caaaaaagaa ataagtcatc aaaacatcac gataaaccaa agcaagaaaa agcaaagtaa
    12301 gcaagacata aacaaattta tgccttgcca aagttaagag aggaatcttc ataagccacc
    12361 tcctacaaat agaaagtaat ataatactca atgaaaatca aagagcaaac taggaaacta
    12421 gccgcaagtt gctcaaagca ctgctttgag gttgtagata agactgacga agtcagttac
    12481 atatataatc caaggcgacg ttgacgtggt ttgaagagat tttcgaagag tataaatcaa
    12541 tgccttccgc ctttagactt ccctagttcc cgtctcaagt caagcatttt tttgaaacag
    12601 atatagtcta accagtcact agcaaaagcg ataagtagta ataatagcca aataccccat
    12661 aacttgatat ctgtcaaatt tctcaagacg atattgaaaa acagaactga aaaaactgtc
    12721 caagcaaggc taaaaagagc atagagggtg atgtaaatcc agtaaaaata gtaaaaaatt
    12781 gggaaaatct tactatctct gtttgccttt tcaatccagc tgaaaaagta aaaacagggc
    12841 aataagatta tcattttaaa caagtattcc atcacaaacc tcctctttta aattgttttc
    12901 tttagtttcg ttctattaaa tgttattacc aatataaacc ttggaatagc gtgtaataaa
    12961 tgattttaga ggtaccataa gccacctcct acaaatagaa accgatataa atcaatgcct
    13021 tccaccctta gacttcccta gttcctgtct caagcgaaac atttctttga aacaggaata
    13081 agttaaccaa ttcataccaa tagctagcag aataaaaaga aaccaaatgc cccataactt
    13141 gatatctgtc acatttctca agacggtatt gaaaaacaga actgaaacaa ctgtccaagc
    13201 aaggctaaaa agagaataga aggggatgta aaaccagtaa aaataataaa aaattggaaa
    13261 aaacttacta tttctgttgg ccttctcaat ccagttatca aaataaaagt acggtgctaa
    13321 aagtaagaat ttaaacaaat gttccatcac cgacatcacc ctccttcttt tgatagcgtt
    13381 ttctattatt ttattatatc aaaaaaatcc ggaactgtca ttccagattc tactttttta
    13441 tttgcgtttt cttgcgatga gatgaatcgg tgttccctca aaaacaaagg ccttgcggat
    13501 ttgattttcc aagaaacgca ggtaagaaaa gtgcatgagt tcttcttcat tgacaaagat
    13561 gacaaaggtt ggtggtttgg ttgccacttg ggtcgcatag aaaatcttga gacgttttcc
    13621 tttgtctgtc ggtgttgggt tgatggcaat ggcatccatg atgacatcgt tcaagacagc
    13681 tgatggaata cgtgtatttt gactttcgct gatttgctta atcatctcag gaagtttgtg
    13741 gagacgttgc ttagtcaaag ctgatacaaa aataatcggt gcataaggca ggtattggaa
    13801 ctgctcacgg atatcttctt cccagttttt catggtatgg ttgtcttttt caagcgtatc
    13861 ccacttgttg actacgataa tcattccttt accagcttca tgggcaaatc ctgcgatacg
    13921 cttgtcgtac tcacgaatgc cttcttccgc attgatgacc atcaagacca catctgaacg
    13981 gtcaatagca cgcatggcac gcataacaga gtatttctca gtattttcat aaaccttacc
    14041 agacttacgc ataccagccg tatcaatcat ggtaaactct tgaccatctg tatctgtaaa
    14101 gtgggtatca atagcgtcac gagttgttcc agcaacagga ctggcaatga cacggtcttc
    14161 tcccaagata gcattaatca agcttgattt tccaacgtta ggacgaccaa tcaagctaaa
    14221 cttaatgaca tctggatttt cttcttcata ttcatttgga aggttttcca caatcgcatc
    14281 tagtacatcc cctgtaccga taccatggac agatgagata ggcagtggtt cacccaaacc
    14341 gagagcatag aaatcataga tatcatttct catctcaggg ttatccacct tgttgactgc
    14401 gaggataact ggtttgtggg tcttataaag cttgcgggct acgtattcgt ctgcatcggt
    14461 aattccttcc ttaccggaca cgacaaagac gataacatct gcttcttcca tggcaatttc
    14521 tgcctggtgc ttgatttgtt ccatgaaagg agcatcgaca tcatcaattc ctcctgtatc
    14581 aatcatgcta aaagaacgat tgagccactc acccgttgca taaatacggt cacgtgtcac
    14641 tccttcgaca tcttctacaa tggagattcg ctcaccagcg atccgattaa atagggttga
    14701 tttcccaaca ttgggacgtc ctacaatggc aatagttggt agggccataa tttctcactt
    14761 tctacaataa tttcttctgt tcaagatttt ttctagttga gcttggttca gcttgaccaa
    14821 actgttctgc taggcgctga ctccagcttg tggtcgcacg ccccccagca tagtcagcct
    14881 gcacacggtc ataagcttgg attgtctcag ttgactgttc ttggtattct tcctcaaaga
    14941 caacattctc tagtggcagt ctcggtttca catcatgatg ttgatttggc acacccagtg
    15001 ccatcccaaa gacagaatag gtgtagtcag gtaggttaaa gagctctgcc acttcttcag
    15061 acttgtatcg aaccaaaccg ataatcacac caccacagcc caagctttca gctgccaaca
    15121 aggcgttttg tccagcaaga gctgcatcga ccgaactaat caagagacct tccacacctt
    15181 ggggttggaa ggtgtcggta tgaagtcggg ctcccttttc tgctcggttc aaatctccga
    15241 caaagagaag gaaaacagca gactggcgaa tggcttcttg aggtaccaat tcatacaagg
    15301 catctttctt ctcttgactt cgtaccacaa tcacagagta ggattggaaa ttcttccaag
    15361 atgatgccat ctgggctgct gtcaaaatct catttaagtc tacttgggga atttcttgct
    15421 ctttaaacct gcgcactgaa gtatgagcct tcatcaattt aatggtttct gtcatcgacg
    15481 gtttactcct tctaaacgag tctcctcagc caaataacgg atgcgttcca tgacccgtct
    15541 ggcttcccag gtttcgtcat ttccatgttt cactttcgca aaatgcttct ccaaatcttc
    15601 aaagttgaag ttggatgtga aaaaggtcgg taaattttcc tgcatccgat attggagaat
    15661 gacctgcagg atttcgtcac gtacccaaac ggttgattgc tcggcgccaa tatcatctaa
    15721 aatcaggacc tcagacagct taatctcatc caccaaggtc ttaacattgc catcactgat
    15781 agcatttttg acatcaatga caaagctagg atagtggagg agagttgatg aaacaccacg
    15841 tttttctgat aaatcatgag ctaaggccgc caccatgaaa cttttaccca caccaaagtc
    15901 tccatataag taaagacctt ttcgaatagc tggatattgc tccacgaagg ctagtagctt
    15961 ttcaaaaact ggtaagcgcc ccaaatcatc caagtcaact tgagccaaac tagctttctt
    16021 gagactggct ggtagattga ttaacttgag acggttctta atagccgctt ctttttcagc
    16081 cgcgattagc tcaggagttt cttcatatga aacatctgca tagccatgat tcttaaccaa
    16141 aatcggcttg tagcctttgg caatataatc cgtatcccca cggagaaact tgtcacgctc
    16201 ggtgatgtac tgattaaact tggagatact gcgatttaat tcctctggag tcaaggattc
    16261 ttgctggata aaagccgcaa catcagggtc cttcatgatt ttctggacca aatcttgata
    16321 ataaaaacgg ctgggttgac gtttgagtac gtctccgaca ctttccatct aatctcctcc
    16381 tttttctaat cgagctaata gttcttgctt cttacgttct agttccagac gagtttcctc
    16441 gctggtttca ttcttatatt caggattact ccatttagga acattggttt ttactggggc
    16501 agtctgattc tgtttttgtg tttttgcttt ctgtcctcgc tcacggatgc gcaagactgc
    16561 cttttctgcc gaatgaatct tttgataggc atagtcattg gctaccttca tggcatattt
    16621 ctcattgata tttgccgaat cgaccttatt aaaggtcaat aaaagaatga tattgatgac
    16681 ttcgtccagc aagcccaagc cagccatctg ttgcaagagt tctctttctg tttgggtaat
    16741 ggttcccttg cgtgtttgct tgatttctgc caagaactgc agggcagttt tacttttggc
    16801 ttctttgata atggttgttt ccttaagact aaagtcagag gaaactggtt tttgagcaat
    16861 tttttcacgc atgcgtttgg ttgaaataac ctgagaaaca gctgttgact tggccaattg
    16921 ataggtttca aaccaagtcc atttcttctc ctcggcaata gcaaagaggt ttaagacatc
    16981 ggactgctca tccgcaaaac gaagtccatc tcgagccatc agctggcgaa aatgttccaa
    17041 gtcaaaatca ttggccactt tcttcttgag accaaggtct tcttgactgc ctagttctgc
    17101 caattctgga aagacttgat tgagtgagac aggtatttct tcaccatcag cactttcaac
    17161 tttcaaatcc tccacagcag agtcgccaat ctttttctct aagagtctgc gataaacagg
    17221 atgctccaag aagtcttgac tagatagagg agcatggagg gctagctgat aaacatcccc
    17281 cttttgatag agggtcaaga gattaaaagc agataagatt ttcaatgatt ttatcagtct
    17341 atccatccca aagttgagat gattgaggat acttgaaaaa agatattcct ttctaccatt
    17401 atcccaaaaa ctgattgtat aaagataaag gctcagtgcc tcctgaccga taatcgggag
    17461 gtagcactgt accagagatg aggtatcttg cgacacccga ttattcttta gataagaaaa
    17521 acggtcaatt ggcttcattt atctttcctt tttcttttta gaggactggg tgatttgttg
    17581 gagcaagctc tctaactcac tgacatcctt aaaactacga tagacactag caaaacgtac
    17641 ataggtaatc tcgtccaatt cagccaactc ctccatgacg agtgaaccaa tgtcctcact
    17701 ttgaatttca ttttcatttc gaccacggag tttctgttcg atacgattga ctaccatgtt
    17761 gatttcatca cttgacacag gacgtttctg ggctgagcgg ataatcccat taaagatttt
    17821 atctctggag aattgttccc gtgtaccatc ttttttaaca accactaagg ttctttcttc
    17881 tactcgttcg taggttgtaa aacggtgttg gcattcgtcg cactcacgtc ttctacgaat
    17941 ggtgttccct tcttctgctt ggcgactatc gataacactt gacttggtag ccccacattt
    18001 tggacaacgc atcctttccc tccttatcgt tttcttttca ttataccatt ttttaagcga
    18061 ttcccaaaac aattcttctt tttgcttgac aagttttttg ttttattgta ttatttaatt
    18121 aagaaaaaag gataagagaa aggagactaa gatgtcctgg acatttgaca acaaaaaacc
    18181 catctattta cagattatgg agaaaatcaa gcttcagatt gtttcccata cactggaacc
    18241 caatcaacaa cttccaaccg tgagggagct agctagcgag gctggtgtca atcccaatac
    18301 catccaaaga gccttatcag accttgaacg agaaggattt gtctacagca agcgaacaac
    18361 tggacgattt gtgactaagg ataaggagct aatcgcccag tcacgcaaac aattatcaga
    18421 agaagaattg gaacacttcg tttcctccat gacccatttt ggctatgaaa aagaagaact
    18481 accaggcgta gtcagtgatt atattaaagg agtttaagcc tatgtcatta ctagtatttg
    18541 aaaatgtatc caaatcatat ggagcaacac cagcccttga aaatgtttct cttgacattc
    18601 cagctggaaa aattgtcggc cttcttgggc caaacggctc aggaaaaaca accctgatta
    18661 aactaattaa tggcctctta caaccagatc aaggacgtgt cctcatcaac gacatggacc
    18721 caagcccagc aaccaaggcc gttgtagctt atttgcctga tacgacctat ctcaatgagc
    18781 aaatgaaggt caaagaagcc ctaacctact tcaagacctt ctataaagat ttcaatcttg
    18841 aacgcgccca tcatctactt gcagacctgg gcattgatga aaatagtcgt ctcaagaaac
    18901 tatcaaaagg aaacaaagaa aaggttcaac tgattttggt tatgagccgt gatgctcgtc
    18961 tctatgtttt ggacgaaccc attggtgggg tggatccagc agcccgtgct tatatcctca
    19021 ataccattat caacaactac tcaccaactt ctaccgtttt gatttctacc cacttgattt
    19081 ctgatatcga gccaatcttg gatgaaattg tcttcctaaa agacggaaaa gtcgtccgtc
    19141 aaggaaatgt agatgatatt cgctacgagt caggtgaatc cattgaccaa ctcttccgtc
    19201 aggaatttaa ggcctaagca aaggagatta tttatgtttt ggaatttagt tcgctacgaa
    19261 tttaaaaatg ttaacaagtg gtatttagcc ctctacgcag ccgtgctagt cctttctgcc
    19321 ctcatcggaa tacagacaca aggctttaaa aatctacctt accaagaaag tcaggctact
    19381 atgctacttt ttctagctac agtctttggt ggcttgatgc ttacacttgg gatttcaacc
    19441 attttcttga ttattaaacg cttcaaaggt agtgtctacg accgacaagg ctatctgact
    19501 ttgaccttgc cagtttctga acaccatatc atcacagcca aactaatcgg tgcctttatc
    19561 tggtcattga ttagcaccgc tgtattggct ctaagtgctg ttattattct ggctttaaca
    19621 gctccagaat ggattcctct ttcttatgtg attacatttg tagaaacaca tctccctcag
    19681 atctttctta caggtatatc cttcctacta aatactattt caggaatcct ctgcatctac
    19741 ctggctattt ccattggaca gcttttcaat gaataccgta cagcactcgc tgttgcagtc
    19801 tacattggta tccaaatcgt cattggattt attgaacttt tcttcaatct tagttctaat
    19861 ttctatgtca attcactggt aggactcaat gaccatttct atatgggagc aggtatagcc
    19921 attgttgaag aactcatatt catagctatc ttttatctcg gaacctacta catcttgaga
    19981 aataaggtta atttgcttta aataattttt acctagatat gtaacatact catagaacaa
    20041 aagagaccag gcaaaaagtc tttacaatta gaaaacgcat agtatcaagt gttaaaaatc
    20101 cttgatatta tgcgtttttt gtgagctgac ttatttcctt tcactatatc gcaaaatgaa
    20161 ataagaacgg aacgatggga ttttggaatt caaatcaatt tataagaatg ttttagaagt
    20221 aatattatcc tattccagat tcagttcact atacaattga gttttcaagc aacctgttta
    20281 cataatgtgt acataattag gttcgtgatt ccaccctttt cacctttaaa aacctcgctt
    20341 tcgcaaggct cttctattta taagataagg cacgtttaaa ggttttccaa atccctaaat
    20401 catccgtttg aagaacgaga ctagcataca tgcgtccgat aaatcctgtt gctaccaccg
    20461 caaaaatcac tgtaatagca agtgaaatcc atgcttccgc tccctccgca tagccattaa
    20521 tcgttcgaaa cggcataaag aaggtcgaaa taaagggaat ataagaacca atcttcaaga
    20581 ggagattgtc accagctgca cctagagctg tcactccaaa aaaaccaccc ataatcaaaa
    20641 tcatcaaagg cgacaaggct ttccctgagt cttcaggacg agaaaccata gatcctagga
    20701 aggctgccaa gactacgtac atgaaaagac tgatcaaaat aaagagcaag gtattcagtg
    20761 agatagcatc tcccaagtga tccaaaatac cagactgagc caagaatggc aaatctttaa
    20821 agagcaaaac ggcagccaga ccacctacaa catagatccc aatatgcgtt aaaatcacta
    20881 gaaacagagc catcatccgc gcatagaaat agtgacttgc ccttatgcta gaaaagacga
    20941 cttccataat tttggtgcct ttttcactgg caacttcctg agctgttaca cccgcatagg
    21001 taatcagaat catataaaga aagaatccta aggcacctgc tgcaattgtt tgaataaact
    21061 ttttattttc cttggcttca tcaatctttt ctgtgaattg aattgtctgc gctaagcgtt
    21121 tttcctgctc ttgagacaag gaagcagttg aacgattaag ctgattttgc agttcattga
    21181 gtgtacctgt aacctcaaat ttaattccat tttcaagcga tgtttcgcca tgataaactg
    21241 cctttagaac actatcttct tgatcaatgg tcaaataacc ttttaatttt tcttctttaa
    21301 ttgcttcttt ggcacttgct tcgtctttat agtcgaagtt aacaccattt acattcttca
    21361 gtccttctgc tacagatggc actgttgtca ctactgccac tttattattt ttagccatag
    21421 aagaaccttg gagatgccca attcctacag agattcctaa aaagaggaac ggcgaaatca
    21481 ccataaagaa gaaactccat gactcgacat gtcgaagata ggtttccttg attacaaccc
    21541 acatatttct catacttcca ctcctgattc tagtttaaag atttcatcga tagttggcgc
    21601 ttgttggtca aatgttgcga tatattgacc ttgagtcaag attgggaaga gttcccttcc
    21661 agcgctctca tcctccaaaa tcaatttcca actgccttgt ttggtcaagc tcacctgttt
    21721 gacatgagga agattttcca attcttcctt gcttcgttca cttgaaacaa agagacgcgt
    21781 tttcccgtat tgattgcgga catcctgaac tggtccgtgc aagaccacac ggccatctcg
    21841 aatcatcaga atatcgtcac aaagttcctc aacattggtc atgacatggt cagaaaagat
    21901 aatggttgct ccgcgctctt tttcctgaaa aatgacttgt ttgagcaatt ctgtattaac
    21961 tgggtccaat ccactaaaag gctcatccaa gataatcagg tctggttcat gaatcagagt
    22021 aataatgagc tgaatcttct gctgatttcc ttttgacaga ctcttgattt tatctgtcag
    22081 ctttcctttt acttccaacc tcttcatcca ttgagggagt ttttctttga cttctttggc
    22141 atccatgcct tttagagtcg ccaagtagcg aacttgttca agaactgtca atttaggcat
    22201 gagactgcgt tcttcaggca gataaccaat ccgagcatag atctcctgac gaatatcctg
    22261 accatccaga ccgatttctc cctgatattc taggaatttt aaaatactat ggaaaatcgt
    22321 tgtttttcca gcaccatttt ttccgactag tcccaaaata cgacctggtc gcgcttgaaa
    22381 gtcaatacca aacaaaactt gcttggatcc aaaacttttc tctagacttc ttacttctag
    22441 catctttcac ctccgaaatt tcttgcactc attatactcc tttttgatag cctttacaat
    22501 gttttttgtc catttttaga agactattgc tgtgtaaaat atggcctgga gcacttttat
    22561 actcaatgaa aatcaaagag caaactagga agccagccgt agactgctca aagtacagct
    22621 ttgaggttgc agata
//
LOCUS       DAVBOD010000028        22277 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 640-05
            SAMEA1012484-rid20186543.denovo.028, whole genome shotgun sequence.
ACCESSION   DAVBOD010000028 DAVBOD010000000
VERSION     DAVBOD010000028.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012484
            Sequence Read Archive: ERR059358
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 22277)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22277)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979948.1
            Genome Coverage       :: 595x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:03:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,266
            CDSs (total)                      :: 2,219
            Genes (coding)                    :: 2,091
            CDSs (with protein)               :: 2,091
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 71 of 128
            Pseudo Genes (incomplete)         :: 50 of 128
            Pseudo Genes (internal stop)      :: 33 of 128
            Pseudo Genes (multiple problems)  :: 22 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22277
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012484-rid20186543.denovo.028"
                     /strain="NIG 640-05"
                     /db_xref="taxon:1313"
     gene            complement(249..536)
                     /locus_tag="VQ862_001205"
     CDS             complement(249..536)
                     /locus_tag="VQ862_001205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3115561.1"
                     /translation="MKLSNLLLFAGAAAGSYLVTKNRQTITDEVLNTTDRVQAIKDDV
                     DIIQNSLQIINQQKELIKEYQEDLTYKFKVLEKDIQTRLAVIKEMQGTEDK"
     gene            complement(546..956)
                     /locus_tag="VQ862_001206"
     CDS             complement(546..956)
                     /locus_tag="VQ862_001206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HET3115562.1"
                     /translation="MSDCIFCKIIAGEIPASKVYEDEQVLAFLDISQVTLGHTLVVPK
                     EHYRNLLEMDATSASQLFAQVPKVAQKVMKVTKAAGMNIISNCEEVAGQTVFHTHVHL
                     VPRYSADDDLKIDFIAHEPDFDKLAQVAETIKNA"
     gene            1024..1755
                     /locus_tag="VQ862_001207"
     CDS             1024..1755
                     /locus_tag="VQ862_001207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000889926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3115563.1"
                     /translation="MLEIKNLTGGYVHVPVLKDVSFTVESGQLVGLIGLNGAGKSTTI
                     NEIIGLLAPYSGSININGLTLQGDATSYRKQIGYIPETPSLYEELTLREHIETVAMAY
                     GIEQKVAFERVEPLLKMFRLEQKLDWFPVHFSKGMKQKVMIICAFVVDPSLFIVDEPF
                     LGLDPLAISDLIQLLEVEKQKGKSILMSTHVLDSAEKMCDAFVILHKGEVRAKGNLLQ
                     LREAFDMPEASLNDIYLALTKEEDL"
     gene            1752..2801
                     /locus_tag="VQ862_001208"
     CDS             1752..2801
                     /locus_tag="VQ862_001208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET3115564.1"
                     /translation="MKDLFLKRKQAFRKECLGYLRYVLNDHFVLFLLVLLGFLAYQYS
                     QLLQHFPENHWPILLFVGITSVLLLLWGGIATYMEAPDKLFLLVGEEEIKLHLKRQTG
                     ISLVFWLFVQTLFLLLFAPLFLAMGYGLPVFLLYVLLLGVGKYFHFRQKASKFFTETG
                     LDWDYLISQESKRKQVLLRFFALFTQVKGISNSVKRRAYLDFILKAVQKVPGKIWQNL
                     YLRSYLRNGDLFALSLRLLLLSVLAQVFIEQAWIATAVVVLFNYLLLFQLLALYHAFD
                     YQYLTQLFPLDKGQKEKGLQEVVRGLTSFVLLVEVVVGLITFQEKLALLALLGAGLVL
                     LVLYLPYQVKRQMQD"
     gene            complement(2969..3298)
                     /locus_tag="VQ862_001209"
     CDS             complement(2969..3298)
                     /locus_tag="VQ862_001209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase BlpT"
                     /protein_id="HET3115565.1"
                     /translation="MTDTDPIKRAQTLITDLNKAYQACKQATADDVRFQEQLNSILGF
                     LAKAETVDNRFLIELEKFYQTSSLLMGLSALDPDAPTRAAWRAYDRFHFDQVKTKLIL
                     NENQRAN"
     gene            3575..3913
                     /locus_tag="VQ862_001210"
     CDS             3575..3913
                     /locus_tag="VQ862_001210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000682119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET3115566.1"
                     /translation="MKHMIIQTQKTVYKVNVDDVYYIQTHPTKAHTVKIVTEEASFNM
                     VQNLSNLENQYGETLMRCHRNCLVNLDKVKSIDFQERILFLGEEGQYAVKYARRRYRE
                     IRQKWLKEGE"
     gene            3918..4655
                     /locus_tag="VQ862_001211"
     CDS             3918..4655
                     /locus_tag="VQ862_001211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001219153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET3115567.1"
                     /translation="MRIFVLEDDFSQQTRIETTIEKLLKEHHITLSSFEVFGKPDQLL
                     AEVHEKGAHQLFFLDIEIRNEEMKGLEVARKIRDRDPYALIVFVTTHSEFMPLSFRYQ
                     VSALDYIDKALSAEEFESRIETALLYANGQDSKSLAEDCFYFKSKFAQFQYPFKEVYY
                     LETSTRPHRVILYTKTDRLEFTASLEEVLKQEPRLLQCHRSFLINPANVVHLDKKEKL
                     LFFPNGGSCLIARYKVREVSEAINNLH"
     gene            4669..6009
                     /locus_tag="VQ862_001212"
     CDS             4669..6009
                     /locus_tag="VQ862_001212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001099894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HET3115568.1"
                     /translation="MNVAWILLYTLVTHGLKIVIFFKVDGISLTFERIFKAFLFKILL
                     AVVFGMLGYMVGNVYLSYFMEPLYGIGLSFLLLRELPKKLLLFYGLFPMILVNLFYRG
                     VSYFVLPFLGQGQVYDDYSFIWLCIIIFNFFISLAFLKWLDYDFTSLRKGILDKDFQK
                     SLTQINWIMGAYYLVIQNLSYFEYEQGIQSTTVRHLILVFYLLFFMGIIKKLDTYLKD
                     KLHERLNQEQDLRYREMERYSRHIEELYKEVRSFRHDYTNLLTSLRLGIEEEDMEQIK
                     EIYDSVLKDSSEKLQDNKYDLGRLVNVRDRALKSLLAGKFIKARDKNIVFNVEVPEEI
                     QVEGVSLLDFLTVVSILCDNAIEASVEACQPHVSIAFFKNGAQETFIIENSIKEEGID
                     ISEIFSFGASSKGEERGVGLYTVMKIVESHPNTSLNTTCQDHVFRQVLTVIHIE"
     gene            complement(6053..6208)
                     /gene="blpC"
                     /locus_tag="VQ862_001213"
     CDS             complement(6053..6208)
                     /gene="blpC"
                     /locus_tag="VQ862_001213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quorum-sensing system pheromone BlpC"
                     /protein_id="HET3115569.1"
                     /translation="MDKKQNLTSFQELTTTELNQIIGGGWWEDFLYRFNIIEQKNTKG
                     FYQPIQL"
     gene            complement(6265..7626)
                     /locus_tag="VQ862_001214"
     CDS             complement(6265..7626)
                     /locus_tag="VQ862_001214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001069090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin secretion accessory protein"
                     /protein_id="HET3115570.1"
                     /translation="MNPNLFRSVEFYQRRYHNYATVFIIPLSLLFTFILIFSLVATKE
                     ITVTSQGEIAPTSVIASIQSTSDNPILANHLVANQVVEKGDLLIKYSETMEESQKTAL
                     ATQLQRLEKQKEGLGILKQSLEKATDLFSSEDEFGYHNTFMNFTKQSHDIELGISKTN
                     TEVSNQANLTNSSSSAIEQEITKVQQQIGEYQELRDAIINNRARLPTGNPHQSILNRY
                     LIASQGQTQGTAEEPFLSQINQSIASLESSIASIKIQQAGIGSVATYDNSLATKIEVL
                     RTQFLQTASQQQLTVENQLTELKVQLDQATQRLENNTLTAPSKGIVHLNSEFEGKNRI
                     PTGTEIAQIFPVITDTREVLITYYVSSDYLPLLDKGQTVRLKLEKIGNHGTTIIGQLQ
                     SIDQTPTRTEQGNLFKLTALAKLSNEDSKLIQYGLQGRVTSVTTKKTYFDYFKDKILT
                     HSD"
     gene            complement(7637..9790)
                     /gene="blpA"
                     /locus_tag="VQ862_001215"
     CDS             complement(7637..9790)
                     /gene="blpA"
                     /locus_tag="VQ862_001215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_125458604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide cleavage/export ABC transporter BlpA"
                     /protein_id="HET3115571.1"
                     /translation="MTSYKRTFVPQIDARDCGVAALASIAKFYGSDFSLAHLRELAKT
                     NKEGTTALGIVKAADEMGFETRPVQADKTLFDMSDVPYPFIVHVNKEGKLQHYYVVYQ
                     TKKDYLIIGDPDPSVKITKMSKERFFSEWTGVAIFLAPKPSYQPHKDKKNGLLSFLPL
                     IFKQKSLIAYIVLSSLLVTIINIGGSYYLQGILDEYIPNQMKSTLGIISVGLVITYIL
                     QQVMSFSRDYLLTVLSQRLSIDVILSYIRHIFELPMSFFATRRTGEIISRFTDANSII
                     DALASTILSLFLDVSILILVGGVLLAQNPNLFLLSLLSIPIYMFIIFSFMKPFEKMNH
                     DVMQSNSMVSSAIIEDINGIETIKSLTSEENRYQNIDSEFVDYLEKSFKLSKYSILQT
                     SLKQGTKLVLNILILWFGAQLVMSSKISIGQLITFNTLFSYFTTPMENIINLQTKLQS
                     AKVANNRLNEVYLVESEFQVQENPVHSHFLMGDIEFDDLSYKYGFGRDTLTDINLTIK
                     QGDKVSLVGVSGSGKTTLAKMIVNFFEPYKGHISINYQDIKNIDKKVLRRHINYLPQQ
                     AYIFNGSILENLTLGGNHMISQEDILRACELAEIRQDIERMPMGYQTQLSDGAGLSGG
                     QKQRIALARALLTKAPVLILDEATSGLDVLTEKKVIDNLISLTDKTILFVAHRLSIAE
                     RTNRVIVLDQGKIIEVGSHQELMQAQGFYHHLFNK"
     gene            10072..10326
                     /gene="blpM"
                     /locus_tag="VQ862_001216"
     CDS             10072..10326
                     /gene="blpM"
                     /locus_tag="VQ862_001216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000379879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-peptide bacteriocin subunit BlpM"
                     /protein_id="HET3115572.1"
                     /translation="MNTKMMEQFHEMDIAMLSSIEGGKNNWQTNVFEGGSAAFGGWGL
                     GTAICAASGVGAPFMGACGYIGAKFGVALWAGVTGATGGF"
     gene            10342..10545
                     /gene="blpN"
                     /locus_tag="VQ862_001217"
     CDS             10342..10545
                     /gene="blpN"
                     /locus_tag="VQ862_001217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001099492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-peptide bacteriocin subunit BlpN"
                     /protein_id="HET3115573.1"
                     /translation="MNTYCNINETMLSEVYGGNSGGAAVVAALGCAAGGVKYGKILGP
                     WGAAIGGIGGAVVCGYLAYTATS"
     gene            10789..10938
                     /gene="blpO"
                     /locus_tag="VQ862_001218"
     CDS             10789..10938
                     /gene="blpO"
                     /locus_tag="VQ862_001218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpO"
                     /protein_id="HET3115574.1"
                     /translation="MNTKMMSQFSVMDNEMLACVEGGDIDWGRKISCAAGVAYGAIDG
                     CATTV"
     gene            11042..11161
                     /locus_tag="VQ862_001219"
     CDS             11042..11161
                     /locus_tag="VQ862_001219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000346296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin"
                     /protein_id="HET3115575.1"
                     /translation="MDFKSFIIGLVVGIFGPYMDDLIRKIFSKSSKKDTDSTL"
     gene            11629..12000
                     /locus_tag="VQ862_001220"
     CDS             11629..12000
                     /locus_tag="VQ862_001220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3115576.1"
                     /translation="MIKKNHILCEIVPGSVAFACFYLSISISSVFQFLLVVINLASIL
                     VTVYLTREMRIKEFEDDDLVSPRTNQLMFIGLTGFMSIICLYRGITAGESYQQIIAYI
                     GAILCLTIMLLLIWGLKYYKK"
     gene            12629..13012
                     /locus_tag="VQ862_001221"
     CDS             12629..13012
                     /locus_tag="VQ862_001221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="immunity protein"
                     /protein_id="HET3115577.1"
                     /translation="MKYRLFFVIFLSSVLDILLGTFLQISIVSIGWLVLYSGLFEAGV
                     FLLANKGVAVKIKEVDIRNRFKFIFGKTLWFQILLLIFLIIKLYLGLDARLILFYGHI
                     FIVFNALMYLLSSSQVSLKKNKLSS"
     gene            13064..13753
                     /locus_tag="VQ862_001222"
     CDS             13064..13753
                     /locus_tag="VQ862_001222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000760553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET3115578.1"
                     /translation="MKKYQLLFKISAVFSYLFFVFGLSQMTLIIQNYWQFSSQIGNFV
                     WIQNFLSLLFSGVMIWILVKTGHGYLFHIPRKKWLWYSILTVLVVVLQISFNVQTAKH
                     VQSTAEGWAVLIGYSGTNFAELGIYITLFFLTPLMEELIYRGLLQHAFFKHSRFGLDL
                     LLPSILFALPHFSSLPSLLDIFIFATSGIIFASLTRYTKSIYPSYAVHVINNIFATLP
                     FLLTFLHRVLG"
     gene            13795..14028
                     /locus_tag="VQ862_001223"
     CDS             13795..14028
                     /locus_tag="VQ862_001223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3115579.1"
                     /translation="MYKHLFFLDSKTLDRLTPYILVLASDTIAFNVFVLTFVSAVVFN
                     FLNSMLALMAIFIGAGYVVGFWLLILNENQRAN"
     gene            14179..14790
                     /locus_tag="VQ862_001224"
     CDS             14179..14790
                     /locus_tag="VQ862_001224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000394041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET3115580.1"
                     /translation="MEFFDKFHALCFGFLVLIIVITVPYTINHGVFFQNESALILVSL
                     LVTSLSVAYARKFEMISFGMLSKKQLLLFIAIFLLSVLETLVYIHFFAVSSGSGVQHL
                     AEVSRGISLSLILTTSVFGPIQEELIFRGLLQGAVFDNSWLGLVLTSSLFSFMHGPSN
                     VPSFIFYLLGGLLLGFAYKKSQNLWVSTLVHMFYNSWPLLYYL"
     gene            14951..15745
                     /locus_tag="VQ862_001225"
     CDS             14951..15745
                     /locus_tag="VQ862_001225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000363010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphotransferase family protein"
                     /protein_id="HET3115581.1"
                     /translation="MDLGDNELTLTPIPGKSGKAYMGSYPDGKRIFVKMNTSPILPGL
                     AREQIAPQLLWSRRLADGRDMCAQEWLTGKILTPYDMNRKQIVNILTRLHRSRPLMTQ
                     LSRLGYAMETPVDLLQSWQETAPDALRKNHFISEVMADLRQTIPGFREDHATIVHGDV
                     RHSNWIETDSGLIYLVDWDSVRLTDRMFDVAHMLCHYISEHQWKEWLTYYGYKYNQTV
                     LSKLYWYGQLSYLSQISKYYMNQDLENVNREIHGLRHFRDKYGKRR"
     gene            15742..16377
                     /gene="trmB"
                     /locus_tag="VQ862_001226"
     CDS             15742..16377
                     /gene="trmB"
                     /locus_tag="VQ862_001226"
                     /EC_number="2.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001266107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(46)-N7)-methyltransferase TrmB"
                     /protein_id="HET3115582.1"
                     /translation="MRVRNRKGATELLEANPQYVVLNPLEAKAKWRDLFGNDNPIHVE
                     VGSGKGAFVSGMAKQNPDINYIGIDIQKSVLSYALDKVLEVGVPNIKLLWVDGSDLTD
                     YFEDGEIDRLYLNFSDPWPKKRHEKRRLTYKTFLDTFKRILPENGEIHFKTDNRGLFE
                     YSLVSFSQYGMKLNGVWLDLHASDFEGNVMTEYEQKFSNKGQVIYRVEAEF"
     gene            16503..16982
                     /gene="rimP"
                     /locus_tag="VQ862_001227"
     CDS             16503..16982
                     /gene="rimP"
                     /locus_tag="VQ862_001227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000338698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimP"
                     /protein_id="HET3115583.1"
                     /translation="MDAIATIVELVREVVEPVIEAPFELVDIEYGKIGSDMILSIFVD
                     KPEGITLNDTADLTEMISPVLDTIKPDPFPEQYFLEITSPGLERPLKTKDAVAGAVGK
                     YIHVGLYQAIDKQKVFEGTLLAFEEDELTMEYMDKTRKKTVQIPYSLVSKARLAVKL"
     gene            17026..18162
                     /gene="nusA"
                     /locus_tag="VQ862_001228"
     CDS             17026..18162
                     /gene="nusA"
                     /locus_tag="VQ862_001228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusA"
                     /protein_id="HET3115584.1"
                     /translation="MSKEMLEAFRILEEDKGIKKEDIIDAVVESLRSAYRRRYGQSDS
                     VAIDFNEKTGDFTVYTVREVVDEVFDSRLEISLKDALAINSAYELGDKIKFEEAPAEF
                     GRVAAQSAKQTIMEKMRKQTRAITYNTYKEHEQEIMSGTVERFDNRFIYVNLGSIEAQ
                     LSKQDQIPGEVFASHDRIEVYVYKVEDNPRGVNVFVSRSHPEMIKRLMEQEIPEVYDG
                     TVEIMSVAREAGDRTKVAVRSHNPNVDAIGTIVGRGGANIKKITSKFHPARYDAKNDR
                     MVPIEENIDVIEWVADPAEFIYNAIAPAEVDQVIFDENDSKRALVVVPDNKLSLAIGR
                     RGQNVRLAAHLTGYRIDIKSASEFEAMEDAASVELEVENDTVEE"
     gene            18184..18477
                     /locus_tag="VQ862_001229"
     CDS             18184..18477
                     /locus_tag="VQ862_001229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000857559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxR family protein"
                     /protein_id="HET3115585.1"
                     /translation="MKTRKIPLRKSVVSNEVIDKRDLLRIVKNKEGQVFIDPTGKANG
                     RGAYIKLDNAEALEAKKKKVFNRSFSMEVEESFYDELIAYVDHKVKRRELGLE"
     gene            18470..18769
                     /locus_tag="VQ862_001230"
     CDS             18470..18769
                     /locus_tag="VQ862_001230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxQ-related RNA-binding protein"
                     /protein_id="HET3115586.1"
                     /translation="MNKQKISNLLGLAQRAGRIISGEELVVKAIQDGKAKLVFLAHDA
                     GPNLTKKIQDKSHYYQVEIVTVFSTLELSIAVGKSRKVLAVTDAGFTKKMRSLME"
     gene            18786..21578
                     /gene="infB"
                     /locus_tag="VQ862_001231"
     CDS             18786..21578
                     /gene="infB"
                     /locus_tag="VQ862_001231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-2"
                     /protein_id="HET3115587.1"
                     /translation="MSKKRLYEIAKELGKESKEVVARAKELGLDVKSHSSSVEEAVAA
                     KIAASFKPAAAPKVEAKPAAPKVSAEKKAEKSEPAKPAVAKEEAKPAEPVAPKTEKVA
                     AKPQSRNFKAEREARAKEQAERRKQNKGNNRDQQQNGNRQKNDGRNGGKQGQSNRDNR
                     RFNDQAKKQQGQQKRRNERRQQEDKRSNQVAPRIDFKARAAALKAEQNAEYARSSEER
                     FKQYQAAKEALAQANKRKEPEEIFEEAAKLAEQAQQVQAVVEVVPEKKEPAVDTRRKK
                     QARPDKNRDDYDHEEDGPRKQQKNRSSQNQVRNQKNSNWNNNKKNKKGNNKNNRNQTP
                     KPVTERKFHELPTEFEYTDGMTVAEIAKRIKREPAEIVKKLFMMGVMATQNQSLDGET
                     IELLMVDYGIEAKQKVEVDNADIERFFVEDGYLNEDELVERPPVVTIMGHVDHGKTTL
                     LDTLRNSRVATGEAGGITQHIGAYQIVENGKKITFLDTPGHAAFTSMRARGASVTDIT
                     ILVVAADDGVMPQTIEAINHSKAANVPIIVAINKIDKPGANPERVIGELAEHGVMSTA
                     WGGDSEFVEISAKFNQNIEELLETVLLVAEIQELKADPTVRAIGTVIEARLDKGKGAV
                     ATLLVQQGTLNVQDPIVVGNTFGRVRAMTNDLGRRVKVAGPSTPVSITGLNEAPMAGD
                     HFAVYEDEKSARAAGEERAKRALMKQRQATQRVSLENLFDTLKAGELKSVNVIIKADV
                     QGSVEALSASLQKIDVEGVKVTIVHSAVGAINESDVTLAEASNAFIVGFNVRPTPQAR
                     QQAEADDVEIRLHSIIYKVIEEMEEAMKGMLDPEFEEKVIGEAVIRETFKVSKVGTIG
                     GFMVINGKVARDSKVRVIRDGVVIYDGELASLKHYKDDVKEVTNGREGGLMIDCYNDI
                     KMDDVIEAYVMEEIKR"
     gene            21829..22179
                     /gene="rbfA"
                     /locus_tag="VQ862_001232"
     CDS             21829..22179
                     /gene="rbfA"
                     /locus_tag="VQ862_001232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001273594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosome-binding factor RbfA"
                     /protein_id="HET3115588.1"
                     /translation="MANHFRTDRVGMEIKREVNEILQKKVRDPRVQGVTITDVQMLGD
                     LSVAKVYYTILSNLASDNQKAQIGLEKATGTIKRELGRNLKLYKIPDLTFVKDESIEY
                     GNKIDEMLRNLDKN"
BASE COUNT         6581 a         3865 c         4883 g         6948 t
ORIGIN      
        1 aaaacggtgt tttgagcagt ctgtgcctag ctttctagtt tgctttttga tttttattga
       61 gtatgagtta cctaaattat gatgcatagt tgatgggata tatataatag attgaaatag
      121 aatatgaaca aattgataag aggattttaa agtaatctct aacaatgctt tagaaactat
      181 agtgtgctat tctaaattca attcactata acttgtttac gttttaaaaa agagccgggg
      241 ggctcttttt acttatcttc agttccctgc atttctttta tcacagctag tctagtctgg
      301 atatcctttt ccaagacctt aaacttgtaa gtcaagtctt cttggtattc cttgataagt
      361 tctttttgct ggttaatgat ttgcaggctg ttttggataa tatccacatc gtccttgata
      421 gcttgaacgc ggtcagtggt attcaagact tcatctgtga tggtttggcg attttttgta
      481 accagataac ttccggctgc agctcctgca aatagcagta ggttggataa tttcatagca
      541 actccttaag cgtttttgat ggtttcagcg acttgagcaa gtttgtcaaa gtctggttcg
      601 tgggcgataa aatcaatctt gaggtcatcg tcagcactgt agcgaggcac aaggtgaacg
      661 tgagtatgaa aaactgtttg accagcgact tcttcacagt tggaaatgat attcatacca
      721 gcagccttag tgactttcat gactttttga gctacttttg gtacttgggc aaagagttgg
      781 ctggcgctcg tagcatccat ctccaaaaga ttgcgatagt gttcttttgg cacgaccaag
      841 gtgtgtccta gtgttacttg agagatatca agaaaggcaa ggacctgctc atcttcatat
      901 acttttgaag caggaatttc ccctgcgatg attttacaaa aaatgcaatc tgacataaaa
      961 tctacctcta ctgtactgaa ttttgatata atatagctac attataccag atttggagaa
     1021 aatatgttag aaattaaaaa cctgacaggt ggctatgttc atgttcctgt tttgaaagat
     1081 gtgtccttta ctgttgaaag tgggcagttg gtcggtttga ttggtctcaa tggtgctggg
     1141 aaatcaacga cgatcaatga gattatcggt ctgttggcac cttatagtgg ctccatcaat
     1201 atcaatggcc tgactctgca aggagatgcg actagctacc gcaagcagat tggctacatt
     1261 cctgagacgc ctagtctgta tgaggaattg accctcagag agcatatcga aacggttgct
     1321 atggcttacg gtattgagca aaaagtggct ttcgaacgag tagagccctt gttaaaaatg
     1381 ttccgtttgg aacagaaatt agactggttc cctgttcatt tttcaaaagg gatgaagcag
     1441 aaggtcatga ttatctgtgc ttttgtggtg gatccaagtc ttttcatcgt ggatgagcct
     1501 ttccttggtc ttgatccgct ggctatttct gatttgattc agcttttgga agtggagaag
     1561 caaaagggca agtctattct catgagtacc cacgtgctgg attcggcgga gaagatgtgt
     1621 gatgcctttg tcattcttca caagggagag gtgcgtgcca aaggcaatct cctgcaacta
     1681 cgtgaagcct ttgatatgcc tgaggctagt ttgaatgata tttacttggc tctgaccaaa
     1741 gaggaggatc tatgaaagac ttgtttttaa agagaaagca ggcctttcgt aaggagtgtc
     1801 ttggttatct gcgctatgtg ctcaatgacc actttgtctt gttcctgctt gtcctgttgg
     1861 gctttctagc ctaccagtac agtcaactct tacaacattt tcctgaaaat cattggccta
     1921 tccttttgtt tgtaggaatt acgtctgttt tacttttact ttggggagga attgccacct
     1981 atatggaggc tccagacaag ctctttctct tagttggaga agaggaaatc aagctccatc
     2041 tcaagcgtca aactggcatt tccctagtct tttggctctt tgtacagacc cttttcttgc
     2101 tgttatttgc gcccttgttt ttagcaatgg gttatggctt gccagttttt ctgctctatg
     2161 tgcttttatt gggggtagga aaatatttcc actttcgtca aaaggccagc aaatttttca
     2221 ctgaaactgg actggactgg gactatctta tttctcaaga aagcaagcgt aagcaagtct
     2281 tgcttcgttt ctttgccctc tttacgcagg tcaagggaat ttcaaacagt gtcaagcgtc
     2341 gtgcctatct ggactttatc ttaaaggctg ttcagaaggt gcctgggaag atttggcaaa
     2401 atctctatct gcgttcttat ctgcgaaatg gcgacctctt tgctctcagt cttcgtcttc
     2461 tcttactttc cgtactggcg caggttttta tcgagcaagc ttggattgcg acagcagtgg
     2521 tagttctctt taactacctc ttgctcttcc agttgctggc cctctatcat gcctttgact
     2581 accagtattt gacccaactc tttccgctgg acaaggggca aaaggaaaaa ggcttacagg
     2641 aggtagttcg aggattgacc agttttgttt tacttgtgga agtagttgtt gggttgatta
     2701 ccttccaaga aaaactagcc cttctagcct tactaggagc tggtttggtt ttactagtct
     2761 tgtatttgcc ttatcaggta aaacgtcaga tgcaggacta acattgctga tacgacacta
     2821 aaaaagaagt tgagttcagt ctgtctcaac ttcttttttg ttactacagg ataatggttg
     2881 gtccgtagag acttatactc ttcgaaaatc tcttcaaacc acgtcagcgt cgtcttaccg
     2941 tactcaagta cagcttgcgg ctagcttcct agtttgctct ttgattctca ttgagtatta
     3001 acttggtctt gacttggtca aagtggaagc ggtcataggc ccgccaagcg gcgcgagttg
     3061 gagcatctgg atcaagagcg ctgagtccca tgagaagact ggaagtctgg taaaattttt
     3121 ccaattcaat caagaatcga ttatccactg tttcagcctt ggctagaaaa ccaagaatag
     3181 agtttaattg ctcctgaaag cggacgtcgt cagcggttgc ctgtttgcat gcttgatagg
     3241 ctttgtttaa gtcagtaatc aaagtctgag ctcttttgat agggtctgta tctgtcatga
     3301 gaattcctcc tctaatctgg gtgccagtct tgattctagc aactgtgttt tgatactgtc
     3361 agtctatcac ttttatctcc tttttcgcct ttaaatcttt aattgtcatt gaaatgtctt
     3421 gaattgcgct gagtgaattt tatgataaaa tagtggtaag ctcatcatga tattgtagaa
     3481 aaataattct tttaggagct ttcaaagact gtttaggatt gggtgtgctt gtgttagatt
     3541 ttttctgtta ttcttttctt aggaggagaa tccaatgaaa catatgatta ttcagacaca
     3601 gaaaacagtc tataaagtaa acgtcgacga tgtctactat atccaaacac atccaactaa
     3661 agcccatact gtaaagattg ttacagaaga ggctagtttt aatatggttc aaaatttaag
     3721 taatcttgag aaccaatatg gggaaacctt gatgagatgt catcgaaatt gtttggtcaa
     3781 tcttgataaa gtaaaatcga ttgattttca agaaagaatc ctttttcttg gagaagaagg
     3841 tcaatacgct gtcaagtatg ccagacgtcg ctatagagaa attcgtcaaa aatggttgaa
     3901 agaaggagag taagaagatg agaatatttg ttttagaaga tgatttttcc caacagacta
     3961 gaattgaaac gacgattgag aaactcttga aggaacatca tatcactctg agttcttttg
     4021 aagtttttgg taagccagat caattgctgg cagaggtgca tgagaagggg gcccatcagc
     4081 tattcttttt ggatattgag attcgaaatg aggagatgaa gggtctggaa gtggctagaa
     4141 agattcggga tcgggatccg tatgccctga ttgtctttgt gacgactcac tcggagttta
     4201 tgcccctgtc ctttcgctac caagtgtctg ctctggatta tattgataag gccctttcgg
     4261 cagaggagtt tgaatctcgt atcgagacag ccctcctcta tgccaatggt caagacagta
     4321 aaagtctagc ggaagattgc ttttacttta aatcaaaatt tgctcaattc cagtatcctt
     4381 ttaaagaggt ttactatctc gaaacgtcca caagacccca tcgtgttatt ctctatacca
     4441 agacagacag gctggaattt acagcgagtc tagaggaggt tctcaagcag gagcctcgtc
     4501 tcttgcagtg ccatcgctct tttctcatca atcctgccaa tgtggtgcat ttagataaga
     4561 aagaaaaact gcttttcttt cccaatggtg gaagttgtct aatcgcgcgt tataaggtca
     4621 gggaagtgtc tgaggctatt aataacttac actgagctag gagagtttat gaatgttgct
     4681 tggatattgt tgtatacact tgttactcac ggattaaaaa ttgtcatatt ctttaaggta
     4741 gatggaatta gtctcacttt tgagaggatt tttaaggcct ttctttttaa gatactgttg
     4801 gccgttgttt ttggaatgct tggctatatg gtaggaaatg tttacctatc ttattttatg
     4861 gaacccttgt acggcatagg cttatctttc ttattgttaa gagaacttcc taaaaaactc
     4921 cttctctttt atggtctctt tccaatgata ttagtgaatc tcttttatag aggtgtttcc
     4981 tattttgtgc ttccattttt gggacaaggg caagtatatg atgactactc atttatttgg
     5041 ttatgtataa taattttcaa tttcttcatt tctctagctt ttttgaaatg gttggactat
     5101 gatttcacta gcttgagaaa ggggattctc gataaagatt ttcaaaagtc cctgactcag
     5161 attaactgga taatgggggc ttactatttg gtgatacaaa atctgtctta ctttgaatat
     5221 gaacagggga ttcaatcaac gactgttcgc catctcatcc tagtctttta cctgctcttt
     5281 tttatgggga ttatcaagaa attggatacc tatttgaagg acaaactcca tgagagactg
     5341 aaccaagagc aggacttgcg ctacagagag atggagcggt atagtcggca tatagaggag
     5401 ctttataagg aagtacggag ttttcgccat gactacacca acctcttgac tagcttacgt
     5461 ctgggcattg aagaggagga tatggagcag ataaaagaga tctacgactc ggtcttaaag
     5521 gattctagtg aaaaattgca ggacaataaa tatgaccttg gccgattggt gaatgttcgg
     5581 gatcgtgccc tcaaaagtct cctagctgga aaatttataa aagctagaga taagaacatt
     5641 gtctttaatg tcgaagttcc agaggagatt caggtagagg gggtgagtct acttgatttt
     5701 ctaaccgttg tgtctatcct ttgtgacaac gctattgaag ctagtgtaga agcctgtcaa
     5761 cctcatgttt caattgcctt ttttaaaaat ggagcacagg agacctttat cattgaaaat
     5821 tccatcaaag aagagggaat cgatatttct gaaatcttct cctttggagc aagttctaaa
     5881 ggggaggaga gaggagttgg tctctatacc gttatgaaaa ttgtggaaag tcatcccaat
     5941 accagtctca ataccacctg ccaagatcac gtttttcgtc aggtacttac tgtaatacat
     6001 atagaatgaa gaaaaaataa gaccgagagt gcgttctctt ggtcttgttt ttttatagtt
     6061 gtattggctg ataaaatcct tttgtatttt tttgttcaat tatattaaat ctatataaga
     6121 aatcttccca ccatcctcca cctataattt ggttgagttc ggtagttgtt agttcttgaa
     6181 atgaagttag gttttgtttc ttatccatgt tatgattctc ctttttgata agataataaa
     6241 tagttataga gtgttatctg aaaattaatc agaatgggtt aaaattttat ctttgaaata
     6301 atcaaaatat gttttctttg tagttacact agtgacgcga ccttgtaagc catattggat
     6361 gagtttacta tcctcgttag atagttttgc aagagcggtt aatttaaaga gattgccttg
     6421 ctctgttctg gtaggagttt gatcaatact ctgaagttgg ccgatgatgg tggtgccgtg
     6481 atttccaatc ttctccagtt ttaatcttac agtttgtcct ttatctagta aggggagata
     6541 gtcagatgat acgtagtaag tgattagtac ttctcttgta tctgtgatga cagggaatat
     6601 ttgagcaatt tctgtaccag ttggaattct atttttacct tcaaattcgc tgttcagatg
     6661 aacgatacct ttacttggag cggttaaggt attattttct aagcgctgtg tcgcttgatc
     6721 tagttgtact tttaattctg ttaattgatt ctccacggtt agttgttgct gtgaggctgt
     6781 ttgtaaaaac tgagtgcgga gtacttcaat tttggttgct aaactattat cataagttgc
     6841 tacacttccg ataccagctt gctgaatttt gatgcttgcg atagatgatt caagacttgc
     6901 aatactttga ttaatttgag ataaaaatgg ctcctctgcc gttccttgtg tttgtccttg
     6961 agaggctata agataacgat ttaaaattga ctggtgcgga ttgccagttg gtaagcgtgc
     7021 tctgttattt atgatagcat ctctcaactc ttgatattct ccaatttgtt gttgaacttt
     7081 tgtaatttct tgttcgatgg ctgatgaact gctattggta agattagctt gatttgaaac
     7141 ttcagtgtta gtctttgaga tacccagttc aatatcatgg gattgtttag taaaattcat
     7201 aaaggtatta tggtagccaa actcatcctc gctagaaaaa agatcagtcg ctttttctaa
     7261 gctttgtttc aagattccaa gtccttcttt ttgcttctca agtctttgta attgagttgc
     7321 taaggcagtt ttctgacttt cttccattgt ttcagagtat ttgatgagta agtcaccttt
     7381 ctcaactact tgatttgcca ctaaatgatt agcaaggata ggattatcac tggtcgactg
     7441 aatagatgca atgacacttg taggggcgat ttctccttgg gaagtaacag taatttcttt
     7501 tgtggcaaca agggagaaaa tcaagatgaa agtaaatagt aatgaaagag gtataatgaa
     7561 cactgtcgca tagttatggt aacgtctctg ataaaactcg acacttctaa aaagattagg
     7621 attcatgaca ttctccttat ttattgaata gatgatggta gaagccttgc gcctgcatta
     7681 actcttggtg actaccaact tcaatgattt tcccctggtc aagaacaatg acacggttag
     7741 ttcgttcggc tatactgaga cgatgggcta caaagagaat ggttttatca gttagggata
     7801 taagattatc tataaccttt ttctcagtca agacatcaag accgctagta gcttcatcta
     7861 gtattaaaac aggagcttta gttaaaagag cacgagcgag agcgattcgt tgcttttgtc
     7921 ctcctgatag accagctcca tcagagagct gagtttgata gcccataggc attctttcaa
     7981 tgtcttgacg gatttcagct aattcacaag ctcttagaat atcttcttgg ctaatcatat
     8041 gattaccgcc caaggttaaa ttttccaaga tagagccatt aaagatatag gcttgttggg
     8101 gtaggtaatt aatatgacgg cgcaagactt ttttatcaat gtttttaata tcctgataat
     8161 tgatggaaat atgccctttg tagggttcaa agaaattgac aatcattttg gctaaagttg
     8221 ttttaccaga accactaact ccaactaggc taaccttatc tccttgttta atcgtgagat
     8281 taatatctgt taaggtatct cgtccaaaac catacttata agaaaggtca tcaaattcaa
     8341 tatcgcccat caaaaaatgt gaatgaacag ggttttcttg aacttgaaat tcagattcga
     8401 ctagatagac ttcgttcaaa cggttattag cgaccttcgc agattggagt ttggtttgga
     8461 ggttgataat attttccata ggagttgtaa agtaagaaaa aagtgtgtta aaggtaatca
     8521 gctgaccgat agaaatttta ctcgacatga ctaattgagc gccaaaccat aggataagga
     8581 tattcagaac taattttgtt ccctgcttta aactcgtttg taaaatagaa tatttactga
     8641 gcttaaagga tttttccaaa taatctacaa attcgctgtc tatattttga tagcgatttt
     8701 cttcactcgt gagcgacttt atagtttcaa tcccgttgat atcttcgata atggcagagc
     8761 taaccataga attactttgc atgacatcat ggttcatttt ttcgaaaggt ttcataaaag
     8821 aaaagatgat gaacatgtat ataggaatgg aaagaagaga aaggaggaag agattagggt
     8881 tttgtgccag taagacgccc cctacaagaa tcagaataga aacatccaga aaaagagaaa
     8941 gaatggtaga agccaaggca tctataatag agttagcatc tgtgaaccgt gaaatgattt
     9001 ctcctgtacg acgtgtcgca aagaaagaca tgggaagttc aaaaatatgg cgaatatagg
     9061 ataaaatcac atcaatgctt aatctctggc tcagaacggt taggagataa tctctggaaa
     9121 agctcatgac ttgttggagg atataggtga taaccagacc aactgagatg attcctaaag
     9181 ttgatttcat ctgatttggg atgtattcat ccaagattcc ttggagataa taagaaccac
     9241 cgatattgat aatagtgacc aataagcttg agagaacaat gtaagcaatg agagattttt
     9301 gtttgaaaat cagaggaagg aagcttagta gaccattctt tttatcttta tggggttgat
     9361 agctgggttt gggagctaga aaaatagcta ctccagtcca ttcagagaaa aagcgttctt
     9421 ttgacatttt agtgattttt acagaagggt caggatcacc aataatcaga tagtctttct
     9481 ttgtttgata gacaacatag taatgttgga gttttccttc tttgttaacg tgaacgataa
     9541 atggataggg gacatcactc atgtcaaaga gagttttatc tgcttgaaca ggccttgttt
     9601 caaagcccat ttcatcagcg gcttttacaa tgccaagagc agtcgtccct tctttattgg
     9661 tctttgcaag ttctctcaag tgagctagag aaaaatctga accatagaat ttagcaatcg
     9721 aggctaaggc agcaacaccg cagtctctag catctatttg aggaacaaat gtacgtttat
     9781 aagaagtcat tggcaattcc tttcatatag tggatagctc tattatgaca taaaaacaat
     9841 ttcgtgcttt ataaaatctt gaatagtcat tgaaatttcc tgaatggtaa aaaagtgatt
     9901 agaaattatc ttttaaaaaa aatttagagg tagttttaaa taaaaaagct aatttaagac
     9961 gtttcgatga caattcaaga tttggatgaa aaactttaac aaatagtgct atactaaact
    10021 tgtcaaagtt gcaacaagac aaaaattaaa aataaaaaag gagtatttgt tatgaataca
    10081 aaaatgatgg aacaatttca tgaaatggat atagctatgt tatctagtat tgaaggaggc
    10141 aagaataatt ggcaaactaa tgttttcgaa ggtggtagtg ctgcttttgg tggctggggg
    10201 ttagggacag ctatttgtgc tgcgagtggt gttggagcgc catttatggg agcatgtgga
    10261 tacataggag ctaaatttgg tgtggctctt tgggcaggag taacaggggc aacgggtgga
    10321 ttttaacaaa aggagacttg tatgaatact tattgtaata taaatgaaac aatgctgagt
    10381 gaggtttacg gaggtaattc cggaggagca gctgtagttg ctgctttagg ttgtgcagcg
    10441 ggtggagtga aatatgggaa aattctagga ccatggggcg ctgcaatagg aggaattgga
    10501 ggagcagtgg tttgtggata tttagcctat accgctacat cataaaaatg aaagctaaat
    10561 tttatgaagg ctatattctt tattattctc ttcgcttttc aaacctatct tatttatcta
    10621 tccataagta tctctgataa aaaacaaaag actattgaat taacatcatt gaattgtttt
    10681 gtcatattat ttctaatcta tgataaatta atttttctct ttattgccta tgtttttttg
    10741 ataattttta tattaaactt gttccgtaac tgaaaagtga catactatat gaatacaaaa
    10801 atgatgtcac aattttctgt tatggataat gaaatgcttg cttgcgttga aggtggagat
    10861 attgattggg gaagaaaaat tagttgtgca gcaggggttg catatggcgc aattgatggg
    10921 tgtgcaacaa cggtttgaca tttctattgg gaccatttgc tataggaata ggtgtaactg
    10981 gtgctgcagg tggagctata cttggaggtg tagcctatgc agcaacatgt tggtggtaat
    11041 tatggatttt aaaagtttta ttattggttt agtagttggt atatttggtc cttatatgga
    11101 tgacttaatt agaaaaatat tttcaaaatc ttccaaaaag gatacggata gtactctcta
    11161 aaaaataaat ttctcccctg tatttgctag cttaatttac aggggagttt ctttaatatt
    11221 gtttcgcctg tcaaaatgat atgtgatagc aggatgaaaa gtctacaaac aagttggtat
    11281 caatacaata taaagaggaa agtatgtttt tcatgcttgc ttttttaatt tttacaattc
    11341 aagaggtttt gatgaccatt tatgatttga gtgatccaag gtcaaaataa gtgctatact
    11401 agcagtgtaa atgttcttgc tcaactaaga taaatcgcac atttaggagg aaatcttatg
    11461 aagaaaaaaa tactgattat tttcgttctg tatctgatca tgtccatctt tctttatccg
    11521 cttagggaga gtatttggta taatctattt tataccatag cctatatgat tgcggttatg
    11581 atctattttt ctttaattaa aaagaaagaa aagaaatgaa agattttctt gattaaaaag
    11641 aatcatattc tttgtgagat tgttcctggg tcagttgcct ttgcttgttt ctacttatct
    11701 atttctattt cgtcagtttt ccaatttctt ttagtggtta ttaacttagc ttctattttg
    11761 gtcactgttt acctcactag ggaaatgcgg ataaaagagt ttgaagatga tgatttggtt
    11821 agtcctagaa ccaatcaact tatgttcatc ggcttgacag gctttatgtc tattatttgt
    11881 ttgtatagag ggatcacagc aggagaatcc taccaacaaa taatcgctta tattggcgct
    11941 attctctgct tgaccatcat gcttctgctc atttggggat tgaagtatta taaaaagtag
    12001 aggctaatgc agtttttgca atttaagatg tcttgatgac aattcaagat ttggatgaaa
    12061 aactttgaca aatagtgcta tactgaaatt gtcaaagttg caacgggtgc tgctacatta
    12121 tgttaaaaat cgctcttgat tgataagttg gatttgttag gaaaggagta aataattatg
    12181 gataagaaaa agatagtttc gactataata tgtatagtat ttcttgtagt gtcagtagat
    12241 aattttttta gagacttaac cccgttactg ttcattttaa atattattgg cctgtcttgc
    12301 ttttcagtgc taacatacat taacataaaa gagatactct taaatataag taaatgatga
    12361 tttggttagt cctagaacca atcaacttat gtttatcggc ttggcagatt ttatgtttgt
    12421 catttgtttg tatagaggta tttcagaaac agaattctat caacaactaa tcgcttatat
    12481 aggtgtattc tctgcttgtt tatcacgctt ctgctcatgt ggggcttgaa gtattataaa
    12541 aagtagcttt ctatcctttt ctgacaggat atttgagtag aaggctctat taaattgtta
    12601 gtgaaataaa tgaatggagg tatttaatat gaaatacaga ttattttttg ttattttctt
    12661 gagtagtgtg ttggatattc ttttagggac atttttacaa atctctatcg tatctattgg
    12721 gtggcttgtt ctttacagtg gtttgtttga agcaggagtt ttccttcttg ctaataaagg
    12781 ggtggcggta aaaatcaagg aagtagatat tcgaaatcgc tttaaattta tttttggaaa
    12841 aaccttatgg tttcaaattc ttttgctcat ctttttgata atcaaacttt atcttggttt
    12901 ggatgcgagg ttgattttat tctatggaca tattttcatt gtctttaatg ccttaatgta
    12961 tctattatct agtagtcagg ttagccttaa aaaaaacaaa ctgtcttctt aatcttacag
    13021 cagtagagcc tgacaaggtg aggtcatagt agggaggatt tctatgaaaa agtatcaact
    13081 tctattcaaa ataagtgcag ttttctctta cttatttttc gtatttggtc tttctcagat
    13141 gacgcttatt attcaaaatt attggcaatt ttcttcccag attggcaatt tcgtctggat
    13201 tcaaaatttc ttgagtttgc tatttagcgg agtcatgatt tggattctgg ttaagacagg
    13261 tcatggttat ctctttcaca ttccaagaaa aaaatggctt tggtattcga ttttgacagt
    13321 attagtggta gtgctccaga tctcttttaa cgttcagaca gctaaacatg ttcagtcaac
    13381 tgctgaaggt tgggctgtat tgatcggtta tagtgggacc aactttgctg agctaggtat
    13441 ctatataact ttgttctttc tgactccact tatggaagag ctaatctata gaggattact
    13501 gcaacacgcc ttttttaagc attcgagatt tggccttgat ttgcttcttc cgtcaatttt
    13561 atttgctctt cctcattttt caagcctgcc tagtttgtta gatatcttca tctttgcaac
    13621 atctggcatc atctttgcta gtttgacccg ctataccaag agcatttatc cttcctatgc
    13681 ggtgcatgtg atcaataata ttttcgcaac attaccattt ttgctgactt ttttacatag
    13741 ggtcttgggg taaaaaaaca aaaggcttgc ttttcagcca tagaggagat tatcatgtat
    13801 aaacacttat ttttcctaga ttccaaaact ttagatcggt tgacacccta tattctagtc
    13861 ttggcttctg acaccattgc ttttaatgtt tttgtgctaa cctttgtatc tgcggtggtt
    13921 tttaatttcc taaattccat gctagcttta atggctatat tcataggggc tggctatgtg
    13981 gtcggatttt ggttactaat actcaatgaa aatcaaagag caaactagga aactagccgc
    14041 aggctgtact tgagtacggc aaggcgacgt tgacgtggtt tgaatttgat tttcgaagag
    14101 tataaaatgg tttgttttgg aaaggctaga actaaagaat gacgcgtagg aagtctgttt
    14161 ggtgaggagg atagttttat ggagtttttt gataaatttc atgccttgtg ttttggattt
    14221 ttagtactaa taattgtcat tacagttcct tatacgatta accatggggt tttttttcaa
    14281 aatgaatctg cattgattct tgtaagtctt cttgtaacct cgctgagtgt tgcttatgct
    14341 agaaagtttg aaatgatttc ttttgggatg ttaagcaaga aacaactttt gcttttcatt
    14401 gcaatctttc ttctaagtgt acttgagacg ctggtttata ttcatttctt cgctgtttct
    14461 tctggctcag gggtccaaca cttggcggaa gtcagcagag gaatttccct gtctttgatt
    14521 ttgactacct cagtttttgg ccccatccag gaggaactca ttttcagagg acttcttcaa
    14581 ggtgcggttt ttgacaattc ttggttaggg cttgtgctaa cttcctctct cttttctttc
    14641 atgcatggac cttctaatgt cccttcgttt attttttatc tacttggggg tttgttgctg
    14701 ggctttgctt ataaaaagag tcaaaaccta tgggtttcta ctctagtcca catgttttac
    14761 aacagttggc cactcctata ttatttataa aaattatgaa aaggtaagca gaagatggtg
    14821 cttacctttt tcaagctata atgataccca agccaatcca gaggcttttc tttgagaatc
    14881 gggttagagt ggttgacgaa taggccaaaa actagtagaa tagtaaggaa actttatacg
    14941 gaggaaagaa atggatttgg gtgataatga gctaacactg actcccatac ctgggaaaag
    15001 tggcaaggct tatatgggta gctatcctga cgggaagcgc atctttgtaa aaatgaacac
    15061 ctctccaatc ctacctggtc tagctagaga acaaattgct ccacaattat tatggagtcg
    15121 tcgtttggca gatgggcgtg atatgtgtgc tcaagaatgg ttgacaggca agatattgac
    15181 cccctatgat atgaatcgta agcaaatcgt caatatttta acccgtcttc atcgctcacg
    15241 tccgttgatg acacaattga gtcgtttggg ctatgccatg gaaacacctg tagatttact
    15301 acagtcttgg caggaaacgg ctccagatgc tttgcgtaaa aatcatttta tcagtgaagt
    15361 gatggctgat ttacgtcaga ctattccagg atttagagag gaccatgcga ccattgtcca
    15421 tggagatgta cgacatagta attggattga gacagatagt ggcttgattt atttagtaga
    15481 ttgggattcg gttcgcttga ccgatcgcat gtttgatgtg gcccatatgc tctgccatta
    15541 tatttcagaa catcagtgga aggaatggtt gacctactac ggttacaagt acaatcaaac
    15601 ggtattaagt aaattgtatt ggtatggtca attgtcttat ttgagtcaga tttccaagta
    15661 ttatatgaac caagatttag aaaatgtcaa tcgggagatt catggtttgc gtcatttccg
    15721 agacaagtat ggaaagagaa gatgagagtt agaaatcgta aaggggcaac agaattacta
    15781 gaggcaaatc cccagtatgt ggtcctcaat cccttggaag ccaaggcaaa atggcgggac
    15841 ttgtttggca atgataatcc cattcatgtg gaagttggaa gtggaaaggg tgcctttgtt
    15901 tcaggtatgg ccaagcaaaa ccctgacatc aactatatcg ggattgatat tcaaaagtct
    15961 gttttgagct acgctttgga caaggtgctt gaagttggag tgcctaacat caagctcttg
    16021 tgggtagatg gttctgactt aactgactac tttgaagacg gtgagattga tcgcttgtat
    16081 ctgaactttt cagatccatg gccgaaaaaa cgccatgaaa agcgtcgttt gacctacaag
    16141 accttcttgg ataccttcaa acgtatcttg cctgaaaatg gagaaattca tttcaagacg
    16201 gataaccgtg gcttgtttga gtacagttta gtgagctttt ctcaatatgg catgaaactc
    16261 aatggtgtct ggttagattt gcatgccagt gattttgaag gcaatgtcat gacagaatac
    16321 gagcaaaaat tctcaaacaa ggggcaagtt atctaccgag ttgaggcaga attttaagag
    16381 atagcctaaa attaggctgt acaagtgctt ttgctttaca taagttggca aacgtgctat
    16441 actgatagta agaatatgaa aagtgaggcg gggaaatatc ttcgcctctt gcttatgagg
    16501 aggtggacgc aatcgcaaca atcgtagaat tagtcagaga agttgtagaa cctgtcatag
    16561 aagctccttt tgaactcgtg gatatcgagt atggaaagat tggcagtgac atgattctca
    16621 gtatttttgt agataaaccc gaaggaatta ccttgaacga cacggcagac ttgacagaaa
    16681 tgatcagtcc tgtcctagac accatcaagc cagatccctt cccagaacaa tatttcctag
    16741 aaattaccag tccaggtttg gaacgtcctt tgaaaaccaa ggatgccgtc gctggagcgg
    16801 ttggaaaata catccatgtc gggctctacc aagccatcga taagcaaaag gtctttgaag
    16861 gaaccttgtt ggccttcgaa gaggacgagt tgactatgga atatatggac aagacgcgta
    16921 agaaaaccgt ccaaattcca tacagtttag tatcaaaagc acgtttagca gttaaattat
    16981 agaaaaagaa aggatagctt ttgaggattc aaaagtgaag aaaacatgag taaagaaatg
    17041 ctagaggcct tccgcatttt ggaagaagac aagggaatca aaaaagaaga tatcatcgac
    17101 gcagtagtag agtcgcttcg ttccgcttat cgcagacgct atggtcagtc agacagcgta
    17161 gctattgact tcaacgaaaa aacaggtgac tttacagttt atactgtccg tgaagttgtt
    17221 gatgaagtat ttgatagccg tttggaaatc agcttgaaag atgctcttgc cattaattca
    17281 gcttatgaac ttggagacaa aatcaagttt gaagaagcac cagctgagtt tggtcgtgta
    17341 gcagcccaat ctgccaaaca aaccatcatg gaaaaaatgc gcaagcaaac acgtgccatc
    17401 acttacaata cttacaaaga acatgagcaa gaaatcatgt ctggtacagt agaacgcttt
    17461 gacaaccgct ttatctatgt caaccttggt agcatcgaag cccaattgtc aaaacaagac
    17521 caaattcctg gagaagtttt tgcttctcat gatcgtatcg aagtttatgt ttacaaggtt
    17581 gaagacaacc ctcgtggtgt gaacgtcttt gttagccgta gccatccaga aatgatcaaa
    17641 cgtttgatgg agcaagaaat tccagaagtt tatgatggaa ctgttgaaat catgagcgtg
    17701 gctcgtgaag caggtgaccg tacgaaggtt gctgttcgta gccacaatcc aaacgtggat
    17761 gctatcggta caatcgttgg acgtggtggt gctaatatca agaagattac tagcaaattc
    17821 cacccagctc gttacgatgc taaaaatgac cgcatggtac caatcgaaga aaatatcgat
    17881 gttatcgagt gggtagcaga tccagctgaa tttatctaca atgccatcgc tcctgctgag
    17941 gttgaccaag ttatctttga tgaaaacgac agcaaacgtg ccttggtggt tgttccagat
    18001 aacaagcttt ctcttgccat tggtcgtcgt ggacaaaacg tgcgcttggc ggctcacttg
    18061 actggttacc gtatcgatat caagtctgct agcgaatttg aagccatgga agacgctgct
    18121 tcagtagagt tggaagtaga aaacgatact gtagaagaat aaaagctgct agaggaggga
    18181 aagatgaaaa caagaaaaat ccctttgcgc aagtctgttg tgtctaacga agtgattgat
    18241 aagcgtgatt tgctccgcat tgtcaagaac aaggaaggac aagtctttat tgatcctacg
    18301 ggcaaggcca atggccgcgg cgcttatatc aaactagaca atgcagaagc cctagaggcg
    18361 aaaaagaaga aggtctttaa ccgcagtttt agcatggaag tggaagaaag cttttatgac
    18421 gagttgatcg cttatgtgga tcacaaagtg aaaagaagag agttgggact tgaataagca
    18481 aaagataagt aatctcttgg ggcttgctca gcgagcaggg cgcatcatat cgggtgaaga
    18541 attggtggtc aaggccattc aagacggcaa ggccaagttg gtctttctag ctcatgatgc
    18601 tggacccaat ctgaccaaga agattcaaga taaaagtcat tattatcaag tagaaattgt
    18661 aaccgtgttt tcaacactgg aattaagcat agcagtcggg aaatcgagaa aggttttggc
    18721 tgtaacagat gctggattta caaagaaaat gaggtctctt atggaataga agaggaggac
    18781 atgatttgtc taagaaaaga ttgtacgaaa tcgcaaaaga acttggaaaa gaaagtaaag
    18841 aagttgtagc gcgtgcaaaa gagttgggct tggatgtgaa aagccactca tcaagtgtgg
    18901 aagaagctgt cgctgcaaaa attgctgcca gctttaagcc tgcagctgct ccgaaagtag
    18961 aagcaaaacc tgcagcacca aaagtaagtg cagaaaagaa agccgaaaaa tctgagccag
    19021 ctaaaccagc tgtagctaag gaagaggcaa aaccggctga gccagttgct ccgaaaacag
    19081 aaaaagtagc agcgaaaccg caaagccgta atttcaaggc tgagcgtgaa gcccgtgcta
    19141 aagagcaggc agaacgacgc aagcaaaata agggcaataa ccgtgaccaa caacaaaacg
    19201 gaaaccgtca gaaaaacgac ggccgtaatg gtggaaaaca aggtcaaagc aaccgcgaca
    19261 atcgtcgctt taatgaccaa gctaagaagc agcaaggtca gcaaaaacgt agaaatgagc
    19321 gccgtcagca agaggacaaa cgttcaaatc aagtggctcc acgtattgac tttaaagccc
    19381 gtgcagcagc cctaaaagca gagcaaaatg cagagtacgc tcgttcaagt gaggaacgct
    19441 tcaagcagta tcaggctgct aaagaagcct tggctcaagc taacaaacgc aaggaaccag
    19501 aggaaatctt tgaagaagcg gctaagttag ctgaacaagc acagcaagtt caagcagtgg
    19561 ttgaagtcgt ccctgagaaa aaagaacctg cagtggatac acgtcgtaaa aaacaagctc
    19621 gaccagacaa aaatcgtgac gattatgatc atgaagaaga tggtcctaga aaacaacaaa
    19681 agaatcgaag tagtcaaaat caagtgagaa atcaaaagaa tagtaactgg aataacaaca
    19741 aaaagaacaa aaaaggcaat aacaagaaca accgtaatca gactccaaaa cctgttacgg
    19801 agcgtaaatt ccatgaattg ccaacagaat ttgaatatac agatggtatg accgttgcgg
    19861 aaatcgcaaa acgtatcaaa cgtgaaccag ctgaaatcgt taagaaactt ttcatgatgg
    19921 gtgtcatggc cacacaaaac caatccttgg atggggaaac aattgaactc ctcatggtgg
    19981 attacggtat cgaagccaaa caaaaggttg aagtggataa tgctgacatc gaacgtttct
    20041 ttgtcgaaga tggttatctc aatgaagatg aattggttga gcgtccacca gttgttacta
    20101 tcatgggaca cgttgaccac ggtaaaacaa cccttttgga tactcttcgt aactcacgtg
    20161 ttgcgacagg tgaagcaggt ggtattactc agcatatcgg tgcctaccaa atcgtggaaa
    20221 atggtaagaa gattaccttc cttgatacac caggacacgc ggcctttaca tcaatgcgtg
    20281 cgcgtggtgc ttctgttacc gatattacga tcttggtcgt agcggcagat gacggggtta
    20341 tgcctcagac tattgaagcc atcaaccact caaaagcagc taacgttcca atcatcgtag
    20401 ccattaacaa gattgataaa ccaggtgcta acccagaacg cgttatcggt gaattggcag
    20461 agcatggtgt gatgtcaacc gcttggggtg gagattctga atttgttgaa atctcagcta
    20521 aattcaacca aaatatcgaa gaattgttgg aaacagtcct tcttgtagct gaaatccaag
    20581 aactcaaggc agacccaaca gtgcgtgcaa tcggtacggt tatcgaagcg cgcttggata
    20641 aaggaaaagg tgcggtcgca acccttcttg tacaacaagg taccttgaat gttcaagacc
    20701 caatcgttgt cggaaatacc ttcggtcgtg tccgtgctat gaccaacgac cttggtcgtc
    20761 gtgttaaagt tgctggacca tcaacaccag tctctatcac aggtttgaac gaagcaccga
    20821 tggcgggtga ccactttgcc gtttacgagg atgaaaaatc tgcgcgtgca gcaggtgaag
    20881 agcgtgccaa acgtgccctc atgaaacaac gtcaagctac ccaacgtgtt agccttgaaa
    20941 acctctttga tacccttaaa gctggggaac tcaaatctgt taatgttatc atcaaggctg
    21001 atgtacaagg ttctgttgaa gccctttctg cctcacttca aaagattgac gtggaaggtg
    21061 tcaaagtgac tatcgtccac tcagcggtcg gtgctatcaa cgaatcagac gtgacccttg
    21121 ccgaagcttc aaatgccttt atcgttggtt tcaacgtacg ccctacacca caagctcgtc
    21181 aacaagcaga agctgacgat gtggaaatcc gtcttcacag cattatctac aaggttatcg
    21241 aagagatgga agaagctatg aaagggatgc ttgatccaga atttgaagaa aaagttattg
    21301 gtgaagcggt tatccgtgaa accttcaagg tgtctaaagt gggaactatc ggtggattta
    21361 tggttatcaa cggtaaggtt gcccgtgact ctaaagtccg tgttatccgt gatggtgtcg
    21421 ttatctatga tggtgaactc gcaagcttga aacactataa agacgacgtt aaggaagtta
    21481 caaacggccg tgaaggtgga ttgatgatcg actgctacaa tgatattaag atggatgatg
    21541 tgattgaggc gtatgtcatg gaagaaatca agagataaga ttttttgctc ctttcttagg
    21601 tggtgaggga cgcaagcaaa ccgatggttt cattgcttat ttttgagcct agggtctcaa
    21661 aaatcccctg tgatgggact gataaatcag ttccatcact ttcaccacgg cgaaagaagc
    21721 agatgacttc aaattgaact tcgtttcaat ttaaactgaa aatcaagaag tttaaaatag
    21781 ctaggtctgc tggcctagct tttggttcaa agtagagaaa ggaatatcat ggcaaatcat
    21841 ttccgtacag atcgtgtggg catggaaatc aagcgtgaag tcaatgagat tttgcaaaag
    21901 aaagtccgtg atccacgtgt ccaaggtgtg accatcacag atgttcagat gctgggtgac
    21961 ttgtctgttg ccaaggttta ttacaccatt ttgagtaacc ttgcttcgga taaccaaaaa
    22021 gcccaaatcg ggcttgaaaa agcaactggt accatcaaac gtgaacttgg tcgcaatttg
    22081 aaattgtaca aaatcccaga tttgaccttc gtcaaagacg agtccatcga gtatggaaac
    22141 aagattgacg agatgctacg caatctggat aagaactaaa gaagaggggt tgcccctctt
    22201 ttttggtgga ggaaaatagg ttgaatttga aatggaaaaa tattctttta taatagtttg
    22261 aaactagaat agtacgc
//
LOCUS       DAVBOD010000029        22120 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 640-05
            SAMEA1012484-rid20186543.denovo.029, whole genome shotgun sequence.
ACCESSION   DAVBOD010000029 DAVBOD010000000
VERSION     DAVBOD010000029.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012484
            Sequence Read Archive: ERR059358
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 22120)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22120)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979948.1
            Genome Coverage       :: 595x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:03:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,266
            CDSs (total)                      :: 2,219
            Genes (coding)                    :: 2,091
            CDSs (with protein)               :: 2,091
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 71 of 128
            Pseudo Genes (incomplete)         :: 50 of 128
            Pseudo Genes (internal stop)      :: 33 of 128
            Pseudo Genes (multiple problems)  :: 22 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22120
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012484-rid20186543.denovo.029"
                     /strain="NIG 640-05"
                     /db_xref="taxon:1313"
     gene            1..267
                     /locus_tag="VQ862_001233"
     CDS             1..267
                     /locus_tag="VQ862_001233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000962022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComGC"
                     /protein_id="HET3115589.1"
                     /translation="MLVVLLIISVLFLLFVPNLTKQKEAVNDKGKAAVVKVVESQAEL
                     YSLEKNEDASLSKLKDDGRITEEQVKAYKEYNDKNVGANRKVND"
     gene            260..664
                     /locus_tag="VQ862_001234"
     CDS             260..664
                     /locus_tag="VQ862_001234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000588002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system protein"
                     /protein_id="HET3115590.1"
                     /translation="MIKAFTMLESLLVLGLVSILALGLSGSVQSTFAAVEEQIFFMEF
                     EELYRETQKRSVASQQKTSLNLDGQTISNGSQKLPVPKGIQVPSGQSITFDRAGGNSS
                     LAKVEFQTSKGAIRYQLYLGNGKIKRIKETKN"
     gene            669..929
                     /locus_tag="VQ862_001235"
     CDS             669..929
                     /locus_tag="VQ862_001235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000601743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3115591.1"
                     /translation="MILLEAVVALAIFASIATLLLGQIQKNRQEEAKILQKEEVLRVA
                     KMALQTGQNQVSINGVEIQVFSSEKGLEVYHGSEQLLAIKEP"
     gene            892..1353
                     /locus_tag="VQ862_001236"
     CDS             892..1353
                     /locus_tag="VQ862_001236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000250539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComGF"
                     /protein_id="HET3115592.1"
                     /translation="MVQNSCWQSKSHKVKAFTLLESLLALIVISGGLLLFQAMSQLLI
                     SEVRYQQQSEQKEWLLFVDQLEVELDRSQFEKVEGNRLYMKQDGKDIAIGKSKSDDFR
                     KTDASGRGYQPMVYGLKSAQITEDNQLVHFRFQFQKGLEREFIYRVEKEES"
     gene            1331..1744
                     /locus_tag="VQ862_001237"
     CDS             1331..1744
                     /locus_tag="VQ862_001237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComGF"
                     /protein_id="HET3115593.1"
                     /translation="MWKKKKVKAGVLLYAVTMAAIFSLLLQFYLNRQVAHYQDYALNK
                     EKLVAFAMAKRTKDKAEQESGEQVFNLGQVSYQNKKTSLVTTVRTSKSQYEFLFPSVK
                     IKEEKRDKKEEVATDSSEKVEKKKSEEKPEKKENS"
     gene            1881..2475
                     /locus_tag="VQ862_001238"
                     /pseudo
     CDS             1881..2475
                     /locus_tag="VQ862_001238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000679792.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
     gene            2536..3489
                     /locus_tag="VQ862_001239"
     CDS             2536..3489
                     /locus_tag="VQ862_001239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000345081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HET3115594.1"
                     /translation="MDFEKIEQAYTYLLENVQVIQSDLATNFYDALVEQNSIYLDGET
                     ELNQVKDNNQALKHLALRKEEWLKTYQFLLMKAGQTEPLQANHQFTPDAIALLLVFIV
                     EELFKEEEITILEMGSGMGILGATFLTSLTKKVDYLGMEVDDLLIDLAASMADVIGLQ
                     AGFVQGDAVRPQMLKESDVVISDLPVGYYPDDAVASRHQVASSQEHTYAHHLLMEQGL
                     KYLKSDGYAIFLAPSDLLTSPQSNLLKVWLKEEASLVAMISLPENLFANAKQSKTIFI
                     LQKKSEIAVEPFVYPLASLQDASVLMKFKENFQKWTQGTEI"
     gene            3540..4730
                     /locus_tag="VQ862_001240"
     CDS             3540..4730
                     /locus_tag="VQ862_001240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate kinase"
                     /protein_id="HET3115595.1"
                     /translation="MTKTIAINAGSSSLKWQLYLMPEEKVLAKGLIERIGLKDSISTV
                     KFDGRSEQQILDIENHTQAVKILLDDLIRFDIIKAYDEITGVGHRVVAGGEYFKESTV
                     VEGDVLEKVEELSLLAPLHNPANAAGVRAFKELLPDITSVVVFDTSFHTSMPEKAYRY
                     PLPTKYYTENKVRKYGAHGTSHQFVAGEAAKLLGRPLEDLKLITCHIGNGGSITAVKA
                     GKSVDTSMGFTPLGGIMMGTRTGDIDPAIIPYLMQYTEDFNTPEDISRVLNRESGLLG
                     VSANSSDMRDIEAAVAEGNHEASLAYEMYVDRIQKHIGQYLAVLNGADAIVFTAGVGE
                     NAESFRRDVISGISWFGCDVDDEKNVFGVTGDISTEAAKIRVLVIPTDEELVIARDVE
                     RLKK"
     gene            4879..5250
                     /gene="rnpA"
                     /locus_tag="VQ862_001241"
     CDS             4879..5250
                     /gene="rnpA"
                     /locus_tag="VQ862_001241"
                     /EC_number="3.1.26.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000739244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P protein component"
                     /protein_id="HET3115596.1"
                     /translation="MKKNFRVKREKDFKAIFKEGTSFANRKFVVYQLENQKNHFRVGL
                     SVSKKLGNAVTRNQIKRRIRHIIQNAKGSLVEDVDFVVIARKGVETLGYAEMEKNLLH
                     VLKLSKIYREGNGSEKETKVD"
     gene            5225..6049
                     /locus_tag="VQ862_001242"
     CDS             5225..6049
                     /locus_tag="VQ862_001242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000727905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HET3115597.1"
                     /translation="MKKKLKLTSLLGLSLLIMTACATNGVTSDITAESADFWSKLVYF
                     FAEIIRFLSFDISIGVGIILFTVLIRTVLLPVFQVQMVASRKMQEAQPRIKALREQYP
                     GRDMESRTKLEQEMRKVFKEMGVRQSDSLWPILIQMPVILALFQALSRVDFLKTGHFL
                     WINLGSVDTTLVLPILAAVFTFLSTWLSNKALSERNGATTAMMYGIPVLIFIFAVYAP
                     GGVALYWTVSNAYQVLQTYFLNNPFKIIAEREAVVQAQKDLENRKRKAKKKAQKTK"
     gene            6068..7054
                     /locus_tag="VQ862_001243"
     CDS             6068..7054
                     /locus_tag="VQ862_001243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein jag"
                     /protein_id="HET3115598.1"
                     /translation="MVVFTGSTVEEAIQKGLKELDIPRMKAHIKVISREKKGFLGLFG
                     KKPAQVDIEAISETTVVKANQQVVKGVPKKINDLNEPVKTVSEETVDLGHVVDAIKKI
                     EEEGQGISDEVKAEILKHERHASTILEETGHIEILNELQIEEAMREEAGADDLETEQD
                     QTENQDLKEMGLKVEQSYDIAQVATDVTAYVQAIVDDMDVEATLSNDYNRRSINLQID
                     TNEPGRIIGYHGKVLKALQLLAQNYLYNRYSRTFYVTINVNDYVEHRAEVLQTYAQKL
                     ATRVLEEGRSHKTDPMSNSERKIIHRIISRMDGVTSYSEGDEPNRYVVVDTE"
     gene            7105..7728
                     /locus_tag="VQ862_001244"
     CDS             7105..7728
                     /locus_tag="VQ862_001244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000932659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P"
                     /protein_id="HET3115599.1"
                     /translation="MLNKIRDYLDFAGLQYRNPDKAGAEREKMLAFRHKGQEARKAFT
                     ELAKAFQASHPEWQLQQTSQWMNQAQRLRPHFWVYLQRDGQVTEPMMALRLYGTSTDF
                     GISLEVSFIERKKDEQTLGKQAKVLDIPTVKGIYYLTYSNGQSQRWEANEEKRRTLRE
                     KVRSQEVRKVLVKVDVPMTENSSEEEIVEGLLKSYSKILPYYLATRK"
     gene            7859..9316
                     /locus_tag="VQ862_001245"
     CDS             7859..9316
                     /locus_tag="VQ862_001245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HET3115600.1"
                     /translation="MEVVSSVLNWFSSNILQNPAFFVGLLVLIGYALLKKPAHDVFSG
                     FVKATVGYMLLNVGAGGLVTTFRPILAALNYKFQIGAAVIDPYFGLAAANNKIAAEFP
                     DFVGTATTALLIGFGINILLVALRKITKVRTLFITGHIMVQQAATVSLMVLFLVPQLR
                     NAYGTAAIGIICGLYWAVSSNMTVEATQRLTGGGGFAIGHQQQFAIWFVDKVAGRFGK
                     KEESLDNLKLPKFLSIFHDTVVASATLMLVFFGAILLILGPDIMSNKEVITSGTLFNP
                     AKQDFFMYIIQTAFTFSVYLFVLMQGVRMFVSELTNAFQGISNKLLPGSFPAVDVAAS
                     YGFGSPNAVLSGFTFGLIGQLITIVLLIVFKNPILIITGFVPVFFDNAAIAVYADKRG
                     GWKAAVILSFISGVLQVALGALCVALLDLASYGGYHGNIDFEFPWLGFGYIFKYLGIV
                     GYVLVCLFLLVIPQLQFAKAKDKEKYYNGEVQEEA"
     gene            9339..9620
                     /locus_tag="VQ862_001246"
     CDS             9339..9620
                     /locus_tag="VQ862_001246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HET3115601.1"
                     /translation="MVKVLAACGNGMGSSMVIKMKVENALRKLNQTDFTVNSCSVGEA
                     KGLAVGYDIVIASLHLIQELEGRTNGKLIGLDNLMDDKEITEKLSQALQ"
     gene            9697..10182
                     /locus_tag="VQ862_001247"
     CDS             9697..10182
                     /locus_tag="VQ862_001247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HET3115602.1"
                     /translation="MNLKQALIDNDSIRLGLEANNWKEAVKVAVDPLIESGAILPEYY
                     DAIIESTEEYGPYYILMPGMAMPHARPEAGVQSDAFSLITLQNPVVFSDGKEVSVLLA
                     LAATSSKIHTSVAIPQIIALFELEDSIARLQACQTKEDVLAMIEESKDSPYLEGLDLE
                     S"
     gene            10199..10864
                     /locus_tag="VQ862_001248"
     CDS             10199..10864
                     /locus_tag="VQ862_001248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-keto-L-gulonate-6-phosphate decarboxylase
                     UlaD"
                     /protein_id="HET3115603.1"
                     /translation="MTKRIPNLQVALDHSDLQGAIKAAVSVGQEVDIIEAGTVCLLQV
                     GSELAEVLRSLFPDKIIVADTKCADAGGTVAKNNAVRGADWMTCICCATIPTMEAALK
                     AIKTERGERGEIQIELYGDWTFEQAQLWLDAGISQAIYHQSRDALLAGETWGEKDLNK
                     VKKLIDMGFRVSVTGGLDVDTLKLFEGVDVFTFIAGRGITEAADPAGAARAFKDEIKR
                     IWG"
     gene            10868..11731
                     /locus_tag="VQ862_001249"
     CDS             10868..11731
                     /locus_tag="VQ862_001249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000252119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 3-epimerase"
                     /protein_id="HET3115604.1"
                     /translation="MVRPIGIYEKATPTHFTWLERLNFAKELGFDFVEMSIDERDERL
                     ARLDWSKEERLEVVKAIYETGVRIPSICFSGHRRYPLGSKDPVLEEKSLELMKKCIEL
                     AQDLGVRTIQLAGYDVYYEEKSPQTRQRFIKNLRKACDWAEEAQVVLAIEIMDDPFIS
                     SIEKYLAIEKEIDSPFLFVYPDIGNVSAWHNDIYSEFYLGHHAIAALHLKDTYAVTES
                     SKGQFRDVPFGQGCVKWEEAFDILKETNYNGPFLIEMWSENCETVEETRAAVQEAQAF
                     LYPLIKKAGLM"
     gene            11733..12437
                     /locus_tag="VQ862_001250"
     CDS             11733..12437
                     /locus_tag="VQ862_001250"
                     /EC_number="5.1.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001077552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HET3115605.1"
                     /translation="MNQVINAMRKRVCDANQSLPKHGLVKFTWGNVSEVNRELGVIVI
                     KPSGVDYDELTPENMVVTDLDGKILEGDLRPSSDLPTHVQLYKAWSEIGSVVHTHSTE
                     AVGWAQAGRDIPFYGTTHADYFYGSIPCARSLTKDEVEVAYEKDTGLVIVEEFEHRGL
                     NPVEVPGIVVRNHGPFTWGKNPENAVYHSVVLEEVSKMNRFTEQINPRVGPAPQYILE
                     KHYQRKHGPNAYYGQK"
     gene            12616..14289
                     /locus_tag="VQ862_001251"
     CDS             12616..14289
                     /locus_tag="VQ862_001251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HET3115606.1"
                     /translation="MVLDKASCDLLQYLMDQETSKTIMAISKDLKESRRKIYYHIDKI
                     NAALGDEALHIISIPRIGIHLTEEQRDACCKLLSEVDSYDYIMSAHERMMIMLLWIGI
                     SKERITIEKLIELTEVSRNTVLNDLNSIRYQLTLEQYQVILQVSKSQGYHLHAHPLNK
                     IQYLQSLLYHIFMEENATFVSILEDKMKERLDDECLLSVEMNQFFKEQVPLVEQDLGK
                     KINHHEITFMLQVLPYLLLSCHNVEQYQERHQDIEKEFSLIRKRIEYQVSKKLGERLF
                     QKFEISLSGLEVSLVAVLLLSYRKDLDIHAESDDFRQLKLALEEFIWYFESQIRMEIE
                     NKDDLLRNLMIHCKALLFRKTYGIFSKNPLTKQIRSKYGELFLVTRKSAEILEGAWFI
                     RLTDDDIVYLTIHIGGFLKYTPSSQKNMKKVYLVCDEGVAVSRLLLKQCKLYFPNEQI
                     DTVFTTEQFKSVEDIAQVDVVITTNDDLDSRFPILRVNPILEAEDILKMLDYLKHNIF
                     RNKSKSFSENLSSLISSYIVDSKLASKFQEEVQTLINQEIVVQAFLEDI"
     gene            14401..15492
                     /gene="ulaG"
                     /locus_tag="VQ862_001252"
     CDS             14401..15492
                     /gene="ulaG"
                     /locus_tag="VQ862_001252"
                     /EC_number="3.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ascorbate 6-phosphate lactonase"
                     /protein_id="HET3115607.1"
                     /translation="MPNVKEITRESWILATFPEWGTWLNEEIEEEVVPEGNFAMWWLG
                     NCGTWIKTPAGANVVMDLWSNRGKSTKKVKDMVRGHQMANMAGVRKLQPNLRVQPMVI
                     DPFAINELDYYLVSHFHSDHIDPYTAAAILNNPKLEHVKFIGPYHCGRIWEGWGVPKE
                     RIIVVKPGDTIELKDMKIHAVESFDRTCLVTLPVNGADETGGELAGLAVTDEEMAQKA
                     VNYIFETPGGTIYHGADSHFSNYFAKHGKDFKIDVALNNYGENPVGIQDKMTSIDLLR
                     MAENLRTKVIIPVHYDIWSNFMASTNEILELWKMRKDRLQYDFHPFIWEVGGKYTYPQ
                     DQHLVEYHHPRGFDDCFEQDSNIQFKALL"
     gene            15606..17582
                     /gene="tkt"
                     /locus_tag="VQ862_001253"
     CDS             15606..17582
                     /gene="tkt"
                     /locus_tag="VQ862_001253"
                     /EC_number="2.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004185329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HET3115608.1"
                     /translation="MSNLSVNAIRFLGIDAINKANSGHPGVVMGAAPMAYSLFTKQLH
                     INPAQPNWINRDRFILSAGHGSMLLYALLHLSGFEDVSMDEIKSFRQWGSKTPGHPEF
                     GHTAGIDATTGPLGQGISTATGFAQAERFLAAKYNREGYNIFDHYTYVICGDGDLMEG
                     VSSEAASYAGLQKLDKLVVLYDSNDINLDGETKDSFTESVRDRYNAYGWHTALVENGT
                     DLEAIHAAIETAKASGKPSLIEVKTVIGYGSPNKQGTNAVHGAPLGADETASTRQALG
                     WDYEPFEIPEQVYADFKEHVADRGASAYQAWTKLVADYKEAHPELAAEVEAIIDGRDP
                     VEVTPADFPALENGFSQATRNSSQDALNVVAAKLPTFLGGSADLAHSNMTYIKTDGLQ
                     DDTNRLNRNIQFGVREFAMGTILNGMALHGGLRVYGGTFFVFSDYVKAAVRLSALQGL
                     PVTYVFTHDSIAVGEDGPTHEPVEHLAGLRAMPNLNVFRPADARETQAAWYLAVTSEK
                     TPTALVLTRQNLTVEDGTDFDKVAKGAYVVYENAADFDTILIATGSEVNLAVSAAKEL
                     ASQGEKIRVVSMPSTDVFDKQDAAYKEEILPNAVRRRVAVEMGASQNWYKYVGLDGAV
                     LGIDTFGASAPAPKVLAEYGFTVENLVKVVRNLK"
     gene            17699..17998
                     /gene="yajC"
                     /locus_tag="VQ862_001254"
     CDS             17699..17998
                     /gene="yajC"
                     /locus_tag="VQ862_001254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001069053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HET3115609.1"
                     /translation="MNPNITFLIMLVGMMALMFFMQRSQKKQAQKRMESLNKLQKGYE
                     VITIGGLYGTVDEVDTEKGTIVLDVDGVYLTFELAAIKTVLPLKETASLEGAIEK"
     gene            18044..18472
                     /locus_tag="VQ862_001255"
     CDS             18044..18472
                     /locus_tag="VQ862_001255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000737444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="low molecular weight phosphotyrosine protein
                     phosphatase"
                     /protein_id="HET3115610.1"
                     /translation="MKKLVFVCLGNICRSPMAEFVMKSMTDNYEIQSRATSSWEHGNP
                     IHKGTQGIFQEYEIPYDKNKTSLQISKEDFEAFDYIIGMDASNISDLRQMCPVDCQDK
                     IYSFSSESVPDPWYTGDFEETYRRVQEGCQAWLERLEKES"
     gene            18474..18884
                     /locus_tag="VQ862_001256"
     CDS             18474..18884
                     /locus_tag="VQ862_001256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000427064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3115611.1"
                     /translation="MENLTNFYEKYRVYLTRPRLELLAVVTIVFCAVLVFFLNIPGKG
                     VLKLDNGTIVYDGSLVRGKMNGQGTITFQNGDQYTGGFNNGAFNGKGTFQSKEGWTYE
                     GDFVNGQAEGKGKLTTEQEVVYEGTFKQGVFQQK"
     gene            19183..21834
                     /gene="adhE"
                     /locus_tag="VQ862_001257"
                     /gene_synonym="adhC"
     CDS             19183..21834
                     /gene="adhE"
                     /locus_tag="VQ862_001257"
                     /gene_synonym="adhC"
                     /EC_number="1.1.1.1"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000763984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acetaldehyde-CoA/alcohol
                     dehydrogenase"
                     /protein_id="HET3115612.1"
                     /translation="MADKKTVTPEEKKLVAEKHVDELVQKALVALEEMRKLDQEQVDY
                     IVAKASVAALDAHGELALHAFEETGRGVFEDKATKNLFACEHVVNNMRHTKTVGVIEE
                     DDVTGLTLIAEPVGVVCGITPTTNPTSTAIFKSLISLKTRNPIVFAFHPSAQESSAHA
                     ARIVRDAAIAAGAPENCVQWITQPSMEATSALMNHEGIATILATGGNAMVKAAYSCGK
                     PALGVGAGNVPAYVEKSANIRQAAHDIVMSKSFDNGMVCASEQAVIIDKEIYDEFVAE
                     FKSYHTYFVNKKEKALLEEFCFGVKANSKNCAGAKLNADIVGKPATWIAEQAGFTVPE
                     GTNILAAECKEVGENEPLTREKLSPVIAVLKSESREDGITKARQMVEFNGLGHSAAIH
                     TADEELTKEFGKAVKAIRVICNSPSTFGGIGDVYNAFLPSLTLGCGSYGRNSVGDNVS
                     AINLLNIKKVGRRRNNMQWMKLPSKTYFERDSIQYLQKCRDVERVMIVTDHAMVELGF
                     LDRIIEQLDLRRNKVVYQIFADVEPDPDITTVNRGTEIMRAFKPDTIIALGGGSPMDA
                     AKVMWLFYEQPEVDFRDLVQKFMDIRKRAFKFPLLGKKTKFIAIPTTSGTGSEVTPFA
                     VISDKANNRKYPIADYSLTPTVAIVDPALVLTVPGFVAADTGMDVLTHATEAYVSQMA
                     SDYTDGLALQAIKLVFENLESSVKNADFHSREKMHNASTIAGMAFANAFLGISHSMAH
                     KIGAQFHTIHGRTNAILLPYVIRYNGTRPAKTATWPKYNYYRADEKYQDIARMLGLPA
                     STPEEGVESYAKAVYELGERIGIQMNFRDQGIDEKEWKEHSRELAFLAYEDQCSPANP
                     RLPMVDHMQEIIEDAYYGYKERPGRRK"
BASE COUNT         6951 a         3980 c         4833 g         6356 t
ORIGIN      
        1 atgttggtgg tcttgctgat tatcagcgtg cttttcttgc tctttgtacc taatctgacc
       61 aagcaaaaag aagcagtcaa tgacaaagga aaagcagctg ttgttaaggt ggtggaaagc
      121 caggcagaac tttatagctt ggaaaagaat gaagatgcta gcctaagcaa gttaaaagac
      181 gatgggcgaa tcacggaaga acaggttaaa gcttataaag aatacaatga taaaaatgta
      241 ggagcaaatc gtaaagtcaa tgattaaggc ctttaccatg ctggaaagtc tcttggtttt
      301 gggtcttgtg agtatccttg ccttgggctt gtccggctct gttcagtcca cttttgcggc
      361 agtagaggaa cagattttct ttatggaatt tgaagaactc tatcgggaaa cccaaaaacg
      421 cagtgtagcc agtcagcaaa agactagtct gaacttagat gggcagacga ttagcaatgg
      481 cagtcaaaag ttgccagtcc ctaaaggaat tcaggtccca tcaggccaaa gtattacatt
      541 tgaccgtgct gggggcaatt cgtccctggc taaggttgaa tttcagacca gtaaaggagc
      601 gattcgctat caattatatc taggaaatgg aaaaattaaa cgcattaagg aaacaaaaaa
      661 ttagggcagt gattttactg gaagcagtag tcgctctagc tatctttgcc agcattgcga
      721 ccctcctttt gggacaaatt caaaaaaata ggcaagagga agcaaaaatc ttgcaaaagg
      781 aagaagtctt gagggtagct aagatggcct tgcagacggg gcaaaatcag gtaagcatca
      841 acggagttga gattcaggta ttttctagtg aaaaaggatt ggaggtctac catggttcag
      901 aacagttgtt ggcaatcaaa gagccataag gtcaaggctt ttaccttgtt agaatccctg
      961 cttgccctca ttgtcatcag tgggggatta ctcctttttc aagctatgag tcagctcctc
     1021 atttcagaag ttcgctacca gcaacaaagc gagcaaaagg agtggctctt gtttgtggac
     1081 caacttgagg tagaattaga ccgttcgcag ttcgaaaaag tagaaggcaa tcgcctatac
     1141 atgaagcaag atggcaagga catcgccatc ggtaagtcaa agtcagacga ttttcgtaaa
     1201 accgatgcta gtggacgggg gtatcagcct atggtttatg gcctcaaatc agctcagatt
     1261 acagaggaca atcaactggt tcattttcgt ttccagtttc aaaaaggctt agaaagggag
     1321 ttcatctatc gtgtggaaaa agaagaaagt taaggcaggt gttctcctct atgcagtcac
     1381 catggcagct atctttagtc ttttgttgca attttacttg aaccgacaag tcgcccacta
     1441 tcaagactat gctttgaata aagaaaaatt ggttgctttt gccatggcta aacgaaccaa
     1501 ggataaagcc gagcaagaaa gtggggaaca ggtctttaat ctaggtcagg taagctatca
     1561 aaacaagaaa acaagcttgg tgacgactgt tcgtacgtct aagagccaat atgagtttct
     1621 gtttccttca gtcaaaatca aagaagagaa aagagataaa aaggaagagg tagcgaccga
     1681 ttcaagcgaa aaagtggaga agaaaaaatc agaagagaag cctgaaaaga aagagaattc
     1741 ctagtcaatt caactataat gcgttgaatc aagaatagtc cactatagtt tctagaaaat
     1801 tgctggaaat ggatgttaag ctccaattca tttgtttata tcttatttca gtttactata
     1861 ctttgtgcta aattaaagat atgaaacatg attttaacca caaagcagaa actttcgatt
     1921 cccctaaaaa tatcttcctc gcaaacttgg tatgtcaagc agccgagaaa cagattgatc
     1981 ttctatcaga caaagaaatt ttagatttcg gtggtgacac gggtctatta gccttgcccc
     2041 tagcccctag ccaagcaggc taagtcagtc actcttgtag acatttctga gaaaatgttg
     2101 gagcaagctc gtttgaaagt ggagcagcaa gcaatcaaga atatccagtt tttggagcaa
     2161 gatttaccga aaaatccctt ggagaaagag tttgattgcc ttgctgttag tcgggttctt
     2221 catcatatgc ctgatttgga tgcggctctc tcactgtttc atcaacattt gaagtaagat
     2281 gggaaactca tcattgctga ttttaccaag acagaagcta atcatcatgg atttgattta
     2341 gctgaactgg aaaacaagct aattgagcat ggtttttcat ctgtgcatag tcagattctc
     2401 tatagcgctg aagacttgtt tcaaggaaat cactcagaat tctttttaat agtagcccaa
     2461 aaatcactcg cctagtcagg gagtgatttt tctataagga tggaaaaaag aagggaaatt
     2521 tgataagata ggaatatgga ttttgaaaaa attgaacaag cttataccta tttactagag
     2581 aatgtccaag tcatccaaag tgatttggcg accaactttt atgacgcctt ggtggagcaa
     2641 aacagcatct atctggatgg tgaaactgag ctaaaccagg tcaaagacaa caatcaggcc
     2701 cttaagcatt tagcactacg caaagaagaa tggctcaaga cctaccagtt tctcttgatg
     2761 aaggctgggc aaacagaacc cttgcaggcc aatcaccagt ttacaccgga tgctattgct
     2821 ttacttttgg tgtttattgt ggaagagctg tttaaagagg aggaaattac tatcctcgaa
     2881 atgggttctg ggatgggaat tttgggcgct actttcttga cctcgcttac taaaaaggtg
     2941 gattatttgg gaatggaagt ggatgatttg ctgattgatt tggcagctag catggcagat
     3001 gtaattggtt tgcaggctgg ctttgtccaa ggagatgccg ttcgtccaca aatgctcaaa
     3061 gaaagtgatg tggtcatcag cgacttgcct gttggctatt atcctgatga tgccgttgcg
     3121 tcgcgccatc aagttgcttc tagtcaagaa catacttacg cccatcactt gctcatggaa
     3181 caaggactta agtacctcaa gtcagacgga tacgctattt ttctagctcc gagtgatttg
     3241 ttgaccagtc ctcaaagtaa tttgttgaaa gtctggttga aagaggaggc aagtctggtt
     3301 gctatgatta gtttacctga aaatctcttt gctaatgcta aacaatctaa gactattttt
     3361 atcctacaga agaaaagtga aatagcagta gagccttttg tttatccact tgctagcttg
     3421 caagatgcaa gtgttttaat gaaatttaaa gaaaattttc aaaaatggac tcaaggtact
     3481 gaaatataaa atagattttg ttataatagt tgaaaacgct taaaaagggg tatcatgtta
     3541 tgacaaaaac aattgcaatc aatgcaggaa gttcaagttt gaaatggcaa ttatacttaa
     3601 tgccagaaga aaaagtattg gcgaaaggtt tgattgaacg tatcggtttg aaagattcaa
     3661 tttcaactgt aaaatttgac ggccgttctg aacaacaaat tttggatatt gaaaatcata
     3721 cacaagctgt taaaatttta ttggatgact tgattcgttt cgatattatc aaggcttatg
     3781 acgagattac aggtgttgga catcgtgttg ttgctggtgg agaatatttc aaagaatcaa
     3841 cagttgttga gggagatgtt ttagaaaaag ttgaagagtt gagtttgttg gctcctctac
     3901 acaacccggc aaatgcagca ggtgttcgtg ccttcaagga attgttgcca gacattacca
     3961 gtgtagttgt ttttgatact tccttccaca caagtatgcc agagaaagct tatcgctacc
     4021 ctctaccaac aaaatattac acagaaaaca aggttcgtaa atacggtgct catggtacaa
     4081 gtcaccagtt tgtagcagga gaagctgcaa aactcttggg acgtccatta gaagacttga
     4141 agttaattac ctgtcatatt ggtaacggag gctcaattac agctgtgaaa gccggcaaat
     4201 ctgtagacac ttctatgggg ttcactcctc ttggtggtat tatgatggga acgcgtacag
     4261 gggatattga tccagctatc attccttatt taatgcaata tacagaggat tttaacacac
     4321 cagaagatat cagtcgtgtt cttaaccgtg aatcaggtct tttgggagtt tctgctaatt
     4381 ctagcgatat gcgcgatata gaagcagctg tagcagaagg gaatcacgag gctagcttgg
     4441 cttatgaaat gtatgttgac cgtatccaaa aacatatcgg tcagtacctt gcagtgctaa
     4501 atggagcaga tgccattgtt ttcacagcag gtgtcggtga aaatgcagag agtttccgtc
     4561 gtgatgtaat ctcagggatt tcgtggtttg gttgtgatgt tgatgatgaa aagaatgtct
     4621 ttggcgttac aggagacatc tcaacagagg cagctaaaat ccgtgtcttg gttattccaa
     4681 cagatgaaga attagtcatt gcccgtgacg ttgaacgctt gaaaaaataa gtgaaactaa
     4741 aaaaatattc aatacaagga gttgggaaag ttatttttcc agcttctttt tctgatgaaa
     4801 ttgtccaaaa ccttgctatg attggctttt ttgaaaaata tggtataata gtagtaattt
     4861 aatagatgga gttgagtttt gaagaaaaac tttcgtgtaa aaagagagaa agattttaag
     4921 gcgattttca aggaggggac aagttttgct aatcgcaaat ttgtggtcta ccaattagaa
     4981 aaccagaaaa accattttcg agtaggtcta tcagttagca aaaaactggg gaatgccgtc
     5041 actagaaatc aaattaagcg acggattcgg catattatcc agaatgcaaa agggagtctg
     5101 gtagaagatg tcgactttgt tgtcattgct cgaaaaggag tcgaaacctt gggatacgca
     5161 gagatggaga aaaatctact ccatgtatta aaattatcaa agatttaccg ggaaggaaat
     5221 gggagtgaaa aagaaactaa agttgactag tttgctagga ctgtctctgt taatcatgac
     5281 agcctgtgcg actaatgggg taactagcga tattacagcc gaatcggctg atttttggag
     5341 taaattggtt tacttctttg cggaaatcat tcgcttttta tcgtttgata ttagtatcgg
     5401 agtggggatt attctcttta cggtcttgat tcgtacagtc ctcttgccag tctttcaggt
     5461 gcaaatggtg gcttctagga aaatgcagga agctcagcca cgcattaagg cgcttcgaga
     5521 acaatatcca ggtcgagata tggaaagcag aaccaaacta gagcaggaaa tgcgtaaagt
     5581 atttaaagaa atgggtgtca gacagtcaga ctctctttgg ccgattttga ttcagatgcc
     5641 ggttattttg gccctgttcc aagccctatc aagagttgac tttttaaaga caggtcattt
     5701 cttatggatt aaccttggta gtgtggatac aacccttgtt cttccgattt tagcagcagt
     5761 attcaccttt ttaagtactt ggttgtccaa caaagctttg tctgagcgaa atggcgctac
     5821 gactgcgatg atgtatggga ttccagtctt gatttttatc tttgcagttt atgcgccagg
     5881 tggagtcgcc ctatactgga cagtgtctaa tgcttatcaa gtcttgcaaa cctatttctt
     5941 gaataatcca ttcaagatta tcgcagagcg cgaggccgta gtacaggcac aaaaagattt
     6001 ggaaaataga aaaagaaaag ccaagaaaaa ggctcagaaa acgaaataaa taaggaggaa
     6061 tctggtaatg gtagtattta caggttcaac tgttgaagaa gcaatccaga aaggattgaa
     6121 agaattagat attccaagaa tgaaggctca tatcaaagtc atttctaggg agaaaaaagg
     6181 ctttcttggt ctatttggta aaaaaccagc ccaagtggat attgaagcga ttagtgaaac
     6241 gactgttgtc aaagcaaatc aacaggtagt aaaaggcgtt ccgaaaaaaa tcaatgattt
     6301 gaacgagcct gtgaagacgg ttagtgaaga aaccgttgac cttggtcatg tggttgatgc
     6361 tattaaaaaa atagaggaag aaggtcaagg tatttctgat gaagtcaagg ctgaaatctt
     6421 aaaacatgaa agacatgcca gcactatctt agaagaaact ggtcacattg agattttaaa
     6481 tgaacttcaa atcgaggaag cgatgaggga agaagcaggc gctgatgacc ttgaaactga
     6541 gcaagatcaa actgaaaatc aagacttgaa agagatgggc ttgaaggtcg agcaaagtta
     6601 tgatattgcc caggtggcta cggatgtgac tgcctatgtt caagcgattg tggatgacat
     6661 ggatgttgaa gctacacttt caaatgatta taaccgtcgt agcatcaatc tacaaattga
     6721 caccaacgaa ccaggtcgta ttatcggcta ccatggtaaa gtcttgaagg ccttgcaact
     6781 gttggctcaa aattatcttt acaaccgcta ttccagaacc ttctacgtta caatcaatgt
     6841 caatgattat gtcgaacacc gtgcagaagt cttgcagacc tatgcgcaaa aattggcgac
     6901 tcgtgttttg gaagaagggc gcagtcataa aacagatcca atgtcaaata gcgaacgcaa
     6961 gattatccat cgtattattt cacgtatgga tggcgtgact agttactctg aaggtgatga
     7021 gccaaatcgc tatgttgttg tagatacaga ataagtaaaa tcaggtttat cctgattttt
     7081 tgctagttag aggaggttaa actgatgttg aataagataa gagactattt agactttgct
     7141 ggtttgcagt accgtaatcc tgataaagcg ggagcagagc gagagaagat gctggcattc
     7201 cgccacaaag gacaagaggc ccgaaaggct tttacagaac tggccaaagc ctttcaagca
     7261 agccatccag aatggcaact ccaacagact agccagtgga tgaatcaggc ccagcgtttg
     7321 agaccacatt tttgggttta tctacagaga gacggacaag tgacagaacc tatgatggcc
     7381 ttacgtttgt atgggacatc tactgacttt ggaatttctt tggaagtcag tttcatcgaa
     7441 cgtaagaagg atgagcaaac actgggcaag caggccaaag ttttagacat tccaaccgtt
     7501 aaagggattt attatctaac ctactctaat ggtcaaagtc aacggtggga ggcgaatgaa
     7561 gaaaagcgtc gtactttacg cgagaaggtg agaagtcaag aagttcgaaa agttttagtg
     7621 aaggtagatg ttcctatgac agaaaattcg tctgaagaag aaatcgtaga aggcttattg
     7681 aagtcttatt ctaaaattct tccctattat ctagctacga gaaaataaga taatttgtaa
     7741 aacatcataa atcatacagt ccaagagtga acagtccgct gtgtaattct tggtcttttt
     7801 gtttgcgctt tcgcattata taataaactt acaaaaacaa ttcaaaagga gaacaattat
     7861 ggaagtcgtt tcaagtgttc taaattggtt ttctagcaat attttgcaga atcccgcatt
     7921 tttcgtaggt ttattggtgt tgataggata tgcacttttg aaaaaacctg cccatgacgt
     7981 tttttcaggg tttgttaaag caacagtagg gtatatgttg cttaacgtgg gtgctggtgg
     8041 tttggttaca acctttcgtc caatcttagc agctcttaac tacaaattcc aaattggtgc
     8101 agcggttatc gacccttact ttggacttgc tgcagcaaac aacaaaattg cagcagagtt
     8161 tccagatttt gttggaactg caactacagc tctattgatt ggttttggaa taaatatctt
     8221 gctcgtagct cttcgaaaga ttacgaaggt aagaaccctc tttattactg gtcacatcat
     8281 ggtacaacaa gctgcaacag tatctcttat ggttctattc ttagtaccac aattgcgcaa
     8341 tgcttacggt acagcagcga ttggtatcat ctgtggactt tactgggcag ttagttcaaa
     8401 tatgactgtt gaggcaactc aacgcttgac tggtggtggc ggatttgcga ttggtcacca
     8461 acagcaattt gcaatctggt ttgtagataa agtagcagga cgctttggta agaaagaaga
     8521 aagtttagac aatcttaaat tacctaagtt cctctcaatc ttccacgata cagttgttgc
     8581 atctgctacc ttgatgctcg tattcttcgg agccattctt ttaatcttgg gtccagacat
     8641 tatgtctaat aaagaagtca tcacttcagg aactctattc aatcctgcta aacaagattt
     8701 ctttatgtac attatccaaa cagcctttac cttctcagtt tacttgttcg ttttgatgca
     8761 aggtgtccga atgttcgtat ctgagttgac aaacgccttc caaggtattt caaacaaatt
     8821 gttgccaggt tcattcccag cggttgacgt tgcagcttct tatggatttg gttctccaaa
     8881 tgctgtcttg tcaggattta cctttggttt gattggtcaa ttgattacaa ttgtcttgct
     8941 catcgtcttt aaaaatccga ttcttattat tacaggattt gtaccagtgt tctttgacaa
     9001 tgcagccatt gcggtctacg ctgataaacg cggcggatgg aaagcggctg ttatcctttc
     9061 ctttatatca ggtgtccttc aagttgctct aggagctctt tgtgtggccc ttctcgattt
     9121 ggcatcttat ggtggctacc atggaaatat cgactttgaa ttcccatggc ttggatttgg
     9181 atatatcttc aaataccttg gtattgttgg ttatgtactt gtgtgtctct tcttgcttgt
     9241 tattcctcaa cttcaatttg ccaaagcaaa agataaagag aaatattaca acggtgaagt
     9301 tcaagaagaa gcttagtatc tagaaaagga gaaataaaat ggttaaagta ttagcagcgt
     9361 gcggaaatgg aatgggttca tcaatggtta tcaagatgaa ggttgaaaat gctctccgta
     9421 agcttaatca aacagatttt acagtcaatt catgcagtgt cggtgaagct aaaggtttag
     9481 cagtaggata tgacatcgta atcgcttctc ttcatttgat tcaagaattg gaagggcgaa
     9541 ctaatgggaa gttaattggt cttgataact tgatggatga taaagaaatc accgaaaaac
     9601 tcagtcaagc actacagtaa aaggttggag ggggctggac agaaactgag agttatcgtt
     9661 tctgtccttc tccctcttta aataaaggag gcagatatga atttaaaaca agctttaatt
     9721 gacaatgact cgatccgact aggtttagag gctaacaatt ggaaagaagc agtcaaggta
     9781 gcagtagatc ccctaattga aagtggggca attttgccag agtattacga tgctatcatt
     9841 gaatcgactg aagagtatgg gccttactat atcttgatgc caggtatggc tatgccccac
     9901 gctagacctg aagctggtgt gcaaagtgat gccttttcat tgattacctt acaaaatcct
     9961 gttgtatttt cagatgggaa agaggtatct gttttgttgg cactagcagc aacaagttca
    10021 aaaattcaca caagtgtagc cattccacaa attattgccc tgtttgaatt agaagattct
    10081 attgcacgtt tacaggcttg ccagactaaa gaagatgtct tggctatgat tgaagaatct
    10141 aaggatagcc cttatctcga aggattggat ttggaaagtt agaaagagga ataaagaaat
    10201 gacaaaaaga atacctaatt tacaagttgc attagaccat tcagacttgc aaggagcgat
    10261 taaagcagct gtttctgttg gtcaggaagt agatattatc gaagctggaa ctgtttgctt
    10321 gcttcaagtt ggaagtgaac tggctgaagt cttgcgtagc cttttcccag ataagattat
    10381 tgtggcagac acaaaatgtg ctgatgctgg tggaacagtt gctaaaaata atgcggttcg
    10441 tggagcagac tggatgactt gtatctgttg tgcaaccatc cctactatgg aagcagctct
    10501 aaaggctatc aagactgaac gaggagaacg aggcgaaatc cagatcgagc tttatggcga
    10561 ttggactttt gaacaagctc agctttggct agatgcaggt atctcacaag ctatttatca
    10621 ccaatctcgt gatgctcttc ttgctggtga aacttggggt gaaaaagacc ttaataaggt
    10681 taaaaaactc attgacatgg gcttccgtgt atctgtaaca ggtggtctag atgtagatac
    10741 tctcaaactc tttgaaggtg ttgatgtctt tacctttatc gcaggtcgtg gaattacaga
    10801 ggctgcggat ccagcaggag cagcgcgtgc cttcaaggat gaaatcaaac gaatttgggg
    10861 gtaaatcatg gtacgtccaa ttggaattta tgaaaaggca accccaacac actttacttg
    10921 gctagaacgt ttaaattttg ccaaggagtt aggctttgat tttgtcgaga tgtctattga
    10981 cgaacgtgac gagcgtttag caagacttga ctggagtaag gaagaacgct tggaagttgt
    11041 caaagcaatc tatgaaactg gtgttcgtat tccttctatc tgtttttcag gccatcgtcg
    11101 ctacccattg ggttcaaaag atccagttct agaggaaaaa tctctagaac tcatgaaaaa
    11161 atgtatcgaa ttagctcaag acttgggagt tcgtacgatt caattagctg gttacgatgt
    11221 ttactatgag gaaaagtcac cccagacacg ccaacgtttt atcaaaaatt tgagaaaagc
    11281 ctgtgactgg gctgaagaag ctcaggtggt acttgctatt gaaattatgg atgatccttt
    11341 catcagtagc atcgaaaaat atttggctat agaaaaagag attgactctc ccttcctctt
    11401 tgtatatcca gatattggta atgtgtctgc atggcataat gatatctata gtgagtttta
    11461 tcttggtcat catgccatcg cagctctcca tctcaaggat acttatgcag tgacagaaag
    11521 ttcaaagggc cagttccgag atgtaccttt cgggcaaggt tgtgtcaaat gggaagaagc
    11581 tttcgatatt ttaaaggaaa ccaattataa tggacctttc ctaatcgaaa tgtggtctga
    11641 aaattgtgaa acagtagaag aaacacgcgc agccgttcaa gaggcgcaag cttttctcta
    11701 tccactcatt aagaaagcag gtttgatgta agatgaatca agtaatcaat gctatgcgta
    11761 aacgagtctg tgatgccaat caatcattgc caaaacatgg acttgtcaaa tttacctggg
    11821 ggaatgtatc tgaagttaat cgcgaactcg gtgtcattgt tatcaaacca tcaggcgtgg
    11881 attatgacga attgacacct gaaaacatgg tagtgactga tctagatggt aagatcctag
    11941 aaggggattt aagaccatct tccgacctcc caactcatgt gcaattatat aaggcttggt
    12001 cagaaattgg tagtgtggtt cacacccatt cgacagaagc tgttggttgg gctcaggcag
    12061 gtcgtgatat tcctttctac ggaacaaccc atgcagatta tttctacggt tcaatccctt
    12121 gcgcccgtag tttgaccaag gacgaagtag aagtggccta tgaaaaagat actggcctgg
    12181 ttatcgtaga agagtttgaa catcgcggac ttaacccggt tgaagtacca ggaattgttg
    12241 tacgcaatca cggtccattc acctggggca aaaatccaga gaatgctgtt tatcactctg
    12301 tcgtactaga ggaagtatca aagatgaatc gctttacaga acaaatcaat ccaagagttg
    12361 gacctgctcc ccagtacata ctagaaaaac actaccaacg taaacatgga ccaaatgctt
    12421 attatggtca aaagtaagaa cgatgaagga ggagaaaaag ataaatttag ctcctctttt
    12481 tacatttgat ttttattgag agtaaagttg gaattgaagt aattttaaaa gattttttag
    12541 aaatagcgct tgatatatat atggtaaaat aaaaagaatt gctgtgatat caatagattt
    12601 gggggatttt ttaatatggt actggataag gcaagttgtg atttgcttca atatttgatg
    12661 gatcaagaaa cgtccaaaac gattatggcg atttcgaaag atttgaaaga gtcaagaagg
    12721 aaaatttatt atcacattga caaaatcaat gctgctctgg gtgacgaggc gcttcacatc
    12781 attagtattc cacgaattgg tattcactta acggaagagc agagagatgc ttgttgtaaa
    12841 ctattatcgg aagtagattc gtacgattat atcatgagtg cgcatgaacg tatgatgata
    12901 atgttactat ggataggtat ttctaaagaa cgtattacga ttgaaaaatt gatagagtta
    12961 acagaggtat ctaggaatac tgttctcaat gatttgaata gtattcgtta tcaactaact
    13021 ttggaacaat atcaggtgat cttgcaagtg agcaagtcac agggatacca ccttcatgcc
    13081 caccctctta ataaaattca gtatcttcaa tcgcttctat atcatatttt tatggaagaa
    13141 aatgccactt ttgtatctat tttagaagat aagatgaaag agaggttaga tgatgagtgt
    13201 ttgctttctg ttgaaatgaa ccaatttttt aaggaacagg ttcctttagt tgaacaagat
    13261 ttagggaaga aaataaacca tcatgaaata acttttatgt tgcaggttct accttatttg
    13321 ctgttaagct gtcataatgt tgaacagtat caagaaagac atcaggatat agagaaagaa
    13381 ttttctttga taagaaaaag aatagagtat caggtgtcta agaaattagg agaacggttg
    13441 tttcaaaagt ttgaaatttc tttgtcagga cttgaagttt ctcttgtagc tgttctcctc
    13501 ctctcctatc gtaaagattt ggatattcat gcagaaagtg atgattttcg gcaattaaaa
    13561 cttgctttag aagaatttat ctggtatttt gaatcacaaa tccgaatgga gattgagaac
    13621 aaggatgatt tgttacgaaa tttgatgatc cactgtaaag ccttgttatt tagaaagact
    13681 tacggtattt tttctaaaaa tcctctaaca aaacaaattc gatccaagta tggagaatta
    13741 tttttagtca ctagaaaatc tgcggaaatt ttagaaggag catggtttat tcggctaaca
    13801 gacgatgata ttgtctattt gacgattcat attggaggat ttttaaaata tacaccatcg
    13861 tctcaaaaaa atatgaaaaa agtttatctc gtttgtgatg aaggtgttgc ggtttcgaga
    13921 cttttgctga aacaatgcaa actttatttt ccaaatgagc aaattgacac tgtatttaca
    13981 acagaacaat ttaagagtgt ggaagatatt gcacaagttg atgtagtgat tactactaat
    14041 gatgatttgg atagcagatt tccgatttta agggttaatc ctatccttga agcagaagat
    14101 attttgaaaa tgctagacta tcttaaacac aatatatttc gtaataagag caaaagtttc
    14161 agtgaaaatc tttctagtct tatttcgtct tatattgtag atagcaagtt ggctagtaag
    14221 ttccaagaag aggttcaaac acttataaat caagaaatag tagttcaagc ttttttggaa
    14281 gatatttgaa ggacagtcca atgatgaaca caaacctgtg tttttcttgg tcttttttag
    14341 tgttttgaag ggtggtatac taatctcaaa gataacaatt atatccaaag gaggcaacat
    14401 atgccaaacg tcaaagaaat tacaagagag tcatggattt tagccacttt cccagagtgg
    14461 ggaacatggt tgaacgaaga aatcgaagaa gaagtcgtac ctgaaggcaa ctttgccatg
    14521 tggtggctag gcaactgtgg tacttggatt aagacaccag ctggtgctaa cgttgtcatg
    14581 gacctttggt caaaccgtgg aaaatcaacc aaaaaagtga aagatatggt tcgtgggcac
    14641 caaatggcaa atatggcagg tgttcgtaag ttgcaaccaa acttgcgtgt tcagccaatg
    14701 gttatcgatc catttgctat caacgaacta gactattact tagtttcaca cttccacagt
    14761 gatcatatcg acccatacac agctgcagca attctcaaca atcctaagtt agagcatgtt
    14821 aagtttatcg gtccttacca ctgtggacga atctgggaag gatggggtgt tccaaaagaa
    14881 cgtatcatcg ttgttaaacc aggtgacact atcgaattaa aagatatgaa gattcatgca
    14941 gtagaatcat ttgaccgtac ttgcttggta actctcccag tgaacggtgc tgatgagaca
    15001 ggcggtgaac ttgctggctt ggctgttaca gatgaagaaa tggctcaaaa ggctgttaac
    15061 tatatctttg aaacaccagg tggaaccatc tatcatggtg cagattctca cttctcaaac
    15121 tattttgcaa aacatggtaa agactttaaa attgatgttg ctttgaataa ctatggtgaa
    15181 aatccggtag gtatccaaga caaaatgaca tctatcgacc ttcttcgtat ggcagaaaat
    15241 ctgcgtacca aagtcattat cccagttcac tatgatatct ggtctaactt catggcttct
    15301 actaatgaga ttctagaact ttggaaaatg cgaaaagatc gcttgcaata cgatttccat
    15361 ccatttatct gggaagttgg cggtaagtac acttatcctc aagatcaaca cttagtagaa
    15421 taccatcatc cacgtggttt tgatgattgt tttgaacaag actctaacat tcaatttaaa
    15481 gctttgctat aatataaaaa tattctttgg aggttatccg tatgttgcat gatacggata
    15541 attttcatat aatagtaaaa tagaatgtgt gattcaataa tcacctcaaa tagaaaggaa
    15601 attctatgtc aaatctatct gttaatgcaa ttcgttttct aggtattgac gccattaata
    15661 aagccaactc aggtcatcca ggtgtggtta tgggagcggc tccgatggct tacagcctct
    15721 ttacaaaaca acttcatatc aatccagctc aaccaaactg gattaaccgc gaccgcttta
    15781 ttctttcagc aggtcatggt tcaatgctcc tttatgctct tcttcacctt tctggttttg
    15841 aagatgtcag catggatgag attaagagtt tccgtcaatg gggttcaaaa acaccaggtc
    15901 acccagaatt tggtcatacg gcagggattg atgctacgac aggtcctcta gggcaaggga
    15961 tttcaactgc tactggtttt gcccaagcag aacgtttctt ggcagccaaa tataaccgtg
    16021 aaggctacaa tatctttgac cactatactt acgttatctg tggagacgga gacttgatgg
    16081 aaggtgtctc aagcgaggca gcttcatacg caggtttgca aaaacttgat aagttggttg
    16141 ttctttatga ttcaaatgat atcaacttgg atggtgagac aaaggattcc tttacagaaa
    16201 gtgttcgtga ccgttacaat gcctacggtt ggcatactgc cttggttgaa aatggaacag
    16261 acttggaagc catccatgct gctatcgaaa cagcaaaagc ttcaggcaag ccatctttga
    16321 ttgaagtgaa gacggttatt ggatacggtt ctccaaacaa acaaggaact aatgctgtac
    16381 acggcgcccc tcttggagca gatgaaactg catcaactcg tcaagccctc ggttgggact
    16441 acgaaccatt tgaaattcca gaacaagtat atgctgattt caaagaacat gttgcagacc
    16501 gtggcgcatc agcttatcaa gcttggacta aattagttgc agattataaa gaagctcatc
    16561 cagaactggc tgcagaagta gaagccatca tcgacggacg tgatccagtc gaagtgactc
    16621 cagcagactt cccagcttta gaaaatggtt tttctcaagc aactcgtaat tcaagtcaag
    16681 atgccttgaa tgttgtggca gctaaattac caaccttcct aggtggatca gctgaccttg
    16741 ctcactcaaa catgacttat atcaagacgg atggacttca agacgatacc aatcgcttga
    16801 atcgtaacat tcagtttggt gttcgtgaat ttgcaatggg aacaatcttg aacgggatgg
    16861 cccttcatgg tggacttcgt gtatacggtg gaactttctt cgtcttctct gactatgtga
    16921 aggcagctgt ccgcttgtca gccttacaag gacttcctgt gacttatgtc tttacccatg
    16981 attcaatcgc agttggggaa gatggtccga ctcacgaacc agttgagcat ttagcaggtc
    17041 ttcgtgctat gccaaatcta aatgttttcc gtccagcaga tgcgcgtgaa acgcaagcag
    17101 cttggtacct tgcagtgaca agtgagaaaa caccaactgc ccttgtcttg acacgtcaaa
    17161 acttgactgt tgaagatgga acagacttcg acaaggttgc taaaggtgct tatgttgtat
    17221 atgaaaatgc agccgacttt gataccatct tgattgcgac aggttcagag gttaatcttg
    17281 ctgtctcagc tgctaaagaa ttggctagtc aaggcgaaaa aatccgcgta gtcagcatgc
    17341 catctacaga tgtctttgat aaacaagatg cagcttacaa ggaagaaatt cttccaaatg
    17401 cagtccgccg tcgtgttgca gtcgaaatgg gtgcaagtca aaactggtac aaatatgttg
    17461 gtctcgatgg tgccgttcta ggtattgata ccttcggagc ctctgcccca gcaccaaaag
    17521 tattggcaga atatggcttt actgtcgaaa atcttgtaaa agttgttcga aatttgaaat
    17581 aatcctaaaa atcagggcgt aagctctggt ttttcttacc agaaaagtaa ggtacaatct
    17641 tgtaaaagta gctgaaattt gatatagtag tcctatgtaa aagacaaagg agaaaacaat
    17701 gaatccaaat attacttttt taatcatgct tgtaggtatg atggccttga tgttctttat
    17761 gcaacgttct caaaagaaac aagctcaaaa gcgtatggaa agcttaaata aactacaaaa
    17821 aggctatgaa gtgattacaa tcggtggact ttatggaaca gtcgatgaag tagatacgga
    17881 gaagggaaca atagttcttg acgtagatgg agtttacttg acttttgaac tagctgctat
    17941 caagacagta ttaccgctga aagaaacagc ttcactagaa ggcgcaattg aaaaataaga
    18001 cgggatcacg aactcccgtt ttctataaaa gaaaggaaat gggatgaaaa aattagtctt
    18061 tgtctgtctg ggaaatattt gccgtagccc tatggccgag tttgttatga aatcaatgac
    18121 agataactac gaaatccaaa gtcgagcaac ttcctcttgg gaacatggca atccgattca
    18181 taaggggact cagggaattt ttcaagagta tgagattcct tatgacaaga acaagacatc
    18241 gcttcagatt agtaaggaag attttgaagc ctttgattat attatcggaa tggacgcttc
    18301 aaatatttct gacttacgtc agatgtgtcc agtagactgt caagataaga tttactcatt
    18361 ttcatctgaa agtgttccag acccttggta tacaggagat tttgaagaaa cctatcgacg
    18421 tgttcaagag ggctgtcaag cttggttaga acgtttagaa aaggagagtt aaggtggaaa
    18481 atcttacgaa tttttacgaa aagtatcgtg tctatctgac tcgtccacgt ttagagcttt
    18541 tggcagtagt taccattgtt ttctgtgctg tactcgtctt ttttctaaat attccaggaa
    18601 aaggtgtctt aaaactcgat aatggaacga ttgtttatga tggcagtctt gtccgtggta
    18661 aaatgaatgg ccaaggtacc attaccttcc aaaatggaga ccaatataca ggtggcttca
    18721 acaatggagc cttcaacgga aaaggtacct ttcaatctaa agaaggctgg acctacgaag
    18781 gtgattttgt aaatggtcag gctgaaggaa aagggaaact aacaacagaa caagaagtcg
    18841 tttatgaagg aacttttaaa caaggcgttt ttcaacaaaa ataaagcctc ctatcaaagg
    18901 aggtattatt agaatcacaa ggtaagcgct tacctgtgaa tccctttctt tccaaatccc
    18961 tcttccaagc aagtttgtga aataaaaaat atttgaaata aatttcacaa acttcaaaga
    19021 taaaacttga taagaaaaga aaatgagaaa agtttcacaa gagtttaaaa attctttgtg
    19081 aaatgtttat gaaactgttt acaaagttga aataatgcgt tataataaac ttgtgaaaaa
    19141 attaacaaag gatatcgttc cttgaaagct atggaggaaa atatggctga taaaaaaact
    19201 gtgacaccag aggaaaagaa actcgttgct gaaaaacacg tagatgagtt ggttcaaaaa
    19261 gctctagttg cccttgaaga aatgcgtaaa ttggatcaag aacaagttga ctacatcgtt
    19321 gccaaagcat cagtagcagc tttggatgcc cacggagaat tggctttaca tgcctttgaa
    19381 gaaacaggac gtggtgtatt tgaagacaaa gcaactaaga acttgtttgc ttgtgaacac
    19441 gtagtaaaca acatgcgcca cactaagaca gttggcgtta tcgaagaaga cgatgtaaca
    19501 ggattgactc ttattgctga accagttggt gttgtttgtg gtattactcc aacaacaaac
    19561 ccaacatcaa cagcaatctt caaatcattg atttcattga agacacgtaa cccaatcgtc
    19621 tttgccttcc atccatcagc acaagaatca tctgctcatg cagctcgtat cgtccgcgat
    19681 gcagctatcg cagctggtgc tcctgaaaac tgtgtacagt ggatcactca accatctatg
    19741 gaagcaacta gtgcccttat gaaccacgaa ggtattgcaa caatccttgc aacaggtggt
    19801 aatgccatgg ttaaagccgc atactcatgt ggtaaaccag ctcttggggt aggtgccgga
    19861 aacgttccag cttatgttga aaaatcagca aacattcgtc aagcagcaca cgatatcgtc
    19921 atgtctaaat catttgataa cggtatggtc tgtgcatctg aacaagcagt tatcattgat
    19981 aaagaaattt acgatgaatt tgtagcagag ttcaaatctt accacactta ctttgtaaac
    20041 aaaaaagaaa aagctcttct tgaagagttc tgcttcggcg tcaaagcaaa cagcaaaaac
    20101 tgtgctggtg caaaattgaa cgctgacatc gttggtaaac cagcaacttg gattgcagaa
    20161 caagcaggat ttacagttcc agaaggaaca aacattcttg ctgcagaatg taaagaagtt
    20221 ggcgaaaatg agccattgac tcgtgaaaaa ttgtcaccag ttattgcagt tttgaaatct
    20281 gaaagccgtg aagatggtat tactaaggct cgtcaaatgg ttgaatttaa cggtcttgga
    20341 cactcagcag ctatccacac agctgacgaa gaattgacta aagaatttgg taaagctgtt
    20401 aaagctattc gtgttatctg taactcacct tctacttttg gtggtatcgg ggacgtttac
    20461 aatgccttct tgccatcatt gacacttgga tgtggttctt acggacgcaa ctcagttggg
    20521 gataacgtta gtgccattaa cctcttgaat atcaaaaaag tcggaagacg gagaaataac
    20581 atgcaatgga tgaaacttcc ttcaaaaaca tactttgaac gtgattcaat tcaatacctt
    20641 caaaaatgtc gtgacgttga acgtgtcatg atcgttactg accatgccat ggtagagctt
    20701 ggtttccttg atcgtatcat cgaacaactg gaccttcgtc gcaataaggt tgtttaccaa
    20761 atctttgcgg atgtagaacc ggatccagat atcacaactg taaaccgtgg tactgagatt
    20821 atgcgtgcct tcaaaccaga taccatcatc gcactcggtg gtgggtctcc aatggatgct
    20881 gccaaagtaa tgtggctctt ctacgagcaa ccagaagtgg acttccgtga ccttgtccaa
    20941 aaattcatgg atatccgtaa acgtgccttc aagttcccat tgcttggtaa gaagactaaa
    21001 ttcatcgcga ttccaactac atctggtaca ggatctgaag taacaccatt tgccgttatc
    21061 tctgataaag caaacaaccg taaataccca atcgctgact actcattgac accaactgtg
    21121 gcaatcgtag atcctgcttt ggtattgaca gttccaggat ttgttgctgc tgatactggt
    21181 atggacgtat tgactcacgc gacagaagca tacgtatcac aaatggctag tgactacact
    21241 gatggtttag cacttcaagc cattaaattg gtctttgaaa atctcgaaag ctcagttaag
    21301 aatgcagact tccactcacg tgagaaaatg cataacgctt caacaatcgc tggtatggcc
    21361 tttgccaatg ccttcctagg tatttctcac tcaatggccc ataagattgg tgcgcaattc
    21421 cacacaatcc acggtcgtac aaatgctatc ttgcttccat acgttatccg ttacaacggt
    21481 acacgtccag ctaagacagc aacatggcct aagtacaact actaccgtgc agatgaaaaa
    21541 taccaagata tcgcacgcat gcttggactt ccagcttcta ctccagaaga aggggttgaa
    21601 tcttacgcaa aagctgtcta cgaactcggt gaacgtattg ggatccaaat gaattttaga
    21661 gaccaaggaa ttgacgaaaa agaatggaaa gaacattctc gtgaattagc cttcctggct
    21721 tatgaagacc aatgttcacc agctaaccca cgtcttccaa tggtagacca tatgcaagaa
    21781 atcatcgaag atgcatacta tggctacaaa gaaagaccag gacgccgtaa ataattgttt
    21841 atcagtctag aagcaagaca aaaactcaat ttgagggaaa gatccagtac tttttctatg
    21901 ataaaaggca tcctatcaag gtttttgaac acctgatagg atgccttttt atgatattga
    21961 ggcctttttg ccctttttga aaaactagaa tagaaacaaa atatataata gattgaaact
    22021 ggaatagtac acttctgctt ctaaaacatt gttagaattc gatttgactg tcctgatcga
    22081 tttgtcctgt tcttatttca ttttaatata taaaaaatat
//
LOCUS       DAVBOD010000030        21874 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 640-05
            SAMEA1012484-rid20186543.denovo.030, whole genome shotgun sequence.
ACCESSION   DAVBOD010000030 DAVBOD010000000
VERSION     DAVBOD010000030.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012484
            Sequence Read Archive: ERR059358
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 21874)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21874)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979948.1
            Genome Coverage       :: 595x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:03:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,266
            CDSs (total)                      :: 2,219
            Genes (coding)                    :: 2,091
            CDSs (with protein)               :: 2,091
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 71 of 128
            Pseudo Genes (incomplete)         :: 50 of 128
            Pseudo Genes (internal stop)      :: 33 of 128
            Pseudo Genes (multiple problems)  :: 22 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21874
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012484-rid20186543.denovo.030"
                     /strain="NIG 640-05"
                     /db_xref="taxon:1313"
     gene            complement(408..1604)
                     /gene="tuf"
                     /locus_tag="VQ862_001258"
     CDS             complement(408..1604)
                     /gene="tuf"
                     /locus_tag="VQ862_001258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014335040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HET3115613.1"
                     /translation="MAKEKYDRSKPHVNIGTIGHVDHGKTTLTAAITTVLARRLPSSV
                     NQPKDYASIDAAPEERERGITINTAHVEYETEKRHYAHIDAPGHADYVKNMITGAAQM
                     DGAILVVASTDGPMPQTREHILLSRQVGVKHLIVFMNKVDLVDDEELLELVEMEIRDL
                     LSEYDFPGDDLPVIQGSALKALEGDSKYEDIVMELMNTVDEYIPEPERDTDKPLLLPV
                     EDVFSITGRGTVASGRIDRGIVKVNDEIEIVGIKEETQKAVVTGVEMFRKQLDEGLAG
                     DNVGVLLRGVQRDEIERGQVIAKPGSINPHTKFKGEVYILTKEEGGRHTPFFNNYRPQ
                     FYFRTTDVTGSIELPAGTEMVMPGDNVTIDVELIHPIAVEQGTTFSIREGGRTVGSGM
                     VTEIEA"
     gene            complement(2480..3349)
                     /locus_tag="VQ862_001259"
     CDS             complement(2480..3349)
                     /locus_tag="VQ862_001259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000348128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HET3115614.1"
                     /translation="MDFTWALKYATEFLGTAILIILGNGAVANVELKGTKGHQSGWIV
                     IAVGYGMGVMIPALMFGNVSGNHINPAFTLGLAVSGLFPWAQVVPYIIAQVLGAIFGQ
                     ALVVATYRPFYLKTEKPNNILGTFSTISSIDHGTKESRYAATVNGLINEFVGSFVLFF
                     AALGLTKNFFGAEVLQFMKQKAIEAGQTVDFSDLAIKAQVAPHTASGLSVAHLALGFL
                     VMALVTSLGGPTGPALNPARDLGPRLLHAFLPKSVLGEHKGDSKWWYSWVPVVAPIAA
                     AIAAVAVFKFLYL"
     gene            complement(3572..4252)
                     /locus_tag="VQ862_001260"
     CDS             complement(3572..4252)
                     /locus_tag="VQ862_001260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HET3115615.1"
                     /translation="MVPKTATSTETKTITRIIHYVDKVTNQNVKEDVVQPVTLSRTKT
                     ENKVTGVVTYGEWTTGNWDEVISGKIDKYKDPDIPTVESQEVTSDSSDKEITVRYDRL
                     STPDKPTPEKPEIPSPQEPGTPGEPTPEKPIPQPNPEHPSVPTPNPELPNQETPTPDK
                     PTPEPGTPKTETPVNPDPEVPTYETGKREELPNTGTEANATLASAGIMTLLAGLGLGF
                     FKKKEDEK"
     gene            complement(4210..5316)
                     /locus_tag="VQ862_001261"
     CDS             complement(4210..5316)
                     /locus_tag="VQ862_001261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001021424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MucBP domain-containing protein"
                     /protein_id="HET3115616.1"
                     /translation="MNIILIAKLLRENTNTKANALNNGWVRSGSEEFKKFSHFVGVDK
                     GIVRTNVLTGKKLSDKIRKEVGSGDSKLGKGGYFSTGDVLLGKDVVSYTVQVFSENNE
                     RVGVNTQSHRVQYNLPILADFSVIQDTVEPSRTVVEKIIPKLNIPEEEKGKITEEIKK
                     KKKTSELAELILENVKVRYVDEQGRLLSLKNDTGIGEKESDGTYITNKKQLIGTSYNV
                     TDKKLSSMTTTDGKYYTFKEADTNSASLTGNIVSEGRTVTLVYRESEAPTTATVTANY
                     YKEGSQEKLAESVIKADLAIGSEYTTESKTIEGKTTTEDKEDRVITRKTTYTLVATPA
                     NAYQKTVQQLTITTVRMLRKQWFPKQQPLLRRRL"
     gene            complement(5427..5681)
                     /locus_tag="VQ862_001262"
     CDS             complement(5427..5681)
                     /locus_tag="VQ862_001262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3115617.1"
                     /translation="MLNVDQDFMSISKPNKSGSDWKKTFTVRTTNRLANDLNNVLKQV
                     DKDTPNTPTWLNSAASKAKDDDRVYKLLKTLIPGENYLSC"
     gene            complement(6039..6572)
                     /locus_tag="VQ862_001263"
     CDS             complement(6039..6572)
                     /locus_tag="VQ862_001263"
                     /inference="COORDINATES: protein motif:HMM:NF024751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
                     /protein_id="HET3115618.1"
                     /translation="MTSFKEQEPEKVAEFLDILDNLKDLPIVYIDETGIDRYLYRPYA
                     RAPRGEKVYEKISGRRFERTSIVAGQVDGEFIAPMIYKKSMTSDFFVEWFKTQLLPAL
                     KTPHVIVMGNASFHPKNILDELCIQDKHFFLPLPPYSPDLNPIEQAWAILKKKVTDLL
                     REVPTIFECLECFFKTR"
     gene            complement(6559..6774)
                     /locus_tag="VQ862_001264"
     CDS             complement(6559..6774)
                     /locus_tag="VQ862_001264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET3115619.1"
                     /translation="MGKERCEQGHIERKKRVVKNRKIPLEELKAFVEAHPDAFLREIA
                     AHFDCALPSVWAALKYIKVTLKKDDEL"
     gene            complement(6741..6884)
                     /locus_tag="VQ862_001265"
     CDS             complement(6741..6884)
                     /locus_tag="VQ862_001265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007285173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tnpB"
                     /protein_id="HET3115620.1"
                     /translation="MAYSTDFKQRALDSIKEGHSHVEAAKFFGVGVRTLFTWEKKDVN
                     KDT"
     gene            7118..8836
                     /locus_tag="VQ862_001266"
     CDS             7118..8836
                     /locus_tag="VQ862_001266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HET3115621.1"
                     /translation="MSYQENYQKWVDFVELPDYLRQDLENMDEKTKEDAFYTNLEFGT
                     AGMRGLVGAGTNRINIYVVRQATEGLARLIESKGGNEKERGVAIAYDSRHFSPEFAFE
                     SAAVLAKHGIKSYVFESLRPTPELSFAVRHLNCFAGIMVTASHNPAPFNGYKVYGEDG
                     GQMPPHDADALTTYIRAIENPFAVEVADVETEKASGLIEVIGEAVDVEYLKEVKDVNI
                     NPALIEEFGKDMKIVYTPLHGTGEMLARRALAQAGFDSVQVVEAQATADPDFSTVTSP
                     NPESQAAFALAEELGRQVGADVLVATDPDADRVGVEVLQKDGSYLNLSGNQIGAIMAK
                     YILEAHKNAGTLPENAALCKSIVSTDLVTKIAESYGATMFNVLTGFKFIAEKIQEFEE
                     KHNHTYMMGFEESFGYLIKPFVRDKDAIQAVLVVAELAAYYRSRGLTLADGIEEIYKE
                     YGYYAEKTISVTLSGVDGAEQIKAIMAKFRNNAPTEWNATAITVVEDFKAQTATVADG
                     TVTNLTTPPSDVLKYTLADGSWIAVRPSGTEPKIKFYIAVVGETNEESQAKIANIEAE
                     INAFVK"
     gene            8947..9294
                     /locus_tag="VQ862_001267"
     CDS             8947..9294
                     /locus_tag="VQ862_001267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000434646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HET3115622.1"
                     /translation="MEQFLDNIKDLEVTTVVRAQEALDKKETATFFIGRKTCPYCRKF
                     SGTLSGVVAETKAHIYFINSEEPSQLNDLQAFRSRYGIPTVPGFVHITDGQINVRCDS
                     SMSAQEIKDFAGL"
     gene            complement(9572..10408)
                     /locus_tag="VQ862_001268"
     CDS             complement(9572..10408)
                     /locus_tag="VQ862_001268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HET3115623.1"
                     /translation="MKKWMLVLVSLMTALFLVACGKNSSETSGDNWSKYQSNKSITIG
                     FDSTFVPMGFAQKDGSYAGFDIDLATAVFEKYGITVNWQPIDWDLKEAELTKGTIDLI
                     WNGYSATDERREKVAFSNSYMKNEQVLVTKKSSGITTAKDMTGKTLGAQAGSSGYADF
                     EANPEILKNIVANKEANQYQTFNEALIDLKNDRIDGLLIDRVYANYYLEAEGVLNDYN
                     VFTVGLETEAFAVGARKEDTNLVKKINEAFSSLYKDGKFQEISQKWFGEDVATKEVKE
                     GQ"
     gene            complement(10421..11050)
                     /locus_tag="VQ862_001269"
     CDS             complement(10421..11050)
                     /locus_tag="VQ862_001269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000891751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HET3115624.1"
                     /translation="MLELRNINKVFGDKQILSDFSLSIPEKQILAIVGPSGGGKTTLL
                     RMLAGLETIDSGQIFYNGQPLELDELQKRNLLGFVFQDFQLFPHLSVLENLTLSPVKT
                     MGMKQEEAEKKASGLLEQLGLGGHAEAYPFSLSGGQKQRVALARAMMIDPEIIGYDEP
                     TSALDPELRLEVEKLILQNRELGMTQIVVTHDLQFAENIADVLLKVEPK"
     gene            complement(11060..11701)
                     /locus_tag="VQ862_001270"
     CDS             complement(11060..11701)
                     /locus_tag="VQ862_001270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004253193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HET3115625.1"
                     /translation="MSYLFEILPSLLNGASTTVQVFALVLLFSIPLGVLIAFALQVHW
                     KPLHYLINIYIWVMRGTPLLLQLIFIYYVLPSIGIRLDRLPAAIIAFVLNYAAYFAEI
                     FRGGIDTIPRGQYEAAKVLKFSPFDRVRYIILPQVTKIVLPSVFNEVMSLVKDTSLVY
                     ALGISDLILASRTAANRDASLVPMFLAGAIYLILIGIVTIISKKVEKKYSYYR"
     gene            complement(11847..13076)
                     /locus_tag="VQ862_001271"
     CDS             complement(11847..13076)
                     /locus_tag="VQ862_001271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HET3115626.1"
                     /translation="MNNSQQMLQALEEQDLTKAEHYFAKALENDSSDLLYELATYLEG
                     IGFYPQAKEIYLKIVEDFPEVHLNLAAIASEDGQIEEAFTYLEEIQADSDWYVSSLAL
                     KADLYQLEGLTDVAREKLLEALTYSEDSLLILGLAELDSELENYQAAIQAYAQLDNRS
                     IYEQTGISTYQRIGFAYAQLGKFETATEFLEKSLELEYDDLTAFELASLYFDQEEYQK
                     ATLYFKQLDTISPDFEGYEYGYSQALHKEHQVQEALRIAKQGLEKNPFETRLLLAASQ
                     FSYELHDASGAENYLLTAKEDAEDTEEILLRLATIYLEQERYEDILDLQSEEPENLLT
                     KWMIARSYQEMDDLDTAYEHYQELTGDLKDNPEFLEHYIYLLRELGHFEEAKVHAHTY
                     LKLVPDDVQMQELFERL"
     gene            complement(13066..14232)
                     /locus_tag="VQ862_001272"
     CDS             complement(13066..14232)
                     /locus_tag="VQ862_001272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000435446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HET3115627.1"
                     /translation="MEQKEKHFSLSWFFKWFLDNKAITVFLVTLLLGLNLFILSKISF
                     LFSPVLDFLAVVMLPVILSGLLYYLLNPIVDWMEKHKVNRVIAITIVFVIIALFIIWG
                     LAVAIPNLQRQVLTFARNVPVYLEDIDRIVNGLVAQHLPDDFRPQLEQVLTNFSSQAT
                     VLASKVSSQAVNWVSAFISGASQVIVALIIVPFMLFYLLRDGKGLRNYLTQFIPRKLK
                     EPVGQVLSDVNQQLSNYVRGQVTVAIIVAVMFIIFFKIIGLRYAVTLGVTAGILNLVP
                     YLGSFLAMLPALVLGLIAGPVMLLKVVIVFIVEQTIEGRFVSPLILGSQLNIHPINVL
                     FVLLTSGSMFGIWGVLLGIPVYASAKVVISAIFEWYKVVSGLYELEGEEVKSEQ"
     gene            14376..15389
                     /locus_tag="VQ862_001273"
     CDS             14376..15389
                     /locus_tag="VQ862_001273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000665618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactonase family protein"
                     /protein_id="HET3115628.1"
                     /translation="MKETVYFGTYTRRTSQGIYKADFDTETGQLSNLELFAAEPSPTY
                     LAFDQHQHLYTVGSQDDKGGIAAYQTDGTVLNHVVEEGAPHCYVAVDEKRDLVYAANY
                     HKGQVLVYKRQEDGSLLLSDMDQHSGQGPHENQASPHVHYTDLTPDHYLVTCDLGTDQ
                     VITYDLDQEGKLSKLYTYHSKPGAGSRHIIFHNHYKIAYLICELNSTIEVLIYDGVGE
                     FVRMQVISTLPEAYEGFNGTAAIHLSKDGKYLYASNRGHDSIAVYTILADGSLELLEI
                     VPTHGQTPRDFDLTPNQKFLIVVHQDSDNATVFKRNCDNGRLAELSNDFHVPEAVCIR
                     FAP"
     gene            complement(15434..15853)
                     /locus_tag="VQ862_001274"
     CDS             complement(15434..15853)
                     /locus_tag="VQ862_001274"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit epsilon"
                     /protein_id="HET3115629.1"
                     /translation="MAQLTVQIVTPDGLVYDHHASYVSVRTLDGEMGILPRHENMIAV
                     LAVDEVKVKRIDDKDHVNWIAVNGGVIEIANDMITIVADSAERARDIDISRAERAKLR
                     AERAIEEAQDKHLIDQERRAKIALQRAINRINVGNRL"
     gene            complement(15864..17270)
                     /gene="atpD"
                     /locus_tag="VQ862_001275"
     CDS             complement(15864..17270)
                     /gene="atpD"
                     /locus_tag="VQ862_001275"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit beta"
                     /protein_id="HET3115630.1"
                     /translation="MSSGKIAQVIGPVVDVLFAAGEKLPEINNALVVYKNDERKTKIV
                     LEVALELGDGMVRTIAMESTDGLTRGMEVLDTGRPISVPVGKETLGRVFNVLGDTIDL
                     EDPFTEDAERQPIHKKAPTFDELSTSSEILETGIKVIDLLAPYLKGGKVGLFGGAGVG
                     KTVLIQELIHNIAQEHGGISVFTGVGERTREGNDLYWEMKESGVIEKTAMVFGQMNEP
                     PGARMRVALTGLTIAEYFRDVEGQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQP
                     TLATEMGQLQERITSTKKGSVTSIQAIYVPADDYTDPAPATAFAHLDSTTNLERKLVQ
                     LGIYPAVDPLASSSRALAPEIVGEEHYAVAAEVKRVLQRYHELQDIIAILGMDELSDE
                     EKTLVARARRIQFFLSQNFNVAEQFTGQPGSYVPVAETVRGFKEILDGKYDHLPEDAF
                     RGVGSIEDVIAKAEKMGF"
     gene            complement(17356..18234)
                     /locus_tag="VQ862_001276"
     CDS             complement(17356..18234)
                     /locus_tag="VQ862_001276"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002895995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit gamma"
                     /protein_id="HET3115631.1"
                     /translation="MAVSLNDIKTKIASTKNTSQITNAMQMVSAAKLGRSEEAARNFQ
                     VYAQKVRKLLTDILHGNGAGASTNPMLISRSVKKTGYIVITSDRGLVGGYNSSILKAV
                     MELKEEYHPDGKGFEMICIGGMGADFFKARGIQPLYELRGLADQPSFDQVRKIISKTV
                     EMYQNELFDELYVCYNHHVNTLTSQMRVEQMLPIVDLDPNEADEEYSLTFELETSREE
                     ILEQLLPQFAESMIYGAIIDAKTAENAAGMTAMQTATDNAKKVINDLTIQYNRARQAA
                     ITQEITEIVAGASALE"
     gene            complement(18250..19755)
                     /locus_tag="VQ862_001277"
     CDS             complement(18250..19755)
                     /locus_tag="VQ862_001277"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit alpha"
                     /protein_id="HET3115632.1"
                     /translation="MAINAQEISALIKQQIENFKPNFDVTETGVVTYIGDGIARAHGL
                     ENVMSGELLNFENGSYGMAQNLESTDVGIIILGDFTDIREGDTIRRTGKIMEVPVGES
                     LIGRVVDPLGRPVDGLGEIHTDKTRPVEAPAPGVMQRKSVSEPLQTGLKAIDALVPIG
                     RGQRELIIGDRQTGKTTIAIDTILNQKDQDMICIYVAIGQKESTVRTQVETLRQYGAL
                     DYTIVVTASASQPSPLLFLAPYTGVAMAEEFMYQGKHVLIVYDDLSKQAVAYRELSLL
                     LRRPPGREAFPGDVFYLHSRLLERSAKVSDELGGGSITALPFIETQAGDISAYIATNV
                     ISITDGQIFLGDGLFNAGIRPAIDAGSSVSRVGGSAQIKAMKKVAGTLRIDLASYREL
                     EAFTKFGSDLDAATQAKLNRGRRTVEVLKQPVHKPLPVEKQVTILYALTHGFLDTVPV
                     DDIVRFEEEFHTFFDAQHPEILETIRDTKDLPEEAVLDAAITEFLNQSSFQ"
     gene            complement(19770..20306)
                     /locus_tag="VQ862_001278"
     CDS             complement(19770..20306)
                     /locus_tag="VQ862_001278"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit delta"
                     /protein_id="HET3115633.1"
                     /translation="MDKKTVKVIEKYSMPFVQLVLEKGEEDRIFSDLTQIKQVVEKTG
                     LPSFLKQVAVDESDKEKTIAFFQDSVSPLLQNFIQVLAYNHRANLFYDVLVDCLNRLE
                     KETNRFEVTITSAHPLTDEQKTRLLPLIEKKMSLKVRSVKEQIDESLIGGFVIFANHK
                     TIDVSIKQQLKVVKENLK"
     gene            complement(20306..20800)
                     /gene="atpF"
                     /locus_tag="VQ862_001279"
     CDS             complement(20306..20800)
                     /gene="atpF"
                     /locus_tag="VQ862_001279"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit B"
                     /protein_id="HET3115634.1"
                     /translation="MHVTVGELIGNFILITGSFILLLVLIKKFAWSNITGIFEERAEK
                     IASDIDRAEEARQKAEVLAQKREDELAGSRKEAKTIIENAKETAEQSKANILADAKLE
                     AGHLKEKANQEIAQNKVEALQSVKGEVADLTISLAGKIISQNLDSHAHKALIDQYIDQ
                     LGEA"
     gene            complement(20814..21530)
                     /gene="atpB"
                     /locus_tag="VQ862_001280"
     CDS             complement(20814..21530)
                     /gene="atpB"
                     /locus_tag="VQ862_001280"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit A"
                     /protein_id="HET3115635.1"
                     /translation="MEESINPIISIGPVIFNLTMLAMTLLIVGVIFVFIYWASRNMTL
                     KPKGKQNVLEYVYDFVIGFTEPNIGSRYMKDYSLFFLCLFLFMVIANNLGLMTKLQTI
                     DGTNWWSSPTANLQYDLTLSFLVILLTHIESVRRRGFKKSIKSFMSPVFVIPMNILEE
                     FTNFLSLALRIFGNIFAGEVMTSLLLLLSHQAIYWYPVAFGANLAWTAFSVFISCIQA
                     YVFTLLTSVYLGNKINIEEE"
     gene            complement(21565..21765)
                     /locus_tag="VQ862_001281"
     CDS             complement(21565..21765)
                     /locus_tag="VQ862_001281"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015545704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit C"
                     /protein_id="HET3115636.1"
                     /translation="MNLTFLGLCIACMGVSVGEGLLMNGLFKSVARQPDMLSEFRSLM
                     FLGVAFIEGTFFVTLVFSFIIK"
BASE COUNT         6509 a         4701 c         3988 g         6676 t
ORIGIN      
        1 gatttcttct ttagttgatt tcatattact attgtataat gctttttgat ttgagtctag
       61 tattatactc ttcgaaaatc tcttcaaacc gcgtcagctt cgccttgtcg tatagatgtt
      121 actgacttcg tcagttctat ctacaaccta aaaacagtgt tttgaacagt ctgcagctaa
      181 ctttctataa caaaatgaaa taagaacaag acaaatcaat caagacaatc aaatcgattt
      241 ctaacaatgt tttagaagta gatgtgtact attctagttt caatatatta tagtttgctc
      301 tttgattttc attgagtatt agttcaatat ctaaaaaaag aaccttgcca agcaagattc
      361 ttttagtgtc taacttaaat aattgttctt ctgggaacta aatcgaatta agcttcgatt
      421 tctgtaacca tacctgaacc aacagtacgt ccaccctcac ggatagagaa tgtagtacct
      481 tgttctacgg cgattgggtg aatcaactca acgtcgattg tcacgttatc accaggcatt
      541 accatttcag tacctgctgg aagttcgatt gaacctgtaa cgtcagtagt acggaagtag
      601 aattgtggac ggtagttgtt gaagaatgga gtgtgacgtc caccttcttc tttagtaagg
      661 atgtagactt cacctttgaa tttagtgtgt gggttgattg aacctggttt agcgataact
      721 tgtccacgtt cgatttcatc acgttgaaca ccacgaagaa ggacacctac gttatctcca
      781 gcaagacctt cgtcaagttg tttacggaac atttcaacac cagtaacaac tgctttttga
      841 gtttcttctt tgataccaac gatttcgatt tcgtcgttga ctttaacgat accacggtcg
      901 atacgtcctg aagcaactgt accacgtcca gtaattgaga atacgtcctc gactggaaga
      961 agcaatggtt tgtcagtgtc acgttctggt tctgggatat actcatcaac tgtgttcatc
     1021 aattccataa cgatgtcttc gtatttagag tcaccttcaa gagctttaag tgctgaacct
     1081 tggataactg gaagatcgtc acctgggaag tcgtattctg acaataggtc acggatttcc
     1141 atttcaacca attcaagcaa ttcttcgtcg tcaaccaagt caactttgtt catgaagacg
     1201 ataaggtgtt taacaccaac ctgacgtgaa agaaggatgt gctcacgagt ttgtggcatt
     1261 ggtccgtcag ttgaagctac tacaaggata gctccgtcca tttgagcagc accagtgatc
     1321 atatttttaa cgtagtccgc gtgtcctgga gcgtcgatgt gagcgtagtg acgtttttca
     1381 gtttcgtact caacgtgcgc agtgttgata gtgataccgc gttcgcgttc ttctggagca
     1441 gcatcgatag acgcatagtc tttaggttgg ttaactgatg aaggcaagcg acgtgccaaa
     1501 acagttgtga tagctgcagt tagggtagtt ttaccgtggt caacgtgtcc gatagtacca
     1561 atgttaacgt gtggtttact acgatcgtat ttttcttttg ccatttgagt aaaagcctcc
     1621 aataaaatat attttataga tagacagtag gcaatacagt ctaactttcc ttactatttt
     1681 atcaaatttc agctaaattg caagtgtttt acaacgtttt tgtgaattat tcttggtaaa
     1741 aatttaacta actaatagaa agtactaaat agacttatcc ttcaaggagt tttcagcatt
     1801 atccatccac tcacttgctg aaaatgtaaa cagtctctgg tttatatagt aaaatgaaac
     1861 aagaataggg caaatcgatc aggacaatca aatcgatttc taaaaatgtt ttagaagtag
     1921 aggtgtacta ttctagtttc aatctactat acaacctcaa aactgtgttt tgaacaacct
     1981 gcggctagct tcttagtttg ccctttgatt ttcattgagt ataaaattgc agataaaacg
     2041 ataacaatca taggactcag cagagtcaat gtaggtcgaa gaatagcccc cctaatcgct
     2101 tattttatag caaaatgaaa tagaaactga acattttgtt gaggaaggta aatcaattcc
     2161 tcacaatgtt tgagaaagaa gggaggacta ttccaacttc aacccactat taatatataa
     2221 tagaatgaaa actgcacaat ttgattggag aattcaaacc aatttctaac aatgttttag
     2281 aaacaagggt ctattatttc aactgcaacc tactatagcc cattgaagct ggaatagccc
     2341 actgagactt ctaaaccact gctggagagg agtttgttta gagtttcttt catttcccta
     2401 aaaaatcaaa aagagagaac cagtctgatc ctctcttact tatagatggt gctcactcaa
     2461 atgttaaagg agctatttct tagagataaa ggaatttgaa tacagctact gccgcaattg
     2521 ctgctgcgat aggtgctact actggtaccc aagaatacca ccattttgaa tcgcctttat
     2581 gctcaccaag aactgatttt ggaaggaaag catgaaggag acgtggtccc aagtcacggg
     2641 ctgggttcaa ggcgggtcct gtaggtcctc caagtgatgt taccaaagcc ataacgagga
     2701 atccaagtgc caagtgagcc acagaaagtc ctgaagcagt gtgtggagcc acctgtgctt
     2761 taatagccaa gtcagaaaaa tcaactgttt gtcctgcttc tattgccttt tgtttcatga
     2821 attgaagcac ttcagcacca aagaagtttt tagtcaaacc aagagctgca aagaacaaaa
     2881 caaatgaacc aacaaactca ttaatcaaac cattgacagt tgctgcatag cgactttctt
     2941 ttgtaccatg gtcaatactt gaaatagttg agaaagttcc caagatgtta tttggttttt
     3001 cagttttcaa gtagaatgga cggtatgttg ccacaactaa ggcttggcca aagatagccc
     3061 ccaagacttg cgcgataatg taaggtacca cttgtgccca agggaaaaga ccgctaactg
     3121 caagccctag agtgaaagca gggttgatgt gattcccaga tacgttacca aacatcaagg
     3181 ctgggatcat aacccccata ccataaccaa cagcgatgac gatccagcca ctttggtgac
     3241 ctttcgtacc tttaagttca acgttggcaa ctgcaccatt cccaagaatg atcaaaatgg
     3301 cagttcccaa aaattcagtg gcatacttca gtgcccatgt gaaatccatt tgctagattc
     3361 tccttaaaat tttttagata ttccttattt tatcaatttt taccctattt agcaactgat
     3421 ttctggaaat atttttaaaa aaataggatt catagtttcc tagttcaacg tgcttgtaag
     3481 cgtttttatt cttcacgaaa gacctcattc tcaaaaccag gaaaaagccc acatctgtga
     3541 tcttttcctt gttcctagat tctaaaatct attatttttc atcttctttt ttcttgaaga
     3601 atcctaatcc tagaccagct aacaaggtca tgataccagc actagccaag gtagcattag
     3661 cttctgtacc tgtgtttggc aattcctctc tcttacctgt ctcataagtc ggaacttctg
     3721 ggtctggatt cactggagtt tcagtttttg gagtacctgg ttctggagtt ggtttatctg
     3781 gtgttggagt ctcttgattt ggtagttctg ggtttggtgt cggaacactt ggatgctctg
     3841 gatttggttg tgggattggt ttttctggag tcggttcacc tggagtacct ggttcctgag
     3901 gacttggaat ttctggtttt tctggagttg gtttatctgg tgttgataaa cggtcatacc
     3961 ttaccgttat ttctttatca ctagagtctg acgtaacttc ttgtgattca actgttggaa
     4021 tatctggatc tttgtacttg tcaatcttac cagatataac ctcgtcccag tttcctgttg
     4081 tccattcacc gtaggttaca actcccgtga ccttgttctc agtttttgta cggcttaagg
     4141 ttacaggttg aacaacatct tcttttacat tttggttcgt aactttatca acgtaatgaa
     4201 tgatacgcgt tatagtcttc gtctcagtag aggttgctgt tttgggaacc actgtttcct
     4261 caacattctc acggtagtaa tagtcaactg ttgcaccgtc ttctggtacg catttgcagg
     4321 agttgctacc aaggtgtatg ttgttttcct tgtgataact cggtcttctt tgtcctcagt
     4381 tgttgttttc ccttcaatag tttttgattc tgtggtatac tcagaaccta tcgctaaatc
     4441 agcttttata acagactctg ccaacttctc ttggctacct tctttatagt aattggctgt
     4501 tactgtagca gtggttggcg cttcgctttc tctataaact aaggtcactg ttctaccttc
     4561 gcttacaata ttcccagtta aacttgcaga atttgtatct gcttctttaa aagtataata
     4621 ttttccgtca gtagtagtca tgctactgag ttttttatct gtgacattgt agctggtacc
     4681 aatcagttgt tttttattgg taatgtaggt tccgtcactt tctttttctc caattccagt
     4741 atcatttttc aatgatagca aacgcccttg ttcatcaaca tagcgaactt tcacattttc
     4801 taagattagt tctgccaatt ctgaggtttt tttctttttc ttgatttctt cggttatttt
     4861 ccctttctct tcttcgggaa tatttagttt tggaatgatt ttttcaacaa cggttcgtga
     4921 tggttccaca gtatcttgga tgactgaaaa gtcagctaga attgggagat tatactgaac
     4981 acggtgactt tgagtgttta ctcctactct ttcattattc tctgaaaata cttgtacggt
     5041 ataagaaaca acatcttttc ctaatagaac atccccagta gagaaatagc cgccttttcc
     5101 tagtttgcta tctccagagc ccacttcttt cctaatctta tcagatagtt ttttaccagt
     5161 cagtacattc gttcgcacaa tccctttgtc tacccctaca aagtgggaga actttttgaa
     5221 ctcttcagaa ccagatctaa cccaaccatt attaagggca tttgcttttg tatttgtatt
     5281 ctctctcaaa agtttggcga ttagaattat attcatcggc acttagagtt gctgctatat
     5341 ctgactcttg aataccaact tccttactac catttctagc ggcagtatat gtgtatttat
     5401 ctgtttctac ttctagctga ttatccttaa catgataggt aattttctcc tggtataaga
     5461 gtcttcagta gtttatatac tctgtcatca tctttagctt tagaagcagc tgagtttagc
     5521 caagttgggg tattaggagt atctttatca acctgtttca agacattatt caagtcattt
     5581 gctagcctat tggttgtcct cactgtgaaa gttttcttcc agtctgaacc acttttatta
     5641 ggcttagata tgctcatgaa atcctggtca acattcaaca caatatcgcc ttgtttttta
     5701 gcatcttccg ttgcttctgc ttcaaattga tcatggagtt tttgttgctc tggtgtatag
     5761 tttttttatt tacacgattt aatgtactat tttttatttt agtattaaga actccattaa
     5821 tacgattttt aaattctgct tcaaaaaatc ccttaatttg ttggtgcgca agttcaacat
     5881 tcaaaccttt cttatacaag tcttcattct gatacaagtc ttcattctga acgatttcgg
     5941 ctacacggtg aatggtttga ttgtataccg tcttctctta accagcagta tccttagttt
     6001 taatgactac tcgataggtt cctttagaac cgttatagtc atctagtttt aaaaaagcat
     6061 tccaaacatt caaaaatagt tggaacttcc cttaataaat ccgtcacttt ctttttcaag
     6121 atagcccaag cttgctcaat aggattcaaa tccggtgaat aaggtggtag aggtaagaaa
     6181 aagtgtttat cttggatgca gagttcatcc aaaatgttct tgggatgaaa actagcattg
     6241 cccatgacaa taacatgagg tgtcttcaaa gcaggtagga gttgcgtttt gaaccactcc
     6301 acaaagaaat cgcttgtcat gcttttcttg taaatcatgg gagctataaa ctctccgtct
     6361 acttgtcctg caacaattga agttcgctca aaacgacgtc cgctaatctt ttcatagact
     6421 ttctcccctc taggagcccg tgcataagga cgatagaggt agcggtcgat tcctgtttca
     6481 tcaatatata cgattggtaa atcttttagg ttatccaaaa tatcaagaaa ctcagcgact
     6541 ttctctggct cttgttcctt aaagctcgtc atcttttttt aaagtgacct taatatactt
     6601 taaagctgcc catacggagg gcagagcaca atcaaaatgt gccgcaattt cccgtaaaaa
     6661 agcatctgga tgagcctcta caaaggcttt caattcctct aaaggaatct ttcggttttt
     6721 gacgactcgc tttttcctct ctatgtgtcc ttgttcacat ctttcttttc ccacgtgaag
     6781 agagttctga cgccaacacc aaaaaacttg gctgcctcga catggctgtg cccctctttg
     6841 atggaatcta atgctcgctg tttaaaatca gtactatatg ccatagcttt attataatat
     6901 gcttgtttaa aactaagcaa ctatatcaat gttttgttat tagaagactt acttttttta
     6961 ctgaaatcga atttttccta acctcaacat catataaccc caaaattcaa tctgacctgg
     7021 tttgaagaga tgttcgaagc agataaggtt ttactaaaac taaaaaaaat gatataatca
     7081 aactgattaa atgttttaaa aataaaggag aatttgaatg tcttaccaag aaaattacca
     7141 gaaatgggtt gattttgtgg agcttcctga ctaccttcgt caagatttgg aaaatatgga
     7201 cgaaaaaact aaggaagatg ccttctatac aaatcttgaa tttggtactg caggtatgcg
     7261 tggcttggtt ggtgctggta caaaccgtat caacatctac gttgttcgcc aagctactga
     7321 aggattggct cgtttgattg agtcaaaagg tggaaacgag aaagaacgcg gtgtagcaat
     7381 tgcctacgat agccgtcact tctcacctga gtttgccttt gaatctgcgg cagttcttgc
     7441 taaacacggc atcaaatctt acgtatttga aagccttcgt ccaactccag aactatcatt
     7501 tgcagttcgt catctcaact gtttcgcagg tatcatggtc acagccagcc acaaccctgc
     7561 tccatttaac ggttacaagg tttacggtga agacggtgga caaatgcctc cacacgatgc
     7621 ggacgctttg actacttata tccgtgcaat cgaaaaccca tttgcagttg aagttgctga
     7681 tgtggaaact gaaaaagctt ctggcttgat tgaagttatc ggcgaagctg ttgacgtaga
     7741 ataccttaaa gaggttaagg acgtaaacat caacccagcc ttgattgaag aatttggtaa
     7801 agacatgaag attgtctaca caccacttca tggtactggt gaaatgttgg ctcgtcgtgc
     7861 tcttgcccaa gcaggatttg actctgttca agttgttgaa gcgcaagcaa ctgctgaccc
     7921 agacttctca actgtaacat ctccaaaccc agaaagccaa gcagcctttg cccttgctga
     7981 agaacttggt cgtcaagttg gtgcagatgt tcttgtcgca actgacccag acgctgaccg
     8041 tgttggtgtt gaagttcttc aaaaagatgg tagctacctc aacctttcag gtaaccaaat
     8101 cggtgctatc atggctaaat acatcttgga agctcacaaa aacgctggaa ctcttcctga
     8161 aaatgccgct ctctgcaaat ctatcgtttc aactgacttg gtaacgaaga ttgctgaaag
     8221 ctacggcgca actatgttca acgtcttgac aggtttcaaa tttatcgctg aaaaaatcca
     8281 agaattcgaa gaaaaacaca accacactta catgatggga tttgaagaaa gcttcggtta
     8341 cttgattaaa ccatttgtac gtgataaaga tgccatccaa gccgttcttg tcgttgctga
     8401 acttgctgcc tactaccgtt ctcgtggttt gacacttgct gacggtatcg aagaaatcta
     8461 taaagaatat ggctactacg cagaaaaaac aatctctgtt actctttcag gtgtcgatgg
     8521 tgctgaacaa atcaaagcga ttatggctaa attccgcaac aatgctccaa cagaatggaa
     8581 cgcaacagct atcactgtcg tagaagactt caaggcacaa actgctactg ttgctgacgg
     8641 tactgttaca aacttgacaa ctcctccaag tgatgtgttg aaatacacac ttgctgacgg
     8701 ttcatggatt gccgttcgcc cttcaggtac agaaccaaaa atcaagttct acattgcagt
     8761 tgtaggggaa accaacgaag aatcacaagc taagattgct aacatcgaag cagaaatcaa
     8821 tgcatttgta aaataaagac ctataaaaga tgagaccaac caacctcatc ttttttcgta
     8881 tcaaatctaa gcaattttag aaactttatg gcatactaga cttatcaatg aaagcgaggt
     8941 aatctcatgg aacaattttt agataacatc aaagaccttg aagtcactac agttgtgcgt
     9001 gcgcaagaag ctcttgataa aaaagaaact gcaaccttct ttatcggtcg caaaacttgc
     9061 ccttactgcc gtaaattttc aggtacattg tcaggtgtcg tagctgaaac caaagctcac
     9121 atttacttca tcaatagtga agaaccaagc caactcaatg atttgcaagc attccgctca
     9181 cgctatggaa tcccaactgt accaggtttt gttcatatta cagatggaca aatcaacgtc
     9241 cgttgcgact cttcaatgtc agcacaagaa atcaaagatt tcgcaggatt gtaaaaaatc
     9301 agctaacaag tcttaaaatc acaaaaacgc ataatgtaag gtgcaaaaac cttgatatta
     9361 tgcgttttat tgttcctaaa acagttacat cagcatttca ttacagaaca ttttaatttt
     9421 ggaagtcaaa tcaattttta acaatgtttt agaaatcaca gtgggctatt ccatattcaa
     9481 ttatccagat tcaatcgcta ttatcgtttt cctagattac aaaaaaacta cgttttgcta
     9541 atcaaaacgc agtttcagcc actattttat cttactgtcc ttcttttact tctttggttg
     9601 ctacatcttc tccaaaccat ttttgactga tttcttggaa cttgccgtcc ttgtaaagac
     9661 tagaaaaagc ttcatttatc ttcttaacca agtttgtatc ttccttacgg gctccaaccg
     9721 caaaagcttc tgtttctagt ccaactgtaa agacattata atcgtttaaa acaccttctg
     9781 cttctaaata ataatttgca tagacacggt caatcaatag accatcaatt cgatcgtttt
     9841 tcaaatcaat caaggcttca ttaaaggttt ggtattgatt cgcttcctta ttagcgacaa
     9901 tattcttcaa aatttctgga tttgcttcaa agtccgcata accagatgaa ccagcttgag
     9961 ctcctaatgt ctttccagtc atatcctttg cagtcgtgat accagatgat ttcttcgtaa
    10021 ccaatacctg ctcattcttc atatatgagt tactgaaagc caccttttca cggcgttcgt
    10081 ctgtagcgga atagccattc caaatcagat caatcgttcc ttttgtcaat tcagcttctt
    10141 tcaaatccca atcaatcggt tgccaattta ccgtgattcc gtatttttca aaaacagctg
    10201 tagctaaatc aatatcaaat cctgcataag aaccatcttt ctgagcaaat cccattggaa
    10261 caaaagtact atcaaatcca atagtaatag acttgttaga ctggtacttt gaccaattat
    10321 ctccactagt ttcgctagaa tttttcccac aagctactaa gaacaaagca gtcatcagac
    10381 tgactaatac aagcatccat tttttcatcc atttttcctc ctatttaggt tctactttca
    10441 ataatacatc tgcgatattt tcagcaaact gcaaatcatg ggtaaccaca atctgggtca
    10501 tcccaagttc cctattttgc aagattagct tctccacttc caaacgtaat tctggatcca
    10561 gggcagaagt tggttcatcg tagccaatga tttctgggtc aatcatcata gcacgcgcca
    10621 aagccacccg ctgcttttgc ccaccagata gtgagaaagg ataggcctct gcgtgtcctc
    10681 ctagtcctaa ctgttccaag agtccactcg ccttcttctc agcctcttcc tgcttcattc
    10741 ccatggtctt cacaggcgat aaagtcaaat tttccagaac tgatagatga ggaaatagtt
    10801 gaaaatcttg gaagacaaat cccagtaggt tgcgcttctg caattcatct agctctaaag
    10861 gttgtccatt ataaaagatt tgccctgaat caatggtttc aagacctgca agcatacgta
    10921 aaagagttgt cttacctcca ccagaaggtc caacgatagc caggatttgc ttttcaggaa
    10981 tacttagact gaaatcagac aggatttgtt tgtctccaaa gactttattg atatttcgta
    11041 attctaacat agctgccccc tatctataat aactgtactt tttctcaact tttttggaaa
    11101 taattgtcac aatcccaatt aaaatcaagt aaatggctcc tgccaagaac ataggaacca
    11161 gactagcatc gcggttagca gctgttcgac tagccaagat aaggtctgaa attccgagag
    11221 catagaccaa agaagtatcc ttgaccaaac tcataacttc attaaagaca ctaggaagaa
    11281 cgatcttggt cacttggggc aagataatat agcgcactct gtcaaaaggg ctaaacttca
    11341 agaccttggc agcctcatac tgtcctcttg gaatagtgtc aattccccca cggaaaattt
    11401 ctgcaaagta agctgcatag ttgagaacaa aggcaataat agctgcagga aggcgatcta
    11461 aacgaatccc aatacttggg agcacataat agataaaaat cagttgcaag agtaaggggg
    11521 ttcctcgcat aacccagatg taaatgttaa tcagataatg gaggggcttc caatggactt
    11581 gcaaggcaaa ggcaatcaaa acgcccaagg gaatcgaaaa tagcaagacc agtgcaaaga
    11641 cctgtacagt cgtgctcgca ccattcagta aactcggtaa tatctcaaat aaataagaca
    11701 tactgcacct cctaaaagta attgttccta ttatagcatg aataaacaag attaccaagt
    11761 atttttgtaa aaagattcta ccatatacaa ataaaaaccg tagctatcaa aagagataaa
    11821 ctacagttct atatgtttaa acattcttac aatctctcaa acagttcttg catttgcaca
    11881 tcatctggaa ccagttttaa gtaagtgtga gcatggactt ttgcttcttc aaaatgtccc
    11941 aattcacgca agagatagat atagtgttcc agaaattctg gattgtcctt caaatctcct
    12001 gtcaactctt gataatgctc ataagcagta tccaaatcgt ccatttcttg ataagaacga
    12061 gcaatcatcc acttggtcaa aagattttct ggctcctcac tctgcaagtc tagaatatcc
    12121 tcataacgct cctgctccag ataaatagtg gctaaacgaa gcaagatttc ttctgtatcc
    12181 tcagcgtctt cttttgcagt aaggagataa ttttctgcac cactagcatc atgcaattca
    12241 taagaaaatt gtgaagcagc tagcaagagg cgagtttcaa agggattttt ctctaatcct
    12301 tgcttagcga tacgcagggc ttcttgaact tgatgttcct tatgtaaagc ctgactgtac
    12361 ccatactcat agccttcaaa gtcaggagaa atggtatcaa gctgcttaaa gtagagggtg
    12421 gctttttgat attcttcttg atcaaaataa agactggcca actcaaaagc tgttaagtca
    12481 tcgtattcta actccaggga tttttctaaa aactcagtag ccgtttcaaa tttccctaac
    12541 tgagcatagg caaagccaat tcgttgatag gtggaaatgc ccgtttgctc ataaatcgag
    12601 cgattatcta actgggcata ggcttgaata gccgcttggt aattttccaa ctcactatcc
    12661 aactctgcca aacccaatat caagagagaa tcctctgagt aggtcaaggc ctccaataat
    12721 ttctcacgtg ccacatctgt caaaccttcc agctggtaaa ggtctgcctt cagagccaaa
    12781 gacgagacat accagtcact gtcagcttgg atttcctcaa gataggtaaa ggcttcttct
    12841 atttgaccat cctcgctagc aattgcagct agattaagat gaacctctgg aaaatcctct
    12901 acaattttca ggtaaatttc cttggcctga ggatagaaac caatcccttc aagataagtt
    12961 gccaactcat acagaagatc acttgaatca ttttctaaag ctttggcgaa ataatgctca
    13021 gccttagtta aatcttgctc ctccaaagcc tgtaacatct gttgactatt gttcactctt
    13081 gacttcctca ccctctaatt catatagacc actgactacc ttataccatt cgaaaatggc
    13141 tgaaatgaca accttagcag aggcataaac cggaatacca agtaaaactc cccagatacc
    13201 aaacatagat cctgaagtta acaaaacaaa gagaacatta ataggatgga tgtttaattg
    13261 acttcccaaa atcaatggag agacaaaacg gccttcaata gtttgttcta caataaagac
    13321 aatcactact ttcaaaagca tgactggacc agcaatcaaa cccaatacta gggcaggaag
    13381 catggctaga aagctaccaa gataagggac cagatttaaa ataccagcag taacccccag
    13441 cgtaaccgca tagcgtagac caataatctt gaagaagatg ataaacatta ctgctacaat
    13501 aatagccact gtcacttgcc ctcgaacata gttggacaac tgttgattca catctgatag
    13561 aacttgtcca acaggttcct tcaattttct tggaatgaat tgggtcaaat agttacgcaa
    13621 gcctttccca tcacgcaaga gataaaagag catgaaagga acgataatca aggcaacaat
    13681 cacttgagaa gctccgctaa taaaggcact cacccagttg actgcctgag atgaaacctt
    13741 acttgccaaa actgtagcct ggctagaaaa attggtcaaa acttgctcta attgaggtct
    13801 gaaatcatct ggcaggtgct gggctaccaa tccattaaca atcctatcta tatcttctaa
    13861 gtaaacagga acgtttcttg caaaggtcaa aacctgacgt tgcagatttg gaatggcgac
    13921 tgccaagccc caaatgataa agagagcgat gataacaaag acaatagtga tagctataac
    13981 acgattaacc ttatgcttct ccatccaatc aacaatagga ttcaacaaat aatataacaa
    14041 accagacaaa atgactggca acatcacaac tgctaaaaag tctaaaacag gtgaaaatag
    14101 aaaactaatc ttacttaaaa taaaaagatt cagtcccaat aataaggtta ctaaaaatac
    14161 cgtaattgcc ttgttatcta aaaaccactt gaaaaaccaa gataggctaa aatgtttctc
    14221 tttttgctcc ataaatactt cctttctatt gtcctctcat tataccattt ttgaaacaaa
    14281 ataactcttt tttaaagtgc ttacatctaa ttggatatct ttaatttact tgtttttgtg
    14341 atataatagt cttatcttta cacagaggta tagtaatgaa agaaactgtt tattttggaa
    14401 cttatacacg tcgtacttct caagggattt acaaggcaga ctttgataca gaaactggtc
    14461 agctttcaaa tctagaactt tttgcagctg agccaagtcc aacctacctt gcctttgacc
    14521 agcaccaaca tttatacact gttggtagcc aagacgataa ggggggaatt gcagcctatc
    14581 aaactgacgg gactgtgtta aatcatgttg ttgaagaagg agctccccac tgttatgttg
    14641 ctgtcgatga aaagcgtgat ttggtttacg cagccaacta tcacaaggga caagtccttg
    14701 tttataaacg ccaggaagat ggtagtcttc tacttagtga tatggatcaa cacagtggcc
    14761 aaggtccaca tgaaaatcaa gcttcccccc atgttcacta tacagattta acacctgacc
    14821 actatctagt gacctgcgac ttgggaactg accaagtcat cacctatgac ctcgatcaag
    14881 aaggaaaatt atctaagctc tatacctatc acagcaagcc aggagcaggc tcacgccata
    14941 tcattttcca taaccactat aaaatcgctt atctcatttg tgaactcaat agtactatcg
    15001 aagttttaat ctacgatggc gttggcgaat ttgtacgtat gcaggttatt tcaactttac
    15061 cagaagctta cgaaggcttt aatggaaccg ctgctattca tctctctaaa gacggtaaat
    15121 acctctacgc ttctaaccgt ggccatgatt ctatcgcagt atataccatc cttgcggacg
    15181 gtagcttaga gttattagaa atcgttccaa cgcatggtca gactccacgt gattttgatt
    15241 tgacacccaa ccaaaaattt ctcattgttg tccatcaaga ctctgacaat gcaactgtct
    15301 ttaaacgtaa ttgtgacaat ggtcgtctag cagaactctc caacgacttc catgttcccg
    15361 aagcagtctg catccgtttt gctccttaaa acaccataaa aaatgaactt ggtattttca
    15421 agttcatttt ttcttatagt ctatttccga cattaatacg gttaatggca cgttgcaaag
    15481 caatcttagc acgacgttct tggtcaatca aatgtttgtc ttgtgcttct tcaattgcac
    15541 gttctgcacg aagtttggca cgttctgcac gactgatatc gatatcacga gcacgttctg
    15601 cagagtcagc gacgattgtg atcatatcat tggcaatttc aataacgcca ccgtttactg
    15661 caatccagtt cacgtgatct ttatcatcga tacgttttac ctttacttca tcaactgcta
    15721 aaaccgcaat catattttca tgtcgtggca agatccccat ctcaccatcc agagttcgaa
    15781 ccgatacata gctggcatgg tgatcataga cgagaccatc tggtgtcacg atctggacag
    15841 ttaactgagc cataggtcac ctcttaaaat cccatttttt cagcttttgc aatcacatct
    15901 tcgatagaac ctacaccacg gaaggcatct tctggcaagt ggtcgtattt accatcaagg
    15961 atttccttaa agccacgtac agtttcagca actggaacat aagaacctgg ctgaccagta
    16021 aattgttccg caacgttgaa gttttgtgac aagaagaact ggatacgacg ggcgcgagca
    16081 accaaggtct tttcttcatc agaaagctca tccataccaa ggatagcaat gatatcttgc
    16141 aattcatggt aacgttgaag gacacgtttt acttcagcag caactgcata gtgctcttct
    16201 ccaacgattt caggtgccaa ggcacgtgag cttgaagcaa gtgggtcaac ggctgggtag
    16261 atacccaatt gtaccaactt acgttccaag tttgttgttg aatccaagtg agcgaaggct
    16321 gttgctggcg ctgggtcagt atagtcatcc gctggcacat agatagcctg gatagaggtt
    16381 acagaaccct tcttggttga tgtgatacgt tcttgcaatt gacccatttc cgtagcaagt
    16441 gttggttggt aaccaacggc tgatggcata cgacccaaaa gggcagatac ttctgaacca
    16501 gcctgagtga aacggaagat attatcgata aagagaagca cgtcttggcc ttccacatca
    16561 cggaagtatt cagcgattgt caaaccagta agggcaacac gcatacgtgc tcctggtggc
    16621 tcattcatct gaccaaagac catggctgtt ttctcgataa cgcctgattc tttcatttcc
    16681 cagtaaaggt cattcccctc acgagtacgt tccccaacac cagtaaatac tgaaatacca
    16741 ccgtgctctt gggcaatgtt gtgaatcaat tcttggatta agacggtttt accaactccg
    16801 gcaccaccga aaagtccaac tttaccacct ttaaggtaag gggcaagaag gtcaataacc
    16861 ttgatccctg tttcaaggat ttcagaagag gtagacaact catcaaaagt tggagctttt
    16921 ttatgaattg gctgacgctc tgcgtcttct gtaaaaggat cttccaaatc aatggtatct
    16981 cccaaaacgt tgaagacacg tcccaaagtt tctttaccta ctggtacaga gattggacga
    17041 cccgtgtcca atacttccat tccacgagtc aacccatctg ttgattccat ggcgatagta
    17101 cgaaccatac catctcctaa ctccaaggct acttcaagga cgatttttgt ttttctttcg
    17161 tcatttttgt agacgacaag tgcattgtta atctcaggaa gtttttcccc tgctgcaaac
    17221 aaaacgtcta caacgggacc gataacctga gcaattttac ctgaactcat ctccttctcc
    17281 tattctatat aagatactgt cggttcctag ctcaactagg tcctaagttc attttcatac
    17341 gagctggact agagcctatt ctaaggcact agcacctgct acgatttctg taatttcttg
    17401 tgtaatcgcc gcctgtctgg cacggttata ctgaattgtc aaatcattga tgactttctt
    17461 agcattatct gtcgctgttt gcatggctgt catacccgca gcattctcag ctgtcttggc
    17521 atcgataatg gcaccgtaaa tcatactttc tgcaaactga ggcaacaact gctccagaat
    17581 ttcttctcgg ctggtttcca attcaaaagt caagctgtac tcttcatccg cttcatttgg
    17641 atccaagtca acaatcggaa gcatttgttc cacacgcatt tgactggtta gcgtattgac
    17701 atggtggttg tagcaaacat aaagctcatc aaagagttca ttttggtaca tttcaacagt
    17761 ttttgaaata atcttacgaa cttgatcaaa gctaggttgg tctgccaagc cacgtaattc
    17821 ataaagtggt tgaataccgc gagccttaaa gaaatcagct cccatcccac cgatacagat
    17881 catttcaaaa cctttaccgt ctgggtggta ttcttctttc aactccataa cagctttcaa
    17941 aatagaggaa ttataacctc caaccaaacc gcggtctgaa gtgataacga tatagcctgt
    18001 cttcttcaca gaacggctaa tcaacatcgg attagttgaa gcaccagctc cattaccatg
    18061 aaggatatct gtcaaaagtt tacgcacttt ctgagcgtaa acttggaagt tgcgagcagc
    18121 ttcttcagaa cgacctagct tagcagccga taccatttgc atggcattag tgatttgact
    18181 cgtatttttt gttgaggcga tttttgtttt aatatcattt agagatactg ccatctgaca
    18241 cctctattct tattggaagc tagattgatt gagaaactct gtaatcgcag catccaagac
    18301 tgcttcttct ggcaagtctt ttgtatcacg aatggtttcc aaaatctctg gatgttgagc
    18361 atcaaagaag gtatggaact cttcctcgaa acgaacaata tcatctactg gaacagtatc
    18421 caagaaacca tgtgtcaaag cataaagaat ggttacttgt ttctcaacag gtaatggttt
    18481 gtgaacaggt tgtttcaaga cctcaacggt acgacgtcca cggttcaact tagcctgtgt
    18541 tgctgcgtcc aagtcagaac caaacttagt aaaggcttcc aactcacggt atgaagcaag
    18601 gtcgatacga agtgtaccag caaccttctt catggctttg atttgtgcag aaccacctac
    18661 acgagataca gatgaacccg catcgatggc tggacgaata cctgcattga agaggccatc
    18721 gccaaggaag atttgtccat cagtgataga aatcacgttg gttgcgatat aggctgagat
    18781 atctcctgct tgtgtctcga taaatggtag ggctgtaatt gatccaccac caagttcatc
    18841 agaaacttta gctgagcgct caagcaaacg gctgtggaga tagaaaacat cccctgggaa
    18901 ggcttcacga cctggaggac gacgaagcaa gagcgatagt tcacgataag ctaccgcttg
    18961 ttttgataga tcatcgtata caatcaaaac atgcttacct tgatacataa attcttccgc
    19021 catagcaacc ccagtataag gagctaggaa gagcaatgga gatggttgtg aagcagaggc
    19081 tgtcacaacg attgtgtagt ccaaggcacc gtactgacga agtgtttcta cttgcgtacg
    19141 aactgttgat tctttttgtc caatcgcgac gtagatacag atcatatctt gatctttttg
    19201 gttcaagatt gtatcaatcg caatggttgt tttccctgtc tgacggtcac cgataatcaa
    19261 ctcacgttga ccacgaccaa tcggtacaag ggcgtcaata gctttcaaac cagtttgcaa
    19321 tggttctgaa acagacttac gttgcataac accaggagct ggtgcttcta ctggacgagt
    19381 tttatcagtg tggatttctc caagaccgtc aactggacga ccaagcggat ccacaacacg
    19441 accaatcaga ctttcaccta cagggacttc catgattttc cctgtacggc ggattgtatc
    19501 gccttcacgg atatctgtaa agtcacctag gatgataata ccaacgtctg ttgactccaa
    19561 gttttgagcc ataccataag agccgttttc aaaattcaac aactctccac tcatgacatt
    19621 ttcaaggcca tgagcacgcg cgataccgtc cccgatatag gttacaacac ctgtttcagt
    19681 cacatcaaaa ttgggtttga aattttcaat ttgttgctta attaaagcgc tgatttcttg
    19741 tgcgttaatt gccaaaagaa caccactttc tatttcaaat tttctttaac aactttaagt
    19801 tgttgtttaa tactcacatc aattgtcttg tgattggcaa aaatgacaaa accaccaatg
    19861 agactttcat cgatttgttc ttttacactc cttactttca gagacatttt tttctcaatc
    19921 aaagggagca aacgagtctt ctgttcatca gttagaggat gagcagacgt aatcgtcact
    19981 tcaaatcgat ttgtttcttt ttcaagtcgg ttcaagcaat ctacaagcac atcataaaaa
    20041 agatttgctc tgtgattgta ggccagaacc tggataaagt tttgtaataa aggcgacaca
    20101 gaatcttgga aaaaagcaat tgttttttcc ttatccgact cgtctactgc cacttgtttt
    20161 aaaaaagaag gcagacctgt tttttcaaca acttgcttga tttgagtcaa gtctgaaaag
    20221 atacggtctt cttctccttt ttcaagtacc aattggacaa aaggcatgct gtatttttca
    20281 attaccttta ctgttttctt gtccattaag cttctcctag ctgatcgata tactgatcaa
    20341 tgagtgcttt atgggcatga ctgtcaaggt tttgtgagat gattttacca gctaagctga
    20401 tggtcaaatc tgcgacctca cccttaacac tctgtaaagc ttctacttta ttttgagcaa
    20461 tttcttgatt ggctttttct tttaagtgtc ctgcttctag tttagcatct gctaagatat
    20521 tagccttact ttgctcagct gtttcctttg cattttcaat gattgtctta gcttctttac
    20581 ggctaccagc caattcatct tcgcgttttt gagccaatac ttctgctttt tgacgggctt
    20641 cttcagctct gtcaatatct gaagcaattt tttcagctct ttcttcgaaa atgcctgtaa
    20701 tattagacca tgcaaatttt ttaatcaaga ctagcaaaag aataaaagag ccagtgatta
    20761 aaataaaatt accaattaat tcacctactg ttacgtgcat cagttactcc tttctattcc
    20821 tcttcaatat taatcttatt ccctaaatac acagatgtca aaagagtaaa aacataagct
    20881 tggatgcagg aaataaagac agaaaatgca gtccaagcca aattagctcc aaaggctact
    20941 ggataccaat aaatagcttg gtgggaaaga agaagtaaca aactcgtcat gacctctcct
    21001 gcaaagatat tcccaaaaat ccgcaaagcc aaagataaga agtttgtaaa ttcttccaag
    21061 atattcatcg gtatgacaaa aacaggactc ataaaagatt ttatactttt tttaaatcca
    21121 cgacgacgaa cgctttctat atgtgtcaac aaaatgacaa gaaaagataa ggttaagtca
    21181 tactgtaaat tagcggttgg cgaactccac cagttagtcc catcgatcgt ttgaagcttt
    21241 gtcattaagc caaggttatt ggcaatcacc atgaaaagga ataaacaaag gaaaaagagt
    21301 gagtaatctt tcatgtagcg cgaaccaatg ttaggttctg taaatccaat aacaaagtca
    21361 tagacatact caagtacatt ttgctttcct ttgggtttca aggtcatatt gcggcttgcc
    21421 caataaataa agacaaaaat aactcccaca atcaacaaag tcatggctaa catagtcaga
    21481 ttgaagataa caggaccaat agagatgatt ggattaatac tttcttccat ctaaaatcct
    21541 cccttttctt ctcgttccat gtatttattt gataataaat gagaagacaa gagttacaaa
    21601 gaaagttcct tcaataaagg caacacctaa aaacatcaaa ctacgaaact cagaaagcat
    21661 atctggttgg cgtgctactg atttaaacag tccattcatc aataaacctt caccgacaga
    21721 tacgcccata caggcaatac ataagcctaa aaatgttaaa ttcataacaa attctccttt
    21781 aaaataaaat ttacttactt agtgtagtcc taaaatttaa atttgtcaac ttttaaccgc
    21841 tattggaagc gtttaataaa aattatttcc attt
//
LOCUS       DAVBOD010000031        21551 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 640-05
            SAMEA1012484-rid20186543.denovo.031, whole genome shotgun sequence.
ACCESSION   DAVBOD010000031 DAVBOD010000000
VERSION     DAVBOD010000031.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012484
            Sequence Read Archive: ERR059358
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 21551)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21551)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979948.1
            Genome Coverage       :: 595x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:03:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,266
            CDSs (total)                      :: 2,219
            Genes (coding)                    :: 2,091
            CDSs (with protein)               :: 2,091
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 71 of 128
            Pseudo Genes (incomplete)         :: 50 of 128
            Pseudo Genes (internal stop)      :: 33 of 128
            Pseudo Genes (multiple problems)  :: 22 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21551
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012484-rid20186543.denovo.031"
                     /strain="NIG 640-05"
                     /db_xref="taxon:1313"
     gene            1..1024
                     /locus_tag="VQ862_001282"
                     /pseudo
     CDS             1..1024
                     /locus_tag="VQ862_001282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
     gene            complement(1417..3144)
                     /gene="ezrA"
                     /locus_tag="VQ862_001283"
     CDS             complement(1417..3144)
                     /gene="ezrA"
                     /locus_tag="VQ862_001283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000064817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septation ring formation regulator EzrA"
                     /protein_id="HET3115637.1"
                     /translation="MSNGQLIYLMVAIAVILVLAYVVAIFLRKRNEGRLEALEERKEE
                     LYNLPVNDEVEAVKNMHLIGQSQVAFREWNQKWVDLSLNSFADIENNLFEAEGYNHSF
                     RFLKASHQIDQIESQITLIEEDIAAIRNALADLEKQESKNSGRVLHALDLFEELQHRV
                     AENSEQYGQALDEIEKQLENIQSEFSQFVTLNSSGDPVEAAVILDNTENHILALSHIV
                     DRVPALVTTLSTELPDQLQDLEAGYRKLIDANYHFVETDIEARFHLLYEAFKKNQENI
                     RQLELDNAEYENGQAQEEINALYDIFTREIAAQKVVENLLATLPTYLQHMKENNTLLG
                     EDIARLNKTYLLPETAASHVRRIQTELESFEAAIVEVTSNQEEPTQAYSVLEENLEDL
                     QTQLKDIEDEQISVSERLTQIEKDDINARQKANVYVNRLHTIKRYMEKRNLPGIPQTF
                     LKLFFTASNNTEDLMVELEQKMINIESVTRVLEIATNDMEALETETYNIVQYATLTEQ
                     LLQYSNRYRSFDERIQEAFNEALDIFEKEFDYHASFDKISQALEVAEPGVTNRFVTSY
                     EKTRETIRF"
     gene            complement(3226..5172)
                     /gene="gyrB"
                     /locus_tag="VQ862_001284"
     CDS             complement(3226..5172)
                     /gene="gyrB"
                     /locus_tag="VQ862_001284"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002283665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase (ATP-hydrolyzing) subunit B"
                     /protein_id="HET3115638.1"
                     /translation="MTEEIKNLQAQDYDASQIQVLEGLEAVRMRPGMYIGSTSKEGLH
                     HLVWEIVDNSIDEALAGFASHIQVFIEPDDSITVVDDGRGIPVDIQEKTGRPAVETVF
                     TVLHAGGKFGGGGYKVSGGLHGVGSSVVNALSTQLDVHVHKNGKIHYQEYRRGHVVAD
                     LEIVGDTDKTGTTVHFTPDPKIFTETTIFDFDKLNKRIQELAFLNRGLQISITDKRQG
                     LEQTKHYHYEGGIASYVEYINENKDVIFDTPIYTDGEMDDITVEVAMQYTTGYHENVM
                     SFANNIHTHEGGTHEQGFRTALTRVINDYARKNKLLKDNEDNLTGEDVREGLTAVISV
                     KHPNPQFEGQTKTKLGNSEVVKITNRLFSEAFSDFLMENPQIAKRIVEKGILAAKARV
                     AAKRAREVTRKKSGLEISNLPGKLADCSSNNPAETELFIVEGDSAGGSAKSGRNREFQ
                     AILPIRGKILNVEKASMDKILANEEIRSLFTAMGTGFGAEFDVSKARYQKLVLMTDAD
                     VDGAHIRTLLLTLIYRYMKPILEAGYVYIAQPPIYGVKVGSEIKEYIQPGADQEIKLQ
                     EALARYSEGRTKPTIQRYKGLGEMDDHQLWETTMDPEHRLMARVSVDDAAEADKIFDM
                     LMGDRVEPRREFIEENAVYSTLDV"
     gene            complement(5187..5750)
                     /locus_tag="VQ862_001285"
     CDS             complement(5187..5750)
                     /locus_tag="VQ862_001285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HET3115639.1"
                     /translation="MKYHDYIWDLGGTLLDNYETSTAAFVETLALYGITQDHDSVYQA
                     LKVSTPFAIETFAPNLENFLEKYKENEARELEHPILFEGVSDLLEVISNQGGRHFLVS
                     HRNDQVLEILEKTSIAAYFTEVVTSSSGFKRKPNPESMLYLREKYQISSGLVIGDRPI
                     DIEAGQAAGLDTHLFTSIVNLRQVLDI"
     gene            complement(5835..6389)
                     /locus_tag="VQ862_001286"
     CDS             complement(5835..6389)
                     /locus_tag="VQ862_001286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DJ-1/PfpI family protein"
                     /protein_id="HET3115640.1"
                     /translation="MVKVAVMLAQGFEEIEALTVVDVLRRANITCDMVGFEEQVTGSH
                     AIQVRADHVFDGDLSDYDMIVLPGGMPGSAHLRDNQTLIQELQSFEQEGKKLAAICAA
                     PIALNQAEILKNKRYTCYDGVQEQILDGHYVKETVVVDGQLTTSRGPSTALAFAYELV
                     EQLGGDAESLRTGMLYQDVFGKNQ"
     gene            complement(6400..7623)
                     /locus_tag="VQ862_001287"
     CDS             complement(6400..7623)
                     /locus_tag="VQ862_001287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000830656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HET3115641.1"
                     /translation="MKRSLDSRVDYSLLLPVFFLLVIGVVAIYIAVSHDYPNNILPIL
                     GQQVAWIALGLVIGFVVMLFNTEFLWKVTPFLYILGLGLMILPIVFYNPSLVASTGAK
                     NWVSINGITLFQPSEFMKISYILMLARVIVQFTKKHKEWRRTVPLDFLLIFWMILFTI
                     PVLVLLALQSDLGTALVFVAIFSGIVLLSGVSWKIIIPVFVTAVTGVAGFLAIFISKD
                     GRAFLHQIGMPTYQINRILAWLNPFEFAQTTTYQQAQGQIAIGSGGLFGQGFNASNLL
                     IPVRESDMIFTVIAEDFGFIGSVLVIALYLMLIYRMLKITLKSNNQFYTYISTGLIMM
                     LLFHIFENIGAVTGLLPLTGIPLPFISQGGSAIISNLIGVGLLLSMSYQTNLAEEKSG
                     KVPFKRKKVVLKQIK"
     gene            complement(7660..10110)
                     /locus_tag="VQ862_001288"
     CDS             complement(7660..10110)
                     /locus_tag="VQ862_001288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional DnaQ family
                     exonuclease/ATP-dependent helicase"
                     /protein_id="HET3115642.1"
                     /translation="MKTIGNRYVVVDLEATSTGSKAKIIQVGIVVIEDGEIVDHYTTD
                     VNPHEPLDAHIKELTGLTDQRLAQAPDFSQVARKIFDLVEDGIFVAHNVQFDANLLAE
                     NLFFEGYELRNPRVDTVELAQVFFPELEKYSLPILCRELGIPLKHAHTALSDAQATAE
                     LLLFLREKMTQLPKGLLERLLEMADALLYESYLVIEETYRNQSILSSPDLVQVQGLYF
                     KKMAASLEPRKLSQDFSKNISLLNLEVREEQESFAKEVGLLLKDEPVSLIQAPTGIGK
                     TYGYLLPALSQSKERQIVLSVPTKILQNQIMEEEGKRLKEVFHTDIHSLKGPQNYLKL
                     DAFYHSLQENDENRLFRRFKMQVLVWLTETETGDLDEIGQLYRYQHFLADLRHDGNLS
                     SQNLFVTEDFWKRSQERAETCKLLVTNHAYLVTRLEDNPEFVSDRLLIIDEVQKILLA
                     LENLLQETYDIQSIIDLIDKALVGEENRVQQRILESIRFECLYLIEQFQSGKSRKNIL
                     DSLDNLHQYFSELEVEGFDELVRYFTAEGDYWLEVTETSQKKIQISSTKSGRTLLSSL
                     LPESCQVLGVSATLEISQRVSLADLLGYPEVKFVKIESREKQEQEVVMVKDFPLVTET
                     SLEVYAREVAALLVEIQAFQQPILVLFTAKDMLLAVSDLLTVSHLAQYKNGDVHQLKK
                     RFEKGEQQILLGAASFWEGVDFSSHPFVIQVVPRLPFQNPQEPLTKKINQELNQEGKN
                     AFYDYQLPMAIIRLKQALGRSMRREYQRSLTLILDRRIVGKRYGKQIVASLAEEATVK
                     TISRSEVDEAIDRFFNEL"
     gene            complement(10310..11239)
                     /locus_tag="VQ862_001289"
     CDS             complement(10310..11239)
                     /locus_tag="VQ862_001289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006154193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HET3115643.1"
                     /translation="MEKIVITATAESIEQVEQLLEAGVDRIYVGEKDFGLRLPTTFSY
                     DQLREIAKLVHDAGKELIVAVNALMHQDMMDRIKPFLDFLEEIKTDYITIGDAGVFYV
                     VNRDGYSFKTIYDASTMVTSSRQINFWGQKAGASEAVLAREIPSAELFKMPEILEIPA
                     EVLVYGASVIHHSKRPLLQNYYNFTHIDDEKTHKRDLFLAEPSDPESHYSIFEDNHGT
                     HIFANNDLDLMIKLTELVEHGFTRWKLEGLYTPGQNFVEIAKLFIQARNLIQEGNFSH
                     DQAFLLDEEVRKLHPKNRFLDTGFYDYDPDMVK"
     gene            11379..11666
                     /locus_tag="VQ862_001290"
     CDS             11379..11666
                     /locus_tag="VQ862_001290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001145225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3270 domain-containing protein"
                     /protein_id="HET3115644.1"
                     /translation="MPVRKLQSYEVDYQEELNQQLPHYQAYTPEAQSDANLKEILFFI
                     NIAVFCICIAIFSFIFLALKLSTALAFAAAIGFSLLVLKVQRSIIKRKRRR"
     gene            complement(11700..13034)
                     /gene="ciaH"
                     /locus_tag="VQ862_001291"
     CDS             complement(11700..13034)
                     /gene="ciaH"
                     /locus_tag="VQ862_001291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000491790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     CiaH"
                     /protein_id="HET3115645.1"
                     /translation="MFSKLKKTWYADDFSYFIRNFGVFTLIFSTMTLIILQVMHSSLY
                     TSVDDKLHGLSENPQAVIQLAINRATEEIKDLENARADASKVEIKPNVSSNTEVILFD
                     KDFTQLLSGNRFLGLDKIKLEKKELGHIYQIQVFNSYGQEEIYRVILMETNISSVSTN
                     IKYAAVLINTSQLEQASQKHEQLIVVVMASFWILSLLASLYLARVSVRPLLESMQKQQ
                     SFVENASHELRTPLAVLQNRLETLFRKPEATIMDVSESIASSLEEVRNMRFLTTSLLN
                     LARRDDGIKPELAEVPTSFFNTTFTNYEMIASENNRVFRFENRIHRTIVTDQLLLKQL
                     MTILFDNAVKYTEEDGEIDFLISATDRNLYLLVSDNGIGISTEDKKKIFDRFYRVDKA
                     RTRQKGGFGLGLSLAKQIVDALKGTVTVKDNKPKGTIFEVKIAIQTPSKKKK"
     gene            complement(13024..13698)
                     /gene="ciaR"
                     /locus_tag="VQ862_001292"
     CDS             complement(13024..13698)
                     /gene="ciaR"
                     /locus_tag="VQ862_001292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator CiaR"
                     /protein_id="HET3115646.1"
                     /translation="MIKILLVEDDLGLSNSVFDFLDDFADVMQVFDGEEGLYEAESGV
                     YDLILLDLMLPEKNGFQVLKELREKGITTPVLIMTAKESLDDKGHGFELGADDYLTKP
                     FYLEELKMRIQALLKRSGKFNENTLTYGNIVVNLSTNTVKVEDTPVELLGKEFDLLVY
                     FLQNQNVILPKTQIFDRLWGFDSDTTISVVEVYVSKVRKKLKGTTFAENLQTLRSVGY
                     LLKDVQ"
     gene            complement(13807..16353)
                     /locus_tag="VQ862_001293"
     CDS             complement(13807..16353)
                     /locus_tag="VQ862_001293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001149089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M1 family metallopeptidase"
                     /protein_id="HET3115647.1"
                     /translation="MQAVEHFIKQFVPEHYDLFLDLSRETKTFSGKVTITGQAQSDRI
                     SLHQKDLEITSVEVAGQARPFTVDHDNEALHIELAEAGQVELVLAFSGKITDNMTGIY
                     PSYYTVDGVKKEVLSTQFESHFAREAFPCVDEPEAKATIDLSLRFDQAEGELALSNMP
                     EIDVENRKETGIWKFETTPRMSSYLLAFVAGDLQGVTAKTKNGTLVGVYSTKAHPLSN
                     LDFSLDIAVRSIEFYEDYYGVKYPIPQSLHIALPDFSAGAMENWGLVTYREVYLVVDE
                     NSTFASRQQVALVVAHELAHQWFGNLVTMKWWDDLWLNESFANMMEYVCVDTIEPSWN
                     IFEDFQTGGVPLALERDATDGVQSVHVEVKHPDEINTLFDGAIVYAKGSRLMHMLRRW
                     LGDADFAKGLHAYFEKHQYSNTIGSDLWDALGQASGRDVAAFMDSWLEQPGYPVLTVK
                     VENDVLKISQKQFFIGENEDKNRLWVVPLNSNWKGLPDTLETESIEIPGYAALLAENE
                     GALRLNTENTAHYITDYQGDLLEAVLAELETLDNTSKLQIVQERRLLAEAGHISYADL
                     LPVLDKLAKEESYLVVSAVSQVISALERFIDEGTDAETAFKGLVAKLARHNYDRLGFE
                     AKDGESDEDELVRQLAVSMMIRSNDAEASQVASQIFATHKENLAGLPAAIRSQVLINE
                     MKHHETKDLLALYLDTYTHATDAVFKRQLAAALAYSTDADNIQNLITSWKDKFVVKPQ
                     DLSAWYYQFLAHQATQKTAWSWARENWAWIKAALGGDMSFDSFVILPAHVFKTQQRLA
                     EYKEFFEPQLSDLALSRNIGMGIKEIAARVDLISREKAAVEAVVLQYGNA"
     gene            complement(16476..16916)
                     /locus_tag="VQ862_001294"
     CDS             complement(16476..16916)
                     /locus_tag="VQ862_001294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ASCH domain-containing protein"
                     /protein_id="HET3115648.1"
                     /translation="MTPQEMWNKYKQINPLIGDEIDAWAFGVEPDLLADLVFKGEKTA
                     TASAYDLYVLEDEPLPQVGTFDVILDSQNQAVCIVEITKVSVELFNQVSAQHAFKEGE
                     GDKSLAYWRQVHEDFFTDCLGEVGLTFTPESKVVLEEFRKVYPL"
     gene            complement(16891..17760)
                     /locus_tag="VQ862_001295"
     CDS             complement(16891..17760)
                     /locus_tag="VQ862_001295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PEP-utilizing enzyme, TIM barrel domain protein"
                     /protein_id="HET3115649.1"
                     /translation="MRNQLALSGEKILEKIYPQLFHHVGMIRGEYLLRELNQNIILAS
                     CQQFVKDYLETICSLYSDEEVWYRFTELTNTEANCLVGTKEFFDEGHPLFGYRGTRRL
                     LACLDEFQAEAHVVTEVYQTNPNLSVIFPFVNDADQLKQAITVLRQYGFTGKVGTMIE
                     LPSAYFDLSSILETGISKIVVGMNDLTSFVFATMRNSQWHDMESPIMLDMLRDMQDKA
                     RKNKINFAVAGYLNTSFIQKMNQLGIKCIIHYSSIPEIFDLEIDHPDHLKHIKEESKK
                     LQRSTHDTARNVE"
     gene            complement(17738..18238)
                     /locus_tag="VQ862_001296"
     CDS             complement(17738..18238)
                     /locus_tag="VQ862_001296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000403615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HET3115650.1"
                     /translation="MEIKKHFGVYAVCLENGKLLCIEKTRGPYQHRYDLPGGSQQLGE
                     GLTETLTREVMEETGFTVRSYSNPRIYDVFVREELKNFMVHHVMALYDVEMNESAPQV
                     TISEAVSDGANDSLGYIWMDIQEITEENASPLVFKVKSELLGFPELDKTSYMNWKVND
                     EKSTCP"
     gene            complement(18249..18947)
                     /locus_tag="VQ862_001297"
     CDS             complement(18249..18947)
                     /locus_tag="VQ862_001297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-ACP reductase"
                     /protein_id="HET3115651.1"
                     /translation="MTKRVLITGVSSGIGLAQARLFLEKGYQVYGVDQGEKPLLEGDF
                     HFLQRDLTLDLEPIFDWCPQVDVLCNTAGVLDDYKPLLEQTAQDIQEIFEINYIIPVE
                     LTRYYLTQMLENKKGIIINMCSIASSLAGGGGHAYTSSKHALAGFTKQLALDYAEAGI
                     QVFGIAPGAVKTAMTAADFEPGGLADWVASETPIKRWIEPEEIAELSLFLASGKASAM
                     QGQILTIDGGWSLK"
     gene            complement(18940..19176)
                     /locus_tag="VQ862_001298"
     CDS             complement(18940..19176)
                     /locus_tag="VQ862_001298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006596738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2829 domain-containing protein"
                     /protein_id="HET3115652.1"
                     /translation="MTFEEILPGLKAKKKYVRTGWGGAENYVQLFDTIEQNGLALEVT
                     PYFLINVSGEGEGFSMWSPTACDVLATDWVEVHD"
     gene            complement(19276..20202)
                     /locus_tag="VQ862_001299"
     CDS             complement(19276..20202)
                     /locus_tag="VQ862_001299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001269463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase family oxidoreductase"
                     /protein_id="HET3115653.1"
                     /translation="MRYITLGQDDKELSEIVLGMMRIKDKSVKEVEELVETALSVGIN
                     AFDLADIYGRGRCEELLGLVLKNRPDLREKMWIQSKCGIRIEEFTYFDFSKDYIIKSV
                     DGILQRLKIDHLDSLLLHRPDALMESDQVAEAFDLLYKQGKVRDFGVSNQNPMMMELL
                     KKDVKQPLAVNQLQLSAAFTPGFESAFHVNMEDSQAAMRDGSIFEYCQLHDVVIQAWS
                     VLQFGYFKGNFVGNEKFQALNQVLDRLAIKYGVTSSTIAISWILRYPAKMQAVVGTTN
                     PKHLREVSQAANFSLTRKEWYEIYLAAGNNLP"
     gene            complement(20277..21092)
                     /locus_tag="VQ862_001300"
     CDS             complement(20277..21092)
                     /locus_tag="VQ862_001300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3115654.1"
                     /translation="MKKMKYYEETSALLHEFSEENQKYFEELWESFNLAGFLYDEDYL
                     REQIYLMMLDFSEAERDGMSAEDYLGKNPKKIMKEILKGAPRSSIKESLLTPILVLAV
                     LRYYQLLSDFSKGPLLTVNLLTFLGQLLIFLIGFGLVATILRRSLVQDSPKMKIGTYI
                     VVGTIVLLVVLGYVGMASFIQEGAFYIPAPWDSLSVFTISLVICIWNWKEAVFRPFVS
                     MIIAHLVVGSLLRYYEWMGISNVFLTKVIPLAVLFIGIFVLFRGFKKIKWSEV"
     gene            complement(21096..21416)
                     /locus_tag="VQ862_001301"
     CDS             complement(21096..21416)
                     /locus_tag="VQ862_001301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000665424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HET3115655.1"
                     /translation="MKETQLLKGVLEGCVLDMIGQKERYGYELVQTLREAGFDTIVPG
                     TIYPLLQKLEKNQWIRGDMRPSPDGPDRKYFSLMKEGEERVSVFWQQWDDLSQKVEGI
                     KNGG"
BASE COUNT         6501 a         4718 c         3803 g         6529 t
ORIGIN      
        1 tcgtcaagaa gaatcaccaa atccctcgta tcatcaacca aaaaattgcg caaaagttaa
       61 ttgaaaagaa ttctatgacc gatattgccc atcagctggc catttcaact tcaactgtca
      121 ttcgaaagct caatgatttt cactttaaac atgatttttc ttgtcttcct gagattatgt
      181 cttgggatga gtatgctttt acaaagggaa agatgagctt cattgcgcaa gattttgaaa
      241 agctcgatat catcactgtt cttgaaggta gaacacaagc tgtcatccga gatcactttc
      301 ttaaatatga tagagccgtc cgatgtcgcg tcaaaatcat tactatggat atgtttagcc
      361 cttactatga cttggctaaa cagcttcgct ttcaaatttc taggctcagg ctgaaacagt
      421 ctcccaggct gtttcactcc cgaatgctaa aatcgttctt gatcgctttc atattgtaca
      481 acatcttagc cgtgctatga gtcgtgtgca tgtccaaatc atgaatcagt ttcatcgaaa
      541 atcccatgaa tacaaggcta tcaagcgcta ctggaaactc attcaacagg atagccgtaa
      601 actgagtgat aagcgatttt atcgtcctac ttttcgtatg cacttaacca ataaagagat
      661 tttaaacaag cttttgagtt attcggaaga cttgaaacac cactatcaac tctatcagct
      721 cttgcttttt catttccaga ataaggaacc agagaaattt ttcggactta ttgaggacaa
      781 tcttaagcag gctcatccta tttttcagac tgtctttaaa accttcctca aagataaaga
      841 aaagattatc aacgcccttc aactacacta ttctaatgcc aaactggaag cgaccaataa
      901 tctcatcaaa cttatcaagc gcaatgcctt tggttttcga aactttgaaa acttcaaaaa
      961 acggattttt atcgctttga acatcaaaaa agaaaggacg aaatttgtcc tttctcaagc
     1021 ttagctgact tcaacccact acagttgaca aagagcccag attaggaact atccgtgagt
     1081 tctctagtct ggagattttt caatagactt cgttattgaa cggttaccaa gttactcaaa
     1141 gtacagattt gaagctgcag ataagactga cgaaatcact ttaatactaa atgaaaatca
     1201 aaaagcaaac taagagcctc aggctgtact tgagtacggt aaggcgacgc tgacgtgatt
     1261 tgaagagatt ttcgaagagt ataaaacact gttttgaggt ggtggataaa tcggctgggc
     1321 aaaaactcaa tctcaggaga aaatgaagta aatctcccca caactataga aaaagatttg
     1381 attctgctcc tcacacaata aaatcttttt cttttattaa aaacgaatcg tttcacgtgt
     1441 tttctcatat gaggtaacaa agcgattggt tacaccaggc tctgccactt ccaatgcttg
     1501 agaaatcttg tcaaatgaag cgtgataatc aaattctttt tcaaaaatat ctaaagcttc
     1561 gttaaatgct tcttgaatgc gttcatcaaa tgagcgatag cggttagaat attgcaagag
     1621 ttgctctgtc aaagttgcat attgtacaat attataagtt tccgtttcta aagcttccat
     1681 atcattcgtt gcaatttcaa gaactcgggt aacagattca atgttaatca ttttttgttc
     1741 taactcaacc attaaatcct cggtattatt gcttgccgta aagaataact tcaagaaagt
     1801 ttgtggaata cctggcagat tgcgtttttc catgtatcgc ttgatagtat ggagacgatt
     1861 gacataaaca ttggcctttt gacgtgcatt aatatcatct ttctcaattt gtgtcaggcg
     1921 ctcactaact gaaatttgct catcttcaat atcttttagt tgagtttgta aatcctcaag
     1981 attttcttca agaactgaat aagcttgggt tggttcttct tgatttgaag ttacctcaac
     2041 aatagctgcc tcaaaactct ctaattctgt ctgaatacga cgaacatggc ttgcagctgt
     2101 ctcaggaagt aaataggtct tgttcaaacg tgcaatatct tctcccaata aagtattatt
     2161 ctctttcata tgttgaaggt aagttggaag agttgcaagt agattttcca ctactttctg
     2221 agcagcaatt tctcgagtaa aaatatcata caaggcattg atttcctctt gtgcctgtcc
     2281 attctcatat tcggcattat ccaattccaa ctgacgaata ttctcttggt ttttcttgaa
     2341 tgcttcataa agcaagtgga aacgcgcttc aatatccgtt tcaacaaaat gataattagc
     2401 atcaattagt ttacgataac cggcttccaa atcctgtaat tgatctggca attctgtaga
     2461 aagcgtagta accaaggctg gaacacgatc cacaatatga cttaaggcca aaatgtgatt
     2521 ttctgtatta tccaaaatca ctgcggcttc cacagggtca cccgatgaat tcaaggttac
     2581 aaattgtgaa aattcagatt ggatattttc taattgtttt tcaatttcat ccaaggcttg
     2641 accatactgt tctgaatttt cagcaactct atgctgaagt tcctcaaata aatccaaagc
     2701 atgaagaaca cgaccactat ttttagattc ttgcttctct aagtctgcca aagcattgcg
     2761 aattgccgca atatcttctt caatcaaagt aatttgactc tcaatttggt caatttgatg
     2821 actggccttg agaaaacgaa atgaatggtt atagccctct gcttcaaaga gattattttc
     2881 aatatcggca aaagagttga gagataaatc gacccatttt tgattccatt cacggaaagc
     2941 cacttgactt tgtccaatca agtgcatatt ttttacagct tctacttcat catttactgg
     3001 aagattgtat agttcttctt ttctttcttc tagtgcctct aatctcccct cgtttcgctt
     3061 acgtagaaag attgccacta cataagccag aactaaaatg actgcaattg caaccattaa
     3121 ataaattagt tgtccattag acatatcaaa ctcctttttt acttgaaaca atcgtaacga
     3181 ttatatcata ttttttagac caagggaact acttctccct attttttaga catcaagtgt
     3241 actatagaca gcattttctt cgataaactc acgacgaggc tctactcgat cccccatcaa
     3301 catatcaaag attttatctg cttctgcagc atcatctaca gaaactctag ccatcaagcg
     3361 atgttcggga tccatggttg tttcccacag ctgatgatcg tccatttcac ctagcccctt
     3421 ataacgctga atagtcggtt tggtacgacc ttcactataa cgggctaaag cttcttggag
     3481 tttgatttct tgatctgcac ccggctggat atattcttta atctcgcttc caaccttgac
     3541 accatagatt ggtggttggg caatataaac ataaccagct tctaggattg gtttcatata
     3601 acgataaatc aaggttaaaa gaagggtacg aatatgggct ccatcgacat cggcatcggt
     3661 catcaaaacg agtttttggt aacgggcttt cgaaacatca aattctgcgc caaatcctgt
     3721 tcccatggct gtgaaaagac tacgaatttc ttcgttagct agaatcttat ccatacttgc
     3781 tttttcaacg ttcaaaatct taccgcgaat tggaaggata gcctgaaact cacggttacg
     3841 accagatttg gctgatccac cagctgagtc tccttcgacg atgaagagtt ctgtttcagc
     3901 agggttatta gaagaacagt ctgctagttt ccctggaagg ttggaaattt ccaaaccaga
     3961 ttttttacgt gtgacttcac gcgcacgctt ggcagccaca cgagccttgg cagccaaaat
     4021 tcctttttct acgatacgtt tggcaatctg tggattttcc atgaggaaat cggagaaggc
     4081 ttcactgaag aggcgattgg taatcttgac cacttcgcta tttcccaatt tggtcttggt
     4141 ttgtccttca aactgtggat ttgggtgttt aactgagata actgcagtta atccttcgcg
     4201 aacatcttcc cctgttaaat tatcttcatt gtctttcagt aacttattct tacgagcata
     4261 atcattgata acacgagtca gtgccgtacg gaaaccttgt tcatgcgttc caccttcatg
     4321 ggtatgaata ttattggcga aactcatgac attttcatgg taacctgttg tgtactgcat
     4381 ggctacctca actgtgatat catccatctc accgtctgta tagattggtg tatcaaagat
     4441 tacatccttg ttctcgttga tatattcaac gtaactagca atcccacctt cataatgata
     4501 atgcttggtt tgttccaaac cttggcgctt atctgtaatt gaaatttgaa gaccgcgatt
     4561 tagaaaggcc aactcttgaa tccgtttatt taatttatca aaatcaaaga ttgttgtttc
     4621 agtgaagatt tttgggtccg gtgtgaagtg aacagttgtt cctgttttat ccgtatctcc
     4681 aactatttca agatctgcga caacatgacc acgacggtat tcttggtaat gaatcttacc
     4741 atttttgtga acatgaacgt ctaattgagt ggaaagggca ttaactactg acgaccccac
     4801 cccgtgaaga ccacctgaaa ccttgtatcc accaccgccg aactttcctc cagcgtgaag
     4861 gactgtaaag acggtctcaa cagcaggacg gcctgttttt tcctgaatat cgactgggat
     4921 accacgccca tcatccacaa cagtaatcga atcatctggc tcaataaaaa cttgaatatg
     4981 gctggcaaat cctgccaagg cctcgtcaat tgagttatca acaatttccc agactagatg
     5041 gtgaagacct tcttttgagg ttgatccaat gtacatccct ggacgcatac gaacagcctc
     5101 taagccctct aaaacttgaa tttgactggc atcataatcc tgtgcctgca gatttttgat
     5161 ttcttctgtc atcttattcc tttttcttat atgtctaata cttgtcttaa attcacgata
     5221 ctggtaaaca agtgggtatc aagtcctgca gcttgacctg cttcgatatc aatcggccga
     5281 tcaccaatga caagaccaga gctaatctga tacttttctc ttaaataaag catggattcg
     5341 ggatttggct ttctcttaaa gcctgagcta gaagtcacca cttctgtaaa ataagctgct
     5401 atagaggttt tttctaaaat ttccaaaacc tgatcatttc gatgagagac caaaaaatga
     5461 cggccacctt gatttgaaat gacttccaat aggtcagaaa ctccttcaaa taaaatcggg
     5521 tgttcaagct ctctggcttc attttccttg tacttttcta aaaaattctc taaattggga
     5581 gcgaatgtct caatcgcaaa aggagtagaa acctttaaag cttgatagac actgtcatgg
     5641 tcttgtgtga taccatacag tgccaatgtt tcaacaaatg cagctgttga agtttcataa
     5701 ttatccagta aagttccacc taaatcccag atgtaatcgt gatatttcat atccttcatt
     5761 atagcatttt tttatgaaaa aagcgatgat ttccctgagt tttccacata aaaaacgaga
     5821 gaataactcc cgttttactg atttttacca aagacatctt gatagagcat tcctgttcgt
     5881 aaactctctg cgtcccctcc tagttgctcc accaactcgt aggcaaaggc aagggctgtt
     5941 gaaggacccc gactggttgt caactgacca tctaccacta ctgtttcctt gacgtagtga
     6001 ccatcaagga tttgctcttg aacgccgtca taacaagtgt atcgcttatt tttcaatatc
     6061 tctgcttgat tgagggcaat tggtgccgca caaatggctg ctagtttctt cccttcttgc
     6121 tcgaagcttt gcaattcttg aatcaaggtc tgattatcac gtaaatgtgc agaaccaggc
     6181 atacctccag gaagaacaat catatcatag tctgataaat ctccatcaaa gacatgatct
     6241 gctcttactt ggattgcatg cgaacccgtt acttgctctt caaaaccaac catatcacat
     6301 gtgatattgg ctcgacgcaa gacatctaca actgtcaagg cttcaatttc ttcaaagccc
     6361 tgagctaaca taactgctac ttttaccatg attttctcct tatttaattt gttttaatac
     6421 aacctttttc cgtttgaatg ggacttttcc gctcttttct tcagctagat tagtctggta
     6481 actcatcgat aaaagcaaac caacaccaat cagattactg ataatagctg atcccccttg
     6541 cgaaataaaa ggcaagggaa tccccgtcaa aggaagtagt ccagtcacag caccgatatt
     6601 ctcaaagatg tggaagagca acatcataat caaacctgtg gaaatataag tgtagaactg
     6661 gttatttgat ttaagagtaa tcttcaacat acggtaaatc aacatgagat agagggcaat
     6721 aaccaggaca gagccaataa agccaaaatc ttctgcaata accgtaaaaa tcatatctga
     6781 ctctcgaact gggataagca gattcgaagc attaaatccc tgaccaaata agccaccact
     6841 cccaatggca atctgtcctt gagcctgctg gtaagtcgtt gtttgggcaa actcaaaggg
     6901 attgagccaa gccaaaatcc gattaatttg gtaggtcggc attccaatct ggtgaagaaa
     6961 agctcgtccg tccttgctaa taaagatagc taagaaacca gcaactcctg ttacagcagt
     7021 cacaaatact gggataataa ttttccaaga aacccctgat aataaaacga ttcctgagaa
     7081 aatggctaca aaaaccaaag ccgtccccaa gtcactttga agtgctaaaa gaactaggac
     7141 tggaatggta aagagaatca tccagaaaat taacaaaaag tccagcggaa ccgtgcgtct
     7201 ccattcctta tgtttctttg taaattggac aatgacacga gccaacatga ggatatagga
     7261 tatcttcata aattctgacg gttggaatag ggtaattcca tttattgata cccagttttt
     7321 ggcacccgtt gatgcaacta agcttggatt ataaaataca atcggcaaga tcataagtcc
     7381 caagcctaaa atatatagaa agggggtcac cttccaaaga aattctgtat taaagagcat
     7441 gaccacaaaa ccaatcacaa gccccaaggc aatccaggcg acctgctgcc ctaaaatggg
     7501 cagaatatta ttgggataat catgactaac ggctatatag atagccacca caccgatgac
     7561 cagtagaaaa aatactggca agagcaaact gtaatcgact cttgagtcga gagaacgttt
     7621 catatatact aaccttatac tttcatacaa tactatttat caaagttcat taaaaaatct
     7681 atcaatagcc tcgtcaactt cggatcgaga gatggtttta acagtcgctt cttctgctag
     7741 agatgctact atttgtttgc cgtatcgttt tccgacgatt ctcctatcca aaataagagt
     7801 taaggaacgt tggtattcac gtctcatact tcttcccaaa gcctgtttta aacgaataat
     7861 ggccattggc aattgataat cataaaaggc atttttccct tcttgattca gttcttgatt
     7921 aatctttttc gtcaagggtt cttgaggatt ttggaaagga agcctcggta caacttgaat
     7981 cacaaaagga tggcttgaaa aatcaactcc ctcccagaaa cttgctgcac caagcaagat
     8041 ttgttgttca cctttttcaa agcgtttctt tagctgatga acatccccat ttttatactg
     8101 ggccaagtgg ctaactgtaa gtaaatccga tactgctaga agcatgtctt tagcggtaaa
     8161 gagaaccaaa atcggttgct ggaaagcttg aatttccact agtaaagcag ctacctctct
     8221 ggcatagact tctaaggagg tttctgttac cagagggaaa tctttgacca taaccacttc
     8281 ttgttcctgt ttttcccgag attcaatctt gacaaatttg acttcaggat agcctaaaag
     8341 gtctgccaaa gaaaccctct gactaatctc aagagtagct gatactccca agacttggca
     8401 actctcagga agtaaagagg acagaagagt acggcctgat tttgtagaag aaatctgaat
     8461 tttcttttga ctcgtttcag ttacttcaag ccagtaatca ccttcagctg taaaatagcg
     8521 aaccagctca tcaaagcctt ctacttctaa ttctgaaaaa tactgatgga gattgtccag
     8581 agaatctaag atatttttcc tagatttacc agactgaaat tgttctatca agtagagaca
     8641 ctcaaagcga atactttcta gtatccgttg ttgaaccctg ttttcttctc ctactaaagc
     8701 cttatcaatt aaatcgataa tagattgtat atcgtaggtc tcttgaagca gattttctag
     8761 agctaacaaa atcttttgga cttcatcaat aatcagtaaa cggtcactga caaattcagg
     8821 attatcttca agtctggtta cgagataggc atgattagtc actaaaagct tgcaagtctc
     8881 tgccctttct tgactacgtt tccaaaaatc ttccgtcaca aataagttct gggatgataa
     8941 attcccatca tgacgaaggt ctgctagaaa atgttggtaa cggtagagtt gcccgatttc
     9001 atccaaatct cctgtctctg tctcagtaag ccagaccaag acttgcattt taaagcgtct
     9061 aaataagcga ttttcatcat tttcctgcaa ggaatgataa aaggcatcca acttcagata
     9121 attttgtggt ccctttaagc tatgaatatc tgtatggaac acttccttga ggcgtttacc
     9181 ttcttcttcc atgatttgat tttgaagaat ctttgtcgga acactaagaa caatttgtcg
     9241 ctctttggat tgagataaag cgggtaagag atagccatag gttttcccaa tccctgtcgg
     9301 cgcttgaatc agagagacag gttcatcttt caatagcaag ccaacctctt tagcaaaact
     9361 ttcttgttcc tccctcactt caaggttcaa cagagaaata tttttagaaa agtcttgaga
     9421 tagttttcgt ggctccagag aagctgccat tttcttaaaa tacagacctt gaacttggac
     9481 caagtctgga gaactcagga tagattggtt gcgataagtt tcctcaataa ccaggtagga
     9541 ctcatatagg agagcgtcag ccatttccag caagcgttcc aagagacctt taggaagctg
     9601 ggtcatcttt tcccgtaaaa aaagaagtaa ttctgctgta gcttgggcat ctgaaagggc
     9661 tgtgtgtgcg tgtttaagag gaattcctaa ttctcgacac aaaatcggca agctatattt
     9721 ttccagttca gggaaaaaga cctgggccaa ttcgaccgta tcaacacgag ggtttcttag
     9781 ctcatagcct tcaaaaaata aattttccgc caagagatta gcatcaaact gaacattatg
     9841 ggctacaaaa atcccatcct ccaccaagtc aaatattttt ctggcaactt gcgaaaaatc
     9901 aggtgcttgc gccagacgtt ggtctgtcaa tcctgtcagt tctttgatat gagcatccaa
     9961 gggttcatgt ggattgacat ccgtcgtata gtgatcgacg atttctccat cctcaatcac
    10021 gacaattccc acttggataa ttttagcctt actacctgtg ctagttgcct ctaaatccac
    10081 cacaacatag cgattaccaa tcgttttcat tataaaaaat tataccaaaa aaagggccat
    10141 ttggcaccta caaacatagg ataattttca aactcaagaa cactactttt cttaaaaatc
    10201 ccatcgaata gagcattcta gcctgctgat ttttgtaaaa tagtgaagaa atacgaaaaa
    10261 ttgagagaag aaatgtttgc atcttccttc tctcaacgaa tcatgtattt tatttaacca
    10321 tgtcaggatc gtagtcataa aatcctgtat caaggaaacg gtttttaggg tgaagtttac
    10381 gaacttcttc atccagcaag aaggcttgat catggctaaa gttgccctct tgaatcaagt
    10441 tacgcgcttg gataaagagt tttgcaatct caacaaagtt ctgaccagga gtgtagagcc
    10501 cttctagttt ccagcgagta aagccatgct ccaccaattc tgttaatttg atcatcaaat
    10561 caaggtcatt gttggcaaag atatgggtcc catgattatc ttcaaaaatg gaatagtggc
    10621 tctctggatc acttggctca gccaagaaga ggtcacgttt atgcgtcttt tcatcatcga
    10681 tatgtgtaaa gttatagtag ttttgcaaga gtggacgttt agaatgatgg atgacgctag
    10741 caccgtaaac caaaacttca gcaggaattt ccaaaatctc tggcattttg aaaagttcag
    10801 ctgatggaat ttcacgcgcc aaaacagcct cagatgcgcc agccttttgt ccccagaagt
    10861 taatctgacg actgctagtt accatggttg aagcatcgta gatggtctta aatgaataac
    10921 catcgcggtt aactacgtaa aagacgcctg catccccaat cgtaatatag tctgtcttga
    10981 tttcttccaa gaagtctaag aaaggcttga tacggtccat catatcttgg tgcatgagag
    11041 cattgaccgc aacgatcaat tccttaccag catcatgaac caacttagcg atttcacgta
    11101 attggtcata actaaaggtc gttggcagac gaaggccaaa atctttctca ccgacataga
    11161 tacggtctac gccagcttcg agtagttgtt caacttgttc aatactttca gcagttgctg
    11221 taatgacaat cttttccata agaaaaatta taccacattt ctccaaaatc atccatgctt
    11281 tgaaaatgaa aagggacttt attctttttg taacctttct gtaataattc tctgccgaaa
    11341 aaatgataaa ataggtatgt actgttaagg agagaattat gcccgtaaga aaattacaat
    11401 cctatgaggt agactatcaa gaagaattaa accagcagct tcctcattac caagcttata
    11461 cacctgaagc gcaatctgat gccaatctca aggaaatcct attttttatt aatatcgctg
    11521 ttttttgtat ctgtattgct atctttagtt ttatcttttt agcattaaaa ttatcaactg
    11581 ctcttgcctt tgccgcagca atcggattca gcttacttgt tttaaaagtt caacggtcta
    11641 ttatcaaacg aaaacgtaga agataaatcc aaaatatcgc cccagttgga gcgatatttt
    11701 tattttttct ttttagatgg tgtctgaatg gcaatcttca cttcaaagat tgttcccttg
    11761 ggtttattat ctttgacagt aacagttcct tttagagcat ctacaatttg cttggctagg
    11821 gataatccta aaccaaaacc acctttttgc cgggttctag ccttgtctac tcgataaaaa
    11881 cggtcaaaaa ttttcttttt atcttctgtc gaaataccga ttccattatc agaaacaagt
    11941 aaataaagat tgcgatcggt cgccgagata agaaaatcaa tttcaccatc ctcctcagta
    12001 tacttgacgg cattatcgaa aagaatggtc atcagttgtt tcagaagaag ctgatctgtg
    12061 acaattgttc gatggatacg attttcaaaa cggaagacac gattattttc cgaagcaatc
    12121 atctcatagt ttgtgaaagt tgtattaaaa aagctagttg gaacttctgc aagctctggc
    12181 ttaatcccat catctctccg agctaagttc agcaagcttg tcgttaaaaa acgcatattt
    12241 cggacttctt ccaaactcga tgcaatgctt tcactcacat ccataatggt agcttctggc
    12301 ttacgaaaaa gggtctctaa gcgattttgc aaaactgcga gtggagttcg taactcatga
    12361 ctggcatttt ccacaaaaga ctgttgcttc tgcatactct caagcagggg cctaacactg
    12421 accctagcta gatagagact ggcaagtaaa gacaaaatcc agaaactagc catcacgacc
    12481 acaatcaatt gctcatgctt ttgactagcc tgctccaact gactggtatt aatcaagaca
    12541 gcagcatact tgatattggt tgaaaccgaa ctaatattgg tctccatcaa aatcacacga
    12601 tagatttctt cctgcccata gctattaaaa acctgaatct ggtagatatg tcctagttct
    12661 ttcttttcta acttaatctt atccaagccc aaaaatcgat ttccagaaag aagttgagta
    12721 aagtccttat caaagagaat gacttccgta ttggaactga cattaggttt tatttctact
    12781 ttactagcgt ccgccctagc attttctaaa tctttaatct cttctgttgc cctatttata
    12841 gccagctgaa taactgcttg aggattttca ctcagtccat gaagcttatc gtccaccgaa
    12901 gtataaagac tcgaatgcat gacttgtaaa ataatcagag tcattgtaga aaaaatcagg
    12961 gtgaagacac cgaagttgcg gataaaataa ctaaagtcat ccgcatacca tgttttttta
    13021 agtttactga acatctttta aaagataccc aacactacgc aaggtttgca aattctctgc
    13081 aaaagtggtt ccctttaatt tcttacggac ttttgaaaca tagacttcga caaccgaaat
    13141 cgttgtatca ctatcaaatc cccatagacg gtcaaaaatc tgcgtcttag gcaaaatcac
    13201 attttgattt tgaaggaaat aaactagtaa atcgaactct ttccccagca attcgacagg
    13261 agtatcttca actttaacgg tattggttga taaattaacc acgatattcc cataagtcaa
    13321 ggtgttttca ttaaacttcc ctgaacgttt gagaagggcc tgaatccgca ttttaagttc
    13381 ttctaggtag aaaggtttgg tcagataatc atccgctccc agttcaaatc catgtccctt
    13441 gtcatccaaa ctttccttgg cagtcataat cagaactggt gtcgtaattc ccttttcacg
    13501 caattctttt aagacttgga aaccattttt ttctggcaac atcaaatcca gcaaaatcaa
    13561 gtcatagaca ccactctcag cttcgtagag accttcttct ccatcaaata cctgcataac
    13621 atccgcaaaa tcgtctaaaa agtcaaatac tgaatttgac agacctaggt catcctcaac
    13681 caataagatt tttatcatga gaaactcctc cttattaaaa ctattatacc aaatttgcct
    13741 taaaaaaaac tcaactctct gcattttaca tgagatagct gagttttctt tttattttag
    13801 gcttatttat gcatttccgt attgaagaac aactgcttcg actgcagctt tttcacggct
    13861 aatcaagtca acacgtgctg caatttcctt gattcccata ccgatgttac ggctaagagc
    13921 aaggtcagaa agttgcggct caaagaactc cttgtattcc gccaagcgtt gctgagtctt
    13981 aaatacatga gcaggaagga taacaaagct atcaaagctc atatctcctc caagggctgc
    14041 cttaatccaa gcccagtttt cacgcgccca agaccaagct gttttctgag ttgcttgatg
    14101 agctaggaat tggtaatacc aagcagacaa gtcctgtggt ttgaccacaa atttgtcctt
    14161 ccaagaagta atcaagtttt ggatattatc cgcatctgta ctgtatgcaa gagctgctgc
    14221 caactggcgt ttaaagacag catctgttgc gtgagtataa gtatcaagat aaagtgctaa
    14281 caagtcttta gtctcatgat gtttcatctc attaatcaga acttgtgaac gaatagctgc
    14341 tgggagtcct gcaagattct ccttgtgtgt tgcgaagatt tggctagcga cttgactagc
    14401 ttctgcatca tttgagcgaa tcatcatcga aacagccagc tgacgaacca attcatcctc
    14461 atctgattct ccgtctttag cttcaaaacc aagacggtca tagttatgac gagccaattt
    14521 agcaaccagt cctttgaagg ctgtttcagc atccgttcct tcatcaataa agcgctcaag
    14581 agctgaaatc acttgagaaa cagctgaaac caccagataa gactcttcct tagcaagttt
    14641 atcaagaact ggaagcaagt ctgcataaga aatgtgccct gcctcagcca acaaacgacg
    14701 ttcttgaaca atttgcagtt tgcttgtgtt atcaagtgtc tctagctcag caagaacagc
    14761 ttctaacaag tctccttgat agtcggtaat atagtgggca gtattttcag tgttgagacg
    14821 aagagctcct tcattttcag caagaagagc tgcgtagcca gggatttcga tactttcagt
    14881 ttcgagtgta tcaggcaagc ctttccagtt gctattgagg ggcaccaccc agagacggtt
    14941 cttgtcttcg ttctcaccga tgaagaattg tttttgtgaa atcttcaaga catcattttc
    15001 aactttgaca gtaagaactg ggtaaccagg ctgttccaac caagaatcca tgaaggctgc
    15061 gacatcacgt cctgacgctt gaccaagggc atcccaaagg tcactaccaa tggtgttgct
    15121 gtattggtgt ttttcaaagt aggcgtgcaa acctttagca aaatcagcat ctcctagcca
    15181 acggcgaagc atgtgcatga gacggcttcc tttggcatag acgatagcgc cgtcaaagag
    15241 tgtattgatt tcatctggat gtttaacttc gacgtggaca gactgaacgc catcagtagc
    15301 gtcacgttca agagcaagag gtactccacc tgtttggaaa tcttcaaaga tattccagct
    15361 tggttcgatg gtatccacac agacgtattc catcatatta gcgaaacttt cattgagcca
    15421 aaggtcatcc caccatttca tagtcacgag gttcccaaac cattggtgag ccaattcatg
    15481 agccacaaca agggcaactt gttgacggct agcaaatgta gagttttcat cgacaaccaa
    15541 gtaaacttca cggtaggtca caagacccca gttttccata gcaccagctg agaagtcagg
    15601 aagggcgatg tggagagatt gaggaattgg gtacttaact ccatagtaat cttcgtaaaa
    15661 ctcgatagag cgaacagcga tatccagtga gaaatcaaga tttgaaagtg gatgtgcttt
    15721 ggttgagtag acacctacca gggtaccatt tttagtttta gcggtcaccc cttgcaaatc
    15781 accagcaaca aaggccaaca agtaagaaga catgcgaggt gttgtctcaa acttccagat
    15841 acctgtttcc ttacggtttt caacatcgat ttctggcatg tttgacaagg ccaattcacc
    15901 ttctgcttgg tcaaagcgaa gagagaggtc aatagttgct ttggcttcag gctcatccac
    15961 acatgggaaa gcttcgcgcg caaaatggct ctcgaactga gtagacaaga cctccttctt
    16021 gactccatca actgtataat aagaagggta aatccctgtc atgttgtctg taattttacc
    16081 agaaaaggca agaaccaatt caacttgacc agcctcagcc aattcgatat gaagggcttc
    16141 attgtcatgg tcaactgtaa atggacgagc ttgacctgca acttctacag aggtgatttc
    16201 caagtctttt tggtggaggg agatgcggtc actctgtgct tgaccagtga tggtcacttt
    16261 cccagaaaaa gtcttggtct cacgactcaa atctaaaaat aaatcataat gttcaggaac
    16321 aaattgctta ataaaatgtt caactgcttg catagttttc tcctattcta agtttaagag
    16381 ctgctgctct tcttcaaaca aacttattat atcatatttt gcttgagaaa aaaggattgg
    16441 acagcgattt ccaaaacttt cttccttcta atagtctaca gtgggtagac cttgcgaaat
    16501 tcttctaaaa caaccttgct ttcaggtgta aaagtcagcc ctacttcacc caaacagtct
    16561 gtgaaaaagt cctcatgaac ctggcgccaa taggcaagtg atttgtctcc ctcaccttcc
    16621 ttaaaggcat gttgcgcaga aacttgattg aagagttcaa cagaaacctt tgtaatttcg
    16681 acaatgcaga cagcctgatt ttgactatct aaaatgacat cgaaggtccc tacttgggga
    16741 agtggttcgt cttctagtac atagaggtca taggctgatg ctgttgctgt cttttctcct
    16801 ttaaacacca aatccgctaa aaggtctggt tcaactccaa aagcccaagc atcgatttca
    16861 tctccgatca aaggattgat ttgcttgtat ttattccaca tttcttgcgg tgtcatgggt
    16921 actcctttgt aattttttac tttcttcttt tatgtgttta agatgatctg gatggtcaat
    16981 ctctaaatca aaaatctctg gaatagaact gtagtggata atgcacttga tacccaactg
    17041 attcattttt tgtatgaaag aagtattcag atagcctgct acagcaaaat taatcttgtt
    17101 ctttcttgct ttatcctgca tatctcttag catatctaac attattggac tttccatatc
    17161 atgccattga ctgtttctca tagtcgcaaa aacaaaggaa gtcaaatcat tcattccaac
    17221 tacaatcttt gaaatgcccg tttccagtat actagataag tcaaaatacg ctgacggtaa
    17281 ttcaatcatc gttccgactt tcccagtaaa gccatactga cgcaatactg taatagcttg
    17341 ttttaattgg tcggcatcat tgacaaaagg aaagataaca gatagattgg ggttggtttg
    17401 ataaacttct gtaacgacat gtgcttcagc ctgaaattca tccaaacacg ccagtaaacg
    17461 cctagttcct ctatagccaa acaagggatg cccttcgtca aaaaactctt tagtccccac
    17521 taaacaattg gcttctgtat tcgttaattc agtaaaacga taccaaactt cttcatctga
    17581 gtacagggag cagatagtct ctagataatc ttttacaaat tgctgacaac ttgctaatat
    17641 gatgttttga ttaagctctc tcaacaaata ttccccacga atcatgccga cgtggtgaaa
    17701 tagttgagga taaatttttt caagaatttt ttcgccacta agggcaagtt gatttctcat
    17761 cattcacctt ccaattcatg taagaagtct tgtccagttc tggaaatcct aataattcag
    17821 acttaacctt aaagactaat ggcgatgcat tttcttctgt aatctcttga atatccatcc
    17881 aaatatatcc aagtgaatca ttcgcaccat cagacacagc ttccgaaatc gtaacttgag
    17941 gtgcactctc attcatttca acatcataca aggccatgac atggtgaacc ataaaatttt
    18001 ttaactcttc tctgacgaaa acatcgtaga ttcgaggatt agagtagctt ctaacagtaa
    18061 atcccgtctc ttccataact tctctagtca gcgtttccgt cagtccttca ccaagttgct
    18121 gactgcctcc aggtagatca taccgatgtt gataagggcc tctcgttttt tcaatgcaga
    18181 gtaacttccc attttctaag caaacagcgt agactccaaa gtgttttttg atttccatcc
    18241 aactcctcct acttcaaaga ccagccacca tctattgtca agatttgtcc ttgcatggcg
    18301 ctcgcttttc cacttgctaa aaaaagacta agctctgcta tttcctctgg ctcaatccag
    18361 cgcttgattg gggtttcact agccacccag tcagccaaac cacctggttc aaaatccgca
    18421 gcggtcatag ctgtcttgac tgctcctgga gcgataccaa agacctgaat cccagcttca
    18481 gcatagtcta gagccaactg cttggtgaag ccagccaagg catgcttgga tgaagtatag
    18541 gcgtgaccac ctccacctgc taggctagaa gcaatggaac acatattgat gatgattccc
    18601 tttttatttt ccagcatttg tgtcaaataa taccgagtca actctactgg aataatgtag
    18661 ttgatttcaa aaatctcttg aatgtcctgc gccgtttgtt ccaacagtgg tttgtaatca
    18721 tccaaaactc cggcagtatt acacaaaaca tccacctgag ggcaccagtc aaaaataggt
    18781 tccaagtcca aggtcaaatc tctctgtaaa aagtgaaaat caccctctaa gagtggcttt
    18841 tcaccttggt caactccata aacttgatag cccttctcta aaaagaggcg agcttgagcc
    18901 aatccgatcc ctgaactcac tcctgtaatg agtacacgtt tagtcatgca cttctaccca
    18961 atccgttgcc aaaacatcac aagctgtcgg gctccacatg gaaaaacctt ctccttctcc
    19021 agacacgttg attaagaaat aaggtgtcac ttcaagtgca agcccatttt gctcgatggt
    19081 atcaaagagt tggacatagt tttcagcacc tccccaacca gttcgtacat attttttctt
    19141 agcctttaag ccaggtagaa tttcttcaaa tgtcatgttt ttctccttta atgtcaataa
    19201 ttctcccctt cattataaca aaaaaaccgc tttaaaacgg ctttttgact gtgatttatt
    19261 tacatcttct tctacttacg gcaaattatt ccctgcagca agataaattt cataccattc
    19321 ttttcttgtt aagctaaagt ttgccgcttg gctaacttct ctcaagtgct taggatttgt
    19381 ggtacctaca actgcctgca tttttgctgg ataacgcaat atccaagaaa tggcaatagt
    19441 tgaagaggtt actccatatt taatagctaa acgatcaagt acttgattta aagcttgaaa
    19501 tttctcattt ccaacaaaat tccctttaaa atacccgaat tgtaagacag accatgcttg
    19561 aatgaccaca tcgtgtaatt ggcaatattc aaaaatgctg ccatctcgca tagctgcttg
    19621 actatcttcc atattaacat gaaaagctga ttcaaatcct ggagtaaaag ccgcactcaa
    19681 ttgtagctga ttaacagcta acggctgctt gacatctttt ttaagcaact ccatcatcat
    19741 aggattttga ttagaaactc caaaatctcg aactttacct tgtttataaa ggagatcaaa
    19801 ggcttctgct acttggtcag attccatcaa agcatctggt cgatgaagga gcaagctatc
    19861 tagatgatca atcttcaatc tttgcaaaat accgtctact gattttataa tatagtcctt
    19921 agaaaaatca aaataggtaa attcttcaat gcgaatgcca catttggact gaatccacat
    19981 cttttctctt aaatctggac gattttttag gacaagacct aacagttctt cacaacgacc
    20041 acgaccataa atatcagcca agtcgaaggc attgattcca acagaaagtg ctgtttctac
    20101 aagctcttca acttctttta cagacttatc ttttattctc atcattccga gaacaatttc
    20161 tgataattct ttgtcatctt gaccaagagt tatgtatctc atcaaatttt tctcctttaa
    20221 tttctaacat tcttcccttc attataacaa aaaaccgctt tgcaacggct ttttgactat
    20281 acttcactcc attttatctt cttaaaccca cggaacaaga caaagattcc aataaagagg
    20341 acagctaaag gaataacttt tgtaaggaaa acatttgaaa ttcccatcca ctcataataa
    20401 cggagcagag aacccaccac aagatgggca ataatcatac tgacaaatgg acgaaagacc
    20461 gcttctttcc aattccaaat acagataact agcgaaatcg taaagacaga caaactatcc
    20521 cagggagccg gaatataaaa ggctccttct tgtatgaagc ttgccattcc tacatatcct
    20581 aaaacaacta aaagaactat agtcccaaca acaatgtaag tgccaatttt cattttagga
    20641 gaatcttgga ctaaacttct tcgtaaaatt gtggccacaa gtccaaatcc aatcagaaaa
    20701 ataagaagtt gccctaaaaa tgtgagcaaa ttgactgtta agagaggacc tttagaaaaa
    20761 tcacttagta gttgataata acgtaatacc gccaggacaa gaattggcgt caaaagggac
    20821 tctttgatag aactgcgagg tgctcccttg agaatctctt tcattatttt tttaggattc
    20881 ttacctagat aatcctctgc actcatgcca tctcgttctg cttctgagaa atctagcatc
    20941 atcaaataga tctgctctct gagatagtct tcatcataga gaaatccagc aagattaaaa
    21001 ctttcccaca actcctcaaa atacttttga ttctcctcag aaaactcatg tagcaaagcg
    21061 cttgtttctt cgtaatactt cattttcttc atggtttaac ccccattctt aatcccttct
    21121 actttttgac tcaaatcgtc ccattgttgc caaaagactg agacacgctc ttctccttct
    21181 ttcattaatg aaaaatactt ccgatctgga ccatctggcg acgggcgcat gtcgcctctt
    21241 atccattgat ttttttctaa cttttgcaac aaaggataaa tagttcctgg aacgatagta
    21301 tcaaatccag cctctcgcaa agtctgaacc aactcataac cataccgctc tttttgacca
    21361 atcatatcca agacacaacc ttcaagaaca ccttttaata gctgagtttc tttcatcact
    21421 tctcccttct aatctatttt gtaataccta ctagtaactt cacctatagt atatcacttc
    21481 tacactagtt tgtaaagcat aatagttaat actcttcgaa aatctcttca aaccacgtca
    21541 gcgtcgccct a
//
LOCUS       DAVBOD010000032        21449 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 640-05
            SAMEA1012484-rid20186543.denovo.032, whole genome shotgun sequence.
ACCESSION   DAVBOD010000032 DAVBOD010000000
VERSION     DAVBOD010000032.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012484
            Sequence Read Archive: ERR059358
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 21449)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21449)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979948.1
            Genome Coverage       :: 595x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:03:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,266
            CDSs (total)                      :: 2,219
            Genes (coding)                    :: 2,091
            CDSs (with protein)               :: 2,091
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 71 of 128
            Pseudo Genes (incomplete)         :: 50 of 128
            Pseudo Genes (internal stop)      :: 33 of 128
            Pseudo Genes (multiple problems)  :: 22 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21449
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012484-rid20186543.denovo.032"
                     /strain="NIG 640-05"
                     /db_xref="taxon:1313"
     gene            complement(<1..1370)
                     /locus_tag="VQ862_001302"
     CDS             complement(<1..1370)
                     /locus_tag="VQ862_001302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000458188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RICH domain-containing protein"
                     /protein_id="HET3115656.1"
                     /translation="MFASKSERKVHYSIRKFSIGVASVVVASLVMGSVVHATENEGST
                     QAATFSNMANKSQTEQGEINIERDKAKTAVSEYKEKKVSEIYTKLERDRHKDTVDLVN
                     KLQEIKNEYLNKIVQSTSKTEIQGLITTSRSKLDEAVSKYKKAPSSSSSSGSSTKPEA
                     SDTAKPNKPTELEKKVAEAEKKVEEAKKKAKDQKEEDYRNYPTITYKTLELEIAESDV
                     EVKKAELELVKEEAKEPRNEEKVKQAKAKVESEETEATRLEKIKTDRKKAEEEAKRKA
                     AEEDKVKEKPAEQPKPAPAPQPEKPAPKPENPAPKPENPAPKPEKPAEQQAEEDYARR
                     SEEEYNRLTQQQPPKTEKPAQPSTPKTGWKQENGMWYFYNTDGSMATGWLQNNGSWYY
                     LNSNGAMATGWLQNNGSWYYLNANGSMATGWLQNNGSWYYLNANGSMATGWLQYNGSW
                     YYLNANG"
     gene            complement(1449..1976)
                     /locus_tag="VQ862_001303"
     CDS             complement(1449..1976)
                     /locus_tag="VQ862_001303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenylcysteine carboxyl methyltransferase
                     family protein"
                     /protein_id="HET3115657.1"
                     /translation="MVLAIILVTFFIRLIFLKRSIENEKRILSNGGKEFGVENTKRLT
                     MAHIVFYLSCLVEAVVHKTIFDGMGMVGLVLLIFSMLMLMLVIHLLGDIWTVKLMLVN
                     NHKYVDHILFRTVKHPNYFLNILPELIGLTLLSHAYVTFVLVFPVYAVILYRRIAEEE
                     KLLHEVIIPNGSIKR"
     gene            complement(2059..3390)
                     /gene="hk06"
                     /locus_tag="VQ862_001304"
     CDS             complement(2059..3390)
                     /gene="hk06"
                     /locus_tag="VQ862_001304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000594665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     HK06"
                     /protein_id="HET3115658.1"
                     /translation="MIKNPKLLTKSFLRSFAILGGVGLVIHIAIYLTFPFYYIQLEGE
                     KFNESARVFTEYLKTKTSDEIPSLLQSYSKSLTISAHLKRDIVDKRLPLVHDLDIKDG
                     KLSNYIVMLDMSVSTADGKQVTVQFVHGVDIYKEAKNILLLYLPYTFLVTIAFSFVFS
                     YFYTKRLLNPLFYISEVTSKMQDLDDNIRFDESRKDEVGEVGKQINGMYEHLLKVIHE
                     LESRNEQIVKLQNQKVSFVRGASHELKTPLASLRIILENMQHNIGDYKDHPKYIAKSI
                     NKIDQMSHLLEEVLESSKFQEWTECRETLTVKPVLVDILSRYQELAHSIGVTIENQLT
                     DATRVVMSLRALDKVLTNLISNAIKYSDKNGRVIISEQDGYLSIKNTCAPLSDQELEH
                     LFDIFYHSQIVTDKDESSGLGLYIVNNILESYQMDYSFLPYEHGMEFKISL"
     gene            complement(3387..4040)
                     /gene="rr06"
                     /locus_tag="VQ862_001305"
     CDS             complement(3387..4040)
                     /gene="rr06"
                     /locus_tag="VQ862_001305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001024075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator RR06"
                     /protein_id="HET3115659.1"
                     /translation="MNILVADDEEMIREGIAAFLTEEGYHVIMAKDGQEVLEKFQDLP
                     IHLMVLDLMMPRKSGFEVLKEINQKHDIPVIVLSALGDETTQSQVFDLYADDHVTKPF
                     SLVLLVKRIKALIRRYYVIEDIWRYQDVTVDFTSYKAHYKNEEIDLKPKELLVLKCLI
                     QHKNQVLSREQILEEISKDVADLPCDRVVDVYIRTLRKKLALDCIVTVKNVGYKISL"
     gene            complement(4682..7114)
                     /locus_tag="VQ862_001306"
     CDS             complement(4682..7114)
                     /locus_tag="VQ862_001306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001109706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HET3115660.1"
                     /translation="MNYSKALNECIESAYMVAGHFGARYLESWHLLIAMSNHSYSVAG
                     ATLNDYPYELDRLEEVALELTETDYSQDETFTELPFSRRLQILFDEAEYVASVVHAKV
                     LGTEHVLYAILHDGNALATRILERAGFSYEDKKDQVKIAALRRNLEERAGWTREDLKA
                     LRQRHRTVADKQNSMANMMGMPQTPSGGLEDYTHDLTEQACSGKLEPVIGRDKEISRM
                     IQILSRKTKNNPVLVGDAGVGKTALALGLAQRIASGDVPAEMAKMRVLELDLMNVVAG
                     TRFRGDFEERMNNIIKDIEEDGQVILFIDELHTIMGSGSGIDSTLDAANILKPALARG
                     TLRTVGATTQEEYQKHIEKDAALSRRFAKVTIEEPSVADSMTILQGLKATYEKHHRVQ
                     ITDEAVETAVKMAHRYLTSRHLPDSAIDLLDEAAATVQNKVKYVKADDSDLSPADKAL
                     MDGKWKQAAQLIAKEEEVPVYKDLVTESDILTTLSRLSGIPVQKLTQTDAKKYLNLEA
                     ELHKRVIGQDQAVSSISRAIRRNQSGIRSHKRPIGSFMFLGPTGVGKTELAKALAEVL
                     FDDESALIRFDMSEYMEKFAASRLNGAPPGYVGYEEGGELTEKVRNKPYSVLLFDEVE
                     KAHPDIFNVLLQVLDDGVLTDSKGRKVDFSNTIIIMTSNLGATALRDDKTVGFGAKDI
                     RFDQENMEKRMFEELKKAYRPEFINRIDEKVVFHSLSSDHMQEVVKIMVKPLVASLAE
                     KGIDLKLQASALKLLANQGYDPEMGARPLRRTLQTEVEDKLAELLLKGDLVAGSTLKI
                     GVKAGQLKFDIA"
     gene            complement(7116..7574)
                     /locus_tag="VQ862_001307"
     CDS             complement(7116..7574)
                     /locus_tag="VQ862_001307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001211265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CtsR family transcriptional regulator"
                     /protein_id="HET3115661.1"
                     /translation="MRFKNTSDHIEAYIKAILDQSGIVELQRSQLADTFQVVPSQINY
                     VIKTRFTESRGYLVESKRGGGGYIRIGRIEFSSHHEMLRELLYSIGERVSQEIYEDIL
                     QLLVEQELMTKQEMNLLESVALDRVLGEEAPVVRANMLRQIIQEVDRKGK"
     gene            complement(7693..8421)
                     /locus_tag="VQ862_001308"
     CDS             complement(7693..8421)
                     /locus_tag="VQ862_001308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3115662.1"
                     /translation="MTEIRLEHVSYAYGQERILEDINLQVTSGEVVSILGPSGVGKTT
                     LFNLIAGILEVQSGRIVLDGEENPKGRVSYMLQKDLLLEHKTVLGNIILPLLIQKVDK
                     AEAISRADKILATFQLTAVRDKYPHELSGGMRQRVALLRTYLFGHKLFLLDEAFSALD
                     EMTKMELHAWYLEIHKQLQLTTLIITHSIEEALNLSDRIYILKNRPGQIVSEIKLDWS
                     EDEDKEVQKIAYKRQILAELGLDK"
     gene            complement(8421..9428)
                     /locus_tag="VQ862_001309"
     CDS             complement(8421..9428)
                     /locus_tag="VQ862_001309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HET3115663.1"
                     /translation="MKKTWKVFLTLVTALVAVVLVACGQGTASKDNKEAELKKVDFIL
                     DWTPNTNHTGLYVAKEKGYFKEAGVDVDLKLPPEESSSDLVINGKAPFAVYFQDYMAK
                     KLEKGAGITAVAAIVEHNTSGIISRKSDNVSSPKDLVGKKYGTWNDPTELAMLKTLVE
                     SQGGDFEKVEKVPNNDSNSITPIANGVFDTAWIYYGWDGILAKSQGVDANFMYLKDYV
                     KEFDYYSPVIIANNDYLKDNKEEARKVIQAIKKGYQYAMEHPEEAADILIKNAPELKE
                     KRDFVIESQKYLSKEYASDKEKWGQFDAARWNAFYKWDKENGILKEDLTDKGFTNEFV
                     K"
     gene            complement(9466..10224)
                     /locus_tag="VQ862_001310"
     CDS             complement(9466..10224)
                     /locus_tag="VQ862_001310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009013602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET3115664.1"
                     /translation="MRNLKSILRRHISLLGFLGVLSIWQLAGFLKLLPKFILPTPLEI
                     LQPFVRDREFLWHHSWATLRVALLGLILGVLIACLMAVLMDSLTWLNDLIYPMMVVIQ
                     TIPTIAIAPILVLWLGYGILPKIVLIILTTTFPIIVSILDGFRHCDKDMLTLFSLMRA
                     NPWQILWHFKIPVSLPYFYAGLRVSVSYAFITTVVSEWLGGFEGLGVYMIQSKKLFQY
                     DTMFAIIILVSIISLLGMKLVDISEKYVIKWKRT"
     gene            complement(10187..10477)
                     /locus_tag="VQ862_001311"
     CDS             complement(10187..10477)
                     /locus_tag="VQ862_001311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000647657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine-binding protein"
                     /protein_id="HET3115665.1"
                     /translation="MKASIALQVLPLAQGIDRIAVIDQVIAYLQTQEVTMVVTPFETV
                     LEGEFDELMRILKEALEVAVQEADNVFANVKINVGEILSIDEKLEKYTETTH"
     regulatory      complement(10548..10650)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            complement(10733..12079)
                     /gene="cbpD"
                     /locus_tag="VQ862_001312"
     CDS             complement(10733..12079)
                     /gene="cbpD"
                     /locus_tag="VQ862_001312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline binding-anchored murein hydrolase CbpD"
                     /protein_id="HET3115666.1"
                     /translation="MKILPFIARGTSYYLKMSVKKLVPFLVVGLMLAAGDSVYAYSRG
                     NGSIARGDDYPAYYKNGSQEIDQWRMYSRQCTSFVAFRLSNVNGFEIPAAYGNANEWG
                     HRARREGYRVDNTPTIGSITWSTAGTYGHVAWVSNVMGDQIEIEEYNYGYTESYNKRV
                     IKANTMTGFIHFKDLDSGSVGNSQSSASTGGTHYFKTKSAIKTEPLVSATVIDYYYPG
                     EKVHYDQILEKDGYKWLSYTAYNGSYRYVQLEAVNKNPLGNSVLSSTGGTHYFKIKSA
                     IKTEPLVSATVIDYYYPGEKVHYDQILEKDGYKWLSYTAYNGSRRYIQLEGVTSSQNY
                     QNQSGNISSYGSNNSSTVGWKKINGSWYHFKSNGSKSTGWLKDGSSWYYLKLSGEMQT
                     GWLKENGSWYYLGSSGAMKTGWYQVSGKWYYSYSSGALAINTTVDGYRVNSDGERV"
     gene            complement(12168..12434)
                     /locus_tag="VQ862_001313"
     CDS             complement(12168..12434)
                     /locus_tag="VQ862_001313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001278167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3115667.1"
                     /translation="MSDAFTDVAKMKKIKEEIKAHEGQVVEMTLENGRKRQKNRLGKL
                     IEVYPSLFIVEFGDVEGDKQVNVYVESFTYSDILTEKNLIHYLD"
     gene            complement(12436..13788)
                     /gene="dnaB"
                     /locus_tag="VQ862_001314"
     CDS             complement(12436..13788)
                     /gene="dnaB"
                     /locus_tag="VQ862_001314"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000852490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replicative DNA helicase"
                     /protein_id="HET3115668.1"
                     /translation="MAEVEELRVQPQDILAEQSVLGAIFIDESKLVFVREYIESRDFF
                     KYAHRLIFQAMVDLSDRGDAIDATTVRTILDNQGDLQNIGGLSYLVEIVNSVPTSANA
                     EYYAKIVAEKAMLRRLIAKLTESVNQAYEASQPADEIIAQAEKGLIDVSENANRSGFK
                     NIRDVLNLNFGNLEARSQQTTDITGIATGYRDLDHMTTGLHEEELIILAARPAVGKTA
                     FALNIAQNIGTKLDKTVAIFSLEMGAESLVDRMLAAEGLVESHSIRTGQLTDEEWQKY
                     TIAQGNLANASIYIDDTPGIRITEIRSRSRKLAQETGNLGLILIDYLQLITGTGRENR
                     QQEVSEISRQLKILAKELKVPVIALSQLSRGVEQRQDKRPVLSDIRESGSIEQDADIV
                     AFLYRDDYYERGGEEEEGIPNNKVEVIIEKNRSGARGTVELIFQKEYNKFSSISKREA
                     "
     gene            complement(13832..14284)
                     /gene="rplI"
                     /locus_tag="VQ862_001315"
     CDS             complement(13832..14284)
                     /gene="rplI"
                     /locus_tag="VQ862_001315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L9"
                     /protein_id="HET3115669.1"
                     /translation="MKVIFLADVKGKGKKGEIKEVPTGYAQNFLIKKNLAKEATAQAV
                     GELRGKQKSEEKAHAEMIAEGKAIKAQLEAEETVVEFVEKVGPDGRTFGSITNKKIAE
                     ELQKQFGIKIDKRHIQVQAPIRAVGLIDVPVKIYQDITSVINLRVKEG"
     gene            complement(14281..16254)
                     /locus_tag="VQ862_001316"
     CDS             complement(14281..16254)
                     /locus_tag="VQ862_001316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DHH family phosphoesterase"
                     /protein_id="HET3115670.1"
                     /translation="MKKFYVSPIFPILVGLIAFGVLSTFIIFVNNNLLTVLILFLFVG
                     GYVFLFKKLRVHYTRSDVEQIQYVNHQAEESLTALLEQMPVGVMKLNLSSGEVEWFNP
                     YAELILTKEDGDFDLEAVQTIIKASVGNPSTYAKLGEKRYAVHMDASSGVLYFVDVSR
                     EQAITDELVTSRPVIGIVSVDNYDDLEDATSESDISQINSFVANFISEFSEKYMMFSR
                     RVSMDRFYLFTDYTVLEGLMNDKFSVIDAFREESKQRQLPLTLSMGFSYGDGNHDEIG
                     KVALLNLNLAEVRGGDQVVVKENDETKNPVYFGGGSAASIKRTRTRTRAMMTAISDKI
                     RSVDQVFVVGHKNLDMDALGSAVGMQLFASNVIENSYALYDEEQMSPDIERAVSFIEK
                     EGVTKLLSVKDAMGMVTNRSLLILVDHSKTALTLSKEFYDLFTQTIVIDHHRRDQDFP
                     DNAVITYIESGASSASELVTELIQFQNSKKNRLSRMQASVLMAGMMLDTKNFTSRVTS
                     RTFDVASYLRTRGSDSIAIQEIAATDFEEYREVNELILQGCKLGSDVLIAEAKDTKCY
                     DTVVISKAADAMLAMSGIEASFVLAKNTQGFISISARSRSKLNVQRIMEELGGGGHFN
                     LAAAQIKDVTLSEAGEKLTEIVLNEIKEKEKEE"
     gene            complement(16390..16938)
                     /gene="raiA"
                     /locus_tag="VQ862_001317"
     CDS             complement(16390..16938)
                     /gene="raiA"
                     /locus_tag="VQ862_001317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000599099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated translation inhibitor RaiA"
                     /protein_id="HET3115671.1"
                     /translation="MIKYSIRGENLEVTEAIRDYVVSKLEKIEKYFQPEQELDARINL
                     KVYREKTAKVEVTIPLGSITLRAEDVSQDMYGSIDLVTDKIERQIRKNKTKIERKNKN
                     KVATGQLFTDALVEDSNIVQSKVVRSKQIDLKPMDLEEAILQMDLLGHDFFIYVDVED
                     QTTNVIYRREDGEIGLLEVKES"
     gene            complement(17018..17680)
                     /locus_tag="VQ862_001318"
     CDS             complement(17018..17680)
                     /locus_tag="VQ862_001318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComF family protein"
                     /protein_id="HET3115672.1"
                     /translation="MKCLLCGQTMKTVLTFSSLLLLRNDDSCLCSDCDSTFERIGEEN
                     CPNCMKTELSTKCQDCQLWCKEGVGVSHRAIFTYNQAMKDFFSRYKFDGDFLLRKVFA
                     SFLSEELKKYKEYQFVVIPLSPDRYANRGFNQVEGLVEAAGFEYLDLLEKREERASSS
                     KNRSERLGTELPFFIKSGVTIPKKILLIDDIYTTGATINRVKKLLEEAGAKDVKTFSL
                     VR"
     gene            complement(17677..18975)
                     /locus_tag="VQ862_001319"
     CDS             complement(17677..18975)
                     /locus_tag="VQ862_001319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000867598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HET3115673.1"
                     /translation="MKVNLDYLGRLFTENELTEEERQLAEKLPAMRKEKGKLFCQRCN
                     STILEEWYLPIGAYYCRECLLMKRVRSDQTLYYFPQEDFPKQDVLKWRGQLTPFQEKV
                     SEGLLQAVDKQKPTLVHAVTGAGKTEMIYQVVAKVINAGGAVCLASPRIDVCLELYKR
                     LQQDFSCGIALLHGESEPYFRTPLVVATTHQLLKFYQAFDLLIVDEVDAFPYVDNPML
                     YHAVKNSVKENGLRIFLTATSTNELDKKVRLGELKRLNLPRRFHGNPLIIPKPIWLSD
                     FNRYLDKNRLSPKLKSYIEKQRKTAYPLLIFASEIKKGEQLAEILQEQFPNEKIGFVS
                     SVTEDRLEQVQAFRDGELTILISTTILERGVTFPCVDVFVVEANHRLFTKSSLIQIGG
                     RVGRSMDRPTGDLLFFHDGLNASIKKAIKEIQMMNKEAGL"
     gene            19031..19666
                     /locus_tag="VQ862_001320"
     CDS             19031..19666
                     /locus_tag="VQ862_001320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000395753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YigZ family protein"
                     /protein_id="HET3115674.1"
                     /translation="MEFRTIKEDGQVQEEIKKSRFICHAKRVYSEEEARDFITAIKKE
                     HYKATHNCSAFIIGERSEIKRTSDDGEPSGTAGVPMLGVLENHNLTNVCVVVTRYFGG
                     IKLGAGGLIRAYAGSVALAVKEIGIIEIKEQAGIAIQMSYAQYQEYSNFLKEHDLMEL
                     DTNFTDQVDTMIYVDKEEKETIKAALVEFFNGKVTLTDQGLREVEVPVNLV"
     gene            19951..20871
                     /gene="cysK"
                     /locus_tag="VQ862_001321"
     CDS             19951..20871
                     /gene="cysK"
                     /locus_tag="VQ862_001321"
                     /EC_number="2.5.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000029859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase A"
                     /protein_id="HET3115675.1"
                     /translation="MSIYNNITELIGQTPIVKLNNIVPEGAADVYIKLEAFNPGSSVK
                     DRIALSMIEKAEQDGILKLGSTIVEATSGNTGIGLSWVGAAKGYKVVIVMPETMSVER
                     RKIIQAYGAELVLTPGSEGMKGAIAKAQEIAAERDGFLPLQFDNPANPEVHERTTGAE
                     ILAAFGKDGLDAFVAGVGTGGTISGVSHALKSENSNIQVFAVEADESAILSGEKPGPH
                     KIQGISAGFIPDTLDTKAYDGIVRVTSDDALALGREIGGKEGFLVGISSAAAIYGAIE
                     VAKKLGTGKKVLALAPDNGERYLSTALYEL"
     gene            complement(21068..21412)
                     /locus_tag="VQ862_001322"
     CDS             complement(21068..21412)
                     /locus_tag="VQ862_001322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002202361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET3115676.1"
                     /translation="MIAHIIHQKFNLKVPNYRQEEDWARMGLPITRKEISNRHIKTSQ
                     YYLEPLYNLLRERLLTQPLLHADETSYRVLESDSQLTYYWTFLSGKAEKQGITLYHHV
                     LIDLFISYFNPL"
BASE COUNT         6304 a         4839 c         3564 g         6742 t
ORIGIN      
        1 ccattagcgt ttaggtagta ccatgaacca ttgtattgga gccatcctgt cgccattgaa
       61 ccattagcgt ttaggtagta ccatgaacca ttgttttgga gccatcctgt tgccattgaa
      121 ccattagcgt ttagatagta ccatgaacca ttgttttgga gccatcctgt cgccatagcg
      181 ccattgctgt tgaggtagta ccatgagcca ttgttttgga gccatcctgt cgccattgaa
      241 ccatcagtat tgtagaagta ccacataccg ttttcttgtt tccagcctgt ttttggagta
      301 gatggttgtg ctggtttttc agtttttggc ggttgctgtt gagtcaagcg attatattct
      361 tcttctgatc tacgagcata gtcttcttca gcttgttgtt cagctggttt ttctggtttt
      421 ggagctggat tctctggttt tggagctgga ttctctggtt ttggagctgg tttttctggt
      481 tgaggagccg gcgctggttt tggttgttca gctggttttt ctttaacttt atcttcttct
      541 gctgcttttc gtttagcttc ttcttctgct tttttacgat ctgtcttgat tttttctaac
      601 cttgtagcct cagtttcttc actctcaact ttcgcttttg cttgcttaac tttttcctcg
      661 tttcgaggtt ccttagcttc ctcttttact agttcaagct ccgctttttt aacttccaca
      721 tcggactcag caatttcaag ttcaagcgtt ttgtaagtaa tggttgggta gttacggtaa
      781 tcttcttctt tttgatcctt ggctttcttc ttagcttctt caaccttctt ctcagcttct
      841 gctacctttt tttctagttc tgtcggcttg tttggcttcg ctgtatctga agcttccggt
      901 ttagtggaag agcctgaact tgacgaagaa gatggggcct ttttatattt agacacagct
      961 tcatctagtt ttgatcgact tgttgtaata agtccctgta tttcggtttt tgaggttgat
     1021 tgaactattt tattcaaata ctcgttctta atctcttgca acttgttaac tagatctaca
     1081 gtatctttat gtctatctct ctctaatttt gtatagatct cactcacttt tttttcttta
     1141 tattcactga ccgctgtctt tgccttatct cgttctatat tgatttctcc ttgttctgtc
     1201 tgacttttat ttgccatatt agaaaaagtg gctgcttggg tacttccctc gttctctgtc
     1261 gcatgaacca cactccccat aacaagactg gcaactacta cactagctac tccaatacta
     1321 aatttacgaa ttgaataatg tacttttctt tcgctttttg atgcaaacat gtttatttcc
     1381 ttctatattt tttctttaac cttactatat cacttcaata tgaactgtat ataaatcgaa
     1441 ttttgtattt atctctttat gcttccattt gggattataa cttcatgtaa tagcttttcc
     1501 tcttcagcta ttcgtcgata caaaataact gcataaactg gaaaaactaa aacaaaagtc
     1561 acataagcat gactcaacaa ggtcaagcca atcaactcag gaagaatatt taaaaagtaa
     1621 ttaggatgtt ttactgtcct aaacaagata tgatctacat atttgtgatt attgacaagc
     1681 ataagcttca ctgtccaaat atctcccaac aagtgaatca ccaacatcaa catcagcata
     1741 gaaaaaataa gcaagaccaa accaaccata cccatgccat caaaaattgt cttgtgcacc
     1801 actgcctcaa ccaagcaaga gagataaaaa acaatatgag ccatagttaa tcgttttgta
     1861 ttctcaactc caaattcttt cccgccattg ctaaggattc gtttctcatt ctctatcgaa
     1921 cgctttaaaa aaatcaatcg aataaagaat gttactaaaa taatcgctaa taccatatta
     1981 gtatcctttc ttttatctat gcaaagaata acacacttat gttaacccta tatgaacttt
     2041 aataaaaaac taatctgtct acaagctaat cttaaattcc ataccgtgtt cataagggag
     2101 aaaactatag tccatttgat agctttctaa aatattattc acaatgtaaa gacccaaacc
     2161 ggaactttca tccttatctg tcacgatttg agaatgatag aatatatcaa ataaatgttc
     2221 tagttcttgg tcacttagag gcgcacatgt atttttgata gagagatagc catcttgctc
     2281 ggatatgatt acgcgcccat ttttatctga atatttaatt gcattactaa tcaagtttgt
     2341 caaaacctta tccaatgccc taagactcat gacgaccctg gtagcatctg tcaattgatt
     2401 ttcaattgta acacctattg aatgagctaa ttcttgataa cgtgataaaa tatctactaa
     2461 aactggctta acagtcaagg tctcacgaca ctctgtccac tcttggaatt tagaagactc
     2521 cagtacttct tctaataagt ggctcatctg gtcaatctta tttatactct ttgcaatata
     2581 ttttggatga tctttgtaat ctccaatatt atgctgcata ttctctagga taattctaag
     2641 actggctaaa ggggttttca actcatgtga tgctccacgg acaaaggaaa ccttttgatt
     2701 ttgcaatttt acaatttgct cattacgact ttccaactca tgaataacct tcaacaagtg
     2761 ctcatacata ccattaatct gttttccaac ttcaccaact tcatctttcc tactttcatc
     2821 aaaacgaata ttgtcatcca aatcttgcat tttactagtc acttctgaaa tgtaaaaaag
     2881 aggattgagc aagcgtttag tataaaaata agaaaaaaca aaggaaaaag caattgtaac
     2941 caaaaatgta tatgggagat acaaaagcaa aatattcttt gcttctttgt agatatccac
     3001 cccgtgaaca aattgcactg ttacctgttt accatctgct gtactaacag acatatctaa
     3061 catcacgata taatttgata gctttccatc tttaatatcc aagtcatgca caagagggag
     3121 ccgcttatct acaatatctc ttttaaggtg agcagatatg gtcaaggact ttgaataaga
     3181 ctggagtaag cttggaattt catcagatgt cttagtcttt aaatactccg taaacactct
     3241 tgcgctctca ttaaactttt ccccctccag ttgaatataa taaaaaggaa aggtcaaata
     3301 aatagctata tgaatgacta gaccaacacc acctagaatt gcaaaacttc ttaaaaaaga
     3361 cttggttaat aatttaggat tttttatcat aagctaatct tatacccaac atttttcaca
     3421 gtcacgatac aatctaaagc taattttttg cgaagagtac gaatatagac atcaacgacc
     3481 ctatcacaag gtaaatcagc tacatctttt gaaatttctt ccaatatctg ctctctactt
     3541 aaaacttgat ttttatgctg aatcaaacac tttagtacca gtaattcctt tggtttgaga
     3601 tcaatttctt catttttata atgtgctttg taagaggtaa aatccactgt tacatcctga
     3661 tatcgccaaa tatcctctat gacgtagtaa cgtctgataa gcgccttaat acgcttgaca
     3721 agcagtacca aagaaaaagg ttttgtcaca tgatcatcag catagagatc aaatacctgt
     3781 gactgagtag tttcatctcc cagagcactc aagacgatga caggaatatc gtgcttttga
     3841 ttgatttctt ttaacacttc aaaaccactc ttcctaggca tcattaaatc cagtaccatg
     3901 agatggatag ggagatcttg aaatttttcc aagacctctt gtccatcctt agccataatg
     3961 acatgataac cctcttctgt cagaaatgct gcaattcctt ctctaatcat ttcctcgtca
     4021 tctgcaacta aaatgttcat ctctctccct ttctactacc agaactccat acatctattt
     4081 cctgtatgct atttgaaaat ttcctaccag cctatcatct atgataatgg aatggatttc
     4141 atttatccgc tactttttgt caacaacaac gtcaatacaa gaaaatcatt catcttgcag
     4201 cttatactct tcgaaaatct cttcaaacca cgtcagctct atctacaatc taaaaacagt
     4261 gttttgagca acctgtggct agctgcctag tttgttcttt gattttcatt gaatattagt
     4321 ttgatttttc aaataccagc tagaacggat ttgacatgca aaaaagaaac aggtctcttt
     4381 tgaaagaata aaaatttcag ataagactgc tctttttcta ctacacacgc tctaagacaa
     4441 atacgacgga gggtaataaa catatgaatt ttgtgttgaa tggtgaaaac cacggatcgt
     4501 ttagaagcta taggttttag tttcatactc ttcgaaaatc tcttcaaacc acgtcagctc
     4561 tatctgcaac ctcaaaccag tgttttgagc aacctgcggc tagctgccta gtttgctctt
     4621 tgattttcat tgagtttcac tccactgtga cttatggtca gatgctgata cttttattct
     4681 tttatgcaat atcaaatttt aactggcctg ctttgacacc aatcttaagt gtgctgcctg
     4741 ccactaaatc tcccttaaga agaagttctg ccaacttgtc ctccacttct gtttgcaggg
     4801 ttctgcgaag tgggcgagct cccatctctg ggtcatatcc ttgatttgct aacaatttca
     4861 gagctgaagc ttgtaatttc aagtcaatgc ctttttcagc caaacttgcc actaaaggct
     4921 tgaccataat cttcaccact tcctgcatat ggtcactaga taggctatgg aagaccacct
     4981 tctcatcaat acggttgatg aattccggtc tataagcttt tttcagttct tcaaacatgc
     5041 gtttttccat attttcctgg tcaaaacgaa tatccttagc cccaaaacca acagtcttat
     5101 catcacgaag ggcagtcgca cctaggttcg atgtcataat gataatggta tttgaaaaat
     5161 cgaccttgcg tcccttgcta tctgtcaaaa caccgtcatc cagaacttgc aagagaacat
     5221 taaagatatc tgggtgggcc ttctctacct catcaaagag gagaacggaa tagggtttat
     5281 tgcgaacctt ctctgtcaac tctccacctt cttcgtaacc cacatagcct ggaggagctc
     5341 catttagacg gctggctgcg aatttctcca tatactcact catatcaaag cggataaggg
     5401 ctgattcgtc atcaaagaga acttctgcca aagccttggc caactcggtc ttaccgacac
     5461 ctgtgggtcc taggaacata aaggaaccga tcggacgctt gtgactgcga attcctgact
     5521 gattacggcg aatcgcacga ctaatgcttg aaacagcttg atcttgaccg atgacacgtt
     5581 tatggagttc tgcttcaaga tttagatact tcttagcatc cgtttgagtc agtttttgaa
     5641 ctgggattcc tgacaagcga ctcaaggtgg tcaaaatatc agactctgtc accaagtctt
     5701 tgtagacagg tacttcctct tcttttgcga ttagctgggc tgcctgtttc cacttgccat
     5761 ccatcagggc cttatcagct ggactcaaat ctgaatcgtc tgcttttaca tactttacct
     5821 tattttgcac tgttgctgct gcttcgtcca agaggtcgat agcagagtct ggcaagtgac
     5881 gactggttaa ataacgatga gccatcttaa ccgctgtttc aaccgcttca tctgtgattt
     5941 gtacacggtg atgtttctca taagtcgcct tcaaaccttg taaaatagtc atactatctg
     6001 ccacacttgg ttcttcaatc gtcactttag cgaaacgacg agaaagagcc gcatcttttt
     6061 cgatatgttt ttgatattct tcctgagtgg tggcaccaac cgttctcaaa gttccacgcg
     6121 ccaaggctgg tttcaagata ttggccgcat ccagagtcga atcaatcccg ctaccagaac
     6181 ccatgatggt gtggagttca tcgataaaga ggatgacttg gccatcttct tcaatatcct
     6241 tgatgatatt attcatgcgt tcttcaaagt caccacggaa gcgtgtccct gcaacgacat
     6301 tcatcaaatc aagttctaac acgcgcatct tagccatttc cgcaggcacg tcaccactag
     6361 caatacgctg agcaagacca agcgccagag ctgttttccc gacaccagca tccccaacca
     6421 agacagggtt gttcttagtc ttccggctca agatttgaat catacgtgag atttccttgt
     6481 cccgaccgat gactggttct aacttgccag aacacgcttg ctctgtcaaa tcatgcgtat
     6541 agtcctcgag accaccacta ggagtctgcg gcatgcccat catattggcc atagaatttt
     6601 gcttgtcagc tactgtacga tggcgttggc gtaaagcctt gagatcttca cgagtccagc
     6661 ctgcccgttc ttctaaattt cgacgaagag cagcaatctt gacctgatct ttcttgtctt
     6721 cataagaaaa accagccctc tccaagatac gagtcgccaa ggcattgcca tcatgcaaaa
     6781 tcgcatagag gacgtgctct gtccctagca ccttagcatg gaccactgac gctacatact
     6841 ctgcttcgtc aaaaagaatc tgcaaacgac gggagaacgg caattccgta aaagtttcat
     6901 cctggctata gtccgtttca gtcagttcca aagccacctc ttctaaacgg tccagctcat
     6961 acggataatc atttaaagtt gcccctgcta cactataact gtgattagac atggcaatca
     7021 acaagtgcca agactctaga taacgagctc caaaatgtcc agcaaccatg taggcacttt
     7081 cgatacattc attcaatgct tttgaatagt tcatcttact tcccttttct atctacctct
     7141 tgtatgatct gacgtagcat gtttgctcga acaactggag cttcttctcc taaaacgcga
     7201 tccaaagcta ctgattctag caaattcatc tcctgcttgg tcatcaattc ctgctcaacc
     7261 aaaagctgga gaatatcctc ataaatttct tgactgactc gctcaccaat cgagtaaagc
     7321 agctcccgga gcatttcatg atgactagaa aactcaattc gtcctatacg aatgtagcct
     7381 ccaccaccac gcttactttc aaccaagtag cctctacttt ccgtaaagcg tgtcttgatc
     7441 acgtagttaa tctgactagg aacaacctga aaggtatctg ccaactgact ccgttgcaac
     7501 tccacgatac cagattgatc taaaatcgcc ttgatgtagg cctcaatatg atccgatgta
     7561 tttttaaatc tcataacaaa cccacctctc tctttaaacc ttgaccttgt ttgactatta
     7621 taccgaaatt ttctcatttt taaaagaaaa agggcgctgg taaaggataa tcttcaccaa
     7681 ctccctattt ttctacttat ctaagcctaa ttctgccaag atttgacgtt tgtaggcaat
     7741 cttttggact tccttgtcct catcttcaga ccaatctagt ttaatttctg aaacaatctg
     7801 cccagggcga tttttcaaga tatagatgcg gtcgctgaga ttgagggcct cctcaatact
     7861 atgcgtgatg atcagggttg ttagctgcaa ctgcttgtga atctcaagat accaagcgtg
     7921 gagttccatc tttgtcatct catccaaggc gctaaaggcc tcatctaaga gaaagagctt
     7981 gtgcccaaaa aggtaggtcc ggagtaaggc tacacgctgg cgcatcccac cgctaagttc
     8041 atgaggatac ttgtctctta cagctgtcag ctggaaggtc gcaagaattt tatccgctcg
     8101 ggaaatagct tctgccttat ccaccttttg aatcaagagg ggcagaatga tatttccaag
     8161 caccgtcttg tgctccaaga gcagatcctt ttgcaacata taactcacgc gccccttggg
     8221 attttcttca ccatcaagga caattctccc tgactgaact tctaaaatcc cagcgattag
     8281 attaaagagg gtggtctttc caacaccact tgggcctagg atggaaacca cttcgcctga
     8341 agtcacctgt aggttgatat cctctaaaat cctctcctga ccataggcat aactgacgtg
     8401 ctctagtcta atttctgtca ttatttcaca aattcgttgg tgaagccttt gtctgtcaag
     8461 tcttctttaa ggataccatt ttctttatcc catttataga aagcattcca gcgagctgcg
     8521 tcaaattgac cccatttttc cttgtcgctt gcgtattctt ttgacaagta tttttgagat
     8581 tcgatgacaa agtcacgttt ttccttgagt tcaggtgcat tcttgatgag aatatctgca
     8641 gcttcttctg gatgttccat ggcatattgg tagccttttt tgatggcttg gatgactttg
     8701 cgagcttctt ctttgttatc tttcagatag tcgttgtttg cgatgataac tggtgaatag
     8761 tagtcaaact ccttgacata gtctttcaag tacatgaagt tagcatctac accttgagat
     8821 ttagcaagga taccatccca accgtagtaa atccaagcag tatcaaagac gccattggca
     8881 atcggtgtga ttgagtttga gtcgttattt ggtacttttt caaccttctc aaagtctcca
     8941 ccttgagatt ctaccaaggt tttcaacata gcaagttcag ttgggtcatt ccatgtccca
     9001 tatttcttac caaccaagtc ttttggactg cttacattat cagatttacg agagatgatt
     9061 cctgatgtat tgtgttcaac aatagctgca acggcagtga ttcctgctcc tttttccaat
     9121 ttcttagcca tgtagtcttg gaaatacact gcaaatggtg cctttccgtt gataaccaag
     9181 tcagaagaac tttcttctgg tggcaatttc aaatcaacat ccactccagc ttctttgaaa
     9241 taaccttttt ccttggcaac ataaagccct gtgtggttgg tatttggtgt ccagtctagg
     9301 ataaagtcaa ccttcttaag ttctgcctct ttgttgtctt tagaagcagt tccttgacca
     9361 caggccacaa gcacaacagc tacaagagct gttacaagcg ttaaaaacac tttccatgtt
     9421 ttcttcattt tgatttcctc ttttcttttt caaaaacgct ctattttaag tacgtttcca
     9481 tttaatcaca tatttttcac tgatatcgac cagcttcata cccaaaagac tgataatcga
     9541 caccagaata ataatggcaa acatggtatc atactgaaac agttttttag actgaatcat
     9601 ataaacacca agaccttcaa aacctcccaa ccactcagat accacagttg tgataaaggc
     9661 gtaggagaca ctgaccctca gacctgcata aaagtaaggc aggctaaccg ggattttaaa
     9721 atgccacagg atttgccaag ggtttgctcg catcagacta aacaaagtca gcatatcctt
     9781 gtcacaatgc ctaaaaccgt ccaaaatact aacgatgatg ggaaaggttg ttgttaagat
     9841 aatcaagaca atcttgggca aaatcccata acccagccac aagaccagga taggagctat
     9901 ggcaatggtc ggaatggtct gaatgaccac catcataggg taaatcaggt cattgagcca
     9961 agtcaaacta tccatgagca cagccataag acaggcaatc aaaactccca aaatcagccc
    10021 cagtaaagcc actctcaagg tcgcccagct atggtgccag agaaattctc tgtcacgaac
    10081 aaagggctgg agaatttcaa gaggtgtcgg caggataaac ttggggagaa gtttaagaaa
    10141 acctgctaac tgccagattg acaatactcc gagaaagccc aatagactaa tgtgtcgtct
    10201 cagtatactt ttcaagtttc tcatcaatac ttaaaatctc tcctacattt attttgacat
    10261 tggcaaagac attgtctgcc tcctgcactg ccacttccag cgcttctttt agaatgcgca
    10321 taagctcatc aaactcccct tccaagaccg tttcaaatgg tgtcactacc atcgtcactt
    10381 cttgagtttg cagataagca atgacctgat caataacagc tatccgatca atcccctgtg
    10441 ctaggggtaa aacttgcaag gcaatgcttg ctttcataag aacctcctct tctcgttttc
    10501 cttttaaaaa aaagaaaaac ctttaccata catggaaaag gtgcaaaatt agactaagta
    10561 tcgttccctc cgctggcatt acccagatca ggtgcggtcg aagtttaaca cttcctctca
    10621 gactgtacac agactcccat atattatatg tatatatgat agcgcaaaat aagaaaaatg
    10681 tcaaggaaac tgcttacaga aaagagcagg aaatttctcc tactccaatt ttctatactc
    10741 gttctccatc actgtttact ctgtagccat ccaccgtcgt attaatagct aaggcgcctg
    10801 aagagtaaga ataataccac ttaccagaga cctggtacca gcctgttttc attgcccctg
    10861 aactacccag ataataccac gagccattct cctttaacca tcctgtctgc atttcaccag
    10921 ataatttcaa ataataccag ctagaaccgt ctttcagcca tcctgttgat ttagaaccat
    10981 ttgatttgaa atgataccaa ctaccattta ttttcttcca accgacagtt gaactattat
    11041 tggatccata gctagagata tttcctgatt gattctgata attttgtgaa gaagtcactc
    11101 cctctagctg tatatagcga cgacttccgt tataagccgt ataactcaac cacttatagc
    11161 cgtctttttc aagtatctga tcataatgaa ccttctctcc aggataatag taatcaatca
    11221 cagttgcact aactaggggt tcagttttaa tagcagactt gatcttaaaa taatgagttc
    11281 ctcctgttga agaaagaaca gaattaccta gaggattttt attcacagcc tccaattgaa
    11341 cataacgata gcttccatta taggcagtat aactcaacca cttatagccg tctttttcaa
    11401 gtatctgatc ataatgaacc ttctccccag gataatagta atcaatcaca gttgcactaa
    11461 ctaggggttc agttttaata gcagacttgg tcttaaaata atgagttccg cctgttgaag
    11521 ctgaggattg actattccca acactgccac tatccaaatc tttaaaatga ataaatcctg
    11581 tcatcgtgtt tgcttttata actcgtttat tataggattc tgtataacca tagttatatt
    11641 cctcaatctc aatctgatct cccattacat ttgacaccca ggcaacatga ccataagttc
    11701 ctgcagtaga ccaagtaatg gaaccaatcg tcggtgtatt atctacacga taaccttccc
    11761 gacgagcacg atgtccccat tcattcgcat ttccataagc tgccggaatt tcaaaaccat
    11821 tgacattact caaacgaaag gctacaaaag aagtacactg acgagaatac atgcgccact
    11881 gatcaatctc ctggctccca tttttataat aagcaggata atcatcccca cgcgcaatcg
    11941 atccatttcc tctggaatag gcatagacac tatcaccagc tgctagcatc aatcctacta
    12001 ctaaaaaagg aacaagcttt ttaactgaca tcttcaagta ataacttgtt cctcttgcta
    12061 taaacggtaa aattttcatt cttcctcctt aaaaaataat ataaagcgat gattgccttc
    12121 acctaaatta ttcggagaaa aaagaaaaag tgagaaaatt tctcacttta gtcaagataa
    12181 tgaatcaaat tcttttctgt aagaatatct gagtaagtaa aggattcaac gtaaacatta
    12241 acttgtttat ctccttccac atccccaaac tccacaataa atagggatgg ataaacttca
    12301 attagcttac ccaatctatt tttttggcgc ttacgaccat tctccaaagt catttctacg
    12361 acttgtccct catgtgcctt gatttcttct ttgatttttt tcatcttggc tacatctgta
    12421 aatgcatctg acatcttatg cctccctctt tgagatactt gaaaatttat tgtattcttt
    12481 ttggaaaatc aattccactg ttccacgagc tccactacgg tttttctcga taataacttc
    12541 caccttatta tttgggatac cctcctcttc ttcaccacca cgttcatagt agtcatcgcg
    12601 atagagaaaa gctacgatat cagcgtcctg ctcaatagac ccagattcac gaatatcaga
    12661 caagaccggt ctcttgtcct gacgttgttc tacaccacga gaaagctgac tcagagcgat
    12721 tactggaacc ttcaattcct tggctagtat tttcaactga cgagaaattt cagaaacttc
    12781 ttgttgacga ttttctcgac cagttcccgt gataagttgc aaatagtcta tcaaaatcaa
    12841 accaagattt ccagtttctt gagccaattt acgagaacga gaacgaatct ctgtaatccg
    12901 aatacctggc gtatcatcga tatagatact ggcgttagct agattaccct gagcaatagt
    12961 atatttttgc cactcctcat ctgtcaattg ccctgtacgg atagaatgtg actccaccaa
    13021 gccttctgca gctaacatac ggtctaccaa gctttccgca cccatttcga gtgaaaaaat
    13081 agcaaccgtt ttgtccaact tagtcccaat attctgagcg atattcaagg caaatgctgt
    13141 cttaccaact gctggacgag ctgctaagat aatcaactcc tcctcatgaa gtcctgttgt
    13201 catatgatcc aaatcacgat aacctgtcgc aatacctgta atatcggtcg tttgttgcga
    13261 gcgagcttcc agatttccaa agttgagatt caacacatct cgaatgttct taaacccgct
    13321 tcgatttgca ttttcactga catcaatcaa ccctttttct gcctgagcaa taatttcatc
    13381 agctggttgt gacgcttcgt aagcttggtt gacagactct gtcaacttgg caattaaacg
    13441 acgtagcatt gctttttctg caacaatctt agcataatac tccgcattag cagaagttgg
    13501 cacagaatta acaatctcaa ccaagtaaga caagccacca atattctgta aatcaccttg
    13561 attatcaagg atagtacgaa ccgttgttgc atctatggca tcaccacgat cggataaatc
    13621 gaccatggct tggaaaatca aacgatgggc atacttaaaa aagtcccgag actcaatgta
    13681 ttctcgcaca aaaacaagtt tactctcatc aataaagata gcccctaaaa cggattgctc
    13741 agctaagata tcttgaggtt gtactcgtaa ctcttctact tctgccatca gacttccctt
    13801 ccttttacaa tcttgtcaag aaggtgtaaa cttatccttc tttcacacga agattgatta
    13861 cacttgtgat atcttgatag attttcactg gcacatcaat caaaccaacc gctcgaatcg
    13921 gagcttgtac ttgaatatga cgtttatcaa tcttaattcc aaattgcttt tgcaattctt
    13981 ctgcaatctt cttattggta atagaaccaa aggtacgacc atctggacca actttttcaa
    14041 caaattctac aacagtttct tctgcttcaa gttgtgcttt aattgctttt ccttctgcaa
    14101 tcatctcagc gtgagctttt tcttccgatt tttgtttacc acgaagttca cctacagctt
    14161 gagcagtcgc ttctttggct agattctttt tgataagaaa gttttgcgca taccctgttg
    14221 gtacttcctt aatttcgcct tttttacctt ttcctttaac atctgctaaa aagattactt
    14281 tcattcttct ttctcctttt cctttatttc atttaataca atttctgtca gtttttcacc
    14341 tgcttctgac aaggttacat ctttaatttg agctgctgcc aaattaaagt ggcctccacc
    14401 gcctaactct tccataatcc gttgtacatt cagtttacta cgacttcgag ctgagataga
    14461 gataaatcct tgtgtattct tcgcaagaac aaaactcgct tcaatacctg acatggctaa
    14521 catggcatct gctgccttac taataacaac tgtatcatag catttcgtgt ccttagcctc
    14581 tgctattagt acatctgaac ctaatttaca cccctgtaaa ataagttcat taacctcacg
    14641 atattcttca aaatctgtcg cagcaatttc ctggatagca atactatcac ttccgcgcgt
    14701 tctgagatag ctagcaacat caaatgtccg actagttact cgcgaggtga aatttttagt
    14761 atccaacatc ataccagcca tcaaaacact tgcttgcata cgactcaaac gatttttctt
    14821 agaattctgg aactgaatca attccgttac caactcactg gcactacttg caccactttc
    14881 gatataagta atgactgcat tatctggaaa atcctgatcc cttctatggt ggtcaataac
    14941 aatggtttgg gtaaataaat cataaaattc ttttgataat gttaaggctg tctttgaatg
    15001 gtctacaaga atcaacaaag aacgattggt caccatcccc attgcatcct taacagacaa
    15061 caacttcgta actccttctt tttctatgaa tgaaacagct cgttcaatat ctggagacat
    15121 ttgttcttca tcataaagag catagctatt ttcaatcaca ttgctggcga acaactgcat
    15181 acctacagca gagcccaaag catccatgtc taaatttttg tgaccgacta caaaaacctg
    15241 atctacactc cgaatcttat ctgaaatagc tgtcatcata gcgcgcgtac gagtccgtgt
    15301 acgcttgatt gaagcagcag acccaccacc aaaataaact ggatttttcg tttcgtcgtt
    15361 ttccttaaca accacctggt cgccaccacg tacttcagcc aagttcaaat tgagcaaagc
    15421 aactttccct atctcatcat gatttccatc gccataagaa aatcccatac ttaaagtcaa
    15481 gggcaactgt ctctgtttcg actcttctct gaaagcatca ataacagaaa atttatcatt
    15541 catcaagccc tcaagcaccg tgtagtcagt aaatagataa aatcgatcca tacttacccg
    15601 acgagaaaac atcatgtatt tttctgaaaa ctctgatata aaattagcta caaaactatt
    15661 gatttgacta atatctgact cagaagttgc atcctccaaa tcatcataat tatccacaga
    15721 gacaatccca atcactggtc gacttgttac caattcatct gttatggctt gttccctgga
    15781 tacatctaca aaatacaaaa caccggaaga agcatccata tgaacagcat aacgcttctc
    15841 accaagcttg gcataagtag acggatttcc tactgaagcc ttgataatcg tttgaacagc
    15901 ttctaaatca aaatcaccat cttccttggt caaaatcaat tcagcatagg gattaaacca
    15961 ctcaacctct ccagaagata aattcaattt cataacacct acaggcatct gttccaatag
    16021 agctgtcaaa ctttcttccg cttggtggtt tacatactgt atctgttcta catcactcct
    16081 tgtataatgc actctcagtt tcttaaataa aaaaacatag cctcctacaa aaagaaacaa
    16141 aattaaaacc gtcaacagat tattattaac aaaaataatg aaagtggata agactccaaa
    16201 cgcaatcaat cctactagaa taggaaaaat tggacttaca taaaattttt tcattcaaaa
    16261 cctcttggca cccattatac cataataccc ctcaaaaagc gactttttaa aagtgtaatc
    16321 agtaattcta tcaattataa gaaaaaggta gtttacaatt cagtaaacct acctttacac
    16381 atattgaaat taagattctt taacctctaa caaaccaatt tcgccatcct cacgacgata
    16441 aatcacattg gttgtctgat cttcaacatc cacatagata aagaaatcat gccccaataa
    16501 atccatttgt agaattgctt cttccaaatc cattggtttt aaatcaattt gttttgaacg
    16561 aacaacttta gactggacaa tatttgaatc ttccaccaaa gcatctgtaa ataattgacc
    16621 agttgctacc ttatttttat ttttacgctc gatttttgtt ttatttttac gaatctgacg
    16681 ttcaatttta tcagttacaa ggtcaattga accatacata tcttgagata catcttctgc
    16741 gcggagagta atagatccaa gcggaatcgt tacttccact ttagccgttt tttcacgata
    16801 aacttttaag ttaattcggg catccaactc ttgttctggt tggaagtact tttcgatctt
    16861 ttcgagttta gaaactacat aatcacgaat tgcttctgtt acttctaggt tttcaccacg
    16921 gatactatat ttaatcatat gagtaccttc tttctaaaca tttttgtttt tatgatttta
    16981 ttataacgct ttcattctat ttttgcaaat tttttcctca tcttacaagg gaaaatgttt
    17041 ttacatcctt agcaccggct tcttccaaca gtttcttaac acgatttata gttgctcctg
    17101 tagtatagat atcatctata agtaggattt ttttaggaat agtgactcca cttttaataa
    17161 agaaaggaag ttctgtcccc aagcgctctg aacgattttt agaagaactg gctctctctt
    17221 ctcttttctc taataaatct agatactcaa agcctgctgc ctctaccaag ccctcaacct
    17281 gattaaatcc tctattagca tatctatcag gacttagggg aattacaaca aattgatact
    17341 ctttgtactt tttcaactcc tcacttaaaa atgaagcgaa aacttttctt aacaggaagt
    17401 ctccatcaaa cttataccga ctgaaaaaat ccttcatagc ttgattgtaa gtaaaaatcg
    17461 ctctatgact gactccaact ccttctttac accaaagttg acaatcttga cactttgttg
    17521 acaactctgt tttcatacaa tttggacagt tctcttcccc aattctttca aaagtagaat
    17581 cacagtctga acaaagacaa gagtcatcat tcctcagaag taagagacta ctaaaagtta
    17641 aaacagtctt catagtctgc ccacataaca agcacttcat agaccagcct ccttattcat
    17701 catctgaatt tccttaatcg ccttcttgat tgaagcattt aacccatcat ggaagaaaag
    17761 caaatctcct gtcggtctat ccatgcttcg tccaactcgt ccaccaatct gaatcaaact
    17821 agacttggta aacaaacgat gattggcctc tactacgaaa acatccacac aagggaaggt
    17881 aactccacgc tccaagattg tcgtactgat aagtattgtc agttctccat ctcgaaaagc
    17941 ttgtacttgc tctaatcgat cctctgttac agaagataca aagccaattt tctcatttgg
    18001 aaattgctcc tgtaagattt ctgctaactg ctcccctttc ttaatttctg aagcaaaaat
    18061 gagtaacgga taagctgtct ttctctgctt ctcaatatag gactttaact ttggtgacaa
    18121 acgattcttg tctaagtagc gattaaaatc cgataaccaa attggttttg gaataatcaa
    18181 cggatttcca tgaaaccgtc tcggtaaatt cagtcttttt agttctccta aacggacctt
    18241 tttatctaac tcattggtcg aagtcgctgt taaaaagatt ctcaatccat tctcctttac
    18301 actattcttg acagcgtggt aaagcatggg attatcaaca taaggaaaag catctacttc
    18361 atccactatc agcaaatcaa aagcttgata aaacttcaat aactgatggg ttgttgcaac
    18421 aactagtggt gttcgaaaat aaggttccga ttctccatgt agcaaagcta ttccgcaaga
    18481 aaaatcctgt tgcaggcgct tgtacagctc caaacaaaca tctatgcgag gactagccaa
    18541 acacactgca ccacccgcat tgatcacttt agccactact tgataaatca tttctgtctt
    18601 tccagctcct gttaccgcat gaactaaggt tggcttttgc ttgtctactg cttgaagcag
    18661 tccctctgac accttctctt gaaaaggagt taattggccg cgccatttga gaacatcttg
    18721 cttcggaaaa tcctcctgcg gaaaatagta taaagtttga tcacttctga ctcgcttcat
    18781 cagcaagcac tctcgacaat agtaagcacc gatgggcaaa taccattctt ctagaatagt
    18841 actattacaa cgttgacaga aaagtttccc cttctccttt ctcattgctg gaagtttctc
    18901 cgccaactga cgttcttctt ctgttaattc attctcagta aataaacgac cgagataatc
    18961 taaatttact ttcatacttc tttattcgta aaaactagca ctttagatga ttttttagta
    19021 caattaaatc atggaattta ggacaattaa agaggacggc caagtccaag aagaaatcaa
    19081 aaaatctcgc tttatctgcc atgccaagcg tgtttatagc gaagaagagg ctcgtgactt
    19141 cattactgcc atcaaaaaag aacactacaa agcgacacat aactgctctg cctttattat
    19201 tggagaacgt agtgaaatta aacgtacaag tgatgatggt gagcctagtg gtactgctgg
    19261 tgttcccatg cttggggtac tagaaaatca caatctcacc aatgtctgtg tggtcgtgac
    19321 acgctacttt ggtggtatta aactaggcgc tggaggacta attcgtgctt acgccggcag
    19381 tgtcgcctta gctgtcaaag aaattggtat tattgaaata aaagaacagg ctggcattgc
    19441 tattcaaatg tcttatgctc agtaccaaga gtacagtaac ttccttaaag aacatgatct
    19501 catggagctg gatacaaact ttacagatca agtcgatacg atgatttatg ttgataaaga
    19561 agaaaaagaa actattaaag ctgcacttgt ggagtttttt aatggaaaag tcactttaac
    19621 tgaccaaggt ttacgagagg ttgaagttcc tgtaaactta gtgtaaacaa tgaataatac
    19681 agcgtttcgt tgacattctc acaactactt tagcgagcaa aataaaaaga tgcgtaccaa
    19741 aatatactag aaaatgaagc aattcaaacg aaacctgata tcgttttcct tcacacctat
    19801 ttactagaat taactgaacg caatcacttg aaaattaatg actttgatct atgatatata
    19861 gaaatcctat cgcttcgata ggatttctat attttacaaa tggtatggat agcgttatac
    19921 taaagatatc ttatacaaag aggtattcat atgtctattt ataacaacat tactgaatta
    19981 atcggtcaaa caccgattgt taaacttaac aacatcgtgc cagaaggtgc tgcagacgtc
    20041 tatataaagc ttgaagcatt taatcctggt tcatctgtaa aagaccgtat tgcccttagc
    20101 atgattgaaa aagctgaaca agatggtatt ctgaaacttg gttctactat tgttgaagca
    20161 acaagtggaa acaccggtat tggactttca tgggtaggtg ctgctaaagg gtataaagtc
    20221 gtcatcgtta tgcctgaaac tatgagtgta gaacgacgta aaattatcca agcttatggt
    20281 gctgaactcg tcctaactcc tggtagcgag ggaatgaaag gtgctattgc taaggctcaa
    20341 gaaatcgctg ctgaacgtga tggtttcctt cctcttcaat ttgacaatcc agctaatcca
    20401 gaagtacacg aaagaacaac aggagctgag atactagctg ctttcggtaa agatggatta
    20461 gatgcctttg ttgctggagt aggtactggt ggaacgattt ctggtgtttc tcatgcactc
    20521 aaatcagaaa attctaacat tcaagttttt gcagtagaag cagatgaatc tgctattcta
    20581 tctggtgaaa aacctggtcc tcacaaaatt caaggtatct cagctggatt tattcctgat
    20641 acacttgata ctaaagccta tgatggtatc gttcgtgtaa catcagatga cgctcttgca
    20701 ctcggacgtg aaattggtgg aaaagaaggc ttccttgtag ggatttcctc agctgcagct
    20761 atctacggag ccatcgaggt tgccaaaaaa ttaggtacag gtaaaaaagt ccttgcccta
    20821 gcaccagata acggtgaacg ttatctctct acagcacttt atgaattgta accgtccaat
    20881 aacgaagtct attgaaaaat ctccagacta gagaactcac ggatagttcc taatctggag
    20941 atttcttatt tgcacttttc ttgtacaact ttagtccatg gtaaataggc ctctaaaacc
    21001 tctttgttta cgagagtttc cacgtttgga agacattcta gaagatagga tagatatttc
    21061 tcactattta taatggattg aaataagata tgaacaaatc gattaggaca tgatggtaaa
    21121 gcgtaatccc ttgtttctca gctttcccag acaaaaaagt ccaatagtaa gtcagctgac
    21181 tatcactctc tagcacccta taagaagttt catccgcatg aagtaagggc tgagtcaata
    21241 gtctctctcg caagaggtta taaaggggct ccaaatagta ttgactcgtc ttgatatgcc
    21301 gattagagat ttccttacgt gtgattggta aacccatcct agcccaatct tcttcttggc
    21361 gataattggg taccttcaga ttaaacttct gatggatgat gtgagcgata atagaagctg
    21421 agccaaagct atgcgctaaa ggggcttta
//
LOCUS       DAVBOD010000033        20792 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 640-05
            SAMEA1012484-rid20186543.denovo.033, whole genome shotgun sequence.
ACCESSION   DAVBOD010000033 DAVBOD010000000
VERSION     DAVBOD010000033.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012484
            Sequence Read Archive: ERR059358
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 20792)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20792)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979948.1
            Genome Coverage       :: 595x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:03:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,266
            CDSs (total)                      :: 2,219
            Genes (coding)                    :: 2,091
            CDSs (with protein)               :: 2,091
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 71 of 128
            Pseudo Genes (incomplete)         :: 50 of 128
            Pseudo Genes (internal stop)      :: 33 of 128
            Pseudo Genes (multiple problems)  :: 22 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20792
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012484-rid20186543.denovo.033"
                     /strain="NIG 640-05"
                     /db_xref="taxon:1313"
     gene            complement(124..1803)
                     /locus_tag="VQ862_001323"
     CDS             complement(124..1803)
                     /locus_tag="VQ862_001323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HET3115677.1"
                     /translation="MAYTLKPEEVGVFAIGGLGEIGKNTYGIEYQDEIIIVDAGIKFP
                     EDDLLGIDYVIPDYSYIVDNIDRVKAVLITHGHEDHIGGIPFLLKQANVPIYAGPLAL
                     ALIRGKLEEHGLLRNAKLYEINHNTELTFKNLKATFFRTTHSIPEPLGIVIHTPQGKI
                     ICTGDFKFDFTPVGEPADLHRMAALGEDGVLCLLSDSTNAEVPTFTNSEKVVGQSIMK
                     IIQGIEGRIIFASFASNIFRLQQATEAAVKTGRKIAVFGRSMEKAIVNGIDLGYIKAP
                     KGTFIEPNEIKDYPAGEILILCTGSQGEPMAALSRIANGTHRQVQLQPGDTVIFSSSP
                     IPGNTTSVNKLINIISEAGVEVIHGKVNNIHTSGHGGQQEQKLMLRLIKPKYFMPVHG
                     EYRMQKVHAGLAVDTGVEKDNIFIMSNGDVLALTADSARIAGHFNAQDIYVDGNRIGE
                     IGAAVLKDRRDLSEDGVVLAVATVDFKSQMILSGPDILSRGFVYMRESGDLIRQSQRI
                     LFNAIRIALKNKDASVQSVNGAIVNAIRPFLYENTEREPIIIPMILTPDEE"
     gene            complement(1805..2038)
                     /locus_tag="VQ862_001324"
     CDS             complement(1805..2038)
                     /locus_tag="VQ862_001324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-dependent RNA polymerase auxiliary subunit
                     epsilon family protein"
                     /protein_id="HET3115678.1"
                     /translation="MIYKVFYQETKERSPRRETTRALYLDIDASSELEGRIAARQLVE
                     ENRPEYNIEYIELLSDKLLDYEKETGAFKITEF"
     gene            complement(2844..2996)
                     /gene="cibB"
                     /locus_tag="VQ862_001325"
     CDS             complement(2844..2996)
                     /gene="cibB"
                     /locus_tag="VQ862_001325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000977347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fratricide two-peptide bacteriocin subunit CibB"
                     /protein_id="HET3115679.1"
                     /translation="MMKNLNNYREISNKELQEIKGGFGVGVGIALFMAGYTIGKDLRK
                     KFGKSC"
     gene            complement(2998..3183)
                     /gene="cibA"
                     /locus_tag="VQ862_001326"
     CDS             complement(2998..3183)
                     /gene="cibA"
                     /locus_tag="VQ862_001326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000180803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fratricide two-peptide bacteriocin subunit CibA"
                     /protein_id="HET3115680.1"
                     /translation="MTNFDILDNQFLSLSENELSDIDGGLAPLVIFGVAVSWKAIAGG
                     TALIGSGLAAGYFLGGD"
     gene            3361..4044
                     /gene="tsaB"
                     /locus_tag="VQ862_001327"
     CDS             3361..4044
                     /gene="tsaB"
                     /locus_tag="VQ862_001327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000865689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     dimerization subunit type 1 TsaB"
                     /protein_id="HET3115681.1"
                     /translation="MKVLAFDTSSKALSLAILEDKQILAEMTINIKKNHSITLMPAID
                     FLMASLDWTPKDLDRIVVAEGPGSYTGLRIAVATAKTLAHTLNIELVGMSSLLALVPY
                     QQEGLFVSLMDARRNNVYAGFYENAKPVMPEAHLPFERVIELIKGASQVTFVGEVGPF
                     VEQIQEYLPRTNFKETLPNAANLALWAWDKEADSLHDFVPNYLKRVEAEENWLKNHTE
                     SGESYIKRL"
     gene            4041..4478
                     /gene="rimI"
                     /locus_tag="VQ862_001328"
     CDS             4041..4478
                     /gene="rimI"
                     /locus_tag="VQ862_001328"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000569806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HET3115682.1"
                     /translation="MIEIKRIQKHPDLAQAIYAVMIAVYPVSPWTLEQIQADLSQDQT
                     WYALAYDGAEVIGFLAVQENLFEAEVLQIAVKGAYQSQGIASALFAQLPTDKEIFLEV
                     RQSNQRAQAFYKKEKMAVIAERKAYYHDPVEDAIIMKREIDEG"
     gene            4468..5478
                     /gene="tsaD"
                     /locus_tag="VQ862_001329"
     CDS             4468..5478
                     /gene="tsaD"
                     /locus_tag="VQ862_001329"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002896630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
                     /protein_id="HET3115683.1"
                     /translation="MKDRYILAFETSCDETSVAVLKNDDELLSNVIASQIESHKRFGG
                     VVPEVASRHHVEVITACIEEALAEAGITEEDVTAVAVTYGPGLVGALLVGLSAAKAFA
                     WAHGLPLIPVNHMAGHLMAAQSVEPLEFPLLALLVSGGHTELVYVSEAGDYKIVGETR
                     DDAVGEAYDKVGRVMGLTYPAGREIDDLAHQGQDIYDFPRAMIKEDNLEFSFSGLKSA
                     FINLHHNAEQKGESLSTEDLCASFQAAVMDILMAKTKKALEKYPVKTLVVAGGVAANK
                     GLRERLAAEITDVKVIIPPLRLCGDNAGMIAYASVSEWNKENFAGWDLNAKPSLAFDT
                     ME"
     gene            complement(5518..6824)
                     /locus_tag="VQ862_001330"
                     /pseudo
     CDS             complement(5518..6824)
                     /locus_tag="VQ862_001330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011680908.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            complement(7158..7452)
                     /locus_tag="VQ862_001331"
                     /pseudo
     CDS             complement(7158..7452)
                     /locus_tag="VQ862_001331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(7559..7852)
                     /locus_tag="VQ862_001332"
                     /pseudo
     CDS             complement(7559..7852)
                     /locus_tag="VQ862_001332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            8095..9299
                     /locus_tag="VQ862_001333"
                     /pseudo
     CDS             8095..9299
                     /locus_tag="VQ862_001333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001200043.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
     gene            9292..10168
                     /locus_tag="VQ862_001334"
                     /pseudo
     CDS             9292..10168
                     /locus_tag="VQ862_001334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000375706.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
     gene            10255..11871
                     /locus_tag="VQ862_001335"
     CDS             10255..11871
                     /locus_tag="VQ862_001335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000288036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3115684.1"
                     /translation="MYTIIKSNIKKFSLLTIFIVAGQLLLIYAATINALVLNELIAMN
                     LERFLKLSIYQMIVWCGIIFLDWVVKNYQVEVIQEFNLEIRNRVATDISNSTYQEFHS
                     KSSGTYLSWLNNDVQTLNDQAFKQLFLVIKGISGTIFAVVTLNHYHWSLTVATLFSLM
                     IMLLVPKIFASKMREVSLNLTNQNEAFLKSSETILNGFDVLASLNLLYVLPKKIKEAG
                     ILLKMVIQRKTTVETLAGAISFFLNIFFQISLVFLTGYLAIKGIVKIGTIEAIGALTG
                     VIFTALGELGGQLSSIIGTKPIFLKLYSINPIESNKMNDIEPNEVNRDFPLYEAKNIC
                     YKYGDKEILKNLNFCFQRNEKYLILGESGSGKSTLLKLLNGFLRDYSGELRFCGDDIK
                     KTSYLNMVSNVLYVDQKAYLFEGTIRDNILLEENYTDEEILQSLEQVGLSVKDFPNNI
                     LDYYVGDDGRLLSGGQKQKITLARGLIRNKKIVLIDEGTSAIDRRTSLAIERKILDRE
                     DLTVIIVTHAPHPELKQYFTKIYQFPKDFI"
     gene            11891..12734
                     /locus_tag="VQ862_001336"
                     /pseudo
     CDS             11891..12734
                     /locus_tag="VQ862_001336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813546.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            12802..14303
                     /locus_tag="VQ862_001337"
                     /pseudo
     CDS             12802..14303
                     /locus_tag="VQ862_001337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001819023.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine synthase"
     gene            14315..15064
                     /locus_tag="VQ862_001338"
     CDS             14315..15064
                     /locus_tag="VQ862_001338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000069862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PIG-L family deacetylase"
                     /protein_id="HET3115685.1"
                     /translation="MSDNTKYIFLSPHLDDAIFSCGDYISKLTSEGEIVLVITIFSGY
                     PLSQQLQPSAKQFHKLCNLGKYPIEERKKEDRLACERLQCDFRHLSYYECLYRKDRNG
                     NFLYRHIYSKLKNEDTLKNDIIKELLMHLDDKCVVYCPLSLGDHVDHVFVNSIGRALE
                     FMRYKVIYYEDFPYVSDSSMVSYMGKTKELKIYQEELDEKHYIDRISSILCYKSQILI
                     IWKSVEKLLNNIKELYLRNGAAYSIRFWIKK"
     gene            15077..16249
                     /locus_tag="VQ862_001339"
     CDS             15077..16249
                     /locus_tag="VQ862_001339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001017606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide sugar dehydrogenase"
                     /protein_id="HET3115686.1"
                     /translation="MNIAVIGLGHVGLAYALLFASKYKVVAYDIDSVKINNLKKGTLP
                     SKNEELMKFFCENNLNITFFDTFSEIKNNIDYYIIALPTDYDEKIGSFNTYEIEQTVS
                     KILRVKPNGKIILKSTVPIGFSNKLKRLFDTKNIIFVPEFLREGCSIYDNLYPSRIVV
                     GDETVEGRKIAELFLSISTHSTANIKNVMLVSPTEAEAIKLFSNTFLALRVAFFNELD
                     SFAERRSLNAEVVIKGVCLDPRIGNFYNNPSFGFGGYCLPKDTKQLKKEFIEINAPVI
                     EAIDISNTNRKQFIVKQILERKPKIVGIYKLGMKYNSDNYKESAILSIINELLIVGIK
                     ILVYEPNLNVSIDNVIFEKNFELFIKQSDLIVANRWDRDLEAYKDKVYTRGIWIRD"
     gene            16644..17507
                     /locus_tag="VQ862_001340"
     CDS             16644..17507
                     /locus_tag="VQ862_001340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000572848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE/MutR family transcriptional regulator"
                     /protein_id="HET3115687.1"
                     /translation="MIEKMELGEFYKELRLARKLKQSDVACAGLTASQLSKFELGQSM
                     LSADKLILAIQGINMNFDEFGHKLNNYQESPHMRIGRRVVDCFSHQDIAALEQLLEEV
                     DQEQMAQTYRRLNAIVIKNALHSLDKSYPLTEEDSEFLTTYLYAIESWTWFELYLFCN
                     TMPFLSNQDLIFLSTSLLEKSKEFKELVHNRWYMKSGYLNIISELMERKLFSYIPIFE
                     AELERMLRPYDVFEKVLWQFLKKMQIFLQTKGSNQKEIEHFIQSLQVLENPQLTALFE
                     LRLQQYKELID"
     gene            17793..18026
                     /locus_tag="VQ862_001341"
     CDS             17793..18026
                     /locus_tag="VQ862_001341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000933479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3115688.1"
                     /translation="MLNLQFAETMELTEAELQDVRGGNLVNSMGGGGRSGISGWGVPG
                     IYPGWGNQGMSPNRGAFDWTIDLADGLFGRRRR"
     gene            18048..18725
                     /locus_tag="VQ862_001342"
     CDS             18048..18725
                     /locus_tag="VQ862_001342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET3115689.1"
                     /translation="MKKMKEVKFHLATGLLILTYYLIFNVTSDLDFMVALSDNMYYVF
                     QVLLVLILGTIATIAFVKSEHWKECGRFQFRWSYLGVFLLSFFLLFVWANLTTYIFPR
                     TQNGSTVVEVATSLTGISYFVTRILYTSIIAPVSEEVVCRGLLMTSLSKVNRYYLDVL
                     VSAAIFGAMHVLQYGWITTDFIKYFGMGLIFCMMFRYTRSIYWAIALHASWNSFLLIV
                     TLLVFGY"
     gene            18737..19402
                     /locus_tag="VQ862_001343"
     CDS             18737..19402
                     /locus_tag="VQ862_001343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000720786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET3115690.1"
                     /translation="MKKIISHRYFIIVFLLVIADQKFSVLVLRSDLVAGLSDFAYYLS
                     DMMLNFLVVLFALIAMIWSGKWQKINSRKFKGSYLFYSFLALLAFVAWNFVTFFLFPP
                     TRNEISYQHAAPTFTGATAFLMYFFYPVIAGPIFEDMIYRGLVMTALEKGKKWGLDVL
                     GSAVLFGVSHISNHGWVLTDFVFYMGGGLIFAVLFRMTKSIYWPIGLHIVYNGIGQLL
                     MLL"
     gene            19474..20700
                     /locus_tag="VQ862_001344"
     CDS             19474..20700
                     /locus_tag="VQ862_001344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000862399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HET3115691.1"
                     /translation="MKVFLQNRDFRQLTINQWISTLGDTIFYLAFLNYVADASFAPLA
                     ILLITISETLPQVLQIFLGVLADFQHHRVLKYTVISFTKFLLYSIVSLSLSGQSFSLL
                     LVTFICLINLLSDTLSYFSGAMLTPIFIRIIGQDHLAEAIGFKQSTVSLVKTISNILG
                     GVLLGILSIQFISLLNALTFLIAFLGILFIKTDLLKVEKTISYQEGLSVKSFCQHLLQ
                     SSKLIWNMNKVLLVLFIISTSQAVINVTVPVSTLFLRNQPFLNLQTGQSLALLSTFEL
                     SALIVGSLVSGYLQHTISIKTALYASLVIQLLLLVGFATVRFDWILIFSTLDAFFAGV
                     LSPRLQELVFKQIPEESMGAVQSSISAITVVLPSLFTISLVTIATSFGTLAVSFVLLL
                     FLLVAFVMLLNIRESI"
BASE COUNT         6506 a         3242 c         4208 g         6836 t
ORIGIN      
        1 gctttgaggt tgtagataga actgacgaag tcagctcaaa acacagtttt gaggttgtgg
       61 atagaactga cgaagtcagt aacatatata cggcaaggcg aagctgacgt ggtttgaaga
      121 gtattattct tcatctggtg tgaggatcat cgggatgatg atcggttcac gttcggtatt
      181 ttcatagagg aaggggcgaa tagcgttgac aatggcacca ttgacagatt gcacgctagc
      241 atccttattt ttcagtgcga tacgaatggc attgaagagg atacgctggc tttggcgaat
      301 caagtcgcca gactctctca tgtagacaaa gcctcggctg aggatgtctg gaccagatag
      361 aatcatctgc gatttgaagt caacagttgc gactgccaga acgacaccgt cttcagatag
      421 atcgcgacga tctttgagga cagctgcgcc aatttcaccg atacgatttc catcgacata
      481 gatatcttgg gcgttgaaat gacctgcgat acgagctgag tcagcagtaa gggcaagcac
      541 atcgccattg ctcatgataa agatattgtc cttctcaaca ccagtatcca ctgctagtcc
      601 agcgtggact ttttgcatgc ggtattcacc gtggacaggc atgaagtatt ttggcttaat
      661 caagcggagc atgagttttt gctcttgctg accaccgtgt ccagatgtat ggatattgtt
      721 cactttaccg tggataactt cgacaccagc ttcagaaata atgttaatca gcttgttgac
      781 gctagtagtg tttccaggga tgggactaga agagaagata acggtatcgc ctggttggag
      841 ttgtacctga cggtgggttc cgttggcgat acgagagagg gctgccatag gttcaccttg
      901 actacctgta cagaggatca gaatctcacc tgcaggatag tctttgattt catttggctc
      961 aataaaggtt cccttaggag ctttgatgta gccaagatcg attccgttga caatggcctt
     1021 ttccatagag cgaccaaaga ccgcaatctt gcgcccagtc ttaacagcag cttccgttgc
     1081 ttgttggaga cggaagatat ttgaggcgaa ggatgcaaag atgatacgtc cctcgatacc
     1141 ttggataatc ttcatgatgg actggccgac aaccttttca gagttggtaa aggttggaac
     1201 ctcagcattg gtcgagtcag agagcaagca aagcactcca tcttcaccta gggctgccat
     1261 acggtgcaag tccgcaggtt ctccaactgg agtaaagtcg aacttaaagt cacctgtaca
     1321 gatgattttc ccttgaggag tatggatgac aattcccaaa ggttctggaa tagagtgagt
     1381 cgttctaaag aaagttgcct tgagattttt aaaggtcaac tcggtgttgt ggttgatttc
     1441 gtaaagtttg gcgttgcgca agaggccgtg ttcttcgagt ttcccacgga tcaaagccaa
     1501 ggcaagcggt ccagcataaa tagggacatt tgcttgcttg agtaggaacg gaatcccacc
     1561 aatgtggtcc tcgtgtccgt gtgtgattaa aacagccttg acgcggtcga tattgtctac
     1621 gatgtaagag tagtcaggaa tgacatagtc gataccaagc aagtcatctt ctgggaattt
     1681 aatcccagca tcgacgatga taatctcgtc ttggtattca attccgtaag tgtttttccc
     1741 gatttctcct agaccaccga tggcaaaaac gccgacttct tcaggtttaa gagtgtaggc
     1801 catattagaa ctccgtaatt ttgaaggcgc cagtttcttt ttcgtaatcg agcaatttgt
     1861 cagacaagag ttcgatatat tcgatattgt actctgggcg attttcttcg acaagttggc
     1921 gagcagcgat acgaccctca agttctgagc tggcatcgat gtctaggtaa agcgcgcgtg
     1981 ttgtttcacg acgtgggcta cgttcttttg tttcttgata aaaaactttg taaatcatat
     2041 agttcctttc tatttacagg tcagcttatt ccaaactttt agcagagatt tgcttgattt
     2101 cattccattt tgtgtctaga ttgaccttga ttcgttacaa ttatttcaat tataccacaa
     2161 aatgaaaaat tagtaaaaga cggaaacgag aaagttaggg gacgatttct ttggtaagcg
     2221 tttgcaaaaa caaagaaaat gtattatgtt gataacggaa gtgaaattta ttgcttgtca
     2281 taattccata tagattttaa gtcaaggagg ttgccctatg tataacttat ttgcttttgc
     2341 tatcggagtt cgtttgctag cttttatcgt ttttgttgct tgcgtttatg gaggaaatct
     2401 tctatttgcc aaactggaac gatgacaaac caagttcttg aggaaaatta cctttgtgac
     2461 tctctactcg ctttttctcc tcctcgtgac ctatgtcgtt tggtttgtat tttactttgg
     2521 attgccctgc ttatgctggg gttttttgtt tggggatgta gagatagtag atttacgaca
     2581 cgaaaattcc accccatcta tcaagatgag gtggtctttg catttttcta acatgacatg
     2641 acaatggaat tttcaaagct tattattttt atgggagtca ttgttctgct caaaaataga
     2701 gttgaagcat aaaaataaaa caatacaaac agataaatcg aatggtaaag ggatagtagt
     2761 aatgttcaaa tcattgagaa tgctgagcaa actgtaagag atgaagacaa taaaatttat
     2821 ccttctaaaa atgtgtttct tatctagcat gacttaccaa actttttacg aaggtctttt
     2881 ccaatggtat aacctgccat aaataaagcg ataccaacac ctacaccaaa gccacccttg
     2941 atttcttgca attccttatt agaaatttca cgatagttgt tcaaattttt catcatatta
     3001 atctcctcct aaaaaataac cagctgccaa accagaacct ataagtgctg ttccacctgc
     3061 aatagctttc caagatactg ctactccaaa gataaccaag ggagcgagac cgccatcaat
     3121 atctgataat tcattttcag ataaggataa aaattgattg tcaagaatgt caaaatttgt
     3181 cattgaattt tcctcctttt ttcttgttca cttttatatt cggaaaagaa aaggaaaagt
     3241 gagcattttt ttaaattatt tttagttaag tgagggcact cttgtctggg ggcaaagaaa
     3301 attcccatgt gccagctttt gtagtataat agtaagcaga caaaaagata ggaatgtgtt
     3361 atgaaagtat tagcttttga tacgtccagc aaggctcttt ctctcgctat tttagaggat
     3421 aagcagattc ttgccgagat gacgattaat attaagaaaa atcacagtat taccctcatg
     3481 cctgccatcg attttttgat ggcaagtttg gactggacac ccaaggattt ggaccgaatc
     3541 gtggtggctg aagggccagg tagctacaca ggcttgcgaa ttgcggtagc cactgccaag
     3601 actttggctc atactctgaa catcgagtta gttggtatgt ctagcctctt ggctctggta
     3661 ccctaccaac aagaaggctt gttcgtctct ttgatggatg cgcgtcgcaa caatgtttat
     3721 gcaggatttt atgaaaatgc taaacccgtc atgccagaag ctcacttacc ctttgagcga
     3781 gtgattgagt taatcaaggg tgctagtcag gttacctttg tcggagaagt tggccccttt
     3841 gttgagcaga ttcaagaata cttgccaagg actaatttca aagaaacctt gccaaatgca
     3901 gctaatctag ctctatgggc ctgggacaag gaagcagact ccttgcatga ttttgtgccg
     3961 aactacctca agcgtgtcga agctgaggaa aactggctca agaatcacac cgagtctggc
     4021 gagtcttaca ttaaacgctt atgatagaaa tcaaacgaat ccaaaaacat cctgacttgg
     4081 ctcaagccat ctacgctgtt atgatagctg tttacccagt cagtccttgg acgctggaac
     4141 aaatccaagc agacctgtcc caagaccaga cttggtatgc tttggcttat gatggggcag
     4201 aagtgattgg atttctagct gtgcaggaga atctttttga agcagaagtc ctgcaaatcg
     4261 ctgtcaaagg agcttatcag agtcagggga ttgcgtcagc cttgtttgct caattgccga
     4321 cagacaagga aattttcctc gaagtcagac agtcaaatca acgagcgcaa gcattttaca
     4381 agaaagaaaa gatggcagtt atcgctgagc gaaaggccta ctaccatgac ccagtcgagg
     4441 acgccattat catgaagaga gaaatagatg aaggatagat atattttagc atttgagaca
     4501 tcctgtgatg agaccagtgt cgccgtcttg aaaaacgacg atgagctctt gtccaatgtc
     4561 attgctagtc aaattgagag tcacaaacgt tttggtggcg tagtgcccga agtagccagt
     4621 cgtcaccatg tcgaggtcat tacagcctgt atcgaggagg cattggcaga agcagggatt
     4681 accgaagagg acgtgacagc tgttgcggtt acctacggac caggcttggt cggagccttg
     4741 ctagttggtt tgtcagctgc caaggccttt gcttgggctc acggacttcc actgattcct
     4801 gttaatcaca tggctgggca cctcatggca gctcagagtg tggagccttt ggagtttccc
     4861 ttgctagccc ttttagtcag tggtgggcac acagagttgg tctatgtttc tgaggctggc
     4921 gattacaaga ttgttgggga gacacgagac gatgcagttg gggaggctta tgacaaggtc
     4981 ggtcgtgtca tgggcttgac ctatcctgca ggtcgtgaga ttgacgatct ggctcatcag
     5041 gggcaggata tttatgattt cccccgtgcc atgattaagg aagataatct ggagttctcc
     5101 ttctcaggtt tgaaatctgc ctttatcaat cttcatcaca atgccgagca aaagggagaa
     5161 agcctgtcta cagaagattt gtgtgcttcc ttccaagcag cagttatgga cattctcatg
     5221 gcaaaaacta agaaggcttt ggagaaatat cctgttaaaa ccctagttgt ggcaggtggt
     5281 gtggcagcca ataaaggtct cagagaacgc ctagcagccg aaatcacaga tgtcaaggtt
     5341 atcatccccc ctctgcgact ctgcggagac aatgcaggta tgattgccta tgccagcgtc
     5401 agcgagtgga acaaagaaaa cttcgcaggc tgggacctca atgccaaacc aagtcttgcc
     5461 tttgatacca tggaataaag agtggctctt tgtcaagtgt agtgggtagg cgaaaagcta
     5521 caatctggag agtacgaaat tcgtactctc ttttttgatg ttcaaagtca tcaaaatccg
     5581 ttttttaaaa ttgttaaagt tccggaaacc aaaggctttg cgcttgataa ccttaatcaa
     5641 attattggtc gcttcaagtt tagcgttgga ataaggcagc ttaagtgcgt tgataatctt
     5701 atctctatcc cttaaaaaag tccaaaagac cgtttgaaaa agcggatgaa ccgttggcag
     5761 ttcttgctca atcaatccaa agaaatggtc ggcattcttc tcttgaaaat gaaagagcag
     5821 gagttgatag agttcgtagt gaacctgtaa tccctcagag taagaaagca gcttatctcg
     5881 tacttcccga tgggttaagt gcattcgaaa cgtgggctga tagaatcgtt tctgacagag
     5941 cttgaagcta tcctggtgta gtaaatcagt ccagtggact gatttagccc gagcctagaa
     6001 acgaaaaagc gagggttcca aaagcgcttg agcgcccgat actccaagga ttttcggtca
     6061 aattggttca tgatttggat tcgtactcgg ttcatagctc ggctcagatg ttggacaatg
     6121 tggaagcggt caagaacaat cttcgccttt ggaaagagtt gcttagcgag ccgataataa
     6181 gggctgtaca tgtccatggt gatgacctcg accagctccc gaacctctct ctgatagcgt
     6241 tggaaatggt ttcgaatcac cgcatgagtt cgtccgtcta aaattgcgag gatggatttg
     6301 gactcaaaat cttgggcaat gaagctcatt ttgctctttt tgaagctata ctcatcccaa
     6361 ctcataactt ttggcaactt ggtccaatcg gtttcaaact taaattccct cagttttcgg
     6421 atgacggtgg aagttgagcc cgccaatctg tgggcaatct cagtcataga ctgcttttca
     6481 aggaggagct gagcgatttt ttgtctcacc atgttggaaa tctggcaatt tttcttgaca
     6541 atggatgttt gagaaacgac caccttaagg caattcttgc actgaaagcg gcgctttttg
     6601 agatgcagta ccgtgggtaa accctgacag tcgagaagcg gaattttaga ggctttctgg
     6661 aagtcgtatt tgatcatctt cccttgacaa tgaggacaag gaggagcggg ggaatccaac
     6721 tttgcctgaa cgactagatg ggtttggtat ttcagaacag acaagatttt gatatttttg
     6781 tcttccaatc cgagcaaatc tgtggtattc ttaagttgtt ccatatgaac cctttctaat
     6841 gagttggtta gacgcttttc attataggtc atatggggct ttttttctac aagaaacgac
     6901 cctataattc ctggggtggg attacccact acagaaatta tagagccaaa gcattccaaa
     6961 gtcttgtctg actctggaat gttttctgtt cacagttgtt ttgtaactgc ctaataagta
     7021 accgcgctat aacgaggtat ctaccgagat tgtcaattct ccagtatact gttataaaaa
     7081 acaaaactgg aggatttttt tatgtccccc ccatcgtccc atcgactgtt ccgtagctgc
     7141 ccaataacgg agtataatca gctgaaacaa gaataggaca aaagtgcctc aagaaaagca
     7201 tcgtaagttg acaatattat tctgagatgt ttttgatgta agcccatatt ttctcaatgg
     7261 gattatactc gggtgaatag gtaggaagtg gtaacagtct atgccctgct ccttacacat
     7321 gttcattctg tgaaaccttg cattgtccat aatgataagg gatggtgtat ctaaagtagg
     7381 tagtaagaat ttttggaagc aagcttcgaa aaagtcactc gtcatcgtat ctttataggt
     7441 catcggagcc atagtatatt gaaacaaaaa agggcattag tacttctata acagtatcgc
     7501 aatctctggt gtgcgttgtc tcgatcttaa ttcaaataat tatatcttct tccagagaga
     7561 ctaactgcct gctcaaggct cgatcatatt cgagataaaa ataggtctca acccctgtct
     7621 cataaatata aataggagtc aggtagctta agtgattcaa ttctttaagg aaccgattta
     7681 ctttttctgg gtcttgttcg cagtaggtac ggctcttttt tagactatat cccatagcct
     7741 ttagagcgta atgaatagtt gttggaggac agttgaattc agcagctatt tcagtcaaat
     7801 aagcatcggg atgagtttca atatagattt ttaatttatc tctatcaatt ttttcaatta
     7861 atagtggaag tttttttgaa gttagtgtat tgaaacgttt ttatacagtg ctaaaatttg
     7921 aagtgtagtg cagatgtatt tgtaatagta ttatagcaat tctttggaga aggtcgagac
     7981 aagataaaat aggtatcttt gagatataag catgatttac tataaaatta ttgagttatt
     8041 cataaaaatt tctctatcaa atatcataat gcgtcgttta aggagatggt tacaatgcaa
     8101 tatagttgtg gaaaaataaa tattaatatc cctgatggat atggagacat taaggatata
     8161 gtgttttcgg ctcatattat agttaggtat aataatggac attgtggagg tatagatccg
     8221 catataattg gactttgtaa aaagcagatc agaaggatgt ctctatatcc tattttgata
     8281 atcgtatcta gagattcaaa ggttattgat gattataaaa atttagatat tgcctatgtt
     8341 gattgtactc aatgttcaaa taattttgaa actgccttac acgttaaaaa tattttaaaa
     8401 ttattaaaaa tccaacttat acactgtcat ggctactcaa ctaattattt tttatatatg
     8461 ttaaaaaaac ttgacaagaa tggatttgga aaggttaaga cagtgataac atgccatgga
     8521 tgggttgaat ataacttaaa aaagaaattc ttgacttatt ttgatttttg gacatattct
     8581 atgggagatg cttttatttg tgtatctgaa actatgaaaa aaagattgga gagtataata
     8641 aaaaaataag aagatagttg caataaataa cggaattaat gtatcaaata gcgatttaga
     8701 tgtagtaggt gttcaagact ttaaaaaaga attttgtatt ccaaataaca aaaaatcatt
     8761 tgttatgttg gaaggttgga tccagaaaaa aggccggata gattccttga atttgcagaa
     8821 aaattatttt tagtcagaga agatgtgatt tttattatgg ctggaaatgg tagtatgtgg
     8881 gctgctttga aagaaaaaat ttgctatttg aaatgtagag ataatttcag gttacttggt
     8941 gaaatctatc cagtactata gtttaccaaa tatcggattt attgtatatt ccttctgata
     9001 cagaaggaat atctatgtgt gttttagagt caatgtcaca aggaactccg gttttagcta
     9061 gtaatgttgg cgggttaagt gaaattattg aacatagggt tgatggattt ttatttgaga
     9121 aggaagatgt tgagggagtg tgtgcttgtg ctaatttttt actcaatgat tctgagtatt
     9181 tgaaatatgt aggtgagaat agtaaatcaa aaataagaaa acatttttct gtgcaaaaaa
     9241 tgtttgtaga aaccatgaga gtatatgatg aattattaga gaagagtagt catggatagg
     9301 aatatagatc aagaattagt aagtattata ataccaacac ataataggta tgaatctctg
     9361 attagagctg tgaaaagttg tttacatcaa agttataaaa atatcgaagt tataattatt
     9421 gatgataatt atagtaatgt aaatttaaga aataaaatta tccatcaatt tggctatacc
     9481 aatcatagaa ttaagttaat tttaagtaat gaagatttag gtgcaactaa tgccagaaac
     9541 ataggtatca aaaattctag aggtaagtat atatcatttt tagacgatga tgatgaatat
     9601 atgccagatc gaattttaaa gttgatggct tgttttaaaa agagtagaat gaagaattta
     9661 gctttagttt atagttatgg aataataatt tatccaaatg gtacacgaga agaggagaag
     9721 accgattttg ttggaaatcc cttgtttgtt caaatggttc acaatatagc aggtacgtca
     9781 ttttggttgt gtaaaaaaga ggtgctagaa ttaattaatg gttttgagaa aatagattca
     9841 catcaggacg gtgttgtttt attaaaacta cttgctcaag gataccaaat tgatatagtg
     9901 cgagaattct tggtgaatta ctacgctcac agtaaagaaa acggtatcac tggagtgaca
     9961 caaaaaacaa ttaatgcaga tgaagaatat tataattact gtaggaaata ttttaattta
    10021 ttgagtttca acgagagaat attggttaca aagaaatatt attctttaaa cataaagcgg
    10081 ttactattta ataggagaca aatgcaaggc tttaaaagta atcaagaagg caagagaaga
    10141 aaaaattttt aacgaatttc ttttttaaaa tatatgttat tatatcattt tggttttttc
    10201 tattgtatat atgacaacta tgttcaatta aaatttagaa agtgagaaac tattgtgtat
    10261 actattataa aatcaaatat aaaaaaattt agtttattaa cgatatttat tgttgctggt
    10321 caattattgc taatttatgc agcaactatt aatgctctgg tgttgaatga attaattgcg
    10381 atgaatttag agcggttttt gaaattgtca atctaccaaa tgattgtctg gtgtgggata
    10441 atattccttg actgggtagt gaaaaattat caggttgaag tgatccaaga gtttaatcta
    10501 gagattcgaa atagagttgc cacagacatc tctaactcta cctatcaaga atttcatagt
    10561 aaatcatcag gaacatatct ttcgtggcta aataatgatg ttcagacttt aaatgatcag
    10621 gcttttaaac aacttttttt agtaataaaa ggaatttctg gtactatatt tgcagttgtg
    10681 actcttaatc actatcattg gtcattgact gtagccacct tgttttcatt aatgattatg
    10741 ctacttgtac caaaaatctt tgcatcgaaa atgcgagaag ttagtctaaa tttaactaac
    10801 caaaatgaag cttttttaaa atctagtgag actatattga atggatttga tgtgttagcg
    10861 tccttgaatc ttttatatgt attgcctaag aaaattaaag aagcaggaat tttattaaag
    10921 atggttatac aaagaaagac aactgtagaa acgttagcag gcgctattag cttctttctc
    10981 aatatttttt ttcagatatc tctcgttttt ttaacaggct atcttgcaat aaaaggaata
    11041 gtgaaaattg gtactattga agcaatagga gcactaacag gtgttatttt tacagcgcta
    11101 ggtgaattag gaggtcaatt atcctctatt attggtacga agcctatttt tttaaaattg
    11161 tattcaatta atccaattga gtcaaataaa atgaatgata tcgaaccaaa tgaggtgaat
    11221 agagattttc cgttatatga agcaaaaaat atttgctata agtatggaga taaagaaata
    11281 ttaaaaaact taaatttttg ttttcaacgt aatgaaaagt atttaatttt aggtgaaagt
    11341 ggaagcggga aatctacatt attaaaatta ttgaatggct ttttgagaga ttatagtgga
    11401 gaattgcgat tctgcgggga tgatataaaa aaaacctcct atttaaatat ggtttcgaat
    11461 gttctatatg tagatcaaaa agcttatttg tttgaaggta cgattagaga taatatttta
    11521 ttggaagaaa attatactga tgaagaaata ctacagtctt tagagcaagt tggtttgagt
    11581 gtaaaagatt ttcctaataa cattttagat tattatgttg gtgatgatgg gagattactg
    11641 tcaggagggc agaaacaaaa aattacttta gctagagggc taattagaaa taagaaaata
    11701 gtattaattg acgagggaac ttctgctatc gataggagaa cttcgttagc gattgaacgt
    11761 aagatattag atagagagga tttgactgtc attattgtta cccatgctcc gcatccggaa
    11821 cttaaacaat attttactaa gatatatcaa tttccaaagg attttattta agaatatagg
    11881 ggagggaaac atgagattct attgtgaagc ttatgaggta attactgaag agaaaaaagt
    11941 atactttaat gatattgagt tagaagttaa gtattcctct gtcgaagaat tgtttataat
    12001 atgtgagaaa ttattagata agaaaaaagt atcatttttt tatgtatatg agaaaccctt
    12061 aaggtatctg ttatttgact atatatttct actagttcta gctaaaaaaa tatcccaatc
    12121 ttagatggag tttccaataa gcaagttgat ccaacgttgc tgcatcactt ttctttggaa
    12181 attgaaaaga attttatcga tttttgctat aaaaatatgg atctcatcct aaaaactcaa
    12241 agtatatctt tgtgtcatag agaagagctt attattgtag atgtttcaga tgactctaaa
    12301 tttggtgttt tttacaagcg ttttagaaca ctggttgata aaaataacgg aaaatatgtt
    12361 tgtgtttata atttcagtcg tgtttcagat atactgcaaa actggaaaaa ttattgcaat
    12421 cgaaaatttt cggttacgtt tactgaaagc caatttgaat tatttaagct tttatataat
    12481 caaaaaaatt ttaaaacaat ttcgttgcta tttggaaaaa aattgttgct ggaggaatta
    12541 tctattatag cgatcttact aatatagaat acttttgtat tttttggtgg gatagtatgt
    12601 ttgggaaaga ttctattgga aaatacgtat atgtagaaga gattagtaga tgtcattttt
    12661 tagatagaaa ttattctttt tgttatggtt tacaagatta taaaagtaaa cttattaaat
    12721 attttttaga atagttaatc tattcgagag agataaagaa atatggaaaa tactttattg
    12781 aatatcacag gaagcttcga tatggaaact aggaatctaa ttagttattc tttaactgat
    12841 atctttgaaa cagataaaat aagaattgaa cttcttggag aaatttatta taaaaatata
    12901 aagttggaat tgcatgaatt cgctggattg tataagattt atggaattag cttaataaag
    12961 aatattaccg gaatgttttt aattataatt tttgatacga agacaaaaga attaaaaatt
    13021 tttcaagata taacgacttc atactttaat ttatactata ctgtttatgg aggtgtgttc
    13081 tatatatagt acatctttaa agaaagtgat gaagttatct catgttcccg ttaccttaaa
    13141 taacaaaaaa atacaagaat ttatgagaaa tggatttatt ttagattcaa atactttagt
    13201 aaccgaaatt aataaattag aatatttctc ttacatttct gtaaataata ctcttcgtat
    13261 atgtggtatt gattataatg attcaaacaa ttttactaaa gaacaagtat taaagaattg
    13321 ggactctatg ctacgtgaat ctatattaag agtgtatagt gaagcaggag aggctaatat
    13381 tacactatca tctggttttg attcaaatta tatattatat acattagcga attatacgaa
    13441 ttcttcaatt aatgcatttt gcataggagg agaaaaagga attaatgaga ttcctgaagt
    13501 aactaaaatt gcaaaatttt atggtataaa tttattagtt gatactgtaa tgagcccaag
    13561 atttagaata ttttcccgat atagtatgga gattggaagg aagtctcttt gaatgtggtg
    13621 tcatactgca gtactattta ggcaggttgt tgttccaaaa agggaacaca agtattcttt
    13681 gtggcgagtc agcggatgaa ataatgactt ttaagtatca ttctgtgaac tacaatcaat
    13741 tttgtaatga taaacagaag tcagtatatt ttagttattc cgactatcca ttttatgtta
    13801 caaattcaat tgttttaaag aaaaatagcc tacttttgca tagttttggc attcatccta
    13861 gatatccata taaaatgtct gagattgttg aaatgtctaa aaaaatatca gatctaaacg
    13921 ataaaaaaga atttcacaaa aagaactgtg agttgaggtt tcaagatagt gttcttgata
    13981 acataaatag tgtcccgggt acaactcatt tatttagttg tttaaatatt caaacattag
    14041 taaaaattat tttatatatt tttcgataca acagttgtat gaaaatattt aattttagag
    14101 ataaagagct tatctttttt aataagattg taaatgggct gatacaaaat attgaggaga
    14161 atttagagga tgatattgaa aggatattga aatatttata tatatgttta tttaacgaaa
    14221 tattcattat taagaataag gtgaattttt ttgatgatgt ggaatttaat cagacactta
    14281 gtgagttttt agataaattg tagagggaat ggttatgagt gacaatacta agtatatctt
    14341 tttatctcca catttagatg acgcaatttt ttcctgtggt gattatattt caaaattaac
    14401 ttcagaagga gaaattgtac ttgttattac tatattttct ggttaccctt tgagccaaca
    14461 gctacagccc tctgctaagc aatttcataa gttgtgtaac cttgggaaat atccgattga
    14521 agaaaggaag aaagaagaca ggttagcttg tgaacgtcta caatgtgatt ttagacactt
    14581 atcgtactat gaatgtctct ataggaaaga tagaaatggc aattttctat accgtcatat
    14641 ctatagtaaa ttaaaaaatg aggacacatt aaagaatgat atcataaaag agctgttaat
    14701 gcatttagac gacaaatgtg tcgtatattg tccgctttca cttggtgacc atgttgatca
    14761 tgtttttgtg aatagtattg gaagggcgct tgaatttatg cgttataaag taatatatta
    14821 tgaggacttc ccatatgtaa gtgatagtag tatggttagt tatatgggaa aaactaaaga
    14881 attaaaaatc tatcaagagg aacttgatga aaaacattat attgatagaa tatcatcaat
    14941 attgtgctat aaatctcaga ttttgataat ctggaaatca gttgaaaaac ttttaaacaa
    15001 tattaaagag ttgtatttaa ggaatggggc agcttattct attagatttt ggattaagaa
    15061 ataaggaagt agttttatga atatagcagt aattggtttg gggcatgttg ggctggccta
    15121 cgcgttacta tttgcatcta aatataaagt tgttgcatat gatatagatt ctgtaaaaat
    15181 aaataattta aaaaagggca ctcttccatc taaaaatgaa gagcttatga agtttttttg
    15241 cgagaataac ttaaatatta ctttttttga tacattttct gaaattaaaa ataatattga
    15301 ttattatatt attgcgcttc cgacagatta tgatgagaaa attggtagtt ttaatacata
    15361 tgaaatcgaa caaacggtat cgaagattct gagggtaaaa cctaatggaa agattatttt
    15421 aaagtcaaca gttccgatcg gcttttcaaa caaattaaaa aggctgtttg atacaaaaaa
    15481 tatcattttt gtccctgaat ttttgagaga aggttgttct atatatgata atttatatcc
    15541 aagtcgcata gttgttggag atgagacagt tgaaggaaga aaaattgcag agttgttcct
    15601 ttcgattagt actcatagta ctgccaatat taaaaatgtt atgttagttt ctcctactga
    15661 agcagaagca attaagcttt tttctaacac attcttagct ctccgtgttg ctttttttaa
    15721 tgaactagat tcttttgctg agaggagaag tttaaatgct gaagttgtaa taaaaggtgt
    15781 ttgtttagat ccaagaattg gaaattttta taataatcct tcttttggat ttggaggata
    15841 ttgtcttccc aaagatacta aacaattaaa aaaagaattt atagaaataa atgccccagt
    15901 gatagaagcg attgatattt caaacacaaa tagaaaacag ttcatagtta aacaaatatt
    15961 ggaacgaaag ccaaagatag taggaatata taaattgggg atgaaatata attcagataa
    16021 ttacaaagag tcagctattt taagtataat taatgaacta ttgattgtcg gtataaaaat
    16081 tttagtatat gaaccaaatt taaacgttag tatagataac gtaatttttg aaaagaattt
    16141 tgaactattt ataaaacaaa gtgatctaat tgttgcaaat agatgggata gggaccttga
    16201 agcttataaa gataaagttt acacaagggg gatctggata agagattaac tattgatatt
    16261 aaaaaggcaa taatttataa aatttgtaca aaaaaatgtt aaattttcac attttcatag
    16321 tatactgttt aatagaaagt aggttctttg taaccgctcc attataaaat cctttcactc
    16381 ttccggtata ctattaggaa aaacataact ggaggatatt ttgagctcac acctcatcgt
    16441 tccagtggct gttccccaag ctcgtgtact gcccaaaaaa gttagacatt ctatttagaa
    16501 cgaggattga gttctgtatt gtacaaggct cggtcctttt agagtcagct taaggctggc
    16561 tttttcaatc accaaagtgt cagaatgttt tgacaaatga acacaaataa tgatataata
    16621 tgcaaaagct aggaggtggt aggatgattg aaaaaatgga actgggggaa ttttacaagg
    16681 aattgcgctt ggcgagaaag ctcaagcagt cagatgtggc ttgtgctgga ctaacagcct
    16741 ctcagttgtc caagtttgaa ctaggacagt ctatgctgtc tgcagacaag ctgatcctag
    16801 ccatccaagg gatcaatatg aattttgatg agtttgggca caaactcaac aactatcaag
    16861 aatctccaca tatgcgaatt ggtagaaggg ttgtggattg cttttcccat caggatatag
    16921 ctgctttaga gcagctattg gaggaagtcg atcaagaaca gatggcgcag acctatcgtc
    16981 gtttgaatgc cattgtgatt aaaaatgcac tccattcctt agataaaagc tacccgctaa
    17041 cagaggagga tagcgagttt ttgactacct acctctacgc tattgagtct tggacctggt
    17101 ttgaactcta tcttttttgc aatactatgc ccttcttgag caatcaagat ctgatctttt
    17161 tatcaacctc cttactcgaa aaatccaagg aatttaaaga gttagtacac aatcgatggt
    17221 atatgaaaag tggttatctt aatatcatct cagaacttat ggagcgcaag ctattttctt
    17281 atattccaat ctttgaagct gagctggagc gcatgctccg tccatacgat gtttttgaaa
    17341 aagtattgtg gcagttttta aagaaaatgc agatttttct tcaaaccaaa ggaagcaatc
    17401 aaaaagagat tgaacacttt atccaatctc tgcaagtatt agaaaatcca caattgacag
    17461 ccctttttga attgcgtttg cagcaataca aagagcttat cgattagtta gaaatgggaa
    17521 aaagataata atatcagcaa cgatcgtcaa taatgttaaa acttgtttct tcatattact
    17581 tccctcctca ttagtaataa ctttattata ccagggaaat aatcaaatct accaaaatcg
    17641 caaatctgaa atttctataa gaaaaaatat caaatatgcg attttctaaa ataagccaat
    17701 ttccgtgtta tactgtcctt gtaaaacatt tgaagcaaat cctaggtcgc agaagtggtt
    17761 tacaaatgaa gataattgaa ggagtgtaaa agatgttaaa tttacaattt gcagaaacaa
    17821 tggaattgac agaagctgag ttgcaagatg ttagaggagg caacctcgta aattctatgg
    17881 gaggtggtgg aagaagtggt atatctggtt ggggcgtccc aggaatttac cctggttggg
    17941 gcaatcaagg gatgagtcct aatcgtggag cttttgattg gactatagat ttagcagatg
    18001 gattgtttgg ccgccgtaga agataggctc ttataggaga taataggatg aagaaaatga
    18061 aagaagtgaa atttcaccta gcaactggct tgttgatttt gacttattac ctcattttta
    18121 atgtcacatc agacttagat tttatggttg ctttgtctga taatatgtac tatgtgttcc
    18181 aagttttatt ggtacttatt ctgggaacta tagctacaat tgcttttgtc aaaagtgaac
    18241 attggaaaga gtgtggtcgt ttccagtttc gttggtctta cctgggtgtt ttccttcttt
    18301 cttttttctt attgttcgtg tgggcaaatc taacaaccta tatctttcct cgtacccaga
    18361 atggaagtac agtcgtagaa gtagccacca gtttaacagg aattagctat tttgttacgc
    18421 gaatacttta tactagtatt atcgcacctg tatcagaaga ggttgtttgt cgtggtcttt
    18481 tgatgacaag tttatctaaa gttaatagat actatcttga tgttcttgtt tccgctgcca
    18541 tatttggcgc tatgcatgtt ttgcagtatg gttggataac gacagatttc ataaagtatt
    18601 ttggaatggg cttgatattt tgtatgatgt ttcgctacac ccgatccatc tattgggcta
    18661 tagctctgca tgcttcatgg aatagcttct tactcattgt tactttattg gtatttggat
    18721 attagaaagg tgatatatga aaaagataat ctcacaccgc tactttatta tagtttttct
    18781 actagttatt gctgaccaga agttcagtgt tttagtttta cgcagcgacc ttgttgctgg
    18841 gctatctgac tttgcctatt atctgtcgga tatgatgttg aattttcttg tggttttatt
    18901 tgctcttatt gctatgattt ggtcggggaa atggcagaaa atcaatagta gaaagtttaa
    18961 aggatcctat cttttctatt ccttcctagc tctgcttgct tttgttgctt ggaattttgt
    19021 cacctttttt cttttcccac ctactcgaaa tgaaatttct tatcaacatg ctgctcctac
    19081 ttttacagga gctacggcat ttttgatgta ttttttttat cctgtgattg caggtcccat
    19141 ttttgaagac atgatttatc gtggattagt gatgactgct ctggaaaaag gaaagaaatg
    19201 ggggctagat gtacttggtt ccgctgtttt atttggggtc tcgcacatta gtaatcacgg
    19261 ttgggtcttg acagactttg tcttctatat gggtggaggt cttatatttg cagtcttatt
    19321 tagaatgaca aagtcaattt attggcctat tggactgcat atagtctaca atggtattgg
    19381 tcagcttttg atgttactgt aattttggtt gttagtagta tcgcggtcta ttcttgggga
    19441 aagattccca tttgaattta aaaaggagtt gtaatgaaag tatttcttca aaatagagat
    19501 tttaggcaat taactatcaa ccagtggatt tcaacgcttg gggatacgat tttttatctg
    19561 gccttcctga attatgtggc agatgcgtct tttgcccctt tggcgatttt acttatcacg
    19621 atttcagaaa cccttcccca agttctacaa atctttctgg gagttttggc ggattttcaa
    19681 catcatcgtg tcttgaaata cacagtcatt agttttacaa aatttttgct ttactctata
    19741 gtgtccctat cgctttcagg gcagtctttt tccttgttgc tagtaacctt tatttgtctg
    19801 attaacctct tgtctgacac attgagttat ttttcaggcg ccatgctcac tccgattttc
    19861 attagaatta ttgggcaaga tcatctggca gaagctattg gatttaaaca gtcaactgtt
    19921 agtttagtga aaacaatcag taatatccta ggaggagtct tactaggtat tctatccatc
    19981 cagtttattt ccttactgaa cgctcttacc tttttaatcg catttttagg tatcctcttc
    20041 ataaaaactg acctcttgaa agtagaaaaa acgattagct atcaagaagg actctctgta
    20101 aaatcctttt gccagcattt gctccaatca tcgaaattga tatggaatat gaataaggtg
    20161 ctcttggttt tgtttattat ctctactagt caagcagtga taaatgttac agttcctgtc
    20221 tctactctat ttttgaggaa tcaacccttt ttgaatttac aaacaggtca atctcttgcc
    20281 ttgctatcca cttttgaact gtcagccctg attgtcggaa gccttgtaag tggctatctg
    20341 caacatacca tttccataaa aacagctctc tatgcctcac ttgtcatcca gttgcttctt
    20401 ctagtaggat ttgccacagt tcgttttgac tggattctca tctttagtac cttggatgcc
    20461 tttttcgcag gtgttctctc tcctagattg caagaactcg tctttaaaca aatacctgag
    20521 gagtcaatgg gagcagttca atcttctatc agtgccatta cggttgtttt acctagctta
    20581 tttacaatat ctttggtaac cattgctact agctttggaa ctctggcagt tagctttgtt
    20641 ttattgctat ttcttctagt tgcctttgtt atgcttctga atattcgtga aagtatttag
    20701 tggagaattt ctataatata tgtttgagac tggattgcca gtctttttat gatggtcaaa
    20761 atcaacagac ttttttctct tttctgaatg tg
//
LOCUS       DAVBOD010000034        20686 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 640-05
            SAMEA1012484-rid20186543.denovo.034, whole genome shotgun sequence.
ACCESSION   DAVBOD010000034 DAVBOD010000000
VERSION     DAVBOD010000034.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012484
            Sequence Read Archive: ERR059358
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 20686)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20686)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979948.1
            Genome Coverage       :: 595x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:03:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,266
            CDSs (total)                      :: 2,219
            Genes (coding)                    :: 2,091
            CDSs (with protein)               :: 2,091
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 71 of 128
            Pseudo Genes (incomplete)         :: 50 of 128
            Pseudo Genes (internal stop)      :: 33 of 128
            Pseudo Genes (multiple problems)  :: 22 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20686
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012484-rid20186543.denovo.034"
                     /strain="NIG 640-05"
                     /db_xref="taxon:1313"
     gene            171..2153
                     /locus_tag="VQ862_001345"
     CDS             171..2153
                     /locus_tag="VQ862_001345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HET3115692.1"
                     /translation="MKSSKLFALAGVTLLAATTLAACSGSGSSTKGEKTFSYIYETDP
                     DNLNYLTTAKAATANITSNVVDGLLENDRYGNFVPSMAEDWSVSKDGLTYTYTIRKDA
                     KWYTSEGEEYAAVKAQDFVTGLKYAADKKSDALYLVQESIKGLDAYVKGEIKDFSQVG
                     IKALDEQTVQYTLNKPESFWNSKTTMGVLAPVNEEFLNSKGDDFAKATDPSSLLYNGP
                     YLLKSIVTKSSVEFAKNPNYWDKDNVHVDKVKLSFWDGQDTSKPAENFKDGSLTAARL
                     YPTSASFAELEKSMKDNIVYTQQDSITYLVGTNIDRQSYKYTSKTSDEQKASTKKALL
                     NKDFRQAIAFGFDRTAYASQLNGQTGASKILRNLFVPPTFVQADGKNFGDMVKEKLVT
                     YGDEWKDVNLADSQDGLYNPEKAKAEFAKAKSALQAEGVQFPIHLDMPVDQTATTKVQ
                     RVQSMKQSLEATLGADNVIIDIQQLQKDEVNNITYFAENAAGEDWDLSDNVGWGPDFA
                     DPSTYLDIIKPSVGESTKTYLGFDSGEDNVAAKKVGLYDYEKLVTEAGDEATDVAKRY
                     DKYAAAQAWLTDSALIIPTTSRTGRPILSKMVPFTIPFALSGNKGTSEPVLYKYLELQ
                     DKAVTVDEYQKAQEKWMKEKEESNKKAQEDLAKHVK"
     gene            2454..7757
                     /locus_tag="VQ862_001346"
     CDS             2454..7757
                     /locus_tag="VQ862_001346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001032503.1"
                     /note="The YSIRK form of extended signal peptide directs
                     nascent proteins to the cross-wall site, while signal
                     peptides lacking YSIRK direct proteins instead to the cell
                     pole. A large fraction of YSIRK proteins are surface
                     proteins anchored by sortase-mediated processing of a
                     C-terminal LPXTG motif; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-type signal peptide-containing protein"
                     /protein_id="HET3115693.1"
                     /translation="MNKGLFEKRCKYSIRKFSLGVASVMIGAAFFGTSPVLADSVQSG
                     STANLPADLATALATAKENDGRDFEAPKVGEDQGSPEVTDGPKTEEELLALEKEKPAE
                     EKPKEDKPAAAKPETPKTVTPEWKTVEKKEQKGTVTIREEKGVRYNQLSSTAQNDNAG
                     KPALFEKKGLTVDANGNATVDLTFKDDSEKGKSRFGVFLKFKDTNNNVFVGYDKDGWF
                     WEYKSPTTSTWYRGSRVAAPETGSTNRLSITLKSDGQLNASNNDVNLFDTVTLPAAVN
                     DHLKNEKKILLKAGSYDDERTVVSVKTDNQEGVKTEDTPAEKETGPEVDDSKVTYDTI
                     QSKVLKAVIDQAFPRVKEYTLNGHTLPGQVQQFNQVFINNHRITPEVTYKKINETTAE
                     YLMKLRDDAHLINAEMTVRLQVVDNQLHFDVTKIVNHNQVTPGQKIDDERKLLSSISF
                     LGNALVSVSSDQTGAKFDGATMSNNTHVSGDDHIDVTNPMKDLAKGYMYGFVSTDKLA
                     AGVWSNSQNSYGGGSNDWTRLTAYKETVGNANYVGIHSSEWQWEKAYKGIVFPEYTKE
                     LPSAKVVITEDANADKNVDWQDGAIAYRSIMNNPQGWEKVKDITAYRIAMNFGSQAQN
                     PFLMTLDGIKKINLHTDGLGQGVLLKGYGSEGHDSGHLNYADIGKRIGGVEDFKTLIE
                     KAKKYGAHLGIHVNASETYPESKYFNEKILRKNPDGSYSYGWNWLDQGINIDAAYDLA
                     HGRLARWEDLKKKLGDGLDFIYVDVWGNGQSGDNGAWATHVLAKEINKQGWRFAIEWG
                     HGGEYDSTFHHWAADLTYGGYTNKGINSAITRFIRNHQKDAWVGDYRSYGGAANYPLL
                     GGYSMKDFEGWQGRSDYNGYVTNLFAHDVMTKYFQHFTVSKWENGTPVTMTDNGSTYK
                     WTPEMRVELVDADNNKVVVTRKSNDVNSPQYRERTVTLNGRVIQDGSAYLTPWNWDAN
                     GKKLSTEKEKMYYFNTQAGTTTWTLPSDWAKSKVYLYKLTDQGKTEEQELTVKDGKIT
                     LDLLANQPYVLYRSKQTNPEMSWSEGMHIYDQGFNSGTLKHWTISGDASKAEIVKSQG
                     ANDMLRIQGNKEKVSLTQKLTGLKPNTKYAVYVGVDNRSNAKAIITVNTGEKEVTTYT
                     NKSLALNYVKAYAHNTRRDNATVDDTSYFQNMYAFFTTGSDVSNVTLTLSREAGDEAT
                     YFDEIRTFENNSSMYGDKHDTGQGTFKQDFENVAQGIFPFVVGGVEGVEDNRTHLSEK
                     HDPYTQRGWNGKKVDDVIEGNWSLKTNGLVSRRNLVYQTIPQNFRFEAGKTYRVTFEY
                     EAGSDNTYAFVVGKGEFQSGRRGTQASNLEMHELPNTWTDSKKAKKATFLVTGAETGD
                     TWVGIYSTGNASNTRGDSGGNANFRGYNDFMMDNLQIEEITLTGNMLTENALKNYLPT
                     VAMTNYTKESMDALKEAVFNLSQADDDISVEEARAEIAKIETLKNALVQKKTALVADD
                     FASLTAPAQAQEGLANAFDGNLSSLWHTSWNGGDVGKPATMVLKEPTEITGLRYVPRG
                     SGSNGNLRDVKLVVTDESGKEHTFTATDWPDNNKPKDIDFGKTIKAKKIVLTGTKTYG
                     DGGDKYQSAAELIFTRPQVAETPLDLSGYEAALTKAQKLTDKDNQEEVASVQASMKYA
                     TDNHLLTERMVEYFADYLNQLKDSATKPDAPTVEKPEFKLSSLASEQGKTPDYKQEIA
                     RPETPEQILPATGESQSDTALFLAGVSLALSALFVVKTKKD"
     gene            complement(7924..10083)
                     /locus_tag="VQ862_001347"
     CDS             complement(7924..10083)
                     /locus_tag="VQ862_001347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001040003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBP1A family penicillin-binding protein"
                     /protein_id="HET3115694.1"
                     /translation="MNKPTILRLIKYLSISFLSLVIAAIVLGGGVFFYYVSKAPSLSE
                     SKLVATTSSKIYDNKNQLIADLGSERRVNAQANDIPTDLVKAIVSIEDHRFFDHRGID
                     TIRILGAFLRNLQSNSLQGGSTLTQQLIKLTYFSTSTSDQTISRKAQEAWLAIQLEQK
                     ATKQEILTYYINKVYMSNGNYGMQTAAQNYYGKDLNNLSLPQLALLAGMPQAPNQYDP
                     YSHPEAAQDRRNLVLSEMKNQGYISAEQYEKAVNTPITDGLQSLKSASNYPAYMDNYL
                     KEVINQVEEETGYNLLTTGMDVYTNVDQEAQKHLWDIYNTDEYVAYPDDELQVASTIV
                     DVSNGKVIAQLGARHQSSNVSFGINQAVETNRDWGSTMKPITDYAPALEYGVYDSTAT
                     IVHDEPYNYPGTNTPVYNWDRGYFGNITLQYALQQSRNVPAVETLNKVGLNRAKTFLN
                     GLGIDYPSIHYSNAISSNTTESDKKYGASSEKMAAAYAAFANGGTYYKPMYIHKVVFS
                     DGSEKEFSNVGTRAMKETTAYMMTDMMKTVLSYGTGRNAYLAWLPQAGKTGTSNYTDE
                     EIENHIKTSQFVAPDELFAGYTRKYSMAVWTGYSNRLTPLVGNGLTVAAKVYRSMMTY
                     LSEGSNPEDWNIPEGLYRNGEFVFKNGARSTWSSPAPQQPPSTESSSSSSDSSTSQSS
                     STTPSTNNSTTTNPNNNTQQSNTTPDQQNQNPQSAQP"
     gene            complement(10080..10676)
                     /gene="recU"
                     /locus_tag="VQ862_001348"
     CDS             complement(10080..10676)
                     /gene="recU"
                     /locus_tag="VQ862_001348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RecU"
                     /protein_id="HET3115695.1"
                     /translation="MVNYPHKVSSQKRQTSLSQPKNFANRGMSFEKMINATNDYYLSQ
                     GLAVIHKKPTPIQIVQVDYPQRSRAKIVEAYFRQASTTDYSGVYNGYYIDFEVKETKQ
                     KRAIPMKNFHPHQIQHMEQVLAQQGICFVLLHFSSQQETYLLPAFDLIRFYHQDKRQK
                     SMPLEYIREYGYEIKAGAFPQIPYLNVIKEHLLGGKTR"
     gene            10742..11269
                     /locus_tag="VQ862_001349"
     CDS             10742..11269
                     /locus_tag="VQ862_001349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000179549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1273 domain-containing protein"
                     /protein_id="HET3115696.1"
                     /translation="MATALVLGYSAFDLGLFSDKDPRLKLIKKAIRKDLEAMAADGVS
                     WLVFTGSLGFEYWVLEVAQEMKTEYGFQLATIFAFETHGENWNEGNQMKLSRFKQVDF
                     VKYAYPRYEHKGQLRDYQQFLLENTTSSYLFYDEENETKLAYFYQKMKNQEDYFIKRL
                     TFDELNELAENFSEN"
     gene            11339..11668
                     /gene="gpsB"
                     /locus_tag="VQ862_001350"
     CDS             11339..11668
                     /gene="gpsB"
                     /locus_tag="VQ862_001350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000146522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division regulator GpsB"
                     /protein_id="HET3115697.1"
                     /translation="MASIIFSAKDIFEQEFGREVRGYNKVEVDEFLDDVIKDYETYAA
                     LVKSLRQEIADLKEELTRKPKPSPVQAEPLEAAITSSMTNFDILKRLNRLEKEVFGKQ
                     ILDNSDF"
     gene            11689..12069
                     /gene="rnpB"
                     /locus_tag="VQ862_001351"
     ncRNA           11689..12069
                     /ncRNA_class="RNase_P_RNA"
                     /gene="rnpB"
                     /locus_tag="VQ862_001351"
                     /product="RNase P RNA component class B"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00011"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00011"
     gene            12154..13311
                     /locus_tag="VQ862_001352"
     CDS             12154..13311
                     /locus_tag="VQ862_001352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent RNA methyltransferase"
                     /protein_id="HET3115698.1"
                     /translation="MKKEFNLIATVAAGLEAVVGREVRELGYDCQVENGRVRFQGDVR
                     AIIETNLWLRAADRIKIIVGTFPAKTFEELFQGVFALDWENYLPLGARFPISKAKCVK
                     SKLHNEPSVQAISKKAVVKKLQKHYARPEGVPLMENGPEFKIEVSILKDVATVMIDTT
                     GSSLFKRGYRTEKGGAPIKENMAAAILQLSNWYPDKPLIDPTCGSGTFCIEAVMIARK
                     MAPGLRRSFAFEEWNWISDRLIQEVRTEAAKKVERELELDIMGCDIDARMVEIAKANA
                     QAAGVAGDITFKQMRVQDLRSDKINGVIISNPPYGERLSDDAGVTKLYAEMGQVFAPL
                     KTWSKFILTSDEAFESKYGSQADKKRKLYNGTLKVDLYQYFGQRVKRQEVK"
     gene            13324..14718
                     /gene="mapZ"
                     /locus_tag="VQ862_001353"
     CDS             13324..14718
                     /gene="mapZ"
                     /locus_tag="VQ862_001353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000039255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mid-cell-anchored protein MapZ"
                     /protein_id="HET3115699.1"
                     /translation="MSKKRRNRHKKEGQEPQFDFDEAKELTVGQAIRKNEEVEAGVLP
                     EDSILDKYVKQHRDEIEADKFATRQYKKEEFVETQSLDDLIQEMREAVEKSEASSEEV
                     PSSEDILLPLPLDDEEQGLDPLLLDDENPTEMTEEVEEEQNLSRLDQEDSEKKSKKGF
                     ILTVLALVSVIICVSAYYVYRQVARSTKEIETSQSTTANQSDVDDFNTLYDAFYTDSN
                     KTALKNSQFDKLSQLKTLLDKLEGSREHTLAKSKYDSLATQIKAIQDVNAQFEKPAIV
                     DGVLDTNAKAKSDAKFTDIKTGNTELDKVLDKAISLGKSQQTSTSSSSSSQTSSSSSS
                     QASSNTTSEPKPSSSNETRSSRSEVNMGLSSAGVAVQRSASRVAYNQSAIDDSNNSAW
                     DFADGVLEQILATSRSRGYITGDQYILERVNIVNGNGYYNLYKPDGTYLFTLNCKTGY
                     FVGNGAGHADDLDY"
     gene            14794..16218
                     /gene="gndA"
                     /locus_tag="VQ862_001354"
     CDS             14794..16218
                     /gene="gndA"
                     /locus_tag="VQ862_001354"
                     /EC_number="1.1.1.44"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004185725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent phosphogluconate dehydrogenase"
                     /protein_id="HET3115700.1"
                     /translation="MTKANFGVVGMAVMGRNLALNIESRGYTVAIYNRSKEKTEDVIA
                     CHPEKNFVPSYDVESFVNSIEKPRRIMLMVQAGPGTDATIQALLPHLDKGDILIDGGN
                     TFYKDTIRRNEELANSGINFIGTGVSGGEKGALEGPSIMPGGQKEAYELVADVLEEIS
                     AKAPEDGKPCVTYIGPDGAGHYVKMVHNGIEYGDMQLIAESYDLMQHLLGLSAEDMAE
                     IFTEWNKGELDSYLIEITADILSRKDDEGQDGPIVDYILDAAGNKGTGKWTSQSSLDL
                     GVPLSLITESVFARYISTYKEERVHASKVLPKPAAFNFEGDKAELIEKIRQALYFSKI
                     ISYAQGFAQLRVASKENNWNLPFADIASIWRDGCIIRSRFLQKITDAYNRDADLANLL
                     LDEYFLDVTAKYQQAVRDIVALAVQAGVPVPTFSAAITYFDSYRSADLPANLIQAQRD
                     YFGAHTYQRKDKEGTFHYSWYDEK"
     gene            16230..16919
                     /locus_tag="VQ862_001355"
     CDS             16230..16919
                     /locus_tag="VQ862_001355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000518023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET3115701.1"
                     /translation="MGKRILLLEKERNLAHFLSLELQKEQYRVDLVEEGQKALSMALQ
                     TDYDLMLLNVNLGDMMAQDFAEKLSRTKPASVIMILDHWEDLQEELEVVQRFAVSYIY
                     KPVLIENLVARISAIFRGRDFIDQHCSLMKVPRTYRNLRIDVEHHTVYRGEEMIALTR
                     REYDLLATLMGSKKVLTREQLLESVWKYESATETNIVDVYIRYLRSKLDVKGQKSYIK
                     TVRGVGYTMQE"
     gene            17017..18036
                     /gene="cbpC"
                     /locus_tag="VQ862_001356"
     CDS             17017..18036
                     /gene="cbpC"
                     /locus_tag="VQ862_001356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000771060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein CbpC"
                     /protein_id="HET3115702.1"
                     /translation="MKLLKKMMQVLLAVFFFGLLATNTVFANTTGGRFVDKDNRKYYV
                     KDDHKAIYWHKIDGKTYYFGDIGEMVVGWQYLEIPGTGYRDNLFDNQPVNEIGLQEKW
                     YYFGQDGALLEQTDKQVLEAKTSENTGKVYGEQYPLSAEKRTYYFDNNYAVKTGWIYE
                     DGNWYYLNKLGNFGDDSYNPLPISEVAKGWTQDFHVTIDIDRSKPAPWYYLDPETGIM
                     RTGWQYLGNNWYYLRSSGAMATGWYQEGTTWYYLDQPNGDMKTGWQNLGNKWYYLRSS
                     GAMATGWYQDGSTWYYLNAGNGDMKTGWFQVNGNWYYAYSSGALAVNTTVDGYSVNYN
                     GEWVR"
     gene            complement(18154..19386)
                     /locus_tag="VQ862_001357"
     CDS             complement(18154..19386)
                     /locus_tag="VQ862_001357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000765682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HET3115703.1"
                     /translation="MKLFWTNNIYRQLLLNSCFSSFGDSIFYLAIINYVAQYNFAPLA
                     ILLISISEMVPLLSQLFLGILGDFQENRVKHALCIAKIKILLYAILTVFLVLSPFSLV
                     SVIMIVIINLISDTLSYLSAYMMNALYISVIKDDLHDAMGFRQSLMRVVRIVANLAGA
                     FLINVISIQTISLINTLTFVIAFLGLYVIRHTLYEVEKRIEMSHTALSFKKYFQHLKQ
                     SLAVLLKLKDTVILLFLTTSMIAILDVSPRLIALRFIQQTLAQLSIGQLLALLSIIMS
                     CGAILGNMTSSNLFKNIRFTHLLVFCEISLLALITSILCQAYIVIFMTSFISSTIIGI
                     LSPRLQAAVFAYIPSDKMGTVGSALSTVDILAPSLLSLLALSIASGVSVQLALIFLYL
                     ILIALIFCQWLVKFNTHN"
     gene            complement(19546..20016)
                     /locus_tag="VQ862_001358"
     CDS             complement(19546..20016)
                     /locus_tag="VQ862_001358"
                     /inference="COORDINATES: protein motif:HMM:NF017000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3115704.1"
                     /translation="MTILLKLSSTIVYGEIYHYFLQRDTAKESILDYSFAHGYCGIAY
                     ALFAYSKVLEPSMFYNDLHTFHTELKKLLEKVTSNTENLGNLQLSWCKGISGIILYLC
                     MYDCDGNKDIISKYQEFVFNHHLKMMTGYCHGITSLLQTTVYNQNKLLMKKSNR"
     gene            complement(20183..20593)
                     /locus_tag="VQ862_001359"
     CDS             complement(20183..20593)
                     /locus_tag="VQ862_001359"
                     /inference="COORDINATES: protein motif:HMM:NF017000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3115705.1"
                     /translation="MQLLELSHTQGQLTDEQLFWLQCLLNLSQTNNLVKIKKIEEHKY
                     DYKTECNSVLRFLLDKTVNSEGRITSSTEFGNFVSNLSFQHGIAGLLFPLNKLYHPEL
                     DSKILSIIKKAVTIRTSHTYEYQYSLLFGGAGYL"
BASE COUNT         6436 a         3742 c         4636 g         5872 t
ORIGIN      
        1 agttctctag tctggagatt tttcaataga cttcgttatt gggcggttac gatattcata
       61 ttttttgcaa agatgttgtt tgaaaaataa ttttcaaaaa ttctgaaaat tctgttgaca
      121 tctttctgaa aagagtctat aatggagaga aagttttaaa ggagaaaatg atgaaaagtt
      181 caaaactatt tgcccttgcg ggcgtgacat tattggcggc gactacttta gctgcatgct
      241 ctggatcagg ttcaagtact aaaggtgaga agacattctc atacatttat gagacagacc
      301 ctgataacct caactatttg acaactgcta aggctgcgac agcaaatatt accagtaacg
      361 tggttgatgg tttgctagaa aatgatcgct acgggaactt tgtgccgtct atggctgagg
      421 attggtctgt atccaaggat ggattgactt acacttatac tatccgtaag gatgcaaaat
      481 ggtatacttc tgaaggtgaa gaatacgcgg cagtcaaagc tcaagacttt gtaacaggac
      541 taaaatatgc tgctgataaa aaatcagatg ctctttacct tgttcaagaa tcaatcaaag
      601 ggttggatgc ctatgtaaaa ggggaaatca aagatttctc acaagtagga attaaggctc
      661 tggatgaaca gacagttcag tacactttga acaaaccaga aagcttctgg aattctaaga
      721 caaccatggg tgtgcttgcg ccagttaatg aagagttttt gaattcaaaa ggagatgatt
      781 ttgccaaagc tacggatcca agtagtctct tgtataacgg tccttatttg ttgaaatcca
      841 ttgtgaccaa atcctctgtt gaatttgcga aaaatccgaa ctactgggat aaggacaatg
      901 tgcatgttga caaagttaaa ttgtcattct gggatggtca agataccagc aaacctgcag
      961 aaaactttaa agatggtagc cttacagcag ctcgtctcta tccaacaagt gcaagtttcg
     1021 cagagcttga gaagagtatg aaggacaata ttgtctatac tcaacaagac tctattacgt
     1081 atctagttgg tacaaatatt gaccgtcagt cctataaata cacatctaag accagcgacg
     1141 aacaaaaggc atcgactaaa aaggctctct taaacaagga tttccgtcag gctattgcct
     1201 ttggatttga ccgtacagcc tatgcctctc agttgaatgg acaaactgga gcaagtaaaa
     1261 tcttgcgtaa tctctttgtg ccaccaacat ttgttcaagc agatggtaaa aactttggcg
     1321 atatggtcaa agagaaattg gtcacttatg gggatgaatg gaaggatgtt aatcttgcag
     1381 attctcagga tggtctttac aatccagaaa aagccaaggc tgaatttgct aaagctaaat
     1441 cagccttaca agcagaagga gtccaattcc caattcattt ggatatgcca gttgaccaga
     1501 cagcaactac aaaagttcag cgcgtccaat ctatgaaaca atccttggaa gcaactttag
     1561 gagctgataa tgtcattatt gatatccaac aactacaaaa agacgaagta aacaatatta
     1621 catattttgc tgaaaatgct gctggcgaag attgggattt atcagataat gtcggttggg
     1681 gtccagactt tgccgatcca tcaacctacc ttgatatcat caaaccatct gtaggagaaa
     1741 gtactaaaac atatttaggg tttgactcag gggaagataa tgtagctgct aaaaaagtag
     1801 gtctatatga ctacgaaaaa ttggttactg aggctggtga tgaggctaca gatgttgcta
     1861 aacgctatga taaatacgct gcagcccaag cttggttgac agatagtgct ttgattattc
     1921 caactacatc tcgtacaggg cgtccaatct tgtctaagat ggtaccattt acaataccat
     1981 ttgcattgtc aggaaataaa ggtacaagtg aaccagtctt gtataaatac ttggaacttc
     2041 aagacaaggc agtcactgta gatgaatacc aaaaagctca ggaaaaatgg atgaaagaaa
     2101 aagaagagtc taataaaaag gctcaagaag atctcgcaaa acatgtgaaa taactgttgc
     2161 aaaatataag aaaggattta gtatttctct tgaatgctga atcctttttt acatttgtaa
     2221 agaaagcttc taaatgtact gacccccaaa agttggagcc tctttttgtc agaatagaga
     2281 aaatttttgt taattttact tgtttcctat tgctttctca gttattattt gttatattaa
     2341 aagtataatt attttttatt tatcagggtt aagcattgca ctttcagagg aaggagtatt
     2401 ttttaaaaag gaaatgtaaa cgcttgctaa aaaatgaaag gatttagaag tttatgaata
     2461 aaggattatt tgaaaaacgt tgtaaatata gtattcggaa attttcatta ggtgttgctt
     2521 ctgttatgat tggagctgca ttctttggga caagtccggt tcttgcagat agcgtgcagt
     2581 ctggttccac ggcgaactta ccagctgatt tagctactgc tcttgcaaca gcaaaagaga
     2641 atgatggacg tgattttgaa gcgcctaagg tgggagaaga ccaaggttct ccagaagtta
     2701 cagatggacc taagacagaa gaagaactat tagcacttga aaaagaaaaa ccggctgaag
     2761 aaaaaccaaa agaggataaa cctgcagctg ctaaacctga aacacctaag acggtaaccc
     2821 ctgaatggaa aacggtagag aaaaaagaac aaaagggaac agtcactatc cgagaagaaa
     2881 aaggtgtccg ctacaaccaa ctatcctcaa ctgctcaaaa tgataacgca ggtaaaccag
     2941 ccctgtttga aaagaagggc ttgaccgttg atgccaatgg aaatgcaact gttgatttaa
     3001 ccttcaaaga tgattctgaa aagggcaaat cacgctttgg tgtcttcttg aaatttaaag
     3061 ataccaataa taatgttttt gtcggttatg acaaggatgg ctggttctgg gagtataaat
     3121 ctccaacaac tagcacttgg tatagaggta gtcgtgttgc tgctcctgaa acaggatcaa
     3181 caaaccgtct ctctatcact ctcaagtcag acggtcagct aaatgccagc aataacgatg
     3241 tcaatctctt tgacacagtg actctaccag ctgcggtcaa tgaccatctt aaaaatgaga
     3301 agaagatcct tctcaaggcg ggctcttatg acgatgagcg aacagttgtt agcgttaaaa
     3361 cggataacca agagggggta aaaacagagg atacccctgc tgaaaaagaa acaggtcctg
     3421 aagttgatga tagcaaggtg acttatgaca cgattcagtc taaggtcctc aaagcagtga
     3481 ttgaccaagc cttccctcgt gtcaaggaat acaccttgaa tggacatact ttgccaggac
     3541 aggtgcaaca gttcaaccaa gtctttatca ataaccaccg aatcacccct gaagtcactt
     3601 ataagaaaat caatgagaca acagcagagt acttgatgaa gcttcgcgat gatgctcact
     3661 taatcaatgc ggaaatgaca gtacgcttgc aagttgtgga caatcaattg cactttgatg
     3721 tgaccaagat tgtcaaccac aatcaagtca ctccaggtca aaagattgat gacgaaagaa
     3781 aactactttc ttctattagt ttcctcggca atgctttagt ctctgtttct agtgatcaaa
     3841 ctggtgctaa gtttgatggg gcaaccatgt caaacaatac gcatgtcagc ggagatgatc
     3901 atatcgatgt aaccaatcca atgaaggatt tggctaaggg ttacatgtat ggatttgttt
     3961 ctacagataa gcttgctgct ggtgtttgga gtaactctca aaacagctat ggtggtggtt
     4021 cgaatgactg gactcgtttg acagcttata aagaaacagt cggaaatgcc aactatgtag
     4081 gaatccacag ctctgaatgg caatgggaaa aagcttataa gggcattgtt ttcccagaat
     4141 acacgaagga acttccaagt gctaaggttg ttatcactga agatgccaat gcagacaaga
     4201 acgttgattg gcaagatggt gccattgctt atcgtagcat tatgaacaat cctcaaggtt
     4261 gggaaaaagt taaggatatc acagcttacc gtatcgcgat gaactttggt tctcaagcac
     4321 aaaacccatt ccttatgacc ttggatggta tcaagaaaat caatctccat acagatggtc
     4381 ttgggcaagg tgttctcctt aaaggatatg gtagcgaagg ccatgactct ggtcacttga
     4441 actatgctga tattggtaag cgtatcggtg gtgtcgaaga cttcaagacc ctaattgaga
     4501 aggctaagaa atatggagct catctaggta tccacgttaa cgcttcagaa acttatcctg
     4561 agtctaaata cttcaatgaa aaaattctcc gtaagaatcc agatggaagc tatagctatg
     4621 gttggaactg gctagatcaa ggtatcaaca ttgatgctgc ctatgaccta gctcatggtc
     4681 gtttggcacg ttgggaagat ttgaagaaaa aacttggtga cggtctcgac tttatctatg
     4741 tggacgtttg gggtaatggt caatcaggtg ataacggtgc ctgggctacc cacgttcttg
     4801 ctaaagaaat taacaaacaa ggctggcgct ttgcgatcga gtggggccat ggtggtgagt
     4861 acgactctac cttccatcac tgggcagctg acttgaccta cggtggctac accaataaag
     4921 gtatcaacag tgccatcacc cgctttatcc gtaaccacca aaaagatgct tgggtagggg
     4981 actacagaag ttatggtggt gcagccaact atccactgct aggtggctac agcatgaaag
     5041 actttgaagg ctggcaagga agaagtgact acaatggcta tgtgactaac ctctttgctc
     5101 atgacgtcat gactaagtac ttccaacact tcactgtaag taaatgggaa aatggtacac
     5161 cggtgactat gaccgataac ggtagcacct ataaatggac tccagaaatg cgagtggagt
     5221 tggtagatgc tgacaataat aaagtagttg taactcgtaa gtcaaatgat gtcaatagcc
     5281 cacaatatcg cgaacgtaca gtaacgctca acggacgtgt catccaagat ggttcagctt
     5341 acttgactcc ttggaactgg gatgcaaatg gtaagaaact ttctactgag aaggaaaaga
     5401 tgtactactt caatacgcag gccggtacaa caacttggac ccttccaagc gattgggcaa
     5461 agagcaaggt ttacctttac aagctaactg accaaggtaa gacagaagag caagaactaa
     5521 ctgtaaaaga tggtaaaatt accctagatc ttctagcaaa tcaaccatac gttctctatc
     5581 gttcgaaaca aaccaatcct gaaatgtcat ggagtgaagg catgcacatc tatgaccaag
     5641 gatttaatag cggtaccttg aaacattgga ccatttcagg cgatgcttct aaggcagaaa
     5701 ttgtcaagtc tcaaggggca aacgatatgc ttcgtattca aggaaacaaa gaaaaagtta
     5761 gtctcactca gaaattaact ggcttgaaac caaataccaa gtatgccgtt tatgtcggtg
     5821 tcgataaccg tagtaatgcc aaggcgatca tcactgtaaa cactggtgaa aaagaagtga
     5881 ctacttatac caataagtct ctcgctctca actatgttaa ggcctacgcc cacaatacac
     5941 gtcgtgacaa tgctacagtt gacgatacaa gttacttcca aaacatgtac gccttcttta
     6001 caactggatc ggacgtctca aatgttactc tgacattgag tcgtgaagct ggtgatgaag
     6061 caacttactt tgatgaaatt cgtacctttg aaaacaattc aagcatgtac ggagacaagc
     6121 atgatacagg tcaaggaacc ttcaagcaag actttgaaaa tgttgctcag ggtatcttcc
     6181 catttgtagt gggtggtgtc gaaggtgtcg aagacaaccg cactcacttg tctgaaaaac
     6241 acgatccata tacacaacgt ggttggaacg gtaagaaagt tgatgatgtt atcgaaggaa
     6301 attggtcact caagacaaat ggactagtga gccgtcgtaa cttggtttac caaactattc
     6361 cgcaaaactt ccgttttgaa gcaggtaaga cctaccgtgt aacctttgaa tacgaagcag
     6421 gttcagacaa tacctatgct tttgtagtcg gtaagggaga attccagtca ggtcgtcgtg
     6481 gtactcaagc aagcaacttg gaaatgcatg aattgccaaa tacttggaca gattctaaga
     6541 aagccaagaa ggcaaccttc ctcgtgacag gtgcagaaac aggggatact tgggtaggta
     6601 tctactcaac tggaaatgca agtaatactc gtggtgattc tggtggaaat gccaacttcc
     6661 gtggttataa cgacttcatg atggataatc ttcaaatcga agaaattacc ctaacaggta
     6721 atatgttgac agaaaatgct ctgaagaact acttgccaac ggttgccatg actaactaca
     6781 ccaaagagtc tatggatgct ttgaaagagg cggtctttaa ccttagtcag gccgatgatg
     6841 atatcagtgt ggaagaagcg cgtgcagaga ttgccaagat tgaaaccttg aagaatgctt
     6901 tggttcagaa gaaaacggct ttggtagcag atgactttgc aagtcttaca gctcctgctc
     6961 aggctcaaga aggtcttgca aatgcctttg atggaaactt atctagtcta tggcatacat
     7021 cttggaatgg tggagatgta ggcaagcctg caaccatggt cttgaaagaa ccaactgaaa
     7081 tcactggact tcgttatgtt ccacgtggat caggttcaaa tggtaacttg cgtgatgtga
     7141 aacttgttgt gacagatgag tctggcaagg agcatacctt tactgcaact gattggccag
     7201 ataacaataa gccaaaagac attgattttg gtaagacaat taaggctaag aaaattgtcc
     7261 ttacaggtac taagacttac ggagatggtg gcgataaata ccaatctgca gcggaactca
     7321 tctttactcg tccacaggta gcagaaacac ctcttgactt gtcaggctat gaagcagctt
     7381 tgactaaggc tcagaaatta acagacaaag acaatcaaga ggaagtagct agcgttcagg
     7441 caagcatgaa atatgcgacg gataaccatc tcttgacgga aagaatggtg gaatactttg
     7501 cagattatct caaccaatta aaagattctg ctacgaaacc agatgctcca actgtagaga
     7561 aacctgagtt taaacttagc tctttagctt ccgagcaagg taagacgcca gattataagc
     7621 aagaaatagc tagaccagaa acacctgaac aaatcttgcc agcaacaggt gagagtcaat
     7681 ctgacacagc cctcttccta gcaggtgtta gcctagccct atctgctctc tttgtagtaa
     7741 aaacgaagaa agactagtat ttagtaaaac ctcttaacaa gattacggaa gcagtctcta
     7801 tcttttccaa tgaggtttat agtacagaaa aagcctgaga agatgtcttc tcaggctttt
     7861 gttaagcaca taaatacaat agtgctatga aaaaatcacc cagaaaaatc tgggtgataa
     7921 atgttatggt tgtgctgatt gaggattctg attttgttga tcaggggttg tatttgattg
     7981 ttgcgtatta ttgttaggat tggtagtcgt actattattt gtgcttggag tggttgagct
     8041 agactgtgaa gttgaactat ctgatgatga gcttgaactt tcagttgatg ggggttgttg
     8101 tggagcaggt gagctccacg tagaacgagc accattttta aatacgaatt ctccatttct
     8161 gtagagcccc tctggtatat tccaatcctc tggattgctt ccttcagaca ggtaggtcat
     8221 catagagcgg taaactttgg cagcgaccgt aaggccattg cctacaagtg gtgtcagacg
     8281 gttagaatag cctgtccata cagccattga atatttacgc gtatagccag caaatagttc
     8341 atcaggtgct acaaattgag aggtcttgat gtggttttca atttcctcgt ctgtatagtt
     8401 agaggttcct gttttaccag cctgagggag ccaagcaaga taggcatttc gtccagttcc
     8461 ataactcaag actgttttca tcatgtcggt catcatatag gctgtcgttt ccttcatggc
     8521 acgagttccg acattagaga actctttttc actcccatca ctaaagacga ctttatggat
     8581 atacattggt ttatagtaag ttccaccatt tgcaaaggca gcgtaagcag cagccatctt
     8641 ttcactactt gctccatatt ttttgtctga ttcggttgtg ttacttgaaa tggcatttga
     8701 gtagtgaata cttgggtagt cgattccgag accatttagg aaagtcttgg cgcggttgag
     8761 tccgaccttg tttagagttt ccacggctgg gacgtttcgc gattgttgca gggcgtattg
     8821 caaggtgatg ttgccaaagt agcccctatc ccagttataa acaggagtat ttgtcccagg
     8881 gtagttatag ggctcatcgt gaacgatagt agcagttgaa tcgtagacac cgtactccaa
     8941 ggcaggagca tagtctgtga tcggtttcat agttgatccc cagtcgcggt ttgtttctac
     9001 tgcttggtta attccgaagg aaacattact tgactgatgg cgtgctccta gctgggcaat
     9061 gactttaccg ttagaaacat caacaatggt agaagcgact tgcaattcat cgtctggata
     9121 ggcaacgtat tcgtctgtat tgtaaatatc ccacagatgt ttttgagctt cttggtctac
     9181 atttgtgtag acatccatcc cagttgtgag caggttatag cctgtttctt cttcaacttg
     9241 attgatgact tccttgaggt aattatccat gtaagcaggg taattacttg ctgatttgag
     9301 actttgtagt ccatcagtaa ttggtgtatt gactgctttc tcatactgtt cagcagagat
     9361 gtagccttga tttttcattt cagataagac caagtttcgg cggtcttggg ctgcttctgg
     9421 atgtgaatag gggtcatatt ggtttggtgc ctgaggcatt ccagccagca aggctaactg
     9481 aggtaaactt aaattattga ggtctttacc atagtagttt tgagctgctg tctgcattcc
     9541 atagttccca ttagacatgt agaccttatt tatatagtag gtcaagattt cttgcttggt
     9601 tgctttttgt tctaactgaa tcgctaacca agcttcctga gccttacgag aaatagtctg
     9661 gtcggaagtc gaagttgaaa agtaagtcaa cttaatcaac tgttgagtga gagttgatcc
     9721 accttggagg gaattgcttt gcagattgcg caagaaagct cccaggatac ggatggtatc
     9781 aatccccctg tggtcgaaga agcgatggtc ttcgatagaa acgattgcct taaccaaatc
     9841 tgtgggaata tcattagctt gggcattgac gcggcgttca gaacccaagt cagcaatgag
     9901 ttgattttta ttgtcgtaga ttttactaga agttgttgca actagtttac tctcggatag
     9961 gctaggagcc ttgctaacgt agtagaaaaa aactcctccg cctaagacaa tggctgcgat
    10021 aaccaagctt aagaagctaa tgctcagata cttgattagg cgcagaatcg ttggtttgtt
    10081 catcttgttt taccacctaa taaatgttct ttgataacat tgagataagg aatttgaggg
    10141 aaggcaccag ccttgatttc atatccatat tctcgaatat attcaagtgg cattgatttt
    10201 tgtctcttat cttgatgata gaagcgaatc aaatcgaatg ccggcaataa gtaggtttct
    10261 tgctgagaag aaaagtgaag aaggacaaag cagattcctt gttgggcaag gacttgttcc
    10321 atatgctgaa tctgatgtgg atgaaaattt ttcatcggaa tcgcacgttt ttgttttgtt
    10381 tccttgactt caaagtcgat gtaatatcca ttataaacgc cagaatagtc cgtcgttgaa
    10441 gcttgtcgaa aataggcttc aacaatcttg gcacgacttc gttgtggata gtccacttgt
    10501 acgatttgaa taggagttgg tttcttatgt ataacagcca agccctgaga caaatagtag
    10561 tcgttggtag cattgatcat cttttcaaaa gacattcctc gatttgcgaa atttttgggt
    10621 tgagaaagag atgtttgtct tttttgtgat gaaactttat gtggatagtt gaccataatt
    10681 ctccttattg gtacaataac atcactttat tataccataa tttgcacaga aagggttaaa
    10741 aatggctaca gctttggttt taggctattc tgcttttgat ttgggtttat tttctgataa
    10801 ggatcctcgt cttaaattga ttaaaaaagc gatacgtaaa gatttagagg ctatggcagc
    10861 agatggggtg tcttggcttg tgtttacagg gagtttgggt tttgaatatt gggttttaga
    10921 ggttgctcag gagatgaaaa ccgaatacgg tttccagttg gccaccattt ttgcttttga
    10981 aacccatggg gaaaattgga atgaaggcaa tcagatgaaa ctgagtcgct ttaagcaggt
    11041 agactttgtc aaatatgctt atcctcgcta tgaacacaag gggcagttaa gagattacca
    11101 gcagtttttg ctggaaaaca cgactagttc ctatcttttt tatgatgaag aaaatgaaac
    11161 aaaactagct tatttttacc aaaagatgaa aaatcaagag gactatttta taaagagatt
    11221 aacatttgat gaattaaatg aacttgctga aaatttttcc gaaaattgaa gctttgacct
    11281 tgatttttgt ttgccttttt ttatataata atactagcaa gcgagaatgg agagagacat
    11341 ggcaagtatt attttttcag cgaaagatat ttttgaacaa gagtttggac gtgaagtccg
    11401 tggctataat aaagtagaag ttgacgagtt tttagacgat gtcatcaagg actatgaaac
    11461 ctatgctgcc ttggtcaagt cacttcgtca ggaaattgcg gatttgaagg aagaattaac
    11521 tcgtaaaccg aaaccttcac cagttcaagc agaacccctt gaagcggcaa ttacaagttc
    11581 tatgacgaat tttgatattt tgaaacgcct gaatagattg gaaaaagaag tttttggtaa
    11641 acaaatttta gataactcag atttttaagt agttatttga gatgtgcaat ttttggataa
    11701 tcgcgtgagg agaattgctt ctcatgagga aagtccatgc tagcacaggc tgtgatgcct
    11761 gtagtgtttg tgctaggcga aaccataagc ctagggacga gaaatcgtta cggcagttga
    11821 aatggctaag tccttggata ggccagagta ggcttgaaag tgccacagtg acggagtctt
    11881 tctggaaaca gagagagtgg aacgcggtaa acccctcaag ctagcaaccc aaattttggt
    11941 cggggcatgg agtacgcgga aacgaacgta gtattctgac tgctatcagc tagagctgtt
    12001 agtggtagac agatgattat cgaaggaagt ggtcctagtc acttctggaa caaaacatgg
    12061 cttatagaaa attgcatata ggttggggct gagaaatttt ctcaacctca ttttttaaag
    12121 tggacatata gaaaggtctt gcaagactgt aacatgaaaa aagaatttaa tttaattgca
    12181 actgtggcag cagggcttga ggctgtcgtt ggtcgtgaag tgcgagagtt gggctacgat
    12241 tgtcaggttg aaaatggacg tgttcgtttt caaggagacg tgagagctat tatcgaaacc
    12301 aacctttggc ttcgggcagc agatcgtatc aaaattatcg taggaacgtt cccagctaag
    12361 acttttgaag agctatttca gggagttttc gctttagatt gggaaaatta tttaccactt
    12421 ggagctcggt tcccgatttc aaaagctaaa tgtgttaagt ccaaacttca caatgagccc
    12481 agtgttcagg ctatttctaa gaaagctgtt gtcaagaaat tgcagaaaca ctatgctcgc
    12541 ccagaagggg ttcctctgat ggagaatggc ccagagttta agattgaggt ctctattctc
    12601 aaagatgtgg caactgtcat gattgatacg accgggtcta gcctctttaa acgtggttat
    12661 cgtaccgaaa aaggtggcgc tcctatcaag gaaaatatgg cagcagccat tttacaactt
    12721 tctaactggt atccagacaa gcctttgatt gatccgacct gtggttcggg gactttctgt
    12781 attgaggcag ttatgattgc tagaaagatg gcgccaggtc ttcgtcgctc ttttgcattt
    12841 gaggaatgga actggatcag cgatcgcttg attcaagaag tgcgcacaga agcggctaaa
    12901 aaagtagaac gtgagcttga gttggatatc atgggctgtg atattgatgc tcgcatggtg
    12961 gaaattgcta aggccaatgc tcaggcagct ggtgttgcag gagacattac ttttaagcag
    13021 atgcgcgtgc aggatttacg ttccgataaa atcaatggag taatcatttc caatccgcct
    13081 tatggtgaac gtttgtcaga tgatgcaggg gtgaccaagc tctatgctga gatggggcaa
    13141 gtatttgcac cgctgaaaac ttggagcaaa tttatcctga ctagtgatga agcttttgaa
    13201 agcaagtatg gtagccaagc agataagaag cgtaagttat acaacggaac cttgaaagtg
    13261 gatctatatc aatattttgg tcagcgtgtc aaacggcaag aggtaaaata gaaagggata
    13321 ctcatgagta aaaaaagacg aaatcgtcat aaaaaagaag gtcaagaacc gcaatttgat
    13381 tttgatgaag caaaagagct aacagttggt caagctattc gtaaaaatga agaagtggaa
    13441 gcaggagtct tgcctgagga ttccattttg gacaagtatg ttaagcaaca cagagatgaa
    13501 attgaggcgg ataagtttgc gactcgtcaa tacaaaaaag aggagttcgt tgaaactcag
    13561 agtctggatg atttaattca agagatgcgt gaggctgtag agaagtcaga agcttcttcg
    13621 gaggaagttc catcttctga agacatctta ctacccttgc ctctggacga tgaggagcaa
    13681 ggcttggatc ctctattgct agatgatgaa aatccaacag aaatgactga agaagtggaa
    13741 gaggagcaaa acctttctcg tctggatcaa gaggactcag aaaagaaaag taaaaaaggc
    13801 tttattttga ccgttttggc gcttgtatca gtaattattt gtgtcagtgc ttattatgtc
    13861 taccgtcaag tggctcgttc gaccaaggaa attgaaactt ctcaatcaac tacagccaat
    13921 caatcagatg tggatgattt taatacactt tatgacgcct tttacacaga tagcaataaa
    13981 acggctttga aaaatagcca gtttgataaa ctgagtcaac tcaaaacctt gcttgataaa
    14041 ctggaaggta gtcgtgaaca tacgcttgcc aaatctaaat atgatagtct agcaacgcaa
    14101 atcaaggcta ttcaagatgt caatgcacaa tttgaaaaac cagctattgt ggatggtgtg
    14161 ttggatacca atgccaaagc caaatcggat gctaaattta cggatattaa aactggaaat
    14221 acggagcttg ataaagtgct agataaggct atcagtcttg gtaagagcca gcaaacaagt
    14281 acttctagct caagttcaag tcaaactagc agctcaagct ctagtcaagc aagttcaaat
    14341 acgactagtg agccaaaacc aagtagttca aatgagacta gaagtagtcg cagtgaagtc
    14401 aatatgggtc tctcgagtgc aggggttgct gttcaaagaa gtgccagtcg tgttgcctat
    14461 aatcagtctg ctattgatga tagtaataac tctgcctggg attttgcgga tggtgtcttg
    14521 gaacaaattc tagcgacttc acgttcacgt ggctatatca ctggagacca atatatcctt
    14581 gaacgtgtca atatcgttaa cggcaatggt tattacaacc tctataagcc agatggaacc
    14641 tatctcttta cccttaactg taagacaggc tactttgtcg gaaatggcgc tggtcatgcg
    14701 gatgacttgg actactaagc agtcgttaca aaattctttc ttttcaaaag taaaaatgat
    14761 aaaataaaac aaatgaaaca agaggagtgt caaatgacaa aagctaactt tggtgtcgta
    14821 ggtatggccg taatgggtcg taaccttgcc cttaatattg aatcacgtgg ttacacagtt
    14881 gctatctaca accgtagtaa agaaaaaacg gaagatgtga ttgcttgcca tcctgaaaag
    14941 aactttgtac caagctatga cgttgaaagt tttgtaaact caatcgaaaa acctcgtcgt
    15001 atcatgctga tggttcaagc tggacctggt acagatgcta ctatccaagc ccttcttcca
    15061 caccttgaca agggtgatat cttgattgac ggtggaaata ctttctacaa agataccatc
    15121 cgtcgtaatg aagaattggc aaactcaggt atcaacttta tcggtactgg agtttctggt
    15181 ggtgaaaaag gtgcccttga aggtccttct atcatgcctg gtggacaaaa agaggcctac
    15241 gaattggttg cggatgttct tgaagaaatc tcagctaaag caccagaaga tggcaagcca
    15301 tgtgtgactt acatcggtcc tgatggagct ggtcactatg tgaaaatggt tcacaatggt
    15361 attgagtacg gtgatatgca attgatcgca gaaagctatg acttgatgca acacttgcta
    15421 ggcctttctg cagaggatat ggctgaaatc tttactgagt ggaacaaggg tgaattagac
    15481 agctacttga tcgaaatcac agctgatatc ttgagccgta aagacgatga aggccaagat
    15541 ggaccaatcg tagactacat ccttgatgct gcaggtaaca agggaactgg taaatggacg
    15601 agccaatcat ctcttgacct tggtgtacca ttgtcactga ttactgagtc agtgtttgca
    15661 cgctacattt caacttacaa ggaagaacgt gtacatgcta gcaaggtgct tccaaaacca
    15721 gctgccttca actttgaagg agacaaggct gaattgattg aaaaaatccg tcaagccctt
    15781 tacttctcaa aaatcatttc atacgcacaa ggatttgctc aattgcgtgt agcctctaaa
    15841 gaaaacaact ggaacttgcc atttgcagat atcgcatcta tctggcgtga tggctgtatc
    15901 atccgttctc gtttcttgca aaagattaca gatgcttaca accgcgatgc agatcttgcc
    15961 aaccttcttt tggacgagta cttcttggat gttactgcta agtatcaaca agcagtgcgt
    16021 gatatcgtag ctcttgcggt tcaagctggt gtgccagtgc caactttctc agcagctatt
    16081 acttactttg atagctaccg ttcagctgac cttccagcta acttgatcca agcacaacgt
    16141 gactactttg gtgctcacac ttaccaacgt aaagacaaag aaggaacctt ccactactct
    16201 tggtatgacg aaaaataagt aggtcagcca tggggaaacg gattttatta cttgagaaag
    16261 aacgaaatct agctcatttt ttaagtttgg aactccagaa agagcagtat cgggttgatc
    16321 tggtagagga ggggcaaaaa gccctctcca tggctcttca gacagactat gatttgatgt
    16381 tattgaacgt taatctggga gatatgatgg ctcaggattt tgcagaaaaa ttgagtcgaa
    16441 ctaaacctgc ctcagtcatc atgattttag atcattggga agacttgcaa gaagagctgg
    16501 aagttgttca gcgttttgca gtttcataca tttataagcc agtccttatc gaaaatctgg
    16561 tagcgcgtat ttcggcgatc ttccgaggtc gggacttcat tgatcaacac tgcagtctga
    16621 tgaaagttcc aaggacctac cgcaatctta ggatagatgt tgaacatcac acggtttatc
    16681 gtggtgaaga gatgattgct ctgacccgcc gtgagtatga ccttttggcg acacttatgg
    16741 gaagcaagaa agtattgact cgtgagcaat tgttggaaag tgtttggaag tatgaaagtg
    16801 cgaccgagac aaatatcgta gatgtctata tccgctatct acggagcaag cttgatgtta
    16861 aaggccaaaa aagctacatt aaaaccgtgc gtggtgttgg atataccatg caagaataga
    16921 taagcagttg cagttgtgta actgcttttt tgaggagttt ttatatattg acatgcagtc
    16981 gggtctttgc tacaatcgtt ttaggaggat atatagatga aacttttgaa aaaaatgatg
    17041 caagttctac tagcagtctt tttctttggt ttgctagcta caaatacggt atttgcgaat
    17101 accacaggtg gccgatttgt tgataaggat aatagaaaat attatgtaaa agatgatcat
    17161 aaagcaatct attggcataa aatagacggt aaaacttact attttggtga tattggagag
    17221 atggttgtcg gttggcaata cttagaaatt cctggaacag gttatcgtga taatttattc
    17281 gataaccaac cagttaatga aattggcctt caggagaagt ggtactattt tggacaagat
    17341 ggtgctttgc tagaacaaac agataaacaa gtactagagg caaaaacgtc tgaaaataca
    17401 ggaaaagtat acggtgaaca atatcctcta tctgctgaaa agagaactta ttattttgat
    17461 aataattatg ctgtaaagac aggctggatt tatgaagacg gcaattggta ttatttaaat
    17521 aagctaggaa attttggcga tgattcttac aatccactac caattagtga agttgctaag
    17581 ggttggactc aagattttca tgttactatt gacattgata gaagcaaacc tgctccatgg
    17641 tactacctag acccagaaac tggcattatg cgaacaggat ggcaatatct aggtaataac
    17701 tggtactacc tccgttcatc aggagcaatg gccactggct ggtatcagga aggtaccact
    17761 tggtattatt tagaccagcc aaatggcgat atgaaaacag gttggcaaaa ccttgggaac
    17821 aaatggtact atctccgttc atcaggagct atggcaactg gttggtatca agatggttca
    17881 acttggtact acctaaatgc aggtaatgga gacatgaaga caggttggtt ccaggtcaat
    17941 ggcaactggt actatgctta tagctcaggt gctttggcag tgaatacgac cgtagatggc
    18001 tattctgtca actataatgg cgaatgggtt cggtaatgac agggcgctta taattatatt
    18061 agaacactcg cttaatcaaa gaagtgactt tgttgtactt gacctgacga ttggggagat
    18121 taaaagcatg tgaaatctac acatgctttt tcgttagtta tgagtgttga acttgactaa
    18181 ccattgacaa aagataagag caattaaaat aagatacaaa aatatcaatg ctaactgcac
    18241 cgaaacgccc gatgctatgg atagggctaa tagggagagc agggacgggg cgagaatgtc
    18301 cactgtgctc agagcagagc ccaccgtccc catcttgtca ctggggatat aggcaaagac
    18361 agctgcttgt aggcgagggc tgagaatgcc gataatcgta gaactgatga aactggtcat
    18421 gaaaattacg atataggctt gacaaaggat actagttatt agagccaata gggaaatctc
    18481 acagaaaacc aagaggtgcg tgaaacggat atttttaaat agattactgc tggtcatatt
    18541 gccaaggata gctccacaag acatgatgat ggagagcagg gcgaggagtt gcccaatgct
    18601 cagttgtgct agtgtctgtt ggatgaagcg gagggcaatc agccgagggg acacatccaa
    18661 gatggcaatc atactggtcg tcagaaacag tagtatgacg gtatctttta acttcagtag
    18721 cacagccagc gactgtttaa gatgttgaaa atatttctta aaactcagtg ctgtatgtga
    18781 catttcaatc cttttttcaa cctcatacaa ggtatgtcga ataacataca ggcccaaaaa
    18841 ggcaatgaca aaagtcagag tgttgataag ggaaatagtt tgaatactta taacattgat
    18901 aaggaatgcg ccagccagat tggcgacaat gcggacaacc ctcatcagag actgcctgaa
    18961 ccccatggca tcatgcaggt cgtccttaat tacactgatg tagagggcgt tcatcatgta
    19021 ggcagacagg tagctcaagg tgtcagagat gaggttgatg atgacaatca taatgactga
    19081 aactaatgaa aagggcgaca agacgagaaa tactgtcaaa atagcgtaga gcaggatttt
    19141 gattttggca atacagagtg cgtgtttgac tctattttct tgaaaatctc ctagaatccc
    19201 gagaaagagt tgcgatagta ggggaaccat ctctgaaatg gaaatcagta aaatcgctag
    19261 cggagcgaaa ttgtactgag ccacataatt gataatggcg aggtagaaaa tactgtcgcc
    19321 gaatgatgaa aaacagctgt ttagcagcaa ctgtctatat atgttgtttg tccaaaataa
    19381 tttcatacat ttctccttat gtctgcacat cgaatgggaa tttattattt aatagacacc
    19441 aatatacccc catgcttcct attccgaagt caaacaaatc tgctttacca ctatctcctt
    19501 gaaacatcag taaaccgtga tcatctcgtt cagaacatgc taaaattacc tgttggattt
    19561 tttcatcagt aatttgtttt gattgtagac agtggtttgt agtaagctag ttattccgtg
    19621 gcaatatcct gtcatcattt ttagatgatg gttaaaaaca aattcttgat atttactaat
    19681 aatatctttg tttccgtcac aatcgtacat acaaagatat aagattattc cggaaattcc
    19741 tttgcaccaa gaaagttgta aatttcctaa attttcagta ttagaagtaa ctttttctaa
    19801 taattttttt aattcagtat ggaatgtatg gagatcatta tagaacatag aaggttctaa
    19861 gactttagaa taggcaaata aagcatatgc aattccacaa tatccatgag caaagctata
    19921 gtctaaaatg ctttctttgg ctgtatctct ttgtaggaaa taatgataaa tttccccata
    19981 tactattgtg gatgaaagtt ttaagagtat tgtcattggt aacttgatag tattttatta
    20041 atgataatag gacaccagat tttcccaatg caaagtctat ttcctctaga gtatcataat
    20101 tctctattaa tttcttagcg gtgacgtttg ctaattgtag atagtattga tttttactga
    20161 tagaaaataa atgtaggagt aactatagat agcctgcacc accaaatagc agtgagtatt
    20221 gatattcata tgtgtgtgac gttctaattg tcactgcctt cttgatgata gagagtattt
    20281 tagaatccag ttctgggtgg tacaatttat ttagaggaaa cagtagtcca gctattccgt
    20341 gttggaatga taaattactt acgaaatttc caaattctgt tgaagaagtg atccttcctt
    20401 cagaatttac agttttatct agtaaaaatc gtagaacact attacattct gttttgtaat
    20461 catatttatg ttcctctatt tttttaattt tgactaaatt atttgtttga cttaaattta
    20521 gtagacattg taaccaaaat agttgctcat ctgtgagctg accttgagta tgtgatagtt
    20581 ctagtaattg aataggatcc tttagttaga ttcaatcaat ctataacaca acaacataat
    20641 aatactttta ggataacttg tcaaatatta tagtaaaatg aaataa
//
LOCUS       DAVBOD010000035        20010 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 640-05
            SAMEA1012484-rid20186543.denovo.035, whole genome shotgun sequence.
ACCESSION   DAVBOD010000035 DAVBOD010000000
VERSION     DAVBOD010000035.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012484
            Sequence Read Archive: ERR059358
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 20010)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20010)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979948.1
            Genome Coverage       :: 595x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:03:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,266
            CDSs (total)                      :: 2,219
            Genes (coding)                    :: 2,091
            CDSs (with protein)               :: 2,091
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 71 of 128
            Pseudo Genes (incomplete)         :: 50 of 128
            Pseudo Genes (internal stop)      :: 33 of 128
            Pseudo Genes (multiple problems)  :: 22 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20010
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012484-rid20186543.denovo.035"
                     /strain="NIG 640-05"
                     /db_xref="taxon:1313"
     gene            complement(65..1477)
                     /gene="sufB"
                     /locus_tag="VQ862_001360"
     CDS             complement(65..1477)
                     /gene="sufB"
                     /locus_tag="VQ862_001360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufB"
                     /protein_id="HET3115706.1"
                     /translation="MAEERVEPKPIDLGEYKFGFHDDVEPVLSTGKGLNEGVIRELSA
                     AKGEPEWMLEFRLKSYETFKKMPMQTWGADLSEIDFDDLIYYQKPSDKPARSWDDVPE
                     KIKETFERIGIPEAERAYLAGASAQYESEVVYHNMKEEFQKLGIIFTDTDSALKEYPD
                     LFNQYFAKLVPPTDNKLAALNSAVWSGGTFIYVPKGVKVDIPLQTYFRINNENIGQFE
                     RTLIIVDEGASVHYVEGCTAPTYSSNSLHAAIVEIFALDGAYMRYTTIQNWSDNVYNL
                     VTKRAKAQKDATVEWIDGNLGAKTTMKYPSVYLDGEGARGTMLSIAFANAGQHQDTGA
                     KMIHNAPHTSSSIVSKSIAKGGGKVDYRGQVTFNKNSKKSVSHIECDTIIMDDLSASD
                     TIPFNEIHNSQVALEHEAKVSKISEEQLYYLMSRGLSESEATEMIVMGFVEPFTKELP
                     MEYAVELNRLISYEMEGSVG"
     gene            complement(1531..1971)
                     /locus_tag="VQ862_001361"
     CDS             complement(1531..1971)
                     /locus_tag="VQ862_001361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SUF system NifU family Fe-S cluster assembly
                     protein"
                     /protein_id="HET3115707.1"
                     /translation="MALSKLDSLYMAVVADHSKNPHHQGKLEDAEQISLNNPTCGDVI
                     NLSVKFDAEDRLEDIAFLNSGCTISTASASMMTDAVLGKTKQEILELATIFSEMVQGQ
                     KDERQDQLGDAAFLSGVAKFPQRIKCATLAWNALKKTIENQEKQ"
     gene            complement(1958..3184)
                     /locus_tag="VQ862_001362"
     CDS             complement(1958..3184)
                     /locus_tag="VQ862_001362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000887707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HET3115708.1"
                     /translation="MLDVEAIRKDFPILDQIVNDEPLVYLDNAATTQKPLVVLKAINS
                     YYEQDNANVHRGVHTLAERATASYEAARETIRKFINAGSTKEVLFTRGTTTSLNWVAR
                     FAEEILTEGDQVLISVMEHHSNIIPWQEACRKTGAELVYVYLKDGALDMEDLRAKLTD
                     KVKFVSLAHASNVLGVVNPIKEITQLAHQVGAIMVVDGAQSTPHMKIDVQDLDLDFFA
                     FSGHKMAGPTGIGVLYGKEKYLEQMSPVEFGGEMIDFVYEQSASWKELPWKFEAGTPN
                     MAGAIGLATAVDYLEKIGMDAVEAHEQELIAYVYPKLQAIEGLTIYGSQDLAQRSGVI
                     AFNLGDLHPHDLATALDYEGVAVRAGHHCAQPLLQYLEVSATARASFYIYNTKADCDK
                     LVDALQKTKEFFNGTF"
     gene            complement(3195..4457)
                     /gene="sufD"
                     /locus_tag="VQ862_001363"
     CDS             complement(3195..4457)
                     /gene="sufD"
                     /locus_tag="VQ862_001363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufD"
                     /protein_id="HET3115709.1"
                     /translation="MTRENIKLFSEMHAEPSWLADLRQKAFDKIETLELPVIERVKFH
                     RWNLGDGTITENEPSANVPDFTALDHHLKLVQVGTQTVFEQTPVELAEQGVVFTDFHS
                     ALEEIPELIEEFFMSSVKYDDDKLAAYHTAYFNSGAVLYIPDNVEITEPIEGIFYQDS
                     DSNVPFNKHIMIIAGKNSKISYLERLESRGEGSDKATANITVEVIAHSGAQVKFAAID
                     RLGENVTAYISRRGKLGNDASIDWAIGVMNEGNVVADFDSDLIGNGSYADLKVVALSS
                     GRQVQGIDTRVTNYGCNSIGNILQHGVILEKATLTFNGIGHIIKGAKGADAQQESRVL
                     MLSDQARSDANPILLIDENDVTAGHAASIGQVDPEDMYYLMSRGLDKATAERLVVRGF
                     LGSVIVEIPVKEVRDEMIATIEEKLSKR"
     gene            complement(4485..5255)
                     /gene="sufC"
                     /locus_tag="VQ862_001364"
     CDS             complement(4485..5255)
                     /gene="sufC"
                     /locus_tag="VQ862_001364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000114488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly ATPase SufC"
                     /protein_id="HET3115710.1"
                     /translation="MSVIEIKDLHVEIEGKEILKGVNLTLKTGEIAAIMGPNGTGKST
                     LSAAIMGNPNYEVTKGEVLFDGVNILELEVDERARMGLFLAMQYPSEIPGITNAEFLR
                     AAMNAGKEDDEKISVREFITKLDEKMELLNMKEEMAERYLNEGFSGGEKKRNEILQLL
                     MLEPTFALLDEIDSGLDIDALKVVSKGVNAMRGEGFGAMIITHYQRLLNYITPDVVHV
                     MMEGRVVLSGGPELAARLEREGYAKLAEELGYDYKEEL"
     gene            complement(5405..5599)
                     /locus_tag="VQ862_001365"
     CDS             complement(5405..5599)
                     /locus_tag="VQ862_001365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001041548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3272 domain-containing protein"
                     /protein_id="HET3115711.1"
                     /translation="MNKQQFIIMALFTAAETYFFNEAWMTGRYIMAAFWAILLFRNFR
                     VSYVMGKIVDVIDQHFNRKD"
     gene            complement(5627..7282)
                     /gene="dnaX"
                     /locus_tag="VQ862_001366"
     CDS             complement(5627..7282)
                     /gene="dnaX"
                     /locus_tag="VQ862_001366"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000283769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit gamma/tau"
                     /protein_id="HET3115712.1"
                     /translation="MYQALYRKYRSQNFSQLVGQEVVAKTLKQAVEQEKISHAYLFSG
                     PRGTGKTSVAKIFAKAMNCPNQVGGEPCNNCYICQAVTDGSLEDVIEMDAASNNGVDE
                     IREIRDKSTYAPSLARYKVYIIDEVHMLSTGAFNALLKTLEEPTQNVVFILATTELHK
                     IPATILSRVQRFEFKSIKTQDIKEHIHYILEKENISSEPEAVEIIARRAEGGMRDALS
                     ILDQALSLTQGNELTTAISEEITGTISLSALDDYVAALSQQDVPKALSCLNLLFDNGK
                     SMTRFVTDLLHYLRDLLIVQTGGENTHHSSVFVENLALPQKNLFEMIRLATVNLADIK
                     SSLQPKIYAEMMTVRLAEIKPEPALSGAVENEIATLRQEVARLKQELSNAGAVPKQVA
                     PAPSRPATGKTVYRVDRNKVQSILQEAVENPDLARQNLIRLQNAWGEVIESLGGPDKA
                     LLVGSQPVAANEHHAILAFESNFNAGQTMKRDNLNTMFGNILSQAAGFSPEILAISME
                     EWKEVRAAFSAKAKSSQTEKEVEESLIPEGFEFLADKVKVEED"
     gene            complement(7282..7779)
                     /locus_tag="VQ862_001367"
     CDS             complement(7282..7779)
                     /locus_tag="VQ862_001367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000920162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GAF domain-containing protein"
                     /protein_id="HET3115713.1"
                     /translation="MLKSEKQSRYQMLNEELSFLLEGETNVLANLSNASALIKSRFPN
                     TVFAGFYLFDGKELVLGPFQGGVSCIRIALGKGVCGEAAHFQETVIVGDVTTYLNYIS
                     CDSLAKSEIVVPMMKNGQLLGVLDLDSSEIEDYDAMDRDYLEQFVAILLEKTTWDFTM
                     FEEKS"
     gene            complement(7865..9067)
                     /gene="rpsA"
                     /locus_tag="VQ862_001368"
     CDS             complement(7865..9067)
                     /gene="rpsA"
                     /locus_tag="VQ862_001368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002897515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S1"
                     /protein_id="HET3115714.1"
                     /translation="MNEFEDLLNSVSQVETGDVVSAEVLTVDATQANVAISGTGVEGV
                     LTLRELTNDRDADINDFVKVGEVLDVLVLRQVVGKDTDTVTYLVSKKRLEARKAWDKL
                     VGREEEVVTVKGTRAVKGGLSVEFEGVRGFIPASMLDTRFVRNAERFVGQEFDTKIKE
                     VNAKENRFILSRREVVEAATAAARAEVFGKLAVGDVVTGKVARITSFGAFIDLGGVDG
                     LVHLTELSHERNVSPKSVVTVGEEIEVKILDLNEEEGRVSLSLKATVPGPWDGVEQKL
                     AKGDVVEGTVKRLTDFGAFVEVLPGIDGLVHVSQISHKRIENPKEALKVGQEVQVKVL
                     EVNADAERVSLSIKALEERPAQEEGQKEEKRAARPRRPRRQEKRDFELPETQTGFSMA
                     DLFGDIEL"
     gene            complement(9229..9300)
                     /locus_tag="VQ862_001369"
     tRNA            complement(9229..9300)
                     /locus_tag="VQ862_001369"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(9266..9268),aa:Gln,seq:ttg)
     gene            complement(9310..9390)
                     /locus_tag="VQ862_001370"
     tRNA            complement(9310..9390)
                     /locus_tag="VQ862_001370"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(9354..9356),aa:Tyr,seq:gta)
     gene            complement(9440..9670)
                     /locus_tag="VQ862_001371"
     CDS             complement(9440..9670)
                     /locus_tag="VQ862_001371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000037109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2969 domain-containing protein"
                     /protein_id="HET3115715.1"
                     /translation="MSKKDKKIEIQVADAKVNVGKDSFEGYTLTIGKKVIGEIAELDG
                     QFAIIKNGNVDSFYKKLEKAVEILIENYNLAK"
     gene            complement(9838..10482)
                     /gene="pcp"
                     /locus_tag="VQ862_001372"
     CDS             complement(9838..10482)
                     /gene="pcp"
                     /locus_tag="VQ862_001372"
                     /EC_number="3.4.19.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HET3115716.1"
                     /translation="MKILVTGFNPFGGEKINPALEAVKLLPSEINGAEVRWVEIPTVF
                     YKSSEVLEAEILRYQPDAVLCIGQAGGRTGLTPERVAINQDDARIPDNEGNQPIDTPI
                     RIDGASAYFSSLPIKAMVQAIKKQGLPAVVSNSAGTFVCNHLMYQALYLVDKKFPNMR
                     AGFMHIPYMMEQVVNKPNTAGMSLCDIVRGIEVAIEAIVDYKDKDLQLVGGETH"
     gene            complement(10497..11420)
                     /locus_tag="VQ862_001373"
     CDS             complement(10497..11420)
                     /locus_tag="VQ862_001373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000137271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF979 domain-containing protein"
                     /protein_id="HET3115717.1"
                     /translation="MTELAKQLLELTYIVIGCQFLHTAYCSYKDKTNPVRLGTSAFWT
                     LLSITFIGGSYMPNMSIGIIVILLSLLTLFKQVRIGTLPSLDEMKANIESNRLKNKIF
                     IPVMLMAILALVLAQMIPEFSKISISLAALFATISVLVITNSHPKSLLSENNRMTQQV
                     STSGIVPQLLGALGAIFTVAGVGDVISHLISGIVPSDSRFIGVLAYVLGMVLFTMIMG
                     NAFAAFTVITAGVGVPFVFALGANPIVAGALAMTAGYCGTLLTPMAANFNALPAALMD
                     MKDQNGVIKAQAGVALVMIVIHIFLMYFLAF"
     gene            complement(11417..12106)
                     /locus_tag="VQ862_001374"
     CDS             complement(11417..12106)
                     /locus_tag="VQ862_001374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000454813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF969 domain-containing protein"
                     /protein_id="HET3115718.1"
                     /translation="MEWIRLIGIAIIVVGFILKFDTIATVVLAGLVTALVSGVSLVEF
                     LEILGKEFSNQRVLTIFMVTLPLVGLSETFGLKQRSIDLIRKIKGLTVGNFYTVYFFI
                     RELAGFFSIRLGGHPQFVRPLVQPMGEAAAESQLGRKLTEVEDETIKARAAANENFGN
                     FFAQNTFVGAGGVLLIGGTLDQLGYESNYAGIASTSIIVAVITLIVVGIYNYLFDKKL
                     ISKKTRGGEQK"
     gene            complement(12171..12875)
                     /locus_tag="VQ862_001375"
     CDS             complement(12171..12875)
                     /locus_tag="VQ862_001375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HET3115719.1"
                     /translation="MVLSTSAILVACGKTDKEADAPTTFSYVYAVDPASLGYSIATRT
                     SRTDVIGNVIDGLMENDKYGNVAPSQKDYDLNGTGWAPSYQDPASYLNIMDPKSGSAM
                     KHLGITKGKDKDVVAKPGLDKYKKLLEDAVSETTDLEKRYEKYAKAQAWSTDSSLLMP
                     TASSGGFPVVSNVVPFSKPYSQVGIKGEPYIFKGMKLQKDIVTTKEYNEVFKKWQKEK
                     LESNSKYQKELEKYIK"
     gene            complement(12931..13953)
                     /locus_tag="VQ862_001376"
     CDS             complement(12931..13953)
                     /locus_tag="VQ862_001376"
                     /EC_number="2.6.1.42"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid aminotransferase"
                     /protein_id="HET3115720.1"
                     /translation="MTVTIDWENLGFSYMKLPYRYLAHFKNGQWDQGELTEDATLHIS
                     ESSPSLHYGQQAFEGLKAYRTKDGSVQLFRPDENAKRLQRTCDRLLMPQVPTDMFVEA
                     CKAVVRANEEYVPPYGTGGTLYLRPLLIGVGDIIGVKPAEEYIFTIFAMPVGNYFKGG
                     LVPTNFLIQDEYDRAAPNGTGAAKVGGNYAASLLPGKMAKSRHFSDVIYLDPSTHTKI
                     EEVGSANFFGITADNEFVTPLSPSILPSITKYSLLYLAEHRLGLTPIEGDVPIDNLDR
                     FVEAGACGTAAVISPIGGIQHGDDFHVFYSETEVGPVTRKLYNELTGIQFGDIEAPEG
                     WIVKVD"
     gene            complement(14085..16556)
                     /gene="parC"
                     /locus_tag="VQ862_001377"
     CDS             complement(14085..16556)
                     /gene="parC"
                     /locus_tag="VQ862_001377"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit A"
                     /protein_id="HET3115721.1"
                     /translation="MSNIQNMSLEDIMGERFGRYSKYIIQDRALPDIRDGLKPVQRRI
                     LYSMNKDSNTFDKSYRKSAKSVGNIMGNFHPHGDSSIYDAMVRMSQNWKNREILVEMH
                     GNNGSMDGDPPAAMRYTEARLSEIAGYLLQDIEKNTVPFAWNFDDTEKEPTVLPAAFP
                     NLLVNGSTGISAGYATDIPPHNLAEVIDAAVYMIDHPTAKIDKLMEFLPGPDFPTGAI
                     IQGRDEIKKAYETGKGRVVVRSKTEIEKLKGGKEQIVITEIPYEINKANLVKKIDDVR
                     VNNKVAGIAEVRDESDRDGLRIAIELKKDANTELVLNYLFKYTDLQINYNFNMVAIDN
                     FTPRQVGIVPILSSYIAHRREVILARSRFDKEKAEKRLHIVEGLIRVISILDEVIALI
                     RASENKADAKENLKVSYDFTEEQAEAIVTLQLYRLTNTDVVVLQEEEAELREKIAMLA
                     AIIGDERTMYNLMKKELREVKKKFATPRLSSLEDTAKAIEIDTASLIAEEDTYVSVTK
                     AGYIKRTSPRSFAASTLEEIGKRDDDRLIFVQSAKTTQHLLMFTSLGNVIYRPIHELA
                     DIRWKDIGEHLSQTITNFETNEEILYVEVLDQFDDATTYFAVTRLGQIKRVERKEFTP
                     WRTYRSKSVKYAKLKDDTDQIVVVAPIKLDDVVLVSQNGYALRFNIEEVPVVGAKAAG
                     VKAMNLKEDDVLQSGFICNTSSFYLLTQRGSLKRVSIEEILATSRAKRGLQVLRELKN
                     KPHRVFLAGAVAEQGFVGDFFSTEVDVNDQTLLVQSNKGTIYESRLQDLNLSERTSNG
                     SFISDTISDEEVFDAYLQEVVTEDK"
     gene            complement(16976..18919)
                     /gene="parE"
                     /locus_tag="VQ862_001378"
     CDS             complement(16976..18919)
                     /gene="parE"
                     /locus_tag="VQ862_001378"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit B"
                     /protein_id="HET3115722.1"
                     /translation="MSKKEININNYNDDAIQVLEGLDAVRKRPGMYIGSTDGAGLHHL
                     VWEIVDNAVDEALSGFGDRIDVTINKDGSLTVQDHGRGMPTGMHAMGIPTVEVIFTIL
                     HAGGKFGQGGYKTSGGLHGVGSSVVNALSSWLEVEITRDGAVYKQRFENGGKPVTTLK
                     KIGTAPKSKTGTKVTFMPDATIFSTTDFKYNTISERLNESAFLLKNVTLSLTDKRTDE
                     AIEFHYENGVQDFVSYLNEDKEILTPVLYFEGEDNGFQVEVALQYNDGFSDNILSFVN
                     NVRTKDGGTHETGLKSAITKVMNDYARKTGLLKEKDKNLEGSDYREGLAAVLSILVPE
                     EHLQFEGQTKDKLGSPLARPVVDGIVADKLTFFLMENGELASNLIRKAIKARDAREAA
                     RKARDESRNGKKNKKDKGLLSGKLTPAQSKNPAKNELYLVEGDSAGGSAKQGRDRKFQ
                     AILPLRGKVINTAKAKMADILKNEEINTMIYTIGAGVGADFSIEDANYDKIIIMTDAD
                     TDGAHIQTLLLTFFYRYMRPLVEAGHVYIALPPLYKMSKGKGKKEEVAYAWTDGELEE
                     LRKQFGKGATLQRYKGLGEMNADQLWETTMNPETRTLIRVTIEDLARAERRVNVLMGD
                     KVEPRRKWIEDNVKFTLEEATVF"
     gene            19055..19696
                     /gene="plsY"
                     /locus_tag="VQ862_001379"
     CDS             19055..19696
                     /gene="plsY"
                     /locus_tag="VQ862_001379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000628793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate 1-O-acyltransferase PlsY"
                     /protein_id="HET3115723.1"
                     /translation="MITIVLLILAYLLGSIPSGLWIGQVFFQINLREHGSGNTGTTNT
                     FRILGKKAGMATFVIDFFKGTLATLLPIIFHLQGVSPLIFGLLAVIGHTFPIFAGFKG
                     GKAVATSAGVIFGFAPIFCLYLAIIFFGALYLGSMISLSSVTASIAAVIGVLLFPLFG
                     FILSNYDSLFIAIILALASLIIIRHKDNIARIKNKTENLVPWGLNLTHQDPKK"
     gene            complement(19741..>20010)
                     /locus_tag="VQ862_001380"
     CDS             complement(19741..>20010)
                     /locus_tag="VQ862_001380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET3115724.1"
                     /translation="QHDSYHRFLESKGIQASMSRKGNSQDNGMMESFFGILKSEMFYG
                     YEKSFQSLKQLEQAIIDYIDYYNNKRIKVKLKGLSPVQYRTKSFG"
BASE COUNT         5749 a         4546 c         3605 g         6110 t
ORIGIN      
        1 atacatacga taaggcgatg ctgacgtggt ttgaagagat tttcgaagag tataaaatca
       61 aattttatcc aactgatccc tccatttcat agctaatcaa gcggttcagc tcaactgcgt
      121 attccattgg aagttctttt gtaaagggtt ctacaaatcc catgacaatc atttcagttg
      181 cctcagattc tgacaatcca cggctcatga gataatacaa ttgctcttct gaaatcttag
      241 atactttggc ttcgtgttcc aaagccactt gcgagttgtg aatttcatta aatggaatag
      301 tatctgatgc tgacaagtca tccatgataa tggtatcaca ttcaatgtgg gaaacagatt
      361 tcttagagtt cttgttaaag gtgacttgtc cacggtagtc aacctttcct ccacctttag
      421 cgatggattt agacacaata gacgagctgg tatgtggagc attgtgaatc atcttagcac
      481 ccgtgtcttg gtgttgccct gcattagcaa aggcgataga gagcatggta ccacgcgctc
      541 cttctccatc aaggtaaaca gatggatatt tcatagtcgt tttggcaccc aagtttccat
      601 caatccactc aacagtggca tccttttgag ccttagcacg ctttgttacc aagttataga
      661 cgttatcaga ccagttttgg atagttgtat aacgcatata agctccgtcc aaagcaaaaa
      721 tttctacaat ggcagcgtgt aagctattgc ttgaatatgt tggtgctgta catccttcta
      781 cgtagtggac gcttgctccc tcatcaacga taatcaaggt acgttcgaac tgacctatat
      841 tttcgttatt gatacggaaa taagtttgaa gtggaatatc taccttgaca ccttttggca
      901 cgtagataaa agttccaccc gaccatactg ctgagttgag ggctgccaac ttgttatctg
      961 tcggcggtac caacttcgca aagtattgat taaataagtc tgggtattcc ttgagtgcgg
     1021 aatctgtatc tgtaaagata atacctaatt tttggaactc ttccttcatg ttgtggtaaa
     1081 ccacttctga ctcgtactgg gcagaagccc ctgctaaata agcacgttca gcttctggaa
     1141 tcccgatacg ttcaaaggtt tctttaatct tttcaggtac atcatcccaa gaacgggctg
     1201 gtttgtcaga tggtttttgg tagtagatta agtcatcaaa gtcaatctct gacaagtctg
     1261 ctccccaagt ttgcatgggc atttttttga aggtttcata agacttcaaa cggaactcca
     1321 acatccactc aggctcaccc ttagcagcag ataattcacg aataacacct tcgttgagtc
     1381 cttttcctgt cgataagaca ggctctacat cgtcatggaa accaaattta tattcaccaa
     1441 ggtcaattgg ttttggttct actctttctt cagccataat atcctttctt tcttcatttc
     1501 taataattca taagacaaaa gaaacttgtc ttactgtttt tcttgatttt caattgtttt
     1561 cttaagggca ttccaagcta gggttgcaca cttgattctt tgagggaatt tggcaacacc
     1621 tgacaagaat gccgcgtctc caagttggtc ttgacgctca tctttttgcc cttgaaccat
     1681 ttcagaaaaa atagtcgcca gttctaaaat ttcttgtttg gtttttccta aaacggcatc
     1741 tgtcatcata ctagcagaag cagttgaaat cgtgcatcct gaatttagaa aagcaatatc
     1801 ttccaaacgg tcctctgcat caaacttgac agagagattg atgacatctc cacaagtcgg
     1861 attgttgaga ctgatttgct cagcgtcttc taacttccct tggtgatgtg gatttttcga
     1921 atggtctgct accactgcca tataaaggct atctagttta gaaagtgcca ttgaaaaact
     1981 cctttgtctt ttgtagggca tcgactagtt tgtcgcaatc tgccttggta ttatagatat
     2041 aaaaacttgc acgagctgtt gctgagactt ccaaatactg aagcaagggt tgcgcacaat
     2101 ggtgaccagc acgaacagcc actccttcat aatccagagc cgtcgcaaga tcgtgaggat
     2161 ggagatcacc taggttaaag gcaataacac ccgaacgttg agccaaatcc tgagaaccgt
     2221 aaatggtcaa tccctcaatt gcctgcagtt ttggatagac gtacgcaatc aattcctgtt
     2281 catgagcttc aacggcatcc ataccaatct tttccagata atcaactgca gtcgcaagtc
     2341 caatagctcc tgccatattt ggcgttccag cctcaaattt ccaaggcaat tccttccaac
     2401 tagcggattg ctcgtagaca aaatcaatca tctcgccgcc aaattctact ggagacattt
     2461 gctcaagata cttttctttg ccgtaaagga caccgatacc agtcggacca gccatcttgt
     2521 gacccgaaaa ggcgaaaaag tccagatcca agtcctggac atcaatcttc atatgaggtg
     2581 tagattgagc accatccact accatgattg ccccaacttg gtgggctaat tgagtgattt
     2641 ccttgatcgg attgaccaca ccaagaacat tggaggcatg agctagggaa acaaatttaa
     2701 ccttatcagt caatttagct cgcaaatcct ccatatccaa ggcaccgtct ttaagataga
     2761 catagacaag ctctgctcca gtctttcgac aagcttcctg ccatggaatg atattagaat
     2821 ggtgttccat tactgaaatc aagacctggt ctccctcagt gagaatttcc tcagcaaagc
     2881 gtgccaccca gttaaggctg gttgtcgttc ctctggtaaa gagaacttcc tttgtagagc
     2941 ctgcattaat aaacttacga atggtttcac gagcagcttc ataagaagct gtcgctcgtt
     3001 ccgctaaggt atggacacca cggtgaacat tggcattgtc ctgctcatag taactgttaa
     3061 tagctttcag aactactagt ggtttttgtg tcgtcgcagc attgtccaga tagaccagag
     3121 gttcatcatt gacaatctga tctaaaattg gaaaatcctt gcgaatcgct tctacatcta
     3181 acataggctt ccccttagcg ttttgacaat ttctcttcga tagttgcaat catttcatca
     3241 cgaacttcct tgactggaat ctccacgata acagatccaa ggaaaccacg aacaaccaaa
     3301 cgctctgcag ttgccttatc caatccacga ctcatgaggt aatacatgtc ttctggatca
     3361 acttgtccga tagacgctgc gtgtcctgca gtgacatcat tttcatcaat caaaagaatt
     3421 gggttagcat ctgaacgcgc ttggtctgaa agcatgagaa cacggctctc ttgttgggca
     3481 tctgctccct tagcaccctt gatgatgtgg ccgataccat tgaaagtcaa agttgctttt
     3541 tcaaggataa ccccatgttg taggatattt ccgatagagt tgcagccata gttagttaca
     3601 cgagtatcaa tcccttgtac ctgacgacca cttgaaagag ctacaacctt gaggtcagca
     3661 tagctaccat taccaatcaa gtcactatca aaatcagcaa cgacatttcc ttcgttcatg
     3721 acaccgatag cccagtcaat acttgcatcg ttgcctaatt taccacgacg gctaatgtag
     3781 gcagtgacgt tttcacctag acggtcgata gcagcaaact tgacttgcgc accagaatgt
     3841 gcaatcactt ccactgtgat attggcagtt gctttgtcac ttccttcacc gcgtgactct
     3901 aaacgctcca gataactaat cttagaattt ttaccagcga taatcataat atgcttgtta
     3961 aacggcacat tgctatcgct atcttggtag aaaattcctt caattggctc tgtgatttct
     4021 acgttatctg gaatatagag tacagcacca ctgttaaagt aagctgtgtg gtaagccgcc
     4081 aacttgtcat catcatactt aacagatgac atgaagaatt cttcgatcag ctctggaatt
     4141 tcttctaaag ctgagtgaaa gtctgtgaag acaacaccct gttcagctaa ctcaactgga
     4201 gtttgttcga aaacagtttg agttcctact tgcaccaact tcaagtgatg atctaaagct
     4261 gtgaaatctg gaacatttgc tgatggctca ttttctgtaa tcgttccatc acccagattc
     4321 caacggtgga atttgacacg ctcaataact ggtaattcca aagtctcaat cttgtcaaaa
     4381 gctttttgac ggagatcagc caaccagctt ggttcagcgt gcatttctga aaaaagttta
     4441 atattttctc tagtcattta cttctcctaa aagatacgag gaaattacaa ttcttccttg
     4501 tagtcgtagc caagttcttc agctaatttt gcgtatcctt cacgttccaa acgcgcagcc
     4561 aattctggac caccagaaag gacaacacga ccttccatca tcacgtgtac cacatcaggt
     4621 gtgatatagt tcaaaagacg ttggtagtga gtgatgatca tagcaccaaa accttcacca
     4681 cgcatggcat tgacaccttt agacacaact ttaagagcgt caatatcaag acctgagtca
     4741 atctcgtcca aaagagcaaa tgttggctcc aacatcaaaa gttgaagaat ttcattgcgt
     4801 tttttctcac caccagagaa gccttcgttg aggtaacgct ctgccatttc ttctttcatg
     4861 ttgagcaatt ccattttttc atctagctta gtaataaact cacgaactga aatcttctca
     4921 tcatcttctt tacccgcatt catagcggca cgaagaaact cagcattggt aattccaggg
     4981 atttctgatg ggtattgcat agcaaggaaa agtcccatac gcgcacgctc atccacttcc
     5041 aactcaagga tgtttacgcc atcaaacaaa acttcacctt tagttacttc atagtttgga
     5101 tttcccatga tagcggcaga aagagtcgat ttacctgtac catttggtcc catgatagcg
     5161 gcaatttctc ctgttttcag ggtcaggtta acccctttta aaatttcttt tccttcaatc
     5221 tcaacgtgaa gatctttgat ctctattact gacatgatag ttcctttctt tttcaaaact
     5281 tttacagtac ttactagaaa aacgtctgat ttccccagaa atagagcaaa aattctataa
     5341 atatactttt ctagtataac aaaaaaaagc ctaaaaggct ttgattttgt ctggaagctg
     5401 agggctagtc tttcctatta aaatgctgat cgatgacatc aacaatttta cccatcacat
     5461 aactgactcg gaaatttcta aagagtaaaa ttgcccaaaa ggctgccata atatagcggc
     5521 cagtcatcca ggcttcattg aaaaaatagg tctcagcagc tgtaaatagc gccataataa
     5581 taaattgttg tttattcata aacttattgt atcatgaaat ctttctttag tcttcctcta
     5641 ccttcacttt atcagccaaa aattcaaatc cttctggaat caggctttct tctacttctt
     5701 tttcagtttg agaagatttg gctttggctg aaaaggctgc gcgaacttct ttccattcct
     5761 ccatggaaat agctaaaatc tcaggtgaaa aacctgccgc ctgactgagg atattaccaa
     5821 acatggtatt gagattgtct cgtttcatag tttgaccagc attgaagtta gactcaaaag
     5881 caagaatagc atggtgttca ttggcagcaa ccggttgaga accaactagc agagccttgt
     5941 ccggcccacc tagactttca attacctctc cccaggcatt ctgcaaacga attagatttt
     6001 gacgtgctaa atcaggattt tcgacggcct cttgtaagat agattgcact ttattgcgat
     6061 cgacacgata gactgttttg cccgtagctg gtcgactagg agctggtgca acttgtttag
     6121 gaaccgcacc tgcattagaa agctcttgtt tgagacgggc aacttcctgt ctcagcgtag
     6181 caatttcatt ttcaaccgct cctgatagag ctggttcggg cttgatttcc gccaaacgga
     6241 cggtcatcat ttcagcataa atcttgggct gcaaactaga cttaatatct gctaaattca
     6301 ctgttgctaa gcgaatcatt tcaaacagat ttttttgagg aagtgccaaa ttttctacaa
     6361 agactgaact atgatgagta ttttctcccc ctgtttgaac aattaacaag tctcttaaat
     6421 agtgcaaaag atcggtcaca aaacgagtca tgctcttacc attgtcaaaa agaagattca
     6481 agcaagacaa agctttggga acatcctgtt gagacaaggc cgccacataa tcatccaagg
     6541 ctgataggct aatggtgcca gtaatttctt cagagatagc agtcgtcagc tcatttccct
     6601 gtgtcaaact cagggcttga tccaaaatag acaaggcgtc ccgcattcca ccttccgccc
     6661 gtctggcaat gatttccaca gcctctggtt cagaactgat attttctttt tctaagatat
     6721 agtgaatatg ttccttaata tcctgtgtct taattgattt aaactcaaaa cgttgcacac
     6781 gggatagaat agtagcagga atcttgtgca attcagtagt ggccaaaata aagactacat
     6841 tctgtgttgg ctcttccagc gtctttagga gggcattaaa agcccctgta gacagcatgt
     6901 gaacctcatc tatgatataa accttataac gagcaaggct aggcgcatag gtagatttat
     6961 cacgaatttc gcgaatttca tctaccccat tattagaagc tgcatccatt tcaatgacat
     7021 cttctaaact accgtccgtc actgcttgac aaatatagca gttattgcaa ggttcgccac
     7081 ccacttgatt gggacagttc atagccttgg caaagatttt agcaacactg gtttttcccg
     7141 ttccacgagg accagaaaaa agataagcgt gacttatttt ctcttgctcc accgcttgtt
     7201 taagagtctt agccacaact tcttgaccaa ctaactggga gaagttttga cttctatatt
     7261 ttcgataaag tgcttgatac attaagattt ttcctcaaac atcgtaaagt cccatgttgt
     7321 cttttcaagc aaaatagcga caaattgttc caaataatct cgatccatag catcgtaatc
     7381 ctcaatctct gaagaatcca gatccagaac tccaagtaac tgaccattct tcatcatcgg
     7441 caccacaatt tcacttttag ctagactatc acaagaaata tagttgagat aggtcgtcac
     7501 atctccaaca ataacagttt cctgaaagtg agctgcctca ccacaaacac ccttgcctag
     7561 tgcaatacgg atgcaggaaa cacctccttg gaagggacct aaaaccaatt cctttccatc
     7621 gaacaaataa aagcctgcaa atacggtatt aggaaaacgt gattttataa gagcactggc
     7681 gttggaaaga ttagccaaaa cattggtttc gccttccaat aggaaggaca attcttcatt
     7741 taacatttga taacgtgatt gtttttctga ttttaacata gaactattat atcaaaaaag
     7801 gagcagagac aaaagaaaaa tcccttgttt agtaaacaaa ggattttgtg aattttcaat
     7861 ttgattaaag ttcgatatca ccaaacaaat cagccattga aaatcctgtt tgtgtttctg
     7921 gaagttcgaa atcacgcttt tcttgacgtc ttggacgacg tggacgagca gcacgttttt
     7981 cttctttttg tccttcttct tgggctggac gttcttcaag agctttaata gaaagtgaca
     8041 cgcgttctgc atctgcgtta acttcaagaa ctttaacttg aacttcttga ccaactttaa
     8101 gagcttcttt tggattttca atccgcttgt gtgaaatttg tgatacgtga acaagtccat
     8161 cgatacctgg caatacttca acaaatgcac cgaagtcagt caaacgttta actgttcctt
     8221 ctactacatc acctttagcc aatttttgct caacgccatc ccatggtcct ggtactgttg
     8281 ctttaagtga aagtgataca cgtccttctt cttcgttaag atcaaggatt ttcacttcaa
     8341 tttcttcacc aacagttaca actgattttg gtgatacgtt acgttcatgt gacaattcag
     8401 tcaagtgaac caatccgtca acaccaccaa ggtcgatgaa agcgccgaag cttgtgatac
     8461 gagcaacttt accagttaca acatcaccaa cagccaattt accgaatact tcagcgcgag
     8521 ctgctgcagt agctgcttca acaacttcac gacgtgaaag gatgaagcgg ttttctttag
     8581 cgttaacttc tttgatttta gtatcaaatt cttgacctac aaaacgctca gcgttacgta
     8641 cgaaacgagt atccaacatt gaagctggga taaatccacg aacaccttca aattctactg
     8701 aaagtccacc tttaacggca cgcgttcctt taacagtaac aacttcttct tcgcgaccaa
     8761 caagtttgtc ccatgctttg cgagcttcaa ggcgtttttt agatacaagg tatgtaactg
     8821 tatcagtatc tttaccaact acttgacgaa gtacaagaac atccaatact tctcctactt
     8881 taacaaagtc attgatatct gcatcacgat cgtttgtcaa ttcgcgaaga gtcaagacac
     8941 cttcaacacc agttccagag attgcaacgt tagcttgagt cgcatcaact gtcaatactt
     9001 cagcactaac aacatcacca gtctcaactt gactaacgct atttagcaaa tcttcaaatt
     9061 cgttcatcta aaaaatcctc caacaatcaa gtttttctta aacttgacat acttataatt
     9121 tttttcctaa gcacccgcaa ggacatgttc atatcattca cgtctttcaa ttataaaaat
     9181 aaaataccct aagatatttt gctttttatc ttgattatta cctaagaact ggggtagctg
     9241 gattcgaacc aacgcatgag ggagtcaaag tcccttgcct taccgcttgg ctatacccca
     9301 ttaatgaaat ggagagagag ggattcgaac ccccgaaccc gaaggagcgg atttacagtc
     9361 cgccgcgttt agcctcttcg ctatctctcc tacaatcaac atggactatt atatcatgaa
     9421 aatttcaaaa aaacaagact tattttgcta aattataatt ttcaatcaaa atttccacag
     9481 ctttttccaa ttttttataa aaactatcga cattcccatt ctttataatg gcaaattgtc
     9541 cgtctaattc ggcaatttct ccgataactt ttttaccgat agtcaatgta taaccttcaa
     9601 aactgtcttt accaacatta actttggcat ccgctacttg aatttcgatt tttttatctt
     9661 tcttgctcat ttcatacctc tcttcacttt ttctatttta caagaaaatc ctaaaactag
     9721 caagaaaaaa ctctatatca ggcttctctg atatagagtt ttatgtaaac aacctcaatt
     9781 gatttagcat agttaatagt tagtaaacaa gcataattga ctatcctttt taggttatca
     9841 gtgagtctca ccgcctacta actgcaaatc cttatctttg tagtctacaa tagcttcaat
     9901 agctacctct atgcctctta caatatcaca tagactcatt cctgcagtat tcggcttatt
     9961 tactacttgt tccatcatat atggaatatg catgaaacct gctctcatat tagggaattt
    10021 tttatccact aaataaagag cttggtacat caaatgattg caaacaaagg ttcctgcact
    10081 attggataca actgccggaa gtccctgttt tttgatagct tgtaccatcg ctttgatagg
    10141 taaactacta aaataggccg atgctccatc aatacgaatc ggtgtatcaa ttggttgatt
    10201 gccttcgtta tcaggtatgc gagcatcatc ttgattaata gccactcgtt caggtgttaa
    10261 gccggtcctg ccgcctgctt gtccaataca aagtacagca tctggttgat atcgtaatat
    10321 ttctgcctct aaaacttctg acgacttata aaaaaccgtt ggaatttcta cccagcgaac
    10381 ttcagcccca ttaatctcag atggtaataa ttttacagcc tccaaagctg gattaatctt
    10441 ttcacctcca aaaggattaa aacctgtaac caatattttc attttatttt cctttactaa
    10501 aatgcgagaa agtacattaa gaatatgtga ataacaatca ttactagagc aacacctgct
    10561 tgagccttta taacgccatt ctgatctttc atatccatca atgctgctgg tagagcgtta
    10621 aaattagcag ccattggggt caataaggtc ccacaataac ctgctgtcat ggcaagagca
    10681 ccagccacaa ttggattagc tcccagagca aatacaaagg gaactccaac acctgctgta
    10741 ataacggtga atgctgcaaa agcatttccc ataatcattg tgaatagaac cattccaaga
    10801 acataagcca aaactcctat aaagcgacta tctgaaggaa caataccgct aatcagatga
    10861 gagataacat caccaacacc tgctacagta aaaatagccc ccaaagcccc taataattga
    10921 ggaacaatac cacttgttga aacttgctga gtcattcgat tattttctga taacagactc
    10981 ttagggtgac tattggtaat cacaagaaca gaaattgtag caaacaaggc ggcaaggcta
    11041 atcgaaatct tgctaaattc tggaatcatt tgcgctaaga ccaacgcaag tattgccatc
    11101 agcataactg gaataaaaat tttatttttc aacctgttag attcaatatt ggctttcatt
    11161 tcatctaagg atggcaaggt tccgatacgg acttgcttaa acaatgttaa cagcgataat
    11221 aggattacaa taataccaat actcatattt ggcatatagg aaccacctat aaacgtaata
    11281 gacaatagag tccaaaatgc agatgtccca agtcgaactg ggtttgtttt atctttataa
    11341 ctacaatagg ctgtatggag aaattgacaa ccaatcacaa tataggtcaa ctctaatagt
    11401 tgctttgcca actctgtcat ttttgttctc ctcccctagt cttttttgat atcaattttt
    11461 tatcaaataa ataattgtaa atccccacta caataagtgt tataacagca acaataatag
    11521 atgtagaagc aatccctgca taattgcttt catagcctaa ctgatctaat gttcccccta
    11581 tcaagaggac tcccccagca cctacaaacg tattttgagc aaagaaattt ccaaaatttt
    11641 cattcgcagc cgcacgcgct tttattgtct catcttcaac ctctgttaac tttctaccta
    11701 attgagactc tgcagctgct tctcccatag gttgaaccaa aggtctgaca aactgagggt
    11761 gtcctcctag acgaattgaa aagaaaccag ctaactctcg aataaagaaa taaactgtat
    11821 agaagtttcc aactgtcaga cctttaatct ttcgaatcaa atcgattgat cgttgcttga
    11881 gtccaaaggt ttctgacagc cccacaagag gcaaggtaac cataaaaatc gtgagcactc
    11941 gctgattgct aaattctttt cccaaaatct ccaaaaattc aacgagagaa acacctgaaa
    12001 ctaaagctgt aaccaaacca gctaagacta ctgttgcaat tgtatcaaat tttaaaataa
    12061 aacccacaac aatgattgct attcctatta atctaatcca ctccatatca aactccttta
    12121 tattcaaaat gacagtattt taaaaatttt atcaagatca ataccattcc ttatttaatg
    12181 tatttttcta gttctttttg gtatttgcta ttggattcca atttttcttt ttgccatttt
    12241 ttaaaaacct cgttatattc ttttgttgta acaatatctt tttgcaattt cattccttta
    12301 aagatatatg gttccccctt aataccaact tgtgagtatg gttttgagaa tggtactacg
    12361 ttacttacaa ctggaaaacc accagatgaa gctgttggca tcaataatga actatctgtc
    12421 gaccaagctt gagctttggc atatttttca tatctcttct ctaggtcagt ggtctcagaa
    12481 acagcatctt ctaacaattt cttatattta tccaaaccag gtttagctac aacatcctta
    12541 tcttttcctt tcgtaatgcc aaggtgtttc atggcagaac cagattttgg atccataata
    12601 ttcaagtaag acgctggatc ttgatagctt ggagcccatc ctgtaccgtt caaatcatag
    12661 tctttttgag aaggagcaac attgccgtat ttatcatttt ccatcaaacc atcaataaca
    12721 tttccaataa cgtctgtcct cgatgttcga gtcgctatac tgtagcccaa tgatgctgga
    12781 tctactgcat agacataaga aaatgttgtc ggtgcatctg cttctttatc agtttttcca
    12841 caagccacta aaatagctga cgtgctcagg accactcctg ctgttaagag ccactttttc
    12901 tatttcataa aaaatctcct ttggtttatt ttaatctact tttacaatcc aaccttctgg
    12961 cgcttcaata tcgccaaact gaatacccgt caattcatta tataatttac gcgtcacagg
    13021 acctacttct gtttcactat agaatacatg gaaatcatca ccatgttgaa tacctccaat
    13081 tggagaaata accgctgctg taccacaggc acctgcctct acaaaacggt caagattatc
    13141 aattggaaca tcaccctcaa taggagttaa tcccaagcga tgttctgcca aataaagcaa
    13201 ggaatacttg gtaatagatg gcaagataga tggactcaat ggtgttacaa attcattatc
    13261 agctgtaatt ccaaagaagt tagctgatcc gacttcttca atctttgtat gagttgatgg
    13321 gtccagatag ataacatctg agaaatgacg tgacttggcc atttttcctg gtaagagact
    13381 tgcagcatag tttccaccaa ccttagccgc acctgtacca tttggtgctg cacggtcgta
    13441 ctcatcctga atcaagaagt tggttgggac caaaccacct ttaaagtaat ttccaactgg
    13501 catagcaaag atggtgaaaa tgtactcttc tgccggtttt accccgataa tatctccgac
    13561 accaatcaaa agagggcgaa gatataaggt tccacctgtt ccgtatggtg gtacgtattc
    13621 ttcattcgca cggacaactg ctttacaagc ttctacaaac atgtctgtcg gaacttgtgg
    13681 catcaagaga cggtcacatg tacgttgcag acgtttagca ttttcatcag gacggaacag
    13741 ttgaacactg ccatccttag tacgataagc tttcaaacct tcaaatgctt gttgtccata
    13801 gtgaagactt ggagaagact ctgaaatatg caaagttgca tcctctgtaa gctctccttg
    13861 atcccattgt ccatttttga aatgagcaag atagcgataa ggtaatttca tataggaaaa
    13921 accgaggttt tcccaatcaa tcgttactgt catattccac tccttattct aaaaacctat
    13981 ttcttatatt ctacactatt tttctaaaat agcaagtata ttttgtaatt ttcagaaaat
    14041 ttctccaata aaaaccagct cttagaactg attcttcatt tcacttattt atcttcagta
    14101 actacttcct gaagataagc gtcaaaaact tcttcatctg aaatcgtgtc agaaatgaag
    14161 cttccattgc tagtgcgttc tgacaagttc aagtcttgca atcggctttc atagattgtt
    14221 cctttattgg attggacaag cagagtttgg tcgttcacat ccacttccgt actgaagaaa
    14281 tcgccaacaa atccttgctc tgcaactgct cctgccaaga agacacgatg cggtttgttt
    14341 ttcaactcac gcaagacttg taatcctcgt ttggcacggc tggttgctag aatttcctca
    14401 atagaaacac gtttcaagct tccacgctgg gtcaagaggt agaaggacga agtattacag
    14461 ataaagccag attggaggac atcatcttct ttcaaattca tagccttgac acctgctgcc
    14521 ttagcaccga caaccggaac ctcttcgata ttgaaacgca gggcataacc attttgacta
    14581 accaagacaa catcatctag tttaatcgga gccactacta caatctgatc tgtatcgtct
    14641 ttgagcttag catacttgac agacttagat ctataggtcc gccatggagt gaattctttt
    14701 cgctctaccc gtttgatttg accaaggcga gtcactgcaa agtaggttgt cgcatcgtca
    14761 aactgatcca gtacttccac ataaaggatt tcttcattcg tttcaaagtt tgtgatggtt
    14821 tggctcagat gctctccgat gtccttccaa cgaatatctg ccaactcatg gattggtctg
    14881 tagatgacat ttccaagact tgtgaacatc aagaggtgct gggttgtctt ggcagattga
    14941 acaaaaatca aacggtcatc atcacgcttg ccaatttctt ccaaggtgga agccgcaaag
    15001 gaacgtggac tggtacgctt gatgtaacct gccttggtca cgctgacgta ggtatcttcc
    15061 tcagcgataa gactagctgt atcaatctca attgctttcg cagtgtcttc taaagaactc
    15121 aaacgaggag ttgcaaattt cttcttgacc tcacgaagtt ctttcttcat gagattgtac
    15181 atagtccttt catcaccgat aatagccgcc agcatagcaa tcttctcacg aagctctgct
    15241 tcttcttcct gcaagacaac cacatcggta ttggtcaaac ggtacagttg caaagttacg
    15301 atagcctcag cctgttcttc cgtaaaatca tagctaactt tgaggttttc cttggcgtcc
    15361 gccttattct cagaagcacg gataagagca atgacttcat ccaaaatcga aatcacacga
    15421 atcaaacctt cgacgatatg gagacgtttc tcagcctttt ctttgtcaaa gcgtgaacgc
    15481 gccaaaatca cttctcgacg gtgagcgatg tagctagaca ggattggaac aatcccaacc
    15541 tgacgaggtg tgaaattgtc aatcgccacc atattaaagt tgtagttgat ttgtaggtcg
    15601 gtgtacttaa ataagtagtt gagaacaagc tcagtattag cgtctttctt aagttcgata
    15661 gcgatacgaa gaccatcacg gtcagactca tcacgaacct cagcaatccc agctaccttg
    15721 ttattaacac gaacatcatc gattttcttg actagattgg ccttattgat ttcataagga
    15781 atctcagtaa taacgatttg ttccttacca ccttttagct tttcaatttc agtcttggaa
    15841 cgaacaacca cgcgcccttt cccagtctca taagctttct tgatttcatc acgaccctga
    15901 ataatagccc ctgtagggaa gtctggtcca ggcaagaatt ccatgagttt atcaatcttt
    15961 gcagttgggt ggtcaatcat gtaaactgca gcatctatga cctcagctaa attatgggga
    16021 ggaatgtctg tggcataacc agccgaaatc ccagtcgaac cattgaccaa gaggtttgga
    16081 aaggctgctg gcaagaccgt tggttctttc tccgtatcgt caaagttcca tgcaaaagga
    16141 actgtatttt tctcgatatc ctgaagaagg taacctgcaa tttcagacaa acgtgcctca
    16201 gtataacgca tagccgcagg aggatctccg tccatagaac cgttattacc gtgcatttca
    16261 actagaatct cacgattttt ccagttctgt gacatacgaa ccatggcatc atagatagaa
    16321 gaatccccgt gtgggtggaa attccccatg atgttcccga ctgacttggc cgacttacgg
    16381 tagctcttgt caaaagtatt gctatcctta ttcatagaat aaagaatacg gcgctgaacc
    16441 ggcttcaacc catcacgaat atctggcaaa gcccggtctt gaataatgta cttggagtag
    16501 cgaccaaagc gctctcccat gatgtcctcc agggacatgt tttgaatgtt agacataaga
    16561 tacaaagccc ataaaatacc aagtgaaaat agaaaattct tgaagtaagc aaactcacaa
    16621 gagaatttat ctttttcaca cagtatctag ggcgtgttca actcctttca aagaatgtag
    16681 agtaggtttt tatgcagtaa aagatatttt acgggaattc ctcccgtgtt cagttacgat
    16741 aagtaaccaa actatcctgt ttgtattttt caatatgaaa atctggtttt ccaaaattag
    16801 tcttagtttg tgtcttagcc gctcccttaa gcgcctcttt gagataagca ctcatagcag
    16861 attcttcatt aataatcctg caattttttc aaaccaagat tttcaaactg ctttttcaca
    16921 tagtcattca catccgactc taatttccag tttactaaca tattattttc tttcattaaa
    16981 acactgtcgc ttcttctagc gtaaacttga cattatcttc aatccattta cggcgtggtt
    17041 ctaccttatc tcccatgaga acattgacgc ggcgttcggc gcgcgctaaa tcttcaattg
    17101 tgacacggat gagggtacgt gtttctgggt tcatggttgt ttcccagagc tggtccgcat
    17161 tcatctcacc aagtcctttg tatcgttgga gggtagcgcc tttaccgaac tgtttacgga
    17221 gttcttctag ttctccgtcc gtccaagcgt aggccacttc ttctttcttt cctttacctt
    17281 tggacatctt gtaaagaggt gggagggcaa tatagacatg acctgcctcg actagcggac
    17341 gcatgtaacg gtagaaaaat gtcaagagca aggtctggat atgggcaccg tcggtatccg
    17401 catcggtcat gataatgatc ttatcatagt tggcatcttc aatagagaag tctgctccaa
    17461 cacccgcacc aatggtataa atcatggtat tgatctcttc atttttgagg atatccgcca
    17521 tcttggcctt ggctgtattg ataaccttac cacgaagagg tagaatagcc tggaacttgc
    17581 ggtcacgacc ttgtttggca gaaccaccgg cagagtcccc ctcaactaga tagagttcat
    17641 tcttagcagg attcttagat tgggctgggg tcaatttccc agacaacaag cccttatctt
    17701 tcttgttttt cttcccattt cggctctcat cacgcgcctt acgtgctgct tcacgagcat
    17761 cacgggcctt gatagccttg cggatgaggt tagaagctaa ttccccattt tccataagga
    17821 aaaaggtcaa cttatcagcc actattccat ccacaactgg gcgagctagg gggcttccta
    17881 gtttatcctt ggtctgtcct tcaaactgca agtgttcttc aggaactaag atagaaagaa
    17941 cggccgctag tccctcacga tagtctgaac cttcaaggtt tttatctttt tccttgagaa
    18001 gacctgtttt acgtgcatag tcattcatga ccttggtaat ggcagacttg agtcctgtct
    18061 cgtgcgttcc accgtccttg gtgcgaacgt tattgacaaa ggatagaatg ttatctgaga
    18121 atccgtcatt gtactggagg gctacttcca cttgaaaacc attgtcttcc ccttcaaagt
    18181 aaagaactgg cgtcaagatt tccttatctt cgttgagata agaaacaaaa tcttgtactc
    18241 cattctcata gtggaactca atcgcttcat ctgttcgctt gtccgttaaa gacaaggtca
    18301 catttttcaa gagaaaggct gattcattaa ggcgctctga aatggtattg tacttgaaat
    18361 ctgtcgtaga aaatatagtc gcgtcaggca taaaagtaac tttggtgcct gttttagact
    18421 tgggtgctgt accgattttc ttcaaagtcg tgacaggttt tccaccattt tcgaaacgtt
    18481 gcttgtaaac tgcgccatca cgggtaattt caacttctaa ccagctagaa agggcgttaa
    18541 caacggaaga acccactccg tgaagtccac ctgatgtctt atagccacct tgaccgaatt
    18601 tccctccggc atgaagaatg gtaaagataa cctcaacagt tggaattccc atagcgtgca
    18661 tacctgtcgg catcccacgt ccatggtctt gaaccgttag actaccgtct ttattgatgg
    18721 ttacatcgat acgatcacca aacccagaca aggcttcatc gactgcatta tcaacgattt
    18781 cccaaactag gtgatgaaga ccagcgccat cggtcgatcc aatatacatc cctggacgtt
    18841 ttcggaccgc atccaaccct tctagcacct gaatagcatc atcattataa ttgttaatat
    18901 tgatttcctt ttttgacaca aggaacctcc tattcgttca tctttactat tctacaggtt
    18961 ttccaaggat tttgcaaaat ttttctttct ccgatgtgac aattttagca gagattctct
    19021 gcttttcttt cccaattcat gatataatag gagtatgatt acaatagttt tattaatcct
    19081 agcctatctg ctgggttcga ttccatctgg tctctggatt ggacaagtat tctttcaaat
    19141 caatctacgc gagcatggtt ctggtaacac tggaacgacc aataccttcc gcattttagg
    19201 taagaaagct ggtatggcaa cctttgtgat tgactttttc aaaggaaccc tagcaacgct
    19261 gcttccgatt atttttcatc tacaaggcgt ttctcctctc atctttggac ttttggctgt
    19321 tatcggccat accttcccta tctttgcagg atttaaaggt ggtaaggctg tcgcaaccag
    19381 tgctggagta attttcggat ttgcgcctat cttctgtctc taccttgcga ttatcttctt
    19441 tggagctctc tatcttggca gtatgatttc actgtctagt gtcacagcat cgatcgcggc
    19501 tgttatcggg gttctgctct ttccactttt tggttttatc ctgagtaact atgactctct
    19561 cttcatcgct attatcttag cacttgctag tttgattatc attcgtcata aggacaatat
    19621 agctcgtatc aaaaataaaa ctgaaaattt ggtcccttgg ggattgaacc taacccatca
    19681 agatcctaaa aaataaaatg ccagttctgt gaactgcccc ccaaaagtta gacaattaat
    19741 ttatccgaag gatttagttc tgtattgcac agggctaagt ccttttagtt ttaccttaat
    19801 tctcttgttg ttgtagtaat caatatagtc tataatggct tgttccaatt gcttaagcga
    19861 ctgaaacgac ttctcataac cgtaaaacat ttccgatttc agaatcccaa agaaggactc
    19921 catcatacca ttgtcttggc tgtttccctt gcgtgacatg gatgcttgaa ttcccttact
    19981 ctctaagaac cgatgataag aatcgtgttg
//
LOCUS       DAVBOD010000036        19723 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 640-05
            SAMEA1012484-rid20186543.denovo.036, whole genome shotgun sequence.
ACCESSION   DAVBOD010000036 DAVBOD010000000
VERSION     DAVBOD010000036.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012484
            Sequence Read Archive: ERR059358
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 19723)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19723)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979948.1
            Genome Coverage       :: 595x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:03:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,266
            CDSs (total)                      :: 2,219
            Genes (coding)                    :: 2,091
            CDSs (with protein)               :: 2,091
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 71 of 128
            Pseudo Genes (incomplete)         :: 50 of 128
            Pseudo Genes (internal stop)      :: 33 of 128
            Pseudo Genes (multiple problems)  :: 22 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19723
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012484-rid20186543.denovo.036"
                     /strain="NIG 640-05"
                     /db_xref="taxon:1313"
     gene            complement(181..1359)
                     /locus_tag="VQ862_001381"
     CDS             complement(181..1359)
                     /locus_tag="VQ862_001381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000175872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family transcriptional regulator"
                     /protein_id="HET3115725.1"
                     /translation="MTLSKKQLQLRAKILETVYTLGPISRIEIATKTGITPATTSSIT
                     NDLIKENILLELGEDEHDTSVGRKKILLDIQAKRFYYIGCELSEKHFTFALGDNLGNI
                     LKEEKEIVTKQLIQEKGNQLINQTLKQFLNNCSDYEIEAIGIALPGRYLDDYKITTNN
                     PLWQHIDLEMIQSHFDKPLFFSNNVNCMAIGKRLFSRQQNDPNFAYFHFARGMHCSYI
                     YDGNIYGKGNLMIGEIGHTVVSSEGEECSCGRKGCLQTFAGESWLIKKSKILYHQSPY
                     SLLPSLVKNADDIDIQVILTAYQLGDTGIITLIHQALLYLSQTILNISMMIDSQKIYL
                     HSPLLTNQHIIQKLYSEMNYKPKLLYNRLPEVIIEPYNDFTAAHSAIALCLYHTILHS
                     "
     gene            1639..2901
                     /locus_tag="VQ862_001382"
     CDS             1639..2901
                     /locus_tag="VQ862_001382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000413340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HET3115726.1"
                     /translation="MEKLLQEKLLPVAARLGNNKALVSIRDGITLTIPLLLIGSLLMV
                     IASFPIPGWEKYLGDIGVADYLWKGVDSSFGLLGLVASFGIAYFMARQYKVDGIPAGI
                     VSLSSFITVTPFIRGEAGAGMPTAFMASKGLFVAMILGLINGYIYQWFINHNIQIKMP
                     DGVPPAVSKSFSAIIPGAVTIVGWLIVYATLDKLSLPNLHEIAQVALGGPLGLLGNNV
                     IGLLILIFLNSSFWSVGLHGGNVVNAVMKPLWLANLDANKVAYQTGETLPNIFTSVFM
                     DNFVFIGGGGATIGLVLALGYLAHKKKASKQLKTLAPITVIPGLFNINEPAMFGVPIV
                     LNILLLVPFILAPMFNLLVAWGAMASGLVPLTYTDSGWTMPPVISGLLATGSISGSLL
                     QIVLIVLDVLLYLPFVIAIEKRFKLLED"
     gene            2904..3800
                     /locus_tag="VQ862_001383"
     CDS             2904..3800
                     /locus_tag="VQ862_001383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="haloacid dehalogenase-like hydrolase"
                     /protein_id="HET3115727.1"
                     /translation="MKRLISANPSEILQMNAEELKQSILASEGRVVLSENVVTRETFV
                     GDITNSEIARAFGADMILLNCVDVFEPKIYALDSSGDDVIHRLHQLVACPIGVNLEPI
                     DPSAKMLEETQEIVAGRVASVETLNRIEELGFDFVCLTGNPGTGVSNREIIKAVQTAK
                     ENFSGLIIAGKMHGAGVNEPVAELSVAEQLLEAGADVILVPAVGTVPAFHDQELREVV
                     DLVHSKGGLVLSAIGTSQETSDTDTIKEIALRNKICGVDIQHIGDAGYGGLATVDNIY
                     ALSKAIRGVRHTVSRLARSVNR"
     gene            3815..4132
                     /locus_tag="VQ862_001384"
     CDS             3815..4132
                     /locus_tag="VQ862_001384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001151647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HET3115728.1"
                     /translation="MAKVTIMLACAAGMSTSLLVTKMQKAAEDKGLDAEIFAVPAPEA
                     EEIVATKEVNVLLLGPQVRYLLGDFQEKLKDRQIPVAVIPMTDYGMMNGSKVLDLAES
                     LLD"
     gene            4149..4465
                     /locus_tag="VQ862_001385"
                     /pseudo
     CDS             4149..4465
                     /locus_tag="VQ862_001385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000344536.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
     gene            4475..5077
                     /locus_tag="VQ862_001386"
     CDS             4475..5077
                     /locus_tag="VQ862_001386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HET3115729.1"
                     /translation="MNTMLDKMQEKLSPIAMKVGNQKFLVALRDSFVGTMPVIMTGSI
                     ALLLNAFLVDLPQQFHLESITKTFQWLVDINNLVFKGSIPIVSLLFIYCLGVNIAKIY
                     KVDTVSAGLVSLASFVISIGSTVTKSFPLANVGDVKLDQILQGIDNLAFDGKNLMVTI
                     GNVIPGNHINARGRKGGISSSCWGSVVVTSSERLLETSLR"
     gene            4983..5609
                     /locus_tag="VQ862_001387"
                     /pseudo
     CDS             4983..5609
                     /locus_tag="VQ862_001387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000782422.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="SUMF1/EgtB/PvdO family nonheme iron enzyme"
     gene            5624..6394
                     /locus_tag="VQ862_001388"
     CDS             5624..6394
                     /locus_tag="VQ862_001388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="HET3115730.1"
                     /translation="MVEIIYFLIIIIASGLGSISGMGGGIIIKPLMDSFGYHSVSDIA
                     FYSSFSVFIMAIISTIKRFSQSKEIKWRLIFTVSFSSVLGGFLGHLIFQVLLSQLSVR
                     LVSIVQMILLFVMLLVSFVLTDFKKTYQFDKIGFYMICGLLLGLISSFLGIGGGPLNV
                     SLLMVFFSISIKEATMYSLAIIFFSQLSHLATIVVVTGLNQYHLAPVPVIFLASICGG
                     VLGTVVSKVLPENWVRYCFKGMLFFVMGMTLYNLFHIL"
     gene            complement(6672..6959)
                     /locus_tag="VQ862_001389"
     CDS             complement(6672..6959)
                     /locus_tag="VQ862_001389"
                     /inference="COORDINATES: protein motif:HMM:NF033563.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HET3115731.1"
                     /translation="MIVSLKTKSRKAKDMAESIQGWLAQFLVNLFKSITFDCGKEFSK
                     WKDISNHHDSESFFANLGCSRQRCLNEHSNRLLRCHDLPKQTDFNEVSQEF"
     gene            7163..7435
                     /locus_tag="VQ862_001390"
                     /pseudo
     CDS             7163..7435
                     /locus_tag="VQ862_001390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000547411.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(7545..7748)
                     /locus_tag="VQ862_001391"
     CDS             complement(7545..7748)
                     /locus_tag="VQ862_001391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HET3115732.1"
                     /translation="MSVEEKLNQAKGSIKEGVGKAIGDEKMEKEGAAEKVVSKVKEVA
                     EDAKDAVEGAVEGVKNMLSGDDK"
     gene            complement(7779..8387)
                     /locus_tag="VQ862_001392"
     CDS             complement(7779..8387)
                     /locus_tag="VQ862_001392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000064115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HET3115733.1"
                     /translation="MSNEKNTNTNVEKKDATVVAHEIKGELTYEDKVIQKIIGLSLEN
                     VSGLLGIDGGFFSNLKEKIVNSDDVTSGVNVEVGKTQVAVDLNVIVEYQKNVPALYSE
                     IREIVSSEVAKMTDLEIVEINVNVVDIKTKEQHEADSVSLQDRVSDVAESTGEFTSEQ
                     FEKAKSGLGSGFSTVQEKVSEGVEAVKGAANGVVSHENTRVN"
     gene            complement(8426..8596)
                     /locus_tag="VQ862_001393"
     CDS             complement(8426..8596)
                     /locus_tag="VQ862_001393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HET3115734.1"
                     /translation="MEWLKQYRYPIIAGLIGVFLACLIVSFGFFKTIFVLILGALGVA
                     AGLYIEKNYIDK"
     gene            complement(8608..9174)
                     /gene="amaP"
                     /locus_tag="VQ862_001394"
     CDS             complement(8608..9174)
                     /gene="amaP"
                     /locus_tag="VQ862_001394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000030212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HET3115735.1"
                     /translation="MSKAKKICFIIFCILILTIFLPVLIDYHQVSDLGIHLLSWRQNS
                     VVEFYLARYVFWGTVVLSTLVLLSILVVMFYPKRYLEIQLETKNDTLKLKNSAIEGFV
                     RSLVSDHRLIKNPTVHVNLRKNKCFVHVEGKILPSDNIADRCQIIQNEITNGLKQFFG
                     IERQVKLEVAVKNYQPKPQNKKTVSRVK"
     gene            complement(9258..9422)
                     /locus_tag="VQ862_001395"
     CDS             complement(9258..9422)
                     /locus_tag="VQ862_001395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HET3115736.1"
                     /translation="MGIIANVFAGLVGAYAGQSLLGSWGPSIAGMALLPSIIGAAIVI
                     TVVSFFTGRK"
     gene            9865..11346
                     /locus_tag="VQ862_001396"
     CDS             9865..11346
                     /locus_tag="VQ862_001396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001205273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HET3115737.1"
                     /translation="MRDLLSKKSHRQLELLELLFEHKRWFHRSELAELLNCTERAVKD
                     DLSHVKSAFPDLIFHSSTNGIRIINTDDSDIEMVYHHFFKHSTHFSILEFIFFNEGCQ
                     AESICKEFYISSSSLYRIISQINKVIKRQFQFEVSLTPVQIIGNERDIRYFFAQYFSE
                     KYYFLEWPFENFSSEPLSQLLELVYKETSFPMNLSTHRMLKLLLVTNLYRIKFGHFME
                     VDKDSFNDQSLDFLMQAEGIEGVAQSFESEYNISLDEEVVCQLFVSYFQKMFFIDESL
                     FMKCVKKDSYVEKSYHLLSDFIDQISVKYQIEMENKDNLIWHLHNTAHLYRQELFTEF
                     ILFDQKGNTIRNFQNIFPKFVSDIKKELSHYLETLEVCSSSMMVNHLSYTFITHTKHL
                     VINLLQNQPKLKVLVMSNFDQYHAKFVAETLSYYCSNNFELEVWTELELSKESLEDSP
                     YDIIISNFIIPPIENKRLIYSNNINTVSLIYLLNAMMFIRLDE"
     gene            11708..12703
                     /locus_tag="VQ862_001397"
     CDS             11708..12703
                     /locus_tag="VQ862_001397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000230211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HET3115738.1"
                     /translation="MVEQRKSITMKDVALEAGVSVGTVSRVINKEKGIKEVTLRKVQR
                     AIKTLDYIPDNYARGMKKNRTETIALIIPSIWHPFFSEFAYHVEKELLKYNYKLFICN
                     ADSDSQNEIEYIEMLKQNKVDGIIGITYSDIDKYILSDLPFVSIDRHFSENVCYVTSA
                     NYKGGQTAAEELVRRDNKHLAFIGSINMYENETILRSKGFREKAKELGVDVYNFEMKE
                     PLINPEDQIRIFLQSHKEIDGIFTINDMMALRVISVMKELGKIAPDDYQIIGFDGLKT
                     SVDQSYLVSTIVQDIGMMAKESVAMILKMIKREEILEKRIVIPTYFWGDKTTKKI"
     gene            12830..14140
                     /locus_tag="VQ862_001398"
     CDS             12830..14140
                     /locus_tag="VQ862_001398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HET3115739.1"
                     /translation="MRKGTMLSVVAGLSLAILAGCSGGTNSKQASSSNDIKVWVQFSD
                     ETNEGKAWQKVVDNFNQSGKSKYKVVTEYIPRSGSGGGYEDKVNAAITTNSLPDVITL
                     DGPNTAAYAKSKVITPLDDYLKDNNMDDVLDSIKQQGTYNGKFYAFGFSESNVGVYYN
                     KKMFKEAGIAESELPTLEKPWTWDEFNTIAKKLKDHYNKPAIDFRINSNDEMLPYAYM
                     PLIWSNNGSVVNEDGTKAEGYFNSKESVEAVQFIQNLVKEGYTTVSPVEKGFETGEYP
                     MLLSGSWTIADMNTNYKDIDFGILPYPVSSKTKKLVSPSGSWQLAVTTKSDKKEAASE
                     FVKFATNTESSEIISLGNSVLPIRKSTIENIKDKVSEPMRFLMEQNSKTAHARPVVVA
                     YPQVSRAFQQAMQDISYYEENPNVQKVLDTRTKEMQTAIDQSLK"
     gene            14236..15138
                     /locus_tag="VQ862_001399"
     CDS             14236..15138
                     /locus_tag="VQ862_001399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HET3115740.1"
                     /translation="MSKETVVDTKRREKIKDNILGYSFLAPALILLGIFLVIPVGMVI
                     YYAFTDYYLLTPDERKFVGLENFIRLTKDPIFLKSFLNTLKFVVWIIPVQLGAALGMA
                     LIVNKKRKGNMFFKVAFFAPVVMSLVVISILWLYLLNPNSGLLNAILNKVGIASQPFL
                     TSPKQAMYAIVFVSAWQGAGYQMLLFLGGMQNIPQDVYEAAELDGFSKWAQFRYITMP
                     LLKPTALFVLLTTLISAFKLIVQPMVMTQGGPLNSTITMVYYIYQQGFTDRLVGYSSS
                     IALVFTTLIGMINLVQRRVLKEDD"
     gene            15140..15985
                     /locus_tag="VQ862_001400"
     CDS             15140..15985
                     /locus_tag="VQ862_001400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000819520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HET3115741.1"
                     /translation="MKRFKPTTILEYILLTLLAGLFLFPMVWMVVSAMKPEADVYKNL
                     TSWQAFLPSLNPADWFKPYQEVFERFSIFTYLGNSIFYAGTFAIGSIIVNALAGFAFA
                     KVNFSGKKILFGFLLALLIIPVETVLIPQFTIINSLGLVNNRLAVIIPGLASVFNIYL
                     FRNFFIAIPEEILESAKMDGASIVRIFFRIMLPMSKPAVATVGVLSFISSWNDYIWPL
                     MFLTDSSKFSMQVAITTINTTQPVYINQVMAVLTISTIPLILVYVVAQKYIVQGLGGS
                     GTGIK"
     gene            15995..17314
                     /locus_tag="VQ862_001401"
     CDS             15995..17314
                     /locus_tag="VQ862_001401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 32 protein"
                     /protein_id="HET3115742.1"
                     /translation="MINKTFTVEKANRFIAENKHLVNTQYKPEEHFSAEIGWINDPNG
                     FVYFRGEYHLFYQFYPYDSVWGPMHWGHAKSKDLVTWEHLPVALAPDQDYDRNGCFSG
                     SAIVKDDRLWLMYTGHIEEKTGVRQVQNMAFSDDGIHFEKISQNPVATGSDLPDELIA
                     ADFRDPKLFEKDGRYYSVVAAKHKNNVGCIVLLGSDNLVEWQFESIFLKGVEHQGFMW
                     ECPDYFELDGKDCLIMSPMRYQREGDSYHNINSSLLFTGKVDWGEKCFIPESVQEIDH
                     GQDFYAPQTLLDDQNRRILIAWMQTWGRTLPTHDQEHKWACAMTLPRILRLEDGKLRQ
                     FPVKKGQYQIQIDKDCHYHLGNDTDYLEFGYDSNVQQVYIDRSHLIQKILGEEEQDTS
                     RRYVDIEAKELEVVLDKNSIEIFVNQGEASLTATYYLTVPAELSRID"
     gene            complement(17524..17596)
                     /locus_tag="VQ862_001402"
     tRNA            complement(17524..17596)
                     /locus_tag="VQ862_001402"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(17561..17563),aa:Lys,seq:ctt)
     gene            complement(17861..19132)
                     /locus_tag="VQ862_001403"
     CDS             complement(17861..19132)
                     /locus_tag="VQ862_001403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001113185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication-associated recombination protein A"
                     /protein_id="HET3115743.1"
                     /translation="MPDNLALRMRPKTIDQVIGQEHLVGPGKIIRRMVEANRLSSMIL
                     YGPPGIGKTSIASAIAGTTKYAFRTFNATVDSKKRLQEISEEAKFSGGLVLLLDEIHR
                     LDKTKQDFLLPLLESGLVIMIGATTENPFFSVTPAIRSRVQIFELEPLSNQDVKEALQ
                     IALSNPERGFDFPIELDEDALDFIATSTNGDLRSAFNSLDLAVLSTPENDEGIRHITL
                     DIMENSLQRSYITMDKDGDGHYDVLSALQKSIRGSDVDASLHYTARLIEAGDLPSLAR
                     RLTVIAYEDIGLANPEAQIHTVTALDAAQRIGFPEARILIANVVIDLALSPKSNSAYV
                     AMDKALADLKTSGHLPIPRHLRDGHYSGSKELGNAQDYLYPHNYPGNWVKQDYLPEKI
                     RNHHYFQAEDTGKYERALAQRKEAIDHLRKI"
     gene            19402..19641
                     /locus_tag="VQ862_001404"
     CDS             19402..19641
                     /locus_tag="VQ862_001404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000818079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3115744.1"
                     /translation="MKREVISNGNDGPSQEILIFTKQIRHWILSDQVISGKRKLFFRE
                     DTPKEILDLYENIKSKLDFAYQEVHSNNGLKKYEK"
BASE COUNT         6215 a         3054 c         3851 g         6603 t
ORIGIN      
        1 gatcgattcg tcctgttatt atttcatttc actatacatt atgaaaaagg ggagatagga
       61 gtataattcc aaatataaag aaagcgaaca aaacagaatt ctgattttca gaaaacaggt
      121 ttattcgctt tttatgatat actccctctt tttagcctat ttattaaatg taatagaaaa
      181 ttaagaatgt agaattgtat gatacaaaca aagtgcaata gctgagtgtg cggctgtaaa
      241 atcattgtaa ggttcaataa tgacttcagg taggcgatta tagagcagtt tgggtttgta
      301 gttcatttca ctatatagtt tttggatgat gtgttgattt gttagtaaag gactatgtag
      361 gtagattttt tgagagtcaa tcatcatact gatatttaaa atggtttgac taagatagag
      421 taaggcttga tggataagtg tgattattcc agtgtcacct aattgataag cggttaaaat
      481 aacttggata tcaatatcat cggcattttt gactaaacta ggaagtagag aatagggaga
      541 ttgatgatat agaatttttg attttttgat taaccaagat tctccagcaa aagtttgtaa
      601 gcatcccttg cgcccgcagc tacattcttc tccctcagat gaaacaactg tatgccctat
      661 ttctccaatc attagatttc ctttcccata aatgtttccg tcgtagatat aagaacagtg
      721 catacctcta gcaaaatgaa aataagcaaa attagggtca ttctgttggc gactaaatag
      781 gcgtttacct atagccatac agttaacatt gttagagaaa aacaaaggct tatcaaagtg
      841 ggattgaatc atttctaagt cgatatgttg ccataaagga ttgtttgttg ttattttata
      901 atcatctaaa tagcgaccag gtagcgcgat tccaattgct tctatttcat aatcagagca
      961 gttatttaag aattgcttta gtgtctggtt aatgagttga tttccctttt cttggattaa
     1021 ctgtttagta acaatttctt tctcttcctt taagatattt cctagattat ctcctaaagc
     1081 aaaagtgaaa tgtttttcag atagttcaca accaatgtag taaaatcgtt tagcttgaat
     1141 gtctagcagg attttttttc tccctacgct tgtatcgtgt tcgtcttcac caagttctaa
     1201 gagaatattt tctttaatca gatcatttgt gatactgcta gttgttgcag gtgttattcc
     1261 tgttttagta gcgatttcaa ttcgtgaaat gggacctaat gtgtaaactg tttccagtat
     1321 tttagctctt agttgtaatt gtttcttaga taaggtcata ttagttttct tcctagttgt
     1381 cagattctta aaatcctatg attttttgct atggataaat gtagatgtta atctttttaa
     1441 gcttttcatt acttactggt ctctttttat tatatattga taataaaaaa taatcaaatg
     1501 tttacacaaa tccttgacaa ggctttctta tagttgtaaa atataaataa caaaagataa
     1561 tcaaataaca acttgacgtc aaaaaataaa gataattgat aacttttgat aataaaatat
     1621 atttaagagg aaaaggttat ggaaaaatta ttacaagaaa agttacttcc agtagcggct
     1681 agattgggta ataataaagc gttggtttct attcgagacg gtattactct aactatacct
     1741 ttattgttga taggttcatt actaatggtt attgcaagtt ttcctattcc aggatgggaa
     1801 aaatatctgg gtgatattgg tgttgctgac tatttatgga agggtgttga tagtagtttt
     1861 ggattacttg gtcttgtagc tagttttggt atcgcttact ttatggctag acaatacaaa
     1921 gttgatggta ttcctgctgg tattgtgtca ttatcatctt ttattacagt tacgcctttc
     1981 attagaggag aggctggagc aggaatgcct accgctttca tggcatcaaa aggtttattt
     2041 gttgctatga ttttaggatt gattaatggc tatatctacc aatggtttat aaatcataat
     2101 atacagataa aaatgccgga tggtgttcca ccagcagtat ctaaaagctt tagtgccatt
     2161 attcctggtg cagtgactat tgttggttgg ttgattgttt atgcaacttt agataaatta
     2221 agtttaccta atcttcatga aattgctcaa gtagctttgg gaggtccact tggactttta
     2281 ggaaataatg ttattggtct tcttatctta attttcctta atagtagttt ttggtctgta
     2341 ggattacacg gaggaaatgt tgttaatgca gttatgaaac cgttatggtt agctaatcta
     2401 gatgcaaata aagtagctta tcaaactgga gaaactcttc caaatatttt tactagcgta
     2461 tttatggata attttgtatt cataggtggc ggtggtgcaa ccataggttt agttcttgcg
     2521 ttaggatatt tagcacataa gaagaaagct agtaaacaac taaaaacttt ggcacctata
     2581 actgttatac ctggattatt taatataaat gaaccagcaa tgtttggcgt tcctattgtt
     2641 ttgaacattt tgttactagt tccatttatc ttagctccaa tgtttaactt actagtagcg
     2701 tggggagcaa tggcatcagg tttggttccg ctaacttata cagattcagg ttggactatg
     2761 ccacctgtta taagtggttt acttgctaca ggaagtattt ctggttcatt attacaaatt
     2821 gtattgattg ttttggatgt cttactttat ttaccatttg taatagctat tgaaaaacgg
     2881 tttaagttat tggaggattg agaatgaaac gtttaattag tgcaaatcca tctgagatat
     2941 tacagatgaa tgctgaagaa ttaaaacaaa gtattttagc aagtgaaggt agagttgttc
     3001 tatctgaaaa tgtagttact cgtgagacat ttgttgggga tataactaat tctgaaattg
     3061 ctagagcttt tggagctgat atgattttat tgaattgtgt tgatgttttt gagcctaaaa
     3121 tttatgcttt ggatagttca ggtgatgatg ttattcatcg cttacaccag cttgttgctt
     3181 gtccaattgg tgtaaatttg gaaccgattg acccatctgc aaagatgcta gaggaaacac
     3241 aggaaattgt tgcaggtcgt gttgctagtg ttgaaacatt gaatcgaata gaggagttag
     3301 gttttgactt tgtctgtttg actggaaatc ctggaacagg agttagcaat cgagaaatca
     3361 ttaaggctgt tcaaactgct aaggaaaact tttctggttt gattattgca ggtaagatgc
     3421 acggggcagg agtgaatgag cctgtggcag agctttctgt cgcagagcaa ttgttggaag
     3481 caggtgcgga tgtgatactt gttccagcag ttggaaccgt tccagccttt catgaccaag
     3541 agttgcgtga agtcgttgat ctcgttcata gtaagggtgg tcttgtattg agtgctattg
     3601 gtactagcca agaaacatct gatacagata ctattaagga aattgcactt agaaataaaa
     3661 tttgtggagt tgatattcaa catataggtg acgcaggata tgggggactg gcaacagtcg
     3721 ataatattta tgcattgagc aaggcaatta gaggagtgag acatacagta tctcgcttgg
     3781 ctaggtcagt aaataggtga taaaggagta agctatggct aaagtaacaa ttatgttagc
     3841 atgtgcagca ggtatgagta caagtctgct agtgacaaag atgcaaaagg cagcagaaga
     3901 taaggggttg gatgcagaaa tttttgcagt tccagctcct gaagcagaag aaattgtagc
     3961 aacaaaagaa gtaaatgtgt tgcttttagg cccccaagtt cgctatttac taggggactt
     4021 tcaagaaaaa ctaaaagata gacagattcc tgtggcggtt attccgatga cagattacgg
     4081 aatgatgaat ggttctaaag ttttagattt agctgaaagt ttattagact aagattgagg
     4141 agaatgttat ggatgaaagt aatttagaat ctgtaatggg gctaattatg tatggtggag
     4201 atgccaaaag taatgctatg gaggctattc aggcagcaaa aaaagggatt tctctaaagc
     4261 caatcgaaga ttagctgatg cgaatgctgc cttattacag gcgcataagg ctcaaacaga
     4321 aatgttgaca agagaggcac aggggggaaa aacatcaatt agcctcttga tggtacacgc
     4381 gcaagatcat ttaatgacga gtctgacttt tgttgacttg gcgaaagaag tggtagaagt
     4441 atacgaacga tttgaaaaaa attaggagtt tggtatgaat acaatgttgg ataaaatgca
     4501 agaaaaactt tctccaattg caatgaaagt tgggaatcag aagtttttag ttgctttacg
     4561 tgattcattt gtggggacta tgcctgttat tatgacaggt tccattgctt tgttattaaa
     4621 tgcttttcta gtggatttac cacaacaatt tcacctagaa agtattacga aaacctttca
     4681 gtggcttgtt gacatcaata atttggtatt caagggaagt ataccaattg tttccttgtt
     4741 gttcatctat tgcttgggag tgaatatcgc taagatttac aaggttgata cagtttctgc
     4801 tggtttggta tcacttgctt cgtttgtcat ttcgattgga agtacagtta caaagagttt
     4861 ccctttggca aatgtaggag atgtgaaatt agatcagatc ttacaaggaa ttgataatct
     4921 agcatttgat ggtaaaaatc tgatggtaac tattgggaat gtgattccag gaaaccatat
     4981 taatgccaga ggcagaaagg gagggatatc ctcatcctgc tggggctccg tggtggttac
     5041 aagttccgaa cgcttgctgg aaacatccct acggtgagaa tagtaatcta gtgggtttag
     5101 aagaccatcc agtagttcat gttgctttag aagatgcatt ggctttctgt aattggagcg
     5161 gaatgtcttt accgactgaa gcacagtggg aatatgctgc tagaggagga agacaatctg
     5221 aatatccttg gggagatact cttttagaag gtggatatta tcatgccaat acttggcaag
     5281 gaagatttcc ttatgaaaat actgtctcag atggatttat aggaacggct cctgtctatg
     5341 aatttttacc taatgatttt ggtctatatc aaatgattgg gaatgtttgg gaatggtgtc
     5401 gcaatccgag atatacctta ttagctagtt ttaatgaaga tgactatgag ttgccaaaat
     5461 atgggataca agatgaggag tatgctatca gaggaggttc ctttttatgt cattgttctt
     5521 attgtaatcg ataccgagta gctgctagaa atggatgtat ttctacttcc actagtagcc
     5581 atctaggttt tagatgtttg aaagaatagg atggacttaa aaagtggttg agattattta
     5641 ttttctaatc attataatag ctagtggatt gggttctata tcaggcatgg gtggtggaat
     5701 tataattaag ccacttatgg atagttttgg gtaccattcg gtcagtgata ttgcttttta
     5761 ttctagtttc tctgttttta taatggcgat tatttcaaca atcaaaagat tttcacaaag
     5821 taaagagata aaatggagat tgatttttac ggtatccttt tcttctgttt taggaggatt
     5881 tctaggtcat cttatttttc aagttttgtt atctcaatta tcagtacggc tagtatccat
     5941 tgttcaaatg attttactat ttgtgatgct acttgtatca tttgttttaa cagattttaa
     6001 aaaaacttat caatttgata agataggatt ctatatgatt tgtggtcttc tattgggctt
     6061 aatttctagt tttttaggga ttggtggtgg tccgctcaat gtatctttat tgatggtgtt
     6121 tttttctatt tcgataaaag aagcaacgat gtattctctt gcaattattt tcttttccca
     6181 gctgtctcat ttggctacaa ttgttgtggt tacaggttta aatcagtatc atttagcacc
     6241 tgttccagtt atttttcttg cttctatatg cggaggggta ttggggacgg ttgtatcaaa
     6301 agtcttacct gaaaattggg taagatactg ttttaaaggg atgttattct ttgtcatggg
     6361 aatgacttta tataatttat ttcatatttt gtaaggtcag tgtgaaaata tttaaataga
     6421 cttcctgtaa aaactggatt taacgccctc catttgtcaa attaagctag acagtcttac
     6481 caactcagaa aatatctgat gaggtatttg gtatccaaag gatttaggtg ggatgtgatt
     6541 tcttgaggct gggaaaaagt ctttaaaatt aaaaaatgca taatatcagg tgttggaaaa
     6601 actttgatac tatgcgtttt attgtgggaa tatttatttc attttctcct gaaattgagt
     6661 ttttgtccag cctaaaattc ttgactgact tcgttgaaat ctgtctgctt tggcaagtca
     6721 tgacacctta aaagtctatt tgaatgttcg ttgagacacc gctgtcttga acatcctaga
     6781 ttcgcaaaaa agctctcact atcgtgatga ttggaaatat ctttccattt tgaaaactct
     6841 tttccacagt caaacgtaat agatttaaag aggttcacta gaaattgtgc cagccaccct
     6901 tggatggatt ctgccatatc ctttgcctta cgactcttgg tcttcaaact gacaatcaat
     6961 tgactatacc tgttcgctca caaataggag agaactgttt acgaaaatct aatgaatatg
     7021 ccacaagaac attataccgc aacgtgtact atttttggtt cattttacta tagaaactat
     7081 tgaagaacct gtacgaaaat atatcatgaa aaagggtaga tagaaagcaa acagccttga
     7141 aatcaatgtt gactgcgatt atgaacctga atcagcccct caaaagggac tgtatatgaa
     7201 tgaacgttac cagtgtttaa aaactaaaga atatcaggca cttttatctt ccaagggtag
     7261 acaaattttc gctaaacgta agattgatat gaaatctgtc tttgggcaga taaaggtttg
     7321 tttgggttat aagagatgtc atctgagagg gaagcgtcaa gtgagaattg acatgggatt
     7381 cgtactcatg gccaacaacc tgctgaaata taataagaga aagaggcaaa attaaaaagc
     7441 tagagttccg caattgggaa tccctagctt tttgttttct gagaatcatc ttgactcaga
     7501 ctcttttgac taatgttact aaaaagataa agtaactttt aaccttattt atcgtcgcca
     7561 ctcaacatgt ttttaacacc ttctacagca ccttctacag cgtctttggc atcttcggcg
     7621 acttctttta ctttagaaac aactttttca gctgctcctt ctttttccat tttttcatca
     7681 ccgatggctt tcccaacacc ttctttaata gaacctttag cttgatttaa tttttcttct
     7741 actgacatga taatttctcc tgttatattt attttatctt agtttacacg agtgttttcg
     7801 tgagatacta caccatttgc tgcaccttta acagcttcta caccttcgct aactttttct
     7861 tgaacagttg agaaaccaga tccaagacca gatttagctt tttcgaattg ttctgaagtg
     7921 aattctcctg ttgattcagc aacgtcagat acgcgatctt gaaggcttac tgagtctgct
     7981 tcatgctgtt ctttagtttt gatgtcgaca acgtttacgt tgatttcaac aatttccaag
     8041 tcagtcattt tagcaacttc tgaagatacg atttctctga tttctgaata taaagctgga
     8101 acattttttt ggtactcaac aataacgttt aagtcaactg caacttgtgt tttaccaact
     8161 tctacgttaa caccacttgt tacgtcatcg ctgttaacga ttttttcttt aagatttgag
     8221 aagaaaccac catcgattcc caaaagacct gaaacgtttt ctagtgaaag accaatgatt
     8281 ttttggataa ctttatcttc gtaagtaagt tcccctttga tttcgtgagc tacaacagta
     8341 gcatctttct tttctacgtt agtgtttgtg tttttttcgt ttgacatatg aaactccttt
     8401 aattaaatta gtaattttta tttttttatt tatctatata gtttttttcg atatataatc
     8461 cagctgcaac tcccagtgct cctaaaatca atacaaatat tgttttgaag aagccaaagg
     8521 agacaatcaa acaagccaga aatacgccta tgagaccagc gataattgga tatcgatatt
     8581 gtttaagcca ttccattttt tacttcctta cttcacacga ctaacagtct ttttgttttg
     8641 aggttttggt tggtaatttt ttactgcaac ttcaagtttt acttgacgct caataccaaa
     8701 aaactgcttc aatccattag ttatttcatt ttgaattatt tggcatctgt cagcgatgtt
     8761 gtctgaagga agaattttac cttctacatg aacgaaacat ttattttttc gtaaatttac
     8821 atgaacagtt gggttcttga tcaatctatg atcactcacc aaacttctaa caaaaccttc
     8881 gattgccgaa ttctttaatt ttaatgtatc gtttttagtt tcaagttgga tttccaagta
     8941 acgtttagga taaaacatca caactaaaat ggataataaa actaaagttg atagaaccac
     9001 tgtcccccaa aagacatatc tagcaagata gaattcaact acggagttct gtctccagct
     9061 aagtagatga atacctagat cactaacttg atgataatct atcaaaacag gaaggaaaat
     9121 tgtcaagatt aaaatacaga aaataatgaa acatattttc tttgcttttg acatatacaa
     9181 tcctttcgat ttaacattta aactattttt cccgtcattg atttaaaaat agtttgctaa
     9241 ctttactggc gaaaagttta ctttctacct gtaaagaatg acactacagt aatcacaatc
     9301 gctgcaccta taatagatgg gagcaaagcc attccagcga ttgatggacc ccaactacct
     9361 aaaagagatt gtcctgcata tgccccgact aaaccagcga atacatttgc gatgattccc
     9421 atagaactac ttttttagtg attttacctg ccaagagacc aataagacct ccagcaataa
     9481 ttgatcacaa cactgcctac cctccttttt tattttaata tcaaaaaatc aatttctttg
     9541 attaatacta ttatataact ttaatataga aaagtcaatt atttcgattg ttattattat
     9601 ataattttaa aaaatcaaat tctttaattg ttgctattat ataattttta aaattaaaaa
     9661 tataatcttt agacttgaat ttgattctgt attcacgccc tcaatagacg gtaaaataag
     9721 aaaattgttt atatattgtc tccgtagtgt tattatacga aataaaagat tttaggaaaa
     9781 gtcgttatat catgctatac ctattctttg tggtataatt gcaagaggtt taatccgata
     9841 atttataaag agagaaagat attcatgaga gatttattat ctaaaaaaag tcataggcaa
     9901 ttagaattat tagaattatt atttgaacat aaacgttggt ttcatcgttc tgaactagca
     9961 gagttattaa attgtacaga acgtgcagtc aaagatgatc tatcccatgt taaatctgct
    10021 tttcctgact tgatttttca ttcttctact aatggtatac gcattattaa taccgatgat
    10081 agtgatattg aaatggttta ccatcatttc tttaaacatt caactcattt ttcgatttta
    10141 gaattcatct tctttaatga aggttgtcaa gctgagagta tttgtaaaga attttatatc
    10201 agttcatctt cgctctatcg tattattagc caaatcaata aagtgattaa aaggcaattt
    10261 caatttgaag tcagtctgac ccctgttcaa atcattggaa atgagagaga cattcgttac
    10321 ttttttgcac aatatttttc agaaaaatat tatttcctag aatggccatt tgaaaatttt
    10381 tcatcagagc cactatctca attgttagaa ttggtttata aggaaacaag ctttccaatg
    10441 aatttgtcaa cgcatagaat gctaaagttg ctcctagtta cgaacctata tagaataaag
    10501 tttggtcatt ttatggaagt agataaagat tcttttaacg accaaagttt ggatttttta
    10561 atgcaggcag aaggaataga aggtgttgct cagagttttg aatcagaata caatatctct
    10621 ttagatgaag aagttgtttg ccaattattt gtgtcttact ttcaaaaaat gtttttcata
    10681 gatgaaagtc tctttatgaa atgcgtaaaa aaggatagtt atgttgaaaa atcttaccat
    10741 ctattgagtg attttattga tcagatttca gtcaagtatc agattgaaat ggagaataag
    10801 gataatctga tttggcatct gcataatacc gcacatctgt atcgtcaaga gttgtttact
    10861 gagtttattt tatttgatca aaaagggaat acaatcagga actttcaaaa tatttttcca
    10921 aaatttgttt cagatataaa aaaagagctt tctcactatt tagagactct tgaggtttgt
    10981 tctagttcaa tgatggtaaa tcatctatct tataccttca tcactcatac caaacatttg
    11041 gtgattaatt tgctacaaaa tcagcctaaa ctaaaggttt tagttatgag taattttgat
    11101 cagtatcatg caaaattcgt tgcagagaca ctttcttatt actgtagcaa taattttgaa
    11161 ctggaagttt ggactgaatt agaattatca aaggaatctt tagaagattc accttatgat
    11221 atcattattt ctaattttat tattcctcct attgaaaata agagactcat ctattcaaat
    11281 aatataaaca cggtctcact catatacttg ttaaatgcca tgatgtttat tcgattagat
    11341 gagtaaccaa aaataacaaa aaaacgctat ttcgcgtttg aactgtacct caaaagttag
    11401 acagaaaaaa tctaattttt ggggtgtttt tgttaagaaa agaccttcaa tcatttaagc
    11461 aaaatgtaca tctagattta tagccctcta aaactcttgc tttttttgta gaagatacga
    11521 aaaaagccat aaaaccaagg cttttcctgt tttatgtaga tgtttacaca tgaaaattga
    11581 agtattttca aaagctaatt ggagtgattt tattcatgat gggataaatg atctggccaa
    11641 aaatgattga gaaatagttg cttaaaaagc atttgcatga tactatatat tgaaaggagg
    11701 tgataatatg gtagaacaaa gaaaatcaat taccatgaaa gatgttgctt tagaagcagg
    11761 agttagtgtt ggaactgttt cacgtgtaat taataaagaa aaaggcatta aagaagtaac
    11821 tttaaggaaa gttcaaaggg ctataaaaac attggactat atccctgata attatgctcg
    11881 aggtatgaaa aagaatagaa cagaaactat cgctttgatt attccgagca tatggcatcc
    11941 atttttttcg gagtttgcct atcatgttga gaaagagtta ttaaaatata attataaatt
    12001 atttatttgt aacgctgata gcgattcaca aaatgaaatc gaatatatcg aaatgttgaa
    12061 acaaaataaa gtggatggaa ttattggtat tacatattct gatattgaca aatatatttt
    12121 atctgattta ccgtttgtaa gtatagatag acatttttcg gaaaatgtat gctatgttac
    12181 ttcagcaaat tacaaaggag gacaaactgc agcagaggaa ctggttagaa gggataataa
    12241 gcaccttgct tttattggtt caattaatat gtatgagaat gagactatac tcagaagtaa
    12301 aggattcaga gaaaaagcta aggaattagg agtagatgtc tataattttg aaatgaaaga
    12361 acctttaata aatcctgaag atcagataag aatttttttg caatctcata aagaaattga
    12421 tggtatattt acaataaatg atatgatggc tctgagagtt attagtgtta tgaaagaact
    12481 ggggaaaata gcacctgatg attaccagat aattgggttt gatggtttaa aaacttctgt
    12541 cgatcaatct tatctagtgt ctacaatagt tcaagatatt ggtatgatgg caaaagaatc
    12601 tgttgcaatg atactgaaaa tgattaagcg agaagagatt ctagaaaaac gaatcgtaat
    12661 tcccacatat ttttggggag ataaaacaac aaaaaaaatt taaaaagcgc ttgacaatta
    12721 atgaaagcgc tgttataata taatcaacaa atgaaacgtt tcaaaaatag gctagaagct
    12781 tgtttaaaaa ataaataaaa aatgaaacgt ttcaaaaagg aggaaaatga tgcgtaaagg
    12841 tacaatgtta tctgttgttg cggggctatc gttagctata cttgcaggtt gtagtggagg
    12901 aactaactca aaacaagcga gttcttcaaa tgatattaaa gtctgggtac aattctctga
    12961 cgaaacaaat gaaggaaaag cttggcaaaa agttgttgat aactttaatc aatcaggaaa
    13021 aagtaagtac aaggttgtaa ctgagtatat tcctcgtagt ggtagtggtg gaggatatga
    13081 agacaaggtt aatgctgcta ttacgactaa tagtcttcca gatgttatta cccttgatgg
    13141 accaaatacg gcagcttatg caaaatctaa agtaattact ccgctagatg attatctaaa
    13201 agataataat atggatgatg ttttggacag tattaaacaa cagggaactt ataatgggaa
    13261 attctatgca tttggatttt ctgaatcgaa tgttggtgtt tattacaata aaaaaatgtt
    13321 caaagaggcc ggaattgcgg aatcagagct tccaacgcta gaaaagccat ggacatggga
    13381 cgaatttaat acgattgcta aaaaattgaa agatcattat aacaaaccag caattgattt
    13441 tcgtattaat tcaaacgatg aaatgttgcc atatgcttat atgccgttga tttggtcaaa
    13501 taatggttct gtcgtaaacg aagatggaac aaaggcagaa ggatacttca actccaaaga
    13561 gagtgtagaa gcagttcaat tcattcaaaa tcttgtaaaa gaaggctata caactgttag
    13621 tccagtcgaa aaaggttttg aaacaggaga gtatccaatg cttttgagtg gttcttggac
    13681 gattgctgac atgaatacaa actacaaaga tattgatttt ggtatccttc cttacccagt
    13741 atctagtaag acgaaaaaat tagtatcccc ttcaggtagt tggcaattag ctgtgacgac
    13801 aaaatctgat aaaaaagagg ccgcatctga atttgttaaa tttgctacaa atacagaatc
    13861 aagtgaaatt attagcttgg ggaattcggt ccttccaatt cgtaaatcta caattgaaaa
    13921 tatcaaagat aaagtatccg aaccaatgcg tttcttgatg gaacaaaatt caaaaacagc
    13981 tcatgctcgc ccagttgttg tagcatatcc tcaggtttct cgagcttttc aacaagcaat
    14041 gcaagatatt agctattatg aagaaaatcc aaatgtgcaa aaagtcttgg atactcgtac
    14101 aaaagaaatg caaactgcta ttgatcagtc actcaaataa tctgtaaaaa agaaggtgga
    14161 aggaaaatgt ttggaactac cttccccttt cttgttaata gcctagtttg atatatatga
    14221 ttaaaggaga tggatatgag taaagaaact gttgtggata caaaaagacg tgaaaaaata
    14281 aaggataaca tattaggtta tagtttttta gctccagctt taattttatt aggtatcttt
    14341 ttagtaattc cagttggaat ggtcatttat tacgctttta cagattatta tttgttgaca
    14401 ccagatgaaa gaaaatttgt tggacttgaa aattttattc gattaacaaa agatccgatt
    14461 ttcttaaaga gcttcttgaa tactttgaaa tttgttgttt ggattattcc agttcaattg
    14521 ggagcggcct taggaatggc tttgattgtc aataaaaagc gaaaaggaaa tatgtttttt
    14581 aaagtggctt tttttgctcc agttgtcatg tccttggtag ttatttctat tctttggctt
    14641 tatcttttaa atccaaatag tggcttattg aatgctattt taaataaggt aggtattgct
    14701 tctcaacctt tcttgactag tcctaaacaa gctatgtatg caattgtttt tgtttctgct
    14761 tggcagggtg caggttatca gatgctttta tttttaggag gaatgcagaa tattccacaa
    14821 gatgtctatg aagctgctga attagatgga ttctcaaaat gggctcagtt tcgttatatc
    14881 acgatgcccc tactaaaacc aacagccctg tttgtattgt taacaacttt aatttctgct
    14941 tttaagctga ttgtacaacc aatggttatg acgcaaggtg ggccattaaa ctcaacaatt
    15001 actatggtgt actatattta tcaacaaggt tttactgatc gtcttgtagg atattctagc
    15061 tcaatcgctt tagtatttac aacgttaatt ggtatgatta acttagtaca acgtcgcgtt
    15121 ctgaaggagg atgactaaga tgaaacgatt taaaccaaca acaatcttag aatatattct
    15181 gttaacttta ttggcaggac tcttcctttt tcctatggtt tggatggtag tttcagctat
    15241 gaagccagaa gcggatgttt ataaaaattt gactagttgg caagccttct taccaagttt
    15301 aaatcccgct gattggttta aaccttatca ggaagtattt gagcgcttta gtatttttac
    15361 atatctaggg aacagcattt tttatgctgg aacgtttgct attggttcta ttattgtcaa
    15421 tgcactggcc ggtttcgctt ttgcaaaagt caatttttca ggtaagaaaa ttttatttgg
    15481 tttcttactt gctttactta ttattccagt ggaaactgtg ttaattccac aatttaccat
    15541 tatcaattcc ttaggtttgg tcaataatcg tcttgcagtt attattccag gattggcgag
    15601 tgtatttaat atttacttat ttaggaattt ctttattgca attccagaag agattcttga
    15661 gtctgcaaag atggacggag caagtatcgt tagaattttc tttagaatta tgcttccaat
    15721 gtctaaacct gcagttgcta cagttggtgt tttatcattt atttcaagct ggaatgatta
    15781 tatctggcca ttgatgtttt tgacagattc ttctaaattt tcaatgcagg ttgcaattac
    15841 aactattaat acaactcaac cagtttatat caatcaggta atggctgtat taactatttc
    15901 aacgattccg ttgattttgg tctatgtagt cgctcagaaa tatattgttc aaggtctggg
    15961 tggttccgga actggaataa aataggatat acttatgata aataaaacat ttacagtaga
    16021 aaaagccaat cgttttatag cagaaaataa acatctcgtt aatactcaat ataagcctga
    16081 agaacatttt tcagctgaga ttggttggat caatgatcca aatggatttg tctattttcg
    16141 tggagaatac catctctttt atcaattcta tccatatgat agtgtttggg ggcctatgca
    16201 ctggggacat gctaaaagta aggacttggt gacttgggag cacttgccag tggcacttgc
    16261 tcctgatcaa gattatgacc gaaatggttg tttctcaggc tctgccattg tcaaggatga
    16321 tcgcctctgg ctcatgtaca ctgggcatat cgaagaaaaa accggtgtcc gccaagtgca
    16381 aaatatggca ttttcagatg acgggattca ctttgaaaag atttcccaaa atccagttgc
    16441 aactggatca gacttgccag atgagttgat tgctgctgat ttccgtgatc caaaactctt
    16501 tgaaaaagat ggacgctatt actccgtagt agctgccaaa cacaagaata atgtgggctg
    16561 tatcgttcta ctagggtccg ataacctagt agaatggcag ttcgaatcca tctttttaaa
    16621 aggggtagaa caccaaggct ttatgtggga atgcccagat tacttcgagt tagatgggaa
    16681 agattgcctt attatgtcac ccatgcgtta tcagcgtgag ggagactcat atcataacat
    16741 caactcatcg cttttgttca cgggtaaggt agattgggga gaaaaatgtt ttatcccaga
    16801 atcagttcaa gaaattgatc atggccaaga cttctatgcg cctcaaacat tgttggacga
    16861 tcaaaatcgt cgtatcctga ttgcttggat gcagacatgg gggcgtaccc ttccaaccca
    16921 tgaccaagaa cacaagtggg catgtgccat gactttacct agaattctaa gattggaaga
    16981 tggcaaacta agacaattcc ctgttaaaaa aggccaatat caaatccaaa tagataaaga
    17041 ttgtcattac cacttaggaa atgatacaga ttatcttgaa tttggttatg acagtaatgt
    17101 gcagcaagtt tacattgatc gtagccatct tattcaaaaa attctaggtg aagaagaaca
    17161 ggacactagt cgacggtatg tagatattga agctaaagaa ttggaagttg ttctagataa
    17221 aaattccatc gagatttttg tcaatcaagg tgaagcaagc ttgactgcaa cttattactt
    17281 aacggtgcca gctgagctat cacgaattga ttaaaaatta agttatttct cctaaagaaa
    17341 aagttctctt tctaaaatag tggaaagagg actttttgtg ttttgggtat ataagcttag
    17401 tttatggtat ttgtaaaatt ggtgttggat tatgatttaa actagttttc taaagaattt
    17461 gaaaaaaatt ttatttaagc aaaaaaagcc ctatattata agacttttcc tgttgtattt
    17521 atatgccccc tacagggatc gaacctgtga cccacggatt aagagtccgc tgctctgcca
    17581 gctgagctaa ggaggcaaag aaaaaagctg tattggtgcc gaaacttcac ggtttgtatt
    17641 gaacccgcgc aattaagcag gtgggcaact cgctctaact gaagctgttt ccgtgtgaga
    17701 cggcctacat gctgttagaa gacttttgtt tccctaataa tacaaaaaat agtcggtcaa
    17761 cacttaagtg tgaagtcgta caccacagcg tttctatatt tatatgatac cactttttta
    17821 aaaaaaatca agaggaaagt gcaatttttt gaaaaggatt tcagattttt cgcaaatggt
    17881 cgatagcttc ctttctttga gccaaagccc gttcatattt accagtatct tctgcttgga
    17941 aatagtgatg attacgaatt ttttctggca gatagtcttg ctttacccaa tttccaggat
    18001 agttgtgtgg atagagatag tcttgggcat tccccagttc cttgcttcca ctgtagtgcc
    18061 catcacgtag gtgtcgcgga ataggcaagt gccctgatgt tttgaggtca gcaagtgcct
    18121 tatccatagc tacataggct gagttggatt ttggagaaag ggccaaatca atcacgacat
    18181 tggcaatgag aatgcgggct tcggggaaac caatcctttg tgcagcatcc agagcagtca
    18241 cggtatgaat ctgggcctca ggattggcta agccgatatc ttcataggcg ataacagtca
    18301 agcgacgagc gagactaggc agatccccag cctcaatcaa gcgggcagta tagtggagac
    18361 tggcatccac atctgagcca cgaatagact tttgcagggc agatagaaca tcatagtgac
    18421 cgtctccatc cttgtccata gtgatgtagc ttctctgaag actattttcc atgatgtcta
    18481 aggtgatgtg gcgaatgccc tcgtcattct caggggtaga tagaacagcc aagtccagtg
    18541 agttaaaggc agagcgaagg tctccgtttg tagaggttgc gatgaaatcc agcgcatcct
    18601 catctagttc tattggaaaa tcaaaaccac gttcagggtt acttagagct atctgcaggg
    18661 cctctttgac gtcttggtta gacagaggtt ccaactcgaa aatttgaaca cggctacgaa
    18721 tggcaggagt gacagagaag aaaggatttt cagtcgttgc tccaatcatg atgaccagtc
    18781 cactttccaa gagaggcaag aggaagtctt gcttggtctt atctagtcga tgaatttcgt
    18841 ctagcaatag gacgagacca ccagaaaatt tagcttcttc cgagatttct tgcagtcgct
    18901 ttttactatc aactgtcgca ttgaaagttc gaaaggcata cttggtcgtt ccagcgatgg
    18961 cagaggcaat actggttttg ccgattcccg gagggccata tagaatcatg gaggacaggc
    19021 ggttggcttc caccatgcgg cggatgattt ttccaggtcc gaccagatgc tcctgaccga
    19081 tgacctggtc gatggtttta gggcgcatgc gaagcgcgag attgtctggc atagcagtcc
    19141 tttctaacgt ggatttgagt agaatgactc atctactata tcttactatg tccattctag
    19201 cctattagtt gtgatatttc aatggttttg taataatcag ggagtgagat agaatctttt
    19261 ttactattta atttaatgag gagaggtatc agcatgagag atttgatttt ccttaaagct
    19321 caaaatagga tagttgagcc taaagaagtg gaagtgctga cttgagaaat aatattgctg
    19381 aatgtcattg tatgaactat aatgaaaaga gaggtgataa gcaatggaaa tgatggacca
    19441 agtcaggaaa ttttgatttt tacaaaacaa attcgtcatt ggattcttag tgatcaagtt
    19501 atttcaggga aaagaaaact tttcttccgg gaagatactc caaaagagat tttagatttg
    19561 tacgaaaaca ttaaatctaa acttgatttt gcttaccaag aagttcattc taataatggg
    19621 ttgaaaaaat atgaaaaata gaataattga tgtttttgaa gtagtaaatc gcctccttgt
    19681 aataactgtt gaaaatcctg atttcgaaga cttgagagtt aat
//
LOCUS       DAVBOD010000037        19123 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 640-05
            SAMEA1012484-rid20186543.denovo.037, whole genome shotgun sequence.
ACCESSION   DAVBOD010000037 DAVBOD010000000
VERSION     DAVBOD010000037.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012484
            Sequence Read Archive: ERR059358
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 19123)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19123)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979948.1
            Genome Coverage       :: 595x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:03:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,266
            CDSs (total)                      :: 2,219
            Genes (coding)                    :: 2,091
            CDSs (with protein)               :: 2,091
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 71 of 128
            Pseudo Genes (incomplete)         :: 50 of 128
            Pseudo Genes (internal stop)      :: 33 of 128
            Pseudo Genes (multiple problems)  :: 22 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19123
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012484-rid20186543.denovo.037"
                     /strain="NIG 640-05"
                     /db_xref="taxon:1313"
     gene            complement(119..751)
                     /locus_tag="VQ862_001405"
     CDS             complement(119..751)
                     /locus_tag="VQ862_001405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000200889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HET3115745.1"
                     /translation="MTSITAIFFDLDGTLVDSSIGIHNAFTYTFKELGVPSPDAKTIR
                     GFMGPPLESSFATCLSKDQISEAMQIYRSYYKAKGIYEAQLFPQIIDLLEELSSSYPL
                     YITTTKNTSTAQDMAKNLEIHHFFDGIYGSSPEAPHKADVIHQALQTHQLAPEQAIII
                     GDTKFDMLGARETGIQKLAVTWGFGEQADLLNYQPDYIAHKPLEVLAYFQ"
     gene            complement(773..1645)
                     /gene="sdaAA"
                     /locus_tag="VQ862_001406"
     CDS             complement(773..1645)
                     /gene="sdaAA"
                     /locus_tag="VQ862_001406"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000500050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent,
                     subunit alpha"
                     /protein_id="HET3115746.1"
                     /translation="MFYSIKELVEQADLDFQGNVAELMITTEFELTGREREEVFLLME
                     RNLEVMKASVQLGLNENKSRSGLTGGDAAKLDHYIKNEKTLSDYTILSAARNAIAVNE
                     HNAKMGLVCATPTAGSAGCLPSVLTAAIEKLDLSHEQQLDFLFAAGAFGLVIANNASI
                     SGAEGGCQAEVGSASAMSAAALTLAAGGTPYQASQAIAFVIKNMLGLICDPVAGLVEV
                     PCVKRNAMGASFAFIAADMALAGIESKIPVDEVIDAMYQVGASMPTAFRETAEGGLAT
                     TPTGRRLQKEIFGE"
     gene            complement(1654..2325)
                     /gene="sdaAB"
                     /locus_tag="VQ862_001407"
     CDS             complement(1654..2325)
                     /gene="sdaAB"
                     /locus_tag="VQ862_001407"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015606087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent
                     subunit beta"
                     /protein_id="HET3115747.1"
                     /translation="MKSLRFQSVFDIIGPVMIGPSSSHTAGAVRIGKIVSSIFDDTPT
                     EVEFQLFNSFAKTYRGHGTDLALVAGILGMDTDDPEIPNSLEIAHKRGIKIVWTIQKD
                     SNAPHPNTTKITVKNAHKTISVTGISIGGGNIQVTELNGFAVSLNMNTPTIIIVHQDI
                     PGMIALVTEALSRYGINIAQMNVTREKAGEKAIMIIEVDSRNCDEAIEEIRKIPHLHN
                     VNFFK"
     gene            2567..3139
                     /locus_tag="VQ862_001408"
     CDS             2567..3139
                     /locus_tag="VQ862_001408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000843467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HET3115748.1"
                     /translation="MKSITKKIKATLAGVAALFAVFSPSFVSAQESSTYTVKEGDTLS
                     EIAETHNTTVEKLAENNHIDNIHLIYVDQELVIDGPVAPVATPAPATYAAPAAQDETV
                     SAPVVSETVVSTVSGSEAEAKEWIAQKESGGSYTATNGRYIGRYQLTDSYLNGDYSAE
                     NQERVADAYVAGRYGSWTAAKNFWLNNGWY"
     gene            complement(3191..3511)
                     /locus_tag="VQ862_001409"
     CDS             complement(3191..3511)
                     /locus_tag="VQ862_001409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001811647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HET3115749.1"
                     /translation="MQRLEVYKNYQHLYDLQIAILLNLSTLYLYNQDKNMCKQICYTL
                     LEDAKNKKSYDRLAICYVRIGICTDDSKLIQKGFSLLELTEETSMLSHLKKEVEIYYQ
                     AKER"
     gene            3936..4220
                     /locus_tag="VQ862_001410"
     CDS             3936..4220
                     /locus_tag="VQ862_001410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001230165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
                     /protein_id="HET3115750.1"
                     /translation="MRKLVKIGVASLMVCSILASTSVLAVWVDGGQWNYGVGWSGNFG
                     YSDYLHSTRSHTATVKDGNKFSKDRAEAEAWARASIFKFPPTGMEYFYGF"
     gene            4275..6383
                     /locus_tag="VQ862_001411"
     CDS             4275..6383
                     /locus_tag="VQ862_001411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000723955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HET3115751.1"
                     /translation="MKKISHLCMLLLLLCTTFFVFNVNYTREVVRIQEMGKTVDSLDL
                     YLKDINEPAASVLRFFEDVSKEYKVSIIKTDSGDEVVKSGVFDKDTFPYQEFGISSLD
                     FTTDGEGVYSNKEISNKLGTIPTFLKAKPIQLMTFQTYIKDTSRSLNGRYTITSTQEM
                     DKDRIVQKWSDFFKIDQATLLEPTYKSAVEVINRDLLLSAIVFVLAILLLVLVTVYQP
                     MMEMKRVGVQKLLGFQDRAVLADVVKGNLYLLLGGALVINLGVFFLLDYKPKDLFPML
                     WLSHFLLLQLYLFISWLTYLLIQKMTISSLLKGFSSFKFGLLFNYLMKIGTTILLTVL
                     LVGVGKSLEQENKELDYQKQWISQGNYLTLETFQLNDNLWQEQLAGSGKALDYFYRFY
                     QDLVEKTQAGYVQSSSLPVKNFVQSEQIQQYQLTDTVDVYYANRNFLKSKGFKLPDTG
                     IKKVILMPASTKGEEDKNQLLGKLIAFHSMKYEEQQKRTIEEMDVEIAYYEGDWSFFP
                     YSDKRKENLSNPIISLVNDSDMMWDEKASLSTTGLNNPIKIENTVQHQKEITELVEKL
                     SDGNYLKFSSIQAIQQEKVDSYRDAVRNFNLLFALFGLLSMMISYFLLVITFLLKRRD
                     IITKKFMGWKLVDRYRPLLVLLLLGYSFPLLVLIFFAHAFLPLLLFAGFTCLDILFVL
                     VLASRMEKRSLVELLKGGIL"
     gene            6380..7021
                     /locus_tag="VQ862_001412"
     CDS             6380..7021
                     /locus_tag="VQ862_001412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000571330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3115752.1"
                     /translation="MIELENITKTIGGKVILDHLSLRIDQGDLVAIVGKSGSGKSTLL
                     NLLGLIDGDYSGRYEIFGQTNLAVNSAKSQTIIREHISYLFQNFALIDDETVEYNLML
                     ALKYVKLSKKDKLKKVEEILERVGLSSTLHQKVSELSGGEQQRIAVARAILKPSQLIL
                     ADEPTGSLDPENRDLVLKFLLEMNREGKTVIIVTHDAYVAQQCHRIIELGEGK"
     gene            7228..8034
                     /locus_tag="VQ862_001413"
     CDS             7228..8034
                     /locus_tag="VQ862_001413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001038484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HET3115753.1"
                     /translation="MNKMKKVLMTMFGLVMLPLLFACSNNQSAGIEAIKSKGKLVVAL
                     NPDFAPFEYQKVVDGKNQIVGSDIELAKAIATELGVELELSPMSFDNVLASVQSGKAD
                     LAISGVSKTDERSKVFDFSIPYYTAKNKLIVKKSDLTTYQSVNDLAQKKVGAQKGSIQ
                     ETMAKDLLQNSSLVSLPKNGNLITDLKSGQVDAVIFEEPVSKGFVENNPDLAIADLNF
                     EKEQDDSYAVAMKKDSKELKEAVDKTIQKLKESGELDKLIEDAFKASIEK"
     gene            8000..8470
                     /locus_tag="VQ862_001414"
     CDS             8000..8470
                     /locus_tag="VQ862_001414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012386596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate synthase"
                     /protein_id="HET3115754.1"
                     /translation="MRMPLKHPLKNRKKEKNMSKEKVILAYSGGLDTSVAITWLKKDY
                     DVVSVCMDVGEGKDLDFIHDKALKVGAVESYVIDVKDEFATDYVLVALQSHAYYEQKY
                     PLVSALSRPLISKKLVEIAHQTGATTIAHGCTGKGNDQVEYQIAVAKKANEAKK"
     gene            complement(8760..9080)
                     /locus_tag="VQ862_001415"
     CDS             complement(8760..9080)
                     /locus_tag="VQ862_001415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HET3115755.1"
                     /translation="MQRLEVYKNYQHLYDLRIAILLNLSTLYLYNQDKNMCKQICYTL
                     LEDAKNKKSYDRLAICYVRIGICTDDSKLIQKGFSLLELTEETSMLSHLKKEVETHYQ
                     PKKL"
     gene            9844..10224
                     /locus_tag="VQ862_001416"
     CDS             9844..10224
                     /locus_tag="VQ862_001416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SP_0115 family bacteriocin-like peptide"
                     /protein_id="HET3115756.1"
                     /translation="MELVLPNNYVALEQEEMMYLDGGGVGRNWWNSRGSFATVLDVGL
                     AIYSGGATIYSAYAIKKAISANRGAITRTLRSLIIKHVGSAAGHLVNTALNVALTVTG
                     FSLGGAIAYGADWADGSLDGYIFA"
     gene            10598..11656
                     /locus_tag="VQ862_001417"
     CDS             10598..11656
                     /locus_tag="VQ862_001417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3115757.1"
                     /translation="MKDDQKYLLAGLYSLLVAIFYFPLIESKGIFVSILMAVLLLYLI
                     YFIGTVIHIVIIKFIRKKSFKYLVLYPFTYDGSWRFQPINLLYFPEMVRDVIPINLVQ
                     EYCQGQPYGLLKKMLKRIRLSREIALLLATIIVYFFTHRILPLSVFTFMFSYILIFAQ
                     SYLGGNTAWIGNRRLIIDDEFEKILLSKSYIKEISSARYSEYLTCEYKNLTPIILLAI
                     FENLLDSYLLQNQSEVDLDIFYKVLPLLYKEKYTMGFNYFVSLNYLLYKVGFLGIIYD
                     NEALGDLSKQYLNRNISELQDGSFEGGIQDAVASKQIVVINEFIACLNSRCMPSQYDR
                     FFYKDRPYIFSRKSPIKR"
     gene            11971..12947
                     /locus_tag="VQ862_001418"
                     /pseudo
     CDS             11971..12947
                     /locus_tag="VQ862_001418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001837003.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            13324..13698
                     /locus_tag="VQ862_001419"
     CDS             13324..13698
                     /locus_tag="VQ862_001419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPH_0224 family bacteriocin-like peptide"
                     /protein_id="HET3115758.1"
                     /translation="MELVLPNNYVALEQEEMMYFDGGFSIPRWPVATAINIAFNDVLG
                     GGAISLVRNYIRNYGLRRVTSAIAGAAARYVGVRVANRVAGFALSAINGFAAWMSIGN
                     AITTIWANNDVNRRDPNLNALW"
     gene            13906..14808
                     /locus_tag="VQ862_001420"
     CDS             13906..14808
                     /locus_tag="VQ862_001420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3115759.1"
                     /translation="MIRKLIIFLLMLPLFVLWLELHVLVNNLLLNLESPLDFVISMSL
                     AFCSLILSKIVLDILYALKDLYKKEALITIFPFIFIGRKKVNVRFSPYFSFHRKSLSP
                     DDLRSRIIWSFILEIAIILVFILKIPFAIIMLTTIFFWTIMDINHLVFNKTEFLFNQN
                     KWQKEDSFESDLTKTLKDKIQKSELSYSDLMSLQLYDAMNQSTFLTDSELFEDILKKI
                     EDSHNTLLCTGLVELLLYEISISNNNNWQEKVDKIRIQLIRINQLDFFYYTSWLRQNF
                     DFCMNREYHKMKSRKLLLSNKKIV"
     gene            14864..15217
                     /locus_tag="VQ862_001421"
     CDS             14864..15217
                     /locus_tag="VQ862_001421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate lyase"
                     /protein_id="HET3115760.1"
                     /translation="MELVLPNNYVVIDEEEMMYLDGEAYLSKRACQGICAALAMSSGT
                     FIALAGAAVLTKKLINYIKVGGLGGWLIGAAAGVLATAAGKIAYYIGYGVLNRGCDIN
                     GNPYPWDGFISATVK"
     gene            15214..15942
                     /locus_tag="VQ862_001422"
     CDS             15214..15942
                     /locus_tag="VQ862_001422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3115761.1"
                     /translation="MSNVDKIRKIHIIVCWMYIFLSFRAIINDTEYFLLIFLAFIYSI
                     VSLPLYSVKNKIVSICLAINSILLMSFPILINKFFPESFLTYTVLISVFITELIIFHL
                     IGKDFDIKLTNEYKKISQFRSKVSQSPWIKYLEISSFILTIFPSILYGTVDNHVLTLI
                     FLIKICADTTIKFLFIRLFDTSTLMKRRIFFLFALDVIAYLFLGYLLVIQKAGYLFSV
                     LLLFSNFSVPFIKEKEFELFKNSK"
     gene            17074..17313
                     /locus_tag="VQ862_001423"
     CDS             17074..17313
                     /locus_tag="VQ862_001423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000770310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3115762.1"
                     /translation="MKLLDCILDYQERFNGKTCQVSTNYKYLETFKVNFCLTDLHHLF
                     DLHKITRDYASQTKPAIQAGVFILEDFRNILCTMM"
     gene            17863..>19123
                     /locus_tag="VQ862_001424"
     CDS             17863..>19123
                     /locus_tag="VQ862_001424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein"
                     /protein_id="HET3115763.1"
                     /translation="MNKKKMILTSLASVAILGAGFVASQPTVVRAEEAPVASQSKAEK
                     DYDAAKRDAENAKKALEEAKRAQKKYEDDQKKTEEKAKKEKEASKEEQAANLKYQQEL
                     VKYASEKDSVKKAKILKEVEEAEKEHKKKRAEFEKVRSEVIPSAEELKKTRQKAEEAK
                     AKEAELIKKVEEAEKKVTEAKQKLDAERAKEVALQAKIAELENEVYRLETELKGIDES
                     DSEDYVKEGLRAPLQSELDAKRTKLSTLEELSDKIDELDAEIAKLEKNVEYFKKTDAE
                     QTEQYLAAAEKDLADKKAELEKTEADLKKAVNEPEKPAEETPAPAPKPEQPAEQPKPA
                     PAPQPAPAPKPEKTDDQQAEEDYARRSEEEYNRLPQQQPPKAEKPAPAPKPEQPVPAP
                     KTGWKQENGMWYFYNTDGSMATGWLQNN"
BASE COUNT         6186 a         2932 c         3858 g         6147 t
ORIGIN      
        1 atctacaacc ttaaaacagt gttttgagca gcccgcagct agtttcctag tttgctcttt
       61 gattttcatt gagtattact tcattttctt ctgaaataga gttgtcgccc agtctatgct
      121 attgaaaata cgccaaaact tctaagggtt tgtgagcgat ataatcaggt tgatagttta
      181 gtagatctgc ttgctctcca aatccccaag tgacggccaa tttctgaata cctgtttctc
      241 gagctcccag catatcaaac ttggtatctc cgatgatgat ggcttgttct ggtgctagtt
      301 gatgtgtctg taaggcttgg tgaatgacat ctgccttatg gggtgcttca gggctagaac
      361 cataaatacc atcaaagaaa tgatggattt ccaagttttt ggccatgtct tgagcagtag
      421 atgtattctt tgtcgtggtg atgtagagtg gataactgct cgataactcc tcaagcaagt
      481 ctataatctg aggaaagagt tgagcttcat agatgccttt tgccttatag taagaacgat
      541 atatctgcat ggcttcagaa atttggtctt tggacaggca ggtcgcaaaa ctactttcga
      601 gaggtggtcc cataaaacca cgaatagttt tggcatcagg gctaggcacc cccagctctt
      661 taaaagtata ggtaaaggca ttgtgaatcc cgatagaact atcaacgagg gttccatcca
      721 aatcgaaaaa aatcgctgtg atagaggtca tggtttctcc tatttgataa gcttattctc
      781 cgaaaatctc tttttggagg cgacgaccag taggggtggt agcgagtcca ccttcagctg
      841 tttcacgaaa ggcagttggc atgcttgctc ctacttggta catggcatcg atcacttcat
      901 ccacagggat tttagattcg atacctgcca aggccatgtc tgctgcgatg aaagcaaagc
      961 tagctcccat ggcattacgt ttgacacagg gaacttcgac caaacctgca acagggtcac
     1021 agatgaggcc tagcatattt ttaatgacaa aggcaatagc ttgactggcc tgataaggtg
     1081 ttccacctgc agccagagtc aaggcggcag cactcatagc agaggctgaa ccaacttcag
     1141 cttgacaccc accctcagca cctgagatgg aggcattgtt tgcgatgact agtccaaagg
     1201 caccagcagc aaagaggaaa tccaattgtt gctcgtggct gaggtctaat ttttcaatag
     1261 cagcagtgag aacggaaggg agacaaccgg cacttcctgc ggtaggagta gcgcagacca
     1321 agcccatttt agcattgtgt tcattgactg cgatagcatt tcgggcagca gagagaatcg
     1381 tgtaatctga taaagttttt tcgtttttga tgtagtgatc caatttggca gcatctccac
     1441 ctgtcaggcc actacgagat ttattttcat tgaggccaag ttggacagag gctttcataa
     1501 cttccagatt gcgttccatg agaaggaaga cttcttcacg ttcgcgaccg gtcaattcaa
     1561 actctgttgt aatcatgagt tctgcgacat ttccttgaaa gtccagatct gcttgctcga
     1621 ccaattcttt gatagaataa aacatgcttc ctcctattta aagaaattga cattgtggag
     1681 atgagggatt tttcgaattt cttcgatagc ctcatcacag ttgcgactgt caacttcgat
     1741 aatcataatg gctttttcac cagctttttc acgagtgaca ttcatctggg cgatattgat
     1801 accatagcgg gaaagcgcct ctgtaacaag ggcaatcata cctggaatat cttgatgaac
     1861 gatgatgata gtcggtgtat tcatattgag agagacggca aaaccattga gttcggttac
     1921 ctgaatattt cctccaccga tagaaatacc agtcacgctg atggtcttgt gggcattttt
     1981 aacagtaatt ttagtggtgt tagggtgagg ggcattgctg tctttctgaa tggtccagac
     2041 aatcttgata ccacgcttgt gggcaatttc cagactattt ggaatttcag gatcatctgt
     2101 atccattcct aaaatacctg caacaagggc taggtctgtt ccgtgaccac gataggtctt
     2161 ggcaaatgag ttaaaaagtt ggaattcaac ttctgtcgga gtatcatcaa aaatggaaga
     2221 gacaatcttc ccaatacgaa cagcaccagc ggtatggcta ctagatgggc caatcataac
     2281 tggtccgatg atatcaaaga cagattgaaa acgaagtgat ttcatcagtt tccccttata
     2341 aaaattctta tctctattat atcaaagaat gaggggcttg gctttaattg tggatgaaaa
     2401 cctttctaat acctcaaata gcataaaaat agtatctttt atgacaaaaa acaccttatt
     2461 tagggaaata aaaaataatt ttgtaatatt tctacataaa agtgtcaaga aacggtaata
     2521 tttaaagggt atgatagaac tatagaaaga aggagaattt tcgaatatga aatcaataac
     2581 taaaaagatt aaagcaactc ttgcaggagt agctgccttg tttgcagtat tttctccatc
     2641 atttgtatct gctcaagaat catcaactta cactgttaaa gaaggtgata cactttcaga
     2701 aatcgctgaa actcacaaca caacagttga aaaattggca gaaaacaacc acattgataa
     2761 cattcatttg atttatgttg atcaagagtt ggttatcgat ggccctgtag cgcctgttgc
     2821 aacaccagcg ccagctactt atgcggcacc agccgctcaa gatgaaactg tttcagctcc
     2881 agtagtaagt gaaacagttg tttcaactgt aagcggatct gaagcagaag ccaaagaatg
     2941 gatcgctcaa aaagaatcag gtggtagcta tacagctaca aatggacgtt atatcggacg
     3001 ttaccaatta acagattcat acctgaacgg tgactactca gctgaaaacc aagaacgtgt
     3061 agcagatgcc tacgttgcag gacgttacgg ttcatggact gctgctaaaa acttctggct
     3121 taacaatggc tggtattaag aactaacgaa caaataatat gtaaagagtc gaggaaatcc
     3181 ctcggctttt ttatctttcc ttcgcttggt aatagatctc tacttctttt ttgagatgag
     3241 acagcataga agtttcctcg gttagctcca gaagggagaa ccctttttgg ataagtttag
     3301 aatcgtctgt acaaatccca atacggacat agcagatagc cagcctatcg tagcttttct
     3361 tattcttggc gtcctctagt aaagtgtagc agatttgctt acacatgttt ttatcttgat
     3421 tgtatagata gagtgtggaa aggttgagca ggattgctat ttgcaagtca tataaatgtt
     3481 gatagttttt atagacttct aagcgttgca agattttctc ggattattga caaataaacg
     3541 gacattctga tagacgattg ccctagcggc ttagtgtaaa ctttacaaat ttggcttgta
     3601 atttttttat aaaattcact tcagttactt gacagttatt atattttcac ttattatata
     3661 gataaaagga tgagatggga gtttaaaaat ttgaaagcgc tatccatatt gtttattgga
     3721 ctgattcttg agtaatagtt agagtgtgct taatactact ctggttgttc aaggacctga
     3781 tacagaagcg caccattctc tcggttaaga gtaagttcgt tgttaaaaaa tgaaatgaga
     3841 tagaaggaag gtgagtccaa tggactacga tacttgttga taaattacta tagctgtttt
     3901 tacggaagag ctctcgataa taggagaaat aaatcatgag aaaattagtt aaaattggtg
     3961 ttgcatcttt aatggtatgt agtatacttg cttctacaag tgttttggca gtatgggttg
     4021 atggtggtca atggaactat ggagtaggat ggtcaggaaa ttttggttat tctgattatt
     4081 tacattctac tcgctctcat acagcaactg ttaaagatgg aaataaattc tctaaggatc
     4141 gtgcagaagc tgaggcatgg gctcgggctt caatcttcaa attcccacca acgggaatgg
     4201 aatatttcta tggattttaa ttaaaattct ccctcccctt ttggagaggg agtttcttca
     4261 cgggaggtat ctctatgaaa aaaatcagtc atctttgtat gttactcctg cttctgtgta
     4321 ccactttttt tgtttttaat gtaaactata cacgagaagt ggttcggatt caagaaatgg
     4381 gaaagactgt agattctttg gatttgtatt tgaaagatat taacgaacct gcagcgtctg
     4441 ttcttcgatt ttttgaggat gtatcaaagg agtataaagt ctccatcatc aaaacagaca
     4501 gtggtgatga ggtggtcaag tctggtgttt ttgataaaga taccttcccc taccaagagt
     4561 ttgggatttc ttctcttgat tttaccacag atggtgaagg agtctatagt aataaagaaa
     4621 tttccaataa acttggtacg attccgacct ttctaaaagc caaacctatt cagcttatga
     4681 cttttcaaac ctatatcaag gatacatctc gtagtttaaa tggtcgctat acgataactt
     4741 ctacacaaga gatggacaag gataggattg tacagaaatg gagcgatttt ttcaagatag
     4801 accaggctac cttgctagag ccgacctaca aaagtgcagt ggaagtcata aatcgagatt
     4861 tgcttttatc tgccattgtt tttgtcttgg ctattttgct tcttgtgtta gtgacagtgt
     4921 atcaaccgat gatggagatg aaaagagttg gggtacaaaa attacttggt tttcaagata
     4981 gggctgtttt agctgatgtt gtaaaaggca acctttacct cctcctaggt ggggctcttg
     5041 tgatcaatct aggcgtgttt ttcttgcttg attataagcc aaaagatttg tttcctatgc
     5101 tgtggttgtc tcattttttg ctgttgcagc tttatctctt tatcagttgg ttgacttacc
     5161 tcttaatcca aaaaatgaca atcagctctc tgctgaaagg tttttcatct ttcaaatttg
     5221 gtctactctt taattatttg atgaaaattg gaactaccat tttactgaca gtcttgctag
     5281 ttggggtagg aaaaagtttg gagcaagaaa acaaagagtt ggattaccag aaacagtgga
     5341 tcagccaagg aaattatctg accttagaaa ctttccaact caatgataac ttgtggcaag
     5401 agcagttggc aggctcaggg aaggcattgg attatttcta tcgattttat caggatttgg
     5461 tagaaaaaac gcaggcgggc tatgtgcaga gtagcagtct tcctgtaaaa aattttgtcc
     5521 aatcagaaca gattcagcaa tatcagttaa cagatacggt ggatgtttac tatgccaatc
     5581 gcaattttct aaagagcaag ggattcaagc taccagatac cggtattaaa aaagttattt
     5641 tgatgccagc aagtacgaaa ggtgaagaag ataaaaatca gctcttgggg aagttaattg
     5701 cctttcattc gatgaagtat gaagagcagc aaaaacgaac gatagaggag atggatgtcg
     5761 agattgccta ttatgaagga gattggtcat ttttcccata tagtgataag cgaaaggaaa
     5821 atctctccaa tccaattatt agcttggtca atgattctga tatgatgtgg gatgagaaag
     5881 cctccctgtc aacaactggc ttaaataatc cgattaaaat tgaaaatacg gttcaacatc
     5941 aaaaagagat tacagagtta gttgagaaat tgtcagatgg aaattattta aaattttcat
     6001 ctattcaagc cattcaacaa gagaaagtgg attcttatcg agatgctgtt cggaatttta
     6061 acctactctt tgctttgttt ggtctcctta gcatgatgat ttcctacttc ttactagtaa
     6121 taactttctt attgaagcgc agggatatca ttaccaagaa gtttatgggg tggaaactgg
     6181 tcgatcgcta ccgtcctctc ctcgttctgc tcttgctggg ctatagtttc cctcttctag
     6241 tcttgatttt ctttgcccat gcgttcttgc cacttctgct gtttgcaggc tttacatgtt
     6301 tggatatact atttgtgcta gtcttggctt ctaggatgga gaaaagaagt ctagtagagt
     6361 tattgaaagg gggcatctta tgattgagtt ggaaaatatt accaaaacca ttgggggaaa
     6421 agtgattttg gatcacttgt ctctcaggat tgatcagggg gatttggtag ctattgttgg
     6481 aaaaagtggt agtgggaagt cgaccttgtt aaatttatta ggtttgatag atggtgatta
     6541 tagtggacgg tatgagattt ttggtcagac aaatctagcg gtcaattctg ctaagtcgca
     6601 aacaataatc cgtgaacata tctcttatct gtttcaaaat tttgccctga ttgatgatga
     6661 aacggtcgag tacaatctca tgctggcgct gaaatatgtg aaattgtcta agaaagacaa
     6721 gctcaaaaag gtggaagaga ttttagagag agtaggtttg tcatctactt tgcatcaaaa
     6781 ggtttccgag ttgtctggtg gcgaacaaca acgaattgca gttgctagag ccatcttaaa
     6841 acccagccag ctgattttag ccgatgaacc aacaggttcg ctagatcctg aaaatagaga
     6901 tttggtcttg aagtttctct tagagatgaa tcgcgagggg aaaacagtca ttattgtgac
     6961 ccacgatgct tatgtagccc aacaatgtca tcggatcatt gaattgggcg aggggaaatg
     7021 agtttgttca gctctttttg actgactgaa tactcatgtt tttcagagag gaatagcata
     7081 aatacgccta gaaatgacat ttttatgtag tatttctagg tttttttgtt tcaaattgaa
     7141 aatttttcca atttaggctt gacaaaggat gaagataggt gtattattta tacaaccaaa
     7201 aagaataaac ataaaggaga ctttgttatg aataagatga agaaggtgtt gatgacgatg
     7261 tttggtttag tgatgctccc cctactattt gcttgtagca acaatcaatc ggctggaatt
     7321 gaagccatca agtccaaagg aaaattggtt gtagccctca atccagattt tgctccattt
     7381 gaataccaaa aagtggttga tgggaaaaat cagattgtgg gttcagatat cgaattagcc
     7441 aaggctatcg caacagaact aggtgtcgaa ttggaactat ctcccatgag ttttgataat
     7501 gtactggcta gtgttcaatc aggaaaagcc gaccttgcca tatcaggtgt ttctaagaca
     7561 gatgaacgga gcaaggtgtt tgacttttcc attccctact atactgcaaa aaataaactc
     7621 attgtcaaaa aatctgactt gactacttat cagtctgtaa acgacttggc gcagaaaaag
     7681 gttggagcgc agaaaggttc gattcaagag acgatggcga aagatttgct acaaaattct
     7741 tccctcgtat ctctgcctaa aaatgggaat ttaatcacag atttaaaatc aggacaagtg
     7801 gatgccgtta tctttgaaga acctgtttcc aagggatttg tggaaaataa tcctgattta
     7861 gcaatcgcag acctcaattt tgaaaaagag caagatgatt cctacgcggt agccatgaaa
     7921 aaagatagca aggaattgaa agaggcagtc gataaaacca ttcaaaagtt gaaggagtct
     7981 ggggaattag acaaactcat tgaggatgcc tttaaagcat ccattgaaaa atagaaagaa
     8041 ggaaaagaac atgagtaaag aaaaagtaat tttggcctat tctggcggtt tggacacatc
     8101 agttgctatt acctggttaa agaaagacta tgatgttgtt tcagtttgta tggatgtggg
     8161 tgaagggaaa gacttagact tcatccatga taaggctctc aaggttgggg cagtcgaatc
     8221 ttatgtcatt gatgtcaagg acgaatttgc tacagattat gtgctagtgg ctcttcagtc
     8281 acatgcctat tatgaacaaa agtacccctt ggtatctgcc ttgagccgcc ctcttatttc
     8341 taaaaaatta gttgaaatag cgcatcagac aggagcgact acaattgctc atggctgtac
     8401 cggtaagggg aatgaccaag tcgaatacca gattgcagtc gctaagaaag cgaatgaagc
     8461 taaaaagtga tggagtgatg ggttcagaat aagaggttgg tcgattggta gcctctttct
     8521 tgtcgttgaa aaagtgagat atattgactt ttgaaaaaaa tgtcataatt gagttgggat
     8581 aaacgtaaaa gtcatacttt ctcgttaaat cgttcggcga ttcatggtga catggacaca
     8641 tagtagtaaa cacactatgt ggcttggcag agctaaaaac ttctggctta acaatggctg
     8701 gtattaagaa ctaacgaaca aataatatgt aaagagtcga ggaaatccct cgactttttt
     8761 tataatttct ttggttgata atgggtctct acttcttttt tgagatgaga cagcatagaa
     8821 gtttcctcgg tcagctctag gagtgagaac cctttttgga taagtttaga atcgtctgta
     8881 caaatcccaa tacggacata gcagatagcc agcctatcgt agcttttctt attcttggcg
     8941 tcctctagta aagtgtagca gatttgctta cacatgtttt tatcttgatt gtatagatag
     9001 agtgtggaaa ggttgagcag gattgctatt cgcaagtcat ataaatgttg atagttttta
     9061 tagacttcta agcgttgcaa gattttctcg gattattgac aaataaacgg acattctgat
     9121 agacgattgc cctagcggct tagtgtaaac tttacaaatt tggcttgtaa tttttttata
     9181 aaattcactt cagatacttg acagttatta tattttcgct tatgcttatt atatagataa
     9241 aaggacggga taggagttta aaaatttgaa agcgctatcc ataataataa cgcataattt
     9301 tctccttttc gtgaaaaaag ttaacgtaat tttaaaatga gcttaataag aggtactatg
     9361 taggtagaaa ataaagatag gagaaaaagt atgaataaaa aaatattttg tattctggta
     9421 tgtattatat cattgattag tctagctata atctttccat ggggctggtc gatataatgt
     9481 aagggagctt gagttgttag tggaggataa aatgttaaga gtaatagtag ttattcaatc
     9541 tttagtaata atactgcttg ctgttgcttt attattatct cggaaaaact ttgattcgtt
     9601 aaatgttgtt cttataatga tgatcgtatc acaattgttg ttattagtat atttgataaa
     9661 atcagggaat cagtgattag ctgttatttg aattaagtaa actgttaagc ttcaagcagt
     9721 aactggtttt aaatatttaa aataagataa aggaaggaag tctaatttag gtaactaaac
     9781 aaagcctgcg atcacttgtt aggaaactat cctaaccatg cttaataaaa aaggagaaaa
     9841 taaatggaac tcgtattacc aaataattat gttgctcttg agcaagaaga gatgatgtat
     9901 cttgatgggg gtggtgttgg tcgtaactgg tggaatagta gaggtagttt tgcaacagtt
     9961 ttggatgtag gtttggccat ctatagtggt ggtgcaacaa tttattctgc ttatgcgata
    10021 aaaaaagcta tctcagctaa tagaggggct attacgagaa cattacgtag tttaataatt
    10081 aaacatgtag gtagtgcagc tggccattta gtcaatactg cactaaacgt tgcactaact
    10141 gttactggat tttcactagg tggagcaatc gcatatgggg ctgattgggc tgacggtagc
    10201 ttagatggtt atatttttgc ttaaaatgaa acattttttt gcaggaattg gtgaaattca
    10261 ttttttgtta tttttattat atctaagcat gtctgctagt ccaattattg gactagtgat
    10321 tggatatact aaaataaatc taataaattc tattattata gctcttggta tgatattggc
    10381 attaattttg gtattatcaa gagtgtatag aaaatatttt tatagagacg atgatgacta
    10441 aagtttttat caataatttg ggctccttgt caactgtagt gggttgaaga aaagctaacg
    10501 tctggggaag gggttaaagc tttgctttat caaatattga cttacagagt tgctctattg
    10561 tattgatgta ttcttagtaa ataatatggt gttttgaatg aaagatgatc agaaatattt
    10621 attagcggga ctttattcgc ttctagttgc aatattttat tttccattga ttgagtccaa
    10681 ggggattttt gtaagtatat tgatggcggt tttactttta tatttaatat acttcattgg
    10741 aacagtcatt catattgtga taattaagtt tataagaaaa aaatctttta agtatttggt
    10801 tctatatcca tttacttatg atgggagctg gagatttcaa cctataaact tactctactt
    10861 tccagaaatg gtgagagatg tcattccgat taatttagtt caagaatatt gccaaggaca
    10921 accttacggg ctgttaaaaa agatgctgaa aagaattcga ttgtcacgag agatagcttt
    10981 actcctggct accattatcg tctatttttt tacgcataga attctacctc tttcagtatt
    11041 tacgttcatg ttttcttaca tattgatatt tgcacaatct tatttgggtg gtaatactgc
    11101 ttggattgga aatagaagat taataataga tgatgaattt gaaaaaatct tgctttcaaa
    11161 aagttatata aaagaaatat catctgcacg atactcggaa tacttgacat gtgaatacaa
    11221 aaaccttaca ccaatcatat tgttagctat ttttgaaaat ttacttgact cctacttgct
    11281 tcagaatcag agtgaggttg acttagatat tttttataaa gttttacctt tgctttataa
    11341 agaaaaatat actatgggat tcaattactt tgtaagttta aattatttac tatataaggt
    11401 tggatttttg ggaatcattt acgataatga agcattagga gatttgtcaa aacaatattt
    11461 aaacagaaat atttcggaat tacaagatgg ttctttcgag ggcggtatac aagatgctgt
    11521 tgcctctaaa caaatagtag ttataaatga atttatagct tgtttaaatt ccagatgcat
    11581 gccatcccaa tatgatagat ttttttataa agatagacct tatatttttt ccagaaagag
    11641 tcctattaag aggtgaaaat ttgttacatt tggattaaca agtgtcctag ggattagaaa
    11701 taactctagt atagctagat atttttgagt aactagaaat atcattaggc tacccatatg
    11761 attgccagaa aagatggctg atgaatctta tttatactgt tgcagtaggc gttgtctagg
    11821 ataaataagc tatcttgatg ggggagattg gaataatttt agtagaaaca ttaaaggatt
    11881 atgggcaagt agcacaggat taggtgatgc aatgtgctaa gttggcttgg tgttagcagt
    11941 agtattattt aacaatggaa agtagactaa atgaaaaata aacgttattt ttttgacaca
    12001 attttaatga ttttactact tataagcacg atattttgtg tcagcccagt atttataaaa
    12061 ttggacatct taggaactcc ctctcatgcc atcttaacct ttgtattggc gataccgtta
    12121 ttctatattt tgtctcaatg cttacatact ttgctattac tagtttcctc aatcttttgt
    12181 aaattaagac caatttattt ttattttata tttgtgatca ttataggagc taggaaatac
    12241 tatcgaattc tctttcacca actaatggga tttagtccag gaatagcagt gttttataag
    12301 gagagtcaaa caactaagaa tctgtttaaa ttttactact tcttgtactt tacaacacta
    12361 atttcatact attttttctt tacttttgtg tatgacaaac cgttgctttt gcctcttatt
    12421 ccattttcta ttatcatagc attagtacaa aaactttata gaattgagaa tcagcaatta
    12481 tttctgttaa aatcaaaggt actaacaata ctggaatcta agaagaattg tgagtttaat
    12541 cttcaggatt atcatgaaat ttggaaattg caatcaaaat ctgagttgcc atgcgtggct
    12601 ttatcttata tcagtttgat caagccatat ctttcagaga gcgtgcgtga acaaattgat
    12661 ttattagaag ttaagcgatt taaaaaaata aatcatccaa tatcacttta tggtatgttg
    12721 gatgttataa aattaaatct atatttacgg cattataatg aaaaaataaa tatgaatcaa
    12781 tgttaaagaa aattttagag gtaagaccag actttgtttt aatcgagcag aatattgatg
    12841 atagtttaaa tagctcgcaa ccattatctt tatctttagc tatttcagaa atccaacttt
    12901 tgcttgaagt gtatataggg atcaaacatg tttcaattag gagataaaac tagaataaca
    12961 tttgctatta taggggcaag ttgcatatta gtcagtatgt atcttatacc tctcattaac
    13021 acggataata aattttggga aatactttta tttataatag gtgtattgct aattggaatt
    13081 gcgttactaa gtcaaaaaaa ataaattttg aaatagtatt agtgagttcg caatcattta
    13141 ttgctagtgg tttagaactg ttaagtttca agcaataatt ggttttaaac cttaggtaac
    13201 ctataaaaac aaataaggta gagaaaggat atcttattta ggtaactaag tactataaac
    13261 acagtcgaca atcacttgtt aggaaaccat cctaactatg cttaataaaa aaggagaaaa
    13321 taaatggaac tcgtattacc aaataattat gttgctcttg agcaagaaga gatgatgtat
    13381 tttgatgggg gattttctat tccgagatgg cctgttgcaa cagccattaa tatagctttt
    13441 aatgatgtct taggtggagg agcaatcagt ctagttagaa attatattcg taattatggt
    13501 ttgcggcgag ttacaagcgc aattgctgga gcagctgcaa gatatgttgg ggtacgagtt
    13561 gcaaatagag tggcaggatt tgcactgtct gctattaatg gatttgcagc ttggatgtca
    13621 attggcaatg ctattacaac aatctgggcc aataatgatg taaataggag agacccaaat
    13681 ttaaacgcct tgtggtaact agatatgggt attaaaatgg aaaaaatttt tgttattatt
    13741 ttttttgtat gtctatttat atcatccata acttttttag cctatgattt tgttagcgaa
    13801 gaaataaaaa agttgattat ttggatgaat gtcgtttttt tgattttaat catagcaatg
    13861 ataatttatc caaaattaag aaaatgataa ggacactgta aaattatgat acgtaaacta
    13921 atcatttttt tattaatgct ccctcttttt gtcttgtggc tagagttgca tgtcctagtg
    13981 aataacttac tattgaatct agaatctccc cttgattttg tgattagtat gagtcttgct
    14041 ttctgtagtt tgattttatc aaaaatagtt ttagacatac tatacgcatt gaaagatttg
    14101 tacaagaaag aagctcttat tacgattttt ccttttattt ttataggcag gaagaaagta
    14161 aatgtgaggt tctcgcccta tttttcattc catcgtaaaa gtttgtcgcc tgatgattta
    14221 agatctagga ttatatggag ttttattctt gaaattgcta ttatcctagt atttatttta
    14281 aaaattcctt ttgcaatcat catgcttact acaatatttt tctggactat aatggatatc
    14341 aatcatctcg tttttaataa gacggaattt ctttttaatc aaaacaaatg gcaaaaagaa
    14401 gattcgtttg aaagtgattt gacgaaaacg ttaaaggata agatacaaaa atcagagcta
    14461 agttattctg acttaatgtc tcttcagctg tatgatgcga tgaaccaatc caccttttta
    14521 acggatagtg aactttttga ggatattttg aaaaaaatcg aagattctca taacaccctt
    14581 ctgtgtacag gtcttgtcga gttactgctg tatgaaattt ctattagtaa caataacaac
    14641 tggcaagaaa aggttgataa aattagaata cagctcatca gaatcaatca attagatttt
    14701 ttctattata caagttggtt aaggcaaaat tttgatttct gtatgaatag agagtatcat
    14761 aaaatgaaat ctcggaaatt attactgagt aataaaaaga tagtttaagt tcgtcctatt
    14821 tgtaaaacaa atgaaacaat ttcaactaag gaggagaaaa caaatggaac ttgtattacc
    14881 aaataattat gttgtgattg atgaagaaga aatgatgtat cttgatgggg aagcttattt
    14941 aagcaagcgt gcttgtcaag gaatttgcgc agctttagct atgagttcag gaacttttat
    15001 agcattagct ggagctgcag ttttaaccaa aaaactaata aactatatta aggttggagg
    15061 tcttggaggc tggcttattg gtgcagcagc aggtgtattg gctacagcag cagggaaaat
    15121 agcttactat attggatatg gtgttcttaa tagaggttgt gatattaacg ggaaccctta
    15181 tccttgggat ggattcatat ctgcgacagt aaaatgagta atgtagataa gattcgaaaa
    15241 atacacatta tcgtatgttg gatgtatata tttttatcat tcagggcgat tataaatgac
    15301 acggagtatt ttttgcttat ttttttagct tttatctact caatagtatc actacctcta
    15361 tattctgtga aaaataaaat agtatctatc tgtctagcca taaattcgat tctgttaatg
    15421 agtttcccca ttttaatcaa taagtttttc ccagaaagtt ttttgactta taccgtatta
    15481 ataagtgttt ttattacaga gttgataatt tttcatttaa ttgggaaaga ttttgatatt
    15541 aaattgacta acgaatataa gaaaattagt cagtttagaa gcaaggtgtc tcaatctcct
    15601 tggataaaat atttagagat ttctagtttt atattaacta tatttccatc tattctttat
    15661 ggtacagttg ataatcatgt actgactctt atctttttga taaaaatttg tgcagatacc
    15721 acgataaaat ttttattcat cagattattt gacacaagta ctttaatgaa gaggagaata
    15781 ttttttcttt tcgcattgga tgttatagct tacttatttt taggatatct tttagtgatt
    15841 caaaaagcag gctatttgtt ttcggtttta cttctttttt ctaatttttc agttccattt
    15901 atcaaagaaa aggaattcga attatttaaa aatagcaagt aatagaaaca taggttaaat
    15961 cttagaacgg cttaaaatca gatatgataa agggaaatag tcttatctag gtaactaagt
    16021 gctacaaaca caatcgagga tcacttgtta ggattacatt ttaatcatgc ttaataagaa
    16081 tggagaattc ctatggggat tgtattactc tgaagtttcg aataccttag ttctcgtgat
    16141 tttgagctat tctaggttta gaatccttca gaatgtaaaa ttttaagcag tcaaagactt
    16201 agaatagccc gaaaacattt attttatagc aattctaggc ttagaattgc tcatatatat
    16261 gtatttgagc tgctcgatag ttaggatagc tctattctga gaaatctgag ctatcaatgc
    16321 ttcagaatag tattcgccaa tggtttttat tgaagaggtg attgttttat gatagtctaa
    16381 aataaaactg atttaataga gtaaatggag aatcgttaca tgaaacattt ttttgcagga
    16441 attggtgaga taaaacttgt tggctactta ttgtatatat gtgtaggact agctcctctt
    16501 tttcatatat atgtcatagg ttcggaactg agttttgtga aaatagtgtt atctattttg
    16561 ggagttatat ttgtaagtat gttaactatt gctcgaattt atcggacttt tctataaaga
    16621 atagtttgga cttgaactgt atctaaaaac agaggttggt cgattatcag cctctttctt
    16681 gtcgttgaaa agagtgagat atattgactt ttgaaaaaag atgtcataat tgagttggga
    16741 taaatctaaa aataatatag tagattgaat ctggaatagt ccgttatgac tgttaaaata
    16801 tttctagaaa ttaatttgac tttcctaatc gatttgttca tatcttgttt caatctacta
    16861 tactttctcg ttaaaccgtt cggcaattca tggtgacatg gacacatagt agtaagcaca
    16921 ctatgtggct tggcagatct aaaaactgtt cccttgcgat aagcctaata agcacaacat
    16981 agggagttag agaagccgac tctaatcaac cactttgggc agtagtgaga actgccccgt
    17041 gctttttatt ttgagaaaat atggagtttg tcgttgaaat tacttgattg tattttggat
    17101 tatcaagaaa gattcaatgg aaaaacatgt caagtatcaa cgaattataa gtatttagag
    17161 actttcaaag tgaatttttg cttgactgat ttacatcatt tatttgactt acacaaaatc
    17221 acacgagatt atgctagtca aacaaaacct gctattcaag ctggtgtttt tattttagaa
    17281 gattttagaa atatcctatg tacaatgatg taatcgaaag gatatcttta tgtgagttta
    17341 tcggcgatat cttctatatc taagctagca agttgttgca tcgtagctaa ggatttatct
    17401 aaaaatacta tgaaattgga cgtcatattt tttgaggata aaaataaaag atccgcagtt
    17461 ttaggtttac gaagagacaa aagcggagta tttaaaccag ttactctaca ttttacaagc
    17521 gctaagaaat atgctaaagt tcgtaaaaca gatgtgaaag aaatgaaatg gctataaaga
    17581 ttgtccgcag gcttaagctt gcgttttttg ttgtttaacg aaattaaaaa acaagctctc
    17641 tcatcggaaa tgtttttata ggaatgaagg aagatgatgc tatgtttaaa aagagaatcg
    17701 aaaagggcaa aagtagtgtc tttatctttt tggagtagaa gcttatgata tagaaatttg
    17761 taataaaaat gtaatataaa acatttgaca aatatttacg gggggagtat acttaatata
    17821 agtatagtct aaaaatgact atcagaaaag aggtaaattt agatgaataa gaaaaaaatg
    17881 attttaacaa gtctagccag cgtcgctatc ttaggggctg gttttgttgc gtctcagcct
    17941 actgttgtaa gagcagaaga agcccccgta gctagtcagt ctaaagctga aaaagactat
    18001 gatgcagcga agagagacgc tgagaatgcg aaaaaagctt tagaagaagc aaaacgtgcg
    18061 cagaaaaaat atgaggatga tcagaagaaa actgaggaga aagcgaaaaa agagaaagaa
    18121 gcttctaaag aggaacaagc tgcaaatctg aaatatcaac aagagttggt taaatatgct
    18181 agtgaaaaag attcagtaaa aaaagctaaa attctgaaag aagtggagga agctgagaaa
    18241 gagcataaga aaaaacgagc agaatttgag aaagttagat cagaggtaat tcctagcgcg
    18301 gaagagttaa aaaagactag acaaaaagca gaagaggcta aagcaaaaga agcagaactt
    18361 attaaaaaag tagaagaagc tgagaaaaaa gttactgaag ccaaacaaaa attggatgct
    18421 gaacgtgcta aagaagttgc tcttcaagcc aaaatcgctg agttggaaaa tgaagtttat
    18481 agactagaaa cagaactcaa agggattgat gaatctgact cagaagatta tgttaaagaa
    18541 ggtctccgtg ctcctcttca atctgaattg gatgccaaac gaactaaact atcaacactt
    18601 gaagagttga gtgataagat tgatgagtta gacgctgaaa ttgcaaaact tgaaaaaaat
    18661 gtagaatatt tcaaaaaaac cgatgctgag caaactgaac aataccttgc tgcagctgaa
    18721 aaagacttag ctgataaaaa agctgaattg gagaaaactg aagctgacct taagaaagca
    18781 gttaatgagc cagaaaaacc agctgaagaa actccagctc cagcaccaaa accagagcaa
    18841 ccagctgaac aaccaaaacc agcgccggct cctcaaccag ctccagcacc aaaaccagaa
    18901 aaaacagatg atcaacaagc tgaagaagac tatgctcgta gatcagaaga agaatataac
    18961 cgcttgcccc aacagcaacc gccaaaagca gaaaaaccag ctccagcacc aaaaccagag
    19021 caaccagttc ctgcaccaaa aacaggctgg aaacaagaaa acggtatgtg gtacttctac
    19081 aatactgatg gttcaatggc gacaggatgg ctccaaaaca acg
//
LOCUS       DAVBOD010000038        19093 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 640-05
            SAMEA1012484-rid20186543.denovo.038, whole genome shotgun sequence.
ACCESSION   DAVBOD010000038 DAVBOD010000000
VERSION     DAVBOD010000038.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012484
            Sequence Read Archive: ERR059358
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 19093)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19093)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979948.1
            Genome Coverage       :: 595x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:03:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,266
            CDSs (total)                      :: 2,219
            Genes (coding)                    :: 2,091
            CDSs (with protein)               :: 2,091
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 71 of 128
            Pseudo Genes (incomplete)         :: 50 of 128
            Pseudo Genes (internal stop)      :: 33 of 128
            Pseudo Genes (multiple problems)  :: 22 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19093
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012484-rid20186543.denovo.038"
                     /strain="NIG 640-05"
                     /db_xref="taxon:1313"
     gene            complement(255..1223)
                     /locus_tag="VQ862_001425"
     CDS             complement(255..1223)
                     /locus_tag="VQ862_001425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000081018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HET3115764.1"
                     /translation="MSQLYDITIVGGGPVGLFAAFYAHLRQAKVQIIDSLPQLGGQPA
                     ILYPEKEILDVPGFPNLTGEELTNRLIEQLNGFDTPIHLNETVLEIDKQEEEFAITTS
                     KGSHLTKTVIIAMGGGAFKPRPLELEGVEGYENIHYHVSNIQQYAGKKVTILGGGDSA
                     VDWALAFEKIAPTTLVHRRDNFRALEHSVQALQKSSVTIKTPFAPSQLLGNGKTLDKL
                     EITKVKSDETETIDLDHLFVNYGFKSSVGNLKNWGLDLNRHKIIVNSKQESSQAGIYA
                     IGDCCYYDGKIDLIATGLGEAPTAVNNAINYIDPEQKVQPKHSTSL"
     gene            1359..2216
                     /locus_tag="VQ862_001426"
     CDS             1359..2216
                     /locus_tag="VQ862_001426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001867651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00159 family protein"
                     /protein_id="HET3115765.1"
                     /translation="MNFQQLSNLQYWTSLFASPWTIAINLIDILIVAYILYHFTKAIA
                     GTKIMILVRGVLVFILAQILANMIGLTTISWLINQIITYGVIAAVVIFSPEIRTGLER
                     LGRATDFFSNAPISAEEQMIRAFVKSVEYMSPRKIGALVAIQRVRTLQEYISTGIPLD
                     AKISAELLINIFIPNTPLHDGAVIIKEERIAVTSAYLPLTKNTGISKEFGTRHRAAIG
                     LSEVSDALTFVVSEETGGISITYNGRFKHNLTLDEFETELREILLPKEEVGLSFKERL
                     LGGWKHEKK"
     gene            2203..2982
                     /locus_tag="VQ862_001427"
     CDS             2203..2982
                     /locus_tag="VQ862_001427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbbR-like domain-containing protein"
                     /protein_id="HET3115766.1"
                     /translation="MKKNSLYIISSLFFACVLFVYATATNFQNSTSARQVKTETYTNT
                     VTNVPIDIRYNSDKYFISGFASEVSVVLTGANRLSLASEMQESTRKFKVTADLTDAGV
                     GTIEVPLSIEDLPNGLTAVATPQKITVKIGKKAQKDKVKIVPEIDPSQIDSRVQIENV
                     MVSDKEVSITSDQETLDRIDKIIAVLPTSERITGNYSGSVPLQAIDRNGVVLPAVITP
                     FDTIMKVTTKPVAPSSSTSNSSTSSSSETSSSTKATSSKTN"
     gene            3006..4358
                     /locus_tag="VQ862_001428"
     CDS             3006..4358
                     /locus_tag="VQ862_001428"
                     /EC_number="5.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglucosamine mutase"
                     /protein_id="HET3115767.1"
                     /translation="MGKYFGTDGVRGEANLELTPELAFKLGRFGGYVLSQHETEAPKV
                     FVGRDTRISGEMLESALVAGLLSVGIHVYKLGVLATPAVAYLVETEGASAGVMISASH
                     NPALDNGIKFFGGDGFKLDDEKEAEIEALLDAEEDTLPRPSAEGLGILVDYPEGLRKY
                     EGYLVSTGTPLDGMKVALDTANGAASTSARQIFADLGAQLTVIGETPDGLNINLNVGS
                     THPEALQEVVKESGSAIGLAFDGDSDRLIAVDENGDIVDGDKIMYIIGKYLSEKGQLA
                     QNTIVTTVMSNLGFHKALNREGINKAVTAVGDRYVVEEMRKSGYNLGGEQSGHVILMD
                     YNTTGDGQLSAVQLTKIMKETGKSLSELAAEVTIYPQKLVNIRVENVMKEKAMEVPAI
                     KAIIEKMEEEMAGNGRILVRPSGTEPLLRVMAEAPTTEEVDYYVDTITDVVRAEIGID
                     "
     gene            4432..4806
                     /locus_tag="VQ862_001429"
     CDS             4432..4806
                     /locus_tag="VQ862_001429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001050081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1149 family protein"
                     /protein_id="HET3115768.1"
                     /translation="MNLKREQEFVSQYHFDARNFEWENENGAPETKVDVNFQLLQHDQ
                     ENQVTSLIVILSFMIVFDKFVISGTISQVNHIDGRIVNEPNELNQEEVETLARPCLNM
                     LNRLTYEVTEIALDLPGINLEF"
     gene            4808..5656
                     /locus_tag="VQ862_001430"
     CDS             4808..5656
                     /locus_tag="VQ862_001430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HET3115769.1"
                     /translation="MKLAVFTDSSAYLSAETLQREDLFVLDIPVNIDGEEYVEGINLS
                     AEEFYQKMAQASELPKTSQPSIAKLDEILTSLKEQGYTHALGLFLSSGISGFYQNIQY
                     MVDDYEGLTIAFPDTLITSAPLGIMVESVFNWRDQGDDFASIQDKLAIQISRTSAFIM
                     VDDLDHLVKGGRLSNGAAILGNLLSIKPILYFNDQGVIEVYEKVRTEKKATKRLIEII
                     KETTASGQYRVIVIHGNAPEKAEELRQHLLDFGLGSDVSLATFGSVIGTHLGAGSIAL
                     GYIPVI"
     gene            5933..6700
                     /locus_tag="VQ862_001431"
     CDS             5933..6700
                     /locus_tag="VQ862_001431"
                     /EC_number="1.17.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002897644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate reductase"
                     /protein_id="HET3115770.1"
                     /translation="MSIRVIIAGFKGKMGQAACQMVLTDPDLDLVAVLDPFESESEWQ
                     GIPVFKDKADLACFEADVWVDFTTPAVAYENTRFALENGFAPVVGTTGFTSEEIAELK
                     EFSRTQDLGGLIAPNFALGAVLLMQFATQAAKYFPNVEIIELHHDKKKDAPSGTAIKT
                     AELMAEIRESIQQGAADEEELIAGARGADFDGMRIHSVRLPGLVAHQEVIFGNQGEGL
                     TLRHDSYDRISFMTGVNLGIKEVVKRHELVYGLEHLL"
     gene            6712..7896
                     /locus_tag="VQ862_001432"
     CDS             6712..7896
                     /locus_tag="VQ862_001432"
                     /EC_number="2.7.7.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001138849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CCA tRNA nucleotidyltransferase"
                     /protein_id="HET3115771.1"
                     /translation="MPSEFQKALPVLEKIKEAGFEAYFVGGSVRDALLHSPIHDVDIA
                     TSSYPEETKQIFPRTADIGIEHGTVLVLDGDEEYEVTTFRTEDVYVDYRRPSAVSFVR
                     SLEEDLKRRDFTVNAFALDETGEIVDLFHGLEDLEKQVLRAVGVASERFNEDALRIMR
                     GFRFQASLGFALEPETFKAMKTLTPLLENISVERTFVEFDKLLLAPFWRRGLASMIES
                     QAYDYLPDMASSQDKLNRLFDLETDFTFESSEQAWAALLWALEIENAQSFLKSWKTSR
                     QFAKQVQDLLIILALRENGELSKRDCYRFDIDLLLQAENLRQAQGKEVNPQAITEKYQ
                     SLTIHDKKEIQINGGILIKEYGYQPGPDLGEILTEIEFAIVDGELENNREAIHAYLRE
                     KK"
     gene            7893..9764
                     /locus_tag="VQ862_001433"
     CDS             7893..9764
                     /locus_tag="VQ862_001433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001279112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HET3115772.1"
                     /translation="MSDFIVEKLSKSVGDKTVFRDISFIIHDLDRIGLIGVNGTGKTT
                     LLDVLSGVSGFDGDVSPFSAKNDYQIGYLTQDPDFDDRKTVLDTILSSELKEIQLIRE
                     YELIMLDYSEDKQARLERVMAEMDSLQAWEIESQVKTVLSKLGIQDLSTPVGELSGGL
                     RRRVQLAQVLLGNHDLLLLDEPTNHLDIAIIEWLTLFLKNSKKTVLFITHDRYFLDAL
                     STRIFELERAGLTEYQGNYQDYVRLKAEQDERDAALLHKKEQLYKQELVWMRRQPQAR
                     ATKQQARINRFHDLKKEVSGSSAETDLTMNFETSRIGKKVIEFQAVSFAYENKPILQD
                     FNLLVQAKDRIGIVGDNGVGKSTLLNLIAGSLEPTAGQVVIGETVRIAYFSQQIEGLD
                     ESKRVINYLQEVAEEVKTSGGSTTSIAELLEQFLFPRSTHGTLIEKLSGGEKKRLYLL
                     KLLLEKPNVLLLDEPTNDLDIATLTVLENFLQGFAGPVLTVSHDRYFLDKVATKILAF
                     EDGKIRPFFGHYTDYLDEKAFETDMANQVQKAEKEKVVKVREDKKRMTYQEKQEWASI
                     EGDIETLEKRIAAIEEEMQANGSDFGKLATLQKELDEKNEALLEKYERYEYLSEFDS"
     gene            complement(9907..11091)
                     /gene="mntE"
                     /locus_tag="VQ862_001434"
     CDS             complement(9907..11091)
                     /gene="mntE"
                     /locus_tag="VQ862_001434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000813920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDF family manganese efflux transporter MntE"
                     /protein_id="HET3115773.1"
                     /translation="MKQSISNLKLAERGAIISISTYLILSAAKLATGHLLHSSSLVAD
                     GFNNVSDIIGNVALLIGIRMARQPADRDHRFGHWKIEDLASLITSIIMFYVGFDVLRD
                     TIQKILSREETVIDPLGATLGIISAAIMFVVYLYNTRLSKKSNSKALKAAAKDNLSDA
                     VTSLGTAIAILASSFNYPIVDKLVAIIITFFILKTAYDIFIESSFSLSDGFDDRLLED
                     YQKAIMEIPKISKVKSQRGRTYGSNIYLDITLEMNPDLSVFESHEIADQVESMLENRF
                     GVFDTDVHIEPAPIPEDEILDNVYKKLLMREQLIDQGNQLEELLTDDFVYIRQDGEQM
                     DKEAYKTKKELNSAIKDIQITSISQKTKLICYELDGIIHTSIWRRHETWQNIFHQETK
                     KE"
     gene            11395..14091
                     /locus_tag="VQ862_001435"
     CDS             11395..14091
                     /locus_tag="VQ862_001435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HET3115774.1"
                     /translation="MSKEQKRQAFYTQSPEEVLQAVDATEQGLSSSEAEKRLVEFGHN
                     ELEEGEKRSILVKFIEQFKDLMIIILVAAAILSVVTSGGEDIADAIIILAVVIINAAF
                     GVYQEGKAEEAIEALKSMSSPVARVLRDGHMAEIDSKELVPGDIVALEAGDVVPADLR
                     LIEANSLKIEEAALTGESVPVEKDLSVELATDAGIGDRVNMAFQNSNVTYGRGMGVVV
                     NTGMYTEVGHIAGMLQDADETDTPLKQNLNNLSKVLTYAILAIALVTFVVGVFIQGKN
                     PLGELLTSVALAVAAIPEGLPAIVTIVLSLGTQVLAKRHSIVRKLPAVETLGSTEIIA
                     SDKTGTLTMNKMTVEKVFYDAVLHDSADDIELGLEMPLLRSVVLANDTKIDVEGNLIG
                     DPTETAFIQYALDKGYDVKGFLEKYPRVAELPFDSDRKLMSTVHPLPDGRFLVAVKGA
                     PDQLLKRCLLRDKAGDIAPIDEKVTNLIHTNNSEMAHQALRVLAGAYKIIDSIPENLT
                     SEELENDLIFTGLIGMIDPERPEAAEAVRVAKEAGIRPIMITGDHQDTAEAIAKRLGI
                     IDANDTEGHVLTGAELNELSDEEFEKVVGQYSVYARVSPEHKVRIVKAWQKQGKVVAM
                     TGDGVNDAPALKTADIGIGMGITGTEVSKGASDMILADDNFATIIVAVEEGRKVFSNI
                     QKTIQYLLSANTAEVLTIFLSTLFGWDVLQPVHLLWINLVTDTFPAIALGVEPAEPGV
                     MNHKPRGRKASFFSGGVLSSIIYQGVLQAALVMSVYGLAIAYPVHVGDNHAIHADALT
                     MAFATLGLIQLFHAYNVKSVYQSILTVGPFKSKTFNWSILVSFILLMATIVVEPLEGI
                     FHVTKLDLSQWGIVMAGSFSMIIIVEIVKFIQRKLGFDKNAI"
     gene            14104..14895
                     /gene="yghU"
                     /locus_tag="VQ862_001436"
     CDS             14104..14895
                     /gene="yghU"
                     /locus_tag="VQ862_001436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001277405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-dependent disulfide-bond
                     oxidoreductase"
                     /protein_id="HET3115775.1"
                     /translation="MSAYQLPTVWQDEASNQGAFTGLNRPTAGARFEQNLPKGEQAFQ
                     LYSLGTPNGVKVTILLEELLEAGFKEAAYDLYKIAIMDGDQFGSDFVKLNPNSKIPAL
                     LDQSGTENVRVFESAHILLYLAEKFGAFLPSNPVEKVEVLNWLFWQAGAAPFLGGGFG
                     HFFNYAPEKLEYPINRFTMEVKRQLDLLDKELAQKPYIAGNDYTIADIAIWSWYGQLV
                     QGNLYQGSAKFLDASSYQNLVKWAEKIANRPAVKRGLEVTYTEIK"
     gene            15011..15421
                     /locus_tag="VQ862_001437"
     CDS             15011..15421
                     /locus_tag="VQ862_001437"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000412213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HET3115776.1"
                     /translation="MEKKIVKDILFLSQVSQPASQEDLYLARDLQDTLLANRDTCVGL
                     AANMIGVQKRVIIFNLGLVPVVMFNPVLLSFEGSYEAEEGCLSLVGVRSTKRYETIRL
                     AYRDSKWQEQTITLTGFPAQICQHELDHLEGRII"
     gene            15433..17028
                     /locus_tag="VQ862_001438"
     CDS             15433..17028
                     /locus_tag="VQ862_001438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000822862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3115777.1"
                     /translation="MKRIVFELIFIATTWYIFLPPLNLTSWEFLFFLCGHLLVVAILF
                     GFGKGINLVKTVHVRHGKAEAALNLEGFKINRLGKILLASIGGILLLAALVSLVTSSM
                     FQAKNYANVVTVTKKDFTEFPKSDTSKVPILDRSTAEKIGDRYLGSLTDKVSQYVAAD
                     TYTQLTIDGKPYRVTPLEYADPIKWFNNQAKGIGEYIKVDMVTGNADLVDLKTPIKYS
                     DSEYFNRDVKRHLRLKYPTKIFKTPSFEVDDEGNPFYVATVYQKQFGLAVPRPASVII
                     LDATNGETKEYSLSDVPEWVDRIYPAEETIEQINYNGKYKDGFLNAMISKKNVTQTTN
                     GYNYLSIGNDIYLYTGVTSANADESNLGFILENMRTGEITKYSLASATEESARESAEG
                     AVQEKSYKATFPILINLNDKPLYIMGLKDNAGLVKEYALVDAVEYQNVIVATTVEEML
                     SKYANKNDLEIDNATTESINGVVADLKSAVIKGDTVYFFKVDGKIYKVKASVSDDLPY
                     LENGKTFEGQVGKDNYLKTFKLR"
     gene            17095..17259
                     /locus_tag="VQ862_001439"
     CDS             17095..17259
                     /locus_tag="VQ862_001439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000508323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YczI family protein"
                     /protein_id="HET3115778.1"
                     /translation="MGFYLMVASMLLGLLALKIGFSQFKEKKDKFLSILTSLAGTALV
                     LVAVWLGWPK"
     gene            17338..18066
                     /gene="yaaA"
                     /locus_tag="VQ862_001440"
     CDS             17338..18066
                     /gene="yaaA"
                     /locus_tag="VQ862_001440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000697769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxide stress protein YaaA"
                     /protein_id="HET3115779.1"
                     /translation="MKILIPTAKEMNTDLPSIEAIPLKPESQAVLDALALYSASQLES
                     FYKVSAEKAAEEFQNIQALKRQTAQHYPALKLFDGLMYRNIKRDKLTEAEQDYLENHV
                     FITSALYGVVPVLSPMAPHRLDFLMKLKVAGKTLKSHWKAAYDETLKKEEVIFSLLSS
                     EFETVFSKEIRAKMVTLKFMEDRGGQLKIHSTISKKARGAFLTALIENQVQTVGEARR
                     LNFAGFVYREDLSQPQGLVFVKEV"
     gene            complement(18343..18891)
                     /locus_tag="VQ862_001441"
     CDS             complement(18343..18891)
                     /locus_tag="VQ862_001441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000039625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HET3115780.1"
                     /translation="MSKKVLFIVGSLRQGSFNHQMALEAEKALAGKAEVSYLDYSALP
                     LFSQDLEVPTHPAVAAAREAVLVADAIWIFSPVYNFSIPGTVKNLLDWLSRALDLSDT
                     RGVSALQDKFVTVSSVANAGHDQLFAIYKDLLPFIRTQGVGDFTAARVNDSAWADGKL
                     VLEETVLNSLEKQAQDLVEAIK"
BASE COUNT         5516 a         3638 c         4397 g         5542 t
ORIGIN      
        1 taaatagaaa ggaaactttc taaattgttc tttcaccgca ggctcaggct tgcggttttt
       61 ttgttttaaa aaaggggcaa aaaaggggca aaagtgtcgt aaacctctgt aaaatgatgt
      121 aaaaacattt atttaaaagc tcaaaatata gctgttttaa aaggtattgt aagatatagt
      181 aaaacgatgt aaaggtattt ttaaatgcgg atgaattata aaaccacgaa tcctatgtga
      241 ctcgtggttc ttttttataa actagtagag tgttttggtt gtactttttg ttcagggtca
      301 atgtagttga tagcgttgtt gacagcagtt ggagcttctc cgaggcctgt cgcaatcaga
      361 tcaatttttc cgtcatagta gcagcagtca ccgatagcat agatacctgc ttggctggat
      421 tcctgtttgc tgttgacgat aatcttgtga cggttgaggt cgagccccca gtttttaagg
      481 ttaccgacag aagatttgaa accatagttg acaaagaggt ggtctaggtc aatggtttca
      541 gtttcatcag atttgacttt tgtgatttca agtttatcaa gtgtttttcc atttccaagg
      601 agttggctag gggcgaatgg tgtcttgatg gttacagatg atttttgcaa ggcttgaaca
      661 ctgtgttcca aggcacggaa attatctctg cggtgaacaa gggtagttgg tgcgattttt
      721 tcaaaagcca aagcccaatc cacagccgag tctcccccac caagaatcgt cactttctta
      781 ccagcgtatt gctgaatgtt agaaacgtgg tagtggatat tttcatagcc ctcaacccct
      841 tcaagttcca gcggacgtgg tttgaaggca ccgccaccca tagcgatgat gactgtttta
      901 gtcaagtgac ttcctttaga agttgtgatg gcaaattctt cttcttgttt gtcaatctca
      961 agaaccgttt cattgagatg aataggggta tcaaatccat ttagctgttc aatcaagcgg
     1021 ttagtcaact cttctccagt caggtttggg aagcctggta cgtctaggat ttccttttca
     1081 gggtagagaa tagcaggttg tccacctagc tggggaagag agtcgatgat ttgaaccttg
     1141 gcttggcgta ggtgggcata aaaggctgca aaaagcccga caggaccacc acccacaatg
     1201 gtaatatcat agagttgaga catagtttct cctttgtttt ttctagtcag tttattttat
     1261 catatttttg ttcaatgtaa actggactag gatagggaaa aaaatgccag aaaatggtat
     1321 aataggacga aagtgttttg atagggagga tatcagggat gaattttcaa caattatcca
     1381 atctgcaata ttggaccagt ttgtttgcaa gtccatggac gatagctatc aatctgattg
     1441 atattttgat tgttgcttat attttatacc attttacaaa agctattgca ggaaccaaga
     1501 ttatgatttt ggtacgtgga gttttggtgt ttattttagc tcaaatcctt gcaaatatga
     1561 ttggtttgac tacgatttct tggttaatca atcaaattat tacttatggg gttattgcgg
     1621 cggttgttat cttctctcca gagattcgga ctggtttgga acgtttggga agagcgacag
     1681 atttcttttc caatgcccct attagtgctg aggaacagat gattcgtgcc tttgttaagt
     1741 ctgttgaata catgagtcct cgtaaaatcg gggccttggt tgctattcag cgtgtacgta
     1801 ccttgcagga gtatatttcg acaggaattc ccttggatgc taagatttct gcagaacttc
     1861 tcattaacat ttttattccc aacactcccc tacatgatgg tgcggtgatt atcaaagaag
     1921 aacgtatcgc tgtgacgtct gcctatctgc ccttgacaaa aaacacaggg atttccaagg
     1981 aatttgggac cagacaccgg gcggctatcg gtttatcaga agtctcagat gccttgactt
     2041 ttgttgtatc agaggaaacg ggaggaattt cgataaccta taatggaagg tttaagcaca
     2101 acctaacact tgatgaattt gaaacagaat tacgtgaaat cttacttcca aaagaggaag
     2161 tgggtcttag ttttaaagaa cgattgctag gaggatggaa acatgaaaaa aaatagttta
     2221 tatatcatat cctcactctt ttttgcttgt gtcttatttg tctatgctac ggcgacgaat
     2281 tttcaaaaca gtaccagtgc taggcaggta aaaacggaaa cctatactaa tacagtaaca
     2341 aatgtcccta ttgacatacg ctataatagt gataagtatt ttattagcgg ttttgcttca
     2401 gaagtatcag tggtcttgac tggtgcaaat cgcctatcgc tagctagtga aatgcaagaa
     2461 agtacacgta aattcaaggt tactgctgac ctaacagatg ccggtgttgg aacgattgaa
     2521 gttcctttga gcattgaaga tttacccaat gggctgaccg ctgtggcgac tccgcaaaaa
     2581 attacagtca agattggtaa gaaggctcag aaggataagg taaagattgt accagagatt
     2641 gaccctagtc aaattgatag tcgggtacaa attgaaaatg tcatggtgtc agataaagaa
     2701 gtgtctatta cgagtgacca agagacattg gatagaattg ataagattat cgctgtcttg
     2761 ccaactagcg aacgcataac aggtaattac agtggttcag tacctttgca ggcaatcgac
     2821 cgcaatggtg ttgtcttacc ggcagttatc actccgtttg atacaataat gaaggtgact
     2881 acaaaaccag tagcaccaag ttcaagcaca tcaaattcaa gtacaagcag ttcatcggag
     2941 acatcttcgt caacgaaagc aactagttca aaaacgaatt aaaaatagaa aaggatttta
     3001 taacaatggg taaatatttt gggactgatg gagtccgtgg agaagctaac ctagaactaa
     3061 caccagaatt agcctttaaa ctaggacgtt ttggaggcta tgttcttagt caacatgaaa
     3121 cggaagcgcc gaaagtcttt gtaggacgtg acacacgtat ttcaggggaa atgctggaat
     3181 cggccttggt ggcaggtctc ctttcagtag ggattcacgt atacaaactt ggtgtccttg
     3241 caacaccagc agtagcttac ttggttgaaa ctgaaggagc aagtgccggt gtcatgattt
     3301 ctgctagcca caacccagcc cttgataacg gaatcaagtt ctttggcggt gatggcttca
     3361 aactagatga tgaaaaagaa gcagaaattg aagccttgct agatgctgag gaagacactc
     3421 ttcctcgtcc aagtgcagaa ggcttaggaa tcttggtaga ttatccagaa ggcttgcgta
     3481 agtatgaagg ataccttgtt tcaactggaa ctcctcttga tggaatgaag gttgccttgg
     3541 atacagctaa tggagcagct tctaccagtg cccgtcaaat ctttgcagac cttggtgccc
     3601 aattgacggt tatcggggaa acaccagacg gtcttaacat caaccttaat gttggttcaa
     3661 cacatccaga agcccttcaa gaagtggtca aagaaagtgg gtcagctatt ggtttggcct
     3721 ttgatggaga cagtgaccgc ttgattgctg ttgatgagaa tggtgacatc gtcgatggtg
     3781 acaagattat gtacatcatc ggaaaatacc tttctgaaaa aggacaattg gctcaaaata
     3841 caattgtgac aactgttatg tctaaccttg gtttccacaa ggccttgaat cgcgaaggta
     3901 ttaacaaggc agttactgca gttggtgacc gctacgttgt tgaagaaatg agaaaatcag
     3961 gctacaacct tggtggtgaa cagtctggtc acgttatctt gatggattac aataccacag
     4021 gtgatggtca attatcagca gttcaattga ctaaaatcat gaaggaaact ggtaagagct
     4081 tatcagagtt ggcggcagaa gtaacgattt atccacaaaa attagttaat atccgagtgg
     4141 aaaacgtcat gaaggaaaag gccatggaag tgccagctat caaggccatc atcgagaaga
     4201 tggaagaaga aatggcgggg aacggccgta tccttgttcg tccaagtgga acagagcccc
     4261 tcttgcgtgt tatggcagaa gcgcctacaa cagaagaagt agactactat gttgatacca
     4321 tcacagatgt agttcgtgct gaaattggga ttgattaaat cctagaaaac tagatgaaaa
     4381 taaaaaatta tggtacaata gcttataata ttgtagccga tggagaaaga catgaatctt
     4441 aaacgtgaac aagaatttgt tagtcagtat cattttgatg cgcgtaattt tgaatgggaa
     4501 aatgaaaatg gagctcctga aaccaaggtg gatgtgaatt tccaattgct ccaacatgac
     4561 caagaaaatc aagtgacttc cttgattgtc atcttgagct ttatgattgt atttgataag
     4621 tttgtcatta gtggaacaat ctcacaagta aaccatatcg atggccgtat tgtcaatgaa
     4681 ccaaatgaat tgaaccaaga agaggtggaa accttggctc gtccatgttt gaacatgctc
     4741 aatcgtttga cttacgaagt gactgaaatt gcattagact taccaggaat taatttggag
     4801 ttctaatatg aaattagctg ttttcacaga ttcctctgct tatctcagtg cagagacctt
     4861 gcaaagagaa gacttgtttg tcttggatat tcctgtcaat attgatggtg aggaatatgt
     4921 cgaaggcatc aatctgtctg ctgaggaatt ttaccaaaaa atggctcagg cttctgaatt
     4981 gcctaagacc agtcaaccaa gtattgccaa gttagatgaa atcttaactt cgctcaaaga
     5041 acaaggctat acacatgcct tggggctttt cctatcttct ggaatttcag gtttttacca
     5101 aaatatccag tatatggtcg atgactatga gggcttaacc attgctttcc cagacacttt
     5161 gattacaagt gctcccctag gcatcatggt tgaaagcgtc tttaattggc gtgatcaggg
     5221 cgatgatttt gccagcattc aggataagct agccattcaa atcagccgta cgtcagcctt
     5281 tatcatggta gatgacttgg atcatttggt aaaaggtgga cgtctttcaa atggggctgc
     5341 cattttgggc aatttgctta gcattaagcc aatcctttat tttaacgatc aaggtgtgat
     5401 tgaagtttac gaaaaagttc gtactgaaaa gaaggccacc aagcgcttaa ttgaaattat
     5461 caaggaaaca acggcttcag gtcaataccg ggtcattgtc attcatggga atgctcctga
     5521 aaaggctgaa gaattgcgtc agcatttgct tgattttggc ttgggttcgg atgtttcact
     5581 tgctacattt ggtagtgtca ttggaacgca cctaggagca ggaagtattg ctctgggtta
     5641 tattccagtg atttagttgg cgcttctagg ctagttaaga tgccttgtat cttagcaatt
     5701 gaacacggac tacctgcttc ttgaaaaaag atgcctgtct tgcctttcgt ggaaagtcag
     5761 tgccattccc tatttttcag gggcagctaa ggtcctttgt atcttgataa ttgaacacgc
     5821 ctggaaccct gtgtgaaaaa gatagttctt ccaagaagta gacacttctt gattggaatt
     5881 cctattttca ctttgtgttc ttacggactt tgtatcttag acaggagtag agatgagtat
     5941 tcgagtaatt attgccggtt ttaagggaaa gatgggccag gctgcttgtc agatggtatt
     6001 gactgatcca gacttggact tggtagcagt tttggatcct tttgagtctg agtcagaatg
     6061 gcagggtatt cctgttttca aggataaggc tgatttagct tgttttgaag cggatgtctg
     6121 ggtagatttt actactccag ctgttgccta cgaaaataca cgttttgctc ttgaaaatgg
     6181 ctttgctcca gtagttggaa cgactggttt cacgagtgaa gaaattgcag agctaaaaga
     6241 attttctcgt acccaagact tgggtggcct gattgcccct aactttgcct tgggtgctgt
     6301 cttactcatg caatttgcga cgcaggctgc caaatatttc ccaaatgtgg agattattga
     6361 gctccatcat gacaagaaaa aggatgctcc gagtggaaca gccattaaaa cagctgagtt
     6421 gatggcagag attcgagagt caattcagca aggtgcagca gatgaggaag agctgattgc
     6481 tggtgctcgt ggtgctgact ttgatggtat gcgcatccac tcagttcgtt tgccaggttt
     6541 ggtagcccat caggaagtca tctttggcaa tcaaggagaa ggattgaccc tccgtcatga
     6601 ctcctatgat cgcatctcct tcatgacagg agtcaatttg ggaattaaag aagttgtcaa
     6661 gcgtcatgag cttgtctatg gattagaaca cttattatga gattaatgca aatgccttct
     6721 gaatttcaga aggctttacc agtattagaa aaaattaaag aagcaggctt tgaggcttat
     6781 tttgttgggg gctctgttcg agatgccctt ctccatagcc ctatccacga tgtggatatt
     6841 gcgacgtctt cttatccaga agagaccaag cagatttttc cgcgaacagc cgatatcgga
     6901 atcgagcatg gaaccgtctt ggtcttagat ggggatgagg agtatgaggt aacaaccttt
     6961 cggacagagg atgtctatgt ggactatcgc agacccagtg cggtttcctt tgtgcgctcg
     7021 ctagaagaag acctcaaacg ccgtgatttc acagtcaacg cctttgcctt ggatgagaca
     7081 ggagaaatcg ttgacttgtt ccatggttta gaagatttgg aaaagcaagt cttgcgagca
     7141 gttggagtgg ctagtgagcg tttcaacgaa gatgctttac ggattatgcg tggtttccgt
     7201 tttcaggcta gtcttggttt tgcacttgaa ccagaaacat ttaaagctat gaagaccttg
     7261 acgccgcttt tggagaacat ttctgtagag cgtaccttcg tcgagtttga taaactcttg
     7321 ctggctccat tttggagaag ggggttggct tccatgattg agagtcaagc ttatgactat
     7381 ctccctgata tggcatctag ccaggacaag ctcaacagac tgtttgattt ggagactgat
     7441 tttacttttg aatcctctga acaagcctgg gcggctttac tatgggcttt ggagattgaa
     7501 aatgcgcagt catttttgaa atcttggaag acctcacgcc agtttgccaa gcaagttcag
     7561 gatttgctga ttattttggc tctgcgtgaa aatggagaat tgagcaagcg agattgttat
     7621 cgctttgaca tagatttgct tttacaggct gaaaatcttc gtcaagctca aggaaaagaa
     7681 gtcaacccac aagccatcac agaaaaatac caaagcttga ctatccatga caagaaagag
     7741 attcagatta atggcggtat tttgatcaag gaatatggct atcagccagg cccagacttg
     7801 ggagagattt taacagagat tgagtttgcc attgtcgatg gagaattgga gaataatcgt
     7861 gaagccatcc atgcttacct gagggagaaa aaatgagtga ttttatcgtt gaaaaactaa
     7921 gtaaatctgt tggtgacaag accgttttta gggatatttc ctttattatc catgacttag
     7981 acagaattgg tttaatcggt gtcaatggga ctggcaagac cacccttttg gacgtccttt
     8041 ctggtgtttc tggctttgat ggggatgtca gtcctttttc agctaaaaat gattaccaga
     8101 ttggttactt gactcaggat cctgattttg atgatagaaa gacagttttg gatacgattc
     8161 tatctagtga actcaaggaa atccagctca ttcgtgagta tgaattgatt atgctcgact
     8221 atagcgagga caagcaggcg cgtttggaac gtgtcatggc agagatggac tctctccaag
     8281 cttgggaaat cgagagtcag gtcaagaccg ttcttagcaa attgggcatt caagacttat
     8341 ctactcctgt tggggaattg tcaggtggtc tgagaagacg ggtacagttg gcacaagtct
     8401 tacttggcaa ccacgacctc ttgcttttgg atgagccgac caaccatctg gatattgcga
     8461 ttattgagtg gctgaccctc tttttgaaaa attctaagaa gaccgtcctt tttatcactc
     8521 acgatcgtta tttcttagac gctttgtcaa cacggatttt cgagttggag cgagcaggct
     8581 tgacagaata tcagggcaat taccaggact atgttcgcct taaggcagaa caggacgagc
     8641 gcgatgcagc tctacttcat aaaaaagaac aactctacaa acaagaactg gtctggatgc
     8701 gcagacaacc gcaggcacgt gcgaccaagc aacaagctcg tatcaatcgt ttccatgatc
     8761 tgaaaaagga agtttcaggc agtagtgctg agacagactt gactatgaac tttgaaacca
     8821 gtcggattgg gaagaaagtc atcgagtttc aggctgtttc ctttgcctat gaaaataagc
     8881 ccattttgca agattttaat ctcttagttc aggctaaaga ccgtattgga attgttgggg
     8941 acaatggtgt tggaaaatca accctactta acctgattgc aggaagtctt gagccgacag
     9001 caggacaagt tgtgattggg gaaactgttc gcatcgccta tttctctcaa caaattgagg
     9061 gtttggatga aagcaagcgt gtgatcaatt acctgcagga agtggcagag gaggtcaaga
     9121 ccagtggtgg ttctacgact tccatcgctg agttgctgga gcaattcctc ttcccacgtt
     9181 cgacgcatgg gaccttgatt gagaaattgt cagggggtga gaaaaaacgt ctttatctcc
     9241 tcaaactgct tttggaaaaa ccaaatgttc ttcttttaga cgagccaacc aatgacctag
     9301 atattgcaac tttgacagtc ttagagaatt tcttgcaagg ttttgcaggt cccgttttaa
     9361 cagtcagtca cgaccgctat ttcttggata aggtagcgac caagattctc gcttttgagg
     9421 atggcaagat tcgtcctttc tttggtcatt acaccgacta tcttgatgaa aaagcttttg
     9481 aaacagatat ggccaatcaa gtgcaaaagg ccgaaaagga aaaagtggtc aaggttcgag
     9541 aagacaagaa acgcatgacc taccaagaaa agcaggagtg ggcaagtatt gaaggtgata
     9601 ttgaaacctt ggaaaaacgt atcgctgcta ttgaagagga aatgcaggct aacggctctg
     9661 actttggtaa gctggctact ctccaaaaag aattggatga gaaaaatgaa gcactccttg
     9721 aaaaatacga acgctatgag tatctcagtg aatttgatag ttaatactat tcgaaaatca
     9781 aagtgtaaac tatgtcggct tcacattgcc gactcaagta cagcctgtgg ccggcttcct
     9841 agtttgcact ttgattttta ttgagtataa aagaatagaa aaatcccatc tcatgaacgg
     9901 atttctctat tcttttttgg tttcttgatg aaagatattt tgccaggttt cgtggcgacg
     9961 ccagatactg gtatggatga taccatctaa ctcatagcag atgagtttgg ttttttgact
    10021 gatggaagta atttgaatgt ccttgatagc agaatttaac tcttttttgg tcttataagc
    10081 ctctttatcc atctgctctc catcttggcg aatatagaca aaatcatcag tcaagagttc
    10141 ttctagttgg tttccttggt caatcaattg ttcacgcata agcaattttt tatagacatt
    10201 gtctaaaatt tcatcctcag ggataggtgc tggttcgata tggacatcgg tatcaaagac
    10261 gccaaaacga ttctccagca tagactcgac ctgatccgcg atttcatggc tttcaaaaac
    10321 agacaagtca ggattcatct ctagtgtaat atccaggtag atgttgctac cgtaggtgcg
    10381 acctctttgc gatttgacct tgctgatttt gggaatttcc atgatagcct tttggtagtc
    10441 ctcgagcagg cggtcgtcaa agccatctga aagactaaag gaagactcga tgaagatatc
    10501 ataggcagtc ttcaagataa agaaagtgat gatgatagca accagtttat ccacaatcgg
    10561 ataattgaaa ctactagcta ggatggcaat ggcggttcca agtgaggtaa cagcgtcaga
    10621 aagattgtcc ttagcagctg ctttcagcgc cttggagttg gatttcttac tgaggcgagt
    10681 attgtagaga tagaccacaa acataatcgc tgcagaaatg attcctagag ttgcaccaag
    10741 aggatcaatg accgtttctt cccgactgag aatcttttga atggtatctc ttagaacatc
    10801 gaaaccgaca tagaacatga tgatagaagt gatcaagctt gccaaatctt caatcttcca
    10861 atgaccaaaa cggtggtcac ggtctgcagg ctggcgcgcc atccgaatcc cgattaagag
    10921 ggccacattt ccaatgatgt ccgatacgtt attaaaacca tcggccacca aactggatga
    10981 atgaaggaga tgaccagttg ctaatttggc tgcagacaag atcaaatagg tcgaaatact
    11041 gataatggct ccacgctcag ctaacttgag atttgagata gattgcttca ttcaacttcc
    11101 tttctagtca catagcattc taccattata ctggttttca aggaaaaatt caaataaggc
    11161 agtttttact ctttgaaaac tccccaaaat ttggtataat agtactactc aagggagtag
    11221 ctggcagaaa cctgtgatag tgtcgtcatt ccgaatttta tgctgaaaag tatgctttcc
    11281 ggccctatct taaacagcga gacttgttat gattaacagg tctctttttg tttgtcgtga
    11341 aaagatatga cagaaagaga gtctgttttg cacacaatgt caaggaggag acacatgtca
    11401 aaagaacaaa aacgccaagc gttttatact cagagccctg aagaggtctt gcaggctgtg
    11461 gatgcgaccg agcaaggttt gtcgtcaagt gaggcggaaa agcgccttgt cgaatttggg
    11521 cacaatgaac tcgaagaagg cgagaaacga tcaatcttgg tcaaattcat cgagcaattt
    11581 aaggatttga tgattatcat cctagttgcg gcagcaatct tgtcagtcgt gacttctggt
    11641 ggggaagata tcgcagatgc cattatcatc ctagctgtgg ttatcatcaa cgctgccttt
    11701 ggtgtttacc aagaaggaaa agctgaagaa gctattgaag ccctcaaatc catgtctagt
    11761 ccagttgccc gcgttcttcg tgatggacac atggcagaga ttgactctaa agaattggta
    11821 ccaggcgata tcgttgccct tgaagcaggt gacgtggtac cagcggacct acgtttgata
    11881 gaagccaact ctcttaaaat tgaagaagca gccttgacag gtgaatctgt accagtcgaa
    11941 aaagacttgt cagtcgagct tgcgacagat gctggtattg gtgaccgtgt caacatggcc
    12001 ttccaaaact caaacgtaac ctatggtcgt gggatgggtg ttgttgtcaa tacaggtatg
    12061 tacactgaag ttggtcatat tgctggtatg cttcaagatg cggatgagac tgatacacca
    12121 ctcaaacaaa acttgaacaa cctttctaag gtcttgacct atgctatctt ggccattgcc
    12181 cttgttactt ttgtagtggg tgtcttcatt caagggaaaa atccacttgg tgagttgttg
    12241 acttctgttg cccttgccgt tgcagccatt ccagaaggac ttcctgctat cgttaccatc
    12301 gttctttctc ttggtactca agttttggcc aaacgacatt ccatcgttcg taagttgcca
    12361 gcagttgaaa cacttggttc aactgaaatc atcgcttctg ataagactgg tacgctgact
    12421 atgaacaaga tgacagtcga aaaagtcttc tacgatgcgg ttctacatga ctcagctgat
    12481 gatattgaac taggtcttga aatgccacta cttcgttcag ttgtcttggc caatgatacg
    12541 aaaatcgatg tggaaggtaa cttgattggt gacccaaccg aaacagcctt tatccaatat
    12601 gccttggaca agggctatga tgtcaaaggt ttcttagaga aatatcctcg tgtagctgaa
    12661 ttgccatttg actctgaccg taagctcatg tcaacagttc acccattgcc agatggtcgt
    12721 ttccttgtag cagtcaaggg tgcgccagac caactcttaa aacgttgtct tcttcgtgat
    12781 aaggctgggg atattgctcc gattgatgag aaggttacaa atctcattca tacaaacaat
    12841 tctgaaatgg ctcatcaagc cttgcgtgtc cttgcaggtg cttataagat tatcgatagt
    12901 attccagaaa atctcacttc tgaagagctt gaaaatgatt taatttttac tggtttgatt
    12961 gggatgattg accctgaacg tcctgaagcc gctgaggctg ttcgtgtggc taaggaagcg
    13021 ggaatccgtc caattatgat tacaggtgac caccaagaca cagcggaagc cattgccaaa
    13081 cgtttgggaa tcattgacgc aaacgataca gaaggtcacg ttttaactgg tgctgaactc
    13141 aatgaactgt cagatgaaga atttgaaaaa gtcgttggtc aatactctgt ttatgcccgt
    13201 gtgtctccag aacacaaggt tcgtatcgtc aaggcttggc aaaaacaagg taaagtcgtt
    13261 gccatgacag gtgacggtgt caatgacgcg ccagctctga aaacagccga tatcggtatc
    13321 ggtatgggaa tcactggtac agaggtttct aagggggctt ctgatatgat tcttgcagat
    13381 gataactttg cgactattat cgtcgcagtg gaagaaggac gtaaggtctt ctcaaacatt
    13441 caaaagacta ttcagtacct actttctgct aatactgctg aagtattaac catcttccta
    13501 tcaaccttgt ttggttggga tgtcttgcag ccggttcatc ttttgtggat caacttggta
    13561 acggatacct tcccagctat cgctcttggt gttgaacctg cggagcctgg tgtcatgaat
    13621 cataaaccac gtggacgcaa ggcaagcttc ttctcaggtg gtgttttgag ttctatcatt
    13681 tatcaaggtg tactccaagc agctcttgtt atgagtgttt atggccttgc gattgcttac
    13741 ccagttcatg tgggtgacaa tcatgctatt catgcagatg ccctaacgat ggcctttgca
    13801 acccttggtt tgattcagct cttccatgcc tacaatgtca agtctgtcta ccaatccatc
    13861 ttgacagttg gcccattcaa gtctaagacc tttaactggt ccatcttggt atcttttatc
    13921 cttctcatgg caacaatcgt tgtagaaccg cttgaaggaa tcttccacgt aaccaaacta
    13981 gacttgtcac aatggggaat tgttatggct ggaagcttct caatgattat catcgtcgaa
    14041 atcgttaagt ttattcaacg caaactcggt tttgacaaga atgcgattta agggaggttt
    14101 cggatgtcag catatcaatt accgaccgta tggcaggatg aagctagtaa tcaaggagct
    14161 tttacggggc taaacagacc aacagcaggt gcccgtttcg aacaaaactt gccaaaagga
    14221 gaacaagctt ttcagcttta ttcactggga acaccaaatg gtgtgaaggt tactatctta
    14281 ttggaagaat tactagaagc tggttttaag gaagcggctt acgacttgta taagattgct
    14341 atcatggatg gggatcaatt cggctcagac tttgtgaagc tcaatccaaa ttccaagatt
    14401 ccagccttat tggaccagtc aggtactgaa aacgtaagag tctttgagtc tgctcatatt
    14461 cttctttacc ttgctgagaa atttggagcc tttttaccaa gtaatcctgt ggaaaaggta
    14521 gaagttttga attggctatt ctggcaagca ggtgcagcac cttttctagg tgggggattt
    14581 ggacatttct tcaattatgc tcctgaaaaa ttggaatatc ctattaaccg ttttacgatg
    14641 gaagtgaaac gccagttgga tttattggat aaggaattgg ctcagaaacc ttatattgca
    14701 ggcaatgact atacgattgc agatattgct atctggtctt ggtatggaca gttagttcaa
    14761 ggaaatcttt accaaggttc tgcaaaattc ttggatgcct caagttatca aaatctagta
    14821 aaatgggcag aaaaaattgc caatcgtcca gctgttaagc gtggattgga agtaacttat
    14881 acagaaatta aatagcaaaa aagtcatctt cggatggctt tttgctacag ttgagggaaa
    14941 gggtttgcag ttatcggctt ttgtgctata attgctataa tatagtaaaa agcaagagga
    15001 gtgtgaggaa gtggaaaaga aaattgtgaa ggatatctta tttttatctc aagtgtctca
    15061 gccggcaagt caggaggacc tttatcttgc cagagatttg caggatacac tcttagcaaa
    15121 tcgtgatacc tgtgttggtc tagctgccaa tatgattggg gtgcagaagc gcgtgattat
    15181 ctttaatctt ggcttggttc ctgtggtcat gtttaaccca gtgcttctgt cctttgaagg
    15241 atcctatgag gcagaagaag gctgtttgtc cttggtaggt gtgagatcaa ctaagcgtta
    15301 tgaaaccata aggcttgcct atcgtgacag caagtggcag gaacagacca ttaccttgac
    15361 aggcttccca gctcagattt gccagcatga gctggatcac ttggaaggac gaatcattta
    15421 ggaggaaagc aaatgaaacg aatagtcttt gaacttattt ttatcgcaac gacctggtat
    15481 atctttttac cgccccttaa cctgaccagc tgggaatttc tcttcttcct ctgtgggcat
    15541 ttgttagttg tggcaatatt atttggcttt ggcaagggga taaaccttgt caaaacggtt
    15601 catgtgcgcc acggtaaggc ggaagctgcc ttaaatcttg agggtttcaa aatcaatcgg
    15661 ttagggaaaa ttctgttagc ttcgattgga ggaattcttc tcttggcagc tttggtttcc
    15721 ttggtaactt ccagcatgtt tcaggctaaa aattatgcca atgtagtcac ggttacgaaa
    15781 aaagacttta ctgaatttcc taagagtgac accagtaagg ttcctatcct agatagaagt
    15841 actgctgaaa aaattggaga ccgctacttg ggttccctaa ccgataaggt gtcgcaatac
    15901 gtagcggcag atacctatac ccaattgaca attgatggga aaccttatcg ggtcacacca
    15961 ctagaatatg cagaccctat caaatggttt aacaatcaag ccaagggaat cggtgagtat
    16021 attaaggtgg acatggtaac tggaaatgcg gatttggtgg acttgaagac accaatcaag
    16081 tattcagact cggagtattt taaccgtgat gtcaaacgtc acctgcgctt gaagtacccg
    16141 accaaaatct ttaaaactcc atcttttgag gtggacgatg agggcaatcc tttctatgta
    16201 gcaacggttt accaaaagca atttggactt gctgttcctc gtcctgcttc agtcattatc
    16261 ttggatgcta caaatggaga aaccaaggaa tacagcttat cagatgttcc agaatgggtg
    16321 gacaggatct atccagcaga ggaaaccatt gagcaaatca actacaacgg caagtacaag
    16381 gacggtttct tgaatgccat gatttccaag aaaaacgtga cccagactac caatggctat
    16441 aattacttgt ctatcggtaa tgacatctat ctctacacag gtgtgacgtc ggctaatgcg
    16501 gatgagagta atcttggttt catccttgaa aatatgcgaa caggagaaat cactaagtat
    16561 agcttggctt ctgcgacaga agaatcagcc cgtgaatcag cagaaggtgc tgttcaggag
    16621 aaatcctaca aagcaacctt cccaatcctc atcaacctca atgacaagcc tctctacatc
    16681 atgggcttga aggacaatgc tggcttggtc aaagagtacg ccctggtaga cgcagtcgag
    16741 taccaaaatg ttatcgttgc tactacagtg gaagagatgc tcagcaagta tgccaataaa
    16801 aacgaccttg aaattgacaa tgcaacgaca gaaagcatca atggagtagt agcagacctc
    16861 aaatcagctg ttatcaaggg agacactgtc tacttcttta aagttgatgg caagatatac
    16921 aaggtcaagg cttcagtatc cgatgacctt ccttaccttg aaaatggtaa aaccttcgaa
    16981 ggtcaagtag gaaaagacaa ttatctcaag acctttaagc tacggtaaaa ataggttttt
    17041 ttcagaaagt atatgttata ataaggtaaa ttaagcctaa tggaggacaa agaaatgggt
    17101 ttttatttga tggttgcttc aatgctactc ggactgctcg ctttgaagat aggtttttct
    17161 cagttcaagg agaaaaaaga taaattctta tctatcttaa caagtttagc tggcacagcc
    17221 cttgttctcg tggctgtctg gttaggatgg cccaaataaa tagaaaaacc tcggtcaaac
    17281 cgaggttttt caaatgaatt tcttggttgt ggctaaaaaa tatgctacac tatcaatatg
    17341 aaaattttaa tcccaacagc aaaagaaatg aacacagact tgccaagtat cgaggcaatt
    17401 cctttaaaac cagaaagtca ggccgtgctt gatgccttgg ctctctattc tgccagtcaa
    17461 ttggagagtt tctacaaggt atcagctgag aaagcggcgg aagaatttca aaatatccaa
    17521 gctttgaaaa ggcaaactgc tcaacactat ccagccttga aactttttga tgggcttatg
    17581 taccgcaaca ttaagagaga taagctgacc gaggcggaac aagattatct tgaaaatcat
    17641 gttttcatta cctcggcttt gtacggtgtt gttccagtct tgtcacccat ggctcctcac
    17701 cgtttggatt ttttgatgaa attaaaagtc gctggtaaga ctttgaagag ccattggaag
    17761 gcagcctatg atgaaactct gaagaaggaa gaagtgattt tctctctctt gtcatcagag
    17821 tttgagactg tattttctaa ggaaatcaga gcaaagatgg tgaccttaaa attcatggag
    17881 gatagaggcg gtcagctgaa gattcactca actatctcca agaaagcgcg cggggccttt
    17941 ctaacagctt taatagaaaa tcaagtacaa actgtggggg aagcacgtcg cttgaacttt
    18001 gctggatttg tttaccgaga agatttgtca caaccacagg gattggtttt tgtaaaggaa
    18061 gtatagaaat cagatatttt gtatttggca atatgtatca tcagctattt tagtttataa
    18121 atgagaaaaa agcgaacaag ctagtcttct gagtgtcaga aaagtagtct tgttcgcttt
    18181 tattatgtta tactcttcga aaatctcttc aagccacgtc agtgtcgcct taccgtatat
    18241 atgttactga cttcgtcagt tctatctaca acctcaaagc agtgctttga gtagcttgcg
    18301 gctagcttcc tagtttgctt tttgattttt attgagtgtt agttacttga tagcttcgac
    18361 caagtcttga gcttgttttt caagtgagtt taggactgtt tcttcaagaa ccaattttcc
    18421 gtctgcccag gcagagtcat taacacgtgc agcagtgaaa tcaccaacgc cttgtgtacg
    18481 gataaatggc aagaggtctt tgtagatagc gaaaagttga tcgtgccctg cattggctac
    18541 agatgatact gtgacaaact tgtcttgaag ggcagaaacg ccacgtgtat cagacaagtc
    18601 aagggcacga gatagccagt caagcaagtt tttcactgta ccagggatag agaagttgta
    18661 gactggagag aaaatccaga tagcatccgc aacgagaact gcttcacgag cagcagctac
    18721 agctggatgt gttggaactt ccaaatcttg gctgaagaga ggaagggctg aataatcaag
    18781 gtagctaact tccgctttac cagcaagtgc tttctcagct tcgagcgcca tttggtggtt
    18841 gaaagaacct tgacgtagtg atccgacgat aaataatact tttttagaca tgatgtgtct
    18901 cctttttctt aaaatttcga gaactctctc gttgttataa aatatattac aacaaaacaa
    18961 aagaacttgc aagaaatttg ctcagagttt atttgaaaat tgtaaaattt cggaaactct
    19021 agtcatttgt gactgaaaaa gtaagaactg tttcactttc aaaatcggtt ttgtttgaag
    19081 ggagaaatag aat
//
LOCUS       DAVBOD010000039        18415 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 640-05
            SAMEA1012484-rid20186543.denovo.039, whole genome shotgun sequence.
ACCESSION   DAVBOD010000039 DAVBOD010000000
VERSION     DAVBOD010000039.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012484
            Sequence Read Archive: ERR059358
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 18415)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18415)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979948.1
            Genome Coverage       :: 595x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:03:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,266
            CDSs (total)                      :: 2,219
            Genes (coding)                    :: 2,091
            CDSs (with protein)               :: 2,091
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 71 of 128
            Pseudo Genes (incomplete)         :: 50 of 128
            Pseudo Genes (internal stop)      :: 33 of 128
            Pseudo Genes (multiple problems)  :: 22 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18415
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012484-rid20186543.denovo.039"
                     /strain="NIG 640-05"
                     /db_xref="taxon:1313"
     gene            3..75
                     /locus_tag="VQ862_001442"
     tRNA            3..75
                     /locus_tag="VQ862_001442"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:36..38,aa:Val,seq:tac)
     gene            81..151
                     /locus_tag="VQ862_001443"
     tRNA            81..151
                     /locus_tag="VQ862_001443"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:113..115,aa:Gly,seq:tcc)
     gene            186..259
                     /locus_tag="VQ862_001444"
     tRNA            186..259
                     /locus_tag="VQ862_001444"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:220..222,aa:Ile,seq:gat)
     gene            342..431
                     /locus_tag="VQ862_001445"
     tRNA            342..431
                     /locus_tag="VQ862_001445"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:378..380,aa:Ser,seq:tga)
     gene            445..518
                     /locus_tag="VQ862_001446"
     tRNA            445..518
                     /locus_tag="VQ862_001446"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:479..481,aa:Met,seq:cat)
     gene            522..594
                     /locus_tag="VQ862_001447"
     tRNA            522..594
                     /locus_tag="VQ862_001447"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:555..557,aa:Phe,seq:gaa)
     gene            607..687
                     /locus_tag="VQ862_001448"
     tRNA            607..687
                     /locus_tag="VQ862_001448"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:641..643,aa:Tyr,seq:gta)
     gene            692..762
                     /locus_tag="VQ862_001449"
     tRNA            692..762
                     /locus_tag="VQ862_001449"
                     /product="tRNA-Trp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:724..726,aa:Trp,seq:cca)
     gene            777..849
                     /locus_tag="VQ862_001450"
     tRNA            777..849
                     /locus_tag="VQ862_001450"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:810..812,aa:His,seq:gtg)
     gene            863..934
                     /locus_tag="VQ862_001451"
     tRNA            863..934
                     /locus_tag="VQ862_001451"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:895..897,aa:Gln,seq:ttg)
     gene            944..1027
                     /locus_tag="VQ862_001452"
     tRNA            944..1027
                     /locus_tag="VQ862_001452"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:978..980,aa:Leu,seq:caa)
     gene            1134..2411
                     /locus_tag="VQ862_001453"
     CDS             1134..2411
                     /locus_tag="VQ862_001453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001277926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamylcysteine synthetase"
                     /protein_id="HET3115781.1"
                     /translation="MSCSIDLLKHRYLKNIKENPELFVGIELEYPVASLEGDATDVEV
                     IKDLFHYLVSTLDLTVAKVDDFGNLIQLVDPISQDAILFEVSYTTIEFAFGKAETIQE
                     VENRFNNYMNVIQRKLAESNHAIVGCGIHPNWDKNENCPVAYPRYQMLMDYLNLSRNI
                     IKSDLHHFPEYGTFICGSQVQLDISKTNYLRVINAFTQIEAAKAYLFANSEFSGADWD
                     TKISRDIFWEESMHGIYPENVGVNARLLNDEADFFDYLNHSAIFTAERDGQTYYFYPI
                     QAGDYLATSEIQAFALNGDEVIIYPQEKDFETHRSYQYQDLTTRGTVEFRSVCTQPLD
                     RTFASAAFHLGLLVNLDKLEAYLETAPFFKVFGYDYKSLRRQFSKKNLTDEEETTIIE
                     FSKDLLLLAEEGLVVRNKEEMTYLQPLREELSL"
     gene            2487..3971
                     /locus_tag="VQ862_001454"
     CDS             2487..3971
                     /locus_tag="VQ862_001454"
                     /EC_number="4.2.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006595200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine synthase"
                     /protein_id="HET3115782.1"
                     /translation="MTLVYQSTRDANNTVTASQAILQGLATDGGLFTPVTYPKVDLDF
                     DKLKDASYQEVAKLVLSAFLDDFTAEELDYCINNAYDSKFDTPAIAPLVKLDGQYNLE
                     LFHGSTIAFKDMALSILPYFMTTAAKKHGLENKIVILTATSGDTGKAAMAGFADVPGT
                     EIIVFYPKGGVSKVQELQMTTQNGDNTHVIAIDGNFDDAQTNVKHMFNDVALREKLTT
                     NKLQFSSANSMNIGRLVPQIVYYVYAYAQLVKTGEIVAGEKVNFTVPTGNFGNILAAF
                     YAKQIGLPVGKLICASNDNNVLTDFFKTRVYDKKREFKVTTSPSMDILVSSNLERLIF
                     HLLGNNAEKTAELMNALNTQGQYKLTDFDAEILDLFAAEYATEEETAAEIKRVYESDS
                     YIEDPHTAVASAVYRKYQAVTGDVTKTVIASTASPYKFPVVAVEAVTGKAGLTDFEAL
                     AQLHEISGVAVPPAVDGLEIAPIRHKTTVAAADMQAAVEAYLGL"
     gene            4032..5312
                     /locus_tag="VQ862_001455"
     CDS             4032..5312
                     /locus_tag="VQ862_001455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000473957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HET3115783.1"
                     /translation="MFKKNKDILNIALPAMGENFLQMLMGMVDSYLVAHLGLIAISGV
                     SVAGNIITIYQAIFIALGAAISSVISKSIGQKDQSKLAYHVTEALKITLLLSFLLGFL
                     SIFAGKEMIGLLGTERDVAESGGLYLSLVGGSIVLLGLMTSLGALIRATHNPRLPLYV
                     SFLSNALNILFSSLAIFVLDMGIAGVAWGTILSRLVGLVILWSQLKLPYGKLTFGLDK
                     ELLTLALPAAGERLMMRAGDVVIIALVVSFGTEAVAGNAIGEVLTQFNYMPAFGVAMA
                     TVMLLARAVGEDDWKRVASLSKQTFWLSLFLMLPLSFSIYVLGVPLTHLYTTDSLAVE
                     ASVLVTLFSLLGTPMTTGTVIYTAVWQGLGNARLPFYATSIGMWCIRIGTGYLMGIVL
                     GWGLPGIWAGSLLDNGFRWLFLRYRYQRYMSLKG"
     gene            5316..5936
                     /locus_tag="VQ862_001456"
     CDS             5316..5936
                     /locus_tag="VQ862_001456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001172828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HET3115784.1"
                     /translation="MQKTAFIWDLDGTLLDSYEAILSGIEETFAQFSIPYDKEKVREF
                     IFKYSVQNLLVRVAEDRNLDVEVLNQVRAQSLAEKNAQVVLMPGAREVLAWADESGIQ
                     QFIYTHKGNNAFTILKDLGVESYFTEILTSQSGFVRKPSPEAATYLLDKYQLNSDNTY
                     YIGDRTLDVEFAQNSGIQSINFLESTYEGNHRIQALADISRIFETK"
     gene            6102..7280
                     /locus_tag="VQ862_001457"
     CDS             6102..7280
                     /locus_tag="VQ862_001457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HET3115785.1"
                     /translation="MKKRMLLASTVALSFAPVLATQAEEVLWTARSVEQIQNDLTKTD
                     NKTSYTVQYGDTLSTIAEALGVDVTVLANLNKITNMDLIFPETVLTTTVNEAEEVTEV
                     EIQTPQADSSEEVTTATADLTTNQVTVDDQTVQVADLSQPIAEAPKEVASNSEVAETV
                     TAAEEVALSTDSTTPEGQPAETTSPVEEVAPQATTLAEKQETQVSSQTESAVEATTMP
                     VEEKATEATTTSSEAKEVASSNGATAAVSTYQPEETKIISTTYEAPAAPDYAGLAVTK
                     SENAGLQPQTAAFKEEIANLFGITSFSGYRPGDSGDHGKGLAIDFMVPERSELGDKIA
                     EYAIQNMASRGISYIIWKQRFYAPFDSKYGPANTWNPMPDRGSVTENHYDHVHVSMNG
                     "
     gene            7793..8131
                     /locus_tag="VQ862_001458"
     CDS             7793..8131
                     /locus_tag="VQ862_001458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010976657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HET3115786.1"
                     /translation="MTRYQILLFLLEHSPCNQMAVQERLKIDQAALTRNFKILETEGL
                     VERHRNPENQREVLVEAAKYAKEQLVVNPPLQHIKVKEEMESILTEFERTELSRLLNK
                     LVLGIENIEI"
     gene            8142..8510
                     /locus_tag="VQ862_001459"
     CDS             8142..8510
                     /locus_tag="VQ862_001459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1304 domain-containing protein"
                     /protein_id="HET3115787.1"
                     /translation="MSIITIILTTIVALEHFYIFYLESIATQSDATSRVFNMEKEELA
                     HPSVSSLFKNQGIYKALLGVFLLYVIYFSQNLEIVTIFVLFVIGAATYGSLTADKKII
                     LKQGGSAILALISILLFKYT"
     gene            8617..9261
                     /gene="pcp"
                     /locus_tag="VQ862_001460"
     CDS             8617..9261
                     /gene="pcp"
                     /locus_tag="VQ862_001460"
                     /EC_number="3.4.19.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HET3115788.1"
                     /translation="MKVLVTGFEPFGGEKGNPTLEAIKGLPAEIHGAEVRWLEVPTVF
                     HKSAQVLEEEMNRYQPDFVLCIGQAGGRTSVTPERVAINQDDARISDNEDNQPIDRPI
                     RPDGASAYFSSLPIKAMVQAIKKEGLPASVSNTAGTFVCSHLMYQALYLVEKKFPYVK
                     AGFMHIPYMMEQVVNRPTTPTMSLVDIRRGIEAAIGAMIEHGDQELKLVGGETH"
     gene            complement(9289..10146)
                     /locus_tag="VQ862_001461"
     CDS             complement(9289..10146)
                     /locus_tag="VQ862_001461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HET3115789.1"
                     /translation="MNYPKIDLKTIRQESKHFQADTPRLFLLYILPSMLVILSGFLNP
                     LSRIHGTVLEQPFFSILGQILQTYLFPLLVSFIGTILLTSSVYATLTLMKDSKTEPSV
                     KNSLALFDEERFSQTFLTLLLKRFYLFLWSIPNLLGIYLLFYSSFLAKKFVTLHPEFP
                     NLDLSSVETERFLMVFGLYFLASLILIIVGNILYIPQYYAYSQVEFLLCYSLDLGQVP
                     PRRILKTSRSFMKGYKFQHFVLDLQLLPWYFLNWITFGIASFSLLPYIQCTKIMFYRA
                     VLARKRPKA"
     gene            10276..11418
                     /gene="tgt"
                     /locus_tag="VQ862_001462"
     CDS             10276..11418
                     /gene="tgt"
                     /locus_tag="VQ862_001462"
                     /EC_number="2.4.2.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004298827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA guanosine(34) transglycosylase Tgt"
                     /protein_id="HET3115790.1"
                     /translation="MSDSPIKYRLIKKEKHTGARLGEIITPHGTFPTPMFMPVGTQAT
                     VKTQSPEELKEMGSGIILSNTYHLWLRPGDELIARAGGLHKFMNWDQPILTDSGGFQV
                     YSLADSRNITEEGVTFKNHLNGSKMLLSPEKAISIQNNLGSDIMMSFDECPQFYQPYD
                     YVKKSIERTSRWAERGLKAHRRPHDQGLFGIVQGAGFEDLRRQSAHDLVSMDFSGYSI
                     GGLAVGETHEEMNAVLDFTTQLLPENKPRYLMGVGAPDSLIDGVIRGVDMFDCVLPTR
                     IARNGTCMTSQGRLVVKNAQFAEDFTPLDPECDCYTCNNYTRAYLRHLLKADETFGIR
                     LTSYHNLYFLLNLMKQVRQAIMDDNLLEFRKYFVEKYGYNKSGRNF"
     gene            11519..13336
                     /locus_tag="VQ862_001463"
     CDS             11519..13336
                     /locus_tag="VQ862_001463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001220923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyltransferase"
                     /protein_id="HET3115791.1"
                     /translation="MRIKWFSLIRIIGLLLVLLYHFFQTIFPGGFFGVDVFFTFSGFL
                     ITALLIEEFSKNNEIDLIGFFRRRFYRIVPPVVLMVLVTMPFTFLVRQDYVAGIGGQI
                     AGVLGFMTNFYELLTGGSYESQFIPHLFVHNWSLAVEVHYYILWGLAVWFLSKQAKSN
                     GQLKGMIFLLSATAFLISFFSMFIGSFLVTSYSSVYFSSLTHVYPFFLGSMLATIVGV
                     RQTTSLVKQLDKIWDLRKTLVVFGGGFGFLVLLTFFVKFTYLFAYLIGFLLASLAALA
                     MILAARVLHEKTHHIQEPKIISFLADTSYAVYLFHWPFYIIFSQLTSNLLAVLLTLIC
                     SYGFASLSFYVLEPWIAGKNTPILQTLRPLPYIHAILAAGTGILTFIVCMVTLLAPQV
                     GAFETDLTVNGLKQAATNIGQTKVMAERADANSLGIADGTMLIGDSVALRANTALQTA
                     LPGAQINAQVSVTTKTANEIMLNNSQNKFLPKTVVIATGVNNPENYKDDWDSIVKNLP
                     KGHHMILVTPYEGDKTKETYAIVEKAAAYMRELAEKTPYITIADWNQVAKEHPEIWAG
                     TDQVHFGSESSTIEAGAKLYADTIATALQTAQDKPVKSK"
     gene            13489..14640
                     /gene="nagA"
                     /locus_tag="VQ862_001464"
     CDS             13489..14640
                     /gene="nagA"
                     /locus_tag="VQ862_001464"
                     /EC_number="3.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="HET3115792.1"
                     /translation="MPNYIKADQFFYPHGVRRGGYLELVDGKFGKHVEQIPEGAEVID
                     YTGYSIAPGLVDTHIHGYAGVDVMDNNIEGTLHTMSEGLLSTGVTSFLPTTLTATYEQ
                     LLAVTENLGNHYKEATGAKIRGIYYEGPYFTETFKGAQNPTYMRDPGVEEFHSWQKAA
                     NGLLNKIALAPERDGVEDFVRTVTGEGVTVALGHSNATFDEAKKAVDAGASVWVHAYN
                     GMRGLTHRELGMVGAMYQLPHTYAELICDGHHVDPKACEILIKQKGTENIALITDCMT
                     AGGLEDGDYMLGEFPVVVANGTARLKSTGNLAGSILKLKDGLKNVVEWGIANPHEAVM
                     MASFNPAKSVHIDDVCGQIREGYDADFIVLDKDLELVATYLDGVKRYQA"
     gene            14803..15861
                     /locus_tag="VQ862_001465"
     CDS             14803..15861
                     /locus_tag="VQ862_001465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-dependent alcohol dehydrogenase family
                     protein"
                     /protein_id="HET3115793.1"
                     /translation="MKAYTYVKPGLASFVDVDKPVIRKPTDAIVRIVKTTICGTDLHI
                     IKGDVPTCQSGTILGHEGIGIVEEVGEGVSNFKKGDKVLISCVCACGKCYYCKKGIYA
                     HCEDEGGWIFGHLIDGMQAEYLRVPHADNTLYHTPEDLSDEALVMLSDILPTGYEIGV
                     LKGKVEPGCSVAIIGSGPVGLAALLTAQFYSPAKLIMVDLDDNRLETALSFGATHKVN
                     SSDPKKAIKEIYDLTDGRGVDVAIEAVGIPETFDFCQKIIGVDGTVANCGVHGKPVEF
                     DLDKLWIRNINVTTGLVSTNTTPQLLKALESHKIEPEKLVTHYFKLSEIEKAYEVFSK
                     AADHHAIKVIIENDISEA"
     gene            16012..16377
                     /locus_tag="VQ862_001466"
     CDS             16012..16377
                     /locus_tag="VQ862_001466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1033 family protein"
                     /protein_id="HET3115794.1"
                     /translation="MYRVIEMYGDFEPWWFLEGWEEDIVASRKFDQYYDALKYYKTCW
                     FRLEQESPLYKSRSDLMTIFWDPEDQRWCDECDEYLQQYHSLALLQDEQVIPDEKLRS
                     GYEKQTSQERNRSCRMKLK"
     gene            16453..17394
                     /locus_tag="VQ862_001467"
     CDS             16453..17394
                     /locus_tag="VQ862_001467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000249584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II/IV secretion system protein"
                     /protein_id="HET3115795.1"
                     /translation="MVQEIAQEIIRSARKKGTQDIYFVPKLDAYELHMRVGDERCKIG
                     SYDFEKFAAVISHFKFVAGMNVGEKRRSQLGSCDYAYDQKMASLRLSTVGDYRGHESL
                     VIRLLHDEEQDLHFWFQDIEELGKQYRQRGLYLFAGPVGSGKTTLMHELSKSLFKGQQ
                     VMSIEDPVEIKQDDMLQLQLNEAIGLTYENLIKLSLRHRPDLLIIGEIRDSETARAVV
                     RASLTGATVFSTIHAKSIRGVYERLLELGVSEEELAVVLQGVCYQRLIGGGGIVDFAN
                     RDYQEHQAAKWNEQIDQLLKDGHITSLQAETEKISYS"
     gene            17342..18358
                     /locus_tag="VQ862_001468"
     CDS             17342..18358
                     /locus_tag="VQ862_001468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000355375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system F family protein"
                     /protein_id="HET3115796.1"
                     /translation="MDISQVFRLRRKKLATAKQKNIITLFNNLFSSGFHLVETISFLD
                     RSALLDKQCVIQMRVGLSQGKSFSEMMESLGCSSAIVTQLSLAEVHGNLHLSLGKIEE
                     YLDNLAKVKKKLIEVATYPLILLFFLLLIMLGLRNYLLPQLDSSNIATRIIGNLPQIF
                     LGMAGLVSVLALLALTFYKRSSKMNVFSILARLPFIGIFVQTYLTAYYAREWGNMISQ
                     GMELTQIFQMMQEQGSQLFKEIGQDLAQTLKNGREFSQTIGTYPFFRKELSLIIEYGE
                     VKSKLGSELEIYAEKTWEAFFTRVNRTMNLVQPLVFIFVALIIVLLYAAMLMPMYQNM
                     EVNF"
BASE COUNT         5341 a         3287 c         4292 g         5495 t
ORIGIN      
        1 tagggagttt agctcagctg ggagagcatc tgccttacaa gcagagggtc agcggttcga
       61 tcccgttaac tcccatttta gcgggtgtag tttagtggta aaactacagc cttccaagct
      121 gttgtcgcga gttcgattct cgtcacccgc tttgaacttt gttctttgta ccaagttttt
      181 gacttgggcg cgtagctcag gtggttagag cgcacgcctg ataagcgtga ggtcggtggt
      241 tcgagtccac tcgtgcccat agtgtttagt ccattactag gggattggaa tattatctgt
      301 tcactaagag gacacgggct tgttcccgta taaactattt tggaggatta cccaagtccg
      361 gctgaaggga acggtcttga aaaccgtcag gcgtgtaaaa gcgtgcgtgg gttcgaatcc
      421 cacatcctcc ttttatatta ttaacgcggg atggagcagc tcggtagctc gtcgggctca
      481 taacccgaag gtcgtaggtt caaatcctgc tcccgcaata aggctcggta gctcagttgg
      541 tagagcaatg gattgaagct ccatgtgtcg gcggttcgat tccgtctcgc gccatttata
      601 tattttggaa gggtagcgaa gaggctaaac gcggcggact gtaaatccgc tccttcgggt
      661 tcgggggttc gaatccctcc ccttccattt tacgggcata gtttaaaggt agaactaagg
      721 tctccaaaac cttcagtgtg ggttcaattc ctactgcccg tgttaataga attatggcgg
      781 gtgtggtgaa gtggttaaca caccagattg tggctctggc atgcgtgggt tcgatcccca
      841 tcactcgcct attttatatt attggggtat agccaagcgg taaggcaagg gactttgact
      901 ccctcatgcg ttggttcgaa tccagctacc ccagttacta tttgccggcg tggcggaatt
      961 ggcagacgcg ctggactcaa aatccagtgt ccgcaaggac gtgccggttc gaccccggcc
     1021 gccggtatag tatagtgtta ggaacgttgt tattcttcgt tcctttttta tattattttt
     1081 ggtataatta tagttattca aattttattt agattaagaa agtgtagggt agtatgtctt
     1141 gttctatcga tttattaaaa catcggtatt tgaaaaatat taaagaaaat cctgaattgt
     1201 ttgtcggaat tgagttggag tatcctgttg caagtttaga aggggatgct acagatgttg
     1261 aagttataaa ggatctattt cattatttag tttctacttt ggatctcacc gtagcaaagg
     1321 tagatgattt tggcaatctg atccagttag tagatccgat aagtcaggat gctattttat
     1381 ttgaagtttc ctatacaacg attgagtttg catttggtaa ggctgaaacg attcaagagg
     1441 tcgaaaatcg tttcaataat tatatgaatg taattcagag aaagttagct gaatcaaatc
     1501 atgctattgt tggctgtggt atccatccca actgggataa aaatgagaat tgtccagtgg
     1561 cttatccacg ctatcagatg ttgatggatt atttgaattt gagtagaaat attattaaat
     1621 cagatttaca tcatttccct gaatatggta cttttatctg tgggagccag gttcagctgg
     1681 atatttcaaa aaccaactac ttacgggtga ttaatgcttt tactcaaatt gaagcggcta
     1741 aggcttattt atttgcaaac tctgaatttt cgggtgcgga ttgggatacg aaaatttcaa
     1801 gggatatttt ctgggaagaa tctatgcatg gtatctatcc agagaatgtt ggggtcaatg
     1861 ctagactcct taatgatgaa gctgattttt ttgactatct aaatcattct gcgattttta
     1921 ctgcggaacg tgatgggcag acctattatt tttatcctat tcaggctggg gactatttgg
     1981 ctacgtccga aatccaagca tttgctctga atggggatga ggttattatt tacccccaag
     2041 agaaggattt tgaaactcat cgtagttacc agtaccaaga tttaacgact cgaggaacag
     2101 ttgagtttcg tagtgtgtgt acacagccac ttgataggac ttttgcttct gcagcttttc
     2161 acttgggatt attggttaat ttagacaagt tagaagctta cttagaaaca gcacctttct
     2221 ttaaagtatt tggttatgat tacaagtctt taaggagaca attttctaag aaaaatctta
     2281 cagatgagga agaaactacg attattgaat tttccaaaga cttactccta ctagctgagg
     2341 agggactagt ggtgagaaat aaggaagaaa tgacctattt acagcctttg agagaagaat
     2401 tgagcctata atttctctta taaagggaga attttctgaa aaatcatgat ataatggacg
     2461 agactataga taaaggatag agagtaatga cattagttta tcaatcaacg cgtgatgcca
     2521 acaatacagt aactgccagc caagcaattt tgcaaggttt ggcgacggac ggcggtttgt
     2581 ttacaccggt tacttatcca aaggtagatt tggactttga caaattgaaa gatgcttctt
     2641 accaggaagt tgctaagcta gttttgtcag catttttaga tgactttaca gctgaggagt
     2701 tggactactg tatcaacaat gcctacgata gcaaatttga tactccagct attgcaccat
     2761 tagtgaaatt agatgggcaa tacaatttgg aacttttcca tggttcaacg attgccttta
     2821 aggatatggc cttgtctatt ttgccatact ttatgacgac tgctgctaag aaacatggtt
     2881 tggagaacaa gattgttatc ttgacagcga catctggtga cacggggaaa gctgctatgg
     2941 cggggtttgc ggatgtgcct ggtactgaga ttatcgtctt ttatccaaag ggtggtgtca
     3001 gcaaggtaca agagttgcaa atgaccactc agaatggtga caatactcat gttattgcta
     3061 ttgatggtaa ttttgacgat gcgcaaacaa atgtgaagca catgtttaac gacgtggctc
     3121 ttcgtgaaaa attgactacc aacaagttgc aattttcatc agctaactct atgaacattg
     3181 gtcgtctggt gccacaaatt gtttattatg tttatgctta cgctcaattg gttaagactg
     3241 gtgaaattgt agctggtgaa aaggttaact tcacagtacc aacaggaaac tttggaaata
     3301 tcttggctgc cttttatgcc aaacaaatcg gcctaccagt tggcaagcta atctgtgctt
     3361 caaatgacaa taatgtcttg acagacttct ttaaaacacg tgtctatgac aaaaaacgtg
     3421 agtttaaggt aacaaccagc ccatctatgg atatcttggt atcttcaaac ttggagcgct
     3481 tgattttcca tcttttggga aataatgctg aaaagacagc tgaacttatg aatgccttga
     3541 acacgcaagg acaatataag ttgacagact ttgatgcaga gattttggac ctctttgcag
     3601 ctgaatatgc gactgaggaa gaaacagcgg cagaaatcaa gcgtgtttat gagtcagatt
     3661 cttatattga ggatccacat acggcggttg cctcagcagt ttatagaaaa taccaagcgg
     3721 ttactggaga tgtaactaag acagtgattg cttcaacagc tagtccatac aagttcccag
     3781 tagttgcagt agaagctgta actggaaaag caggtttgac agactttgaa gccttggctc
     3841 aattacatga aatctcaggc gttgcagtgc caccagcagt tgatgggctt gaaatagctc
     3901 caattcgtca caagacaaca gtggcagctg ctgacatgca agcagcggtt gaggcttatt
     3961 taggacttta agacagaggg agcaaactcg gtttggaaac caactgagtt tcttttcatc
     4021 aggaggagag attgtttaag aaaaataaag acattcttaa tattgcattg ccagctatgg
     4081 gtgaaaactt tttgcagatg ctaatgggaa tggtggacag ttatttggtt gctcatttag
     4141 gattgatagc tatttcaggg gtttcagtag ctggtaatat tatcaccatt tatcaggcga
     4201 ttttcatcgc tctgggagct gctatttcca gtgttatttc aaaaagcata gggcagaaag
     4261 accagtcgaa gttggcctat catgtgactg aggcgttgaa gattacctta ctattaagtt
     4321 tccttttagg atttttgtcc atcttcgctg ggaaagagat gataggactt ttggggacgg
     4381 agagggatgt agctgagagt ggtggactgt atctatcttt ggtaggcgga tcgattgttc
     4441 tcttaggttt aatgactagt ttgggagcct tgattcgtgc aacgcataat ccacgtctgc
     4501 ctctctatgt tagtttttta tccaatgcct tgaatattct tttttcaagt ctagctattt
     4561 ttgttctgga tatggggata gctggtgttg cttgggggac aattctgtct cgtttggttg
     4621 gtcttgtgat tttgtggtca caattaaaac tgccttatgg gaagctaact tttggtttag
     4681 ataaggaact gttgaccttg gctttaccag cagctggaga gcgacttatg atgagagctg
     4741 gagatgtagt gatcattgcc ttggtcgttt cttttgggac ggaggcagtt gctgggaatg
     4801 caatcggaga agtcttgacc cagtttaact atatgcctgc ctttggtgtc gctatggcaa
     4861 cggtcatgct gttggcccga gcagttggag aggatgattg gaaaagagtt gctagtttga
     4921 gtaaacaaac cttttggctt tctctgttcc tcatgttgcc cctgtccttt agtatatatg
     4981 tcttgggtgt accattaact catctctata cgactgattc tctagcggtg gaggctagtg
     5041 ttctagtgac actgttttca ctacttggta cccctatgac gacaggaaca gtcatctata
     5101 cggcagtctg gcagggatta ggaaatgcac gcctcccttt ttatgcgaca agtataggca
     5161 tgtggtgtat ccgcattggg acaggatatc tgatggggat tgtgcttggt tggggcttgc
     5221 ctggtatttg ggcagggtct ctcttggata atggttttcg ctggttattt ctacgctatc
     5281 gttaccagcg ctatatgagc ttgaaaggat aggaaatgca aaaaacagct tttatttggg
     5341 atttagacgg gactttattg gactcttacg aagcgatttt atcagggatt gaggagactt
     5401 ttgctcagtt ttctattcct tatgataagg agaaggtgag agagtttatc ttcaagtatt
     5461 cggtgcaaaa tttgcttgtg cgggtggcag aagatagaaa tctggatgtt gaggtgctaa
     5521 atcaggtgcg tgcccagagt ctggctgaga agaatgctca ggtagttttg atgccaggtg
     5581 cgcgtgaggt gctagcttgg gcagacgaat caggaattca gcagtttata tatactcata
     5641 aggggaacaa cgcttttacc attctcaagg acttgggggt ggaatcctat tttacagaga
     5701 ttttaaccag tcagagtggc tttgtgcgga agccaagtcc agaagcggct acctatctgc
     5761 tagataagta tcagttgaat tctgataata cttattatat aggggatcgg actctggatg
     5821 tggaatttgc ccagaatagt gggattcaaa gtatcaactt tttagagtct acttatgaag
     5881 ggaatcacag gattcaagcg ttagcagata tttcccgtat ttttgagact aagtgataaa
     5941 aagattgtgt cagttttgtg acagagacct aacaaactat ttcaagtaat ctagtttgtt
     6001 acaaggaata gacagttctg ttaaataggc ccgagagggc tttttttcta cattttttgt
     6061 gttatgatag acaggtactc atttgaaagg aatttgaagg aatgaagaaa agaatgttat
     6121 tagcgtcaac agtagccttg tcatttgccc cagtattggc aactcaagca gaagaagttc
     6181 tttggactgc acgtagtgtt gagcaaatcc aaaacgattt gactaaaacg gacaacaaaa
     6241 caagttatac cgtacagtat ggtgatactt tgagcaccat tgcagaagcc ttgggtgtag
     6301 atgtcacagt gcttgcgaat ctgaacaaaa tcactaatat ggacttgatt ttcccagaaa
     6361 ctgttttgac aacgactgtc aatgaagcag aagaagtaac ggaagttgaa atccaaacac
     6421 ctcaagcaga ttctagtgaa gaagtgacaa ctgcgacagc agatttgaca accaatcaag
     6481 tgaccgttga tgatcaaact gttcaagttg cagatctttc tcaaccaatt gcagaagctc
     6541 caaaagaagt agcatcaaat tcagaagttg cagagacagt gactgctgca gaagaagtgg
     6601 cactatctac agactctact acgccagagg gacaaccagc cgaaacaact agtccagttg
     6661 aagaagtagc tcctcaggca acgactctag ctgagaagca ggaaacacaa gtgagctctc
     6721 aaaccgagtc agcagtggaa gcaactacaa tgccagtaga agaaaaagca accgaagcaa
     6781 ctacaacaag ttcagaagca aaagaagtag catcatcaaa tggagctaca gcagcagttt
     6841 ctacttatca accagaagag acgaaaataa tttcaacaac ttacgaggct ccagctgcgc
     6901 ccgattatgc tggacttgca gtaacaaaat ctgaaaatgc aggtcttcaa ccacaaacag
     6961 ctgcctttaa agaagaaatt gctaacttgt ttggcattac atcctttagt ggttatcgtc
     7021 caggagacag tggagatcac ggaaaaggtt tggctatcga ttttatggta ccagaacgtt
     7081 cagaattagg ggataagatt gcggaatatg ctattcaaaa tatggccagc cgtggcatta
     7141 gttacatcat ctggaaacaa cgtttctatg ctccattcga tagcaaatat gggccagcta
     7201 acacttggaa tccaatgcca gaccgtggta gtgtgacaga aaatcactat gaccacgttc
     7261 acgtttcaat gaatggataa acccgacttg gtaacatcat tttgacgaat gagatctagc
     7321 tttcgtgata ggaagcgatt ctcgttcgtt ttttctttgt catactcttc gaaaatctct
     7381 tcaaacaacg tcagttttat ctgaaacctc aaagctgtgc tttgagcaac ctgcgactag
     7441 cttcctagtt tgctttttga ttttcattga gtatcaattt gaatggaaaa tggaaagtta
     7501 tcatcttgta atgagttaag caacattctt gcaatctatt ttatagtaga ttgaaactag
     7561 aatagtacac aactgcttct aaaacattgt tagaaatcga tttgactgtc ctgatcgatt
     7621 tgtcctgctc ttatttcatt tcactatact ttatattata attgactggt caaatattga
     7681 taaatcaata aaaagagagg ggaagaaatg ctagagattc aagatttact gtatcaactc
     7741 cgcttgtctg agcaagtgag tacgcaattg tttgaaaaag cttgggatta gtttgacacg
     7801 gtatcagatt ttactgtttt tgctggagca ttctccttgt aaccaaatgg cggttcagga
     7861 gcgtttgaaa attgatcagg ctgctttgac acggaatttc aagattttgg aaacggaagg
     7921 tttggtggag cgtcatcgta atcctgaaaa tcagcgggaa gtattggtag aggctgcgaa
     7981 gtatgccaag gagcagttag tggtgaatcc ccctctgcag catatcaagg ttaaggaaga
     8041 gatggaaagt atcttaacag agtttgagag aacagaactc agccgtttat taaataaatt
     8101 ggttttgggt attgaaaata tagaaattta aggagaaata gatgtcaatt attacaatta
     8161 ttttaacaac gatcgttgct ttggagcatt tttacatttt ttatttggaa agtattgcca
     8221 cgcaatcaga tgcgactagt cgtgtattta atatggaaaa ggaagaattg gctcatccgt
     8281 cagtaagttc attgttcaaa aatcaaggga tttataaggc tctgctagga gtctttctct
     8341 tgtatgtcat ttatttctca cagaatttag aaattgtgac tatttttgtc ttatttgtga
     8401 ttggtgctgc gacttacggc tctttaacag cggataaaaa aattattttg aagcaaggtg
     8461 gatcagctat tttggccttg attagtattt tactctttaa atacacttga aggtcgattt
     8521 taatctcgct aatccttttt aatccagaat aagggaaata tgttatactt gtttttaaga
     8581 aaaaagtctc attgaattgg ttttgaggag ttagaaatga aagtattagt gacaggtttt
     8641 gagccctttg gaggggaaaa gggcaatcca actttggagg ccattaaagg tttaccagct
     8701 gaaatccatg gtgctgaggt ccgttggcta gaggtgccga cagtttttca caaatctgct
     8761 caagtattgg aagaagagat gaatcgttat caacctgact ttgtcctttg tattgggcaa
     8821 gctggtggaa gaactagtgt gacacctgaa cgagtggcca ttaatcaaga cgatgcacgc
     8881 atttctgata acgaagataa tcaaccgatt gaccgtccca ttcgcccaga tggtgcttcg
     8941 gcctacttta gtagtttgcc gattaaagcg atggttcaag ctataaaaaa agagggctta
     9001 ccggcctctg tttccaatac ggcagggact tttgtctgca gccatttgat gtatcaggct
     9061 ctctatttgg tagaaaagaa atttccatat gttaaggcag gttttatgca tattccttat
     9121 atgatggaac aggtggtgaa cagaccgact actccaacta tgagtttagt ggatattcgg
     9181 cgagggatag aagcagcaat cggcgctatg atagaacatg gagatcagga actcaagttg
     9241 gtaggcggag aaactcattg atagaaaaaa gcttgagggg aaaaaccttc aagcttttgg
     9301 acgttttcga gccaatactg ctcggtaaaa cataatttta gtgcattgga tataaggtag
     9361 gagtgaaaaa ctagcaatgc caaaggtaat ccaattgagg aagtaccaag gaagaagctg
     9421 taaatctagg acaaagtgct ggaacttgta gcccttcata aaggaacggc tagtttttag
     9481 gattcgtctt ggtgggacct gtcctaggtc tagactataa cagagaagaa attccacctg
     9541 tgaataggca taatactgtg gaatatagag gatatttcct acaatgatca agatgagact
     9601 tgcaagaaag tagagtccaa agaccatgag gaaacgctcg gtttcaactg atgagagatc
     9661 tagatttgga aactcaggat gtagggtgac gaattttttg gctaaaaagc tactataaaa
     9721 gaggaggtaa atcccaagta aattagggat actccataaa aagagataga aacgtttgag
     9781 aagtagggtc aaaaaggttt gagaaaagcg ctcctcatca aagagagcta ggctgttttt
     9841 tacagatggc tccgttttag aatctttcat gagtgtcagt gttgcataga cggaactggt
     9901 caaaagaata gtcccgataa aggagactag tagaggaaag aggtaggttt gaagtatttg
     9961 gccaagtatg ctgaaaaatg gctgttctaa aacagtcccg tggatccgag ataagggatt
    10021 aagaaaacca gataagatga ccagcatact gggaaggata tagaggagaa agagacgggg
    10081 ggtgtcagcc tgaaaatgtt ttgactcctg acgaattgtt tttaaatcaa tttttggata
    10141 gttcattctc ttattatacc atagttctta tacatagttc gtgacagttc ctactttttt
    10201 tgataaaatc atacagtgtg tccttgggca cactgtatga actgggactg tctttcccag
    10261 cttcggaggt aaaaaatgtc agattcacca atcaaatatc gtttgattaa gaaagaaaaa
    10321 cacacaggag ctcgtctagg agaaatcatc actccccacg gtacctttcc gacacctatg
    10381 tttatgccag ttgggacaca agccactgtc aaaactcagt cacctgaaga attgaaggag
    10441 atgggttcgg gaattatcct atcaaacacc tatcatctct ggcttcgccc tggagatgaa
    10501 ctcattgcac gcgctggtgg tctccacaag ttcatgaatt gggaccagcc tatcttgaca
    10561 gatagtggtg gttttcaggt ttattcttta gcagatagcc gtaatatcac agaagaagga
    10621 gtaaccttta aaaatcatct aaatggttct aagatgctcc tatccccaga aaaagccatc
    10681 tctattcaga ataatctggg ttcagacatc atgatgtcct ttgatgaatg tcctcagttt
    10741 tatcaacctt atgactacgt taagaaatcg atcgagcgta ccagccgttg ggctgagcgt
    10801 ggtttgaagg ctcaccgtcg tccacatgac caaggtttgt ttggaattgt gcaaggtgca
    10861 ggatttgaag accttcgccg ccaatcagct cacgatcttg tcagcatgga tttctcaggc
    10921 tactctatcg gtggtttggc agtgggagaa acccatgaag agatgaatgc ggtcttggac
    10981 tttacaactc aactgctgcc tgaaaataaa cctcgttatc tgatgggtgt gggagcgcca
    11041 gatagcttga tcgatggggt cattcgtggg gtggatatgt ttgactgtgt cttaccgact
    11101 cgaattgctc gtaacgggac ttgtatgacc agtcaaggac gtttggttgt gaaaaatgcc
    11161 cagtttgctg aggactttac gccactggat cctgagtgtg attgctacac atgtaataac
    11221 tatacacgcg cttaccttcg tcacctgctc aaggctgatg aaacctttgg tatccgcttg
    11281 actagctacc acaatcttta cttcttgctt aacctgatga agcaagtgcg acaagccatc
    11341 atggatgaca atctcttgga attccgtaag tattttgtgg aaaaatatgg ctataataag
    11401 tcaggacgta atttctaaaa tggaattgat ataagctaaa aatcctaagt tttctcttag
    11461 gatttttctt ctttttttga tagaataaag tgtacaatga aaggaagaat aaactcgtat
    11521 gcgcattaaa tggttttcct tgattaggat tataggttta cttttggtac tcttgtatca
    11581 cttctttcag acgatctttc ctggaggatt tttcggggta gatgtctttt tcacattttc
    11641 aggtttcctg attacagctc tactcattga agaattttct aagaacaatg agattgattt
    11701 gataggattt tttagaagac gcttttatcg gattgtgcca cctgtggttt tgatggtctt
    11761 ggtgaccatg ccttttactt tcttggttcg ccaagactat gttgctggaa ttggtggcca
    11821 gattgcgggc gtcttaggct ttatgaccaa cttctatgaa ctcttaacag gtgggagtta
    11881 tgaatctcag ttcattcctc atttgtttgt tcataattgg agtttggcag ttgaggttca
    11941 ctactatatt ctttggggat tggcagtttg gttcttatcc aaacaagcta aatcaaatgg
    12001 tcagttgaag gggatgatct ttctcttatc tgctactgcc ttcttgatca gtttcttctc
    12061 catgtttatt ggtagttttc tagtgacctc ttattcctct gtttatttct ccagtttaac
    12121 tcatgtctat ccattctttt tgggaagtat gttagcaact attgtaggcg ttcgtcagac
    12181 gacttccctc gtcaagcagt tggataaaat ctgggattta cgaaagactt tagtagtttt
    12241 tggaggaggc tttggtttcc tagttctttt gactttcttt gtcaaattca cttatctttt
    12301 tgcctatctt atcggcttct tgcttgccag tcttgcagct cttgccatga ttctggcggc
    12361 gcgtgtctta catgaaaaga cacatcatat acaggagccg aagattatca gctttttagc
    12421 ggatactagc tatgcggttt atcttttcca ttggcctttc tatatcattt tctcacagtt
    12481 gacatcaaat cttcttgctg tattactgac tctgatttgt tcttatggct ttgccagtct
    12541 gtcattttat gtattggaac cttggattgc aggcaagaac acacctattt tacaaactct
    12601 tcgtcccctg ccttatattc acgcaattct tgcagcaggt acaggaatct tgaccttcat
    12661 tgtctgcatg gtgaccttgt tggcaccaca agtgggagcg tttgagacag acttgactgt
    12721 caatggcttg aagcaagctg caacaaatat tggccagacc aaggtgatgg cagaacgggc
    12781 agatgcaaac agtttgggaa ttgctgatgg cactatgtta attggtgact cagtggcttt
    12841 aagggcaaat acagcactac agacagctct tcctggagca cagattaacg cgcaggtcag
    12901 cgtaacaacc aagaccgcaa atgaaatcat gctaaataat agccagaata aatttttacc
    12961 taagacggtg gtcattgcga ctggggtaaa taatcctgag aattacaagg atgactggga
    13021 cagtatcgtg aaaaatcttc ctaagggaca ccatatgatt ttggtgactc cttatgaggg
    13081 tgataagaca aaagagacct atgccatcgt tgagaaggct gctgcctata tgagagaatt
    13141 ggcagagaag acaccttaca ttacgatagc agattggaat caagttgcga aagagcatcc
    13201 agaaatttgg gctggaacag accaggttca tttcgggagt gagagtagca ctatcgaagc
    13261 aggagcaaaa ttgtatgcag atacgattgc cacagctttg cagacagctc aagacaagcc
    13321 ggttaaatca aaataacttg tattaaaaaa gagaagagtt ggagaaatcc agctctttta
    13381 aaatatctcc aaaaaatagg tctataccat ttacaaataa aaaagaaagg tttataatgt
    13441 aattgacata ataaattgta gaatcaatct tttaaggagg ttaacattat gcctaactat
    13501 attaaagcgg atcagttttt ctacccacac ggagttcgtc gaggtggtta cttggaactt
    13561 gtggacggca agtttggaaa acatgtagag cagattcctg aaggggctga ggtgattgac
    13621 tatacaggtt atagcattgc cccaggtctt gtggatactc atattcatgg atatgcaggt
    13681 gtagatgtga tggacaacaa cattgaaggt acattgcata ctatgagtga aggacttctt
    13741 agtaccggtg ttaccagttt cttacccaca actttaacag ccacttatga gcaattgctt
    13801 gcagtcactg aaaatcttgg aaaccattat aaagaagcaa caggtgctaa gattcgtggg
    13861 atttattatg aaggtccata tttcacagaa acttttaagg gggcacaaaa tccaacttat
    13921 atgagagacc cgggtgttga ggagtttcat tcttggcaaa aagcggcaaa tggcttgctt
    13981 aataaaattg cccttgcacc agaacgtgat ggggtggaag actttgttcg tacagttacg
    14041 ggcgaaggtg tgacggttgc tcttggacat tcaaacgcga cttttgatga agccaaaaaa
    14101 gcagtcgatg ctggagcgag tgtttgggtg catgcctaca atggaatgcg tgggttgact
    14161 caccgtgaat tgggtatggt tggagccatg taccaattgc cacataccta tgcagagttg
    14221 atctgtgatg gtcaccacgt agatccaaag gcttgcgaaa ttcttatcaa acaaaaagga
    14281 acagaaaaca tcgctcttat cacagactgt atgacagctg ggggattgga agacggagat
    14341 tatatgttgg gagaattccc agttgtcgtt gcaaatggaa ctgcacgcct caaatcgaca
    14401 ggtaacttgg caggttctat cctcaaactc aaagatggtt tgaagaatgt ggtcgaatgg
    14461 ggaattgcga atccgcatga agcagtcatg atggccagct tcaacccagc taaatccgtt
    14521 cacatcgatg acgtctgtgg ccaaatccgt gaaggctacg acgctgactt catcgtatta
    14581 gataaagatt tggaattggt agcaacctac ctagatggcg tgaaacgtta tcaagcataa
    14641 gagagaaggc agaagttaga gactaacttc tgctttttta tacagggtac tttactggta
    14701 aataaaaagt taaaaaaatc acaaaaaaag cttgaagaaa caaagaaaaa tgcttacaat
    14761 tgaactataa atattacaaa taaaaaaacg gaggagtgct ttatgaaagc ctatacttat
    14821 gttaaaccag gacttgcttc ttttgttgat gtagacaaac cagttattcg caagccaaca
    14881 gacgctattg tgcgtattgt aaaaaccact atttgtggaa cagacctcca tattatcaaa
    14941 ggggatgttc ctacttgcca aagtggtacc attcttggcc acgaagggat tgggattgtt
    15001 gaagaagttg gggaaggagt ttccaacttc aaaaaaggtg acaaggtctt gatttcttgc
    15061 gtctgtgcct gtggtaaatg ctactactgt aaaaaaggaa tttatgccca ctgtgaagac
    15121 gaagggggct ggattttcgg tcacttgatt gatggtatgc aggctgaata tctacgtgtc
    15181 cctcatgcag ataatactct ttaccatact ccagaagact tgtcagatga agctttggtt
    15241 atgctgtcag acattctgcc tactggatat gaaattggtg tcttaaaagg gaaagtagaa
    15301 cctggttgca gcgtagccat tattggttca ggtccagttg gattggctgc tcttttaaca
    15361 gcccaattct attcaccagc taaattgatt atggtagacc tagacgataa ccgcttggaa
    15421 actgccctat cattcggtgc gactcataag gttaattctt cagaccctaa aaaagccatt
    15481 aaagaaattt atgatttgac agatggtcgt ggtgtggatg tcgctatcga agctgtaggg
    15541 attcctgaaa catttgattt ctgtcaaaag attatcggtg tagacggaac ggttgccaac
    15601 tgtggtgtgc atggtaaacc agttgaattc gatttagata aactttggat tcgcaacatc
    15661 aatgtaacaa ctggtttggt atctacaaat acgactccac aattgttgaa agcacttgaa
    15721 agtcataaga ttgaaccgga aaaattggta actcactatt tcaaactcag tgaaattgaa
    15781 aaagcctacg aagtcttcag taaggcagca gaccaccatg ccattaaggt cattatcgaa
    15841 aacgatatct cagaagccta agtagtaaaa atatttttgt acataagcaa atagaaattc
    15901 agtcatccat cagatggctg gattttttat caaaaaatta agaaatgagc atatttcttt
    15961 ccttgtctgg cggaattggt tataatatac ggtacaaagg aatgaatgaa tatgtatcgt
    16021 gttatagaaa tgtacggaga ttttgaaccg tggtggttct tagaaggttg ggaagaagat
    16081 attgtagcaa gtagaaaatt tgaccagtat tatgatgctc tcaaatacta caaaacttgc
    16141 tggtttagat tggaacaaga atcccctctt tataaaagta gaagcgactt gatgaccatt
    16201 ttttgggacc cggaagacca acgctggtgt gatgaatgtg atgagtattt acaacaatac
    16261 cattctttgg ctcttttgca ggatgagcag gttatcccag acgaaaaact acgctcaggc
    16321 tatgaaaaac aaaccagtca ggaaaggaat cgttcttgcc gtatgaaatt aaaatagaga
    16381 aaagtaactt ttttggagtt gcttttttta tttttctaac gctttgcgaa tagtataggt
    16441 gaggaggtaa gtatggttca agaaattgca caagaaatca ttcgttcagc tcggaaaaaa
    16501 gggacgcagg atatttattt tgtccctaag ttagacgcct atgagcttca tatgagggta
    16561 ggagacgagc gctgtaaaat tggtagctat gattttgaaa agtttgcagc cgttatcagt
    16621 cactttaagt ttgtggcggg tatgaatgtg ggagaaaaaa gacgtagtca actgggttcc
    16681 tgtgattatg cctatgacca gaagatggcg tctctacgtt tatctactgt aggcgattat
    16741 cggggacatg agagtttggt tatccgtttg ttgcacgatg aggagcagga cttgcatttt
    16801 tggtttcagg atattgaaga attaggcaag cagtacaggc aacggggact ctatcttttt
    16861 gctggcccgg ttgggagtgg taagacgacc ttgatgcatg aattgtccaa gtcactcttt
    16921 aaaggacagc aagttatgtc catcgaagat cctgtcgaaa tcaagcagga cgacatgctt
    16981 cagttgcagt tgaacgaagc aatcggccta acctatgaaa atctaatcaa actttccttg
    17041 cgtcatcgac cagatctctt gattatcgga gaaattcgtg acagcgagac ggcgcgtgca
    17101 gtggtcagag ctagtttgac aggtgcgaca gtcttttcaa ccattcacgc caagagtatc
    17161 cgaggtgttt atgagcgtct gctggagttg ggtgtgagtg aagaagaatt ggcagttgtt
    17221 ctgcaaggag tctgctacca gagattaatc gggggaggag gaatcgttga ctttgcaaac
    17281 agagattatc aagaacacca agcagccaag tggaatgagc aaattgacca gcttcttaaa
    17341 gatggacata tcacaagtct tcaggctgag acggaaaaaa ttagctacag ctaagcaaaa
    17401 aaatatcatc accctattta acaatctctt ttctagcggt tttcatctgg tggagactat
    17461 ctccttttta gataggagtg ctttgttgga caagcagtgt gtgatccaga tgcgtgtggg
    17521 cttgtctcag gggaaatcat tctcagaaat gatggaaagt ttgggatgtt caagtgctat
    17581 tgtcactcag ttatccctag ctgaagttca tggcaatctc cacctgagtt tgggaaagat
    17641 agaagaatat ctggacaatc tggccaaggt caagaaaaaa ttgattgaag tagcgaccta
    17701 tcccttgatt ttgctgtttt ttcttctctt aatcatgctg gggctacgga attacctgct
    17761 cccacaactg gatagtagca atattgccac ccgaattatc ggtaatctgc cccaaatttt
    17821 tctaggcatg gcagggcttg tttccgtgct tgccctttta gcactaactt tttataaaag
    17881 aagttctaag atgaatgtct tttctatctt agcacgcctt ccctttattg gaatctttgt
    17941 gcagacctat ttgacagcct attatgcacg tgaatggggg aatatgattt cacagggaat
    18001 ggagttgacg cagatttttc aaatgatgca ggaacaaggt tcccagctct ttaaagaaat
    18061 cggtcaagat ctggctcaaa ccctgaaaaa tggccgtgaa ttttctcaga cgataggaac
    18121 ctatcctttc tttaggaagg aattgagtct catcatagag tatggggaag ttaagtccaa
    18181 gctgggtagt gagttggaaa tctatgctga aaaaacttgg gaagcctttt ttacccgagt
    18241 caaccgcacc atgaatttgg tgcagccact ggtttttatc tttgtggcac tgattatcgt
    18301 tttactttat gcggcaatgc tcatgcccat gtatcaaaat atggaggtaa atttttaaaa
    18361 tgaaaaaaat gatgacattc ttgaaaaaag ctaaggttaa agcttttaca ttggt
//
LOCUS       DAVBOD010000040        18414 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 640-05
            SAMEA1012484-rid20186543.denovo.040, whole genome shotgun sequence.
ACCESSION   DAVBOD010000040 DAVBOD010000000
VERSION     DAVBOD010000040.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012484
            Sequence Read Archive: ERR059358
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 18414)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18414)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979948.1
            Genome Coverage       :: 595x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:03:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,266
            CDSs (total)                      :: 2,219
            Genes (coding)                    :: 2,091
            CDSs (with protein)               :: 2,091
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 71 of 128
            Pseudo Genes (incomplete)         :: 50 of 128
            Pseudo Genes (internal stop)      :: 33 of 128
            Pseudo Genes (multiple problems)  :: 22 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18414
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012484-rid20186543.denovo.040"
                     /strain="NIG 640-05"
                     /db_xref="taxon:1313"
     gene            complement(62..859)
                     /gene="proC"
                     /locus_tag="VQ862_001469"
     CDS             complement(62..859)
                     /gene="proC"
                     /locus_tag="VQ862_001469"
                     /EC_number="1.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="HET3115797.1"
                     /translation="MKIGFIGLGNMGASLAKSVLQARPSDEILLANRSQVKVDAFIAN
                     FGGQTSNNEEIFEEADVIFLGVKPAQFSELLSQYQTILEKRESLLLISMAAGLTLEKL
                     ASLIPSQHRIIRMMPNTPASIGQGVISYALSPNCRAEDSELFCQLLAKAGLLVELGES
                     LINAATGLAGCGPAFVYLFIEALADAGVQTGLPRETALKMAAQTVVGAGQLVLESQQH
                     PGVLKDQVCSPGGSTIAGVASLEAHAFRGTVMDAVHQAYKRTQELGK"
     gene            complement(863..2125)
                     /locus_tag="VQ862_001470"
     CDS             complement(863..2125)
                     /locus_tag="VQ862_001470"
                     /EC_number="1.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate-5-semialdehyde dehydrogenase"
                     /protein_id="HET3115798.1"
                     /translation="MVSRQEQFEQVQAVKKSINTASEEVKNQALLAMADHLVAATEEI
                     LAANALDMAAAKGKISDVMLDRLYLDADRIEAMARGIREVVALPDPIGEVLETSQLEN
                     GLVITKKRVAMGVIGIIYESRPNVTSDAAALTLKSGNAVVLRSGKDAYQTTHAIVTAL
                     KKGLETTTIHPNVIQLVEDTSRESSYAMMKAKGYLDLLIPRGGAGLINAVVENAIVPV
                     IETGTGIVHVYVDKDADEDKALSIINNAKTSRPSVCNAMEVLLVHENKAASILPRLDQ
                     MLVAERKEAGLEPIQFRLDSKASQFVSGQAAETQDFDTEFLDYVLAVKVVSSLEEAVS
                     HIESHSTHHSDAIVTENAEAAAYFTDQVDSAAVYVNASTRFTDGGQFGLGCEMGISTQ
                     KLHARGPMGLKELTSYKYVVTGDGQIRE"
     gene            complement(2135..3265)
                     /locus_tag="VQ862_001471"
     CDS             complement(2135..3265)
                     /locus_tag="VQ862_001471"
                     /EC_number="2.7.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004240022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate 5-kinase"
                     /protein_id="HET3115799.1"
                     /translation="MNNRSETMKYKRIVFKVGTSSLTNEDGSLSRSKVKDITQQLAML
                     HEAGHELILVSSGAIAAGFGALGFKKRPTKIADKQASAAVGQGLLLEEYTTNLLLRQI
                     VSAQILLTQDDFVDKRRYKNAHQALSVLLNRGAIPIINENDSVVIDELKVGDNDTLSA
                     QVAAMVQADLLVFLTDVDGLYTGNPNSDPRAKRLERIETINREIIDMAGGAGSSNGTG
                     GMLTKIKAATIATESGVPVYICSSLKSDSMIEAAEETEDGSYFVAQEKGLRTQKQWLA
                     FYAQSQGSIWVDKGAAEALSQHGKSLLLSGIVEAEGAFSYGDIVTVFDKESGKSLGKG
                     RVQFGASALEDMLRSQKAKGVLIYRDDWISITPEIQLLFTEF"
     gene            complement(3345..5228)
                     /gene="cbpE"
                     /locus_tag="VQ862_001472"
                     /gene_synonym="pce"
     CDS             complement(3345..5228)
                     /gene="cbpE"
                     /locus_tag="VQ862_001472"
                     /gene_synonym="pce"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000728269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine esterase CbpE"
                     /protein_id="HET3115800.1"
                     /translation="MKKKLTSLALVGAFLGLSWYGNVQAQESSGNKIHFINVQEGGSD
                     AIILESNGHFAMVDTGEDYDFPDGSDSRYPWREGIETSYKHVLTDRVFRRLKELGVQK
                     LDFILVTHTHSDHIGNVDELLSTYPVDRVYLKKYSDNRITNSERLWDNLYGYDKVLQT
                     ASEKGVSVIQNITQGDAHFQFGDMDIQLYNYENETDSSGELKKIWDDNSNSLISVVKV
                     NGKKIYLGGDLDNVHGAEDKYGPLIGKVDLMKFNHHHDTNKSNTKDFIKNLSPSLIVQ
                     TSDSLPWKNGVDSEYVNWLKERGIERINAASKDYDATVFDIRQDGLVNISTSYKPIPS
                     FQAGWHKSSYGNWWYQAPDSTGEYAVGWNEIKGEWYYFNQTGILLQNQWKKWNNRWFY
                     LTDSGVAAKNWKKIAGIWYYFNKENQMEIGWIQDKEQWYYLDVDGSMKTGWLQYKGQW
                     YYFAPSGEMKTGWVKDKEAWYYMDSTGIMKTGEIEVAGHHYYLEESGAMKQGWLKKAN
                     DWYFYKTGGSRAIGWIKDKDKWYFLKENGQLLVNGKTPEGYTVDSSGAWLVDVPIEKS
                     ATIKTTSHSEIKESKEVVKKDLENKETSQHESVTNSSTSQDLTSSTSQSSETSVNKSE
                     SEQ"
     gene            complement(5231..6118)
                     /locus_tag="VQ862_001473"
     CDS             complement(5231..6118)
                     /locus_tag="VQ862_001473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HET3115801.1"
                     /translation="MEIKIETGGLRLDKALSDLTELSRSLANEQIKSGQVLVNGQVKK
                     AKYTVQEGDVVTYHVPEPEVLEYVAEDLPLEIVYQDEDVAVVNKPQGMVVHPSAGHTS
                     GTLVNALMYHIKDLSGINGVLRPGIVHRIDKDTSGLLMIAKNDDAHLALAQELKDKKS
                     LRKYWAIVHGNLPNDRGVIEAPIGRSEKDRKKQAVIAKGKPAVTRFHVLERFGDYSLV
                     ELQLETGRTHQIRVHMAYIDHPVAGDEVYGPRKTLKGHGQFLHAKTLGFTHPRTGKTL
                     EFKADIPEIFKETLERLRK"
     gene            complement(6108..6569)
                     /locus_tag="VQ862_001474"
     CDS             complement(6108..6569)
                     /locus_tag="VQ862_001474"
                     /EC_number="3.4.23.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase II"
                     /protein_id="HET3115802.1"
                     /translation="MKKRAIVAVIVLLLIGLDQLVKSYIVQQIPLGEVRSWIPNFVSL
                     TYLQNRGAAFSILQDQQLLFAVITLVVVIGAIWYLHKHMEDSFWMVLGLTLIIAGGLG
                     NFIDRASQGFVVDMFHLDFINFAIFNVADSYLTVGVIILLIAMLKEEINGN"
     gene            complement(6566..7474)
                     /locus_tag="VQ862_001475"
     CDS             complement(6566..7474)
                     /locus_tag="VQ862_001475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001025716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HET3115803.1"
                     /translation="MNIQQLRYVVAIANSGTFREAAEKMYVSQPSLSISVRDLEKELG
                     FKIFRRTSSGTFLTRRGMEFYEKAQELVKGFDIFQNQYANPEEEKDEFSVASQHYDFL
                     PPTITAFSERYPDYKNFRIFESTTVQILDEVAQGHSEIGIIYLNNQNKKGIMQRVEKL
                     GLEVIELIPFHTHIYLCEGHPLAQKEELVMEDLADLPTVRFTQEKDEYLYYSENFVDT
                     SASSQMFNVTDRATLNGILERTDAYATGSGFLDSDSVNGITVIRLKDNLDNRMVYVKR
                     EEVELSQAGTLFVEVMQEYFDQKRKS"
     gene            7467..7664
                     /locus_tag="VQ862_001476"
     CDS             7467..7664
                     /locus_tag="VQ862_001476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET3115804.1"
                     /translation="MFIFYPQLLYLFIIPYFRSFPKRKKEHPILLNYLHYLPFSRQSY
                     FQNQFKKISGYTPLQYRKEKR"
     gene            complement(7716..8387)
                     /locus_tag="VQ862_001477"
     CDS             complement(7716..8387)
                     /locus_tag="VQ862_001477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET3115805.1"
                     /translation="MKKRAIQILLALSLIFYKSTWFWRVFNHLAKPYLPASREFFQIL
                     LLMESGVLFLAVIYLLVFAGKKIFHFKWQLRYFIYLLLGYIISYMSDFLFSYFISLSS
                     NQISLNETVEMMGRQEFPYFLLIVCFIAPIAEELIYRGVLMTTFFKNSPWYGDVLLSA
                     IIFGYIHINFALTPLAFFIYASGGLILALLYRMTKNLYYPILVHILINITAFWDVWLL
                     LFSGS"
     gene            complement(8441..8662)
                     /locus_tag="VQ862_001478"
     CDS             complement(8441..8662)
                     /locus_tag="VQ862_001478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000602450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SP_0924 family bacteriocin-like peptide"
                     /protein_id="HET3115806.1"
                     /translation="MILMTKNINLTNEELELIQGGADPYGKNPNGRYDWEIEPVLTLP
                     VHGFCPRGTYDLGYIGGGNHLCKGSAARF"
     gene            8934..9743
                     /locus_tag="VQ862_001479"
     CDS             8934..9743
                     /locus_tag="VQ862_001479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000593565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HET3115807.1"
                     /translation="MIKLLALDMDGTLLNEAKEIPQAHIAAIHQAIEKGVKLVLCTGR
                     PLFGVLPYYKKLGLDLQNEYVIVNNGCSTHQTSDWGLVDWQELSPADIEYLYDLAEKS
                     DVQLTLFDESHYFVLGGKPNQVIENDAKLVFSDLTEISLEEATSGKLRMFQGMFLGTK
                     EQTDDFEQRFAEELCQRFSGVRSQPVIYEAMPLGTTKATALSRLAEILKIDSSEIMAM
                     GDANNDIEMLQFAGLGIAMGNASDYVKSLADAVTSSNEEDGVARAIEKYIL"
     gene            complement(9924..10799)
                     /gene="aguB"
                     /locus_tag="VQ862_001480"
     CDS             complement(9924..10799)
                     /gene="aguB"
                     /locus_tag="VQ862_001480"
                     /EC_number="3.5.1.53"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001246759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-carbamoylputrescine amidase"
                     /protein_id="HET3115808.1"
                     /translation="MRNVRVATIQMQCAKDVATNIQTAERLVRQAAEQGAQIILLPEL
                     FEHPYFCQERQYDYYQYAQSVAENTAIQHFKVIAKELQVVLPISFYEKDGNVLYNSIA
                     VIDADGEVLGVYRKTHIPDDHYYQEKFYFTPGNTGFKVWNTRYAKIGIGICWDQWFPE
                     TARCLALNGAELLFYPTAIGSEPILDTDSCGHWQRTMQGHAAANIVPVIAANRYGLEE
                     VTPSEENGGQSSSLDFYGSSFMTDETGAILERAERQEEAVLLATYDLDKGASERLNWG
                     LFRDRRPEMYRQITD"
     gene            complement(10809..11894)
                     /gene="aguA"
                     /locus_tag="VQ862_001481"
     CDS             complement(10809..11894)
                     /gene="aguA"
                     /locus_tag="VQ862_001481"
                     /EC_number="3.5.3.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="agmatine deiminase"
                     /protein_id="HET3115809.1"
                     /translation="MMDSPKKLGYHMPAEYEPHHGTLMIWPTRPGSWPFQGKAAKRAF
                     TQIIETIAEGERVYLLVEQAYLSEAQSYLGDKVVYLDIPTNDAWARDTGPTILVNDKG
                     KKLAVDWAFNAWGGTYDGLYQDYEEDDQVASRFAEALGRPVYDAKPFVLEGGAIHSDG
                     QGTILVTESCLLSPGRNPNLTKEEIENTLLESLGAEKVIWLPYGIYQDETNEHVDNVA
                     AFVGPAELVLAWTDDENDPQYAMSKADLELLEQETDAKGCHFTIHKLPIPAVRQVVTE
                     EDLPGYIYEEGEEKRYAGERLAASYVNFYIANKAVLVPQFEDVNDQVALDILSKCFPD
                     RKVVGIPARDILLGGGNIHCITQQIPE"
     gene            complement(11891..13018)
                     /gene="nspC"
                     /locus_tag="VQ862_001482"
     CDS             complement(11891..13018)
                     /gene="nspC"
                     /locus_tag="VQ862_001482"
                     /EC_number="4.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxynorspermidine decarboxylase"
                     /protein_id="HET3115810.1"
                     /translation="MKLEQVPTPAYVIDLAKLEANCRILQYVQEEAGCKVLLAQKAYS
                     LYKTYPLISQYLSGTTASGLYEAKLAREEFPGEVHVFAPAFKDADLEELLEIMDHIVF
                     NSERQLRKHGPRCREAGVSVGLRLNPQCSTQGDHALYDPCAPGSRFGVTIDKIPSDLL
                     DLVDGLHFHTLCEQGVDDLQTTLKAVEEQFGPYLHEVKWLNMGGGHHITREGYDVDLL
                     ISEIKRIRKTYNLEIYIEPGEAIALNAGYLATEVLDIVENGMEILVLDASATCHMPDV
                     LEMPYRPSLRNGFEAQEKAHTYRLSSNTCLTGDVIGDYSFENPVQIGDRLYFQDMAIY
                     SFVKNNTFNGIGLPSLYLMDEQGDCSLLKAFGYQDFKGRLS"
     gene            complement(13018..14277)
                     /locus_tag="VQ862_001483"
     CDS             complement(13018..14277)
                     /locus_tag="VQ862_001483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000088792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="saccharopine dehydrogenase family protein"
                     /protein_id="HET3115811.1"
                     /translation="MSRLLVIGCGGVAQVAISKICQDSETFTEIMIASRTKSKCDDLK
                     AKLEGKTSTKIETAALDADKVEEVIALIESYKPEAVLNVALPYQDLTIMDACLATGVH
                     YIDTANYEAEDTEDPEWRAIYEKRCKELGFTAYFDYSWQWAYQEKFKEAGLTALLGSG
                     FDPGVTSVFSAYALKHYFDEIHYIDILDCNGGDHGYPFATNFNPEINLREVSAPGSYW
                     EDGKWVEVEAMSIKREYDFPQVGQKDMYLLHHEEIESLAKNIPGVKRIRFFMTFGQSY
                     LTHMKCLENVGLLRTDTINFNGQEIVPIQFLKALLPDPASLGPRTVGKTNIGCIFTGV
                     KDGVEKTIYIYNVCDHQECYAEVGSQAISYTTGVPAMIGTKLVMNGTWKQAGVYNLEE
                     LDPDPFMEALNEYGLPWVVVENPQMVD"
     gene            complement(14274..15134)
                     /gene="speE"
                     /locus_tag="VQ862_001484"
     CDS             complement(14274..15134)
                     /gene="speE"
                     /locus_tag="VQ862_001484"
                     /EC_number="2.5.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyamine aminopropyltransferase"
                     /protein_id="HET3115812.1"
                     /translation="MDLWFSEVHTPDVKLSLRTAKQLYAGKSEWQDIEVLDTPAFGKI
                     LILNGHVLFSDADDFVYNEMTVHVPMAVHPNPKKVLVIGGGDGGVAQVLTLYPELEQI
                     DIVEPDEMLVEVCREYFPDFAAGLDDPRVTIYYQNGLRFLRNCEDDYDIIINDATDPF
                     GHTEGLFTKEFYGNSYRALKEDGIMIYQHGSPFFDEDESACRSMHRKVNQSFPISRVY
                     QAHIPTSPAGYWLFGFASKKYHPVKDFDKEGWKKRQLFTEYYTANLHVGSFMLPKYVE
                     DILEEEEGKK"
     gene            15390..16105
                     /locus_tag="VQ862_001485"
                     /pseudo
     CDS             15390..16105
                     /locus_tag="VQ862_001485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809094.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
     gene            complement(16071..17546)
                     /locus_tag="VQ862_001486"
     CDS             complement(16071..17546)
                     /locus_tag="VQ862_001486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000661022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HET3115813.1"
                     /translation="MKEVDQNQAPIYEALVKLRKKRIVPFDVPGHKRGRGNPELVELL
                     GEKCVGIDVNSMKPLDNLGHPISIIRDAEELAADAFGASHAFLMIGGTTSSVQTMILA
                     TCKAGDKIILPRNVHKSAINALVLCGAIPIYIEMSVDPKIGIALGLENDRVAQAIKDH
                     PDAKAILINNPTYYGICSDLKGLTEMAHEAGMMVLVDEAHGAHLHFTGKLPISAMDAG
                     ADMAAVSMHKSGGSLTQSSLLLIGEQMNPEYVRQIINLTQSTSASYLLMASLDISRRN
                     LALRGKESFEEVIELSEYARHEINAIGGYYAYSKELIDGVSVCDFDVTKLSVYTQGIG
                     LTGIEVYDLLRDEYDIQIEFGDIGNILAYISIGDRIQDIERLVGALADIKRLYSRDGK
                     DLIAGEYIQPELVLSPQEAFYSERKSLTLDESVGQVCGEFVMCYPPGIPILAPGERIT
                     REIVDYIQFAKERGCSLQGTEDPEVNHINVIKRKTNYKKSQ"
     gene            18253..>18414
                     /locus_tag="VQ862_001487"
     CDS             18253..>18414
                     /locus_tag="VQ862_001487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HET3115814.1"
                     /translation="MQDNYTTKGKHLTIDSRRLIERWKKEGKSNREVASLLGKAPQTI
                     HTEIKRGTVR"
BASE COUNT         5425 a         4217 c         3369 g         5403 t
ORIGIN      
        1 agtttgaatt tgattttcga agagtatcaa ccaccataaa agaggcagat aaaactacct
       61 cttatttacc tagttcttgt gttcgtttat aggcttgatg aactgcatcc atgaccgttc
      121 ctcgaaaagc atgcgcttct aggcttgcta cgccagcaat agtcgaaccg cctggactac
      181 aaacttgatc tttcaaaact ccaggatgtt gctggctttc taggaccaat tgcccagctc
      241 ctaccacagt ttgggctgcc attttcaagg ctgtttctcg tggtaatccc gtctgaacac
      301 ctgcatctgc caaggcctca ataaagagat agacaaaggc tggtccacaa cctgcaagac
      361 ctgtcgctgc attgattaag ctttctccta attcaaccaa gagaccagcc ttggctaaaa
      421 gctgacaaaa gagctcactg tcctcagccc tgcaattagg agacaaggca taactaatca
      481 ctccttgccc gatagaagca ggggtattag gcatcatacg aataattcgg tgttggcttg
      541 ggataagact tgctagtttt tctaaggtca atccagctgc catcgaaatc aaaagaagac
      601 tttctctttt ttcaaggatg gtctggtatt gagaaagcag ttcagaaaac tgagcaggct
      661 taacacctag aaaaatcaca tctgcttctt cgaatatttc ttcattgtta gaagtctgac
      721 caccgaagtt agcgatgaaa gcatccacct tgacttgact acgattggca aggagaatct
      781 catctgacgg tctagcctgc aagacagact tggctaaact agcacccata ttccccaaac
      841 cgataaatcc aatcttcatc ccttactccc ttatctgtcc atcaccagtg accacatact
      901 tgtagctagt caattccttc aagcccatgg gaccacgcgc gtgcaatttc tgagtagaaa
      961 tccccatttc acaaccaaga ccaaattgtc ctccatctgt gaaacgagtt gaggcattaa
     1021 catacaccgc tgcagagtcc acttgatctg taaagtatgc tgcagcttca gcattttccg
     1081 tcacaatagc atccgaatga tgagtgctgt gggattcaat gtgcgaaacc gcttcttcta
     1141 aactgctcac aaccttaaca gcaaggacat agtctaaaaa ctcggtgtca aagtcttggg
     1201 tctcagctgc ttgacctgaa acaaactggc ttgctttgct atccaagcgg aattgaattg
     1261 gttccagtcc agcttcctta cgctctgcaa ccagcatttg atccaagcga ggaaggatgc
     1321 ttgctgcctt gttttcatga accagcagaa cctccatggc attacaaaca gaaggacgac
     1381 tggttttagc attgttgatg atagacagcg ccttgtcttc gtctgcatcc ttatccacat
     1441 agacatggac aatcccagtc cctgtctcga taacaggtac aatcgcattc tcaaccactg
     1501 cattgatcaa gccagctcct ccacgaggaa tgagaaggtc tagatagccc ttggccttca
     1561 tcatagcata actactttca cggctagtat cctccaccag ttgaatcaca tttggatgaa
     1621 tagtagtcgt ctccaagccc ttcttcaagg ctgtgacaat ggcatgggtt gtttgatagg
     1681 catccttacc actacgaaga acaaccgcat ttccactctt aagagtcaaa gcagccgcat
     1741 cagacgtcac atttggacgg ctttcataga taataccgat gacacccata gctacacgtt
     1801 tttttgtgat aaccaaacca ttttcaagct gacttgtttc taaaacttca ccgattggat
     1861 ctggtaaggc aaccacttca cgaattcctc ttgccatcgc ttctatacga tctgcatcca
     1921 aataaagacg atccaacatc acatctgaga ttttcccctt agccgctgcc atatcgaggg
     1981 cattagccgc taaaatttcc tcagtagcag ccactaagtg atcagccatg gctagcaagg
     2041 cttggttttt cacttcttca ctagctgtgt taatcgattt tttaacagcc tgtacctgtt
     2101 caaattgttc ttgtctactc accatagttt acctctaaaa ttctgtaaaa agtagttgga
     2161 tttcaggagt aatggaaatc cagtcgtcac ggtaaatcaa gacacccttg gctttttgag
     2221 aacgcaacat atcctccaaa gcagatgctc caaattgcac gcgtcctttt ccaagtgatt
     2281 ttccactttc cttgtcaaat actgtcacga tatcaccgta agaaaaggct ccttctgctt
     2341 caacgatacc agataagaga agactctttc catgttgaga gagagcttcc gcagcccctt
     2401 tatcaaccca aatagaacct tgactctgag catagaaggc aagccattgt ttctgggtac
     2461 gaagcccctt ctcttgagca acaaagtaag aaccatcctc ggtctcctct gccgcctcaa
     2521 tcatggaatc tgatttcaag gatgagcaaa tataaacagg aactcctgat tccgtcgcga
     2581 tagttgcagc cttgattttg gttaacatac ccccagttcc gtttgacgaa cctgctccac
     2641 cagccatatc aataatctca cgattgatgg tctcgattct ctccaagcgt ttggctcttg
     2701 gatctgaatt aggatttcca gtatagagac cgtccacatc tgtcaagaaa actaaaaggt
     2761 ctgcttggac catcgccgct acttgagcac ttagagtgtc attgtcccca accttgagct
     2821 catcaataac gacactatca ttctcattga tgataggaat tgccccacgg ttgagcaaaa
     2881 ccgacaaagc ctgatgggca tttttataac gacgcttatc cacaaagtca tcttgggtca
     2941 gcaagatttg tgcagaaacg atttgacgca agagaagatt ggtcgtatat tcttccaaca
     3001 aaagtccctg ccctaccgct gctgaagcct gtttatcagc aattttagtc ggacgctttt
     3061 taaatcctaa ggctccaaaa ccagccgcaa tggcacctga agacaccaaa atcaactcat
     3121 gaccagcctc gtgcagcata gccaactgct gggtaatatc ctttacctta ctacgtgata
     3181 aacttccatc ctcatttgtc agagaagaag tacccacctt aaagacaatc cgtttgtatt
     3241 tcatagtctc actccgatta ttcatattta tccattataa catgaataac aggaaataga
     3301 aaagagttga taggaaaaag aaggccctaa aaccttcttt tctactactg ttctgattcc
     3361 gatttgttta cactcgtttc agagctttgt gaagttgagg atgtcaaatc ttgactagtt
     3421 gaagaatttg taacactttc atgttgactc gtttctttat tttcaagatc ctttttcact
     3481 acttctttgg attcttttat ttctgaatga cttgtagttt taattgtagc agatttctcg
     3541 atcggaacat ccactaacca ggcaccactt gaatccacag tatagccttc tggtgtctta
     3601 ccattcacaa gtaattgacc attttctttc aagaagtacc atttatcctt gtctttaatc
     3661 caacctatag ctcgtgaacc acctgtcttg tagaaatacc aatcatttgc ctttttaagc
     3721 cagccttgct tcatagctcc tgattcttct agatagtaat gatgtccagc aacttctatc
     3781 tcacctgtct tcatgatacc agtagaatcc atatagtacc aggcttcttt atcttttacc
     3841 cagcccgttt tcatttcccc tgatggagca aagtaatacc attgcccctt atattgaagc
     3901 caacctgtct tcatagagcc atcaacatcc aaataatacc actgctcttt atcttgaatc
     3961 caaccaattt ccatctggtt ttctttgtta aaataatacc agattccagc gattttcttc
     4021 caatttttag cagcaacacc agagtctgtc aaatagaacc aacgattgtt ccattttttc
     4081 cattgattct gtaataagat acccgtttgg ttaaagtaat accattcacc cttaatttca
     4141 ttccaaccga cagcatattc tcctgtagaa tcaggcgctt gataccacca gtttccatat
     4201 gaactcttat gccaaccagc ttgaaaactt ggaataggct tgtaggaagt tgaaatgttt
     4261 actaaaccgt cttgtcgaat atcaaaaact gttgcatcat agtctttgct ggctgcgttg
     4321 attctctcaa ttcctcgttc tttgagccaa ttaacatact cactatcaac accatttttc
     4381 caaggtagac tatccgaagt ttgaacaatc aaactcggac tcaaattttt aatgaaatcc
     4441 ttggtatttg atttgttggt atcatggtga tgattaaact tcatcaaatc aacttttcca
     4501 atgagaggac catacttgtc ttctgctcca tgaacattat ctaagtcgcc cccaaggtaa
     4561 attttcttgc cattgacttt taccacacta atcaaggaat tggaattatc atcccaaatt
     4621 ttctttaatt cacctgatga atcggtttca ttttcatagt tatagagttg aatatccatg
     4681 tccccaaact gaaaatgagc atctccctgt gtgatgtttt gaataactga aacacctttt
     4741 tctgaagcag tctgtaaaac cttatcataa ccgtacagat tatcccatag acgttcagaa
     4801 ttagtaatac gattatcact atatttttta agatagactc ggtcaactgg ataggtagac
     4861 agtaattcat caacatttcc aatatggtca ctgtgggtat gggtcaccaa aataaaatca
     4921 agtttttgga cacccaattc cttcaaacga cgaaagacac ggtctgttag aacatgctta
     4981 taagacgttt caattccttc tctccatgga tagcgagaat cacttccatc tgggaaatca
     5041 taatcttctc ctgtatccac catggcaaaa tgtccattgc tttcaagaat aatcgcatca
     5101 ctgccacctt cttgaacatt gataaagtgg attttatttc ctgaactttc ttgagcctga
     5161 acattcccat accatgacaa acctaaaaaa gcgcctacaa gtgctaaact agttaatttc
     5221 tttttcattc ttactttctc aatctctcca gggtttcctt aaaaatttct gggatatctg
     5281 ctttaaattc caaggtctta cctgttctcg gatgagtaaa acctaaagtc ttggcatgaa
     5341 gaaattgtcc atgtcctttc aaagtcttgc gaggaccata gacctcatca ccagcgactg
     5401 gatggtcgat ataagccatg tggacacgga tttgatgagt gcgccctgtc tccagttgca
     5461 actctactaa gctataatcg ccaaagcgtt ccaagacatg aaaacgcgtc actgcaggct
     5521 tccctttagc aattacagcc tgtttcttac ggtctttttc actccggcca atcggcgctt
     5581 caattacacc acgatcatta ggcagatttc catgaacaat cgcccaatat ttgcggagag
     5641 actttttatc cttgagttct tgggcaagtg ctagatgcgc atcatcgttt ttagcaatca
     5701 tgagaagacc tgacgtatcc ttatcaatac ggtgaacaat tcccggacgc agaaccccat
     5761 tgataccaga caagtcctta atatgataca tgagggcatt gactagagtt ccactagtat
     5821 gaccagcact cggatgcaca accattccct gaggtttgtt aacgacagcc acatcctcat
     5881 cttggtagac tatttctagc ggaagatcct cagccacata ctctaatacc tctggttctg
     5941 gcacatggta agtgacgaca tcaccctctt ggactgtgta tttagctttc ttgacttgac
     6001 cattgaccaa gacctggcct gatttaattt gttcattcgc aagactgcgt gataattctg
     6061 tcaaatctga caaagcctta tccaaacgca gaccaccagt ttcaatttta atttccattt
     6121 atttcctctt ttagcattgc aatcaataaa ataatcactc caaccgtcag atagctatct
     6181 gccacattga aaattgcaaa gttgataaag tcaaggtgga acatatccac aacaaagccc
     6241 tgactggccc tgtcaataaa gtttccaaga ccacccgcga ttatcaaagt caaacccaag
     6301 accatccaga atgagtcctc catgtgttta tgtaaatacc aaatggcacc tatcacgaca
     6361 accagagtaa tgacagcgaa taacagctgc tgatcttgta agatagaaaa ggctgcacct
     6421 cgattttgca ggtaggtcaa gctaacgaaa ttgggaatcc aggagcgcac ttcacccagt
     6481 ggaatctgct ggacgatata ggatttgacc aactgatcca gcccaattaa aagcagtaca
     6541 atgactgcca ctattgctct ttttttcatg atttcctctt ttgatcaaaa tattcttgca
     6601 tgacttctac gaagagagtc ccagcttgac taagctccac ttcttcacgt ttaacataga
     6661 ccatgcggtt atctaggtta tccttgagac gaataactgt aatgccatta acactgtcac
     6721 tatctaaaaa tccagaacct gtcgcatagg cgtccgtccg ctccaaaata ccattcaagg
     6781 tggcacggtc tgtcacatta aacatctgtg agctagcgct ggtatcgaca aagttctctg
     6841 aataataaag gtactcgtct ttctcttgag tgaaacgaac cgttggtaaa tccgctaaat
     6901 cctccatgac taattcctct ttctgggcta aaggatgacc ctcacagaga taaatatggg
     6961 tatggaaagg aatcaattcg atgacctcca gacctaactt ttcaacccgt tgcataatcc
     7021 cctttttatt ttgattgttg aggtagataa tcccaatctc actatgccct tgcgccactt
     7081 catctaatat ttgaacagta gttgattcaa aaatacggaa gttcttatag tcaggatagc
     7141 gctctgaaaa ggccgtaata gttggtggta agaagtcata gtgctggcta gcaacggaaa
     7201 attcatcttt ttcttcttca ggattggcat actgattttg aaaaatatca aatcctttaa
     7261 ccaattcttg cgctttttca taaaattcca tcccacgacg ggtcaagaaa gtccctgagc
     7321 tggtccgacg gaaaatctta aagcccaact ctttttccaa atcacgaaca gaaatagaca
     7381 gactcggctg actaacatac atcttttcag cagcttcacg aaaagtacca ctattggcaa
     7441 tagccacaac atagcgtaac tgttgaatgt tcatcttcta cccccaactt ctttatcttt
     7501 tcattatacc atattttaga agttttccaa aaaggaaaaa agaacatcct attcttctta
     7561 actatcttca ctatctgcct ttctcacgcc aatcttattt tcaaaatcaa ttcaaaaaaa
     7621 taagtggcta cacaccactt cagtatcgga aagaaaaacg ttgactattt gtgaaaaaag
     7681 aaaatgccgg aaaattccga cattttttta gtaagctaac ttcctgaaaa taggagtaac
     7741 cacacatccc agaaggcagt gatattgatg agaatatgaa ctagtattgg atagtagaga
     7801 tttttagtca tgcgatacaa tagagctaaa ataagacctc cactagcata aatgaaaaaa
     7861 gcaagaggag ttaaagcaaa attgatatga atataaccga aaataatagc agaaagcaaa
     7921 acatctccgt accaaggtga gtttttgaaa aaggttgtca taagcacacc tcgataaatc
     7981 aattcctcag caataggggc gatgaagcaa acgatgagca agaaataagg gaactcctgt
     8041 ctccccatca tttctaccgt ttcattcaaa gaaatctgat ttgaagacag ggatatgaaa
     8101 tacgaaaaga ggaagtcaga catatatgaa atgatgtagc ccagtaaaag gtagatgaag
     8161 tacctcagct gccacttgaa atgaaaaatt ttctttcctg caaaaaccag tagatagatg
     8221 accgctaaga aaagaactcc gctctccatc aaaagcagaa tctgaaaaaa ttcacgactt
     8281 gctggtagat agggctttgc gaggtgattg aaaactctcc aaaaccaagt tgatttgtaa
     8341 aaaattaagg acaatgctag taaaatttga atagcccgtt ttttcatatt aaattctctg
     8401 ctttctccac ttgtttcttc atattactaa taaattttac ttaaaatctc gcagcacttc
     8461 ctttgcaaag atgattgcct cctccaatat atcctaaatc ataggtgcct ctgggacaaa
     8521 atccatgaac cggcagagtt aatactggtt ctatttccca atcgtaccta ccattaggat
     8581 ttttaccata tggatctgct ccaccttgta tcagctctaa ttcttcattt gttagattta
     8641 tattttttgt cattaaaatc atgatatatt tcctccatta ttcttcagat tagttgagta
     8701 atctgatact catacctact tacaaaaaaa ctattatatt aagttggttt tttaatttgt
     8761 ctagttgcaa cattgacaaa catagtatag catatctttg ccaaatatcc tcttcaaatc
     8821 atgaattgtc atcaaaacat cttaaactat aaaatcaatt agtctcaagc tttctatcaa
     8881 tttcttctcc aaaatatgct ataataatag caaaagataa agaaggaaga cctatgatta
     8941 aactactagc cttggatatg gatggaaccc tcctcaatga agccaaggaa atcccacagg
     9001 ctcacatcgc tgctattcac caagccattg aaaaaggtgt caaactggtt ctctgtacgg
     9061 gtcgccccct tttcggtgtc ctcccctact acaaaaaact gggactcgac ctccagaatg
     9121 agtatgtgat tgttaacaac ggttgttcaa ctcaccagac tagcgactgg ggcttggttg
     9181 actggcaaga acttagtcca gctgacatcg aatacctcta tgaccttgct gaaaagagtg
     9241 atgttcagtt gacacttttt gacgagtcac attattttgt tctcggtggc aaacccaatc
     9301 aagttattga aaatgatgct aaactagtat tttcagacct gactgaaatt tctcttgaag
     9361 aagcgactag tggaaagtta cggatgttcc aaggtatgtt tttaggaaca aaagaacaaa
     9421 cagacgattt tgagcagcgt tttgctgaag agctttgcca acgattcagt ggagttcgtt
     9481 cgcagcctgt catttatgaa gcaatgccgc ttggaacgac aaaggctact gctctttcac
     9541 gactagctga gattttgaag attgattcct cagagattat ggccatgggc gatgctaata
     9601 acgatatcga aatgctccag tttgcagggc ttgggattgc aatgggaaat gccagcgatt
     9661 atgtcaaatc tcttgcggat gccgttacct caagcaacga agaagacggc gttgcgcgtg
     9721 ctattgagaa atatattcta taaaaaagaa aagcaaatag acagaagtta ctgctatttg
     9781 cttttttgct aatattttaa aatacggact aatcaataga caagaatagc gaatcataaa
     9841 aatcgattta ctagatgcca tagtatctta tagttgctaa taagaagtta gtctagcaga
     9901 atgaatctct catttctccc acactaatct gtaatttgtc tatacatttc tggtcttcta
     9961 tctcgaaaca agccccagtt taggcgttca cttgctccct tgtctaggtc ataagtagct
    10021 aacagaacag cttcttcttg tctttcagct cgttctagaa tagctcctgt ttcatccgtc
    10081 ataaaggagg aaccgtagaa gtcaagactg gaactctgtc cgccattttc ctcactagga
    10141 gtaacctcct ctaaaccata acgattggct gcgatgactg gaacaatatt cgctgctgcg
    10201 tgcccttgca tagtacgttg ccagtgacca caactatctg tatccaaaat cggctctgaa
    10261 ccgatggctg ttggataaaa gagcaattct gccccattca gagcaagaca gcgggctgtt
    10321 tcggggaacc attgatccca acagataccg ataccaatct tagcatagcg agtattccag
    10381 accttgaaac cagtgttacc aggcgtgaaa tagaattttt cttgataata atggtcatct
    10441 ggtatgtggg tctttcgata aacgcccaac acttccccat ctgcatcaat gacggcaata
    10501 gagttataca agacattacc atctttttca tagaaactga ttggtaaaac aacttgtagt
    10561 tccttagcaa tcaccttaaa atgctgaatg gcagtatttt ccgctacaga ttgggcatac
    10621 tggtagtagt catactgacg ttcctgacag aaatagggat gttcaaacaa ctcgggcaag
    10681 agaataattt gggctccttg ctcagcagcc tgacgtacta aacgctctgc ggtttggata
    10741 tttgttgcca catccttagc gcattgcatc tgaatggttg caactcttac atttctcatc
    10801 tttttctcct attctggaat ttgttgggtg atacagtgga tattgccacc acctaagaga
    10861 atatctctgg ctggtattcc gacaacttta cggtctggga aacacttgct gaggatatct
    10921 aaggccactt ggtcgtttac atcctcaaac tgtggaacca agacagcctt gttggcgata
    10981 taaaagttta cgtaggaagc tgctagtcgt tcacctgcgt atcgcttttc ttctccttct
    11041 tcatagatgt agcctggcaa atcttcttct gtcacaactt gtcgaactgc agggataggc
    11101 aatttatgaa tggtgaagtg acaacctttt gcatctgttt cctgttctaa gagttcgaga
    11161 tctgcttttg acatggcata ctggggatca ttttcgtcat ctgtccaagc caaaacaagc
    11221 tcagcaggac caacaaaggc agcaacatta tcgacgtgtt cattggtttc atcctgataa
    11281 ataccataag gaagccaaat aactttttca gcaccaagac tttctaataa tgtgttttca
    11341 atctcctctt tagtcaggtt aggattgcga ccaggactaa gcaagcaact ttcagttacg
    11401 agaatagttc cttgaccatc gctatggatt gcgcctcctt ccagtacaaa aggtttagca
    11461 tcatagacag gccttcccaa ggcctcagca aaacgactgg ctacttggtc atcctcttca
    11521 taatcttgat aaagaccatc ataggtgcct ccccaagcat tgaaggccca atccacggct
    11581 aatttcttac ctttatcatt gacgagaatg gttgggccag tatcacgcgc ccaggcatca
    11641 ttggtgggaa tgtctaaata aacaaccttg tctccaagat aggattgggc ttcagataga
    11701 taggcctgct ccaccaaaag atagactctt tccccttctg ctatggtctc gatgatctga
    11761 gtaaatgctc ttttagcagc ctttccttga aaaggccatg atcctggtcg agtcggccat
    11821 atcatgaggg taccatgatg gggttcgtac tctgctggca tgtgatagcc taattttttt
    11881 ggactgtcca tcatgataat ctccctttaa agtcttgata gccaaaagct ttgagtaagc
    11941 tacagtctcc ctgttcgtcc atgagataga gacttggcaa tccaatacca ttaaaggtat
    12001 tatttttgac aaaagaataa atggccatgt cttgaaaata aagtctgtct ccgatttgga
    12061 ctggattttc aaaactataa tcaccaatca catcgcccgt cagacaggta ttagaagaaa
    12121 gtctgtaggt atgggctttt tcctgtgcct caaagccatt tctcaaagat ggacgatagg
    12181 gcatctcaag tacatcaggc atatggcagg tcgcagaggc gtctaaaacc aagatttcca
    12241 taccgttttc tacaatatct aatacctcag ttgctaaata acccgcatta agcgcaatgg
    12301 cttcaccagg ctcgatatag atttcaagat tgtaagtttt tcggatacgc ttgatttctg
    12361 aaatcagcaa atccacatcg taaccttctc ttgtaatatg atgaccacca cccatattga
    12421 gccattttac ctcatgtaag tagggaccaa actgttcttc tactgctttc aaagttgttt
    12481 gtaaatcatc tactccctgc tcgcaaaggg tatgaaaatg aagtccgtca accaaatcta
    12541 gcaaatcact cggaatcttg tctatagtaa ctccaaagcg agaacctggt gcacaagggt
    12601 catagagcgc gtgatctcct tgagttgaac actgagggtt gaggcgcaaa ccaacactga
    12661 caccagcctc tcgacaacgc ggaccgtgtt tacgcaactg tctctctgag ttaaagacga
    12721 tatggtccat tatctctagc aattcctcca agtctgcatc cttgaaagca ggcgcaaata
    12781 catggacttc accaggaaat tcttcccttg ccaatttggc ctcatagagt ccactagctg
    12841 tcgtacctga tagatactgg ctaatcaagg gataagtttt gtagagggaa tatgccttct
    12901 gggcaagcaa gaccttgcaa ccggcctctt cttgtacata ttgtagaatg cggcaattag
    12961 cttctaactt ggccaagtca ataacatagg ctggtgttgg tacttgttct aacttcatta
    13021 gtccaccatt tgtggatttt caaccacaac ccatggcaaa ccatactcat tcaaagcttc
    13081 catgaatgga tctggatcta actcctcaag gttatacact ccagcttgtt tccaagttcc
    13141 gttcatgact aattttgtcc caatcatggc tggaacgcct gtcgtgtatg aaattgcttg
    13201 tgacccgact tctgcatagc actcttgatg gtcgcaaaca ttgtagatgt agatagtctt
    13261 ttcaacgcca tctttgacac ctgtaaagat acatccaata ttggtttttc cgactgtacg
    13321 tggcccaaga ctggcaggat ctggaagcaa ggctttcaaa aattgaattg gaacaatttc
    13381 ttggccgtta aagttaatgg tatccgtacg aaggagtcca acattttcaa gacatttcat
    13441 gtgcgtcaag taagattgac caaaagtcat aaagaaacga atgcgtttga cacctggaat
    13501 gttcttggcc aatgattcga tttcttcatg gtgaaggaga tacatatctt tttgtccaac
    13561 ttgagggaaa tcatactcac gcttgataga catagcttcg acttcgaccc atttcccatc
    13621 ttcccagtaa gaacctggag cagaaacctc acggagatta atttctggat taaagttggt
    13681 tgcaaatgga taaccgtggt caccgccatt acagtctaaa atgtcgatat aatggatttc
    13741 atcaaaatag tgtttgaggg cataagctga aaagacacta gttacacctg ggtcaaaacc
    13801 agaaccaaga agagcagtca agcctgcttc tttgaatttc tcttgataag cccactgcca
    13861 tgagtagtca aagtaggctg taaaaccaag ttccttacaa cgtttttcgt agatagcacg
    13921 ccactcaggg tcttctgtgt cttctgcttc gtagttggct gtatcgatat agtgaacacc
    13981 tgttgccaaa caagcatcca taatggttaa atcttgataa ggcagagcta cattcaaaac
    14041 ggcttctggt ttgtagcttt caatcagggc aatcacttct tcaaccttgt cagcatcaag
    14101 tgctgcagtt tcaattttag tacttgtttt gccttctagc ttcgctttca agtcatcgca
    14161 ttttgacttg gtacggctag caatcataat ctctgtaaat gtttcgctat cttgacaaat
    14221 ctttgaaata gcaacttggg caacgccccc acaaccaata actagtaaac gactcatttt
    14281 tttccttcct cttcttctaa aatgtcctca acatacttgg gcaacataaa ggatcccacg
    14341 tgtaagtttg cagtgtagta ttctgtgaaa agctggcgtt ttttccaacc ttccttgtca
    14401 aaatctttga cagggtggta ttttttcgat gcaaatccaa acaaccaata gccagctggg
    14461 ctagttggaa tatgggcctg ataaacccga ctgattggaa aggattgatt gaccttgcgg
    14521 tgcatgcttc ggcaggccga ctcatcctcg tcaaagaagg gactcccatg ctggtaaatc
    14581 atgatgccgt cttccttcag agctcgataa ctattgccgt agaattcctt ggtaaagagt
    14641 ccttccgtat ggccaaatgg atctgtcgca tcgttgatga taatatcgta atcatcttcg
    14701 cagtttcgca aaaagcgtag cccattttgg tagtaaatgg taacacgagg atcatctagc
    14761 cctgcagcaa agtctgggaa atactcacga cagacctcga ccaacatctc atccggttcc
    14821 acgatatcga tttgttccag ttcaggatag agtgttaata cttgggcaac accgccgtca
    14881 ccacccccaa taaccaatac tttctttgga tttgggtgga cagccatggg aacgtgaacg
    14941 gtcatttcat tgtagacgaa atcatccgca tctgagaaca agacatggcc atttaaaatc
    15001 agtattttcc caaaagctgg cgtatccaag acttcgatat cctgccattc actttttcca
    15061 gcgtaaagtt gcttggctgt tctcagagac aatttgacat ctggagtatg aacttcagaa
    15121 aaccataaat ccatctattt ctccttatat tatatttagc gcagttagct actgccaaag
    15181 cccaagtggt atacttggaa taagccactg tggattagtt tattccctcc aatcgcttga
    15241 cgatttccga aaggctctaa ccacagtttt ttgtttcaat tggtaatgag tttgataacg
    15301 catagacgtt ttatctcgtc taaggtaaca agacaaaaaa ttcgtggata accaagtaga
    15361 cttgaaatac tacatctgga ggtactccca tgctttatgt gggcattgat gtcgctaaaa
    15421 ataaacacga tgttacagcc ttgaatgttc caggaaaaac tgttcttaaa ccactcactt
    15481 tttcaaataa taaagctggt tttgaactct tagatctgtc tcttcgacaa ctcaaccaag
    15541 actgtctcat cgctcttgaa aataccggac attatgcctt taatctactg aacttcctgc
    15601 atgaacaagg atataaagtt tacacctgca atcctttgct catcaaggaa tttgccaaat
    15661 cattatcact tcgcaagact aaaacggata agaaagacgc tcatggcatc gctcttaaac
    15721 ttctttctga ccccaatcgt gaacaatttc aacacgataa tcggcaagta gaactaaaaa
    15781 tactggctag acatattcat cgtctcaaga aaaacagtct gattggaaag tacaatacac
    15841 tcgttgtctt gatatcatct ttcctgagtt ggataaaatc gttggaaagc attcagaata
    15901 tacctaccaa ctcttgacac gctaccctaa tcctcagaaa aggattgagg caggatttga
    15961 taagctgata gaaattaagc gattgaccgc ttctaattca agggcttttt gccgtgctct
    16021 aaaatcatcg ccaaatcatc aaattgaaat aagaaatagt ttagataaaa ctattgactt
    16081 ttcttatagt ttgtctttct cttaataacg ttgatatgat tgacctctgg atcttccgtc
    16141 ccttggaggg agcaaccacg ttccttggcg aattggatat agtctacaat ttctcgtgta
    16201 atgcgttcac caggagccaa gataggaatc cctggaggat agcacatgac aaattctcca
    16261 cagacctgtc caacagactc atctaaggtc aaactttttc tctctgaata gaaggcttct
    16321 tgtggagaca gcaccaactc gggctgaata tattctccag ctattaagtc cttcccatct
    16381 cgtgaataga gtctcttaat atcagccaga gcaccaacca agcgctcgat gtcttggatg
    16441 cggtcgccga tggaaatata ggccaagata ttgccgatat caccaaactc gatctgaatg
    16501 tcgtattcgt ctcgcaagag gtcataaacc tcgatacctg ttaagcctat tccctgagtg
    16561 taaactgaca acttggttac atcaaaatca cagaccgaca caccatctat taactctttt
    16621 gagtaagcat agtaaccgcc aatggcattg atttcatgac gagcgtactc ggatagctca
    16681 atgacttcct caaacgactc tttaccacga agggccaagt tgcgacgtga aatatccaaa
    16741 ctagccatca ataagtaaga ggcagatgta gactgggtca ggtttataat ctgacgaacg
    16801 tactcgggat tcatctgctc cccgattaaa agaagcgaac tttgtgtcaa actcccacca
    16861 gacttatgca tggaaactgc tgccatatca gctcctgcat ccatagcaga aattggaagt
    16921 ttaccagtga aatgcaaatg cgctccatgg gcttcatcta ctaaaaccat catgccagct
    16981 tcatgagcca tttctgtcaa cccctttagg tctgaacaga tgccgtagta agtaggattg
    17041 ttgattagga tagccttagc atctggatgg tcctttatgg cctgtgctac tcggtcattt
    17101 tcaagaccta aagcgatacc aatcttagga tctacactca tctcgatata gatgggaatg
    17161 gcaccacata gaaccaacgc attgatagca gatttatgga catttcgtgg cagaataatc
    17221 ttatctcctg ccttgcaggt tgccagaatc atagtctgca ccgatgaagt tgttccacca
    17281 atcattagaa aggcatggct agctccaaaa gcatctgcag ccagctcctc tgcatcacga
    17341 ataatcgaaa taggatggcc taaattatcc aagggtttca tcgaattgac atcaatgcct
    17401 acacattttt ctcctaagag ttcgacaagt tctggatttc cccgtccacg cttgtgacct
    17461 ggaacatcaa agggaacaat ccttttcttg cgtaacttca ccaaggcctc ataaattggg
    17521 gcttggtttt gatctacctc tttcaaaaca tactcctttc aatattttta ggaccttatg
    17581 aaaactaagg aactaaaggt tgactcatga aaaaagagca ggttttcacc tgctctgcaa
    17641 tcttctgacg tgtttatttt ggtttctgtt gagtatgtct gttcccgatg tttcctaact
    17701 ctctagtagc aaatattacg tactttattg atcgtttcac aagatgacgt gtgctttcac
    17761 cacactaaaa atttatgaat taggacaagt gtcctaacat caacttataa aagtaggctt
    17821 ttaaccctat caataatgtg gcttttcaac cacgcttcgg cattcaaccc tgcctgtccg
    17881 taggcatttt ttactcgggt ttatatttgc tagaaaacat catctcattt tctaagcttt
    17941 attactatat catgttttta agaacttgta aagtattttt tgataaaaaa caaaaatata
    18001 atagattgaa actagaatag tacacttctg cttctaaaac attattagaa atagatttta
    18061 ctgtcctgat cgatttgttc tgttcttgtt tcattttact atatgttcgt aaatgaaagt
    18121 tctataatga agttagccac ccagccctcc taaaaattag atggttcaac tagctgatag
    18181 ctcttgtagg cataagaaaa cacctctgtg ttatacttgt tgttcaacca caaacacaag
    18241 aaaggcacag aaatgcaaga caattatact acaaaaggta aacatttgac aatcgatagc
    18301 cgtcgcttaa tcgaaagatg gaaaaaagaa ggaaaatcaa atagagaagt tgcctctcta
    18361 cttggaaaag ctcctcaaac tatccacact gaaatcaagc gtgggacagt ccga
//
LOCUS       DAVBOD010000041        18303 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 640-05
            SAMEA1012484-rid20186543.denovo.041, whole genome shotgun sequence.
ACCESSION   DAVBOD010000041 DAVBOD010000000
VERSION     DAVBOD010000041.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012484
            Sequence Read Archive: ERR059358
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 18303)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18303)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979948.1
            Genome Coverage       :: 595x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:03:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,266
            CDSs (total)                      :: 2,219
            Genes (coding)                    :: 2,091
            CDSs (with protein)               :: 2,091
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 71 of 128
            Pseudo Genes (incomplete)         :: 50 of 128
            Pseudo Genes (internal stop)      :: 33 of 128
            Pseudo Genes (multiple problems)  :: 22 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18303
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012484-rid20186543.denovo.041"
                     /strain="NIG 640-05"
                     /db_xref="taxon:1313"
     gene            161..475
                     /locus_tag="VQ862_001488"
                     /pseudo
     CDS             161..475
                     /locus_tag="VQ862_001488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000996568.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GDP-mannose 4,6-dehydratase"
     gene            652..1311
                     /locus_tag="VQ862_001489"
     CDS             652..1311
                     /locus_tag="VQ862_001489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000793810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1868 domain-containing protein"
                     /protein_id="HET3115815.1"
                     /translation="MKNLTKIKFKENGEFNHFSGNTVVANLYTKQDLMEVVDIIQSRY
                     RELPFIDKFTLTPRNSIHMTVIELLCHENRETEFWSSNLPLDTPLQEIHDYFAKQLEI
                     FPLLDEEIHMRITEMGKQNILVEPADEASAKRLEEIRTYVSEKAGVCFPNHDRYQFHI
                     SIGYLRIPLTEEEEEEFTKVRAELTEILLEKIPTITVNRIDYTVFEDMRQFVPYHEKF
                     K"
     gene            1336..2403
                     /locus_tag="VQ862_001490"
     CDS             1336..2403
                     /locus_tag="VQ862_001490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HET3115816.1"
                     /translation="MKKMKVWSTVLATGVALTTLAACSGGSNSTTASSSEEKADKSQE
                     LVIYSNSVSNGRGDWLTAKAKEAGFNIKMVDIAGAQLADRVIAEKNNAVADMVFGIGA
                     VDSNKIRDQKLLVQYKPKWLDKIDQSLSDKDNYYNPVIVQPLVLIGAPDVKEMPKDWT
                     ELGSKYKGKYSIYGLQGGTGRAILASILVRYLDEKGDLGVSEKGWEVAKEYFANAYTL
                     QKGESSVVKALDKESPIQYGMIWGSGALIGQKEQNVEFKVMTPEIGVPFVTEQTMVLS
                     TSKKQALAKEFIDWFGQSEIQVEYSKKFGSIPANKDALKELPEDTKKFVDQVKPQNID
                     WEAVGKHLDEWVEKAELEYVQ"
     gene            2506..3516
                     /locus_tag="VQ862_001491"
     CDS             2506..3516
                     /locus_tag="VQ862_001491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3115817.1"
                     /translation="MIKFDNIQIKYGDFVAIDNLNLDIHEGEFFTFLGPSGCGKSTTL
                     RALVGFLDPSSGSIEVNGTDVTHLEPEKRGIGIVFQSYALFPTMTVFDNIAFGLKVKK
                     VAPDVIKAKVSAVAAKIKISDQQLQRNVSELSGGQQQRVALARALVLEPKILCLDEPL
                     SNLDAKLRVDLRKELKRLQKELGITTLYVTHDQEEALTLSDRIAVFNNGYIEQVGTPV
                     EIYHNSQTEFVCDFIGDINVLTDETVHEVLLKNTSVFLEDKKGYIRLEKVRFNRETEQ
                     DFILKGTIIDVEFSGVTIHYTIKVSESQILNVTSIDSQAAIRSVGESVELFITPSDVL
                     QF"
     gene            3528..5219
                     /locus_tag="VQ862_001492"
     CDS             3528..5219
                     /locus_tag="VQ862_001492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HET3115818.1"
                     /translation="MRHKLNLKDWLIRLGLIWFLVTFIIYPNFDLVVNVFVKGGEFSL
                     DAVHRVLKSQRALQSIMNSFKLAFSLIITVNVVGILCVLFTEYFDIKGAKILKLGYMT
                     SLIYGGVVLATGYKFVYGPYGLITKFLQNVIPSLDSNWFIGYGAVLFIMTFSGTANHT
                     LFLTNTIRSVDYHTIEAARNMGAKPFTVFRKVVLPTLIPTLFALTIMVFLSGLSAVAA
                     PMIVGGKEFQTINPMIITFAGMGNSRDLAALLAIILGIATTILLTIMNKIEKGGNYIS
                     ISKTKAPLKKQKIASKPWNIIAHIVAYGLFTVFMLPLIFIVLYSFTDPVAIQTGNLTL
                     SNFTLENYRLFFSNSAAFSPFLVSFIYSIIAATTATILAVVFARVVRKHKSRFDFLFE
                     YGALLPWLLPSTLLAVSLLFTFNQPQFLVLNQILVGSLVILLIAYIVVKIPFSYRMVR
                     AILFSVDDEMEDAARSMGASPFYTMMKVIIPFILPVVLSVIALNFNSLLTDFDLSVFL
                     YHPLAQPLGITIRSAGDETATSNAQALVFVYTIVLMIISGTVLYFTQRPGRKVRK"
     gene            5222..5932
                     /locus_tag="VQ862_001493"
     CDS             5222..5932
                     /locus_tag="VQ862_001493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000127555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MgtC/SapB family protein"
                     /protein_id="HET3115819.1"
                     /translation="MTATSLGLSNIEIVVRIVLSVVIGSIIGLERGSKSQPAGIRTYS
                     IVCLAACLIMMTNEYVSYKFGTGDPTRLGAQVISGVGFLGAGTILITDKKKITGLTTA
                     AGIWASAGIGLAIGVGFYEGALLVAISVWGVISMFQPLKKYLQNRSKMIELYIVVKST
                     EAYNRVLVYCAENGIRMTDSRTAFGDVNSDRIEYFDVPDKKIASFITLELSGRFEHLR
                     LMEEIANIVGVIYVEEIS"
     gene            6028..6219
                     /locus_tag="VQ862_001494"
     CDS             6028..6219
                     /locus_tag="VQ862_001494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000656293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3115820.1"
                     /translation="MKDYKINFDLGKIEYFDNNCLIQVYKFISFYDICEMVFAFHLPP
                     DELITNVIFKEKINSMLKC"
     gene            6504..7505
                     /locus_tag="VQ862_001495"
     CDS             6504..7505
                     /locus_tag="VQ862_001495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000789954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HET3115821.1"
                     /translation="MKNINGKKVTIYDIARLSGFSPKTVSRVINGGVNVKEETYQAIQ
                     KVIEELSYIPNAYAKNLTKKEAINILISVKKIDSFPLIWFHTLLDKVLRTCKEFGVNA
                     IVEYFGEEDTISNSIISSTGSLVDGVIVFYESVDDIRIQYLKKNHMPFLVFGESQTSG
                     VVYVSNNNFQATYDMMKAVTEEKFKNMWLLMGGESHVNKDRERGVRSFLNDKNYFMDL
                     KVIYGLSTIDSVYSYAMQHLTTQNYPDIIFVSGDEKVQGLIRACYEKGILIPDDISII
                     GFDNIPISQYYTPALSTIAPNYVKLAKEMIEGVLAIIKGESVTSVEVSPKFVRRQSF"
     gene            8113..8187
                     /locus_tag="VQ862_001496"
                     /pseudo
     CDS             8113..8187
                     /locus_tag="VQ862_001496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829418.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            8646..10007
                     /gene="trpE"
                     /locus_tag="VQ862_001497"
     CDS             8646..10007
                     /gene="trpE"
                     /locus_tag="VQ862_001497"
                     /EC_number="4.1.3.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anthranilate synthase component I"
                     /protein_id="HET3115822.1"
                     /translation="MERIIHGDVLSPILAYMRLKGQHKVILESIPRDKETARFSILAY
                     NPVFEIKFENGVLYQNGQVIDRDPLDFLYEVIHKSQHHSELPFGGGAIGFVGYDMISL
                     YEEIGQIPEDTIGTPDMHFFVYESYMVFDHKKEKIHVIEDALYSERSQEALEKSLNQV
                     LEELRIPAPNEFEDLDLSPLDFKPHIAPHKFEGMVETARDLIRNGDMFQCVLSQRFSA
                     EVTGNPFDFYRNLRVTNPSNYLYFYDFGDYQIIGASPESLVSVKNGIVTTNPIAGTRP
                     RGATDEEDKALATDLLSDEKETAEHRMLVDLGRNDIGRISETTSVQVTKYMEVELFRY
                     VMHLTSVVKGRLLPELTAMDALKATLPAGTVSGAPKIRAMRRIYELETEKRGVYAGAI
                     GYLSATGDMDLAIAIRTMILKNQRAYVQAGAGIVYDSIAQNEYQETINKAKSMTRIGE
                     LRP"
     gene            10004..10570
                     /locus_tag="VQ862_001498"
     CDS             10004..10570
                     /locus_tag="VQ862_001498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate/anthranilate synthase
                     component II"
                     /protein_id="HET3115823.1"
                     /translation="MILLIDNYDSFTYNLAQYIGNFAEVQVLRNDDSKLYEEAEKADG
                     LVFSPGPGWPVDAGKMEDMIRDFAGKKPILGICLGHQAIAEVFGGKLGLAPKVMHGKQ
                     SNINFEAPSVLYQGIEDDRAVMRYHSILIEEMPEDFEVTARSTDDQAIMGIQHKNLPI
                     YGFQYHPESIGTPDGLSSIRNFIEKVVK"
     gene            10581..11585
                     /gene="trpD"
                     /locus_tag="VQ862_001499"
     CDS             10581..11585
                     /gene="trpD"
                     /locus_tag="VQ862_001499"
                     /EC_number="2.4.2.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anthranilate phosphoribosyltransferase"
                     /protein_id="HET3115824.1"
                     /translation="MKEIIEKLAKFENLSGVEMTDVIERIVTGRVTEAQIASLLLALK
                     MKGETPEERTAIARVMRGHAQHIPTEIHDAMDNCGTGGDKSFSFNISTTAAFVLAGGG
                     IHMAKHGNRSISSKSGSADVLEALGINLDLKPAELGKVFDKTGIVFLFAKNMHPAMKY
                     IMPARLELGIPTIMNLTGPLIHPMALETQLLGISRPELLESTAQVLKNMGRKRAIVVA
                     GPEGLDEAGLNGTTKIALLENGEISLSSFTPEDLGMEGYAMEDIRGGNAQENAEILLS
                     VLKNEASPFLETTVLNAGLGFYANGKIDSIKEGVALARQVIARGKALEKLRLLQEYQK
                     "
     gene            11582..12349
                     /gene="trpC"
                     /locus_tag="VQ862_001500"
     CDS             11582..12349
                     /gene="trpC"
                     /locus_tag="VQ862_001500"
                     /EC_number="4.1.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011227478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="indole-3-glycerol phosphate synthase TrpC"
                     /protein_id="HET3115825.1"
                     /translation="MSQEFLARILEQKAREVEQMKLEQIQPLRQTYRLAEFLKNHQDR
                     LQVIAEVKKASPSLGDINLDVDIVQQAQTYEENGAVMISVLTDEVFFKGHLDYLREIS
                     SQVEIPTLNKDFIIDEKQIIRARNAGATVILLIVAALSEERLKELYDYATELGLEVLV
                     ETHNLAELEVAHRLGAEIIGVNNRNLTTFEVDLQTSVDLAPYFEEGRYYISESAIFTG
                     QDAERLAPYFNGILVGTALMQAENVAQRIKELQIDKG"
     gene            12336..12935
                     /locus_tag="VQ862_001501"
     CDS             12336..12935
                     /locus_tag="VQ862_001501"
                     /EC_number="5.3.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylanthranilate isomerase"
                     /protein_id="HET3115826.1"
                     /translation="MTKVKICGLSTKEAVETAVSAGADYIGFVFAPSKRQVTLEEAAV
                     LAKLIPADVKKVGVFVSPSRVELLEAIDKVGLDLVQVHGQVADDLFENLPCASIQAVQ
                     VDGNGHVPNSQADYLLFDAPVAGSGQPFDWGQLDTTGLAQPFFIAGGLNEDNVVKAIQ
                     HFTPYAVDVSSGVETDGQKDHEKIRRFIERVKHGISGTK"
     gene            12913..14136
                     /gene="trpB"
                     /locus_tag="VQ862_001502"
     CDS             12913..14136
                     /gene="trpB"
                     /locus_tag="VQ862_001502"
                     /EC_number="4.2.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan synthase subunit beta"
                     /protein_id="HET3115827.1"
                     /translation="MAYQEPNKDGFYGKFGGRFVPETLMTAVLELEKAYRESQADPSF
                     QEELNQLLRQYVGRETPLYYAKNLTQHIGGAKIYLKREDLNHTGAHKINNALGQVWLA
                     KRMGKKKIIAETGAGQHGVATATAAALFNMECTIYMGEEDVKRQALNVFRMELLGAKV
                     EAVTDGSRVLKDAVNAALRSWVANIDDTHYILGSALGPHPFPEIVRDFQSVIGREAKQ
                     QYRDMTGQDLPDALVACVGGGSNAIGLFHPFVEDESVAMYGTEAAGLGVDTEHHAATL
                     TKGRPGVLHGSLMDVLQDAHGQILEAFSISAGLDYPGIGPEHSHYHDIKRASYVPVTD
                     EEALEGFQLLSRVEGIIPALESSHAIAFAVKLAKELGPEKSMIVCLSGRGDKDVVQVK
                     DRLEADAAKKGEAHA"
     gene            14129..14905
                     /locus_tag="VQ862_001503"
     CDS             14129..14905
                     /locus_tag="VQ862_001503"
                     /EC_number="4.2.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan synthase subunit alpha"
                     /protein_id="HET3115828.1"
                     /translation="MPKTLTEKLNAIKAAGKGIFVPYIMAGDHEKGLDGLAETIHFLE
                     DLGVSAIEVGIPFSDPVADGPVIEEAGLRSLAHGTSTQALVETLKTIETEIPLVIMTY
                     FNPLFQYGVENFVKDLADTAVKGLIIPDLPHEHANFVEPFLADTDIALIPLVSLTTGI
                     ERQKELIEGAEGFVYAVAINGVTGKSGNYRADLDKHLAQLHQVADIPVLTGFGVSSQA
                     DLERFNAVSDGVIVGSKIVKALHQGEPIQDFIRQAVAYQK"
     gene            complement(14877..14978)
                     /locus_tag="VQ862_001504"
                     /pseudo
     CDS             complement(14877..14978)
                     /locus_tag="VQ862_001504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000234126.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase"
     gene            15207..15347
                     /locus_tag="VQ862_001505"
     CDS             15207..15347
                     /locus_tag="VQ862_001505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000934013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3115829.1"
                     /translation="MLNQDLFDSLEAQKIVDTLMKGQKDYVDERLEKRETMIVSNGYA
                     WT"
     gene            15384..15938
                     /locus_tag="VQ862_001506"
     CDS             15384..15938
                     /locus_tag="VQ862_001506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000464460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3115830.1"
                     /translation="MFEYKLQLAGQTWGYLEFETNTEKYGKVLLIIKGKKRLTNQFPL
                     VQKNKSGYLFEYAQMNTLYLNQHSSYKNDEDSHSFPIQMELVSDEMIQEIEQATKNSN
                     IEKFMILTYEADSENNIISVDVVMPDARTGQLHLIQDLSEYIQSSSYHFEEAKYQDIP
                     NFSELSETEDFEIIPRIEKQEGQK"
     gene            15953..17104
                     /locus_tag="VQ862_001507"
     CDS             15953..17104
                     /locus_tag="VQ862_001507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000481741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HET3115831.1"
                     /translation="MFNGRVLKELRLLNGLSRAELAQRINLTEQAIWQFESNETKPKL
                     STKMHLANQFHVDLTYFEQEEESIRFDSSVIAFRNADLATRKTIDIQTMYLHKVDSLI
                     DYFESFVIIPNIIIHDLSNVVSESYHKGESIEELALYAREKLGISKDNHDLLYKLERS
                     GIYIVERLINGQADAYSAWSKLGRPYIVLGTNKSSVRRNFDLAHELGHILLHKYKDMN
                     EDGDRLEQEANYFASCFLLPKEEFLVKFEERVGKRVSNPDSYILLKSDLNVSIQALEY
                     RAFKLGLLTPKQHSYFYRQIAQKGYKMIEPLDDQIFVKKPSKVKSILDVVLSNHLVSL
                     ATIMSKQSIRLQFISEIFSVEMKFFDQYQEDRRTDRFDNIIPLYKRNNL"
     gene            complement(17156..17815)
                     /locus_tag="VQ862_001508"
     CDS             complement(17156..17815)
                     /locus_tag="VQ862_001508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000564993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase"
                     /protein_id="HET3115832.1"
                     /translation="MIDFYFFLVGSILASFLGLVIDRFPEQSIISSASHCDSCQTPLR
                     PLDLIPILSQVFNRFRCRYCKVRYPVWYALFELGLGLLFLLYSWELLSLGQVVLITAG
                     LTLSIYDFRHQEYPLLVWMTFHLILIASSGWNLVMVSFLALGILAHFIDIRMGAGDFL
                     FLASCALVFSITELLILIQFASATGILAFLLQKKKERLPFVPFLLLATCLIIFGKLLL
                     V"
     gene            17885..>18303
                     /locus_tag="VQ862_001509"
     CDS             17885..>18303
                     /locus_tag="VQ862_001509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000155432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET3115833.1"
                     /translation="MTIRFEEKVSIENAQFVCQWSNSLGKSFQEQWMGSRIPFLLTLQ
                     ALEEVFSIFDEQEFVGLIQKIRLEDSNLHIGRFFINPQKQGQGLGSQALRKFVSLAFE
                     NEDIDSISLNVFEANQRAQNLYQKEGFEIVQMVEAPVR"
BASE COUNT         5901 a         2958 c         3937 g         5507 t
ORIGIN      
        1 tattatcgct taccaatatt tgcttttata tttgctaaac tttcagaaaa aaagttggag
       61 tatatgatgc taggtgactg cgtcatgtta ataaacgaaa tggaaataac tgatcataga
      121 gtagataact tatttgaaaa agggaaaaat gagataaaag atccatgtag tagatttagc
      181 aataggacat ataaaagctt tagaaaaagt atctgaaaaa acagatgttt atatctataa
      241 cctaggctcg ggagaaggca ctagtgtatt acaacttgta aatacatttg aaagtgttaa
      301 taagatccct attccttata aaatagttcc aagacgttca ggagacgttg caatttgtta
      361 tgcaaatgca gacaaagcat ataaggaatt aaattggagg acaacaaaat cgattgaaga
      421 catgtgtaga gatacatgga attggcaatc aaaaaatccc aatgactata attgatgata
      481 ctgtctatat gagtgctgta ttttggaaaa attacttaac cttttaatga aatgcatatt
      541 taatgaaaga taaataaaaa aagtttgaca gcgcttgaca aaggaaacgg tttcattgta
      601 taatgtaaac atggtgacac cgatgtcaaa tataaaaaag aaggtcttta tatgaaaaac
      661 ttaacaaaaa ttaagttcaa agagaatggg gaatttaatc atttctctgg gaatacagtt
      721 gtagcaaatc tttatactaa acaagatttg atggaagttg ttgatattat tcaatcacgt
      781 tatagagaat taccatttat cgataagttt actttaactc caaggaattc tattcacatg
      841 actgtaattg aattgttgtg ccatgaaaat cgtgaaacgg agttttggag cagtaatctt
      901 cctctagata cacctttaca ggaaatacat gattactttg ctaaacaact tgaaattttt
      961 ccattgttgg atgaagaaat tcatatgcgt ataactgaaa tgggaaaaca aaacatacta
     1021 gttgaacctg cagatgaagc ttctgcaaag agattagaag aaattcgtac ttatgtctca
     1081 gaaaaagcag gtgtttgttt ccctaatcat gatagatatc aattccatat ttcaattggg
     1141 tatcttcgga ttcctctaac cgaagaggag gaagaagagt ttactaaagt cagagcagaa
     1201 ttaactgaaa ttttattaga gaagattcca actattactg taaaccgtat tgactatact
     1261 gtatttgaag atatgagaca atttgttcca tatcacgaaa aatttaaata aaataataaa
     1321 aaaggagaac ttatcatgaa aaaaatgaaa gtttggtcta ctgtacttgc aacgggagtt
     1381 gctcttacta cacttgctgc ttgctctgga ggttcaaatt ctacgactgc ttcttcatct
     1441 gaagaaaaag ctgataaaag tcaagaatta gtaatctatt cgaactcagt ctcaaatggt
     1501 cgtggtgatt ggttaactgc taaagcaaaa gaagctggtt ttaatataaa aatggttgat
     1561 atcgctggcg ctcaattagc agaccgtgtt attgctgaga agaataatgc agttgcagat
     1621 atggtatttg gaattggtgc tgttgactca aataaaatta gagatcaaaa attactagta
     1681 cagtacaagc ctaaatggtt agataaaatt gatcaatctt tatcagataa agataattat
     1741 tataatcctg tgattgttca accattagtt ttaattgggg cgcctgatgt aaaagaaatg
     1801 cctaaagatt ggactgaatt aggtagtaag tataaaggta aatattcaat ttatggtctt
     1861 caaggtggta caggacgggc aattctagca agtatcttag ttcgttacct tgatgaaaaa
     1921 ggagatttag gcgtatcaga aaaaggatgg gaagttgcaa aagaatactt tgcaaatgcc
     1981 tatactcttc aaaaaggtga aagctcagtt gttaaagcgt tagataaaga aagcccaatt
     2041 caatacggta tgatctgggg ttctggagcg ttaatcggac aaaaagaaca aaatgttgaa
     2101 ttcaaagtta tgactcctga gattggtgta ccatttgtaa ctgaacaaac tatggtttta
     2161 agcactagta aaaaacaagc gttagctaaa gaatttattg attggtttgg tcaatcagaa
     2221 attcaagtag aatatagtaa aaaatttggc tctatccctg ccaataaaga tgccctaaaa
     2281 gagttacctg aagatacgaa aaaatttgtt gatcaagtga aaccacaaaa tattgactgg
     2341 gaagctgttg gaaagcattt ggatgaatgg gtagaaaaag ctgaattaga atacgtacaa
     2401 taagaaataa gagttatttt ttatgtccaa gtctctctat tatttctaaa tttatggaag
     2461 aaataaagag aggcttttgg tttagtaata gagggagtta gtgagatgat taaatttgat
     2521 aatattcaaa ttaaatatgg tgattttgtt gcaattgata atctgaattt agatatacat
     2581 gaaggggaat tctttacatt tcttgggcct tcaggatgtg gtaaatcaac tactttgaga
     2641 gcattggtag gttttttaga tccatcatca ggaagtattg aagttaatgg aacagatgtc
     2701 actcatttgg aacctgaaaa gcgtggaatt ggtattgtat ttcaatctta tgcgctattt
     2761 ccaactatga ctgtttttga taatattgca tttggtttaa aagttaagaa ggtagctcca
     2821 gatgttatta aagctaaagt atcagcagtg gcagcaaaaa ttaagatctc tgatcaacag
     2881 ttacagcgta atgtatcaga attatctggg ggtcaacaac aaagggtagc attggctcgt
     2941 gctctggttc ttgaacctaa aattctttgt ctagatgaac cattgtcaaa ccttgacgca
     3001 aaattacgtg tagatttgag aaaagagttg aaaagacttc aaaaagagtt aggtattact
     3061 actttatatg ttactcatga tcaagaggaa gccttgactt tatctgatag aattgcagtc
     3121 tttaacaatg gatacatcga acaggtcggt acaccagtag agatttatca taattctcaa
     3181 actgaatttg tatgtgattt tattggagat attaatgttt tgaccgatga aacagtccac
     3241 gaagtattac tgaaaaatac aagcgttttc ttagaagata aaaaaggata cattcgatta
     3301 gagaaagttc gattcaatcg tgaaactgaa caagatttca ttctaaaagg gacaattatt
     3361 gatgttgagt tttctggagt tacaattcac tatacaataa aagtttctga aagtcagatt
     3421 cttaatgtaa caagtattga tagtcaggct gctattagat ctgtcggaga aagtgtggaa
     3481 ttatttatca caccatcaga cgttctgcaa ttttaaggag gtgcagtatg cgtcataaat
     3541 taaatttaaa agattggctt attcgtttag ggttaatctg gttcttagta acatttatta
     3601 tttatccaaa ctttgatcta gtagtgaatg tatttgtaaa aggaggagaa ttttcccttg
     3661 atgctgtaca tcgtgttcta aaatctcaga gggcacttca gagtattatg aacagtttta
     3721 agttagcatt ttcactcatt attacagtta atgtcgtagg tattctttgt gttctattta
     3781 cagagtactt tgatattaaa ggtgctaaaa ttttaaaatt aggttatatg acctctttaa
     3841 tttatggagg agtggtttta gcgactggat ataaatttgt ctatggtcct tatggattga
     3901 ttacaaaatt tttacaaaat gttatccctt ctttagactc taactggttt attgggtatg
     3961 gtgcagtctt attcattatg acattttcag gaactgctaa tcatacattg tttttaacaa
     4021 atacaattcg aagcgttgac tatcacacta ttgaggctgc tcgaaatatg ggagcaaaac
     4081 catttactgt tttccgaaaa gtagtgttac caaccttaat tccaactcta tttgcactta
     4141 ctattatggt ttttcttagt ggtttatctg cagtagcagc acccatgatt gttggtggta
     4201 aagaatttca aactataaat ccaatgatta ttacatttgc agggatgggg aattctcgtg
     4261 atttagctgc cttacttgca attattttag gtattgcaac tacaattttg cttactatca
     4321 tgaataagat agaaaaaggt ggaaattata tttctatctc taagactaaa gcgcctctta
     4381 aaaaacaaaa aattgcgtct aagccttgga atatcattgc tcacattgta gcatatggat
     4441 tgttcacagt tttcatgctt ccactaattt ttatagtatt atactcattt acagatccag
     4501 ttgcaattca aacaggtaac ttaacattat caaactttac tttagaaaat tatcgcttat
     4561 tctttagtaa tagtgcggca ttctctccat tcttggtcag ctttatttat tctattattg
     4621 ctgcgacaac agcaacaatt ctcgcagttg tatttgctcg tgttgtcaga aaacataaat
     4681 ctcgttttga tttcttattt gaatatggtg ctctacttcc ttggttacta ccaagtacac
     4741 ttttagcagt aagtttatta tttactttta atcagccaca atttcttgtc ttgaatcaga
     4801 ttttggtagg tagtttggta attctactta ttgcatatat agttgtaaaa atcccatttt
     4861 cttatagaat ggtacgtgct attttattta gtgttgatga tgagatggaa gatgcagcaa
     4921 gaagtatggg tgcttcacct ttttatacta tgatgaaggt tatcattcca tttattttac
     4981 cggttgttct ctctgttatt gctttaaact ttaactcttt attaactgac ttcgacttat
     5041 ctgtattcct ttaccatccc ctagctcaac cattaggtat tacgattcga tctgcaggtg
     5101 atgaaacagc aacatctaat gcacaagctc tggtatttgt ttatacaatt gttctgatga
     5161 ttatttctgg aacggtatta tacttcacac aaagaccggg gcgtaaagta aggaaataat
     5221 catgacagcc actagtcttg ggttatcaaa tattgaaata gttgtcagga ttgttttatc
     5281 agtagtcatt ggtagtataa ttggtttaga gagagggagc aaatcccagc ctgcaggcat
     5341 ccgaacttat agtattgttt gtctagctgc atgtttgatt atgatgacga atgaatacgt
     5401 atcttataaa tttgggacag gagatcctac acgattagga gctcaagtta tatcaggtgt
     5461 gggttttcta ggcgctggaa cgattcttat tacagataaa aagaaaatta caggtctgac
     5521 aactgcagca ggcatttggg cttcggcagg aattggatta gctattggag taggttttta
     5581 tgagggagct cttttagtag ctatttctgt ttggggtgtg atatccatgt tccaaccact
     5641 aaaaaaatat ctgcaaaatc gttctaaaat gattgaattg tatatagtgg ttaaatctac
     5701 agaagcctat aatcgtgtat tggtttattg tgcagaaaat ggtatcagaa tgaccgattc
     5761 aagaacagcg tttggagatg ttaattctga cagaattgaa tactttgatg ttccagataa
     5821 aaaaatagcg tcatttatta ctctggaatt atcaggtaga tttgaacatc ttcgactgat
     5881 ggaagaaatt gctaatattg taggtgttat ttatgtcgaa gaaattagct gaaatttagt
     5941 aaacaaaggg acagatgttt ttgtcctttt gttttttaga tgttttaatc atctaatttt
     6001 tgagtagatt tttgctcaga ggtttttatg aaagattata aaatcaattt tgatttaggt
     6061 aaaatagaat attttgataa taattgtttg atacaagtat acaaatttat ttctttttat
     6121 gatatttgtg aaatggtgtt tgcctttcat ttacctcctg atgagttgat aacaaatgtt
     6181 atctttaaag aaaaaattaa ctctatgtta aaatgttaaa ttgacaggct attatatgtt
     6241 tttataaatc ctacacattt tactgaaaaa gttaatctac aattttatgg tagttttttc
     6301 tcatatgaat ttatttgtcg tgaagttgga aacattctta aaaataaagg tgtgaaatgc
     6361 aatttaaact tttttgaagg gaaagaatat ttgtaaaatt aattttgtga atttgtggat
     6421 cttaaataat ttactaaatt ctcttgttaa aaaaaattaa atattgtata gtaatattag
     6481 aatgttcgta atggaggact gaaatgaaaa atataaatgg gaaaaaggta actatttatg
     6541 atattgcacg tttatcaggt ttttctccaa aaacagtttc acgagttatt aatggtggag
     6601 taaatgttaa agaagaaact tatcaagcga ttcaaaaagt tatagaggaa ttgtcgtata
     6661 ttccaaatgc gtatgcaaaa aatttaacta aaaaagaagc tataaatata ttgatttctg
     6721 taaaaaaaat cgactctttt cctttaattt ggtttcatac gctgttagat aaagtgttac
     6781 ggacgtgtaa agaatttggt gttaatgcta tagttgagta ctttggagag gaggatacaa
     6841 ttagtaattc aattatatca agcacaggta gcctagtaga tggtgttatt gttttttatg
     6901 aaagtgtaga tgatatcaga attcagtatt taaagaagaa ccatatgcct tttcttgttt
     6961 tcggtgaatc tcaaacgtct ggagtagtct atgtatctaa taataatttt caagctactt
     7021 atgatatgat gaaagctgta actgaagaaa aatttaaaaa tatgtggttg cttatgggag
     7081 gagaatccca tgttaataag gatcgtgaaa gaggtgtgcg ttcttttctg aatgataaaa
     7141 attactttat ggatttaaaa gtcatttatg gcttatctac aattgattca gtttattctt
     7201 atgcaatgca gcacttgact acccaaaatt atccggacat tatttttgtt tcaggagatg
     7261 aaaaggttca aggcttgatt cgtgcgtgct atgagaaagg aattcttatt ccagatgata
     7321 tttctatcat tggatttgat aatattccta tttctcagta ttatactcca gctttgtcta
     7381 caattgctcc caattatgtt aaattggcta aagaaatgat agaaggtgtt ttagcaatta
     7441 ttaaagggga aagtgtcaca tctgttgaag tttctcctaa atttgttagg agacagagtt
     7501 tctagtattg tttaattctt gaaaatccta gtggaaaaga tggagtgttc taaaataagt
     7561 tctgtttagc ctccattcag tttctattga gttggatcca atttctaacg agtgggacat
     7621 gttcatgttc gatctaagga agacatggtc acattcgaat gatattttca aaaaaatcgt
     7681 aaaaaagtct tgacaaagaa aaaacaaagt attaaaataa gttcaacaaa tcagaaaagt
     7741 aactattttt gatcttcagg gagcctgtgg tgattgtgaa taggtggttg gaagtagtga
     7801 aagtgggctg attttgaaaa tgaatttgaa acaatgaaaa ttcggtgcgc acaccttaca
     7861 gtgcagcttg ttgttaaaca aggcagagat gtaaagggat agtcccttta taattgaggt
     7921 ggcaccgcgt taccaacgcc ctcacacgga agtatattct gtgtgtgggc ttttttctat
     7981 ccgtcgtttg ctttatcttt tattagggcc ttaactcgct ttgatgaact tgagttctat
     8041 ctacagctcc ttgcctccta ctaaaagtaa acaaaaaggc tggactaata cgaaaaaagc
     8101 tagtaatact caatgaaaat caaagagcaa actaggaaac tagccgcagg ttgctcaaaa
     8161 cactgttttg aggttgcaga tagaactgac gaagtcagta accataccta cgataaggcg
     8221 acgttgacgc ggtttgaaga gattttcgaa gagtataaag gtgtaccgag atgaacatct
     8281 cttcatcaat gtctctggtc gtggaggcaa ggacctagct gcgattgcag attactagaa
     8341 gctaaaaaat aatagatgga aaaattacag tcttttctct cacagagagc ttgtggttgc
     8401 tgaaaacaag cagagaaagc tgtaaagttg ggttcatctg aaacgagaga agaaaacatc
     8461 attctcaagg gagtgccctt tatcgcacag cctgttacag gaggtatctg agacaggaat
     8521 gagagatagg agaaatccta taattgaggt ggcaccgcga atttcgtcct cacgcaagtt
     8581 attttgcgtg gggatttttc atacagtcgc cacgaactag aattagaact gaaagggaaa
     8641 ttacaatgga acgaatcatt catggagatg tcttatcacc aatcttggct tatatgcgct
     8701 taaaggggca acataaggtt attttagaga gtattccgag agacaaggaa acggctcgtt
     8761 tttctatcct agcctataat ccagtttttg agattaagtt tgaaaatgga gttctctatc
     8821 aaaatggtca agtgattgat cgggatccct tggatttcct ttatgaagtg attcataaga
     8881 gtcagcacca ttcagagctc ccttttggtg gtggagccat tggttttgtg ggttacgata
     8941 tgatttcgct ttatgaagaa attggtcaaa tccctgagga tacaattggg acgccagaca
     9001 tgcatttctt tgtctatgag agctatatgg tctttgacca caagaaggag aagatacatg
     9061 tcatagagga tgcactttat agtgagcgca gtcaagaggc cttggaaaaa tccttgaacc
     9121 aagtgcttga ggaattacgc attcctgctc caaatgaatt tgaagacttg gatttatcac
     9181 cacttgactt caaaccgcat atcgctccac ataagtttga gggaatggta gaaacagctc
     9241 gtgacttgat tcgtaacggt gatatgttcc aatgcgtact cagccagcgc ttctcagcag
     9301 aggttactgg aaatccattt gacttctaca gaaatctccg cgtgactaat ccttctaatt
     9361 acctttattt ctatgatttt ggggattatc aaatcatcgg agccagtcca gaaagtttgg
     9421 tttctgtcaa aaatggcatc gtgacaacca atccgattgc agggacgcga ccaagagggg
     9481 ctacggatga agaagacaag gccttggcga ctgacctcct ctctgatgag aaggaaacag
     9541 cagagcatcg aatgttagta gacctgggtc gtaatgatat tggtcgcatc tctgaaacga
     9601 ccagtgtcca agtcactaag tatatggaag tggagctctt ccgttatgtt atgcatctga
     9661 ccagcgtggt caaggggcgt ttgcttccag aactcactgc catggatgcc ttgaaagcta
     9721 cacttcctgc tggaaccgtt tctggagcac caaagattcg tgctatgaga cgtatctatg
     9781 aactggaaac agaaaaacgg ggcgtatacg caggagcaat cggctacttg tctgcgacgg
     9841 gtgatatgga tttggccatt gccatccgaa ccatgattct caaaaatcaa agagcctatg
     9901 tgcaggctgg ggcagggatt gtctacgact ctatcgccca aaacgaatac caagaaacca
     9961 ttaacaaagc aaaatctatg actagaattg gagaactaag accatgattt tattgattga
    10021 caactatgat tcttttacct ataacttggc ccaatacatt gggaattttg cagaagttca
    10081 ggttctgaga aatgatgatt ccaagctgta tgaagaagct gaaaaagcag atggtctggt
    10141 cttttctcct ggtcctggtt ggccagttga tgctggaaag atggaagaca tgattcgtga
    10201 ctttgcaggc aagaagccga ttctagggat ttgtttaggc caccaagcca ttgcagaagt
    10261 ctttggtggt aagctaggtt tggctccaaa agtcatgcat gggaaacaga gcaatatcaa
    10321 ctttgaagcg ccatctgttt tgtatcaagg tattgaggat gaccgtgcgg tcatgcgtta
    10381 tcacagtatt ttgattgagg aaatgccaga agactttgaa gtgacagctc gttcgactga
    10441 tgaccaagcc atcatgggga ttcaacataa aaacctaccg atttatggct tccagtacca
    10501 tccagagagc attggaacgc cagacggctt gtcttctatt cggaatttta tcgagaaggt
    10561 tgtaaagtga ggaaactagg atgaaagaga ttattgaaaa actagcaaaa tttgaaaatt
    10621 tatcaggtgt ggaaatgacg gatgtcattg agcgtatcgt aactgggcgt gtaactgaag
    10681 cgcagattgc ttctctcctc ttagctctta agatgaaggg ggaaacacct gaagaacgca
    10741 cagccattgc ccgagtcatg agaggacatg cccagcatat tccaactgag attcatgatg
    10801 ctatggacaa ctgtggtaca ggtggggaca agtctttcag ttttaatatt tccacaactg
    10861 cagcctttgt cttggctggt ggcggtattc acatggccaa gcatggtaac cgctcgattt
    10921 cttctaaatc tggttccgca gatgtcctcg aagccttggg aatcaatctt gacctcaaac
    10981 cagctgaact aggtaaggtc tttgataaaa ctggcatcgt ctttctcttc gctaaaaata
    11041 tgcacccagc tatgaaatac atcatgccag ctcgtttgga attgggaatt ccaacgatta
    11101 tgaacttgac tggtccactg attcatccaa tggctttaga aacacagctt cttggaatta
    11161 gtcgtccaga actcctagaa agtacagctc aggttttgaa aaatatgggt cgcaaacgtg
    11221 ccatcgtggt tgctggacca gaagggttgg atgaagctgg cttgaacgga acaaccaaga
    11281 ttgcacttct tgaaaatggc gaaatcagct tgtcaagctt tactccagag gatttgggaa
    11341 tggaaggcta tgctatggaa gatattcgtg gtgggaatgc tcaggaaaat gcagaaattt
    11401 tgcttagcgt tctgaaaaac gaagcaagtc cattcttgga aacgacagtc ttgaatgctg
    11461 gtcttggttt ctatgctaat ggtaagattg atagcatcaa ggaaggagtt gccttggccc
    11521 gtcaagtgat tgctagaggc aaggcccttg aaaaactcag actgttacag gagtaccaaa
    11581 aatgagtcag gaatttttag cacgaatctt ggagcagaag gcgcgtgagg tggagcagat
    11641 gaagctggag caaatccagc ctctgcgcca gacctatcgc ttggcagaat ttttgaagaa
    11701 tcatcaggac cgcttgcagg taatcgctga ggtcaagaaa gctagcccta gtttgggaga
    11761 tatcaatctc gatgtggata ttgtgcaaca ggcccagact tatgaagaaa acggagcagt
    11821 gatgatttcg gtgttgacag atgaggtttt ctttaaaggg catttggatt atctacggga
    11881 aatttccagt caggtagaga ttccgacgct caacaaagac tttatcatag atgaaaagca
    11941 aatcatccgc gctcgcaatg caggtgcgac agttatcttg cttattgtgg cagccttgtc
    12001 cgaagaacgc ctcaaggaac tgtatgacta cgcgacagag cttggtctgg aagtcttagt
    12061 ggagactcac aatctagctg aactagaggt agcccacaga cttggtgctg agattatcgg
    12121 ggtcaacaac cgcaacttga ctacctttga ggtcgacttg cagaccagtg tagatttagc
    12181 cccttacttt gaggaaggtc gctattacat ttctgaatct gccattttca cagggcagga
    12241 tgcggaacga ctagccccat actttaacgg aattttggta gggacagctc ttatgcaggc
    12301 agaaaatgtg gcccagagaa tcaaggagtt gcagattgac aaaggttaaa atttgtggac
    12361 tatcgaccaa agaagcggtg gaaacagccg tttcagcagg agccgactat atcggttttg
    12421 tctttgcacc tagtaaaaga caggtgactt tagaagaggc agctgtgttg gcaaagctta
    12481 ttcctgcaga tgtgaaaaag gttggagtat ttgtttcacc aagtcgggta gaactgctgg
    12541 aagcgattga caaagttggc ttggacttgg ttcaagttca cggtcaggtg gcagatgatt
    12601 tatttgagaa tttgccttgt gccagtattc aggctgtgca ggtagatgga aatgggcatg
    12661 tccccaattc tcaggcagat tatctactct ttgatgcccc tgtggcagga agtggccagc
    12721 cctttgattg gggtcaactg gatacgactg gactagcaca gcccttcttt atcgcaggtg
    12781 gccttaatga agataatgta gtaaaagcaa ttcaacattt tactccctat gcagtagatg
    12841 tatcgagcgg agtggagaca gatggacaaa aagatcatga aaagattaga agatttatag
    12901 agagggtaaa gcatggcata tcaggaacca aataaagatg gattttacgg aaaattcggc
    12961 ggacgttttg tcccagaaac attgatgaca gcagttttgg agttggagaa ggcctaccgt
    13021 gaaagtcagg cagacccaag tttccaagag gaattaaacc agcttttgcg ccagtacgta
    13081 ggacgtgaaa ctcctcttta ttacgcaaaa aacttgaccc agcatatcgg cggagccaag
    13141 atttatctca aacgggaaga ccttaaccat acaggagccc acaagattaa caatgcctta
    13201 ggacaagttt ggcttgccaa acgcatgggt aaaaagaaaa ttatcgcaga aacgggtgct
    13261 ggtcagcacg gtgtggcaac tgcaactgct gcggccctct ttaacatgga atgtaccatc
    13321 tacatgggtg aggaagatgt caaacgccaa gccctcaatg tcttccgtat ggagcttttg
    13381 ggagctaagg tcgaggccgt gacagatggt tcgcgcgtgc tcaaggatgc ggtcaatgca
    13441 gcccttcgtt catgggtagc taatatcgat gatacccact atatccttgg ttctgccttg
    13501 gggcctcatc catttccaga aatcgttcgt gacttccaaa gtgtcatcgg tcgagaggct
    13561 aaacaacagt accgcgatat gacaggtcaa gatctgccag atgccctagt agcctgtgtt
    13621 ggtggtgggt cgaatgctat cgggctcttc catccctttg tagaagatga gtcagtagct
    13681 atgtatggaa ctgaagcagc agggcttggt gtggatacag agcaccacgc tgctaccttg
    13741 accaagggtc gtccgggtgt tcttcacggt tctctcatgg atgtgctcca agatgcccat
    13801 ggtcaaattc ttgaagcctt ctctatctca gcaggtttgg actatcctgg tattggtcca
    13861 gaacattctc actaccacga tatcaaacgt gccagctatg tccctgtgac agatgaagaa
    13921 gccttggaag gattccaact cttgtctcgt gtggaaggga ttatcccagc cttggaatct
    13981 agccatgcta tcgcttttgc ggtgaaattg gccaaagaac ttggaccaga aaagtctatg
    14041 attgtctgcc tatcaggtcg tggggacaag gatgtggttc aagtcaaaga ccgcttggaa
    14101 gcagatgcag caaagaaggg agaagctcat gcctaagaca ctaacagaaa aattgaatgc
    14161 tattaaagca gctggaaaag gaatttttgt tccctatatc atggctggtg accacgagaa
    14221 aggtttggac ggtcttgctg aaacaattca ctttttagaa gatttgggtg tctctgcaat
    14281 tgaagtgggt attccctttt cagaccctgt tgcagatgga cctgttatcg aagaagctgg
    14341 cttgcgcagt ttagcccacg ggacctctac ccaggcttta gttgaaacct tgaaaaccat
    14401 tgaaacagag attccactgg tcatcatgac ctacttcaac cccctctttc agtacggtgt
    14461 ggagaacttt gtcaaagatc tggctgatac agctgtgaag ggcttgatta tcccagactt
    14521 gcctcatgaa catgccaact ttgtagaacc atttttggca gatacagata tcgccttgat
    14581 tcctttagta agcttgacca caggaattga gcgccagaaa gagttgattg aaggcgcgga
    14641 gggattcgtc tatgccgttg ccatcaatgg ggtgacaggg aaatcaggca attaccgtgc
    14701 agatttggac aagcacttgg cgcaacttca tcaagtggcc gacatcccag tcttgacagg
    14761 ttttggtgta tctagtcaag ccgatctgga acgcttcaat gcggtgtcag atggtgttat
    14821 cgtcggttcg aaaatagtaa aagctctcca ccaaggagag ccgattcagg attttatcag
    14881 acaagcagta gcttaccaaa aataatcaaa caagtagcaa gtaagaggaa aggcacgaaa
    14941 ggaagtcttt cctttttctt ttgcaggcga aaggctagtt ttatagtgaa ttgaatctgg
    15001 aatattacac tacggttcct aaaatatttt aagaaagtga tttgaatttc ccaataaatt
    15061 tgttcagttt ttaattgatt ttactataga agatataatt ttctaaatta ctctgacaca
    15121 gaactttaag aaaaagctaa ttattgtagt aatttcttta agaaaatgat ataattcatt
    15181 aaaaagtatt tggaggagga agaattatgt tgaatcagga tctctttgat tcgcttgagg
    15241 cacaaaaaat tgtagatact ttgatgaaag ggcaaaaaga ttatgtagat gaacgtctag
    15301 aaaaaagaga gacaatgata gtgtcgaatg gttatgcatg gacgtgacct aatcatattg
    15361 atactgcatt tgcatcagca gatttgtttg agtataaatt acaattagca ggacagactt
    15421 ggggatattt agaatttgaa acaaatacag aaaaatatgg gaaagtattg ttaattataa
    15481 agggtaagaa gcgacttacg aaccaatttc ctttggtaca aaaaaataag agtggctact
    15541 tatttgaata tgctcagatg aatacacttt atcttaatca acattcttcc tacaaaaatg
    15601 atgaagatag tcattccttt ccaattcaga tggagttagt ttctgatgaa atgattcaag
    15661 aaattgaaca agctactaaa aattcgaata tcgaaaaatt tatgatttta acttatgagg
    15721 cggactcaga aaacaatatt atatctgtag atgttgttat gcctgatgca cgaactggtc
    15781 agttacactt gattcaagat ttgtctgagt atattcaatc aagttcgtac catttcgaag
    15841 aagctaaata tcaagatatt cctaattttt cagaattatc ggaaacagaa gattttgaaa
    15901 ttattccaag aatagaaaaa caagaaggtc aaaagtagta aggagtatgt aaatgtttaa
    15961 tggtcgggta ttgaaagaat tacggctgtt aaatggttta agtagagcag aattagctca
    16021 gagaattaat ttaacggaac aagccatttg gcagtttgag tccaacgaaa cgaaacctaa
    16081 attatcaacc aaaatgcatt tggccaacca atttcatgtt gatttaactt attttgaaca
    16141 ggaagaagag agcattcgat ttgattcttc tgtaattgcc tttagaaatg cagacctagc
    16201 aacacggaaa acaatagata ttcaaactat gtatttacat aaggtagata gtttgattga
    16261 ttattttgaa agttttgtaa ttatacctaa tattataatt catgacctaa gtaatgtagt
    16321 gagtgaatct tatcataagg gagaatccat tgaggaattg gctctttatg ccagggaaaa
    16381 attaggtatt tcaaaagata atcatgattt gctttataaa ttagaacgtt caggcatcta
    16441 tatcgtggaa cgattaatta atggccaagc tgatgcttat agcgcatggt caaaattggg
    16501 aagaccttat attgtgttgg gaacgaataa atcatctgta cgtcgaaatt ttgacttagc
    16561 tcatgagcta ggacatattc ttttacataa atataaagat atgaatgaag atggcgatcg
    16621 tttggagcaa gaagcaaatt attttgcatc atgtttttta ttgccaaaag aagagttttt
    16681 agtcaaattt gaagagaggg ttggcaagcg tgtcagcaat cctgatagtt atattttatt
    16741 gaagtcggat ttgaatgttt cgatacaggc tttagagtat cgagctttta agttaggatt
    16801 attgactcca aagcaacatt cttactttta tcgtcaaatt gcgcaaaaag gttacaaaat
    16861 gattgaacct ttggatgatc aaatttttgt taaaaaacca agcaaagtaa agagtattct
    16921 ggacgtcgtt ttgagtaatc atctagtcag tctagcgact ataatgtcta aacaaagtat
    16981 tcgtttacag tttataagcg aaatattttc agtcgaaatg aaattttttg atcagtatca
    17041 agaagataga agaacagatc gatttgataa catcatccct ttgtacaaaa gaaataattt
    17101 ataatttaac tgtgaaataa tttcatgaag gacatatggc agaaattgga ctttatcaaa
    17161 caagcagtag cttaccaaaa ataatcaaac aagtagcaag taagaggaaa ggcacgaaag
    17221 gaagtctttc ctttttcttt tgcaggagaa aggctaggat acccgtcgca gaagcaaact
    17281 gaatcaagat cagtaactcc gttatgctaa agacgagagc acaagaagct aaaaagagga
    17341 aatcccctgc gcccatgcgg atatcgataa aatgagccaa aattccaaga gcaaggaagg
    17401 agaccatgac cagattccag ccagaggaag ctattaggat taggtggaaa gtcatccaga
    17461 ccagtaaggg atattcctga tggcgaaagt catagatgct caaggtcaaa ccagcggtga
    17521 ttaggacgac ttgccccaag gaaagcaatt cccaagagta aagcagaaag aggagtccta
    17581 agcctagttc aaagagggca taccagacag gatagcggac cttgcagtag cgacagcgaa
    17641 agcgattgaa gacctgtgag agaatcggaa tcaaatctaa gggacgcaag ggagtctgac
    17701 aggaatcgca gtgactggct gaactgataa tggattgctc tggaaaacgg tcaatgacca
    17761 aaccaagaaa ggaagcgaga atgctcccga cgagaaaaaa ataaaaatca atcatactta
    17821 tctattcgta aaaaatggga gaaatagtat aatggagaaa catagataag atggtgagga
    17881 aaagatgaca attcgttttg aagaaaaggt gagtatagaa aacgctcaat ttgtatgcca
    17941 atggtccaac tccctaggca aatcctttca agaacaatgg atgggatcaa ggattccttt
    18001 tctactgacc cttcaagcct tggaagaagt cttttcaatc tttgatgaac aagagtttgt
    18061 gggacttatc cagaaaatca ggctagaaga cagcaatctt catatcggga gattttttat
    18121 caacccccag aaacaggggc aaggcttagg tagccaggct ttaaggaaat ttgttagttt
    18181 ggcctttgaa aatgaagata tagatagtat ttctctaaat gtcttcgagg caaatcaaag
    18241 agctcagaat ctttaccaaa aagaaggatt tgaaatcgtt caaatggttg aagcacctgt
    18301 acg
//
LOCUS       DAVBOD010000042        18138 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 640-05
            SAMEA1012484-rid20186543.denovo.042, whole genome shotgun sequence.
ACCESSION   DAVBOD010000042 DAVBOD010000000
VERSION     DAVBOD010000042.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012484
            Sequence Read Archive: ERR059358
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 18138)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18138)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979948.1
            Genome Coverage       :: 595x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:03:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,266
            CDSs (total)                      :: 2,219
            Genes (coding)                    :: 2,091
            CDSs (with protein)               :: 2,091
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 71 of 128
            Pseudo Genes (incomplete)         :: 50 of 128
            Pseudo Genes (internal stop)      :: 33 of 128
            Pseudo Genes (multiple problems)  :: 22 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18138
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012484-rid20186543.denovo.042"
                     /strain="NIG 640-05"
                     /db_xref="taxon:1313"
     gene            complement(<1..839)
                     /gene="lytB"
                     /locus_tag="VQ862_001510"
     CDS             complement(<1..839)
                     /gene="lytB"
                     /locus_tag="VQ862_001510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010976495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endo-beta-N-acetylglucosaminidase"
                     /protein_id="HET3115834.1"
                     /translation="MNLGEFWYNKINKNRGRRLMKKVRFIFLALLFFLASPEGAMASD
                     GTWQGKQYLKEDGSQAANEWVFDTHYQSWFYIKADANYTENEWLKQGDDYFYLKSGGY
                     MAKSEWVEDKGAFYYLDQDGKMKRNAWVGTSYVGATGAKVIEDWVYDSQYDAWFYIKA
                     DGQHAEKEWLQIKGKDYYFKSGGYLLTSQWINQAYVNASGAKVQQGWLFDKQYQSWFY
                     IKENGNYADKEWIFENGHYYYLKSGGYMAANEWIWDKESWFYLKFDGKIAEKEWVYDS
                     HSQA"
     gene            complement(881..1867)
                     /locus_tag="VQ862_001511"
     CDS             complement(881..1867)
                     /locus_tag="VQ862_001511"
                     /EC_number="1.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013193458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase"
                     /protein_id="HET3115835.1"
                     /translation="MVLFSAQEQLYYKEKIMTTNRLQVSLPGLDLKNPIIPASGCFGF
                     GQEYAKYYDLNLLGSIMIKATTLEPRFGNPTPRVAETPAGMLNAIGLQNPGLEVVLAE
                     KLPWLEREYPNLPIIANVAGFSKQEYAAVSHGISKATNVKAIELNISCPNVDHCNHGL
                     LIGQDPDLAYDVVKAAVEASEVPVYVKLTPSVTDIVTVAKAAEDAGASGLTMINTLVG
                     MRFDLKTRKPILANGTGGMSGPAVFPVALKLIRQVAQTTDLPIIGMGGVDSAEAALEM
                     YLAGASAIGVGTANFTNPYACPDIIENLPKVMDKYGISSLEELRQEVKESLR"
     gene            complement(1830..2630)
                     /locus_tag="VQ862_001512"
     CDS             complement(1830..2630)
                     /locus_tag="VQ862_001512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase electron transfer
                     subunit"
                     /protein_id="HET3115836.1"
                     /translation="MNPTCKKRLGVIRLETMKVVAQEEIAPAIFELVLEGEMVEAMRA
                     GQFLHLRVPDDAHLLRRPISISSIDKANKQCHLIYRIEGAGTAIFSTLSQGDTLDVMG
                     PQGNGFDLSDLDEQNQVLLVGGGIGVPPLLEVAKELHERGVKVVTVLGFANKDAVILK
                     TELAQYGQVFVTTDDGSYGIKGNVSVVINDLDSQFDAVYSCGAPGMMKYINQTFDDHP
                     RAYLSLESRMACGMGACYACVLKVPESETVSQRVCEDGPVFRTGTVVL"
     gene            complement(2880..3260)
                     /locus_tag="VQ862_001513"
     CDS             complement(2880..3260)
                     /locus_tag="VQ862_001513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HET3115837.1"
                     /translation="MASKMLHTCLRVENLEKSIAFYQDAFGFKELRRRDFPDHAFTIV
                     YLGLEGDDYELELTYNYDHGPYVVGDGFAHIALSTPDLEALHQEHSAKGYEVTEPNGL
                     PGTTPNYYFVKDPDGYKVEVIREK"
     gene            complement(3318..3677)
                     /gene="rplT"
                     /locus_tag="VQ862_001514"
     CDS             complement(3318..3677)
                     /gene="rplT"
                     /locus_tag="VQ862_001514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019786714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L20"
                     /protein_id="HET3115838.1"
                     /translation="MARVKGGVVSRKRRKRILKLAKGYYGAKHILFRTAKEQVMNSYY
                     YAYRDRRQKKRDFRKLWITRINAAARMNGLSYSQLMHGLKLAEIEVNRKMLADLAVND
                     AVAFTALADAAKAKLGK"
     gene            complement(3729..3929)
                     /gene="rpmI"
                     /locus_tag="VQ862_001515"
     CDS             complement(3729..3929)
                     /gene="rpmI"
                     /locus_tag="VQ862_001515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001125942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L35"
                     /protein_id="HET3115839.1"
                     /translation="MPKQKTHRASAKRFKRTGSGGLKRFRAYTSHRFHGKTKKQRRHL
                     RKASMVHSGDYKRIKAMLTRLK"
     gene            complement(3962..4492)
                     /gene="infC"
                     /locus_tag="VQ862_001516"
     CDS             complement(3962..4492)
                     /gene="infC"
                     /locus_tag="VQ862_001516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000848185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-3"
                     /protein_id="HET3115840.1"
                     /translation="MKTIAKQDLFINDEIRVREVRLIGLEGEQLGIKPLSEAQALADN
                     ANVDLVLIQPQAKPPVAKIMDYGKFKFEYQKKQKEQRKKQSVVTVKEVRLSPTIDKGD
                     FDTKLRNARKFLEKGNKVKVSIRFKGRMITHKEIGAKVLAEFAEATQDIAIIEQRAKM
                     DGRQMFMQLAPATDKK"
     misc_feature    complement(4508..4639)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00558"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L20 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00558"
     gene            complement(4805..5989)
                     /locus_tag="VQ862_001517"
     CDS             complement(4805..5989)
                     /locus_tag="VQ862_001517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000655955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3115841.1"
                     /translation="MKDVSLFLLKKVFKSRLNWIILLLFASVLGVTFYLNSQTANSHS
                     LESRLESRIAANERAINENEEKLSQMSDTSSEEYQFAKNNLDVQKNLLTRKTEILTLL
                     KEGRWKEAYYLQWQDEEKNYEFVSNDPTASSGLKMGVDRERKIYQALYPLNIKAHTLE
                     FPTHGIDQIVWILEVIIPSLFVVAIIFMLTQLFAERYQNHLDTAHLYPVSKVTFAISS
                     LGVGVGYVTVLFIGICGFSFLVGSLISGFGQLDYPYPIYSLVNQEVTIGKIQDVLFPG
                     LLLAFLAFIVIVEVVYLIAYFFKQKMPVLFLSLIGIVGLLFGIQTIQPLQRIAHLIPF
                     TYLRSVEILSGRLSKQIDNVDLNWSMGMVLLPCLIILLLVGILFIESWGSSRKKEVFN
                     RS"
     gene            complement(5993..6580)
                     /locus_tag="VQ862_001518"
     CDS             complement(5993..6580)
                     /locus_tag="VQ862_001518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000939891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3115842.1"
                     /translation="MLQLTHVTLKTRQVILQDVDFTFKKGRVYGLLAINGSGKTTLFR
                     AISNLIPISSGNIAAPPSLFYYESIEWLDGNLSGMDYLRLIKNIWKSGLNLRDEIAYW
                     EMSDYISLPIRKYSLGMKQRLVIAMYFLSQAKCWLMDEITNGLDEYYRQKFFDRLAQI
                     DRQEQLVLLSSHYKEELVDVCDRVVTIHQGQIEEV"
     gene            complement(6613..6801)
                     /locus_tag="VQ862_001519"
     CDS             complement(6613..6801)
                     /locus_tag="VQ862_001519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3115843.1"
                     /translation="MTVTKSYKYDWNTVWEYSTNYHDHQYAWIPSWSRYDSYSEYKVG
                     GGWNYGRYEVINYYSGGY"
     gene            complement(6980..9220)
                     /locus_tag="VQ862_001520"
     CDS             complement(6980..9220)
                     /locus_tag="VQ862_001520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA internalization-related competence protein
                     ComEC/Rec2"
                     /protein_id="HET3115844.1"
                     /translation="MLQWIKNFSIPLIYLSFLLLWLYYAIFSVSYFALLGFVFLLVCL
                     FIQFPWKSAGKVLVICGVFGFWFLFQTWQQSQVSQNLVDSVERVRILPDTIKVNGDSL
                     SFRGKSDGRAFQVYYKLQSEEEKEAFQALTDLHEIGLEGKLSEPEGQRNFGGFDYQGY
                     LKTQGIYQTLNIKRIQSFQKVGSWDIGENLSSLRRKAVVWIKMHFPDPMRNYMTGLLL
                     GHLDTDFEEMNELYSSLGIIHLFALSGMQVGFFMDGFKKLLLRLGLTQEKLKWLTYPF
                     SLIYAGLTGFSASVIRSLLQKLLAQHGVKGLDNFALTVLVLFIVMPNFFLTAGGVLSC
                     AYAFILTMTSKEGEGLKAVTSESLVISLGILPILSFYFAEFQPWSILLTFVFSFLFDL
                     VFLPLLSILFVLSFLYPVIQLNFIFEWLEGIIRLVSQVARRPLVFGQPNAWLLILLLI
                     SLALVYDLRKNIKGLTVLSLLITGLFFLTKYPLENEITMLDVGQGESIFLRDVTGKTI
                     LIDVGGKAESYKKIEKWQEKMTTSNAQRTLIPYLKSRGVAKIDQLILTNTDKENVGDL
                     SEVTKAFHVGEILVSKDSLKQKEFVAELQATQTKVRSMTVGENLPIFGSQLEVLSPRK
                     MGDGGHDDTLVLYGKFLDKQFLFTGNLEEKGEKDLLKHYPDLKVNVLKASQQGNKKSS
                     SPAFLEKLKPELTLISVGKSNRMKLPHQETLTRLEGINSKVYRTDQQGAIRFKGVDSW
                     KIESVR"
     gene            complement(9204..9854)
                     /locus_tag="VQ862_001521"
     CDS             complement(9204..9854)
                     /locus_tag="VQ862_001521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000387331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-hairpin-helix domain-containing protein"
                     /protein_id="HET3115845.1"
                     /translation="MEAIIEKIKEYKIIVICTGLGLLVGGFFLLKPAPQTSVKETNLQ
                     AEVAAVSKDSSTGKEVNKEEKEEPVEQDLITVDVKGAVKSPGIYDLPVGSRVNDAVQK
                     AGGLTEQADSKSLNLAQKVSDEALVYVPTKGEEAVSQQTGSGTASSTSKEKKVNLNKA
                     SLEELKQVKGLGGKRAQDIIDHREANGKFKSVDELKKVSGIGAKTIEKLKDYVTVD"
     gene            complement(9922..10491)
                     /locus_tag="VQ862_001522"
     CDS             complement(9922..10491)
                     /locus_tag="VQ862_001522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000443767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET3115846.1"
                     /translation="MESIFVKFAQYPSIETERLLLRPVTLDDAEAMFDYASDKGNTRY
                     TFPTNQSLEETKNNIAQFYLANPLGRWGIELKDNGKFIGTIDLHKIDPVLKKAAIGYI
                     INKKYWNQGLTTEANRAVIELAFEKIGMNKLTALHDKANPASGKVMEKSGMRFSHAEP
                     YACMDQHEKGRIVTRVHYVLTKEDYFANK"
     gene            10668..11779
                     /gene="ald"
                     /locus_tag="VQ862_001523"
                     /pseudo
     CDS             10668..11779
                     /gene="ald"
                     /locus_tag="VQ862_001523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004253293.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="alanine dehydrogenase"
     gene            complement(12146..12406)
                     /locus_tag="VQ862_001524"
                     /pseudo
     CDS             complement(12146..12406)
                     /locus_tag="VQ862_001524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003069408.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TfoX/Sxy family protein"
     gene            complement(12409..12909)
                     /locus_tag="VQ862_001525"
     CDS             complement(12409..12909)
                     /locus_tag="VQ862_001525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000566985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET3115847.1"
                     /translation="MIDQLSKYYSCRILTEKDIPSILSLYESNPLYFQHCPPEPNFAT
                     VKEDMLCLPEGKAKADKFFVGFWNGSDLVAVMDFVYAYPDEETVFIGLFMVDQAYQRK
                     GIGSHIVTEALAYFAKNFRKARLAYVKGNPQSQHFWEKQGFKSIGCEVKQELYTVVIA
                     EQSLED"
     gene            complement(13089..14057)
                     /locus_tag="VQ862_001526"
     CDS             complement(13089..14057)
                     /locus_tag="VQ862_001526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhoH family protein"
                     /protein_id="HET3115848.1"
                     /translation="MKEHSIDIQLSHPDDLFHLFGSNERHLRLMEEELDVVIHARTEI
                     VQVLGEESACEEARQVIQALMALVNRGMTVGTPDVVTAISMVKNDEIDKFVALYEEEI
                     IKDNTGKPIRVKTLGQKLYVDSVKQHDVTFGIGPAGTGKTFLAVTLAVTALKRGQVKR
                     IILTRPAVEAGESLGFLPGDLKEKVDPYLRPVYDALYQILGKDQTTRLMEREIIEIAP
                     LAYMRGRTLDDAFVILDEAQNTTIMQMKMFLTRLGFHSKMIVNGDISQIDLPRNVKSG
                     LIDAQDKLKNIHQIDFVHFSAKDVVRHPVVAQIIRAYEYSTEVAHD"
     gene            complement(14143..14358)
                     /locus_tag="VQ862_001527"
     CDS             complement(14143..14358)
                     /locus_tag="VQ862_001527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YozE family protein"
                     /protein_id="HET3115849.1"
                     /translation="MRKSFYTWLMTERNPKSNNPKAILADLAFEEAAFPKHTDDFDEV
                     SRFLEEHASFSFNLGDFDSIWQEYLEH"
     gene            complement(14367..15221)
                     /gene="cvfB"
                     /locus_tag="VQ862_001528"
     CDS             complement(14367..15221)
                     /gene="cvfB"
                     /locus_tag="VQ862_001528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001095444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding virulence regulatory protein CvfB"
                     /protein_id="HET3115850.1"
                     /translation="MNTNLASFIVGLIIDENDRFYFVQKDGQTYALAKEEGQHTVGDT
                     VKGFAYTDMKQKLRLTSLEVTATQDQFGWGRVTEVRKDLGVFVDTGLPDKEIVVSLDI
                     LPELKELWPKKGDQLYIRLEVDKKDRIWGLLAYQEDFQRLARPAYNNMQNQNWPAIVY
                     RLKLSGTFVYLPENNMLGFIHPSERYAEPRLGQVLDARVIGFREVDRTLNLSLKPRSF
                     EMLENDAQMILTYLESNGGFMTLNDKSSPDDIKATFGISKGQFKKALGGLMKAGKIKQ
                     DQFGTELI"
     gene            complement(15281..15838)
                     /gene="frr"
                     /locus_tag="VQ862_001529"
     CDS             complement(15281..15838)
                     /gene="frr"
                     /locus_tag="VQ862_001529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006148672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome recycling factor"
                     /protein_id="HET3115851.1"
                     /translation="MANAIIEKAKERMTQSHQSLAREFGGIRAGRANASLLDRIHVEY
                     YGVETPLNQIASITIPEARVLLVTPFDKSSLKDIERALNASDLGITPANDGSVIRLVV
                     PALTEETRRDLAKEVKKVGENAKVAVRNIRRDAMDEAKKQEKAKEITEDELKTLEKDI
                     QKVTDDAVKHIDDMTANKEKELLEV"
     gene            complement(15847..16584)
                     /locus_tag="VQ862_001530"
     CDS             complement(15847..16584)
                     /locus_tag="VQ862_001530"
                     /EC_number="2.7.4.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000013002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UMP kinase"
                     /protein_id="HET3115852.1"
                     /translation="MANPKYKRILIKLSGEALAGERGVGIDIQTVQTIAKEIQEVHSL
                     GIEIALVIGGGNLWRGEPAAEAGMDRVQADYTGMLGTVMNALVMADSLQQVGVDTRVQ
                     TAIAMQQVAEPYVRGRALRHLEKGRIVIFGAGIGSPYFSTDTTAALRAAEIEADAILM
                     AKNGVDGVYNADPKKDKTAVKFEELTHRDVINKGLRIMDSTASTLSMDNDIDLVVFNM
                     NQSGNIKRVVFGENIGTTVSNNIEEKE"
     gene            complement(16668..18002)
                     /gene="trmFO"
                     /locus_tag="VQ862_001531"
     CDS             complement(16668..18002)
                     /gene="trmFO"
                     /locus_tag="VQ862_001531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000083696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate--tRNA-(uracil(54)-
                     C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO"
                     /protein_id="HET3115853.1"
                     /translation="MSQSYINVIGAGLAGSEAAYQIAERGIPVKLYEMRGVKSTPQHK
                     TDNFAELVCSNSLRGDALTNAVGLLKEEMRRLGSVILESAEATRVPAGGALAVDRDGF
                     SQMVTEKVVNHPLIEVVRDEITELPTDVITVVATGPLTSDALAEKIHALNNGDGFYFY
                     DAAAPIIDVNTIDMSKVYLKSRYDKGEAAYLNAPMTKQEFMDFHEALVNAEEAPLNSF
                     EKEKYFEGCMPIEVMAKRGIKTMLYGPMKPVGLEYPDDYTGPRDGEFKTPYAVVQLRQ
                     DNAAGSLYNIVGFQTHLKWGEQKRVFQMIPGLENAEFVRYGVMHRNSYMDSPNLLEQT
                     YRSKKQPNLFFAGQMTGVEGYVESAASGLVAGINAARLFKEESEVIFPETTAIGSLAH
                     YITHADSKHFQPMNVNFGIIKELEGERIRDKKARYEKIAERALADLEEFLTV"
BASE COUNT         5186 a         4136 c         3375 g         5441 t
ORIGIN      
        1 gcttgactat gagaatcgta gacccattct ttttcagcta ttttcccatc aaatttgaga
       61 taaaaccaag attccttatc ccaaatccat tcattggctg ccatgtagcc accagatttt
      121 agataataat agtgaccatt ctcgaaaatc cattctttat cagcatagtt tccattttct
      181 tttatgtaaa accaagattg gtattgtttg tcaaaaagcc aaccttgctg tactttggca
      241 ccactagcat tcacataagc ttgattaatc cactgacttg ttagtagata accaccggat
      301 ttgaaataat agtccttccc tttaatttgg agccattctt tctctgcgtg ctgtccatct
      361 gctttgatat aaaaccaagc atcgtattga gaatcataga cccagtcttc tattactttg
      421 gcacctgttg caccaacata ggaagttcct acccaagcat ttcttttcat ctttccatct
      481 tggtcaagat aataaaaggc tcccttgtct tctacccatt ctgatttggc catatagcca
      541 ccagatttga ggtaaaaata gtcgtcacct tgctttagcc attcattttc agtatagtta
      601 gcatctgctt ttatatagaa ccaagattga taatgagtat caaaaaccca ctcattcgct
      661 gcttgactgc catcttcttt cagatactgt tttccttgcc aagtaccatc actagccatt
      721 gcaccctctg gactagctaa gaaaaatagc agagctaaaa aaataaatct tactttcttc
      781 attaaccttc ttcctctgtt cttatttatt ttattgtacc aaaattctcc taaattcata
      841 ttacaaacta ataaaaaatc aagaacagat tgattgcagt ttacctcaga gactctttta
      901 cttcctgacg gagttcttcc agactgctaa taccgtattt atccatgact tttggtaaat
      961 tttcgatgat gtcagggcag gcataaggat tggtaaagtt agctgttcca actccgatag
     1021 cagatgcccc agccagatac atttctaggg cagcttcagc cgaatccact ccccccattc
     1081 caatgatagg caggtctgtt gtttgggcta cttggcggat gagtttgagg gctactggaa
     1141 agactgctgg acctgacatt ccacctgttc cattggccaa gattggtttt ctggttttga
     1201 ggtcaaagcg cattccaacc agagtattga tcatggtcaa gccacttgct cccgcatctt
     1261 ctgcagcttt tgcgacagta acgatatcgg tcacactcgg ggttaatttg acataaactg
     1321 gcacttctga ggcttccaca gctgctttca ccacatcata agccaaatct ggatcttgac
     1381 caatcaaaag tccatgatta cagtggtcaa cattgggaca agaaatattg agctcgatag
     1441 cttttacatt agttgccttg gaaatcccat gagaaacagc tgcatactct tgttttgaaa
     1501 aaccagctac attggcaata ataggaagat ttggatattc tctttccagc caaggtagct
     1561 tttcagccaa aacaacctct aaaccaggat tttgcaagcc aattgcattg agcataccag
     1621 caggcgtctc tgctactctt ggagttgggt tcccaaaacg tggttcaagg gttgtcgcct
     1681 tgatcataat agaacctaaa aggtttaaat catagtactt ggcatactct tgtccaaagc
     1741 caaaacaacc tgatgctgga ataatcggat ttttcaaatc caaaccaggt agagacactt
     1801 gtaatcgatt tgtagtcata attttctcct tataatacaa ctgttcctgt gcggaaaaca
     1861 ggaccatctt cacagacgcg ttggctgacc gtctcgcttt ctggtacttt tagaacacag
     1921 gcatagcaag ctcccatccc acaagccata cgagattcca gagataaata ggctcttggg
     1981 tgatcatcaa aggtttgatt gatatacttc atcattcctg gagccccaca cgagtaaaca
     2041 gcatcaaact gactatctaa atcattgata acaacggaaa catttccctt gatgccataa
     2101 gaaccatcat ctgtcgttac aaagacctga ccatactgag ccaattccgt tttcaaaata
     2161 acagcatcct tattagcaaa accgaggact gtcactactt tcactccacg ttcatgcaat
     2221 tccttggcca cctcaagcaa gggtggaaca ccaatcccac caccaacaag gagaacctga
     2281 ttctgctcat caaggtcaga caagtcaaaa ccatttccct gaggccccat cacatcaaga
     2341 gtgtctccct gacttaaggt tgaaaaaatt gcagtcccag ctccctcaat ccgataaatg
     2401 aggtgacact gcttgtttgc cttgtcaata gacgaaattg aaataggacg acgtaagaga
     2461 tgggcatcgt ccggtacacg cagatgaaga aattggcctg ctcgcatggc ttcaaccatt
     2521 tctccttcta ggactaattc aaagattgct ggcgcgattt cctcttgtgc aaccaccttc
     2581 atggtttcca accgaatgac acccaaacgc ttcttacatg tgggattcat aacttttcct
     2641 ccttaaattt taaggggacc agataaagaa aagaccttgc tagtgcaagg cctcagttaa
     2701 aatcgtacaa cacaagagag cacactcaaa aagtctcctc tagaaaattg cactattctt
     2761 ttatctgaca ccttgtgagt ctctctggac tccccttaaa ggttgaattt ttattagtat
     2821 actctttcag ctaaaaaaag tcaagtagaa aacgaatatt ctacttaact tgcacgaaat
     2881 tatttttcac gaatgacttc gaccttatat ccatcagggt ctttgacaaa gtaatagttt
     2941 ggtgtagttc ctggtagacc atttggctca gtcacttcat agccttttgc actgtgttct
     3001 tgatgaagtg cctcaagatc aggtgtactg agggcgatat gggcaaaccc atcaccaacc
     3061 acatacggac cgtgatcgta gttataagtc aactccaact catagtcatc accctcaaga
     3121 cctagataga caatcgtgaa ggcatggtct ggaaaatctc tgcgacgcaa ttctttaaaa
     3181 ccaaaagcat cttgataaaa tgcgattgat ttttcaagat tttctactcg taagcaagtg
     3241 tgtagcattt ttgaagccat atttttctcc tttattttta aaaagactgg acaatcctgt
     3301 tccagtctca tcagttgtta tttaccaagt tttgctttag ctgcatctgc aagagctgtg
     3361 aaagctactg catcgttaac agccaagtca gcaagcattt tacggttaac ttcgatctca
     3421 gccaatttca aaccatgcat caattgtgag tatgaaagtc cgttcatacg agctgccgca
     3481 ttgatacgag tgatccacaa tttgcggaag tcacgttttt tctgacgacg gtcacggtat
     3541 gcatagtagt aagagttcat tacttgttct tttgcagtac ggaacaagat gtgtttagct
     3601 ccatagtaac cttttgctaa tttaagaata cgtttacgac gtttgcgtga tacaacgcca
     3661 cctttaacac gtgccatgtt ttatttcctc caaatatttc ctagaattgt ttacttacag
     3721 tcaagctatt atttcaagcg agtaagcatt gctttgatac gtttgtaatc tcctgaatgc
     3781 accatagatg ctttacgaag atgacgacgt tgtttcttag tttttccgtg gaaacggtga
     3841 gaagtgtaag cacggaaacg tttaagtcca ccagaacctg tacgtttgaa acgtttagct
     3901 gatgcgcggt gtgttttttg ttttggcatg attttttctc ctttatttaa ctttctgaca
     3961 attatttttt gtcagtcgct ggcgccaatt gcatgaacat ttgacgtcca tccattttag
     4021 cacgttgttc gatgatggca atatcttgag ttgcttcagc aaactcggct aaaacttttg
     4081 caccaatctc tttatgggta atcatacgac ccttaaagcg aatagatacc ttaactttat
     4141 ttcctttttc aaggaactta cgtgcattgc gaagttttgt atcaaagtca cccttgtcaa
     4201 ttgttggact tagacgaact tctttcacag taacaacgct ttgtttttta cgttgttctt
     4261 tttgcttctt ctggtactca aatttgaact taccgtagtc cataattttt gcaacaggcg
     4321 gtttggcttg gggttgaatc aatactaggt caacattagc gttatcagcc aaagcttgcg
     4381 cttcactgag tggcttgatg cctagctgtt ctccttcaag accaatcaag cgaacttcac
     4441 gtacacgaat ctcatcattg atgaataagt cttgctttgc tatggttttc acctcttttg
     4501 ttttattaga gaaaaacaat agcggactcg taaatataca agcccgcacg ttatgatagc
     4561 gtttcttcga aacttttcat ccgtagggcc aggcaactta atgtcacaag gcgagaagct
     4621 ctcacttctg cttttctcaa cttctatatg ataccaagtt ttctagctct tgtcaagata
     4681 aaaagttatt ttttgaaaag tttgtgtttg tgtttgtatt ttggtttggt tttcgaatca
     4741 aaaagagaga atcaagttga ttccctctct atgttagttt ttccttaact tccttataag
     4801 aatgctaaga cctattaaaa acttcctttt tacgtgaact tccccagctt tcgataaata
     4861 gaatccccac tagcaaaagg ataatcaggc aaggaagtaa gaccatcccc atgctccaat
     4921 ttagatcgac attatcaatc tgcttagata atcttccaga taaaatctcc actgaacgca
     4981 agtaagtaaa gggaatcaga tgtgcaatcc tttgaagagg ctgaattgtt tggatgccaa
     5041 acaataagcc aacaatccca atgagtgaaa gaaagaggac aggcattttt tgcttgaaaa
     5101 agtaagcaat caagtacaca acttccacaa tgacgataaa ggctaagaaa gctaagagca
     5161 agccaggaaa taatacatct tgtattttcc caatagttac ttcttgattc actaagctat
     5221 aaattgggta gggataatct aactgtccaa aaccacttat cagacttccc actagaaaag
     5281 aaaagccaca gattccgata aacagcacag ttacatatcc cactccaact ccaagagagg
     5341 atattgcaaa tgtcactttt gaaacaggat ataagtgagc tgtgtccaga tgattttgat
     5401 atctttctgc aaatagttgt gttagcataa aaataatcgc aaccacaaac aagcttggga
     5461 tgataacctc taaaatccag acaatctgat caatcccgtg ggtcggaaac tccaaagtat
     5521 gtgcttttat gttcaaggga tacagggctt ggtaaatctt ccgttcgcgg tcaaccccca
     5581 tttttaagcc agagctagca gtcgggtcat ttgatacaaa ttcataattc ttctcttcat
     5641 cttgccactg cagatagtag gcttctttcc agcgcccttc ttttagtaaa gttagaattt
     5701 ctgtctttcg cgtcaaaaga tttttttgca cgtctaaatt atttttagca aactggtatt
     5761 cctccgagct ggtatcagac atttgggaga gtttctcttc attttcattg atagccctct
     5821 cgttggctgc aatgcgactt tccaacctgc tctccaagct gtgtgagttt gcagtctgac
     5881 tatttaaata aaaggtaaca ccgagtacag atgcaaataa aagtaagata atccagttta
     5941 aacgactttt gaaaactttc tttaacaaaa atagactaac atctttcata aactaaacct
     6001 cttctatctg cccctgatga atggttacta ctctatcgca gacatcaacc aactcttcct
     6061 tatagtggga acttaaaaga accagctgtt cttgtctatc gatttgtgct agcctatcaa
     6121 aaaacttctg tcgataatac tcatctaagc catttgtaat ctcatccatg agccagcatt
     6181 tggcctgact gaggaaatac atggcaatca ccaagcgttg cttcatgcct aaggaatact
     6241 tgcgaatggg aagactgata tagtcagaca tttcccaata ggcgatttca tccctcaagt
     6301 tcagacctga cttccagatg tttttgataa gacgaaggta gtccatccca cttaagtttc
     6361 catccagcca ttcaatactc tcataataaa ataaagaagg aggggctgcg atatttccac
     6421 tacttatggg aattaaattg ctaatggcac ggaacagggt cgtctttcca gagccattga
     6481 tagcaagaag accataaacc ctaccctttt taaaggtgaa atccacatct tgcaagatga
     6541 cttgtcgcgt ttttaaggtc acatgagtaa gctgcaacat atctagccct cctttttctc
     6601 actctttaag aattaatagc ctccgctgta atagtttatg acctcataac gaccgtagtt
     6661 ccagcctccg ccaactttat actcagaata gctgtcataa cgagaccatg acggaatcca
     6721 agcatactga tggtcgtgat agttggtact atattcccaa accgtattcc aatcatactt
     6781 gtaactttta gtgactgtca cagcagatac actggactga agaagaccaa tagattataa
     6841 actaactaat taaacgattt ttgctaattt ttaatgattt tatatcctca atattgaata
     6901 cgttttcatt ataccatttt tatcattatt atgcaacaaa tttttagttt atttcactaa
     6961 tctacaacat ttatccttcc tatcgaacac tttcgatttt ccaactatcc acccccttaa
     7021 aacgtatagc tccttgctgg tcagttcgat aaactttgct attgatacct tccagtcgtg
     7081 tcaatgtttc ctgatggggg agtttcattc gattgctctt tccaactgag ataagagtaa
     7141 gctctggttt gagtttttct agaaaggctg gacttgatga ttttttattt ccttgttggc
     7201 tagctttcaa aacatttact ttcaagtctg gatagtgctt cagcaagtcc ttctctcctt
     7261 tctcctccaa atttcccgtg aagagaaatt gcttatccaa gaatttccca tacagaacta
     7321 gggtatcatc gtgtcctcca tctcccattt tccttggaga tagaacttct aactgacttc
     7381 caaaaatggg caagttctcc cctactgtca tactacgcac ctttgtttga gtcgcctgta
     7441 gttctgccac aaattccttc tgtttcagac tgtcttttga tactagaatc tcccctacat
     7501 ggaaagcctt ggtcacctct gacaaatctc caacattctc cttgtccgtg ttagtcaaaa
     7561 ttagctggtc aatcttagct actcctcgac ttttgagata gggaatcaag gttcgctggg
     7621 cattgctggt cgtcatcttt tcttgccatt tttcgatttt cttataagat tctgccttac
     7681 cacctacatc tatgagaatg gttttcccag ttacatcccg taggaaaata ctttctcctt
     7741 gccccacatc cagcatggtg atttcatttt ccagtggata cttggtaagg aaaaagagac
     7801 ctgtaatcaa taaactcaat actgttaatc ctttaatgtt tttcctcaaa tcatagacca
     7861 aagccaagga aattaacaat aagattaaaa gccatgcgtt gggttgacca aagacaagcg
     7921 gtctccttgc cacctgcgag accaagcgaa taatgccctc taaccattca aagataaagt
     7981 tcagctgaat gactggatag agaaaggaaa ggacaaataa gatagacaag agcggtaaga
     8041 agaccaagtc aaaaagaaag gaaaagacaa aggtcaaaag gatagaccaa ggttgaaatt
     8101 ccgcaaaata gaaggataga atgggcaata tgcccaagga gatgactaga ctttcactag
     8161 taacagcctt gagcccctcc ccttctttgc tggtcatggt caggataaaa gcataagcac
     8221 aggacaagac tcctcctgct gtcaagaaaa agtttggcat gacaataaag aggacaagca
     8281 ccgtcaaggc aaaattatcc aagcccttaa ccccatgttg agccagtagc ttttgcaaga
     8341 gactgcgaat aaccgatgct gaaaatccag ttagtcccgc atagataagg gaaaagggat
     8401 aagtcagcca cttcaacttt tcttgtgtca agcccaatcg taaaagtagt ttcttaaatc
     8461 cgtccatgaa aaaccctacc tgcatacctg acaaggcaaa aaggtgaata attcctaaac
     8521 tggaataaag ctcattcatc tcctcaaaat cggtgtccag atgtcctagc aagagtcctg
     8581 tcatgtaatt gcgcataggg tctgggaagt gcatcttaat ccaaaccaca gcctttcgac
     8641 gtaaactgga caggttttca cctatatccc aactgccaac cttttggaat gactggattc
     8701 ttttaatatt gagtgtctgg taaattccct gagtcttcag atagccttgg tagtcaaagc
     8761 caccaaaatt tctctgccct tctggctccg aaagcttccc ttctagtcct atctcatgaa
     8821 ggtcagttaa agcttgaaag gcttctttct cctcctcgga ctggagttta taatagactt
     8881 ggaaagcacg accatcagac ttaccacgaa aggacagact gtcaccgtta accttaatag
     8941 tgtctggtaa aatccgtacc ctttcaacag aatccaccaa attttgactc acttgactct
     9001 gttgccaagt ttgaaacaga aaccagaagc caaagactcc acaaatcact agaactttac
     9061 ctgctgattt ccaaggaaat tggataaaga ggcagactag cagaaaaaca aaacccaaca
     9121 aagcaaaata ggatactgag aaaatggcgt agtaaagcca tagtaacaga aaactcaggt
     9181 aaattagggg aatagagaaa ttcttaatcc actgtaacat agtctttaag tttttctatg
     9241 gtcttggcac caatgccaga gaccttcttg agctcgtcta ctgacttgaa cttgccattt
     9301 gcctcacgat ggtcaataat gtcctgagct cgttttcctc ccagtccctt gacctgcttg
     9361 agttcttcca gactggcctt gttgagattg accttctttt ccttgcttgt tgaagaagct
     9421 gtccccgaac cagtctgttg actaactgct tcttctccct tagtaggaac gtaaaccaga
     9481 gcctcatcac taactttctg agctagattg agcgacttgc tgtctgcttg ctctgtcaag
     9541 ccaccagcct tctgaacagc atcattgact cgactaccta caggcaagtc ataaatccct
     9601 ggcgatttga cagcaccttt gacatctact gtgattagat cttgttcaac tggttcttcc
     9661 ttctcttcct tgttcacttc ctttccggtc gatgagtcct tggaaacagc tgcaacttca
     9721 gcctgcaaat tcgtctcttt gacagatgtt tgtggagctg gctttagcag gaaaaatccg
     9781 cctacaagca agcccagacc agtacagatg acgatgattt tatactcttt gattttctcg
     9841 ataattgctt ccatattttc tcctctctta gattattcgt aagaggaaga aaaaacagtc
     9901 gaaaaatttc ttttcaactg cttatttatt tgcaaaatag tcttccttgg tcaagacata
     9961 atgaactctt gtcacgattc ggcctttttc atgctggtcc atacaagcat atggttctgc
    10021 atgggaaaaa cgcatgcctg atttctccat gacctttcct gacgcgggat tagccttatc
    10081 gtgaagggca gtcaacttat tcatccctat cttctcaaaa gctagctcaa tcacagcacg
    10141 attggcttct gtcgttaatc cttgattcca atacttttta ttgataatgt agccaatagc
    10201 tgccttctta agaacaggat caatcttgtg taagtcaata gttccgataa acttgccgtt
    10261 atcttttaat tcaatccccc aacgtcccaa gggattagcc aagtagaact gagcaatgtt
    10321 attcttggtt tcttccaagc tttgattggt tggaaaagtg taacgtgtat tacccttgtc
    10381 cgaggcatag tcaaacattg cttccgcatc atccaaagtt acaggtctaa gcaataaacg
    10441 ctccgtttct atagacggat actgggcaaa tttcacaaat attgattcca tacttttccc
    10501 tccattagag cttgattttc actagtctag cataaaaaaa tttggatgac aagtttttct
    10561 tgatttttga agcggtttca tatacaatga aaccgtcaca tttttgattt atgaactgga
    10621 atgtgacaac caaaacaaga ccgtcaattg aaaggtaggt tatctcaatg ttaatcggaa
    10681 tcccatatga aattaaaaat aacgaaaacc gtgtcgccct cacacctgca ggtgttcata
    10741 gcttagttag tcgtggtcat cgtgtcctta tcgaaacaaa tgctggtctc ggttctggct
    10801 ttactgatgc tgactatcaa aagcaaggag ctgagattgt cgctactgct ggtgaagctt
    10861 gggcagcaga gttggttgtg aaagtaaaag aacctttaag ttctgaatac ggttacttgc
    10921 gcgacgatct tcttctcttc acctacttgc acatggccgc tgctccagaa ttagcagatg
    10981 ctatgttagc agcaaaaaca acaggaattg cctatgaaac tgttcgtgac aatcaaggac
    11041 aactaccgct cctcgttcct atgagtgagg ttgcaggtcg tatggctgtt caaatcggag
    11101 ctcacttcct tactaagcaa gctggtggct ctggtgttct acttggtggt gtaccaggtg
    11161 ttccaaaagg aaaagtaact atcatcggtg atggtgtcgt cggtacacat gctgcccgca
    11221 tcgcccttgg tcttggtgct caagtgacta ttttagatat tagtgccaag cgtctctcag
    11281 ttctagaaga agtctttgga agtcaaattc aaactattat atctaattca ttcaacattg
    11341 aagcaagtgt gagagatgct gatgtggtga ttggagccat tctcatccct ggtgcaaaag
    11401 caccggaatt ggtgacagat gagatggtca aacaaatgcg tccaggctct gtatcgttga
    11461 cgttgctgtt gaccaaggtg gcgttatcga aacagctgac cgtgtgacaa cgcacgatga
    11521 acccgtctat gaaaaacacg gtgttctcca ctatgccgtt gccaatatcc ctggtgcggt
    11581 tgcccgcact tcaaccatcg ccctaaccaa tgtcactctt ccttatatcg aagctttggc
    11641 tggcaaagga ttcgcacaag caatctctga agatgaaggc ttgcgtcaag gtgtgaccac
    11701 ttatcaaggt tacttgacta gcctaccagt tgctcaagga cttaatcgtg actacactga
    11761 tatcaatgat ttagtataaa ttttgaaaag aaaagggtga cttcgcaagt cctacccact
    11821 gtgctttgtg tcatcagcta ttacatcgtt ggtttattgt actgtatact ttgcaactgg
    11881 agactttcgt tccagactca attgtgcata agaaactcta aattgaataa agtcaacaga
    11941 gtttcgccca accacttcgt cttgtaatga caattatata aaccaaagga agctgagctc
    12001 tttagtccca gcttcttttt atatataaaa ttttacccgt gcaaagacag ggccttagca
    12061 gacttctttt ttacttcgtt cacccttgct ttttcttttt aggtttgggc gttggcagtt
    12121 ggttatacat agctaaaatc aggtcttata gaaacatctt attatcaagt tcttccactc
    12181 aaatcatttc tttggcacct ttgtatggaa actcaaaaga agattggtca atcttatcta
    12241 agactgcttg cacgggttta actaaaaagc gatcgtcata aatgccgcca ataatcttgc
    12301 cgcggaagta aagaatatac tccccaatca tggaacggta agtcacatca tctaatcctg
    12361 ataattgttc caaaacaaat tccaaatagt tcttacttga tgccatttct aatcttctag
    12421 gctctgttca gcgataacaa ccgtatagag ttcttgctta acctcgcatc caattgattt
    12481 aaagccctgc ttttcccaaa aatgctgaga ttgcggattt cccttaacat aagccaaacg
    12541 tgcctttcga aagttcttag caaaataagc tagtgcttct gtcacaatat gactaccaat
    12601 ccctttcctc tgataggctt gatcaaccat aaacaaacca ataaaaacag tctcctcatc
    12661 aggatatgca tagacaaaat ccataacagc cacaaggtca gatccattcc aaaatccaac
    12721 aaaaaactta tcagccttag ctttaccttc aggtagacaa agcatgtcct cttttacagt
    12781 tgcaaaattt ggctctggtg gacaatgctg aaaatacaga ggattacttt catataaaga
    12841 taaaatactt ggaatatcct tttcagttag tatcctacaa ctgtaatact tagatagttg
    12901 gtcaatcatc ttttcaaatt cctactttct tgcgccctgt gattatgaca caggaagatg
    12961 cactgatcgt catcagccac ataaaagttc tttccatcgt gcctaatcgt tgtctcaaac
    13021 ctttagccta tacaactgga ttttcctctc tcaaaagtat attcttttgc aggcgaactt
    13081 cctcaaaatc agtcgtgtgc aacttcagta gaatattcat aggctcggat aatctgagcg
    13141 acaactggat ggcgaaccac atccttggct gaaaaatgaa caaagtcaat ctgatggatg
    13201 ttcttgagtt tatcttgagc atcaatcaaa ccggacttga cattacgtgg caggtcaatc
    13261 tgactgatat ctccattgac aatcatctta gaatgaaagc ctaaacgcgt caagaacatc
    13321 ttcatctgca tgatggtcgt gttttgcgcc tcatcgagaa tgacaaaggc atcatccaag
    13381 gtccggccac gcatataggc aaggggcgca atttcgataa tttcacgctc catgagacga
    13441 gtcgtttggt ctttcccaag aatttgatac aaggcatcgt aaacaggacg aaggtaagga
    13501 tccaccttct ccttaagatc acccggaaga aatccaagac tctctcccgc ttccaccgct
    13561 ggacgagtta ggataattcg cttgacttgc ccacgtttaa gggcagtcac tgccaaggtc
    13621 actgcaagga aggtcttccc tgtacctgct ggcccaattc caaaggtcac atcatgctgt
    13681 ttgacactgt ccacataaag tttttgacct aaggttttga cgcggatagg cttcccagta
    13741 ttatccttga tgatttcttc ttcgtaaagg gcgacaaact tgtcaatttc atcatttttg
    13801 accatactaa tagccgtcac tacatctggc gtaccaacgg tcatcccacg atttaccaag
    13861 gccatgagag cttgaataac ctgacgggct tcctcgcaag cagactcttc tcccaaaacc
    13921 tggacaatct ccgtacgagc atgaatcaca acatcaagct cttcttccat caaacgaaga
    13981 tggcgttcat tggaaccaaa aagatgaaac aggtcatctg gatgactcag ttgaatgtct
    14041 attgaatgtt ccttcaaata aagaacctct ctaatccttt tatttctttt tattatagca
    14101 gagggatgga gaaattacta gcccaaaccc aatgaataaa tgctagtgtt ctagatattc
    14161 ctgccaaatg ctgtcaaaat ctcctaggtt aaaagagaaa ctggcatgct cctccaaaaa
    14221 gcgactgacc tcatcaaaat catctgtatg ttttggaaaa gctgcctctt caaaagcgag
    14281 gtctgccaaa attgctttgg gattgttact tttaggattg cgctcggtca tgagccaagt
    14341 gtaaaatgat tttctcataa gcctccctaa atcaactctg taccaaactg gtcctgcttg
    14401 attttaccag ccttcataag accacctaaa gctttcttga actgaccttt agaaatgcca
    14461 aaggttgcct tgatgtcgtc tggagatgac ttgtcattta aggtcatgaa accgccattg
    14521 ctttccaaat aagtcaaaat catctgagca tcgttttcca acatttcaaa ggagcgtggt
    14581 ttgagggaga ggttcaaagt gcggtccact tcacggaaac caataacgcg cgcatctaat
    14641 acttgcccca aacgtggctc tgcgtaacgc tcgctaggat gaataaaacc aagcatatta
    14701 ttttctggta ggtaaacaaa agttcctgat agcttgagac ggtaaacaat ggctggccag
    14761 ttttggttct gcatgttgtt gtaggcagga cgagcaagac gttggaagtc ttcttgataa
    14821 gccaagagac cccagatacg gtctttctta tccacttcaa gacggatgta gagttggtcg
    14881 cccttcttag gccagagttc cttgagctca gggagaatat cgagtgacac aacgatttcc
    14941 ttgtcaggaa ggcctgtatc cacaaagaca cccaagtcct tacgaacctc tgtgacacgt
    15001 ccccaaccaa attggtcctg agtggcagtc acttctaagc ttgtcaggcg gagtttttgc
    15061 ttcatatccg tgtatgcaaa acctttgacc gtatccccta ctgtatgttg gccttcttcc
    15121 ttagcaagag cataggtttg accatccttt tgcacaaagt aaaaacggtc gttttcatcg
    15181 atgatcagtc caacgataaa acttgcaaga tttgtattca tatttccttc tttcgaataa
    15241 aactcagcca gcaatgccaa ctgagttttt ctgtttattt ttagacttcc aaaagttctt
    15301 tctctttgtt ggcagtcata tcgtcgatgt gtttaacagc atcgtctgtt actttttgaa
    15361 tgtctttttc aagagtcttc aattcgtctt cagtgatttc ttttgctttt tcttgtttct
    15421 tagcttcgtc catagcatcg cgacggatat tgcggacagc cactttagca ttttcgccga
    15481 ccttcttcac ttctttagca aggtcacgac gagtctcttc tgtaagagct gggacaacca
    15541 agcgaatcac agaaccgtca ttagctggtg tgataccaag atcagaagcg ttcaaggcac
    15601 gttcgatgtc tttcaatgaa gacttgtcaa atggtgttac caacaaaaca cgcgcttctg
    15661 gaatcgtaat tgaagcgatt tggttaagag gagtttcaac tccatagtat tctacatgta
    15721 tacggtcaag caagcttgca ttggcacgac cagcacggat accaccaaat tcacgagcaa
    15781 gtgattggtg agactgggtc attctctctt tagctttttc aataattgcg ttagccatat
    15841 tctttcttat tccttttctt cgatattatt tgaaactgtt gttccgatat tttcaccaaa
    15901 tacgacacgt ttgatgttgc ctgattggtt catgttgaag acaaccaagt caatgtcgtt
    15961 gtccattgag agggttgaag ctgttgagtc catgatacga agacctttat tgataacgtc
    16021 acggtgggtc aattcttcaa acttaacagc tgtcttatct ttcttaggat cggcattgta
    16081 aacaccatcg acaccatttt tagccatgag gatggcatcc gcttcgattt cagctgcacg
    16141 aagggccgct gttgtatctg tcgagaagta tggtgaacca attccagcac caaagataac
    16201 gatacggcct ttttcaaggt gacgaagggc acgtccacgg acataaggct ctgccacttg
    16261 ttgcatagca atagctgttt gtacacgcgt atcaacccca acttgttgca atgaatctgc
    16321 catcacaaga gcattcataa cagtcccaag cattccagtg taatctgcct gaacacggtc
    16381 catacctgct tctgctgcag gttctccacg ccagagattt cctccaccaa taacaagggc
    16441 aatttcgata cctaagctat gaacttcttg aatctctttt gcgattgttt gaactgtttg
    16501 gatatcaatc cctacgccac gttcaccggc aagggcttca cctgataact tgattaaaat
    16561 acgtttatac ttgggattcg ccattttcac tctccttctt tcatcctacc tattttatca
    16621 caatttctaa gatttttata gtatcatgaa caattctttc aaaaaaatta gacagtcaaa
    16681 aattcctcta agtcggcaag ggcacgctct gcaatttttt cataacgagc cttcttatca
    16741 cggatacgct cgccttccaa ctccttgatg atcccaaaat tgacattcat tggttggaaa
    16801 tgtttgctgt cggcatgggt aatgtaatga gctaagcttc caatcgctgt cgtctcgggg
    16861 aaaataacct cgctttcttc cttgaagaga cgagctgcgt taattcccgc aactaagccc
    16921 gaagccgccg actcaacata gccttccacc cccgtcatct gaccagcaaa gaagagattt
    16981 ggttgtttct tggaacggta agtctgctca agaagatttg gtgaatccat gtaagaattg
    17041 cgatgcatga caccataacg gacaaactcc gcattttcaa gacccggaat catttggaag
    17101 acacgctttt gttctcccca tttgaggtgg gtctggaaac caacaatatt gtataggcta
    17161 ccagctgcat tatcctgacg aagttgcaca accgcataag gtgttttaaa ttctccatca
    17221 cgaggtcctg tgtagtcgtc cggatactca agaccgactg gcttcatagg gccataaagc
    17281 atagttttaa tgccacgttt ggccataact tcgattggca tacatccttc aaagtacttt
    17341 tctttttcaa aagaattgag cggtgcttct tccgcattga ccaaggcttc atggaaatcc
    17401 ataaactctt gcttggtcat tggagcattg agataggctg cttctccctt atcataacga
    17461 gatttgagat agaccttact catatcgata gtgttgacat cgataatagg cgctgctgca
    17521 tcgtagaaat agaagccatc gccattatta agggcatgaa tcttttcagc cagggcatcg
    17581 ctagtcaagg gaccagtcgc cacaactgta ataacatctg ttggcaattc tgtaatttca
    17641 tcacgcacca cttcaatcaa ggggtggttg accacttttt cggtcaccat ttgagagaaa
    17701 ccatcacgat ccaccgcaag ggctccaccg gcaggaacac gtgtagcctc agcagattcc
    17761 aagataacag aacccaagcg acgcatttct tccttgagaa gaccaactgc atttgtcaaa
    17821 gcatccccac gcaaagaatt ggaacaaacc aactcagcaa aattgtctgt tttatgctgg
    17881 ggtgtagact tgacaccacg catttcatat agtttaactg gaataccacg ctctgcgatt
    17941 tggtaagctg cttcagaacc tgccaaacca gcaccgataa cattgatata agattgagac
    18001 acgacactaa tacctctttg ggagtgtgaa gttaagattc acattgaaaa agccaatcag
    18061 acttacaagc tttcgagttt cttggctcag gctgaaaaag tccattggac ttacttcgct
    18121 ctcgaatttc ttggctca
//
LOCUS       DAVBOD010000043        18101 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 640-05
            SAMEA1012484-rid20186543.denovo.043, whole genome shotgun sequence.
ACCESSION   DAVBOD010000043 DAVBOD010000000
VERSION     DAVBOD010000043.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012484
            Sequence Read Archive: ERR059358
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 18101)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18101)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979948.1
            Genome Coverage       :: 595x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:03:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,266
            CDSs (total)                      :: 2,219
            Genes (coding)                    :: 2,091
            CDSs (with protein)               :: 2,091
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 71 of 128
            Pseudo Genes (incomplete)         :: 50 of 128
            Pseudo Genes (internal stop)      :: 33 of 128
            Pseudo Genes (multiple problems)  :: 22 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18101
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012484-rid20186543.denovo.043"
                     /strain="NIG 640-05"
                     /db_xref="taxon:1313"
     gene            3..308
                     /locus_tag="VQ862_001532"
     CDS             3..308
                     /locus_tag="VQ862_001532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000590575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HET3115854.1"
                     /translation="MIKILAACGAGVNSSHQIKSALEEELSNRGYDVHCDAVMVKDVN
                     EDLMKGYDIFTPIAATDLGFEPGIPVIEAGPILFRIPAMSAPVFDNIEAAIKEHGLS"
     gene            356..1831
                     /locus_tag="VQ862_001533"
     CDS             356..1831
                     /locus_tag="VQ862_001533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000338710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
                     /protein_id="HET3115855.1"
                     /translation="MDAIFDLIGKVFNPILEMGGPVIMLIILTVLALLFGVKFSKALE
                     GGIKLAIALTGIGAIIGMLNGAFSASLAKFVENTGIQLSITDVGWAPLATITWGSAWT
                     LYFLLIMLIVNVVMLAMKKTDTLDVDIFDIWHLSITGLLIKWYADNNGVSQGVSLFIA
                     TAAIVLVGVLKIINSDLMKPTFDDLLNAPSSSPMTSTHMNYMMNPVIMVLDKIFEKFF
                     PGLDKYDFDAAKLNKKIGFWGSKFFIGFILGIVIGIMGTPHPIAGVADADKWRLVIKG
                     WLSLGLTAGVSLELFSLIGSWFIAAVEPLSQGITNVATKRLQGRKFNIGLDWPFIAGR
                     AEIWACANVLAPIMLIEAVLLSKVGNGILPLAGIIAMGVTPALLVVTRGKLLRMIIFG
                     TLLLPLFLLSGTLIAPFATELAKGVGAFPEGVSQTQLITHSTLEGPIEKLLGWTIGNT
                     TTGDIKAILGAVAFLVFYIGIFAWYRKQMIKRNEEYAAKAK"
     gene            1854..1931
                     /locus_tag="VQ862_001534"
                     /pseudo
     CDS             1854..1931
                     /locus_tag="VQ862_001534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            2091..8792
                     /locus_tag="VQ862_001535"
     CDS             2091..8792
                     /locus_tag="VQ862_001535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Ig-like domain-containing protein"
                     /protein_id="HET3115856.1"
                     /translation="MGKGHWNRKRVYSIRKFAVGACSVMIGTCAVLLGGNIAGESVVY
                     ADETLITHTAEKPKEEKMIVEEKADKALETKNVVERTEQSEPSSTEAIASEKKEDEAV
                     TPKEEKVSAKLEEKAPRIESQASSQEKPLKEDAKAVTNEEMNQMIEDRKVDFNQNWYF
                     KLNANSKEAIKPDVDVSTWKKLDLPYDWSIFNDFDHESPAQNEGGQLNGGEAWYRKTF
                     KLDEKDLKKNVRLTFDGVYMDSQVYVNGQLVGHYPNGYNQFSYDITKYLHKDGRENVI
                     AVHAVNKQPSSRWYSGSGIYRDVTLQVTDKVHVEKNGTTILTPKLEEQQHGKVETHVT
                     SKIANTDDKDHELVAEYQIVERGGHAVTGLVRTASRTLKAHESTSLDAILEVERPKLW
                     TVLNDKPALYELITRVYRDGQLVDAKKDLFGYRYYHWTPNEGFSLNGERIKFHGVSLH
                     HDHGALGAEENYKAEYRRLKQMKEMGVNSIRTTHNPASEQTLQIAAELGLLVQEEAFD
                     TWYGGKKPYDYGRFFEKDATHPEARKGEKWSDFDLRTMVERGKNNPAIFMWSIGNEIG
                     EANGDAHSLVTVKRLVKVIKDVDKTRYVTMGADKFRFGNGSGGHEKIADELDAVGFNY
                     SEDNYKALRAKHPKWLIYGSETSSATRTRGSYYRPERELKHSNGPERNYEQSDYGNDR
                     VGWGKTATASWTFDRDNAGYAGQFIWTGTDYIGEPTPWHNQNQTPVKSSYFGIVDTAG
                     IPKHDFYLYQSQWVSVKKKPMVHLLPHWNWENKELASKVADSEGKIPVRAYSNASSVE
                     LFLNGKSLGLKTFNKKQTSDGRTYQEGANANELYLEWKVAYQPGTLEAIARDESGKEI
                     ARDKITTAGKPAAVRLIKEDHAIAADGKDLTYIYYEIVDSQGNVVPTANNLVRFQLHG
                     QGQLVGVDNGEQASRERYKAQADGSWIRKAFNGKGVAIVKSTEQAGKFTLTAHSDLLK
                     SNQVTVFTGKKEGQEKTVLVTEVPKVQTIIGEAPEMPTTVPFVYSDGSRAERPVTWSS
                     VDVSKPGIVTVKGMADGREVEARVEVIALKSELPVVKRIAPNTDLNSVDKSVSYVLTD
                     GSVQEYEVDKWEIAEEDKAKLAIPGSRIQATGYLEGQPIHATLVVEEGNPAAPAVPTV
                     TVGGEAVTGLTSQKPMQYRTLAYGAKLPEVTASAKNAAVTVLQASAANGMRASIFIQP
                     KDGGPLQTYAIQFLEEAPKIAHLSLQVEKADSLKEDQTVKLSVRAHYQDGTQAVLPAD
                     KVTFSTSGEGEVAIRKGMLELHKPGAVTLKAEYEGAKGQVDLTIQANTEKKIAQSIRP
                     VNVVTDLHQEPTLPSTVTVEYDKGFPKAHKVTWQAIPKEKLDSYQTFEVLGKVEGIDL
                     EARARVSVEGIVSVEEVSVTTPIAEAPQLPESVRTYDSNGHVSSAKVAWDAIRIEQYA
                     KEGVFTVNGRLEGTQLTTKLHVRVSAQTEQGANISDQWTGSELPLAFASDSNPSDPVS
                     NVNDKLISYNNQPANRWTNWNRSNPEASVGVLFGDSGILSKRSVDNLSVGFHEDHGVG
                     APKSYVIEYYVGKTVPTAPKNPSFVGNEDHVFNDSANWKPVTNLKAPAQLKAGEMNHF
                     SFDKVETYAVRIRMVKADNKRGTSITEVQIFAKQVAAAKQGQTRIQVDGKDLANFNPD
                     LTDYYLESVDGKVTAVTASVSNNGLATVVPSVREGEPVRVIAKAENGDILGEYRLHFT
                     KDKSLLSHKPVAAVKQARLLQVGQALELPTKVPVYFTGKDGYETKDLTVEWEEVPAEN
                     LTKAGQFTVRGRVLGSNLVAEITVRVTDKLGETLSDNPNYDENSNQAFASATNDIDKN
                     SHDRVDYLNDGDHSENRRWTNWSPTPSSNPEVSAGVIFRENGKIVERTVAQGKVQFFA
                     DSGTDAPSKLVLERYVGPEFEVPTYYSNYQAYDADHPFNNPENWEAVPYRADKDIAAG
                     DEINVTFKDIKAKAMRWRMERKADKSGVAMIEMTFLAPSELPQESTQSKILVDGKELA
                     DFAENRQDYQITYKGQRPKVSVEENNQVASTVVDSGEDSLPVLVRLVSESGKQVKEYR
                     IHLTKEKPVSEKTVAAVQEDLPKLEFVEKDLAYKTVEKKDSTLYLGETRVEQEGKTGK
                     ERIFTAINPDGSKEEKLREVVEAPTDRIVLVGTKPVAQEAKKPQVSEKADTKPIDSSE
                     ASQTNKAQLPNTGSASSQAAVAAGLALLGLSAGLVVTKGKKED"
     gene            complement(9040..9896)
                     /locus_tag="VQ862_001536"
                     /pseudo
     CDS             complement(9040..9896)
                     /locus_tag="VQ862_001536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270419.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(10107..10466)
                     /locus_tag="VQ862_001537"
     CDS             complement(10107..10466)
                     /locus_tag="VQ862_001537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004249826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3397 domain-containing protein"
                     /protein_id="HET3115857.1"
                     /translation="MGMILMKLASILLLILTLVICIILTKLFRLKKLGRNFADLAFPV
                     LVFEYYLITAKTFTHNFLPRLGLTLSILAIILVFFFLLKKRSFYYPKFIKFFWRAGFL
                     LTLIMYVEMIVELFLMK"
     gene            10558..11514
                     /locus_tag="VQ862_001538"
                     /pseudo
     CDS             10558..11514
                     /locus_tag="VQ862_001538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002881980.1"
                     /note="This family includes YhcC from E. coli K-12, an
                     uncharacterized radical SAM protein.; internal stop;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01212 family radical SAM protein"
     gene            11498..12055
                     /locus_tag="VQ862_001539"
     CDS             11498..12055
                     /locus_tag="VQ862_001539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000828405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HET3115858.1"
                     /translation="MKRPLEMAHDFLAEVVTKEDVVVDATMGNGHDTLFLAKLAKQVY
                     AFDIQKQALEKTQERLHQADLTNAQLILQGHETLDQFVIKAKAGIFNLGYLPSADKSV
                     ITRPQTTIEALEKLCGLLVKGGRIAIMIYYGHEGGDLERDAVLDFVIQLNQQEYTAAI
                     YRTLNQVNNPPFLVMIEKLERYRHG"
     gene            12048..12302
                     /locus_tag="VQ862_001540"
     CDS             12048..12302
                     /locus_tag="VQ862_001540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000361102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3115859.1"
                     /translation="MDKQYLHEKLDAMRQNFVESTHHERAVGVLDQAHMSKKMLKIKK
                     KLVALEMERCQRKIEHKDCSKIDQKIKEQKEIFESCCKKD"
     gene            12314..14368
                     /locus_tag="VQ862_001541"
     CDS             12314..14368
                     /locus_tag="VQ862_001541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000421632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation:proton antiporter"
                     /protein_id="HET3115860.1"
                     /translation="MELLIYLILFLLVLIVSSTTNKLLPFLPLPLVQILLGIVIGLFL
                     PNTDFHLNTELFLALVIGPLLFREAEEADVTAILKHWRIIVYLIFPVIFISTLSLGGL
                     AHLLWFSLPLAACLAVGAALGPTDLVAFASLSERFSFPKRVSNILKGEGLLNDASGLV
                     AFQVALTAWTTGAFSLGQASSSLIFSILGGFLIGFLTAMTNRFLHTFLLSVRATDIAS
                     ELLLELSLPLVTFFLAEEVHVSGIIAVVVAGILKASRFKKITLLEAQVDTVTETVWHT
                     VTFMLNGSVFVILGMELEMIAEPILTNPIYNPLLLLLSLIALTFVLFVIRFIMIYGYY
                     AYRTRRLKKKLNKYMKDMFLLTFSGVKGTVSIATILLIPSNLEQEYPLLLFLVAGVTL
                     VSFLTGLLVLPHLSDEEEKSKDYLMHIAILNEVTLELEKELEDTRNKLPLYAAIDNYH
                     GRIENLILSQENQDDQEDWAALKLLILSIESDGLEQAYEEGNISNRAYRVYQRYLKNI
                     EQGINRKLASRLTYYFLVSLRILRFLLHEVFTLGKTFRSWKDKEQSRLRALDYDQIAE
                     LYLANTEMIIESLENLKGVYRRSLISFMQESRLRETAIISSGAFVERVINRVKPNNID
                     EMLRGYYLERKLIFEYEEKRLITTKYAKKLRQNVNNLENYSLKEAANTLPYDMVELVR
                     RN"
     gene            14547..15407
                     /locus_tag="VQ862_001542"
     CDS             14547..15407
                     /locus_tag="VQ862_001542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihY/virulence factor BrkB family protein"
                     /protein_id="HET3115861.1"
                     /translation="MKKWWKELIDKPLLKAFLHYYQASDSELTSVAVAYYWLISIFPL
                     LLVVVNILPYFQIPVGEFLCFMKDVLPPSLYEGVEKIAREVLTQPSTGLLSFSVLSAL
                     WSFSKSMNFLQKAFNKAYGVEKSRGLISHQMLSLLVSFGLQLLFAFALFLILFGQMIL
                     ALLAHYWTKDGIIYQALQGLAGPLIYALLFAILVMLYYFLPNISNRKISYTLPGSAFV
                     LLVILGLLTLFSSYLNYYVHHLVDVRILGSVLLVVMMFWFILIAKIVILGAVINASMQ
                     SLKDPVFKKD"
     gene            15626..16336
                     /gene="ccdA2"
                     /locus_tag="VQ862_001543"
     CDS             15626..16336
                     /gene="ccdA2"
                     /locus_tag="VQ862_001543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000509848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     membrane protein CcdA2"
                     /protein_id="HET3115862.1"
                     /translation="MGHIFFFLSVFLAGILSFFSPCILPLLPVYTGVLLDDKDGAQAS
                     SGKFSISVTSLLRTLAFIAGISFIFILLGYGAGFLGDLLYASWFQYLTGAIIILLGLH
                     QMEILHFKGLYKEKRLQLQGQGQNGKGYSQAFLLGLTFSFAWTPCVGPVLGSVLALAA
                     SGGSGAWQGAGLMLVYTLGLALPFLLLALTSSYVLKHFRKLHPYLGILKKVGGFLIIV
                     MGLLVLFGNASILSQLFE"
     gene            16356..16922
                     /locus_tag="VQ862_001544"
     CDS             16356..16922
                     /locus_tag="VQ862_001544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redoxin family protein"
                     /protein_id="HET3115863.1"
                     /translation="MKKWQTCVLGAGSLLWLTACSGKSVTSEHQTKDEMKTEQTASKT
                     SAAKGKEVADFELMGVDGKTYRLSDYKGKKVYLKFWASWCSICLASLPDTDEIAKEAG
                     DDYVVLTVVSPGHKGEQSEADFKNWYKGLDYKNLPVLVDPSGKLLETYGVRSYPTQAF
                     IDKEGKLVKTHPGFMEKDAILQTLKELA"
     gene            16933..18045
                     /gene="msrB"
                     /locus_tag="VQ862_001545"
     CDS             16933..18045
                     /gene="msrB"
                     /locus_tag="VQ862_001545"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HET3115864.1"
                     /translation="MNDKLKIFLLLGVFFLAITGFYVLLIRNAGQTDASQIEKAAVSQ
                     GGKAVKKTEISKDADLHEIYLAGGCFWGVEEYFSRVPGVTDAVSGYANGRGETTKYEL
                     INQTGHAETVHVTYDAKQISLKEILLHYFRIINPTSKNKQGNDVGTQYRTGVYYTDDK
                     DLEVINQVFDEVAKKYDQPLAVEKENLKNFVVAEDYHQDYLKKNPNGYCHINVNQAAY
                     PVIDASKYPKPSDEELKKTLSPEEYAVTQENQTERAFSNRYWDKFESGIYVDIATGEP
                     LFSSKDKFESGCGWPSFTQPISPDVVTYKEDKSYNMTRMEVRSRVGDSHLGHVFTDGP
                     QDKGGLRYCINSLSIRFIPKDQMEEKGYAYLLDYVD"
BASE COUNT         5445 a         3450 c         3979 g         5227 t
ORIGIN      
        1 aaatgattaa aattcttgct gcctgcggtg caggtgttaa ctcaagtcac caaattaaaa
       61 gtgctctaga agaagaactt tcaaaccgtg gttatgatgt tcactgtgat gcagtcatgg
      121 tgaaagatgt aaacgaagac cttatgaaag gttacgatat ctttacacca atcgctgcaa
      181 cagaccttgg ttttgaacca ggtatcccag ttatcgaagc tgggccaatc ttattccgta
      241 tcccagcaat gagcgctcca gtatttgaca atattgaagc agctattaaa gaacacggat
      301 taagctaatt ctaatttgtt aacattcata taacataaaa aagggaggaa ctgttatgga
      361 tgcaatcttt gacctaatcg gaaaggtttt caatcccatc ttagaaatgg gtggacctgt
      421 catcatgttg atcattttga cagtattggc tttacttttt ggagtgaaat tctccaaagc
      481 gcttgaaggt ggtatcaaac ttgccatcgc tcttacaggt atcggtgcta tcatcggtat
      541 gctaaatggt gctttctcag catcacttgc aaaattcgtt gaaaacactg gtatccaatt
      601 gagtattaca gacgttggtt gggcaccact cgcaacaatc acttggggtt ctgcttggac
      661 actatacttc ttgctcatca tgttgattgt caacgtagtg atgcttgcta tgaagaaaac
      721 cgatacactt gatgtcgata tatttgatat ctggcacttg tctatcacag gtctcttgat
      781 taaatggtat gctgataaca atggtgtgag tcaaggggtt tcactcttta ttgctacagc
      841 agctatcgtc cttgtcggtg tgttgaaaat tatcaactct gacttgatga aacctacatt
      901 tgatgacctt cttaacgccc caagttcatc accaatgaca tcaactcaca tgaactacat
      961 gatgaaccca gttatcatgg ttttggataa gatttttgaa aaattcttcc caggccttga
     1021 taaatatgac tttgatgctg ctaaattgaa caagaaaatc ggtttctggg gatctaaatt
     1081 cttcatcggt ttcatccttg gtatcgttat cggtattatg ggaactccac atccaattgc
     1141 aggtgttgca gatgcagata aatggcgtct tgttatcaaa ggatggttgt ctcttggttt
     1201 gactgccggt gtatctttgg aactcttctc acttatcggt tcatggttca tcgcagccgt
     1261 agaaccacta tcacaaggta ttacaaacgt tgctactaaa cgtcttcaag gacgtaaatt
     1321 caatatcggt cttgactggc cattcatcgc tggtcgtgct gaaatctggg cttgtgccaa
     1381 cgtacttgca ccaatcatgt tgattgaagc agtgcttctt tcaaaagttg gaaatggtat
     1441 cttgccactt gcaggtatca tcgctatggg tgttactcca gctctcttgg ttgtaactcg
     1501 tggtaaattg ctccgtatga ttatcttcgg aacactcttg ttgccactct tccttctttc
     1561 aggtaccctt attgcaccat ttgcaacaga acttgctaaa ggtgtaggtg ccttcccaga
     1621 aggtgtgagc caaactcaat tgattactca ctctactctt gaaggaccaa tcgaaaaact
     1681 tcttggttgg acaattggta acactacaac tggtgatatc aaagcaatcc ttggtgcagt
     1741 agccttcctt gtattctata tcggtatctt tgcttggtac agaaaacaaa tgatcaaacg
     1801 taacgaagag tacgcagcaa aagcaaaata atgcgctcct ataaaatata aactcaatga
     1861 aaatcaaaga gcaaactagg aaactagcca caggttgctc aaaacacagt tttgaggttg
     1921 tagatgaaac tgacgaagtc agtaatcata tctacggcaa ggcgacgctg acgaagtttg
     1981 aattggattt tcgcagagtg taaattgttg aaactaggtt gtcataccat gtataccact
     2041 tgggctttgg tagtagctaa ctgcactaaa tataatataa ggagggtttt atggggaaag
     2101 gccattggaa tcggaaaaga gtttatagca ttcgtaagtt tgctgtggga gcttgctcag
     2161 taatgattgg gacttgtgca gttctattag gaggaaatat agctggagaa tctgtagttt
     2221 atgcggatga aacacttatt actcatactg ctgagaaacc taaagaggaa aaaatgatag
     2281 tagaagaaaa ggctgataaa gctttggaaa ctaaaaatgt agttgaaagg acagaacaaa
     2341 gtgaacctag ttcaactgag gctattgcat ctgagaagaa agaagatgaa gccgtaactc
     2401 caaaagagga aaaagtgtct gctaaactgg aagaaaaagc tccaaggata gaatcacaag
     2461 cttcaagtca agaaaaaccg ctcaaggaag atgctaaagc tgtaacaaat gaagaaatga
     2521 atcaaatgat tgaagacagg aaagtggatt ttaatcaaaa ttggtacttt aaactcaatg
     2581 caaattctaa ggaagccatt aaacctgatg tagacgtatc tacgtggaaa aaattagatt
     2641 taccgtatga ctggagtatc tttaacgatt tcgatcatga atctcctgca caaaatgaag
     2701 gtggacagct caacggtggg gaagcttggt atcgcaagac tttcaaacta gatgaaaaag
     2761 acctcaagaa aaatgttcgc cttacttttg atggcgtcta catggattct caagtttatg
     2821 tcaatggtca gttagtgggg cattatccaa atggttataa ccagttctca tatgatatca
     2881 ccaaatacct tcacaaagat ggtcgtgaga atgtgattgc tgtccatgca gtcaacaaac
     2941 agccaagtag ccgttggtat tcaggaagtg gtatctatcg tgatgtgact ttacaagtga
     3001 cagataaggt gcatgttgag aaaaatggga caactatttt aacaccaaaa cttgaagaac
     3061 aacaacatgg caaggttgaa actcatgtga ccagcaaaat cgccaatacg gacgacaaag
     3121 accatgaact tgtagccgaa tatcaaatcg ttgaacgagg tggtcatgct gtaacaggct
     3181 tagttcgtac agcgagtcgt accttaaaag cacatgaatc aacaagccta gatgcgattt
     3241 tagaagttga aagaccaaaa ctctggaccg ttttaaatga caaacctgcc ttgtacgaat
     3301 tgattacgcg tgtttaccgt gacggtcaat tggttgatgc taagaaggat ttgtttggtt
     3361 accgttacta tcactggact ccaaatgaag gtttctcttt gaatggtgaa cgtattaaat
     3421 tccatggagt atccttgcac cacgaccatg gggcgcttgg agcagaagaa aactataaag
     3481 cagaatatcg ccgtctcaaa caaatgaagg agatgggagt taactccatc cgtacaaccc
     3541 acaaccctgc tagtgagcaa accttgcaaa tcgcagcaga actaggttta ctcgttcagg
     3601 aagaggcttt tgatacttgg tatggtggca agaaacctta tgactatgga cgtttctttg
     3661 aaaaagatgc cactcaccca gaagctcgaa aaggtgaaaa atggtctgat tttgacctac
     3721 gtaccatggt cgaaagaggc aaaaacaacc ctgctatctt catgtggtca attggtaatg
     3781 aaataggtga agctaatggt gatgcccact ctttagtaac tgttaaacgt ttggtcaagg
     3841 ttatcaagga tgttgataag actcgctatg ttaccatggg agcagataaa ttccgtttcg
     3901 gtaatggtag cggagggcat gagaaaattg ctgatgaact cgatgctgtt ggatttaact
     3961 attctgaaga taattacaaa gcccttagag ctaagcatcc aaaatggttg atttatggat
     4021 cagaaacatc ttcagctacc cgtacacgtg gaagttacta tcgccctgaa cgtgaattga
     4081 aacatagcaa tggacctgag cgtaattatg aacagtctga ctatgggaat gatcgtgtgg
     4141 gttgggggaa aacagcaacc gcttcatgga cttttgaccg tgacaacgct ggctatgctg
     4201 gacagtttat ctggacaggt acggactata ttggtgaacc tacaccatgg cacaaccaaa
     4261 atcaaactcc tgttaagagc tcttactttg gtatcgtaga tacagccggc attccaaaac
     4321 atgacttcta tctctaccaa agccaatggg tttctgttaa gaagaaaccg atggtacacc
     4381 ttcttcctca ctggaactgg gaaaacaaag aattagcatc caaagtagct gactcagaag
     4441 gtaagattcc agttcgtgct tattcgaatg cttctagtgt agaattgttc ttgaatggaa
     4501 aatctcttgg tcttaagact ttcaataaaa aacaaaccag cgatgggcgg acttaccaag
     4561 aaggtgcaaa tgctaatgaa ctttatcttg aatggaaagt tgcctatcaa ccaggtacct
     4621 tggaagcaat tgctcgtgat gaatctggca aggaaattgc tcgagataag attacgactg
     4681 ctggtaagcc agcggcagtt cgtcttatta aggaagacca tgcgattgca gcagatggaa
     4741 aagacttgac ttacatctac tatgaaattg ttgacagcca ggggaatgtg gttccaactg
     4801 ctaataatct ggttcgcttc caattgcatg gtcaaggtca actggtcggt gtagataacg
     4861 gagaacaagc cagccgtgaa cgctataagg cgcaagcaga tggttcttgg attcgtaaag
     4921 catttaatgg taaaggtgtt gccattgtca aatcaactga acaagcaggg aaattcaccc
     4981 ttactgccca ctctgatctc ttgaaatcga accaagtcac tgtctttact ggtaagaaag
     5041 aaggacaaga gaagactgtt ttggtgacag aagtgccaaa agtacagacc attattggag
     5101 aggcacctga aatgcctacc actgttccgt ttgtatacag tgatggtagc cgtgcagaac
     5161 gtcctgtaac ctggtcttca gtagatgtga gcaagcctgg tattgtaacg gtgaaaggta
     5221 tggctgacgg acgagaagta gaagctcgtg tagaagtgat tgctcttaaa tcagagctac
     5281 cagttgtgaa acgtattgct ccaaatactg acttgaattc tgtagacaaa tctgtttcct
     5341 atgttttgac tgatggaagt gtacaagagt atgaagtgga caagtgggag attgccgaag
     5401 aagataaagc taagttagca attccaggtt ctcgtattca agcgaccggt tatttagaag
     5461 gtcaaccaat tcatgcaacc cttgtggtag aagaaggcaa tcctgcggca cctgcagtac
     5521 caactgtaac ggttggtggt gaagctgtca caggtcttac tagtcaaaaa ccaatgcaat
     5581 accgcactct tgcttatgga gctaagttgc cagaagtcac agcaagtgct aaaaatgcag
     5641 ctgttacagt tcttcaagca agcgcagcaa acggcatgcg tgcgagcatc tttattcagc
     5701 ctaaagatgg tggccctctt caaacctatg caattcaatt ccttgaagaa gcgccaaaaa
     5761 ttgctcactt gagcttgcaa gtggaaaaag ctgacagtct caaagaagac caaactgtca
     5821 aattgtcggt tcgagctcac tatcaagatg gaacgcaagc tgtattacca gctgataaag
     5881 taaccttctc tacaagtggt gaaggggaag tcgcaattcg taaaggaatg cttgagttac
     5941 ataagccagg agcagtcact ctcaaagcgg aatatgaggg agctaaaggc caagttgatc
     6001 tcactatcca ggccaatact gagaagaaga ttgcgcaatc tatccgtcca gtaaatgtag
     6061 tgacagattt acaccaagaa cctactcttc cgtcaacagt aacggttgag tatgacaaag
     6121 gtttccctaa agctcacaaa gtcacttggc aagctattcc gaaagaaaaa ctagactcct
     6181 atcaaacctt tgaagtacta ggtaaagttg aaggaattga ccttgaagcg cgtgcaagag
     6241 tctctgtaga aggtatcgtt tcagttgaag aagtcagtgt gacaactcca atcgcagaag
     6301 caccacaatt accagaaagc gttcggacat atgattcaaa tggtcacgtt tcatcagcta
     6361 aggttgcatg ggatgcgatt cgtatagagc aatacgctaa ggaaggtgtc tttacagtta
     6421 atggtcgctt agaaggtact caattaacaa ctaaacttca tgttcgcgta tctgctcaaa
     6481 ctgagcaagg tgcaaatatt tctgaccaat ggaccggttc agaattgcca cttgcctttg
     6541 cttcagactc aaatccaagc gacccagttt caaatgttaa tgacaagctc atttcctaca
     6601 ataaccaacc agccaatcgt tggacaaact ggaatcgtag taatccagaa gcttcagtcg
     6661 gtgttctgtt tggagattca ggtatcttga gcaaacgctc cgttgataat ctaagtgtcg
     6721 gattccacga agaccatgga gttggtgcac cgaagtctta tgtgattgag tattatgttg
     6781 gtaagactgt cccaacagct cctaaaaacc ctagttttgt tggtaatgag gaccatgtct
     6841 ttaatgattc tgccaactgg aaaccagtta ctaatctaaa agcccctgct caactcaagg
     6901 ctggagaaat gaaccacttt agctttgata aagttgaaac ctatgctgtt cgtattcgca
     6961 tggttaaagc agataacaag cgtggaacgt ctatcacaga ggtacaaatc tttgcgaaac
     7021 aagttgcggc agccaaacaa ggacaaacaa gaatccaagt tgacggcaaa gacttagcaa
     7081 acttcaaccc tgatttgaca gactactacc ttgagtctgt agatggaaaa gttacggcgg
     7141 tcacagcaag tgttagcaac aatggtctcg ctaccgtcgt tccaagcgtt cgtgaaggtg
     7201 agccagttcg tgtcatcgcg aaagctgaaa atggcgacat cttaggagaa taccgtctgc
     7261 acttcactaa ggataagagc ttactttctc ataaaccagt tgctgcggtt aaacaagctc
     7321 gcttgctaca agtaggtcaa gcacttgaat tgccgactaa ggttccagtt tacttcacag
     7381 gtaaagacgg ctacgaaaca aaagacctga cagttgaatg ggaagaagtt ccagcggaaa
     7441 atctgacaaa agcaggtcaa tttactgttc gaggccgtgt ccttggtagt aaccttgttg
     7501 ctgagatcac tgtacgagtg acagacaaac ttggtgagac tctttcagat aaccctaact
     7561 atgatgaaaa cagtaaccag gcctttgctt cagcaaccaa tgatattgac aaaaactctc
     7621 atgaccgcgt tgactatctc aatgacggag atcattcaga aaatcgtcgt tggacaaact
     7681 ggtcaccaac accatcttct aatccagaag tatcagcggg tgtgattttc cgtgaaaatg
     7741 gtaagattgt agaacggact gttgcacaag gaaaagttca gttctttgca gatagtggta
     7801 cggatgcacc atctaaactc gttttagaac gctatgtcgg tccagagttt gaagtgccaa
     7861 cctactattc aaactaccaa gcctacgacg cagaccatcc attcaacaat ccagaaaatt
     7921 gggaagctgt tccttatcgt gcggataaag acattgcagc tggtgatgaa atcaacgtaa
     7981 catttaaaga tatcaaagcc aaagctatga gatggcgtat ggagcgtaaa gcagataaga
     8041 gcggtgttgc gatgattgag atgaccttcc ttgcaccaag tgaattgcct caagaaagca
     8101 ctcaatcaaa gattcttgta gatggaaaag aacttgctga tttcgctgaa aatcgtcaag
     8161 actatcaaat tacctataaa ggtcaacggc caaaagtctc agttgaagaa aacaatcaag
     8221 tagcttcaac tgtggtagat agtggagaag atagccttcc agtacttgtt cgcctcgttt
     8281 cagaaagtgg aaaacaagtc aaggaatacc gtatccactt gactaaggaa aaaccagttt
     8341 ctgagaagac agttgctgct gtacaagaag atcttccaaa actcgaattt gttgaaaaag
     8401 atttggccta caagacagtt gagaaaaaag attcaacact gtatctaggt gaaactcgtg
     8461 tagaacaaga aggaaaaact ggtaaagaac gtatctttac agcgattaat cctgatggaa
     8521 gtaaggaaga aaaactccgt gaagtggtag aagctccgac agaccgcatc gtcttggttg
     8581 gaaccaaacc agtagctcaa gaagctaaaa aaccacaagt gtcagaaaaa gcagatacaa
     8641 aaccaattga ttcaagtgaa gctagtcaaa ctaataaagc ccagttacca aatacaggta
     8701 gtgcgtcaag ccaagcagca gtagcagcag gtttagctct tctaggtttg agtgcaggat
     8761 tagtagttac taaaggtaaa aaagaagact agaaattttg ataccttctt tatcattaaa
     8821 gaccaaagaa aaactcttgt cctaaataga agataaagag tctggaacaa aatagttctc
     8881 aaccacaaaa aagctagata tttccaattg cggaactcta gctttttaat tttgagtcgt
     8941 tctctgattg tatagtagat tgaaactaga gtagtacact tctacttcta aaacattgtt
     9001 agaaatcgat ttgactgtcc ttatcgattt gtcctgttct tatttgattt cactatgttt
     9061 taggaggtta ttggccataa gtaccaatcc catgtcaatt ctcacttgac gcttgcctct
     9121 cagattacat ctcttgtaac ccaaacaagc ctttatctgc ccaaagacag gttccacatc
     9181 aatcttgcgt tgagcgaaaa tctgtctatc ttggggagat aaaagcgcct gacattcttt
     9241 agctttcaag ttttgatagc gttcgttcat atacagtccc ttttgagggg ctgattcagg
     9301 ttcatcagcg tagtaaacct tgatttcctg ttgaaagtct gtctgtgttt tctggtactt
     9361 gatatggtga aaacgatagc accagccatc aggatgtatg tagctatcct ccttgtcatt
     9421 atagtgccaa ttcgctaagt ttttagctga ctgtttatac cctctctttt gtttcttatc
     9481 aaacatggca tatttaatca gaaggggagt gatttcttct tgaaaataga cttgtatctg
     9541 ttcttgaagt ttggcggaga atttctctgt cgttttcttc cacacaaaac tatacttgtt
     9601 ggcattggct tcaatcttag ttccgtcaat aaacaaacaa tctaaggtca ctaactcttc
     9661 catttttcaa tttttcgacc agagaaaatc ccttgtgaat aggcaaatag aagagtagat
     9721 acaagcattt taaggtgata agacgggcga tcaaaggcat gatagaaggc gtggaaatga
     9781 caatcctcca aggtattcac cactttttca atagtaaaaa cgagatggtc ttgtggcaag
     9841 aaggaactga tttctagtgg taaagttgtt tgatttgtgt tatagtgaat atgcatggga
     9901 tagcctttct aaatggttta ttgtgcaatt ctattttacc aagactatcg caaccatgca
     9961 aaaaagcaac ggcaaatccg ttgctttttt tggagataag agactattgt cccagactct
    10021 tttctttgta taaaattgta tagtgttatt gtctatacta ttttgtagag aaagcaaaaa
    10081 tccctagaaa atgcttaggg attcgactat ttcattaaga acaattcaac aatcatttct
    10141 acatacatga taagggttaa taagaatcct gcacgccaga agaatttgat gaatttagga
    10201 tagtaaaagc tgcgtttttt caaaaggaag aaaaagacga gaataatggc taggatcgag
    10261 agggttagcc ccagtctagg gaggaaatta tgggtaaagg ttttagctgt aatcaagtaa
    10321 tactcaaata ccaagactgg aaaagccaaa tccgcaaagt ttcgtcctag tttttttaat
    10381 ctaaaaagtt tggttaggat aatgcagatg actaaggtca gtatcaataa taaaatagat
    10441 gctaatttca ttaaaatcat acccatattg tatcataaaa aaaggctaat ggaaacgaga
    10501 aacagaggaa tttataagaa agtcaggctt ttgagattgt gggtgatttt tgttataatg
    10561 aaagttataa aatcttataa taccttgaat gattattatc gaaaactctt tggagaaaag
    10621 acttttaaag tccctattga tgcgggattt gactgtccca atcgtgatgg aactgtggct
    10681 catggaggct gtactttttg tacggtttca ggttctggag atgctattgt agccccagat
    10741 gcgcctatcc gtgagcaatt ttataaggaa attgacttta tgcaccgtaa gtggccggat
    10801 gttcagaagt atctggttta ttttcaaaat tttaccaaca ctcatgaaaa ggtggaagtt
    10861 attcgagagc gttatgaaca ggctatcaat gagccaggtg tggtaggaat caatattgga
    10921 acgcgcccag actgtttacc agacgaaacc atcgaatatt tggctgagtt atcggagtgc
    10981 atgcatgtga cgtttgaatt gggcttgcaa actacttatg aagcaacctc tgacctgatt
    11041 aaccgtgcgc attcttatga attgtaggtg gaaacggtca agcgtttgag aaagtatcca
    11101 aaaattgaga ttgtttccca tttgatcaat ggtttgcctg gtgaaaccca tgagatgatg
    11161 gttgaaaatg tccgccgttg tgtcacggat aacgatattc aagggattaa actgcatttg
    11221 ctccatctta tgacaaatac tcgtatgcaa cgagattacc atgaggggcg tttacaattg
    11281 atgagtcagg acgaatatgt cagggtcatc tgtgaccaac tggaaattat tcccaaacat
    11341 atcgtcatcc atcgaattac aggagatgcg cctagggata tgctgcttgg gcctatgtgg
    11401 agcctcaata aatgggaagc tctcaacagc attgagatgg agatgcgacg tcgtggaagt
    11461 gttcaaggat gcaaggctgt aaaacaggag tttgaaaatg aaaagaccac ttgagatggc
    11521 acatgatttt ttggctgagg tcgtgacaaa agaggatgtc gtagtggatg cgactatggg
    11581 aaatggtcat gacacgcttt ttttagccaa gctagccaag caagtctatg cctttgatat
    11641 tcagaagcaa gccttggaaa agacccaaga gcgtttgcat caggctgact tgacaaatgc
    11701 ccagttaatc ttgcaaggcc atgagacact ggaccagttt gtgataaaag ctaaggcagg
    11761 gatttttaat ctgggctatt tgccgtcagc tgataagtct gtcatcaccc gaccgcagac
    11821 aacgattgag gcattagaaa agctatgtgg cttacttgtc aaaggtggac gaattgctat
    11881 tatgatttac tatggtcatg aaggaggcga tctcgagaga gatgctgtct tggattttgt
    11941 gatccagttg aaccaacaag agtacacagc tgccatttac cgaactttaa accaagtcaa
    12001 caacccgccg tttttagtga tgattgaaaa attagagaga tacagacatg gataaacaat
    12061 acttacacga aaagctggat gccatgcgcc agaattttgt tgaatcaacc caccacgaac
    12121 gagcggtggg cgtgctagac caagcgcata tgagcaaaaa aatgcttaaa atcaagaaaa
    12181 aattagttgc tcttgaaatg gaacggtgcc agagaaaaat tgagcacaaa gactgttcca
    12241 agattgacca aaaaatcaaa gagcagaagg agatatttga atcctgttgt aaaaaagatt
    12301 aaggaggacg tgcgtggaat tactgattta cctcatccta tttttactgg ttttgattgt
    12361 ctcaagtaca accaataagc tcctgccctt tttgcctctc cctttggtgc aaattctttt
    12421 gggaattgtg attggtctct ttttacccaa tactgacttt caccttaata cggagttgtt
    12481 tttggcactg gttatcggac ccttgctttt ccgagaggct gaagaagcag atgttacggc
    12541 tattttaaaa cactggcgaa tcattgttta tctcatattt ccagtgattt ttatctcgac
    12601 cctgagtttg ggtggcttgg cccatcttct ttggttcagc cttcccttgg cagcttgctt
    12661 ggctgttggg gcagcccttg gtcctacgga cttggtggcc tttgcctctc tttcggagcg
    12721 ttttagcttt cctaagcgcg tgtccaatat tcttaagggc gaaggactct tgaatgatgc
    12781 ttctggtttg gtggcttttc aggtagcttt gacagcttgg acaactggag ctttttctct
    12841 ggggcaagct agcagttcgc tcatcttttc aatcctaggc ggttttttaa ttggattttt
    12901 aacagccatg accaaccgct tcctccatac cttcttgcta agtgtgcgcg caacggatat
    12961 tgccagtgaa cttttattag aattgagttt gcctctagtg accttctttc tggcagaaga
    13021 agtccatgtt tcaggtatta ttgccgtcgt agttgctgga attttaaagg caagtcgctt
    13081 caagaaaatc acgctcctcg aagcccaagt ggatacggtg accgagacgg tctggcatac
    13141 agtgaccttt atgctcaacg gttctgtctt tgtgatttta gggatggagt tggaaatgat
    13201 agcagaacct atcttgacca atccaatcta taatcctcta cttttattgc tatctctcat
    13261 cgcccttacc tttgtcctct ttgtcattcg ttttattatg atctatggct attatgccta
    13321 tagaacccga cgcctcaaga aaaagctaaa taagtatatg aaggacatgt ttctcttgac
    13381 cttttcaggt gttaagggaa cggtgtcgat tgctacgatt ctcttgatac caagtaatct
    13441 agaacaggag tatcctcttt tgcttttcct tgttgcaggt gtgacgcttg tcagcttttt
    13501 aacaggtctc ttggtcttgc ctcatctttc tgatgaagag gaaaaaagca aggattatct
    13561 catgcatatc gccattttga atgaagtaac gctagagttg gaaaaagagt tggaagacac
    13621 cagaaataaa cttcccctct atgcggctat tgacaattat catggacgta ttgaaaatct
    13681 cattttaagc caagaaaacc aggatgatca agaagactgg gctgctttga aactcttgat
    13741 tcttagtatt gaaagtgatg gtttggaaca ggcctatgaa gaggggaaca ttagcaatcg
    13801 tgcttaccga gtttaccaac gttatctgaa aaatatagaa caaggaatca atcgtaaact
    13861 tgcctcaaga ctgacctatt atttccttgt ttccttgagg attttacgtt ttctccttca
    13921 tgaagttttt actcttggaa agaccttccg tagctggaag gacaaggagc aaagccgtct
    13981 ccgtgctctt gattatgacc aaattgcaga gctctatctt gccaatacgg agatgattat
    14041 tgaaagtttg gaaaacctga agggagtcta cagacgctct ttgattagtt ttatgcagga
    14101 gtctcgtctt cgagaaacag ctattatcag cagtggtgcc tttgtcgaac gggttatcaa
    14161 tcgtgtcaaa cccaacaata tcgatgaaat gctgagaggc tattatctgg agcgcaagtt
    14221 gattttcgaa tacgaagaaa aacgattaat tacaactaag tatgccaaga aattacgaca
    14281 aaatgtaaat aacttagaga actattcctt gaaggaagct gccaataccc tgccgtatga
    14341 tatggtggaa ttggtaagaa gaaattagtt aatactcttc gaaaatctct tcaaaccacg
    14401 tcagcgtcgc cttggattat atatgtgact gacttcgtca gtttcatcta caacctcaaa
    14461 gcagggcttt gagcaacctg cggctagctt cctagtttgc tctttgattt tcattgagta
    14521 taagattata aatgaaggag tatgacatga aaaagtggtg gaaagagctg atagacaagc
    14581 ctttattaaa agcttttttg cattattatc aagcatcaga tagtgagttg accagtgtcg
    14641 cagtagccta ctattggttg atttcgattt tccccctgct tttggtggtg gtcaatatcc
    14701 tcccctattt tcagattcct gtgggagaat ttctgtgctt tatgaaagac gttctgcccc
    14761 caagcctcta tgaaggtgtg gaaaaaatag ccagagaagt tttgacgcaa ccttcaacag
    14821 gtttattaag tttttctgtt ttatcggcgt tatggagttt ttcaaaatct atgaatttct
    14881 tgcaaaaagc ttttaacaag gcttatggcg tcgaaaagag tcgtggactt atttcccatc
    14941 agatgctaag tctcctagtc agttttggct tgcagctcct ctttgcgttt gccttgtttt
    15001 tgatcttatt tggtcagatg attttggctt tacttgctca ttattggaca aaagatggca
    15061 ttatctatca ggctttacaa gggttggcag gtcctctgat ttacgccctc ctctttgcta
    15121 tcttggtcat gctttattat tttcttccca atatatctaa caggaaaatt agctataccc
    15181 taccaggcag tgcctttgtt ctcttagtga ttttaggttt actaactctg ttctctagtt
    15241 atctcaatta ctatgtccat catttggtgg atgtccgaat tttaggttcc gttcttcttg
    15301 ttgttatgat gttttggttt atcttgattg ctaaaattgt tatcctaggc gcggttatca
    15361 atgccagtat gcagagtttg aaagatccgg tctttaaaaa agactaacta tttatccatt
    15421 ataaaagcgc atagtatcaa gactttatag aaccttgata ctatgcgctt ttgcgctttt
    15481 gtgctttgac agttttttgt atagtttttg tccaagattt ctaaatcatc tgattaaatt
    15541 cctattttcc cctatcattg tccctgtttt ttcgaaaatg gaaggagtat aataaatcta
    15601 tcaataaaat gataggagga actttatggg tcatattttc ttttttctaa gtgtcttttt
    15661 ggcagggatt ctatccttct tttctccttg tatcttacct ttgttaccgg tctatacagg
    15721 agtgttacta gatgataagg atggtgctca ggcttctagc ggcaaatttt caatctcagt
    15781 tactagttta ttacgaactc tggcctttat agcaggaatt tcctttatat ttattttgtt
    15841 gggctatgga gctggttttt taggcgattt gctttatgct tcttggttcc aatatcttac
    15901 tggggcaatt attatccttc ttggtttgca ccaaatggag attctacact ttaaggggct
    15961 ttataaggaa aagaggctac aactgcaagg acaggggcaa aatggtaagg gctatagtca
    16021 ggcattttta ttgggcttga cctttagttt tgcttggacg ccttgcgtgg ggccggttct
    16081 ggggtctgtt ttggccttgg cggcttcagg tggttcagga gcttggcagg gagctggtct
    16141 catgttggtg tatacgctgg gcttggcgct accattcttg cttctagctc tgacctctag
    16201 ttatgttttg aaacatttcc gaaaacttca tccctatctc ggaatcctca aaaaagtggg
    16261 tggttttctc attattgtga tgggactctt ggttctgttt ggaaatgctt caattttaag
    16321 tcaattattt gaataaaatg gaaaggaata tcaatatgaa aaaatggcaa acatgtgttc
    16381 ttggagcagg ttcgctcctt tggttgacgg cttgttcagg caagtccgtg actagtgaac
    16441 accaaacgaa agatgaaatg aagacggagc agacagctag taaaacaagc gcagctaaag
    16501 ggaaagaggt ggctgatttt gaattgatgg gagtagatgg caagacctac cgtttatctg
    16561 attacaaggg caagaaagtc tatctcaaat tctgggcttc ttggtgttcc atctgtctgg
    16621 ctagtcttcc agatacggat gagattgcta aagaagctgg tgatgactat gtggtcttga
    16681 cagtagtgtc accaggacat aagggagagc aatctgaagc ggactttaag aattggtata
    16741 agggattgga ttataaaaat ctcccagtcc tagttgaccc atcaggcaaa cttttggaaa
    16801 cttatggtgt ccgttcttac ccaacccaag cctttataga caaagaaggc aagctggtca
    16861 aaacacatcc aggcttcatg gaaaaagatg caattttgca aactttgaag gaattagcct
    16921 aggaggtgtc ttatgaatga taagttaaaa atcttcttgt tgctaggagt attttttcta
    16981 gccataaccg gtttctatgt tctattgata cgaaatgcag ggcagacaga tgcctcgcaa
    17041 attgaaaagg cggcagttag ccaaggagga aaagcagtga aaaaaacaga aattagtaaa
    17101 gacgcagact tgcacgaaat ttatctagct ggaggttgtt tctggggagt ggaggaatat
    17161 ttctcacgcg ttcccggggt gacggatgcc gtttcaggct atgcaaatgg tagaggagaa
    17221 acaaccaagt acgaattgat taaccaaaca ggtcatgcag aaaccgtcca tgtcacctat
    17281 gatgccaagc aaatttctct caaggaaatc ctgcttcact atttccgcat tatcaatcca
    17341 accagcaaaa ataaacaagg aaatgatgtg gggacccagt accgtactgg tgtttattac
    17401 acagatgaca aggatttgga agtgattaac caagtctttg atgaggtggc taagaaatac
    17461 gatcaacctc tagcagttga aaaggaaaac ttgaagaatt ttgtggtggc tgaggattac
    17521 catcaagact atctcaagaa aaatccaaat ggctactgcc atatcaatgt taatcaggcg
    17581 gcctatcctg tcattgatgc cagcaaatat ccaaaaccaa gtgatgagga attgaaaaag
    17641 accctgtcac ctgaggagta tgcagttacc caggaaaatc aaacagaacg agctttctca
    17701 aaccgttact gggataaatt tgaatccggt atctatgtgg atatagcaac tggggaacct
    17761 ctcttttcat caaaagacaa atttgagtct ggttgtggct ggcctagttt tacccaaccc
    17821 atcagtccag atgttgtcac ctacaaggaa gataagtcct acaatatgac gcgtatggaa
    17881 gtgcggagcc gagtaggaga ttctcacctt gggcatgtct ttacggatgg tccacaggac
    17941 aagggcggct tacgttactg tatcaatagc ctctctatcc gctttattcc caaagaccaa
    18001 atggaagaaa aaggctacgc ttatttacta gattatgttg attaatactc ttcgaaaatc
    18061 tcttcaaacc acgtcagcgt cgccttaccg tatgtagggt t
//
LOCUS       DAVBOD010000044        16946 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 640-05
            SAMEA1012484-rid20186543.denovo.044, whole genome shotgun sequence.
ACCESSION   DAVBOD010000044 DAVBOD010000000
VERSION     DAVBOD010000044.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012484
            Sequence Read Archive: ERR059358
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 16946)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16946)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979948.1
            Genome Coverage       :: 595x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:03:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,266
            CDSs (total)                      :: 2,219
            Genes (coding)                    :: 2,091
            CDSs (with protein)               :: 2,091
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 71 of 128
            Pseudo Genes (incomplete)         :: 50 of 128
            Pseudo Genes (internal stop)      :: 33 of 128
            Pseudo Genes (multiple problems)  :: 22 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16946
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012484-rid20186543.denovo.044"
                     /strain="NIG 640-05"
                     /db_xref="taxon:1313"
     gene            102..527
                     /locus_tag="VQ862_001546"
     CDS             102..527
                     /locus_tag="VQ862_001546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000772904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1642 domain-containing protein"
                     /protein_id="HET3115865.1"
                     /translation="MKLNELIKKYKKLEGVWNAEGAELVRQIFLQDLEQLDKPQPVKV
                     PQCVAEYIEFKKKNNFHVYGLAWLNGYEVEKEKRYFVKIKGNIKENMLVYGELLKRYF
                     FTKSFSLDDVIYSHTRKELEAANFGWVFDCPGIEIEEVE"
     gene            527..1041
                     /locus_tag="VQ862_001547"
                     /pseudo
     CDS             527..1041
                     /locus_tag="VQ862_001547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000502465.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
     gene            1038..1427
                     /locus_tag="VQ862_001548"
     CDS             1038..1427
                     /locus_tag="VQ862_001548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000612387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3115866.1"
                     /translation="MIPKFRVWHHELGRLMSVKCMFFQDSEIEEFELNDALMNDYITA
                     YPDEIELMQSTGLKDKNGKEVFIGDIVKCTRGCLHEVYLEKEYGGTFIGGMPAVYLKG
                     LGDGYAWTEYEEIIGNIYENPELLEDK"
     gene            1427..1663
                     /locus_tag="VQ862_001549"
     CDS             1427..1663
                     /locus_tag="VQ862_001549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001067623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3310 domain-containing protein"
                     /protein_id="HET3115867.1"
                     /translation="MNPEIIDNINKPSHYQGANGLEAIDVVHNFVGSLSGASAFFWGN
                     AIKYMLRFQKKNGLEDLKKARKNLDWLIEEMEHE"
     gene            1660..1818
                     /locus_tag="VQ862_001550"
     CDS             1660..1818
                     /locus_tag="VQ862_001550"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3115868.1"
                     /translation="MNTHCMKATPLLPWGRLRKSAKKQELLNGASISEFAIEDICTFF
                     GIEIQERK"
     gene            2030..2431
                     /locus_tag="VQ862_001551"
     CDS             2030..2431
                     /locus_tag="VQ862_001551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000736386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HET3115869.1"
                     /translation="MKKLSDEELKTLDRELFKFQNIQRTIDLRRLELETRNPDAQSGP
                     TVGISKPTETIAIRIADDPTLKFLEGFKGIINKLLSNLVEEDKEIFNLRWRYPQLRWE
                     EIAEQKFMSKATIYRRRRIILEQYAIMKGEL"
     gene            2620..3162
                     /locus_tag="VQ862_001552"
     CDS             2620..3162
                     /locus_tag="VQ862_001552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000397549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HET3115870.1"
                     /translation="MEFVSPIKDNDNIQAMKDYLREWNEMYYMLFITGLNTGLRVGDI
                     LTLKVKDVQGWHIKLRERKTGKQITRRMTKELKKEMRRYVEGKPFHHFLFKSRQGQNK
                     AITRERAYQIIHEAAEELGIDNVGTHTMRKTFGYKYYNKTKDVGTLQKMFNHSSPAIT
                     LRYIGIEQAELDDALRNFVI"
     gene            3326..3517
                     /locus_tag="VQ862_001553"
     CDS             3326..3517
                     /locus_tag="VQ862_001553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000238198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3115871.1"
                     /translation="MVKEYRDDFLGEKAFEKLNKDIDANPEVGFEIVGYTQTAFVNGM
                     HIPLTAILVKWNNFFKESE"
     gene            3637..3957
                     /locus_tag="VQ862_001554"
     CDS             3637..3957
                     /locus_tag="VQ862_001554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000282427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HET3115872.1"
                     /translation="MYNKPIRPSLKSKKWEKFRDRIMRKHDYLCQESLRYGISVQAEM
                     VHHIFPVSEYPELEFVEWNCLPLTNKKHNTFHDRVNDRVINQGLYWQKKRKKEFLNFF
                     KNEK"
     gene            4095..4487
                     /locus_tag="VQ862_001555"
     CDS             4095..4487
                     /locus_tag="VQ862_001555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001118284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="P27 family phage terminase small subunit"
                     /protein_id="HET3115873.1"
                     /translation="MAKPITAKSIKSKVVKQMKDLGTYRKEFEMIIDIFAGMLYQYQK
                     LAQDYADMGYPVTDTYVNKAGAENERKVPILTAMEILRKDILSYSNQLMMNPKSLGEV
                     VEQEGESVLTEVLKFKNEIKKKRVTGNG"
     gene            4480..6210
                     /locus_tag="VQ862_001556"
     CDS             4480..6210
                     /locus_tag="VQ862_001556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001845577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase large subunit"
                     /protein_id="HET3115874.1"
                     /translation="MGNLDKAKKYAQHVLTHREEHCEENILAAERFFRDLENPTFEMD
                     EDMVDFVIHFIENVIVHQQGDDMFAVSIRNKPLLLQPWQHFVVVNLFGFYYKGTNERR
                     FKEALIMLARKNGKTSFTAAIALAYQILDTDSGSKCYIVANSVKQAMEAFGFLRFNVE
                     RWNDKNIRIKDNNQEHSITANFGDEGSFFIQALANDESRLDSLNGNVIILDEAHTMRN
                     SKKHGLMKKTMSAYRNSMLFVISTAGDIPTGFLANRLKYCQKVLKQLVTDDSFFIFIC
                     KANQSADGDVVNYLDENILKMANPSWGVTVSLKALKEEAEQAMNDPQTRNEFFNKTLN
                     IFTNSMNAYFNPDEFIASDSCYDWSLEELARLPIRWYGGADLSRLHDLTAAALYGVYH
                     DGEKDVDICITHAFFPRINAQKKANDDGIPLFGWQSDGWLTMSNTPTVLYDDIVKWFI
                     KMREKGFKIAAVGMDRKFGREFLTKMKQARFKMIDQPQLFYLKSEGFRRIEFKVKNKE
                     FYYLHSDAYEYCVSNVRAIEKVDDAVQYEKLDGDGGTARIDLFDASVFACIQALANLG
                     KGGDVMRFFD"
     gene            6218..6436
                     /locus_tag="VQ862_001557"
     CDS             6218..6436
                     /locus_tag="VQ862_001557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001002923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3115875.1"
                     /translation="MNEIVLSEHEINLLINKGRVKVILNGEVVTIRQRHMKNLMAETV
                     KWEKQVIDVSQNIVRNKHFDSLFQNTFR"
     gene            6454..7656
                     /locus_tag="VQ862_001558"
     CDS             6454..7656
                     /locus_tag="VQ862_001558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000510804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HET3115876.1"
                     /translation="MGIFEKFWKRNKPSKSINMLSHSDLGLSNLMDSYVPLARNPDVV
                     TAVNKIADLVSNMTIHLMENTDKGDIRIRDGLARKIDINPCKHMTRKSWIFKIVRDLL
                     LYGDGNSVLHVEYEPVTDYISNLRPFPMREVSFQTDKDSYVISFRGEEYSPDEVVHFV
                     INPDPDIPYIGTGFRVTLTDVVQSLNMATKTKKSFMNGKNIPSLIVKVDSSSAELDSE
                     QGRERIAEKYLSTSRVGAPWIVPEALLDIQQVKPLSLTDIALNESVELDKRTVAGLLG
                     VPAFILGVGEFNKTEYNNFVNTTVMSIATTITQTLTRDLLLSSNRYFKLNPRSLFSYN
                     ITELSAVAQQMANSAAMRRNEWRDWLGMAPDPEMEELIVLENFLPQEKLGDQNKLKGG
                     EEENAKAK"
     gene            7640..8215
                     /locus_tag="VQ862_001559"
     CDS             7640..8215
                     /locus_tag="VQ862_001559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001172113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 family phage prohead protease"
                     /protein_id="HET3115877.1"
                     /translation="MQKRNSYRATQFQTREEESGDLILSGYFIKFDEETELWPGYCEV
                     IKRAGVEKAVTDADIRALFNHDDSLVLGRTGNGTLTLGVDDVGLFGDIIINKDDPQAV
                     GAYARVKRGDVIGCSFGFIPVKIETEEREDGSYLDTVLELEIFEVSPCTFPAYPQTEI
                     AARQKDFESQKRANREALDKRKKEIKEKFNL"
     gene            8212..9384
                     /locus_tag="VQ862_001560"
     CDS             8212..9384
                     /locus_tag="VQ862_001560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001037661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage major capsid protein"
                     /protein_id="HET3115878.1"
                     /translation="MNKLLILGARMRNKADKVVELEESIKELNKRSELEAKKLEQAGT
                     DEEVSAVEKNLEDIQKESDEKEAEKEQLEKEIEDLKNQVEELNRKAPTYPSQEKRGGQ
                     KLERRDAIAKYIRTGQTRDIVGLKTTDSGSAALIPTEVLKPHFVNKTRNPLLDLVERV
                     KVNSGSGKYPVIKKTDGVMVSIDELKSNPELGKPAISEIDYSIKTYRGYVPVSQEMID
                     DADYDIMSIVEDEVFNQGDNTELSLVTAVLKTATQADAAGFDGIKDIYNKKLKSIYKA
                     SIVVTKSMFAALDKVKDKDGRYMLQTDVASPTGYSFGGKTIYKVDDTVFGNEGDMKFF
                     IGDVTEFVKEFDRSQVSVKWVNNDIYGQLLGLFIRLDIKKADEEAGFFGTYTDVVA"
     gene            9396..9686
                     /locus_tag="VQ862_001561"
     CDS             9396..9686
                     /locus_tag="VQ862_001561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3115879.1"
                     /translation="MSYKVIRPFKDLADPENHDYAVGDIFPREGYEPTDSFTNGLLTG
                     ANTAGSIFLEVLGDDEPKKPAPETKEVKEEPAVEQEETVEETAEESAEEVEE"
     gene            9689..9970
                     /locus_tag="VQ862_001562"
     CDS             9689..9970
                     /locus_tag="VQ862_001562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000371962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head-tail connector protein"
                     /protein_id="HET3115880.1"
                     /translation="MDQGQLLELLKLKLGISTDLRDKPLKKIISSVITELTDNLGIEL
                     VGERADHEMFIVDYAAYRYEGGVDMPRHLQWRLHNLQIASKKEVKNVES"
     gene            9957..10256
                     /locus_tag="VQ862_001563"
     CDS             9957..10256
                     /locus_tag="VQ862_001563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000267058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head closure protein"
                     /protein_id="HET3115881.1"
                     /translation="MWNHEITLISKKVTGKDKLLQPISEDVEVTLLCRKKRVTRSEFY
                     QANQVGLKPSLVVEIRNFEYENQELAKFEGKQYHILKTYPIDSEILELTLSEVLK"
     gene            10253..10600
                     /locus_tag="VQ862_001564"
     CDS             10253..10600
                     /locus_tag="VQ862_001564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000063887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 gp10 family phage protein"
                     /protein_id="HET3115882.1"
                     /translation="MSNDLADLIAKELAAYSDEVTEEVDKIAEQVTDETVDELKETSP
                     KRYGKYRRSWKKKKLANGSFVVFNAVASLTHILENGHLSRNGGRVAGIVHIKPAEEKA
                     IQNFEKRIKEIGK"
     gene            10597..10920
                     /locus_tag="VQ862_001565"
     CDS             10597..10920
                     /locus_tag="VQ862_001565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3115883.1"
                     /translation="MKLSDFAAILEQANLPVTYRAFKIGNAPDLPYLVYYESSPVINS
                     ADNTVNHQIKSVTVELAFESKDEDLEERLEELWANHKLFFEVQEETFIETERLYVKSY
                     TVYLY"
     gene            10932..11510
                     /locus_tag="VQ862_001566"
     CDS             10932..11510
                     /locus_tag="VQ862_001566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000191275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HET3115884.1"
                     /translation="MTQENKVTFGLENVHIAPIKTLAADGVITYGDVFRFPGAIELIL
                     DTKGETTPIKADNKDYHFMNSNEGYEGKLKIPHIIDEFATKILGEIKDPQTGVMTEKA
                     DASLTEFAMMFQFEGDKNKTRYVMYYCFASRPSLGSKTKNGTSTNERELSFKASPRPL
                     DTVVKRSITSADDKDAYDNWFKKVYEPTAVAA"
     gene            11522..11941
                     /locus_tag="VQ862_001567"
     CDS             11522..11941
                     /locus_tag="VQ862_001567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003047255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3115885.1"
                     /translation="MRKIVLVGDQEYELGTNGYTPIAYKQQFGKDYFQDLFSMLKNQS
                     FMNELNKLETDKELTATNIDISMLSDFDMTFFNRLFWTFAKSANPHIKPYEQFFMEME
                     IFPIQEVGPVLMEMLNASMTTKKHQMSQNQLAKKSSQ"
     gene            12219..14978
                     /locus_tag="VQ862_001568"
     CDS             12219..14978
                     /locus_tag="VQ862_001568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000918321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tape measure protein"
                     /protein_id="HET3115886.1"
                     /translation="MAGNIKGIKIEIDGDTQPLQKALKNVNKAATDASQELRQIDKAL
                     KFDTGNVTLLTQKQEVLQKQVSTTKEKLETLRQAQSQVEQQFKNGDIGADQYRAFQRE
                     VEVTQNVLKGYEGKLANVNQALNENGSATQNNKNQLKELQNEQSQLASEMSKVTSSFK
                     LQESALGSNASEAERNALAQKKIGAQSEIVSKQISNLEQQLEITKKEFGENSTQANKM
                     ESELNQAKTAFNHLNDEMKGTKSAADSTQESLSEISRNLRAELLQQFSEKLSAISEKL
                     VEVGKEALEAAAQMQASNAQFTTVFGDMETQAREALNAIGQEMDIVPERLQGSFTQMA
                     SFAKTSGLDTAQALDLTSRATRAAADGAAFYDKSIESVSESLQSFLKGNFANDAALGI
                     SATETTRNAAANKLYGKSFKDLSEAQKQLTLLQMVEDGNKLSGALGQAARESDGLENV
                     MGNLKQAGTNALSAIGQPLLEMMIPVFQTLATIVKGVAELFNSLPDPVKDFVVILGTV
                     VTAVGVIAPIFLTLQALAEFLKISIGEMIIAALPIIGTAIAIAAAVAAIIVIVKYLWE
                     TNEGFRDAVTTVWNAILAVINTVVSEISDFIMSIFGTVVTWWTENQELIRTSAETVWN
                     AIYTVISTILDILGPLLQAGWDNIQLIITTTWEIIKIVVETAINVVLGVIQAVMQIIT
                     GDWSGAWETIKGVFSTVWQAIQSIVQTIFSAIQSYISNILNGISGTVSNIWNSIKDTV
                     SNVLNAISSTVSSVWEGIKSTISSAINGARDAVSSAIEAIKGLFNFNISWPHIPLPHF
                     YVSGSANPLDWLSQGVPSIGIEWYAKGGIMTKPTIFGMNGNNIMVGGEAGNEAVLPLN
                     DKTLGAIGRGIAQTMGGTSPTINITITGNTVREEADISRIADEVAQRIADELQRRRQL
                     RGGFA"
     gene            14975..15697
                     /locus_tag="VQ862_001569"
     CDS             14975..15697
                     /locus_tag="VQ862_001569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HET3115887.1"
                     /translation="MIKHNELVIDGVRTSSFPFKIIVHDSPSIALGESKTALLEHGGV
                     SGAIVQTNKHRELVKKTYTIYLVKPTEEQMNQFMSLFIREKFWLESERVKTTRLWCYK
                     VNVSDLEEVQPGLYMTKATFTCHPTKYFKDSDTQRLTRSGTLTVQGSALAFPKITIVG
                     QSASETSFTIAGQVIRLERLTESLVMVNNPDNPSFKTTTGKPVKWSGDFITVDPAKVK
                     NIGVVLGPGIQSIEIETVWGWA"
     gene            15698..>16946
                     /locus_tag="VQ862_001570"
     CDS             15698..>16946
                     /locus_tag="VQ862_001570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002644521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HET3115888.1"
                     /translation="MLYLLNKDVRTVRWNGEPLHEATSAIVKETMNGDFTLTVKYPIS
                     DSGIYQLIQEDMLIKAPTPVLGAQLFRIKKPVEHNDHLEITAYHISDDVMQRSITQMS
                     VTSQSCGMALARMVQNTKTALGDFSFNSDIQDRRTFNTTETETLYSVLLDGKHSIAGT
                     WEGELVRDNFAMTVKKSRGENRGVVITTHKNLKDYQRTKNSQNVVTRIHARSTFKPEG
                     AEKETTIRVTVDSPLINSYPYINEKEYENNNAKSVEELQKWAQSKFSNEGIDKVSDAI
                     KIEAYELDGQVVHMGDTVNLKSWKHNVDAFKKAIAYEFDALKEEYISLTFDDKAGIGG
                     SRSSGGLSSAADAILGVTESAQEIALEKALQNADLDFDHKAGLLRQEISDDIELAKAR
                     AEEVKRELSDTINQRFNSFDNGPL"
BASE COUNT         5527 a         2912 c         3920 g         4587 t
ORIGIN      
        1 ttggttgcca aaatctaagg agtttgatga ttgggttggc tattcgccaa gcatgtctca
       61 gttagttatt gcagtttatt tgatttacag aggaagcgaa gatgaaactt aatgaattga
      121 ttaagaaata taaaaaactt gagggtgtat ggaatgctga aggagcagaa ctagttcgtc
      181 aaatttttct gcaagacttg gaacaactag ataaaccgca accagtcaaa gttccgcagt
      241 gtgtggcgga atatatagaa tttaaaaaga aaaacaattt tcatgtttac ggtcttgctt
      301 ggcttaacgg ctacgaggtc gaaaaagaga agcggtattt tgttaagatt aaagggaata
      361 ttaaagaaaa tatgttggtt tatggagaac ttttgaaaag gtatttcttt acaaaaagct
      421 ttagtttaga cgatgttata tattcccaca ctcgtaaaga actagaagcc gcaaacttcg
      481 gctgggtgtt tgattgccca ggtattgaga ttgaggaggt ggaataatgg gagatatacg
      541 aatactagac gcttgttgtg gcagtcgtat gttttggttt gataaaaatg agagtcatac
      601 aactttcatg gacatcagac aagaaaaatt tgaaatacat ggaaaaaggt aaacgtaaac
      661 cctgacgttg tcggagattt tcgtgatatg ccattcgatg gtgaaacatt taatctagta
      721 gtatttgatc cgccacattt gaaatgggca ggtcaaaact caattatgcg atcacaatat
      781 ggccagctgg ataaagttac ctggtcggaa gatttagcca agggttttga agaatgtatg
      841 agagttctaa aagttggagg tactctagtt tttaaatggt ctgattgtca aatcaacgtt
      901 aaagaagttc ttaaatctgt accttttaaa ccattgtttg gacaacaaag aggtactacg
      961 cattggatga cgtttatgaa atttgagaag gtcacagaga gaaaggacgg cacgtttgta
     1021 aaagaggagg atttggcatg ataccgaaat ttagagtgtg gcatcatgaa ttaggtagac
     1081 tgatgtcagt caaatgtatg ttttttcagg atagcgagat tgaagaattt gagttaaacg
     1141 atgctttaat gaatgattac attacagctt atcctgatga aatcgaactc atgcaatcaa
     1201 caggactcaa agacaagaac ggcaaggagg tattcatcgg tgacatcgtt aaatgtacaa
     1261 gaggatgtct ccatgaagta tatttagaaa aagaatacgg tggtacattc ataggtggaa
     1321 tgcctgctgt atacctaaaa ggacttggag atggatatgc gtggacggaa tatgaggaaa
     1381 tcatcggcaa catctacgaa aatccagagc ttttggagga taaataatga acccagaaat
     1441 aattgacaat ataaacaaac caagccacta ccaaggtgca aacggtcttg aggctatcga
     1501 tgttgtgcat aacttcgttg ggagcctttc cggagcgtct gctttctttt ggggcaacgc
     1561 aatcaagtat atgttacggt ttcaaaagaa aaatggtctg gaagacctga agaaagctag
     1621 aaagaatctt gactggctga ttgaggagat ggagcatgag tgaatacgca ttgtatgaag
     1681 gcgacacctt tattaccatg gggacgcttg cggaaatcag caaagaaaca ggaattgctg
     1741 aacggtgcaa gtatttcaga gtttgccatc gaagatatct gtacgttttt tgggattgag
     1801 atccaagaaa ggaaataaaa gtcaatgaac aaaagaatta agaagaagat agctaaacgg
     1861 cagatacaag aaaagcaaga agaattatac aaacaactac ggaaattaag ttctgaagaa
     1921 attgaagcta taactaaaat gattaatcag gcagtttcta atattcgcaa ggctttctct
     1981 cagatatttg ataacttgtt tacatttttg aaaaacttgg aggtggaaat tgaaaaaatt
     2041 gagcgacgaa gaactcaaaa cgttagacag agaacttttc aaatttcaaa acattcaacg
     2101 cacaatagac ttaagaaggc tagaattaga aaccagaaac ccagatgctc aaagtgggcc
     2161 aactgtagga ataagcaaac ctaccgaaac tatcgcaatc agaatcgcag atgatccgac
     2221 tttaaaattt cttgaaggat ttaaagggat tattaacaaa ctcttaagca atctagtcga
     2281 ggaggacaaa gaaattttca atctacgctg gagataccct caactgagat gggaagaaat
     2341 agcagaacag aaattcatga gcaaagctac aatctatcga cgtagaagga ttatcttaga
     2401 acagtacgct ataatgaaag gtgagttgta aataagattg agacaaaaga catcttgaag
     2461 tctcacaaaa aaagggctat tatgatagca tgaacttctg aaaacaaaaa cacaaatcac
     2521 atgttggagt tatcctattt ttacagaaaa gttgtttaac agaggaacat catgagtcag
     2581 caaccagctg gctttttgtt ttgtagaaag gaggcagtta tggaatttgt atcaccgata
     2641 aaagacaatg ataatattca agctatgaaa gattatctca gagaatggaa tgagatgtat
     2701 tatatgctat tcatcacagg cctgaatact ggcttacgag tcggagatat acttaccttg
     2761 aaagttaaag atgttcaagg ttggcacatc aaactgagag aacggaagac tggcaagcag
     2821 ataacaagac ggatgacaaa agaactcaag aaagaaatga ggagatatgt tgaaggcaaa
     2881 ccatttcatc atttcttatt caagagtagg caaggtcaga ataaagcgat cactcgtgag
     2941 cgagcctatc aaatcataca tgaagcagct gaagaacttg gcattgataa tgttggcaca
     3001 catacaatgc gcaagacatt cggctataaa tattacaaca agacaaagga cgtaggaaca
     3061 ttacagaaaa tgttcaatca ctcatcacct gcaatcaccc tgagatacat agggatagag
     3121 caagcagagc ttgatgacgc actacggaac tttgtcattt aattttttag atattacttt
     3181 cacataatga gttaagcata aactgaaaaa atgaaagtct tcaaaaccta tgattagtaa
     3241 gggtttgaga tttagagtga gtttaacaaa atataagata tgtgaaagtg agggataaaa
     3301 ttggtatagt tacaagaggt gaaaaatggt aaaagaatac cgtgatgatt ttcttggaga
     3361 aaaggccttc gagaaattaa ataaagatat tgatgccaat cctgaagttg gctttgaaat
     3421 tgttggatat actcaaacag catttgtaaa tggaatgcat ataccgttaa cagccatact
     3481 agtaaaatgg aataattttt ttaaagaatc agaatgagac aaaagacatc ttgaagtctc
     3541 acaaaaaaag gtttattatg gtagcataga tttcttgtat gaggagggga taggtcaaag
     3601 gcctatccct tttagcattg agaaaggagg tttgagatgt ataacaaacc tatcagacca
     3661 tccttgaaat ctaagaagtg ggagaagttc cgtgatagga taatgcgtaa gcatgattat
     3721 ctttgccaag aaagtttgcg ttacggaatt tctgttcaag cagaaatggt acatcatatc
     3781 tttcctgtgt ctgaatatcc tgagcttgaa tttgttgaat ggaattgctt gccattgacg
     3841 aataagaaac ataatacgtt tcatgataga gtgaacgata gagtaatcaa ccaaggattg
     3901 tattggcaga aaaaaagaaa aaaagaattt ttaaattttt tcaaaaatga aaaatgaaaa
     3961 tttttaatcc ccccctcttt ttgaaaaatc attttggcca gtagggtact ggtgaaggga
     4021 actttttcca agtcgggggc cttcaaacaa aaagggggta aaaactaagc gattttgacg
     4081 aaaggaggta gtttttggct aaaccaatta cagcaaagtc gattaagtca aaagtggtca
     4141 agcagatgaa agacttggga acttatcgta aagagttcga aatgatcatt gacatttttg
     4201 caggtatgtt ataccagtat cagaaacttg ctcaagatta tgctgatatg ggttatccag
     4261 taacagacac ctacgtcaat aaggctggtg ctgaaaatga gcgcaaagtt ccaatcttga
     4321 cagcgatgga aattttgagg aaagatatac tcagctactc taatcagttg atgatgaatc
     4381 ctaagtcgct cggtgaggta gtagaacaag agggtgagtc agttcttact gaggtactga
     4441 agttcaagaa cgaaatcaag aagaagcgag tgactggcaa tgggtaatct tgataaagct
     4501 aaaaaatacg ctcaacacgt cttaactcac cgagaagaac attgcgaaga aaacatcctt
     4561 gctgctgaac gttttttccg tgatttagaa aatccaacct ttgagatgga tgaggatatg
     4621 gtggattttg ttattcactt tatcgagaac gtgatagttc atcagcaggg cgatgatatg
     4681 tttgcggtat ctatccgtaa caagccattg cttttgcaac cgtggcaaca tttcgttgta
     4741 gttaatctgt ttggttttta ctacaagggt acgaatgagc gcaggttcaa agaagcgctt
     4801 atcatgcttg ctcggaagaa tgggaagacc tcgtttactg ctgcaatcgc acttgcttat
     4861 cagatattag atacagatag cggttccaaa tgctatatcg ttgctaactc agtcaagcaa
     4921 gcgatggaag cttttggttt tttaagattc aacgttgaac gctggaacga taagaacatt
     4981 cgtatcaagg ataataacca agaacactct atcaccgcca attttggtga tgaaggttct
     5041 ttctttatcc aggctttagc gaatgatgag agccgtctgg actctttgaa cggaaatgtt
     5101 atcatcttgg acgaagctca cacaatgagg aacagtaaga aacatggtct tatgaaaaaa
     5161 acaatgtcag catacagaaa cagtatgctt tttgttatct caacggctgg ggatattcct
     5221 accgggttcc ttgctaaccg tctgaaatac tgtcaaaagg tgctcaagca attagtcact
     5281 gatgattcat ttttcatctt catctgcaag gctaatcaat ctgctgatgg ggacgtggtg
     5341 aactatctgg acgagaatat cctcaagatg gctaatccgt catggggtgt cacggtttcg
     5401 ctcaaggctc tcaaggaaga agcagagcag gctatgaatg atcctcagac aagaaatgag
     5461 tttttcaata agaccttgaa tatcttcact aactctatga acgcttattt taatcctgat
     5521 gagtttattg cgtcggatag ttgctacgat tggagtttag aagagctggc acgtttgcct
     5581 attcgttggt atggtggtgc ggacttgtca agattgcacg acttaacagc tgctgctctc
     5641 tatggtgtct atcatgacgg tgagaaagac gttgatatct gtatcacaca tgctttcttc
     5701 cctcggatta atgctcagaa aaaagctaat gatgacggga ttccactctt tgggtggcag
     5761 tctgacggtt ggttgacgat gagcaacact ccgaccgtcc tctatgatga tatcgtcaaa
     5821 tggttcatca agatgaggga gaaagggttc aagattgctg ctgtcggaat ggataggaag
     5881 tttggccgtg agttcttgac gaagatgaaa caagctcggt tcaagatgat tgaccaacct
     5941 cagctttttt atctgaaatc agagggattc agacggattg agtttaaagt taagaataaa
     6001 gaattttact atcttcattc tgatgcttac gaatactgtg tgagcaatgt tagagcaatt
     6061 gaaaaggtgg acgatgctgt gcaatatgag aaattagatg gagacggtgg gactgcaagg
     6121 attgacttgt ttgatgccag cgtctttgct tgtatacagg ctcttgctaa tcttggcaag
     6181 ggtggtgatg tgatgagatt ctttgattag gtgaattatg aatgaaatag tattatcaga
     6241 acatgaaatt aacttgctga tcaacaaagg gcgagttaaa gtaattttaa acggggaagt
     6301 agtaactatt cgtcaaagac atatgaaaaa tttgatggct gaaacagtaa aatgggaaaa
     6361 acaggtaatt gatgtcagtc agaatatcgt aagaaataaa cactttgatt cactttttca
     6421 aaatactttt cgttagaaag gaggtgagga aacatgggta tttttgaaaa gttttggaaa
     6481 cgaaacaagc caagtaagtc aatcaacatg ctgagtcatt cagatttagg gttgtcaaac
     6541 ctgatggact cgtatgtacc tttggccaga aatccagatg tggtgacagc ggttaataag
     6601 attgctgatt tggtctctaa tatgaccatc cacttgatgg agaatacaga taaaggtgat
     6661 atcagaatcc gtgatgggct tgctagaaag attgatatca atccgtgtaa acacatgaca
     6721 aggaagtcat ggattttcaa gattgtgcgc gatttgcttt tatatggcga tgggaactct
     6781 gtcctacatg tggaatatga acctgttacg gattatattt ctaatctaag accatttccg
     6841 atgagagagg tttcattcca aacagataag gattcctatg taatctcatt taggggtgaa
     6901 gaatattccc ctgatgaagt agtccacttc gtcatcaatc cagatccaga tattccatac
     6961 attggtactg gttttagggt gacgttgaca gatgtggttc aaagtttgaa catggctacc
     7021 aagactaaaa aaagctttat gaacgggaag aatattccta gtcttatcgt taaagtagac
     7081 tcgtctagtg ctgaactaga ttcggagcaa gggcgtgagc gtatcgctga gaagtatttg
     7141 agtactagca gggttggcgc tccatggatt gttccagagg cattgctgga cattcagcag
     7201 gtaaaaccgc ttagtctaac ggacatcgct ttaaacgagt ctgtggaatt ggataaaaga
     7261 acagttgcag gtctattagg agtacctgct tttattttgg gtgtaggaga gttcaacaag
     7321 acagagtata acaactttgt aaatacgact gtcatgagta ttgctaccac tattactcaa
     7381 acactaacca gggacttact tttgtctagc aatcgttact tcaagctaaa tcctcgttca
     7441 ctcttctctt acaacattac ggagttgtct gctgttgctc aacaaatggc aaacagtgct
     7501 gcaatgcgtc gtaatgagtg gagggattgg ctagggatgg ctcctgatcc tgagatggaa
     7561 gagttgattg ttcttgaaaa ctttctccct caggagaaac taggagatca aaataaactg
     7621 aagggaggtg aggaagagaa tgcaaaagcg aaatagctat cgtgccactc aatttcaaac
     7681 gagagaagaa gaatctggtg atttgatttt gagtggctac tttatcaagt ttgacgagga
     7741 gacggaattg tggccaggct actgtgaagt tatcaagcgt gctggtgttg agaaagctgt
     7801 cacagacgct gatatcagag ctttatttaa ccatgatgat agccttgttc tcggtcgaac
     7861 aggtaacgga actctgacac tgggtgttga tgatgttggt ctttttggag atatcatcat
     7921 taacaaggat gatcctcaag ctgttggggc ctatgcccgt gtcaagcgtg gagatgttat
     7981 agggtgtagc tttggcttta tcccggtaaa aatcgaaacg gaagaacgtg aagatggttc
     8041 atatttggac actgtcttag agctagaaat ctttgaagtg agtccatgta ctttcccagc
     8101 ctatccacaa acggaaattg ctgcacgaca aaaagacttc gaaagtcaga agcgtgctaa
     8161 tcgtgaagcg ctagacaagc gcaagaaaga aattaaggag aaatttaatc tatgaacaaa
     8221 ttattgattt tgggcgctcg tatgcgcaac aaagcagaca aagttgtaga gcttgaagaa
     8281 tcaatcaaag aattgaacaa gcgttctgaa cttgaagcta agaaattgga acaagctgga
     8341 actgacgaag aagtttcagc agttgaaaag aaccttgaag acatccaaaa agaatcggat
     8401 gaaaaggaag cagaaaaaga acaacttgaa aaagaaatcg aagatttgaa aaatcaagtt
     8461 gaagaactaa atcgtaaagc accgacttac ccaagtcaag aaaaacgtgg aggacagaaa
     8521 ttggaacgac gtgacgcaat cgctaaatac attcgtactg gtcaaactcg tgacattgta
     8581 ggcttgaaaa ctactgattc aggaagcgca gctttaatcc ctactgaagt tttgaaacct
     8641 cattttgtta ataaaacacg taatccactt ttggatcttg tggaacgtgt gaaagttaat
     8701 agtggatctg gtaaatatcc agttatcaag aaaacggatg gtgtaatggt ttcaatagat
     8761 gaattgaaat caaatccaga actcggaaaa ccagcaatca gcgagattga ttattcaatc
     8821 aagacttacc gtggatatgt ccctgtgtca caagaaatga ttgacgacgc agactatgac
     8881 atcatgtcca ttgttgaaga cgaagtgttc aatcaaggtg acaacactga attgtcatta
     8941 gttacagctg tcctcaaaac agctacccaa gcagatgcgg ctggatttga tggtattaaa
     9001 gatatctaca acaagaagct taaatcaatt tataaagcaa gcatcgttgt aactaagtca
     9061 atgtttgctg cgcttgacaa agtgaaggac aaagatgggc gctacatgct tcaaactgat
     9121 gtggcttcac ctactggcta ttcatttggt gggaaaacaa tctacaaagt agatgacaca
     9181 gtgtttggaa acgaaggaga tatgaaattc ttcatcggag atgttactga gttcgtcaaa
     9241 gagtttgacc gttctcaagt atccgttaaa tgggtgaaca atgacattta cggacaattg
     9301 cttgggcttt ttatccgttt ggatattaag aaagcagatg aagaagctgg attcttcgga
     9361 acatatactg atgttgtagc ttaaggaggt agcgtatgag ctataaagta atccgtcctt
     9421 tcaaggactt ggctgatcct gaaaatcatg actacgctgt tggcgatatc tttcctcgtg
     9481 agggatatga gccaacagat agctttacca atggcctttt gactggcgct aacactgctg
     9541 gctctatctt ccttgaggtt ttgggagatg atgaacctaa gaaaccagcg cctgaaacaa
     9601 aagaagtgaa ggaagagccc gcagttgagc aggaagaaac agttgaggaa actgctgaag
     9661 agtctgctga ggaagttgag gaatagacat ggaccaaggt cagcttttag agttgctgaa
     9721 gcttaagttg ggtatttcaa ccgacttgag agacaagccg ttaaaaaaaa tcatttcaag
     9781 tgtcatcact gaattgaccg ataatctcgg tatcgagctt gttggtgagc gtgctgacca
     9841 tgaaatgttt atcgttgact atgccgctta tcgttatgag ggtggggtgg atatgccacg
     9901 tcaccttcag tggcgactgc ataatttaca gatagcatca aagaaagagg tcaagaatgt
     9961 ggaatcatga aatcacactg atctccaaga aagtaacagg taaggataag ttactacaac
    10021 caatctctga agatgttgaa gttactctct tatgtcgcaa aaagagggtc actcgctctg
    10081 aattttatca ggcgaatcag gtagggctta aaccgagctt ggtcgttgag attcgaaatt
    10141 ttgagtatga gaatcaagag cttgcgaagt tcgaaggcaa gcaatatcat atcttgaaaa
    10201 cctatcctat tgattctgaa attttagagt tgactttgtc agaggtgttg aaatgagtaa
    10261 tgaccttgct gatttgatag cgaaagagct tgcagcttac tctgatgagg ttactgaaga
    10321 agtggataag attgcagagc aagtgactga tgagactgtg gatgagttga aagagacaag
    10381 tccgaaacgg tacggaaagt atcgtagaag ttggaaaaag aagaagttgg ccaatggctc
    10441 ttttgttgtg ttcaacgcag ttgcaagtct tactcacata cttgaaaacg ggcacctttc
    10501 aagaaatggt ggtcgtgtcg ctggtatcgt ccacatcaag ccagctgaag aaaaagcaat
    10561 tcagaacttt gagaagcgaa tcaaggagat tgggaaatga agctatcaga ctttgctgct
    10621 attttggaac aggcaaactt gcctgtcact tatcgagcgt ttaaaattgg aaacgctcct
    10681 gacctacctt atctggtcta ttatgaatca agtccagtca tcaattcagc tgacaacacg
    10741 gttaatcatc agattaagag cgtgacagtt gagctggctt ttgagagtaa ggatgaagat
    10801 ttggaagaac gtctggaaga gctgtgggca aaccacaagc tcttttttga agttcaagaa
    10861 gaaacattta tcgagactga aagactctat gtcaagtctt acacagtcta tctatactaa
    10921 ggaggaatga catgactcaa gaaaataaag taacctttgg cctagaaaat gtacatatcg
    10981 cacctatcaa gacacttgca gcagatggag ttatcactta cggcgatgtt tttcgttttc
    11041 ctggagcaat agagctgata cttgatacta aaggggaaac aacccctatc aaagcagaca
    11101 acaaggatta ccatttcatg aattcaaacg aaggatatga gggtaaactt aaaatcccac
    11161 acatcattga tgaatttgcg acaaaaattc ttggtgaaat caaggaccct caaactggtg
    11221 ttatgactga aaaagcagat gcgagcttga cagagttcgc aatgatgttc cagtttgaag
    11281 gcgacaaaaa caagactcgc tatgtgatgt actactgttt tgccagtcgc ccatctcttg
    11341 gctcaaaaac taagaacggg acatcaacca acgaacgtga acttagtttc aaagctagcc
    11401 cgcgtccatt ggatacagtt gtcaagcgtt ctatcacatc agctgatgac aaggatgcgt
    11461 atgacaactg gttcaagaaa gtgtatgaac ctactgcagt tgcagcttaa ggagaagatc
    11521 tatgcgtaaa atcgttttgg ttggtgatca ggagtatgag ttggggacca acggctatac
    11581 tcctattgct tacaagcaac aatttggaaa agattatttt caagatttgt tctcgatgtt
    11641 gaaaaatcaa tcattcatga atgaattgaa caagttggaa accgacaagg aattgacagc
    11701 gactaatatt gatatttcga tgttgtcaga ttttgacatg acctttttca accgtctttt
    11761 ttggaccttt gctaaatctg caaatcctca catcaagcct tatgaacaat tcttcatgga
    11821 aatggaaatc ttcccgattc aggaagttgg acctgtgctg atggaaatgc taaatgcgag
    11881 catgacgaca aaaaagcacc agatgagtca gaatcagcta gcgaagaaat cttcacagta
    11941 gaatcctatc tatcttgctg taaagaaact ggtctttcta ttgatgatct aaagcacatt
    12001 tcaatcggaa tggctctgga ttatcagacg gattatgtga atctacggag cgaggataag
    12061 ggtggcgaac ggaaagccac gcaagctgat tttgacagtt tttaaagaaa aatgagtgct
    12121 gagagagcga ttctgagacc aagttccttg gtctggctgc attatcagtg gtagaagttc
    12181 tctcagcgct tttctatttt tttgagaaag gaggaaatat ggcaggaaat atcaaaggta
    12241 tcaaaattga aatcgatggc gacacgcaac ccttgcagaa ggcgctgaaa aatgtcaata
    12301 aggccgctac tgatgcaagt caggagttga gacagattga caaggccttg aaatttgata
    12361 cagggaacgt aacgctcctg actcagaaac aagaggtctt acaaaagcaa gtttcgacga
    12421 ccaaggagaa actggaaacc ttgagacaag ctcagtctca ggtggaacag cagttcaaaa
    12481 atggtgatat cggtgctgat cagtaccgtg cctttcaacg cgaagtcgaa gttactcaaa
    12541 acgtcctaaa aggatatgag ggtaagcttg caaatgtgaa tcaggcgctt aatgagaatg
    12601 ggagtgctac tcagaacaac aagaaccaat taaaagagtt gcaaaatgag cagagtcaac
    12661 ttgcttcaga gatgagtaag gtgacaagtt cattcaaact gcaagaaagc gctttgggtt
    12721 caaatgctag tgaagccgag agaaatgctc ttgcccagaa aaagattggt gcccagtctg
    12781 agattgtaag taaacagatt tcaaatctag aacagcaatt ggaaatcact aaaaaagaat
    12841 ttggtgagaa ctccacacaa gccaacaaga tggaatctga gctaaatcag gctaagactg
    12901 cttttaatca tctcaatgat gagatgaagg gaacaaagtc tgctgctgat agcactcaag
    12961 aaagtttaag tgaaatctca agaaatttaa gagcagaact acttcaacag tttagtgaga
    13021 agttgagtgc tatttcagaa aagcttgtgg aagtaggaaa agaagcgtta gaagcagctg
    13081 ctcaaatgca agctagtaat gctcaattta ctaccgtttt cggagatatg gaaacccaag
    13141 caagagaagc gttgaatgct attggtcagg aaatggatat tgtcccagag cgtttacaag
    13201 ggtcatttac tcagatggct tcatttgcta aaacttcagg actagacact gcgcaagcat
    13261 tggacctgac ttcccgtgca actagggcag cggcggatgg cgcagctttt tacgacaagt
    13321 ccatcgagag cgtatcagaa agcctacaat ctttcctgaa aggaaacttt gctaacgatg
    13381 ccgctcttgg aatctctgcg acagaaacga ccaggaatgc agctgcaaat aaattgtacg
    13441 gaaagtcatt caaggacttg agcgaagcgc agaagcaatt gaccttgctt cagatggtcg
    13501 aagacggaaa taaactctca ggagctcttg gacaggctgc aagagaatca gacggcctag
    13561 aaaacgtgat ggggaatctg aaacaagctg ggaccaatgc attatctgct attggtcaac
    13621 ctcttctaga aatgatgatt cctgtttttc aaaccttggc aacgattgtg aaaggtgtgg
    13681 ccgagctgtt caattccttg cctgatccag taaaagattt tgttgttatt ttaggaacag
    13741 ttgtgactgc tgtaggggtc atagccccca tattcttaac cttgcaagcc cttgctgagt
    13801 ttttaaaaat atctattgga gaaatgataa ttgccgcatt gccaattatt ggaacagcta
    13861 ttgcaattgc tgctgcagtt gctgcaatta ttgttattgt aaaatatctc tgggaaacta
    13921 acgaaggttt tcgagatgcg gtcacgaccg tttggaatgc tatactagcc gttatcaata
    13981 cagttgtttc agaaatctct gatttcatca tgagtatatt cgggacggtt gttacttggt
    14041 ggacggagaa ccaggaactt atcaggacaa gtgctgagac tgtctggaat gccatttata
    14101 cggtcatcag tacaatactg gatatacttg gccccttgct ccaagctggc tgggataaca
    14161 ttcaactgat cattacaaca acttgggaaa tcatcaagat cgttgttgag actgcaatca
    14221 atgttgtcct tggtgttatc caagcagtta tgcagatcat tactggtgat tggtcaggag
    14281 cttgggaaac tatcaaggga gtgttttcta ctgtatggca agctattcaa agcattgttc
    14341 agactatttt ctcagctatc cagagttata tttcaaatat tctcaacggc atttcaggaa
    14401 ctgtatcaaa tatctggaac agcatcaagg acactgtctc aaatgtgtta aatgctatat
    14461 ctagtactgt atcaagtgtt tgggaaggta tcaagagtac catttcaagt gctatcaatg
    14521 gtgcaaggga tgctgtttct tcagctattg aagccatcaa aggattgttt aacttcaaca
    14581 tcagctggcc acatatccca ctacctcact tttacgtgag tggttcggcc aatccattag
    14641 attggttgag tcaaggtgtt ccaagtattg gaatcgaatg gtatgccaaa ggcggtatca
    14701 tgacgaaacc aactatcttt ggaatgaatg gtaataacat aatggttggt ggtgaagctg
    14761 ggaatgaagc agtattgcca cttaacgaca aaacgcttgg agccatcggt cgaggtatcg
    14821 ctcaaactat gggtggaact tcaccaacca tcaacattac tattactggt aacaccgtca
    14881 gagaagaagc tgacatcagt cggattgctg atgaggtggc tcagcgtatt gctgacgaat
    14941 tacaacgtag gagacaattg agaggagggt ttgcatgata aagcataatg agcttgtgat
    15001 tgacggtgtg aggacatcgt cttttccatt taagatcatt gtccatgact ctccttcaat
    15061 cgctctagga gagagcaaga cagctctctt ggagcatggt ggtgtcagtg gggcaatcgt
    15121 tcagacaaac aagcataggg aactggtcaa gaaaacttat acgatttact tggtcaaacc
    15181 tactgaagaa cagatgaacc aatttatgag tctgtttatc cgtgaaaagt tctggctaga
    15241 gagtgagcga gtcaaaacaa ctcgtctttg gtgctataag gtcaatgtga gcgaccttga
    15301 agaagtgcaa cctggtcttt acatgaccaa agcaaccttc acttgccatc ctacaaaata
    15361 ctttaaagac tccgatacac agagattgac aagaagtggg actttgaccg ttcaaggttc
    15421 tgctcttgcc tttcctaaaa tcacaatcgt tggtcagagc gcttctgaaa cttcatttac
    15481 aattgctggt caggtcattc gtcttgaacg actcactgag tcgcttgtga tggttaataa
    15541 tcctgacaat ccaagtttta aaacaacaac agggaagcca gtcaaatggt caggggattt
    15601 tatcacagtt gatccagcga aagtgaagaa tattggggtt gttttaggcc caggtattca
    15661 atcgattgaa atcgaaacgg tttgggggtg ggcataattg ctttatctac ttaataaaga
    15721 tgtaagaacc gttcgatgga acggggagcc acttcatgaa gcgacttcgg cgattgtgaa
    15781 agaaactatg aatggcgatt ttaccttgac tgtgaaatat cctatttctg attctggtat
    15841 ttaccagctc atccaagaag atatgctgat aaaggctccg actcctgtct taggagcgca
    15901 gctatttcgt atcaagaaac ctgttgagca caatgaccat ctggaaatca cagcctatca
    15961 catttcagat gatgtgatgc aacgatctat cacacaaatg agtgtgacta gtcagagttg
    16021 tggcatggct cttgctcgca tggtacaaaa caccaaaacg gctcttggag acttctcatt
    16081 caacagtgat atccaggacc gtaggacatt caacacgact gagacagaaa ccctgtactc
    16141 tgtattgctg gacggcaagc atagtatcgc cggaacgtgg gaaggcgagc tggtgcgtga
    16201 taactttgcg atgactgtaa agaagagtcg tggtgagaat cgtggtgttg ttattacaac
    16261 acataagaat ctgaaggact accaacgaac caaaaacagt caaaatgttg ttacaaggat
    16321 tcatgctcga tccacattta agcctgaagg tgctgaaaag gaaacaacta tcagagtgac
    16381 tgttgatagt cctcttatta attcttatcc ttatataaac gaaaaagagt atgagaacaa
    16441 caacgcaaaa tccgttgaag agttgcagaa gtgggcacag tctaagttct caaatgaggg
    16501 aattgacaag gtctctgatg ctatcaaaat tgaagcttat gaacttgatg ggcaagtggt
    16561 ccatatgggc gacacggtca atctcaagag ctggaaacat aatgtcgatg cattcaagaa
    16621 agctattgct tatgagttcg atgccttaaa agaagaatac atctctctga ctttcgatga
    16681 taaggcaggt attggtggtt ctagatcttc tggtggccta tctagcgcag ccgatgcaat
    16741 tcttggagtg acagaatctg cacaagaaat cgcccttgaa aaggctcttc aaaatgctga
    16801 cttagacttt gatcataagg ctggattgct tagacaggaa atttctgacg atattgaact
    16861 ggccaaagcc agagctgaag aagtcaagag agaactgtct gacactatca atcagcgatt
    16921 taatagcttt gacaacgggc cattga
//
LOCUS       DAVBOD010000045        16842 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 640-05
            SAMEA1012484-rid20186543.denovo.045, whole genome shotgun sequence.
ACCESSION   DAVBOD010000045 DAVBOD010000000
VERSION     DAVBOD010000045.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012484
            Sequence Read Archive: ERR059358
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 16842)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16842)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979948.1
            Genome Coverage       :: 595x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:03:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,266
            CDSs (total)                      :: 2,219
            Genes (coding)                    :: 2,091
            CDSs (with protein)               :: 2,091
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 71 of 128
            Pseudo Genes (incomplete)         :: 50 of 128
            Pseudo Genes (internal stop)      :: 33 of 128
            Pseudo Genes (multiple problems)  :: 22 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16842
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012484-rid20186543.denovo.045"
                     /strain="NIG 640-05"
                     /db_xref="taxon:1313"
     gene            <1..120
                     /locus_tag="VQ862_001571"
     CDS             <1..120
                     /locus_tag="VQ862_001571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS5/IS1182 family transposase"
                     /protein_id="HET3115889.1"
                     /translation="IFAKVKTFKMFSTTYRNHRKRFGLRMNLSAGIINHELGF"
     gene            169..633
                     /locus_tag="VQ862_001572"
     CDS             169..633
                     /locus_tag="VQ862_001572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001146193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldose epimerase"
                     /protein_id="HET3115890.1"
                     /translation="MGGHPGFNCLLLDDEVYEDYYLEFEKEEICSVPRPFPETGMLDF
                     QDRSPWLEGQKEIDLSYDLFSTDAVTLDELQSRTIALRSLKHDKGLKVHFAEFPNLII
                     WSTLNKGPFITFEPWSGLSTFLEEGDHLEDKKNVCLLEANQVEELGFEIEVL"
     gene            791..1216
                     /gene="lacA"
                     /locus_tag="VQ862_001573"
     CDS             791..1216
                     /gene="lacA"
                     /locus_tag="VQ862_001573"
                     /EC_number="5.3.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacA"
                     /protein_id="HET3115891.1"
                     /translation="MSIVIGADAAGLRLKEVVKDFLEKENFHLVDVTAEGQDFVDVTL
                     AVAAEVNKEEQNLGIVIDAYGAGPFMVATKIKGMVAAEVSDERSAYMTRGHNNSRMIT
                     MGAQLVGDELAKNIAKGFVNGKYDGGRHQIRVDMLNKMC"
     gene            1247..1762
                     /gene="lacB"
                     /locus_tag="VQ862_001574"
     CDS             1247..1762
                     /gene="lacB"
                     /locus_tag="VQ862_001574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacB"
                     /protein_id="HET3115892.1"
                     /translation="MRIAIGCDHIVTDEKMAVSEFLKSKGYEVIDFGTYDHTRTHYPI
                     FGKKVGEAVTSGQADLGVCICGTGVGINNAVNKVPGVRSALVRDMTTALYAKEQLNAN
                     VIGFGGKITGELLMCDIIEAFIHAEYKPSEENKKLIAKIEHLESHNAQQTDANFFTEF
                     LEKWDRGEYHD"
     gene            1773..2702
                     /locus_tag="VQ862_001575"
     CDS             1773..2702
                     /locus_tag="VQ862_001575"
                     /EC_number="2.7.1.144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000604270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-6-phosphate kinase"
                     /protein_id="HET3115893.1"
                     /translation="MILTVTMNPSIDISYPLDELKIDTVNRVVDVTKTAGGKGLNVTR
                     VLSEFGDSVLATGLVGGKLGEFLVEHIDNQVKKDFFSIQGETRNCIAILHGDNQTEVL
                     EKGPEVLEQEGQDFLEHFKKLLESVEVVVISGSLPAGLPVDYCASLVELANQAGKPVV
                     LDCSGAALQAVLESPHKPTVIKPNNEELSQLLGREVSEDLDELKEVLQEPLFAGIEWI
                     IVSLGANGTFTKHGDTFYKVDIPRIQAVNPVGSGDSTVAGISSGLLHKESDAELLIKA
                     NVLGMLNAQEKMTGHVNMANYQALYDQLIVKEV"
     gene            2704..3684
                     /gene="lacD"
                     /locus_tag="VQ862_001576"
     CDS             2704..3684
                     /gene="lacD"
                     /locus_tag="VQ862_001576"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001229146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
                     /protein_id="HET3115894.1"
                     /translation="MALTEQKRVRLEKLSDENGIISALAFDQRGALKRLMAQHQTEEP
                     TVAQMEELKVLVADELTKYASSMLLDPEYGLPATKALDEKAGLLLAYEKTGYDTTSTK
                     RLPDCLDVWSAKRIKEEGADAVKFLLYYDVDSSDELNQEKQAYIERIGSECVAEDIPF
                     FLEILAYDEKIADAGSVEYAKVKPHKVIGAMKVFSDPRFNIDVLKVEVPVNIKYVEGF
                     AEGEVVYTREEAAAFFKAQDEATNLPYIYLSAGVSAKLFQDTLVFAHESGANFNGVLC
                     GRATWAGSVEAYIKDGEAAAREWLRTTGFENIDELNKVLQTTATSWKERV"
     gene            3918..4754
                     /locus_tag="VQ862_001577"
     CDS             3918..4754
                     /locus_tag="VQ862_001577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000285719.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HET3115895.1"
                     /translation="MYRILNPMNHNVSLVRNDKGEEVIVIGKGIAFGKKKGDLIAENQ
                     VEKIFRMKTEESRENFMALLKDVPLDFITVTYEIIDKLSKKYHYPIQEYLYVTLTDHI
                     YCSYQALTQGRYKDSNLPDISAKYPVAFQIANEAFEIYRQKLADHFPEDEIIRIAYHF
                     INAEGENEVELVESIDKRKEILRNVEEVLTDYAIQRTKKNNHFYDRFMIHLNYFLDYL
                     DRSRDDNQSLLDMEDHIKQSYPKAFEIGSKIYDVITQHTGLDLYKSERVYLVLHIQRL
                     LS"
     gene            4790..5107
                     /locus_tag="VQ862_001578"
     CDS             4790..5107
                     /locus_tag="VQ862_001578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HET3115896.1"
                     /translation="MNREEVTLLGFEIVAYAGDARSKLLEALKAAEAGDFEKADALVE
                     EAGSCIAEAHHAQTSLLTKEASGEDLAYSVTMMHGQDHLMTTILLKDLMHHLIELYKR
                     GVK"
     gene            5107..6798
                     /locus_tag="VQ862_001579"
     CDS             5107..6798
                     /locus_tag="VQ862_001579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001037357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HET3115897.1"
                     /translation="MNKLIAFIEKGKPFFEKLSRNIYLRAIRDGFIAGMPVILFSSIF
                     ILIAFVPNSWGFKWSDEVVAFLMKPYSYSMGILALLVAGTTAKSLTDSVNRSMEKTNQ
                     INYMSTLLAAIVGLLMLAADPIESGLATGFLGTKGLLSAFLAAFVTVAIYKVCVKNNV
                     TIRMPDEVPPNISQVFKDVIPFTLSVVSLYALDLLARHFVGSSVAESIGKFFAPLFSA
                     ADGYLGITIIFGAFAFFWFVGIHGPSIVEPAIAAITYANAEVNLNLLQQGMHADKILT
                     SGTQMFIVTMGGTGATLVVPFMFMWLTKSKRNRAIGRASVVPTFFGVNEPILFGAPLV
                     LNPIFFIPFIFAPIANVWIFKFFIETLGMNSFTANLPWTTPAPLGLVLGTNFQVLSFI
                     LAALLIVVDVVIYYPFLKVYDEQILEEERSGKSNDELKEKVAANFNTAKADAILEKAG
                     VDAAQNTITEETNVLVLCAGGGTSGLLANALNKAAAEYNVPVKAAAGGYGAHREMLPE
                     FDLVILAPQVASNFEDMKAETDKLGIKLAKTEGAQYIKLTRDGKGALAFVQEQFD"
     gene            7013..8419
                     /gene="lacG"
                     /locus_tag="VQ862_001580"
     CDS             7013..8419
                     /gene="lacG"
                     /locus_tag="VQ862_001580"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HET3115898.1"
                     /translation="MTKTLPKDFIFGGATAAYQAEGATHTDGKGPVAWDKYLEDNYWY
                     TAEPASDFYNRYPVDLKLAEEYGVNGIRISIAWSRIFPTGYGQVNVKGVEFYHNLFAE
                     CHKRHVEPFVTLHHFDTPEALHSNGDFLNRENIEHFVDYAAFCFEEFPEVNYWTTFNE
                     IGPIGDGQYLVGKFPPGIQYDLAKVFQSHHNMMVSHARAVKLYKDKGYKGEIGVVHAL
                     PTKYPLDPKNPADVRAAELEDIIHNKFILDATYLGRYSAETMEGVNHILSVNGGSLDL
                     REEDFTTLEAAKDLNDFLGINYYMSDWMEAFDGETEIIHNGKGEKGSSKYQIKGVGRR
                     VAPDYVPRTDWDWIIYPQGLYDQIIRVKKDYPNYKKIYITENGLGYKDEFVDNTVYDD
                     GRIDYVKQHLEILSDAIADGANVKGYFIWSLMDVFSWSNGYEKRYGLFYVDFETQERY
                     PKKSAHWYKKVAETQIID"
     gene            8509..8721
                     /locus_tag="VQ862_001581"
     CDS             8509..8721
                     /locus_tag="VQ862_001581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3884 family protein"
                     /protein_id="HET3115899.1"
                     /translation="MNFEKCSQIPCLTSEELKSLGKWYVSTGKEWICHSDDELEEFKN
                     LFLNFINPEEWDTISFDSDFMPFQQS"
     gene            complement(9000..9761)
                     /locus_tag="VQ862_001582"
     CDS             complement(9000..9761)
                     /locus_tag="VQ862_001582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000917571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HET3115900.1"
                     /translation="MLKQEKLTKILEIVNSKGTITVKQIMDEIAVSDMTARRYLQELA
                     DKDLLIRVHGGAEKLRTNSLLTNERSNIEKQALQTAEKQEIAHFAGSLVEERETIFIG
                     PGTTLEFFARELPIDNIRVVTNSLPVFLILSERKLTDLILIGGNYRDITGAFVGTLTL
                     QNLSNLQFSKAFVSCNGIQNGALATFSEEEGEAQRIALNNSNKKYLLADHSKFNKFDF
                     YTFYNVSNLDTIVSDSKLSDSILFKLSKHIKVIKP"
     gene            complement(9943..10905)
                     /gene="nrdF"
                     /locus_tag="VQ862_001583"
     CDS             complement(9943..10905)
                     /gene="nrdF"
                     /locus_tag="VQ862_001583"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004253599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit beta"
                     /protein_id="HET3115901.1"
                     /translation="METYYKAINWNAIEDVIDKSTWEKLTEQFWLDTRIPLSNDLDDW
                     RKLSNKEKDLVGKVFGGLTLLDTMQSETGVQALRADIRTPHEEAVFNNIQFMESVHAK
                     SYSSIFSTLNTKAEIEEIFEWTNTNPYLQKKAEIVNEIYLNGSPLEKKVASVFLETFL
                     FYSGFFTPLYYLGNNKLANVAEIIKLIIRDESVHGTYIGYKFQLGFNELPEEEQEKLK
                     EWMYDLLYTLYENEEGYTESLYDGVGWTEEVKTFLRYNANKALMNMGQDPLFPDSAED
                     VNPIVMNGISTGTSNHDFFSQVGNGYLLGEVEAMQDDDYNYGLD"
     gene            complement(11093..13252)
                     /gene="nrdE"
                     /locus_tag="VQ862_001584"
     CDS             complement(11093..13252)
                     /gene="nrdE"
                     /locus_tag="VQ862_001584"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000523276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit alpha"
                     /protein_id="HET3115902.1"
                     /translation="MGLKHLEDVTYFRLNNEINRPVNGQIMLHKDKEALDAFFKENVV
                     PNTMVFDSIKDKINYLIEHNYIETAFIKKYRPEFLEELAQFIKDQNFQFKSFMAAYKF
                     YNQYALKTNDGEYYLENMEDRVFFNALYFADGNEAVAIDIANEIIHQRYQPATPSFLN
                     AGRARRGELVSCFLIQVTDDMNSIGRSINSALQLSRIGGGVGITLSNLREAGAPIKGY
                     EGAASGVVPVMKLFEDSFSYSNQLGQRQGAGVVYLNVFHPDIIAFLSTKKENADEKVR
                     VKTLSLGVVVPDKFYELARKNEEMYLFSPYSVEKEYGVPFNYIDITEKYDELVANPNI
                     RKTKIKARDLETEISKLQQESGYPYVVNIDTANRANPVDGKIIMSNLCSEILQVQEPS
                     LINDAQEFLQMGTDVSCNLGSTNVVNMMTSPDFGRSIRAMVRALTFVTDSSHIVAVPT
                     IDHGNSQAHTFGLGAMGLHSYLAQQLIEYGSPESVEFTSIYFMLMNYWTLVESNNIAR
                     ERGITFHNFEKSDYANGSYFDKYVTGEFVPTSDRVKELFKNVFIPGVADWAELRDKVQ
                     EDGLYHQNRLAVAPNGSISYINDVSASIHPITQRIEERQEKKIGKIYYPAAGLSTETI
                     PYYTSAYDMDMRKVIDVYAAATEHVDQGLSLTLFMRSDIPKGLYEWKRENKQTTRDLS
                     ILRNYAFNKGIKSIYYVRTFTDDGGEVGANQCESCVI"
     gene            complement(13333..13551)
                     /gene="nrdH"
                     /locus_tag="VQ862_001585"
     CDS             complement(13333..13551)
                     /gene="nrdH"
                     /locus_tag="VQ862_001585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000259243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaredoxin-like protein NrdH"
                     /protein_id="HET3115903.1"
                     /translation="MVTVYSKNNCVQCKMTKRFLDSNNVSYREINLDEQPEYVDQVKE
                     LGFSAAPVIQTPTEVFSGFQPGKLKQLA"
     gene            13902..14165
                     /locus_tag="VQ862_001586"
     CDS             13902..14165
                     /locus_tag="VQ862_001586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019775469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphocarrier protein HPr"
                     /protein_id="HET3115904.1"
                     /translation="MASKDFHVVAETGIHARPATLLVQTASKFASDITLEYKGKSVNL
                     KSIMGVMSLGVGQGADVTISAEGADADDAIAAISETMEKEGLA"
     gene            14171..15904
                     /gene="ptsP"
                     /locus_tag="VQ862_001587"
     CDS             14171..15904
                     /gene="ptsP"
                     /locus_tag="VQ862_001587"
                     /EC_number="2.7.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate--protein phosphotransferase"
                     /protein_id="HET3115905.1"
                     /translation="MTEMLKGIAASDGVAVAKAYLLVQPDLSFETITVEDTNAEEARL
                     DAALQASQDELSVIREKAVGTLGEEAAQVFDAHLMVLADPEMISQIKETIRAKKVNAE
                     AGLKEVTDMFITIFEGMEDNPYMQERAADIRDVTKRVLANLLGKKLPNPASINEEVIV
                     IAHDLTPSDTAQLDKNFVKAFVTNIGGRTSHSAIMARTLEIAAVLGTNNITEIVKDGD
                     ILAVNGITGEVIINPTDEQAAEFKAAGEAYAKQKAEWALLKDAQTVTADGKHFELAAN
                     IGTPKDVEGVNNNGAEAVGLYRTEFLYMDSQDFPTEDEQYEAYKAVLEGMNGKPVVVR
                     TMDIGGDKELPYFDMPHEMNPFLGFRALRISISETGDAMFRTQIRALLRASVHGQLRI
                     MFPMVALLKEFRAAKAVFDEEKANLLAEGVAVADNIQVGIMIEIPAAAMLADQFAKEV
                     DFFSIGTNDLIQYTMAADRMNEQVSYLYQPYNPSILRLINNVIKAAHAEGKWAGMCGE
                     MAGDQQAVPLLVGMGLDEFSMSATSVLRTRSLMKKLDTAKMEEYANRALTECSTMEEV
                     LELQKEYVNFD"
     gene            16159..>16842
                     /gene="phtA"
                     /locus_tag="VQ862_001588"
     CDS             16159..>16842
                     /gene="phtA"
                     /locus_tag="VQ862_001588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtA"
                     /protein_id="HET3115906.1"
                     /translation="MKINKKYLVGSAAALILSVCSYELGLYQARTVKENNRVSYIDGK
                     QATQKTENLTPDEVSKREGINAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDAIFSEE
                     LLMKDPNYKLKDEDIVNEVKGGYVIKVDGKYYVYLKDAAHADNVRTKEEINRQKQEHS
                     QHREGGTPRNDGAVALARSQGRYTTDDGYIFNASDIIEDTGDAYIVPHGDHYHYIPKN
                     ELSASELAAA"
BASE COUNT         5247 a         3035 c         3491 g         5069 t
ORIGIN      
        1 atctttgcca aagtaaaaac gtttaaaatg ttttcaacaa cctatcgaaa tcatcgtaaa
       61 cgcttcggat tacgaatgaa tttgagtgct ggtattatca atcatgaact aggattctag
      121 ttttgcagga agtctaataa agaaactagc aaggtcaggc cttactttat tggtggacat
      181 ccaggattta attgtcttct acttgatgat gaagtctatg aagattatta tctagagttt
      241 gagaaagaag agatttgctc tgttccacgt cctttcccag aaacaggtat gttggatttc
      301 caagatagaa gtccatggct agagggacaa aaagaaatag atcttagtta tgatcttttc
      361 agcacagatg cagtgacttt ggatgaattg caatctcgaa caattgccct tcgttctctt
      421 aaacatgata agggattgaa agtgcatttt gcagaatttc caaacctcat catctggtca
      481 actttgaaca agggaccttt cattaccttt gaaccatggt ctggcttgtc aacattcctt
      541 gaagaaggag atcatttaga agataagaag aatgtttgtc tcttagaagc caatcaggtt
      601 gaagaattag ggtttgagat agaagtttta taaaaaaagt aaaaaataaa taacaaaaac
      661 aaacacaaac tgttgacttc ttcaaacaat agtagtatat tatgtttgtg aggactaatt
      721 gactgttttt taaagacagc caatacactg ctggaatcca gcatagaaaa aataaaaagg
      781 agtatacaat atgtctattg ttatcggtgc agatgctgca ggtttgagat tgaaagaagt
      841 tgtgaaagac ttcttagaaa aagaaaactt ccaccttgtg gatgttacag ctgaaggtca
      901 agactttgtt gatgtgactc tcgctgttgc tgcagaagta aacaaagaag aacaaaacct
      961 tggtatcgtg attgatgctt atggagctgg tccatttatg gttgcaacta agatcaaagg
     1021 aatggttgct gcagaagtat ctgacgaacg ttcagcttat atgactcgtg gccacaacaa
     1081 ctcacgtatg atcactatgg gggcacaact tgttggtgat gaattggcta aaaacatcgc
     1141 taaaggattt gttaatggta aatacgacgg tggtcgtcac caaatccggg ttgacatgtt
     1201 gaacaaaatg tgctaattag attatagtaa gaaaggtaag ttaaaaatga gaattgcaat
     1261 tggatgtgac cacatcgtaa cagatgaaaa aatggcggtt tcagaatttt tgaaatcaaa
     1321 aggatatgaa gtcattgact ttggtaccta tgaccataca cgtactcact acccaatctt
     1381 tggtaaaaaa gtaggggaag cagtaactag tggtcaagct gatctcgggg tatgtatctg
     1441 tggtactggt gttggtatca acaacgctgt aaataaagtt ccaggtgttc gttctgcctt
     1501 ggttcgtgat atgacaacag ccctttatgc taaagaacaa ttgaacgcca acgttatcgg
     1561 ttttggtggt aagattactg gtgaattgct tatgtgtgat atcatcgaag ctttcattca
     1621 tgctgaatac aaaccatctg aagaaaacaa aaaattgatt gcgaaaattg aacaccttga
     1681 aagtcacaat gctcaacaaa cagacgcaaa cttcttcact gaattccttg aaaaatggga
     1741 tcgtggagaa taccacgact aagaggtaac ctatgatttt aacagttaca atgaacccat
     1801 ccattgatat ttcctatccc ttggatgagt tgaagattga tactgtcaat cgtgtggtgg
     1861 atgtaaccaa aacggctggt ggtaagggac tcaatgttac ccgagtactt tcagaatttg
     1921 gcgattctgt tcttgctact ggtttagtgg gtggcaaact tggtgagttt ttggttgaac
     1981 atatcgataa tcaagtaaag aaagatttct tctcaattca gggagaaact cgtaactgta
     2041 tcgctattct ccacggagac aaccaaacag aagttcttga aaaaggtcct gaagtattgg
     2101 aacaggaagg tcaagacttt ttggaacatt tcaaaaaact cttggagtca gttgaagtag
     2161 tggtcatctc aggtagtctg ccagctggcc ttccagttga ttactgtgcg agcttggtag
     2221 aacttgctaa tcaagctggc aagcctgtag tcttggactg ctcaggtgca gcacttcagg
     2281 ctgttcttga atcaccccat aaaccaacag tcatcaaacc aaataatgaa gaattgtctc
     2341 agcttcttgg aagagaagtt tctgaggatt tggatgaatt aaaagaagta cttcaagaac
     2401 ctttgtttgc agggattgaa tggattatcg tttcacttgg tgccaacggt acttttacca
     2461 aacatggtga cactttctac aaggtagata ttcctagaat tcaggcggta aatcctgttg
     2521 gatctggaga ctctactgtg gcaggaattt cttcaggact tcttcacaaa gaatcggatg
     2581 cagaattact catcaaggca aatgtccttg gtatgctcaa tgctcaagaa aaaatgactg
     2641 gtcatgtcaa catggccaac tatcaagctc tatatgatca attaatagta aaagaggtat
     2701 aaaatggctt taacagaaca aaaacgtgta cgcttagaaa aactttctga tgaaaatggt
     2761 atcatctcag ctcttgcatt tgaccaacgt ggtgctttga aacgcctcat ggctcaacac
     2821 caaacagaag aaccaactgt ggcccaaatg gaagaactta aagttttggt agcagatgaa
     2881 ttgactaaat acgcttcatc tatgcttctt gaccctgagt atggacttcc agcaactaaa
     2941 gctcttgatg aaaaagctgg tcttctcctt gcttatgaaa aaacaggtta tgacacaaca
     3001 agcacaaaac gcttgccaga ctgcttggat gtttggtctg caaaacgtat taaagaagaa
     3061 ggtgcagatg cagttaaatt cttgctttac tatgatgtag atagctcaga cgaactcaat
     3121 caagaaaaac aagcctacat cgaacgcatc ggttctgagt gtgtggctga agatatccca
     3181 ttcttccttg aaatccttgc ttacgatgaa aaaattgcag acgcaggttc tgtagaatac
     3241 gctaaagtaa aaccacacaa agttatcggt gctatgaaag tcttttcaga cccacgcttt
     3301 aacattgatg tcttgaaagt tgaagttcct gttaacatta aatatgttga aggcttcgct
     3361 gagggtgaag tggtttacac acgtgaagaa gcagcagcct tcttcaaagc gcaagatgaa
     3421 gcaacgaact tgccatacat ctacttgagt gctggtgtat cagctaaact cttccaagat
     3481 actcttgtat ttgctcatga atcaggtgca aactttaacg gagttctttg tggccgtgct
     3541 acatgggcag ggtcagttga agcttacatc aaagatggtg aagcagcagc tcgcgaatgg
     3601 cttcgcacaa ctggatttga aaacattgat gagctcaata aagttcttca aacaacagcg
     3661 acttcatgga aagaacgtgt gtaagaaagt cctcctagtt taggaacatg aatctaaaaa
     3721 aatttaaaaa aagttgtatg taaaggttta caaaataact tacttgtgct atacttaaat
     3781 cacaagttaa tacaaggtga gtgttactaa gtaatattag gcatgatcac aggtgaatta
     3841 gaaatcagct gattttctag ttcatttgtg gtcatttttt gtactcatat acctttaaaa
     3901 tataaaagga ggttgacatg tatcgaattc taaatccaat gaatcacaat gtctcgcttg
     3961 tcagaaatga taagggagaa gaggtgattg taattggtaa ggggattgca ttcggaaaga
     4021 agaaggggga tttgattgct gaaaatcagg ttgagaaaat ctttcggatg aagaccgaag
     4081 agtccagaga aaactttatg gctcttctca aagatgttcc gcttgatttt atcacagtga
     4141 cctatgaaat tattgataag ctatcaaaga aatatcatta tccgattcaa gagtatctct
     4201 atgtaacctt gacagatcat atttactgtt cttatcaagc tctaactcaa ggaaggtaca
     4261 aggatagtaa tctgccagat atttccgcta agtatcctgt cgcttttcaa atcgcaaatg
     4321 aagcttttga aatttaccgt cagaagctag cagatcattt tcctgaggac gaaattattc
     4381 ggattgctta tcatttcatt aatgctgaag gtgaaaatga agtggaactt gtggagtcga
     4441 ttgataagag gaaagaaatt ctcaggaatg ttgaagaagt tttaacggac tatgcaattc
     4501 aacgaactaa aaagaataac catttctatg atcgctttat gatccatttg aattatttct
     4561 tggattattt agacagatct agagatgata accaatcact tctggatatg gaagatcata
     4621 ttaaacaatc ctatccaaaa gccttcgaga ttggttccaa gatctatgat gtgattacgc
     4681 aacatacggg tcttgatttg tataaaagtg aacgagttta tctagttcta catatccaac
     4741 gtttattgtc ataaaaattt atttaaaact atataaggag aattctatca tgaatagaga
     4801 agaagtaaca ttgttaggtt ttgaaatcgt agcctatgct ggcgatgctc gttcaaaact
     4861 attggaagcc ttgaaggctg ctgaagctgg tgattttgaa aaagcggacg ctctggtaga
     4921 ggaagctggt agctgtattg cagaggctca ccacgcgcaa acaagtctat tgactaagga
     4981 agcttctggt gaggacttag cgtatagtgt gaccatgatg catggtcaag atcacttgat
     5041 gacaactatc ttgttaaaag acctaatgca ccatttaatt gaactttaca agagaggagt
     5101 taaataatga ataaactaat tgcatttatc gagaaaggaa agcctttctt tgaaaaacta
     5161 tctcgtaata tctatcttcg tgctattcgt gatggtttca ttgcaggtat gcctgttatt
     5221 ctcttctcaa gtatctttat cttgattgcc tttgtaccaa actcatgggg ctttaaatgg
     5281 tctgatgaag ttgtagcctt tctgatgaaa ccttatagct attctatggg tattctggct
     5341 ctcttggtag ctggtacaac agctaagtca ttgactgact cagtaaaccg gagcatggaa
     5401 aaaaccaatc aaatcaacta tatgtcaaca ttgttggcag caattgttgg tttgttgatg
     5461 ttggcagctg atcctatcga aagtggtcta gctactggat tcttgggaac aaaaggtttg
     5521 ctttcagcct tccttgctgc cttcgttact gtagccatct ataaggtctg tgttaagaac
     5581 aacgtcacta ttcgtatgcc tgacgaagtt ccaccaaata tctcacaagt ctttaaagat
     5641 gtgattccat tcactctatc agtggtttct ctttatgctc ttgatttact agctcgtcat
     5701 tttgttggtt ctagtgtggc agaatcaatc ggtaaattct tcgcaccact cttctcagca
     5761 gcagacggat accttggtat taccattatc tttggtgcct ttgccttctt ctggtttgtt
     5821 gggattcatg gtccatctat cgttgaacct gctatcgcag cgattaccta tgcaaatgct
     5881 gaagtcaact tgaaccttct ccaacaaggg atgcatgcag acaagattct tacttctggt
     5941 acacaaatgt ttatcgttac catgggtggt acaggtgcga cattggtcgt tccatttatg
     6001 ttcatgtggt tgacaaaatc gaaacgtaac cgtgcaatcg gacgtgcttc agtagttcct
     6061 accttcttcg gtgtaaatga accaatcttg tttggtgcac ctcttgtttt gaatccaatc
     6121 ttcttcattc catttatctt tgctccaatt gcaaacgtat ggattttcaa attctttatt
     6181 gaaactcttg gaatgaactc attcactgct aatctaccat ggacaactcc agctccacta
     6241 ggtctagttc ttggaactaa cttccaagtg ctatcattca ttcttgctgc ccttctaatt
     6301 gtggttgacg tagttattta ttacccattc cttaaagtct atgatgaaca aattcttgaa
     6361 gaagaacgtt caggtaagtc taatgatgaa ttgaaagaaa aagttgctgc aaacttcaac
     6421 actgcaaaag cggatgctat tcttgaaaaa gcgggtgtcg atgcagcaca aaataccatc
     6481 actgaagaaa caaatgtcct cgttctctgt gctggtggag gtacaagtgg actccttgca
     6541 aatgctttga ataaggcagc agcagaatac aatgtccctg tgaaagcagc agcaggcggc
     6601 tatggtgctc accgtgaaat gttgccagag tttgatttgg ttatccttgc tcctcaagtt
     6661 gcttcaaact ttgaagatat gaaggcagaa acagataagc tcggtattaa acttgctaag
     6721 acagaaggcg ctcaatacat caaattaact cgtgatggaa aaggtgccct agcattcgta
     6781 caagagcaat tcgattaagg ctaggaactg tgaaacagtc tcccatcgtt acggaaatcg
     6841 ctatggcgaa tttcctaatc gccttattaa ttcgtcggta aaaagatatc gtttttacct
     6901 cctcatgtca caattcagtg acttggtaca agaagtgaga tggagaagca tggctcactg
     6961 actcctctcc tctcactttt actttattta aatcaagaaa taggtgaaaa aaatgacaaa
     7021 aacacttcca aaagacttta ttttcggtgg cgcaacagct gcttatcaag cagaaggtgc
     7081 tacacatact gatggaaaag gaccagttgc ttgggataaa tatcttgagg ataactactg
     7141 gtacactgcc gaaccagcta gtgattttta caatcgatat ccagttgacc tcaagctagc
     7201 agaagagtat ggtgtcaatg gtattcgaat ttctattgcc tggtcacgta ttttcccgac
     7261 tggttacggc caagtaaatg ttaaaggtgt tgagttttat cataatttat ttgcagagtg
     7321 tcacaaacgt catgttgagc cctttgtaac tcttcatcac tttgacacgc cagaagctct
     7381 ccattcaaat ggagacttct taaaccgtga aaatatcgaa cattttgtag actacgctgc
     7441 cttctgtttt gaagaatttc cagaagtaaa ctattggaca acctttaatg aaattggacc
     7501 aatcggtgat ggtcaatatt tggttgggaa attccctcca ggtatccagt acgaccttgc
     7561 caaagtcttt caatcacacc acaatatgat ggtgtctcat gcgcgtgcag tcaagctata
     7621 taaagataaa ggctataaag gggaaattgg tgttgttcac gctctgccaa ccaagtatcc
     7681 tttggatcct aaaaatccag cagatgttcg tgcagctgag ttggaagata tcatccacaa
     7741 taaattcatc ttagacgcaa cttatctagg tcgctattca gctgaaacca tggaaggtgt
     7801 caaccatatc ttatcagtca atggtggtag tttggatctt cgtgaagaag attttacaac
     7861 attagaagct gcaaaagact tgaatgattt cctaggaatc aactactata tgagtgactg
     7921 gatggaagcc tttgatggag aaactgaaat tatccataat ggtaaaggtg aaaaaggaag
     7981 ctctaagtat caaatcaaag gtgttggtcg tcgtgtagct cctgactatg taccacgcac
     8041 ggattgggat tggattatct accctcaagg tttgtatgac caaatcatac gtgtgaagaa
     8101 agattatcct aactacaaga agatttacat cactgaaaat ggtctcggct ataaagatga
     8161 gttcgttgat aacactgttt acgatgatgg tcgtattgat tacgtgaaac aacacttgga
     8221 gatcttgtct gatgcgattg cagatggagc taatgtaaaa ggttacttca tttggtcatt
     8281 aatggatgtc ttctcatggt caaacggtta tgaaaaacgt tacggtctct tctacgtaga
     8341 ttttgaaact caagaacgtt atcctaagaa atcagctcac tggtataaga aagtagcgga
     8401 aactcagatt atagactagt agaattagtc attagatata gaattttagt gagtcaaaaa
     8461 gatgttcaaa gattttatcc aatctattta tgaaaaaaag tttatattat aaatttcgaa
     8521 aaatgctctc aaataccgtg tttgacgagt gaagaattga aaagtcttgg aaaatggtat
     8581 gtctcgactg gtaaagaatg gatttgtcat tcagatgatg agctggaaga atttaaaaat
     8641 ctatttttaa attttatcaa tcctgaagaa tgggatacta tctcctttga ttcagatttt
     8701 atgccgtttc aacaatcgta accaatttct caaaaaagtt aaatcttata tttagtactc
     8761 tgtaaaactc ttatctaatc acgttgctta tactcaatga aaatcaaaga gcaactttaa
     8821 actaggaagc gagtcgcaga tttctcaatg catagctttg aggaattggg caaaaagtct
     8881 ttgatataga aaaacgcata gtatcaggtg tttcaacacc tgatattatg cgttttattg
     8941 tgggaagatt tacttttttt cttctgaaat tgagttgtta cccaggctct ttcagtttat
     9001 taaggcttga tgactttaat gtgtttagat agcttaaaaa ggattgaatc acttagttta
     9061 gaatctgaaa caatagtatc aagatttgat acattataaa aagtataaaa atcaaactta
     9121 ttgaacttgc tatgatctgc gagtaaatat tttttattag aattatttaa agcgatgcgt
     9181 tgagcctctc cctcttcctc gctaaaagta gctagagctc cgttttgaat accattacag
     9241 ctaacgaaag ctttagaaaa ttggagatta gagagatttt gtagggtcaa tgtaccaaca
     9301 aaagcacctg taatatcgcg ataatttcca cctattaaaa tcaaatctgt taattttcgt
     9361 tcgcttaaaa tcagaaaaac aggtagactg ttggttacga cgcggatatt gtcaataggc
     9421 aactcacgcg caaaaaactc taatgttgtt cctggtccaa tgaaaatagt ttctctttct
     9481 tctactagac tgcctgcaaa atgggctatt tcttgttttt ctgccgtttg gagggcttgt
     9541 ttttcaatat ttgatcgctc attagtcaaa agggagttgg ttcgaagttt ttcagctcca
     9601 ccatgcacac gaatcagcaa atctttatca gctaattcct gtaaatagcg ccttgcagtc
     9661 atatctgaaa cggctatttc gtccataatc tgtttaactg ttatggttcc tttactattt
     9721 actatctcta aaattttggt taatttttct tgtttgagca tattatcacc tcgtttccta
     9781 ctactatctt accataaaca aactcatcat tcaaatacaa aaacaacaaa atgaaacaaa
     9841 aacaaaaata tcgaagtttg ttttcaaaac tttcgatatt tttgttgggt tataactttg
     9901 atgtttctag tttacttttt gatgattgag agtgatggag aattagtcta aaccgtagtt
     9961 atagtcatcg tcttgcatgg cttcaacttc gccaagaagg taaccatttc cgacttgaga
    10021 gaagaagtca tggttggaag ttcctgttga aataccgttc ataacgattg ggttgacatc
    10081 ttcagctgaa tctgggaaaa gtggatcttg tcccatgttc atgagagctt tattggcatt
    10141 gtagcgaagg aaggttttaa cctcttcagt ccaaccaaca ccgtcataaa gactctctgt
    10201 gtagccttct tcattttcat aaagagtata gagtaggtcg tacatccatt ctttgagttt
    10261 ttcttgctct tcttcaggca attcattgaa accaagttgg aatttgtaac caatgtaggt
    10321 tccgtgaaca gactcgtcac gaataatcaa tttaatgatt tctgcaacgt tggctagttt
    10381 gttgttaccg agatagtaga ggggagtgaa gaaaccagag tagaagagga aggtttcgag
    10441 gaagacgctg gcaactttct tttcaagtgg gctgccgttt aggtagattt cgttgacaat
    10501 ctcagccttc ttttgtaggt aaggattggt attggtccat tcgaaaattt cttcaatctc
    10561 agccttagta ttcaaggtag aaaagattga tgagtaagat ttagcgtgga cagattccat
    10621 aaattggatg ttattgaaaa cagcttcctc atgtggtgta cggatgtctg cgcgaagggc
    10681 ttgaacccca gtttcagatt gcatagtgtc aagaagggtt aaaccaccaa aaacttttcc
    10741 gaccaagtct ttctctttgt tagatagctt tctccagtca tccaagtcgt ttgataaggg
    10801 aatacgtgta tcgagccaaa attgctccgt cagtttttcc caagttgatt tgtcgatgac
    10861 atcttcgatg gcattccagt taatggcttt gtagtaagtt tccatttaaa atctctttct
    10921 gtgtttagta ttgcgaactc acaattattt ctactttacc ataattctat aggagtatcg
    10981 cacaaaaagt cggaagcccg acttttaaaa tgttacataa attatgttat gacatagtag
    11041 atttgatttt atcagtgctg cttagggaaa aataatgttt ctatgctaga aactaaatca
    11101 cacagctttc acattggttg gcgccgactt ctccaccgtc atctgtaaag gtacggacgt
    11161 agtagataga cttgattccc ttgttaaagg catagttacg aaggatggac aaatcacgtg
    11221 tcgtttgttt attttccctc ttccattcgt aaaggccttt tggaatgtca ctgcgcatga
    11281 agagggtgag tgaaagtcct tgatccacgt gttcagtcgc agcagcgtaa acatcgatga
    11341 ctttacgcat atccatatcg taggcagaag tgtagtaagg aatggtttct gtagacaagc
    11401 cagcagcagg gtagtagatt ttaccaattt tcttctcttg gcgttcttcg atacgttgcg
    11461 taatcgggtg gatagaagca gaaacgtcgt tgatatagct gatagaacca tttggcgcta
    11521 cagcaaggcg attttggtgg taaagaccat cttcttgaac cttgtcgcga agttcagccc
    11581 aatcagcaac accagggata aaaacatttt tgaagagttc tttaacacgg tctgatgttg
    11641 gaacaaattc accagttaca tacttgtcaa agtaacttcc gttagcatag tctgattttt
    11701 caaagttgtg gaaggtaata ccacgttcac gcgcaatatt gtttgactct accaaggtcc
    11761 agtagttcat aagcataaag tagatgcttg taaattcaac agactcaggt gaaccatatt
    11821 caatgagttg ttgggcaagg tagctgtgca gtcccatggc accgagacca aaggtgtggg
    11881 cttggctatt tccatggtca atcgttggta cagctacgat atgtgaacta tctgtaacga
    11941 aagtaagggc acgaaccata gcacggatag aacgaccaaa atcaggtgaa gtcatcatgt
    12001 taaccacgtt ggttgaaccc agattacatg aaacatctgt tcccatttga aggaattctt
    12061 gagcatcgtt gatcaagctt ggttcttgaa cttgaagaat ctcagaacac aagttactca
    12121 tgataatctt tccatcaaca ggatttgcac ggttagccgt atcgatgttg actacataag
    12181 gatagccaga ctcttgttgc aatttagaga tttcagtttc caaatcccgc gccttgattt
    12241 ttgtcttgcg aatatttgga tttgcgacca attcatcgta tttttcagta atgtcgatgt
    12301 aattgaatgg cacaccgtat tctttttcta cagagtaagg gctgaagagg tacatttctt
    12361 catttttacg agccaattcg tagaatttat caggtactac aacaccaagt gatagagtct
    12421 tgacacgtac tttttcatca gcgttttctt tcttagttga aaggaaagcg atgatatctg
    12481 ggtgaaagac gttgaggtag acaacaccag caccttgacg ttgccccaat tggttggagt
    12541 aagagaagct gtcttcaaaa agcttcataa caggaacgac acctgaagca gctccttcat
    12601 agcctttgat aggtgcacca gcttcacgaa ggttgctgag ggtaattccc acaccaccac
    12661 caatacgtga aagttgaaga gctgagttga tagaacgtcc gatagagttc atatcatccg
    12721 tcacttggat taggaaacaa gataccaact ccccacgacg agcacgtcca gcattcaaga
    12781 aggaaggagt agcaggttgg tagcgttggt ggatgatttc attggcaata tcgattgcaa
    12841 cagcttcatt cccatcagcg aaataaaggg cgttgaagaa gacacggtct tccatatttt
    12901 caagatagta ttcaccgtca ttagtcttta aggcatattg attgtaaaat ttataagctg
    12961 ccatgaatga cttgaattgg aagttttggt ctttgataaa ttgagccaat tcttccaaga
    13021 actctggacg gtatttcttg ataaaggctg tttcgatgta gttgtgttca atgaggtaat
    13081 tgattttgtc tttgattgaa tcaaaaacca tagtgtttgg aactacattt tctttaaaga
    13141 aagcatccaa ggcttcctta tctttatgaa gcatgatttg tccattaaca ggacggttaa
    13201 tttcgttatt aagacggaag taagtcacgt cttcaagatg ttttaatccc ataaaatttc
    13261 ccttatctaa ttacaaaaga aaggcttcta agttagccct aaaagcagtt tcttctggat
    13321 gatgtactaa gattatgcta attgtttcag ttttcctggt tggaaacctg aaaagacttc
    13381 agttggtgtt tggataacag gagctgcgct aaaaccgagc tctttaactt gatcgacgta
    13441 ctcaggttgc tcatcaagat tgatttcacg ataagagaca ttattactgt ccaagaaacg
    13501 cttggtcatt ttacattgga cacaattgtt tttagaataa acggttacca ttgtgtaact
    13561 cctcttcaaa atttaatact atcttagtat atcagaaaat aaaattttgt caatgatttg
    13621 aactaaatat agtggtgttc ttttgttgtt tttatatata aacacaatat atagtgtttg
    13681 tattgtgaaa tagcaatgat tatcctataa attgttttta aagaaactat atcctgtgtt
    13741 ttgttatcta ggatagaaga ttttcagcaa gttatctgaa aggaaattga aggaaaatcc
    13801 agaaaatgct tgaaaaaaat cctagaagat ggtataatac taaattgtaa gggttatcac
    13861 atataactca aaaaaagaaa gaacaaaagg agagtcaaac tatggcttct aaagatttcc
    13921 acgtagtggc agaaacaggt attcacgcac gtccagcaac attgttggta caaactgcta
    13981 gcaaatttgc ttcagatatc actcttgagt acaaaggtaa atcagttaac cttaaatcaa
    14041 ttatgggtgt tatgagtctt ggtgttggtc aaggtgctga cgtaactatc tcagctgaag
    14101 gtgcagatgc agatgacgct atcgctgcaa tctcagaaac aatggaaaaa gaaggattgg
    14161 cataagggaa atgacagaaa tgcttaaagg aatcgcagca tctgacggtg ttgcagttgc
    14221 aaaagcatat ctactcgttc agccggattt gtcatttgag actattacag tcgaagatac
    14281 aaacgcagaa gaagctcgcc ttgatgccgc tctacaggca tcacaagacg agctttctgt
    14341 tattcgcgag aaagcagtag gtacgctcgg tgaagaagca gctcaagttt ttgatgctca
    14401 cttaatggtt cttgctgacc cagaaatgat cagccaaatc aaggaaacta tccgtgcgaa
    14461 gaaagtgaat gcagaagcag gtctgaaaga agttacagat atgtttatca ctatctttga
    14521 aggcatggaa gacaacccat acatgcaaga acgcgcagcg gatatccgcg acgtgacaaa
    14581 acgtgtattg gcaaaccttc ttggtaaaaa attgccaaac ccagcttcta tcaatgaaga
    14641 agtgattgtg attgcgcatg acttgactcc ttcagataca gctcaattgg acaaaaactt
    14701 tgtaaaagct tttgtaacca acattggtgg acgtacaagc cactcagcta tcatggcacg
    14761 tacacttgaa attgctgctg tattaggtac aaacaacatc actgaaatcg ttaaagacgg
    14821 tgacatcctt gctgttaacg ggatcactgg agaagtgatt atcaacccaa cagatgaaca
    14881 agcggcagaa tttaaagcag ctggtgaagc ctatgcgaaa caaaaagctg aatgggcact
    14941 tttgaaagat gctcaaacag tgactgctga cggtaaacac ttcgagttgg ctgccaatat
    15001 tggtactcca aaagacgttg aaggtgttaa caacaacggt gcagaagctg ttggacttta
    15061 ccgtacagag ttcttgtaca tggattctca agacttccca actgaagatg agcagtatga
    15121 agcatacaag gctgttcttg aaggaatgaa cggtaaacct gttgtcgttc gtacaatgga
    15181 tatcggtgga gataaggaac ttccttactt cgatatgcct cacgaaatga acccattcct
    15241 tggattccgt gctcttcgta tctctatctc tgagactgga gatgctatgt tccgcacaca
    15301 aatccgtgct cttcttcgtg cgtctgttca cggtcaattg cgtatcatgt tcccaatggt
    15361 tgcgctcttg aaagaattcc gtgcagcgaa agcagtcttt gatgaagaaa aagcaaacct
    15421 tcttgctgaa ggtgttgcag ttgcggataa cattcaagtt ggtatcatga tcgagattcc
    15481 tgcagcggct atgcttgcag accaatttgc taaagaagtt gacttcttct caattggtac
    15541 aaatgacttg atccaatata caatggcagc agaccgtatg aacgaacaag tttcatacct
    15601 ttaccaacca tacaacccat caatcctacg cttgattaac aatgtgatca aagcagctca
    15661 cgctgaaggt aaatgggctg gtatgtgtgg tgagatggct ggtgaccaac aagctgttcc
    15721 acttcttgtc ggaatgggct tggatgagtt ctctatgtca gcaacatctg tacttcgtac
    15781 acgcagcttg atgaagaaac tcgacacagc taagatggaa gagtacgcaa accgtgccct
    15841 tacagaatgc tcaacaatgg aagaagttct tgaacttcaa aaagaatacg ttaattttga
    15901 ttaatcgaaa agtccctgca actcagttac agggactttt tttgatattt taaaaagaat
    15961 tttcaagaaa atctttctta taaaaagtcc aaccttgaaa aagtagtggt cagaacaaaa
    16021 aatacttaaa tggttcataa aattcttgac aagttggaga tttaggagta aactattaac
    16081 cagttaagta atagagagga gtttctgcaa tttagaaatg aattgcaact agaaatatca
    16141 aatagaaaga gagtttcgat gaaaattaat aagaaatacc ttgttggttc tgcggcagct
    16201 ttgattttaa gtgtttgttc ttacgagttg ggactgtatc aagctagaac ggttaaggaa
    16261 aataatcgtg tttcctatat agatggaaaa caagcgacgc aaaaaacgga gaatttgact
    16321 cctgatgagg ttagcaagcg tgaaggaatc aatgctgagc aaatcgtcat caagataaca
    16381 gaccaaggct atgtcacttc acatggcgac cactatcatt attacaatgg taaggttcct
    16441 tatgatgcga ttttcagtga agaattactc atgaaagatc caaactataa gctaaaagat
    16501 gaggatattg ttaatgaggt caagggtgga tatgttatca aggtagatgg aaaatactat
    16561 gtttacctta aggatgctgc ccacgcggat aacgtccgta caaaagagga aatcaatcga
    16621 caaaaacaag aacatagtca acatcgtgaa ggtgggactc caagaaacga tggtgctgtt
    16681 gccttggcac gttcgcaagg acgctatact acagatgatg gttatatctt taatgcttct
    16741 gatatcatag aggatactgg tgatgcttat atcgttcctc atggagatca ttaccattac
    16801 attcctaaga atgagttatc agctagcgag ttggctgctg ca
//
LOCUS       DAVBOD010000046        16835 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 640-05
            SAMEA1012484-rid20186543.denovo.046, whole genome shotgun sequence.
ACCESSION   DAVBOD010000046 DAVBOD010000000
VERSION     DAVBOD010000046.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012484
            Sequence Read Archive: ERR059358
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 16835)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16835)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979948.1
            Genome Coverage       :: 595x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:03:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,266
            CDSs (total)                      :: 2,219
            Genes (coding)                    :: 2,091
            CDSs (with protein)               :: 2,091
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 71 of 128
            Pseudo Genes (incomplete)         :: 50 of 128
            Pseudo Genes (internal stop)      :: 33 of 128
            Pseudo Genes (multiple problems)  :: 22 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16835
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012484-rid20186543.denovo.046"
                     /strain="NIG 640-05"
                     /db_xref="taxon:1313"
     gene            49..537
                     /locus_tag="VQ862_001589"
     CDS             49..537
                     /locus_tag="VQ862_001589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000747178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5590 domain-containing protein"
                     /protein_id="HET3115907.1"
                     /translation="MKKRQNKAKNNLLWQYGLGMTILFVVISASFLYMVSLSMKPYQT
                     AKSEGEKLAQQYAGLEQADQVDLYNGLESYYSVLGRNKQQEALAVLIGKDDHKIYVYQ
                     LNQGVSQEKAETVSKEKGAGEIDKIIFGRYQDKPIWEVKSGSDFYLVDFETGALVNKE
                     GL"
     gene            534..1721
                     /locus_tag="VQ862_001590"
     CDS             534..1721
                     /locus_tag="VQ862_001590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HET3115908.1"
                     /translation="MKLSNRVLEMEESVTLAAGARAKALKAEGRDILSLTLGEPDFTT
                     PKNIQDAAIASIRDGRASFYTVTSGLPELKAAVNSYFERFYGYSVASNQVTVAAGAKY
                     SLYTFFMAVVNPGDEVIIPTPYWVSYGDQVKMAEGVPVFVSTKEDNHFKVTVDQLEAA
                     RTDKTKVLVLNSPSNPTGMIYTREELLAIGNWAVENDILILADDIYGRLVYNGHEFTP
                     ISSLSEAIRKQTVVINGVSKTYAMTGWRIGYAVGEADIIAAMSKIAGQTTSNPSAVAQ
                     YAAVEALSGEQDTVESMRQAFEERLNTIYPLLAEVPGFEVVKPQGAFYLFPNVKKAME
                     MKGYTDVTDFTTAILEEAEVALVTGAGFGAPENVRLSYATDLDTLKEAVERLKAFMGS
                     END"
     gene            1714..2079
                     /locus_tag="VQ862_001591"
     CDS             1714..2079
                     /locus_tag="VQ862_001591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HET3115909.1"
                     /translation="MIDHFEIKVKDLQISEGFYRSFLAPLDYKMAFKTSSLISFLSPN
                     SPHPGGDFWLTQGTQDPVHFAFLAENKEEVQACYEAGLEAGGRDNGVPGYRSEHPIYY
                     AAFMIDLDGNNIEVVCHKE"
     gene            2095..3441
                     /gene="asnS"
                     /locus_tag="VQ862_001592"
     CDS             2095..3441
                     /gene="asnS"
                     /locus_tag="VQ862_001592"
                     /EC_number="6.1.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine--tRNA ligase"
                     /protein_id="HET3115910.1"
                     /translation="MMTKRVTIIDVKDYIGQEVTIGAWVANKSGKGKIAFLQLRDGTA
                     FFQGVAFKPNFVEKFGEEVGLEKFDVIKRLSQETSVYVTGIVKEDERSKFGYELDITD
                     IEVIGESQDYPITPKEHGTDFLMDNRHLWLRSRKQVAVLQIRNAIIYATYEFFDKNGF
                     MKFDSPILSGNAAEDSTELFETDYFGTPAYLSQSGQLYLEAGAMALGRVFDFGPVFRA
                     EKSKTRRHLTEFWMMDAEYSYLTHDESLDLQEAYVKALLQGVLDRAPQALETLERDTE
                     LLKRYIAEPFKRITYDQAIDLLQEHENDEDADYEHLEHGDDFGSPHETWISNHFGVPT
                     FVMNYPAAIKAFYMKPVPGNPERVLCADLLAPEGYGEIIGGSMREEDYDALVAKMDEL
                     GMDRTEYEFYLDLRKYGTVPHGGFGIGIERMVTFAAGTKHIREAIPFPRMLHRIKP"
     gene            3594..3884
                     /locus_tag="VQ862_001593"
     CDS             3594..3884
                     /locus_tag="VQ862_001593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018030687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S6"
                     /protein_id="HET3115911.1"
                     /translation="MAKYEILYIIRPNIEEEAKNALVARFDSILTDNGATVVESKTWE
                     KRRLAYEIQDFREGLYHIVNVEANDDAALKEFDRLSKINADILRHMIVKIDA"
     gene            3896..4366
                     /gene="ssbA"
                     /locus_tag="VQ862_001594"
     CDS             3896..4366
                     /gene="ssbA"
                     /locus_tag="VQ862_001594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003083754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein SsbA"
                     /protein_id="HET3115912.1"
                     /translation="MINNVVLVGRMTRDAELRYTPSNVAVATFTLAVNRTFKSQNGER
                     EADFINVVMWRQQAENLANWAKKGSLIGVTGRIQTRSYDNQQGQRVYVTEVVAENFQM
                     LESRSVREGHTGGAYSAPTANYSAPTNSVPDFSRNENPFGATNPLDISDDDLPF"
     gene            4398..4637
                     /locus_tag="VQ862_001595"
     CDS             4398..4637
                     /locus_tag="VQ862_001595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S18"
                     /protein_id="HET3115913.1"
                     /translation="MAQQRRGGFKRRKKVDYIAANKIEYVDYKDTELLSRFVSERGKI
                     LPRRVTGTSAKNQRKVTTAIKRARVMALMPFVNED"
     gene            4932..6332
                     /locus_tag="VQ862_001596"
     CDS             4932..6332
                     /locus_tag="VQ862_001596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional Cof-type HAD-IIB family
                     hydrolase/peptidylprolyl isomerase"
                     /protein_id="HET3115914.1"
                     /translation="MDAKLRYKAKKIKIVFFDIDDTLRNSKTGFIPTTIPTVFKQLRE
                     KGILTGIASGRGIFGVVPEIRDLKPDFFVTLNGAYIEDKKGQVIYQHQIEKSDVEEYI
                     SWAKQEGIEYGLVGSHDAKLSTRTDMMSEAINPIYPDLDVDPDFHEKEDIYQMWTFED
                     KGDDLHLPDSLSDKLRMVRWHQHSSDIVPISGSKATGVEKVVEHLGLKPEKVMVFGDG
                     LNDLELFDYAGISVAMGISHDKIKEKADYITKTLEEDGIFDALEVFGMVEKELHFPQV
                     DIETVEGLLATIKTNHGDLRIKLFPEHAPKTVANFVSLSKDGYYDGVIFHRIIKDFMI
                     QGGDPTGTGMGGESIYGESFEDEFSEELYNIRGALSMANAGPNTNGSQFFIVQNQHLP
                     YSKKEITRGGWPEPIAEIYANQGGTPHLDRRHTVFGQLADEASYAVLDAIAAVETGAM
                     DKPVEDVVIETIEIED"
     gene            6334..6693
                     /locus_tag="VQ862_001597"
     CDS             6334..6693
                     /locus_tag="VQ862_001597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000689596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S1 RNA-binding domain-containing protein"
                     /protein_id="HET3115915.1"
                     /translation="MKIGDKLKGRITGIQPYGAFVELETGDTGLIHISEIRTGFIENI
                     HETLKVDEEVQVQVVDLDEFTGKASLSIRTLEEEKYQFPRRRRFSSDRFNYGFAPFRR
                     MLPIWTGEALHHLKKKK"
     gene            6747..7496
                     /locus_tag="VQ862_001598"
     CDS             6747..7496
                     /locus_tag="VQ862_001598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000390787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA1(Val) (adenine(37)-N6)-methyltransferase"
                     /protein_id="HET3115916.1"
                     /translation="MEEEQLLKSGERINQLFSTDIKIIQNREVFSYSVDSVLLSRFPR
                     FPKKGLIVDFCAGNGAVGLFASTRTQAQILSVEIQERLADMAERSVRLNGLEEQMQVI
                     CDDLKNMPAHIQGSKVDMILCNPPYFKVDPYSNLNESEHYLLARHEITTNLEEICRSA
                     QSILKSNGRLAMVHRPDRLLDILDTLKRHNLAPKRLQFVYPKREKEANMLLIEAIKDG
                     STSGFKVLPPLIVHNDDGSYTPEIEEIYYGS"
     gene            7486..7785
                     /locus_tag="VQ862_001599"
     CDS             7486..7785
                     /locus_tag="VQ862_001599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HET3115917.1"
                     /translation="MDHKAYMYVLECRDGSYYIGYTTDVRRRLAIHNSGKGAKYTRAR
                     LPVKLIYAQGFASKEEAMSAEALLKRKKRPQKEEFLSENQDRNLLSYFEESWGVL"
     gene            7856..8791
                     /locus_tag="VQ862_001600"
     CDS             7856..8791
                     /locus_tag="VQ862_001600"
                     /EC_number="3.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000036024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese-dependent inorganic pyrophosphatase"
                     /protein_id="HET3115918.1"
                     /translation="MSKILVFGHQNPDSDAIGSSVAFAYLAKEAYGLDTEAVALGTPN
                     EETAFVLNYFGVEAPRVITSAKAEGAEQVILTDHNEFQQSVSDIAEVEVYGVVDHHRV
                     ANFETASPLYMRLEPVGSASSIVYRMFKEHGVAVPKEIAGLMLSGLISDTLLLKSPTT
                     HPTDKIIAPELAELAGVNLEEYGLAMLKAGTNLASKSAEELIDIDAKTFELNGNNVRV
                     AQVNTVDIAEVLERQAEIEAAMQAANESNGYSDFVLMITDIVNSNSEILALGANMDKV
                     EAAFNFKLENNHAFLAGAVSRKKQVVPQLTESFNA"
     gene            8877..9389
                     /locus_tag="VQ862_001601"
     CDS             8877..9389
                     /locus_tag="VQ862_001601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000892254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoylalanyl-D-glutamate--2,
                     6-diaminopimelate ligase"
                     /protein_id="HET3115919.1"
                     /translation="MLENGDLIFVRDGSDMGQAIQTSTGNYSHVAIYLDGMIYHASGQ
                     AGVVCQEPADFFESNHLYDLYVYPEMDIQSVKERACRHLGAPYNASFYPDAAGFYCSQ
                     YIAEILPIFETIPMKFGDGEQEISDFWREYYIELGLPVPLNQAGTNPSQLAASPLLQC
                     KERNLHDSDF"
     gene            9426..10021
                     /locus_tag="VQ862_001602"
                     /pseudo
     CDS             9426..10021
                     /locus_tag="VQ862_001602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809149.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1803 domain-containing protein"
     gene            10122..10316
                     /locus_tag="VQ862_001603"
     CDS             10122..10316
                     /locus_tag="VQ862_001603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000051203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HET3115920.1"
                     /translation="MSLENKLEQATGAVKEGFGKVTGDSKTELEGAVEKTVAKAKDVV
                     EDAKGAVEGAVEGLKNVFTK"
     gene            complement(10362..11807)
                     /locus_tag="VQ862_001604"
     CDS             complement(10362..11807)
                     /locus_tag="VQ862_001604"
                     /EC_number="6.3.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-
                     lysine ligase"
                     /protein_id="HET3115921.1"
                     /translation="MIKIETVLDILKKDGLFREIIDQGHYHYNYSKVIFDSISYDSRK
                     VTEDTLFFAKGAAFKKEYLLSAITQGLAWYVAEKDYEVDIPVIIVNDIKKAMSLIAME
                     FYGNPQEKLKLLAFTGTKGKTTATYFAYNILSQGHRPAMLSTMNTTLDGETFFKSALT
                     TPESIDLFDMMNQAVQNDRTHLIMEVSSQAYLVHRVYGLTFDVGVFLNITPDHIGPIE
                     HSSFEDYFYHKRLLMENSRAVIINSDMDHFSVLKEQVEDQDHDFYGSQFDNQIENSKA
                     FSFSATGKLAGDYDIQLIGNFNQENAVAAGLACLRLGASLEDIKKGIAATRVPGRMEV
                     LTQKNGAKVFIDYAHNGDSLKKLINVVETHQTGKIALVLGSTGNKGESRRKDFGLLLN
                     QHPEIQVFLTADDPNYEDPMAIADEISSYINHPVEKIADRQEAIKAAMAITNHELDAV
                     IIAGKGADCYQIIQGKKESYPGDTAVAENYL"
     gene            11913..13535
                     /locus_tag="VQ862_001605"
     CDS             11913..13535
                     /locus_tag="VQ862_001605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HET3115922.1"
                     /translation="MSHENNHQQAQMLRGTAWLTASNFISRLLGAVYIIPWYIWMGAY
                     AAKANGLFTMGYNIYAWFLLVSTAGIPVAVAKQVAKYNTMREEEHSFALIRSFLGFMT
                     GLGLVFALVLYVFAPWLADLSGVGKDLIPIMQSLAWGVLIFPSMSVIRGFFQGMNNLK
                     PYAMSQIAEQVIRVIWMLLATFIIMKLGSGDYLAAVTQSTFAAFVGMVASFAVLIYFL
                     AQEGSLKRVFETGDKINSKRLLVDTIKEAIPFILTGSAIQLFQILDQLTFINSMSWFT
                     NYSNEDLVVMFSYFSANPNKITMILISVGVSIGSVGLPLLTENYVKGDLKAASRLVQD
                     SLTLLFMFLLPATVGVVMVGEPLYTVFYGKPDSLALVLFVFAVLQSIILGLYMVLSPM
                     LQAMFRNRKAVLYFIYGSIAKLVLQLPTIALFHSYGPLISTTIALIIPNVLMYRDICK
                     VTGVKRKVILKRTILISLLTLVMFLLIGTIQWLLGFFFQPSGRLWSFFYVALVGAMGG
                     GLYMVMSLRTYLLDKVIGKAQADRLRAKFKLS"
     gene            13738..15696
                     /locus_tag="VQ862_001606"
     CDS             13738..15696
                     /locus_tag="VQ862_001606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000748873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HET3115923.1"
                     /translation="MKKSKSKYLTLAGLVLGTGVLLSACGNSSTASKTYNYVYSSDPS
                     SLNYLAENRAATSDIVANLVDGLLENDQYGNIIPSLAEDWTVSQDGLTYTYKLRKDAK
                     WFTSEGEEYAPVTAQDFVTGLQYAADKKSEALYLVQDSVAGLDDYITGKTSDFSTVGV
                     KALDDQTVQYTLVKPELYWNSKTLATILFPVNADFLKSKGDDFGKADPSSILYNGPFL
                     MKALVSKSAIEYKKNPNYWDAKNVFVDDVKLTYYDGSDQESLERNFTAGAYTTARLFP
                     NSSSYEGIKEKYKNNIIYSMQNSTSYFFNFNLDRKSYNYTSKTSDIEKKSTQEAVLNK
                     NFRQAINFAFDRTSYGAQSEGKEGATKILRNLVVPPNFVSIKGKDFGEVVVSKMVNYG
                     KEWQGINFADGQDPYYNPEKAKAKFAEAKKELEAKGVQFPIHLDKTVEVTDKVGIQGV
                     SSIKQSIESVLGSDNVVIDIQQLTSDEFDSSGYFAQTAAQKDYDLYHGGWGPDYQDPS
                     TYLDIFNTNSGGVLQNLGLEPGEANDKAKEVGLDVYTQMLEEANKEQDPAKRYEKYAD
                     IQAWLIDSSLVLPSVSRGGTPSLRRTVPFAAAYGLTGTKGIESYKYLKVQDKIVTTDE
                     YAKAREKWLKEKEESNKKAQEELAKHVK"
     gene            15868..16428
                     /locus_tag="VQ862_001607"
     CDS             15868..16428
                     /locus_tag="VQ862_001607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000768990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3115924.1"
                     /translation="MKLKLLRVDTKVIMGSFLLVLSSLLALLLPLILKGLIDGSSIEN
                     IGSKVFQSFLIFIGQALFSSIGYYLFSQSGEKKIAKIRKKVIEGLIYAEKSFFDKSQS
                     GELTSAIVNDTSVIREFLITTFPNIILSLVMVLGSIVVLFSLDWNLSLLLFITLPCMM
                     FIILLLSNISEKYSRRLQEEIGFLTG"
     gene            16429..16803
                     /locus_tag="VQ862_001608"
     CDS             16429..16803
                     /locus_tag="VQ862_001608"
                     /inference="COORDINATES: protein motif:HMM:NF012869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3115925.1"
                     /translation="MTEKIQEHELIKTNQAEKSVQDVLDNCIERVQNNSLKSDRVTSF
                     ETPFALLFIFATIAVMLTYGGYRVSAGYISVGTLVSFLIYLFQLLNPISNIANFVTVY
                     SRSKGSSVALENLLAVPKEKFE"
BASE COUNT         4991 a         3092 c         3753 g         4999 t
ORIGIN      
        1 ttcttatatt cacttgtaat aaagcttaat agatggtaaa atagacgagt gaaaaaaaga
       61 caaaacaaag caaaaaataa tctactgtgg cagtatggtc tagggatgac gattttgttt
      121 gtggttatca gtgcttcctt tctgtatatg gtttctctta gcatgaaacc ctatcaaaca
      181 gctaaaagtg aaggagaaaa attagctcag cagtatgcag gattagagca ggccgatcag
      241 gttgatttat acaatggctt ggaatcttat tacagcgttc ttggtcgtaa taaacagcaa
      301 gaagcacttg ctgttctgat tggaaaagat gatcataaga tttacgttta tcagctaaat
      361 cagggtgttt cacaagaaaa agcagaaacg gtttctaagg aaaagggagc tggcgaaatt
      421 gacaagatta tctttggtcg ttatcaagat aagccaatct gggaagtcaa gtcaggatct
      481 gatttttatc tagtagattt tgaaacagga gcattggtca acaaggaggg cctatgaaat
      541 tatccaaccg tgttttagaa atggaagaaa gtgtgacttt ggctgctgga gcccgtgcca
      601 aagcactgaa ggctgagggc agagatattt tgtctctaac cttgggtgag ccagatttca
      661 ctactcccaa aaatatccaa gatgccgcca ttgcatcgat tcgagatggg cgtgcttctt
      721 tttatacagt aacctcaggt ctgccagagc ttaaggcggc ggtcaatagc tactttgagc
      781 gcttttacgg ctattctgta gcgtcaaatc aagtgacagt cgctgcggga gccaaatatt
      841 ctctctatac cttctttatg gctgtggtca atccaggtga tgaagtcatc atcccaaccc
      901 catactgggt tagctatgga gatcaggtca agatggcaga aggcgttccc gtctttgttt
      961 ctactaagga agacaatcac tttaaggtga ccgtagatca gttagaagca gctcgcactg
     1021 acaagaccaa ggttttggtg ctgaattcgc catctaatcc cacaggtatg atttacaccc
     1081 gtgaggaact cttggcaatt ggaaactggg ctgtagaaaa tgatattctc atcctagcag
     1141 atgatatcta tggccgcttg gtttataatg gtcatgagtt cacaccgatt tctagcctat
     1201 cggaagcgat tcgcaagcaa acagtggtca tcaatggtgt gtctaaaacc tatgccatga
     1261 ctggttggcg gattggttat gccgttggag aagcagacat tatcgctgcc atgtccaaga
     1321 ttgcaggtca aacaacttcg aatccgtcag cagtagccca atatgcagca gttgaggctc
     1381 tatcaggtga gcaagatact gtagaaagca tgcgtcaggc ctttgaggaa cgtcttaata
     1441 ctatctatcc cctccttgca gaggtgccag gatttgaagt ggtcaaaccg caaggggcct
     1501 tctatctctt cccaaatgtc aaaaaggcca tggagatgaa aggctacacg gatgtgacag
     1561 actttacaac tgctatctta gaagaagccg aagtggcctt ggtaacagga gctggatttg
     1621 gagcaccaga aaatgtccgc ctcagctatg cgacagacct agacacgctt aaagaagcag
     1681 tcgaacgctt gaaagcattt atgggtagtg agaatgattg atcattttga gattaaggta
     1741 aaggatttac aaatttcaga aggattttat aggagttttc tcgctccttt ggactataaa
     1801 atggctttta agactagttc tctaattagt tttctatccc cgaacagccc tcatcctggt
     1861 ggtgattttt ggctgactca gggaacacaa gatcctgttc attttgcttt tttagcagaa
     1921 aataaggaag aagttcaggc ttgttatgag gctggcttag aggcaggtgg gcgagacaat
     1981 ggggttcctg gttatcgaag tgagcatccg atttattatg ctgcttttat gattgacctg
     2041 gatgggaaca atatagaggt ggtttgccat aaagaataaa aaagaaaagg aaaaataatg
     2101 acaaaacgtg taacgattat tgatgtaaaa gactatattg gtcaagaagt gacgattggc
     2161 gcttgggttg ccaacaaatc aggaaaaggg aaaatcgctt tcttacaatt gcgtgatgga
     2221 acagccttct ttcaaggtgt ggcttttaaa ccaaactttg tcgaaaaatt tggtgaagaa
     2281 gtgggacttg agaagtttga tgttatcaaa cgcttgagcc aagaaacgtc tgtttatgtg
     2341 acaggtattg tcaaagagga cgaacgttct aaatttggct atgagttgga catcacagac
     2401 atcgaagtga tcggtgaatc tcaagactac ccaatcacac caaaagaaca cggaacagac
     2461 tttttgatgg ataaccgtca cttgtggcta cgctctcgta agcaagtagc tgtgttgcaa
     2521 atccgtaacg ctattatcta tgcaacttat gagttctttg acaagaacgg ttttatgaag
     2581 tttgacagcc caattctttc aggaaatgcg gcagaagatt ctacagaact ctttgaaact
     2641 gactacttcg gaacgccagc ctacttgagc caatcaggtc aactttacct agaagcaggg
     2701 gctatggctc ttggtcgtgt ctttgacttt ggtccagttt tccgtgctga aaaatcaaaa
     2761 acacgccgtc acttgactga gttctggatg atggatgctg agtactcata cttgacacat
     2821 gatgagtcgc ttgacttgca agaagcttat gtgaaagctc ttctacaagg tgttcttgac
     2881 cgcgcgcctc aagccttgga aaccttggaa cgtgatacag aactcttgaa acgctacatt
     2941 gcagagccat tcaaacgtat cacttacgat caagccattg acctcttgca agagcatgaa
     3001 aatgatgaag atgctgacta cgagcatctt gagcatggtg atgactttgg gtcaccacac
     3061 gaaacttgga tttcaaacca ctttggtgtg ccaacatttg tcatgaacta tccagcagcc
     3121 atcaaggctt tctacatgaa accagttcct ggaaatccag agcgcgtgct ttgtgcagac
     3181 ttgcttgctc cagaaggcta tggagaaatt atcggtgggt ctatgcgtga ggaagattac
     3241 gatgcccttg tcgctaagat ggatgaactt ggcatggatc gtacagaata tgaattctac
     3301 cttgaccttc gtaaatacgg tacagttcca cacggaggat ttggtatcgg tatcgaacgt
     3361 atggtaacct tcgcagcagg aacaaaacat atccgtgaag ctattccatt cccacgtatg
     3421 ttgcaccgta tcaaaccata agaacaggaa aacgcccatg tggcgttttt tcgaattcta
     3481 gtgtttttac ttgcgtaaaa aaattttttc tagtataata gtttattgtg agcgaacctc
     3541 acttacccct tgcaaagtct tggggtcatt agaccaaaag gaggaacata tcaatggcta
     3601 aatacgaaat tctttatatc attcgtccaa acattgaaga agaagctaaa aacgctttgg
     3661 tagcacgttt tgactctatt ttgactgaca acggtgcaac tgttgttgaa tcaaaaactt
     3721 gggaaaaacg tcgtcttgca tacgaaatcc aagatttccg tgaaggactt taccacatcg
     3781 ttaacgttga agcaaatgac gatgcagctc ttaaagagtt tgaccgtctt tcaaaaatca
     3841 acgctgacat tcttcgtcac atgatcgtca aaattgacgc gtaagaaggt aaactatgat
     3901 taacaatgtt gtacttgtag ggcgtatgac acgtgacgct gagttgcgtt ataccccatc
     3961 aaatgtagca gttgcgactt ttactcttgc agtaaaccgt acatttaaga gtcaaaatgg
     4021 tgaacgtgag gctgatttta tcaatgtcgt tatgtggcgc caacaggctg aaaatcttgc
     4081 taactgggct aaaaaaggct cacttatcgg ggtgacaggt cgtatccaga ctcgtagtta
     4141 cgataaccag caaggacaac gtgtctacgt gacagaggtc gtggctgaga atttccaaat
     4201 gttggaaagc cgtagtgtgc gtgagggtca cacaggtgga gcttactctg caccaactgc
     4261 aaactattca gcacctacaa attcagtacc agacttttca cgtaatgaaa atccatttgg
     4321 agcaacaaac ccattggata tttcagatga tgatttacca ttctaatgga caactaaact
     4381 tataaaggag aaaaaacatg gctcaacaac gtcgtggcgg attcaaacgc cgtaaaaaag
     4441 ttgattacat cgcagcaaac aaaattgaat atgttgatta caaagatact gagcttctta
     4501 gccgtttcgt ttcagaacgt gggaaaatcc ttcctcgtcg tgtaacagga acttcagcta
     4561 aaaaccaacg taaagtaaca acagctatca aacgcgctcg cgtaatggct ttgatgcctt
     4621 tcgtaaacga agattaaaga aaagacccgg ttgggtctct ttttcatgag cttgaaaaca
     4681 agaaagcgaa ttaagacccc aacgggtctt ttttcacaag ctttgaaatg agagagcgag
     4741 ttaggctcag tggcttcctt tttacgagtt tgaaaacaag agaacacatt aaaagcacga
     4801 tggagctttt tcataaatat gtctcttttc tcatccaaga aattaaaata aaaatgataa
     4861 actttttgaa aataggggat ttgcctactt tatgatataa tggaaagagt tagattgaaa
     4921 gaggtagtga gatggacgcg aaattaagat acaaggcaaa gaagatcaag attgtctttt
     4981 ttgatattga tgatacattg cggaattcaa agacagggtt tattccaact acaattccca
     5041 ctgtttttaa acagttgcgt gaaaaaggaa ttttaacagg aatcgcctct ggacgtggca
     5101 tttttggtgt tgttccagag attcgtgatc tcaagcctga cttttttgta actttgaatg
     5161 gggcttatat cgaagataaa aaaggtcagg tcatttatca gcatcagatt gaaaagtcag
     5221 atgttgagga gtatatctct tgggctaagc aagaaggaat tgagtatggc ttggttggga
     5281 gtcatgatgc caagttgtcg actcgcaccg atatgatgag tgaagctatc aatccaattt
     5341 atcccgactt agatgtagat cccgatttcc atgaaaaaga agatatctat cagatgtgga
     5401 cttttgaaga taagggagat gacttgcact tgcctgacag tctctcagac aaacttcgca
     5461 tggttcgttg gcatcaacat tcgtctgata ttgtgccgat ttcaggctcc aaagcgacgg
     5521 gggtggaaaa ggttgtggaa caccttggct tgaaaccaga gaaggtcatg gtttttggag
     5581 atggtctcaa tgacttggaa ctctttgatt atgctggaat cagcgttgcc atgggaattt
     5641 ctcatgataa aatcaaagaa aaagcagatt atattacaaa aacattagaa gaagatggca
     5701 tttttgatgc cttagaagta tttggtatgg tagaaaaaga attgcatttt ccacaagtag
     5761 acattgaaac agtagaaggt cttcttgcga ctattaagac caatcacgga gacttacgta
     5821 tcaagctttt ccctgaacat gctcctaaaa cagtggctaa ctttgtatct ctttcaaaag
     5881 atggctacta tgatggtgtc attttccacc gtattatcaa ggactttatg atccaaggtg
     5941 gagacccaac tggaactggt atgggtggcg agtcaatcta cggcgaatct tttgaggatg
     6001 aattctcaga agagctttac aatatccgtg gtgctctttc catggcaaat gctggtccaa
     6061 ataccaacgg cagccagttc tttatcgtgc aaaaccaaca cctaccttat tcgaagaaag
     6121 aaattactcg tggtggttgg ccagaaccga ttgcagaaat ctatgccaat caaggtggga
     6181 cacctcacct agaccgccgt cacacggttt ttggtcagtt agctgatgaa gcatcttacg
     6241 ctgtcttgga tgccattgct gctgttgaga caggagctat ggacaagcca gttgaagatg
     6301 ttgtaattga aactattgaa atcgaggact aagatgaaaa tcggtgataa gctaaagggg
     6361 cgtattacag ggattcagcc ctacggtgcc tttgttgagt tagagacggg tgatacgggg
     6421 ctgattcaca tttcagaaat tcggacagga tttattgaaa atattcatga aaccttgaaa
     6481 gtcgatgaag aggttcaagt tcaggtagtg gatttagatg aatttacggg gaaagccagt
     6541 ctttctatcc gcactttgga ggaagaaaag taccagtttc ctagacggag acgcttttca
     6601 agtgaccgct ttaactacgg ttttgctccc tttcgacgaa tgctaccaat ctggactgga
     6661 gaagctctgc accatttaaa aaagaagaag tagtttagag ttttatattt tttgtaatgt
     6721 taatataaat ttattataat aggaccatgg aagaagaaca attattaaaa tcaggagagc
     6781 gcattaacca gctcttttcg acagatatca aaatcattca aaatagagag gtttttagct
     6841 attcggtgga tagtgttctc ttatcacgat ttccacgttt tcctaagaag gggttgattg
     6901 tggatttctg tgctgggaat ggagcagtgg ggctttttgc tagcactcgt actcaagcac
     6961 agatattgtc tgttgagatt caggagcgtt tggcggatat ggctgaacgc tctgtccgtt
     7021 tgaatggatt agaggagcaa atgcaggtca tctgcgatga tttgaaaaat atgcctgctc
     7081 acattcaggg gagtaaggta gatatgattt tgtgtaatcc accctatttc aaggtggatc
     7141 cttattctaa tctgaacgag agtgaacatt atctcttggc tcgacacgaa atcacgacta
     7201 atttggaaga aatctgtcgt agtgcccaga gtattctcaa gtctaatggg cgtttggcca
     7261 tggttcatcg tcctgatcga cttctggata ttttggatac gttaaaacga cataatctag
     7321 cccctaagcg cctgcagttt gtttatccaa aaagagaaaa ggaagccaat atgcttttga
     7381 ttgaggcgat caaggatggc tcaacaagtg gctttaaggt cttacctcct ttgattgtcc
     7441 acaatgatga tggctcttat acgcccgaaa tcgaagagat ttattatgga tcataaggct
     7501 tatatgtacg ttctggagtg tcgtgatgga tcctactata taggctatac gactgatgtg
     7561 agaagacgcc tcgctatcca caatagtggg aagggagcca aatatacacg agcacgcttg
     7621 ccagtcaaac ttatctatgc tcaaggtttt gccagtaagg aagaagccat gtcggctgaa
     7681 gctcttctca agcgtaagaa gaggccacag aaggaagaat ttttatctga aaatcaagat
     7741 agaaatttac tcagttattt tgaagaatcg tggggagtcc tttgactcct cttacctttg
     7801 tcaaaaagcg aaaaaaatgc tacaataaag aaaataaaca aaatgaggta ttatcatgtc
     7861 caagattcta gtatttggtc accaaaatcc agactcagat gccatcgggt catctgtagc
     7921 ttttgcctac cttgcaaaag aagcttacgg tttggatacg gaagctgttg cccttggaac
     7981 tccaaatgaa gaaacagcct ttgtcttgaa ctattttggt gtggaagcac cacgtgttat
     8041 cacttctgcc aaagcagagg gggcagagca agttatcttg actgaccaca atgaattcca
     8101 acaatctgta tcagatatcg ctgaagtaga agtttacggt gttgtagacc accaccgtgt
     8161 ggctaacttt gaaactgcaa gcccacttta catgcgtttg gagccagttg gatcagcgtc
     8221 ttcaatcgtt taccgtatgt tcaaagaaca tggtgtagct gtgcctaaag agattgcagg
     8281 tttgatgctt tcaggtttga tttcagatac ccttcttttg aaatcaccaa caacacaccc
     8341 aacagataaa atcattgctc ctgaattggc tgaattggct ggtgtgaact tggaagaata
     8401 tggtttggca atgttgaaag ctggtaccaa cttggctagc aaatctgctg aagaattgat
     8461 tgatatcgat gctaagactt ttgaactcaa cggaaataat gtccgtgttg cccaagtgaa
     8521 cacagttgac atcgctgaag ttttggaacg ccaagcagaa attgaagctg caatgcaagc
     8581 tgcaaacgaa tcaaacggct actctgactt tgtcttgatg attacagata tcgtcaactc
     8641 aaactcagaa atcttggctc ttggtgccaa tatggacaag gtcgaagcgg ctttcaactt
     8701 caaacttgaa aacaatcatg ccttccttgc tggtgccgtt tcacgtaaga aacaagtggt
     8761 acctcaattg actgaaagct ttaatgcgta agattttggg tgtcagctca aaatcggaaa
     8821 gtctagtttg ccttatatcg aaaggagttt cggctccttt tttctaggag tgaagtatgt
     8881 tagaaaatgg cgatttgatt tttgtgagag atgggtcaga catgggacag gccatccaga
     8941 cttccacagg taactatagc catgttgcca tttatttgga tgggatgatt tatcatgcta
     9001 gtggacaggc tggtgttgtc tgtcaagaac cggcagactt ctttgagtcc aatcatttgt
     9061 acgacctcta tgtttaccca gaaatggata tccagtcggt gaaggaaaga gcttgcagac
     9121 atcttggagc accctacaat gcttctttct atccagatgc agctggtttc tactgctccc
     9181 agtatatagc agaaatccta cctatttttg aaactattcc tatgaaattt ggagatgggg
     9241 aacaggagat tagtgatttt tggagggagt attacataga actaggtctg cctgttcctc
     9301 tgaaccaagc tgggaccaat cctagtcagt tggcagcatc gcctctgtta caatgtaaag
     9361 aaaggaatct tcatgattca gatttttaat ccatctcgtt tgacgagaca gccatttttg
     9421 gagaattgat ccgctatctg gaccagtatg aggatgtgat tctacgggaa attaaggctc
     9481 aatttccaga tgttgcagtt gataaactca tggaagagta tataaaggca agcttgattc
     9541 tacgtgaaaa taagcgctat tacctcaatt ttcctacgct tgaatcactt gatagtcttg
     9601 aactggatca agagattttt gtcagagaag ctagtccggt ctatcaagcc ttgttggagc
     9661 agagttttga gacggaattg cgcaatcaaa tcaatgcagc tattttagtt gaaagacgga
     9721 ctttgcgcgc attaaaatga ccctgtccaa ttatttttac aaggtcaaac agcagtatcc
     9781 tttgacagaa aaacagcagg agctctatga cattttagga gatgttaatc ctgagtatgc
     9841 actcaagtat atgacggctt ttttgttgaa atttctcaaa aaagaccagc ttatgcagaa
     9901 atgccgtgat atctttgtgg acagtttggt tgtcttaggc tatattgtgc aaaatgaaga
     9961 tagaaagtat gagttggcta tcgattttga taaggagaga ttaactttct acttagcgtg
    10021 atttcttgtt tctgagcaca ttgtttgact ttccttagta ttcggtataa actatatgta
    10081 accggtaaca catatcggaa taaactaaag gagacaatca tatgtcactt gaaaacaaat
    10141 tggaacaagc aacaggcgct gtcaaagaag gttttggtaa agttactgga gacagcaaga
    10201 cagaacttga aggagctgtt gaaaaaacag ttgctaaggc aaaagacgtt gtagaagacg
    10261 caaaaggtgc tgtagaaggt gccgttgaag gtttgaaaaa cgtttttact aaataatagg
    10321 aaaaaatcaa gggtttcatt ttcccttgat tttttctatt cttataaata attttctgcg
    10381 acggctgtat ctcctgggta ggattctttc ttgccctgga tgatttggta acaatcggct
    10441 cccttacccg caataataac tgcatctaat tcgtgatttg tgatagccat tgccgccttg
    10501 atggcttctt ggcgatccgc aatcttttca acaggatgat tgatgtagct actaatttca
    10561 tctgcaatgg ccattgggtc ttcatagtta gggtcatcag cagtcagaaa gacttgaatc
    10621 tcagggtgtt gattgaggag gaggccaaag tccttacgac gactttctcc cttgtttcct
    10681 gttgatccca gaaccagagc aatctttccg gtttgatgag tttcaaccac attgatgagt
    10741 tttttcagac tatccccatt gtgggcatag tcgatgaaga ccttggctcc atttttctga
    10801 gtgaggactt ccatacgacc aggaacgcgg gttgcagcga tgcctttttt gatgtcctca
    10861 agacttgctc cgagacggag acaagcaagt ccagcagcaa ctgcattttc ttggttgaag
    10921 ttgccaatga gttggatatc ataatctcca gcgagtttac ccgtagctga aaagctaaag
    10981 gctttggaat tctcgatttg gttatcaaat tggctaccat agaaatcatg gtcttgatct
    11041 tcaacctgtt ctttcaagac tgagaagtgg tccatgtcac tgttaatgat gactgctcgg
    11101 ctattttcca tcaagagacg cttgtggtag aaatagtctt caaagctaga gtgttcaatc
    11161 gggccgatat ggtcaggagt gatgttaaga aagactccta catcaaaggt cagtccatag
    11221 actcgatgga ctagataggc ttgactggag acttccatga tgaggtgggt acggtcattt
    11281 tgcacagcct gattcatcat gtcaaagagg tcaatactct caggggttgt caacgctgac
    11341 ttaaaaaaag tctcgccatc aagagttgtg ttcatggtcg acaacatagc aggtctatgc
    11401 ccttgagata agatgttata ggcgaaatag gttgctgttg tcttaccctt agtaccagta
    11461 aaggcaagga gtttgagttt ctcttgtgga ttaccataga actccatggc aatcaaactc
    11521 atggctttct ttatatcgtt cacaatgatg acagggatat cgacttcgta gtccttttca
    11581 gctacatacc aagctaaacc ttgtgttata gcagaaagaa ggtattcttt tttaaaggca
    11641 gcgccttttg caaaaaaaag agtgtcttct gttacttttc ggctgtcgta gctgatgcta
    11701 tcaaaaataa ctttgctgta gttgtagtgg taatgacctt ggtcaataat ttcgcgaaaa
    11761 aggccatctt tctttaaaat atctaatacg gtttcaatct taatcatact ttctattgta
    11821 aaccgaaagt cgtaaattta caagtaacaa ggaaaagttt ataatggaag ataaggagtt
    11881 tttcctagtt atcaaaattg aatgaggaat ctatgtcgca cgaaaacaat caccagcagg
    11941 cccagatgtt acgggggact gcttggctaa cggctagtaa ctttatcagt cgcctactcg
    12001 gggctgttta cattatccct tggtacatct ggatgggggc ttatgcagct aaggcaaatg
    12061 gtctctttac catgggttac aatatctatg cttggttctt gttggtttca acagcgggga
    12121 ttccagttgc ggtggccaag caagttgcca agtataatac catgcgagaa gaagagcata
    12181 gctttgccct gattcggagc ttcttaggct ttatgacagg actaggtctg gtttttgctt
    12241 tagtcttgta tgtctttgct ccttggctag cagacttgtc tggcgtgggc aaagacttga
    12301 tcccaatcat gcaaagcttg gcttggggag tcttgatttt cccgtctatg agtgttatcc
    12361 gaggattttt ccaagggatg aataacctca aaccctatgc tatgagccaa attgctgagc
    12421 aggtcattcg tgttatctgg atgctcctag caacctttat cattatgaag ctcggttcag
    12481 gagattatct agcagccgtt acccaatcaa cctttgctgc ctttgtcggt atggtagcca
    12541 gttttgcagt cttgatttat ttccttgccc aagaaggttc actcaaaaga gtctttgaaa
    12601 caggagataa gattaacagt aagcgtctct tggttgatac cattaaggaa gccattcctt
    12661 ttatcctgac agggtctgcc atccagctct tccagatttt ggatcagctg acctttatca
    12721 atagtatgag ctggtttacc aactacagca atgaggactt ggttgtcatg ttttcttatt
    12781 tctcagccaa tcctaataaa atcacgatga ttttgatttc tgtaggggtt tcgattggga
    12841 gtgttggttt gccacttttg acggaaaact atgtcaaggg ggacttgaaa gcagcttctc
    12901 gtctcgttca ggacagtctc accctactct ttatgttctt gctaccagca acggttggag
    12961 tggttatggt aggagaacct ctttatacgg tcttctatgg taagccagat agtttggctc
    13021 tggtcttatt tgtctttgca gttttgcagt ctattatttt aggcttgtac atggtcttgt
    13081 ctccaatgct tcaggccatg ttccgcaacc gcaaggccgt tctctatttt atctatggtt
    13141 ctattgccaa gctagtcttg caactaccta ccatcgccct cttccacagt tatggtcctt
    13201 tgatttcaac aaccattgct ctcatcattc ctaacgtctt gatgtatcgg gatatttgta
    13261 aagtaactgg tgtcaagcgc aaggtgattt tgaagcgaac cattttaatc agtttgctga
    13321 ccctagtcat gtttctgtta ataggaacca tccagtggct gttaggattt ttcttccaac
    13381 caagtggacg tttgtggagc ttcttttatg tagctcttgt cggtgccatg gggggtggac
    13441 tttatatggt tatgagtctg cgtacctatt tattagataa ggtaatagga aaagcccaag
    13501 cagatcgcct gcgagcaaaa tttaagcttt cgtaaggtag catttataaa taaaaggaat
    13561 aagttgaaca atcttttagg agaacttgaa acttattcct tttttagcgt caaaatagct
    13621 aaaattatct ttcaaaaata gaaaatgagg tttttttgat tttttggaaa aaacaattga
    13681 ctaaacaaac ccagagttgt ataataaaac aaatatttaa agcaggaggt tctggaaatg
    13741 aaaaagtcta agagcaaata tctaaccttg gcaggtcttg tcctgggtac aggagtttta
    13801 ttgagcgcgt gtggaaattc tagcactgca tcaaaaacct ataactatgt ttattcaagt
    13861 gatccatcta gtttgaacta tctagcagaa aaccgcgcag caacatccga tattgttgca
    13921 aatttggtag acgggttatt agaaaatgac caatatggga atattattcc atcattagca
    13981 gaggattgga ctgtttctca ggacggtttg acctatacct acaaacttcg taaggatgcc
    14041 aagtggttta cttctgaggg agaagaatat gcgcctgtaa ctgcccagga ttttgtgaca
    14101 ggtttgcaat atgcagctga taaaaaatca gaagctttgt atctagtgca ggactctgtt
    14161 gctggtttgg atgactatat cactggtaaa acaagcgact tttcaactgt cggtgtcaag
    14221 gcacttgatg accaaacggt tcaatatact ttggttaaac cagaacttta ctggaattca
    14281 aaaacacttg caacgatact ttttcctgtt aatgcagatt tcctgaaatc aaaaggggat
    14341 gattttggga aggcggatcc atctagtatt ttgtacaatg gacctttctt gatgaaagca
    14401 cttgtctcaa aatctgctat tgaatataag aaaaacccta attactggga tgctaagaat
    14461 gtctttgtag acgatgtgaa attgacctac tatgatggta gcgaccaaga atcactggaa
    14521 cgtaatttta cagctggtgc ttatactacg gctcgtcttt ttcctaacag ctccagctat
    14581 gaagggatta aagaaaaata caaaaacaat atcatatata gtatgcaaaa ttcaacttca
    14641 tatttcttta attttaacct agataggaag tcttacaatt atacttctaa aacaagtgac
    14701 attgaaaaga aatcgactca ggaagcagtt ctcaataaaa acttccgtca ggctatcaat
    14761 tttgcttttg acagaacatc ttatggggct cagtctgaag ggaaagaagg tgcaacaaag
    14821 attttgcgta acctagtggt tcctccaaac tttgtcagta tcaagggaaa agactttggt
    14881 gaagttgtag tctctaagat ggtcaactat ggtaaggaat ggcaaggtat caactttgcg
    14941 gatggtcaag acccttacta caatcctgag aaagccaagg ctaagtttgc ggaagctaag
    15001 aaagaactcg aagcaaaggg tgttcaattc ccaatccact tggataagac tgtggaagta
    15061 acagataaag taggcataca aggagttagt tctatcaaac aatcaattga atctgtttta
    15121 ggttctgata atgtagtgat tgacattcag caattaacat cagatgagtt tgacagttca
    15181 ggctactttg ctcaaacagc tgctcagaaa gactatgatt tatatcatgg cggttgggga
    15241 cctgattatc aagacccgtc aacctatctc gatattttta atactaatag tggaggagtt
    15301 ctacaaaatc ttggactaga gcctggagaa gccaatgaca aggctaagga agttggactg
    15361 gatgtctata ctcaaatgtt ggaagaagct aataaagagc aagatccagc caaacgttat
    15421 gagaaatatg ctgatattca agcttggttg attgatagtt ctttagttct tccaagtgtt
    15481 tcgcgtgggg gaacaccatc attgagaaga accgtaccat ttgctgctgc ctatggttta
    15541 accggtacaa aagggattga atcatataaa tacctcaaag tacaagataa gattgtcaca
    15601 acagacgaat atgcaaaagc tagagaaaaa tggttgaaag aaaaagaaga atccaataaa
    15661 aaagcccaag aagaattggc aaaacatgtc aaataaaatc taattgtaga taagtttgtg
    15721 taagaagtct ttgtgcttaa aaacgcataa tatcaggtat ataaaatcct agatgttatg
    15781 cgttttgtta taggaagatt tattagattt tatcctcaaa ttgagttatt cccgacttta
    15841 tccgttgaaa tattataagg agtatttatg aaattaaaat tattaagagt agatactaag
    15901 gtgattatgg ggagtttctt acttgttctg tctagtctac ttgctttgtt gcttcccctt
    15961 atcttaaagg gtttaataga tgggagttct attgaaaata taggttccaa agtatttcaa
    16021 tcgtttttga tttttattgg tcaagccttg ttttcttcta ttggttacta tctgtttagt
    16081 caatcgggtg aaaaaaagat agcaaaaatc aggaaaaaag tgatagaggg gttgatttat
    16141 gcagagaaat ccttctttga taagagccaa agtggggagt tgacttctgc cattgtcaat
    16201 gacacgagtg tcattcgtga gtttttaatt acgactttcc caaatattat tctgagttta
    16261 gttatggtac ttggttccat tgtagtctta tttagtcttg attggaatct ttctctactt
    16321 ttattcatca ctcttccttg tatgatgttt attatcttgc tcctttccaa tatcagtgaa
    16381 aagtatagtc gtcgtttaca ggaggaaatc ggatttttaa cagggtaatt gactgaaaag
    16441 attcaagaac atgaattaat taagactaac caagcagaga aaagtgtaca ggatgttttg
    16501 gataattgta ttgaaagggt acaaaacaat tcactgaaat cagatagggt tacttctttt
    16561 gagaccccgt ttgctctctt atttatcttt gcgactatag ctgtgatgct aacctatggg
    16621 ggttatcggg tcagcgcagg atatatatct gtgggaacct tggtttcgtt tttgatttac
    16681 ctctttcaat tacttaatcc tattagtaat atagctaatt ttgtaactgt ttattctagg
    16741 agcaagggat cttcagttgc actggagaac ttgcttgcag ttcctaaaga aaaatttgag
    16801 tgaggaaaat cggtatcagg acaagggttg aattt
//
LOCUS       DAVBOD010000047        16461 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 640-05
            SAMEA1012484-rid20186543.denovo.047, whole genome shotgun sequence.
ACCESSION   DAVBOD010000047 DAVBOD010000000
VERSION     DAVBOD010000047.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012484
            Sequence Read Archive: ERR059358
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 16461)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16461)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979948.1
            Genome Coverage       :: 595x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:03:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,266
            CDSs (total)                      :: 2,219
            Genes (coding)                    :: 2,091
            CDSs (with protein)               :: 2,091
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 71 of 128
            Pseudo Genes (incomplete)         :: 50 of 128
            Pseudo Genes (internal stop)      :: 33 of 128
            Pseudo Genes (multiple problems)  :: 22 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16461
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012484-rid20186543.denovo.047"
                     /strain="NIG 640-05"
                     /db_xref="taxon:1313"
     gene            <1..906
                     /gene="lytB"
                     /locus_tag="VQ862_001609"
     CDS             <1..906
                     /gene="lytB"
                     /locus_tag="VQ862_001609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010976495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endo-beta-N-acetylglucosaminidase"
                     /protein_id="HET3115926.1"
                     /translation="YMAKNETVDGYQLGSDGKWLGGKATNENAAYYQVVPVTANVYDS
                     DGEKLSYISQGSVVWLDKDRKSDDKRLAITISGLSGYMKTEDLQALDASKDFIPYYES
                     DGHRFYHYVAQNASIPVASHLSDMEVGKKYYSADGLHFDGFKLENPFLFKDLTEATNY
                     SAEELDKVFSLLNINNSLLENKGATFKEAEEHYHINALYLLAHSALESNWGRSKIAKD
                     KNNFFGITAYDTTPYLSAKTFDDVDKGILGATKWIKENYIDRGRTFLGNKASGMNVEY
                     ASDPYWGEKIASVMMKINEKLGGKD"
     gene            complement(967..2622)
                     /gene="pavA"
                     /locus_tag="VQ862_001610"
     CDS             complement(967..2622)
                     /gene="pavA"
                     /locus_tag="VQ862_001610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_094859469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rqc2 family fibronectin-binding protein PavA"
                     /protein_id="HET3115927.1"
                     /translation="MSFDGFFLHHIVEELRSELVNGRIQKINQPFEQELVLQIRSNRQ
                     SHRLLLSAHPVFGRIQLTQTTFENPAQPSTFIMVLRKYLQGALIESIEQVENDRIVEI
                     TVSNKNEIGDHIQATLIIEIMGKHSNILLVDKSSHKILEVIKHVGFSQNSYRTLLPGS
                     TYIAPPSTKSLNPFTIKDEKLFEILQTQELTAKNLQSLFQGLGRDTANELERILVSEK
                     LSAFRNFFNQETKPCLTETSFSPVPFANQVGEPLANLSDLLDTYYKDKAERDRVKQQA
                     SELIRRVENELQKNRHKLKKQEKELLATDNAEEFRQKGELLTTFLHQVPNDQDQVILD
                     NYYTNQPIMIALDKALTPNQNAQRYFKRYQKLKEAVKYLTDLIEETKATILYLESVET
                     VLNQAGLEEIAEIREELIQTGFIRRRQREKIQKRKKLEQYLASDGKTIIYVGRNNLQN
                     EELTFKMARKEELWFHAKDIPGSHVVISGNLDPSDAVKTDAAELAAYFSQGRLSNLVQ
                     VDMIEVKKLNKPTGGKPGFVTYTGQKTLRVTPDSKKIASMKKS"
     gene            2727..3224
                     /gene="ybeY"
                     /locus_tag="VQ862_001611"
     CDS             2727..3224
                     /gene="ybeY"
                     /locus_tag="VQ862_001611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018380869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA maturation RNase YbeY"
                     /protein_id="HET3115928.1"
                     /translation="MYIEMVDETGQVSKEMLQQTQEILEFAAQKLGKEDKEMAVTFVT
                     NERSHELNLEYRDTDRPTDVISLEYKPELEIAFDEEDLLENPELAEMMSEFDAYIGEL
                     FISIDKAHEQAEEYGHSFEREMGFLAVHGFLHINGYDHYTPEEEAEMFGLQEEILTAY
                     GLTRQ"
     gene            3205..3600
                     /locus_tag="VQ862_001612"
     CDS             3205..3600
                     /locus_tag="VQ862_001612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000378166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HET3115929.1"
                     /translation="MDSQDNKRKWKNRDLISSLEFALTGIFTAIKEERNMRKHAVTAL
                     VVILAGFVFQVSRIEWLFLLLSIFLVVAFEIINSAIENVVDLASHYHFSMLAKNAKDM
                     AAGAVLVVSLFAALTGALIFLPRIWDLLF"
     gene            3617..4516
                     /gene="era"
                     /locus_tag="VQ862_001613"
     CDS             3617..4516
                     /gene="era"
                     /locus_tag="VQ862_001613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase Era"
                     /protein_id="HET3115930.1"
                     /translation="MTFKSGFVAILGRPNVGKSTFLNHVMGQKIAIMSDKAQTTRNKI
                     MGIYTTDKEQIVFIDTPGIHKPKTALGDFMVESAYSTLREVDTVLFMVPADEARGKGD
                     DMIIERLKAAKVPVILVVNKIDKVHPDQLLSQIDDFRNQMDFKEIVPISALQGNNVSR
                     LVDILSENLDEGFQYFPSDQITDHPERFLVSEMVREKVLHLTREEIPHSVAVVVDSMK
                     RDEETDKVHIRATIMVERDSQKGIIIGKGGAMLKKIGSMARRDIELMLGDKVFLETWV
                     KVKKNWRDKKLDLADFGYNEREY"
     gene            4565..5389
                     /gene="mutM"
                     /locus_tag="VQ862_001614"
     CDS             4565..5389
                     /gene="mutM"
                     /locus_tag="VQ862_001614"
                     /EC_number="3.2.2.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001114577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-formamidopyrimidine glycosylase"
                     /protein_id="HET3115931.1"
                     /translation="MPELPEVETVCRGLEKLIIGKKISSIEIRYHKMIKTDLEEFQRE
                     LPSQIIESMGRRGKYLLFCLTDKVLISHLRMEGKYFYYPDQVPERKHAHVFFRFEDGG
                     TLVYEDVRKFGTMELLVPDLLDAYFISKKLGPEPSEQDFDLQVFQAALAKSKKPIKSH
                     LLDQTLVAGLGNIYVDEVLWRAQVHPARPSQTLTAEEATAIHDQTIAVLGQAVEKGGS
                     TIRTYTNAFGEDGSMQDFHQVYDKTGQECVRCGTIIEKIQLGGRGTHFCPNCQRRD"
     gene            5389..5994
                     /locus_tag="VQ862_001615"
     CDS             5389..5994
                     /locus_tag="VQ862_001615"
                     /EC_number="2.7.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dephospho-CoA kinase"
                     /protein_id="HET3115932.1"
                     /translation="MGKIIGITGGIASGKSTVTNFLRQQGFQAVDADAVVHQLQKPGG
                     RLFEALVQHFGQEIILENGELNRPLLASLIFSNPEEQKWSNQIQGEIIREELATLREQ
                     LAQTEEIFFMDIPLLFEQDYSDWFAETWLVYVDRDAQVERLMKRDQLSKDEAESRLAA
                     QWPLEKKKDLASQVLDNNGNQNQLLNQVHILLEGGRQDDRD"
     gene            5981..7180
                     /locus_tag="VQ862_001616"
     CDS             5981..7180
                     /locus_tag="VQ862_001616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter PmrA"
                     /protein_id="HET3115933.1"
                     /translation="MTEINWKDNLRIAWFGNFLTGASISLVVPFMPIFVENLGVGSQQ
                     VAFYAGLAISVSAISAALFSPIWGILADKYGRKPMMIRAGLAMTITMGGLAFVPNIYW
                     LIFLRLLNGVFAGFVPNATALIASQVPKEKSGSALGTLSTGVVAGTLTGPFIGGFIAE
                     LFGIRTVFLLVGSFLFLAAILTICFIKEDFQPVAKEKAIPTKELFTSVKYPYLLLNLF
                     LTSFVIQFSAQSIGPILALYVRDLGQTENLLFVSGLIVSSMGFSSMMSAGVMGKLGDK
                     VGNHRLLVVAQFYSVIIYLLCANASSPLQLGLYRFLFGLGTGALIPGVNALLSKMTPK
                     AGISRVFAFNQVFFYLGGVVGPMAGSAVAGQFGYHAVFYATSLCVAFSCLFNLIQFRT
                     LLKVKEI"
     gene            7180..7329
                     /gene="rpmG"
                     /locus_tag="VQ862_001617"
     CDS             7180..7329
                     /gene="rpmG"
                     /locus_tag="VQ862_001617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HET3115934.1"
                     /translation="MRVKINLKCSSCGSINYLTSKNSKTHPDKIEVLKYCPKERKVTL
                     HLESK"
     gene            7369..7602
                     /gene="secG"
                     /locus_tag="VQ862_001618"
     CDS             7369..7602
                     /gene="secG"
                     /locus_tag="VQ862_001618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecG"
                     /protein_id="HET3115935.1"
                     /translation="MYNLLLTILLVLSVVIVIAIFMQPTKNQSSNVFDASSGDLFERS
                     KARGFEAVMQRLTGILVFFWLAIALALTVLSSR"
     gene            7704..10058
                     /gene="rnr"
                     /locus_tag="VQ862_001619"
     CDS             7704..10058
                     /gene="rnr"
                     /locus_tag="VQ862_001619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000653285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease R"
                     /protein_id="HET3115936.1"
                     /translation="MKDRIKEYLQDKGKVTVNDLAQALGKDSSKDFRELIKTLSLMER
                     KHQIRFEEDGSLKLEIKKKHEITLKGIFHAHKNGFGFVSLEGEEDDLFVGKNDVNYAI
                     AGDTVEVVIKKVADRNKGTAAEAKIIDILEHSLTTVVGQIVLDQEKPKYAGYIRSKNQ
                     KISQPIYVKKPALKLEGTEVLKVFIDKYPSKKHDFFVASVLDVVGHSTDVGIDVLEVL
                     ESMDIVSEFPEAVVKEAESVPDAPSQKDMEGRLDLRDEITFTIDGADAKDLDDAVHIK
                     ALKNGNLELGVHIADVSYYVTEGSALDKEALNRATSVYVTDRVVPMLPERLSNGICSL
                     NPQVDRLTQSAIMEIDKHGRVVNYTITQTVIKTSFRMTYSDVNDILAGDEEKRKKYHK
                     IVPSIELMAKLHETLENMRVKRGALNFDTNEAKILVDKQGKPVDIVLRQRGIAERMIE
                     SFMLMANETVAEHFSKLDLPFIYRIHEEPKAEKVQKFIDYASSFGLRIYGTASEISQE
                     ALQDIMRAVEGESYADVLSMMLLRSMQQARYSEHNYGHYGLAADYYTHFTSPIRRYPD
                     LLVHRMIRDYGRSKEIAEHFEQVIPEIATQSSNRERRAIEAEREVEAMKKAEYMEEYV
                     GEEYDAVVSSIVKFGLFVELPNTVEGLIHITNLPEFYHFNERDLTLRGEKSGITFRVG
                     QQIRIRVERADKMTGEIDFSFVPSEFDVIEKGLKQSSRSGRGRGSNRRSDKKEDKRKS
                     GRSNDKRKHSQKDKKKKGKKPFYKEVAKKGAKHGKGRGKGRRTK"
     gene            10021..10488
                     /gene="smpB"
                     /locus_tag="VQ862_001620"
     CDS             10021..10488
                     /gene="smpB"
                     /locus_tag="VQ862_001620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SsrA-binding protein SmpB"
                     /protein_id="HET3115937.1"
                     /translation="MAKGEGKVVAQNKKARHDYTIVDTLEAGMVLTGTEIKSVRAARI
                     NLKDGFAQVKNGEVWLSNVHIAPYEEGNIWNQEPERRRKLLLHKRQIQKLEQETKGTG
                     MTLVPLKVYIKDGYAKLLLGLAKGKHDYDKRESIKRREQNRDIARVMKAVNQR"
     gene            10504..11364
                     /gene="tehB"
                     /locus_tag="VQ862_001621"
     CDS             10504..11364
                     /gene="tehB"
                     /locus_tag="VQ862_001621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000413836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent methyltransferase TehB"
                     /protein_id="HET3115938.1"
                     /translation="MEKLVAYKRMPLWNKQTMPEAVQQKHNTKVGTWGKITVLKGALK
                     FIELTEEGEVLAEHLFEAGADNPMAQPQAWHRVEAATDDVEWYLEFYCKPEDYFAKKY
                     NTNPVHSEVLEAMETVKQGKALDLGCGQGRNSLFLAQQDFDVTAVDQNGLALEILQSI
                     VEQEDLDMPVGLYDINSASIEQEYDFIVSTVVLMFLQADRIPAIIQNMQEKTSVGGYN
                     LIVCAMDTEDYPCSVNFPFTFKEGELADYYKDWELVKYNENPGHLHRRDENGNRIQLR
                     FATLLAKKIK"
     gene            11437..12390
                     /gene="coiA"
                     /locus_tag="VQ862_001622"
     CDS             11437..12390
                     /gene="coiA"
                     /locus_tag="VQ862_001622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000495911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein CoiA"
                     /protein_id="HET3115939.1"
                     /translation="MFVARDARGELVNVLEDKLEKQAYTCPACGGQLHLRQGPSVRTH
                     FAHKSLKDCDFFFENESPEHLANKESLYHWLKKETKVQLEYPLSELKQIADVFVNGNL
                     ALEVQCSPLPQKVLKERSEGYRSQGYQVLWLLGQKLWLKERLTRLQQGFLYFSQNMGF
                     YVWELDKEKQVLRLKYLIYQDLRGKLHYQIKEFSYGQGSLLEILRLPYKRQKISHFTV
                     SEDKDICRYIRQQLYYQNLFWMKEQAEAYQKGENILTYGLKEWYPQIRPIVGKFFQIE
                     QDLTSYYQHFYTYYQKNPQNDWQKLYPPAFYQQYFLKNMVE"
     gene            12409..14211
                     /gene="pepF"
                     /locus_tag="VQ862_001623"
     CDS             12409..14211
                     /gene="pepF"
                     /locus_tag="VQ862_001623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HET3115940.1"
                     /translation="MVLQRNEINEKDTWDLSTIYPTDQAWEEALKDLTEQLETVAQYE
                     GHLLDSADNLLEITEFSLEMERQIEKLYVYAHMKNDQDTREAKYQEYYAKAMTLYSQL
                     DQAFSFYEPEFMEISEKQYADFLEAQPKLQVYQHYFDKLLQGKDHVLSQREEELLAGA
                     GEIFGSASETFAILDNADIVFPYVLDDDGKEVQLSHGTYTRLMESKKREVRRGAYQAL
                     YATYEQFQHTYAKTLQTNVKVQNYRAKVRNYKSARHAALAANFVPESVYDNLVAAVRK
                     HLPLLHRYLELRSKILGISDLKMYDVYTPLSSVEYSFTYQEALKKAEDALAVLGEDYL
                     SRVKRAFSERWIDVYENQGKRSGAYSGGSYDTNAFMLLNWQDNLDNLFTLVHETGHSM
                     HSSYTRETQPYVYGDYSIFLAEIASTTNENILTEKLLEEVEDDATRFAILNNFLDGFR
                     GTVFRQTQFAEFEHAIHQADQNGEVLTSDFLNKLYADLNQEYYGLSKEDNPEIQYEWA
                     RIPHFYYNYYVYQYSTGFAAASALAEKIVHGSQEDRDRYIDYLKAGKSDYPLNVMRKA
                     GVDMEKEDYLNDAFAVFERRLNEFEALVEKLGLA"
     gene            14213..14926
                     /locus_tag="VQ862_001624"
     CDS             14213..14926
                     /locus_tag="VQ862_001624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-methyltransferase"
                     /protein_id="HET3115941.1"
                     /translation="MVESYSKNANHNMRRPVVKEEIVDLMRQRQKQVTGFLKELEDFA
                     RKENIPIIPHETVAYFRFLMETMQPKNILEIGTAIGFSALLMAEHAPNAKITTIDRNP
                     EMIGFAKENFAQFDSRKQITLLEGDAVDVLSTLTESYDFVFMDSAKSKYIVFLPEILK
                     HLEVGGVVVLDDIFQGGDVAKDIMEVRRGQRTIYRGLQKLFDATLDNPELTATLVPLG
                     DGILMLRKNVADVQLSESE"
     gene            14993..15934
                     /gene="prsA"
                     /locus_tag="VQ862_001625"
     CDS             14993..15934
                     /gene="prsA"
                     /locus_tag="VQ862_001625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase PrsA"
                     /protein_id="HET3115942.1"
                     /translation="MKKKLLAGAITLLSVATLAACSKGSEGADLISMKGDIITEHQFY
                     EQVKNNPSAQQVLLNMTIQKVFEKQYGSELDDKEVDDTIAEEKKQYGENYQRVLSQAG
                     MTLETRKAQIRTSKLVELAVKKVAEAELTDEAYKKAFDEYTPDVTAQIIRLNNEDKAK
                     EVLEKAKAEGADFAQLAKDNSTDEKTKENGGEITFDSASTEVPEQVKKAAFALDVDGV
                     SDVITATGTQAYSSQYYIVKLTKKTEKSSNIDDYKEKLKTVILTQKQNDSTFVQSIIG
                     KELQAANIKVKDQAFQNIFTQYIGGGDSSSSSSTSNE"
     gene            complement(16051..16392)
                     /locus_tag="VQ862_001626"
                     /pseudo
     CDS             complement(16051..16392)
                     /locus_tag="VQ862_001626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
BASE COUNT         4951 a         3076 c         3688 g         4746 t
ORIGIN      
        1 tacatggcga aaaatgagac agtagatggt tatcagcttg gaagcgatgg taaatggctt
       61 ggaggaaaag ctacaaatga aaatgctgct tactatcaag tagtgcctgt tacagccaat
      121 gtttatgatt cagatggtga aaagctttcc tatatatcgc aaggtagtgt cgtatggcta
      181 gataaggata gaaaaagtga tgacaagcgc ttggctatta ctatttctgg tttgtcaggc
      241 tatatgaaaa cagaagattt acaagcgcta gatgctagta aggactttat cccttattat
      301 gagagtgatg gccaccgttt ttatcactat gtggctcaga atgctagtat cccagtagct
      361 tctcatcttt ctgatatgga agtaggcaag aaatattatt cggcagatgg cctgcatttt
      421 gatggtttta agcttgagaa tcccttcctt ttcaaagatt taacagaggc tacaaactac
      481 agtgctgaag aattggataa ggtatttagt ttgctaaaca ttaacaatag ccttttggag
      541 aacaagggcg ctacttttaa ggaagccgaa gaacattacc atatcaatgc tctttatctc
      601 cttgcccata gtgccctaga aagtaactgg ggaagaagta aaattgccaa agataagaat
      661 aatttctttg gcattacagc ctatgatacg accccttacc tttctgctaa gacatttgat
      721 gatgtggata agggaatttt aggtgcaacc aagtggatta aggaaaatta tatcgatagg
      781 ggaagaactt tccttggaaa caaggcttct ggtatgaatg tggaatatgc ttcagaccct
      841 tattggggcg aaaaaattgc tagtgtgatg atgaaaatca atgagaagct aggtggcaaa
      901 gattagtact ataagtgaat atgatttgag tgaatagtaa gttaaaaatc ctgatttcaa
      961 gtaaaatcag gattttttca tggatgcaat ttttttggag tctggtgtga cgcggagggt
     1021 cttttgtcct gtgtaagtga caaagccggg ttttccacca gttggtttat tgagtttttt
     1081 gacttcaatc atatctacct gcaccagatt cgacaggcgc ccttgagaga agtaggcagc
     1141 taactctgct gcgtctgtct tgactgcatc agatgggtca agatttcctg agatgacaac
     1201 atggcttcca ggaatgtcct tagcatggaa ccaaagttcc tccttgcggg ccattttaaa
     1261 ggtcaattcc tcattttgaa gattgtttcg tccgacatag atgatggttt tgccatcgct
     1321 tgctagatat tgttctagtt ttttgcgttt ctggattttc tcccgttgtc ttctgcggat
     1381 aaaacctgtt tgaatcaatt cttcacggat ttcagcgatt tcttccagtc cagcttggtt
     1441 gaggacggtt tctacacttt ccagatagag aatagtggct ttggtttctt caatcaaatc
     1501 agtcaagtat ttgacagctt ctttgagttt ctgataccgt ttaaaatagc gttgggcatt
     1561 ctggttggga gtcagagcct tatcaagcgc aatcatgata ggttggttgg tatagtagtt
     1621 gtctaggata acctggtctt ggtcgttagg cacttggtgg aggaaggttg tcagcaattc
     1681 tcctttttga cgaaattctt cagcgttgtc tgtcgccagt aactcttttt cctgtttttt
     1741 gagtttgtgt cggtttttct gaagttcatt ttcaacacga cgaatcagtt cactggcctg
     1801 ctgtttgacg cggtcgcgct cagccttatc cttatagtag gtgtccaaca aatcagaaag
     1861 atttgcaaga ggctctccca cctgatttgc aaaaggaact ggactgaagg aagtctcagt
     1921 caagcatggc ttggtttctt gattgaaaaa atttcggaaa gcggaaagtt tttcactaac
     1981 cagtatcctt tccaattcat ttgccgtatc gcgtcccaga ccttgaaaga ggctttgaag
     2041 attttttgct gttagttctt gggtttgcag gatttcaaag agcttttcat ccttgatagt
     2101 aaaaggattg agagattttg tacttggcgg agcgatatag gtcgatcctg gaagtaaggt
     2161 gcggtagcta ttttgtgaaa agccgacgtg tttgataact tcgaggattt tatgactgct
     2221 tttatcgacc agtagaatat tactgtgttt ccccataatt tcgataatca aggtagcctg
     2281 gatatggtct ccaatctcgt ttttattgga aactgtaatt tccacaatac ggtcattttc
     2341 cacttgctca atcgactcaa tcagggcccc ctgcaaatac tttctcaaaa ccatgataaa
     2401 ggtagaaggt tgggctggat tttcaaaagt cgtttgggtc agctgaatgc gtccaaaaac
     2461 tggatgggca gaaaggagca ggcgatggct ttggcgattg ctgcggattt gcaagaccaa
     2521 ctcttgttca aaaggctgat tgattttctg gatgcgacca ttcactaatt cgcttcgcaa
     2581 ttcctcaact atgtggtgta aaaaaaatcc gtcaaatgac atcgttctct ccttgtgatt
     2641 gtattccata gtattatatc aaaaaggtag aataaaatca tggaaatgtg gtataataaa
     2701 gccaagtaaa gagaaacgag aagcacatgt atattgaaat ggtagatgaa actggtcaag
     2761 tttcaaaaga aatgttgcaa caaacccaag aaattttgga atttgcagcc caaaaattag
     2821 gaaaagaaga caaggagatg gcagtcactt ttgtgaccaa tgagcgtagt catgaactta
     2881 atctggagta ccgtgacacc gaccgtccga cagatgtcat cagccttgag tataaaccag
     2941 aattggaaat tgcctttgac gaagaggatt tgcttgaaaa tccagaattg gcagagatga
     3001 tgtctgagtt tgatgcctat attggggaat tgttcatctc tatcgataag gctcatgagc
     3061 aggccgaaga atatggtcac agctttgagc gtgagatggg cttcttggca gtacacggct
     3121 ttttacatat taacggctat gatcactaca ctccggaaga agaagcggag atgttcggtt
     3181 tacaagaaga aattttgaca gcctatggac tcacaagaca ataaacgaaa atggaaaaat
     3241 cgtgacttga tatccagttt agaatttgct ttgacaggta tttttactgc tatcaaggaa
     3301 gaacgcaata tgcgaaaaca cgcagtgacg gctctagtgg tcatccttgc aggttttgtt
     3361 tttcaggtgt cacgaatcga atggctcttt ctcctattga gtattttctt ggtagtagcc
     3421 tttgagatta tcaactctgc tattgaaaat gtggtggatt tggccagtca ctatcacttt
     3481 tccatgctgg ctaaaaatgc caaggatatg gcggctggcg cggtattagt ggtttctctt
     3541 ttcgcagcct taacaggcgc attgattttt ctcccacgaa tctgggattt attattttaa
     3601 acagtaagag gaaattatga cttttaaatc aggctttgta gccattttag gacgtcccaa
     3661 tgttgggaag tcaacctttt taaatcacgt tatggggcaa aagattgcca tcatgagtga
     3721 caaggcgcag acaacgcgca ataaaatcat gggaatttac acgactgata aggagcaaat
     3781 tgtctttatc gacacaccag ggattcacaa acctaaaaca gctctcggag atttcatggt
     3841 tgagtctgcc tacagtaccc ttcgcgaagt ggacaccgtt cttttcatgg tgcctgctga
     3901 tgaagcgcgt ggtaaggggg acgatatgat tatcgagcgt ctcaaggctg ccaaggttcc
     3961 tgtgattttg gtggtgaata aaatcgataa ggtccatcca gaccagctct tgtctcagat
     4021 tgatgacttc cgtaatcaaa tggactttaa ggaaattgtt ccaatctcag cccttcaggg
     4081 aaataacgtg tctcgtctag tggatatttt gagtgaaaat ctggatgaag gtttccaata
     4141 tttcccgtct gatcaaatca cagaccatcc agaacgtttc ttagtttcag aaatggttcg
     4201 cgagaaagtc ttgcacctaa ctcgtgaaga gattccgcat tctgtagcag tagttgttga
     4261 ctctatgaaa cgagacgaag agacagacaa ggttcacatc cgtgcaacca tcatggtcga
     4321 gcgcgatagc caaaaaggga ttatcatcgg taaaggtggc gctatgctta agaaaatcgg
     4381 tagcatggcc cgtcgtgata tcgaactcat gctaggagac aaggtcttcc tagaaacctg
     4441 ggtcaaggtc aagaaaaact ggcgcgataa aaagctagat ttggctgact ttggctataa
     4501 tgaaagagaa tactaagtag aggtaggctc atgcctgctt cttgttttta cagaaggagg
     4561 acttatgcct gaattacctg aggttgaaac cgtttgtcgt ggcttagaaa aattgattat
     4621 aggaaagaag atttcgagta tagaaattcg ctaccacaag atgattaaga cggatttgga
     4681 agagtttcaa agggaattgc ctagtcagat tatcgagtca atgggacgtc gtggaaaata
     4741 tttgcttttc tgcctgacag acaaggtctt gatttcccat ttgcggatgg agggcaagta
     4801 tttttattat ccagaccaag tgcctgaacg caagcatgcc catgttttct tccggtttga
     4861 agatgggggc acgcttgttt atgaggatgt acgcaagttt ggaaccatgg aactcttggt
     4921 gcctgacctt ttagacgcct actttatttc taaaaaatta ggtcctgaac caagcgaaca
     4981 agactttgat ttacaggtct ttcaagctgc ccttgccaag tccaaaaagc ctatcaaatc
     5041 ccatctccta gaccagacct tggtagctgg acttggcaat atctatgtgg atgaggttct
     5101 ctggcgagct caggttcatc cagctagacc ttcccagact ttgacagcag aagaagcgac
     5161 tgccattcat gaccagacca ttgctgtttt gggccaggct gttgaaaaag gcggttccac
     5221 cattcggacc tataccaatg cctttgggga agatggaagc atgcaggatt ttcatcaggt
     5281 ctatgataag actggtcaag aatgtgtacg ctgtggtacc atcattgaga aaattcaact
     5341 aggcggacga ggcacccact tttgtccaaa ctgtcaaagg agggactgat gggaaaaatc
     5401 atcggaatca ctgggggaat tgcctcaggt aagtcaactg tgacaaattt tctaagacag
     5461 caaggctttc aagcagtgga tgccgacgca gtcgtccacc aactacagaa acctggtggt
     5521 cgtctgtttg aggctctagt acagcacttt gggcaagaaa tcattcttga aaacggagaa
     5581 ctcaatcgcc ctctcctagc tagtctcatc ttttcaaatc ctgaagagca aaaatggtct
     5641 aatcaaattc aaggggagat tatccgtgag gaactggcta ctttgagaga acagttggct
     5701 cagacagaag agattttctt catggatatt cccctacttt ttgagcagga ctacagcgat
     5761 tggtttgctg agacttggtt ggtctatgtg gaccgagatg cccaagtaga acgcttaatg
     5821 aaaagggacc agttgtccaa agatgaagct gagtctcgtc tggcagccca gtggccttta
     5881 gaaaaaaaga aagatttggc cagccaggtt cttgataata atggcaatca gaaccaactt
     5941 cttaatcaag tgcatatcct tcttgaggga ggtaggcaag atgacagaga ttaactggaa
     6001 ggataatctg cgtattgcct ggtttggtaa ttttctgaca ggagccagta tttctttggt
     6061 tgtacctttt atgcccatct tcgtggaaaa tctaggtgta gggagtcagc aagtcgcttt
     6121 ttatgcaggc ttagcaattt ctgtctctgc tatttccgcg gcgctctttt ctcctatttg
     6181 gggtattctt gctgacaaat acggccgaaa acccatgatg attcgggcag gtcttgctat
     6241 gactatcact atgggaggct tggcctttgt cccaaatatc tattggttaa tctttcttcg
     6301 tttactaaac ggtgtatttg caggttttgt tcctaatgca acggcactga tagccagtca
     6361 ggttccaaag gagaaatcag gctctgcctt aggtactttg tctacaggcg tagttgcagg
     6421 cactctaact ggtcccttta ttggtggctt tatcgcagaa ttatttggca ttcgtacagt
     6481 tttcttactg gttggtagtt ttctattttt agctgctatt ttgactattt gctttatcaa
     6541 ggaagatttt caaccagtag ccaaggaaaa ggctattcca acaaaggaat tatttacctc
     6601 ggttaaatat ccctatcttt tgctcaatct ctttttaacc agttttgtca tccaattttc
     6661 agctcaatcg attggcccta ttttggctct ttatgtacgc gacttagggc agacagagaa
     6721 tcttcttttt gtctctggtt tgattgtgtc cagtatgggc ttttccagca tgatgagtgc
     6781 aggagtcatg ggcaagctag gtgacaaggt gggcaatcat cgtctcttgg ttgtcgccca
     6841 gttttattca gtcatcatct atctcctctg tgccaatgcc tctagccccc ttcaactagg
     6901 actctatcgt ttcctctttg gattgggaac cggtgccttg attcccgggg ttaatgccct
     6961 actcagcaaa atgactccca aagccggcat ttcgagggtc tttgccttca atcaggtatt
     7021 cttttatctg ggaggtgttg ttggtcccat ggcaggttct gcagtagcag gtcaatttgg
     7081 ctaccatgct gtcttttatg cgacgagcct ttgtgttgcc tttagttgtc tctttaacct
     7141 gattcaattt cgaacattat taaaagtaaa ggaaatctag tgcgagtaaa aattaatctc
     7201 aaatgctcct cttgtggcag tatcaattac ctaaccagta aaaattcaaa aacccatcca
     7261 gacaagattg aggttttaaa gtattgtccc aaggaaagaa aagtaaccct acatcttgaa
     7321 tctaagtaga ttttatggta aaataatagg gattttaagg agtttgatat gtataaccta
     7381 ttattaacca ttttattagt attatctgtt gtgattgtga ttgcaatttt catgcaacca
     7441 accaaaaacc aatccagcaa tgtatttgat gccagttcag gtgatttgtt tgaacgcagt
     7501 aaagctcgcg gttttgaagc tgtaatgcag cgtttgacag ggattttagt ctttttctgg
     7561 ctagccattg ccttagcatt gacggtatta tcaagtagat aagaaaataa tgggcaggac
     7621 taggtctttg cctcttttta tttttaaagg atgtttgaga aggttttaca gtaaaagaaa
     7681 attaaaaaat ctagaaagaa aatatgaaag atagaataaa agaatattta caagacaagg
     7741 gaaaggtgac tgttaatgat ttggctcagg ctttgggaaa agacagttcc aaggattttc
     7801 gtgagttgat taaaaccttg tccttaatgg aaagaaagca ccaaattcgt tttgaagaag
     7861 atggtagtct gaaattagaa attaagaaaa aacatgagat taccctcaag gggatttttc
     7921 atgcccataa aaatggcttt ggctttgtta gtctggaagg cgaggaggac gacctttttg
     7981 tagggaaaaa tgatgtcaac tatgctattg ctggtgatac cgtcgaggta gtgattaaga
     8041 aagtcgctga ccgcaataag ggaacagcag cagaagccaa aattattgat atcctagaac
     8101 acagtttgac aacagttgtc gggcaaatcg ttctggatca ggaaaaacct aagtatgctg
     8161 gctatattcg ttcaaaaaat cagaaaatca gtcaaccgat ttatgttaag aaaccagccc
     8221 taaaattaga aggaacagaa gttctcaaag tctttatcga taaataccca agcaagaaac
     8281 atgatttctt tgtcgcgagt gttctcgatg tggtgggaca ctcaacggat gtcggaattg
     8341 atgttcttga ggttttggaa tcaatggaca ttgtatccga gtttccagaa gctgttgtta
     8401 aggaagcaga aagtgtgcct gatgctccgt ctcaaaagga tatggaaggt cgtctggatc
     8461 taagagatga aattaccttt accattgacg gtgcggatgc caaggacttg gacgatgcag
     8521 tgcatatcaa ggctctgaaa aatggcaatc tggagcttgg ggttcacatc gcagatgttt
     8581 cttattatgt gaccgagggg tctgcccttg acaaggaagc ccttaaccgt gcgacttctg
     8641 tttacgtgac agaccgagtg gtgccaatgc ttccagaacg actatcaaat ggcatctgct
     8701 ctctcaatcc ccaagttgac cgcctgaccc agtctgctat tatggagatt gataaacatg
     8761 gtcgtgtggt caactatacc attacacaaa cagttatcaa gaccagtttt cgtatgacct
     8821 atagcgatgt caatgatatc ctagctggcg atgaagaaaa gagaaaaaaa tatcataaaa
     8881 ttgtaccaag tatcgaactc atggccaagc ttcatgaaac tttagaaaac atgcgtgtga
     8941 aacgtggagc tctcaatttt gataccaatg aagcgaagat tttagtggat aaacaaggta
     9001 agcctgttga tatcgttctt cggcagcgtg gtattgccga gcggatgatt gagtctttta
     9061 tgttgatggc taatgaaaca gttgccgaac atttcagcaa gttggatttg ccttttatct
     9121 atcgaattca cgaggagcct aaggctgaaa aggttcagaa gtttattgat tatgcttcga
     9181 gttttggctt gcgcatttat gggactgcca gtgagattag tcaggaggca cttcaagaca
     9241 tcatgcgtgc tgttgaggga gaatcttatg cagatgtatt gtccatgatg cttcttcgct
     9301 ctatgcagca ggctcgttat tcggagcaca attacggcca ctatggacta gctgctgact
     9361 attatactca ctttaccagt ccaattcgtc gttatccaga ccttcttgtt caccgtatga
     9421 ttcgggatta cggccgttct aaggaaatag cagagcattt tgaacaagtg attccagaga
     9481 ttgcgaccca gtcttccaac cgtgaacgtc gtgccataga agctgagcgt gaagtcgaag
     9541 ccatgaaaaa ggctgagtat atggaagaat acgtgggtga agagtatgat gcagttgtat
     9601 caagtattgt caaattcggt ctctttgtcg aattgccaaa cacagttgaa ggcttgattc
     9661 acatcactaa tctacctgaa ttttatcatt tcaatgagcg tgatttgact cttcgtggag
     9721 aaaaatcagg tatcactttc cgagtgggtc agcagatccg tatccgtgtt gaaagagcgg
     9781 ataaaatgac tggagagatt gatttttcat tcgtacctag tgagtttgat gtgattgaaa
     9841 aaggcttgaa acagtctagt cgtagtggca gagggcgtgg ttcaaatcgt cgttcggata
     9901 agaaggaaga caagagaaaa tcaggacgct caaatgataa gcgtaagcat tcacaaaaag
     9961 acaagaagaa aaaaggaaag aaaccttttt acaaggaagt agctaagaaa ggagccaagc
    10021 atggcaaagg gcgagggaaa ggtcgtcgca caaaataaaa aggcacgcca cgactataca
    10081 atcgtagata cgctagaggc agggatggtc ctgactggaa ctgaaatcaa gagtgtacga
    10141 gctgctcgaa ttaatctcaa ggatggcttt gctcaagtga aaaatggaga agtttggctg
    10201 agcaatgttc atatcgcgcc ttacgaagag ggcaatatct ggaaccagga accagaacgt
    10261 cgtcgtaaac tcctgctcca taaaaggcaa attcaaaaat tggaacaaga gaccaaaggg
    10321 acaggaatga ccttagttcc ccttaaggtc tatataaaag atggctacgc taagcttctt
    10381 ttaggacttg ccaaagggaa gcatgactat gacaaacggg agtctatcaa acgtcgtgag
    10441 caaaatcgag atatcgcgcg tgtgatgaaa gctgttaatc agcgataaaa agaggaattg
    10501 aaaatggaaa aattagttgc ctataaacgc atgcctttgt ggaataaaca aacaatgcct
    10561 gaagctgttc agcaaaagca caatacaaaa gttgggactt gggggaaaat tactgtcttg
    10621 aagggagctc tcaagtttat tgaattgaca gaagaagggg aagttctagc tgaacacctc
    10681 tttgaagcag gggcagacaa tccaatggcc caacctcaag cctggcaccg agtggaagct
    10741 gccacagatg atgtggaatg gtacttggaa ttttattgta aacctgagga ttattttgct
    10801 aaaaaataca ataccaatcc tgttcattca gaggtcctag aggccatgga gacagtgaaa
    10861 caagggaaag ctttggattt gggttgtggt caggggcgta attctctttt tctagcccag
    10921 caagattttg atgtgacggc tgtagatcaa aatggactag ctcttgaaat cttgcaaagc
    10981 attgtggagc aggaagattt ggacatgcct gttggccttt acgatatcaa ttcagctagc
    11041 attgaacaag aatatgattt tatcgtttca acagttgttc tcatgtttct acaagcggac
    11101 cgcattccag ctattattca aaatatgcag gagaaaacca gtgttggtgg ttacaacctt
    11161 atcgtttgtg ccatggacac ggaggattat ccttgctcgg ttaacttccc attcaccttt
    11221 aaagaaggag aactggcaga ctattacaag gattgggaat tggttaagta caatgaaaat
    11281 ccaggccatt tgcaccgtcg cgatgagaat ggcaatcgta ttcaactacg ctttgcgacc
    11341 ttactagcta agaaaatcaa gtaaacacac atgaagatta ggaattttcc tgatcttttt
    11401 tcttttttac gaatgatata gaaaaggagg gaattcatgt ttgttgcgag agatgctagg
    11461 ggagaattgg taaatgtgtt agaggataaa cttgagaagc aagcatacac ctgcccagct
    11521 tgtggaggcc agctccattt gcgtcaagga ccaagtgtac ggacgcattt tgcccataaa
    11581 tccttaaaag actgtgattt tttctttgaa aatgaaagtc cagaacacct ggccaataag
    11641 gaatccctct atcactggtt gaaaaaagag acaaaggttc aattagagta cccgctttca
    11701 gaacttaaac agattgcgga tgtatttgta aatggcaatc tagctctaga agttcagtgt
    11761 agtcccttgc ctcagaaagt ccttaaagag cgaagtgagg gatatcgtag tcagggttac
    11821 caagtactgt ggttgctggg tcaaaaactg tggctcaagg agcgtttgac tcgtctacag
    11881 caaggttttc tttatttcag tcaaaacatg ggcttttatg tttgggaatt agacaaggaa
    11941 aaacaagttt taagactcaa atacctgatt taccaggatc tccgcggtaa actccattat
    12001 caaatcaagg aattttccta tggtcaaggt agtttattgg aaatattgcg tcttccctat
    12061 aagagacaaa aaatatctca ttttacagtt tctgaggaca aggacatctg tcgctatatc
    12121 cggcaacaac tttattatca aaatctcttt tggatgaaag aacaagcaga agcctatcaa
    12181 aagggagaaa atatcctgac ttatggactg aaagaatggt atccacaaat tcgaccaata
    12241 gtgggcaaat ttttccagat tgaacaagac ttgactagct attatcagca cttttatacc
    12301 tattaccaaa aaaatcctca aaatgattgg caaaagcttt atccaccagc cttttatcag
    12361 caatatttct tgaaaaatat ggtagaatag aaaggatgga ggaatctaat ggtattacaa
    12421 agaaatgaaa taaatgaaaa agatacatgg gatctatcaa cgatctaccc aactgaccag
    12481 gcttgggaag aagccttaaa agatttaaca gaacaattgg agacagtagc ccagtatgaa
    12541 ggccatctct tggatagtgc ggataaccta ctagaaatca ctgaattttc tcttgaaatg
    12601 gaacgccaga tagagaagct ttacgtttat gctcatatga agaatgacca ggatacacgt
    12661 gaagctaagt atcaagagta ctatgccaag gccatgacac tctacagcca gttagaccaa
    12721 gccttttcat tctatgagcc tgaatttatg gagattagcg aaaagcagta tgctgacttt
    12781 ttagaagctc aaccaaagct gcaggtttat caacactatt ttgacaagct cttgcaaggc
    12841 aaggatcacg ttctctcaca acgtgaagaa gaattattgg ctggagctgg agaaatcttt
    12901 ggttcagcaa gtgaaacctt tgctatcttg gacaatgcgg atattgtgtt cccttatgtc
    12961 ctagacgatg atggtaaaga agttcagcta tctcatggga cttacacacg tttgatggag
    13021 tctaaaaaac gtgaggttcg tcgtggtgcc tatcaagctc tttatgcgac ttacgaacaa
    13081 ttccaacaca cctatgccaa aaccttgcaa accaatgtta aggtgcaaaa ttaccgtgct
    13141 aaagttcgta actacaagag tgctcgtcat gcagccctcg cagcgaattt tgttccagaa
    13201 agtgtttatg acaatttggt agcagcagtt cgcaagcatt tgccactctt acatcgctat
    13261 cttgagcttc gttcaaaaat cttggggatt tcagatctca agatgtacga tgtctacaca
    13321 ccgctttcat ctgttgaata cagttttacc taccaagaag ccttgaaaaa agcagaagat
    13381 gctttggcag tcttgggtga ggattacttg agccgtgtta aacgtgcctt cagcgagcgt
    13441 tggattgatg tttacgaaaa tcaaggcaag cgttcaggtg cctactctgg tggttcttac
    13501 gataccaatg cctttatgct tctcaactgg caggacaatc tggacaatct ctttactctt
    13561 gttcatgaaa caggtcacag tatgcattca agctatactc gtgaaactca gccttatgtt
    13621 tacggagatt actctatctt tttggctgag attgcctcaa ctaccaatga aaatatcttg
    13681 acggagaaat tattggaaga agtggaagac gacgcaacac gctttgctat tctcaataac
    13741 ttcctagatg gtttccgtgg aacagttttc cgccaaactc aatttgctga gtttgaacac
    13801 gccattcacc aagcagatca aaatggggag gtcttgacaa gcgatttcct aaataaactc
    13861 tacgcagact tgaaccaaga gtattatggt ttgagtaagg aagacaatcc tgaaatccaa
    13921 tacgagtggg ctcgtattcc acacttctac tataactact atgtatatca atattcaact
    13981 ggctttgcgg ccgcctcagc cttggctgaa aaaattgtcc atggtagtca agaagaccgt
    14041 gaccgctata tcgactacct caaggcaggt aagtcggact atccacttaa tgtcatgaga
    14101 aaagctggtg ttgatatgga gaaggaagac tacctcaacg atgcctttgc agtctttgaa
    14161 cgccgtttaa atgagtttga agcccttgtt gaaaaattag gattggcata aaatggttga
    14221 atcgtatagt aagaatgcta accataacat gcgtcgtcct gtcgtcaaag aagaaattgt
    14281 agacttgatg cgtcagcgtc aaaagcaggt cacaggtttc ttgaaagaat tggaagactt
    14341 tgcccgcaag gaaaatattc ctattattcc ccatgaaacg gttgcttatt tccgttttct
    14401 tatggaaacc atgcagccta aaaatattct ggaaattggg acggctatcg gtttttcagc
    14461 tctcttgatg gctgaacatg cgccaaatgc taagattaca actattgatc gtaatccaga
    14521 aatgattggt tttgccaagg aaaattttgc ccagtttgac agtcgcaagc aaatcactct
    14581 cctagaggga gatgcggtgg atgtcttatc tacactgaca gagtcttatg atttcgtctt
    14641 tatggattct gccaagtcta aatacatcgt ctttctgcca gaaatcctca aacatttgga
    14701 agttggtggt gtggttgtct tggatgatat ttttcaaggt ggtgatgttg ccaaggatat
    14761 tatggaagtc cgtcgtggtc agcgaaccat ttatcgaggc cttcaaaaat tatttgatgc
    14821 aaccttagac aatccagaac tcaccgcaac attagtgcct ttaggagatg gtattctcat
    14881 gcttcgtaaa aatgtagcag atgttcaact gtctgaaagc gaatgatttt cagaaaaatt
    14941 taagaaaaaa tagtaaaata gatagagtaa cacttatctc aaaggagtag acatgaagaa
    15001 aaaattattg gcaggtgcca tcacactatt atcagtagca actttagcag cttgttcgaa
    15061 agggtcagaa ggggcagacc ttatcagcat gaaaggggat atcatcacag aacatcaatt
    15121 ttatgagcaa gtgaaaaaca acccttcagc ccaacaagtc ttgttaaata tgaccatcca
    15181 aaaagttttt gaaaaacaat atggctcaga gcttgatgat aaagaggttg atgatactat
    15241 tgccgaagaa aaaaaacaat atggcgaaaa ctaccaacgt gtcttgtcac aagcaggtat
    15301 gactcttgaa acacgtaaag ctcaaattcg tacaagtaaa ttagttgagt tggcagttaa
    15361 gaaggtagca gaagctgaat tgacagatga agcctataag aaagcctttg atgagtacac
    15421 tccagatgta acggctcaaa tcatccgtct taataatgaa gataaggcca aagaagttct
    15481 cgaaaaagcc aaggcagaag gtgctgattt tgctcaatta gccaaagata attcaactga
    15541 tgaaaaaaca aaagaaaatg gtggagaaat tacctttgat tctgcttcaa cagaagtacc
    15601 tgagcaagtc aaaaaagccg ctttcgcttt agatgtggat ggtgtttctg atgtgattac
    15661 agcaactggc acacaagcct acagtagcca atattacatt gtaaaactca ctaagaaaac
    15721 agaaaaatca tctaatattg atgactacaa agaaaaatta aaaactgtta tcttgactca
    15781 aaaacaaaat gattcaacat ttgttcaaag cattatcgga aaagaattgc aagcagccaa
    15841 tatcaaggtt aaggaccaag ccttccaaaa tatctttacc caatatatcg gtggtggaga
    15901 ttcaagctca agcagtagta catcaaacga atagtccaaa tcaatgagtc agggaaaaaa
    15961 actcgacttc aggaaaaaat gaagcaaaca ttcccacaat aaaacgcata gtacaaggtt
    16021 tgtactgacc ccaaaagtta gacaattaat ttatctgaag gatttagttc tgtattgcac
    16081 agggctaagt ccttttagtt ttaccttaat tctcttattg ttgtaataat caatatagtc
    16141 tataatggct tgttccaatt gattaagtga tttaaatgtt tgctcatagc cataaaacat
    16201 ttcggatttt aaaatgccaa agaaagattc catcctatcg ttgtcttggc tgtttccttt
    16261 gcgtgacata gatgcttgaa ttcccttact ctctaggaag caatgataag aatcgtgttg
    16321 gtattgccag ccttggtcac tatggagaat cgtattctcg tagtgcttct ctttgaatgc
    16381 ctgttccaac attaacgatc aatcaattta atcatgtacc taatattaga attgtttatc
    16441 ccaaatttat ttgaaagctt c
//
LOCUS       DAVBOD010000048        15418 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 640-05
            SAMEA1012484-rid20186543.denovo.048, whole genome shotgun sequence.
ACCESSION   DAVBOD010000048 DAVBOD010000000
VERSION     DAVBOD010000048.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012484
            Sequence Read Archive: ERR059358
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 15418)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15418)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979948.1
            Genome Coverage       :: 595x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:03:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,266
            CDSs (total)                      :: 2,219
            Genes (coding)                    :: 2,091
            CDSs (with protein)               :: 2,091
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 71 of 128
            Pseudo Genes (incomplete)         :: 50 of 128
            Pseudo Genes (internal stop)      :: 33 of 128
            Pseudo Genes (multiple problems)  :: 22 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15418
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012484-rid20186543.denovo.048"
                     /strain="NIG 640-05"
                     /db_xref="taxon:1313"
     gene            complement(83..1324)
                     /locus_tag="VQ862_001627"
     CDS             complement(83..1324)
                     /locus_tag="VQ862_001627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HET3115943.1"
                     /translation="MKKIFLTLLTVSLLGGVSTAVAQDFTIAAKHAIAVEANTGKILY
                     EKDATQPVEIASITKLITVYLVYEALENGSITLSTPVDISDYPYQLTTNSEASNIPME
                     ARNYTVEELLEATLVSSANSAAIALAEKIAGSEKDFVDMMRAKLLEWGIQDATVVNTT
                     GLNNETLGDNIYPGSKKDEENKLSAYDVAIVARNLIKKYPQVLEITKKPSSTFAGMTI
                     TSTNYMLEGMPAYRGGFDGLKTGTTDKAGESFVGTTVEKGMRVITVVLNADHQDNNPY
                     ARFTATSSLMDYISSTFTLRKIVQQGDAYQDSKAPVQDGKEDTVTAVAPEDIYLIERV
                     GNQSSQSVQFTPDSKAIPAPLEAGTVVGHLTYEDKDLIGQGYITTERPSFEMVADKKI
                     EKAFFLKVWWNQFVRFVNEKL"
     gene            1427..2536
                     /locus_tag="VQ862_001628"
     CDS             1427..2536
                     /locus_tag="VQ862_001628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000489839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HET3115944.1"
                     /translation="MFRRNKLFFWTTEILLLTIIFYLWRQMGSLINPFVSVLNTIMIP
                     FLLGGFLYYLTNPIVTFLNKVCKLNRLLGILITLCTLVWGMVIGVVYLLPILINQLSS
                     LIISSQTIYSRVQDLIIDLSNYPALQNLDVEATIQQLNLSYVDILQNILNSVSNSVGS
                     VLSALISTVLILIMTPVFLVYFLLDGHKFLPMLERTILKRDRLHIAGLLKNLNATIAR
                     YISGVSIDAIIIGCLAYIGYSIIGLKYALVFAIFSGVANLIPYVGPSIGLIPMIIANI
                     FTDPHRLLIAVIYMLVVQQVDGNILYPRIVGSVMKVHPITILVLLLLSSNIYGVVGMI
                     VAVPTYSILKEISKFLSRLYENHKIMKERERELAK"
     gene            3182..3529
                     /gene="ssrA"
                     /locus_tag="VQ862_001629"
     tmRNA           3182..3529
                     /gene="ssrA"
                     /locus_tag="VQ862_001629"
                     /product="transfer-messenger RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00023"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00023"
     gene            complement(3712..3799)
                     /locus_tag="VQ862_001630"
     tRNA            complement(3712..3799)
                     /locus_tag="VQ862_001630"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(3763..3765),aa:Ser,seq:gga)
     gene            3961..4701
                     /locus_tag="VQ862_001631"
     CDS             3961..4701
                     /locus_tag="VQ862_001631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000920650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HET3115945.1"
                     /translation="MLKTERKQLILEELNQHHVVSLEKLVSLLETSESTVRRDLDELE
                     AENKLRRVHGGAELPHSLQEEETIQEKSVKNLQEKKLLAQKAASLIKEKDVIFIDAGT
                     TTAFLIHELVNKNVTVVTNSIHHAAQLVEKQIPTVMVGGNVKTATDASIGGVALNQIN
                     QLHFDRAFIGMNGVDDGYYTTPDMEEGAVKRAILENAKQTYVLVDSSKIGQTCFAKVA
                     PLKRAIVITSQGHELLQVIKEKTEVIEV"
     gene            4698..5609
                     /gene="pfkB"
                     /locus_tag="VQ862_001632"
     CDS             4698..5609
                     /gene="pfkB"
                     /locus_tag="VQ862_001632"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015605104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HET3115946.1"
                     /translation="MIYTVTLNPSIDYIVRLDQVKVGSVNRMDSDDKFAGGKGINVSR
                     VLKRLNIPNTATGFIGGFTGKFITDTLAEEEIETRFVQVAEDTRINVKIKADQETEIN
                     GTGPTVEPVQLEELKAILSSLTAEDTVVFAGSSAKNLGNVIYKDLISLTRQTGAQVVC
                     DFEGQTLIDSLDYQPLLVKPNNHELGAIFGVKLESLDEIEKYARELLAKGAQNVIISM
                     AGDGALLVTSEGAYFAKPIKGTVKNSVGAGDSMVAGFTGEFVKSKDAVEAFKWGVACG
                     TATTFSDDLATAEFIKETYGKVEVEKR"
     gene            5606..7558
                     /locus_tag="VQ862_001633"
     CDS             5606..7558
                     /locus_tag="VQ862_001633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HET3115947.1"
                     /translation="MKIQDLLRKDVMLLDLQATEKTAVIDEMIKNLTEHGYVTDFETF
                     KEGILAREALTSTGLGDGIAMPHSKNAAVKEATVLFAKSNKGVDYESLDGQATDLFFM
                     IAAPEGANDTHLAALAELSQYLMKDGFADKLRQATSADQVIELFDQASEKTEELVQAP
                     ANDSGDFIVAVTACTTGIAHTYMAQEALQKVAAEMGVGIKVETNGASGVGNQLTAEDI
                     RKAKAIIIAADKAVEMDRFDGKPLINRPVADGIRKTEELINLALSGDTEVYRAANGAK
                     AATASNEKQSLGGALYKHLMSGVSQMLPFVIGGGIMIALAFLIDGALGVPNENLGNLG
                     SYHELASMFMKIGGAAFGLMLPVFAGYVAYSIAEKPGLVAGFVAGAIAKEGFAFGKIP
                     YAAGGEATSTLAGVSSGFLGALVGGFIAGALVLAIKKYVKVPRSLEGAKSILLLPLLG
                     TILTGFVMLAVNIPMAAINTAMNDFLGGLGGGSAVLLGIVLGGMMAVDMGGPVNKAAY
                     VFGTGTLAATVSSGGSVAMAAVMAGGMVPPLAIFVATLLFKDKFTKEERNSGLTNIIM
                     GLSFITEGAIPFGAADPARAIPSFILGSAVAGGLVGLTGIKLMAPHGGIFVIALTSNA
                     LLYLVSVLVGAIVSGVVYGYLRKPQA"
     gene            7722..9947
                     /locus_tag="VQ862_001634"
     CDS             7722..9947
                     /locus_tag="VQ862_001634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000908822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HET3115948.1"
                     /translation="MLISLGIAILLIFAAFKLGAAGITLYNLIRLLVGSLAYLAIFGL
                     LIYLFFFKWIRKQEGLLSGFFTIFAGLLLIFEAYLVWKYGLDKSVLKGTMAQVVTDLT
                     GFRTTSFAGGGLIGVALYIPTAFLFSNIGTYFIGSILILVGSLLVSPWSVYDIAEFFS
                     RGFAKWWEGHERRKEERFVKQEEKARQKAEKEARLEQEETEKALLDLPPVDMETGEIL
                     TEEAVQNLPPIPEEKWVEPEIILPQAELKFPEQEDDSDDEDVQVDFSAKEALEYKLPS
                     LQLFAPDKPKDQSKEKKIVRENIKILEATFASFGIKVTVERAEIGPSVTKYEVKPAVG
                     VRVNRISNLSDDLALALAAKDVRIEAPIPGKSLIGIEVPNSDIATVSFRELWEQSQTK
                     AENFLEIPLGKAVNGTARAFDLSKMPHLLVAGSTGSGKSVAVNGIIASILMKARPDQV
                     KFMMVDPKMVELSVYNDIPHLLIPVVTNPRKASKALQKVVDEMENRYELFAKVGVRNI
                     AGFNAKVEEFNSQSEYKQIPLPFIVVIVDELADLMMVASKEVEDAIIRLGQKARAAGI
                     HMILATQRPSVDVISGLIKANVPSRVAFAVSSGTDSRTILDENGAEKLLGRGDMLFKP
                     IDENHPVRLQGSFISDDDVERIVNFIKTQADADYDESFDPGEVSENEGEFSDGDAGGD
                     PLFEEAKSLVIETQKASASMIQRRLSVGFNRATRLMEELEIAGVIGPAEGTKPRKVLQ
                     Q"
     gene            complement(10100..10528)
                     /locus_tag="VQ862_001635"
     CDS             complement(10100..10528)
                     /locus_tag="VQ862_001635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000073932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3115949.1"
                     /translation="MSNYRRTSKPKTEHIKKGFTVFQKTITTIGSILGLITAGITIMN
                     ALDNNNKNTKKEPTTSQTTTFVKEIQKESPQENTTPNKENNTSQEKTQQEETPKSSVK
                     EEKKEDQKTATQDSTTPATSKPATENEKQPNTPTSENNTQ"
     gene            10666..11808
                     /locus_tag="VQ862_001636"
     CDS             10666..11808
                     /locus_tag="VQ862_001636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000638948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HET3115950.1"
                     /translation="MIYFDNSATTRPYPEALETYMQVASKILGNPSSLHRLGDQATRI
                     LDASRQQIADLIGKKSDEIFFTSGGTEGDNWIIKGVAFEKAQFGKHIIVSAIEHPAVK
                     ESALWLKAQGFEVDFAPVDNKGFVDVEALEDLIRPDTTLVSIMAVNNEIGSIQPIEAI
                     SEFLADKPTISFHVDAVQALAKIPTEKYLTERVDFATFSGHKFHGIRGVGFIYIKSGK
                     KITPLLTGGGQERDYRSTTENVAGIAATAKALRLSMEKLDIFRSKTGQMKAVIRQALL
                     DYPDIFVFSDEEDFAPHILTFGIKGVRGEVIVHAFEDYDIFISTTSACSSKAGKPAGT
                     LIAMGVDKDKAQSAVRLSLDLENDMSQVEQFLTKLKLIYNQTRKVR"
     gene            11817..13031
                     /gene="thiI"
                     /locus_tag="VQ862_001637"
     CDS             11817..13031
                     /gene="thiI"
                     /locus_tag="VQ862_001637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001200101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 4-thiouridine(8) synthase ThiI"
                     /protein_id="HET3115951.1"
                     /translation="MQYSEIMIRYGELSTKGKNRMRFINKLRNNISDVLSIYPQVKVT
                     ADRDRAHAYLNGADYTAVAESLKQVFGIQNFSPVYKVEKSVEVLKSAVQEIMQDIYKE
                     GMTFKISSKRSDHTFELDSRELNQTLGGAVFEAIPNVQAQMKSPDINLQVEIREEAAY
                     LSYETVRGAGGLPVGTSGKGMLMLSGGIDSPVAGYLALKRGVDIEAVHFASPPYTSPG
                     ALKKAQDLTRKLTKFGGNIQFIEVPFTEIQEEIKAKAPEAYLMTLTRRFMMRITDRIR
                     EVRNGLVIINGESLGQVASQTLESMKAINAVTNTPIIRPVVTMDKLEIIDIAQEIDTF
                     DISIQPFEDCCTIFAPDRPKTNPKIKNAEQYEARMDVEGLVERAVAGIMITEITPQAE
                     KDEVDDLIDNLL"
     gene            13166..13990
                     /locus_tag="VQ862_001638"
     CDS             13166..13990
                     /locus_tag="VQ862_001638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001076703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase family protein"
                     /protein_id="HET3115952.1"
                     /translation="MNQSYFYLKMKEHKLKVPYTGKERRVRILLPKDYEKDTDRSYPV
                     VYFHDGQNVFNSKESFIGHSWKIIPAIKRNPDISRMIVVAIDNDGMGRMNEYAAWKFQ
                     ESPIPEQQFGGKGVEYAEFVMEVVKPFIKHKTGWFDGMMTTGCSMGAYHALNFFLQHP
                     DVFTKVIALSGVYDARFFVGDYYNDDAIYQNSPVDYIWNQNDGWFIDRYRQAEIVLCT
                     GLGAWEQDGLPSFYKLKEAFDQKQIPAWFAEWGHDVAHDWEWWRKQMPYFLGNLYL"
     gene            14003..15169
                     /locus_tag="VQ862_001639"
     CDS             14003..15169
                     /locus_tag="VQ862_001639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001108652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="HET3115953.1"
                     /translation="MNYLVISPYYPQNFQQFTIELANKGITVLGIGQESYEQLDEPLR
                     NSLTEYFRVDNLENIDEVKRAVAFLFYKHGPIDRIESHNEYWLELDATLREQFNVFGA
                     KPEDLKKTKYKSEMKKLFKKAGVPVVPGAVIKTEADVDQAVKEIGLPMIAKPDNGVGA
                     AATFKLETEDDINHFKQEWDHSTLYFFEKFVTSSEICTFDGLVDKDGKIVFSTTFDYA
                     YTPLDLMIYKMDNSYYVLKDMDPKLRKYGEAIVKEFGMKERFFHIEFFREGDDYITIE
                     YNNRPAGGFTIDVYNFAHSLDLYRGYAAIVAGEEFPASDFETQYCLATSRRANAHYVY
                     SEEDLLAKYSQQFKVKKVMPAAFAELQGDYLYMLTTPSRQEMDQMIADFGQRQE"
BASE COUNT         4489 a         2896 c         3357 g         4676 t
ORIGIN      
        1 acctgcggct agcttcctag tttgttcttt gattttgaag atgaacttgt atcaaaaaat
       61 cgcggtttaa aatcgcgatt ttttataatt tctcgttaac aaagcggaca aactgattcc
      121 accaaacttt taagaagaag gctttttcaa ttttcttgtc tgctaccatt tcgaaactag
      181 ggcgctctgt ggtgatgtaa ccttgaccaa tcaagtcctt gtcttcataa gtcaaatggc
      241 caaccactgt tccagcttca agtggtgctg ggattgcttt ggaatcaggt gtgaattgaa
      301 cagattgaga agattgattc ccaacacgtt cgattagata gatatcctct ggagccactg
      361 cagttactgt atcttctttt ccatcttgta caggggcttt gctatcttga taggcatcgc
      421 cttgttgaac gattttgcga agtgtaaatg tagaagaaat ataatccatt agggaagatg
      481 tagctgtaaa tcgagcgtaa ggattattgt cttgatgatc tgcatttaaa acaactgtga
      541 tgactctcat gcctttttcg acagtagtac caacaaaaga ctctccagcc ttatctgttg
      601 ttcctgtttt tagcccatca aaaccaccac ggtaagcagg cataccttct aacatgtagt
      661 tggttgaagt gattgtcatc ccagcaaaag tagaagaagg ttttttggtg atttctaaga
      721 cttgtgggta ttttttgatg aggttgcgag caacgatagc gacatcataa gcactaagct
      781 tattttcctc atctttttta gaacctgggt aaatgttatc ccctagagtt tcattgttaa
      841 gacctgtcgt attgacaaca gtggcatcct gaattcccca ttccaagagt tttgcccgca
      901 tcatatcgac gaaatctttt tctgagccag caattttctc agctagggca atagcggcgc
      961 tgttggcact agataccaga gttgcttcaa gcaactcttc gacagtataa ttacgggcct
     1021 ccataggaat attactggct tcagaatttg tcgtcaattg ataaggataa tcagaaatat
     1081 ctacaggagt ggagagggta atacttccgt tttccaaagc ttcatagact agataaacag
     1141 taatcaattt tgttatggaa gcaatttcga caggttgcgt tgcatccttc tcatagagaa
     1201 ttttaccagt atttgcctca acagcaatcg catgtttagc ggcaatggta aaatcttgag
     1261 caacagcagt agaaacaccc cctaaaagag agacagttaa caaagttaaa aatatttttt
     1321 tcatagtagt cttattctat cataaagaaa aaaaatattc ttgctttaat aattcatctg
     1381 ttaagctttt tgaaaatatg gtaaaataaa gtgagggagg taactcatgt ttcgtagaaa
     1441 taaattattt ttttggacca cagaaatttt actcttaacc atcatctttt acctatggag
     1501 acagatggga tctttgatta acccttttgt tagcgtgctt aatacaatta tgattccatt
     1561 tttattaggg ggctttcttt attatttgac aaaccctatt gttactttct taaataaagt
     1621 ctgtaaactc aatcgtttgc ttggtatttt aattaccttg tgtactttgg tctggggaat
     1681 ggtcataggt gttgtctatc tcttacctat tttgattaat cagttatcta gtttgattat
     1741 atctagtcaa actatttata gtcgagtaca agacttaatc atagacttat ctaattatcc
     1801 tgcgctccag aatttggatg tagaagctac aattcagcag ttaaacttat cctatgttga
     1861 tattcttcaa aatatcctaa atagcgtatc aaatagtgtg gggagcgtct tgtcagctct
     1921 tatcagtact gttttgattt tgattatgac tccagttttt ttggtttatt tcttattaga
     1981 tggacataaa ttcttgccca tgcttgaaag aacgattcta aagagggatc gcttgcatat
     2041 tgcaggctta ttaaagaatt taaatgcgac gattgctcgc tatattagtg gagtttcgat
     2101 tgacgcaatc attataggtt gtttggctta tattggctat agtattattg gtttaaaata
     2161 tgctttagtt tttgccattt tttctggtgt agccaattta attccttatg tggggccaag
     2221 tattggtttg attcctatga tcatcgcaaa tatattcact gatccccata gactgctgat
     2281 tgcagtgatt tatatgcttg ttgttcagca ggtagatggc aatatcttat atcctcgaat
     2341 tgtaggaagt gttatgaagg ttcatccaat cacgatttta gttttacttt tgttgtcaag
     2401 caatatctat ggtgtagttg gaatgattgt cgcagtgcca acctattcta tcttgaaaga
     2461 aatttctaag ttcttatccc gtttgtatga aaatcataaa ataatgaaag aacgagaaag
     2521 agaattagct aagtaaaagt caggagaacc ctgatttttc tttactggaa gtggccttta
     2581 gattagaaga ctgaaaataa gttaaagtct taaactaatt ttcacagcta agaatagtag
     2641 aagttaatct gataaaaatc gaaaaaacca gtggaattcc gtgtcagggt aagttccact
     2701 ggttttcata gtctattaaa gttcgaatga aacctattta tagtatattg aaactagaat
     2761 agtacacctc taattctaaa acattgttag aaatcgattt gactgtcctg atctattcgt
     2821 cctattctta tttcatttta ctatattttg gtgcaataag tgaaaagtag tccgaataat
     2881 ataaggattg attttatagt ttttaaactc aaatgaatta aaataaagag agtacgaaaa
     2941 ttctcatctg aaagtatttt agaataattc tcttcgtgaa tttcttcaaa acagatagct
     3001 tcatcttagg tatgtgttaa ttggatttcg taagctctat ttacaatcgt aaagttatgc
     3061 actgaaaaag ttgtagttag tcttccagtt tgctaaattt ctcgaatagt atctttttta
     3121 ggtatgtgat ttctttttgc atttttgagt tagataaggt ataatggttt tattgtcttt
     3181 tggggtcgtt acggattcga caggcattat gaggcatatt ttgcgactcg tgtggcgacg
     3241 taaacgctca gttaaatata actgcaaaaa ataacacttc ttacgctcta gctgcctaaa
     3301 aaccagcagg cgtgacccga tttggattgc tcgtgttcaa tgacaggtct tattattagc
     3361 gagatacgat taagccttgt ctagcggctt gataagagat tgatagactc gcagtttcta
     3421 gacttgagtt atgtgtcgag gggctgttaa aataatacat aacctatggt tgtagacaaa
     3481 tatgttggca ggtgtttgga cgtgggttcg actcccaccg gctccattat tcctttgcat
     3541 tcttttgcat tccttggtaa aacgttgtta aatcaacgtt ttttattttt atctttggta
     3601 ttcctttgca ttcttttgct aaaaagggag tcacaaacag accctatttt aaaaaaagga
     3661 tagaaaaaag gatacaacat ttgtcgcatc ctaaaaataa tcttttttcg acggaagaca
     3721 tgggattcga acccacgcac gctattacac gcctaccgcg tttccaacac ggcctcttaa
     3781 gcctcttgag taatcttcca atacttactc aaatagtcta ccataaaggc tcttatcttg
     3841 caataaaaat tctagaaata agaaaaatga tagattttga aagaaaatga taaaaaatgc
     3901 ttgacttcaa aagaaagtat gatagaatga atagtgtaaa cgataacagg aggtgattcg
     3961 gtgttaaaaa cagagcggaa gcaactgatt ttagaggagt taaatcaaca tcatgtagtt
     4021 tctctagaaa aattagttag tttgctagaa acgtcagaat caacggttcg aagagacttg
     4081 gatgagttgg aagcggaaaa caagcttcgt cgtgtgcatg gtggagcaga actcccccac
     4141 tccttacagg aagaagaaac cattcaagaa aaatcggtca aaaaccttca agaaaagaag
     4201 ttgctggctc agaaagcagc ctctctcatt aaagaaaaag atgtcatctt tatcgatgct
     4261 ggaacaacaa ctgctttttt gattcatgaa ttggtcaata agaatgttac agttgtgacc
     4321 aactccattc accatgccgc tcagttggtt gaaaagcaga ttccaactgt catggttgga
     4381 ggaaacgtca agacggcgac agatgctagt atcgggggcg ttgctcttaa ccagattaac
     4441 caattgcact ttgaccgtgc ctttatcgga atgaatggtg ttgacgatgg ctattatacg
     4501 actcctgata tggaggaggg agctgtgaaa agagctattt tggagaatgc caagcagacc
     4561 tacgtcttgg tggattcgtc aaaaattgga caaacttgct ttgccaaggt agcaccactc
     4621 aaacgcgcta tcgttatcac tagtcaaggg catgagctct tgcaggttat taaggagaaa
     4681 acggaggtaa tagaagtatg atttatacag tcacactcaa tccatccatt gactatatcg
     4741 ttcgtttgga ccaagtcaaa gttggtagtg taaatcgtat ggacagtgat gataagtttg
     4801 ctggtgggaa aggaatcaat gtcagccgtg tcttgaaacg tttgaatata ccaaatacag
     4861 cgacgggatt tatcggtggc tttactggta aatttatcac agatacttta gcagaggaag
     4921 aaatcgagac acgttttgtc caggtggcag aagatactcg tatcaatgtt aaaatcaaag
     4981 cagaccaaga aacagaaatc aacggaacgg gtccaactgt tgaaccggtt cagctagaag
     5041 aattgaaagc tattttatct agtctgacag cagaagatac agttgtcttt gcaggttcaa
     5101 gtgctaaaaa tctaggcaat gttatctata aggatttgat ttccttgacg cgccagactg
     5161 gtgcgcaagt ggtctgtgac tttgaaggac agaccttaat tgatagtttg gactaccagc
     5221 ctcttcttgt aaaaccaaac aatcatgaac ttggagcgat ttttggggtt aaactcgaaa
     5281 gtttagatga aattgagaaa tacgctcgtg agttactggc taagggtgct caaaatgtta
     5341 ttatctctat ggctggtgat ggcgcccttc ttgtcacatc tgagggagct tacttcgcta
     5401 aaccaatcaa aggaacagtc aaaaattcag ttggagctgg tgattctatg gttgctggat
     5461 tcacaggtga atttgtcaaa tcaaaagacg cagtagaagc cttcaaatgg ggagtggctt
     5521 gcggaacggc aactaccttc tcagatgact tggcaacggc ggaatttatt aaagaaacat
     5581 atggaaaagt tgaggtagaa aaaagatgaa aattcaagac ctattgagaa aagatgtcat
     5641 gttgctagat ttgcaggcaa ctgaaaaaac agctgtcatc gacgagatga ttaaaaattt
     5701 gacagagcac ggttatgtaa cagattttga aacatttaaa gaaggaattt tggcgcgtga
     5761 agctttgact tctactggtt tgggtgatgg aatcgcaatg cctcacagca aaaacgctgc
     5821 tgtcaaagaa gcgacagttc tatttgctaa gtcaaataag ggtgttgact acgagagctt
     5881 ggatggacaa gcaactgacc tcttcttcat gattgcagct ccagaaggtg ccaatgatac
     5941 tcacttggca gccttggcag aattgtctca atacttgatg aaagacggtt ttgcagacaa
     6001 acttcgtcaa gcaacatctg cagaccaagt tatcgaactt tttgaccaag cttcagaaaa
     6061 aactgaggaa cttgttcaag cacctgctaa tgactctggt gactttatcg tagctgttac
     6121 agcttgtaca acaggtattg cccacactta catggcccaa gaagcccttc aaaaagtagc
     6181 tgctgaaatg ggggttggta tcaaggtcga aaccaacggt gctagcggtg ttggaaatca
     6241 actaactgca gaagatatcc gtaaggctaa agctattatc attgcagcag acaaggccgt
     6301 tgaaatggat cgatttgatg gaaaaccatt gatcaatcgt ccagttgctg acggtatccg
     6361 taagacagaa gagctaatta acttggctct ttcaggagat actgaagtct accgtgccgc
     6421 taatggtgcc aaagctgcaa cagcctctaa cgaaaaacaa agccttggtg gtgccttgta
     6481 caaacacttg atgagtggtg tatctcaaat gttaccattc gttatcggtg gtggtatcat
     6541 gattgccctt gccttcttga ttgacggtgc tttgggtgtt ccaaatgaaa accttggcaa
     6601 tcttggttct taccatgagt tagcttctat gttcatgaaa attggtggag ctgcctttgg
     6661 tttgatgctt ccagtctttg cgggttatgt tgcctactct attgctgaaa aaccgggttt
     6721 ggtagcaggt ttcgtggctg gtgctattgc caaagaaggt tttgcctttg gtaaaattcc
     6781 ttatgccgca ggtggtgaag caacttcaac tcttgcaggt gtctcatctg gtttcctagg
     6841 tgcccttgtt ggtggattta tcgcaggtgc cttggttctt gccatcaaga aatacgttaa
     6901 agttcctcgt tcactcgaag gtgctaaatc aatccttcta ttgccacttc ttggaacaat
     6961 cttgacagga tttgttatgc tagctgtgaa tatcccaatg gctgcaatca acactgctat
     7021 gaatgacttc ctaggcggtc ttggaggagg ttcagctgtc cttcttggta tcgtccttgg
     7081 tggaatgatg gctgttgaca tgggtggacc agttaataaa gcagcttatg tctttggtac
     7141 aggtacgctt gcagcaactg tttcttcagg tggttctgta gccatggcag cagttatggc
     7201 tggaggaatg gtgccaccac ttgcaatctt tgtcgcaact cttcttttca aagataaatt
     7261 tactaaggaa gaacgtaact ctggtttgac aaacatcatc atgggcttgt catttatcac
     7321 tgagggagcg attccatttg gtgccgctga cccagctcgt gcgattccaa gcttcatcct
     7381 tggttcagca gtagcaggtg gactcgttgg tcttactggt atcaaactca tggcgccaca
     7441 cggaggaatc ttcgttatcg cccttacttc aaatgctctc ctttacctcg tttctgtctt
     7501 ggtaggagca atcgtaagtg gtgtggttta tggttaccta cgcaaaccac aagcataaaa
     7561 aatagaaaaa tgaaaagatt ggaccgtttg gtgcagtctt tttctcttcc cgaaatgcct
     7621 gtgaaatatg gtataataga agaatggcaa acaagaatac aagtacaaca agacggagac
     7681 cgtctaaagc agaactggaa agaaaagaag cgattcaacg aatgttgatt tcgttaggaa
     7741 ttgcgatttt attgattttc gcagccttca aattaggggc tgcaggtata accctttata
     7801 atttaattcg cttgctagtg ggtagcctag cttatctggc gatattcggc ctattaatct
     7861 atctcttctt tttcaagtgg atacgaaaac aggaaggact cttatctggc tttttcacca
     7921 tatttgctgg cttactcttg atttttgagg cctacttggt ttggaaatat ggtttggaca
     7981 agtccgttct aaaagggacc atggctcagg ttgtgacaga tctgactggt tttcgaacga
     8041 ctagctttgc tggagggggc ttgatcgggg tcgctcttta tattccaaca gcctttctct
     8101 tttcaaatat cggaacttac tttattggtt ctatcttgat tttagtgggt tctctcctag
     8161 tcagcccttg gtctgtttac gatattgctg aatttttcag tagaggcttt gccaaatggt
     8221 gggaagggca cgagcgtcga aaagaggaac gctttgtcaa acaagaagaa aaagctcgcc
     8281 aaaaggctga gaaagaggct agattagaac aagaagagac tgaaaaagcc ttactcgatt
     8341 tgcctcctgt tgatatggaa acgggtgaaa ttctgacaga ggaagctgtt caaaatcttc
     8401 cacctattcc agaagaaaag tgggtggaac cagaaatcat cctgcctcaa gctgaactta
     8461 aattccctga acaggaagat gactcagatg acgaagatgt tcaggtcgat ttttcagcca
     8521 aagaagccct tgaatacaaa cttccaagct tacaactctt tgcaccagat aaaccaaaag
     8581 atcagtctaa agagaagaaa attgtcagag aaaatatcaa aatcttagaa gcaacctttg
     8641 ctagctttgg tattaaggta acagttgaac gggccgaaat tgggccatca gtgaccaagt
     8701 atgaagtcaa gccggctgtt ggtgtaaggg tcaaccgcat ttccaatcta tcagatgacc
     8761 tcgctctagc cttggctgcc aaagatgtcc ggattgaagc accaatccct gggaaatccc
     8821 taatcggaat tgaagtgccc aactccgata ttgccactgt atctttccga gaactatggg
     8881 aacaatcgca aacgaaagca gaaaatttct tggaaattcc tttagggaag gctgttaatg
     8941 gaaccgcaag agcttttgac ctttctaaaa tgccccactt gctagttgca ggttcaacgg
     9001 gttcagggaa gtcagtagca gttaacggca ttattgctag cattctcatg aaggcgagac
     9061 cagatcaagt taaatttatg atggtcgatc ccaagatggt tgagttatct gtttacaatg
     9121 atattcccca cctcttgatt ccagtcgtga ccaatccacg caaagccagc aaggctctgc
     9181 aaaaggttgt ggatgaaatg gaaaaccgtt atgaactctt tgccaaggtg ggagttcgga
     9241 atattgcagg ttttaatgcc aaggtagaag agttcaattc ccagtctgag tacaagcaaa
     9301 ttccgctacc attcattgtc gtgattgtgg atgagttggc tgacctcatg atggtggcca
     9361 gcaaggaagt ggaagatgct atcatccgtc ttgggcagaa ggcgcgtgct gcaggtatcc
     9421 acatgattct tgcaactcag cgtccatctg ttgatgtcat ctctggtttg attaaggcca
     9481 atgttccatc tcgtgtagca tttgcggttt catcaggaac agactcccgt acgattttgg
     9541 atgaaaatgg agcagaaaaa cttcttggtc gaggagacat gctctttaaa ccgattgatg
     9601 aaaatcatcc agttcgtctc caaggctcct ttatctcgga tgacgatgtt gagcgcattg
     9661 tgaacttcat caagactcag gcagatgcag actacgatga gagttttgat ccaggtgagg
     9721 tttctgaaaa tgaaggagaa ttttcggatg gagatgctgg tggtgatccg ctttttgaag
     9781 aagctaagtc tttggttatc gaaacacaga aagccagtgc gtctatgatt cagcgtcgtt
     9841 tatcagttgg atttaaccgt gcgacccgtc tcatggaaga actggagata gcaggtgtca
     9901 tcggtccagc tgaaggtacc aaacctcgaa aagtgttaca acaataaaaa aatagcttct
     9961 ttccaagttt ggagggaagc tatttttctg gctattgatt acttttatac tcttcgcaaa
    10021 tctcttcaaa ccacgtcagc ttcgccttgc cgtactcaag tactgtctac ggctagcttc
    10081 ctagtttgct ctttgatttt cattgagtat tattttctga agttggagta ttgggctgtt
    10141 tttcattttc agtggcaggt ttacttgtag caggtgtagt agagtcctga gttgctgttt
    10201 tctgatcttc ttttttctct tccttgacgc tagattttgg cgtttcttct tgttgtgttt
    10261 tttcttgaga agtgttattt tccttatttg gagtagtatt ttcctgaggg gattcttttt
    10321 gaatttcttt gacaaaggtt gtcgtctggc ttgtcgtagg ttctttttta gtatttttat
    10381 tattattatc caaggcgttc atgatcgtga tacccgcggt aatcaaacca aggatactac
    10441 cgatagtagt aatggttttt tgaaaaacag taaagccttt tttgatatgt tctgttttcg
    10501 gttttgaagt tctacgatag ttagacatac attctctcct ttgattatga tttattatac
    10561 tctgtttctt taaaaaaatc ttaaaaaaag agaaattgcc ctttcttgtc gcaggctccg
    10621 tttcatgata caatagaagg agtgatttta gaaagcgtga gaaacatgat ttactttgat
    10681 aattcggcga cgaccaggcc ctatccagaa gcccttgaaa cctatatgca ggtggcttca
    10741 aaaattttag gaaatccatc tagtctccat cgtttgggag accaggcaac acgaatttta
    10801 gatgcttccc gtcaacagat tgcagattta atcggtaaga aaagtgatga aatcttcttt
    10861 acatctggtg ggacagaagg ggataactgg atcatcaagg gagtagcatt tgaaaaagcc
    10921 cagtttggca agcacatcat cgtatcagcc attgaacatc cagcagttaa ggaatcagcc
    10981 ctctggttga aagctcaagg ttttgaagtg gattttgctc cagttgataa caaaggattt
    11041 gtggatgttg aggcgctaga agatttgata agacctgata cgaccctcgt ttccatcatg
    11101 gctgtgaaca atgaaatcgg ctctatccaa cctattgagg ctatttcaga attcttggca
    11161 gacaagccaa ctatttcctt ccacgttgat gcggttcagg cgcttgccaa gattccgact
    11221 gaaaagtatc tgacagaacg agtggatttc gcgactttct ctggtcacaa gttccacgga
    11281 atccgtggtg ttggttttat ctatatcaag tctggcaaga agattacgcc tcttttaaca
    11341 ggtggtggtc aggaacgtga ttaccgttcg acaactgaaa atgtggcagg aattgcagcg
    11401 accgctaagg ctctccgttt atctatggaa aagctagata tctttaggag caagactggg
    11461 cagatgaagg cagtgattcg tcaagcactt ctggactatc cggatatatt tgtcttttca
    11521 gatgaggaag acttcgcccc tcatattctg acttttggaa tcaagggtgt tcgtggtgag
    11581 gtcattgttc acgcctttga agactatgat attttcatct caacgacctc ggcttgttcg
    11641 tccaaggctg ggaaaccagc cggaaccctg attgctatgg gagtggacaa ggataaggct
    11701 cagtcagctg tgcgtcttag tctagacctt gaaaatgata tgagtcaggt cgagcagttc
    11761 ttgaccaagc taaaattaat ttacaatcaa actagaaaag taagatagga gcattcatgc
    11821 agtattcaga aattatgatt cgctacggtg agctgtcaac caagggcaaa aatcgtatgc
    11881 gtttcatcaa taaacttcgc aataatattt cagacgtttt gtctatctat ccccaagtta
    11941 aggtaacagc agatcgcgac cgtgcccacg cttacctcaa tggagcagat tacacagcag
    12001 tagcagaatc gctcaaacaa gtatttggaa ttcaaaactt ttcccctgtt tataaggttg
    12061 aaaaatctgt agaagttctg aagtctgctg tccaagagat tatgcaggac atctacaagg
    12121 aaggcatgac ctttaaaatc tctagcaagc gtagcgacca cacctttgaa ttggacagtc
    12181 gtgaactcaa ccaaacgctt ggaggggctg tattcgaagc cattccaaac gtacaagctc
    12241 aaatgaaaag tcctgacatc aatcttcagg tggagatacg tgaagaagca gcctatcttt
    12301 cttatgaaac cgttcgaggg gcaggtggat taccagtggg aacttctggt aagggcatgc
    12361 tcatgttgtc agggggaatc gattcccctg tagctggcta tctagcgctt aaacgagggg
    12421 tagatataga ggcagttcac tttgccagcc caccttacac gagtcctggt gctcttaaaa
    12481 aagcccaaga tttgacccgt aaattaacca aatttggggg aaatatccag tttatcgaag
    12541 ttccttttac agagattcaa gaggaaatca aagccaaagc gccagaagcc taccttatga
    12601 ccttgacgcg tcgttttatg atgcgtatta ctgaccgtat tcgtgaggta cgaaatggtt
    12661 tagttatcat caatggggaa agtctaggtc aagtagccag ccaaaccctt gaaagtatga
    12721 aggctatcaa tgctgttacc aacactccca tcattcgtcc tgtggttacc atggacaagt
    12781 tggaaatcat tgacatcgcc caggaaatcg atacctttga catttcaatc caaccgtttg
    12841 aagactgttg tactattttt gcaccagatc gtccaaaaac aaatcctaaa attaagaatg
    12901 cggagcagta cgaagcgcgt atggatgttg aaggcttggt tgagcgagca gtggctggaa
    12961 tcatgattac tgaaatcaca cctcaagccg aaaaagatga agttgatgac ttgattgaca
    13021 atctgctcta attcagaaaa tccaaaagaa tagcgaaaat cagtaaaaaa agttagtttt
    13081 ttctctaaaa acaggtaaaa aactaacttt ttttattttt atgatataat gatataaaat
    13141 tttgaatata gagagttttc tgacaatgaa tcaatcctac ttttatctaa aaatgaaaga
    13201 acacaaactc aaggttcctt atacaggtaa ggagcgccgt gtacgtattc ttcttcctaa
    13261 agattatgag aaagatacag accgttccta tcctgttgta tactttcatg acgggcaaaa
    13321 tgtttttaat agcaaagagt ctttcattgg acattcatgg aagattatcc cagctatcaa
    13381 acgaaatccg gatatcagtc gcatgattgt cgttgctatt gacaatgatg gtatggggag
    13441 gatgaatgag tatgcggctt ggaagttcca agaatctcct atcccagagc agcagtttgg
    13501 tggtaagggt gtggagtatg ctgagtttgt catggaggtg gtcaagcctt ttatcaagca
    13561 caaaacaggt tggtttgatg gcatgatgac gacaggttgc tctatgggag cctatcatgc
    13621 actcaatttc ttcctccagc atccagatgt ctttaccaaa gtgattgctc tcagtggtgt
    13681 ttacgacgca cgtttctttg tcggcgatta ctacaacgat gatgctattt accaaaactc
    13741 gccagtagat tatatttgga accaaaacga tggctggttt attgaccgtt accgtcaggc
    13801 agagattgtg ctgtgtacgg ggcttggagc ctgggaacaa gatggtttac catcctttta
    13861 caagctcaaa gaagcctttg accagaaaca aattccagcc tggtttgctg aatggggaca
    13921 tgatgtcgcc cacgactggg aatggtggcg taaacaaatg ccttatttcc tcggtaatct
    13981 ctatttataa aaggagttac ctatgaatta ccttgttatt tctccctact atccacaaaa
    14041 ctttcaacag tttaccatcg aactagctaa taaaggcatc acagtcttgg gaattggtca
    14101 agagtcttac gagcaattgg atgagccctt gcgcaatagc ttgaccgagt attttcgtgt
    14161 tgataatctt gagaacatag atgaagtcaa acgtgcagtt gcttttctct tttataaaca
    14221 tggtccaatt gaccgcatcg agtctcacaa tgaatactgg cttgagctag acgcaacact
    14281 cagagaacaa ttcaatgttt ttggtgccaa accagaggat ctcaaaaaga cgaaatataa
    14341 gtctgaaatg aagaaacttt tcaaaaaagc aggtgttcct gtggtacctg gagctgttat
    14401 caagacggaa gcagatgttg atcaagcagt gaaagaaatc ggtcttccaa tgattgccaa
    14461 acctgataat ggagtgggag cagccgcaac ctttaaactt gagacagaag acgatatcaa
    14521 tcacttcaag caagaatggg accattcaac cctttatttc tttgaaaaat ttgtcacttc
    14581 cagcgaaatc tgtacctttg acgggctcgt ggacaaggat ggaaagattg tcttctcaac
    14641 aacctttgac tacgcctata caccgcttga cctcatgatt tataagatgg acaattctta
    14701 ttatgtgctc aaggatatgg atcctaaact gcgcaagtat ggggaagcaa ttgtcaaaga
    14761 atttggtatg aaagaacggt ttttccatat tgagttcttc cgtgaggggg acgattatat
    14821 taccatcgag tacaataacc gccctgcagg tggttttacc attgatgttt ataactttgc
    14881 tcattccttg gacctttatc gtggctatgc agctattgtc gcaggagagg agttcccggc
    14941 gtcagacttt gaaactcagt attgtttggc tacttctcgc cgtgcaaatg ctcactatgt
    15001 ttattcagaa gaggatttgc ttgccaaata tagccagcag ttcaaggtta aaaaagtcat
    15061 gccagctgcc ttcgcggaac ttcaaggaga ttacctgtat atgctgacaa ctccgagtcg
    15121 acaagaaatg gatcagatga ttgctgattt cggacaacgt caagaataag aactatcgga
    15181 ttaaggaaat tcactccctt aatccttttg ttttgtctgg taaaaaataa gagcatccta
    15241 acaaggtagc tatcataaaa cttgttcgat aactatttga agcaggatta ggtggctaga
    15301 aattgaattt taacatttca atttagtcat agtattgtgt tttcgtatcc ttaaatcagc
    15361 taaaaggatc catgacgaca cctatacgat atagttttca ggataccaaa ccagtcta
//
LOCUS       DAVBOD010000049        14180 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 640-05
            SAMEA1012484-rid20186543.denovo.049, whole genome shotgun sequence.
ACCESSION   DAVBOD010000049 DAVBOD010000000
VERSION     DAVBOD010000049.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012484
            Sequence Read Archive: ERR059358
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 14180)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14180)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979948.1
            Genome Coverage       :: 595x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:03:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,266
            CDSs (total)                      :: 2,219
            Genes (coding)                    :: 2,091
            CDSs (with protein)               :: 2,091
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 71 of 128
            Pseudo Genes (incomplete)         :: 50 of 128
            Pseudo Genes (internal stop)      :: 33 of 128
            Pseudo Genes (multiple problems)  :: 22 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14180
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012484-rid20186543.denovo.049"
                     /strain="NIG 640-05"
                     /db_xref="taxon:1313"
     gene            <1..183
                     /locus_tag="VQ862_001640"
     CDS             <1..183
                     /locus_tag="VQ862_001640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET3115954.1"
                     /translation="LTVEDQAYNHALSKERSKVENIFAKVKTFKMFSTTYRNHRKRFG
                     LRMNLIAGIINHELGF"
     gene            complement(498..2189)
                     /locus_tag="VQ862_001641"
     CDS             complement(498..2189)
                     /locus_tag="VQ862_001641"
                     /EC_number="6.1.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine--tRNA ligase"
                     /protein_id="HET3115955.1"
                     /translation="MNTKELIASELASIIDSLDQEAILKLLETPKNSEMGDIAFPAFS
                     LAKVERKAPQMIAAELAEKMNSQAFEKVVATGPYVNFFLDKSAISAQVLQAVTTEKEH
                     YADQNIGKQENVVIDMSSPNIAKPFSIGHLRSTVIGDSLSHIFQKIGYQTVKVNHLGD
                     WGKQFGMLIVAYKKWGDEEAVKAHPIDELLKLYVRINAEAENDPSLDEEAREWFRKLE
                     NGDEEALALWQWFRDESLVEFNRLYNELKVEFDSYNGEAFYNDKMDAVVDILSEKGLL
                     LESEGAQVVNLEKYGIEHPALIKKSDGATLYITRDLAAALYRKNEYQFAKSIYVVGQE
                     QSAHFKQLKAVLQEMGYDWSDDITHVPFGLVTKEGKKLSTRKGNVILLEPTVAEAVSR
                     AKVQIEAKNPELENKDQVAHAVGVGAIKFYDLKTDRTNGYDFDLEAMVSFEGETGPYV
                     QYAYARIQSILRKADFKPETAGNYSLNDTESWEIIKLIQDFPRIINRAADNFEPSIIA
                     KFAISLAQSFNKYYAHTRILDESPERDSRLALSYATAVVLKEALRLLGVEAPEKM"
     gene            2325..2771
                     /gene="argR"
                     /locus_tag="VQ862_001642"
     CDS             2325..2771
                     /gene="argR"
                     /locus_tag="VQ862_001642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HET3115956.1"
                     /translation="MRKRDRHQLIKKMITEEKLSTQKEIQDRLEAHNVCVTQTTLSRD
                     LREIGLTKVKKNDMVYYVLVNETEKIDLVEFLSHHLEGVARAEFTLVLHTKLGEASVL
                     ANIVDVNKDKWILGTVAGANTLLVICRDQHVAKLMEDRLLDLMKDK"
     gene            2822..5356
                     /gene="mutS"
                     /locus_tag="VQ862_001643"
     CDS             2822..5356
                     /gene="mutS"
                     /locus_tag="VQ862_001643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HET3115957.1"
                     /translation="MAIEKLSPGMQQYVDIKKQYPDAFLLFRMGDFYELFYEDAVNAA
                     QILEISLTSRNKNADNPIPMAGVPYHSAQQYIDVLIEQGYKVAIAEQMEDPKQAVGVV
                     KREVVQVITPGTVVDSSKPDSQNNFLVSIDREGNQFGLAYMDLVTGDFYVTGLLDFTL
                     VCGEIRNLKAREVVLGYDLSEEEEQILSRQMNLVLSYEKESFEDLHLLDLRLATVEQT
                     ASSKLLQYVHRTQMRELNHLKPVIRYEIKDFLQMDYATKASLDLVENARSGKKQGSLF
                     WLLDETKTAMGMRLLRSWIHRPLIDKERIVQRQEVVQVFLDHFFERSDLTDSLKGVYD
                     IERLASRVSFGKTNPKDLLQLATTLSSVPRIRAILEGMEQPTLAYLIAQLDAIPELES
                     LISAAIAPEAPHVITDGGIIRTGFDETLDKYRCVLREGTSWIAEIEAKERENSGISTL
                     KIDYNKKDGYYFHVTNSQLGNVPAHFFRKATLKNSERFGTEELARIEGDMLEAREKSA
                     NLEYEIFMRIREEVGKYIQRLQALAQGIATVDVLQSLAVVAETQHLIRPEFGDDSQID
                     IRKGRHAVVEKVMGAQTYIPNTIQMAEDTSIQLVTGPNMSGKSTYMRQLAMTAVMAQL
                     GSYVPAESAHLPIFDAIFTRIGAADDLVSGQSTFMVEMMEANNAISHATKNSLILFDE
                     LGRGTATYDGMALAQSIIEYIHEHIGAKTLFATHYHELTSLESSLQHLVNVHVATLEQ
                     DGQVTFLHKIEPGPADKSYGIHVAKIAGLPADLLARADKILTQLENQGTESPPPMRQT
                     SAVTEQISLFDRAEEHPILAELAKLDVYNMTPMQVMNVLVELKQKL"
     gene            5503..7197
                     /gene="patA"
                     /locus_tag="VQ862_001644"
     CDS             5503..7197
                     /gene="patA"
                     /locus_tag="VQ862_001644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000908145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit PatA"
                     /protein_id="HET3115958.1"
                     /translation="MLIQKIKTYKWQALASLLMTGLMVASSLLQPRYLQEVLGALLTG
                     KYEAIYSIGAWLIGVAVVGLVAGGLNVVLAAYIAQGVSSDLREDAFRKIQTFSYADIE
                     QFNAGNLVVRMTNDINQIQNVVMMTFQILFRLPLLFIGSFILAVQTLPSLWWVIVLMV
                     VLIFGLTAVMMGMMGPRFAKFQTLLERINAIAKENLRGVRVVKSFVQEKEQFAKFTEV
                     SDELLGQNLYIGYAFSVVEPFMMLVGYGAVFLSIWLVAGMVQSDPSVVGSIASFVNYL
                     SQIIFTIVMVGFLGNSVSRAMISMRRIREILDAEPAMTFKDIPDEELVGSLSFENVTF
                     TYPMDNEPMLKDVSFTIEPGQMVGVVGATGAGKSTLAQLIPRLFDPQNGAIKIGGKDI
                     REVSEGTLRKTVSIVLQRAILFSGTIADNLRQGKGNATLFEMERAANIAQASEFIHRM
                     EKTFESPVEERGTNFSGGQKQRMSIARGIVSNPRILIFDDSTSALDAKSERLVQEALN
                     KDLKGTTTIIIAQKISSVVHADKILVLNQGRLIGQGTHADLVANNAVYREIYETQK"
     gene            complement(7527..7790)
                     /locus_tag="VQ862_001645"
                     /pseudo
     CDS             complement(7527..7790)
                     /locus_tag="VQ862_001645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199219.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
     gene            7988..9754
                     /gene="patB"
                     /locus_tag="VQ862_001646"
     CDS             7988..9754
                     /gene="patB"
                     /locus_tag="VQ862_001646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000859866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit PatB"
                     /protein_id="HET3115959.1"
                     /translation="MKTVQFFWHYFKVYKFSFVVVILMIVLATFAQALFPVFSGQAVT
                     QLANLVQAYQNGNPELVWQSLSGIMVNLGLLVLVLFISSVIYMCLMTRVIAESTNEMR
                     KGLFGKLAQLTVSFFDRRQDGDILSHFTSDLDNILQAFNESLIQVMSNIVLYIGLILV
                     MFSRNVTLALITIASTPLAFLMLIFIVKMARKYTNLQQKEVGKLNAYMDESISGQKAV
                     IVQGIQEDMMAGFLEQNERVRKATFKGRMFSGILFPVMNGMSLINTAIVIFAGSAVLL
                     NDKSIETSTALGLIVMFAQFSQQYYQPIIQVAASWGSLQLAFTGAERIQEMFDAEEEI
                     RPEKAPTFTKLQESVEISHIDFSYLPDKPILKDVSISAPKGQMTAVVGPTGSGKTTIM
                     NLINRFYDVDAGGIYFDGKDIRGYDLDSLRSKVGIVLQDSVLFSGTIRDNIRFGVPDA
                     SQEMVEVAAKATHIHDYIESLPDKYDTLIDDDQSIFSTGQKQLISIARTLMTDPEVLI
                     LDEATSNVDTVTESKIQHAMEVVVAGRTSFVIAHRLKTILNADQIIVLKDGEVIERGN
                     HHELLKLGGFYSELYHNQFVFE"
     gene            9893..10582
                     /locus_tag="VQ862_001647"
     CDS             9893..10582
                     /locus_tag="VQ862_001647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HET3115960.1"
                     /translation="MARTVVGVAANLCPVDAEGKIIHSSVSCRFAEIIRQVGGLPLVI
                     PVGDESVVRDYVEMIDKLILTGGQNVHPQFYGEKKTVESDDYNLVRDEFELALLKEAL
                     RQNKPIMAICRGVQLVNVAFGGTLNQEIEGHWQGLPFGTSHSIETVEGSVVAKLFGKE
                     SQVNSVHRQSIKDLAPNFRVTAIDSRDQTIEAIESIDEHRIIGLQWHPEFLVNEEDGN
                     LELFEYLLNEL"
     gene            10586..10765
                     /locus_tag="VQ862_001648"
     CDS             10586..10765
                     /locus_tag="VQ862_001648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3115961.1"
                     /translation="MEHLVVLSFIFSKFLECGILRKRLNSDKNWRNSTKKLEKNEGKR
                     YDRKEEILEEEHVTY"
     gene            10752..12101
                     /locus_tag="VQ862_001649"
     CDS             10752..12101
                     /locus_tag="VQ862_001649"
                     /EC_number="5.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate isomerase"
                     /protein_id="HET3115962.1"
                     /translation="MSHIKFDYSKVLDKFVAPHEVEYMQSQVTAADELIRKGTGAGSD
                     FLGWLDLPEKYDREEFDRILKAAEQIKSDSDVLVVIGIGGSYLGAKAAIDFLNHHFAN
                     LQTKEERKAPQILYAGNSISSTYLADLVEYVADKDFSVNVISKSGTTTEPAIAFRVFK
                     ELLVKKYGQEEANKRIYATTDRQKGAVKVEADANGWETFVVPDDIGGRFSVLTAVGLL
                     PIAASGADIKALMEGANAARKDYTSDKISENEAYQYAAVRNILYRKGYATEILVNYEP
                     SLQYFSEWWKQLAGESEGKDQKGIYPTSANFSTDLHSLGQFIQEGTRIMFETVVRVDK
                     PRKNVLIPTLEEDLDGLGYLQGKDVDFVNKKATDGVLLAHTDGDVPNMYVTLPEQDAF
                     TLGYTIYFFELAIALSGYLNAINPFDQPGVEAYKRNMFALLGKPGFEELSKELNARL"
     gene            12225..13685
                     /locus_tag="VQ862_001650"
     CDS             12225..13685
                     /locus_tag="VQ862_001650"
                     /EC_number="6.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--tRNA ligase"
                     /protein_id="HET3115963.1"
                     /translation="MSKDIRVRYAPSPTGLLHIGNARTALFNYLYARHHGGTFLIRIE
                     DTDRKRHVEDGERSQLENLRWLGMDWDESPESHENYRQSERLDLYQKYIDQLLAEGKA
                     YKSYVTEEELAAERERQEVAGETPRYINEYLGMSEEEKAAYIAEREAAGIIPTVRLAV
                     NESGIYKWHDMVKGDIEFEGGNIGGDWVIQKKDGYPTYNFAVAIDDHDMQISHVIRGD
                     DHIANTPKQLMVYESLGWEAPEFGHMTLIINSETGKKLSKRDTNTLQFIEDYRKKGYL
                     PEAVFNFIALLGWNPGGEDEIFSREELIKLFDENRLSKSPAAFDQKKLDWMSNDYIKN
                     ADLETIFEMAKPFLEEAGRLTDKAEKLVELYKPQMKSVDEIIPLTDLFFSDFPELTEA
                     EREVMTGETVPTVLEAFKAKLEAMTDDKFVTENIFPQIKAVQKETGIKGKNLFMPIRI
                     AVSGEMHGPELPDTIFLLGREKSIQHIENMLKEISK"
     gene            13699..14133
                     /locus_tag="VQ862_001651"
     CDS             13699..14133
                     /locus_tag="VQ862_001651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HET3115964.1"
                     /translation="MDIWEKMYEEAQKLYNPHEVSDFVYANHVVAAVEAEDGQIFTGF
                     CMEGTCGVFHLCAERAALFNMYQFSGQTKVKKVLAFRDKPPYGGSSAMPCGACREFLL
                     ELNAENKDAEFMMDYNIRKTVKVAELIPYWWGEERASKFNER"
BASE COUNT         4150 a         2739 c         3191 g         4100 t
ORIGIN      
        1 ctaacagttg aagatcaagc ctataaccat gcgctatcca aggagagaag caaggtcgag
       61 aacatctttg ccaaagtaaa aacgtttaaa atgttttcaa caacctatcg aaatcatcgt
      121 aaacgcttcg gattacgaat gaatttgatt gctggtatta tcaatcatga actaggattc
      181 tagttttgca ggaagtctat tatttggtta ggtgaattag tgaagcgttt aggcaagtgt
      241 ctctggttac gacgtcatgg cctctaaatc gattatattt aggggtcatg actagtgaag
      301 cagttagcta gttcgcatat aagcggctag cgtctaacaa ttaggaactt tagttccaat
      361 aactttaaga ttacgacgtt ttaggacata aatcgatcat atttatgtcc taaaactagt
      421 gaagcgccta gccaaagtcc gaataggatt tggcgttagt tacttagatt gctttgcaat
      481 caagtaactt tggcgattta catcttctct ggcgcttcta ctccaagcaa gcgaagggct
      541 tcttttagaa cgactgcggt tgcgtagctg agggctagac ggctgtcgcg ttctgggctt
      601 tcatccaaga tacgtgtatg tgcatagtat ttgttaaagg attgagctag gctaattgca
      661 aatttagcaa tgatagaagg ttcaaagtta tctgccgcac ggttgataat acgtgggaag
      721 tcttgaatga gtttaatgat ttcccagctt tcagtatcat tcaagctata gttgccagct
      781 gtttctggtt tgaaatcggc tttgcgtaag atagattgga tacgagcgta ggcatattga
      841 acgtaaggtc cagtttcacc ctcgaaggat accatagctt ctaggtcgaa gtcgtatcca
      901 tttgtacggt cggttttgag gtcatagaat ttaatggctc caaccccaac agcatgtgct
      961 acttggtctt tgttttctag ttcaggattt ttagcctcga tttggacctt ggcacggcta
     1021 acagcctctg caacagtagg ctctagcaag atgacattcc ctttacgagt agagagcttc
     1081 ttcccttcct ttgtaaccaa accaaaagga acgtgagtaa tgtcgtcact ccagtcgtag
     1141 cccatctctt gcaagacagc tttgagctgt ttaaagtggg cagattgttc ttgaccaacg
     1201 acatagatag atttagcaaa ttggtattcg tttttacggt aaagggctgc agccaagtca
     1261 cgtgtgatat agagagttgc accatcagac ttcttgatga gggctggatg ttcaattcca
     1321 tatttctcaa gattcacaac ttgggcacct tctgattcaa gaagtagtcc tttttcagaa
     1381 agaatgtcta caactgcatc catcttatca ttgtagaagg cttctccgtt atagctgtca
     1441 aattcaacct tcaattcatt gtaaaggcgg ttaaattcca ctaaactttc atcgcggaac
     1501 cattgccaaa gagcgagagc ttcctcatct ccattttcaa gtttacggaa ccattcgcgc
     1561 gcttcttcat ccaagctagg gtcattttca gcttcagcgt tgatgcggac atagagttta
     1621 aggagttcat cgattggatg agcttttaca gcttcttcgt cgccccattt tttgtaggca
     1681 acaatcaaca tcccaaattg tttaccccag tctcccaaat ggttgacctt gaccgtttga
     1741 taaccgattt tttggaaaat atgtgacaag ctatctccga taacagttga acgcaggtgg
     1801 ccaatagaaa atggtttagc gatattcgga ctagacatgt cgataacaac attttcttgt
     1861 ttgccaatat tttggtcagc atagtgttct ttttcagttg taacagcttg caatacttga
     1921 gcagaaatgg cagatttatc aaggaaaaag ttaacgtaag gtcctgttgc gacaactttt
     1981 tcaaaggctt ggctgttcat tttttcagcc agttcagccg caatcatttg tggtgcttta
     2041 cgttcgactt tggcaagaga aaaagcaggg aaagcgatgt cacccatttc tgagttttta
     2101 ggggtttcca gtaactttaa aatagcctct tggtccaggc tatcaatgat gctagccaat
     2161 tcgctagcaa tcaattcttt tgtattcatt aagagctcct ttttggactt ttctactatt
     2221 ttaacacaat tttaaagaaa gaagaaaaaa tttttgaaat ctcttgtttt tttggtataa
     2281 tatggttata aatatagtta taaatatgca cgcaagagga ttttatgaga aaaagagatc
     2341 gtcatcagtt aataaaaaaa atgattactg aggagaaatt aagtacacaa aaagaaattc
     2401 aagatcggtt ggaggcgcac aatgtttgtg tgacgcagac aaccttgtct cgtgatttgc
     2461 gcgaaatcgg cttgaccaag gtcaagaaaa atgatatggt gtattatgta ctagtaaatg
     2521 agacagaaaa gattgatttg gtggaatttt tgtctcatca tttagaaggt gttgcaagag
     2581 cagagtttac cttggtgctt cataccaaat tgggagaagc ctctgttttg gcaaatattg
     2641 tagatgtaaa caaggataaa tggattttag gaacagttgc tggtgccaat accttattgg
     2701 ttatttgtcg agatcagcac gttgccaaac tcatggaaga tcgtttgcta gatttgatga
     2761 aagataagta aggtcttggg agttgctctc aagacttatt tttgaaaagg agagacagaa
     2821 aatggcgata gaaaagctat cacccggcat gcaacagtat gtggatatta aaaagcaata
     2881 tccagatgct tttttgctct ttcggatggg tgatttttat gaattatttt atgaggatgc
     2941 ggtcaatgct gcgcagattc tggaaatttc cttaacgagt cgcaacaaga atgccgacaa
     3001 tccgatccct atggcgggtg ttccctatca ttctgcccaa cagtatatcg atgtcttgat
     3061 tgagcagggt tataaggtgg ctatcgcaga gcagatggaa gatcctaaac aagcagttgg
     3121 ggttgttaaa cgagaggttg ttcaggtcat tacgccaggg acagtggtcg atagcagtaa
     3181 gccggacagt cagaataatt ttttggtttc catagaccgc gaaggcaatc aatttggcct
     3241 agcttatatg gatttggtga cgggtgactt ttatgtgaca ggtcttttgg atttcacgct
     3301 ggtttgtggg gaaatccgta acctcaaggc tcgagaagtg gtgttgggtt atgacttgtc
     3361 tgaggaagaa gaacaaatcc tcagccgcca gatgaatctg gtactctctt atgaaaaaga
     3421 aagctttgaa gaccttcatt tattggattt gcgattggca acggtggagc aaacggcatc
     3481 tagtaagctg ctccagtatg ttcatcggac tcagatgagg gaattgaacc acctcaaacc
     3541 tgttatccgc tacgaaatta aggatttctt gcagatggat tatgcgacca aggctagtct
     3601 ggatttggtt gagaatgctc gctcaggtaa gaaacaaggc agtcttttct ggcttttgga
     3661 tgaaaccaaa acggctatgg ggatgcgtct cttgcgttct tggattcatc gccccttgat
     3721 tgataaggaa cgaatcgtcc aacgtcaaga agtagtgcag gtctttctcg accatttctt
     3781 tgagcgtagt gacttgacag acagtctcaa gggtgtttat gacattgagc gcttggctag
     3841 tcgtgtttct tttggcaaaa ccaatccaaa ggatctcttg cagttggcga ctaccttgtc
     3901 tagtgtgcca cggattcgtg cgattttaga agggatggag caacctactc tagcctatct
     3961 catcgcacaa ctggatgcaa tccctgagtt ggagagtttg attagcgcag cgattgctcc
     4021 tgaagctcct catgtgatta cagatggggg aattatccgg actggatttg atgagacttt
     4081 agacaagtat cgttgcgttc tcagagaagg gactagctgg attgctgaga ttgaggctaa
     4141 ggagcgagaa aactctggta tcagcacgct caagattgac tacaataaaa aggatggcta
     4201 ctattttcat gtgaccaatt cgcaactggg aaatgtgcca gcccactttt tccgcaaggc
     4261 gacgctgaaa aactcagaac gctttggaac cgaagaatta gcccgtatcg agggagatat
     4321 gcttgaggcg cgtgagaagt cagccaacct cgaatacgaa atatttatgc gcattcgtga
     4381 agaggtcggc aagtacatcc agcgtttaca agctctagcc caaggaattg cgacggttga
     4441 tgtcttacag agtctggcgg ttgtggctga aacccagcat ttgattcgac ctgagtttgg
     4501 tgacgattca caaattgata tccggaaagg gcgccatgct gtcgttgaaa aggttatggg
     4561 ggctcagacc tatattccaa atacgattca gatggcagaa gataccagta ttcaactggt
     4621 tacagggcca aacatgagtg ggaagtctac ctatatgcgt cagttagcca tgacggcggt
     4681 tatggcccag ctgggttcct atgttcctgc tgaaagcgcc catttaccga tttttgatgc
     4741 gatttttacc cgtatcggag cagcagatga cttggtttcg ggtcagtcaa ccttcatggt
     4801 ggagatgatg gaggccaata atgccatttc gcatgcgacc aagaactctc tcattctctt
     4861 tgatgaattg gggcgtggaa ctgcaactta tgacgggatg gctcttgctc agtccatcat
     4921 cgaatatatc catgagcaca tcggagctaa gaccctcttt gcgacccact accatgagtt
     4981 gactagtctg gagtctagtt tacaacactt ggtcaatgtc cacgtggcaa ctttggagca
     5041 ggatgggcag gtcaccttcc ttcacaagat tgaaccggga ccagctgata aatcctacgg
     5101 tatccatgtt gccaagattg ctggcttgcc agcagacctt ttagcaaggg cggataagat
     5161 tttgactcag ctagagaatc aaggaacaga gagtcctcct cccatgagac aaactagtgc
     5221 tgtcactgaa cagatttcac tctttgatag ggcagaagag catcctatcc tagcagaatt
     5281 agctaaactg gatgtgtata atatgacacc tatgcaggtt atgaatgtct tagtagagtt
     5341 aaaacagaaa ctataaaacc aagactcact agttaatcta gctgtatcaa ggagacttct
     5401 ttgacaattc tccacttttt tgctagaata acatcacaca aacagaatga aaaggagctg
     5461 acgcattgtc gctccctttt gtctattttt taaggagaaa gtatgctgat tcagaaaata
     5521 aaaacctaca agtggcaggc cctggcttcg ctcctgatga caggtttgat ggttgctagt
     5581 tcacttctgc aaccgcgtta tctgcaggaa gtcttaggcg ccctccttac tgggaaatat
     5641 gaagctattt atagtatcgg ggcttggttg attggtgtgg ccgtagtcgg tctagttgct
     5701 ggtggactca atgttgtcct cgcagcctat attgcccaag gagtttcatc cgaccttcgg
     5761 gaggatgcct tccgtaaaat tcaaaccttt tcttatgctg atattgaaca atttaatgcg
     5821 ggaaatctag tcgttcgaat gacaaatgat atcaaccaga ttcagaacgt tgtcatgatg
     5881 accttccaga ttcttttcag acttcccctc ttgttcatcg gttcgtttat cctagcggtt
     5941 caaaccttac cttctctgtg gtgggtgatt gttctcatgg tagtcttgat ttttggtttg
     6001 actgctgtca tgatgggaat gatggggcct cgttttgcca agtttcaaac ccttcttgag
     6061 cgcatcaatg ccattgccaa ggaaaattta cgtggcgttc gtgtggtcaa gtcctttgtc
     6121 caagaaaaag agcaatttgc taagtttaca gaggtctcag acgagcttct tggtcaaaac
     6181 ctttacattg gttatgcctt ttcagtagtg gaacccttta tgatgttggt tggttacggg
     6241 gcggtcttcc tctctatttg gctggtcgcg ggaatggttc agtcggatcc gtctgttgtt
     6301 ggttccatcg cttcttttgt taattaccta agccagatta tctttaccat tgttatggtt
     6361 ggatttttgg gaaattctgt cagccgtgcc atgatttcca tgcgtcgtat tcgagaaatt
     6421 cttgacgcag agccagctat gaccttcaag gatatcccag atgaagagtt ggttggaagc
     6481 cttagctttg aaaatgtgac ctttacctat ccaatggaca atgaaccgat gctgaaagat
     6541 gtgagcttta ctattgaacc tggtcaaatg gttggtgtag ttggagcgac tggtgcagga
     6601 aagtcaacct tggctcaatt gattccacgt ctctttgatc cacagaacgg ggccattaaa
     6661 atcggtggca aggatattcg agaagtgagt gaaggaaccc tgcgtaaaac agtttccatc
     6721 gttctccaac gtgccattct ttttagtgga acgattgcag ataacttgag acaggggaag
     6781 ggaaatgcta ctctatttga aatggagcgc gcagccaata ttgcccaggc tagtgaattc
     6841 attcatcgta tggagaaaac ctttgaaagt ccagttgaag aacggggaac caatttctct
     6901 ggtggacaaa aacaaaggat gtcgattgcg cgtgggattg tcagcaatcc acgtattctg
     6961 atttttgacg attcgacctc agccttggat gccaaatcag agcgcttggt gcaagaagct
     7021 ttgaataagg acttgaaggg gacgacaacc attattattg ctcaaaaaat tagctcggtt
     7081 gtccatgcag acaagatctt ggttctaaat caaggacgat tgattggtca aggcacgcat
     7141 gcagacttgg ttgccaacaa tgccgtttac cgtgaaatct atgaaacaca gaaatgaaag
     7201 acaaactata agaaaagtca atagttttat ctaaattatt tcttatttca atttgatgat
     7261 ttggcgatga ttttagagca cggcaaaaag cccttgaaaa agtccatttt ttcaaaggta
     7321 atcctgtgtt gatttcagaa attacatcac tttttgttcg tcaaatggca gctctttttt
     7381 aggatataaa acagggttcg gataagtttt tttgtaaggt ggatgatggc tacattgtaa
     7441 tgttttcctt attctaactt agtcttaaga taggccttaa aagcaggtga aaagcgaggg
     7501 catgctttgg cagcttgtat gagtgcctac cgcagatgag gggaaccccg tttgatcatt
     7561 cttccagcta aatcaatctg atctgactga taaatagaag aatccagtcc agcgaaagct
     7621 tgtaattgag caggattatc aaaggcatga atattttgaa tctcggctaa aatgaccgcc
     7681 cctaaacgat tcccaatccc agtaaccgtc gtgatgatcg agttgaactc agccatcaag
     7741 tcattgacac atgtttccgc cttgtcaatg agcctcttgt aatgtttgat gttttcatta
     7801 cacgagataa aacgtttatg cgttatcaaa ctcatgacca attgaaacaa aaagctgtgg
     7861 ttagatcctt tcggaaattg tcaagcgatt ggaggaaatg aactaatcca cagcggctta
     7921 ttccaagtat accacttggg ctttggcagt agctaactgc gctaaatata atataaggag
     7981 gagtaaaatg aagacagttc aatttttttg gcattatttt aaggtttaca agttctcatt
     8041 tgtagttgtc atcctgatga ttgttctggc gacttttgcc caagccctct ttccagtctt
     8101 ttctggacaa gcggtgacgc agctagccaa tttagttcaa gcttatcaaa atggcaatcc
     8161 agaacttgta tggcaaagcc tatcaggaat catggtcaat cttggcctgc tggttttggt
     8221 tctatttatc tctagtgtaa tatacatgtg tctcatgacg cgcgtgattg cagaatcgac
     8281 caacgagatg cgcaaaggcc tctttggtaa gcttgctcag ttgacggttt ctttctttga
     8341 ccgtcgacaa gatggcgata tcctgtctca ttttaccagt gatttggata atatcctcca
     8401 agcctttaac gaaagcttga ttcaggtcat gagcaatatt gttttataca ttggtctgat
     8461 tcttgtcatg ttttcgagaa atgtgacgct ggctctcatc accattgcca gcaccccatt
     8521 ggctttcctt atgctgattt tcatcgtgaa aatggcacgc aaatacacca acctccagca
     8581 gaaagaggta gggaagctca acgcctatat ggatgagagc atctcaggcc aaaaagccgt
     8641 gattgtgcaa ggaattcaag aggatatgat ggcaggattt cttgaacaaa atgagcgcgt
     8701 gcgcaaggca acctttaaag gaagaatgtt ctcaggaatt cttttccctg tcatgaatgg
     8761 gatgagcctg attaatacag ccatcgtcat ctttgctggt tcggctgtac ttttgaatga
     8821 taagtctatt gaaacaagta cagccctagg tttgattgtt atgtttgcac aattttcaca
     8881 gcagtactac cagcctatta tccaagttgc agcgagttgg ggaagccttc agttggcctt
     8941 tactggagct gaacgaattc aggaaatgtt tgatgcagag gaggaaatcc gacctgaaaa
     9001 ggctccaacc ttcactaagt tgcaagaaag tgttgaaatc agtcatatcg atttttcata
     9061 cttgcctgat aaacctattt tgaaagatgt cagcatttct gcccctaaag gccagatgac
     9121 agcagttgtt gggccgacag gttcaggaaa aacgactatt atgaacctca tcaatcgctt
     9181 ttatgatgtt gatgctggtg gtatttattt tgatggtaaa gacattcgtg gctatgactt
     9241 agatagtctt agaagcaagg tgggaattgt attgcaagat tcggtcttgt ttagcggaac
     9301 gattcgagac aatatccgat ttggtgtgcc agatgctagt caggaaatgg ttgaggtagc
     9361 agcaaaagca acccacattc acgactatat cgaaagtttg cctgataagt acgatactct
     9421 tattgatgat gaccagagca tcttttcaac agggcagaag caattgattt caatcgctcg
     9481 aaccctgatg acagatccag aagttctcat tctcgatgaa gcaacttcaa acgtagatac
     9541 ggtgacagaa agcaagattc agcatgccat ggaggtggtt gtagcaggta gaactagttt
     9601 cgtcattgcc caccgcttga aaaccattct caatgcagat cagattattg tccttaaaga
     9661 tggagaagtc attgaacgtg gtaaccacca tgaacttttg aagctaggtg gcttttattc
     9721 agaactctat cacaatcaat ttgttttcga atgagaaaga agttgtccta tgtgggcagc
     9781 tttttcttgt ccataaaaaa tgtttatcac agccttaaaa aaaacatatt agacgaaagt
     9841 cattttgagt gatatgatag gactatcgtt agcattcgaa aggagaggca tcatggctag
     9901 aacggttgta ggagttgctg caaatctatg tcccgtagac gcagaaggca aaatcattca
     9961 ttcatctgta tcttgtagat tcgcagagat cattcgtcaa gtcggtggtc tccctttagt
    10021 cattcctgtt ggtgatgagt cagttgtacg tgattatgtg gaaatgattg acaaactcat
    10081 tttgacagga ggccaaaatg ttcatcctca gttttatgga gagaaaaaga ccgtcgagag
    10141 cgatgattac aatctggtcc gtgacgaatt tgaattggca ctcttgaagg aagcgcttcg
    10201 tcagaataaa ccaattatgg caatctgtcg cggtgtccaa cttgtcaatg ttgcctttgg
    10261 tggaaccctc aatcaagaaa tcgaaggtca ctggcaagga ctacctttcg ggacatctca
    10321 ctctattgag acagtagaag gaagcgtggt ggctaagcta tttgggaaag aaagtcaggt
    10381 caattcagtc catcgtcaaa gcattaaaga tttggcaccc aatttccgtg taactgctat
    10441 tgattcaaga gaccaaacta ttgaagcgat tgagtctatc gacgagcacc gcattatcgg
    10501 tttacagtgg catccagagt ttctggttaa tgaagaagat ggcaatttag aattatttga
    10561 gtatttattg aatgaactgt aacgattgga acatctggtc gttctttctt ttattttttc
    10621 aaaattttta gaatgtggta ttttacgcaa acgtttgaat tctgataaaa attggagaaa
    10681 ttcgacaaaa aaacttgaaa aaaacgaagg taagcgttat gatagaaaag aagaaatatt
    10741 ggaggaagaa catgtcacat attaaatttg attattcaaa agttttagac aaatttgttg
    10801 caccacatga agtggaatac atgcaatcac aagtaacagc agcagatgaa ttgatccgta
    10861 aaggaactgg tgctggtagc gacttcttgg gatggttgga ccttcctgaa aaatacgacc
    10921 gcgaagaatt tgaccgcatc ttgaaagctg ctgagcaaat caagtcagac agcgatgttt
    10981 tggttgtgat cggtattggt ggatcttacc ttggtgcaaa agcagcaatc gacttcttga
    11041 atcaccattt tgctaacttg caaacaaaag aagaacgcaa agctccacaa atcctttacg
    11101 caggaaactc aatctcatct acttaccttg ctgacttggt agagtatgtt gcagacaaag
    11161 acttctcagt aaacgtaatt tctaaatcag gtacaacaac tgaaccagcg attgctttcc
    11221 gtgtctttaa agaactcttg gttaagaaat acggtcaaga agaagctaac aaacgtatct
    11281 atgcaacaac tgaccgccaa aagggtgctg ttaaggttga agcagacgct aacggttggg
    11341 aaacatttgt tgttccagat gatatcggtg gacgcttctc agtattgaca gccgttggtt
    11401 tgcttccaat cgcagcatca ggagctgaca tcaaagctct tatggaaggt gcgaatgcag
    11461 ctcgcaaaga ctacacttca gacaaaatct ctgaaaacga agcttaccaa tacgcagctg
    11521 ttcgtaacat cctttatcgt aaaggctatg caactgagat cttggtaaac tatgagccat
    11581 cacttcaata cttctcagaa tggtggaaac aattggctgg tgaatcagaa ggaaaagacc
    11641 aaaaaggtat ctacccaact tcagccaact tctcaactga cttgcactca cttggtcaat
    11701 ttatccaaga aggaactcgt atcatgtttg aaacagttgt ccgtgttgac aaacctcgta
    11761 aaaacgtgct tattcctact ttggaagaag accttgacgg acttggttac cttcaaggaa
    11821 aagacgttga ctttgtaaac aaaaaagcaa ctgacggtgt tcttcttgcc cacacagatg
    11881 gtgatgtacc aaacatgtat gtgactcttc cagagcaaga cgctttcact cttggttaca
    11941 ctatctactt cttcgaattg gcaattgccc tttcaggtta cttgaatgct atcaacccat
    12001 ttgaccaacc aggtgttgaa gcttataaac gtaacatgtt tgcccttctt ggaaaaccag
    12061 gatttgaaga attgagcaaa gaacttaacg cacgtctata atagaagaaa agagtggttt
    12121 acccactctt tttactctct ttatccatag aaattggact cagtcaagac ttgtgatata
    12181 atatagaaag caaaaaggca gatgcctaga taataggaga aactatgtca aaagatatcc
    12241 gcgtacgtta cgcaccaagt ccaacaggac tactacacat cggaaatgct cgtacagcat
    12301 tgtttaatta cttgtatgcg cgccatcatg gtggaacatt tctcatccgt atcgaagata
    12361 ctgaccgtaa acgccatgtc gaggatggtg aacgttcaca acttgaaaac cttcgctggt
    12421 taggcatgga ttgggatgaa agtccagaat cacatgagaa ttatcgccag tctgagcgtt
    12481 tagacttgta tcaaaaatac attgaccaac tattagctga aggaaaagcc tataaatctt
    12541 acgttacaga agaagagttg gcagctgaac gcgaacgcca agaagtagct ggcgaaacac
    12601 cacgctacat caatgaatac cttggtatga gtgaagaaga aaaagcagct tacatcgcag
    12661 aacgtgaagc agcagggatc atcccaactg ttcgtttggc tgtcaatgag tcaggtatct
    12721 acaagtggca tgatatggtc aaaggcgata tcgaatttga aggtggcaat atcggtggtg
    12781 actgggttat ccaaaagaaa gacggttacc caacttacaa ctttgccgtt gccatcgatg
    12841 accacgatat gcaaatctct catgttatcc gtggagatga ccatattgct aatacaccaa
    12901 aacagcttat ggtctatgaa tctcttggtt gggaagctcc agagttcggt cacatgacct
    12961 tgattatcaa ctctgagact ggtaagaagt tatctaaacg tgatactaat acacttcaat
    13021 ttatcgaaga ttaccgaaag aaaggttacc ttccagaagc agtctttaac tttattgctc
    13081 ttcttggttg gaacccaggt ggtgaagatg agattttctc tcgtgaagaa ctcattaaac
    13141 tttttgatga aaaccgcctc agcaagtcac cagcagcctt tgatcagaaa aaactagact
    13201 ggatgagcaa tgattatatc aagaatgcag accttgaaac catctttgaa atggcaaaac
    13261 cattcttaga ggaagcaggc cgtttgactg acaaggctga aaaattagtt gagctctata
    13321 aaccacaaat gaaatcagta gatgagatta tcccattgac agatcttttc ttctcagatt
    13381 tcccagaatt gacagaagca gagcgcgaag tcatgacggg tgaaacagtt ccaacagttc
    13441 ttgaagcatt caaagcaaaa cttgaagcga tgacagatga taaatttgtg acagaaaata
    13501 tcttcccaca aattaaagca gttcaaaaag aaacaggtat taaagggaaa aatcttttca
    13561 tgcctattcg tatcgcagtt tcaggcgaaa tgcatgggcc agaattacca gatacaattt
    13621 tcttgcttgg acgtgaaaaa tcaattcagc atatcgaaaa catgctaaaa gaaatctcta
    13681 aataaagagg atacaataat ggacatctgg gaaaagatgt acgaagaagc acagaaacta
    13741 tacaatccac atgaagtatc agactttgtt tatgccaatc atgttgtagc tgcagtagaa
    13801 gcagaagatg gacaaatatt tacaggattc tgtatggagg gaacctgtgg tgttttccat
    13861 ctctgcgcag aacgggcggc cctcttcaat atgtaccaat tttcaggaca aactaaggtt
    13921 aagaaagtat tagcctttcg agacaaacca ccttatggtg gaagttcagc catgccttgc
    13981 ggtgcttgta gagaattcct tttagagctt aatgctgaaa ataaagatgc agaattcatg
    14041 atggactata atataagaaa aacagttaaa gtcgcagaac taatccctta ttggtgggga
    14101 gaagaacgtg cttctaagtt taatgagcga tagaagagtc agtataattt tggctctttt
    14161 tactataagt tgaaaaaata
//
LOCUS       DAVBOD010000050        13702 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 640-05
            SAMEA1012484-rid20186543.denovo.050, whole genome shotgun sequence.
ACCESSION   DAVBOD010000050 DAVBOD010000000
VERSION     DAVBOD010000050.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012484
            Sequence Read Archive: ERR059358
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 13702)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13702)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979948.1
            Genome Coverage       :: 595x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:03:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,266
            CDSs (total)                      :: 2,219
            Genes (coding)                    :: 2,091
            CDSs (with protein)               :: 2,091
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 71 of 128
            Pseudo Genes (incomplete)         :: 50 of 128
            Pseudo Genes (internal stop)      :: 33 of 128
            Pseudo Genes (multiple problems)  :: 22 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13702
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012484-rid20186543.denovo.050"
                     /strain="NIG 640-05"
                     /db_xref="taxon:1313"
     gene            complement(482..707)
                     /locus_tag="VQ862_001652"
                     /pseudo
     CDS             complement(482..707)
                     /locus_tag="VQ862_001652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001824185.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
     gene            1555..2427
                     /locus_tag="VQ862_001653"
     CDS             1555..2427
                     /locus_tag="VQ862_001653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000749590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4300 family protein"
                     /protein_id="HET3115965.1"
                     /translation="MKKSRKLATLGICSALFLGLAACQQQHATSEGTNQRQSSSAKVP
                     WKASYTNLNNQVSTEEVKSLLSAHLDPNSVDAFFNLVNDYNTIVGSTGLSGDFTSFTH
                     TEYDVEKISHLWNQKKGDFVGTNCRINSYCLLKNSVTIPKLEKNDQLLFLDNDAIDKG
                     KVFDSQDKEEFDILFSRVPTEATTDVKVHAEKMETFFSQFQFNEKARMLSVVLHDNLD
                     GEYLFVGHVGVLVPADDGFLFVEKLTFEEPYQAIKFASKEDCYKYLGTKYADYTGEGL
                     AKPFIMDNDKWVKL"
     gene            complement(2573..2917)
                     /locus_tag="VQ862_001654"
                     /pseudo
     CDS             complement(2573..2917)
                     /locus_tag="VQ862_001654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
     gene            3060..3372
                     /locus_tag="VQ862_001655"
                     /pseudo
     CDS             3060..3372
                     /locus_tag="VQ862_001655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521917.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            3376..4092
                     /locus_tag="VQ862_001656"
     CDS             3376..4092
                     /locus_tag="VQ862_001656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HET3115966.1"
                     /translation="MKKYFIGGLGSNAYHSKDFLQELDSQVYFLNPYEKHLRDETELK
                     SWFKNEIVEEESICLIGHSIGGDLARYFASEFEEVKKLILLDGGYLDLDKILPLDTEL
                     EETKNYIKSQIISDLDVLTSKEKSEAKHWSENMEKAVRQSYHWNVEYNRYELAINYEN
                     IEAILRLRRKIQAFKREVGDTLFISPRYPNEATWREEALKELPDYFDTIFLENFGHEL
                     YTQAPKEIASLMNEWLAYFL"
     gene            complement(4222..5037)
                     /locus_tag="VQ862_001657"
     CDS             complement(4222..5037)
                     /locus_tag="VQ862_001657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000617844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03943 family protein"
                     /protein_id="HET3115967.1"
                     /translation="MIRFLVLAGYFELTIYLHLSGKLNQYINMHYSYLAYISMVLSFI
                     LAIVQLYIWMKQVKTHSHLNSRLAKMTSISLLAIPLVIGLTFPTVSLDSQTVSAKGYH
                     FPLSEGTDLAIQTSEGTTSQYLKPDTSSYFSKSAYEKEMRTAADKYLSQDSIQITNEN
                     YMEVMEAIYDYPDEFEGKTIQFTGFVYNDPSHANSQFLFRFGIIHCIADSGVYGLLTK
                     GNTRQYENNTWISAKGKLVNHYHKELKQNLPTLEIDSFTKVDKPENPYVYRAF"
     gene            complement(5034..5939)
                     /locus_tag="VQ862_001658"
     CDS             complement(5034..5939)
                     /locus_tag="VQ862_001658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HET3115968.1"
                     /translation="MTAFQQLPSSVLQTGAIFLSIIIEALPFVLIGSIVSGLIEVYIT
                     PDKVYHFLPRNRWGRIFFGTFVGMFFPSCECGIVPIINRFLEKKVPSYTAVPFLVTAP
                     VINPIVLFATYSAFGNSFHVALLRALGSILVAVILGIFLGFFWQEPIQKENRLACHEH
                     DFSYLSSAKKVFQVFVQAIDEFFDTGRYLVFGCLFASIIQVYVPTRILTSISATPLFA
                     ILLLMILAFLLSLCSEADAFIGASLLSSFGLAPVLAFLVIGPMLDIKNILMMKNYLKA
                     RFISHFITIVTLVVLVYSLLIGVIL"
     gene            6351..8480
                     /locus_tag="VQ862_001659"
     CDS             6351..8480
                     /locus_tag="VQ862_001659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000359105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding transcriptional accessory protein"
                     /protein_id="HET3115969.1"
                     /translation="MDKKYEKISQDLGVTLKQIDTVLSLTAEGATIPFIARYRKDMTG
                     SLDEVAIKAIIDLDKSLTNLNDRKEAVLAKIQEQGKLTKELEEAILVAEKLADVEELY
                     LPYKEKRRTKATIAREAGLFPLARLILQNIVDLEKEAEKFVCEGFATGKEALTGAVDI
                     LVEALSEDVTLRSMTYQEVLRHSKLTSQAKDESLDEKQVFQIYYDFSETVGTMQGYRT
                     LALNRGEKLGVLKIGFEHATDRILAFFATRFKVKNAYIDEVVQQSVKKKVLPAIERRI
                     RTELTEKAEEGAIQLFSDNLRNLLLVAPLKGRVVLGFDPAFRTGAKLAVVDATGKMLT
                     TQVIYPVKPASARQIEEAKKDLADLIGQYGVEIIAIGNGTASRESEAFVAEVLKDFPE
                     VSYVIVNESGASVYSASELARQEFPDLTVEKRSAISIARRLQDPLAELVKIDPKSIGV
                     GQYQHDVSQKKLSESLDFVVDTVVNQVGVNVNTASPALLSHVAGLNKTISENIVKYRE
                     EEGKITSRAQIKKVPRLGAKAFEQAAGFLRIPESSNILDNTGVHPENYTAVKELFKRL
                     DIKDLNEEAQSKLKSLSVKEMAQELDLGPETLKDIIADLLKPGRDFRDSFDAPVLRQD
                     VLDIKDLVVGQKLEGVVRNVVDFGAFVDIGIHEDGLIHISHMSRKFIKHPSQVVSVGD
                     LVTVWVKKIDTEREKVNLSLLAPNETD"
     gene            8467..8916
                     /locus_tag="VQ862_001660"
     CDS             8467..8916
                     /locus_tag="VQ862_001660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000778579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SprT family protein"
                     /protein_id="HET3115970.1"
                     /translation="MKLTDYVKQVSLEDFGRAFIHHVQWNRRLRSTGGRFFPKDGHLD
                     FNPKVYQKLGMEVFRKIVRHELCHYHLYFQGKGYQHKDRDFKELLKAVDGLRFVPSLP
                     NSNSKPLKLYRCQSCQQRYQRKRRIDTQRYRCGLCRGKLLLINQPED"
     gene            8975..9247
                     /locus_tag="VQ862_001661"
     CDS             8975..9247
                     /locus_tag="VQ862_001661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HET3115971.1"
                     /translation="MNSKFYKMRRNRMISGVLAGLSDKWNFDVTLVRFLFAIFTVANF
                     GLGVIIYIILASIMPTKEEIEAEMYGTGPRKRKEAQAIDDNEGWFW"
     gene            complement(9295..9459)
                     /locus_tag="VQ862_001662"
     CDS             complement(9295..9459)
                     /locus_tag="VQ862_001662"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3115972.1"
                     /translation="MDEAGEILLILFKNQSANYVNFTLPTKLQPVAGFLVCTLIFIEY
                     KSKKALNQAV"
     gene            complement(9601..9792)
                     /locus_tag="VQ862_001663"
     CDS             complement(9601..9792)
                     /locus_tag="VQ862_001663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000680763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3115973.1"
                     /translation="MKHKEHILIGLLYLLSPFIGQLLVEHTHFIGTEFTGTAYVICWL
                     SVVISIHHFSKNVLSQQQK"
     gene            10220..10978
                     /locus_tag="VQ862_001664"
     CDS             10220..10978
                     /locus_tag="VQ862_001664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000173375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3115974.1"
                     /translation="MTLLDVKHVQKIYKTRFQGNQVEALKDIHFTVEKGDYVAIMGES
                     GSGKSTLLNILAMLDKPSRGQVYLNGTDTATIKNSQASSFRREKLGFVFQDFNLLDTL
                     SVKDNILLPLVLSRRPITEMMKKLVMTAENLGINQLQEKYPYEISGGQKQRVAVARAI
                     ITEPEILLADEPTGALDSKSSAALLDVFNEINERGQTILMVTHSTAAASRAKRVLFIK
                     DGILYNQIYRGEKTERQMFQEISDTLTVMASEVN"
     gene            10980..12968
                     /locus_tag="VQ862_001665"
     CDS             10980..12968
                     /locus_tag="VQ862_001665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000489335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET3115975.1"
                     /translation="MFRLTNKLAVSNLIKNRKLYYPFALAVLLAVTITYLFYSLTFNP
                     KIAEIRGGTTIQATLGFGMFVVTLASAIIVLYANSFVMKNRSKELGIYGMLGLEKRHL
                     ISMTFKELVLFGILTVGAGIGIGALFDKLIFAFLLKLMKLKVELVATFQMKVVITVLL
                     VFGLIFLGLMFLNALRIARMNALQLSREKASGEKKGRFLPLQTILGSISLGIGYYLAL
                     TVKDPLTALTTFFIAVLLVIFGTYLLFNAGITVFLQILKKNKKYYYQPNNLISVSNLI
                     FRMKKNAVGLATIAILSTMVLVTMSAATSIFNSAESFKKVLNPHDFGVSGQNVEKEDL
                     DKLLSQFASDKGYKIKEKEVLRYTYFAVANQEGTKLTIFEKGQNRVQPKTVFMVFDQK
                     DYENMTGQKLSLSGNEVGLFAKNDGLKGQKALTLNDHQFSVKEEFNKDFIVNHVPNKF
                     NILTTDYNYLVVPDLQAFLDQFPDSAIYNQFYGGMNVDASEEEQLKVAEEYENYLNQF
                     NAQLDTEGSYVYGSNLADASSQMSALFGGVFFIGIFLSIIFMVGTVLVIYYKQISEGY
                     EDRERFIILQKVGLDQKQIKQTINKQVLTVFFLPLLFAFIHLAFAYHMLSLILKVIGV
                     LDTTMMLIVTLSICAIFLIAYVLIFMITSRSYRKIVQM"
     gene            complement(13010..13651)
                     /locus_tag="VQ862_001666"
     CDS             complement(13010..13651)
                     /locus_tag="VQ862_001666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000234620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VIT family protein"
                     /protein_id="HET3115976.1"
                     /translation="MRAGVLGANDGIISIAGVVIGVASATTNIWIIFLSGFAAILAGA
                     FSMAGGEYVSVSTPKDTEEAAVSREKLLLDQDRELAKKSLDAAYIQNGECKTSAQLLT
                     NKIFLKNPLKALVEEKYGIEYEEFTNPWHAAISSFVAFFLRSLPPMLSVTIFPSDYRI
                     PATVLIVGVALLLTGYTSARLGKDPTRTAMIRNLAIGLLTMGVTFLLEQLFSI"
BASE COUNT         4194 a         2551 c         2816 g         4141 t
ORIGIN      
        1 aaataagata tgtacaaatt gattagaaag tcaaatgaat ttctacaaat gttttagtaa
       61 tcgcaatcta cttgtctaga ttcgatctga tatattttcg atttaatgat atggtattta
      121 aaacctccaa agtagcttgc tccattcttt tacttacgtg agtgtagatg ttatttactg
      181 ttttagcgtt tttgtgttcc actctaacca ttatagcatt cttctcagct agtgtactaa
      241 ggagtgtgtg cctgaaaata tgggaactaa ggggctggtt tatcggtttc tctagtttag
      301 tatttgcctt ttgcaaagtg atgttaaatg cctttctcta aattcacata tcactattgt
      361 ttaacaaaat ctaatctact ttaggtcact tattcttttt ttgaaatgta gaatgaactt
      421 tttcaaagtt tttcgaatct tttaaaatct gtttgtttta tatcgccatt ctcccccttt
      481 tttaattctc cctatatagc ctgatagctt tcccgatggt acgaatatgg ttgctttcgt
      541 ctaggtggat gtcggggtat tcgggattga gtttttttga ggcagccttg gcggagtttc
      601 ttgacatagt tagtgccgtc tacttggaag atgccgatgg tattatagtc aatctgtggg
      661 gtattcttga taaataggta gtcgctgttt cttatctttg gctccatgga cttgctgacg
      721 acataagcga ttgggtcgta gtcgtctggg ataatggaaa ctccataact aaatcgtcgt
      781 cctgcatcga gcggctacct gcagagataa actacctaac acgagagtaa gtagtctgtc
      841 tgtagtcgtc cagtctgatg atttttacga tacttcgttt ttctgatcat acagttgcct
      901 ctcggcatag gtcagaactt taccttgtct gggtggtgcc cgttggtcgt agatagattg
      961 gatatcgcta ggagaatcct tttgaactgg aggaaagagg gcatcaatca agctactgaa
     1021 tactttaact aagtcaaata tagtattttt cttagtagac ctaacccttt tttcataatt
     1081 tctaatggtg tttttactta tacctatctt agtacccaat tcttattgag tccaaccatt
     1141 actagtctat attgttttat agttgattga gtttggaata gtacgctgta gctgctaaaa
     1201 catttctagg aattaatttg cctttcctaa tagagttgtt catatcttat ttcaatctat
     1261 tatatttttc gcctctaaca atcgcaatct cttctttatc tacgaacgaa atcgctttct
     1321 atttttgtaa gtaaagcatc acacgaaatc cacgaaaatg aaaacctttg ttgtgttttc
     1381 gtaaaaaatt tgttgacaga gcacgaaacg cctactataa ttaaatcaag tttaaggaaa
     1441 taacaaaaaa acaaatcgga gggaaagacg atgaacacat taaatgagaa agtaatcaat
     1501 atctgtaaag cagtagttaa agaaacttta atccaagaca tttaggagaa agaaatgaag
     1561 aaatcaagaa aattagccac attaggaatc tgttcagcct tgtttttagg cttggctgct
     1621 tgtcaacaac aacatgctac ttctgagggt acgaatcaaa ggcaaagcag ttcagcgaaa
     1681 gttccatgga aagcttcata caccaaccta aacaaccagg taagtacaga agaggtcaaa
     1741 tctctcttat cagctcactt ggatccaaat agtgttgatg cattttttaa tctcgttaat
     1801 gactataata ccattgtcgg ctcaactggc ttatcaggag atttcacttc ctttactcac
     1861 accgaatacg atgttgagaa aatcagtcat ctctggaatc aaaagaaggg cgatttcgtt
     1921 gggaccaact gccgtatcaa tagttattgt cttttgaaaa attcagtcac cattccaaag
     1981 cttgaaaaga atgaccagtt gcttttccta gataatgatg cgattgataa aggaaaggtc
     2041 tttgattcac aagataagga agagtttgat attctatttt cgagagttcc aactgaggca
     2101 actacagatg tcaaggttca cgctgaaaag atggaaacat tcttctcaca atttcaattc
     2161 aatgaaaaag ctcgaatgct gtctgtagtc ttgcacgaca atctggatgg cgagtatctg
     2221 tttgtaggcc acgttggggt cttagtacct gctgatgacg gtttcttatt tgtagagaaa
     2281 ttgactttcg aagagcccta ccaagcgatt aaatttgcta gtaaggaaga ttgctacaag
     2341 tatttgggca ccaagtatgc ggattataca ggcgagggac tggctaagcc ttttatcatg
     2401 gataatgata agtgggttaa actttaatag tgttatgata tgacagtaat cttaggattt
     2461 ttatttctat ttttgataag ttggtgggtt atttcaatcg ttaatagcca gaaaccacgc
     2521 aaaaatgaaa catttattgg ctatgtccaa agatacgata ttgatgggaa tggctatcaa
     2581 tcattaccgt gtcctcagaa ctgagaggag ttcttgaaat cgtaacacca ctttgaacaa
     2641 gagttacttc aacccattgg ctccgacgga gtaagttgct ttcgtggata ccaaaaacag
     2701 ccgcaatttg ttcataagtg cgatattctc gcacttattg aagagtggcc ataagaaggt
     2761 cttctaggct taatttaggt tttcgtccac cttttgcgtg tttaagttga taagctgttt
     2821 ttaatacagc taacatctct ttaaaagtcg tgcgttgaac accaacaaga cgcttaaatc
     2881 gtgcatcggt tagttgttta cttgcttcat aattcataga actattatac catattttgt
     2941 ttcgcaggaa gtctaatgct aaaatcttat cagtgagaag atttcttaaa gtttattctt
     3001 tgtagtttca tctgtattag tacataattt aacttagaga aaataggagg actaatcgaa
     3061 tggaattaaa agattttaca gaaaaagaac aggaaatgat taagaaaagg cttacaatgt
     3121 ctaatattag tgacaaagaa actactgaga agattctggc gctagtccca caagacttga
     3181 ttaagcgaat cccgtttttt gtcagaaaac atgctacaac acgtacgatt aaacgcattt
     3241 caattgaata ccctgaactc tacgctgtag ctcaaacaag tggtgagatt ccagaaaaaa
     3301 aaacgcgaag aattgcgtca gattatcaca actatctttg aacaaaagat gaataagcat
     3361 agtattaagt agagaatgaa aaaatatttt attggcggtt tgggaagcaa tgcctatcat
     3421 agcaaggatt ttcttcaaga actagattcg caggtctatt ttctaaatcc atatgaaaag
     3481 catcttcgag atgaaacaga attgaaatca tggtttaaaa atgagattgt agaggaagaa
     3541 tctatctgtc tgataggtca ttctattgga ggcgatttag ctcgttattt cgcatcggaa
     3601 tttgaagaag taaagaaact gattcttttg gatggtggct atctagattt agataagatt
     3661 ttacctttgg atacagagtt agaggaaact aaaaattata tcaaatctca aattatttcg
     3721 gacttagatg ttcttacttc taaagaaaaa tctgaagcaa agcattggtc agaaaatatg
     3781 gagaaagctg taagacagtc ctatcactgg aatgttgagt ataatagata tgagttggct
     3841 ataaattatg aaaatataga agcgatactc cgcctacgga gaaaaataca agcttttaag
     3901 agagaagtgg gagatacctt gtttattagt cctcgctatc ctaatgaagc tacatggaga
     3961 gaggaagccc taaaagaatt gccagactat tttgatacta tttttttaga aaactttggc
     4021 catgagcttt atactcaagc acctaaagaa atcgctagtc taatgaatga gtggctcgct
     4081 tattttctat gagctacttg tattgctgga aatggtataa gatgaaaatc tacaagtcac
     4141 taattttcat ataaccaaaa aacgaacagg ctctttttct gttattcaga agagaacttg
     4201 ttcgttttta tcttgatttt cttaaaaagc tctatataca tagggatttt ctggtttatc
     4261 gactttggta aagctgtcga tttccaaggt tggaaggttt tgtttgagtt ctttatggta
     4321 gtgattgacc agttttcctt tggctgaaat ccaagtgttg ttttcatact gccgggtatt
     4381 gcccttggtc agcaatccat agacaccaga atctgcgatg cagtgaataa tgccgaagcg
     4441 gaacagaaat tggctattgg catgactggg gtcattatag acaaagcctg tgaactggat
     4501 tgtcttaccc tcaaattcat ctggatagtc gtagatagcc tccatgacct ccatatagtt
     4561 ttcattagtg atctgaatac tatcttggga taagtattta tccgccgccg ttcgcatttc
     4621 cttttcatag gctgattttg aaaaataaga actggtatct ggtttcaaat attggcttgt
     4681 cgtcccttcg cttgtctgaa tggctagatc cgttccttcc gataggggga aatgataacc
     4741 tttagcagaa acggtctgag aatccaagct aacagttggg aaagttaagc cgatgacaag
     4801 tggaatagcc agaagagaaa tactcgtcat cttggctaat cggctgttca gatgactgtg
     4861 ggttttgact tgcttcatcc agatatacaa ttgaacgata gccaagataa aagaaagcac
     4921 catggagata taggccagat aggaatagtg catgttgatg tactggttta gtttgcccga
     4981 cagatggagg taaatagtca gttcaaaata gccagctaaa actaaaaatc gaatcatagg
     5041 atgactccaa tcaagagaga atagactaag acgacaagag ttacaattgt tatgaagtga
     5101 ctgataaatc gtgctttcaa gtaatttttc atcatgagaa tatttttgat atccagcatt
     5161 ggaccaatga cgagaaaggc cagaactggt gccaaaccga aactcgagag aagagaagca
     5221 cctataaagg catccgcctc actacagagc gaaagaagaa aggctaaaat catcaagagc
     5281 aggatggcaa aaagaggggt cgcactgata gaggtcagaa tccgagtcgg aacgtagacc
     5341 tgtattatag aagcaaagag gcagccaaat accaaataac gccccgtatc aaaaaattca
     5401 tcaatggcct gcacaaagac ttgaaaaact ttttttgcag aactcaagta agaaaaatca
     5461 tgctcatgac aagccagacg attttctttc tgaatcggtt cttgccagaa aaatcctaga
     5521 aaaattccta gtattacagc cacaagaatg gaacccagag ctcgtaatag ggcgacatgg
     5581 aaggagttgc caaaggcaga ataggtcgca aaaagaacaa tgggattgat aacaggtgct
     5641 gtcacaagaa aaggaacggc cgtgtaactt ggaacctttt tttccagaaa acgattgatg
     5701 atggggacga ttccacattc acaagaaggg aaaaacatac cgacgaaggt cccaaaaaag
     5761 attctccccc aacgatttcg agggagaaaa tgataaacct tgtcaggtgt gatataaact
     5821 tcaatcagcc ctgagacaat gcttcctatc agaacgaagg gaagggcttc aatgataatg
     5881 gagagaaaaa tggctccagt ttgaagtaca ctagatggga gttgttgaaa agcagtcatc
     5941 tagtttttct tttctgcttt ggcttttttc tctttgtcat cagggaaagt aacttgtttc
     6001 aaatcaggga gtttagcaaa ctcttcaaac atcttgtcca agtcgtctcg ttttgtaaat
     6061 tttacagcca taggtgtacc tcgattctaa attctacctc tattatacta ttattttgcg
     6121 gaaaagggag ttttttaatt tgttttcgat agttgatact cttcgaaaat ctcttcaaac
     6181 cacgtcagct tcgccttacc gtagtacggt tactgacttc gtcagttcta tccacaacct
     6241 caaaacagta ttttgagcag cctacggcta gcttcctagt ttgctttttg atttttattg
     6301 agtatgaaaa ggattggaga aagccttcca gcttgtggta taatagattt atggataaaa
     6361 aatatgaaaa aatctctcag gatttgggag tgacgttaaa gcaaattgat accgttctaa
     6421 gtttgacagc tgaaggggcg actattccct ttatcgcgcg ttatcgcaag gacatgactg
     6481 gtagtctgga tgaggtggcg attaaggcta ttattgattt ggataaaagt ctgacaaatc
     6541 tcaatgaccg taaggaagct gtcttagcta agattcaaga acaaggtaag ttgaccaagg
     6601 aattggaaga agctatctta gttgccgaaa aattagcaga cgttgaagaa ctctatcttc
     6661 cttataagga aaagcgtcgt accaaggcaa ccattgcccg tgaagctgga ctctttcctc
     6721 ttgctcgctt gattttgcag aatatagttg acttagagaa agaagctgaa aagttcgtct
     6781 gtgaaggatt tgcgactggc aaggaagcct tgaccggtgc agttgatatt ttggtcgaag
     6841 ccttatcgga agatgtgacc ttgcgttcta tgacttatca ggaagtgctg agacactcta
     6901 aactcacttc tcaagccaag gatgaaagtc ttgatgaaaa gcaggttttt cagatttatt
     6961 atgatttttc agagacagtt ggaactatgc aaggctatcg taccttggct ctcaatcgtg
     7021 gggagaaact tggtgtcttg aagatcggtt ttgaacatgc gacggaccgt attcttgcct
     7081 tctttgctac tcgtttcaag gtgaaaaatg cttatattga tgaagttgtt cagcaatccg
     7141 ttaagaaaaa ggtcttgcct gctatcgagc gtcgtattcg gacagaatta actgagaaag
     7201 ctgaagaagg agctatccaa cttttttctg acaatctgcg caatctcctc ttggttgctc
     7261 cactgaaagg gcgcgtggtt cttggatttg acccagcctt tcgtacaggt gccaagttag
     7321 ctgtcgtgga tgcaacagga aaaatgctga caactcaggt tatttatcct gttaaaccag
     7381 catcagctcg tcaaatcgaa gaagccaaga aagatttagc agatttaatt ggtcaatacg
     7441 gtgtagagat tattgccatt ggaaatggaa cggccagtcg tgaaagtgaa gcttttgtag
     7501 cggaagttct gaaagatttc cctgaagtca gctatgttat cgttaatgaa agtggtgctt
     7561 ctgtctattc tgccagcgaa cttgctcgtc aggagtttcc agacttgacc gttgaaaaac
     7621 gctctgccat ttctatcgcc cgtcgtttgc aagatcctct tgcggaattg gtcaaaatcg
     7681 atcctaagtc aattggtgtc ggtcaatacc aacacgatgt cagtcagaag aaactatctg
     7741 agagtctgga ctttgttgtc gatacagtgg ttaaccaagt tggtgtcaat gtcaatacag
     7801 ctagcccagc tcttctttca cacgtagctg gactcaacaa aactatctct gaaaatattg
     7861 tcaaataccg cgaggaagaa ggaaaaatca cttcacgcgc ccaaatcaag aaagttcctc
     7921 gtctgggagc caaggccttt gagcaggctg ctggtttcct tcgtatccct gaaagtagca
     7981 atatccttga taatacagga gttcacccag agaattacac tgcagttaag gaactcttca
     8041 aacgtttaga tattaaagac ctaaacgaag aagcccaaag caaactcaag tccctttcag
     8101 tcaaggaaat ggctcaagag ctagacctcg gtccagaaac ccttaaagat atcattgcag
     8161 atcttctcaa accaggtcga gatttccgtg attcctttga cgcacctgtg cttcgccaag
     8221 atgtcctaga tatcaaagac ctagtggtag gtcagaagct agaaggtgtt gtgcgtaacg
     8281 ttgttgactt cggtgccttc gttgatatcg ggattcacga ggacggcttg attcatattt
     8341 ctcatatgag tcgcaagttt atcaaacacc ctagtcaagt ggtgtcagtt ggagatttgg
     8401 tgaccgtttg ggtcaagaaa attgatactg aacgtgaaaa agttaatctg tcgctcctcg
     8461 ctccaaatga aactgactga ttatgtcaag caggtttcac tagaagactt cgggagagct
     8521 tttatccatc atgtccagtg gaataggcgt ctacgttcga caggtgggcg atttttcccc
     8581 aaagatgggc atctggattt taatcccaag gtttatcaga aactgggtat ggaggttttt
     8641 aggaaaattg tccgacatga actctgtcat tatcaccttt atttccaagg gaagggctat
     8701 caacacaagg atcgggattt taaggaactt ttgaaagcag tggatggatt aaggtttgta
     8761 ccatccttgc ccaatagtaa ctctaaacca ctcaagcttt atcgttgtca atcctgccag
     8821 caaaggtatc agcgcaagcg taggattgat acccaacgct atcgctgtgg actttgtcga
     8881 ggtaaattgc ttctgataaa tcagcctgag gactgatgaa agccgagcct ccccgtgata
     8941 tactatgtct aacctagcag aaagaggaaa tatcatgaac agtaaatttt ataaaatgag
     9001 acgcaatcgc atgatttcag gagttctggc aggtctgtca gacaagtgga attttgatgt
     9061 taccctagtt cgtttcttgt ttgccatttt tacagttgca aactttggac ttggcgtgat
     9121 tatctatatc atcctagctt ctatcatgcc taccaaggaa gaaatcgaag cagaaatgta
     9181 cggaacaggc ccacgtaaac gcaaagaagc ccaagccatt gacgacaatg aaggctggtt
     9241 ttggtgaggt tctacagaag atttggaata agcaaaaatc tttaaatcaa tagtctaaac
     9301 tgcttgattt aaagcttttt tacttttata ctcaataaaa atcaaagtgc aaactaggaa
     9361 gccagccaca ggctgtaatt tagtcggcaa tgtgaagttg acatagtttg cactttgatt
     9421 tttgaatagt attaataata tttcgccagc ttcatccaca aactatagtg gattggaact
     9481 agaatagtac acctctactt ctaaaacatt gttagaaatc gatttgacta tcctgatcga
     9541 tttgtcctgt tcttatttca ttttattata aaagcagtaa tttaaactca gttttttaat
     9601 ctatttttgc tgctgagaca atacattttt ggaaaaatgg tggatgctga taacaactga
     9661 taaccagcaa ataacataag cagtgccggt aaattctgta ccgataaagt gtgtgtgttc
     9721 aactaagagc tgaccgatga atggagagag cagatagaga agtccgatga gtatatgttc
     9781 tttgtgtttc attaaagcgc accttctttc cttataggtt gaacgacttg caagtgttaa
     9841 attgaatggt atgttatcta ggtaacctta ctaaaatgtt agttcccgct tcctcctttt
     9901 caaagtaagc cttttcacac ttatatttta caactttaaa aataggaaat caaatcattt
     9961 tctaagtaat tttgcttata tttcacccaa tcttacaaaa atgtaagatt aaagtctctt
    10021 ttgtaaggtt aggttatggc aagcggtctt tttttgatgt aaactagact cataaagaac
    10081 aaaggagtaa catcatgaaa caaatcttac ataagaaaac tagaaaacca agtcacaaag
    10141 aaattgagcg cgttcagctg ggatgcacta tgatgcaagc tacatttcat ttgatgggat
    10201 attaagaaag gagattctca tgacactttt agatgtaaaa cacgttcaaa aaatttataa
    10261 aacacgtttt cagggcaacc aagtagaggc cctcaaggat attcacttca ccgtagaaaa
    10321 gggtgactac gttgctatca tgggtgagtc tggttctggt aaatccactc tgctcaatat
    10381 cctagctatg ctggataaac caagtcgtgg gcaggtttac ctaaacggaa ctgatacagc
    10441 aactattaaa aattcacagg cttctagttt ccggcgtgaa aagctaggat ttgtcttcca
    10501 agactttaac ttgctagata ctctgtctgt taaggacaat atcttgcttc cgcttgtctt
    10561 gtcaagaaga cctataacgg agatgatgaa gaaattggtg atgacagctg aaaatctggg
    10621 tatcaaccaa ttgcaagaga agtaccctta cgagatttct ggtggtcaga aacagcgtgt
    10681 agcagtagcc cgcgccatca tcacagaacc tgaaattctc cttgcggacg agccaacagg
    10741 agcccttgat tccaagtcat ctgcagcctt acttgatgtc tttaatgaaa tcaatgagcg
    10801 tgggcaaacc atcctcatgg taacccactc aacagcagct gctagcaggg ccaagcgtgt
    10861 tctctttatc aaagacggca ttctttacaa tcaaatctac cgtggagaga agacagaacg
    10921 tcagatgttc caagaaatct ctgatacctt gactgtcatg gcaagcgagg tgaattagta
    10981 tgtttcgatt aaccaataag ttagcggtat cgaacttgat taaaaaccgc aaactctact
    11041 atccctttgc actggctgtt ctcttggcag tcaccatcac ctatctcttt tactccctaa
    11101 ccttcaatcc aaagattgcg gaaatccgtg gaggaaccac cattcaagca acacttggat
    11161 ttggtatgtt tgtcgttacc cttgcgtcag ccattatcgt cctctatgcc aatagttttg
    11221 tcatgaaaaa ccgttccaag gaactgggta tatatggcat gttaggcttg gagaagcgcc
    11281 atctaatcag tatgaccttt aaggagttag tgctatttgg gattctaact gttggagcag
    11341 gaatcggtat tggagccttg tttgacaagt tgattttcgc tttcctactc aaactgatga
    11401 aattgaaggt ggaactggtc gctaccttcc agatgaaagt tgtcattaca gtacttcttg
    11461 tcttcggttt gattttccta ggcctcatgt tcctgaatgc ccttcgaatc gcccgtatga
    11521 atgccctcca gctctcacgt gagaaagcta gcggagagaa aaaaggtcgc ttccttcctc
    11581 tccaaactat tcttggttcc ataagtttag ggattggata ttatcttgcc cttacggtaa
    11641 aagatcctct tacagcctta acaaccttct tcatagctgt tttactggtt atctttggta
    11701 cttatctttt gttcaatgca gggattaccg ttttccttca aatcttaaag aaaaataaga
    11761 aatactatta ccaacctaat aatctcatat ctgtttctaa cttgattttc cgtatgaaga
    11821 aaaatgcagt tggactagca actatcgcta ttttgtcaac aatggttttg gtaaccatgt
    11881 cagcagcgac aagcattttc aattccgcag aatcctttaa aaaagttcta aatcctcatg
    11941 attttggggt ttcagggcaa aatgttgaaa aagaagattt ggacaaactc ttgagccagt
    12001 ttgcaagtga caaaggttat aagattaaag agaaagaagt gcttcgttac acttactttg
    12061 ctgttgcgaa tcaagaagga accaagttaa ctatttttga aaaaggacaa aaccgtgtcc
    12121 aaccaaaaac agttttcatg gtatttgacc aaaaagatta tgaaaatatg actggtcaaa
    12181 aactgtctct atcaggaaat gaggtcggtc tctttgccaa aaatgacgga ctgaaaggac
    12241 agaaagctct aactctaaat gatcatcaat tttctgtcaa agaagaattt aataaagatt
    12301 tcattgtgaa ccatgttcca aataagttta atatcttgac tactgattac aattaccttg
    12361 ttgttcctga tttacaagcc tttttggatc aattcccaga ttcggctatc tataatcagt
    12421 tttacggtgg tatgaatgta gatgccagcg aagaagaaca actcaaggtc gctgaggagt
    12481 atgaaaacta cctcaatcaa tttaatgctc aattagacac agaaggtagc tatgtttatg
    12541 gtagcaatct agcagatgct agttctcaga tgagtgccct ctttggtggt gtcttcttta
    12601 tcggtatttt cctatccatt atctttatgg tcggaactgt tctggtcatc tactacaaac
    12661 aaatttctga aggctacgaa gaccgtgaac gctttattat cttgcagaaa gttggtttgg
    12721 accaaaagca aatcaagcaa accatcaaca aacaggtttt aactgttttc ttccttcctt
    12781 tgctctttgc cttcatacat ctcgcctttg cctaccatat gcttagcctg attttaaaag
    12841 tgattggtgt actggatacg actatgatgt tgattgtgac cttgtctatc tgcgctatct
    12901 tcctcatcgc ctatgtgctg attttcatga ttacttcaag aagttatcgc aagattgtgc
    12961 aaatgtaaaa aagatacctc gacttcaaaa tcgaggtatt tcttgtattc taaatgctga
    13021 aaagttgttc gagcaggaag gtaactccca tggtcaagag accaatagca aggttccgaa
    13081 tcatagctgt tctagtcgga tcctttccaa gtctggcact agtgtaacca gtgagaagaa
    13141 gggccacacc gacaataagg acagtagcag ggatgcggta atcacttgga aaaatggtca
    13201 ctgacagcat tggaggcaaa cttctaagga aaaaggcaac gaagctagaa atggcagcgt
    13261 gccaaggatt ggtaaattct tcatactcaa tcccatattt ttcctctacc agagccttga
    13321 gtggattttt aagaaagatc ttattggtca agagttgggc agaagttttg cattctccat
    13381 tttggatata agcagcatcg agggattttt tggctagttc cctatcttgg tctaacaaga
    13441 gtttttctcg cgaaacggca gcttcctcgg tatcttttgg agttgaaacg gatacatatt
    13501 ctccaccagc cattgaaaag gcaccagcta agatagccgc aaatcctgat aaaaagataa
    13561 tccagatatt ggtcgtggca ctggcaaccc cgataaccac accagcaatg gaaataattc
    13621 catcgttagc accaagaaca cctgcgcgca ggatatttaa acgacctgca aaatttgaat
    13681 cgatttcgtg atttgtttct ga
//
LOCUS       DAVBOD010000051        13339 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 640-05
            SAMEA1012484-rid20186543.denovo.051, whole genome shotgun sequence.
ACCESSION   DAVBOD010000051 DAVBOD010000000
VERSION     DAVBOD010000051.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012484
            Sequence Read Archive: ERR059358
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 13339)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13339)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979948.1
            Genome Coverage       :: 595x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:03:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,266
            CDSs (total)                      :: 2,219
            Genes (coding)                    :: 2,091
            CDSs (with protein)               :: 2,091
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 71 of 128
            Pseudo Genes (incomplete)         :: 50 of 128
            Pseudo Genes (internal stop)      :: 33 of 128
            Pseudo Genes (multiple problems)  :: 22 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13339
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012484-rid20186543.denovo.051"
                     /strain="NIG 640-05"
                     /db_xref="taxon:1313"
     gene            89..1027
                     /gene="msrB"
                     /locus_tag="VQ862_001667"
     CDS             89..1027
                     /gene="msrB"
                     /locus_tag="VQ862_001667"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HET3115977.1"
                     /translation="MAEIYLAGGCFWGLEEYFSRISGVLETSVGYANGQVETTNYQLL
                     KETDHAETVQVIYDEKEVSLREILLYYFRVIDPLSINQQGNDRGRQYRTGIYYQDEAD
                     LPAIYTVVQEQERMLGRKIAVEVEQLRHYILAEDYHQDYLRKNPSGYCHIDVTDADKP
                     LIDAANYEKPSQEVLKASLSEESYRVTQEAATEAPFTNAYDQTFEEGIYVDITTGEPL
                     FFAKDKFASGCGWPSFSRPISKELIHYYKDLSHGMERIEVRSRSGSAHLGHVFTDGPR
                     ELGGLRYCINSASLRFVAKDEMEKAGYGYLLPYLNK"
     gene            1085..2809
                     /locus_tag="VQ862_001668"
     CDS             1085..2809
                     /locus_tag="VQ862_001668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3115978.1"
                     /translation="MKHLLSYFKPYIKESILAPLFKLLEAVFELLVPMVIAGIVDQSL
                     PQGDQGHLWMQIGLLLIFAVIGVLVALIAQFYSAKAAVGFAKELTNDLYRHILSLPKD
                     SRDRLTTSSLVTRLTSDTYQIQTGINQFLRLFLRAPIIVFGAIFMAYRISAELTFWFL
                     VMVAILTIVIVGLSRLVNPLYSSLRKKTDQLVQETRQQLQGMRVIRAFGQEKRELQIF
                     QTLNQVYARLQEKTGFLSSLLTPLTYLIVNGTLLVIIWQGYISIQGGVLSQGALIALI
                     NYLLQILVELVKLAMLINSLNQSYISAKRIEEVFAESPENIHSELEQKQVTSGRVLQV
                     QELTFTYPDAAQPSLRDISFDMTQGQILGIIGGTGSGKSSLVQLLLGLYPVDKGNIDL
                     YQNGRSPLNLEQWRSWIAYVPQKVELFKGTIRSNLTLGLNQEVTDQELWQALEIAQAK
                     DFVSDKEGLLDALVEAGGRNFSGGQKQRLSIARAVLRQAPFLILDDATSALDTITESK
                     LLKAIRENFPNMSLILISQRTSTLQMADQILLLEKGELLAVGKHDDLMKSSQVYREIN
                     ASQHGKED"
     gene            2811..4559
                     /locus_tag="VQ862_001669"
     CDS             2811..4559
                     /locus_tag="VQ862_001669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000828810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3115979.1"
                     /translation="MKRQTVNQTLKRLVVDLANHPFLLFLAFLGTIAQVGLSIYLPIL
                     IGQVIDQVLVAGSSPVFWQIFLQMLLVVIGNTLVQWANPLLYNRLIFSYTRDLRERII
                     HKLHRLPIAFADRQGNGEMVSRVTTDIEQLAAGLTMIFNQFFIGVLMILVSILAMLQI
                     HLLMTLLVLLLTPLSMVISRFIAKRSYHLFQKQTETRGIQTQLIEESLSQQTIIQSFN
                     AQTEFIQRLREAHDNYSGYSQSAIFYSSTVNPSTRFVNALIYALLAGVGAYRIMMGST
                     LTVGRLVTFLNYVQQYTKPFNDISSVLAELQSALACVERIYGVLDSPEVAETGKEVLT
                     SDQVKGAISFKHVSFGYHPEKILIKELSIDIPAGSKVAIVGPTGAGKSTLINLLMRFY
                     PISSGDILLDGQSIYDYTRVSLRQQFGMVLQETWLTQGTIHDNIAFGNPEVSREQVIA
                     AAKAANADFFIQQLPQGYDTKLENAGESLSVGQAQLLTIARVFLAIPKILILDEATSS
                     IDTRTEVLVQDAFAKLMKGRTSFIIAHRLSTIQDADLILVLVDGDIVEYGNHQELMDR
                     KGKYYQMQKAAAFSSE"
     gene            4816..6075
                     /locus_tag="VQ862_001670"
     CDS             4816..6075
                     /locus_tag="VQ862_001670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRZ/ATZ family protein"
                     /protein_id="HET3115980.1"
                     /translation="MKVFQHVNIVTCDQDFHVYLDGILAVKDSQIVYVGQDKPAFLEQ
                     AEQIIDYQGAWIMPGLVNCHTHSAMTGLRGIRDDSNLHEWLNDYIWPAESEFTPDMTT
                     NAVKEALTEMLQSGTTTFNDMYNPNGVDIQQIYQVVKTSKMRCYFSPTLFSSETETTA
                     ETISRTRSIIDEILKYKNPNFKVMVAPHSPYSCSRDLLEASLEMAKELNIPLHVHVAE
                     TKEESGIILKRYGKRPLAFLEELGYLDHPSVFAHGVELNEREIERLASSQVAIAHNPI
                     SNLKLASGIAPIIQLQKAGVAVGIATDSVASNNNLDMFEEGRTAALLQKMKSGDASQF
                     PIETALKVLTIEGAKVLGMENQIGSLEVGKQADFLVIQPQGKIHLQPQENMLSHLVYA
                     VKSSDVDDVYIAGEQVVKQGQVLTVEL"
     misc_feature    6151..6286
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00557"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L10 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00557"
     gene            6325..6825
                     /locus_tag="VQ862_001671"
     CDS             6325..6825
                     /locus_tag="VQ862_001671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001287276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L10"
                     /protein_id="HET3115981.1"
                     /translation="MSEAIIAKKAELVDVVAEKMKAAASIVVVDARGLTVEQDTVLRR
                     ELRGSEVEYKVIKNSILRRAAEKAGLEDLASVFVGPSAVAFSNEDVIAPAKILNDFSK
                     NAEALEIKGGAIEGAVASKEEILALATLPNREGLLSMLLSVLQAPVRNVALAVKAVAE
                     SKEDAA"
     gene            6901..7269
                     /gene="rplL"
                     /locus_tag="VQ862_001672"
     CDS             6901..7269
                     /gene="rplL"
                     /locus_tag="VQ862_001672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L7/L12"
                     /protein_id="HET3115982.1"
                     /translation="MALNIENIIAEIKEASILELNDLVKAIEEEFGVTAAAPVAVAAA
                     DAADAGAAKDSFDVELTSAGDKKVGVIKVVREITGLGLKEAKELVDGAPALVKEGVAT
                     AEAEEIKAKLEEAGASVTLK"
     gene            7456..7629
                     /locus_tag="VQ862_001673"
     CDS             7456..7629
                     /locus_tag="VQ862_001673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001168336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3115983.1"
                     /translation="MQKKGQSSRQFVKSHLMTIMGVDIVKATQLVDEMEQVGLIRFDE
                     FGNVEILVLEGQS"
     gene            7626..8222
                     /locus_tag="VQ862_001674"
     CDS             7626..8222
                     /locus_tag="VQ862_001674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000822799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HET3115984.1"
                     /translation="MKRITASQYQTSERYYKLPKLLFESERYKNMKLEVKVAYSILKD
                     RLELSLNSGWIDEEGAVYLVFSNSKLMKLLGCSKSKLLSIKKTLREYGLIDEVQQSSS
                     EKGRMANKIYLGELEHEIPLVLHSDGASVKNRLGQSQKQTGPFLNSAPSETEESETDS
                     LFIEDEEERDTQPILKRKVEKVTKYDRDYIWGLVQDQF"
     gene            8259..8396
                     /locus_tag="VQ862_001675"
     CDS             8259..8396
                     /locus_tag="VQ862_001675"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3115985.1"
                     /translation="MTDFERIYQYALDNVRFVRRAEVLAEFVFNGLYSVWNNRVRKGG
                     G"
     gene            8495..9894
                     /gene="dcm"
                     /locus_tag="VQ862_001676"
                     /pseudo
     CDS             8495..9894
                     /gene="dcm"
                     /locus_tag="VQ862_001676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014947343.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA (cytosine-5-)-methyltransferase"
     gene            9878..10327
                     /locus_tag="VQ862_001677"
     CDS             9878..10327
                     /locus_tag="VQ862_001677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000645893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3115986.1"
                     /translation="MKALNKESILDCDELETELHDAEIKQLDEQLFLMPNYPCEFEVT
                     FLDDYHKKHNYPLFYESYLQNVMEFLESQDIKNGVDAFVDDHQNLVFVLYGQGYRAEG
                     KEGILTTQVTVKAYDEDKKPINFANLLDSLIVSEYQMEPNLWKVSHD"
     gene            10320..10700
                     /locus_tag="VQ862_001678"
     CDS             10320..10700
                     /locus_tag="VQ862_001678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3115987.1"
                     /translation="MIDLYLSKNSQRNQLLLDFFQKYGIEVTPHSISEMTKDKLIEMM
                     SYSSDCFEFLSPNLLRFKNRDNLRLTDFIEMILKNPELCIRLPLAVSNKRVYPNLNLE
                     EARALLPRDTKQLIYMAQTHYLSS"
     gene            10713..10946
                     /locus_tag="VQ862_001679"
     CDS             10713..10946
                     /locus_tag="VQ862_001679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HET3115988.1"
                     /translation="MAERFWENLSIILAERNISWIELTRKMFAGEFHYPSELNRLYQK
                     IRHYKMEQRMPQSPWVERIVQVLDLDYEDLFRR"
     gene            10949..11536
                     /locus_tag="VQ862_001680"
     CDS             10949..11536
                     /locus_tag="VQ862_001680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000821312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET3115989.1"
                     /translation="MKRIIPVYIFQQVNVLLVSLYLLKLLCIGELTILQILYCASLIS
                     FLWMYGQRKQVVKVNMKTRMKWLGIGFVSLLIISLCFSLIHAQGTTNQANLIGLQHQV
                     PWFSFLLFLINASMVEEFLYREILWNLVRKLDIRVALTSVLFALVHHPGTILAWCLYV
                     SLGIFLGMVRYKSDLWGSMGLHLVWNLSVYVLFFL"
     gene            11666..12256
                     /locus_tag="VQ862_001681"
     CDS             11666..12256
                     /locus_tag="VQ862_001681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000227923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV toxin-antitoxin system AbiEi family
                     antitoxin domain-containing protein"
                     /protein_id="HET3115990.1"
                     /translation="MVDKREKLMNSFNQYGFLTFKQVIDENLHYKTLLKMVTEGKIDA
                     EEKGLYRLPDIYLDEWFVIQYRFPKGIFSLETALWLHGLSLTIPFNMTMSFPYGTNTK
                     NIKEADICPIILRSHYSEGIIEIERLPGQFIKVYEIERVLVECLRPVHQVDLQIIAPA
                     FKKYFQQNQIHLHKLFYYAQLFKVTDKLQSYTEVLS"
     gene            12256..13092
                     /locus_tag="VQ862_001682"
                     /pseudo
     CDS             12256..13092
                     /locus_tag="VQ862_001682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000492399.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyl transferase AbiEii/AbiGii toxin
                     family protein"
BASE COUNT         4144 a         2366 c         2840 g         3989 t
ORIGIN      
        1 aaccatacct acggtaaggt gacgctgacg tggtttgaag agattttcga agagtattag
       61 ttaaaaacgt gataaaggag aaataaaaat ggcagaaatt tatctagcag gtggttgttt
      121 ttggggccta gaggaatatt tttcacgcat ttctggagtg ctagaaacca gtgttggcta
      181 cgctaatggt caagtcgaaa cgaccaatta ccagttgctc aaggaaacag accatgcaga
      241 aacggtccaa gtgatttacg atgagaagga agtgtcactc agagagattt tactttatta
      301 tttccgagtt atcgatcctc tatctatcaa tcaacaaggg aatgaccgtg gtcgccaata
      361 tcgaactggg atttattatc aggatgaagc agatttgcca gctatctaca cagtggtgca
      421 ggagcaggaa cgcatgctgg gtcgaaagat tgcagtagaa gtggagcaat tacgccacta
      481 cattctggct gaagactacc accaagacta tctcaggaag aatccttcag gttactgtca
      541 tatcgatgtg accgatgctg ataagccatt gattgatgca gcaaactatg aaaagcctag
      601 tcaagaggtg ttgaaggcca gtctatctga agagtcttat cgtgtcacac aagaagctgc
      661 tacagaggct ccatttacca atgcctatga ccaaaccttt gaagagggga tttatgtaga
      721 tattacgaca ggtgagccac tcttttttgc caaggataag tttgcttcag gttgtggttg
      781 gccaagtttt agccgtccga tttccaaaga gttgattcat tattacaagg atctgagcca
      841 tggaatggag cgaattgaag ttcgttctcg ttcaggcagt gctcacttgg gtcatgtttt
      901 cacagatgga ccgcgggagt taggcggcct ccgttactgt atcaattctg cttctttacg
      961 ctttgtggcc aaggatgaga tggaaaaagc aggatatggc tatctattgc cttacttaaa
     1021 caaataaaac agagagtggg gcttcccact ttcttcattt ctagaatatg aatagaaggg
     1081 atttatgaaa cacctattat cttacttcaa accctacatc aaggaatcaa ttttagcccc
     1141 cttgttcaag ctgttagaag ctgtttttga gctcttggtt cccatggtga ttgctgggat
     1201 tgttgaccaa tctttacctc agggagatca aggtcatctc tggatgcaga ttggcctgct
     1261 ccttatcttt gcagtaattg gcgttttagt ggccttgata gctcaatttt actcagcaaa
     1321 ggcagcagta ggttttgcta aggaattgac aaacgatctt tatcgtcata ttctttcctt
     1381 gccaaaggac agcagagacc gtctgacaac ttctagtttg gttactcgct tgacttcgga
     1441 tacctaccag attcagactg gtatcaatca attcctgcgt ctctttttac gagcgcccat
     1501 tatcgttttt ggtgccattt ttatggctta tcgaatctca gctgagttga ctttctggtt
     1561 cttagtcatg gttgccattt tgaccattgt cattgtaggg ttatctcgat tggtcaatcc
     1621 tctctacagt agtctcagaa agaaaacgga ccaactggtt caggaaacgc gccagcaatt
     1681 gcaagggatg cgggttattc gtgcttttgg tcaagaaaaa cgagagttac agatttttca
     1741 aacccttaac caagtttatg ctagattaca agaaaagaca ggtttcttgt ctagtttatt
     1801 aacacctctg acctatctga ttgtcaatgg aactcttctc gttattatct ggcaaggcta
     1861 tatttcaatt caaggaggag tactcagtca aggtgctctc attgctctta tcaattacct
     1921 cttacagatt ttggtggaat tggtcaagct agccatgctg atcaattccc tcaaccagtc
     1981 ctatatctca gccaagagaa tcgaggaggt ctttgcggaa tctcccgaaa acatccattc
     2041 agaattagaa caaaagcaag ttaccagtgg tcgggtttta caagtccaag aattgacttt
     2101 tacctatcct gatgcggccc agccttctct gagagacatt tcctttgata tgactcaagg
     2161 acaaatcctt ggtatcattg gggggactgg ttctggtaaa tcaagcttgg tgcaactctt
     2221 acttggactt tatccagtag acaaggggaa cattgacctt tatcaaaatg gacgtagtcc
     2281 tcttaatttg gagcagtggc ggtcttggat tgcctatgta cctcaaaagg tcgaactctt
     2341 taagggaact attcgttcca acttgacttt aggtttaaat caagaagtga ctgatcaaga
     2401 actctggcaa gccttggaga ttgcgcaagc taaggatttt gtcagtgata aggaaggact
     2461 cttggatgct ctagttgaag caggagggcg aaatttctca ggtggacaaa aacaaaggct
     2521 gtctatcgca cgagcagtct tgcgccaggc tccgtttctc atcctagatg atgcgacctc
     2581 agcactggac accattacag agtccaagct cttgaaagct attagagaaa attttccaaa
     2641 catgagctta attttgatct ctcaacgaac ctcgacttta cagatggcgg accagattct
     2701 cctcttggaa aaaggtgagt tgctagctgt tggcaagcac gatgacttga tgaaatccag
     2761 tcaagtctat cgtgaaatca atgcatccca acatggaaag gaggactaga atgaaacgac
     2821 aaactgtaaa ccagacgctc aaacgtttag tcgtagattt agcaaaccat cccttcctcc
     2881 ttttcctagc ctttctagga actattgccc aagttggctt atcaatttac ctacctattc
     2941 tgattgggca ggtcattgac caagtcctag tggctggttc atcaccagtt ttttggcaga
     3001 tttttctcca gatgctcttg gtggtaatag gaaatactct ggtacaatgg gccaatcctc
     3061 tcctctataa tcgtctaatc ttctcttata ccagagattt acgagagcga atcatccata
     3121 aactccatcg gttaccgatt gcttttgcgg atcggcaagg caatggagag atggtcagtc
     3181 gtgtaaccac ggatatcgaa cagttggcag ctggcttgac catgattttt aaccaatttt
     3241 tcattggtgt tttgatgatt ttggttagta ttctagccat gctccaaatt catctcctca
     3301 tgactctctt agtcttgctg ttgacgccac tgtccatggt gatttcacgc tttattgcca
     3361 agagatccta tcatctcttc cagaagcaaa cagagacgag gggaattcag actcagttga
     3421 ttgaagaatc gcttagccag cagactataa tccagtcctt caatgctcaa acagaattta
     3481 tccaaagatt gcgtgaggct catgacaact actcaggcta ttctcagtca gccatctttt
     3541 attcttcaac ggtcaatcct tcgactcgct ttgtaaatgc actcatttat gcccttttag
     3601 ctggagtagg agcttatcgt atcatgatgg gttcaacctt gaccgtcggt cgtttagtga
     3661 cttttttgaa ctatgttcag caatacacca agccctttaa cgatatttct tcagtgctag
     3721 ctgagttgca aagtgctctg gcttgcgtag agcgtatcta tggggtctta gatagccctg
     3781 aagtggctga aacaggtaag gaagtcttga ccagtgacca agttaaggga gctatttcct
     3841 ttaaacatgt ctcttttggc taccatcctg aaaaaatttt gattaaggag ttgtctatcg
     3901 atattccagc tggtagtaag gtagccatcg ttggtccgac aggtgctgga aaatcaactc
     3961 ttatcaatct ccttatgcgt ttttatccca ttagctcggg agatatcttg ctggatgggc
     4021 aatccattta tgattataca cgagtatcat tgagacagca gtttggtatg gtgcttcaag
     4081 aaacctggct cacacaaggg accattcatg ataatattgc ctttggcaat cctgaagtca
     4141 gtcgagagca agtaattgct gctgccaaag cagctaatgc agactttttc atccaacagt
     4201 tgccacaggg atacgatacc aagttggaaa atgctggaga atctctctct gtcggccaag
     4261 ctcagctctt gaccatagcc cgagtctttc tggctattcc aaagattctt atcttagacg
     4321 aggcaacttc ttccattgat acacggacag aagtgctggt acaggatgcc tttgcaaaac
     4381 tcatgaaggg ccgcacaagc ttcatcattg ctcaccgttt gtcaaccatt caggatgcgg
     4441 atttaattct tgtcttagta gatggtgata ttgttgaata tggtaaccat caagaactca
     4501 tggatagaaa gggtaagtat taccaaatgc aaaaagctgc ggcttttagt tctgaataag
     4561 ccattctctt ttgaaagttt atggacgaaa aaagttgcct tcgagtgact tttttgttac
     4621 aatagctaga aaaattgttc actgtaatac tcaatgaaaa ttaaagagca aactaggaag
     4681 ctagccgtag gttgctcaaa acactgtttt gaggttgcag atagaactga cgaagtcagt
     4741 aaccacacct acggcaaagt gaatctgaag tggtttgaag agagtacaac ttgtctttta
     4801 gaaaaggagc ctataatgaa agtctttcag catgtaaata tcgtgacttg tgatcaagat
     4861 ttccatgttt atcttgatgg aatcttagca gtcaaggatt ctcaaatcgt ctatgtcggt
     4921 caagataagc cagcgttttt agagcaagct gagcagatta tagactatca gggagcttgg
     4981 attatgcctg gtttggtcaa ttgtcacacc cattctgcaa tgacaggtct gagagggatc
     5041 cgagatgaca gcaatctcca tgaatggctc aatgactata tctggccagc agaatctgag
     5101 tttactcccg acatgactac caatgcggtc aaagaagccc taacagagat gctccagtca
     5161 ggaacaacaa cctttaacga tatgtataat cccaatggtg tggatatcca gcaaatttat
     5221 caggtggtga aaacttccaa gatgcgttgt tatttttctc cgactctctt ttcttcagag
     5281 acagaaacaa ctgctgagac tataagcaga actcgatcca tcatagatga aatcttaaaa
     5341 tataaaaatc caaatttcaa ggttatggta gcacctcatt ctccgtatag ctgcagtaga
     5401 gacttgctgg aagcgagttt ggaaatggca aaagagctaa atattccgct ccatgtccat
     5461 gtggcggaga ccaaggagga gtcaggaatt atcctcaaac gatacggcaa acgccccctt
     5521 gcttttcttg aagaactggg ttatttagat catccgtccg tatttgctca cggggtcgaa
     5581 ttaaacgaga gagaaattga acgcttggca tcttctcaag tggctatcgc ccacaatcct
     5641 atcagtaacc tcaaactggc atcaggaatt gctccaatta tccagctcca aaaagcggga
     5701 gtagcagtcg gaattgcgac tgactcggtt gcttccaata acaatctaga tatgtttgag
     5761 gaaggaagga ctgcagctct tcttcagaag atgaaaagtg gggatgccag ccagtttcca
     5821 atcgaaacag ctctcaaggt actgacaatc gaaggggcta aggtccttgg aatggaaaat
     5881 cagataggaa gtctggaagt cggcaagcaa gcagattttc tggtcattca accacaaggg
     5941 aaaattcatc tccaacctca ggaaaatatg ctgtctcacc tggtttatgc agttaaatct
     6001 agtgatgtag atgatgttta tatcgccgga gaacaggttg ttaagcaagg tcaagtcctg
     6061 acagtagaac tttaaaagaa aaatcacgaa aaattttaaa aaaagtttgc aaaaatcttg
     6121 cattcttttt ttgactatgc tatacttata tacggtttaa aaaaactgcc taagacagta
     6181 ggggagctcg actcataaat atcctaccga ggacaaaacg tatcatgtaa aaagaagcgt
     6241 attgtacttt cgtgtctagg tttgggcgcg tttttctttt tgaaaaattc cccaagcaaa
     6301 ataattacgg aggtgaacac actaatgagt gaagcaatta ttgctaaaaa agcggaacta
     6361 gttgacgtag tagctgaaaa aatgaaagct gctgcatcta tcgtcgttgt agacgctcgt
     6421 ggtttgacag ttgagcaaga tacagttctt cgtcgtgagc ttcgtggaag cgaagttgag
     6481 tataaagtta ttaaaaactc aatcttgcgt cgtgcagctg aaaaagctgg tcttgaagat
     6541 cttgcatctg tatttgttgg accatctgca gtagcatttt ctaatgaaga tgttatcgca
     6601 ccagcgaaaa tcttgaacga cttttctaaa aacgctgaag cacttgaaat taaaggtggt
     6661 gcaatcgaag gcgctgtcgc atctaaagaa gagattcttg cacttgcaac tcttccaaac
     6721 cgcgaaggac ttctttctat gctcctttct gtacttcaag cgccagtgcg caacgttgct
     6781 cttgcagtca aagcggttgc agaaagcaaa gaagacgcgg cttaatctta agctacacag
     6841 cgtagcctag ctacgaaaaa aactattata aaatttaaaa cttatttgga ggaaataaca
     6901 atggcattga acattgaaaa cattattgct gaaattaaag aagcttcaat ccttgaattg
     6961 aacgaccttg taaaagctat cgaagaagaa tttggtgtaa ctgcagctgc tcctgtagct
     7021 gttgctgcag ctgatgcagc tgatgctggt gctgctaaag attcattcga cgttgaattg
     7081 acatctgcag gcgacaaaaa agttggcgtt atcaaagttg tacgtgaaat tactggtctt
     7141 ggtcttaaag aagctaaaga acttgttgac ggtgcaccag cacttgttaa agaaggcgtt
     7201 gcaactgcag aagctgaaga aatcaaagct aaattggaag aagctggagc ttcagttact
     7261 cttaaataat agagtatcgc aatttaattg cggaatccct atttaccagt ctttgagagc
     7321 gataagcgat tgatagaaac tgataaattg atttggtttc ctgccaaaaa ttctttggca
     7381 ggatttttgt tttaataaac tttcgggggt agacactaga ttgtctaccc ctttttttgt
     7441 gtttcggagg taattatgca aaagaaagga cagtcatcac gtcaattcgt gaagagtcat
     7501 ctcatgacta tcatgggagt tgatattgta aaagcaactc agttagttga tgaaatggaa
     7561 caagtaggtt taatccgatt tgatgaattt ggaaatgttg aaattttagt cttggaggga
     7621 caatcatgaa gcgtattacc gctagtcaat atcagacatc agagcgttat tataagctcc
     7681 ccaaactttt atttgagagt gaacggtata agaatatgaa actagaagta aaggtggctt
     7741 attctatttt aaaagatcgt ttagaattat ctctcaatag tggttggata gatgaagaag
     7801 gggcggtcta tttagtattt tctaactcta aactgatgaa gcttttaggc tgttcaaagt
     7861 caaaattact ctccatcaag aaaactttac gtgagtatgg cctaattgat gaagtccaac
     7921 agtcttccag tgaaaaaggt cgtatggcta ataaaattta cttaggggaa ttagaacatg
     7981 agatacccct agtcttacat tcagacgggg ctagtgttaa aaacagatta gggcagtctc
     8041 aaaaacagac ggggccgttt ttaaattcag cccctagtga gactgaagaa agtgagactg
     8101 attctttatt tattgaggat gaggaggaga gggatactca acctatcttg aaaagaaaag
     8161 tagaaaaggt cacaaaatat gatcgagatt atatttgggg attggtacaa gatcaatttt
     8221 gacgagaggg gttttctgaa acagccagtg aaattgctat gactgatttt gagagaatct
     8281 atcagtatgc tcttgacaat gttcgctttg ttagacgagc ggaagtactt gctgaatttg
     8341 tgtttaacgg cctatattct gtttggaata accgtgttag aaaaggaggt ggttaaatgt
     8401 cgccaatcga gtggatatta gttatgctca ttttaatttc aagtggtgtg acactttgga
     8461 cattgatagt tgatcagaaa ggggtaatca agaaatgaga tttattgatt tattttcagg
     8521 tatcggtggt tttcgacttg gaatggaaag tgtcggacac gagtgtattg gattttgtga
     8581 gattgataaa tttgctagag aatcttataa gtccattttt caaacggaag gagaaataga
     8641 atatcatgac attaaagagg taacagatca tgactttaga caatttagag ggcaagtgga
     8701 catcatctgc gggggatttc cttgccaagc tttttcactt gcaggaagac gattgggatt
     8761 tgaagatact agaggaactt tgttctttga aattgctcgg gcggccaaac aaatccaacc
     8821 acgttttctt tttcttgaaa atgttaaagg cctactcaat cacgataagg gacggacgtt
     8881 caccacaatc cttaccacat ttgatgagtt ggggtttgat gttgagtggc aggtgcttaa
     8941 cagtaaggat tttggcgttc cccaaaacag agagagggtg tttattatcg gacattctag
     9001 aaagaaaggt accagactct tatttccttt cagacgagaa ggtcaagcaa ctaactctga
     9061 gactttgaaa gcactaggaa atttgaatcc atcaaaaagt ggcgtgagcg gtaaagtgta
     9121 ttattcagaa ggtcttgcgc caactttagt tcgtggaaaa ggagaaggat ttaaggttgc
     9181 tattccttgt atgacaccag atagattaga caaaagacaa aatggtagac gctttaagga
     9241 aaaccaagag ccgatgttta ctttaaatac tcaggatcgt catggcattg tcgttgttgg
     9301 agatttaccg actagtttta aggagacagg ccgtgtctat ggaagtgagg gcttatctcc
     9361 aacactgact acgatgcaag gaggagataa aatccccaaa atactaattc cagaaccaat
     9421 ccaatttcta aaagtacggg aagcaacgaa aaaaggatat gctcaagcag agattgggga
     9481 ttcaatcaat ttggaaagac caagttctca gtatcgtcgt ggtagagttg gcaaaggtat
     9541 agctaatacg ttaacaactg tggtagagtt ggcaaaggta tagctaatac gttaacaact
     9601 agtggtcaaa tgggagtagt agtggctagc tatgaaggag aagataaaca agtttaccaa
     9661 gtagctggtg ttttaataga tggacaattt taccgtttga gaatacgacg aatcactcct
     9721 aaagagtgtt ttcgattgca tggctttcct gattgggctt ttgaagctgc tagaaaagtc
     9781 tctagtaata gtcagctcta taaacaagct ggtaatagtg taaccgttcc tgtgattgcc
     9841 gcaatcgcaa agaaattaaa agaaatagag gaaaaagatg aaagcattaa ataaagaatc
     9901 aatactagat tgtgatgaat tagaaacaga attacatgat gcagaaatca aacagctgga
     9961 tgaacaatta tttttgatgc ccaattatcc atgtgagttt gaagtaacat ttttagatga
    10021 ttaccataaa aaacacaact acccactatt ttacgagtcc tatcttcaaa acgttatgga
    10081 attccttgaa agtcaagaca taaagaatgg ggttgatgcc tttgtagatg atcatcaaaa
    10141 tctcgttttt gttttatatg gacaaggcta tcgagcagag ggaaaagagg gaatacttac
    10201 aactcaagta actgtaaaag cttatgatga agacaagaaa ccgattaact tcgcaaattt
    10261 attagattcc ttaatcgtct cagaatatca aatggaaccg aatctttgga aggtctccca
    10321 tgattgatct ctatctaagt aaaaatagcc aaagaaatca acttcttttg gatttctttc
    10381 aaaagtatgg catagaggtc actcctcatt ctatttctga aatgacaaag gacaaattaa
    10441 ttgaaatgat gagctattct tcagattgtt ttgagtttct atctcccaat ttattacgat
    10501 ttaagaaccg tgacaatcta agattaacgg atttcattga aatgatatta aaaaatcctg
    10561 aactatgcat caggcttcct cttgcggttt caaataagag agtttatcca aatctgaatt
    10621 tggaagaggc tagagctcta ttgccaagag atacgaaaca attgatttac atggcacaaa
    10681 cacattattt atctagttaa aggagaagca atatggctga acgattttgg gagaacttgt
    10741 ccattatttt ggctgaaaga aatattagct ggattgagtt aaccagaaaa atgtttgcgg
    10801 gagagtttca ctatccaagt gaattgaatc gtttgtatca aaagatacgc cactacaaga
    10861 tggaacaacg aatgcctcaa agtccatggg tagaaaggat tgtgcaggta ttagatttag
    10921 attatgaaga tttatttcgg aggtaactat gaaaagaata attccagttt atatattcca
    10981 acaagtaaat gtcttattgg tatccctata cttactgaaa ttgctttgta ttggtgagtt
    11041 aaccatacta cagattctct attgtgcgtc gctcatttct tttttatgga tgtatggtca
    11101 acgaaaacaa gtggtcaagg tcaatatgaa aactaggatg aaatggcttg gtattggatt
    11161 cgttagccta ctgattataa gcctatgttt tagtctgatt catgctcaag gaaccacgaa
    11221 tcaagcaaac ttaattggcc ttcaacatca ggttccttgg ttttcatttt tattgttctt
    11281 aatcaatgcg agtatggttg aagaatttct gtatcgagaa attttatgga acttggtcag
    11341 aaaattagat attcgagttg ctttgacaag tgttttattt gccttagtac atcatccagg
    11401 aaccattcta gcttggtgtt tatatgtttc acttgggatc tttttaggga tggtgcgcta
    11461 taaatcggac ttatggggaa gtatgggtct acatttggtg tggaacctat cagtctatgt
    11521 cttatttttt ctttaataat agctggtctg tcttacgtat ggattaattt tgaaataaaa
    11581 aaactaaatg aattgatttt aaagaaataa aatgctaaca tatatagaag atgttagcat
    11641 tttatttcta agaaaggaga atggtatggt tgataaaaga gagaaactga tgaactcttt
    11701 caatcagtat ggttttttaa cttttaaaca agtaatagat gaaaatttac actacaaaac
    11761 cttattaaaa atggttacag aaggaaaaat cgatgctgaa gaaaaagggt tatatcgctt
    11821 acctgatatt tatttagatg agtggtttgt cattcagtat cgatttccaa aaggaatctt
    11881 ttctttggag acagcacttt ggttacatgg tttatctttg actatccctt ttaacatgac
    11941 aatgagtttt ccttatggta cgaataccaa aaacattaag gaagcagata tatgtcctat
    12001 tatcttacgc tctcactata gtgaaggaat tattgaaata gagcgtcttc ctggtcaatt
    12061 tattaaagtt tatgaaattg aacgagtttt ggttgaatgt ctaagaccag ttcatcaggt
    12121 ggatcttcaa attattgcac cagcgtttaa gaaatatttt caacagaatc aaattcattt
    12181 acacaaatta ttttattatg cccaactatt taaagtaact gataagttac aatcttatac
    12241 ggaggtgcta tcttaatgtt ttcaaatgcg aatagcttta aagcaaaaat caaaaatatt
    12301 tcaaaagata agggaattcc agctcaacaa gtacaacaac attatttaat tgagcaagtg
    12361 ttaaagctga tttctactag ttcttataga gattccttca ttgtaaaagg agggtatcta
    12421 ataggtcaaa tgattggact agataagcga accacaatgg atttagatgt cactctgaag
    12481 ggaaccgaaa tgagcagaga aaatttgatt gatatctttg aagagattct ttgttctaaa
    12541 actgatggtt tttcattttc agtagataag ctagaaccta ttcgccaaga tgatgaatat
    12601 ggaggatttt cattaaaata aaatgcaact tttgatacat taaaggaggt tgtttttatt
    12661 gatattacta ctggtgataa gatcacacca agagaaatta cttattcaat gacttctatc
    12721 tttactaatg aaagcatcaa gatatggaca tataatctag aaactgtact tgctgaaaag
    12781 ttagaaacaa tcattagtag gggattagct tcaacacgcc cacgtgatcg atatgatctt
    12841 ttcaccttgt ataaacttag aaaagaagag attaatcttg aagtattaaa aaatgcactt
    12901 gaaaatacag caaaaaaacg taaaagtaaa gatactattt ataattggga agaacaagtg
    12961 agaggaattg aaatttctga ttatcagaaa gagctatgga ttcgttatca acgccaattt
    13021 aagtatgcta aagatatctc atttgataac tctgttcagg ttattaggga aattatgcaa
    13081 caaatatttt agtacaaaag taactcattc gtaaagcagt gagttgcttt ttttattcca
    13141 acaacctcaa acatgtgata aaaatttcaa ctactcttat ctataataaa gctacctgtt
    13201 ctttgaaaat tgaatccact ccgtcttgat tagcgtgcct gtgtaagtag ggaatgagag
    13261 tatttccctg tgaagggcaa ctggcacaag acgtgtgtga gaattttcta acagacacgg
    13321 agtttatcgt ttccagact
//
LOCUS       DAVBOD010000052        13168 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 640-05
            SAMEA1012484-rid20186543.denovo.052, whole genome shotgun sequence.
ACCESSION   DAVBOD010000052 DAVBOD010000000
VERSION     DAVBOD010000052.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012484
            Sequence Read Archive: ERR059358
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 13168)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13168)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979948.1
            Genome Coverage       :: 595x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:03:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,266
            CDSs (total)                      :: 2,219
            Genes (coding)                    :: 2,091
            CDSs (with protein)               :: 2,091
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 71 of 128
            Pseudo Genes (incomplete)         :: 50 of 128
            Pseudo Genes (internal stop)      :: 33 of 128
            Pseudo Genes (multiple problems)  :: 22 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13168
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012484-rid20186543.denovo.052"
                     /strain="NIG 640-05"
                     /db_xref="taxon:1313"
     gene            268..882
                     /locus_tag="VQ862_001683"
     CDS             268..882
                     /locus_tag="VQ862_001683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001141643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC family ABC transporter permease"
                     /protein_id="HET3115991.1"
                     /translation="MPTALGYVSIGLACGTIGAPYVTPVEMGLMSLFVYAGSAQFAML
                     ALIVVQAPVAAIAMTVFLINLRLFLLSLHASTYFRHTSLWYNIGMSSILTDETYGVLM
                     GELAHTDKVNPMWMHGNNLNSYVAWFVGTVVGTALGGLLPNPEIFALILSSVVTGKVG
                     SLPQIKWLDFLAVFPTAWVAFRYRNLVGTVLFGVVLIAILRLVF"
     gene            986..1816
                     /locus_tag="VQ862_001684"
     CDS             986..1816
                     /locus_tag="VQ862_001684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HET3115992.1"
                     /translation="MKKIVKYSSLAALGLVAAGVLAACSGGAKKEGEAASKKEIIVAT
                     NGSPRPFIYEENGELTGYEIEVVRAIFKDSDKYDVKFEKTEWSGVFAGLDADRYNMAV
                     NNLSYTKERAEKYLYAAPIAQNPNVLVVKKDDSSIKSLDDIGGKSTEVVQATTSAKQL
                     EAYNAEHTDNPTILNYTKADFQQIMVRLSDGQFDYKIFDKIGVETVIKNQGLDNLKVI
                     ELPSDQQPYVYPLLAQGQDELKSFVDKRIKELYKDGTLEKLSKQFFGDTYLPAEADIK
                     "
     gene            1970..2824
                     /locus_tag="VQ862_001685"
     CDS             1970..2824
                     /locus_tag="VQ862_001685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000694494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HET3115993.1"
                     /translation="MKIKKWLGLAALATVAGLALAACGNSEKKADNATTIKIATVNRS
                     GSEEKRWDKIQELVKKDGITLEFTEFTDYSQPNKATADGEVDLNAFQHYNFLNNWNKE
                     NGKDLVAIGDTYISPIRLYSGLNGSANKYTKVEDIPANGEIAVPNDATNESRALYLLQ
                     SAGLIKLDVSGTALATVANIKENPKNLKITELDASQTARSLSSVDAAVVNNTFVTEAK
                     LDYKKALFKEQADENSKQWYNIIVAKKDWETSPKADAIKKVIAAYHTDDVKKVIEESS
                     DGLDQPVW"
     gene            2924..4297
                     /locus_tag="VQ862_001686"
     CDS             2924..4297
                     /locus_tag="VQ862_001686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20/M25/M40 family metallo-hydrolase"
                     /protein_id="HET3115994.1"
                     /translation="MFFPSEQEQIEKFEKDHVAQHYFEVLRTLISKKSVFAQQVGLKE
                     VANYLGEIFKRVGAEVEIDESYTAPFVMAHFKSSRPDAKTLIFYNHYDTVPADGDQVW
                     TEDPFTLSVRNGFMYGRGVDDDKGHITARLSALRKYMQHHDDLPVNISFIMEGAEESA
                     STDLDKYLEKHADKLCGADLLVWEQGTKNALEQLEISGGNKGIVTFDAKVKSADVDIH
                     SSYGGVVESAPWYLLQALQSLRAADGRILVEGLYEEVQEPNEREMALLETYGQRNPEE
                     VSRIYGLELPLLQEERMAFLKRFFFEPALNIEGIQSGYQGQGVKTILPAEASAKLEVR
                     LVPGLEPHDVLEKIRKQLDKNGFDKVELYYTLGEMSYRSDMSAPAILNVIELAKKFYP
                     QGVSVLPTTAGTGPMHTVFDALEVPMVAFGLGNANSRDHGGDENVRIADYYTHIELVE
                     ELIRSYE"
     gene            4290..5351
                     /locus_tag="VQ862_001687"
     CDS             4290..5351
                     /locus_tag="VQ862_001687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000085652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter ATP-binding protein"
                     /protein_id="HET3115995.1"
                     /translation="MSRDIIKLDQIDVTFHQKKRTITAVKDVTIHIQEGDIYGIVGYS
                     GAGKSTLVRVINLLQKPSAGKITIDDDVIFDGKVTLTAEQLRRKRQDIGMIFQHFNLM
                     SQKTAEENVAFALKHSGLSKEEKKAKVAKLLDLVGLADRAENYPSQLSGGQKQRVAIA
                     RALANDPKILISDESTSALDPKTTKQILALLQDLNQKLGLTVVLITHEMQIVKDIANR
                     VAVMQDGHLIEEGSVLEIFSNPKQPLTQDFISTATGIDEAMVKIEKQEIVEHLSENSL
                     LVQLKYAGASTDEPLLNELYKHYQVMANILYGNIEILDGTPVGELVVVLSGEKAALAG
                     AQEAIRQAGVQLKVLKGVQ"
     gene            5353..6045
                     /locus_tag="VQ862_001688"
     CDS             5353..6045
                     /locus_tag="VQ862_001688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET3115996.1"
                     /translation="MESLIQTYLPNVYKMGWAGQAGWGTAIYLTLYMTVLSFIIGGFL
                     GLVAGLFLVLTAPGGVLENKVVFWILDKITSIFRAVPFIILLAILSPLSHLIVKTSIG
                     PNAALVPLSFAVFAFFARQVQVVLAELDGGVIEAAQASGATFWDIVGVYLSEGLPDLI
                     RVTTVTLISLVGETAMAGAVGAGGIGNVAIAYGFNRYNHDVTILATIIIILIIFAIQF
                     LGDFLTKKLSHK"
     gene            complement(6075..6644)
                     /locus_tag="VQ862_001689"
     CDS             complement(6075..6644)
                     /locus_tag="VQ862_001689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000748387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MptD family putative ECF transporter S
                     component"
                     /protein_id="HET3115997.1"
                     /translation="MKKSILTTLLFAVLYFLCMGIGVLLGNLFDQTGNMFYAPAFTAL
                     VGGSVYMILVAKVPRFGAITTIGLVIAFFFLGTKHGAGSFLPGIICGLLADEVAHLGK
                     YKDKTKNFLSFIIFAFSTTGPILLMWIAPKAYMATLLARGKSQEYIDRIMVAPNPGTV
                     LLFIASIVIGALVGALIGQALSKKFAQKI"
     gene            6779..7393
                     /locus_tag="VQ862_001690"
     CDS             6779..7393
                     /locus_tag="VQ862_001690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000532354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HET3115998.1"
                     /translation="MGRFLDFVFNRFFLGMIATAFFWLLTLAGGIILGLAPASATLMS
                     LYAEHGYSFREYSLKEAWSLYKQNFVSSNLIFYSFLGVGLVLTYGLYLLVQLPHQTIV
                     HLIATLLNVLVVALIFLAYTVSLKLQVYFALSYRNSLKLSLIGIFMSLAAVAKVLLGT
                     VLLVAIGYYMPALLFFVGIGMWHFFISDMLEPVYEIIHEKLATK"
     gene            7395..9041
                     /locus_tag="VQ862_001691"
     CDS             7395..9041
                     /locus_tag="VQ862_001691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013670288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HET3115999.1"
                     /translation="MKQFWLHTLLRTYSSVMIIIIASFAILLSYADWDSREKEAQRVA
                     QRVTARTVSEIEYYHRESTQIAQALVENQARIEGIYKYFSLSMPDYFYWQLERKASPY
                     ISVSLYENVDDLYVRNDFVTGVAIAFQDYKEVYVSTKDKRSGEKIRAEDFKPAGNSFA
                     IPVSDPVSDQDLGVIYISLDPAVLYHAIDNTRGNTPMAVTVTSPFDTEIFHIGETVDK
                     ESENWLVGLTSHGYQVQVAVPKNFVLQGTVTSSALIVGLSLLFIVILYLTLRQTFANY
                     QKQVVDLVESIQVIAQGEEGRRIDISEKDQELLLIAETTNDMLDRLEKNIHDIYQLEL
                     SQKDANMRALQAQINPHFMYNTLEFLRMYAVMQSQDELADIIYEFSSLLRNNISDERE
                     TLLKQELEFCRKYSYLCMVRYPKSIAYGFKIDPELENMKIPKFTLQPLVENYFAHGVD
                     HRRTDNVISIKALKQDGFVEILVVDNGRGMSAEKLANIREKLSQRNFEHQASYSDQRQ
                     SIGIVNVHERFVLYFGDRYAITIESAEQAGVQYRITIQDE"
     gene            9053..10339
                     /locus_tag="VQ862_001692"
     CDS             9053..10339
                     /locus_tag="VQ862_001692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000278884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET3116000.1"
                     /translation="MYKVLLVDDEYMVTEGLKRLIPFDKWDMEVVATASHADEALEYV
                     QENPVDVIISDVNMPDKTGLDMIREMKEILPDAAYILLSGYQEFDYVKRAMNLSVVDY
                     LVKPVDKVELGNLLEKIAGQLGERGKKSQTLSQELDEAGFVSYLGDKENWWIGLSKEK
                     QGSFTIPYYVLGQAWQIFISDQPLDGLVVTPFEAPYQEHFERWKLNAEKTLFYGSVNL
                     QQSESLFAYYEPIYRVIIQGNLNQIVEELNLLEKVVLENTPRIPITKQLFIQFVMDVF
                     HLFEHLKADDMTDIVKTIHAIQSFDELVSYIKETLISFFGQYRMNENVVSVLEVIGRD
                     YQKELSLKDISKALFINPVYLGQLIKRETDSTFAELLNKQRIKAAQQLLLSTSDSIED
                     ICYAVGYSNLGYFYKVFRKLCGKSPKAYRKQVETIL"
     gene            10391..10924
                     /locus_tag="VQ862_001693"
     CDS             10391..10924
                     /locus_tag="VQ862_001693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET3116001.1"
                     /translation="MKKKPIYLWVLLILSALISVPSLFGIVSPLPSKEALRVAQKQVA
                     GVNAQQLEDQLNYTYRVAEASHSIFNVALIVLSTILVVVAIVFLVRKNLQYANYTYVG
                     YVLLAIIGSIYGYVGLQDAVQLVQDESMRLTVSIGSKAVSIFYIVINVLFLALVFYKM
                     WRQQKALAEEEETEELA"
     gene            11002..11472
                     /gene="nrdI"
                     /locus_tag="VQ862_001694"
     CDS             11002..11472
                     /gene="nrdI"
                     /locus_tag="VQ862_001694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000849618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HET3116002.1"
                     /translation="MKTISLVYISLSGNTESFVTRLKDYLLSQYKGIEVQKIHIKDLV
                     KEGKNFYEMDHLYVAFLPTYLEGGNGVDNGDVEILTTPVGDFIAYGNNASKCFGVVGS
                     GNRNFNNQYCLTAKQYSQRFGFPVLADFEMRGMLEDIKHVAAIIADLYELEKEN"
     gene            complement(11765..13027)
                     /locus_tag="VQ862_001695"
     CDS             complement(11765..13027)
                     /locus_tag="VQ862_001695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000075801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="divalent metal cation transporter"
                     /protein_id="HET3116003.1"
                     /translation="MSQAISLNQSTWASKLKAMGPGILMATAAVGGSHIVSSTQAGGS
                     YGWSLLLLVILANVFKYPFFRFGAEYTADTGKTLVEGYAEKGKLYLWIFFILNVFSAM
                     VNTAGVAILCSAIIASAFPMIGLSITQWSLILVAIIWAMLLFGGYKLLDGMVKWIMSA
                     LTIATVLAVIIAAVKHPEYSSDFVEKTPWQMAALPFIVSLLGWMPAPIEISAINSLWS
                     AEKRKTVNFNTEDALFDFNTGYIGTAILAVFFVALGALIQYPTGQAVEAASAKYISQF
                     VGMYASVLGEWSRYLITFIAFLCIFGTVITVIDGYSRVNQESLRLLISQKEDNRKSLN
                     IWMTITAIIGIVIIKFFAGQVSTMLRFAMIGSFLTTPFFALLNYALVTRENKNLPSWL
                     KHLAIAGLIFLFGFAIFFIYALAIGKAG"
BASE COUNT         3899 a         2451 c         3007 g         3811 t
ORIGIN      
        1 ttcaatctgc tatataatag tccatgctat ggctggattc ttttcagtct acttatactc
       61 ttcgaaactc tcttcaaacc acgtcagctt caccttgccg tagtacggtt actgacttcg
      121 tcagttctat ccacaacctc aaaacggtgt tttgagcaac ctgcggctag tttcctagtt
      181 tgctctttga ttttcattga gtattattaa gacaatatga ggagaaagat gaaagaaaaa
      241 ggattttagg agggggcgca ggcagccatg ccaacggctc ttggctatgt cagtatcggc
      301 ctggcctgtg ggactatcgg tgcgccctat gtgacacctg ttgagatggg cttgatgagt
      361 ctctttgttt atgctgggag tgcccagttt gccatgttgg cactgattgt ggttcaagct
      421 cctgtggcag ctattgctat gacggttttt ctaatcaact tgcgtctctt tttgttgagt
      481 ttacacgcat cgacttattt ccgtcatacc agtctttggt acaatatcgg tatgtctagt
      541 atcttgacag atgagaccta tggcgttttg atgggtgaat tggcccatac agacaaggta
      601 aatcctatgt ggatgcacgg aaacaatctt aacagctatg tggcttggtt tgtggggaca
      661 gtagtcggaa cggctctggg tggcctgcta ccaaatccag aaatctttgc cttgattctt
      721 tcaagcgtag tgacaggtaa ggttgggagc cttcctcaaa ttaaatggct agacttctta
      781 gccgtctttc caacagcttg ggtagccttt cgctaccgca atctagtcgg aacagttctc
      841 tttggagtgg tcttgattgc catcttgcgt ttggtctttt aaattaccca taaaaaaaac
      901 ttatcacaga gatagatatc atataatggc gtaaatgctc tttttctgtt aagattataa
      961 ggtattctat tttggaggaa atgacatgaa aaaaatcgtt aaatactcat ctcttgctgc
     1021 cctaggactt gttgctgcag gtgtgcttgc ggcttgctca gggggtgcta agaaagaagg
     1081 agaagcagct agcaagaaag aaatcatcgt tgcaaccaat ggatcaccaa ggccatttat
     1141 ctatgaagaa aatggcgaat tgactggtta cgagattgaa gtcgttcgcg ctatctttaa
     1201 agattctgac aaatatgatg tcaagtttga aaagacagaa tggtcaggtg tctttgctgg
     1261 tcttgacgct gaccgttaca atatggctgt caacaatctt agctacacta aagaacgtgc
     1321 ggagaaatac ctctatgccg caccaattgc ccaaaatcct aatgtccttg tcgtgaagaa
     1381 agatgactct agtatcaagt ctctcgatga tatcggtgga aaatcgacgg aagtcgttca
     1441 agccactaca tcagctaagc agttagaagc atacaatgct gaacacacgg acaacccaac
     1501 tatccttaac tatactaagg cagacttcca acaaatcatg gtacgtttga gcgatggaca
     1561 atttgactat aagatttttg ataaaatcgg tgttgaaaca gtgatcaaga accaaggttt
     1621 ggacaacttg aaagttatcg aacttccaag cgaccaacaa ccgtacgttt acccacttct
     1681 tgctcaaggt caagatgagt tgaaatcatt tgtagacaaa cgcatcaaag aactttataa
     1741 agatggaact cttgaaaaat tgtctaaaca attcttcgga gacacttatc taccggcaga
     1801 agctgatatt aaataatttc ttgaaatcat ccattctgag taaggtgggt ggtttctcag
     1861 tttttaggga tatagtttta aactatatat ctgactatct aataacaatt tgtgaaatca
     1921 aacaaattgt gagatactag tacggtatta tttttaagga gaaagaatca tgaaaatcaa
     1981 aaaatggctt ggtctagcag cccttgctac agtcgcaggt ttggctcttg cagcttgcgg
     2041 aaactcagaa aagaaagcag acaatgcaac aactatcaaa atcgcaactg ttaaccgtag
     2101 cggttctgaa gaaaaacgtt gggacaaaat ccaagaattg gttaaaaaag acggaattac
     2161 cttggaattt acagagttca cagactattc acaaccaaac aaagcaactg ctgatggcga
     2221 agtagatttg aacgctttcc aacactataa cttcttgaat aactggaaca aagaaaacgg
     2281 aaaagacctt gtagcgattg gagatactta catctctcca atccgccttt actcaggttt
     2341 gaatggaagt gccaacaagt acactaaagt agaagacatc ccagcaaacg gagaaatcgc
     2401 tgtaccgaat gacgctacaa acgaaagccg tgcgctttac ttgcttcaat cagctggctt
     2461 gattaaattg gatgtttctg gaactgctct tgcaacagtt gccaacatca aagaaaatcc
     2521 aaagaacttg aaaatcactg aattggacgc tagccaaaca gctcgttcat tgtcatcagt
     2581 tgacgctgcc gttgtaaaca ataccttcgt tacagaagca aaattggact acaagaaagc
     2641 acttttcaaa gaacaagctg atgaaaactc aaaacaatgg tacaacatca ttgttgcgaa
     2701 aaaagattgg gaaacatcac ctaaggctga tgctatcaag aaagtaatcg cagcttacca
     2761 cacagatgac gtgaaaaaag ttatcgaaga atcatcagat ggtttggatc aaccagtttg
     2821 gtaataagaa acagggaggt gggagagaaa attccacctc ttgcttttgt atagagtata
     2881 gattgtaaag aagactattc gttcatagaa aggtagagag aatatgtttt ttcctagcga
     2941 acaagaacag attgaaaaat ttgaaaagga tcatgtagcc cagcattatt ttgaggtttt
     3001 gcgtaccttg atttctaaga aatcagtctt tgcccagcag gttggactca aggaagtcgc
     3061 aaactatctg ggtgagattt tcaagcgtgt tggagctgaa gtggagattg atgagagcta
     3121 tacagcgccc tttgtcatgg cacatttcaa gagttcgcgt ccagatgcca agaccttgat
     3181 tttctataac cactatgaca ctgtgccagc ggatggggat caggtctgga cagaggatcc
     3241 ttttacgctt tcggtccgca atggcttcat gtatgggcgt ggggttgatg acgacaaggg
     3301 tcatatcaca gctcgcttga gtgctttgag aaaatatatg cagcaccatg atgatttacc
     3361 tgtcaatatc agctttatca tggagggagc ggaggaatcg gcttcaacag acctagataa
     3421 gtatttggaa aagcatgcag acaaactctg tggggcggat ttgttggtct gggaacaagg
     3481 gaccaaaaat gccttggaac agctggaaat ttctggtggc aataagggaa ttgtgacctt
     3541 tgatgccaag gtaaaaagcg ctgatgtgga tatccactcg agttatggtg gtgttgtgga
     3601 atcagctcct tggtatctcc tccaagcctt acagtctctt cgtgctgcgg atggccgtat
     3661 cttggttgaa ggcttgtacg aagaagtaca agagcccaat gaacgagaaa tggccttgct
     3721 agaaacttat ggtcaacgaa acccagagga agttagtcgg atttatggat tggagttgcc
     3781 tctcttacag gaggagcgga tggcctttct aaaacgtttc tttttcgagc cagcgcttaa
     3841 tatcgaagga atccagtctg gttatcaagg tcagggtgtt aagactattt tacctgcaga
     3901 agccagtgca aagctagagg ttcgtctggt tccgggccta gaaccgcatg atgttctgga
     3961 aaaaattcgg aaacaactag acaaaaatgg ctttgataag gtagaattat actatacctt
     4021 gggagagatg agctatcgaa gcgatatgag cgcaccagcc attctcaatg tgatcgagtt
     4081 ggccaagaaa ttctatccac agggtgtttc agtcttgccg acgacagcgg ggacaggacc
     4141 tatgcatacg gtctttgatg ccctagaggt accaatggtt gcattcggtc taggaaatgc
     4201 caatagccga gaccacggtg gagatgaaaa tgtgcgaatc gctgattatt acacccatat
     4261 cgaattagta gaggagctga ttagaagcta tgagtagaga tattatcaag ttagatcaga
     4321 tcgatgtgac ttttcaccaa aagaagagaa ccattacagc ggttaaggat gtgaccattc
     4381 acatccaaga aggggatatc tacggaatcg ttggatattc tggagcagga aaatcaaccc
     4441 ttgtacgggt gattaacctc ttgcaaaaac catctgcagg gaaaattacc attgacgacg
     4501 atgtgatttt tgatggtaag gtcaccttga cggcagagca gttgcgtcgt aaacgtcaag
     4561 atatcgggat gattttccag cattttaacc tgatgagcca aaagacagca gaggagaatg
     4621 tagcctttgc ccttaaacac tctggactca gcaaggaaga aaagaaggct aaagtagcta
     4681 agttgttgga cttggttggt ttggcagatc gtgctgaaaa ctacccttca caattatctg
     4741 gagggcaaaa acagcgtgtg gcaattgcgc gtgccttggc caatgatcca aaaatcttga
     4801 tttcagacga gtcaacttct gcccttgacc ctaagacaac caagcagatt ttggccttgt
     4861 tgcaagattt gaaccaaaaa ttaggcttga ctgttgtctt gattacgcat gaaatgcaga
     4921 ttgtcaaaga cattgccaac cgtgttgcag ttatgcagga tgggcatttg attgaagagg
     4981 gtagtgtgct tgaaatcttc tcaaacccta aacaaccttt gactcaagac tttatctcaa
     5041 cagctacagg tattgacgaa gccatggtca aaatcgagaa gcaagaaatc gtggaacact
     5101 tgtctgaaaa cagtctcttg gtgcaactca agtacgctgg agcttcaaca gacgagccac
     5161 ttttgaatga attgtacaag cattaccaag taatggctaa tattctctat gggaatatcg
     5221 aaattctcga tggtactcct gttggagaat tggtggtggt tttgtcaggt gaaaaagcag
     5281 cgttggcagg tgcccaagaa gccattcgtc aagcaggtgt acaactaaaa gtattgaagg
     5341 gagtacagta agatggaatc attgattcaa acctatttac caaatgtcta taagatgggt
     5401 tgggctggtc aggcaggctg gggaacggct atctacttaa ctctttatat gacagttctt
     5461 tccttcatta tcggaggctt cttggggcta gtggcaggtc tctttctcgt cttgacagcg
     5521 ccaggtggtg tcttggagaa taaagtcgta ttctggattt tagacaaaat tacctcaatt
     5581 tttcgtgcgg ttccctttat catcctcttg gcaatcttgt caccactttc tcacttgatt
     5641 gttaaaacaa gtatcgggcc aaatgcagcc cttgtcccac tttcttttgc agtctttgcc
     5701 ttctttgccc gtcaggtgca ggttgtcttg gctgaattgg atggcggtgt cattgaggcg
     5761 gctcaagcga gcggagcgac tttctgggac atcgtgggtg tttacctatc agaaggtctt
     5821 ccagatttga tccgtgtgac gactgtgacc ttgatttccc ttgttgggga aacagctatg
     5881 gccggtgcgg ttggagctgg tggtatcggt aacgtagcca tcgcttatgg atttaaccgc
     5941 tacaatcacg atgtgaccat cttggcaacc attattatca ttttgattat ctttgcaatc
     6001 caattcttgg gagatttctt gactaagaaa ttgagccata aataaaaaag agccgcgtgg
     6061 ctctttttaa ctgatcagat tttctgtgca aattttttac tcaaggcttg tccaatcaaa
     6121 gcacccacta gggctccgat gacaatactt gcgataaata gaaggacagt tccagggttt
     6181 ggagcgacca tgatacggtc gatatattct tgggattttc ctcttgccag aagagtagcc
     6241 atataggctt tgggcgcaat ccacataagc aagattggtc ctgttgtact aaaggcgaaa
     6301 ataatgaaag aaaggaagtt ctttgttttg tccttgtatt ttcctaaatg agctacttca
     6361 tctgctagga ggccacagat aattccagga aggaaggaac cagcaccgtg tttagttccc
     6421 aagaaaaaga aggcaatgac aaggccgata gtggtaatgg ctccaaagcg cggaactttt
     6481 gcgactagga tcatatagac gctaccgccg acaagggcag taaaggcagg cgcataaaac
     6541 atgtttccag tttggtcaaa gagattgccc aaaaggacac caatccccat gcagaggaag
     6601 taaagaactg caaaaagcag tgtagttaag atagatttct tcatgaattg tctcctgata
     6661 attttttcac aattctcatt ttaccatggt ttggtgggat tgtaaatgga tactagaagt
     6721 ttttgaaaac gcttgaaata tgatataatg gtttcatagt tatttttagg ggaatatcat
     6781 gggtagattt ttagactttg tctttaatcg tttcttttta gggatgattg cgacagcctt
     6841 cttttggcta ttaactttag caggagggat tatccttggt ctagcgccgg ctagtgccac
     6901 cttgatgagc ttatatgcag aacatggtta tagctttcgg gaatacagtt tgaaggaggc
     6961 ttggtctctt tacaagcaaa attttgtctc aagcaacctg attttctata gctttttagg
     7021 tgtgggtcta gttttgacct atggtttgta tctcttggtg caattgcctc atcagaccat
     7081 tgttcatttg attgcgaccc ttttgaatgt cttagtagtt gccctgatct ttttggctta
     7141 tacagtatct ttaaaattac aagtttattt tgccttgtcc tatcgaaata gtctcaaatt
     7201 atccttgatt ggcatcttta tgagtctagc agctgtggcc aaggttctcc ttgggactgt
     7261 gctacttgta gcaattggtt actatatgcc tgccctgcta ttttttgtag gaattgggat
     7321 gtggcatttc tttatcagtg atatgttgga acctgtctat gaaatcatcc atgaaaaatt
     7381 ggcgacaaaa tagaatgaag cagttttggc tacatacgct tctaagaacc tatagttcag
     7441 tgatgatcat tatcattgcg agttttgcaa tcttactctc ttacgctgac tgggattcac
     7501 gtgaaaagga agcccagaga gtagcccagc gtgtaactgc tagaacagtg agtgaaattg
     7561 aatattacca tagagagtca acccagatag ctcaggcttt agttgaaaat caagctcgta
     7621 ttgagggaat ctataaatac tttagcctta gcatgccaga ctatttttac tggcaattag
     7681 agcggaaagc ttcgccttat atatcagtct ctctgtatga aaatgttgat gacctctatg
     7741 ttcgaaatga ttttgtaact ggagtggcca ttgcttttca agattacaag gaagtctatg
     7801 tttctactaa agacaaacgt agtggagaaa aaatcagggc tgaggatttc aaaccagcag
     7861 gaaatagttt tgccattccg gtgtcagatc cagtgtcaga tcaagattta ggagtgattt
     7921 acatctcctt ggatcctgct gttttatacc atgccattga taatactaga ggtaatactc
     7981 cgatggcagt aacagtgacc tcaccttttg atacggagat ttttcatatt ggtgagacag
     8041 ttgataagga gagtgaaaat tggctagttg gcttaacttc tcatggatat caggttcagg
     8101 tggcagttcc taaaaacttt gttttacaag gaacagtgac tagctctgct ttgattgtgg
     8161 gtttgagcct tctctttatt gtcattcttt atctgacttt gaggcagact tttgctaatt
     8221 accaaaagca ggtagtggat ttagtagaat ccattcaagt cattgctcaa ggcgaagagg
     8281 gtcgtcggat tgacatttcc gagaaagatc aggaattact cctaatcgcg gagacgacca
     8341 atgatatgtt ggatcgattg gaaaagaata tccatgatat ttaccagtta gagcttagtc
     8401 aaaaagatgc taatatgcga gccttgcagg cgcaaatcaa tcctcatttt atgtataata
     8461 cgctggagtt cttgcgcatg tatgcagtta tgcagagtca agatgagttg gcagatatca
     8521 tttatgaatt cagtagtctc ttgcgtaaca atatttccga cgaaagagag accctcctca
     8581 aacaggaatt agaattttgc cgtaaataca gctatctctg catggttcgc tatcccaagt
     8641 ccattgccta tggtttcaag atagatccag agttagagaa tatgaagatt cctaagttca
     8701 ccttgcaacc gctggtagaa aattatttcg cgcatggtgt tgaccacagg cggacagata
     8761 atgtgattag catcaaggct cttaaacagg atggttttgt ggaaattttg gtggtcgata
     8821 atggtagagg aatgtcggct gaaaagttgg caaatatccg agaaaaatta agtcagagaa
     8881 attttgaaca ccaagccagc tacagtgatc aaaggcagtc tatcgggatt gtcaatgtac
     8941 acgagcgttt tgtgctctat tttggagacc gctatgccat tactatagag tctgcagagc
     9001 aagccggtgt tcagtatcgt attacaattc aagatgagta gaaagggaga aaatgtataa
     9061 agtattatta gtagatgatg agtacatggt gacagaaggt ctgaagcgtt tgattccctt
     9121 tgataagtgg gatatggagg tcgtcgcaac agccagtcat gccgatgaag ctctagaata
     9181 tgttcaggaa aatcctgtcg atgtcatcat ttccgatgtc aatatgccag acaaaacagg
     9241 gcttgatatg attcgggaga tgaaagagat cttaccagat gctgcctata tcctgctctc
     9301 aggttatcag gagtttgatt atgtaaaaag agcaatgaac cttagtgtgg tggactattt
     9361 ggtcaaacct gttgataagg tagagctggg aaatctgctg gagaagattg caggtcagct
     9421 cggcgagaga gggaagaaaa gtcagactct tagtcaagaa ttagacgagg ctggatttgt
     9481 tagttattta ggggataagg agaattggtg gataggtcta tccaaggaaa aacaaggttc
     9541 cttcaccatt ccctactatg tcttgggtca agcctggcag attttcattt ctgaccaacc
     9601 cctagatggt ttagtcgtta caccttttga agctccttat caagaacatt ttgaacgctg
     9661 gaagctgaat gctgagaaaa ccctctttta cggttctgta aatctgcagc agtctgagag
     9721 tctctttgcc tattacgaac cgatttatag ggttatcatt cagggaaatc tcaatcaaat
     9781 cgtagaagag ttaaatctct tggagaaggt agttcttgaa aatacgccgc gaattccgat
     9841 tactaaacag ctttttatcc agtttgtcat ggatgtcttc catttatttg aacatctcaa
     9901 agctgatgat atgacggaca ttgtcaaaac cattcatgct attcaatcct tcgatgaatt
     9961 ggtttcttat atcaaggaaa ctctgatcag ctttttcggt caataccgta tgaatgaaaa
    10021 tgtggtcagt gtgctggaag tcattggtcg tgattaccaa aaagagcttt ccctcaagga
    10081 tatcagtaag gccctcttta tcaatcctgt ctatctaggg cagttgatta agcgtgaaac
    10141 cgattcgacc tttgcagagt tactaaacaa acaacgtatt aaggctgccc agcagctctt
    10201 gctttcaacc agtgacagta tcgaagatat ttgttatgct gttggttaca gtaaccttgg
    10261 atatttctat aaagttttcc gaaaattgtg cggaaaatcg ccaaaagcct accgaaaaca
    10321 ggtagaaact atactataag atttgtattc ctttacaaaa tgtgctataa tattatcagg
    10381 aggttctatc atgaaaaaga aaccaattta tctatgggtc ttgctaatct tgtctgccct
    10441 tatttcagtt ccgtctctgt ttggaattgt gagtcccttg cctagtaaag aagcccttcg
    10501 tgttgctcag aaacaagttg caggggtcaa tgctcagcaa ttagaagacc agcttaatta
    10561 tacctataga gtagcagaag catctcattc tatttttaat gttgctttga ttgtgctatc
    10621 tactatttta gtggtcgtag cgattgtctt ccttgttcgt aaaaatttgc aatatgcaaa
    10681 ctatacttac gttggctatg ttttgttagc tattattggt tcgatttatg gctatgttgg
    10741 tttacaagac gctgtgcagt tggttcaaga tgagagcatg cgtttgacag tgagtattgg
    10801 ttcaaaagct gttagcattt tctatatcgt catcaatgtt ctcttcctag cccttgtctt
    10861 ctataagatg tggcgacaac agaaagcctt ggcagaagaa gaggaaacag aagagcttgc
    10921 ctaagtattg acaaaaaaga actatcaaga tacaatcttg gtagttattt tttgattata
    10981 gataaaatca tggaggtaca tatgaagaca atttctttag tttatattag tttgagtggc
    11041 aacactgaaa gttttgtgac gcgcttgaaa gactatctct tgtcccagta caaagggatt
    11101 gaggttcaaa agattcatat caaggatttg gtcaaggaag gcaaaaattt ctatgaaatg
    11161 gaccatctct atgtcgcttt tttgccgacc tatctcgaag gtgggaatgg cgtggataac
    11221 ggagatgttg agattttgac aacaccggtg ggagatttta ttgcctatgg taacaatgct
    11281 agtaagtgtt ttggtgtggt tgggtcagga aatcgtaact ttaataacca atactgccta
    11341 acagccaagc aatacagtca acgctttggc ttccctgtat tggctgactt tgaaatgcga
    11401 ggcatgctgg aagatatcaa acatgtcgca gctattatcg cagatttgta tgagttggaa
    11461 aaggagaatt aatactcaat gaaaatcaaa gagcaaacta ggaagctagt cgcaggttgc
    11521 tcaaagcaca gctttgaggt tgcagataga gctgacgtgg tttgaagaga ttctcgaata
    11581 gtataaagtt cttataagag gtggttgaag ttgttcaact gttttttgag tataaacagt
    11641 ctttaagaac gtaaaaaagc ataagttcag gtcttcaaaa ccttgttctt atgcttttta
    11701 tcatagaaat atttgctgaa ttttctcttg aaatgaaacc ttatcttcat ctcgcgcttg
    11761 tcccttaccc tgcttttccg attgcgagtg cgtagataaa gaagatggcg aagccaaaga
    11821 ggaaaatcaa tcccgcaatg gcaaggtgtt tgagccaaga aggaagattt ttgttttcac
    11881 gcgttaccaa ggcgtaattc aaaagagcaa agaaaggtgt tgtcaggaaa gatccaatca
    11941 tggcaaagcg gagcatggtt gaaacctgac cagcgaagaa cttgataatg acgataccga
    12001 tgatagcagt gatggtcatc cagatgttca aagatttacg attgtcctct ttttgactga
    12061 ttagcagtcg gagagattcc tgattaacgc gagaatagcc atcgataaca gttataactg
    12121 ttccaaagat acagaggaag gcaataaagg taatcaagta acgggaccat tcgccaagaa
    12181 cagaggcata catgcccacg aattgagaga tgtatttggc tgaagcagct tcaaccgcct
    12241 gccctgtagg atactgaatc agtgctccca gtgccacaaa gaagacggct aggatagctg
    12301 ttccaatata accagtgtta aagtcaaaca gagcgtcttc tgtgttaaag ttgacggtct
    12361 ttctcttttc agctgaccaa agtgaattga tagctgaaat ttcaatagga gccggcatcc
    12421 atcctaggag ggagacgatg aagggcagag ctgccatttg ccaaggtgtc ttctcgacaa
    12481 aatcagaact gtattctgga tgcttgaccg ctgctatgat aactgccaga acagtcgcaa
    12541 tggttaaggc agacataatc catttgacca tgccgtctaa aagtttgtag cctccaaaga
    12601 gtagcatagc ccaaatgatt gcaacgagaa tgagggacca ctgagtaatg ctaagtccaa
    12661 tcattgggaa ggcactggcg atgatagctg agcacagaat ggcaacacca gccgtgttga
    12721 ccatagccga aaagacattg aggataaaga aaatccagag atagagtttt cctttttcgg
    12781 cataaccttc aaccaaagtc tttccagtat cagctgtgta ttcagcacca aaacggaaaa
    12841 atggatattt aaagacattg gctaagatga ctaagagaag tagagaccaa ccgtaagaac
    12901 cgccagcttg agttgaggat acaatgtggg aacctccaac agcggcagtt gccattagga
    12961 ttccaggtcc cattgctttt agcttgcttg cccaggttga ttgatttaag gaaatagctt
    13021 gcgacatgat aaatactcct ttttgaattt tcagaataat ctgtatatgt aatctatatt
    13081 ctacaaaaaa ttttggaaaa atgcaagaat attttgaaaa aagatagaaa atttacaaag
    13141 aaaatctgaa ataactgtta tgatatag
//
LOCUS       DAVBOD010000053        13159 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 640-05
            SAMEA1012484-rid20186543.denovo.053, whole genome shotgun sequence.
ACCESSION   DAVBOD010000053 DAVBOD010000000
VERSION     DAVBOD010000053.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012484
            Sequence Read Archive: ERR059358
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 13159)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13159)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979948.1
            Genome Coverage       :: 595x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:03:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,266
            CDSs (total)                      :: 2,219
            Genes (coding)                    :: 2,091
            CDSs (with protein)               :: 2,091
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 71 of 128
            Pseudo Genes (incomplete)         :: 50 of 128
            Pseudo Genes (internal stop)      :: 33 of 128
            Pseudo Genes (multiple problems)  :: 22 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13159
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012484-rid20186543.denovo.053"
                     /strain="NIG 640-05"
                     /db_xref="taxon:1313"
     gene            <1..367
                     /locus_tag="VQ862_001696"
     CDS             <1..367
                     /locus_tag="VQ862_001696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HET3116004.1"
                     /translation="PNLEQVQTMLEQTFTEKHYENTILHSDQGWQYQHDSYHQFLESK
                     GIQASMSRKGNSPDNGMMESFFGILKSEMFYGYEKSFQSRKQLEQAIVDYIDYYNNKR
                     IKVKLKGLSLVQYRTKSFG"
     gene            complement(442..972)
                     /locus_tag="VQ862_001697"
     CDS             complement(442..972)
                     /locus_tag="VQ862_001697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000883388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein kinase family protein"
                     /protein_id="HET3116005.1"
                     /translation="MLDEKRKNYVEDKRQNFPSLPSWKMDLFSEEEKRIYFQTTCEVS
                     SKDSAINKYKIEKIIKRSNKGNVYRAIRKSDGQKVIIKQSRPFVNYDAEGEWTALDDI
                     KNEAYMLKKLADKSYTTNLTDEFYIVDDYFLVQEQVDGLNFEEFIRETEHSLNIREKT
                     LDNIVNIVSDIHKLGI"
     gene            complement(966..1434)
                     /locus_tag="VQ862_001698"
                     /pseudo
     CDS             complement(966..1434)
                     /locus_tag="VQ862_001698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847907.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            1984..2661
                     /locus_tag="VQ862_001699"
     CDS             1984..2661
                     /locus_tag="VQ862_001699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000624068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenine-N(1))-methyltransferase"
                     /protein_id="HET3116006.1"
                     /translation="MISKRLELVASFVPQGAILLDVGSDHAYLPIELVERGKIESAIA
                     GEVVEGPYQSAVKNVEAHGLEEKIQVRLANGLAAFEEEDRVSVITIAGMGGRLIARIL
                     EEGLDKLANVERLILQPNNREDDLRIWLQDHGFQIVAESILEEAGKFYEILVVEAGQM
                     KLSASDVRFGPFLSKEVSPVFVQKWQKEAEKLEFALGQIPEKNLEERQVLVDKIQAIK
                     EVLHVSK"
     gene            2648..3445
                     /locus_tag="VQ862_001700"
     CDS             2648..3445
                     /locus_tag="VQ862_001700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000881127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nif3-like dinuclear metal center hexameric
                     protein"
                     /protein_id="HET3116007.1"
                     /translation="MLASEVIQAYEAFCPQEFSMEGDSRGLQIGTLDKGIQRVMVALD
                     IREETVAEAIEKGVDLIIVKHAPIFRPIKDLLASRPQNQIYIDLIKHDIAVYVSHTNI
                     DIVENGLNDWFCQMLGIEETTYLQETGPERGIGRIGNIQPQTFWELAQQVKQVFDLDS
                     LRMVHYQENDLQKPISRVAICGGSGQSFYKDALAKGADVYITGDIYYHTAQDMLSDGL
                     LALDPGHYIEVLFVEKIAALLTQWKEKKGWELEILPSQASTNPFRHI"
     gene            3462..4565
                     /locus_tag="VQ862_001701"
     CDS             3462..4565
                     /locus_tag="VQ862_001701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-binding oxidoreductase"
                     /protein_id="HET3116008.1"
                     /translation="MKKVAIIGAGIVGATAAYYLSRESDLEVTVFDHEQGQATKAAAG
                     IISPWFSKRRNKAWYKMARLGADFYVDLLADLEKSGQKIDFYQRSGVFLLKKDESKLE
                     ELYQLALQRREESPLIGQLAILDQASANELFPGLQGFDRLLYASGGARVDGQLLVTRL
                     LEASHVKLVKEKVTLTLLSSGYQIGEEVFDQVILATGAWLGDMLEPLGYEVDVRPQKG
                     QLRDYQLAQDMEDYPVVMPEGEWDLIPFAGGKLSLGATHENDMGFDLTVDEPLLQQME
                     EAALPHYPVLARATSRAERVGIRAYTSDFSPFFGQVPELAGVYVASGLGSSGLTTGPI
                     IGYHLAQLIQDKELTLDPLNYPIENYVKRVKSE"
     gene            4866..5885
                     /gene="galE"
                     /locus_tag="VQ862_001702"
     CDS             4866..5885
                     /gene="galE"
                     /locus_tag="VQ862_001702"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HET3116009.1"
                     /translation="MQEKILVTGGAGFIGTHTVIELIQAGHQVVVVDNLVNSNRKSLE
                     VVERITGVEIPFYEADIRDTVTLRDIFKQEEPTGVIHFAGLKAVGESTRIPLAYYDNN
                     IAGTVSLLKAMEENNCKNIIFSSSATVYGDPHTVPILEDFPLSVTNPYGRTKLMLEEI
                     LTDIYKADSEWNVVLLRYFNPIGAHESGDLGENPNGIPNNLLPYVTQVAVGKLEQVQV
                     FGDDYDTEDGTGVRDYIHVVDLAKGHVAALKKIQKGSGLNVYNLGTGKGYSVLEIIQN
                     MEKAVGRPIPYRIVERRPGDIAACYSDPAKAKAELGWEAELDITQMCEDAWRWQSKHP
                     NGFED"
     gene            5887..6840
                     /locus_tag="VQ862_001703"
     CDS             5887..6840
                     /locus_tag="VQ862_001703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HET3116010.1"
                     /translation="MMISIIVPCLNEEEVLPLFYQALEALLPDLETEIEYVFVDDGSS
                     DGTLELLKAYREQNPAVHYISFSRNFGKEAALYAGLQYATGDLVVVMDADLQDPPSML
                     FEMKNVLDKNVDLDCVGTRRTSREGEPFFRSFCAVLFYRLMQKISPVALPSGVRDFRM
                     MRRSVVDAILSLTESNRFSKGLFAWVGFKTHYLDYPNVERQAGKTSWSFRQLFFYSIE
                     GIVNFSDFPLTIAFVAGLLSCFLSLLMTFFVVVRTLILGNPTSGWTSLMAVILFLGGI
                     QLLTIGILGKYISKIYLETKKRPLYLIKEKSDLPDFTEKIK"
     gene            complement(6902..7108)
                     /locus_tag="VQ862_001704"
     CDS             complement(6902..7108)
                     /locus_tag="VQ862_001704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001843159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin"
                     /protein_id="HET3116011.1"
                     /translation="MKITLIPERCIACGLCQTYSDLFDYHDNGIVRFYDDPDQLEKEI
                     SPSQDVLEAVKNCPTRALIGNQEA"
     gene            7160..7636
                     /locus_tag="VQ862_001705"
     CDS             7160..7636
                     /locus_tag="VQ862_001705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM domain-containing protein"
                     /protein_id="HET3116012.1"
                     /translation="MAKEPWQEDIYDQEESRAGRRHRNHGGADRMANRILTILASIFF
                     VIVVVMVIVLIYLSSGGSNRTAALKDFHDSDASVVQISSSSSSQPEQSSEPESTSSSS
                     EEAANPEGTIKVLAGEGEAAIAARAGISIAQLEALNPGHMATGSWFANPGDVIKIK"
     gene            7645..8316
                     /locus_tag="VQ862_001706"
     CDS             7645..8316
                     /locus_tag="VQ862_001706"
                     /EC_number="2.7.4.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000849376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(d)CMP kinase"
                     /protein_id="HET3116013.1"
                     /translation="MKTIQIAIDGPASSGKSTVAKIIAKDFGFTYLDTGAMYRAATYM
                     ALKNQLGVEEVEALLALLDQHPISFGRSETGDQLVFVGDVDITHPIRENEVTNHVSAI
                     AAIPEVREKLVSLQQEIAQQGGIVMDGRDIGTVVLPQAELKIFLVASVDERAERRYKE
                     NIAKGIETDLETLKKEIAARDYKDSHRETSPLKQAEDAVYLDTTGLNIQEVVEKIKAE
                     AEKRM"
     gene            8447..8785
                     /locus_tag="VQ862_001707"
     CDS             8447..8785
                     /locus_tag="VQ862_001707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002920966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkylphosphonate utilization protein"
                     /protein_id="HET3116014.1"
                     /translation="MNNLPNCPKCNSEYVYEDGALLVCPECAHEWNPAEVTEVEEGLV
                     AIDANGNKLTDGDTVTLIKDLKVKGAPKDLKQGTRVKNIRIVEGDHNIDCKIDGFGAM
                     KLKSEFVRKI"
     gene            8788..9417
                     /locus_tag="VQ862_001708"
     CDS             8788..9417
                     /locus_tag="VQ862_001708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000033944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Pr6Pr family membrane protein"
                     /protein_id="HET3116015.1"
                     /translation="MSKHYKLVFYSRIFLFLAAFTGVYLEITRHGGFGMLLYYTVLSN
                     LLVTIFTLYLLKVMSRVGENWQRPSLLRLKGGVTMSIMITCVIYHFLLAPIATNFYTL
                     ENFLCHYIVPIWFLADTLFFDKQGQYKIWDPAVWTILPFLYMMFALFNGLVLKLNIPN
                     AKDNPFPYFFLNVNKGWNVVFKWCLIIFVAYMVAGFIFYFIKQIKRKSS"
     gene            9657..10808
                     /locus_tag="VQ862_001709"
     CDS             9657..10808
                     /locus_tag="VQ862_001709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000808687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HET3116016.1"
                     /translation="MKQFLERASILALSLVLITSFSISSALPAMFDYYQGYSKEQIEL
                     LVSLPSFGIMMMLLLNGFLEKIFPERLQISLGLLILSLSGTAPFWYQAYPFVFGTRLL
                     FGLGLGMINAKAISIISERYQGKRRIQMLGLRASAEVVGASLITLAVGQLLAFGWTAI
                     FLAYSAGFLVLPLYLLFVPYGKSKKEVKKRAKEASRLTREMKGLIFTLAIEAAVVVCT
                     NTAITIRIPSLMVERGLGDAQLSSFVLSIMQLIGIVAGVSFSFLISIFKEKLLLWSGI
                     TFGLGQIVIALSSSLWVVVAGSVLAGFAYSVVLTTVFQLVSERIPAKLLNQATSFAVL
                     GCSFGAFTTPFVLGAIGLLTHNGMLVFSILGGWLIVISIFVMYLLQKRA"
     gene            11126..11875
                     /gene="truA"
                     /locus_tag="VQ862_001710"
     CDS             11126..11875
                     /gene="truA"
                     /locus_tag="VQ862_001710"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HET3116017.1"
                     /translation="MTRYKATISYDGYAFAGFQRQSHARSVQEEIEKTLTRLNKGQAI
                     TVHGAGRTDSGVHALGQVIHFDLPYQIDEEKLRFALDTQSPEDIDVISIELVADDFHC
                     RYAKHSKTYEFIVDRGRPKNPMRRHYATHFPYPLDVERMQIAIKKLEGTHDFTGFTAS
                     GTSVEDKVRTITEASLIVDETGQFLTFTFSGNGFLYKQIRNMVGTLLKIGNNRMPVEQ
                     IALILEKKDRQLAGPTAAPNGLYLKEIRYEE"
     gene            11865..12638
                     /locus_tag="VQ862_001711"
     CDS             11865..12638
                     /locus_tag="VQ862_001711"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HET3116018.1"
                     /translation="MKNNRILALSGNDIFSGGGLSADLATYTLNGLHGFVAVTCLTAL
                     TEKGFEVFPTDDTIFQHELDSLRDVEFGGIKIGLLPTVSVAEKALDFIKQRPGVPVVL
                     DPVLVCKETHDVAVSELCQELIRFFPYVSVITPNLPEAELLSGQEIKTLEDMKTAAQK
                     LHDLGAPAVIIKGGNRLSQDKAVDVFYDGQTFTILENPVIQGQNAGAGCTFASSIASH
                     LVKGDKLLPAVESSKVFVYRAIAQADQYGVRQYEANKNN"
     gene            12616..13077
                     /locus_tag="VQ862_001712"
     CDS             12616..13077
                     /locus_tag="VQ862_001712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HET3116019.1"
                     /translation="MKQTKTTKIALVSLLTALSVVLGYFLKIPTPTGILTLLDAGVFF
                     AAFYFGSREGAVVGGLASFLLDLLSGYPQWMFFSLVNHGLQGFFAGFKGKSQWLGLIL
                     ATIAMVGGYALGSTLMNGWAAALPEILPNFMQNMAGMIVGFILSQSIKKIK"
BASE COUNT         3763 a         2466 c         2903 g         4027 t
ORIGIN      
        1 acccaactta gaacaagtac aaacaatgtt ggaacagaca ttcacagaga agcactacga
       61 gaatacgatt ctccatagtg accaaggctg gcaataccaa cacgattctt atcatcagtt
      121 cctagagagt aagggaattc aagcatccat gtcacgtaag ggcaacagcc cagacaacgg
      181 tatgatggag tccttctttg ggattctgaa atcggaaatg ttttacggtt atgagaagtc
      241 gtttcagtcg cgtaagcaat tggaacaagc tattgtagac tatattgatt actacaacaa
      301 taaacgaatt aaggtaaaac taaaaggact tagccttgtg caatacagaa ctaaatcctt
      361 cggataaatt aattgtctaa ctttttgggg ggcagtacat ttttggtata tataaaattt
      421 gtaggagcta tatctacaat tttatattcc cagtttatgg atgtcgctta ctatgttcac
      481 aatgttatcc agtgtttttt ctctaatatt taaggagtgt tctgtttctc gaataaattc
      541 ttcaaagttt aacccgtcaa cttgttcctg aacaagaaaa taatcatcca cgatataaaa
      601 ttcatcagtt aaattagtag tataactttt atcggctaat ttttttagca tgtaagcctc
      661 attttttata tcatcaagtg ctgtccattc tccttcggca tcataattca caaaaggtct
      721 tgactgcttg atgattactt tttgcccgtc cgattttcta attgcccgat aaacattccc
      781 tttatttgat ctcttaataa ttttttctat tttgtattta tttattgcag agtccttact
      841 tgaaacttca catgtggttt gaaaataaat ccttttttct tcttctgaaa ataaatccat
      901 tttccagcta ggaagactag ggaaattttg tctcttatct tctacatagt tcttcctttt
      961 ttcatctagc aataaataga tgactttttt atttttttca tcataagctt gtttttttaa
     1021 aaaagcccca tatctataat gaactggaga atgcattcca cattgatagt cagatagtat
     1081 ttttggagcc ttaaattctg acagtctatt cgtaagatta caaatcatac tcttagcttc
     1141 agattctgac ttaggatata gagttataaa tttgttagca gtagggctca tttccctagg
     1201 ggaattaatt ctttttaatt cctctaaatt tttaacaact ttaaagctac aattatttag
     1261 ttgggatagt ttatacacaa tcttaaaaat atttacagcg tcttttattt gggagcttat
     1321 gtgtattttc cacccttgtg caggcacctt atctgataaa taatagtaat tccaaatatc
     1381 accctgttgg aaatttttat cacattttaa acattctttc tctaataaat ccataacaaa
     1441 ctcctaatta ttaaaatagg ctagagacac agcactagcc tattccgtaa gtaaagctac
     1501 ttattttata taaaatataa ctagcgacct gtaattaaac aagtaaaaga acaatactta
     1561 gggagacctg tgacaatgat atcttcctct ggaagtagtt ctaattcaaa caatgtttgt
     1621 tccatgactg tatcctcctg ttatgataaa ttccagaaag catagagcaa attcgtggtt
     1681 cgtctgacta aatttcttat ctgaacacca ccttcaaata caaattttag tcaaactttt
     1741 attttttcta actttctaat tatattctac catgtgtttt tatatgtcaa gaattttctg
     1801 aataaactgt ttatttttta tttttttgac atttttgcaa attgtttaaa atctttcaat
     1861 tggattcact tattacttta ggacattgaa gcttctttcg ccagaggtgc ttatattact
     1921 gggaagttga agattgaaat gtggtataat aagaggtaat agagttttgg aaagagagag
     1981 aagatgattt caaagagatt agagttggta gcttcctttg tgccgcaggg agccatttta
     2041 ctagatgtgg ggagtgacca tgcttatttg cctatagagt tagtcgaaag aggaaaaatc
     2101 gaaagtgcca ttgcaggtga agttgtggag ggaccttatc agtctgctgt caaaaatgtt
     2161 gaggcccacg gcttggaaga aaaaatccaa gtccgtttag ccaatggttt ggcagctttt
     2221 gaagaggaag accgagtgtc tgtcattacc atcgcaggga tgggcggccg tttgattgct
     2281 aggattttag aagaaggctt ggacaagtta gctaacgtag agcgtttgat tctccagccc
     2341 aataatcgtg aagacgactt gcgtatctgg ctacaggatc atggattcca gattgtagca
     2401 gaaagcatct tagaagaagc tggaaagttt tatgagattt tggtggtgga agcaggacaa
     2461 atgaagctat cagccagtga tgttcgcttt ggtcccttct tgtccaaaga agtcagtcca
     2521 gtatttgtcc aaaaatggca aaaagaagct gagaagctag agttcgccct cggacaaatc
     2581 ccagaaaaaa atctggaaga acgtcaagtt ctagtagata agattcaagc tatcaaggag
     2641 gtgctccatg ttagcaagtg aagtgatcca agcttatgaa gccttttgcc ctcaggaatt
     2701 ttctatggag ggagacagcc gtggtctgca aattggcact ttagacaagg gtatccaaag
     2761 ggtcatggtt gccctcgata ttcgtgaaga gacagtggca gaggccattg aaaagggtgt
     2821 ggacttgatt atcgtcaagc acgcgcctat ctttcgtcct atcaaggact tgcttgccag
     2881 ccgtccgcaa aatcagattt acatcgacct gattaagcat gacatcgcag tttatgtcag
     2941 ccataccaat attgatatcg ttgaaaatgg gctcaatgac tggttttgtc agatgctagg
     3001 aatcgaggag acgacttatc tgcaggaaac aggtccagaa cgtggaattg gacgtattgg
     3061 gaatattcag cctcagacat tttgggaatt ggcccaacag gtcaagcaag tctttgacct
     3121 agatagcctt cgaatggtgc attatcaaga gaatgatttg cagaagccta tttcaagagt
     3181 agcaatttgt ggtggaagcg ggcagtcttt ctataaggat gctttggcaa agggggcaga
     3241 tgtctatatc actggtgata tctactacca tactgctcag gatatgctgt ctgatggctt
     3301 gttagcattg gatccaggtc actatatcga agtgcttttt gtggaaaaaa tcgcagcact
     3361 ccttactcaa tggaaagaga aaaaaggctg ggaactagag attttaccta gtcaagcatc
     3421 gaccaatcct ttccgtcata tctagttaga aagtgaagac aatgaaaaaa gttgccatta
     3481 ttggagcagg aattgtggga gcaacagctg cctactacct ctcgagagaa agtgacctag
     3541 aggtgaccgt ttttgaccat gagcaaggtc aagccaccaa ggccgcagca ggaattatca
     3601 gtccttggtt ttccaaacgc cgtaataaag cctggtacaa gatggcgcgc ttgggggctg
     3661 acttttatgt ggatttatta gctgatttag agaaatcagg acaaaaaatc gacttttacc
     3721 agcgttcggg agtctttctc ttgaaaaagg atgaatccaa gttggaagaa ctttatcaac
     3781 tggccctcca gcgcagagaa gaatctccct tgatagggca attagccatt ctggaccaag
     3841 cttcagctaa tgaattattc cctggtttgc agggatttga ccgcctgctc tatgcttctg
     3901 gtggagcgag agtagatggc caactcttgg taactcgtct gctagaagcc agtcatgtca
     3961 agctggtcaa agaaaaagtg actctgacac tcttatcatc aggctaccag attggcgaag
     4021 aggtgtttga tcaggttatt ttggcaacgg gagcttggtt gggggacatg ttagagcctt
     4081 taggttatga agtggatgtc cgtcctcaaa aaggacaact acgagattat cagcttgccc
     4141 aagacatgga agattaccct gttgtcatgc cagaagggga gtgggatttg attccctttg
     4201 caggtgggaa attatccttg ggcgctaccc atgaaaatga catgggattt gatttgacgg
     4261 tagatgaacc cttgctccaa caaatggagg aggcggcctt gcctcattac ccagttttag
     4321 ctagagcgac ttcaagggct gagcgtgtgg gaatccgtgc ctataccagt gatttctctc
     4381 ccttctttgg gcaggtgcca gaattggcag gtgtctatgt agccagtgga ctaggttcat
     4441 caggcctcac aactggtcct atcattggtt accatctagc ccaactgatc caagacaagg
     4501 agttgacctt ggaccctcta aattacccaa ttgaaaacta tgtcaaacga gtaaaaagcg
     4561 aataatactc aatgaaaatc aaagaacaaa ctaggaaact agccgcgggt tactcaaagc
     4621 actgctttga ggttgtgtat agaactgacg aagtcagctc aaaacactgt tttgaggttg
     4681 tgtatagaac tgacgaagtc agtaaccata cccatggcaa ggcgacgttg acgtggtttg
     4741 aattggattt tcgaagagta taagcatttt actgaaattt tatcaggtag tttaggatgg
     4801 caaatgacat tccctgtcaa aaatggtaaa ataagaaaaa ataatctgag aatcgaggaa
     4861 aaaagatgca agaaaagatt ttggtaactg gtggtgccgg ttttattgga acccacactg
     4921 ttattgaatt gatccaagca ggccatcaag ttgttgtggt ggataatctt gtcaatagca
     4981 atcgtaagag tttagaagtt gttgaaagaa tcacaggagt tgagattcct ttctatgagg
     5041 cagatattcg tgacacagtt accctcagag atattttcaa gcaggaagaa ccgactggtg
     5101 tcattcactt tgctggtttg aaggctgttg gcgaatcaac acgtatccct cttgcctact
     5161 atgacaacaa tatcgctgga actgtcagcc ttttgaaagc catggaagaa aacaactgta
     5221 aaaacatcat cttcagttct tctgcgacag tttacgggga tccgcacaca gtgcccatct
     5281 tggaagattt cccactttca gtgaccaacc catacggtcg taccaagctc atgctagagg
     5341 aaattttgac cgatatttac aaagcagact cagaatggaa tgttgtcttg cttcgttact
     5401 ttaacccaat cggagcccat gagagtggtg atttgggaga aaatccaaac ggtattccaa
     5461 acaatctctt gccatatgtg actcaagtag ccgttggaaa attagagcaa gtgcaagtgt
     5521 ttggagacga ttacgatacg gaagatggaa caggtgttcg tgactatatc cacgttgtcg
     5581 atttggctaa gggtcacgtt gcagctttga aaaaaatcca aaaaggttca ggactaaacg
     5641 tttataacct tggaactggt aaaggttact cagttcttga aattatccaa aacatggaaa
     5701 aagcggtggg acgtcctatt ccttaccgca tcgtagaacg tcgcccaggt gatatcgctg
     5761 cctgctactc agacccagca aaagctaaag cagaactcgg ttgggaagca gaactcgaca
     5821 tcacccaaat gtgtgaagac gcatggcgtt ggcaaagcaa gcatccaaat ggatttgaag
     5881 actaagatga tgatttcaat catcgtccct tgtttaaacg aagaggaagt acttcctctt
     5941 ttttatcagg ctctggaagc tttacttcca gatttggaaa cagaaatcga gtatgtcttt
     6001 gtcgatgatg gatcaagtga tgggaccttg gaactcttaa aggcctatcg ggagcaaaat
     6061 ccggcagtcc attatatttc tttctctcga aattttggca aagaagcagc cctttatgca
     6121 ggcttgcaat atgcgacagg agatttggtg gtggtgatgg atgcagacct ccaagatcct
     6181 cctagtatgt tgtttgagat gaaaaatgta ctagacaaaa atgtagactt ggactgcgtt
     6241 gggacacgga gaactagtcg ggagggagaa cccttctttc gcagtttctg tgctgttctc
     6301 ttttatcgcc tcatgcaaaa aatcagccca gtagctctgc cgtcgggtgt ccgtgatttt
     6361 cgtatgatga gaaggtctgt ggtcgatgcc attttaagct tgactgagtc caatcgtttt
     6421 tctaagggac tctttgcctg ggtcggcttt aaaacccact atctggacta tccaaatgtc
     6481 gaaaggcagg ctggcaagac cagttggagt tttaggcaac tcttttttta ctccattgaa
     6541 gggattgtta atttttcaga tttccctttg actatagcct ttgtagctgg tctcctatct
     6601 tgttttcttt ctctgctgat gacctttttt gttgtggttc ggaccctcat tttgggcaat
     6661 ccgacatctg gttggacctc tctgatggct gttattctct ttcttggagg cattcaactc
     6721 ttgaccattg ggattctcgg taagtatatc agtaagattt atttagagac taaaaaaaga
     6781 ccactttatc ttatcaaaga aaaaagtgac cttcctgatt ttacagaaaa aataaagtga
     6841 aaagactata attttacatg gaaatgtgct aaactagagg gagtggatta tcgccattga
     6901 tttaggcttc ctggtttcca atcagggcgc gagttgggca atttttaaca gcctctaaga
     6961 catcctgact aggagaaatt tctttttcca gttggtcagg gtcatcgtaa aaacgcacga
     7021 ttccattatc gtggtaatca aataaatcag aataagtttg gcaaagtcca caggcgatac
     7081 atcgttcagg tataagtgtg attttcatgt tcatatttat attgtaataa gaaaagtaaa
     7141 aaaaaacaag gagtaaggta tggcaaaaga accgtggcaa gaagatattt atgatcaaga
     7201 agaatcaaga gcagggcgtc ggcatcgaaa ccacggaggg gctgatagga tggctaatcg
     7261 tattttgacg atcctagcta gtattttctt tgtaattgtg gtggtgatgg tcatcgttct
     7321 catctatcta tcatcggggg ggagtaatcg cacagcagcc ttaaaagact ttcatgattc
     7381 tgatgcaagt gtagtacaaa tctcatcttc aagcagttct cagcctgagc agagttcaga
     7441 gccagaatct acttctagta gttcagaaga agctgctaat cctgaaggaa cgattaaagt
     7501 tctcgcagga gaaggggaag cagctattgc cgctcgtgca ggaatctcca ttgctcagtt
     7561 agaggccttg aatcctgggc acatggctac aggatcttgg tttgctaatc caggtgatgt
     7621 tataaaaata aaataggagc cgatatgaaa acaattcaaa ttgctattga tggtcctgct
     7681 tccagcggta agagtacggt cgcaaagatt attgctaagg attttggatt cacctacctt
     7741 gatacaggag ctatgtatcg tgcagcgacc tatatggctc ttaagaacca attaggagtt
     7801 gaagaagtcg aagcccttct agccttgttg gaccagcatc caatcagctt tggacgttca
     7861 gaaactggag accagcttgt ttttgtagga gatgtggata ttacccatcc tatccgtgaa
     7921 aatgaagtga ccaatcatgt ttctgctatt gcagcaattc ctgaagtgcg tgagaaactg
     7981 gtttctctcc aacaagaaat tgcccagcaa ggcgggattg tcatggatgg tcgcgatatt
     8041 ggaactgttg tattgccaca agcagaattg aaaattttcc tagtagcttc tgttgatgag
     8101 agagcagagc gtcgttacaa ggaaaatatt gccaagggaa ttgaaacaga ccttgaaacc
     8161 ctaaaaaagg aaattgctgc gcgtgactac aaggatagtc atcgtgagac ttctcctctc
     8221 aaacaagcag aggatgctgt ctaccttgat acaactggtt tgaacattca agaagtagtt
     8281 gaaaaaatca aagcagaagc tgaaaaaaga atgtaaatgt agaaaagccg atagattgat
     8341 atcggttttt ttctaaattt gtcaaaatgc tgattttagg gtataatagt tgctgttcga
     8401 gaaattttga ttttcaaaga atagtgaatg atgataagga gaaaccatga acaatttacc
     8461 aaattgtccc aaatgtaact cagagtatgt ctacgaagac ggtgccctac tggtttgccc
     8521 agagtgtgct catgagtgga atcctgctga agttacagaa gtagaagaag gtcttgtcgc
     8581 tatcgatgcc aacggaaata aattgactga tggtgataca gtaactctca tcaaggactt
     8641 gaaagtaaaa ggtgcgccaa aagatttgaa acaagggacg cgcgtgaaaa atatccgcat
     8701 cgtagaaggc gaccacaata tcgactgtaa gattgatggt tttggtgcca tgaaacttaa
     8761 atcagagttt gtgaggaaga tttaagcatg tcaaaacact ataaacttgt attttatagc
     8821 cgtatcttct tgtttctagc ggcttttacg ggagtttatc ttgaaattac taggcatggt
     8881 ggttttggga tgcttctcta ttacacggtt ctgtccaacc tcttggtaac tatttttacc
     8941 ctttatcttc taaaggttat gagccgtgta ggtgaaaatt ggcaaaggcc aagtctcttg
     9001 cgcttaaaag gtggggtcac catgagcatc atgattacct gtgtgattta ccatttcctc
     9061 ttggcgccca ttgcgactaa tttctatacc ctagaaaatt tcctttgcca ctatatcgtt
     9121 cccatctggt ttttagcgga taccctcttt tttgacaaac agggtcaata caagatttgg
     9181 gatccagcag tgtggaccat tttacccttt ctgtatatga tgtttgctct ttttaatggc
     9241 ttggttctaa aactcaatat tccaaatgcc aaggataatc ctttccctta cttctttttg
     9301 aatgtgaaca agggttggaa tgttgtgttt aagtggtgtc tgattatctt tgttgcctat
     9361 atggtagcag gatttatttt ctactttatc aagcaaatca agagaaagtc atcctaatac
     9421 tcttcgaaaa tctcttcaaa ccacgtcagt ttccatctgc aacctcaaaa cactgttttg
     9481 aacaacctgc ggctagcttc ctagtttgct ctttgatttt cattgagtat aagatacaag
     9541 ggattcattt tcgaatttaa gaaggagtct acaaaccaat gaggcttctt cttttcttgc
     9601 ttatttgata actatcaaaa aagtagaaga ttaagagaaa tatagaaaga gatttcatga
     9661 aacaattttt agaacgggcc agcattttgg ctctctccct cgttttgatt acctcctttt
     9721 ccatttcgag tgccctacca gccatgtttg actattatca gggttattct aaggaacaaa
     9781 ttgagctctt ggtgagcttg ccttcctttg gaattatgat gatgttactg ctaaatggtt
     9841 tcttagaaaa aatatttcct gagcgcttac agattagttt gggcttgctg attttatcat
     9901 tgagcggtac agctcccttc tggtaccaag cctatccctt tgtctttgga acacggcttc
     9961 tctttggttt gggtcttggg atgatcaatg ccaaggccat ttctattatc agtgaacgct
    10021 accaaggaaa aaggcgaatt cagatgttag ggctacgcgc ttctgcagag gtcgttggag
    10081 cttctctcat taccttggcc gtcggtcagt tgttggcctt tggttggaca gctatctttc
    10141 tagcctatag tgctggattt ttggtgctgc ccctttatct gctctttgtc ccttatggaa
    10201 aatcaaagaa agaagtcaag aaaagagcga aggaagcaag tcgtttaact cgagaaatga
    10261 aaggcttgat ttttacctta gctatcgaag cggcagttgt agtttgtacc aatacagcta
    10321 ttaccatccg tattccaagt ttgatggtgg aaagaggatt gggggatgcc cagttatcta
    10381 gttttgttct tagtatcatg cagttgatcg ggattgtggc tggggtgagt ttttctttct
    10441 tgatttctat ctttaaagag aaactgctcc tctggtctgg tattaccttt ggcttggggc
    10501 aaattgtgat tgccttgtct tcatccttgt gggtggtagt agcaggaagt gttctggctg
    10561 gatttgccta tagtgtagtc ttgacgacgg tctttcaact tgtctctgaa cgaattccag
    10621 ctaaactcct caatcaagca acttcatttg ctgtattagg ctgtagtttc ggagccttta
    10681 cgaccccatt tgttctaggt gcaattggct tactaactca caatgggatg ttggtcttta
    10741 gtatcttagg aggttggttg attgtaatct ctatctttgt catgtaccta cttcagaaga
    10801 gagcttagga ttgattccta agtttttctt ttgatactca atgaaaatca aagagcaaac
    10861 tatagttgat tgagtttgga atagtacgct gtagctgcta aaatatttct agaaattaat
    10921 ttgactttcc taatagagtt attcatatct tatttcaatc tactatagaa agctagccgc
    10981 aggttgctca aaatagtgtt ttgaggttgc agatggaaac tgacgtggtt tgaagagatt
    11041 ttcgaagagt atgagatttt tatacccata caatatttgt tttaggtcct tgtttacaga
    11101 ctaatttctt gataaaatag aggttatgac gagatataaa gcaactattt cctatgatgg
    11161 ttatgccttt gctggctttc agcgccagtc tcatgcgcgt agcgttcagg aagaaattga
    11221 aaaaaccttg accagattaa ataaagggca agccattact gttcacggtg ctggtaggac
    11281 agatagtggg gttcatgccc tgggacaggt cattcatttt gacctgcctt atcagattga
    11341 tgaggagaaa ctccgttttg ccttggatac ccagtctcct gaagatattg atgtgatttc
    11401 gattgagctt gtggcagatg attttcattg ccgttatgcc aagcatagca agacctatga
    11461 gtttattgtg gatagaggac gtcccaaaaa tccgatgcgc cgtcactatg ccacccactt
    11521 tccctaccca ctcgatgtgg aacgaatgca gattgcaatc aaaaagctag agggaaccca
    11581 tgattttacc ggttttacag cctctgggac tagtgtagag gataaggttc gcaccatcac
    11641 agaagctagt ttaatagtcg atgagacagg acaatttttg acctttacct tttccggaaa
    11701 tggtttcttg tataaacaga ttcgcaatat ggtggggact cttctcaaaa tcggtaacaa
    11761 ccgcatgcca gtagagcaga ttgctctcat cttggagaag aaggacaggc aacttgcagg
    11821 tcccactgca gcaccaaatg gtttgtattt aaaggagatt cgttatgaag aataatcgta
    11881 ttttagcact ttctggaaat gatattttta gtggtggtgg actgtcagct gatttggcta
    11941 cctatacctt gaacggcttg catgggtttg tagcagtgac ttgtttgaca gccttgacag
    12001 aaaaaggatt tgaagtcttt ccaactgatg ataccatttt tcaacatgaa ttagatagct
    12061 tgcgtgatgt ggaatttggg ggaattaaga ttggtcttct ccctactgtc agtgtggctg
    12121 agaaggcctt ggactttatc aaacaacgcc caggagtacc tgtggtgttg gatcctgtct
    12181 tggtctgcaa ggaaacgcat gatgtagctg tcagtgagct ctgccaagag ttgattcgct
    12241 ttttccctta tgtcagtgtg attacgccta atctcccaga agcagaatta ttatccggtc
    12301 aggaaattaa aaccttggaa gacatgaaaa ctgcagcgca gaaattgcat gatttaggag
    12361 ctccagcagt cattatcaag ggaggcaatc gtcttagtca ggacaaggct gtggatgtct
    12421 tttatgatgg acagaccttt actatcctag aaaatccagt tatccaaggc caaaatgctg
    12481 gtgcaggttg tacctttgcc tctagcattg ccagtcactt ggttaaaggt gataaacttt
    12541 tgccagcagt agaaagttct aaggttttcg tttatcgtgc tattgcacaa gcagatcagt
    12601 atggagtaag acaatatgaa gcaaacaaaa acaactaaaa tcgcccttgt atccctatta
    12661 accgcccttt ctgtggttct aggttatttc ttaaaaatcc caacacctac aggaattcta
    12721 actcttttag atgctggtgt cttctttgcg gccttttact ttggtagtcg tgaaggagcg
    12781 gtagtcggag gactagcaag tttcttgctt gacctcttat caggctaccc tcagtggatg
    12841 ttttttagct tggtcaacca tggcttgcag ggatttttcg caggatttaa aggaaaaagt
    12901 cagtggttag gccttatttt agcaactatt gccatggtag ggggctacgc cttgggttct
    12961 actttgatga atggctgggc agcagccctc ccagaaattc taccaaattt tatgcaaaat
    13021 atggcaggga tgattgtagg atttattctt agtcaaagta tcaagaagat taagtaatac
    13081 tcttcgaaaa tctcttcaaa ccacgtcggc ttccatctgc aacctcaaaa cactgttttg
    13141 agcagcctgc ggctagctt
//
LOCUS       DAVBOD010000054        13074 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 640-05
            SAMEA1012484-rid20186543.denovo.054, whole genome shotgun sequence.
ACCESSION   DAVBOD010000054 DAVBOD010000000
VERSION     DAVBOD010000054.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012484
            Sequence Read Archive: ERR059358
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 13074)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13074)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979948.1
            Genome Coverage       :: 595x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:03:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,266
            CDSs (total)                      :: 2,219
            Genes (coding)                    :: 2,091
            CDSs (with protein)               :: 2,091
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 71 of 128
            Pseudo Genes (incomplete)         :: 50 of 128
            Pseudo Genes (internal stop)      :: 33 of 128
            Pseudo Genes (multiple problems)  :: 22 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13074
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012484-rid20186543.denovo.054"
                     /strain="NIG 640-05"
                     /db_xref="taxon:1313"
     gene            complement(278..1501)
                     /locus_tag="VQ862_001713"
     CDS             complement(278..1501)
                     /locus_tag="VQ862_001713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000628995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family transcriptional regulator"
                     /protein_id="HET3116020.1"
                     /translation="MITKQSAFLQNRATILEFLYRNPATSRTDIVNETGLTPATTTNI
                     IKELSEQSLIYETGDEFSEFSGSGRRRKTISITDNIPYVVGGIEINVLGIFLSLCDLQ
                     GKTLFETEILNEDYPISEINSTITNMIKTAIEYVPLETKLLGFGLSIPGHYNKDSGSI
                     ITNNPIWESFNLLNVIKRFNFPFIVKNNIDCMAIGQYLFNPHNTPDNFIFLHAGLGIY
                     TSFFTKEKIGASKNPYIGEIGHTIVELNGQYCECGKKGCLQTYISDAWLIKHAQLLFK
                     NSQLTVLKSLVKTEKDIHLDTLLTAYNLGDSALRQQIDKGVNLLATSIANLLLINPAD
                     KIYINSQLLNYQPFTHEVRDKIQDQLHFVPFTRNIEIEILPYNKHRGSIGACALAIVA
                     FFIEHSNVLQDIISP"
     gene            1669..2991
                     /locus_tag="VQ862_001714"
     CDS             1669..2991
                     /locus_tag="VQ862_001714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001059752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HET3116021.1"
                     /translation="MNNILAFLETKVAPFGEKVGNQRHLKAIREGFMMAMPLILVGSL
                     FLILISWPQEDFTNWLNSVGLLSILTTMNQSTVAIISLVACFGIAYRLSEGYGTDGPS
                     AGIIALSSFVLMAPRFSSMVYDKNGEQVKQLFGGAIPFSSLNASSLFMAITIGLVTAE
                     IYRMFIQRGITIKMPSGVPDVVSKSFSALLPGFTTFVLWALVLKGLEAAGVAGGLNGL
                     LGGIVGTPLKLIAGTLPGMILCVIVNSFFWFCGVNGGQVLNAFVDPVWLQFTIENQEA
                     VAAGQTLQHIITLPFKDLFVFIGGGGATIGLAICLFLFSKSRANKTLGKLAIIPSIFN
                     INTAILFTFPTVLNPIMLIPFIATPTINALITYVSMAVGLVPYTTGVILPWTMPPIIG
                     GFLATGASWRGALLQVVLILVSVAIYYPFFKIADKRNLEKEKATVGGK"
     gene            2993..4879
                     /locus_tag="VQ862_001715"
     CDS             2993..4879
                     /locus_tag="VQ862_001715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000236922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4838 domain-containing protein"
                     /protein_id="HET3116022.1"
                     /translation="MVIRVFDQQKNTYSSFALEELSYYMNRVFKTNIELVEEKEADIF
                     VGLVNKEDRKDHVLISLDKGKGRIESNTIVGLLIGIYRMFHEFGVVYTRPGRRHDFVP
                     ELRFEDFLDKQLSIDETASYYHRGVCIEGADSFENILDFIDWLPKIGMNSFFIQFENP
                     YSFLKRWYEHEFNPYLNKEQFSNELVQELSDRLDKELQKRGLIHHRVGHGWTGEVLGY
                     SSKFGWESGLSISEEKKPYVAEINGKRELFNTAPILTSLDFSNPDVADKMVEIIKDYA
                     KKRPDVNYLHVWLSDARNNICECENCRQELVSDQYIRILNQLDRALTSEGLDTKICFL
                     LYHELLWAPQKEKLDNPERFTMMFAPITRTFEMSYADVDFDNSIPTPKPYLRNKIILP
                     NSLEENLSYLFEWQKTFKGDSFVYDYPLGRAHYGDLGYMKISQTIYRDVSYLSNLHLN
                     GYISCQELRAGFPHNFPNYVMGEMLWKKTRSYEELIEEYFSALYGSNWQSVVEYLEKL
                     SSYSSCDYFNAIGSRQNDVLANHYYIAYNLADNFLPIIEENISKLLNSQKDEWKQLSY
                     HREYVVKMAKALYLQATGKTRQAQDEWRNVLNYIRGHELLFQSNLDVYRVIEVAKNYA
                     GFHL"
     gene            5047..5391
                     /locus_tag="VQ862_001716"
     CDS             5047..5391
                     /locus_tag="VQ862_001716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000836781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HET3116023.1"
                     /translation="MKSKEEINMLGFTIVAYAGDARSDLMDALAFARDGYFEQARELV
                     ESANDSIVSAHREQTNLLAEEASGDNFEVSFIMIHGQDTLMTTMLLYDQVKFFIDEYE
                     RIRKIEEHIGLQ"
     gene            5401..6813
                     /gene="lacG"
                     /locus_tag="VQ862_001717"
     CDS             5401..6813
                     /gene="lacG"
                     /locus_tag="VQ862_001717"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000429433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HET3116024.1"
                     /translation="MENLQVKALPKEFLLGAATAAYQVEGATRVDGKGTNMWDVYLQE
                     NSPFLPDPASDFYYRYEEDIALAAEHGLQALRLSISWVRIFPDIDGEPNILAVRYYHR
                     VFQSCLKHNVIPFVSLHHFDSPQKMLETGDWLNRENIDRFIRYARFCFQEFTEVKHWF
                     TINELMSLAAGQYIGGQFPPNHHFQLSEAIQANHNMLLAHALAVREFHQLGIEGKIGC
                     IHALKPGYPIDGQKENILAAKRYDVYNNKFLLDGTFLGYYSEDTLFHLNQILEANNSS
                     FIIEDGDLEIMKRAAALNTMFGMNYYRSEFIREYKGENRQEFNSTGIKGQSSFKLNAL
                     GEFVKKPGIPTTDWDWNIYPQGLFDMLLRIKEEYPQHPVIYLTENGTALKEVKPEGEN
                     DIIDDSKRIRYIEQHLHKVLEARDRGVNIQGYFIWSLQDQFSWANGYNKRYGLFFVDY
                     ETQKRYIKKSALWVKGLKRN"
     gene            6883..8562
                     /locus_tag="VQ862_001718"
     CDS             6883..8562
                     /locus_tag="VQ862_001718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000359733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HET3116025.1"
                     /translation="MDKLVAAIEKQQGKFEKISTNNYMMAIKDGFIATMPLIMFSSFL
                     MIIIMIPKNFGVELPSPAIAWMRKVYMLTMGVLGIIVSGTVAKSLAGNVNRKMPPGKV
                     INDTSAMLAAICGYLVLTVTLVVDEKTGSTSLSTNYLGSQGLITSFVSAFITVNVYRF
                     CIKRDITIHLPKEVPGAISQAFRDIFPFSFVLLISGLLDIVSRFSLDVPFAQVFQQLL
                     TPIFKGAESYPAMMLIWFMCALLWFVGIHGPSIVLPAVTALQLSNMEENAQLLANGQF
                     PYHSLTPNFGNYIAAIGGTGATFVVPFILIFFMRSKQLKSVGKATITPVLFAVNEPLL
                     FGMPVILNPYLFVPFLMTPPVNVFLGKVFIDFFGMNGFYIQLPWAFPGPLGLLIGTNF
                     QLISFVFLSLMLVVDILIYLPFCRAYDRQLLVKEDIASSNDIILEEDTSEIMPCEIDV
                     IKSKELKVLVLCAGSGTSAQLANAINEGAQLAEVRVIANSGAYGAHYDIMGVYDLIIL
                     APQVRSYYREMKVDAERLGIQIVATRGMEYIHLTKSPSKALQFVLEHYQAV"
     gene            complement(8688..10127)
                     /locus_tag="VQ862_001719"
     CDS             complement(8688..10127)
                     /locus_tag="VQ862_001719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HET3116026.1"
                     /translation="MNKSMIRYLLSKLLLIEAVLLLVPVAIAVYYRESSQVFTALFST
                     IGILVLLGGSGSLQKPKNQRIYAKEGVLIVALCWILWSFFGGLPFVFSGQIPSVIDAF
                     FEISSGFTTTGASILNDISVLSRSLLFWRSFTHLIGGMGVLVFALAIMDNAKNSHLEV
                     MKAEVPGPVFGKVVSKLKNTAQILYLLYLALFSLFVIIYYLAGMPLYDSFVIAMGTAG
                     TGGFTVYNDGIAHYGSSLITYLVSIGVLVFGVNFNLYYYLMLRRIKAFFGDEELRAYL
                     VIVLVSTGLISLNTLYLYPGFSKSFEMTFFQVSNIITTTGFGYGDITNWPLFSQFILL
                     FLMAIGGSAGSTAGGLKIIRGLILSKIAKNQILSILSPHRVLTLHVNKTVIDKDTQHK
                     ILKYFVIYAMILLALIFIVSLDSNDFLVVTSAVFSCFNNIGPILGTTSSFSIFSPISK
                     ILLSFAMIAGRLEIYPILLLFMKRTWSKR"
     gene            complement(10131..11480)
                     /gene="trkA"
                     /locus_tag="VQ862_001720"
     CDS             complement(10131..11480)
                     /gene="trkA"
                     /locus_tag="VQ862_001720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Trk system potassium transporter TrkA"
                     /protein_id="HET3116027.1"
                     /translation="MKIILVGGGKVGFALCRSLVAEKHDVLLIEQDEAVLNHIVNRFD
                     IIGILGNGADFAILEQASVQDCDIFIALTEHDEVNMIAAVLAKKMGAKETIVRVRNPE
                     YSNSYFKEKNILGFSLIVNPELLAARAIANIIDFPNALSVERFAGGRVSLMEFVVKST
                     SGLCQMPISDFRKKFGNVIVCAIERDHQIIIPSGDMTVQDKDRIFVTGNRVDMILFHN
                     YFKSRAVKSLLIVGAGRIAYYLLGILKDSRIDTKVIEINPEIASFFSEKFPNLYIVQG
                     DGTAKDILLEESAQHYDAVATLTGVDEENLITSMFLDRVGVQKNITKVNRTSLLEIIN
                     APDFSSIITPKSIAVDTIMHFIRGRVNAQYSDLQAMHHLANGQIETLQFHIKEANKMT
                     AKPLSQLKLKKGVLIAAIIRKGKTIFPTGEDMLEVGDKLLVTTLLPNITKIYDLIAR"
     gene            11668..12516
                     /locus_tag="VQ862_001721"
     CDS             11668..12516
                     /locus_tag="VQ862_001721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-adenosyl-l-methionine hydroxide
                     adenosyltransferase family protein"
                     /protein_id="HET3116028.1"
                     /translation="MNNNLLVLQSDFGLVDGAVSAMIGVALEESPTLKIHHLTHDITP
                     YNIFEGSYRLFQTVDYWPEGTTFVSVVDPGVGSKRKSVVAKTAKNQYIVTPDNGTLSF
                     IKKHVGIVAIREISEVANRRQNTEHSYTFHGRDVYAYTGAKLASGHITFEEVGPELSV
                     EQIVELPVVATIIEDHLVKGAIDILDVRFGSLWTSITREEFYKLEPEFGDRFEVTIYH
                     ADMLVYQNQVVYGKSFADVRIGQPILYINSLYRLGLAINQGSFAKAYNVGVGSSWTIE
                     IKKIEG"
     gene            12531..>13074
                     /locus_tag="VQ862_001722"
     CDS             12531..>13074
                     /locus_tag="VQ862_001722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000403170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF-type riboflavin transporter
                     substrate-binding protein"
                     /protein_id="HET3116029.1"
                     /translation="MEIKFTIKQVVAVGIGAALFVVIGMINIPTPVPNTSIQLQYAVQ
                     ALLSIIFGPIIGLLVGLIGHAIKDSLAGYGLWWTWIIASGLFGLVVGLFRKYVRVING
                     VFDWKDILIFNLIQLLANALVWGVLAPLGDVVIYQEAAEKVFAQGIVAGIANGVSVAI
                     AGTLLLLAYAGTQTRAGSLKK"
BASE COUNT         3998 a         2093 c         2791 g         4192 t
ORIGIN      
        1 gagaattgta aaaacaaaaa tggggatttc atataaagtt tattctagga gtatgtatct
       61 tgaataaaaa ttgttattta agttctgggg gttatgatga atgtttttat aataataaaa
      121 tgcagctaga agaaaagtta ttttaatata aatcactcaa catagagaga aggcggtttc
      181 ctatatggaa gtcgtcttgt tttcatattg tctaaatacg agatatttac tacaggttat
      241 agttgattta aacaggtcta tagatttcta atatatatta aggtgaaata atatcttgta
      301 atacattgct atgctctatg aaaaaagcaa cgatagctaa tgcacaagct cctatacttc
      361 cacgatgttt gttgtaaggt aaaatttcaa tttctatatt acgagtaaag ggaacgaagt
      421 ggagctggtc ttggatttta tccctgactt catgagtgaa aggttgataa ttaagcaatt
      481 gactgttgat atagatttta tcagcaggat tgatgaggag aagatttgca atagaagtgg
      541 ctaataaatt gactccttta tcaatttgtt gacgtaaagc ggagtcgcct aaattataag
      601 ccgttaaaag ggtgtctaaa tgaatgtctt tttcagtctt tacaaggctt tttagtacag
      661 ttagttggga atttttaaat aataattggg cgtgtttgat taaccaagca tccgaaatat
      721 atgtttgtaa acaacctttt tttccgcatt cacaatattg cccattcaat tcgacaatgg
      781 tgtgtccaat ttctccgata taaggatttt tagaggctcc tattttttct tttgtgaaaa
      841 aggaagtgta aatacctaat ccagcgtgta ggaaaataaa gttatcgggg gtattgtgtg
      901 gattaaaaag gtattgtcct atagccatac aatcgatatt attttttaca ataaaaggaa
      961 aattgaatct tttaattaca tttaataaat taaaagattc ccatatgggg ttgtttgtaa
     1021 tgatacttcc ggagtctttg ttataatgtc caggtattga taagccaaat ccaagtaatt
     1081 ttgtttccaa agggacgtac tctatagctg tttttatcat attggtaatg gtggaattga
     1141 tttctgaaat aggataatct tcattcaaaa tttctgtctc gaaaagagtt ttcccttgta
     1201 agtcacatag actgagaaag atacctagga cgtttatttc aatacctcca acaacatacg
     1261 gaatattatc tgtgatagaa atagtttttc tacgtcttcc agatccggaa aactcgctaa
     1321 attcatcacc agtttcgtat atgagggact gttcgcttag ctcttttatg atgttagtcg
     1381 ttgttgctgg agtaagtcct gtttcattaa caatatctgt acgggatgtt gctggatttc
     1441 gatatagaaa ctccagtata gtggctctat tttgtaaaaa ggctgattgt tttgtaatca
     1501 tttgtttcct cctttggttt attttatatt aaacataaga aaaaatcaat taaaattatt
     1561 attctataca aagaaaaaaa tattgtaaaa acaacaaaaa atatattgac aacgctttct
     1621 gttagtggta tatttaattt ataaaaaata aaaaaaggag ttccggtgat gaacaatatt
     1681 ttagcgtttt tagaaacaaa agtcgctccg tttggtgaaa aagttggcaa ccaacggcat
     1741 ttgaaagcta ttcgtgaagg atttatgatg gcaatgcctt tgattttagt cggatcttta
     1801 tttcttattc taatcagttg gcctcaagag gattttacaa attggctgaa tagtgttgga
     1861 ttgctaagta tcttgacaac tatgaatcag tcaacagtag cgattatctc cttggtcgct
     1921 tgtttcggta ttgcctacag gttgtcggaa ggatatggta cagatggtcc gtcggcaggg
     1981 atcatagcct tatccagttt tgtattgatg gcacctcgtt tttcgagtat ggtttatgat
     2041 aaaaatgggg agcaggtcaa gcagttattt ggcggcgcaa taccattttc tagcctgaat
     2101 gcatcttctt tgtttatggc gattactatt ggattggtta cagcagagat ttatcgtatg
     2161 tttatccagc gcggaattac gataaaaatg ccaagtggtg tcccagatgt ggtaagtaaa
     2221 tcattttcag ctcttttacc tggctttact acttttgttt tgtgggctct ggtcttaaaa
     2281 ggtcttgaag cggcaggagt tgcaggaggt ctcaacggac tcctaggtgg aattgttgga
     2341 acaccgctta agttaattgc aggaacgctt ccaggtatga ttctatgtgt tattgtaaac
     2401 tcattctttt ggttctgtgg agttaatggg ggacaagttt taaatgcttt tgtagatcca
     2461 gtttggttac aatttactat agaaaaccaa gaagctgtgg ctgcaggaca aacactccaa
     2521 cacattatta cattaccgtt taaagattta tttgtattta ttggtggcgg tggagcgact
     2581 attggtcttg cgatttgtct cttcctattt agtaagagtc gtgcgaataa aacattaggt
     2641 aagctagcta ttataccgtc tatttttaat atcaatacag ctattctatt tacgtttcca
     2701 acagttttaa atccgattat gctgattccg tttattgcta ctcctacaat caatgccttg
     2761 attacctatg tatcaatggc tgtaggatta gtaccctata caacaggtgt aatccttccg
     2821 tggacaatgc caccgattat aggaggcttc cttgcaacag gggctagttg gcgaggagct
     2881 ctattacaag ttgttttgat tttggtttct gtagcaattt attatccatt cttcaaaatt
     2941 gcagataaac gcaatcttga aaaagaaaaa gctactgttg gagggaaata agatggttat
     3001 cagagtattt gatcaacaga aaaatactta ttctagcttt gccttagagg aattaagtta
     3061 ctatatgaat cgggtcttta agactaacat agagcttgtc gaggagaagg aagcggatat
     3121 ttttgtagga ttagtcaata aagaggacag aaaagaccat gttcttatct cattagacaa
     3181 gggtaaggga agaattgagt ctaatacaat tgtaggttta cttattggaa tttaccgaat
     3241 gtttcatgaa tttggggttg tgtatactag accagggcgc agacatgact ttgttccaga
     3301 gttacgattt gaagattttt tagataaaca gctatctata gatgaaacag ccagttacta
     3361 tcatagggga gtatgtatag agggagcgga ttcatttgaa aatatactag atttcattga
     3421 ttggctacct aagattggga tgaacagttt tttcatccag tttgaaaatc cttactcttt
     3481 tttgaaacgt tggtatgaac atgaatttaa tccatatcta aataaagaac aattttcaaa
     3541 tgaattagta caagaattga gtgataggtt ggataaagaa ttgcaaaaaa gaggtcttat
     3601 tcatcatcgt gttggtcatg gatggacagg tgaagtttta ggttactctt caaaatttgg
     3661 ctgggaatca ggtcttagta tttcagagga gaagaaaccc tatgtcgctg aaataaacgg
     3721 gaaacgagaa ttgtttaata cggctccgat tttaaccagc ctggattttt caaatccaga
     3781 tgtagctgat aagatggtag aaattatcaa ggattatgcc aagaaaagac ctgatgttaa
     3841 ctacttacat gtatggttgt cggatgctcg taataatatt tgtgaatgcg aaaactgtag
     3901 acaagaattg gtttcggatc agtatattcg tattctcaat caattggata gggctttaac
     3961 gagtgaggga ttagatacaa agatttgttt tctgctttac catgagttgc tatgggcgcc
     4021 tcagaaagaa aaattagata atcctgaacg ctttaccatg atgtttgcac cgattacaag
     4081 aacatttgaa atgagttatg cagatgtaga ttttgacaat tccataccta cgcctaaacc
     4141 ttatctgcgt aataaaatta tacttccgaa ttctcttgag gaaaatttat cttatctttt
     4201 tgagtggcaa aaaacattta aaggagatag tttcgtatat gactatcctt tagggcgtgc
     4261 tcattatggc gatttaggct atatgaaaat tagtcaaacc atttacagag atgtatctta
     4321 tctttctaac ctacatttga acggttacat ttcgtgtcaa gaattacgtg ccggattccc
     4381 tcataatttt cctaattatg ttatggggga aatgctctgg aagaagacaa gaagttatga
     4441 agaattgatt gaagaatact tttctgcttt gtatgggtca aattggcagt ctgttgttga
     4501 atatttagaa aaattatcca gttattcctc atgtgattat tttaatgcaa ttggcagtcg
     4561 tcaaaatgat gttttagcga atcattatta tatagcttac aatctagctg ataatttttt
     4621 gccaattatt gaggaaaata tttctaagtt attaaatagt caaaaggatg aatggaaaca
     4681 gctcagttat catcgtgaat atgttgttaa gatggcgaag gctttatatc ttcaagcaac
     4741 cggaaaaaca aggcaagctc aagatgaatg gagaaatgtg ttgaattata tccgtgggca
     4801 cgaactgcta ttccaatcta atttggatgt ttatcgtgta attgaagtag caaaaaatta
     4861 cgctggtttc cacttataaa tcataagtat agaaaatgaa ccaaggtatt cagagaagat
     4921 tgatcctaaa tattatgaaa tttaaggatt tttaagatat ttagggtcga ctttctattt
     4981 atatcgtagc gaagtcattt taataatgat gtgtaaaaga tggatcaaga ttgaggagga
     5041 agaaagatga aatcaaaaga agaaataaat atgcttggtt ttacaattgt cgcttacgca
     5101 ggagatgcaa ggtcagattt gatggatgct ttggcgtttg cgagagatgg atattttgaa
     5161 caggcaagag aattggttga gtctgcaaac gactcaatag tgtctgccca tcgagaacag
     5221 actaatttat tagcggagga ggcatctgga gataattttg aagtgagttt tatcatgatt
     5281 catggtcaag ataccttgat gacaacgatg ctattgtatg atcaggtcaa gttttttatt
     5341 gatgaatatg aacgaattcg aaagattgaa gaacatattg gtttgcaatg aggattagtc
     5401 atggaaaatt tacaggttaa agccttaccg aaggagtttt tattaggagc tgctaccgct
     5461 gcttatcaag tagagggtgc aactagggta gatggcaaag gaacaaatat gtgggatgtt
     5521 tatttgcaag aaaacagtcc gtttttacca gatccggcta gtgattttta ttatcgttac
     5581 gaagaggata tagctttggc ggcagaacat ggtttgcagg ctttgcgttt atctatttct
     5641 tgggttcgta tatttcctga tatagatggg gagcctaata tattagctgt tcgttattac
     5701 catagagtct ttcagtcttg cttaaaacat aatgtgattc cgtttgtttc tttacatcat
     5761 tttgattcgc ctcagaaaat gttagaaaca ggggattggt tgaatagaga gaatattgat
     5821 cgtttcatac gatatgctcg cttttgtttc caagaattta cagaagtcaa gcattggttt
     5881 acaatcaatg aactgatgtc tcttgctgca ggtcaatata taggaggtca gtttcctcca
     5941 aatcatcatt ttcaattatc tgaagcaatt caagcgaatc ataatatgtt gttggcgcat
     6001 gctcttgcag tccgcgaatt tcatcaatta gggattgagg gaaagatagg ttgtattcat
     6061 gctttaaagc caggctatcc tattgatggg caaaaagaaa atattttggc agctaaacgg
     6121 tatgatgttt ataataataa atttctatta gatggaactt ttttgggcta ctacagtgag
     6181 gacacgcttt ttcacttgaa tcaaatattg gaagctaata attctagctt tattattgaa
     6241 gatggtgatt tagaaattat gaagagagct gcagctctta atacgatgtt tgggatgaat
     6301 tattatcgtt cagaatttat tcgtgaatac aaaggtgaaa atagacaaga atttaattca
     6361 acaggaataa aaggacagtc ttcttttaaa ttaaatgctc taggtgaatt tgtaaaaaaa
     6421 cctggtattc cgacaacaga ttgggattgg aatatttatc ctcaagggtt atttgatatg
     6481 ttgcttcgta tcaaagaaga atatcctcaa catccggtca tttatttaac tgaaaatggt
     6541 acagccctta aagaagttaa gccagagggc gagaatgata ttattgatga cagtaagaga
     6601 atccgttata ttgagcaaca tttacacaaa gttttagagg ctcgagatag aggagtcaat
     6661 attcaaggct attttatatg gtctttgcaa gatcaatttt cttgggcgaa tggctacaat
     6721 aagcgatatg gtcttttctt tgttgattat gaaacacaga agagatatat taagaaaagt
     6781 gctctttggg taaaagggct aaaacggaat taaggttagc gatttgactg atgtttaata
     6841 tattttaact atgagcttaa attttttaca ggaggagttt ttatggataa gttagtcgct
     6901 gccattgaaa agcaacaagg gaaatttgaa aaaatttcta ctaataatta tatgatggct
     6961 attaaagatg gatttattgc tactatgcct ttaattatgt tttcaagctt tttgatgatt
     7021 attattatga ttcctaaaaa tttcggagta gagttaccga gtccagctat tgcctggatg
     7081 aggaaagtgt atatgctaac catgggagtt ttgggtatta ttgtttcagg gacagttgca
     7141 aagtcattgg ctggaaatgt taatagaaaa atgcctcctg gaaaggtaat aaatgatact
     7201 tctgcaatgt tggcggccat atgtggctat cttgtattaa ctgtaacgct tgtagttgat
     7261 gagaaaacgg gatctacaag tttgtcgaca aactatttag gatctcaagg attgataact
     7321 tcgtttgtca gtgcctttat tactgtaaat gtttaccgat tctgtattaa gcgagacatt
     7381 actattcatt tacctaagga agttcctggg gctatatcac aagcttttag agatattttt
     7441 cctttttctt ttgttttact tattagtggt ttgttagata ttgtatctcg ttttagttta
     7501 gatgttcctt ttgcccaagt atttcaacaa ctattgactc ctatttttaa gggggcagaa
     7561 tcatatcctg ctatgatgtt gatttggttt atgtgtgctt tgctttggtt tgttggaatt
     7621 catggaccat ctattgtctt acctgctgtt acagctttac aactgagcaa tatggaagag
     7681 aatgctcaac ttcttgcaaa tgggcagttc ccttatcatt ctttaacacc taatttcggg
     7741 aattatatcg ctgctattgg aggaacgggg gctacctttg ttgtaccatt tattttgatt
     7801 ttctttatgc ggtctaaaca attaaaatcg gtaggtaaag ctacaattac tcctgtttta
     7861 tttgcggtaa atgaacctct tctatttggt atgcctgtta ttttgaatcc ctatcttttt
     7921 gtaccttttt tgatgactcc accagtgaat gtatttctag gaaaggtatt tattgatttc
     7981 tttggaatga atggatttta tatccagtta ccttgggcct ttcctggtcc cttgggattg
     8041 ttaattggaa cgaattttca acttatctcc tttgtatttt tatctttgat gttagttgtc
     8101 gacatattga tttatttgcc attctgtaga gcgtatgata gacagttact ggtgaaagaa
     8161 gatattgcaa gctcaaatga tattatttta gaggaggata caagtgaaat aatgccttgt
     8221 gagatagatg taataaaaag taaggagttg aaagtactgg ttctttgtgc agggtctgga
     8281 acaagtgcgc aattagccaa tgcaattaac gagggcgctc aattagcaga agttagagtg
     8341 attgcgaatt caggagcgta cggagctcat tatgatatta tgggtgttta tgatttaatt
     8401 attctggccc cacaagttcg gagttattat agagagatga aggtggatgc agaaagatta
     8461 ggtattcaga tagttgctac cagaggaatg gaatatattc atttaacaaa gagtccaagt
     8521 aaagccttac aatttgtatt ggagcattac caagctgtgt agtaagtttt tccatctttt
     8581 atttgagtaa agattttgct tacagatagg cttggattta aaaacgttcc ccctttttta
     8641 atataagaat ccctctttca caattgtaaa aagagggatt ttgtatttta tctcttagac
     8701 caagttctct tcataaagag aaggaggatt gggtaaatct ccaagcgccc tgcaatcatt
     8761 gcaaaggata ggagaatttt tgagatggga ctaaagattg agaaactaga agtggttcct
     8821 agaataggcc cgatattatt gaaacagcta aagacagcgc tggtcacgac cagaaaatca
     8881 ttgctatcta ggctgacaat aaagataagc gctagcaaaa tcatagcata gatgacaaag
     8941 tacttgagaa tcttatgctg ggtatctttg tcaatcaccg ttttattaac atggagggtc
     9001 aaaacacggt ggggcgatag gattgacaaa atttggtttt tggcaatttt tgaaaggatg
     9061 aggcctcgaa taatcttgag tccacctgca gttgatccag cagagccacc gattgccatg
     9121 aggaaaagga ggataaactg ggagaagagg ggccagttgg taatatctcc atatccaaaa
     9181 ccagttgttg taatgatgtt ggaaacctgg aagaaggtca tttcaaagct ctttgaaaac
     9241 cctgggtaga ggtagagggt gttgaggcta atcaagcctg tagaaaccag tacaatgacc
     9301 aagtaagccc gaagttcttc gtcaccaaag aaggccttga tgcgacggag catgaggtag
     9361 tagtagaggt tgaaatttac cccaaaaacc agaactccga tactgaccag ataggtaatc
     9421 agtgagctgc catagtgggc aattccgtcg ttatagacgg taaagcctcc agttcccgct
     9481 gtccccatag caatgacaaa actatcgtag agaggcatac cagctagata atagatgatg
     9541 acaaagaggg agaagagagc tagataaagg agatagagaa tctgggcagt gttttttagt
     9601 ttggatacaa ccttgccaaa aacaggacct ggaacctcag ccttcatcac ctctaggtgg
     9661 ctatttttgg cattgtccat aatagcaagt gcaaaaacaa gcactcccat ccctccaatc
     9721 aagtgggtaa aacttcgcca gaagaggagg gaacggctga gaaccgaaat gtcgttcaaa
     9781 atacttgctc cagtagttgt aaacccagaa ctaatttcaa aaaaggcatc aataacgcta
     9841 gggatttgcc cagaaaagac aaaggggaga ccaccaaaga aagaccaaag gatccaacag
     9901 agggcaacga tcaagactcc ctccttggca taaatccgtt gattttttgg cttctgtaaa
     9961 ctccctgaac cgcctaacaa tacgagaatc cctatggtcg aaaagagggc tgtaaagact
    10021 tggctcgatt cacggtaata gacagcgata gccacaggaa ccaagaggag aacagcttca
    10081 atcaaaagta actttgaaag gaggtaacga atcatacttt tattcatttc ttacctcgca
    10141 atcaagtcat aaatcttggt gatgtttggc aacaaggttg ttactaggag cttgtctcca
    10201 acttccaaca tatcctcccc agttgggaaa atagtcttgc cctttcgaat aatggctgca
    10261 ataagaaccc cttttttcaa tttcagttga gaaagaggtt tggcagtcat tttattggct
    10321 tccttgatat ggaattgcag ggtttcaatt tggccattgg ctagatggtg catggcttga
    10381 aggtctgaat actgggcatt aactcgacca cgaataaagt gcataatcgt atctacagcg
    10441 atgcttttag gtgtgatgat acttgaaaaa tcaggcgcat tgataatctc gaggagactg
    10501 gtacgattga ccttagtaat atttttctgt acacctaccc tgtcaaggaa catagatgta
    10561 atcagatttt cctcatcgac acctgttaga gtcgcaacgg catcatagtg ttgagcactt
    10621 tcttccagca ggatatcttt tgcggttcca tctccttgaa cgatgtagag atttgggaat
    10681 ttctcgctaa agaagctggc gatttcagga ttgatttcaa tgacttttgt atcgatacga
    10741 ctatctttga gaataccaag tagataatag gcaattctac ctgccccaac gatgagaagg
    10801 ctcttcacgg cgcgtgattt aaaataatta tggaagagta tcatatcgac acggttacca
    10861 gtgacaaaga ttctatcttt atcctgtaca gtcatgtcac cgcttggaat gataatttga
    10921 tgatccctct ctatcgcaca gacaatgaca ttaccaaatt ttttacgaaa atcagaaatg
    10981 ggcatttggc aaagaccgct ggtggacttg acgacaaatt ccatgaggct aacgcgtcca
    11041 ccagcaaagc gttcgacaga cagggcgttg gggaagtcaa tgatattcgc gatagcgcgg
    11101 gcagccaaga gctcaggatt aacgataaga gaaaaaccga gaatattctt ttccttgaaa
    11161 taagagttag aatattcagg gttccgcacc cgaacgatag tttctttagc tcccattttc
    11221 ttggctagaa ctgctgcaat catgttgact tcatcgtgct cagtcagggc gataaagata
    11281 tcacaatctt ggacgctggc ttgctcaaga atggcaaaat cggccccgtt accaaggata
    11341 ccaatgatat caaagcgatt gacaatatga ttgagaacag cttcgtcttg ctcaatcagc
    11401 aaaacatcat gcttttctgc aaccaaggag cgacagaggg caaaaccaac ttttccccct
    11461 ccgacaagga taattttcat aataaaacct actttttcat gatgtaacta tcataccctt
    11521 tttcaagaaa aaatgcacct actagctaat aacaagagct tttagtgaaa attcgctata
    11581 aggtaaaact ataccctaac caattgaaat agctattagc gactttctct gaaatatggt
    11641 atgataaagg atatacaagg agataaaatg aataataatt tactggtatt acaatcagac
    11701 tttggtctgg ttgatggtgc ggtatcggct atgattggag tggctttaga agagtctcca
    11761 accttaaaaa tccatcactt gacgcacgat atcacgcctt ataatatttt tgaggggagc
    11821 tatcgtctct ttcagacggt ggattactgg cctgagggaa cgacgtttgt atcggttgtc
    11881 gatccaggtg tcggttcgaa acgtaagagt gtagttgcca agactgcaaa aaatcaatac
    11941 attgtcacgc cagataatgg gacgctttcc tttatcaaga aacacgttgg cattgtagcc
    12001 attcgtgaga tttctgaggt ggccaatagg cgtcaaaaca cagagcattc ttataccttc
    12061 cacggtcgtg atgtctatgc ctatactggt gctaaactgg ccagtggtca cattactttt
    12121 gaggaagtag ggccagagct cagtgtggaa cagattgtag agcttccagt cgtagcgacc
    12181 atcatagaag atcatctggt gaagggagcc attgatattc tggatgtgcg tttcggttcg
    12241 ctttggacct ctatcacacg ggaagaattt tacaagctgg aaccagaatt tggtgatcgt
    12301 tttgaagtga ccatctatca tgctgatatg ctggtctatc aaaatcaggt tgtctatggc
    12361 aaatcatttg cagatgtgag aattgggcaa cccatccttt acatcaactc tctctatcgt
    12421 ttaggtttgg ctatcaacca aggttccttt gccaaggcct ataatgtagg tgtcggttca
    12481 tcttggacca ttgaaataaa gaaaatagaa ggataaaata ggagaatagt atggaaatca
    12541 aatttacaat taaacaagtt gttgctgtcg gaattggcgc tgccctcttt gtcgtcatcg
    12601 ggatgatcaa cattccaacc cctgttccaa atacaagcat ccagcttcag tatgcggtac
    12661 aagcgctact ttctattatt tttggaccga ttatcggttt gcttgtcggg ttgattggtc
    12721 atgcaatcaa ggactctctt gctggttatg gtctatggtg gacttggatt atcgctagcg
    12781 gactttttgg tctagttgtg ggacttttta gaaagtacgt tcgagtgatc aatggtgttt
    12841 ttgactggaa agatattctt atttttaacc tcattcaact acttgcaaat gcccttgttt
    12901 ggggtgtctt ggcaccactt ggagatgttg tgatttatca agaagcggca gaaaaagtat
    12961 ttgcacaagg gattgttgcg ggaattgcca atggtgtatc tgtagctatt gcaggaactc
    13021 ttctcttact tgcctatgca ggaacccaaa ctcgtgcagg aagtttgaaa aagg
//
LOCUS       DAVBOD010000055        12973 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 640-05
            SAMEA1012484-rid20186543.denovo.055, whole genome shotgun sequence.
ACCESSION   DAVBOD010000055 DAVBOD010000000
VERSION     DAVBOD010000055.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012484
            Sequence Read Archive: ERR059358
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12973)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12973)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979948.1
            Genome Coverage       :: 595x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:03:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,266
            CDSs (total)                      :: 2,219
            Genes (coding)                    :: 2,091
            CDSs (with protein)               :: 2,091
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 71 of 128
            Pseudo Genes (incomplete)         :: 50 of 128
            Pseudo Genes (internal stop)      :: 33 of 128
            Pseudo Genes (multiple problems)  :: 22 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12973
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012484-rid20186543.denovo.055"
                     /strain="NIG 640-05"
                     /db_xref="taxon:1313"
     gene            87..3437
                     /locus_tag="VQ862_001723"
     CDS             87..3437
                     /locus_tag="VQ862_001723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000526318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HET3116030.1"
                     /translation="MGNFSFLLKNDEYESFSKPCIEAENMIATSTVATAFMARRALEQ
                     AVHWIYSHDSYLEAPYRATLSSLVWDDDFRDIVDSELHKQIVLLIRWGNHAAHGGEIK
                     EREAILALHHLYQFVNFIDYCYSNEFVERYFDEKCLPLSANIKYRETPQSMIKLQDSL
                     PELPDFHEQMAAQSVEVQETYTEKRETAAQRQDVPFHIDQLSEAETRKLFIDIDLRLA
                     GWIFEENCRVEIAVDGLKHGSGIGYCDYVLYGKNGKILAIVEAKKASVNPEVGEVQVK
                     EYAEALEKHIGYQPICFITNGLKHYILDGPNRRQIAGFYSQEELQLVMDRRHLQKPLE
                     DISSKIRDDISGRHYQKHAIASVCEAFSNHRRQALLVMATGAGKTRTAVSLVDILSRH
                     NWVKNVLFLADRTSLVKQAYDSFRKLLPDLSVCNFLEDKEGAQSSRMVFSTYPTMIGA
                     ISGQEEVNQRPFTVGHFDLIIIDESHRSIYQKYKSIFDYFDARIVGLTATPRQDLDKN
                     TYGFFNLENGVPTYAYDLEEAVKDGYLVAYHSIETKLKLPTDGLHYDDLSEEEKEHFD
                     SKFEDDSCEKDIDGSVFNSFVFNKSTVEIVLNELMTRGIQTASGDEIGKTIIFAKNHD
                     HAEYIRGIFNNRYPEKGSDYAQVIDYSIKHYQTLIDDFKIKEKYPQIAISVDMLDTGI
                     DVPEVVNLVFFKKVRSKTKFWQMIGRGTRLCKDLFGPEQDKENFLVFDYGDNFDYFRA
                     DPRDGEGRHIVSLTQRLFNIKVDLIRELQGLQYQEDQFARAYRQQLVSELQGRIESLN
                     ELDFRVRMVLDTVYSYRKLESWQNLTAVTSETIQKNLSPLLFDEDKEDEMARRFDLWL
                     LHIQLGQLTAKSSTVHISQVMKTARALSAIGNIPQVFEQAEIIRKVQEPEFWKEVNLS
                     DLEKIRLAIRDLLQFLDKTDRKPYYVNFEDRILSTVHETTAFLQVNDLRSYNEKVEHY
                     LKTHLDEESISKLYHNKKLTSDDMLALEKLLWEKLGSKADYQSHYENKAIPRLVREII
                     GLDRESANRIFSKFLSDENLNARQISFVKLIVDYIVENGFLETKVLTQEPFKSYGSVQ
                     LLFQHQLPVLRNIVQIIELINNRAGEAA"
     gene            3681..3782
                     /locus_tag="VQ862_001724"
                     /pseudo
     CDS             3681..3782
                     /locus_tag="VQ862_001724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            complement(4023..4493)
                     /locus_tag="VQ862_001725"
     CDS             complement(4023..4493)
                     /locus_tag="VQ862_001725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001043003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HET3116031.1"
                     /translation="MNKSEHRHQLIRALITKNKIHTQAELQALLAKNDIQVTQATLSR
                     DIKNMNLSKVREEDSAYYVLNNGSISKWEKRLELYMEDALVWMRPVQHQVLLKTLPGL
                     AQSFGSIIDTLSFPDAIATLCGNDVCLIICEDADTAQKCFEELKKFAPPFFFEE"
     gene            complement(4510..6783)
                     /locus_tag="VQ862_001726"
     CDS             complement(4510..6783)
                     /locus_tag="VQ862_001726"
                     /EC_number="3.4.14.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Xaa-Pro dipeptidyl-peptidase"
                     /protein_id="HET3116032.1"
                     /translation="MRFNQYSYINFPKENVLSELKKCGFDLQNTANHKDSLETFLRRF
                     FFTYQDTNYPLSILAADKKTDLLTFFQSEDELTADIFYTVAFQLLGFSYLVDFEDSDV
                     FRKETGFPIIYGDLIENLYQLLNTRTKKGNTLIDQLVSDGLIPEDNDYHYFNGKSLAT
                     FSNQDVIREVVYVESRVDTDQKGLSDLVKVSIIRPRFDGKIPAIMTASPYHQGTNDKA
                     SDKALYKMEGELEVKLPHKIELEKPQLNLVQPQGQAELIAEAEEKLTHINSSYTLNDY
                     FLPRGFANLYVSGVGTKDSTGFMTNGDYQQIEAYKNVIDWLNGRCRAFTDHTRQRQVK
                     ADWSNGKVATTGLSYLGTMSNGLATTGVDGLEVIIAEAGISSWYNYYRENGLVTSPGG
                     YPGEDFDSLAELTYSRNLLAGDYIRGNEAHQADLEKVKAQLDRKTGDYNQFWHDRNYL
                     LNAHKVKAEVVFTHGSQDWNVKPLHVYQMFHALPTHIHKHLFFHNGAHVYMNNWQSID
                     FRESINALLTKKLLGQETDFQLPTVIWQDNTAPQTWLSLDNFGGQENCKTFSLGQEEQ
                     AIQNQYPDKDFERYSKTYQTFNTELYQGKANQITINLPVTKDLHLNGRAQLNLRIKSS
                     TNKGLLSAQLLEFGQKKYLQPYPAILSARTIDNGRYHMLENLCELPFRPEAQRVVTKG
                     YLNLQNRNDLLLVEDITADEWMDVQFELQPTIYKLKEGDTLRLVLYTTDFEITIRDNT
                     DYHLTVDLAQSMLTLPC"
     gene            7129..10230
                     /locus_tag="VQ862_001727"
     CDS             7129..10230
                     /locus_tag="VQ862_001727"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000561528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit alpha"
                     /protein_id="HET3116033.1"
                     /translation="MIAQLDTKTVYSFMESVISIEKYVRAAKEYGYTHLAMMDIDNLY
                     GAFDFLEITKKYGIHPLLGLEMTVFVDEQEVNLRFLSLSSVGYQQLMKLSTAKMQGEK
                     TWSVLSQYLEDIAVIVPYFDRVESLELGCDYYIGVYPETLASEFHHPILPLYRVNAFE
                     SRDREVLQVLTAIKENLPLREVPLRSRQDVFISASSLEKLFQECFPQALDNLEKLISG
                     ISYDLDTSLKLPRFNPARPAVEELRERAELGLVQKGLTSKEYQDRLDQELSVIHDMGF
                     DDYFLVVWDLLRFGRSNGYYMGMGRGSAVGSLVSYALDITGIDPVEKNLIFERFLNRE
                     RYTMPDIDIDIPDIYRPDFIRYVGNKYGSKHAAQIVTFSTFGAKQALRDVLKRFGVPE
                     YELSAITKKISFRDNLKSAYEGNLQFRQQINSKLEYQKAFEIACKIEGYPRQTSVHAA
                     GVVISDQDLTNYIPLKYGDEIPLTQYDAHGVEASGLLKMDFLGLRNLTFVQKMQELLA
                     ETEGIHLKIEEIDLEDKETLDLFASGNTKGIFQFEQPGAIRLLKRVQPVCFEDVVATT
                     SLNRPGASDYINNFVARKHGQEEVTVLDSALEDILAPTYGIMLYQEQVMQVAQRFAGF
                     SLGKADILRRAMGKKDASAMHEMRASFIQGSIEAGHTAEKAEQVFDVMEKFAGYGFNR
                     SHAYAYSALAFQLAYFKTHYPAIFYQVMLNYSNSDYLIDALEAGFEVASLSINTIPYH
                     DKIANKSIYIGLKSIKGLSKDLALWIIEHRPYSNIEDFIAKLPENYLKLPLLEPLVKV
                     GLFDSFEKNRQKVFNNLANLFEFVKELGSLFGDAIYSWQESEDWTEQEKFYMEQELLG
                     IGVSKHPLQAIASKAIYPITPIGNLSENSYAIILVEVQKIKVIRTKKGENMAFLQADD
                     SKKKLDVTLFSDLYRQVGQEIKEGAFYYVKGKIQSRDGRLQMIAQEIREAVAERFWIQ
                     VKNHESDQEISRILEQFKGPIPVIIRYEEEQKTIVSPHHFVAKSNELEEKLNEIVMKT
                     IYR"
     gene            10313..11320
                     /gene="pfkA"
                     /locus_tag="VQ862_001728"
     CDS             10313..11320
                     /gene="pfkA"
                     /locus_tag="VQ862_001728"
                     /EC_number="2.7.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000820836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase"
                     /protein_id="HET3116034.1"
                     /translation="MKRIAVLTSGGDAPGMNAAIRAVVRQAISEGMEVFGIYDGYAGM
                     VAGEIHPLDAASVGDIISRGGTFLHSARYPEFAQLEGQLKGIEQLKKHGIEGVVVIGG
                     DGSYHGAMRLTEHGFPAIGLPGTIDNDIVGTDFTIGFDTAVTTAMDAIDKIRDTSSSH
                     RRTFVIEVMGRNAGDIALWAGIATGADEIIIPEAGFKMEDIVASIKAGYECGKKHNII
                     VLAEGVMSAAEFGQKLKEAGDTSDLRVTELGHIQRGGSPTARDRVLASRMGAHAVKLL
                     KEGIGGVAVGIRNEKMVENPILGTAEEGALFSLTAEGKIVVNNPHKADIELSSLNKSL
                     S"
     gene            11379..12884
                     /gene="pyk"
                     /locus_tag="VQ862_001729"
     CDS             11379..12884
                     /gene="pyk"
                     /locus_tag="VQ862_001729"
                     /EC_number="2.7.1.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate kinase"
                     /protein_id="HET3116035.1"
                     /translation="MNKRVKIVATLGPAVEIRGGKKFGEDGYWGEKLDVEASAKNIAK
                     LIEAGANTFRFNFSHGDHQEQGERMATVKLAEKIAGKKVGFLLDTKGPEIRTELFEGE
                     AKEYSYKTGEKIRVATKQGIKSTREVIALNVAGALDIYDDVEVGRQVLVDDGKLGLRV
                     VAKDDATREFEVEVENDGIIAKQKGVNIPNTKIPFPALAERDNDDIRFGLEQGINFIA
                     ISFVRTAKDVNEVRAICEETGNGHVQLFAKIENQQGIDNLDEIIEAADGIMIARGDMG
                     IEVPFEMVPVYQKMIIKKVNAAGKVVITATNMLETMTEKPRATRSEVSDVFNAVIDGT
                     DATMLSGESANGKYPLESVTTMATIDKNAQALLNEYGRLDSDSFERNSKTEVMASAVK
                     DATNSMDIKLVVTLTKTGHTARLISKYRPNADILALTFDELTERGLMLNWGVIPMLTD
                     APSSTDDMFEIAERKAVEAGLVESGDDIVIVAGVPVGEAVRTNTMRIRTVR"
BASE COUNT         4021 a         2204 c         2851 g         3897 t
ORIGIN      
        1 gcttgtgaga tagctataaa agtgtggaga aatagcttga aatttagtat aatatagcta
       61 aactatttgt ttaaagtgag aaaaaaatgg gaaattttag ctttctttta aaaaatgacg
      121 aatatgaatc tttttcaaaa ccttgcattg aagctgagaa tatgattgct acatcaactg
      181 tggctactgc ctttatggcg cgtcgtgctt tagagcaggc tgtccattgg atatatagtc
      241 acgattcata tttagaagct ccctatcgtg ctactctatc ttctttagta tgggatgatg
      301 attttaggga tatcgtagat tctgaactcc acaagcagat agttctgttg attcggtggg
      361 gaaaccatgc tgctcatggt ggtgaaatta aggaacgaga agcgatttta gctttgcatc
      421 atttgtatca gtttgttaat tttatcgatt attgttacag caatgagttt gtggagcgtt
      481 attttgatga gaagtgctta ccactttcag caaacatcaa ataccgagaa actccacaat
      541 ctatgataaa gttacaagac agtttaccag aactgcctga ttttcatgaa cagatggctg
      601 ctcagtccgt agaagttcaa gagacttata ctgaaaaacg tgagactgca gcgcaacggc
      661 aagatgtgcc tttccatatt gatcaattat ctgaggcaga gacaagaaag ctctttattg
      721 atatcgatct ccgtttagca ggatggatat ttgaagaaaa ctgtcgtgtt gagatagccg
      781 ttgatggtct caagcacggt tcaggaattg gttactgtga ctatgtactt tatggtaaaa
      841 atgggaaaat tttagcgatt gtagaggcta aaaaagcctc tgtcaatcca gaagtagggg
      901 aagtacaggt caaagaatat gctgaagctc ttgagaaaca tatcggctat cagccaattt
      961 gctttattac aaatggcttg aagcactata tacttgatgg tccgaaccgc cgccagattg
     1021 caggctttta ctctcaagaa gaattgcaat tagtgatgga tagacgtcat cttcaaaaac
     1081 cacttgagga tatttctagt aaaattaggg acgatatttc cgggcgtcac taccaaaaac
     1141 atgccattgc aagcgtttgt gaagctttct ctaatcatcg tagacaggca cttttggtta
     1201 tggcaactgg ggctgggaaa actcgtacag cagtttctct agttgatatc ttatcacgtc
     1261 ataactgggt aaaaaacgtt ctcttcttag ccgatagaac ttccttggtt aagcaagcct
     1321 atgattcgtt tagaaaatta ctcccagatc tttccgtttg taacttctta gaagataaag
     1381 aaggagctca atcaagtcgc atggtctttt caacttatcc gaccatgatt ggagcgatta
     1441 gtggtcaaga agaagtaaat caacgccctt tcactgttgg gcattttgac cttatcataa
     1501 ttgacgaatc tcaccgttct atttatcaga aatacaagtc catttttgat tattttgatg
     1561 caagaattgt aggcttaaca gctactccgc gtcaagattt agataaaaac acctatggat
     1621 tctttaattt ggagaatggg gttccaacat atgcatatga tttggaagag gctgttaaag
     1681 acggatattt agtagcctat cattctatcg aaaccaaact gaaactacct acggatggtc
     1741 tacattatga tgatttgtcc gaagaagaaa aggaacattt tgatagcaaa tttgaagacg
     1801 atagctgtga aaaagatatt gatgggagtg tatttaattc ctttgttttc aataaaagta
     1861 cagtagaaat tgttttaaat gaactcatga caagaggaat tcagacagcc tcgggtgatg
     1921 aaattggtaa aactattatt tttgctaaaa atcatgatca tgcggaatat atcagaggta
     1981 tttttaacaa ccgctatcct gaaaaaggga gcgactatgc tcaggtgatt gattatagta
     2041 ttaagcatta tcagaccttg attgatgatt ttaaaattaa ggagaagtat cctcaaattg
     2101 cgatttctgt cgatatgtta gatacaggta ttgatgtacc agaggttgtt aatttagtct
     2161 tcttcaagaa agtacgctct aaaactaagt tttggcagat gattggtcga ggaacccgtc
     2221 tatgtaaaga tttatttgga cctgagcagg ataaggaaaa cttcttggta tttgattatg
     2281 gggacaattt tgattatttt cgtgcagatc caagagatgg agagggtcgt cacattgttt
     2341 cgttgactca gcgtttattt aatatcaaag tggacttgat tcgagaactt cagggactcc
     2401 aataccaaga agatcagttt gcgagagcat accgtcagca gcttgtctcg gaacttcaag
     2461 gtcgtataga gagcttaaat gagttggact tcagggttcg tatggtttta gatacagttt
     2521 atagctatag gaaattggaa agttggcaga atctaactgc tgttacaagt gaaaccattc
     2581 aaaaaaatct ctctccgctt ttatttgatg aagataaaga agatgagatg gcgaggagat
     2641 ttgatttgtg gttgcttcat attcagttgg ggcaactgac agctaaatct tccactgttc
     2701 atatttccca agtgatgaag acggctagag ctctttctgc tattggcaat atcccgcagg
     2761 tttttgagca ggctgaaatt atcaggaaag tacaggagcc tgaattttgg aaagaagtta
     2821 acttgtctga tttggaaaaa attcgtcttg ctattcgaga tttattacag tttttggata
     2881 aaacagaccg taaaccctac tatgttaact ttgaagatcg tatactctcc actgttcacg
     2941 agaccacagc atttttgcag gtcaacgatc ttcggtctta caatgaaaaa gttgagcatt
     3001 atttgaaaac tcatctggat gaggagtcca tttctaagct ataccataat aaaaagttga
     3061 catctgatga tatgcttgca cttgaaaaat tgctctggga aaaattaggt agtaaagcag
     3121 actaccaaag tcattatgaa aataaggcaa ttccgagatt ggttcgtgag attattggct
     3181 tagatagaga gtctgccaat cgtatttttt ctaaattttt gtcggatgag aatcttaatg
     3241 ccaggcagat ttcatttgta aaattgattg tagactacat tgtagaaaat ggttttttag
     3301 agacgaaagt gttaacgcaa gagccgttta aatcttatgg ttctgttcaa ctactcttcc
     3361 aacaccaact accagtactt cgtaatattg ttcaaatcat tgaacttatc aataatcgag
     3421 ctggagaagc ggcttaaatt ctaaagtgat tgccatgctg agactcattt aaaattaaaa
     3481 agagtagaaa tttatgctat atatgagaag ttttattagg aagaatgtca tcgttttcct
     3541 agaatacagt atcagttgtt aagtggctga taaatttcaa agtagatact tgtaccacga
     3601 tgtttgttga tcgagttatt aacaaaagag ctactttgat tttaaagaaa tagaaaacaa
     3661 aaagccgagc aagaattcaa ttgcaggaga aaatgaaata atactcaatg aaaatcaaag
     3721 agcaaactag gaaattagct gcaggctgct caaaacactg ttttgaggtt gtagataaga
     3781 ctgacgaagt cagctcaaaa catggttttg aggttgtaga tgaaactgac gaagtcagta
     3841 accataccta cggcaaggcg acgttgacgc ggattgaaga gattttcgaa gagtataaat
     3901 cttcctagga taaagcaaaa cgcatagtat caagtgttga aaacccttga tactatgcgt
     3961 tttctgatgt taaagacttt ctaccagttt ttttaagcat aattgttagt tgtagtcatt
     4021 tattattctt caaagaaaaa tggtggggcg aattttttca gttcttcaaa gcacttttga
     4081 gcagtatctg catcttcaca gatgataaga cagacatcat taccacaaag ggtagcgata
     4141 gcgtcaggga agctcaaagt atcaatgata gaaccaaagg attgagccag tccaggaagg
     4201 gtttttagta ggacttggtg ttgaactggg cgcatccaga caagggcgtc ttccatgtag
     4261 agttcgagac gtttttccca ttttgagatg gaaccattgt taagaacata ataagcgcta
     4321 tcttcttcgc ggacttttga taggttcata tttttgatgt cgcgtgagag ggttgcctgg
     4381 gttacttgaa tgtcgttctt agcaagaagg gcttgcaact cagcctgtgt atgaatcttg
     4441 ttttttgtga taagagcgcg tataagttgg tggcggtgtt ctgatttatt cataataatg
     4501 taactccttt tagcaaggta aggtaagcat ggactgagcg aggtcgacag tcaagtggta
     4561 gtctgtattg tcacggatgg tgatttcaaa gtcagtagta tagaggacta aacggagagt
     4621 gtctccttct tttagcttgt aaatagttgg ctgcagttca aattgaacgt ccatccattc
     4681 atctgcagta atatcctcta ctaacagtaa atcatttcta ttttgtaaat taaggtaacc
     4741 ttttgtcacg actcgttgtg cctctggtct aaatggcaat tcacagagat tttccaacat
     4801 gtgatagcga ccgttatcaa tggttctagc acttaaaata gctggataag gttgtaggta
     4861 tttcttttgc ccaaattcta gcagttgggc agataagagc cccttgtttg tactggattt
     4921 gatacgaaga ttgagctgag cgcgaccgtt taggtggaga tctttagtca caggaaggtt
     4981 aatagtaatc tgattagctt tcccttgata gagctctgta ttgaaggttt ggtatgtctt
     5041 actatagcgc tcaaaatcct tatctgggta ctggttttga atagcttgct cttcttgacc
     5101 aagtgagaag gttttacagt tttcttgccc accgaagtta tcaagtgata accaagtctg
     5161 tggagctgta ttgtcctgcc agataacagt aggaagttga aagtctgttt cctgtcctag
     5221 taatttcttg gttaataagg catttatgga ctcacggaag tcaattgatt gccaattgtt
     5281 catgtaaaca tgggcaccat tatggaaaaa gagatgcttg tgtatatgag taggaagagc
     5341 atggaacatc tggtaaacat gaagtggttt gacattccaa tcctgagaac catgagtaaa
     5401 gacaacctct gcctttactt tatgggcatt gagcagataa ttgcggtcat gccaaaactg
     5461 attgtagtcc ccagtttttc ggtctagctg agctttcact ttttctaagt cagcttggtg
     5521 agcttcattg ccacggatat agtcgccagc taagagatta cgagaatagg ttaactcagc
     5581 aagggagtca aagtcctcac ctggataacc acctgggcta gtcaccagac cgttttcacg
     5641 gtagtagttg taccatgatg aaattcctgc ctcggcaatg ataacttcta aaccatcgac
     5701 tcctgtagtc gcaagaccat tggacatggt acctagatag gaaagtcccg ttgtagcaac
     5761 ttttccgttt gaccaatcag ccttgacttg acgctggcgc gtgtgatcag taaaggcacg
     5821 gcaacggccg ttaagccaat cgatgacatt tttataagcc tcgatttgct ggtagtctcc
     5881 attagtcatg aaacctgtcg agtctttggt accaacacct gagacataga gattggcaaa
     5941 gcctctcgga aggaagtagt cgtttagtgt atagctagag ttgatgtgag ttagcttttc
     6001 ctcagcctct gctataagct cagcttgacc ttggggttgg acgagattta gttgaggttt
     6061 ctctagctca atcttgtgag gaagcttaac ctcaagctcg ccctccatct tgtagagagc
     6121 cttgtcacta gccttgtcat tggttccctg atgataaggg ctggctgtca tgatggcagg
     6181 gatttttcca tcaaaacgag ggcgaataat gctaaccttt actaggtctg atagcccttt
     6241 ttggtcagta tcgacacgag actcaacgta aacgacttca cgaatgacat cctggttaga
     6301 aaaagtagcc aaactcttgc cgttaaagta gtggtagtca ttatcctccg gaataagacc
     6361 atcactaaca agttggtcga taagagtatt tccttttttg gtgcgagtat tgagtaactg
     6421 atagagattt tcaatcaagt caccatatat aatgggaaat ccagtttctt tacgaaaaac
     6481 gtcactatct tcgaagtcaa ccaaataaga aaagcctaaa agttgaaaag caacagtata
     6541 aaaaatatct gctgtcagtt catcttctga ttgaaaaaat gtcagcaggt ctgttttttt
     6601 atcagctgct aggatagaaa gtgggtagtt ggtgtcttga taagtgaaaa agaaacgacg
     6661 taaaaaggtt tcaagtgagt ctttgtgatt ggctgtattt tgtaaatcaa agccacattt
     6721 ttttagctca gataagacat tttcttttgg aaaattgata taactatatt gattaaaacg
     6781 catagaacct ccatatagaa tgacagttaa ggttattata tcaaaaaaaa agcagaaagg
     6841 gaattgttaa cttcaaaagg aaataatcca ataaaaatga ataaagtact aaattcaata
     6901 tagagaacag agtaacaata agaataatag atagggtata aaagttctag gagatttata
     6961 ttatatgctt tctattttta tatacaatat agtataaata taaaaatgat gacaaaaata
     7021 caaatgaata gaaaataaat tagtaagctg atgaaatttt tctcaagaga agccatttat
     7081 aggtgaaaat ggtataatat agtgagaagg atagaggaga agtgtaaatt gatcgcacaa
     7141 ctagatacaa aaacagtcta tagttttatg gaaagcgtca tttcgatcga aaagtatgtg
     7201 agagcagcta aagaatacgg ctacactcat ttggctatga tggatattga caatctttat
     7261 ggcgctttcg actttctaga gattacaaaa aaatacggca ttcatccttt gctagggctt
     7321 gaaatgacag tgtttgtaga tgaacaggaa gtgaatttgc gctttttatc tctatctagt
     7381 gtgggctatc agcagttgat gaagctttcg acagccaaga tgcaggggga gaaaacttgg
     7441 tcagtcctgt cccagtacct ggaggatatc gcggtcattg tgccttattt tgatagagtt
     7501 gagtcgttag aactaggctg tgattactat ataggggttt atccagaaac actagcaagc
     7561 gaatttcatc atcctatctt acctctttat cgggtcaacg cttttgaaag cagggataga
     7621 gaagttcttc aagttttaac agcgattaaa gaaaatctac cgctcagaga agttcccttg
     7681 cgttcgagac aagatgtctt tatatcagca agttctttag agaaactatt ccaagagtgt
     7741 tttccgcaag ctttggacaa tttagaaaag cttatttcag gcatttctta cgacttggat
     7801 actagtctga aactgcctcg ttttaatcca gctagaccag cagtagagga gttgagagag
     7861 cgtgctgaac tggggcttgt tcagaagggg ttgactagta aagaatatca agatagacta
     7921 gaccaagaat tgtctgttat tcatgatatg ggctttgatg attatttctt ggttgtttgg
     7981 gatttgttgc gttttggacg atcgaatggc tattatatgg gaatgggaag gggttctgca
     8041 gtaggcagtt tggtttctta tgccttagac atcacgggga ttgacccagt agagaaaaat
     8101 ctgatttttg aacgctttct taatcgtgaa cgctatacca tgcctgatat tgatattgat
     8161 atcccagata tttatcgtcc agattttatc agatatgttg gtaataaata tggtagtaaa
     8221 catgcggcac aaatcgttac tttttcaacc tttggagcca agcaagctct tcgagatgtc
     8281 ttgaaacgct ttggtgtgcc agagtatgaa ttatctgcaa ttactaagaa aatcagtttt
     8341 cgtgacaatc ttaagtcggc ctatgagggc aatctccagt ttcgtcagca aatcaatagt
     8401 aagttagaat accaaaaagc ttttgagatt gcttgcaaga tagagggcta tccaaggcaa
     8461 acctctgtcc atgcggctgg tgttgtaatt agtgaccaag atttaaccaa ctacattcct
     8521 ctaaagtatg gtgatgaaat tccactgact cagtatgatg ctcatggagt tgaggctagc
     8581 ggacttttga agatggactt tctgggacta cgaaatttga cctttgtcca gaagatgcaa
     8641 gagttgcttg ctgaaacaga aggtattcac cttaaaattg aagaaataga tttggaagac
     8701 aaagaaacgt tagatttatt tgcctctgga aatacaaaag gtatctttca atttgagcaa
     8761 cctggtgcca ttcgcttgct caaacgtgtt caaccagtct gttttgaaga tgtcgtagca
     8821 actacttctc taaatcgacc aggtgcaagt gactacatca ataattttgt ggcaaggaag
     8881 catgggcagg aagaagtgac tgttctagat tcagctctgg aggatatttt ggctccaact
     8941 tatggcatta tgctctatca ggagcaggtt atgcaggttg ctcagcgatt tgctggattt
     9001 agtcttggga aggccgatat tttgcgtcga gctatgggta aaaaggatgc ctctgctatg
     9061 catgagatga gggcttcctt tattcaaggc tccatagaag caggccatac tgcggaaaaa
     9121 gcagagcagg tttttgatgt tatggagaag tttgcaggtt atggatttaa tagatctcat
     9181 gcctacgcct actcagcctt ggccttccag ttggcttatt tcaaaacgca ttatccagcc
     9241 attttttatc aggtcatgtt aaattattcc aacagtgatt acttaataga tgcacttgaa
     9301 gcaggttttg aagtagcctc tctatccatc aatactattc cctatcacga taaaattgcc
     9361 aacaagtcta tctatatagg tttgaaatcg attaaggggc tcagcaagga cttggcgctt
     9421 tggattattg aacatagacc ttattctaac attgaagatt ttatagctaa attacctgag
     9481 aattatctga aacttcctct gctagaacct ttggtaaaag ttggtctttt cgattcattt
     9541 gaaaaaaatc gtcaaaaagt atttaataac ttagctaatc tatttgaatt tgtgaaagag
     9601 ttgggaagtt tgtttggaga tgctatttat agttggcagg aatcggaaga ttggacggaa
     9661 caagaaaaat tttatatgga acaagagctt ttagggatag gtgtcagcaa acatccacta
     9721 caagctattg caagtaaggc tatttacccg attaccccaa tcggaaattt gtcagaaaat
     9781 agctatgcta ttattttggt tgaagttcag aaaataaaag tgattcgtac caaaaagggt
     9841 gaaaatatgg ccttcttaca ggcagatgat agtaagaaaa aattggatgt cactctcttt
     9901 tcagacttat atcgtcaggt tggacaggaa ataaaagagg gagccttcta ctatgtaaaa
     9961 ggaaaaatac aatcacgtga tggccgtttg caaatgattg cacaagaaat aagagaagca
    10021 gttgctgaac gcttttggat acaggtgaaa aatcatgaat cggatcaaga aatttcacgt
    10081 attttagaac aatttaaagg cccaatccca gtcatcatcc ggtatgaaga ggaacagaaa
    10141 accatcgttt ctccccatca ttttgtagct aaatccaatg aattagagga gaaattgaat
    10201 gaaatcgtta tgaaaacgat ttatcgctaa aaatacggaa aatagaagaa ttttaaaatc
    10261 aaatgtgata taatcaagaa gaatgttaaa agaaaaagga gcataaacca atatgaaacg
    10321 tattgctgtt ttgactagtg gcggagacgc acctggtatg aacgctgcta tccgtgcagt
    10381 tgttcgtcaa gcaatttcag aaggaatgga agtgtttggt atctatgacg gatatgctgg
    10441 tatggttgcc ggtgaaattc atcccctaga tgcagcttca gtaggagaca tcatttctcg
    10501 tggtggtact tttcttcact cagctcgtta cccagagttc gctcaacttg aagggcaact
    10561 taaagggatt gagcaattga aaaaacacgg aattgaaggt gtagttgtta tcggtggtga
    10621 cggatcttac cacggcgcta tgcgtttgac tgaacatggc ttcccagcta ttggtcttcc
    10681 aggtacaatc gataacgata tcgttggtac tgactttaca atcggttttg acacagcggt
    10741 tactactgcc atggacgcta tcgataagat tcgtgataca tcatcaagtc accgtcgtac
    10801 ttttgtaatc gaagttatgg gacgtaacgc tggtgatatc gctctttggg ctggtattgc
    10861 aactggtgct gatgaaatca tcatccctga agcaggcttc aagatggaag atatcgtagc
    10921 aagcatcaaa gctggttatg aatgtggtaa aaaacacaat atcatcgtct tagctgaagg
    10981 tgtgatgtca gcggctgaat ttggtcaaaa acttaaagaa gctggagata caagcgacct
    11041 tcgtgtaaca gaacttggac atattcaacg tggtggttct ccaactgcgc gtgaccgtgt
    11101 tttagcgtca cgtatgggtg cacatgctgt taaacttctt aaagaaggta tcggtggtgt
    11161 tgcggttggt attcgtaacg aaaaaatggt tgaaaatcca attcttggta ctgcagaaga
    11221 aggggcattg tttagcctta ctgcagaagg taagattgtg gttaacaacc cgcacaaagc
    11281 cgatattgag ctatctagct tgaataagag cttgtcataa tttacaattt agttaataag
    11341 accaaaaagg tcatatatat aaaggagtca caaaaatcat gaacaaacgt gtaaaaatcg
    11401 ttgcaacttt gggtcctgcg gtagaaatcc gtggtggtaa aaaattcggt gaggacggat
    11461 actggggtga aaaacttgat gttgaagctt cagctaaaaa cattgctaaa ttgattgaag
    11521 ctggtgctaa cacattccga ttcaacttct cacacggcga ccaccaagaa caaggtgagc
    11581 gtatggcaac tgttaaactt gcggaaaaaa ttgcaggtaa aaaagttggt ttccttcttg
    11641 atacaaaagg acctgaaatc cgtacagaat tgttcgaagg tgaagctaaa gaatattcat
    11701 acaaaactgg tgaaaaaatt cgtgttgcaa ctaaacaagg aatcaaatca actcgtgaag
    11761 tgattgcgtt gaacgttgct ggtgctcttg atatctatga tgatgttgaa gttggtcgtc
    11821 aagttttggt tgacgatggt aaacttggtc ttcgtgtggt tgctaaagat gatgcaactc
    11881 gtgaatttga agttgaagtt gaaaacgatg gtatcatcgc taaacaaaaa ggtgtgaaca
    11941 tccctaacac taaaattcct ttcccagctc ttgctgaacg cgataacgac gatatccgtt
    12001 tcggtcttga acaaggtatc aacttcatcg caatttcatt cgtacgtact gcaaaagatg
    12061 tgaacgaagt tcgtgcaatc tgtgaagaaa ctggaaacgg acatgttcaa ttgttcgcta
    12121 aaatcgaaaa ccaacaaggt atcgataact tagacgaaat catcgaagca gctgatggta
    12181 ttatgattgc tcgtggtgat atgggtatcg aagtaccgtt cgaaatggtt ccagtttatc
    12241 aaaaaatgat tatcaagaaa gtcaatgctg caggtaaagt tgttatcact gcaacaaaca
    12301 tgcttgaaac aatgactgaa aaaccacgtg caactcgttc agaagtatca gacgtattca
    12361 acgctgttat cgacggaact gacgctacaa tgctgtcagg cgagtctgca aacggtaaat
    12421 acccactcga gtcagtaact acaatggcta caatcgacaa gaacgctcaa gctcttctta
    12481 atgaatacgg acgtcttgat tcagattcat ttgagcgtaa ctctaagaca gaagtaatgg
    12541 cttctgctgt taaagatgct actaactcaa tggatatcaa attggttgta actcttacta
    12601 agacaggtca tactgcacgt ttgatttcta aataccgtcc aaatgctgac atcttagcat
    12661 tgacatttga cgaattgaca gaacgtggct tgatgttgaa ctggggtgtt atcccaatgt
    12721 tgacagatgc tccatcttca actgacgata tgttcgaaat cgctgaacgt aaagcggtag
    12781 aagcaggtct cgttgagtca ggcgatgata tcgttatcgt tgctggtgtg ccagtaggag
    12841 aagctgttcg cacaaacaca atgcgtatcc gcacagtacg ttaagaaaaa tataaaaacc
    12901 tatcatatcc agctttctag cctgtatgat gggctctttt tttgtccagg gggcaaaact
    12961 ttcataatgg att
//
LOCUS       DAVBOD010000056        12573 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 640-05
            SAMEA1012484-rid20186543.denovo.056, whole genome shotgun sequence.
ACCESSION   DAVBOD010000056 DAVBOD010000000
VERSION     DAVBOD010000056.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012484
            Sequence Read Archive: ERR059358
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12573)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12573)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979948.1
            Genome Coverage       :: 595x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:03:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,266
            CDSs (total)                      :: 2,219
            Genes (coding)                    :: 2,091
            CDSs (with protein)               :: 2,091
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 71 of 128
            Pseudo Genes (incomplete)         :: 50 of 128
            Pseudo Genes (internal stop)      :: 33 of 128
            Pseudo Genes (multiple problems)  :: 22 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12573
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012484-rid20186543.denovo.056"
                     /strain="NIG 640-05"
                     /db_xref="taxon:1313"
     gene            complement(251..433)
                     /locus_tag="VQ862_001730"
     CDS             complement(251..433)
                     /locus_tag="VQ862_001730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000268343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3116036.1"
                     /translation="MAVIFKNVLIEEKTEEEKQHILSILNGEYDLSDDVSCRLRRLNE
                     ESKRLEVFVKETNSLV"
     gene            complement(649..1881)
                     /locus_tag="VQ862_001731"
     CDS             complement(649..1881)
                     /locus_tag="VQ862_001731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide sugar dehydrogenase"
                     /protein_id="HET3116037.1"
                     /translation="MKIAVAGTGYVGLSIAILLAQHHQVVAVDIIPEKVELINKKKSP
                     IQDDYIEKYLAEKELNLVATLNAEEAYENADFIVIAAPTNYDPKKNFFDTSSVEAVIE
                     AVMKYNPDAIIIIKSTVPVGYTKSVRRKFLTDNIMFSPEFLRESKALYDNLYPSRIII
                     GTDKDDKDLVKSAEIFVKMLQEGAVKENIETLYMDFTEAEAVKLFANTYLALRVSYFN
                     ELDTYSEMKGLDTQAIIDGVCLDPRIGSHYNNPSFGYGGYCLPKDTKQLLANYSDVPQ
                     EMITAIVQSNRTRKDYIADRILDLAGSYVGNDFYKPDKEKEIVVGIYRLTMKSNSDNF
                     RQSSIQGIMKRLKAKGVTIIIYEPTLESGTTFYGSQVVNDFEIFKKSSQVIVANRFDE
                     TLEDVRGKVYTRDIFKRD"
     gene            complement(1910..2980)
                     /gene="gla"
                     /locus_tag="VQ862_001732"
     CDS             complement(1910..2980)
                     /gene="gla"
                     /locus_tag="VQ862_001732"
                     /EC_number="5.1.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001214397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucuronate 4-epimerase Gla"
                     /protein_id="HET3116038.1"
                     /translation="MRGKTILITGVAGFIGSNLVRKLLELEGTMTIIGLDNLNDYYDI
                     ALKDYRLLQLNKLIQDYPEKNWIFIKGDIADKMLINKIFKSYHPQIVVNLAAQAGVRY
                     SITNPDVYIESNIVGFHNVLEACRHSYEIYDGGVEHLVYASSSSVYGGNKKIPFATED
                     KVDNPISLYAATKKTNELQAYAYSKIYNIPSTGLRFFTVYGPAGRPDMAYFGFTDKLR
                     SGSDIEIYNHGNCKRDFTYIDDIVEGIVRVMQSAPKKLVGSDNLPLAPYKVYNIGNSK
                     PENLLDFVDVLQQELIKAGVLPENYDFDSHKKLVPMQPGDVPVTYADTSDLERDFGFK
                     PKTSLREGLRKFAEWYKDYYNV"
     gene            complement(3048..4217)
                     /locus_tag="VQ862_001733"
     CDS             complement(3048..4217)
                     /locus_tag="VQ862_001733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide flippase family protein"
                     /protein_id="HET3116039.1"
                     /translation="MRLSKKYWFALTSKFLLILLTLLSSIIINRGLGVEKKGDYAYVM
                     NLVEIFYILGGVGLGQAYSTFKRNHSNEYQNKFVFLTFIQGLLFGIIGLIIVLADVPI
                     DYGGVIIVLSSLSIMRTNLTMIAVIENSIKRNKIVLGVSVVYSVMLVLLLLFHLVSIE
                     MVFLVYAINEFLRIILFLYYYNMFPVFEHISIKEFFTIYKFGFLSMILTLLITFNYSI
                     DIIMLKQMSSSYNVGIYSVAVTFSNMFLMVPDSFKEILFGDSAKRTFEKNKAINAIKV
                     SFLFMILLIIGFLSFGEFAITLLYGSSYIKAFPITLVIFLGSLSMIFFKILQPIYISQ
                     GKQSVAIKILSVSALINISLNWYLIPNYQITGAAIASAISYTVCGLFFIIDYLRN"
     gene            complement(4403..5707)
                     /locus_tag="VQ862_001734"
     CDS             complement(4403..5707)
                     /locus_tag="VQ862_001734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000672721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide repeat unit polymerase"
                     /protein_id="HET3116040.1"
                     /translation="MKFSLQSNDIKNKIILLVGVVFSGTLILCSENNDVTIPLFSMIF
                     LSFMAMIIVKFNIFHPYVWYSSFFTIYSISYPLLYRMEYINYGYTKDLIFMQWLALAT
                     LLLTLPSKAIVLSERKINLNNNNYLLFLNNMNTFITTVAIIYLLGSGFRNKGEIYSGA
                     NIVIMLVFSLVYFMILIHTYQLFIQLSTKKWRLLNCNTNTAIVICLFSIVTGERDYMF
                     TLFILDVIILFYFHKIKRFYLVMLVPLAALLIPLSAVFKYTLLSGQVSSINTNNIWFD
                     LLDGEFVSASRNLQILILHNMGNYFEGRSFFNDIVRIFYNTGYSNQTWFMDTFFPNVH
                     STKYGFTLVGEGYVNGGYFGIVMIFMLTGFLMRFLYINAQRNIYGMLIYLYMIPIFIY
                     STRADFANILSPLLKYAILGTLVIVFINRMVLISPLDEMGGE"
     gene            complement(5824..6978)
                     /locus_tag="VQ862_001735"
     CDS             complement(5824..6978)
                     /locus_tag="VQ862_001735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000862350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HET3116041.1"
                     /translation="MKVFIATEFRCTIYKNEIYLKPKAYFIYERYAKAFGEIVLCSRY
                     EKVESYPEGYHKANFINKFIPIEGLHQVLFGQNKNKIIEGMIDSDLIVVRIPSIIGSK
                     TADYALKIGKPYLTEIMGDAWDSYWYHSLKGKLLAPYIYAKTKSIVKNANYCIYVTEK
                     YLQDRYPNIKSNIVASNVNITSVENRSLKSRLYKLKKFNPQKISIMTTASVNVRAKGH
                     RFVLEAMKRLEIQGILLDYYLAGDGDQSFLKKKAEELGVANRIHFLGELTTSQIYEYL
                     DKVDLYIQPSLQEGLPRAVIEAMSRACPCIGSNKAGIPELLGPHCLFTPSSSQAIAGS
                     IIDFISMDKEKMVIKQFEFSKKFLSSVLNKRRSDYFAQIRRELNNSDGLD"
     gene            complement(6975..7526)
                     /locus_tag="VQ862_001736"
     CDS             complement(6975..7526)
                     /locus_tag="VQ862_001736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001079795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyltransferase"
                     /protein_id="HET3116042.1"
                     /translation="MNRIIKNIVGLLRANICLILLKVCRNKDLTFHYFLKFGKNVTVE
                     QESNAKLILGKKIRVNAGGVLKVRKGAKLKISDDVFLSNNCMIACRKYIDIKSGVKCG
                     PGVLIYDHDYDVSVPGGLKAKKFKTAPVMIGENVWIGANSIVLKGVSIGENSVVAAGS
                     VVTKDIPADTIFIQKRLSREMKL"
     gene            complement(7519..8655)
                     /locus_tag="VQ862_001737"
     CDS             complement(7519..8655)
                     /locus_tag="VQ862_001737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001053205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HET3116043.1"
                     /translation="MNLQKKKIMLITNHDDDIYCFRKEVIESLVEYGYEVLVSCPYGD
                     KIELMKSIQFEYEDITIDRRGINPLKDIRLFLSYIRLLRKYRPDVVLTYTVKPNVYAS
                     LAATILGIKYINNVTGLGSVLTMGSCVRSLVLLLFRISFRKSNCVFFQNEYNMKMLKT
                     LGLILGDSKLIPGSGVNIEKYPVQQYPNGGNGIQGETIVFNFIGRILKEKGIDTYLAA
                     AQIIKSRYPKTEFNIIGFIEPTESNYELKICDLEKKGIVYYLGQQKDVIPHITRSHAI
                     IHPSVYGEGMSNVLLENASSGRVLITTDNPGCKEIVKDRETGYIFQGGNVEELVSILE
                     VFLGLENEKRKEMGLQGRMYIEQYFSRQIIIDAYLDKIKGALDE"
     gene            complement(8796..9461)
                     /gene="cpsD"
                     /locus_tag="VQ862_001738"
     CDS             complement(8796..9461)
                     /gene="cpsD"
                     /locus_tag="VQ862_001738"
                     /EC_number="2.7.10.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001845065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis tyrosine autokinase
                     CpsD"
                     /protein_id="HET3116044.1"
                     /translation="MPTLEIAQKKLEFIKKAEEYYNTLCTNIQLSGDKLKVISVTSVN
                     PGEGKTTTSVNIAMSFARAGYKTLLFDGDIRNSVMSGFFKSREKITGLTEFLSGTADL
                     SHGLCDTNIENLFVVQSGSVSPNPTALLQSKNFNDMIETLRKYFDYIIVDTPPIGIVI
                     DAAIITQKCDASILITATGEANKRDVQKAKQQLEQTGKLFLGVVLNKLDISVDKYGVY
                     GRK"
     gene            complement(9471..10163)
                     /gene="cpsC"
                     /locus_tag="VQ862_001739"
     CDS             complement(9471..10163)
                     /gene="cpsC"
                     /locus_tag="VQ862_001739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000664160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsular polysaccharide biosynthesis protein
                     CpsC"
                     /protein_id="HET3116045.1"
                     /translation="MKEQNTLEIDVLQLFRALWKRKLVILLVAIITSSVAFAYSTFVI
                     KPEFTSTTRIYVVNRNQGEKPGLTNQDLQAGAYLVKDYREIVLSQDVLEEVISDLKLD
                     LMPKGLANKIKVTVPVDTRIVSVSVSDRVPEEASRIANSLREVAAQKIISITRVSDVT
                     TLEEARPAISPSSPNIKRNTLIGFLAGVIGTSVIVLLLELLDTRVKRPEDIENALQMT
                     LLGVVPNLGKLK"
     gene            complement(10172..10903)
                     /locus_tag="VQ862_001740"
     CDS             complement(10172..10903)
                     /locus_tag="VQ862_001740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-protein phosphatase CpsB"
                     /protein_id="HET3116046.1"
                     /translation="MIDIHSHIVFDVDDGPKSREESKALLAESYRQGVRTIVSTSHRR
                     KGMFETPEEKIAENFLQVREIAKEVADDLVIAYGAEIYYTLDALEKLEKKEIPTLNDS
                     RYALIEFSMHTSYRQIHTGLSNILMLGITPVIAHIERYDALENNEKRVRELIDMGCYT
                     QINSYHVSKPKFFGEKYKFMKKRARYFLERDLVHVVASDMHNLDSRPPYMQQAYDIIA
                     KKYGAKKAKELFVDNPRKIIMDQLI"
     gene            complement(10905..12350)
                     /locus_tag="VQ862_001741"
     CDS             complement(10905..12350)
                     /locus_tag="VQ862_001741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000091082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HET3116047.1"
                     /translation="MSRRFKKSRSQKVKRSVNIVLLTIYLLLICFLLFLIFKYNILAF
                     RYLNLVVTALVLLVALVGLLLIIYKKAEKFTIFLLLFSILVSSVSLFAVQQFVGLTNR
                     LNATSNYSEYSISVAVLADSKIENVTQLTSVTAPTGTDNENIQKLLADIKSSQNTDLT
                     VNQSSSYLAAYKSLIAGETKAIVLNSVFENIIESEYPDYASKIKKIYTKGFTKKVEAP
                     KTSKNQSFNIYVSGIDTYGPISSVSRSDVNILMTVNRDTKKILLTTTPRDAYVPIADS
                     GNNQKDKLTHAGIYGVDSSIHTLENLYGVDINYYVRLNFTSFLKMIDLLGGVDVHNDQ
                     EFSALHGKFHFPVGNVHLDSEQALGFVRERYSLTDGDRDRGRNQQKVIVAIIQKLTST
                     EVLKNYSSILQGLQDSLQTNIPIETMIDLVNTQLESGGNYKVNSQDLKGTGRMDLPSY
                     AMPDSNLYVMEIDDSSLTVVKAAIQDVMEGR"
BASE COUNT         4238 a         2433 c         1654 g         4248 t
ORIGIN      
        1 aattcactta cttcatatta catttagcat gaaatgaaat aagcgaattc tactttgttt
       61 gcatacaatt aaaaatcaat tcctaaggat gttttaaata actgtgtaaa aggcataatt
      121 tcaccatttc ttagtttttc aatgctaaat tacatagtaa ctggagagct attagaaatc
      181 tctaacttcc tcatagttaa aaaatgacaa tgagatactt attgatttca attcattaac
      241 agaatacgaa ctagacaagt gagttcgtct ccttaacaaa cacttccaag cgtttacttt
      301 cctcattcag tcgtcgtaat ctacaactta catcatcaga taagtcatac tcaccattta
      361 gaatagatag aatatgttgt ttttcttctt cagtcttctc ttcaataagc acatttttaa
      421 aaattactgc cattatcagc acctcacttc gaaggaatat atgcaactat atcctattaa
      481 gtcaatctct actgacaaaa gaagtatatt tacttcacta agtgcgagcg agaatataga
      541 aatatcttta ttgttttaga tgagttgtcg ctatcctcca gctagttttt aactattcta
      601 tcattcaaat gatatagatt attagggact agaaatatac aaattgattt aatctctctt
      661 aaaaatatcc ctagtataaa ctttacccct cacatcttct aaagtctcat caaaacgatt
      721 tgcaacaatc acttgactag atttcttaaa tatttcaaaa tcattaacta cttgactacc
      781 atagaaagta gtaccacttt caagagttgg ttcgtaaata ataatagtaa caccttttgc
      841 tttcaaacgc ttcataatac cttgaataga agattgtcta aaattatctg aattactttt
      901 cattgttaaa cgataaattc ctacaacaat ctctttttct ttatctggtt tatagaaatc
      961 attgcctaca taagatccag caagatctaa aatacgatct gcaatataat cttttcttgt
     1021 ccgattactt tgtactatag ctgttatcat ttcttgtgga acgtcagaat aatttgcaag
     1081 aagttgcttg gtatctttag gaagacagta acccccataa ccaaaagaag gattattgta
     1141 gtgagaacct attctcggat ctaaacaaac tccatcaata atcgcttgag tatctagtcc
     1201 tttcatctca gaataagtat ctaactcgtt aaaataggaa acccggaggg caagataggt
     1261 attagcaaaa agttttactg cttcagcttc tgtaaaatcc atatacaatg tttcaatatt
     1321 ttctttcact gcaccttcct gaagcatttt tacaaaaatt tcagcagact ttaccaaatc
     1381 tttatcatct ttatctgtac ctataataat tcgactcgga tataggttat catataacgc
     1441 ttttgactcc cgtaaaaact caggactaaa cataatattg tctgtaagaa atttcctccg
     1501 tactgacttt gtatatccaa caggaacagt acttttaatt attataattg catcaggatt
     1561 atatttcata actgcttcaa tgacagcctc gactgaagat gtatcgaaaa aatttttttt
     1621 cggatcataa ttagttggag ccgcaataac tataaaatcc gcattctcat atgcttcctc
     1681 tgcattcaat gtagctacga gattcaattc tttttccgcg agatattttt ctatataatc
     1741 gtcttggata ggggacttct ttttattgat taactcaact ttctcaggaa tgatatctac
     1801 ggcaacaact tgatgatgtt gagccagtaa gattgcaata gataatccaa catatcctgt
     1861 acctgctact gctattttca taattttttc ctttctcaaa acactctcgt tatacattat
     1921 agtagtcttt ataccactct gcaaactttc tcaaaccttc tcgtaaagaa gtttttggtt
     1981 taaaaccaaa atctctctct aaatcacttg tatctgcata agtaacagga acatcgcctg
     2041 gttgcatagg aactaatttt ttatgactat caaaatcata attttccggc aaaactcctg
     2101 ccttgattag ctcctgttga agaacatcca caaaatctaa caaattttcg ggtttactat
     2161 tcccaatatt gtacacttta tatggggcta acggtaaatt atcagatccc actagtttct
     2221 tcggagctga ttgcatgacc cttactatcc cctcaacgat atcatctata taagtaaaat
     2281 ctcgtttaca attaccatga ttataaatct caatatcgga accacttcgc aatttatctg
     2341 taaatccaaa ataggccata tctgggcgcc cagcaggacc ataaactgta aaaaagcgta
     2401 agcctgtcga aggaatattg taaatctttg aataagcata cgcttgaagt tcatttgttt
     2461 ttttagtcgc agcatatagt gaaataggat tgtctacctt atcttctgtt gcaaacggga
     2521 tttttttatt tccaccatat accgatgagg acgatgcata aactaagtgt tccacaccac
     2581 catcatatat ctcatacgaa tgacgacaag cttccaacac attatgaaag ccaacgatat
     2641 tactttctat atatacatct ggatttgtaa tggagtagcg tactcctgcc tgggcagcta
     2701 gattaacaac aatctgagga tgataactct taaaaatctt attaataagc attttatctg
     2761 caatatcacc cttgataaat atccagtttt tttctggata atcctgaatt agcttattaa
     2821 gttgaagcaa tcgataatct ttaagtgcaa tatcatagta atcattcaaa ttgtccaaac
     2881 caatgattgt catcgttcct tctaattcca ataatttcct aaccagattt gatccaataa
     2941 aaccagctac tcctgtaatt agaattgttt ttcctctcat atcataatac ctcttgttat
     3001 ttttatattt tcatccacta atacacattc tttaacaact attataatca atttctaaga
     3061 taatctataa taaaaaacaa accacataca gtataagaga ttgctgatgc tatcgcagct
     3121 cctgtaattt ggtagttagg aattaagtac cagtttaaac ttatatttat caaagccgac
     3181 acagataaaa tttttatagc tacactctgt ttaccctgag atatataaat tggttgtaaa
     3241 attttaaaga aaatcatcga taagcttcct aaaaaaatga ctaatgttat aggaaatgcc
     3301 tttatataac tggaaccata aaggagcgta atcgcaaatt ctccaaaaga aagaaatcca
     3361 ataattaata aaatcataaa tagaaatgat acttttattg catttattgc tttatttttc
     3421 tcaaaagttc ttttagccga atcaccaaat aaaatctctt taaatgagtc tggaaccatc
     3481 aaaaacatat tagaaaacgt aactgcgaca ctgtatatac ctacattata actactagac
     3541 atttgcttca acattatgat atcaatacta taattaaatg taattaatag agtaagaatc
     3601 atagaaagaa atccaaactt atatatagtg aaaaattctt taatactaat atgttcaaaa
     3661 actgggaaca tattgtaata gtataaaaat aaaatgatac gtaaaaattc attaatagca
     3721 tataccaaaa ataccatctc tatagaaact aaatgaaata gtaacaacaa tactagcata
     3781 acggaatata ctacgcttac tcctaataca atcttattcc tctttatact attttctatt
     3841 actgcaatca tagtaagatt tgttctcata atagatagac tggacaaaac tattattacc
     3901 ccaccataat ctatcggaac atcagctaaa actattatta aacctattat tccaaacaat
     3961 aatccttgaa taaaagttaa aaaaacaaat ttattctgat actcattaga atgattcctt
     4021 ttaaaggtcg agtaagcctg acctaaacca actccaccta aaatataaaa aatttctact
     4081 aagttcatta cataggcata atctcctttt ttttcaacac ctaatcccct attaattata
     4141 attgaggata aaagtgttaa taagattaac aaaaatttac tcgttaaagc aaaccaatat
     4201 ttcttagata gtctcactta ttttctccgt atgttaaatt ttataacagt aaatttaaaa
     4261 ttatagtata ttgaaataga atatgaacaa aacgattagg gaatttaaag taatttataa
     4321 aaattcttta gaagctgcat tgtactactc caacttcaaa ccactatagt atcaaaaagt
     4381 ataccccacc tttttaaata aactactcac cacccatttc atccaatggt gatatcaaca
     4441 ccattctatt gataaaaaca ataaccaatg ttcccaatat agcatattta agtaatggag
     4501 ataatatgtt agcaaaatca gcacgagtag aataaataaa aataggtatc atatacagat
     4561 atatcagcat cccgtatata tttctttgag cgtttatata aagaaatctc atcaaaaagc
     4621 ctgttagcat aaaaatcatt acaattccaa agtatcctcc attcacatat ccctctccca
     4681 caagagtaaa accatatttg gttgaatgta cgtttggaaa aaaggtgtcc ataaaccaag
     4741 tttgattaga ataccccgta ttataaaaaa ttcttactat gtcattaaaa aaagaacgac
     4801 cttcgaaata attgcccata ttatgtaata tcagaatctg taaattacga ctagctgata
     4861 caaactcacc atctagcaaa tcaaaccaaa tattatttgt atttatagat gaaacttgcc
     4921 cacttaataa agtatattta aaaactgcag ataacggaat cagtagtgcc gcaagcggaa
     4981 ctaacattac aagataaaaa cgttttattt tgtgaaagta aaataatata atcacatcaa
     5041 ggatgaataa agtaaacata taatctcttt cccctgtaac gatagagaag agacagataa
     5101 ctatcgctgt gttagtatta caatttagta gtctccattt tttagtactc aactgtataa
     5161 atagctgata tgtatgaatg agaatcataa aataaaccaa agaaaatact aacattatca
     5221 caatattggc acctgaatat atttcccctt tatttctaaa accacttcct aatagatata
     5281 taattgctac tgttgtgata aacgtattca tattattgag aaataataaa tagttattgt
     5341 tatttaggtt tattttcctt tcgcttaaca caatggcttt agaaggtaga gttaacaaca
     5401 aagttgccaa agccagccat tgcatgaaaa tcaaatcttt tgtataacca tagtttatat
     5461 actccattct atagagtagc gggtaagaaa tagaataaat agtaaagaag ctactatacc
     5521 acacataggg atgaaaaata ttaaatttca caattatcat tgccataaaa cttaaaaaaa
     5581 tcattgaaaa taatggaatt gtaacatcat tattttcact gcataaaatt aaagtccctg
     5641 aaaaaactac acctactaga agtattattt tattttttat atcatttgat tgtagactaa
     5701 acttcattta cttttttcct ttaactaata atttaaacgt aatgcgtatt caaaaatttg
     5761 attggctatg tagtcagttt ttatagcata tttaatatat cgaaacggat tttccatcgc
     5821 attttaatct aaaccatcag aattatttaa ttctcttcta atttgagcaa aatagtcact
     5881 tctgcgttta tttaatacac tcgaaagaaa tttttttgag aattcaaact gttttatcac
     5941 catcttttcc ttatccatac taataaaatc tataatagat cccgcaatcg cttgtgaaga
     6001 ggatggagta aatagacaat gtggccccag caactctgga attcctgctt tattagaccc
     6061 tatacaaggg caagcacggc tcatagcttc aattaccgca cgaggtaacc cttcttgtaa
     6121 acttggttgt atatataaat caactttatc caaatactca taaatttgtg atgtagtcaa
     6181 ttcccctaaa aaatggattc tattcgctac tcccaattcc tctgctttct tttttaagaa
     6241 actttgatca ccatcacctg ctaaataata atccaacaaa ataccttgta tttctaatct
     6301 cttcattgct tccaatacaa atctatggcc cttggctcgt acattcacag atgctgttgt
     6361 cattattgaa attttttgag gattaaattt tttcaactta taaagacggc tcttcaaaga
     6421 tctattctct acagaggtaa tattaacatt tgaagcaacg atattagatt taatattagg
     6481 atatctatct tgtaaatatt tttctgtcac gtatatgcaa taattagcgt tttttacaat
     6541 tgatttagtt ttggcgtata tatatggagc taataatttt ccctttaaac tatgatacca
     6601 gtaagaatcc caagcatccc ccattatttc tgtcagatac ggcttaccta tcttcaatgc
     6661 gtagtctgca gtttttgatc caattataga cggaatacga acaactatta agtcgctatc
     6721 aatcattcct tcaataatct tatttttatt ttgaccaaat agaacctgat gtagaccttc
     6781 tatagggata aatttattaa taaagttcgc tttatgatat ccttcagggt atgattccac
     6841 cttctcataa cgactacata gtacaatctc tccaaatgct ttagcatagc gctcataaat
     6901 aaaataagct ttcggtttta aatatatttc atttttatag attgtacatc taaattcagt
     6961 cgctataaat actttcataa tttcatctcc cttgataaac gtttctgaat aaatatagta
     7021 tcagctggaa tatcctttgt tacaacactt cctgctgcaa ccacactatt ctcaccaata
     7081 ctcactccct tcaagacaat gctgttagct ccaatccaaa cattttctcc aatcataact
     7141 ggggccgtct taaatttttt tgctttcaat ccacctggaa cactaacatc atagtcatga
     7201 tcatatataa gtactccagg accacatttt actccagatt taatatctat gtatttacga
     7261 caagctatca tacaattatt actcaaaaat acatcatcag aaatcttgag ttttgctcct
     7321 tttctaactt tcaatactcc cccggcgttt actctaatct tttttcctaa gattaattta
     7381 gcattagatt cctgttcgac agttacattc tttccaaatt ttaaaaaata atgaaaagta
     7441 agatccttgt ttcgacacac ttttaataat atcaagcaaa tatttgcacg aagtaaacca
     7501 acaatatttt ttataatcct attcatctaa agctcctttt attttatcta aataagcatc
     7561 tataataatt tgacgagaaa aatattgctc tatatacatt ctcccttgaa gtcccatctc
     7621 ttttcgtttt tcattttcta gacctaaaaa aacttccaat atagagacta gttcctcaac
     7681 atttccccct tgaaatatat agcctgtctc tctatcttta acaatttctt tgcaacctgg
     7741 attatctgtc gtaattaaaa cacgtcctga actagcgttt tctagtaata cattgctcat
     7801 tccttcacca tacacactgg gatggataat tgcatgggaa cgggtaatat gaggtatcac
     7861 atctttttgt tgtcccaaat aataaacgat tccttttttt tctaagtcac aaattttaag
     7921 ttcataatta ctctctgtcg gttctataaa gccaataata ttaaactctg ttttgggata
     7981 tcgactctta ataatttggg cagcagccag ataagtatct ataccttttt cttttaatat
     8041 cctaccaata aaattaaaaa cgattgtttc tccttgaatt ccatttccac catttggata
     8101 ctgttgcaca ggatactttt caatgttcac tcctgaccca ggtatcagct tagagtcacc
     8161 caaaatcaag ccaagagttt ttaacatttt catattatat tcattttgaa aaaaaacaca
     8221 atttgatttc ctaaaagaaa ttctaaacag taataacacc aggcttctta cacaagaacc
     8281 cattgttaag acactaccta aacctgttac gttatttata tattttattc ctaaaattgt
     8341 tgcagctagg ctagcatata catttggttt cacggtatat gtcaagacta catccggtct
     8401 atattttctc aataatctta tataactaag aaatagacga atatctttta aagggtttat
     8461 tcctcttcta tcaatagtaa tatcttcata ctcaaattga atagacttca tcaactctat
     8521 cttatctcca taaggacatg acactagcac ttcataccca tactcaacta gtgactctat
     8581 aacttctttt cgaaaacaat agatatcatc gtcatgatta gttattaaca taattttttt
     8641 cttttgtaaa ttcatcaaaa taatcttcct aaaatataat taaccgctac tccattatcc
     8701 tttacaacta tcattttaaa aatagtaatt ttctataagt aattgtttcc aaattgtgac
     8761 actttaaaat tctatacaca tatagaactt acaaactatt tacgaccgta aactccatac
     8821 ttatcaaccg agatatccaa tttatttaaa acaactccca ggaacagttt ccctgtttgt
     8881 tctaattgtt gtttcgcttt ttggacatca cgtttattcg cctcacctgt tgctgttatc
     8941 aagatggacg catcacactt ttgagtgata attgccgcat caataacaat tccaataggt
     9001 ggtgtatcaa caatgatata atcaaaatat ttacgcaatg tttcaatcat atcattaaaa
     9061 tttttacttt gtaacaaggc tgtagggttt ggtgatacag atcccgattg aactacaaat
     9121 aaattttcaa tatttgtatc acataaaccg tgagataaat cagctgtccc agataaaaat
     9181 tctgttagcc ctgtaatttt ttcacgagat ttaaaaaatc ctgacataac tgaatttcga
     9241 atatcgccat cgaacaaaag agttttatag cctgcacgcg caaatgacat tgctatattt
     9301 acggaagtag ttgtttttcc ttcccccgga ttaacagaag taacggaaat tacttttagt
     9361 ttatctccgc tcaactgtat atttgtacac aaggtattgt aatattcttc tgccttctta
     9421 atgaactcca gttttttttg tgctatttct aatgtcggca tctctctctc ctatttcaac
     9481 ttacccaagt ttggtacaac tcccaaaagt gtcatctgca gtgcattttc gatatcttcc
     9541 ggacgtttca cacgagtgtc caaaagttca agaagaagaa ctataacact agttccaatc
     9601 acccctgcca aaaaaccaat tagtgtattg cgtttaatat ttggcgaaga cggtgatatc
     9661 gccggtcttg cctcctccag tgttgtcaca tcagaaacac gagtaatact gataattttt
     9721 tgagcagcta cttctcttaa agagttagcg atacggcttg cctcttcagg aactcgatca
     9781 ctaactgaaa cagagacaat acgggtatca actggtactg ttactttaat tttattagcc
     9841 aaaccttttg gcatcaaatc tagtttcaaa tcagaaataa cttcctccaa aacatcctgc
     9901 gataggacaa tttcacgata gtctttaacc aagtatgctc ctgcctgcaa gtcttgattg
     9961 gttaaaccag gcttctctcc ctgattacgg ttaactacat aaatccgagt cgtactagta
    10021 aactcaggtt tgataacaaa agtactgtag gcaaaagcaa ctgaagaagt tataattgcc
    10081 actaataaaa tgaccaactt tcttttccat aaagctctga atagttgcaa tacatcgatt
    10141 tccaaagtgt tttgttcctt catattttct cctaaattaa ttgatccatt ataatttttc
    10201 tgggattatc tacaaaaagt tctttcgctt ttttcgctcc atatttctta gcaatgatat
    10261 catatgcctg ttgcatatat ggaggtctac tgtctaaatt gtgcatgtca cttgcaacta
    10321 catgaactaa atcacgttcc aaaaaatacc gagctctctt tttcatgaat ttatattttt
    10381 caccaaagaa cttaggtttt gaaacatgat aactatttat ctgagtatag caccccatat
    10441 caatcagttc acgaacacgt ttttcgttat tctctaaagc atcataacgt tcaatatgag
    10501 caattactgg cgtgattccc aacatcaaaa tattgctcaa tcccgtatga atctgacgat
    10561 aggaagtatg catgctaaac tcaatcaagg cataacgact atcattaagg gtaggaattt
    10621 cttttttttc tagcttttct agagcatcca gagtatagta tatctctgcg ccataagcaa
    10681 tgactaaatc atctgctact tcttttgcaa tttcccgaac ctgaagaaag ttttctgcta
    10741 tcttctcttc cggagtttca aacatgccct tgcgacggtg agaggtagag acaatggttc
    10801 tcaccccctg cctgtaggat tctgccaaga gagccttgct ttcctctctt gacttgggac
    10861 catcatctac atcaaagacg atgtgcgaat ggatgtctat cattttatct accctccatc
    10921 acatcctgta tagctgcttt aactacagtt aaactactat catctatttc catcacatag
    10981 aggttactgt ctggcattgc ataagaagga agatccatcc gacctgtccc ttttaaatct
    11041 tgagaattta ctttataatt ccctccactt tccaactgag tattcactaa atctatcata
    11101 gtctcaatcg gtatatttgt ttgaagagaa tcctgcaatc cttgaagaat actactatag
    11161 tttttcaaaa cctctgtaga agttaacttc tgaataattg ctacaatgac cttttgttgg
    11221 ttgcgaccac ggtcacggtc tccatcggtt agtgagtagc gttcacgtac aaaacctaaa
    11281 gcttgctcag agtctagatg gacattccct actgggaaat ggaacttccc atgtagagct
    11341 gaaaactctt gatcattatg aacatctacc cctcccaata agtcaatcat tttcaagaaa
    11401 gaagtgaagt tcaatcgcac atagtaattg atatccactc catagagatt ttctaaggtg
    11461 tgaatggacg aatcaactcc ataaatgccc gcatgggtta atttatcttt ttgattattt
    11521 ccactatctg cgattggtac ataggcatca cgtggcgttg tggtcaagag gattttcttg
    11581 gtatctcgat tgacagtcat taggatattg acatctgatc gcgacaccga actaatagga
    11641 ccataggtgt caattccact aacatagata ttgaaagact gattcttaga cgtcttagga
    11701 gcctctactt ttttagtgaa tcccttggta taaatctttt ttatcttcga tgcgtagtct
    11761 ggatactctg actcgatgat attttcaaag acactattta ggacaatggc cttagtctcc
    11821 cctgcaatca aactcttgta agctgccaag taagacgaac tctggttgac cgtcaaatcg
    11881 gtattctgac ttgacttgat atcagctagt agtttttgaa tattttcatt atcagtccca
    11941 gtcggtgctg tcacactcgt cagttgcgta acattttcga tcttactatc tgctaaaaca
    12001 gcgacactga ttgaatattc tgagtaatta gaagtcgcat ttaaacgatt ggtcagtcca
    12061 acaaactgct gtactgcaaa gagcgacact gagctgacaa ggatagagaa cagcaacaga
    12121 aaaatagtaa acttttcagc ttttttatag ataatcaaga gtagccctac caaggcaact
    12181 agtaggacta acgcagttac cactaggtta agatatctaa aagcaaggat attgtactta
    12241 aagattaaga acaataaaaa acaaattaac aataaataaa tagtcagcaa aacgatatta
    12301 acacttcgct tcactttctg tgaacgtgat tttttaaaac gtctactcat gattaacacc
    12361 tataccttga acatcataca attatatcac ttttttacgg taatgtctac acctttattt
    12421 tcactatctg catctttaag tatcttagta gacttcccgc gaaccaaaaa tatagtaaaa
    12481 tgaaataaga ataggacaaa tcaatcagga cagtcaaatc gatttctaac aatgttttag
    12541 aatcagatgt gtactattct agtttcaata taa
//
LOCUS       DAVBOD010000057        12104 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 640-05
            SAMEA1012484-rid20186543.denovo.057, whole genome shotgun sequence.
ACCESSION   DAVBOD010000057 DAVBOD010000000
VERSION     DAVBOD010000057.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012484
            Sequence Read Archive: ERR059358
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12104)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12104)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979948.1
            Genome Coverage       :: 595x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:03:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,266
            CDSs (total)                      :: 2,219
            Genes (coding)                    :: 2,091
            CDSs (with protein)               :: 2,091
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 71 of 128
            Pseudo Genes (incomplete)         :: 50 of 128
            Pseudo Genes (internal stop)      :: 33 of 128
            Pseudo Genes (multiple problems)  :: 22 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12104
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012484-rid20186543.denovo.057"
                     /strain="NIG 640-05"
                     /db_xref="taxon:1313"
     gene            complement(82..252)
                     /locus_tag="VQ862_001742"
                     /pseudo
     CDS             complement(82..252)
                     /locus_tag="VQ862_001742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040325.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
     gene            complement(560..994)
                     /locus_tag="VQ862_001743"
                     /pseudo
     CDS             complement(560..994)
                     /locus_tag="VQ862_001743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001817843.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(1131..2015)
                     /locus_tag="VQ862_001744"
     CDS             complement(1131..2015)
                     /locus_tag="VQ862_001744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PucR family transcriptional regulator"
                     /protein_id="HET3116048.1"
                     /translation="MREKELQDWFPEARISDQPVEKEGYLTLPLASQQWILLEEAGLS
                     EREKQLVALLTQQEQARSLNPWYSYLVEGKGQAPQVFKKIQLVYCHLSYFQQENLASW
                     LDMMRTLFPNCQTVLQVGSQDYVFVLQQDKYTYVRDILSDTIEAVEYDFGLRLSIMLG
                     QVWSQTGHQALSDLIKAERDLFKTWWRQGHQGVHTFSQLYLWSMGERLVDLKPIKECL
                     HQMILDQDQIQEIILSLWENSAVLTKTAQQLYLHRNSLQYKIDKWEELTGLQLKELTD
                     LTLCYQLILGSLSTIVGL"
     gene            complement(2019..2405)
                     /locus_tag="VQ862_001745"
     CDS             complement(2019..2405)
                     /locus_tag="VQ862_001745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006148900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mini-ribonuclease 3"
                     /protein_id="HET3116049.1"
                     /translation="MIDVNLINGIALAFEGDAVYSMYIRRHLILKGMTKPNKLHQEAT
                     KYVSAKAQARLIALMLEEQVLTEKEEEIYKRGRNTNSHTKAKNADVVTYRMSTGFEAV
                     MGYLHMTENLERLESLVSWCIQKVEG"
     gene            complement(2398..3741)
                     /locus_tag="VQ862_001746"
     CDS             complement(2398..3741)
                     /locus_tag="VQ862_001746"
                     /EC_number="6.1.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002916477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine--tRNA ligase"
                     /protein_id="HET3116050.1"
                     /translation="MIKIYDTMSRDLREFVPIEDGKIKMYVCGPTVYNYIHVGNARST
                     VAFDTIRRYFEYRGYKVAYISNFTDVDDKIINRAREEGITPQEVADKYIAAFREDVTA
                     LGVKPATRHPRVVEFMADIIRFVEDLIEKGFAYESQGDVYFRVEKSHNYAKLANKTLE
                     DLELGASGRTDEETARKENPVDFALWKSSKPGEISWDSPWGPGRPGWHIECSVMSTEI
                     LGDTIDIHGGGADLEFPHHTNEIAQSEAKTGKAFANYWMHNGFVNIDNVKMSKSLGNF
                     ITVHDALKTLDGQVLRFFFATQHYRKPINFTEKAVRDAETNLKYLKNTYEQPFTGNVD
                     AQELQNFKDKFVAAMDEDFNAANGITVVFEMAKWINSGNYDASVKQALADMLEIFGIV
                     FVEEVLDAEIEDLIQKRQEARANRDFETADQIRDQLVTQGIKLLDTKDGVRWTRD"
     gene            complement(3823..4707)
                     /locus_tag="VQ862_001747"
     CDS             complement(3823..4707)
                     /locus_tag="VQ862_001747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000613615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET3116051.1"
                     /translation="MIQARNKLSQEELSEAKKVINCCQNYDGTYRDPYLSNMLNFDPN
                     MPAFFLYYEKGELVGLLTVYADDQDVEVTILVHPGHRRQGIARALFTSFEREIASFPI
                     RSVTFQTERIFLENHPDFASNWGLIEDEETETWLGKDRRPYPLANVSHLEVLLADSSY
                     QDQISQLKFQAFSEEHESREVVDRYVAEALKDPESRLYILLKDGQVIGTCTVDLSTNT
                     NYFYGLAILEPERGKGYGSYLAKSLVNQLIEQNDKEFQIAVEDSNVGAKRLYEKIGFV
                     KQTQVVYLNEKGARDSEV"
     gene            complement(4719..5336)
                     /gene="cysE"
                     /locus_tag="VQ862_001748"
     CDS             complement(4719..5336)
                     /gene="cysE"
                     /locus_tag="VQ862_001748"
                     /EC_number="2.3.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000539958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine O-acetyltransferase"
                     /protein_id="HET3116052.1"
                     /translation="MGWWRETIDIVKENDPAARTTLEVLLTYPGVKALAAHRLSHFLW
                     KHGFKLLARMYSQFWRFWTQIEIHPGAQIDSGVFIDHGSGLVIGETAIVEKGVLLYHG
                     VTLGGTGKDCGKRHPTVRKGALISAHAQVIGPVEIGENAKVGAAAVVVADVPSDVTVV
                     GIPAKIVRLHGKKDEPVIHEVEEKREYYVNKLEQAKDASHRSSGL"
     gene            complement(5352..7565)
                     /gene="pnp"
                     /locus_tag="VQ862_001749"
     CDS             complement(5352..7565)
                     /gene="pnp"
                     /locus_tag="VQ862_001749"
                     /EC_number="2.7.7.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001854499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyribonucleotide nucleotidyltransferase"
                     /protein_id="HET3116053.1"
                     /translation="MAKQVFQTTFAGRELIVETGQVAKQANGSVVVRYGESTVLTAAV
                     MSKKMATGDFFPLQVNYEEKMYAAGKFPGGFMKREGRPSTDATLTARLIDRPIRPMFA
                     EGFRNEVQVINTVLSYDENASAPMAAMFGSSLALSISDIPFDGPIAGVQVGYVDGQII
                     INPSQEQAEQSLLELTVAGTKHAINMVESGAKELSEEIMLEALLKGHEAVKELITFQE
                     EIVAAVGKEKAEVELLHVDAELQAEIIAAYNSDLQKAVQVEEKLAREAATQAVKDQVT
                     AVYEEKYANHEEFDRIMRDVAEILEQMEHAEVRRLITEDKVRPDGRKVDEIRPLDAVV
                     DFLPRVHGSGLFTRGQTQALSVLTLAPMGETQIIDGLDPEYKKRFMHHYNFPQYSVGE
                     TGRYGAPGRREIGHGALGERALAQVLPSLEEFPYAIRLVAEVLESNGSSSQASICAGT
                     LALMAGGVPIKAPVAGIAMGLISDGNNYTVLTDIQGLEDHFGDMDFKVAGTRDGITAL
                     QMDIKIQGITAEILTEALAQAKKARFEILDVIEATIPEVRPELAPTAPKIDTIKIDVD
                     KIKIVIGKGGETIDKIIAETGVKIDIDEEGNVSIYSSDQDAINRAKEIIAGLVREAKV
                     DEVYRAKVVRIEKFGAFVNLFDKTDALVHISEMAWTRTNRVEDLVEIGDEVDVKVIKI
                     DEKGRIDASMKALLPRPPKPEHDEKGEKSERPHRPRHQKDHKPKKEFTETPKDSE"
     gene            complement(8124..8990)
                     /gene="metF"
                     /locus_tag="VQ862_001750"
     CDS             complement(8124..8990)
                     /gene="metF"
                     /locus_tag="VQ862_001750"
                     /EC_number="1.5.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000089969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate reductase [NAD(P)H]"
                     /protein_id="HET3116054.1"
                     /translation="MSRQTPSLSFEVFPPNPAVGNGNIISALQDMQELAPHFISVTAS
                     NNKFNIKETTVRLADFIQNDLAIPTIAHLPAIYLTKDKVAETIVDLDKVGVQKILALR
                     GDIIPDVEPQKDFRYATDLIEFIKEQAPHFDIIGACYPEEHPDSPNQISDIQNLKKKV
                     DAGCSSLVTQLFFDNERFYDFQDKCILAGIDVPIHAGIMPILNRNQALRLLKTCENIH
                     LPRKFKAILDKYEHDPESLRAAGLAYAVDQIVDLVTQDVAGVHLYTMNNADTAKYIHQ
                     ATHALFNHQSLG"
     gene            complement(9054..11303)
                     /gene="metE"
                     /locus_tag="VQ862_001751"
     CDS             complement(9054..11303)
                     /gene="metE"
                     /locus_tag="VQ862_001751"
                     /EC_number="2.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-methyltetrahydropteroyltriglutamate--
                     homocysteine S-methyltransferase"
                     /protein_id="HET3116055.1"
                     /translation="MSTTIIGFPRLGEFRELKFTTEKYFRKEISEEELLAAAKDLRAK
                     HWNIVKEKGITEIPSNDFSHYDNFLDAAFLFNVVPASVQNLGLSDLERYFALGRGYQG
                     EKGDVRALPMKKWFNTNYHYIVPKFEKDTQVKLAGHKIFDEFQEAKELGLNTRPVLVG
                     PFTFLQLSDFEEGVKADDFVDSLVAAYQEVFAKLAELGATRIQLDEAALVKDLTAEEK
                     ALFLNLYNKLLADKKGLEVLLQTYFGDVRDVYADLVNLPVDAIGLDFVEGKKTLELVK
                     GGFPADKTLYVGIVNGKNIWRNNYEKSLAVLEQIPAENIVLTSSCSLLHVPFTTANEE
                     FEPALLNHFAFAVEKLDEIRDLDAIRNGQGSEALAANKELFATERVGENAELRARIAG
                     LTDADYTRLPAFAEREAIQEEAFKLPALPTTTIGSFPQTKEVRAKRLAYRKGELSQKE
                     YDAFLAETIDEWIKWQEDIDFDVLVHGEFERNDMVEYFGQNLSGYFFSKNGWVQSYGM
                     RGVKPPIIWGDVTRLNPITVKWSSYAQSRTNKPVKGMLTGPVTILNWSFPREDISIKD
                     STLQIALAIKDEVLDLEAAGVKIIQIDEAALREKLPLRRSDWYEDYLDWAIPAFRLVH
                     STVASDTQIHTHMCYSEFTDIIPAIDNMDADVISFEASRSNLEILDELKAKNFQTEVG
                     PGVYDIHSPRVPNEGEIDNTIEAILAKVPSKKVWINPDCGLKTRGIPETKESLIRLVE
                     AAKAAREKL"
     gene            complement(11563..11829)
                     /locus_tag="VQ862_001752"
     CDS             complement(11563..11829)
                     /locus_tag="VQ862_001752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET3116056.1"
                     /translation="MEGCPSELFSKEEILESDMRVAIMSELIEARNKQGISQKKLEEL
                     SGVSQPVIARMETGKTSPQLDTVLKVLASLGKILAVVRLEQGKS"
     gene            complement(11955..12104)
                     /locus_tag="VQ862_001753"
                     /pseudo
     CDS             complement(11955..12104)
                     /locus_tag="VQ862_001753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155321.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
BASE COUNT         3388 a         2740 c         2329 g         3647 t
ORIGIN      
        1 tatacctcta cttctaaaat attgttagaa atcgatttga cttccctgat cgattcgtcc
       61 tattcttatt tcattttaat ataattgata gtgctcgccc cagccagata ccttatctgc
      121 tatccattta ggaaccccta acttaagcaa tccccataat cgtctcgatt tcttcttcca
      181 ttgcttccag ataatcactc gtaggcgagt acgcaagcgc tcatctatgt tagtgactat
      241 acttttcata tttataattc attcctttcg tttcactcaa ggcacaacac agaatgaaaa
      301 agtgttgtga tctttatttt gttttataat aatagtgaga aagcctatca ctactacaaa
      361 tcacggggag gtgaataagt gagtggtaca gccactacct cgcatatttt gtcacatcat
      421 ttaacggtac ataataagtt gtaccatctg aataagttgc tacaatatca tttgcatgct
      481 ctccttcacc tttagcaaag gttggagctc ctgctggatg atttttattt gcctctttca
      541 atttttcaat aatggcattt ttttctgtat cttttatatt atcaggattt ttcactaaaa
      601 ttttgtctgg atatgtcggt ttagcagaaa caatttttac tgttacttct tttttattcg
      661 aagcacttgt ccagtttcca gcattatctt tagcatttaa ttttacagta attcctgaac
      721 taggaacttc agtagcaggt tgattatcaa cattattcaa ctttaatttc aaaagagctg
      781 ttgcatcaga cgttttatca atcgttatat ataatgatga attgttatta taaccagttc
      841 cttcatattt agctgtttgt gagctacttg aaacagaact gaaattatac ccactacctc
      901 cctgattatc ttcaatgctt acgtctaaat aaacttcccc actattattt agcttagcaa
      961 caactgttat agtaaaataa cataaaattc acataaatag attagggaaa tcaaagcaac
     1021 ttctaggaat gttttagcag tcacagtgta ctttcccagc atcaagccac tataactctg
     1081 cacataaaaa tggagaagat ggccatcctc ttctccaaat attaacttct ttacaaacca
     1141 actatagttg acaaagaacc taaaatcaat tgataacaca aggtcaggtc ggtcaactct
     1201 ttcaactgaa gccctgtcaa ctcttcccat ttatcaatct tgtattggag agaattgcgg
     1261 tgcagataga gttgctgggc tgttttagtg agaacagcac tattttccca aagagagaga
     1321 atgatttcct gaatctgatc ttgatccaaa atcatctggt gtagacattc cttgattggc
     1381 ttcaagtcca cgagtctttc tcccatactc caaagataga gctgagaaaa agtatgaaca
     1441 ccttggtgac cctgacgcca ccatgtcttg aacaaatccc gctcagcttt gattaagtct
     1501 gatagggctt gatgtcccgt ctgagaccaa acctgaccca acatgataga aagacgaagt
     1561 ccaaagtcat actcaaccgc ttcaatcgta tcacttaaaa tatctcttac ataagtgtat
     1621 ttgtcttgtt gaagcacgaa aacataatcc tgagatccga cctgtagcac tgtctgacaa
     1681 ttcggaaaaa gagtccgcat catatctagc caagaagcca gattttcctg ctgaaaataa
     1741 gaaagatggc aataaaccaa ctgaatcttt ttaaaaactt gcggtgcctg tcccttgcct
     1801 tcaaccagat aggaatacca agggtttagc gaacgagcct gctcctgctg ggtcaaaagg
     1861 gcaaccaact gcttttcacg ctcgctgagc ccagcttcct ccagcaaaat ccactgctga
     1921 gaagctaaag ggagcgtgag atagccctct ttctctactg gttggtctga aatccgagcc
     1981 tcaggaaacc agtcttgtag ttctttttcc ctcatgttct agccctccac tttttggatg
     2041 caccatgaaa ccaaactctc aagacgttcc agattctcag tcatatggag atagcccata
     2101 accgcttcaa atcccgtgga catacgataa gtcacgacat ctgcattttt agcctttgtg
     2161 tggctattgg tattgcggcc acgtttgtag atttcttctt ctttttccgt taggacctgc
     2221 tcctccaaca tgagagcaat caggcgagcc tgagccttgg ctgacacata cttggttgct
     2281 tcttgatgga gtttattggg tttggtcata cctttgagga tgaggtgacg gcgaatatac
     2341 atagaataca ccgcatcccc ctcaaaggct agcgcaatcc cgttaatgag attgacatca
     2401 atcacgtgtc cacctcactc catccttggt atcaaggagc ttaattcctt gagtaaccaa
     2461 ttggtcacgg atttggtctg ctgtctcaaa gtctcgattg gcacgcgcct cttggcgttt
     2521 ttgaatcaag tcttcaatct ctgcatccaa aacttcctca acaaagacaa ttccaaaaat
     2581 ttctaacata tctgcaagag cttgcttgac acttgcatca tagttccctg agttgatcca
     2641 tttggccatt tcaaagacaa ctgtgatacc gttggcagca ttaaaatctt catccatagc
     2701 tgctacaaac ttatctttaa agttttgtaa ctcttgggca tccacgtttc ctgtaaatgg
     2761 ttgttcgtaa gtattcttca gatacttgag attggtctcg gcatcgcgaa ctgccttttc
     2821 cgtgaagttg ataggcttac ggtagtgctg ggtcgcaaag aagaaacgaa gtacttgccc
     2881 atcaagagtt ttaagggcat cgtgtaccgt aatgaagtta cccaaggact tagacatttt
     2941 gacattgtcg atattgacaa agccattgtg catccagtag ttagcaaaag ccttgcctgt
     3001 tttagcttca gattgggcaa tttcattggt gtggtgtgga aactctaggt cagctccacc
     3061 accgtggata tcaatggtat cacctaaaat ctctgtcgac atgactgaac actcaatatg
     3121 ccaacccgga cgtccaggtc cccaaggact atcccaagaa atctcacctg gtttggaaga
     3181 tttccataga gcaaagtcta caggattttc cttacgagcc gtttcttcat cggtacgacc
     3241 tgaagcacct agctccaaat cttccaaggt tttattagcc aatttagcat agttgtggga
     3301 tttttctaca cggaaataga catccccttg actctcatag gcaaagcctt tctcgatcaa
     3361 gtcttccaca aaacggatga tgtctgccat aaactccact acacgcggat ggcgagtcgc
     3421 aggtttcacg cccaaggccg tcacatcctc acgaaaggca gcgatgtact tatccgcaac
     3481 ctcctgaggc gtgatgcctt cttccctggc acggttgata atcttatcat ccacatctgt
     3541 aaaattggaa atataggcaa ccttataccc acggtactca aaatagcgac gaatcgtatc
     3601 aaaagctacc gtcgaacggg cgtttcccac gtggatatag ttgtacaccg ttggcccaca
     3661 aacatacatc ttgatcttgc cgtcctcaat cgggacaaat tctcgcaaat cacgagacat
     3721 ggtgtcatag attttaatca taaatcataa tcaggaaagc tgaaatccaa gaacaattag
     3781 tttcatcact aaaagttcaa gtaaatttca gtccgaatat ctctacactt cggaatccct
     3841 tgctcctttc tcattcagat aaaccacctg agtctgtttg acaaagccaa ttttttcata
     3901 caaacgtttg gcacctacat tgctatcttc cactgcaatc tgaaattcct tgtcattttg
     3961 ctcaattagt tggttgacga gggattttgc taagtagctt ccatagcctt ttccacgttc
     4021 aggttccaat attgctaaac cgtagaagta attcgtatta gtcgataaat caaccgtaca
     4081 agtcccaata acctgaccgt cttttaataa aatatataag cgactttctg gatccttcag
     4141 agcttcagcg acatatctat ccacaacttc tctcgattca tgttcctctg aaaatgcctg
     4201 aaattttaat tgactaattt gatcctgata cgaactatct gctaacaaaa cttcaagatg
     4261 ggaaacattt gctaacggat aaggtcttct atccttacct aaccaagttt ctgtctcttc
     4321 atcctcgatt agtccccagt tactggcaaa gtcaggatga ttctctaaaa aaatacgttc
     4381 tgtctgaaaa gtgactgacc gaatggggaa agaagctatt tctctctcaa aactagtaaa
     4441 caatgcacgc gcaatcccct gacggcgatg acctggatga accagtatcg ttacttctac
     4501 atcttggtca tctgcataga cagttaataa accaacaagt tcgccttttt cataataaag
     4561 gaaaaaggcg ggcatgtttg ggtcaaaatt aagcatgtta gagagatagg gatcgcgata
     4621 ggtaccgtca tagttttggc aacagttaat tacttttttc gcttcagata gctcctcttg
     4681 gcttaacttg tttcttgctt gaatcatata ggtatcctct acaaaccaga cgatctgtga
     4741 ctggcatctt tagcctgctc gagtttattg acataatact ctcgtttttc ttcgacttcg
     4801 tgaatgacag gctcatcttt cttaccatga agacggacaa tcttggccgg aataccgaca
     4861 accgtcacgt cactaggtac atctgctacg acaactgctg cagcaccgac cttggcattt
     4921 tcaccaattt ccacaggccc gataacttgg gcatgggctg atatgagggc tccctttcgt
     4981 acagtcggat ggcgtttgcc acagtctttc cctgttcccc cgagagtcac tccgtgatag
     5041 agaagaacgc ctttttcaac aatcgctgtc tctccaatca ccagaccaga accatggtca
     5101 ataaaaacac ctgaatcaat ctgggctcct ggatgaatct caatctgagt ccaaaagcgc
     5161 caaaactgac tgtacatacg agctaatagt ttgaagccgt gcttccagag aaaatgcgag
     5221 agacggtggg ccgccaaggc cttgacacct ggataagtca gcaaaacctc caaagtggtg
     5281 cgggccgctg gatcattttc ttttacaata tcaatggttt cgcgccacca ccccatacat
     5341 ttctcctttt cttattctga atcttttggt gtttctgtaa attctttctt aggtttgtga
     5401 tccttttgat gacgtgggcg gtgagggcgc tcagactttt cacctttttc atcatgctca
     5461 ggttttggcg gacgaggtag aagagccttc atagaggcat cgatacggcc tttttcatca
     5521 atcttgataa ccttaacatc aacttcatcc ccgatttcta ccaaatcctc tacacgattg
     5581 gtacgagtcc aagccatctc agagatatga acaagggcat ctgtcttatc aaagaggtta
     5641 acaaaggcac caaatttctc gatacgaacg actttagcac ggtaaacttc atccactttg
     5701 gcttcacgaa ccaaaccagc aataatttct ttggcacggt taatagcatc ttggtcacta
     5761 gagtagatag acacatttcc ttcttcgtct atatcaatct taacacctgt ttcagcgata
     5821 atcttgtcga tggtttctcc acccttaccg atgacaatct taatcttgtc cacatcaatc
     5881 ttgatcgtat caattttcgg agcagttgga gccaattctg gacgaacttc tggaatggtt
     5941 gcttcaatga catcaaggat ttcaaaacgc gctttcttgg cttgagcaag agcctccgtc
     6001 aagatttctg cagtaatccc ttgaatcttg atatccattt gaagggctgt aatcccatca
     6061 cgagtacctg caaccttgaa gtccatatct ccaaagtgat cttccaaacc ttggatatct
     6121 gtcaatactg tgtagttatt tccatctgag ataagtccca tagcaatacc agctactggc
     6181 gccttgattg gcacaccacc agccataagg gcaagagttc ccgcacagat agaagcttga
     6241 gatgaagaac cgtttgattc caaaacttct gctactagac ggatagcgta tgggaattct
     6301 tccaagcttg gcaagacttg agcaagagca cgctcaccaa gagcaccgtg accgatttca
     6361 cgacgacctg gcgcaccgta acgacctgtt tcccctacag aatattgagg gaagttatag
     6421 tggtgcataa agcgtttctt gtactctgga tccaaaccat caatgatttg agtttctccc
     6481 atcggagcca aggtcaagac tgaaagagct tgagtttgcc cacgagtaaa gagacctgaa
     6541 ccatgtacac gaggaaggaa gtcaacaacc gcatccaaag gacggatttc atcgacctta
     6601 cgaccatcag gacgcacctt gtcttctgta attaaacgtc gcacttctgc gtgttccatt
     6661 tgttccaaga tttcagccac atcacgcata atacggtcaa attcttcgtg gttcgcatat
     6721 ttttcttcgt aaacggcagt cacttggtct ttcactgctt gagttgcagc ttcacgggcc
     6781 aatttctctt ctacttgaac tgccttttgg aggtcactgt tgtaggctgc aatgatttca
     6841 gcttgcaatt cagcatccac gtgaagcaat tccacttctg ctttttcttt accgacagca
     6901 gcaacgattt cttcttggaa ggtaatcaat tctttgacag cttcgtgccc tttaagaagc
     6961 gcttccaaca tgatttcttc tgacaattct ttggcaccag actctaccat gttgatagcg
     7021 tgcttggttc cagctactgt caattcaaga agagattgct ctgcttgttc ttgacttggg
     7081 ttgatgatga tttggccatc tacatatccc acttgtaccc cagcaattgg tccgtcaaat
     7141 ggaatatctg aaatagacag tgccaaagat gaaccaaaca tagcagccat tggtgcagat
     7201 gcattttcat cataagaaag cactgtattg atgacttgga cttcattacg gaaaccttcc
     7261 gcaaacatag gacgaatcgg acggtcaatc aaacgcgctg tcaaggtcgc atctgttgaa
     7321 ggacgtcctt cacgtttcat aaagccacca ggaaacttcc cagccgcata cattttttct
     7381 tcgtagttga cttggagtgg gaagaaatcc ccagttgcca ttttcttaga cataacggca
     7441 gcagtcaaga cagttgactc accgtaacgt acgacaacag atccatttgc ttgcttagca
     7501 acctgaccag tctctacaat taactcacga cccgcaaaag tcgtttgaaa cacttgtttt
     7561 gccattttaa tccccttttg attgatgaaa ttatacgcct tgcctacaaa gatcaagata
     7621 ccaaggacgt caaaagcaaa gtaaaaatag gaaactgacg aagtcttcga tgaagacaag
     7681 acagtttatc ttttttacac agcttttcgg ccgtgttcaa ttactcaaga taccaagccg
     7741 tcaagcaact caaaggaaga taggaaatcg aacgacggag cgactactcc tagggagatt
     7801 tatctttttc cacagagttg taggcaagtt cagttttcaa gatacatcat tagaaaggtt
     7861 taatactaaa gtatctaaag ctttcacgct aatcgctatc gggcgattag ctaaatgctt
     7921 tactaactct ctcgtcaaat aacatcgatt tgactcactc gtgtcgttaa atcttacagt
     7981 ttaaatgcat tgtattattt aataccttca tctttgtatc aagtacgtac agaatttatt
     8041 ttatcatatt tttcttaaaa agtgaggtct ttaccattaa aaaggaacca ttcccctcac
     8101 ctgagaagaa tggtttgctt ttattatcct agagactggt gattaaacaa ggcatgggtt
     8161 gcttgatgga tgtattttgc tgtatcagca ttattcatcg tatagagatg cacaccggca
     8221 acatcctgag ttaccaagtc cacgatttgg tccactgcat aggcaagtcc tgctgctctg
     8281 agcgactcag ggtcatgctc atacttgtct aagatggctt taaatttgcg tggaagatgg
     8341 atattctcac aagtcttcaa gagtcggaga gcctgatttc gattcagaat tggcataatt
     8401 cctgcatgaa tgggaacatc aatcccagcc aagatacact tgtcctgaaa atcatagaag
     8461 cgctcattgt caaagaagag ctgagttacg aggctcgaac agcctgcatc cactttcttc
     8521 ttaagatttt gaatatctga aatctgattt ggcgaatctg gatgctcttc tggatagcaa
     8581 gctccaataa tatcaaagtg aggggcttgt tccttgataa actcaatcaa gtcggttgca
     8641 tagcggaaat ccttttgtgg ttctacgtct ggaataatat ccccacgaag agccaagatt
     8701 ttctgaaccc caactttgtc caagtcaaca atagtttcag caaccttgtc cttagttaga
     8761 taaatagctg gcaagtgggc aatggtcgga atcgccaagt cattttggat aaagtcagcc
     8821 aaacgaaccg tcgtttcctt gatattaaat ttattattgc tggcagttac actgataaaa
     8881 tggggagcca actcctgcat atcctgcaag gctgaaataa tgttaccatt acccacggct
     8941 gggtttggag ggaacacttc aaatgagagt gacggtgttt ggcgtgacat atgtaataac
     9001 cttttctagt tgatttcttt ttgaacaacc actgtatgga gagaaatcca atcttacaat
     9061 ttctcacgcg cagctttagc tgcttcaaca aggcggatca agctttcttt tgtttctggg
     9121 ataccacgtg ttttcaaacc acagtcaggg ttgatccaaa ctttcttgct tggcacttta
     9181 gcaaggatgg cttcgattgt gttgtcgatt tcgccttcgt ttggtacacg aggtgagtgg
     9241 atatcgtaaa ccccaggtcc cacttctgtt tggaagtttt tcgctttgag ttcgtccaag
     9301 atttcaaggt ttgaacggct ggcttcaaag gaaataacgt ctgcatccat gttatcgata
     9361 gctgggatga tatctgtaaa ttctgagtaa cacatgtgag tgtggatttg tgtgtctgac
     9421 gctactgttg agtgtaccaa gcggaaggca ggaattgccc agtcaaggta atcttcgtac
     9481 cagtcactac gacggagtgg caatttttca cgaagagcag cctcatcaat ttggatgatt
     9541 ttcacaccag cagcttcaag gtcaagcact tcatccttga tagcaagggc gatttgaaga
     9601 gtagaatcct tgatagagat gtcttcacgt gggaatgacc agttaaggat ggtaacaggt
     9661 ccagtcaaca tacctttaac aggtttgttt gtacgacttt gtgcatagct agaccattta
     9721 acagtgatag ggttaagacg agtgacatca ccccagatga ttggtggttt taccccacgc
     9781 ataccgtatg attgtaccca tccattttta gagaagaagt atcctgacaa gttttgaccg
     9841 aagtactcaa ccatgtcatt acgctcaaat tcaccgtgaa caaggacatc aaagtcaata
     9901 tcttcttgcc acttgatcca ttcgtcaatc gtttcagcaa ggaaagcatc gtactctttt
     9961 tgagacaatt cacctttacg gtaagccaaa cgtttggcac gaacttcttt tgtttgaggg
    10021 aatgaaccaa tcgttgttgt tggaagagct ggaagtttga aagcttcttc ttggatagct
    10081 tcacgttctg caaaggctgg caaacgagtg tagtctgcgt ctgtcaagcc agcgatacgc
    10141 gcacgaagtt cagcattttc accaacacgc tcagtcgcaa agagttcttt gttggctgca
    10201 agagcttctg aaccttgacc attgcggata gcatccaagt cacggatttc atccaatttt
    10261 tcaactgcaa aggcaaagtg gttcaagagt gctggttcaa attcttcatt agcagttgta
    10321 aatggcacat gaagaagtga gcaagagctt gtcaaaacga tgttttcagc tgggatttgc
    10381 tcaagaacag ccaagctctt ttcgtagttg ttgcgccaga tgtttttacc attgacaata
    10441 cctacataga gagtcttgtc agctgggaag ccacctttaa cgagttcaag agttttctta
    10501 ccttcaacaa agtcaagacc gatagcatct actggcaagt ttacaaggtc agcgtatacg
    10561 tcacgaacat caccgaaata agtttgaagc aagacttcaa gacctttttt gtcagccaag
    10621 agtttgttgt aaaggttcaa gaagagagct ttttcttcag ctgtcaagtc ttttacaaga
    10681 gccgcttcat ccaattggat gcgagtcgca ccaagttcag ccaatttagc aaaaacttct
    10741 tggtaagcag ccactaagct atctacgaag tcgtctgctt tcacgccttc ttcaaagtct
    10801 gacaattgaa ggaaagtgaa tggacctaca agaacaggac gagtgttcaa tccaagttct
    10861 tttgcttctt ggaactcatc gaaaatcttg tgaccagcca attttacttg agtgtctttt
    10921 tcaaatttag gaacgatgta gtggtagtta gtgttgaacc atttcttcat tggaagggcg
    10981 cgaacgtccc ctttttctcc ctggtaacca cgtcccaaag cgaagtagcg ctcaaggtca
    11041 gacaagccca agttttgaac ggatgcaggc accacgttga aaaggaaagc cgcatctagg
    11101 aagttatcat agtgagaaaa gtcatttgat ggaatttcag tgatgccttt ttctttgaca
    11161 atgttccagt gtttagcacg caagtctttt gctgctgcta aaagttcttc ttctgagatt
    11221 tcttttctaa agtatttttc agttgtaaat tttaattcac ggaattcgcc caaacgaggg
    11281 aaaccgatga ttgtagttga catgatgtgt cctccaaaat ttgttgttga aactatctta
    11341 acagaaaaga aagcatctgt ataattgtaa aaaattaggc tttgatatag tttgaaacta
    11401 tacctctatt ttagacaaaa gaaaaagact tgagacacat gcctcaaatc ccttttataa
    11461 cttgttttta gctgtatttt agttagaatg ctcaaacgcg ttattagtaa ttcttataag
    11521 tgactatggc ttgttattag aaaagactat aactgattct agtcaacttt tcccctgttc
    11581 aagtcggacg actgctagta tctttcctag actagctagg acttttaaga ctgtgtccaa
    11641 ctgtggacta gtcttacctg tctccatcct agctataaca ggctgactca ctccactgag
    11701 ttcctctagc tttttctgac tgattccttg cttatttctg gcttcaatca actcgctcat
    11761 gatagctact cgcatatcac tttcaaggat ttcctccttg ctaaagagct cagatggaca
    11821 tccttccaat tactcccaat agcactattc ttcatcactt aaccctcttt cttttacgtc
    11881 tatgtatttt taaaaaaatg agcgaattat gattcgatag attgaccagc gggtttaaag
    11941 ttggtgctag cctatttctt aagcgatttt ccttttctag gataaagcag atcctgcttg
    12001 cttaacccca attttccacg atgaatccaa tagtaaatgg ttgaaattcc cacgttaacc
    12061 cctttagcca taaccatcat ttcaggcgaa aatttttggt tatg
//
LOCUS       DAVBOD010000058        11821 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 640-05
            SAMEA1012484-rid20186543.denovo.058, whole genome shotgun sequence.
ACCESSION   DAVBOD010000058 DAVBOD010000000
VERSION     DAVBOD010000058.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012484
            Sequence Read Archive: ERR059358
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11821)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11821)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979948.1
            Genome Coverage       :: 595x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:03:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,266
            CDSs (total)                      :: 2,219
            Genes (coding)                    :: 2,091
            CDSs (with protein)               :: 2,091
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 71 of 128
            Pseudo Genes (incomplete)         :: 50 of 128
            Pseudo Genes (internal stop)      :: 33 of 128
            Pseudo Genes (multiple problems)  :: 22 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11821
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012484-rid20186543.denovo.058"
                     /strain="NIG 640-05"
                     /db_xref="taxon:1313"
     gene            389..616
                     /locus_tag="VQ862_001754"
     CDS             389..616
                     /locus_tag="VQ862_001754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000576349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3116057.1"
                     /translation="MIFKAFKTKKQRKRQVELLLTVFFDSFLIDLFLHLFGIVPFKLD
                     KILIVSLIIFPIISTSIYAYEKLFEKVFDKD"
     gene            904..3801
                     /gene="nanA"
                     /locus_tag="VQ862_001755"
     CDS             904..3801
                     /gene="nanA"
                     /locus_tag="VQ862_001755"
                     /EC_number="3.2.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014632427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored neuraminidase NanA"
                     /protein_id="HET3116058.1"
                     /translation="MNRSVQERKCRYSIRKLSVGAVSMIVGAVVFGTSPVLAQEGASE
                     QPLANETQLSGESSTLTDTEKSQPSSETELSGNKQEQERKDKQEEKIPRDYYARDLEN
                     VETVIEKEDVETNASNGQRVDLSSELDKLKKLENATVHMEFKPDAKAPAFYNLFSVSS
                     ATKKDEYFTMAVYNNTATLEGRGSDGKQFYNNYNDAPLKVKPGQWNSVTFTVEKPTAE
                     LPKGRVRLYVNGVLSRTSLKSGNFIKDMPDVTHVQIGATKRANNTVWGSNLQIRNLTV
                     YNRALTPEEVQKRSQLFKRSDLEKKLPEGAALTEKTDIFESGRNGKPNKDGIKSYRIP
                     ALLKTDKGTLIAGADERRLHSSDWGDIGMVIRRSEDNGKTWGDRVTITNLRDNPKASD
                     PSIGSPVNIDMVLVQDPETKRIFSIYDMFPEGKGIFGMSSQKEEAYKKIDGKTYQILY
                     REGEKGAYTIRENGTVYTPDGKATDYRVVVDPVKPAYSDKGDLYKGNQLLGNIYFTTN
                     KTSPFRIAKDSYLWMSYSDDDGKTWSAPQDITPMVKADWMKFLGVGPGTGIVLRNGPH
                     KGRILIPVYTTNNVSHLNGSQSSRVIYSDDHGKTWHAGEAVNDNRQVDGQKIHSSTMN
                     NKRAQNTESTVVQLNNGDVKLFMRGLTGDLQVATSKDGGVTWEKDIKRYPQVKDVYVQ
                     MSAIHTMHEGKEYIILSNAGGPKRENGMVHLARVEENGELTWLKHNPIQKGEFAYNSL
                     QELGNGEYGILYEHTEKGQNAYTLSFRKFNWDFLSKDLISPTEAKVKRTREMGKGEMG
                     KGVIGLEFDSEVLVNKAPTLQLANGKTATFLTQYDSKTLLFAVDKEDIGQEIIGIAKG
                     SIESMHNLPVNLAGARVPGGVNGSKAAVHEVPEFTGGVNGTEPAVHEIAEYKGSDSLV
                     TLTTKEDYTYKAPLAQQALPETGNKESDLLASLGLTAFFLGLFTLGKKREQ"
     gene            4815..5267
                     /locus_tag="VQ862_001756"
     CDS             4815..5267
                     /locus_tag="VQ862_001756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000587452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HET3116059.1"
                     /translation="MIITKISRLGTYVGVNPHFATLIDFLEKTGLENLTEGSIAIDGN
                     RLFGNCFTYLADGQAGAFFETHQKYLDIHLVLENEEAMAVTSPENVSVTQEYDEEKDI
                     ELYTGKVEQLVHLRAGECLITFPEDLHQPKVRINDEPVKKVVFKVAIS"
     gene            5286..6623
                     /locus_tag="VQ862_001757"
     CDS             5286..6623
                     /locus_tag="VQ862_001757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HET3116060.1"
                     /translation="MKKMRKFLCLAGIALAAVALVACSGKKEATTSTEPPTELSGEIT
                     MWHSFTQGPRLESIQKSADAFMQKHPKTKIKIETFSWNDFYTKWTTGLANGNVPDIST
                     ALPNQVMEMVNSDALVPLNDSIKRIGQDKFNETALNEAKIGDDYYSVPLYSHAQVMWV
                     RTDLLKEHNIEVPKTWDQLYEASKKLKEAGVYGLSVPFGTNDLMATRFLNFYVRSGGG
                     SLLTKDLKADLTSQLAQDGIKYWVKLYKEISPQDSLNFNVLQQATLFYQGKTAFDFNS
                     GFHIGGINANSPQLIDSIDAYPIPKIKESDKDQGIETSNIPMVVWKNSKHPEVAKAFL
                     EALYNEEDYVKFLDSTPVGMLPTIKGISDSAAYKENETRKKFKHAEEVITEAVKKGTA
                     IGYENGPSVQAGMLTNQHIIEQMFQDIITNGTDPMKAAKEAEKQLNDLFEAVQ"
     gene            6702..7586
                     /locus_tag="VQ862_001758"
     CDS             6702..7586
                     /locus_tag="VQ862_001758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HET3116061.1"
                     /translation="MVKERNLTRWIFVLPAMIIVGLLFVYPFFSSIFYSFTNKHLIMP
                     NYKFVGLANYKAVLSDPNFFNAFFNSIKWTIFSLVGQVLVGFVLALALHRVRHFKKLY
                     RTLLIVPWAFPTIVIAFSWQWILNGVYGYLPNLIVKLGLMEHTPAFLTDSTWAFLCLV
                     FINIWFGAPMIMVNVLSALQTVPEEQFEAAKIDGASSWQVFKFIVFPHIKVVVGLLVV
                     LRTVWIFNNFDIIYLITGGGPANATTTLPIFAYNLGWGTKLLGRASAVTVLLFIFLVA
                     ICFIYFAIISKWEKEGRK"
     gene            7586..8419
                     /locus_tag="VQ862_001759"
     CDS             7586..8419
                     /locus_tag="VQ862_001759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HET3116062.1"
                     /translation="MKKKSSIYLDILSHVLLVGATIVAIFPLVWIIISSVKGKGELTQ
                     YPTRFWPEQFTLDYFTHVINDLHFIDNIRNSLIIALATTLIAIIISAMAAYGIVRFFP
                     KLGAIMSRLLVITYIFPPILLAIPYSIAIAKVGLTNSLFGLMMVYLSFSVPYAVWLLV
                     GFFQTVPIGIEEAARIDGANKFVTFYKVVLPIVAPGIVATAIYTFINAWNEFLYALIL
                     INNTGKMTVAVALRSLNGSEILDWGDMMAASVIVVLPSIIFFSIIQNKIASGLSEGSV
                     K"
     gene            8437..10530
                     /gene="nanB"
                     /locus_tag="VQ862_001760"
     CDS             8437..10530
                     /gene="nanB"
                     /locus_tag="VQ862_001760"
                     /EC_number="3.2.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="neuraminidase NanB"
                     /protein_id="HET3116063.1"
                     /translation="MNKRGLYSKLGISVVGISLLMGVPTLIHANELNYGQLSISPIFQ
                     GGSYQLNNKSIDISSLLLDKLSGESQTVVMKFKADEPNSLQALFGLSNSKAGFKNNYF
                     SIFMRDSGEIGVEIRDAQKGINYLFSRPASLWGKHKGQAVENTLVFVSDSKDKTYTMY
                     VNGIEVFSETVDTFLPISNINGIDKATLGAVNREGKEHYLAKGSIDEISLFNKAISDQ
                     EVSNIPLSNPFQLIFQSGDSTQANYFRIPTLYTLSSGRVLSSIDARYGGTHDSKSKIN
                     IATSYSDDNGKTWSEPIFAMKFNDYEEQLVYWPRDNKLKNSQISGSASFIDSSIVEDK
                     KSGKTILLADVMPAGIGNNNANKADSGFKEINGHYYLKLKKNGDNDFRYTVRENGVVY
                     DETTNKPTNYTINDKYEVLEGGKSLTVEQYSVDFDSGSLREKHNGKQVPMNVFYKDSL
                     FKVTPTNYIAMTTSQNRGESWEQFKLLPPFLGEKHNGTYLCPGQGLALKSSNRLIFAT
                     YTSGELTYLISDDSGQTWKKSSASIPFKNATAEAQMVELRDGVIRTFFRTTTGKIAYM
                     TSRDSGETWSEVSYIDGIQQTSYGTQVSAIKYSQLIDGKEAVILSTPNSRSGRKGGQL
                     VVGLVNKEDDSIDWKYHYDIDLPSYGYAYSAITELPNHHIGVLFEKYDSWSRNELHLS
                     NVVQYIDLEINDLTK"
     gene            10542..11645
                     /locus_tag="VQ862_001761"
     CDS             10542..11645
                     /locus_tag="VQ862_001761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HET3116064.1"
                     /translation="MVKYGVVGAGYFGAELARYMQKNDGAEITLLYDPDNAEAIAEEL
                     GAKVASSLDELVSSDEVDCVIVATPNNLHKEPVIKAAQHGKNVFCEKPIALSYQDCRE
                     MVDVCKENNVTFMAGHIMNFFNGVHHAKELINQGVIGDVLYCHTARNGWEEQQPSVSW
                     KKIREKSGGHLYHHIHELDCVQFLMGGMPETVTMTGGNVAHEGEHFGDEDDMIFVNME
                     FSNKRFALLEWGSAYRWGEHYVLIQGSKGAIRLDLFNCKGTLKLDGQESYFLIHESQE
                     EDDDRTRIYHSTEMDGAIAYGKPGKRTPLWLSSVIDKEMRYLHEIMEGAPVSEEFAKL
                     LTGEAALEAIATADACTQSMFEDRKVRLSEIVK"
BASE COUNT         3996 a         1844 c         2452 g         3529 t
ORIGIN      
        1 gtgttttgag ttgactttgt cagtcttatc tacagcctca aaacagtgtt ttgagcatca
       61 tgcggctagc ttcttagttt gctctttgat tttcattgag tataaaaaca gatgagtttc
      121 tgttttcttt ttatggacta taaatgttca gctgaaacta ctttcaagga cattattata
      181 taaaagaatt ttttgaaact aaaatctact atattacact atattgaaag cgttttaaaa
      241 atgaggtata ataaatttac taacacttat aaaaagtgat agaatctatc tttatgtata
      301 tttaaagata gattgctgta aaaatagtag tagctatgcg aaataacaga tagagagaag
      361 ggattgaagc ttagaaaagg ggaataatat gatatttaag gcattcaaga caaaaaagca
      421 gagaaaaaga caagttgaac tacttttgac agtttttttt gacagttttc tgattgattt
      481 atttcttcac ttatttggga ttgtcccctt taagctggat aagattctga ttgtgagctt
      541 gattatattt cccattattt ctacaagtat ttatgcttat gaaaagctat ttgaaaaagt
      601 gttcgataag gattgagcag gaagtatggt gtaaatagca taagctgatg tccatcattt
      661 gcttataaag agatatttta gtttaattgc agcggtgtcc tggtagataa actagattgg
      721 caggagtctg attggagaaa ggagagggga aaattggcac caatttgaga tagtttgttt
      781 agttcatttt tgtcatttaa atgaactgta gtaaaagaaa gttaataaaa gacaaactaa
      841 gtgcattttc tggagtaaat gtcttatttc agaaatcggg atatagatat agagaggatc
      901 agtatgaatc ggagtgttca agaacgtaag tgtcgttata gcattaggaa actatcggta
      961 ggagcggttt ctatgattgt aggagcagtg gtatttggaa cgtctcctgt tttagctcaa
     1021 gaaggggcaa gtgagcaacc tctggcaaat gaaactcaac tttcggggga gagctcaacc
     1081 ctaactgata cagaaaagag ccagccttct tcagagactg aactttctgg caataagcaa
     1141 gaacaagaaa ggaaagataa gcaagaagaa aaaattccaa gagattacta tgcacgagat
     1201 ttggaaaatg tcgaaacagt gatagaaaaa gaagatgttg aaaccaatgc ttcaaatggt
     1261 cagagagttg atttatcaag tgaactagat aaactaaaga aacttgaaaa cgcaacagtt
     1321 cacatggagt ttaagccaga tgccaaggct ccagcgttct ataatctctt ttctgtgtca
     1381 agtgctacta aaaaagatga gtacttcact atggcagttt acaataatac tgctactcta
     1441 gaggggcgtg gttcggatgg gaaacagttt tacaataatt acaacgacgc acccttaaaa
     1501 gttaaaccag gtcagtggaa ttctgtgact ttcacagttg aaaaaccgac agcagaacta
     1561 cctaaaggcc gagtgcgcct ctacgtaaac ggggtattat ctcgaacaag tctgaaatct
     1621 ggcaatttca ttaaagatat gccagatgta acgcatgtgc aaatcggagc aaccaagcgt
     1681 gccaacaata cggtttgggg gtcaaatcta cagattcgga atctcactgt gtataatcgt
     1741 gctttaacac cagaagaggt acaaaaacgt agtcaacttt ttaaacgctc agatttagaa
     1801 aaaaaactac ctgaaggagc ggctttaaca gagaaaacgg acatattcga aagcgggcgt
     1861 aacggtaaac caaataaaga tggaatcaag agttatcgta ttccagcact tctcaagaca
     1921 gataaaggaa ctttgatcgc aggtgcagat gaacgccgtc tccattcgag tgactggggt
     1981 gatatcggta tggtcatcag acgtagtgaa gataatggta aaacttgggg tgaccgagta
     2041 accattacca acttacgtga caatccaaaa gcttctgacc catcgatcgg ttcaccagtg
     2101 aatatcgata tggtgttggt tcaagatcct gaaaccaaac gaatcttttc tatctatgac
     2161 atgttcccag aagggaaggg aatctttgga atgtcttcac aaaaagaaga agcctacaaa
     2221 aaaatcgatg gaaaaaccta tcaaatcctc tatcgtgaag gagaaaaggg agcttatacc
     2281 attcgagaaa atggtactgt ctatacacca gatggtaagg cgacagacta tcgcgttgtt
     2341 gtagatcctg ttaaaccagc ctatagcgac aagggtgatc tatacaaggg taaccaatta
     2401 ctaggcaata tctacttcac aacaaacaaa acttctccat ttagaattgc caaggatagc
     2461 tatctatgga tgtcctacag tgatgacgac gggaagacat ggtcagcgcc tcaagatatt
     2521 actccgatgg tcaaagccga ttggatgaaa ttcttgggtg taggtcctgg aacaggaatt
     2581 gtacttcgga atgggcctca caagggacgg attttgatac cggtttatac gactaataat
     2641 gtatctcact taaatggctc gcaatcttct cgtgtcatct attcagatga tcatggaaaa
     2701 acttggcatg ctggagaagc ggtcaacgat aaccgtcagg tagacggtca aaagatccac
     2761 tcttctacga tgaacaataa acgtgcgcaa aatacagaat caacggtggt acaactaaac
     2821 aatggagatg ttaaactctt tatgcgtggt ttgactggag atcttcaggt tgctacaagt
     2881 aaagacggag gagtgacttg ggagaaggat atcaaacgtt atccacaggt taaagatgtc
     2941 tatgttcaaa tgtctgctat ccatacgatg cacgaaggaa aagaatacat catcctcagt
     3001 aatgcaggtg gaccgaaacg tgaaaatggg atggtccact tggcacgtgt cgaagaaaat
     3061 ggtgagttga cttggctcaa acacaatcca attcaaaaag gagagtttgc ctataattcg
     3121 ctccaagaat taggaaatgg ggagtatggc atcttgtatg aacatactga aaaaggacaa
     3181 aatgcctata ccctatcatt tagaaaattt aattgggact ttttgagcaa agatctgatt
     3241 tctcctaccg aagcgaaagt gaagcgaact agagagatgg gcaaaggaga gatgggcaaa
     3301 ggagttattg gcttggagtt cgactcagaa gtattagtca acaaggctcc aacccttcaa
     3361 ttggcaaatg gtaaaacagc gactttccta acccagtatg atagcaagac cttgttattt
     3421 gcagtagata aggaagatat cggacaggaa attattggta tagctaaagg aagcatcgaa
     3481 agtatgcata atcttcctgt aaatctagca ggtgccagag ttcctggcgg agtaaatggt
     3541 agcaaagcag cggtgcatga agttccagaa tttacagggg gagttaatgg tacagagcca
     3601 gctgttcatg aaatcgcaga gtataaggga tctgattcgc ttgtaactct tactacaaaa
     3661 gaagattata cttacaaagc tcctcttgct cagcaggcac ttcctgaaac aggaaacaag
     3721 gagagtgacc tcctagcttc actaggacta acagctttct tccttggtct gtttacgcta
     3781 gggaaaaaga gagaacaata agagaagaat tctaaacatt tgattttgta aaaatagaag
     3841 gagatagcag gttttcaagc ctgctatctt tttttgatga cattcaagct gatacgaaat
     3901 cataagaggt ctgaaactac tttcagagta gtctgttcta taaaatatag tagattgaaa
     3961 taagatgtga acaactctat caggaaagtc aaattaattt atagaaaaat tttagcagtc
     4021 aaggtgtact gttatgtatt caatatatta tacggctatt aaccttgtct tctcctaaaa
     4081 ttgactttct tgttttctta tcttgtccac tcgaaacaag tattgtaaga atttgattat
     4141 ttttgaaagt acttttaata tacttgatat agttaaaaaa gatttgaaac taaattccaa
     4201 attagaaaaa gacttgaaat actaaaaaaa aaagtatact ctaattgaaa acggtaacaa
     4261 aactaattta gagaatgaaa tatagagtat ttctctctta aaagtttttg gtgaaacgag
     4321 atgtagaaag gagatttagc caaagagtct attagtgcta gaataataga ttagaattat
     4381 tttagaaaaa cgaagtgagc agcttataaa ttcaagtccc caaatagatt catactagta
     4441 tcttttgcaa aaaataaagg gcgacttcct tcatgaatat caatttcatc tataaggaag
     4501 gtagctaatt gaactaactt atttattctg tttgtcgcta gaaaaatcag acctccttgt
     4561 gaagattgag gagatactta atgaaaatca aagaagaaac tagcaagcta gtagcagatt
     4621 gcccaaaaca ccgctttgag gttgtagata agactgacgt atataatcca aggtgaagcg
     4681 actgtggttt gaagagattt tcaaagagta taggctagag agtagtgttt ttatgtcctt
     4741 ctagtagaaa atgctagaca gaagaatggg gaacttggat aggaaaaata gattgagaaa
     4801 ggaggttaga agagatgatt attacaaaaa ttagccgttt aggaacttat gtgggagtaa
     4861 atccacattt tgcaacatta atagattttc tagaaaaaac aggactagaa aatttaacag
     4921 aaggttcgat tgctatcgat ggtaatcgat tgtttgggaa ttgctttact tatctagcag
     4981 atggtcaagc aggggctttc tttgaaacac accaaaaata tttggatatt catttagttt
     5041 tggaaaacga agaagccatg gctgttacat cgccggaaaa tgtaagcgtt acccaagaat
     5101 atgatgaaga gaaagatatt gaattataca cagggaaagt ggaacagttg gttcatttga
     5161 gagctggcga atgcctcatc acttttccag aagatttaca tcaacccaag gttcgtataa
     5221 atgatgaacc tgtgaaaaaa gttgtcttta aagttgcgat ttcttaatgt agaaagagaa
     5281 gaacgatgaa aaaaatgaga aagtttttat gtctagctgg aattgcgcta gcggctgttg
     5341 ccttggtagc ttgttcagga aaaaaagaag ctacaactag tactgaacca ccaacagaat
     5401 tatctggtga gattacaatg tggcactcct ttactcaagg accccgttta gaaagtattc
     5461 aaaaatcagc agatgctttc atgcaaaagc atccaaaaac gaaaatcaag attgaaacat
     5521 tttcttggaa tgacttctat actaaatgga ctacaggttt agcaaatgga aatgtgccag
     5581 atatcagtac agctcttcct aaccaagtaa tggaaatggt caactcagat gctttggttc
     5641 cgttaaatga ttctatcaag cgtattggac aagataaatt taacgaaact gccttaaatg
     5701 aagcaaaaat cggagatgat tactactctg ttcctcttta ttcacatgca caagtcatgt
     5761 gggttagaac agatttgtta aaagaacata atattgaggt tcctaaaact tgggatcaac
     5821 tctatgaagc ttctaaaaaa ttgaaagaag ctggagttta tggcttgtct gttccgtttg
     5881 gaacaaatga cttaatggca acacgtttct tgaacttcta cgtacgtagt ggtggaggaa
     5941 gcctcttaac aaaagatctt aaagcagact tgacaagcca acttgctcaa gatggtatta
     6001 aatactgggt taaattgtat aaagaaatct cacctcaaga ttctttgaac tttaatgtcc
     6061 ttcaacaagc taccttgttc tatcaaggaa aaacagcatt tgactttaac tctggcttcc
     6121 atatcggagg aattaatgcc aacagtcctc aattgattga ttcgattgat gcttatccta
     6181 ttccaaaaat caaagagtct gataaagacc aaggaattga aacctcaaac attccaatgg
     6241 ttgtttggaa aaattcaaaa catccagaag ttgctaaagc attcttagaa gcactttata
     6301 atgaagaaga ctacgttaaa ttccttgatt caactccagt aggtatgttg ccaactatta
     6361 aggggattag cgattctgca gcctataaag aaaatgaaac tcgtaagaaa tttaaacatg
     6421 ctgaagaagt aattactgaa gctgttaaaa aaggtactgc tattggttat gaaaatggac
     6481 caagtgtaca agctggtatg ttgactaacc aacacattat tgaacaaatg ttccaagata
     6541 tcattacaaa tggaacagat cctatgaaag cagcaaaaga agcagaaaaa caattaaatg
     6601 atttatttga ggctgttcag tagatgtaaa agactagaaa ataggtgggc tagtgagctg
     6661 aaaagctcta gcccaatctt gtaaaagaag ggagaaggag aatggttaaa gaacgtaatt
     6721 taactcgctg gatatttgtt ttgccagcta tgattatcgt aggattactc tttgtttatc
     6781 cgtttttctc gagtattttt tatagcttta ccaataagca tttgattatg cctaattata
     6841 aatttgttgg tttggctaac tataaagctg tgctatcaga tcccaacttc tttaatgcgt
     6901 tctttaattc aattaagtgg accattttct cattagttgg tcaagtttta gtagggtttg
     6961 tattggcttt agctcttcac agagtacgcc acttcaagaa attatatagg accttattga
     7021 ttgttccttg ggcatttcct accatcgtta ttgccttctc ttggcagtgg attctaaacg
     7081 gggtttatgg ctacttacct aatctaatcg taaaattagg tttaatggaa catacacctg
     7141 catttttgac agatagtaca tgggcattcc tatgtttggt gtttatcaac atttggtttg
     7201 gagcaccaat gattatggtt aatgtgcttt cagctttgca aacagtacca gaagaacaat
     7261 ttgaggctgc taagatagat ggtgcttcaa gttggcaggt gttcaagttt atcgtctttc
     7321 cacatattaa agtggttgta ggacttctag ttgttttgag aactgtatgg atctttaata
     7381 actttgacat tatctacctc attactggtg gtggaccagc caatgctaca acgacgcttc
     7441 caatttttgc ttacaacctg ggctggggaa ctaaattgtt gggtcgtgct tcagcagtta
     7501 cagtattgct ctttatcttc ttggtggcga tttgctttat ctactttgct atcatcagta
     7561 agtgggaaaa ggagggtaga aaataatgaa gaagaaatcc agtatttatt tagatattct
     7621 ctcacatgta cttttagttg gtgcgaccat cgttgcaatt ttcccattgg tatggattat
     7681 catatcttct gtcaaaggga aaggggaatt aactcagtat ccaacacgat tttggcctga
     7741 acagtttaca ttagattatt tcactcatgt tatcaacgat ttgcacttca ttgataacat
     7801 tcgaaacagt ttaatcattg ccttggctac aacccttatt gcgattatta tttctgctat
     7861 ggcagcctat ggtattgttc gattctttcc taaattggga gcaatcatgt cgagactact
     7921 cgtcattacc tacattttcc caccaatttt gttagcaatt ccctattcaa ttgccattgc
     7981 taaagttggg ttaacaaata gtttatttgg cttgatgatg gtttatctat cttttagtgt
     8041 tccatatgca gtttggctct tagttggatt tttccaaaca gttccaattg gaattgaaga
     8101 agcggctaga attgatggtg caaataaatt tgttacgttt tataaagttg tgctaccgat
     8161 tgtagcacca ggtattgtag caacagctat ttatacattt atcaatgctt ggaatgaatt
     8221 cctgtatgcc ttgattttga ttaacaatac aggaaagatg acagtagcag tagcccttcg
     8281 ttcacttaat ggttcagaaa tactagactg gggagatatg atggcagcgt ctgttattgt
     8341 agttcttcca tcaattattt tcttctctat catccaaaat aagattgcaa gtggattatc
     8401 agaaggatct gtgaagtaga cgaaagaagg aaaaaaatga ataaaagagg tctttattca
     8461 aaactaggaa tttctgttgt aggcattagt cttttaatgg gagttcccac tttgattcat
     8521 gcgaatgaat taaactatgg tcaactgtcc atatctccta tttttcaagg aggttcatat
     8581 caactgaaca ataagagtat agatatcagc tctttgttat tagataaatt gtctggagag
     8641 agtcagacag tagtaatgaa atttaaagca gatgaaccaa actctcttca agctttgttt
     8701 ggcctatcta atagtaaagc aggctttaaa aataattact tttcaatttt catgagagat
     8761 tctggtgaga taggtgtaga aataagagac gcccaaaagg gaataaatta tttattttct
     8821 agaccagctt cattatgggg aaagcataaa ggacaggcag ttgaaaatac actagtattt
     8881 gtatctgatt ctaaagataa aacatacaca atgtatgtta atggaataga agtgttctct
     8941 gaaacagttg atacattttt gccaatttca aatataaatg gtatagataa ggcaacacta
     9001 ggagctgtta atcgtgaagg taaggaacat tacctcgcaa aaggaagtat tgatgaaatc
     9061 agtctattta acaaagcaat tagtgatcag gaagtttcaa atattccctt gtcaaatcca
     9121 tttcagttaa ttttccaatc aggagattct actcaagcta actattttag aataccgaca
     9181 ctatatacat taagtagtgg aagagttcta tcaagtattg atgcacgtta tggtgggact
     9241 catgattcta aaagtaagat taatattgcc acttcttata gtgatgataa tgggaaaacg
     9301 tggagtgagc caatttttgc tatgaagttt aatgactatg aggagcagtt agtttactgg
     9361 ccacgagata ataaattaaa gaatagtcaa attagtggaa gtgcttcatt catagattca
     9421 tccattgttg aagataaaaa atctgggaaa acgatattac tagctgatgt tatgcctgcg
     9481 ggtattggaa ataataatgc aaataaagcc gactcaggtt ttaaagaaat aaatggtcat
     9541 tattatttaa aactaaagaa gaatggagat aacgatttcc gttatacagt tagagaaaat
     9601 ggtgtcgttt atgatgaaac aactaataaa cctacaaatt atactataaa tgataagtat
     9661 gaagttttgg agggaggaaa gtctttaaca gtcgaacaat attcggttga ttttgatagt
     9721 ggctctttaa gagaaaaaca taatggaaaa caggtcccaa tgaatgtttt ctacaaagat
     9781 tcgttattta aagtgactcc tactaattat atagcaatga caactagtca gaatagagga
     9841 gagagttggg aacaatttaa gttgttgcct ccgttcttag gagaaaaaca taatggaact
     9901 tacttatgtc ccggacaagg tttagcatta aaatcaagta acagattgat ttttgcaaca
     9961 tatactagtg gagaactaac ctatctcatt tctgatgata gtggtcaaac atggaagaaa
    10021 tcctcagctt caattccgtt taaaaatgca acagcagaag cacaaatggt tgaactgaga
    10081 gatggtgtga ttagaacatt ctttagaacc actacaggta agatagctta tatgactagt
    10141 agagattctg gagaaacatg gtcggaagtt tcgtatattg atggaatcca acaaacttca
    10201 tatggcacac aagtatctgc aattaaatac tctcaattaa ttgatggaaa agaagcagtc
    10261 attttgagta caccaaattc tagaagtggc cgtaagggag gtcaattagt tgtcggttta
    10321 gtcaataaag aagatgatag tattgattgg aaataccact atgatattga tttgccttcg
    10381 tatggttatg cctattctgc gattacagaa ttgccaaatc atcacatagg tgtactgttt
    10441 gaaaaatatg attcgtggtc gagaaatgaa ttgcatttaa gcaatgtagt tcagtatata
    10501 gatttggaaa ttaatgattt aacaaaataa aggagaaaaa catggttaaa tacggtgttg
    10561 ttggagcagg gtattttgga gctgaattgg ctcgctacat gcaaaaaaat gatggagcag
    10621 agattactct tctctatgat ccagataatg cagaggcgat tgcagaagaa ttgggagcaa
    10681 aagtagcaag ttccttagat gagttggttt ctagcgatga agtagactgt gttatcgtcg
    10741 caactccaaa taatcttcat aaggaaccgg ttattaaggc tgcacagcat ggtaaaaatg
    10801 ttttctgtga aaaaccaatt gcgctttctt atcaagattg tcgcgagatg gtagatgtgt
    10861 gtaaagaaaa caatgtaacc tttatggcag gacatattat gaatttcttt aatggtgttc
    10921 atcatgcaaa agaactcatt aatcaaggag ttatcggaga cgttctatat tgtcatacag
    10981 ctcgtaatgg ttgggaagaa caacaaccgt cagtatcatg gaaaaaaatt cgtgaaaaat
    11041 caggtggtca cttgtatcac cacatccatg aattggattg cgttcaattc cttatggggg
    11101 gcatgcctga aactgtaacc atgacaggtg gaaatgtggc ccatgaaggt gaacatttcg
    11161 gtgatgaaga tgatatgatt tttgtcaata tggaattttc taataagcgt tttgctttgt
    11221 tagaatgggg ttcagcttat cgttggggtg aacattatgt cttaatccaa ggaagcaaag
    11281 gtgccatccg cttagactta ttcaactgta aaggaactct taagctagat gggcaagaaa
    11341 gctatttctt gattcacgaa tcgcaagaag aagatgatga tcggactcgt atctatcata
    11401 gtacagagat ggatggagca attgcttatg gtaaaccagg taaacgtact ccattatggc
    11461 tatcatctgt cattgataaa gaaatgcgct atctgcatga gattatggaa ggagctccag
    11521 tatcagaaga atttgcaaaa cttttgacag gtgaagctgc cctagaagca attgctactg
    11581 cagatgcttg tacccagtct atgtttgaag atcgcaaagt aagattgtca gaaattgtaa
    11641 aataaatttt ggtattctcc tatctatagg tcgacttgct cctctgaaag tacttttaga
    11701 ggagctgttt gactttgcta gtttttgaaa ctgaaatcta ttatactaca aactattgaa
    11761 agcgttttaa ttttaaggta taataatctc atagaaataa agaaaaggag gaaagaggat
    11821 g
//
LOCUS       DAVBOD010000059        11716 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 640-05
            SAMEA1012484-rid20186543.denovo.059, whole genome shotgun sequence.
ACCESSION   DAVBOD010000059 DAVBOD010000000
VERSION     DAVBOD010000059.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012484
            Sequence Read Archive: ERR059358
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11716)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11716)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979948.1
            Genome Coverage       :: 595x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:03:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,266
            CDSs (total)                      :: 2,219
            Genes (coding)                    :: 2,091
            CDSs (with protein)               :: 2,091
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 71 of 128
            Pseudo Genes (incomplete)         :: 50 of 128
            Pseudo Genes (internal stop)      :: 33 of 128
            Pseudo Genes (multiple problems)  :: 22 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11716
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012484-rid20186543.denovo.059"
                     /strain="NIG 640-05"
                     /db_xref="taxon:1313"
     gene            complement(122..604)
                     /gene="greA"
                     /locus_tag="VQ862_001762"
     CDS             complement(122..604)
                     /gene="greA"
                     /locus_tag="VQ862_001762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018370745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription elongation factor GreA"
                     /protein_id="HET3116065.1"
                     /translation="MAEKTYPMTLEEKEKLEKELEELKLVRRPEVVERIKIARSYGDL
                     SENSEYEAAKDEQAFVEGQISSLETKIRYAEIVNSDAVAQDEVAIGKTVTIQEIGEDE
                     EEVYIIVGSAGADAFAGKVSNESPIGQALIGKKTGDTATIETPVGSYDVKILKVEKTA
                     "
     gene            complement(675..2330)
                     /gene="mltG"
                     /locus_tag="VQ862_001763"
     CDS             complement(675..2330)
                     /gene="mltG"
                     /locus_tag="VQ862_001763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001291636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endolytic transglycosylase MltG"
                     /protein_id="HET3116066.1"
                     /translation="MSEKSREEEKLSFKEQILRDLEKVKGYDEVLKEDEAVVRTPANE
                     PSAEELMADSLSTVEEIMRKAPTVPTHPSQGVPASPADEIQRETPGVPSHPSQDVPSS
                     PAEESGSRPGPGPVRPKKLEREYNETPTRVAVSYTTAEKKAEQAGPETPTPATETVDI
                     ISDTSRRSRREGAKPVKPKKEKKSHVKAFVISFLVFLALLSAGGYFGYQYVLDSLLPI
                     DANSKKYVTVGIPEGSNVQEIGTTLEKAGLVKHGLIFSFYAKYKNYTDLKAGYYNLQK
                     SMSTEDLLKELQKGGTDEPQEPVLATLTIPEGYTLDQIAQTVGQLQGDFKESLTAEAF
                     LAKVQDETFISQAVAKYPTLLESLPVKDSGARYRLEGYLFPATYSIKESTTIESLIDE
                     MLAAMDKNLSPYYSTIKSKNLTINELLTIASLVEKEGAKTEDRKLIAGVFYNRLNRDM
                     PLQSNIAILYAQGKLGQNISLAEDVAIDTDIDSPYNVYKNVGLMPGPVDSPSLDAIES
                     SINQTKSDNLYFVADVTEGKVYYANNQEDHDRNVAEHVNSKLN"
     gene            complement(2411..2905)
                     /locus_tag="VQ862_001764"
     CDS             complement(2411..2905)
                     /locus_tag="VQ862_001764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000702438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET3116067.1"
                     /translation="MKIRQARLEDLDRIVELEFENFSVEEAIPPSVFEAHLREIQTSF
                     LVAEKEGRIMGYIEGPVGLHRHLQDQSFTEEIKDYSHEPGGYISVTCLSIAKEAQGLG
                     LGQKLLTALKEVALEDERDGINLTCHDYLIAYYEKHGFVNEGQSQSTFAGETWYDMVW
                     EMKK"
     gene            complement(2902..3366)
                     /locus_tag="VQ862_001765"
     CDS             complement(2902..3366)
                     /locus_tag="VQ862_001765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET3116068.1"
                     /translation="MEIPIKIIQASKSDLPEIGALQTSSFPAEKQQLSHILEESIRKC
                     ADTFLLARDENQLLGYILSSPQSDNPQYLKVHSLVIESDHQRQGLGTLLLAALKEVAV
                     DLDYKGIRLESPDELLSYFEMNGFVDEEATLLYATSQGYSMIWFNPFYLEEQ"
     gene            complement(3376..4710)
                     /locus_tag="VQ862_001766"
     CDS             complement(3376..4710)
                     /locus_tag="VQ862_001766"
                     /EC_number="6.3.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate--L-alanine ligase"
                     /protein_id="HET3116069.1"
                     /translation="MSKTYHFIGIKGSGMSALALMLHQMGHKVQGSDVEKYYFTQRGL
                     EQAGITILPFDEKNLDGDMEIIAGNAFRPDNNVEIAYADQNGISYKRYHEFLGSFMRD
                     FVSMGVAGAHGKTSTTGMLSHVLSHITDTSFLIGDGTGRGSANAKYFVFESDEYERHF
                     MPYHPEYSIITNIDFDHPDYFTSLEDVFNAFNDYAKQITKGLFVYGEDAELRKITSDA
                     PIYYYGFEAEGNDFVASDLIRSTTGSTFTVHFRGQNLGQFHIPTFGRHNIMNATAVIG
                     LLYTAGFDLNLVREHLKTFSGVKRRFTEKIVNDTVIIDDFAHHPTEIIATLDAARQKY
                     PSKEIVAVFQPHTFTRTIALLDDFAHALNQADAVYLAQIYGSAREVDHGDVKVEDLAN
                     KINKKHQVITVENVSPLLDHDNAVYVFMGAGDIQTYEYSFERLLSNLTSNVQ"
     gene            complement(4721..5338)
                     /locus_tag="VQ862_001767"
     CDS             complement(4721..5338)
                     /locus_tag="VQ862_001767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000808222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine gamma-synthase"
                     /protein_id="HET3116070.1"
                     /translation="MKQERFPLVSDDEVMLTEMPVMNLYDESDLISNIKGEYRDKNYL
                     EWAPIAEEKPVKPIEKQVGKPKKAPLGVKKEGKSYAEVAREEARADLKKKRSANYLTQ
                     DFSLARRHSQPSLVRQGNQPTTPFQKENPGEFVKYSQKLTQSHYILAEEVHSIPTKNE
                     EVSAPAPKKNNYDFLKKSQIYNKKSKQTEQERRVAQELNLTRMTE"
     gene            complement(5386..8484)
                     /locus_tag="VQ862_001768"
     CDS             complement(5386..8484)
                     /locus_tag="VQ862_001768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001096241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HET3116071.1"
                     /translation="MAKLIPGKIRIEGVALYETGKVDIIKEKNNRLYARVAEEELRYS
                     LEDDLVFCACDSFQKRGYCVHLAALEHFLKNDERGQEILWSLEEGHEEKEAVETKVTL
                     GGKFLNRILSPKSECAYELSAVGQVEAGTNHILWTLRIGQINSQKYYVIRDIPLFLRI
                     VEQRKSYMIGKIYEESLSWEAFDDASQELLTFLHGLTEEGLVPDLFFQNQGRHLFFPL
                     TFFEQGVNLLMALPHFQFDHQVDSYQTLLFQDMHADANLFAFTVTEYSDYFEMEISES
                     PRVNVFYQGAVLFHKGQVYFLTDQQMRLLKEIKALPVGQQGKKYLQFDSSDRDKLASC
                     LTLFIQMGTVSAPERLQIKTFAPSFYFDREEDNRIRLEIQFDYGNRQVSSRQELEELP
                     FSSDADLEERIFQVCLAAGFEADFQSWRQALKAESVYHFFHDIIPVFEKLGHVDLSDK
                     LEELYSLASPQVQIASKGGLLEIQFDFQNIAQEEIDQAMQALVANQDFYIDSSNQVYF
                     FDEETKKIRQNLQELGQFELKDGTLQARKSLAYSLAHLFEGRDRVSFSQEFQNLAQDL
                     THPEDFPLQATQVKADLRDYQEKGIGWLQMLHHYGFGGILADDMGLGKTLQTIAFLTS
                     QVTKESRVLILAPSGLIYNWADEFQKFAPQLDVAVVHGLKASREEILAESHQIYVTSY
                     ATFRQDSEFYQGMAFDFLFLDEAQVMKNAQTKIAQTLRQFVVPSVFALSGTPIENHLG
                     ELWSIFQIVMPGLLPSKKEFMKLPAERVAQFIKPFVMRRKKEEVLTELPDLIEVVYKN
                     ELEDQQKAIYLAQLQQMRDHLAQVSEQEFQRSRVEILSGLMRLRQICDTPALFMEDYQ
                     GASGKLDSLRDLLVQVADGGHRVLIFSQFKGMLEKIEQELSDLGLTSFKITGSTPAKE
                     RQDMTKAFNQGERDAFLISLKAGGVGLNLSGADTVILVDLWWNPAVEAQAIGRAHRMG
                     QEETVEVYRLVTKGTIEEKIQELQEQKKHLVSQVLDGTESRGSLTLAEIREILGISEA
                     ST"
     gene            complement(8577..9743)
                     /locus_tag="VQ862_001769"
     CDS             complement(8577..9743)
                     /locus_tag="VQ862_001769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000521357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HET3116072.1"
                     /translation="MGKYDFTSLPNRLGHHTYKWKETETDSEVLPAWIADMDFVVLPE
                     IRQAVQTYADQLVYGYTYASEDLIKEIQKWEATQYGYNFDKEALVFIEGVVPAISTAI
                     QTFTKEGEAVLINTPVYPPFARSVKLNNRRLITNSLVEKDGLFEIDFDQLEKDLVEEE
                     VKLYILCNPHNPGGRVWEKEVLEKIGQLCQKHGVLLVSDEIHQDLTLFGHKHQSFNTI
                     NPAFKNFAIVLSSATKTFNIAGTKNSYAVIENPKLRLAFQKRLLANNQHEISGLGYLA
                     TEAAYRYGKDWLEELKQVFEDHINYVVDLFGKETKIKVMKPQGTYLIWLDFSAYDLTD
                     ETLQELLRNEAKVILNRGLDFGEEGSLHARINIAMPKSLLQEVCQRIVATFAKR"
     gene            complement(9751..10845)
                     /locus_tag="VQ862_001770"
     CDS             complement(9751..10845)
                     /locus_tag="VQ862_001770"
                     /EC_number="2.5.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine gamma-synthase"
                     /protein_id="HET3116073.1"
                     /translation="MSKELHINTILAQAGIKSDEATGALVTPLHFSTTYQHPEFGRST
                     GFDYTRTKNPTRSKAEEVLAAIESADYALATSSGMSAIVLAFSVFPVGSKVLAVRDLY
                     GGSFRWFNQVEQEGRFHFTYANTEEELIAELEKDVDVLYIETPTNPLMLEFDIEKLAK
                     LAHAKGAKVVVDNTFYSPIYQRPIEDGADIVLHSATKYLAGHNDVLAGVVVTNSLELY
                     EKLFYNLNTTGAVLSPFDSYQLLRGLKTLSLRMERSTANAQEVVAFLKDSPAVKEVLY
                     TGRGGMISFKVADETRIPHILNSLKVFSFAESLGGVESLITYPTTQTHADIPAEVRHS
                     YGLTDDLLRLSIGIEDARDLIADLRQALEG"
     gene            complement(11003..11656)
                     /locus_tag="VQ862_001771"
     CDS             complement(11003..11656)
                     /locus_tag="VQ862_001771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012386829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HET3116074.1"
                     /translation="MFKGQKIAFVGPSGSGKSTIVRLLERFYKPLSGDILMEQSSIYD
                     FNLKEWRSKIAWVSQNNAVLSGSIRDNLCLGLNRLVTDDELMKVLDLVSLGDEIRSMK
                     EGLDTEVGERGRLLSGGQSQRLQIARAYLKDAEILIFDEATANLDADSEYAIISSLYS
                     VLKEKTVVIIAHRLSTVKDVDCIFFLEEGKITGSGTHKELLENHERYARFVQEQMIE"
BASE COUNT         3252 a         2680 c         2220 g         3564 t
ORIGIN      
        1 aagtcagtaa ccatacatac ggcaaggcga cgctgacgtg gtttgaagag attttcgaag
       61 agtagcaaaa tggaaaaagg agtgagtgaa gcacatcgcc tccccactcc tttttctgtt
      121 tttaggctgt tttttcaacc ttcaagattt ttacatcata gctaccaaca ggcgtttcaa
      181 tggttgctgt atcacctgtt ttcttgccaa tcaaggcctg cccaattggg ctttcatttg
      241 aaaccttacc tgcaaaggca tccgcaccag ctgaacctac gataatataa acttcttctt
      301 cgtcctcacc aatttcttgg atggtgactg ttttaccaat cgctacttcg tcctgggcaa
      361 ctgcgtcgct attgacgatt tcagcatagc ggatttttgt ttctaagcta gagatttgtc
      421 cttcgacaaa ggcttgttca tccttagctg cttcgtactc actgttttct gaaagatcac
      481 cgtatgaacg ggcaatctta atgcgttcta ccacttctgg tcgacgaacc aatttcaatt
      541 cttctaattc tttttcaagt ttctcctttt cctcaagggt cataggatat gttttttctg
      601 ccatttttct caactttctt ctgataatat tttctaaaga aaattatgtg aagtatcaca
      661 taattttagt ttgtttagtt taatttgctg ttgacatgtt cagcgacatt gcggtcgtgg
      721 tcttcttgat tgttagcata gtagaccttg ccttctgtga catctgctac aaagtagagg
      781 ttatcgctct tagtttgatt gatgcttgac tcaatcgcat ccagacttgg actatcgact
      841 ggaccaggca tgagacctac atttttataa acattataag gtgaatcaat gtcggtatca
      901 atcgcaacat cctcagctag actgatattt tgccccagtt ttccttgggc atacaagatt
      961 gcaatattac tttgaagtgg catatcacga tttaaacgat tgtagaatac acctgcaatg
     1021 agcttacgat cttctgtctt ggcaccttct ttttcgacca aggaagcaat ggtcaacaac
     1081 tcattgatag tcaagttttt agatttgata gtactatagt aaggagatag gttcttatcc
     1141 atagcagcta acatctcatc aatcaagctc tcaatagttg tgctttcctt gatagagtat
     1201 gtagctggga aaaggtatcc ttccaaacga taacgcgcac cgctgtcttt tacaggcaaa
     1261 ctttccagta aagtaggata tttcgctact gcttgactga taaacgtctc atcttgaact
     1321 ttagccaaga aagcctccgc tgtcaaagac tctttgaagt caccttgcaa ttgacccaca
     1381 gtttgagcaa tctgatccaa ggtataacct tctggaattg tcaaagtcgc aagtacaggt
     1441 tcttgcggtt catctgttcc acctttttgc aactctttga gtaagtcttc tgtactcata
     1501 ctcttttgca aattgtagta acctgctttc aagtcggtat aatttttata cttggcataa
     1561 aaactaaaaa tcagaccatg ctttaccaaa ccagcttttt caagcgtcgt accgatttct
     1621 tgaacgtttg aaccttctgg aattccaacc gtcacatatt tcttagaatt agcatcgata
     1681 ggtaacaaag aatctagcac gtactggtaa ccaaagtaac cacctgctga gagcaaggca
     1741 aggaatacaa ggaatgaaat cacaaaagct ttcacatgtg acttcttctc tttcttaggt
     1801 ttaacgggtt ttgctccttc tctacggcta cgacgtgatg tatcgctgat gatatccact
     1861 gtttctgtag caggcgtagg tgtttctgga cctgcttgtt ctgctttttt ctctgccgtc
     1921 gtataggaaa cagctaccct tgttggggtt tcattgtatt ctctttcaag tttcttaggt
     1981 ctaacaggac ctggacctgg tcttgatcca ctttcttccg ctggagaaga aggtacatct
     2041 tgacttggat gacttggaac accaggagtt tctctttgaa tctcatctgc tggagaagct
     2101 ggtacacctt gacttgggtg agtaggcacg gtaggagctt ttctcataat ctcctctacc
     2161 gttgacaagg aatcagccat gagttcttca gctgaaggtt catttgcagg agtgcgaact
     2221 actgcctcat cttctttcag aacttcatca tagcctttta ctttttctaa atctctcaga
     2281 atctgctctt taaagcttaa tttctcttct tctcttgact tttcactcaa aagtttttcc
     2341 tccttgttga taatccataa tattatatct taaaagtcca aaaaaagcaa tctatgatac
     2401 ttttcctaac ttattttttc atttcccaga ccatatcata ccatgtttcc cctgcaaagg
     2461 ttgactggga ctggccttcg ttgacaaatc catgtttttc ataataggcg atgagatagt
     2521 catgacaggt tagattaatg ccatctctct catcttcaag agcaacttct ttcaaggctg
     2581 tcagcaattt ctgacccagt ccgagtccct gtgcctcctt ggcaatagac agacaggtca
     2641 cagagatata accaccaggc tcatgactat agtcttttat ttcttctgta aaagactggt
     2701 cttgcagatg gcggtgcagg ccaactggtc cttcgatata acccatgatt cttccttctt
     2761 tttcagcaac cagaaaagag gtctgaattt ctctcaaatg tgcttcaaag acagaaggag
     2821 gaatggcttc ttcgaccgaa aaattttcaa attcaagttc aacaatccga tccaaatctt
     2881 ctaatcttgc ttgtctgatt ttcattgttc ctccagataa aagggattaa accaaatcat
     2941 actatagccc tggctagttg catagagcaa agttgcttct tcatcaacaa aaccgttcat
     3001 ttcaaaatag gaaagcagct catcaggact ctccaaacga atccctttgt aatccagatc
     3061 aactgccacc tctttcaagg ctgcaagaag aagtgttccc aagccctgtc tctgatggtc
     3121 agactcgatg actaaagaat gtacttttag atattgcgga ttgtctgact ggggacttga
     3181 taaaatatag cctaaaagtt gattttcatc cctagctaga agaaaggtat ccgcacactt
     3241 acggatactt tcttctaaaa tatgggaaag ttgctgcttt tcagctggaa aagacgaggt
     3301 ctgaagtgcc cctatctcag gcaaatcaga cttgcttgcc tgaatgatct taattggaat
     3361 ttccatggga acatcctatt gaacattgct tgtcaagtta gacaagagac gctcaaatga
     3421 gtattcatag gtttggatgt ctcctgctcc cataaagacg taaacagcat tgtcatggtc
     3481 taggagcgga gaaacatttt caacagtaat cacttggtgt tttttgttga ttttgttggc
     3541 taggtcttct accttaacgt caccatgatc tacttcacga gccgagccat aaatttgcgc
     3601 tagataaaca gcatctgctt ggtttaaagc atgggcaaag tcgtccaaca aggcaatggt
     3661 tcttgtaaag gtatgcggtt gaaagactgc tacaatttcc ttgcttgggt atttctgacg
     3721 agccgcatcc aaggtcgcaa taatttctgt tggatgatgg gcaaagtcat cgataatcac
     3781 tgtatcattg acaattttct cagtgaaacg acgtttaaca ccggaaaatg ttttcaagtg
     3841 ctcacgcacc aagttcaaat caaatcctgc tgtgtaaaga agaccaataa cggctgtcgc
     3901 attcatgata ttgtgacgac caaaggttgg aatgtggaat tgccccaagt tttgtccacg
     3961 gaaatgaacg gtgaaggttg aaccagttgt tgaacgaata agatcactag ctacaaagtc
     4021 attgccttca gcttcaaaac cataataata aattggtgca tcagacgtaa tcttacgcaa
     4081 ttcagcatct tcaccataga caaaaagacc cttggtgatt tgtttggcat agtcgttaaa
     4141 ggcattgaaa acatcctcga gacttgtgaa ataatctgga tggtcaaagt caatgttggt
     4201 gataatagag tattctgggt ggtaaggcat gaagtgacgc tcatattcgt cagattcaaa
     4261 gacaaaatat ttggcattgg ccgaaccacg acctgtccca tctccaatca agaagctggt
     4321 atctgtaatg tgagacaaga catgagacaa catacctgtc gttgaagttt ttccatgtgc
     4381 tcctgctact cccatgctaa caaagtcacg cataaagcta cctagaaact catggtaacg
     4441 tttatagctg ataccatttt ggtccgcata ggcaatttcg acgttgttat ctggacgaaa
     4501 ggcatttcca gcgataattt ccatatcacc gtctagattc ttttcatcaa aaggaagaat
     4561 ggtaattcct gcctgctcaa gaccgcgttg ggtaaagtag tacttttcaa catctgatcc
     4621 ctgaaccttg tgccccatct ggtgcaacat caaggccaag gcactcatcc ctgatccctt
     4681 aattccgata aaatgatatg tctttgacat gttttctccc ctattctgtc attctggtca
     4741 gattcaactc ttgggcaacc cgacgttctt gttctgtttg tttacttttt ttattgtaga
     4801 tttggctctt ctttagaaaa tcataattgt ttttctttgg agcaggtgct gacacttctt
     4861 cattcttggt agggatagaa tgaacttctt ccgccaagat ataatgagac tgggtcaatt
     4921 tttggctata tttgacaaat tcaccaggat tttccttttg gaaaggagtt gtcggttgat
     4981 tgccctgtct aactagactg ggctgagaat gacgtctcgc aaggctgaaa tcctgagtta
     5041 gatagttagc agagcgtttc tttttcaagt ctgcacgcgc ttcttcacgc gccacctccg
     5101 catagctctt tccttctttt ttaaccccta aaggagcttt tttaggtttc cctacttgct
     5161 tttcaatcgg ttttactggt ttttcttcag caataggagc ccattctaaa taatttttat
     5221 ctcgatactc acccttgata ttactgatca gatcagactc atcatagaga ttcatgactg
     5281 gcatttcagt caacatgacc tcgtcatctg acaccaatgg aaatcgttct tgtttcattt
     5341 tctatttcct ttcaacactt cattatagcg tattgtcttg atttttcaag tgctggcttc
     5401 agaaattccc aaaatttctc taatttctgc tagggtcaga ctaccacgtg actctgtgcc
     5461 gtccaatact tgtgacacca gatgtttctt ttgttcttgg agttcctgaa ttttttcttc
     5521 aatggttccc ttggtcacca agcgatagac ctcaaccgtt tcttcctgac ccatccgatg
     5581 ggcacggcca atggcttgcg cttccaccgc aggattccac caaaggtcaa ccaagatcac
     5641 tgtatctgca cctgacaggt tcagaccgac cccaccagcc ttgagggaaa tcagaaaggc
     5701 atctctttct ccttgattaa aggccttggt catgtcttgt ctttccttgg ctggggttga
     5761 acccgtaatt ttaaaggaag tcaggcccaa gtctgacagt tcttgttcaa ttttttccaa
     5821 cattcccttg aactgagaga aaatcaagac acggtgtccg ccgtctgcca cctgtaccag
     5881 taggtctcgg agactatcta gtttgccgct ggctccctga taatcttcca taaacagggc
     5941 aggagtgtca catatttgac gcaagcgcat caaaccagat aaaatttcca cacgacttcg
     6001 ctgaaattcc tgttctgaca cttgagccag atggtctcgc atctgttgta actgggcaag
     6061 gtaaatagcc ttttgctggt cttccagttc atttttataa accacctcaa tcaagtctgg
     6121 caattcagtc agaacttctt ctttcttgcg tcgcatcacg aaaggcttga taaactgagc
     6181 cactcgctct gctggcaatt tcataaattc tttcttgctt ggcaaaagtc cgggcatgac
     6241 gatttggaaa atagaccaca actcacccag atggttttca atcggagttc ctgacaaggc
     6301 aaagaccgac ggcaccacaa attgtctcaa ggtctgggca atcttggtct gggcattttt
     6361 catgacctga gcctcatcta agaaaaggaa gtcaaaggcc atcccctgat aaaactcact
     6421 gtcctgacgg aaggtggcat agctagtcac atagatttga tggctctcgg caagaatctc
     6481 ctcacgactt gctttcaaac catgaacaac agccacatcc aactgtgggg caaatttctg
     6541 aaactcatcc gcccagttgt aaatcaaacc cgacggagcg agaatcaaga ctcgactttc
     6601 ttttgtcact tgactagtca aaaaagcaat ggtctgaagg gttttcccaa gtcccatatc
     6661 atcagccaaa atcccaccaa aaccataatg atggagcatc tgcaaccagc caattccctt
     6721 ttcctgataa tctcgcaagt cagccttgac ctgagttgct tgcaaaggaa agtcctctgg
     6781 atgcgtcaaa tcctgggcca gattctggaa ttcttgtgaa aaagaaacac ggtctcgccc
     6841 ttcaaagaga tgagctaaac tgtaggccaa ggatttccga gcctgcaagg tcccatcttt
     6901 taattcaaat tgccccagtt cctgtagatt ttggcgaatt ttcttggttt cttcatcgaa
     6961 aaagtaaact tgattagacg aatcaatata aaaatcctga ttggcaacca aggcctgcat
     7021 ggcttggtcg atttcctcct gggcaatatt ttgaaaatca aactggattt ccaagagacc
     7081 tcccttggag gcaatctgca cctgaggact cgctaggcta taaagctctt ctagtttatc
     7141 tgataggtca acatgcccga gtttttcaaa gactggaatg atatcatgaa aaaaatgata
     7201 gacagactcc gcttttaagg cctgacgcca agattgaaaa tcggcttcaa agcccgcagc
     7261 caaacagact tggaaaattc tttcttctaa gtccgcgtca cttgaaaatg gtaattcttc
     7321 tagctcttgt cggctagata cctgtctatt tccataatca aactgaattt ctaaacgaat
     7381 ccgattatct tcttccctgt caaagtaaaa agagggcgca aaagttttga tttgtagacg
     7441 ttctggagct gaaacggtgc ccatctggat aaaaagagtc agacaggagg ccaatttgtc
     7501 tcgatcactg ctatcaaatt gcaggtattt ctttccttgt tgacccacag gtaacgcttt
     7561 aatttccttg agaagacgca tctgctggtc tgttaaaaaa taaacctgac ctttatggaa
     7621 aagtactgct ccctgataaa agacattgac cctaggactc tcactgattt ccatttcaaa
     7681 atagtccgag tattctgtta ctgtaaaggc aaatagattg gcatcagcat gcatatcctg
     7741 aaaaagcagg gtttggtagc tatccacttg atggtcaaat tgaaaatggg gcaaggccat
     7801 cagtaaattc acaccctgct caaaaaaggt cagagggaaa aagaggtgcc gaccttggtt
     7861 ttggaaaaag aggtctggaa ccagcccttc ctccgttagt ccgtgcaaga aagtcaaaag
     7921 ttcttggctg gcatcatcaa aggcttccca agaaagagac tcctcataaa tcttgccaat
     7981 catatacgac tttctctgct cgacaatcct taaaaaaagt ggaatatccc gaatgacata
     8041 gtatttttgg ctattgattt ggccgattct cagagtccac aagatatgat tggttcctgc
     8101 ttccacctga cccacagctg ataactcata ggcgcattct gattttggag ataaaattcg
     8161 attcaaaaac ttgccaccca aggtcacctt ggtttcaacg gcctcttttt cttcatgacc
     8221 ttcttccaga ctccacaaga tttcctgacc acgctcatca tttttcagaa aatgctctag
     8281 cgctgccaaa tgcacacagt agcccctctt ttgaaaagaa tcacaggcac aaaaaaccaa
     8341 atcatcctct aaactatagc gcagttcttc ttctgcaacg cgagcgtaga gccgattgtt
     8401 cttttccttg atgatatcaa ccttaccagt ttcataaagg gcaacacctt cgatacgaat
     8461 tttccccgga atcaatttag ccatattttc acctttacct tatcttttta ttataccata
     8521 ttttcgccta tgaaaatagc cttctaggaa gacttttctc ctagaaggct ggatttttaa
     8581 cgtttggcaa aagtagccac aatccgctga cagacttctt gcaacagaga tttgggcata
     8641 gctatattga tgcgggcatg gagacttcct tcctctccaa aatccaaacc acggttgagg
     8701 ataaccttgg cttcatttct caacaactct tgcaatgttt catcagtcag gtcataggct
     8761 gaaaagtcaa gccaaatcaa gtaggtacct tgcggtttca tgaccttgat tttagtctct
     8821 tttccaaata gatccaccac ataattgatg tggtcttcaa agacttgctt gagttcctct
     8881 agccaatctt taccgtatcg ataggcagct tctgtcgcca aataacccaa gcctgaaatt
     8941 tcatgctgat tattggccaa caggcgtttc tggaaagcca gtctcaactt aggattttca
     9001 atgactgcat aggaattttt tgttccagca atattaaatg ttttagtggc actgctcaag
     9061 acgatagcaa aatttttgaa ggcaggattg atggtattga aagactggtg tttgtgacca
     9121 aagagggtca aatcttggtg aatctcatcc gaaactaaca aaacaccgtg tttttggcaa
     9181 agttggccaa tcttctccaa cacttctttt tcccaaacac gtccaccagg attgtgaggg
     9241 ttgcaaagaa tatagagttt aacctcctct tccaccaaat ccttttcaag ttggtcaaag
     9301 tcaatctcaa acagaccatc cttttccact aaggaattag taatcaatct acgattattc
     9361 aacttgacac tgcgagcaaa gggtgggtag acaggcgtgt taattaaaac cgcctcgcct
     9421 tcttttgtaa aggtttgaat agctgttgag atggctggta ccacaccctc gataaagaca
     9481 agagcctctt tgtcaaagtt gtaaccgtat tgtgtagctt cccacttttg aatttcctta
     9541 attaagtctt cactggcata ggtataacca taaaccagtt ggtctgcgta agtttgcacg
     9601 gcttggcgga tttcaggcaa gaccacaaag tccatatccg ctatccaagc tggtagaact
     9661 tcactatccg tttctgtttc tttccattta taggtatggt gccctaaacg gttgggcagg
     9721 cttgtaaaat catattttcc catctttgtc ttatccttct aaggcttggc gcaaatctgc
     9781 aatcaaatct ctagcatcct caatcccaat agacaaacgc aagaggtcat ctgtcaaacc
     9841 ataagaatgg cgtacttctg ctggaatatc agcatgagtt tgagtcgttg gataagtaat
     9901 aagactttcc actccgccca aactttccgc aaaagagaag accttgagac tgttcaaaat
     9961 atgaggaatg cgtgtttcat cggctacttt aaaggaaatc atgcctccac gaccagtgta
    10021 gagaacttcc ttaactgctg gagaatcctt caaaaaggca accacttctt gggcgttagc
    10081 tgttgagcgc tccatacgaa gagataaggt cttgagacca cgaagcaact ggtagctgtc
    10141 aaatggagac aagactgccc ctgttgtatt gagattgtaa aaaagcttct cgtatagttc
    10201 taaactattg gtcacaacca ctccagccaa gacatcattg tggcctgcta gatacttggt
    10261 tgctgaatgg agaacgatat ctgctccatc ttcaatcgga cgttggtaga tagggctata
    10321 gaaggtattg tccaccacca ctttggcacc cttagcatga gccaattttg ctagtttttc
    10381 gatatcaaat tccaacatca agggattggt tggggtttcg atatagagaa catccacatc
    10441 cttttctaac tcggcaatca actcttcttc tgtattggca taggtaaaat ggaaacgacc
    10501 ttcctgctcc acttggttaa accagcgaaa agaaccaccg taaagatcac gcactgccaa
    10561 gaccttactt cctactggaa agacgctaaa ggccagtaca atagctgaca tccctgagct
    10621 agtcgctagg gcatagtctg ctgactcaat agccgccaag acttcctcag ccttactacg
    10681 agttggattt ttagtgcgcg tatagtcaaa cccagtagat cgaccaaact ctggatgctg
    10741 ataggtcgtt gaaaaatgaa gcggtgtcac caatgcacct gtcgcttcat ctgacttaat
    10801 acccgcctgg gccaaaattg tgttaatgtg taattccttg ctcatacaat acctccaaat
    10861 ctatagtaac tattgtacca cttattttca tcaactcatt ttcttctttt caagagctag
    10921 ttatagtttc aaactatata aaaagggagt ttttcctgct ccctttaata gactataaaa
    10981 tggtgaatct caaaagacac cttcactcta tcatttgctc ctgcacaaaa cgagcataac
    11041 gctcatgatt ttccagtagt tccttatgag ttcctgagcc agtgattttc ccctcctcta
    11101 agaagaaaat acaatccaca tcttttaccg ttgacaaacg atgcgctata atcacaaccg
    11161 tcttctcctt taatacagaa tagaggctac tgataatcgc atactcagaa tccgcatcaa
    11221 gattagcagt ggcttcatca aatataagaa tttcagcatc ttttaagtag gctctagcta
    11281 tttgaagtct ttggctttgc ccccctgaca agagtcgtcc gcgttcacca acttcagtat
    11341 ctagtccctc tttcatggag cgaatctcat cacctagtga tactaagtct agcactttca
    11401 tcaattcatc atcagttact aagcgattca aaccgagaca aagattgtca cgaatactgc
    11461 cagataagac tgcattattt tgtgaaaccc aagcgatttt acttctccat tcttttaagt
    11521 taaaatcata tatacttgat tgctccatta gaatatctcc tgaaagcggt ttataaaacc
    11581 gctctaacaa acgcacaatc gttgattttc ctgatccaga tggtccaaca aaagcaattt
    11641 tttgcccctt gaaaattgaa caagtaatat cctttaagac aggtcgattt tcatcataac
    11701 caaaatagac atggtt
//
LOCUS       DAVBOD010000060        11692 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 640-05
            SAMEA1012484-rid20186543.denovo.060, whole genome shotgun sequence.
ACCESSION   DAVBOD010000060 DAVBOD010000000
VERSION     DAVBOD010000060.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012484
            Sequence Read Archive: ERR059358
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11692)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11692)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979948.1
            Genome Coverage       :: 595x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:03:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,266
            CDSs (total)                      :: 2,219
            Genes (coding)                    :: 2,091
            CDSs (with protein)               :: 2,091
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 71 of 128
            Pseudo Genes (incomplete)         :: 50 of 128
            Pseudo Genes (internal stop)      :: 33 of 128
            Pseudo Genes (multiple problems)  :: 22 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11692
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012484-rid20186543.denovo.060"
                     /strain="NIG 640-05"
                     /db_xref="taxon:1313"
     gene            complement(1..162)
                     /locus_tag="VQ862_001772"
                     /pseudo
     CDS             complement(1..162)
                     /locus_tag="VQ862_001772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5/IS1182 family transposase"
     gene            148..633
                     /locus_tag="VQ862_001773"
     CDS             148..633
                     /locus_tag="VQ862_001773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001855144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HET3116075.1"
                     /translation="MAPTDKEDLIRTLELAPHVEGGYFRQTKKASDTINLAGKGRALY
                     TSIYFLLEETNPSHFHRLTADEIWYFHAESPLTVHMITADGHYEAVTLGLDISKGQQL
                     HYCVPKGTIWGSTVDKDDALVSCLVAPGFEFEDFELFERVDLLATYPEHKEMIERLTR
                     Y"
     gene            717..1424
                     /locus_tag="VQ862_001774"
     CDS             717..1424
                     /locus_tag="VQ862_001774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET3116076.1"
                     /translation="MTKQVLLVDDEEHILKLLDYHLSKEGFSTQLVTNGRKALALAET
                     EPFDFILLDIMLPQLDGIEVCKRLRAKGVKTPIMMVSAKSDEFDKVLALELGADDYLT
                     KPFSPRELLARVKAVLRRTKGKQEGDDSDNIADNSWLFGTLKVYPERHEVYKANKLLS
                     LTPKEFELLLYLMKHPNMTLTRERLLERIWGYDFGQETRLVDVHIGKLREKIEDNPKA
                     PQFIRTIRGYGYKFKEL"
     gene            1425..2756
                     /locus_tag="VQ862_001775"
     CDS             1425..2756
                     /locus_tag="VQ862_001775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000833277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component sensor histidine kinase"
                     /protein_id="HET3116077.1"
                     /translation="MKRYLQFWLVNLSVSLILIAGMALTWISKGIGLFLLALSLGLGG
                     YWLFCLWKWEVAFETLHQPLLTSSEYFLEKGQEDLKSLAQYVSGLKTKVSQQDQQYKD
                     LAETMEVLLSHLTMGTFLVSAQGQMLLSSRSLPHYFPDVDGDISSLDDLKRMDIRNLV
                     HQAFDQKTRLKQEVSGFHEGDLILEVTAVPVFSPTQSVEAVLVLLYDLTTIRTYEKLN
                     LAFVSNASHELRTPVTSIKGFAETIKGMSAEEEALKDDFLDIIYKESLRLEHIVEHLL
                     TLSKAQQMPIQWTTLSLAEFVQDLTQSLQPQLKKKDLQLKVQVPDDVTLVSDSQLLSQ
                     ILLNLLSNAIRYTEQGGKIEVKTQKVNEGIKISVSDTGIGISQLEQDRIFERFYRVNK
                     GRSRQTGGTGLGLAIVKELSQLLGGQVTVTSQLGRGSCFTIFLPNQSFAQD"
     gene            2923..3798
                     /locus_tag="VQ862_001776"
     CDS             2923..3798
                     /locus_tag="VQ862_001776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000669496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate-binding protein"
                     /protein_id="HET3116078.1"
                     /translation="MKFKKILTLAAIGLSGFGLVACGNQSSTSKQSASGTIEVISREN
                     GSGTRGAFTEITGILKKDGDKKIDNTAKTAVIQNSTEGVLSAVQGNANAIGYISLGSL
                     TKSVKALEIDGVKASRDTVLDGEYPLQRPFNIVWSSNLSKLGQDFISFIHSKQGQQVV
                     TDNKFIEAKTETTEYTSQHLSGKLSVVGSTSVSSLMEKLAEAYKKENPEVTIDITSNG
                     SSAGITAVKEKTADIGMVSRELTPEEGKSLTHDAIALDGIAVVVNNDNKASQVSMAEL
                     ADVFSGKLTTWDKIK"
     gene            3916..4779
                     /gene="pstC"
                     /locus_tag="VQ862_001777"
     CDS             3916..4779
                     /gene="pstC"
                     /locus_tag="VQ862_001777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000595184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HET3116079.1"
                     /translation="MTKQAFKEAVFRAIFFMSATVAVVAILLICFFIFSNGLPFMANY
                     GFARFLLGSDWSPTNIPASYGILPMIVGSLLITLGAIVIGVPTGILTSVFMVYYCPKP
                     VYGFLKSAINLMAAIPSIVYGFFGLQLLVPWIRTFLGNGMSVLTASLLLGIMILPTII
                     SLSESAIRTVPKTYYSGSLALGASHERSIFSVILPAARSGILSAVILGIGRAVGETMA
                     VILVAGNQPIIPSGLFSGTRTLTTNIVLEMAYASGQHREALIATSAVLFFLILLINAY
                     FAYLKGKSSYE"
     gene            4772..5587
                     /gene="pstA"
                     /locus_tag="VQ862_001778"
     CDS             4772..5587
                     /gene="pstA"
                     /locus_tag="VQ862_001778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HET3116080.1"
                     /translation="MSKYLLKLLVYCFSALTFGSLFLIIGFILIKGLPHLSLSLFSWT
                     YTSENISLMPAIISTVILVFGALLLALPIGIFAGFYLVEYTKKDSLCVKIMRLASDTL
                     SGIPSIVFGLFGMLFFVVFLGFQYSLLSGILTSVIMVLPVIIRSTEEALLSVSDSMRQ
                     ASYGLGAGKLRTVFRIVLPVAMPGILAGVILAIGRIVGETAALMYTLGTSTNTPSSLM
                     SSGRSLALHMYMLSSEGLHVNEAYATGVILIITVLMINTLSSLLSRKLVKGAS"
     gene            5589..6341
                     /gene="pstB"
                     /locus_tag="VQ862_001779"
     CDS             5589..6341
                     /gene="pstB"
                     /locus_tag="VQ862_001779"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003101281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HET3116081.1"
                     /translation="MGTFSVRHLDLFYGDFQALKNISIQLPERQITALIGPSGCGKST
                     FLKTLNRMNDLVPSCHIEGQVLLDEQDIYSSKFNLNQLRKRVGMVFQQPNPFAMSIYD
                     NVAYGPRTHGIRDKKQLDALVEKSLKGAAIWEEVKDDLKKSAMSLSGGQQQRLCIARA
                     LAVEPDILLMDEPTSALDPISTLKIEDLIQQLKKDYTIIIVTHNMQQASRISDKTAFF
                     LTGEICEFGDTVDVFTNPKDQRTEDYISGRFG"
     gene            6356..7006
                     /gene="phoU"
                     /locus_tag="VQ862_001780"
     CDS             6356..7006
                     /gene="phoU"
                     /locus_tag="VQ862_001780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001245788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HET3116082.1"
                     /translation="MRNQFDLELHELEQSFLGLGQLVLETASKALLALASKDKEMAEL
                     IINKDHAINQGQSAIELTCARLLALQQPQVSDLRFVISIMSSCSDLERMGDHMAGIAK
                     AVLQLKENQLAPDEEQLHQMGKLSLSMLADLLVAFPLHQASKAISIAQKDEQIDQYYY
                     ALSKEIIGLMKDQETSIPNGTQYLYIIGHLERFADYIANICERLVYLETGELVDLN"
     gene            7082..7507
                     /locus_tag="VQ862_001781"
     CDS             7082..7507
                     /locus_tag="VQ862_001781"
                     /inference="COORDINATES: protein motif:HMM:NF025080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET3116083.1"
                     /translation="MTNLSSVDSEELFQFYREQRNAENFIKERKAGFFGDKTDSSTMI
                     KNEVRMMMGCLAYNLYLFLKQLAGDEVKVLTIKRFRRLFLHIAGKYVSTARRHILKFS
                     SLYAYSKQFQALFDTICQINLILPVPYKARGQGKTCLTE"
     gene            complement(7681..8061)
                     /locus_tag="VQ862_001782"
     CDS             complement(7681..8061)
                     /locus_tag="VQ862_001782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HET3116084.1"
                     /translation="MREFGEKIKRLRLAKKISRSEFCGDESELSIRQLIRIENGESRP
                     TLTKLKYIAERLGGEDYKLMPSYIELDKECLELKYFLMRTPTYEDETIAQKKESVLIR
                     FLKSIMIGYLRKKDLSSQIIHIWH"
     gene            8273..9289
                     /locus_tag="VQ862_001783"
     CDS             8273..9289
                     /locus_tag="VQ862_001783"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000415108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HET3116085.1"
                     /translation="MEKQTVAVLGPGSWGTALSQVLNDNGHEVRIWGNLPEQINEINT
                     HHTNKHYFKDVVLDENIIAYTDLAETLKDVDAILFVVPTKVTRLVAQQVAQTLDHKVI
                     IMHASKGLEPDSHKRLSTILEEEIPEHLRSDIVVVSGPSHAEETIVRDLTLITAASKD
                     LQTAQYVQELFSNHYFRLYTNTDVIGVETAGALKNIIAVGAGALHGLGFGDNAKAAII
                     ARGLAEITRLGVALGASPLTYSGLSGVGDLIVTGTSIHSRNWRAGDALGRGESLADIE
                     ANMGMVIEGISTTRAAYELAQELGVYMPITQAIYQVIYHGTNIKDAIYDIMNNEFKAE
                     NEWS"
     gene            9311..10210
                     /gene="galU"
                     /locus_tag="VQ862_001784"
     CDS             9311..10210
                     /gene="galU"
                     /locus_tag="VQ862_001784"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000202216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HET3116086.1"
                     /translation="MTSKVRKAVIPAAGLGTRFLPATKALAKEMLPIVDKPTIQFIVE
                     EALKSGIEDILVVTGKSKRSIEDHFDSNFELEYNLKEKGKTDLLKLVDETTGMRLHFI
                     RQTHPRGLGDAVLQAKAFVGNEPFVVMLGDDLMDITDEKAVPLTKQLMDDYERTHAST
                     IAVMPVPHDEVSAYGVIAPQGEGKDGLYSVETFVEKPAPEDAPSDLAIIGRYLLTPEI
                     FEILEKQAPGAGNEIQLTDAIDTLNKTQRVFAREFKGARYDVGDKFGFMKTSIDYALK
                     HPQVKDDLKNYLIQLGKELTEKE"
     gene            10628..11560
                     /locus_tag="VQ862_001785"
     CDS             10628..11560
                     /locus_tag="VQ862_001785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000428165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3116087.1"
                     /translation="MENKFVEFIENNKKVIISSVAVGVVLILGFGWYSYNQQQAEQQA
                     KIVQLEKDSKSDKEQVDKLFESFDASSDESISKLKELSETSLKTDAGKDYLNNKVKES
                     SKAIVDFHLQKGLAYDVKDSDEKFKDKATLETNVKEITKQIDFIKKVDETFKQENLEE
                     TLKSLNDLVDKYQKQIELLKKEEEKAAEKAKESSSQSNSSGSASNESYNGSSNSNVDY
                     SSSEQTNGYSNNYGGQDYSGSGNSSTNGGSSEQYSSRNSNIGANNGYTEYRSIDASGH
                     VRDTYHNRSNGDVFDENGNYLGNLGGGIAEPPQR"
BASE COUNT         3631 a         2239 c         2294 g         3528 t
ORIGIN      
        1 catttctttt taccagaatc attcgctaat tcttctttta gggcgattga tttgtacttc
       61 cgtcgcatca atcattaccg tgtcctcaga actgagagga gttcttgaaa tcgtaaaacc
      121 actttgaaca agagttactt caacccattg gctccgacgg ataaagaaga cttgataaga
      181 actctagagt tagctcccca tgttgaaggt ggctatttta gacaaacaaa aaaagcttca
      241 gacactataa accttgctgg taagggaagg gcgctttata ccagtattta tttcttatta
      301 gaagaaacga atccttcaca ttttcaccga ttgacagcag atgaaatctg gtattttcat
      361 gcagaatccc cacttactgt tcacatgatt acagcagatg gtcactacga agcagtcact
      421 ttaggcctgg acatatccaa agggcaacaa cttcactact gtgttcctaa gggcactatt
      481 tggggatcaa cagttgataa ggatgatgct ctggtttctt gtcttgttgc tcctggtttt
      541 gaatttgagg attttgaatt atttgaaagg gtagatctac tggcgaccta tccagagcac
      601 aaggagatga ttgagcgttt gaccagatac tagtctttat aagcaaattt aatctgattt
      661 agcaatgtta ggatttctga taattgtgtt ataatgttac caataggaga taatagatga
      721 caaaacaagt cttattagtg gatgatgaag aacacattct gaaattgctt gactaccatt
      781 taagtaagga aggcttttct actcaattgg taacaaatgg acggaaggcc ttagctttgg
      841 cagaaacaga accctttgat tttatcttgc ttgatatcat gttaccacaa ttagatggca
      901 tagaagtttg taagcggctg agagccaaag gcgtcaaaac tccaattatg atggtttctg
      961 cgaaaagtga tgaatttgat aaggttttgg ccttggaatt aggggctgat gactacctga
     1021 ccaagccttt tagccctaga gaattactgg cgcgtgtcaa ggctgtcctc aggcgaacta
     1081 aaggaaaaca agaaggagat gattcagata atatcgctga caattcttgg ctatttggga
     1141 ccttgaaagt ataccctgag cgtcatgaag tctacaaggc gaataagtta ctgagtttga
     1201 ccccaaaaga atttgaactc ttgctctatc ttatgaaaca tcccaacatg acactgacta
     1261 gagagcgtct tttggaacgt atctgggggt atgactttgg gcaggaaaca cgtttggtgg
     1321 acgttcatat tggtaagttg agggaaaaaa ttgaagacaa tcctaaagcc cctcaattta
     1381 ttcgaaccat tcggggttat ggttataagt tcaaggagtt atagatgaaa cgctaccttc
     1441 aattttggct agtcaatcta agtgttagcc tcattctgat tgcagggatg gcattaactt
     1501 ggatcagtaa aggcatcggt ctctttcttc tagccctttc tttgggacta ggtggctact
     1561 ggctcttttg cctttggaaa tgggaagttg cttttgagac cttgcaccaa cctctcttga
     1621 ccagtagtga atacttttta gaaaaagggc aagaagactt aaagtctttg gctcagtatg
     1681 tgtctggcct aaaaaccaaa gtctcccaac aggatcagca atacaaggac ctagccgaaa
     1741 caatggaggt tcttctgtcg cacctaacca tggggacgtt tttagtttcc gctcaaggtc
     1801 agatgttatt atccagtcgc tctctgcctc attattttcc cgatgtggac ggcgacataa
     1861 gttcacttga tgacctcaaa cggatggata ttcggaattt agttcaccaa gcctttgatc
     1921 aaaaaacaag gttaaaacaa gaagtaagtg ggtttcatga gggtgacttg attttagaag
     1981 tgacagcagt tcccgttttt agccccaccc aatctgtgga agctgtgctc gtcttgctat
     2041 atgatttaac aacgattaga acttatgaaa agttaaattt agcctttgtc tcaaatgcct
     2101 cccatgaatt gaggacacca gttacttcga ttaagggctt tgctgaaacc attaagggga
     2161 tgtcagctga agaagaagcg ctcaaggatg actttctaga cattatttac aaagaaagct
     2221 tgcgtcttga gcatattgtt gagcatcttc ttaccttatc taaggctcaa caaatgccta
     2281 tacaatggac gaccctttct ttggcagaat ttgtacagga tttgactcaa agcttgcaac
     2341 ctcagctcaa gaagaaggat ttacagctaa aggtgcaggt gccagatgat gtcaccctcg
     2401 tatcagatag tcaattactt tcccaaatct tactcaatct tttatccaat gccatccgtt
     2461 acactgaaca agggggaaaa attgaggtca agacccaaaa ggtgaacgaa ggcattaaga
     2521 tttctgtatc agatacaggg attggtatta gtcaattaga gcaggatcgt atttttgaac
     2581 gtttttaccg agttaataaa ggtcgaagca gacaaactgg tggcactggt cttggccttg
     2641 ccattgtcaa agaactcagt caattattag gtggccaagt cacggtgacg agtcagcttg
     2701 gcagaggcag ttgcttcacg atttttcttc ctaaccaatc tttcgcacag gactaataat
     2761 ttttaaagct atttttagga gcagccattt ttcaaaagtg gctttttttg attctttaca
     2821 caatctttac atgaatcagg gataaacctt tacaaagact tgttagacta taaatgtagt
     2881 aagcctacac aagaaaaata catagagata aaggtgatta ttatgaaatt caaaaaaata
     2941 cttactcttg cagccattgg cttatcagga tttgggcttg ttgcctgtgg caatcagtca
     3001 tctacttcca aacagtcagc ttcaggaacg attgaggtga tttcacgaga aaatggctct
     3061 gggacacggg gtgccttcac agaaatcaca gggattctca aaaaagacgg tgataaaaaa
     3121 attgacaaca ctgccaaaac agctgtgatt caaaatagta cagaaggtgt tctctcagca
     3181 gttcaaggga atgctaatgc tatcggctac atctccttgg gatctttaac gaaatctgtc
     3241 aaggctttag agattgatgg tgtcaaggct agtcgagaca cagttttaga tggtgaatac
     3301 cctcttcaac gtcccttcaa cattgtttgg tcttctaatc tttccaagct aggtcaagat
     3361 tttatcagct ttatccactc caaacaaggt caacaagtgg tcacagataa taaatttatt
     3421 gaagctaaaa ctgaaaccac agaatataca agccaacact tatcaggcaa gttgtctgtt
     3481 gtaggttcca cttcagtatc ttctttaatg gaaaaattag cagaagctta taaaaaagaa
     3541 aatccagaag ttacgattga tattacctct aatgggtctt cagcaggtat taccgctgtt
     3601 aaggagaaaa ccgctgatat tggtatggtt tctagggaat taactcctga agaaggtaag
     3661 agtctcaccc atgatgctat tgctttagac ggtattgctg ttgtggtcaa taatgacaat
     3721 aaggcaagcc aagtcagtat ggctgaactt gcagacgttt ttagtggcaa attaaccacc
     3781 tgggacaaga ttaaataaaa tgtttgctcc ataaatctct aaagagatgc agacgtttca
     3841 tcgtacaata agataaagaa ggcaagtagg gaggtgtcgt atctccctta ctttcttcac
     3901 tagaaaggac aagatgtgac aaaacaagcc ttcaaagaag cagtttttag ggcaattttt
     3961 ttcatgagtg caacagtagc tgttgtagct attttgctaa tctgtttctt tatttttagt
     4021 aatggcttac ctttcatggc taactacggc tttgcccgtt ttttattagg cagtgattgg
     4081 tcgccaacga acattccggc aagctatggt attttaccaa tgatcgttgg ttccttatta
     4141 attaccttag gagcgattgt gattggggtg ccaacaggca tcttgacatc ggtgtttatg
     4201 gtttattatt gtccaaagcc cgtctatggc ttcttaaaat cagctatcaa cttgatggca
     4261 gccattccat ctattgttta tggttttttc ggcctacaat tattggtgcc ttggattaga
     4321 acctttttag gaaatggcat gagtgtccta accgcttcgt tactattagg aataatgatt
     4381 ttgccaacca ttatcagttt gtcagaatct gctatccgaa cagttcccaa aacgtattat
     4441 tctggtagct tggctctagg agctagtcat gaacggagta tttttagtgt catcttgcca
     4501 gctgcgagat ctggtatttt atcagcagtt attttaggaa tcggtcgcgc agtaggtgaa
     4561 accatggcag ttattttggt ggcaggcaac cagccaatta ttccaagtgg actcttttca
     4621 ggaaccagaa ccttaacaac caatattgtt ctggaaatgg cttacgcatc aggtcagcat
     4681 agggaagccc ttattgcaac ctcagcagtt ctctttttcc ttattctctt gattaatgcc
     4741 tactttgcct acttgaaagg aaaatcatct tatgagtaaa tacctgctaa aacttctcgt
     4801 ttattgtttt tcagctttaa cctttggctc tctcttttta atcattggtt ttatcctcat
     4861 caaaggctta cctcatctaa gtctatccct cttttcttgg acttatactt ctgagaacat
     4921 ttcccttatg ccagcgatta tttccaccgt tattctggtt tttggtgctc ttcttttagc
     4981 tttgcccata gggatttttg ctggttttta tcttgtggaa tatacaaaaa aagattccct
     5041 ttgtgttaaa atcatgcgat tggcctcaga taccttgtct gggattcctt ccattgtttt
     5101 tggtctgttt ggcatgctct tctttgtagt cttcttaggt tttcaatact ctctgttatc
     5161 aggaatctta acctcagtta tcatggtgtt gccagtcatt attcgctcaa cagaagaagc
     5221 ccttttatct gttagtgata gcatgcgtca agcaagttat ggacttgggg caggtaagtt
     5281 acggactgtt tttagaattg ttctaccagt tgccatgcca ggtattttag ctggagtgat
     5341 actagctatt ggccgtatcg ttggtgaaac agctgccctc atgtatacat taggtacctc
     5401 taccaatacg ccaagtagtc tcatgtcttc aggccgttct ctagccctac atatgtatat
     5461 gctgtcaagt gaggggctac atgtcaatga agcctatgct accggcgtga ttttaattat
     5521 tactgtttta atgataaata ctctatcaag cttattatct cggaaacttg tgaaaggagc
     5581 ttcctagtat gggaacattt tcagtcagac acctagactt attttacggg gattttcaag
     5641 ccttaaaaaa tatttcgatt caattaccag aaagacagat tactgccttg ataggcccat
     5701 ctggttgtgg caaatcaact tttctaaaaa cccttaaccg gatgaacgat ttggttcctt
     5761 cttgccatat tgaaggccaa gtcctcttag atgagcaaga tatttatagt agcaaattca
     5821 accttaatca gctacgtaag cgtgtaggga tggtttttca acagcctaat ccctttgcca
     5881 tgtctatcta tgataacgtg gcttatggcc caaggacaca tggtattcga gacaaaaaac
     5941 aattagatgc cttagtggag aaatctttaa aaggggcagc catttgggaa gaagtcaaag
     6001 atgatcttaa aaagagtgcc atgtccttat ctggcggtca gcagcaacgc ctttgcattg
     6061 cgcgagcttt agcagtagaa cctgatattc tgttaatgga tgagccgact tcagccttag
     6121 accctatctc cactttaaaa attgaagacc tcattcagca actaaaaaaa gattatacga
     6181 ttatcattgt tacccataac atgcaacaag cttcacgtat ttcagataaa actgcttttt
     6241 tcttaacagg agaaatttgc gaatttggag ataccgttga cgtgtttacc aatccaaaag
     6301 atcagcgcac agaagactat atttcaggac ggttcggata aggaaggaaa aacctatgag
     6361 aaatcaattt gacttagaat tgcatgaatt agaacaatcc tttttaggac tagggcaact
     6421 tgtccttgaa acagcttcaa aagccttact ggccttagcc tccaaagaca aggagatggc
     6481 agagctaatt atcaataagg atcatgctat caaccaaggt caaagcgcta tcgaattgac
     6541 ctgtgcccgt ttgttggcct tgcagcagcc acaagtgtct gaccttcgat ttgtgattag
     6601 catcatgtct tcttgttcag accttgaacg tatgggagac catatggcag gcattgccaa
     6661 agctgttttg caactaaaag aaaatcaact agcccctgac gaagaacagt tacaccaaat
     6721 gggtaaatta tccctcagca tgctagccga tttattggtt gcctttcctt tgcaccaagc
     6781 ctcaaaagct attagtattg ctcaaaaaga tgaacagatt gaccaatatt attatgcctt
     6841 atcaaaggaa atcattggac ttatgaaaga ccaagaaacc tcaattccca atggaacaca
     6901 atacctttat atcatagggc atctggaacg cttcgctgat tacattgcta acatttgtga
     6961 acgcctagtc tacctagaaa caggagaact agtggatttg aattaattca actaatcctt
     7021 taatccttaa aagagaagag tacgattaag tgctcttttt tatggttgta aaaaagttca
     7081 tttgaccaat ttaagcagtg tagatagtga ggagctgttt caattctatc gtgaacaaag
     7141 gaatgctgaa aactttatca aagaaaggaa agcaggattc tttggggata agacagatag
     7201 ttcgaccatg attaagaatg aagtacgtat gatgatgggc tgtctggctt ataatctcta
     7261 cctcttttta aagcagctag ctggtgatga agtaaaggtc ttgactatca agcgttttcg
     7321 acgtctcttc cttcatattg ccggaaaata tgtctctact gctagacgac atattctcaa
     7381 attctcaagt ctatacgcct attcaaaaca gtttcaagcc ttatttgata caatctgcca
     7441 gataaatctg atactccctg ttccatataa agctagaggg caggggaaaa catgcctaac
     7501 agaataagtc accttatttt aaaaatcgag catcaaacca agagaggagt ctgccctttt
     7561 ttaggaaaaa atcaagacaa atctcctcaa ttatgtctcg aacatcagaa attaagcaaa
     7621 atcaccagaa ggacagtatt tcaactagct tttctggtaa tttttgaact gtgtagttcg
     7681 ctagtgccag atatgaataa tttgggatga taaatctttc ttcctcaggt agcctatcat
     7741 aatactcttc aaaaatctta tcaaaacact ctctttcttt tgggcgatag tttcatcttc
     7801 gtatgtagga gtcctcatca agaaatactt caattctagg cattccttat ccaactctat
     7861 ataacttggc atcaacttgt aatcttcacc ccccaaacgt tcagcgatat attttaactt
     7921 tgttagtgtt ggtctggatt ctccattttc aattctaatt aattgacgga tacttaattc
     7981 agactcatca ccacaaaatt ctgaacgact gattttttta gccaaacgta atcttttaat
     8041 tttttcgcca aactctcgca acctacaaga acctcctgag ttgtttacct ctatttatag
     8101 catatactga atcaaactat ctatcagatt tcttctcact ttaactaaag actaagagtt
     8161 tatcccttcg tctcggtttt tgtgtatttt tccaccatac cccagtaatg caagtgcaaa
     8221 atcccctaga atatgataga ataagagaaa gaactctatc aaggaggaaa tcatggaaaa
     8281 acaaaccgtc gccgtcttgg ggcctggttc ttggggaacc gccctttcac aagtcttaaa
     8341 tgacaatgga cacgaggtac gtatttgggg aaatcttccc gagcaaatca atgaaattaa
     8401 tacacaccat actaataagc actactttaa agatgtcgtt ctagacgaaa atatcattgc
     8461 ctacaccgac ttagcagaaa cattgaaaga tgtggatgcg attttgtttg ttgtcccaac
     8521 aaaagtgaca cgacttgttg cccagcaagt tgcacaaacc ttggaccata aggttatcat
     8581 catgcacgca tcaaagggat tagaacctga tagccataaa cgattatcaa ccattcttga
     8641 agaagaaatt cctgaacatc tccgtagtga tatcgtcgtt gtttcagggc ctagtcatgc
     8701 agaagagacc attgtgcgtg acctaacttt aataactgct gcttctaaag atttacaaac
     8761 agctcaatac gttcaggagc tatttagtaa tcactacttc cgactttata ccaatacgga
     8821 tgttatcggg gttgaaactg ctggtgctct taaaaatatt attgctgtcg gtgctggagc
     8881 tttacatggt cttggatttg gtgataatgc taaggcagcc atcatcgctc gaggtttagc
     8941 agaaatcacc cgcctagggg tagcactcgg ggccagtcca ttgacctata gcggcttatc
     9001 tggtgtggga gatttgatcg taacgggaac ttccatccac tctcgtaact ggagagctgg
     9061 agatgctctc ggacgaggag aatccctagc tgatatagaa gctaatatgg gcatggtaat
     9121 cgaaggaatt tcaacgactc gagcagccta tgaactagcc caagaacttg gagtctatat
     9181 gcccattaca caggctattt accaagttat ttatcacgga accaatatca aagatgccat
     9241 ttatgacatc atgaacaatg aatttaaagc agaaaatgag tggtcttaac cctctataga
     9301 aaggattttt atgacatcaa aagttagaaa ggcagtcatc cctgctgctg gactaggaac
     9361 tcgattttta ccagcaacca aggcccttgc caaagaaatg ttgccaatcg tagacaaacc
     9421 aactatccag tttatcgtgg aagaagctct caaatcaggt attgaagata ttctagttgt
     9481 cactggtaaa tcaaaacgtt ctattgagga ccactttgat tcaaacttcg aattggaata
     9541 taacctcaaa gaaaaaggga aaacagatct tttgaagcta gttgatgaaa caactggcat
     9601 gcgtctgcat tttatccgcc aaactcatcc acgcggtctc ggagatgctg ttttgcaagc
     9661 caaggctttc gtcggaaatg aaccttttgt cgttatgctt ggtgatgact tgatggatat
     9721 cacagacgaa aaggctgttc cacttaccaa acaactcatg gatgactacg agcgtaccca
     9781 cgcgtctact atcgctgtca tgccagtccc tcatgacgaa gtatctgctt acggggttat
     9841 tgctccgcaa ggcgaaggaa aagatggtct ttacagtgtt gaaacctttg ttgaaaaacc
     9901 agctccagag gacgctccta gcgaccttgc tattatcgga cgctacctcc tcacgcctga
     9961 aatttttgag attctcgaaa agcaagctcc aggtgcagga aatgaaattc agctgacaga
    10021 tgcaatcgac accctcaata aaacacaacg tgtatttgct cgtgagttca aaggggctcg
    10081 ttacgatgtc ggagacaagt ttggcttcat gaaaacatcc atcgactacg ccctcaaaca
    10141 tccacaagtc aaagatgatt tgaagaatta cctcatccaa cttggaaaag aattgactga
    10201 gaaggaataa caaaatcatt tatataaaga ttagccacac ataaattaag taaattctct
    10261 acttgaatct acctatttaa taaaaactaa tgaaaacgct atacttgtat ttgttttttc
    10321 attaaaataa gagtagaata aattagtata gtaaaacaaa aaagcaccga atcggtgcgc
    10381 actttttcaa gttgtgtacg gacaaagcct tattttaact ttgctatgtt gtttctaatg
    10441 gttccaaaat aataaataat tttaaatttg acttaactgt tggagtagtc atggttaaat
    10501 taaatcaacc gagccgaaca taagttgttt aattttgtgg aagctattaa taaaaatata
    10561 ataagggaga aagataggtg taattttaat tttaaagtaa ttgcggacac tatcaaagta
    10621 aaagattatg gagaacaaat ttgtagaatt tatcgaaaac aataaaaaag taatcatttc
    10681 atcagttgca gttggtgttg tattgatatt agggtttgga tggtattcat ataaccaaca
    10741 acaagcagaa caacaagcaa aaattgtaca attagaaaaa gatagcaaat cagacaaaga
    10801 acaagttgat aaactatttg aatcatttga tgcatcttca gatgaatcta tttctaaatt
    10861 aaaagaacta tctgaaactt cacttaaaac cgatgcaggt aaagactatc ttaataacaa
    10921 agtcaaagaa tcatctaaag caattgtaga ttttcatttg caaaaaggtt tggcttatga
    10981 tgttaaagat tctgatgaga agtttaaaga taaagcaact cttgaaacaa atgtgaaaga
    11041 aattacaaaa caaattgatt ttatcaaaaa agttgatgaa acttttaaac aagagaattt
    11101 ggaagaaact cttaaatctc taaatgatct tgttgataaa tatcaaaaac aaatcgaact
    11161 tttgaagaaa gaagaagaaa aagctgctga aaaagcaaag gaatcttcta gtcaaagtaa
    11221 ttcttctggt agtgcttcta atgagtctta taatggatct tccaattcaa atgtagatta
    11281 tagttcatct gaacaaacta atggatattc aaataattat ggcggtcaag attattctgg
    11341 ttctggaaat agttcaacaa atggtggatc atcagaacaa tattcatcta gaaattcaaa
    11401 cattggagca aataatggct atacagaata tagaagcatt gatgctagtg gacatgtaag
    11461 agatacttat cataatcgga gtaatggaga tgtgtttgac gaaaatggga attaccttgg
    11521 aaacttgggg ggcggcattg cagaacctcc acaacgctaa taactatttt agagctgtgt
    11581 tgtttcgaat ggttccaaaa cacattaaaa gctactcatt ttttaagtag cttttttctt
    11641 attcaagttt acatattata ctcaatgaaa atcaaattca aaccacgtca gc
//
LOCUS       DAVBOD010000061        11418 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 640-05
            SAMEA1012484-rid20186543.denovo.061, whole genome shotgun sequence.
ACCESSION   DAVBOD010000061 DAVBOD010000000
VERSION     DAVBOD010000061.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012484
            Sequence Read Archive: ERR059358
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11418)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11418)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979948.1
            Genome Coverage       :: 595x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:03:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,266
            CDSs (total)                      :: 2,219
            Genes (coding)                    :: 2,091
            CDSs (with protein)               :: 2,091
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 71 of 128
            Pseudo Genes (incomplete)         :: 50 of 128
            Pseudo Genes (internal stop)      :: 33 of 128
            Pseudo Genes (multiple problems)  :: 22 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11418
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012484-rid20186543.denovo.061"
                     /strain="NIG 640-05"
                     /db_xref="taxon:1313"
     gene            complement(331..1311)
                     /gene="dusB"
                     /locus_tag="VQ862_001786"
     CDS             complement(331..1311)
                     /gene="dusB"
                     /locus_tag="VQ862_001786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine synthase DusB"
                     /protein_id="HET3116088.1"
                     /translation="MTNLNTPFMIGNIEIPNRTVLAPMAGVTNSAFRTIAKELGAGLV
                     VMEMVSDKGIQYNNEKTLHMLHIDEGENPVSIQLFGSDEDSLARAAEFIQENTKTDIV
                     DINMGCPVNKIVKNEAGAMWLKDPDKIYSIINKVQSVLDIPLTVKMRTGWADPSLAVE
                     NALAAEAAGVSALAMHGRTREQMYTGHADLETLYKVAQALTKIPFIANGDIRTVQEAK
                     QRIEEVGADAVMIGRAAMGNPYLFNQINHYFETGEILPDLTFEDKMKIAYEHLKRLIN
                     LKGENVAVREFRGLAPHYLRGTSGAAKLRGAISQASTLAEIEALLQLEKA"
     gene            complement(1298..2170)
                     /gene="hslO"
                     /locus_tag="VQ862_001787"
     CDS             complement(1298..2170)
                     /gene="hslO"
                     /locus_tag="VQ862_001787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000357853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp33 family molecular chaperone HslO"
                     /protein_id="HET3116089.1"
                     /translation="MDKIIKTISESGAFRAFVLDSTETVRTAQEKHQTQASSTVALGR
                     TLIASQILAANEKGNTKLTVKVLGSSSLGAIITVADTKGNVKGYVQNPGVDIKKTATG
                     EVLVGPFVGNGQFLVITDYGTGNPYNSITPLISGEIGEDLAFYLTESQQTPSAVGLNV
                     LLDEEDKVKVAGGFLVQVLPGAKKEEIARFEKRIQEMPAISTLLESDDHIEALLKAIY
                     GDEAYKRLSEEEIRFQCDCSHERFMNALASLPSSDLQEMKEEDHGAEITCQFCQTTYN
                     FDEKDLEELIRDKS"
     gene            2335..3762
                     /locus_tag="VQ862_001788"
     CDS             2335..3762
                     /locus_tag="VQ862_001788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000280545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HET3116090.1"
                     /translation="MYLGDLMEKAECGQFSILSFLLQESQTTVKAVMEETGFSKATLT
                     KYVTLLNDKALDSGLELTIHSEDENLRLSIGAATKGRDIRSLFLESAVKYQILVYLLY
                     HQQFLAHQLAQELVISEATLGRHLAGLNQILSEFDLSIQNGRWRGPEHQIRYFYFCLF
                     RKVWSSQEWEGHMQKPERKQEIANLEEICGASLSAGQKLDLVLWAHISQQRLRVNACQ
                     FQVIEEKMRGYFDNIFYLRLLRKVPSFFAGQHIPLGVEDGEMMIFFSFLLSHRILPLH
                     TMEYILGFGGQLADLLTQLIQEMKKEELLGDYTEDHVTYELSQLCAQVYLYKGYILQD
                     RYKYQLENRHPYLLMEHDFKETAEEIFHALPAFQQGTDLDKKILWEWLQLIEYMAENG
                     GQHMRIGLDLTSGFLVFSRMAAILKRYLEYNRFITIEAYDPSRHYDLLVTNNPIHKKE
                     QTPVYYLKNDLDMEDLAGIRQLLFT"
     gene            3921..5429
                     /gene="glpK"
                     /locus_tag="VQ862_001789"
     CDS             3921..5429
                     /gene="glpK"
                     /locus_tag="VQ862_001789"
                     /EC_number="2.7.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000076796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol kinase GlpK"
                     /protein_id="HET3116091.1"
                     /translation="MSQEKYIMAIDQGTTSSRAIIFNKKGEKVSSSQKEFTQIFPQAG
                     WVEHNANEIWNSVQSVIAGAFIESGVKPNQIEAIGITNQRETTVVWDKKTGLPIYNAI
                     VWQSRQTAPLAEQLKSQGYVEKFHEKTGLIIDAYFSATKVRWILDHVEGAQERAEKGE
                     LLFGTIDTWLVWKLTDGAAHVTDYSNAARTMLYNIKELKWDDEILEILNIPKAILPEV
                     RSNSEIYGKTAPFHFYGGEVPISGMAGDQQAALFGQLAFEPGMVKNTYGTGSFIIMNT
                     GEEMQLSENNLLTTIGYGINGKVYYALEGSIFIAGSAIQWLRDGLRMVENSPESEKYA
                     RDSHNNDEVYVVPAFTGLGAPYWNQNARGSVFGLTRGTSKEDFIKATLQSIAYQVRDI
                     IDTMQMDTQTAIQVLKVDGGAAMNNFLMQFQADILGIDIARAKNLETTALGAAFLAGL
                     SVGYWKDLDELKLLNETGELFEPSMNESRKEQLYKGWKKAVKATQVFAEIDD"
     gene            5576..7402
                     /gene="glpO"
                     /locus_tag="VQ862_001790"
     CDS             5576..7402
                     /gene="glpO"
                     /locus_tag="VQ862_001790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glycerol-3-phosphate oxidase"
                     /protein_id="HET3116092.1"
                     /translation="MEFSKKTRELSIKKMQERTLDLLIIGGGITGAGVALQAAASGLE
                     TGLIEMQDFAEGTSSRSTKLVHGGLRYLKQFDVEVVSDTVSERAVVQQIAPHIPKPDP
                     MLLPVYDEDGATFSLFRLKVAMDLYDLLAGVSNTPTANKVLSKDQVLERQPNLKKEGL
                     VGGGVYLDFRNNDARLVIENIKRANQDGALIANHVKAEGFLFDESGKITGVVARDLLT
                     DQVFEIKARLVINTTGPWSDKVRNLSNKGTQFSQMRPTKGVHLVVDSSKIKVSQPVYF
                     DTGLGDGRMVFVLPRENKTYFGTTDTDYTGDLEHPKVTQEDVDYLLGIVNNRFPESNI
                     TIDDIESSWAGLRPLIAGNSASDYNGGNNGTISDESFDNLIATVESYLSKEKTREDVE
                     SAVSKLESSTSEKYLDPSAVSRGSSLDRDDNGLLTLAGGKITDYRKMAEGAMERVVDI
                     LKAEFDRSFKLINSKTYPVSGGELNPANVDSEIEAFAQLGVSRGLDSKEAHYLANLYG
                     SNAPKVFALAHSLEQAPGLSLADTLSLHYAMRNELTLSPVDFLLRRTNHMLFMRDSLD
                     SIVEPVLDEMGRFYDWTEEEKATYRADVEAALANNDLAELKN"
     gene            7472..8176
                     /locus_tag="VQ862_001791"
     CDS             7472..8176
                     /locus_tag="VQ862_001791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HET3116093.1"
                     /translation="MMNELFGEFLGTLILILLGNGVVAGVVLPKTKSNSSGWIVITMG
                     WGIAVAVAVFVSGKLSPAHLNPAVTIGVALKGGLPWASVLPYILAQFAGAMLGQILVW
                     LQFKPHYEAEENAGNILATFSTGPAIKDTVSNLISEILGTFVLVLTIFALGLYDFQAG
                     IGTFAVGTLIVGIGLSLGGTTGYALNPARDLGPRIMHSILPIPNKGDGDWSYAWIPVV
                     GPVIGAALAVLVFSLF"
     gene            8473..8676
                     /locus_tag="VQ862_001792"
     CDS             8473..8676
                     /locus_tag="VQ862_001792"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3116094.1"
                     /translation="MPKWSNPDYVNELDPKIVDMLVEFHKSQGTLETPEAQAEIAQKR
                     EEIEQRRAELEDKKQELLNRLNK"
     gene            complement(8763..9023)
                     /locus_tag="VQ862_001793"
     CDS             complement(8763..9023)
                     /locus_tag="VQ862_001793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001843823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3116095.1"
                     /translation="MTGAGISYMIGRIGALLGGPWGAIIGGAYFGIQAYQSYLDSQSP
                     YPYYITSTYIHVAQRKWKFITEYYRNSNYTGYVKTVTTYVNF"
     gene            complement(9078..9422)
                     /locus_tag="VQ862_001794"
     CDS             complement(9078..9422)
                     /locus_tag="VQ862_001794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000041363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3116096.1"
                     /translation="MSKMFKCMCLLVMSVFCMSSISPSLVVFADDSLSANSKVVSGEA
                     QFENGSSVRFGDTQVNILSDEVLEVVNPDGSVDTIERRADGVYINGAFYMAYQKNEID
                     LNISFRSYDPNV"
     gene            10460..>11418
                     /gene="ltrA"
                     /locus_tag="VQ862_001795"
     CDS             10460..>11418
                     /gene="ltrA"
                     /locus_tag="VQ862_001795"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HET3116097.1"
                     /translation="MSKLLDKILSRENMLEAYNQVKSNKGSAGIDGMTIEEMDNYLRQ
                     NWRLTKELIKQRKYKPQPVLKVEIPKPDGGIRQLGIPTVMDRMIQQAIVQVMSPICEP
                     HFSDTSYGFRPNRSCEKAIMKLLEYLNDGYEWIVDIDLEKFFDTVPQDRLMSLVHNII
                     EDGDTESLIRKYLHSGVIINGQRYKTLVGTPQGGNLSPLLSNIMLNELDKELEKRGLR
                     FVRYADDCVITVGSEAASKRVMYSVSRFIEKRLGLKVNMTKTKITRPRELKYLGFGFW
                     KSSDGWKSRPHQDSVRRFKFKLKKLTQRKWSIDLTRRIEQLNLS"
BASE COUNT         3377 a         2221 c         2603 g         3217 t
ORIGIN      
        1 tatcagataa atggtactat gtcaatggct caggtgccct tgcagtcaac acaactgtag
       61 atggctatgg agtcaatgcc aatggtgaat gggtaaacta aacctaatat aactagttaa
      121 tactgacttc ctgtaagaac tctttaaagt attccctaca aataccatat cctttcagta
      181 gataatatac ccttgtagga agtttagatt aaaaaataac tctgtaatct ctagccggat
      241 ttatagcgct agagactacg gagttttttt gatgaggaaa gaatggcggc attcaagagg
      301 ctctttaaga gagttacggg ttttaaacta ttaagccttc tccaattgca agagggcttc
      361 aatctctgct agggtgctag cttgcgaaat ggctccacgg agtttggcag cgccagatgt
      421 tccacggaga tagtgaggag cgaggccgcg gaattcacga actgcgacgt tttctccttt
      481 gaggttaatc aatcgtttca agtgttcgta ggcgatcttc atcttgtctt caaatgtcaa
      541 atcaggtagg atttctcctg tttcaaagta atggttgatt tggttgaaga ggtaaggatt
      601 tcccatggca gctcggccaa tcatgactgc gtcagcacca acttcttcga tgcgttgctt
      661 ggcttcttgg acagtacgga tatcaccgtt ggcgatgaat ggaatcttgg ttagagcttg
      721 ggcaaccttg taaagggtct caaggtccgc gtggccagta tacatttgtt cacgggtacg
      781 gccatgcatg gcgagggcag aaacacctgc agcctcagca gcgagggcat tttctactgc
      841 aagagatggg tccgcccagc cggtacgcat tttgacagta agtgggatat caaggacaga
      901 ctggaccttg ttgatgatag agtagatctt gtcaggatcc ttgagccaca tagcaccagc
      961 ttcgttcttc acgattttgt tgacagggca gcccatgttg atatcgacga tatcggtctt
     1021 ggtgttttct tggatgaatt ctgctgcgcg tgctaggctg tcttcatcgc taccaaaaag
     1081 ttggatagag acagggtttt cgccctcatc gatatgaagc atgtgcaggg ttttttcgtt
     1141 gttgtattgg attcccttgt cagagaccat ttccattaca acgagtccag ctccgagctc
     1201 ttttgctatg gtacgaaagg ctgagttggt cacgccagcc ataggcgcta aaacggtacg
     1261 attgggaatc tcaatattgc caatcataaa aggtgtatta agatttgtca cgaatgagtt
     1321 cctccaggtc cttttcatca aagttgtaag tagtttggca gaattgacaa gtgatttctg
     1381 caccgtggtc ttcctctttc atttcctgta agtctgagct tggaaggctg gcaagagcgt
     1441 tcataaagcg ttcatggcta cagtcacatt ggaaacggat ttcttcttca gaaagacgct
     1501 tgtaggcttc gtccccgtag atagccttga ggagggcttc gatatggtcg tcgctttcga
     1561 gaagagtaga gatagctggc atttcttgga tgcgtttttc aaagcgagca atctcttctt
     1621 tcttggctcc tggcaagact tgaactagga aaccacctgc aaccttgacc ttgtcttcct
     1681 cgtccaaaag gacattgagg ccgaccgctg aaggcgtttg ttggctttca gtaaggtaaa
     1741 aggcaaggtc ttcaccgatt tctccagaga tgaggggagt tatagagttg taaggatttc
     1801 cagtaccgta gtctgtgata acgaggaatt gaccatttcc aacaaaaggt ccgactagga
     1861 cttcaccagt cgcagtcttt ttgatgtcaa caccaggatt ttgaacatag cctttgacgt
     1921 tccccttggt atcagcgacg gtgataatag cacctagaga gctagatccc aacaccttaa
     1981 ctgtaagttt ggtatttcct ttttcattgg ctgcgagaat ctggctggcg ataagagttc
     2041 gaccaagcgc tacagttgag ctagcttggg tttgatgttt ttcttgagca gtgcggacgg
     2101 tttcagtgct atcaaggaca aaagcacgaa aggctccgct ttctgatata gttttaataa
     2161 ttttatccat agctactatt ttagcataaa aatgcccaaa gggggagccg tgtgtttact
     2221 gattttcagg ataatggacc aggaaatcag catgaaaata aaaagagaaa cagattattt
     2281 tagcatttgt aagatttatg ctatgcttaa ggtagaaaat gaaagggata acaaatgtat
     2341 ttaggagatt tgatggagaa agccgagtgt ggtcaatttt caatcctttc ctttctatta
     2401 caagagtctc agacgaccgt caaggctgta atggaagaaa caggattttc aaaagcaacc
     2461 ctaaccaaat atgtcaccct gctcaatgac aaggctttgg atagtggctt agaactgact
     2521 attcactcag aagatgaaaa tctgcgtctg tctatcggtg cagctaccaa ggggagagat
     2581 attcggagct tgtttttgga gagtgctgtt aaataccaga ttttggttta tcttctctac
     2641 caccaacagt ttttagccca tcagctggct caagaattag tgattagcga ggctacgctt
     2701 ggtcgtcact tggctggttt aaatcagatt ttgtcagaat ttgatttatc catccaaaat
     2761 ggacgttggc gaggtccaga gcatcagatt cgctatttct atttctgtct tttccgaaag
     2821 gtctggtcga gtcaggaatg ggaaggtcac atgcagaaac cagagagaaa acaggagatt
     2881 gccaatttag aggaaatctg cggtgcaagt ttgtctgcgg ggcagaaatt ggacttggtt
     2941 ctctgggctc acatcagtca acaacgtctt cgggtcaatg cttgtcagtt tcaagttata
     3001 gaagagaaaa tgcgagggta ttttgacaat atcttctatc ttcgtttgct gagaaaggtt
     3061 ccgtcctttt ttgctgggca acatattcca ctaggagttg aggatggtga gatgatgata
     3121 ttcttctctt ttctcctatc tcatcgcatt cttcctcttc atactatgga gtatattctt
     3181 ggttttggag ggcagttggc agatttactg acgcaattga ttcaagaaat gaagaaggag
     3241 gaactattgg gggattatac agaggaccat gtcacctatg aactcagtca gctttgtgct
     3301 caagtctatc tctataaggg ctatatttta caggatcgct acaagtacca gttagagaat
     3361 cgtcatccat atttactgat ggaacatgat tttaaagaga cagcagagga gatttttcat
     3421 gctctacctg cttttcaaca ggggacagat ttagataaga agattctctg ggaatggctc
     3481 cagttaatcg aatatatggc tgaaaacggt ggccagcata tgcggattgg tctggatttg
     3541 acatctggtt ttcttgtctt ttcaaggatg gcagccattt tgaaacggta tttggaatac
     3601 aatcgtttta ttaccattga agcttatgac cctagtcggc attatgattt gctggttacc
     3661 aataacccta ttcataagaa ggaacagaca ccagtctatt atttaaaaaa tgacttggat
     3721 atggaagatt tggcagggat tcgtcagtta ttattcactt aaaaggcttg gttaatccag
     3781 gtcttttttg tgaaattcac acaatctcct cacatttttt taaaaattaa aaaaagttga
     3841 taaacaagaa agcgctttat tttgtatact agtaagtgta aagaggaaac acctcaagat
     3901 ctttatcagg aggacagtac atgtcacaag aaaaatacat catggccatt gaccagggaa
     3961 ctacaagttc tcgtgccatc attttcaaca aaaaagggga aaaggttagc tcgagtcaaa
     4021 aagagtttac ccagattttc cctcaagcag gttgggttga gcacaatgcc aatgaaattt
     4081 ggaactctgt tcagtcagtt attgcgggtg ctttcatcga aagtggtgtc aagccaaatc
     4141 aaatcgaggc aatcgggatt accaaccaac gtgaaacaac ggttgtctgg gataagaaaa
     4201 caggacttcc tatctacaat gctatcgttt ggcagtcacg ccagacagca cctttggctg
     4261 agcaactaaa aagccaaggt tatgtggaaa aattccatga aaagactggt ttgattattg
     4321 atgcttactt ctctgctacc aaggttcgtt ggattttgga tcatgtagaa ggtgctcaag
     4381 agcgagcaga aaaaggggaa ttgctctttg gtactatcga tacttggttg gtttggaaat
     4441 tgactgacgg tgcggctcac gtgactgact actcaaatgc agctcgtacc atgctttata
     4501 acattaaaga actcaaatgg gatgatgaga ttttggaaat ccttaacatt ccgaaggcta
     4561 tacttccaga agttcgttct aactccgaaa tctacggcaa gacagctcca ttccatttct
     4621 acggtggaga ggtgccaatc tcaggtatgg ctggggacca acaagcagcc ctctttggac
     4681 agttggcttt tgagccaggt atggttaaga atacttatgg aacaggctct ttcatcatca
     4741 tgaatactgg ggaagagatg cagttgtctg aaaacaacct cttgacaacc attggttacg
     4801 gaatcaacgg taaggtttat tatgccttgg aaggttctat cttcatcgca ggaagtgcta
     4861 ttcagtggct tcgtgacggt cttcgcatgg ttgaaaattc accagaatct gaaaaatacg
     4921 ctcgtgattc tcacaacaac gatgaagttt atgtcgttcc agcctttaca ggtctaggcg
     4981 ctccatactg gaaccaaaat gctcgtggtt ccgtctttgg tttgactcgt ggaacaagca
     5041 aagaagactt tatcaaggcg actttgcaat ctattgctta tcaagtgcgt gacatcatcg
     5101 acaccatgca aatggatact cagaccgcca ttcaagtact gaaggtggat ggtggtgcag
     5161 ccatgaacaa cttcctcatg cagttccagg cggatatttt aggcattgac attgcacgtg
     5221 ctaaaaactt ggaaacaaca gctctaggag cggccttcct agcaggtttg tcagtagggt
     5281 actggaaaga cttggacgag ttgaaactct tgaacgagac aggagaactc tttgagccat
     5341 ctatgaacga atctcgcaag gaacaactct acaagggctg gaagaaggct gtgaaagcaa
     5401 ctcaagtctt tgcggaaatc gatgactaat actcaatgaa aatcaaagag caaactagga
     5461 agctagccgc aagctgtact tgagtacggt aaggcgacgc tgacgtggtt tgaagagatt
     5521 ttcgaagagt ataatactgg cagaataaag cgatttattt agaaagtgtg taaatatgga
     5581 attttcaaag aaaacacgtg aattgtcaat taaaaaaatg caggaacgca ccctggacct
     5641 cttgattatc ggtggaggaa tcacaggagc tggtgtagcc ttgcaggcgg cagctagcgg
     5701 tcttgagact ggtttgattg aaatgcaaga ctttgcagaa ggaacatcta gtcgttcaac
     5761 aaaattggtt cacggaggtc ttcgctacct caaacaattc gacgtagagg tggtctcaga
     5821 tacggtttct gaacgtgcag tggttcaaca aatcgctcca cacattccaa aaccagatcc
     5881 aatgctctta ccagtttacg atgaagatgg agcaaccttt agcctcttcc gtcttaaagt
     5941 agccatggac ttgtacgacc ttttagcagg tgtgagcaac acaccaactg cgaacaaggt
     6001 tttgagcaag gatcaagtct tggaacgcca gccaaacttg aagaaggaag gcttggtagg
     6061 aggtggagtg tatcttgact tccgtaacaa cgatgcgcgt ctcgtgattg aaaacatcaa
     6121 acgtgccaac caagacggtg ccctcattgc caaccacgtg aaggcagaag gcttcctctt
     6181 tgacgaaagt ggcaagatta caggtgttgt agctcgtgat ctcttgacag accaagtatt
     6241 tgaaatcaag gcccgtctgg ttattaatac aacaggtcct tggagtgata aagtacgtaa
     6301 tttgtctaat aagggaacgc aattctcaca aatgcgccca actaagggag ttcacttggt
     6361 agtggattca agcaaaatca aggtttcaca gccagtttac tttgacacag gtttgggtga
     6421 cggtcgtatg gtctttgttc tcccacgtga aaacaagact tactttggta caactgatac
     6481 agactacaca ggtgatttgg agcatccaaa agtaactcaa gaagatgtag attatctact
     6541 tggcattgtc aacaaccgct ttccagaatc caacatcacc attgatgata tcgaaagcag
     6601 ctgggcaggt cttcgtccat tgattgcagg gaacagtgcc tctgactata atggtggaaa
     6661 taacggtacc atcagtgatg aaagctttga caacttgatt gcgactgttg aatcttatct
     6721 ctccaaagaa aaaacacgtg aagatgttga gtctgctgtc agcaagcttg aaagtagcac
     6781 atctgagaaa tatttggatc catctgcagt ttctcgtggg tctagcttgg accgtgatga
     6841 caatggtctc ttgactcttg ctggtggtaa aatcacagac taccgtaaga tggctgaagg
     6901 agctatggag cgcgtggttg acatcctcaa agcagaattt gaccgtagct ttaaattgat
     6961 caattctaaa acttaccctg tttcaggtgg agaattgaac ccagcaaatg tggattcaga
     7021 aatcgaagcc tttgcgcaac ttggagtttc acgtggtttg gatagcaagg aagctcatta
     7081 cctagcaaat ctttacggtt caaatgcacc gaaggtcttt gcacttgctc acagcttgga
     7141 acaagcgcca ggtcttagtt tggcagacac cttgtccctt cactatgcaa tgcgcaatga
     7201 gttgactctt agcccagttg acttccttct tcgtcgtacc aatcacatgc tctttatgcg
     7261 tgatagcttg gatagtatcg ttgagccagt tttggatgaa atgggacgat tctatgactg
     7321 gacagaagaa gaaaaagcaa cttaccgtgc tgatgtcgaa gcagctctcg ctaacaacga
     7381 tttagcagaa ttaaaaaatt aagaaaaaat aaaagaggtg gagggcagca ttccttgtcg
     7441 cccgtccctt ctttttaatg gagacagaaa gatgatgaat gaattatttg gagaatttct
     7501 agggacttta attctgattc ttctaggaaa tggtgttgtt gcaggtgtgg ttcttcctaa
     7561 aaccaagagc aatagctcag gttggattgt gattactatg ggttggggga ttgcagttgc
     7621 ggttgcagtc tttgtatctg gcaagctcag tccagctcat ttaaacccag ctgtgaccat
     7681 cggtgtggcc ttaaaaggtg gtttgccttg ggcttccgtt ttgccttata tcttagccca
     7741 gttcgcaggg gccatgctgg gtcagatttt ggtttggttg caattcaaac ctcactatga
     7801 ggcagaagaa aatgcaggca atatcctggc aaccttcagt actggaccag ccatcaagga
     7861 tactgtatca aacttgatta gcgaaatcct tggaaccttt gttttggtgt tgacaatctt
     7921 tgctttgggt ctttacgatt ttcaggcagg tatcggaacc tttgcagtgg gaactttgat
     7981 tgtcggtatc ggtctatcac taggtgggac aacaggttat gccttgaacc cagctcgtga
     8041 ccttggacct cgtatcatgc acagcatctt gccaattcca aacaagggag acggagactg
     8101 gtcttacgct tggattcctg ttgtaggccc tgttatcgga gcagccttgg cagtgcttgt
     8161 attctcactt ttctagttta tactcttcga aaatcaaatt caaaccacgt cagcgtcgcc
     8221 ttaccgtact caagtacagc ttgcggctag cttcctagtt tgctctttga ttttcattga
     8281 gtattagaaa acaattatgt tgatagagct tgggcaagag cccaatttca gcaaaaaatg
     8341 aagtaaatct tctcataata aaacgcatca tatcaagcac gaaaattcca cgaggtcaac
     8401 tacagtcaga aagctgaaca acaagccaaa acgcccaaaa aaggcggcaa aaagcaagca
     8461 cctgcaagca acgtgccgaa atggtcaaat cctgattatg tcaacgaatt agacccaaaa
     8521 atcgttgata tgctagtaga atttcacaag tcacaaggca ctttggaaac tcccgaggcg
     8581 caagcagaaa tcgcccaaaa acgtgaagaa atcgagcaaa ggagagctga gcttgaggat
     8641 aaaaaacaag agcttttgaa ccgcttgaac aaatagagtt tcgcaagtat tatgcttaca
     8701 aattacttga gcaattaact aaaatataaa ccctgccttt atatctaggc agggtttata
     8761 ttttagaaat tcacgtaggt tgttacggtt tttacatacc cagtatagtt tgagtttcta
     8821 tagtattcag tgataaactt ccattttctt tgagcaacat ggatataagt acttgttatg
     8881 tagtatggat atgggctttg tgaatccaag taagactgat aagcttgtat accaaaatat
     8941 gctccaccaa ttattgcacc ccatggaccc cccaataaag cacctatcct accaatcata
     9001 taactgattc cagcaccagt catgaagtta gcgaatgtgt tagcttgttt attcccatgt
     9061 attgtgttga cgtaatttca aacattagga tcgtatgatc taaaagatat atttaggtcg
     9121 atttcattct tttgataagc catataaaat gccccattga tatagacgcc gtcagcacgt
     9181 cgttcaatag tgtctacact tccatctgga ttgacaacct caagaacttc atcgcttaaa
     9241 atatttactt gcgtatctcc gaaccgcact gatgagccat tctcaaactg agcctcacca
     9301 gatacaactt tagagtttgc cgataagcta tcatcagcaa aaacaacaag cgacggggaa
     9361 atgctagaca tacagaaaac agacataact agcaaacaca tgcatttaaa catcttagac
     9421 ataacggaaa ctcttttgta tttttgattt ttttcaactt ttattataca ataaaaccaa
     9481 ataaaaagaa agcggtaaca atatgcttaa tgcgaaaatt ttttatatat ttttatgttt
     9541 gatcgttatc gaaactacag gcttgttgtt gttgaaaaga ggtctcgaaa tgggttattt
     9601 agacacagaa gctattatcc tcgcagtttt ttcatttgct ttttacaacc tatgttcatt
     9661 cgcttgggtc tgctctacaa taaaaaacaa taaaaaataa atagacgtat tttcaaaaaa
     9721 aaaaaaatgc atatttatct tagcaaaatg acgatttaaa tcgtcgtttt tttgtagtac
     9781 gacgggcatg tcgtatatct gaggtgtaag tcctcggtgg gcacctgcta ccggtgaacc
     9841 caatagcgat tcccaagcct gactatcgtg aggtagcagg gagaggaagg gatagcgaaa
     9901 tcgtggctct acgaacagga acgtgatagt aaggcgtata tagcggataa ggaggcttca
     9961 aactctaaag tccaaaaagg tagtcgtaac ctatatgtgt aaatcacgag agtaattgaa
    10021 ttcggactaa ggtttgtgtg aaaaagataa atctttctag agtctaaaga ctctgcgtca
    10081 gatttcctat tttcactgta accttttaac gtcctcatat cttgtataaa cgaggaaaga
    10141 tgtacgactt atcccgtgag gtttcatgag cgctgaaagc gtagtaacaa cgaatcatga
    10201 gaagtcagcc gagcccatag tagtgaggaa acttctgtag tggaagtgga gcgacggggt
    10261 gaatactcaa acagtctggg gagagactgt ttgaggtctg tcgctagaaa gagaaaacga
    10321 cagatcgaag taatcctact tcacttgtgt ctgtaaaatg agtggtctga tagaactgga
    10381 ctttgacacg taatgactag atgaaggttc accaatataa gatgtccctc aggcaccaaa
    10441 acaagaaagg aataggcaca tgtcaaaact gctagataag atattatcac gcgaaaatat
    10501 gctggaagcc tacaatcaag taaaatccaa taaaggctca gctgggattg atggaatgac
    10561 tatcgaagag atggataatt atctcagaca aaactggcgc ttgactaagg aactgataaa
    10621 acagagaaaa tataagcctc aaccagttct taaagttgag atacctaaac cagacggagg
    10681 catccgtcaa ctaggaattc caacagttat ggatagaatg attcaacagg ccattgtcca
    10741 agtcatgagc cccatttgtg aaccccattt ctcagatacg agttatggtt tcagaccaaa
    10801 taggtcatgt gaaaaagcca tcatgaagct cttagaatac ttaaatgacg gctatgagtg
    10861 gatagtggat atagacctag agaaattttt cgatacagtt cctcaagata gattgatgtc
    10921 cttagtacat aacattatcg aagacggaga tacggaatcc ttgattcgta agtatcttca
    10981 ttcaggtgtt atcattaatg gtcaacgtta taaaacacta gttggtacac cacagggagg
    11041 aaatttatct cctctcttat ccaatatcat gcttaatgaa ttggacaagg aattagaaaa
    11101 gaggggactt cgatttgtgc gctacgcaga tgattgtgtg attacggtcg gaagcgaggc
    11161 agcctctaag cgtgtgatgt attcagtcag tcgttttatt gagaaacggc taggtttgaa
    11221 agtaaacatg accaagacta agattaccag accaagagag ttgaaatatc taggttttgg
    11281 gttctggaaa tcatcagatg gttggaaaag ccgtccacat caagatagtg ttcggagatt
    11341 taagtttaaa ttgaagaaac taacacagag gaaatggagt atagacctaa caagacgtat
    11401 tgagcaactg aatttgtc
//
LOCUS       DAVBOD010000062        11410 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 640-05
            SAMEA1012484-rid20186543.denovo.062, whole genome shotgun sequence.
ACCESSION   DAVBOD010000062 DAVBOD010000000
VERSION     DAVBOD010000062.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012484
            Sequence Read Archive: ERR059358
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11410)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11410)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979948.1
            Genome Coverage       :: 595x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:03:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,266
            CDSs (total)                      :: 2,219
            Genes (coding)                    :: 2,091
            CDSs (with protein)               :: 2,091
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 71 of 128
            Pseudo Genes (incomplete)         :: 50 of 128
            Pseudo Genes (internal stop)      :: 33 of 128
            Pseudo Genes (multiple problems)  :: 22 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11410
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012484-rid20186543.denovo.062"
                     /strain="NIG 640-05"
                     /db_xref="taxon:1313"
     gene            complement(103..2100)
                     /gene="metG"
                     /locus_tag="VQ862_001796"
     CDS             complement(103..2100)
                     /gene="metG"
                     /locus_tag="VQ862_001796"
                     /EC_number="6.1.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine--tRNA ligase"
                     /protein_id="HET3116098.1"
                     /translation="MSEKNFYITTPIYYPSGKLHIGSAYTTIACDVLARYKRLMGYDV
                     FYLTGLDEHGQKIQQKAEEAGITPQAYVDGMAVGVKELWQLLDISYDKFIRTTDDYHE
                     KVVAQVFERLLAQDDIYLGEYSGWYSVSDEEFFTESQLAEVFRDEAGNVTGGIAPSGH
                     EVEWVSEESYFLRLSKYQDRLVEFFKAHPEFITPDGRLNEMLRNFIEPGLEDLAVSRT
                     TFTWGVPVPSNPKHVVYVWIDALLNYATALGYAQDEHGNFDKFWNGTVFHMVGKDILR
                     FHSIYWPILLMMLDVKLPDRLIAHGWFVMKDGKMSKSKGNVVYPEMLVERYGLDPLRY
                     YLMRNLPVGSDGTFTPEDYVGRINYELANDLGNLLNRTVSMINKYFDGQIPAYVEGVT
                     EFDHVLAEVAEQSIADFHTHMEAVDYPRALEAVWTLISRTNKYIDETAPWVLAKDEAL
                     RDQLASVMSHLAASIRVVAHLIEPFMMETSRAVLTQLGLEEVSSLENLSLADFPADVT
                     VVAKGTPIFPRLNMEEEITYIKEQMEGNKPAVEKEWNPDEVELKLNKDEIKFEDFDKV
                     EIRVAEVKEVSKVEGSDKLLQFRLDAGDGEDRQILSGIAKYYPNEQELVGKKVQIVAN
                     LKPRKMMKKYVSQGMILSAEHDGKLTLLTVDPAVPNGSVIG"
     gene            complement(2224..3483)
                     /locus_tag="VQ862_001797"
     CDS             complement(2224..3483)
                     /locus_tag="VQ862_001797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001180420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET3116099.1"
                     /translation="MQNLKFAFSSIMAHKMRSLLTMIGIIIGVSSVVVIMALGDSLSR
                     QVNKDMTKSQKNISVFFSPKKSKDGSFTQKQSAFTVSGKEEEVPVEPPKPQESWVQEA
                     AKLKGVDSYYVTNSTNAILTYQDKKVENANLTGGNRTYMDAVKNEIIAGRSLREQDFK
                     EFASVILLDEELSISLFESPQEAINKVVEVNGFSYRVIGVYTSPEAKRSKIYGFGGLP
                     ITTNISLAANFNIDEIASIVFRVNDTSLTPTLGPELARKMTELAGLQQGEYQVADESV
                     VFAEIQQSFSFMTTIISSIAGISLFVGGTGVMNIMLVSVTERTREIGLRKALGATRAN
                     ILIQFLIESMILTLLGGLIGLTIASGLTALAGLLLQGLIEGIEVGVSIPVALFSLAVS
                     ASVGMIFGVLPANKASKLDPIEALRYE"
     gene            complement(3485..4186)
                     /locus_tag="VQ862_001798"
     CDS             complement(3485..4186)
                     /locus_tag="VQ862_001798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3116100.1"
                     /translation="MKQLISLKNIFRSYRNGDQELQVLKNINLEVNEGEFVAIMGPSG
                     SGKSTLMNTIGMLDTPTSGEYYLEGQEVAGLGEKQLAKVRNQQIGFVFQQFFLLSKLN
                     ALQNVELPLIYAGVSSSKRRKLAEEYLDKVELTERSHHLPSELSGGQKQRVAIARALV
                     NNPSIILADEPTGALDTKTGNQIMQLLVDLNKEGKTIIMVTHEPEIAAYAKRQIVIRD
                     GVISSDSAQLGKEEN"
     gene            complement(4170..5369)
                     /locus_tag="VQ862_001799"
     CDS             complement(4170..5369)
                     /locus_tag="VQ862_001799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000728654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter periplasmic adaptor
                     subunit"
                     /protein_id="HET3116101.1"
                     /translation="MKKKNGKAKKWQLYAAIGAASVVVLGAGGILLFRQPSQTAVKDE
                     PTHLVVAKEGSVASSVLLSGTVTAKNEQYVYFDASKGDLDEILVSVGDKVSEGQALVK
                     YSSSEAQAAYDSASRAVAKADRHINELNQARNEAASAQAPQLPAPVGGEDATVQSPTP
                     VAGNSVASIDAQLGDARDARADAAAQLSKAQSQLDATTVLSTLEGTVVEVNSNVSKSP
                     TGASQVMVHIVSNENLQVKGELSEYNLANLSVGQEVSFTSKVYPDKKWTGKLSYISDY
                     PKNNGEAASPAAGNNTGSKYPYTIDVTGEVGDLKQGFSVNIEVKSKTKAILVPVSSLV
                     MDDSKNYVWIVDEQQKAKKVEVSLGNADAENQEITSGLTNGAKVISNPTSSLEEGKEV
                     KADEATN"
     gene            5634..6980
                     /gene="gor"
                     /locus_tag="VQ862_001800"
     CDS             5634..6980
                     /gene="gor"
                     /locus_tag="VQ862_001800"
                     /EC_number="1.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-disulfide reductase"
                     /protein_id="HET3116102.1"
                     /translation="MREYDIIAIGGGSGGIATMNRAGEHGAKAAVIEEKKLGGTCVNV
                     GCVPKKIMWYGAQIAETFHQFGEDYGFKTTDLNFDFATLRRNREAYIDRARSSYDSSF
                     KRNGVDLIEGHAEFVDSHTVSVNGELIRAKHIVIATGAHPSIPNIPGAELGGSSDDVF
                     AWEELPESVAILGAGYIAVELAGVLHTFGVKTDLFVRRDRPLRGFDSYIVEGLVKEME
                     RINLPLHTHKVPAKLEKTAKGITIHFEDGTSHTASQVIWATGRRPNVKSLQLEKAGVT
                     LNERGFIQVDEYQNTVVEGIYALGDVTGEKELTPVAIKAGRTLSERLFNGKTTAKMDY
                     STIPTVVFSHPAIGTVGLTEEQAIKEYGQDQIKVYKSSFTSMYSACTCNRQETRFKLI
                     TAGSEEKVVGLHGIGYGVDEMIQGFAVAIKMRATKADFDATVAIHPTSSEEFVTMR"
     gene            7176..7712
                     /locus_tag="VQ862_001801"
     CDS             7176..7712
                     /locus_tag="VQ862_001801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000709035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin transporter BioY"
                     /protein_id="HET3116103.1"
                     /translation="MKKAHVYAIPAIGAALIAVLAQISLPIGPVPFTLQNFAIGLIAT
                     VFRPREAVLSAGLYLLLGAIGLPVFAGGGAGFQALVGPTAGYLWFYLVYSGLTSSLTN
                     SKSGVVKIFLANLLGDALVFVGGILSLHFLAGMAFEKALAVGVLPFIIPDLGKLLAIS
                     FISRPLLQRLKNQAYFTN"
     gene            7763..7849
                     /locus_tag="VQ862_001802"
                     /pseudo
     CDS             7763..7849
                     /locus_tag="VQ862_001802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(7918..8133)
                     /locus_tag="VQ862_001803"
     CDS             complement(7918..8133)
                     /locus_tag="VQ862_001803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000807422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdbC family protein"
                     /protein_id="HET3116104.1"
                     /translation="MAEFTFEIEEHLLTLSENEKGWTKEINRVSFNGAPAKFDIRAWS
                     PDHTKMGKGITLSNEEFQTMVDAFKGN"
     gene            8231..8551
                     /locus_tag="VQ862_001804"
     CDS             8231..8551
                     /locus_tag="VQ862_001804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001216095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3116105.1"
                     /translation="MRHKFQQVLNKIHDFLNGYDQPDQTETNSLTATIEEAIQKQTAV
                     HLILSETSFTGDIIKYDQQGQQIIVKNFAKNVSRIIRISDIQRLRFVPSTVQTAQKNR
                     FKKE"
     gene            complement(8582..8920)
                     /locus_tag="VQ862_001805"
     CDS             complement(8582..8920)
                     /locus_tag="VQ862_001805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001196050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3116106.1"
                     /translation="MQVIKRNGEIAEFNPDKIYQAILKAAQTVYVLTDDLRQNLAQVT
                     KKVVLDLQEAKVERATISMIQSMVEHRLLGAGYITIAEHYISYRLQRDLERSGYGDHI
                     AVHLHFEQIR"
     gene            complement(8932..9651)
                     /gene="trmD"
                     /locus_tag="VQ862_001806"
     CDS             complement(8932..9651)
                     /gene="trmD"
                     /locus_tag="VQ862_001806"
                     /EC_number="2.1.1.228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(37)-N1)-methyltransferase TrmD"
                     /protein_id="HET3116107.1"
                     /translation="MKIDILTLFPEMFSPLEHSIVGKAREKGLLDIQYHNFRENAEKA
                     RHVDDEPYGGGQGMLLRAQPIFDSFDAIEKKNPRVILLDPAGKQFDQVYAEDLAQEEE
                     LIFICGHYEGYDERIKTLVTDEISLGDYVLTGGELAAMTMIDATVRLIPEVIGKESSH
                     QDDSFSSGLLEYPQYTRPYDYRGMVVPDVLMSGHHEKIRQWRLYESLKKTYERRPDLL
                     EHYQLTVEEEKMLAEIKENKE"
     gene            complement(9641..10159)
                     /gene="rimM"
                     /locus_tag="VQ862_001807"
     CDS             complement(9641..10159)
                     /gene="rimM"
                     /locus_tag="VQ862_001807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimM"
                     /protein_id="HET3116108.1"
                     /translation="MNYFNVGKIVNTQGLQGEMRVLSVTDFAEERFKKGAELALFDEK
                     DQFVQTVTIASHRKQKNFDIIKFKDMYHINTIEKYKGYSLKVAEEDLNDLDDGEFYYH
                     EIIGLEVYEGDSLVGTIKEILQPGANDVWVVKRKGKRDLLLPYIPPVVLNVDIPNKRV
                     DVEILEGLDDED"
     gene            complement(10190..10978)
                     /locus_tag="VQ862_001808"
     CDS             complement(10190..10978)
                     /locus_tag="VQ862_001808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000819180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HET3116109.1"
                     /translation="MKRFEVSTEIGSLSVTYQKQKKVLVCLNGAGLLPSYENFSLILE
                     KPPPTIGYLTIDFPNTGRSPIHDQAGKNLDNLADAVYEVLEELGISEYILCAHSWSGI
                     LACKLLEKPIKRQTLVAIEPTTKKVMFADFSENPYPEMEEQMRLIDECGPELYFKNLT
                     QATFSPETNKKIWELMQEKGLELENQDPEFQISGEITEEDFENLSIESHVPVFIFCQT
                     YREKEYRESEYWTSNTKLILGRNHHYLQWSESEKIAAIIRELSE"
     gene            complement(11082..11325)
                     /locus_tag="VQ862_001809"
                     /pseudo
     CDS             complement(11082..11325)
                     /locus_tag="VQ862_001809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000779614.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide pyrophosphohydrolase"
BASE COUNT         3274 a         2508 c         2077 g         3551 t
ORIGIN      
        1 cagtgctttg atcaacccgc ggctagcttc ctagtttgct ctttgatttt cattgagtat
       61 aaataaaaaa acagaactag tctgaactag tcctgtctac ttttacccaa tcacacttcc
      121 atttggtaca gctggatcaa ctgtgagaag ggttaatttg ccatcatgtt cagctgatag
      181 aatcataccc tggctgacat attttttcat cattttacgt ggtttgaggt tagcaacgat
      241 ttgaactttc ttgccgacca attcttgttc atttggatag tattttgcaa ttcctgaaag
      301 aatctgacga tcttctccat caccagcatc caagcggaat tgaagcaact tatctgaacc
      361 ttctacttta gacacttctt tgacttctgc gacacggatt tcaaccttgt caaagtcttc
      421 aaacttgatt tcatccttgt ttagtttgag ctcaacttcg tccggattcc attctttttc
      481 gactgctggt ttattgcctt ccatttgttc cttgatatag gtgatttctt cttccatatt
      541 tagacgtgga aagataggtg ttcctttggc aactacagtc acatctgctg ggaagtcagc
      601 caaactcaag ttttcaagac tagaaacttc ttccaaacca agttgagtca aaactgcacg
      661 actagtttcc atcataaatg gttcaatcaa gtgagcaact acacgaatgc tggctgccaa
      721 gtggctcatg acacttgcca attggtcacg aagagcttca tccttggcca agacccatgg
      781 tgcggtctca tcgatgtatt tattggtacg agagatcaga gtccagactg cttcaagcgc
      841 acgtggatag tcaactgctt ccatgtgtgt atggaagtct gcgattgatt gttctgcaac
      901 ctcagcaaga acatgatcaa attcagtcac accttctaca taggcaggga tttgtccatc
      961 aaagtactta ttaatcatgg aaaccgtacg gttaaggagg ttcccaaggt cattagccaa
     1021 ttcatagttg atacggccga catagtcttc aggagtaaag gttccgtctg aaccaactgg
     1081 aaggttacgc atgaggtagt aacgaagtgg atctagtcca taacgctcta ccaacatttc
     1141 agggtaaacg acattccctt ttgacttaga catttttccg tctttcatga caaaccaacc
     1201 atgggcaatc aaacgatcag gtaatttaac atccaacatc ataagaagga ttggccagta
     1261 gatagagtgg aagcgaagga tatcttttcc taccatatgg aagactgttc cattccagaa
     1321 cttgtcaaag ttaccatgtt cgtcttgagc gtagccaaga gctgtcgcat agttaagaag
     1381 ggcatcaatc caaacgtaga caacgtgttt tggatttgat gggacaggca ctccccatgt
     1441 aaaggttgta cgagataccg ccaaatcttc caaacctggc tcgatgaagt tgcgtagcat
     1501 ttcattaagg cgaccatctg gcgtgataaa ttcaggatga gctttgaaaa attcgaccaa
     1561 acggtcttgg tatttgctaa ggcgaagaaa gtatgattct tcagaaaccc attcaacctc
     1621 atggcctgat ggagcaatac caccagtcac atttccagct tcatcacgga aaacttctgc
     1681 cagctggctt tctgtaaaga attcttcgtc tgatactgaa taccaaccag agtattcacc
     1741 caagtagata tcatcttgag caagtaagcg ttcaaagact tgtgcgacaa ctttttcatg
     1801 gtagtcatca gttgtacgga taaatttatc gtatgagata tctagtaatt gccagagttc
     1861 tttaactcca accgccattc catcaacata ggcttgaggt gtaataccag cttcttccgc
     1921 tttctgctgg attttctgac catgttcatc aagacctgtc agataaaata catcgtagcc
     1981 catcaggcgt ttgtaacgtg ctaggacatc acatgcgata gttgtgtagg cagaaccgat
     2041 atgaagtttc ccagatggat agtaaatcgg cgttgtaata taaaaatttt tttcagacat
     2101 aatttttcct ttccaggcaa atgaaacctg tttttctaac acttcattat atcacatttt
     2161 taatgaattt cgatagggaa atccatacaa aaacaagata gacgagtgtc catcttgttg
     2221 atctcattca taacgaaggg cttcaattgg atcaagtttc gatgccttgt tggctggcaa
     2281 gactccaaaa atcataccaa cactagccga aactgcaaga ctaaataggg caactgggat
     2341 tgatactcca acttctatac cttctattaa accttgcagt aacaaacctg ctaaggcagt
     2401 taaaccactt gcaattgtca agccaattaa gccacctaac aaggtcaaaa tcatggattc
     2461 aatcaaaaac tgaattaaaa tattggcacg tgttgcgccc aaagccttac gaagaccaat
     2521 ctcacgagtg cgctctgtca ccgaaaccag catgatgttc atgacaccag ttcctccaac
     2581 aaagagagaa atccctgcga tggaactaat aatcgtcgtc ataaaactaa acgattgttg
     2641 aatttctgca aatacaacgg actcatctgc cacctggtat tctccctgtt gtaagcctgc
     2701 aagctctgtc atttttcgtg ccagttctgg acccagagtt ggggttaaac tggtatcatt
     2761 cactcgaaag acaatactag ctatttcatc tatattaaaa ttcgcagcaa gggagatatt
     2821 ggtagtaata ggcaagccac caaacccata tatttttgac cttttagcct ccggactagt
     2881 ataaacccca atgacccggt aactaaatcc attgacttct acaaccttgt taatagcctc
     2941 ttgaggagat tcaaataaac taatggacaa ttcctcatct agcaaaataa cacttgcaaa
     3001 ctctttgaaa tcttgctctc tcagactacg acctgcaata atttcattct taacagcgtc
     3061 catgtaagtt ctgtttccac ctgtcaaatt agcattctca acctttttat cttgataggt
     3121 caagatggca ttcgttgaat tggttacata gtaactatcc actcccttca gtttagctgc
     3181 ctcttgaacc caggattctt gcggttttgg cggttcaaca ggaacttcct cttcctttcc
     3241 agaaaccgta aaagctgatt gtttctgagt aaaagaccca tctttacttt ttttaggaga
     3301 gaaaaagacg ctaatatttt tctgagattt agtcatatct ttattgactt gacgagatag
     3361 ggaatcaccc aaagccataa tcacaacaac tgatgaaaca ccgataataa tcccaatcat
     3421 agtaagcaaa gaacgcatct tgtgagccat gatagatgaa aaggcaaatt tcagattctg
     3481 catcttagtt ttcctccttt cctaactgag cactgtcaga cgaaatgacc ccatcccgaa
     3541 tgacaatctg acgtttggca taggcagcaa tctcaggctc atgcgttacc atgataatgg
     3601 tttttccttc tttattcaaa tcaaccaata attgcataat ttggttacct gttttggtat
     3661 ccaaggctcc tgtcggttca tccgctagga taatagaagg attgtttacc aaggcacgcg
     3721 caatggctac acgttgcttt tgaccaccag ataattctga aggtaaatgg tgactacgtt
     3781 ctgtcaattc aaccttgtct aaatattcct cagccaactt gcgacgtttt gaagacgaaa
     3841 ctcctgcgta aatcaagggc aattctacat tttgcagagc attgagcttc gatagaagaa
     3901 agaactgctg aaagacaaaa ccgatttgtt ggttacgaac cttagctagt tgtttttcac
     3961 caagcccagc cacttcttga ccttcaagat aatattctcc actggttggt gtatccaaca
     4021 tgccaatcgt attcatcaga gtggacttac cagaaccaga tggccccatg atggctacaa
     4081 attcaccctc attcacttct agattgatat ttttgagaac ctgcagttct tggtcaccat
     4141 tacggtagct tctgaagata ttttttagac taattagttg cttcatcagc cttcacctct
     4201 tttccttctt ccaaggaaga tgttggatta ctgatgacct tagcaccatt tgtcaaacca
     4261 gaagtgattt cttgattttc tgcgtcagca tttcccaatg aaacctcaac ttttttagcc
     4321 ttttgttgtt catccacaat ccagacataa tttttactat catccattac tagactgcta
     4381 acaggaacaa gaatagcctt agttttgctt ttaacctcaa tgttgacaga aaaaccttgt
     4441 ttcaaatcac caacctcgcc tgtcacatca atagtataag ggtatttaga acctgtatta
     4501 ttcccggctg ctggactagc tgcttcacca ttgtttttag gatagtcaga aatatagctt
     4561 aatttcccag tccatttttt atcaggatac actttagaag taaagcttac ttcttgacct
     4621 acagaaaggt tggctagatt gtactcagac aattctccct tgacttgtaa attttcattg
     4681 ctgacaatat gaaccataac ttgactcgcc cctgttggag atttagaaac attgctattg
     4741 acttcgacta cagttccctc tagggtactg agaacagttg ttgcatccaa ttgactttga
     4801 gccttgctta attgcgctgc agcatctgca cgcgcatcac gggcatcacc caattgagca
     4861 tcaatagaag caacagaatt tccagccact ggagttgggc tttgcaccgt tgcatcttct
     4921 cctcctactg gcgctggtaa ctgtggagcc tgagctgaag cggcttcatt tcgtgcttga
     4981 ttgagttcat tgatatgacg atctgcctta gctactgctc gactagctga atcataggcc
     5041 gcctgcgctt ctgaactact gtacttgact aaagcctgcc cttcgctgac cttatcgccc
     5101 acagaaacaa ggatttcatc taaatcaccc ttactagcat caaaataaac atattgttca
     5161 ttttttgctg ttactgtccc tgacaataaa acagaggatg ccacgcttcc ttccttggca
     5221 acaacaagat gagtaggctc atcttttaca gcagtctgag aaggttgtct aaaaagtaaa
     5281 atccccccgg cacccaatac aactacactc gcagcaccga ttgctgcata cagttgccac
     5341 tttttagctt taccattctt tttcttcata atgaaactcc ttttcttttt tacaatactt
     5401 tgctattata ccaaatttcc ctccagcaaa caatacagtt caggattaag caatcgttcg
     5461 gaatttttct tttctattgt actagatata taatacacta tcttgactta tttggcaagc
     5521 ttttttgcaa ttttttgtgc gtagcagatt tttgcaatca aatcaaaaaa agaataaaat
     5581 ataactatca aaaaagacgc tctactattt aaaagattac aaaggagttt tcaatgagag
     5641 aatatgatat cattgctatc ggtggaggta gcggaggaat cgctaccatg aaccgtgctg
     5701 gtgaacatgg agccaaagca gccgttattg aggaaaagaa attaggtgga acctgtgtca
     5761 acgtcggttg tgttcctaaa aaaatcatgt ggtacggggc gcaaatcgct gagactttcc
     5821 atcaatttgg agaagactac ggctttaaga ctactgatct taactttgac tttgcaaccc
     5881 tacgtcgcaa tcgtgaagcc tacattgatc gcgctcgttc ttcttatgat agtagtttta
     5941 aacgcaacgg tgtagacttg attgaaggtc atgctgaatt tgtagattct catactgtaa
     6001 gcgtaaatgg tgaactgatt cgtgctaaac atatcgtgat tgctacaggt gcccatccaa
     6061 gtattcctaa tattcctggt gctgagctag gtggctcttc tgatgatgta tttgcctggg
     6121 aagaacttcc agagtcagtt gccattctag gcgctggtta tatcgccgtt gaattagctg
     6181 gcgtactcca cacttttggt gtcaagacag atctctttgt tcgccgcgat cgtcctttac
     6241 gtggttttga ttcctacatc gttgaaggtt tggtcaagga aatggaaaga ataaacttgc
     6301 cacttcatac tcacaaagtc cctgccaagt tagaaaaaac tgctaaaggc attaccattc
     6361 atttcgagga tggtaccagt cacacagcta gccaagttat ctgggctaca ggtcgccgtc
     6421 caaacgttaa gagcttgcaa cttgaaaaag ctggagtgac tctgaatgaa cgtggcttta
     6481 tccaagtaga tgaataccaa aatactgttg ttgagggaat ctatgctcta ggtgatgtaa
     6541 caggtgaaaa agaactgact ccagttgcaa tcaaggctgg gcgtacccta tcagaacgtc
     6601 tctttaacgg aaaaacaact gcaaaaatgg attactcaac tattccaact gttgtctttt
     6661 cacaccctgc tatcggaact gttggtttga cagaagaaca agctattaaa gaatacggtc
     6721 aagaccaaat caaggtttac aaatcaagct ttacttctat gtactctgct tgcacttgca
     6781 accgtcaaga aactcgtttc aaattgatca cagctggttc agaagaaaaa gttgtcggac
     6841 ttcacggaat tggctacggc gttgatgaaa tgattcaagg atttgctgtt gctatcaaaa
     6901 tgagagcaac caaggctgac tttgacgcaa ctgtagcgat tcacccaact tcatctgaag
     6961 aatttgtaac catgcgttaa tcgaaacaaa agaagctgat ataaatatgt ctgcttcttt
     7021 tttaatgatt ttcgaatcaa caaaaaatta tccaacttga ctagtcacga aaatcggctg
     7081 ttacagtttt tgttaccttg tttttaaaaa atggttgaca tcgactccta tatgagtata
     7141 atagttacta tacattagaa aagaggttaa ctattttgaa aaaagctcac gtttatgcta
     7201 tccctgctat tggggctgct ctcattgctg ttttggcaca aatcagtctt ccaattggac
     7261 ctgttccctt cactctgcaa aactttgcaa tcggcttgat tgctactgtc tttagaccga
     7321 gagaggctgt actttctgct ggactctatc ttcttctagg tgctatcggt cttcctgtct
     7381 ttgcaggagg tggagctggt tttcaggctt tagttggccc tactgcaggc tatctttggt
     7441 tttatctcgt ttactctgga cttacttcct ctctaaccaa cagcaagagt ggtgttgtta
     7501 agatttttct tgcaaacctc ttgggtgatg cccttgtctt tgtcggcggg attctcagct
     7561 tgcatttcct agctggaatg gcatttgaaa aagctcttgc tgtgggggtt cttcccttta
     7621 tcattccaga ccttggcaaa cttctggcta ttagttttat tagccgtccc ctacttcaac
     7681 gccttaaaaa tcaggcttac tttactaact aaaaaaggat atcgagttat catgactcaa
     7741 tatccttttc ttttattttg aaaacttata ctcaatgaaa atcaaagagc aaactagaaa
     7801 gctagccgca ggctgctcaa aacactgttt tgaggttgtg gatgaaactg acgaagtcag
     7861 taaccataca tacggcaagg caaagctgac gcggtttgaa gagattttcg aagagtatta
     7921 gttgccttta aaggcatcca ccatcgtttg aaattcttca tttgagagag taatcccttt
     7981 gcccatttta gtatggtctg gactccaagc acgaatatca aactttgcag gggcaccatt
     8041 aaagctcaca cggttaattt ccttggtcca acctttttcg ttttcagaaa gagtcaacaa
     8101 gtgctcttcg atttcaaatg taaattctgc cattttcttc tcctttttta gtttcattag
     8161 tttattcgta aaatcttgta gattttagga aaattttata taatattgat ataaaagaag
     8221 ggaggccaat atgagacata aattccagca agttctaaat aaaatacatg attttttaaa
     8281 tggatatgac caacctgacc agactgaaac caactccctt acagccacta ttgaagaggc
     8341 tatccagaaa caaaccgctg ttcaccttat cttgtctgag acaagtttta caggtgatat
     8401 catcaaatat gatcagcaag gccagcaaat tatcgtgaaa aattttgcca aaaatgtgag
     8461 ccggattatc cgtataagcg atattcaacg cctgcgattt gtcccctcaa ctgtccaaac
     8521 agcccaaaaa aatagattta agaaagagtg agatgtagtt gcttcatccc actctttttt
     8581 cttagcgaat ttgttcaaaa tgtaaatgaa ctgcaatatg atctccataa ccacttcttt
     8641 ccaagtcacg ttgtaaacga taggaaatgt agtgttctgc aatggtaatg taacctgcgc
     8701 ccaataaacg atgttcaacc atagattgaa tcatactgat agtcgcacgt tccaccttgg
     8761 cttcttgtaa atccaaaact accttcttag tgacttgagc aagattttga cgcaaatcat
     8821 ctgtcaaaac ataaacagtt tgggctgcct tcaagatggc ttggtaaatc ttatctggat
     8881 taaattcagc aatttcgcca ttacgtttga ttacttgcat aggtttctcc tttattcttt
     8941 gttttctttg atttctgcca gcattttttc ttcttctact gtcagttgat aatgttcaag
     9001 taaatccggt ctgcgctcgt aggttttctt taaactctcg tacaatcgcc actgacgaat
     9061 cttttcatgg tggccactca tcaatacatc tggcacgacc atgcctcgat aatcataggg
     9121 acgtgtgtac tgaggatatt ctaaaagacc tgaagaaaaa ctatcatctt ggtggctaga
     9181 ctccttgcca atcacttctg gaatcaggcg aactgtagca tcaatcatgg tcatagctgc
     9241 caattctcca ccagtgagga catagtcgcc tagggaaatc tcatctgtta ccaaggtctt
     9301 aatgcgctca tcataaccct catagtgccc acagataaag attagctctt cctcttgagc
     9361 caaatcttca gcataaacct gatcaaactg ctttccagca ggatcgagga gaataacgcg
     9421 cggatttttc ttttcaatag catcaaagga atcgaaaata ggttgtgctc tgagcaacat
     9481 gccctgaccg cctccgtagg gctcatcatc tacatgacgg gccttttcag cattttctcg
     9541 aaaattatga tactggatat ccaagagccc tttttctcga gcctttccaa cgattgagtg
     9601 ctccagtgga gaaaacatct ctggaaagag ggttaaaata tcaatcttca tcgtctaacc
     9661 cttctaagat ttccacatcg acccgtttat ttggaatatc aacattgaga accactggtg
     9721 ggatataagg taaaagcaaa tcacgtttgc cttttcgttt gaccacccag acatcattag
     9781 cacctggttg caggatttcc ttgatggttc caaccaagct atcaccctca tagacttcca
     9841 aaccgataat ctcgtgatag taaaattcac catcgtctag gtcattcaaa tcttcctcag
     9901 cgaccttgag actgtatccc ttgtactttt cgatagtatt gatatggtac atatctttga
     9961 atttaataat gtcaaagttc ttctgtttac ggtggctagc gatggtcact gtttggacaa
    10021 actgatcttt ttcatcaaac aaagccagct cagctccttt tttaaaccgt tcttctgcaa
    10081 aatccgtcac agacaagact cgcatctcac cctgtaatcc ctgcgtatta acgattttcc
    10141 caacattaaa gtagttcatc ttgtctcctg taatctcctt ttttccatct tattctgaca
    10201 attctcgaat aatagccgca attttttccg attctgacca ttgtaaataa tggtgattcc
    10261 ttcctaaaat gagtttagta ttggaagtcc aatattctga ttctctgtac tctttttctc
    10321 tataagtctg acaaaaaata aatacaggga catgagattc tatcgacaaa ttctcaaaat
    10381 cttcctcagt aatctctcca gatatctgaa attctggatc ttgattttcc aactctaagc
    10441 ctttttcttg cattaattcc cagatttttt tattcgtttc aggactaaat gttgcttgag
    10501 ttaagttctt aaaataaagt tcaggaccac actcgtcaat cagcctcatc tgctcttcca
    10561 tttctggata aggattttct gaaaaatcag caaacatgac ttttttagtt gtcggttcaa
    10621 ttgctactaa agtctgacgc ttaattggtt tctcgagtaa tttgcaagct aaaattccac
    10681 tccaactatg tgcacaaagt atatattcag aaattcctaa ttcttcaagt acttcataaa
    10741 ccgcatctgc aagattatct agattttttc cagcttggtc atgaatcgga ctcctacctg
    10801 tgttcggaaa atcaattgtc aaataaccaa ttgtaggagg aggtttttca agtataagtg
    10861 aaaaattttc ataacttggt agcaaacctg ctccgtttag acaaactagc actttctttt
    10921 gcttttgata agtaacagag aggctaccaa tttctgtaga tacttcaaac ctcttcataa
    10981 agaaatccac tcattctata taatgaatta ttaaaaatcc ttatccttta ttttatcacg
    11041 ttccaaagat tttctcaagt tggaggaagg ggacaacatc tctactttcc cttcaagaat
    11101 ccttccaaat catgtttatg ttggtaatta acggctgcgg ttttgtcttt ctcaaagatg
    11161 gttctagtta ggtcaatatg cttgatagca gcaatagcga cggtgtagtg aatgatatca
    11221 gccagttcta tggcaggttc ctcgttcgaa tcctatccct tcttttcgac cagagcgcct
    11281 attcaaaacc tcggctactt ctccgacttc ctccactaac ttcataaaga gaccttcatc
    11341 agtccgagac tgctgttaat gttcgagtaa gtagtcttgg aattgcctaa acgttcaatc
    11401 ttttatagta
//
LOCUS       DAVBOD010000063        11265 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 640-05
            SAMEA1012484-rid20186543.denovo.063, whole genome shotgun sequence.
ACCESSION   DAVBOD010000063 DAVBOD010000000
VERSION     DAVBOD010000063.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012484
            Sequence Read Archive: ERR059358
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11265)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11265)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979948.1
            Genome Coverage       :: 595x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:03:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,266
            CDSs (total)                      :: 2,219
            Genes (coding)                    :: 2,091
            CDSs (with protein)               :: 2,091
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 71 of 128
            Pseudo Genes (incomplete)         :: 50 of 128
            Pseudo Genes (internal stop)      :: 33 of 128
            Pseudo Genes (multiple problems)  :: 22 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11265
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012484-rid20186543.denovo.063"
                     /strain="NIG 640-05"
                     /db_xref="taxon:1313"
     gene            complement(391..1527)
                     /gene="dnaJ"
                     /locus_tag="VQ862_001810"
     CDS             complement(391..1527)
                     /gene="dnaJ"
                     /locus_tag="VQ862_001810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001066288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaJ"
                     /protein_id="HET3116110.1"
                     /translation="MNNTEFYDRLGVSKNASADEIKKAYRKLSKKYHPDINKEPGAED
                     KYKEVQEAYETLSDDQKRAAYDQYGAAGANGGFGGAGGFGGFNGAGGFGGFEDIFSSF
                     FGGGGSSRNPNAPRQGDDLQYRVNLTFEEAIFGTEKEVKYHREAGCRTCNGSGAKPGT
                     SPVTCGRCHGAGVINVDTQTPLGMMRRQVTCDVCHGRGKEIKYPCTTCHGTGHEKQAH
                     SVHVKIPAGVETGQQIRLAGQGEAGFNGGPYGDLYVVVSVEASDKFEREGTTIFYNLN
                     LNFVQAALGDTVDIPTVHGDVELVIPEGTQTGKKFRLRSKGAPSLRGGAVGDQYVTVN
                     VVTPTGLNDRQKVALKEFATAGDLKVNPKKKGFFDHIKDAFDGE"
     gene            complement(1732..2085)
                     /locus_tag="VQ862_001811"
     CDS             complement(1732..2085)
                     /locus_tag="VQ862_001811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000115730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3116111.1"
                     /translation="MSVNKNNLSDIADYHEKIKFFEELFNLDYNPTEMLVTVERNGNV
                     IYKEFTEVAVGKSKYDYTSVFKDVMIYFSDHICQELHLYKTQDPHYNKFEFDLAKRSL
                     KITTRDNTTIFISNE"
     gene            complement(2098..3921)
                     /gene="dnaK"
                     /locus_tag="VQ862_001812"
     CDS             complement(2098..3921)
                     /gene="dnaK"
                     /locus_tag="VQ862_001812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002946936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaK"
                     /protein_id="HET3116112.1"
                     /translation="MSKIIGIDLGTTNSAVAVLEGTESKIIANPEGNRTTPSVVSFKN
                     GEIIVGDAAKRQAVTNPDTVISIKSKMGTSEKVSANGKEYTPQEISAMILQYLKGYAE
                     DYLGEKVTKAVITVPAYFNDAQRQATKDAGKIAGLEVERIVNEPTAAALAYGLDKTDK
                     EEKILVFDLGGGTFDVSILELGDGVFDVLSTAGDNKLGGDDFDQKIIDHLVAEFKKEN
                     GIDLSTDKMAMQRLKDAAEKAKKDLSGVTSTQISLPFITAGEAGPLHLEMTLTRAKFD
                     DLTRDLVERTKVPVRQALSDAGLSLSEIDEVILVGGSTRIPAVVEAVKAETGKEPNKS
                     VNPDEVVAMGAAIQGGVITGDVKDVVLLDVTPLSLGIETMGGVFTKLIDRNTTIPTSK
                     SQVFSTAADNQPAVDIHVLQGERPMAADNKTLGRFQLTDIPAAPRGIPQIEVTFDIDK
                     NGIVSVKAKDLGTQKEQTIVIQSNSGLTDEEIDRMMKDAEANAEADKKRKEEVDLRNE
                     VDQAIFATEKTIKETEGKGFDAERDAAQAALDDLKKAQEDNNLDDMKAKLEALNEKAQ
                     GLAVKLYEQAAAAQQAQEGAEGAQATGNAGDDVVDGEFTEK"
     gene            complement(4401..4925)
                     /gene="grpE"
                     /locus_tag="VQ862_001813"
     CDS             complement(4401..4925)
                     /gene="grpE"
                     /locus_tag="VQ862_001813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000046028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide exchange factor GrpE"
                     /protein_id="HET3116113.1"
                     /translation="MAQDIKNEEVEEVQEEEVVETAEETTPEKSELDLANERADEFEN
                     KYLRAHAEMQNIQRRANEERQNLQRYRSQDLAKAILPSLDNLERALAVEGLTDDVKKG
                     LGMVQESLIHALKEEGIEEIAADGEFDHNYHMAIQTLPADDEHPVDTIAQVFQKGYKL
                     HDRILRPAMVVVYN"
     gene            complement(4952..5986)
                     /gene="hrcA"
                     /locus_tag="VQ862_001814"
     CDS             complement(4952..5986)
                     /gene="hrcA"
                     /locus_tag="VQ862_001814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heat-inducible transcriptional repressor HrcA"
                     /protein_id="HET3116114.1"
                     /translation="MVTERQQDILNLIIDIFTKTHEPVGSKALQESINSSSATIRNDM
                     AELEKQGLLEKAHTSSGRMPSVAGFQYYVKHSLDFHRLAENEVYEIVKAFDQEFFKLE
                     DILQEAANLLTDLSGCTVVALDVEPSRQRLTAFDIVVLGQHTALAVFTLDESRTVTSQ
                     FLIPRNFLQEDLLKLKSIIQERFLGHTVLDIHYKIRTEIPQIIQRYFTTTDNVIDLFE
                     HIFKEMFNENIVMAGKVNLLNFANLAAYQFFDQPQKVALEIREGLREDQMQNVRIADG
                     QESCLADLAVISSKFLIPYRGVGILAIIGPVNLDYQQLINQINVVNRVLTMKLTDFYR
                     YLSSNHYEVH"
     gene            complement(6150..6659)
                     /locus_tag="VQ862_001815"
     CDS             complement(6150..6659)
                     /locus_tag="VQ862_001815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001088691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2812 domain-containing protein"
                     /protein_id="HET3116115.1"
                     /translation="MNSRVEFRIFTIVDLDKKEEYLHEMHLKGWRYRTSRFGLFYFDQ
                     CQPDDVIYRIYDSRFLKKYKHELQDFRDRGWELIGAGSCSILRKSSSDLLPEDQVYMS
                     KGLKWEVMRSRLRSCTATFLGGLVVCTSLFREDLSMSFFLIFVLYAFLISYLIHGYFR
                     LKRKYRVDE"
     gene            7267..7567
                     /locus_tag="VQ862_001816"
                     /pseudo
     CDS             7267..7567
                     /locus_tag="VQ862_001816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818342.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit R"
     gene            7762..9600
                     /locus_tag="VQ862_001817"
     CDS             7762..9600
                     /locus_tag="VQ862_001817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000856786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HET3116116.1"
                     /translation="MKTPRYYQQIAINRTIETVARGQKRVMFVMATGTGKTFMAFQII
                     HRLRKAGLAKRVLFLADRNILVDQTMAEDFKPFEKVMTKITPKLLTAPEKLNSFEIYL
                     GLYQQLTGEDGTETHYQKFDKDFFDLIVIDEAHRGSAKENSNWRKIIDYFSSATQIGM
                     TATPKETKNASNTEYFGEPIYTYSLKQGIEDGFLAPYRVMRVNLDVDVDGYRPETGKV
                     DTNGQLIEDRYYGRKDFDKTIVIDDRTQRVAKFVSDYMKQSNARFDKTIVFCVDIDHA
                     ERMRAALVKENLDLVQEDYRYVMQVTGDNAEGKAQLDNFMDVNSNFPAIVTTSKLLTT
                     GVNAKTCRLIVLDSNIQSMTEFKQIIGRGTRLYPQKGKEFFTIIDFRNVTNLFADPDF
                     DGEPVKVLETGAKTVSGSTPGFVDEEGDPVEKYIVTDKQVTILNSTVQVLDENGKLIT
                     ESLTDYTRKNILGSYATLNDFITVWHTADKKKLILDELYKKGVYLDAIRESEGISEQE
                     IDDFDLLLKLAYGQKELTKTERINKLKQSGYLYKYSEEARAVLEILLNKYMDKGIGEL
                     ESIETLKLPEFQIYGGTFKIINTYFGDKKRYLQAIKELEQELFTVA"
     gene            9613..11076
                     /locus_tag="VQ862_001818"
     CDS             9613..11076
                     /locus_tag="VQ862_001818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000029054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent DNA methyltransferase"
                     /protein_id="HET3116117.1"
                     /translation="MSITSFVKRIQDITRNDAGVNGDAQRIEQMSWLLFLKIYDSREM
                     VWELEEDEYESIIPEELKWRNWAHAQNGERVLTGDELLDFVNNKLFKELKELEITSNM
                     PIRKTIVKSAFEDANNYMKNGVLLRQVINVIDEVDFNSPEDRHSFNDIYEKILKDIQN
                     AGNSGEFYTPRAATDFIAEVLDPKLGESMADLACGTGGFLTSTLNRLSSQRKTSEDTK
                     KYNTAVFGIEKKAFPHLLAVTNLFLHEIDDPKIVHGNTLEKNVREYTDDEKFDIIMMN
                     PPFGGSELETIKNNFPAELRSSETADLFMAVIMYRLKENGRVGVILPDGFLFGEGVKT
                     RLKQKLVDEFNLHTIIRLPHSVFAPYTGIHTNILFFDKTKKTEETWFYRLDMPDGYKN
                     FSKTKPMKSEHFNPVRDWWENREEILEGKFYKSKSFTPSELAELNYNLDQCGFPKEEE
                     EILNPFELIQNYQAERATLNHKIDNVLADILQLLEDK"
     gene            11076..>11265
                     /locus_tag="VQ862_001819"
     CDS             11076..>11265
                     /locus_tag="VQ862_001819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000187281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction endonuclease"
                     /protein_id="HET3116118.1"
                     /translation="MTPEQLKASILQRAMEGKLVPQNPNDEPASELLKRIKAEKEKLI
                     SEGKIKRDKKETEIFRGDD"
BASE COUNT         3435 a         2206 c         2212 g         3412 t
ORIGIN      
        1 catggcaagc cgacgctgac gtggtttgaa gaaatttttg aagagtatca ttcaccattt
       61 cacaactaaa tcgaagactt tctgccgtaa tgaaaacacc tgaaacagct tggtttcagc
      121 tgtccggaaa ctttaagact taggttcaaa gtttaggtat ggaacttcga aggaggtcgc
      181 taccgtccgt cattacttag gaaagtctta aaaaatctat aaagtaaaaa gagcccgaca
      241 gctctttttg tttatactca atgaaaatca aaaagcaaac taggaaacta gccacgggct
      301 gctcaaaaca ctgttttgag gttgtagata cgactcacat atatacggca aggcaacgct
      361 gacgtggttt gaagagattt tcgaagagta ttattctcca tcaaaggcat cttttatatg
      421 gtcaaagaag ccttttttct ttggatttac tttcaagtca ccagcagtcg cgaattcttt
      481 caaggctact ttttggcggt cgttcaagcc tgtcggtgtt acgacattaa cagtaacgta
      541 ttggtcacca actgcaccgc cacgaaggct cggtgccccc ttactacgta ggcggaattt
      601 cttaccagtc tgagttccct ctggaataac caattcaaca tcaccgtgaa cagttggaat
      661 atctactgta tcaccaagag ccgcttggac aaagttgagg ttgagattgt agaagatagt
      721 cgttccttca cgttcaaact tgtcgctagc ttctacagaa actactacat acaagtcacc
      781 ataaggtcca ccgttaaagc ctgcttcacc ttgaccagcg aggcgaattt gttgacctgt
      841 ttccacacca gcagggattt tcacatgtac gctatgagct tgtttctcat gacctgttcc
      901 atgacaggtt gtacatggat atttgatttc ttttcctcga ccgtgacaga catcacaggt
      961 tacttggcga cgcatcatac caagaggagt ctgcgtatcg acgttaatga caccagcgcc
     1021 atgacagcgt ccacaagtga ctggacttgt ccctggctta gcaccagagc cattacatgt
     1081 acgacagcca gcttcacgat gatacttaac ttccttctca gttccgaaga tagcttcttc
     1141 aaatgtcaaa ttgacacgat actggagatc atctccttgg cgaggagcgt ttggattgcg
     1201 cgaagaaccg cctccgccga agaaacttga gaaaatatcc tcaaaaccac cgaagccacc
     1261 tgccccattg aaaccaccga aaccaccagc tccaccaaaa ccaccattgg cgcctgcagc
     1321 accatactgg tcataggcag cacgtttttg gtcgtcactc aaagtctcat aggcttcttg
     1381 aacttccttg tacttgtcct cagcaccagg ctccttgttg atatctgggt gatatttttt
     1441 ggaaagctta cgataagcct ttttgatctc gtctgccgaa gcgttttttg acacccccag
     1501 acgatcataa aattcagtat tgttcataca agataccaag accgtaaaat tcgactgaaa
     1561 aataggaaat ctgacgctgg agcgacgctc ctagacagat ttctcttttt tccgagaatt
     1621 taggtcgggt tcaattcctt tcttttatat tgatgagata atactccagc cactcggccc
     1681 tatccctttt taccgaaaaa cagaggctgg gttgcaacct ctgtggttag attattcatt
     1741 tgaaataaaa atggttgtat tatctctagt agtaatcttc aaagaccttt tagctaaatc
     1801 aaactcaaat ttattatagt gtgggtcttg tgttttatat aggtgtaact cctgacatat
     1861 atgatccgaa aagtaaatca taacatcttt aaacacagaa gtgtagtcat atttactctt
     1921 accaacagct acttctgtaa attctttata aatgacattt ccatttcttt ccacagtcac
     1981 cagcatttct gttggattat aatccaaatt aaataattct tcaaaaaact ttatcttttc
     2041 atgataatct gcaatgtcag aaagattatt tttattaaca ctcataacac tagcccctta
     2101 tttttccgta aactctccgt ctacgacgtc atcgcctgcg tttcctgttg cttgtgcgcc
     2161 ttctgctcct tcttgagctt gttgcgctgc tgcggcttgt tcgtagagtt taacagcaag
     2221 tccttgagct ttttcgttca atgcttcaag tttcgctttc atgtcgtcca agttgttgtc
     2281 ttcttgagct ttcttaaggt catcaagggc agcttgggca gcgtcacgtt ctgcgtcgaa
     2341 gcctttacct tcagtttcct tgattgtctt ttcagtcgca aagattgctt ggtctacttc
     2401 attacgaagg tctacttctt ctttacgttt cttatcggct tcagcgtttg cttctgcatc
     2461 tttcatcatg cggtcgattt cttcgtcagt caaacctgag ttcgattgga tgacaatagt
     2521 ttgttctttt tgagttccaa ggtctttggc cttaacagac acgataccgt tcttgtcgat
     2581 gtcaaatgtt acttcgattt gaggaattcc acgaggtgca gctgggatat cagtcaattg
     2641 gaagcgtcca agagtcttgt tatctgctgc cattgggcgt tcaccttgaa gaacgtggat
     2701 atcaacggct ggttggttgt ctgctgctgt tgagaagact tgtgatttag atgttgggat
     2761 tgtagtgttg cgatcgataa gttttgtaaa tactccaccc attgtttcga taccaagtga
     2821 caatggcgtt acatcaagaa ggacaacgtc cttgacatca ccagtaatca caccaccttg
     2881 gatagccgca cccatagcaa ctacttcatc agggtttact gatttgtttg gttctttacc
     2941 agtttcagct ttaacagctt caacaacggc agggatacga gttgaaccac caacaaggat
     3001 aacttcgtcg atttctgaca agctcaaacc tgcatctgaa agggcttgac gaactggaac
     3061 ttttgtacgt tcaacaaggt cacgagtcaa atcatcaaat ttcgcacgag tcaaagtcat
     3121 ttccaagtga agaggtccag cctcacctgc agtgataaat ggcaagctga tttgtgttga
     3181 agttacacca gaaaggtctt tcttcgcttt ttcagccgca tctttcaaac gttgcattgc
     3241 catcttgtca gtagacaagt cgataccgtt ttctttcttg aattctgcta ccaagtggtc
     3301 aatgattttt tggtcaaagt cgtcaccacc aagtttgttg tcccctgcag ttgacaatac
     3361 gtcgaagaca ccgtcaccca attcaaggat agagacgtcg aatgtaccac caccaaggtc
     3421 aaataccaag attttttctt ctttatcagt cttgtccaaa ccataagcaa gagctgctgc
     3481 agttggttcg ttaacaatac gttctacttc aagaccagca attttaccag cgtcttttgt
     3541 tgcttgacgt tgagcgtcgt tgaagtaagc cggaactgtg ataacagctt tggttacttt
     3601 ctcaccaagg tagtcttcag cgtagccttt caagtattga aggatcatag ctgagatttc
     3661 ttgtggagtg tattcttttc catttgcaga aactttttca gaagttccca tcttagattt
     3721 gatagagata actgtatctg ggtttgtgac tgcttgacgt tttgcagcat caccaacgat
     3781 gatttctccg tttttgaatg agactacaga tggagttgtg cggtttcctt ctgggtttgc
     3841 gatgattttg ctttcagttc cttcaagaac tgcaactgct gagtttgttg tacctaagtc
     3901 aataccgata attttagaca tgtgtttttc tccttgttag ttaattttct atttttcttt
     3961 ttgatactct tcttaagtgg cgacgccgtc agagcttgac ttcgtcaatc tctttgacta
     4021 aactttgagc ctaaggtctc aaaatttgcg caaatagcgc cacggcgaag agtatcgtgt
     4081 ttggttcgct tcgctcacta ttacaaagcc aaacatattt tatctttctt catagtttat
     4141 tgtcgtttcg gacaagtttt ctattatgta aattgcgaca cgaagagtcg aaatcgattt
     4201 tatttcgacg acgagttagt aaggaagcta ggcaaacgcc atagcgattg ccgttttctg
     4261 acgagttgct ttagctaccg tcagaattgc cgaatcgaac acgccctaag ctctgagtaa
     4321 aaaagataga ttttcttgtg ttcatcgaac acttcgttaa tctcctattt ttactgcgag
     4381 ctttttacgg gctttgtatc ttagttatac accactacca ttgctgggcg taggatgcgg
     4441 tcatggagtt tgtagccttt ttgaaagact tgagcgatgg tatctactgg gtgttcatcg
     4501 tctgctggga gagtttggat ggccatatgg tagttatggt caaattcgcc atctgctgcg
     4561 atttcttcaa ttccttcttc tttcaaagcg tgaatcaagc tttcttgcac catccccaag
     4621 cccttcttca catcatctgt caaaccttca actgcaagtg cacgctcaag gttgtcaaga
     4681 gatggtaaga ttgcttttgc caagtcctgg ctacgataac gttgcaagtt ttgacgttct
     4741 tcattggcac ggcgttggat attttgcatt tctgcatgag cgcgaagata tttgttttcg
     4801 aactcatctg cacgttcatt tgccaagtcc aactcagact tttcaggagt tgtttcttca
     4861 gctgtttcca caacttcctc ttcttgaact tcttctactt cttcattttt tatatcttgg
     4921 gccatgttcg cctcctttaa tgatttcaat cttaatgtac ttcgtaatga ttactgctga
     4981 ggtagcggta aaaatctgtc aacttcatgg tcaaaacacg gttgaccaca ttgatttgat
     5041 tgattagctg ttggtaatcc agattaactg gaccgataat ggctagaatt ccaactcccc
     5101 gataaggaat gaggaactta ctactaatca ccgctaggtc agctaaacag gactcttgac
     5161 cgtctgcaat acgaacattt tgcatctgat cctcacgcaa cccctcacga atctccaagg
     5221 ccaccttttg cggttggtca aagaactgat aggctgctag attggcaaaa ttcaagagat
     5281 tgaccttgcc cgccatcaca atgttttcgt tgaacatttc cttaaagatg tgttcaaaga
     5341 gatcgatgac attatccgtt gttgtaaagt aacgctggat aatctgcgga atctccgtcc
     5401 gaatcttgta gtgaatatct aaaacggtgt gaccgaggaa acgttcctga atgatgctct
     5461 tcagtttcag caaatcctcc tgcaagaagt tccttggaat cagaaactga ctagtaaccg
     5521 ttcgcgactc gtctagggta aataccgcca aggctgtatg ttgccccaaa acaacgatat
     5581 caaaggctgt caaacgttgc ctgctcggct caacatccag tgccactacc gtacagccac
     5641 tcaggtctgt tagcaagtta gcagcctctt gcagaatatc ctccaatttg aagaattcct
     5701 gatcaaaggc tttgacaatc tcatatacct cattttcagc cagccggtga aaatccagtg
     5761 agtgtttcac atagtactga aaaccagcaa cacttggcat ccgaccgctt gaagtatgag
     5821 ccttctcaag caacccttgt ttttctagtt ccgccatgtc attacgaatg gttgcactgc
     5881 tagagttaat agactcttgc aaggcttttg atccgacagg ttcgtgcgtt ttggtaaaga
     5941 tgtcaataat cagatttaaa atatcctgct gacgctctgt aaccatctca tcactcctct
     6001 ctgtctgatc aattagcact caatgcatcc aagtgctaac ttatgattct attatacacc
     6061 cttagaagag aatgtcaaga caaaaactca aaaaattagc actcttttat caagagtgct
     6121 aaaaatcaat ctgaagacct agaaccttgc tattcatcta ctcggtattt cctttttagt
     6181 ctgaaataac catgaattag ataagaaatc agaaaagcat ataaaacaaa aataagaaag
     6241 aaagacatag aaagatcctc tctaaacaaa ctcgtacaaa caacaagacc acctaagaaa
     6301 gtagctgtac aggaacgaag tctagatcgc ataacttccc atttgagccc cttactcata
     6361 tagacttgat cctctggaag taaatcagaa gacgatttac gaagaatcga acaagaacct
     6421 gctcctatca attcccaacc tctatctcta aaatcttgca gttcatgctt atatttttta
     6481 agaaatctag aatcatagat acggtagatg acatcgtctg gttgacattg gtcaaaatag
     6541 aacaaaccaa aacgactcgt tctatacctc caacctttca aatgcatctc atgtaaatat
     6601 tcttctttct tgtccaaatc aacaatggtg aaaatccgaa attctactct gctattcatt
     6661 gtcttacccc aaaattagaa aacatgccta gcgttattta ttagataatt ctttccactt
     6721 ttgactcaat ctccaaaaaa tataagaaat ctgaatcgca aaaactatca ataaaaccca
     6781 atctattatg aaaatcaaaa acacttccca actgaaagaa ctacctccag tgacaaactt
     6841 tgagaaaaac ggtagtagag ctaaaaagag aagcaaaata ggaagcatcc gcattgttaa
     6901 aatccgtttg gcataaaaaa atctttattt aaacgaaaat attatggcaa aatttacgcc
     6961 agtttttgaa cggctgatgt agatatttta tactttcaaa atgtttaaat gtgattattt
     7021 atttttgaaa aatagctcac cagcccgact gaaagtgctt atagaatgat aataagtcgc
     7081 ctgccgaaaa cagcggaaaa tagcggtgtt atgcggagat aatctgacgc gatgcgaaag
     7141 tatattgcat acttattttc aacaatttag cagagtattt ttataagtgt gatataatag
     7201 aagtataatt tgttctgata gtttatttta tggagaagta gatttttaga atgcggaggg
     7261 ttcaatatgg ttgagtttat aaagtctaag aaagaaatga gtgaggagga tattaaagca
     7321 aatttcatca ctcctgctat tgtatccaaa ggatggaaaa atggtgagca tatcgcttac
     7381 gaagaatact tcactgatgg tcgaattgag gttagaggag ataaggctcg tcgtaaagaa
     7441 ggaaaaaaat cagactattc actgtattac caatttggaa ctcgaattgc aattgttgag
     7501 gcaaaggata ataaacacag cgttcgagca ggattacaac aagctattga atatggagag
     7561 attttagatg ttccatttgt ttattcttca aatggtgatg gctttattga acacgaccgt
     7621 atcacgagag aagaacgtga gctggagtta gacgaattcc ctactcgtga agaattattt
     7681 tctcgtatga cgaaggaaaa aggattgacg tacgaaatta cagaagctat ctaaactcca
     7741 tactatacag acgccttctc aatgaaaacg ccacgctatt atcagcaaat agctatcaac
     7801 cgtactattg aaacagttgc cagaggacaa aaacgagtaa tgtttgtgat ggcaacagga
     7861 acggggaaaa cgttcatggc ttttcaaatt attcatcgcc ttcgaaaagc tggtttggct
     7921 aaacgagttt tattcttagc ggatagaaac atcttagtag accaaacgat ggctgaagac
     7981 tttaagccat tcgaaaaggt aatgacgaaa attacaccaa aacttttgac tgctcctgaa
     8041 aaattaaatt cttttgaaat ttatctaggg ctttatcagc aactaactgg tgaagatgga
     8101 actgaaacac attatcaaaa atttgacaaa gacttctttg atttaatcgt aattgatgaa
     8161 gcgcaccgtg gttcagctaa ggaaaacagt aactggcgta agataattga ttatttcagt
     8221 tctgcgacac agattgggat gaccgctact cctaaagaaa ccaagaatgc ttccaatacg
     8281 gaatactttg gtgagccaat ctatacttat agtttaaaac agggaatcga ggatggtttt
     8341 ttggctccat atcgtgttat gagggttaat ttagatgtgg atgtggatgg ttatcgtcca
     8401 gaaactggaa aagttgatac taacggacaa ttaatagaag ataggtacta cggcaggaaa
     8461 gattttgata aaaccattgt cattgatgat agaacgcaaa gagttgccaa gtttgtttct
     8521 gattatatga agcaaagcaa tgcacgattt gataaaacaa ttgttttttg tgttgatatt
     8581 gaccatgccg agcgaatgcg tgctgcactt gtaaaagaga atctagactt agtccaagaa
     8641 gactatcgtt atgtcatgca agtaactggt gacaacgctg aaggaaaagc tcaactggat
     8701 aactttatgg atgtcaattc taattttccc gctattgtaa caacgtctaa attattaacg
     8761 acaggagtta atgctaaaac atgtcgtttg attgttttag actctaatat ccaatccatg
     8821 actgaattta aacaaattat tggtcgtggc acacgtcttt atcctcaaaa ggggaaagaa
     8881 ttttttacga ttattgattt tcgaaatgtt accaatttgt ttgctgaccc tgattttgat
     8941 ggtgagccag tgaaggtgct ggaaacaggt gcgaaaacag tcagtggttc cacgcccggt
     9001 ttcgtagatg aggaaggtga cccagtagaa aaatatatcg ttacagacaa gcaggttacc
     9061 attcttaatt ctactgttca agtattggat gaaaacggga aactgattac cgaaagcctg
     9121 accgactaca ctcggaagaa tatcttaggt agctacgcca ctttgaacga ttttatcaca
     9181 gtttggcata cggcggataa aaagaagctt atcttagacg aactttataa aaaaggagtt
     9241 tatctagatg ctattcgaga gtcggaggga atatcagaac aagaaatcga tgattttgat
     9301 ttactcctaa aacttgccta tggtcaaaaa gaattaacca aaacggaacg tatcaataaa
     9361 ctcaaacaaa gcggatattt atataaatat agtgaggaag cgcgtgctgt tttggaaatt
     9421 ttactgaaca aatacatgga taaaggtatt ggagaactcg aaagcattga aacattaaaa
     9481 cttccagaat ttcagatata tggtggaacc ttcaaaatca tcaatactta ttttggagat
     9541 aaaaaacgat atttacaagc aattaaagaa ttggagcaag agctatttac agtagcttaa
     9601 tgaaaggaaa gtatgtcaat tacatcattt gtaaaaagaa ttcaagatat cactcgaaac
     9661 gatgctggtg ttaatggtga tgctcaacgt attgagcaaa tgtcttggtt attattctta
     9721 aaaatttatg atagccgtga aatggtttgg gaattagaag aagacgagta tgagtcaatt
     9781 atcccagagg aattaaaatg gcgaaattgg gctcatgctc aaaatgggga acgggtattg
     9841 acaggcgatg aattacttga ttttgtcaat aacaagttat tcaaagagtt gaaagagctt
     9901 gaaataactt caaatatgcc tattcgaaaa acgattgtta aatcagcttt tgaagatgcg
     9961 aacaactata tgaaaaatgg cgtcttgtta cgccaagtca tcaatgttat tgatgaagtt
    10021 gatttcaata gccctgaaga tcgtcattcg tttaatgata tttacgaaaa aattcttaaa
    10081 gatattcaaa atgctgggaa ctcaggagaa ttttatacgc cacgtgcagc gactgatttt
    10141 attgccgaag ttcttgaccc aaaacttgga gaatcaatgg cagaccttgc ttgcggaaca
    10201 ggaggcttct tgacttcgac tctgaaccgt ttaagtagtc aacgtaaaac tagtgaagat
    10261 accaaaaaat ataatacagc tgtttttggt attgaaaaga aagcatttcc tcatctttta
    10321 gcagttacaa atctgtttct tcacgaaatt gatgacccta aaattgttca tggaaatact
    10381 ttggagaaaa atgttcgtga atatacggat gatgaaaaat ttgacattat tatgatgaat
    10441 ccaccttttg gagggtcaga attagaaaca ataaaaaata actttccagc agaattacgg
    10501 agttctgaaa cagctgattt atttatggct gtcattatgt atcgtttgaa agaaaatggt
    10561 cgtgttggag ttattttacc tgatggtttt ctatttggtg aaggtgtaaa aactcgcttg
    10621 aaacaaaaac tggtagatga gttcaacttg catacgatta ttaggttgcc tcatagtgtc
    10681 tttgcaccgt atacaggaat ccatacgaac attcttttct ttgataaaac aaagaaaaca
    10741 gaagaaactt ggttttatcg tttagatatg ccagatggtt ataaaaattt ctcgaaaact
    10801 aagccgatga agtcagaaca cttcaatcct gttcgtgact ggtgggaaaa tcgtgaagag
    10861 attctggaag gtaagttcta caaatctaaa tcatttacac ctagtgaatt ggctgagttg
    10921 aattataatt tagaccagtg tggttttcca aaagaggaag aggaaatctt aaatcccttt
    10981 gagttgattc agaattatca agcggaaaga gcaactttaa atcataagat tgataatgta
    11041 ttagctgata ttttgcagtt gttggaggac aaataatgac accagaacaa cttaaagcaa
    11101 gtattctcca aagagcgatg gaagggaaat tagtgccgca aaatcccaat gacgaacctg
    11161 caagtgaatt attaaagaga attaaagctg aaaaagaaaa acttatcagt gaaggaaaaa
    11221 tcaaacgaga taaaaaggaa actgagatat ttcgtggtga tgatg
//
LOCUS       DAVBOD010000064        11085 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 640-05
            SAMEA1012484-rid20186543.denovo.064, whole genome shotgun sequence.
ACCESSION   DAVBOD010000064 DAVBOD010000000
VERSION     DAVBOD010000064.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012484
            Sequence Read Archive: ERR059358
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11085)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11085)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979948.1
            Genome Coverage       :: 595x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:03:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,266
            CDSs (total)                      :: 2,219
            Genes (coding)                    :: 2,091
            CDSs (with protein)               :: 2,091
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 71 of 128
            Pseudo Genes (incomplete)         :: 50 of 128
            Pseudo Genes (internal stop)      :: 33 of 128
            Pseudo Genes (multiple problems)  :: 22 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11085
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012484-rid20186543.denovo.064"
                     /strain="NIG 640-05"
                     /db_xref="taxon:1313"
     gene            <1..116
                     /locus_tag="VQ862_001820"
     CDS             <1..116
                     /locus_tag="VQ862_001820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HET3116119.1"
                     /translation="TPEQAKQILEYGVRGIVVGGAITRPKEITERFVAGLK"
     gene            140..1063
                     /locus_tag="VQ862_001821"
     CDS             140..1063
                     /locus_tag="VQ862_001821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000687303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclically-permuted mutarotase family protein"
                     /protein_id="HET3116120.1"
                     /translation="MKIDVINHLDSPGLAGMICRRINNRILVYGGSYFPNNDPLKSSK
                     VQSNKIRVYDGKFNLLFEQDGQISPDKGITIEVENEIYYILGSSIYRITIDESVEEIC
                     IGDFDFQLESGYGCYYNGHLFFGFQESYLFNIETKELFKKSDFPVSGRGQGLSVKYQN
                     ELYYLGGANNEAYLDGYKYIFEKDKWEKLEFELPSSVLGASSIQINESDLLILGGFNE
                     IAYNKAVIDLATPGYREEYFSKGRDFFNWNRSLRILDLETGKVDIIANDERFALCGAG
                     FLKTDNGYYVVSGECSPGRRTSDILLLEEEM"
     gene            1145..2773
                     /locus_tag="VQ862_001822"
     CDS             1145..2773
                     /locus_tag="VQ862_001822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000724915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HET3116121.1"
                     /translation="MKKIVKLALTAAAVLIAVVGLVACSSGSKKSDSSESGKEKVFYL
                     SGLLQGTGDRIPYVWQNGDGLVPYLLYRTLLMADSKYEKSTPDLAKDWKKSDDEKTYE
                     FTLKDGLKWSDGEALTASDVEFSVKLALKASVINGIFPSTFTKIEGAKDFKDDKADKI
                     SGLTVDGNKVTFKLTAPVGNFEQMMTQFFILPKHKLESENPLELNNSSFWTAPVTSGM
                     YKVKEISAGNFLEYDKNENYENEKPKFDKVVFNYISDPVLALQDGKSYFYSTNKPQEI
                     SQLDAVSTLTKKPIDILFYRYFIANLAGVEGNGDSLIANPKVREAILYAINRDELAKS
                     VFSGIADVNNTGVPSSLEAHLKSANKFEYNPEKAKQLLKEAKYDNSRNLILAYYYKDQ
                     ASQDFMQAVSYQLNEVGIKNEVVQITSDATTGLFKTRKYDLAYKGLSSFGYETWYGEY
                     SSTNTNFKNITNGETSFDELSKKLSETSDVKERNKILASLQKLEQEKLLKLNLFTFKN
                     FLYLNTEKVLIPDDVQFGNPFYKFDYKFEKWDAK"
     gene            2882..3832
                     /locus_tag="VQ862_001823"
     CDS             2882..3832
                     /locus_tag="VQ862_001823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET3116122.1"
                     /translation="MKKYILKKVLFMIPMLLIISFLVFIALDLTPADPLTYMVSPDMA
                     SSAEQIEKLRQQLGLNDPVLVRYGRWLWQLLHGDFGYSIVNGNPISKIVGQALPATFE
                     LAFVSLIISTIVGIVIGVISAVKQNGIIDNVARFLAVIGTAIPQFFFGILILNFFAIQ
                     LRILPIGGRFTSGDFTFINRVEHLILPVMAMSIALVAALMRYTRNSMLDVFNADYVKT
                     ARAKGVPEWKVYFKHIFRNAMRPILVLLIFRLPMLIGGSVIIESVFSWPGIGSIILSS
                     VTAGDYPVIMITTLMISVVVLFASLLVDIMAAILDPRIRY"
     gene            3849..4700
                     /locus_tag="VQ862_001824"
     CDS             3849..4700
                     /locus_tag="VQ862_001824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000803875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET3116123.1"
                     /translation="MKPMPLWKRNLKKFYNNKLAFIGFICFMLILLACILAPLLTTYS
                     PDVVDLGSMNRPPSAKHILGTDKLGRDVFARILYGGRVSIQVGMYGAICGAVIGTVLG
                     GIAGYFGGKIDALLVRLAELFLTFPNMIVILLLSSIFGQGVFNLIFVFSVMGWMTTFR
                     MVRNEFMSLKQETYVDVCRAFGFSDSRIIFNNILRNAISPVIVSLSLNVAGFILSEAG
                     LSFLGVGVPSDIPTWGNIINAAKTADVIKNSWWLWLVPGSIITLFVLSINFIGDGLRD
                     IMDPKQQ"
     gene            4713..6695
                     /locus_tag="VQ862_001825"
     CDS             4713..6695
                     /locus_tag="VQ862_001825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001077263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3116124.1"
                     /translation="MNQTVLDVKNLKTEFITDKKAFPIIKDVNFTLERGKVLGIVGES
                     GCGKSVTVNTVLNLLPKNGRIAEGEITYFDEDKPIELQKLKQYGKEFRKLRGENISMI
                     FQDPMSALNPVYTIGNQITEVLHEHYDISKEEANKRAIEMLEKLGIHNAAERMNDYPH
                     QFSGGQRQRIVIAIAMVCNPDILIADEPTTALDVTIQAQILDLLDDLRKEHGTSIILI
                     THDLGVIAQIADEVAVMYAGEVVEVGTVAQIFDQPKHPYTRSLLRSIPNPENMDKKLH
                     VIQGSVPSISEISEKGCRFANRIPWLEKEHHEEEPQLHDLGDGHFVRCSCYKHFFFED
                     KEEETLAEKHVGNVVLEVKNIKKYYYPKKQLFKPLGSPLKALDDVSLELRKGTTIGIV
                     GESGSGKSTIAKSLMKLHEITDGEINIDLNGKTQNIYGIKRKEDLDFRKKVQMVFQDP
                     YASLNPTKKIYNSFDEPMIVHNIGNKEERFERMKESLKMVNVPVEYLERYPHEFSGGQ
                     RQRLCIARALCMKPEILILDEPVSALDLSVQAQVLNYLVEIQNKEDLTYVFISHDLGV
                     VKYMCDYLYVIHKGRIVEAGSREDIYNNPMHIYTKKLLAAIPEVDYHFKEALATKRKE
                     NEVEFKAQYHEFYDEDGRAYDLKQVSPTHFVALKPE"
     gene            6705..8114
                     /locus_tag="VQ862_001826"
     CDS             6705..8114
                     /locus_tag="VQ862_001826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000773463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3116125.1"
                     /translation="MKLNKKIYFFDKGIFNPYRMSNVKLKVNQAVKDKEIFFTEEKPW
                     EIRFDNSYPNVFFDDLAGVYRCYYSTFTDDEESEKYSLEERKERQYLPRAKRIVSLCY
                     AESKDGVNWVKPNLGITEFRGSTENNIIGHFLHGTSVFLDKHDADENRRYKMFTKIDY
                     GNGVHFIAVAFSKDGLHFDEYIKVPNFNPRADTHNHIIYDEALNRYVLITRTWRDSLR
                     LPCVSTSADFINWTPIQEILNVCDYENQIYSMPIFKRGDYILGLASVFHEGDQLNKNY
                     DTVDLQLTYSYRHVGWHYLNTDTPLIPRGKGQYGDGEFDCGCIYSSAPVTIGDRTYFY
                     YMGGNGQHTNFRETSLSRAYIEKDHFAYWDIKRPEYPGVLYTNGFIFLNDQVYLDADI
                     AAGGFVTIELFENNHTPMEITASLEKIEDGRYQVLFSEPLPRTQTRLKISFKNAKIYA
                     IEGNLDIFRIESDNALLRG"
     gene            8119..8607
                     /locus_tag="VQ862_001827"
     CDS             8119..8607
                     /locus_tag="VQ862_001827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000872894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidylglycerophosphatase A"
                     /protein_id="HET3116126.1"
                     /translation="MKYDLYDNCIELLKEREVTIEDMAALVIFSQQKYYPELTLDDAS
                     YAIQRVLKKREVQNVIMTGIELDKLAEAQKLSPEFQKIMEKDNPLYGIDEVIVLSILN
                     LYGSIAFTNYGYLDKLKPLILERLNENHEGVCNVFLDDIVGAIAAAACSKIAHNHASD
                     EI"
     gene            8895..9302
                     /locus_tag="VQ862_001828"
     CDS             8895..9302
                     /locus_tag="VQ862_001828"
                     /EC_number="3.5.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000216069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HET3116127.1"
                     /translation="MTVINKFVLMEQAKKVLKNAYFPYSKFPVGAAILFKDGKVITGA
                     NIENVSFGVTNCAERSAIFYGTSQGYRKGDILAIAVAGETEDYLPPCNICRQVMVEFC
                     EPDTLVFLLNGKGNILELRLEELVPYSFSSLEM"
     gene            9334..10251
                     /locus_tag="VQ862_001829"
     CDS             9334..10251
                     /locus_tag="VQ862_001829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrodipicolinate synthase family protein"
                     /protein_id="HET3116128.1"
                     /translation="MSDLKKYEGVIPAFYACYDDQGEVSPERTRALVQYFIDKDVQGL
                     YVNGSSGECIYQSVEDRKLILEEVMAVAKGKLTIIAHVACNNTKDSMELARHAESLGV
                     DAIATIPPIYFRLPEYSVAKYWNDISSAAPNTDYVIYNIPQLAGVALTPSLYTEMLKN
                     PRVIGVKNSSMPVQDIQTFVSLGGEDHIVFNGPDEQFLGGRLMGARAGIGGTYGAMPE
                     LFLKLNQLIADKDLETARELQYAINAIIGKLTSAHGNMYGVIKEVLKINEDLNIGSVR
                     SPLTPVTEEDRPVVEEAAALIRETKERFL"
     gene            10278..10472
                     /locus_tag="VQ862_001830"
                     /pseudo
     CDS             10278..10472
                     /locus_tag="VQ862_001830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398633.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
     gene            complement(10622..>11085)
                     /locus_tag="VQ862_001831"
     CDS             complement(10622..>11085)
                     /locus_tag="VQ862_001831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000547411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET3116129.1"
                     /translation="YAMFDKEQKRGYKQSARNLANWHYNDKEDSYTHPDGWYYRFHHT
                     KYQKTQTDFQQKIKVYYADEPESAPQKGLYMNERYQNLKAKECQALLSPQGRQIFAQR
                     KIDVEPVFGQIKACLGYKRCNLRGKRQVRIDMRLVLMANNLLKYNKRTTQN"
BASE COUNT         3693 a         1665 c         2115 g         3612 t
ORIGIN      
        1 atacaccaga acaagccaaa caaatccttg aatatggagt gcgaggaatc gttgttggtg
       61 gcgctattac tagaccaaaa gagattacag aacgttttgt agcgggatta aaatagcatg
      121 ccagagtaag aggtgtaata tgaaaattga tgttataaat catttagact caccaggatt
      181 agctgggatg atttgtagac ggattaataa tagaatttta gtttatggag gtagttattt
      241 cccaaataac gatcctttaa aaagttcaaa agttcaatca aataaaatta gagtttatga
      301 cgggaaattt aatcttctat ttgaacaaga tggacagatt tctccagata aaggaataac
      361 gattgaagtt gaaaatgaaa tctattacat tctaggctcg agcatttatc gtattacgat
      421 tgatgaaagt gtagaagaaa tctgtatcgg ggattttgat ttccaactag agagtggtta
      481 tggttgttat tataatggcc acttattctt tggatttcag gaaagttatc tgttcaatat
      541 tgagactaaa gaacttttta aaaaatctga cttcccagtt tctggtagag gacaaggttt
      601 atcagtcaaa tatcaaaatg aattgtatta tttaggtgga gcgaacaatg aagcttattt
      661 agatggatac aaatatattt ttgaaaaaga taagtgggaa aaacttgagt ttgaattacc
      721 aagttcagtt ttaggagcgt caagtataca aataaatgaa agtgatttat taatccttgg
      781 tggctttaat gaaattgctt ataataaagc agttattgat ttagcaaccc ctggctatag
      841 ggaagaatac ttttctaagg gaagagattt ctttaattgg aatcgtagct tgcgaatact
      901 agatttagag acaggtaagg tcgatattat tgcaaacgat gagcgttttg ctctttgtgg
      961 ggcaggattt ttaaaaactg ataatggata ttacgttgtt agtggggaat gtagcccagg
     1021 aagacgtact tctgacatac ttttgttaga ggaggaaatg taacgaagag tttaaatttt
     1081 taattactgc aatacttact taatcacata aataattact taatacaaat aaaggagtat
     1141 taaaatgaaa aaaattgtta aattagcttt aacagctgca gcagttttaa tagctgtagt
     1201 aggattggtt gcttgtagtt cgggaagcaa aaaatctgat tcttcagagt ctggaaaaga
     1261 aaaagtattc tatttatcag gtttgcttca aggaactgga gatcgtatcc cttacgtttg
     1321 gcaaaatggt gatggtttag ttccatattt gttataccgt acactgttaa tggcagattc
     1381 aaaatatgaa aaatcaactc cagatttagc taaagattgg aaaaaatctg atgatgaaaa
     1441 aacttatgaa tttacactta aagatgggtt gaaatggtct gatggagaag ctttgacagc
     1501 ttccgatgtg gaattcagtg ttaaattagc attgaaagct tcagtaatta atggaatttt
     1561 cccttcaaca ttcacaaaaa ttgaaggagc taaagatttc aaagacgata aagcagataa
     1621 aatttctggt cttacagttg atggaaataa agtaacattt aaacttactg ctccagttgg
     1681 taactttgag caaatgatga ctcaattctt tattcttcca aaacataaat tagagtctga
     1741 aaatcctctt gaattaaata atagctcatt ttggacagct cctgttacaa gcggtatgta
     1801 caaagtaaaa gaaattagtg caggtaattt cttagagtat gacaaaaatg aaaactatga
     1861 aaatgaaaaa ccaaaatttg ataaagtagt attcaactat atttcagatc cagttttagc
     1921 attgcaagat ggtaaatcat acttctattc aacaaacaaa cctcaagaaa ttagtcagtt
     1981 ggatgctgta tctactttaa ctaaaaaacc aattgatata ctattctatc gctactttat
     2041 cgctaactta gcaggtgttg aaggtaatgg agattccttg attgctaatc ctaaagttag
     2101 agaagctatt ctatatgcaa ttaatcgtga tgaattagct aaatctgtat ttagtggaat
     2161 tgcagatgtt aataatactg gtgttccttc aagcttagaa gctcatctga aatcagcaaa
     2221 taaatttgaa tataatccag aaaaagcaaa acaacttctt aaagaagcta aatacgataa
     2281 tagcagaaat ctaattttag cttattacta taaagatcaa gcctctcaag atttcatgca
     2341 agcagtaagt tatcaattga atgaggttgg aatcaagaac gaagttgtcc aaattacttc
     2401 tgatgcaaca acaggattgt tcaaaacacg taaatatgac ctagcttata aaggattatc
     2461 atcatttggt tatgaaactt ggtatggtga atatagttca acaaatacta actttaaaaa
     2521 tattacaaat ggcgaaacaa gttttgatga gttgagcaaa aaattgtctg aaacttctga
     2581 tgtaaaagaa agaaacaaaa ttttagcaag tctacaaaaa ttagaacaag aaaaactatt
     2641 gaagttaaac ttattcacat ttaaaaactt cttgtattta aatactgaaa aagttttaat
     2701 tcctgacgat gttcaatttg gtaatccatt ctataaattt gattacaaat tcgaaaaatg
     2761 ggatgctaaa taaaatcgtt taaaattatc agtgattaag tttgataatc ttttaggagt
     2821 gtagagatgc tgtttattga atcatgtatc tctcactctt gttttttcag gagaaattaa
     2881 aatgaaaaaa tatattctaa aaaaagtatt attcatgatt cctatgttgt tgattattag
     2941 ctttttagta ttcattgcac tagatttaac accagcagat ccattgacat atatggtatc
     3001 tccagatatg gctagtagtg cagaacaaat cgaaaagcta agacagcaat taggtttaaa
     3061 tgatccagta ttagttcgct atggaagatg gctttggcaa ttactccatg gtgattttgg
     3121 atacagtatt gtaaatggta acccaatttc caaaattgta ggacaagcat tgcctgcaac
     3181 ttttgaatta gcttttgtgt cattaattat ttcaacaatt gttggtattg taattggggt
     3241 tatatcagcc gttaaacaaa atggtattat cgataatgtt gctcgttttc tagctgttat
     3301 cggaactgcg attccacaat ttttctttgg tattttaatt ttaaacttct ttgcaattca
     3361 gttaagaatt ttacctattg gtggtagatt taccagtgga gattttacat ttattaatag
     3421 agttgaacac ttaattctac cagtaatggc tatgtcaatt gcattggtag ccgctttaat
     3481 gagatacaca cgtaattcta tgttggatgt ttttaatgca gattatgtta aaacagctcg
     3541 tgcaaaaggt gttcctgaat ggaaagttta ttttaaacac atatttagaa atgctatgcg
     3601 accaatttta gtgttattga ttttccgtct accaatgtta attggtggat cagtaattat
     3661 cgagagtgtc ttttcttggc ctggaattgg ttctatcatc ctatctagtg taacagcagg
     3721 tgactatcct gtaattatga ttaccacatt aatgatttct gtcgtagtgt tatttgctag
     3781 tctacttgta gatattatgg ctgcaatatt agacccacgt attcgttatt aggaaggagg
     3841 tcaatgttat gaaacctatg cctttatgga aaagaaattt gaaaaaattc tataataaca
     3901 aattggcctt tatcggcttt atatgcttca tgctaattct attagcatgt attctagcac
     3961 ctttattgac aacctattct ccagatgttg ttgatttagg atctatgaac cgtcctcctt
     4021 cagcaaaaca cattctggga acagataaac taggtcgtga cgtatttgct cgaatcctat
     4081 atggtggtcg agtttcaatt caagtaggga tgtatggagc gatttgtgga gcggttattg
     4141 gtactgtact tggtggtatt gctggatatt ttggtgggaa aattgatgct cttctagttc
     4201 gtctagcaga attattctta acattcccga atatgattgt cattctcttg ctttcaagta
     4261 tttttggaca aggtgtattc aatcttatct tcgtattctc agtaatgggt tggatgacaa
     4321 cgttccgaat ggttcgtaat gagttcatgt ctttgaaaca agaaacatat gtggatgtat
     4381 gtagagcttt tggtttttct gacagtcgaa ttatctttaa taatatttta agaaatgcta
     4441 tctcaccagt aattgtatcg ttgtctttaa acgttgctgg tttcattctc agtgaggcag
     4501 gtcttagttt cttaggagta ggtgttcctt ctgatattcc tacttgggga aatatcataa
     4561 atgctgccaa aacagccgat gttattaaaa atagttggtg gctgtggtta gttccagggt
     4621 caatcattac tcttttcgtt ctttctatca actttattgg tgatggatta cgagatataa
     4681 tggatccgaa acaacagtag gaggttgaca aaatgaatca aacagtttta gatgtaaaaa
     4741 acttaaaaac tgaattcatc actgataaaa aagcatttcc gattattaaa gatgtaaact
     4801 tcactttgga aagagggaaa gttttaggga ttgttggtga atctggatgc ggtaagagtg
     4861 taacagtgaa tacagtgtta aacttattac ctaaaaatgg acgcattgct gaaggtgaaa
     4921 tcacatattt cgatgaagat aagccgatag agcttcaaaa attaaagcaa tatggtaaag
     4981 aatttcgaaa gttacgtggt gaaaacatat caatgatttt ccaagatcca atgtctgcat
     5041 tgaatccagt atatacaatt ggtaatcaaa ttactgaagt ccttcatgaa cattatgaca
     5101 tttctaaaga ggaggcaaat aaacgtgcta tagaaatgtt agaaaaactt ggaattcata
     5161 atgctgcaga acgcatgaat gactatccac accaatttag tggagggcag cgtcaaagaa
     5221 tagtcatagc gattgcaatg gtatgtaatc cagatattct aattgcagat gaaccaacaa
     5281 ctgcccttga tgtaacaatc caagcacaaa tacttgattt acttgatgat ttacgtaaag
     5341 agcatggaac ttctattatc ttaattactc acgatttagg cgttattgct caaattgcgg
     5401 atgaagttgc agtgatgtat gctggtgaag tcgttgaagt tggaactgta gctcagatct
     5461 ttgatcaacc taaacacccg tatactcgtt ctctattaag atctattcct aatcctgaaa
     5521 atatggataa aaagctacat gttatccagg ggagcgtacc ttcaatttct gaaatatctg
     5581 aaaaaggatg cagattcgca aatcgtattc catggttaga aaaagaacat catgaagaag
     5641 aacctcaatt gcatgattta ggtgacggac attttgtaag gtgttcttgc tataaacatt
     5701 tctttttcga agataaggaa gaagaaacat tagcggaaaa acatgtaggt aatgttgttt
     5761 tagaagtaaa aaatattaaa aagtactact atcctaagaa acaactattc aagccactag
     5821 gttctccgtt gaaagcactt gatgacgtat ctctagagtt aagaaaagga actactattg
     5881 gtatcgtagg agagtctgga agcggtaaga gtacgattgc gaaatcatta atgaaactcc
     5941 atgagattac agatggtgaa atcaatattg atttgaatgg gaaaactcaa aatatttatg
     6001 gaattaaacg taaggaagat ttggatttcc gtaagaaagt tcaaatggta ttccaagatc
     6061 cttatgcatc attgaaccca actaagaaaa tttataattc atttgatgaa ccgatgattg
     6121 tccataatat tggaaacaaa gaggaacgct ttgaacgtat gaaagaatcc ttgaagatgg
     6181 taaacgtgcc agttgagtac ttggagcgtt atcctcatga attttcaggc ggacaacgtc
     6241 aacgtttatg tattgctcgt gccctttgta tgaaaccaga aattttaatt ttagatgaac
     6301 ctgtttcagc attagatcta tctgtacaag cgcaagtttt gaattatctt gttgaaatcc
     6361 aaaataaaga agatttgact tatgtattta tttctcatga cctaggtgtt gtgaaataca
     6421 tgtgtgacta tctatatgtt attcataaag gacgtattgt agaagctggt tctcgagaag
     6481 atatctacaa taacccaatg catatttaca ctaaaaaact attagctgct attccagaag
     6541 ttgattatca cttcaaagag gcattggcaa caaaacgtaa agaaaatgaa gttgaattta
     6601 aagcacagta ccatgaattt tatgatgaag atggccgtgc ttatgatctt aagcaggttt
     6661 caccaacaca ttttgtagcg ttaaaaccag aataggtggt aaatatgaaa ttaaataaaa
     6721 aaatatattt ctttgataaa ggaattttta atccttatcg aatgagtaat gtaaaattaa
     6781 aagttaatca ggcagtaaag gataaagaaa ttttcttcac tgaggaaaaa ccatgggaaa
     6841 ttcgttttga taacagttat ccaaatgttt tctttgatga tttagcaggt gtttatcgtt
     6901 gctactattc tacatttact gatgatgagg agtctgaaaa atactcttta gaggagcgta
     6961 aggaacgtca atatctacct cgtgcgaagc gtattgtttc actttgttat gctgaaagta
     7021 aagatggtgt taactgggtg aaaccaaatc taggtattac agaatttcga ggatcaactg
     7081 aaaataatat tatcggacat tttttacatg gtacatctgt ttttctagat aaacatgacg
     7141 cagatgaaaa tcgtcgttat aaaatgttta caaagattga ttacggtaac ggtgttcatt
     7201 ttattgctgt agcattttca aaagatggtc tacactttga tgaatacatt aaagtaccaa
     7261 acttcaatcc acgtgcagac actcataacc atatcatata tgatgaagca ttaaatcgct
     7321 atgtgctaat tactcgtact tggagagatt cattgcgctt gccgtgtgta tctacgagtg
     7381 ctgatttcat taactggact ccaattcaag aaattttgaa tgtctgtgat tatgaaaatc
     7441 aaatttattc tatgcctatt tttaaacgtg gcgattatat actaggttta gcttcagttt
     7501 tccatgaagg agatcaactg aacaagaatt acgatacagt ggaccttcaa ttgacttata
     7561 gttatcgtca tgttggttgg cattatctaa acactgatac tccacttatt cctcgtggta
     7621 aaggtcaata tggtgatgga gaatttgact gtggatgtat ctattcttct gcaccagtta
     7681 ctatcggtga ccgtacttat ttctactaca tgggaggaaa tggacaacat acaaacttcc
     7741 gtgaaacaag cttgtctcgt gcttatattg agaaagatca ctttgcatat tgggatatta
     7801 aacgtccaga atatccaggt gttttgtata ccaatggatt tattttcctc aatgatcaag
     7861 tttaccttga tgcagatatt gcagctggag gctttgtaac aattgaattg ttcgagaata
     7921 atcacactcc aatggaaatt acagcttccc ttgaaaaaat agaagatggt cgctatcaag
     7981 tgttattcag cgaaccttta cctcgaactc aaactcgact gaaaattagc tttaaaaatg
     8041 ctaaaatcta cgcaatcgaa ggaaatttag atattttcag aattgaatca gacaatgctc
     8101 tattgagggg gtaagattat gaaatatgat ttatatgata attgtattga acttctaaaa
     8161 gaacgcgaag ttacaattga agatatggca gcgttagtaa tattttcaca acaaaaatat
     8221 taccctgaat taactcttga cgacgcttca tatgcaattc aacgtgtact aaaaaaacgt
     8281 gaagttcaga atgtaattat gacaggaatt gagttagata agttagctga agcacaaaaa
     8341 ctatctccag aatttcaaaa gattatggag aaagataatc cattgtatgg gattgatgaa
     8401 gtaatcgtct tatcgatatt gaatttatat ggttctattg cctttacaaa ttatggctat
     8461 ttagataaat taaaaccact gattttagaa agattgaatg agaatcacga aggtgtttgt
     8521 aatgtatttc tagatgatat tgttggtgca atagccgcag cagcatgtag taaaattgca
     8581 cacaatcatg ctagtgatga aatataacta ttgaatttag tatcgtaaat aataaagcgt
     8641 ttggtttcta gattattgtc attcaaattg gataatgata aatctagaaa ccaaatatat
     8701 tttccgcata aaatgaggga ttatatatct cactttttta caattgtata gtggattaaa
     8761 actagaatag tgcatctcta cttctaaaac attgttagaa atcgatttga ctgtcctgat
     8821 tgatttgtac tgttcttatt tcattttact ataatttagt gtgagtaaaa tataataata
     8881 aaggagttaa aacaatgaca gtaattaata aatttgtttt aatggagcaa gcaaaaaaag
     8941 ttttaaaaaa tgcttacttt ccgtattcca aatttcctgt aggtgcagca attttattta
     9001 aagatggtaa agtaattaca ggagcaaata tagaaaatgt atcgtttggt gtaactaact
     9061 gtgcagaacg tagtgctatt ttttatggga cttctcaagg atatagaaaa ggagatattc
     9121 ttgcgattgc tgttgcaggt gaaactgaag actacttacc accatgcaac atttgtcgtc
     9181 aagttatggt agaattttgt gagcctgata ccttagtctt tctattaaat ggtaagggaa
     9241 acatacttga attgcgatta gaggaattag tcccatattc gttctcaagt ctagaaatgt
     9301 aattacgtag tatgaaataa ggagaaaaaa acaatgtcag atttgaaaaa atacgaaggt
     9361 gtcattccag ccttctacgc atgttatgat gatcaaggag aagtaagccc agaacgtacg
     9421 cgtgccttgg ttcaatactt cattgataaa gatgttcaag gtctttatgt caatggttct
     9481 tctggtgaat gtatctacca aagcgttgaa gatcgcaagt tgattttgga agaagtcatg
     9541 gcggtagcca aaggtaaatt gaccattatt gcccatgttg cttgcaataa tactaaagac
     9601 agtatggaac ttgctcgcca tgctgaaagc ttgggagtag atgctattgc aacgattcca
     9661 ccaatttatt tccgcttgcc agaatactca gttgccaaat actggaacga tatcagttct
     9721 gcagctccaa acacagacta cgttatttac aacattcctc aattggcagg ggttgctttg
     9781 actccaagcc tttacacaga aatgttgaaa aatcctcgtg ttatcggtgt gaagaactct
     9841 tctatgccag ttcaagatat ccaaaccttt gtcagccttg gtggagaaga ccatatcgtc
     9901 tttaatggtc ctgatgagca gttcctagga ggacgcctca tgggggctag ggctggtatc
     9961 ggtggtactt atggtgctat gccagaactc ttcttgaaac tcaatcagtt gattgcggat
    10021 aaggacctag aaacagcgcg tgaattgcag tatgctatca acgcaatcat tggtaaactc
    10081 acttctgctc atggaaatat gtacggtgtc atcaaagaag ttttgaagat caatgaagac
    10141 ttgaatattg gatctgttcg ttcaccattg acaccagtga ctgaagaaga tcgtccagtt
    10201 gtagaagaag ctgctgcctt gattcgtgaa accaaggagc gcttcctcta atccataagg
    10261 aggtatttat gacgcactac gttgccaatc cagaggtggt cattctcggg ggtggcatca
    10321 tgggacaaga agctatcctc aaaccaaaga ttcgtgcagc cttgaaagaa gccttggttc
    10381 caagtttggc tgagaacaca agattagaat ttgctcatca tcaaaacact gctgatatgc
    10441 ttggagccta ctatcatttt aaaataaaat aaatttaata tttactttac taaattagtg
    10501 tattcttcct actttaatta gagaatgatt taagttctct ttaaaaatca aaagagtcta
    10561 ggataaaata gttctcaatc acaaaaaagc taaagatttc caattgtgga actctagctt
    10621 tttaattttg agtcgttctc ttattgtatt ttaggaggtt attggccata agtaccaatc
    10681 tcatgtcaat tctcacttga cgcttccctc tcagattaca tctcttgtaa cccaaacaag
    10741 cctttatctg cccaaagaca ggttccacat caatcttgcg ttgagcgaaa atctgtctac
    10801 cttggggaga taaaagcgcc tgacattctt tagctttcaa gttttgatag cgttcgttca
    10861 tatacagtcc cttttgaggg gctgattcag gttcgtcggc gtagtaaacc ttgatttttt
    10921 gttgaaagtc tgtctgtgtt ttctgatatt tggtatggtg aaaacgataa taccagccat
    10981 caggatgtgt atagctatcc tccttgtcat tatagtgcca attcgctaag tttctagctg
    11041 actgtttata gcctctcttt tgttccttat caaacatggc atatt
//
LOCUS       DAVBOD010000065        11007 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 640-05
            SAMEA1012484-rid20186543.denovo.065, whole genome shotgun sequence.
ACCESSION   DAVBOD010000065 DAVBOD010000000
VERSION     DAVBOD010000065.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012484
            Sequence Read Archive: ERR059358
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11007)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11007)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979948.1
            Genome Coverage       :: 595x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:03:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,266
            CDSs (total)                      :: 2,219
            Genes (coding)                    :: 2,091
            CDSs (with protein)               :: 2,091
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 71 of 128
            Pseudo Genes (incomplete)         :: 50 of 128
            Pseudo Genes (internal stop)      :: 33 of 128
            Pseudo Genes (multiple problems)  :: 22 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11007
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012484-rid20186543.denovo.065"
                     /strain="NIG 640-05"
                     /db_xref="taxon:1313"
     gene            complement(128..1759)
                     /locus_tag="VQ862_001832"
     CDS             complement(128..1759)
                     /locus_tag="VQ862_001832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004251733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na/Pi cotransporter family protein"
                     /protein_id="HET3116130.1"
                     /translation="MSINWQEILFHFLGGLGLFLYSIKTMGDGLQQAAGDRLRFYIDK
                     YTSNPFFGVLVGIGMTALIQSSSGVTVITVGLVSAGLLTLRQAIGIVMGANIGTTVTS
                     FLIGFKLGNYALPMLFIGAVCLFFTKNRTVNNIGRILFGVGGIFFALNLMSGAMAPLK
                     DLQVFKDYMIELSKNPVLGVFVGTGLTLLIQASSATIGILQNLYAGNLIDLQGALPVL
                     FGDNIGTTITAIIASLGANIAAKRVAGAHVAFNVIGTVVCVIFLVPFTVLIHWFEATL
                     NLAPEMTIAFAHGTFNITNTIVQFPFIGALAYFVTKIIPGEDEVVKYEPLYLDEHFIK
                     QAPSIALGNAKKELLHLGNYAAKAFDLSYKYIIDLDEKVAEKGHKTEEAINTIDEQLT
                     RYLIALSSEALSQKESEVLTNILDSSRDLERIGDHTEALLNLTDYLQRKNVEFSDAAL
                     KELEEVYRQTSDFIKDALDSVENNDIEKARSLVERHEAINKIERVLRKTHIKRLNKGE
                     CSTQAGVNFIDIISHYTRVSDHAMNLAEKVFAEQI"
     gene            2052..6992
                     /locus_tag="VQ862_001833"
     CDS             2052..6992
                     /locus_tag="VQ862_001833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000795197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacterial Ig-like domain-containing protein"
                     /protein_id="HET3116131.1"
                     /translation="MKNPFFERRCRYSIRKLSVGACSLMIGAVLFVGPALAEETAVPE
                     NSGANTELVSGESEHSTNEADKQNEGEHTRENKLEKAEGVATASETAEAASAAKPEEK
                     AGEVVAETPSAEAKPKSDKETEAKPEATNQGDESKPAAEANKTEKEVQPDVPKNTEKT
                     LKPKEIKFNSWEELLKWEPGAREDDAINRGSVVLASRRTGHLVNEKASKEAKVQALSN
                     TNSKAKDHASVGGEEFKAYAFDYWQYLDSMVFWEGLVPTPDVIDAGHRNGVPVYGTLF
                     FNWSNSIADQERFAEALKQDADGSFPIARKLVDMAKYYGYDGYFINQETTGDLVKPLG
                     EKMRQFMLYSKEYAAKVNHPIKYSWYDAMTYNYGRYHQDGLGEYNYQFMQPEGDKVPA
                     DNFFANFNWDKAKNDYTIATANWIGRNPYDVFAGLELQQGGSYKTKVKWNDILDENGK
                     LRLSLGLFAPDTITSLGKTGEDYHKNEDIFFTGYQGDPTGQKPGDKDWYGIANLVADR
                     TPAVGNTFTTSFNTGHGKKWFVDGKVSKDSEWNYRSVSGVLPTWRWWQTSTGEKLRAE
                     YDFTDAYNGGNSLKFSGDVAGKTDQDVRLYSTKLEVTEKTKLRVAHKGGKGSKVYMAF
                     STTPDYKFDDADAWKELTLSDNWTNEEFDLSSLAGKTIYAVKLFFEHEGAVKDYQFNL
                     GQLTISDNHQEPQSPTSFSVVKQSLKNAQEAEAVVQFKGNKDADFYEVYEKDGDSWKL
                     LTGSSSTTIYLPKVSRSASAQGTTQELKVVAVGKNGVRSEAATTTFDWGMTVKDTSLP
                     KPLAENIVPGATVIDSTFPKTEGGEGIEGMLNGTITSLSDKWSSAQLSGSVDIRLTKP
                     RTVVRWVMDHAGAGGESVNDGLMNTKDFDLYYKDADGEWKLAKEVRGNKAHVTDITLD
                     KPITAQDWRLNVVTSDNGTPWKAIRIYNWKMYEKLDTESVNIPMAKAAARSLGNNKVQ
                     VGFADVQAGATITVYDNPNSQTPLATLKSEVGGDLASAPLDLTNQSGLLYYRTQLPGK
                     EISNVLAVSVPKDDRRIKSVSLETGPKKTSYAEGEDLDLRGGVLRVQYEGGTEDELIR
                     LTHAGVSVSGFDTHHKGEQNLTLQYLGQPVNANLSVTVTGQDEASPKTILGIEVSQKP
                     KKDYLVGDSLDLSEGRFAVAYSNDTMEEHSFTDEGVEISGYDAQKTGRQTLTLRYQGH
                     EVNFDVLVSPKAALNDEYLKQKLAEVEAAKNKVVYNFASPEVKEAFLKAIEAAEQVLK
                     DHEISTQDQVNDRLNKLTEAHKALNGQEKFKEEKTELDRLTGEVQELLDAKPNHPSGS
                     ALAPLLEKNKVLVEKVDLSPEELATAKQSLKDLVALLKEDKPAVFSDSKTGVEVHFSN
                     KEKTVIKGLKVERVQASAEEKKYFAGEDAHVFEIEGLDEKGQDVDLSYASIVKIPIEK
                     DKKVKKVFFLPEGKEAVELAFEQTDSHVIFTAPHFTHYAFVYESAEKPQPAKPAPQNK
                     VLPKPTYQPASDQQKAPKLEVQEEKVAFHRQEHENAEMLVGEQRVIIQGRDGLLRHVF
                     EVDENGQRRLRSTEVIQEAIPEIVEIGTKVKTVPAVVATQEKPAQNTAVKSEEASKQL
                     PNTGTADANEALIAGLASLGLASLALTLRRKREDKD"
     gene            7082..8278
                     /locus_tag="VQ862_001834"
     CDS             7082..8278
                     /locus_tag="VQ862_001834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001096748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate kinase"
                     /protein_id="HET3116132.1"
                     /translation="MAKLTVKDVDLKGKKVLVRVDFNVPLKDGVITNDNRITAALPTI
                     KYIIEQGGRAILFSHLGRVKEEADKAGKSLAPVAADLAAKLGQDVVFPGVTRGAELEA
                     AINALEDGQVLLVENTRYEDVDGKKESKNDPELGKYWASLGDGIFVNDAFGTAHRAHA
                     SNVGISANVEKAVAGFLLENEIAYIQEAVETPERPFVAILGGSKVSDKIGVIENLLEK
                     ADKVLIGGGMTYTFYKAQGIEIGNSLVEEDKLDVAKALLEKANGKLILPVDSKEANAF
                     AGYTEVRDTEGEAVSEGFLGLDIGPKSIAKFDEALTGAKTVVWNGPMGVFENPDFQAG
                     TIGVMDAIVKQPGVKSIIGGGDSAAAAINLGRADKFSWISTGGGASMELLEGKVLPGL
                     AALTEK"
     gene            8414..8941
                     /locus_tag="VQ862_001835"
     CDS             8414..8941
                     /locus_tag="VQ862_001835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000119911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HET3116133.1"
                     /translation="MSYFKKYKFDKSQFKLGMRTFKTGIAVFLVLLIFGFFGWKGLQI
                     GALTAVFSLRESFDESVHFGTSRILGNSIGGLYALVFFLLNTFFHEAFWVTLVVVPIC
                     TMLTIMTNVAMNNKAGVIGGVAAMLIITLSIPSGETISYVFVRVSETFMGVFVAIIVN
                     YDIDRIRLFLEKKEK"
     gene            9018..9374
                     /gene="glnR"
                     /locus_tag="VQ862_001836"
     CDS             9018..9374
                     /gene="glnR"
                     /locus_tag="VQ862_001836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000659547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor GlnR"
                     /protein_id="HET3116134.1"
                     /translation="MKEKEFRRNMAVFPIGSVMKLTDLSARQIRYYEDQELIKPDRNE
                     GNRRMYSLNDMDRLLEIKDYISEGYNIAAIKKKYAEREAKSKKAVSQTEVRRALHNEL
                     LQQGRFASVQSPFGRG"
     gene            9411..10757
                     /gene="glnA"
                     /locus_tag="VQ862_001837"
     CDS             9411..10757
                     /gene="glnA"
                     /locus_tag="VQ862_001837"
                     /EC_number="6.3.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glutamate--ammonia ligase"
                     /protein_id="HET3116135.1"
                     /translation="MPITAADIRREVKEKNVTFIRLMFSDILGTMKNVEIPATDEQLD
                     KVLSNKVMFDGSSIEGFVRINESDMYLYPDLDTWTVFPWGDENGSVAGLICDVYTTEG
                     EPFAGDPRGNLKRALRHMEEVGFKSFNLGPEPEFFLFKLDENGDPTLEVNDKGGYFDL
                     APTDLADNTRREIVNVLTKMGFEVEASHHEVAVGQHEIDFKYDEVLRACDKIQIFKLV
                     VKTIARKHGLYATFMAKPKFGIAGSGMHCNMSLFDAEGNNAFFDPNDPKGMQLSETAY
                     HFLGGLIKHAYNYTAIMNPTVNSYKRLVPGYEAPVYIAWAGRNRSPLVRVPASRGMGT
                     RLELRSVDPMANPYIAMAVLLEVGLYGIENKIEAPAPIEENIYIMTAEERKEAGITDL
                     PSTLHNALKALTEDEVVKAALGDHIYTSFLEAKRIEWASYATFVSQWEIDNYLDLY"
     gene            complement(10847..10966)
                     /locus_tag="VQ862_001838"
     CDS             complement(10847..10966)
                     /locus_tag="VQ862_001838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine synthetase"
                     /protein_id="HET3116136.1"
                     /translation="MPDIVFEIEFFHSDSLIFFYTSDDKSNSQKSQEDFSKNK"
BASE COUNT         3512 a         2037 c         2414 g         3044 t
ORIGIN      
        1 tagaggtgta ctattctagt ttcaatatac tatatatctg cagaatactc tttcagtttc
       61 attcagccta gtcttgctta ggaaaaagta aaaagccatc caattatgat ggatagcttc
      121 ttggttctta gatttgttct gcaaaaacct tttcagcaag gttcatagcg tggtctgata
      181 cacgagtgta gtgtgagatg atgtcgataa agttgacccc agcttgtgtt gaacattcgc
      241 ctttgttgag gcgtttgatg tgggtttttc tgagaacacg ttctatctta ttgattgctt
      301 catgacgttc tacaagactg cgtgcttttt caatatcatt gttttccaca ctatccagag
      361 catctttgat aaagtcacta gtttggcggt aaacttcctc taattctttc aaggcggcat
      421 cagaaaattc aacatttttc cgttgaagat agtcagtcag attgagtaga gcctccgtgt
      481 ggtctccaat ccgttccaaa tcacgggagg aatcaaggat attggtaagc acttcacttt
      541 ctttttggct gagagcttcg cttgaaaggg caatgagata acgtgttaat tgctcatcga
      601 tggtgttaat tgcttcttcg gttttatgcc ctttttcagc aactttttca tccaagtcaa
      661 tgatgtactt ataggaaagg tcaaaggctt tagcagcgta gtttcctaag tgcaagagct
      721 ctttcttagc atttcctaga gcgatagatg gggcctgttt gatgaaatgt tcatcaagat
      781 ataagggttc gtatttgaca acctcgtcct ctccaggaat aatcttggtt acaaagtaag
      841 ccagagctcc gataaatgga aattggacaa tggtgttggt aatattaaag gttccgtgag
      901 caaaggcgat ggtcatttcc ggtgctagat ttagcgtagc ttcaaaccaa tgaatcagga
      961 cagtaaaagg aactagaaaa ataacgcaga caactgttcc gataacgttg aaggcaacat
     1021 gagctcctgc tacccgttta gctgcaatat tagcccctaa agaggcaatg atggctgtaa
     1081 tggttgtccc gatattgtca ccaaatagaa ctggcaaagc tccctgtagg tcaattagat
     1141 tgccggcgta gaggttttgt aaaatcccaa tggtagccga agaagcttga attagcaagg
     1201 tcaagccagt accgacaaag acacccaaaa caggattctt acttagctca atcatatagt
     1261 ccttaaagac ctgtaaatcc ttgagtggag ccattgcgcc gctcatgaga ttgagggcaa
     1321 aaaagatacc accgacacca aagaggatgc gtccgatatt attgactgtc cgattttttg
     1381 taaaaaagag acagacggca ccgataaaga gcataggtag ggcatagtta cctaatttaa
     1441 aaccgatgag aaaggatgtg acagttgtcc caatattagc acccatgaca atcccgatag
     1501 cctgacgtaa ggttaagaga ccggcactga ccaggccgac tgtaataact gttacaccag
     1561 aactagactg aattagagca gtcatcccaa taccaaccag aactccaaag aaaggattac
     1621 tagtatattt gtcaatgtaa aaacgaaggc gatctccagc agcttgttgc aaaccgtctc
     1681 ccatggtctt gatactatat aagaatagcc ccagaccacc taaaaagtga aataaaattt
     1741 cctgccaatt aatggacatt tctttttcct ccgaaaaata atcgcggaat atctcctatt
     1801 ttattttaaa ggataaaagt aaatctaaca agtgttaatg tcaagtttgt aaaagaaaat
     1861 tataattgat aagtgtatta tttttaagag tttttaacct tattttagat ttgtgaaaac
     1921 agctattgtt ttttgtctaa aaatgtttta ggataaaaat gtgattatca tggttctaga
     1981 gtttgataaa aaactacaga atataaagcg ctttcttgaa aacaacaaaa tcaatctttt
     2041 aggaggagaa aatgaagaat ccattttttg aaagacgttg tcgttacagt attcgtaagt
     2101 tatcagtagg agcctgctcg ctgatgattg gtgctgtttt atttgttggt ccagccttgg
     2161 ctgaagaaac tgcagttcct gaaaatagcg gagctaatac agagcttgtt tcaggagaga
     2221 gtgagcattc gaccaatgaa gctgataagc agaatgaagg ggaacatact agagaaaaca
     2281 agctagaaaa ggcagaagga gtagcgacag catctgaaac tgcagaagca gctagcgcag
     2341 ctaaaccaga ggaaaaagca ggtgaggtgg ttgcagaaac accatctgca gaagcaaaac
     2401 ctaagtctga caaggaaaca gaagcaaagc ccgaagcaac taaccaaggg gatgagtcta
     2461 aaccagcagc agaagctaat aagactgaaa aagaagtcca gccagatgtc cctaaaaata
     2521 cagaaaaaac attaaaacca aaggaaatca aatttaattc ttgggaagaa ttgttaaaat
     2581 gggaaccagg tgctcgtgaa gatgatgcta ttaaccgcgg atctgttgtc ctcgcttcac
     2641 gtcggacagg tcatttagtc aatgaaaaag ctagcaagga agcaaaagtt caagccttat
     2701 caaacaccaa ttctaaagca aaagaccatg cttctgttgg tggagaagag ttcaaggcct
     2761 atgcttttga ctattggcaa tatctagatt caatggtctt ctgggaaggt ctcgtaccaa
     2821 ctcctgacgt tattgatgca ggtcaccgta acggggttcc tgtatacggt acactcttct
     2881 tcaactggtc taatagtatt gcagatcaag aaagatttgc tgaagctttg aagcaagacg
     2941 cagatggtag cttcccaatt gcccgtaaat tggtagacat ggccaagtat tatggctatg
     3001 atggctattt catcaaccaa gaaacaactg gagatttggt taaacctctt ggagaaaaga
     3061 tgcgccagtt tatgctctat agcaaggaat atgctgctaa ggtaaaccat ccaatcaagt
     3121 attcttggta tgatgccatg acctataact atggacgtta ccatcaagat ggtttgggag
     3181 aatacaacta ccaattcatg caaccagaag gagataaggt tccggcagat aacttctttg
     3241 ctaactttaa ctgggataag gctaaaaatg attacactat tgcaactgcc aactggattg
     3301 gtcgtaatcc ttatgatgta tttgcaggtt tggaattgca acagggtggt tcctacaaga
     3361 caaaggttaa gtggaatgac attttagacg aaaatgggaa attgcgcctt tctcttggtt
     3421 tatttgcccc agataccatt acaagtttag gaaaaactgg tgaagattat cataaaaatg
     3481 aagatatctt ctttacaggt tatcaaggag accccactgg ccaaaaacca ggtgacaaag
     3541 attggtatgg tattgctaac ctagttgcgg accgtacgcc agcggtaggt aatactttta
     3601 ctacttcttt taatacaggt catggtaaaa aatggttcgt agatggtaag gtttctaagg
     3661 attctgagtg gaattatcgt tcagtatcag gtgttcttcc aacatggcgc tggtggcaga
     3721 cttcaacagg ggaaaaactt cgtgcagaat atgattttac agatgcctat aatggcggaa
     3781 attcccttaa attctctggt gatgtagccg gtaagacaga tcaggatgtg agactttatt
     3841 ctactaagtt agaagtaact gagaagacca aacttcgtgt tgcccacaag ggaggaaaag
     3901 gttctaaagt ttatatggca ttctctacaa ctccagacta caaattcgat gatgcagatg
     3961 catggaaaga gctaaccctt tctgacaact ggacaaatga agaatttgat ctcagctcac
     4021 tagcaggtaa aaccatctat gcagtcaaac tattttttga gcatgaaggt gctgtaaaag
     4081 attatcagtt caacctcgga caattaacta tctcggacaa tcaccaagag ccacaatcgc
     4141 cgacaagctt ttctgtagtg aaacaatctc ttaaaaatgc ccaagaagcg gaagcagttg
     4201 tgcaatttaa aggcaacaag gatgcagatt tctatgaagt ttatgaaaaa gatggagaca
     4261 gctggaaatt actaactggc tcatcttcta caactattta tctaccaaaa gttagccgct
     4321 cagcaagtgc tcagggtaca actcaagaac tgaaggttgt agcagtcggt aaaaatggag
     4381 ttcgttcaga agctgcaacc acaacctttg attggggtat gactgtaaaa gataccagcc
     4441 taccaaaacc actagctgaa aatatcgttc caggtgcaac agttattgat agtactttcc
     4501 ctaagactga aggtggagaa ggtattgaag gtatgttgaa cggtaccatt actagcttgt
     4561 cagataaatg gtcttcagct cagttgagtg gtagtgtgga tattcgtttg accaagccac
     4621 gtaccgttgt tagatgggtc atggatcatg caggggctgg tggtgagtct gttaacgatg
     4681 gcttgatgaa caccaaagac tttgaccttt attataaaga tgcagatggt gagtggaagc
     4741 tagctaagga agtccgtggc aacaaagcac acgtgacaga tatcactctt gataaaccaa
     4801 tcactgctca agactggcgc ttgaatgttg tcacttctga caatggaact ccatggaagg
     4861 ctattcgtat ctataactgg aaaatgtatg aaaagcttga tactgagagt gtcaatattc
     4921 cgatggccaa ggctgcagcc cgttctctag gcaataacaa ggtacaagtt ggctttgcag
     4981 atgtacaggc tggagcaact attaccgttt atgataatcc aaattctcaa actccgctcg
     5041 caaccttgaa gagcgaagtt ggaggagacc tagcaagtgc accattggat ttgacaaatc
     5101 aatctggtct tctttattat cgtacccagt tgccaggcaa ggaaattagt aatgtcctag
     5161 cagtttccgt tccaaaagat gacagaagaa tcaagtcagt cagcctagaa acaggaccta
     5221 agaaaacaag ctacgccgaa ggggaggatt tggaccttag aggtggtgtt cttcgagttc
     5281 agtatgaagg aggaactgag gacgaactca ttcgcctaac tcacgcaggt gtatcagtat
     5341 caggttttga tacgcatcat aagggagaac agaatcttac tctccaatat ttgggacaac
     5401 cagtaaatgc taatttgtca gtgactgtca ctggccaaga cgaagcaagt ccgaaaacta
     5461 ttttgggaat tgaagtaagt cagaaaccga aaaaagatta cctagttggt gatagcttag
     5521 acttgtctga aggacgcttt gcagtggctt atagcaatga caccatggaa gaacattcct
     5581 ttactgatga gggagttgaa atttctggtt acgatgctca aaagactggt cgtcaaacct
     5641 tgacgcttcg ttaccaaggt catgaagtca actttgatgt tttggtatct ccaaaagcag
     5701 cattgaacga tgagtacctc aaacaaaaat tagcagaagt tgaagctgct aagaacaagg
     5761 tggtctataa ctttgcttca ccagaagtaa aagaagcttt cttgaaagca attgaagcgg
     5821 ccgaacaagt gttgaaagac catgaaatta gcacccaaga tcaagtcaat gaccgactta
     5881 ataaattgac agaagctcat aaagctctga atggtcaaga gaaatttaag gaagaaaaga
     5941 cagagcttga tcgtttaaca ggtgaggttc aagaactctt ggatgccaaa ccaaaccatc
     6001 cttcaggttc tgccctagct ccgcttcttg agaaaaacaa ggtcttggtt gaaaaagtag
     6061 atttgagtcc agaagagctt gcaacagcga aacagagtct aaaagatctg gttgctttat
     6121 tgaaagaaga caagccagca gtcttttctg atagtaaaac aggtgttgaa gtacacttct
     6181 caaataaaga gaagactgtc atcaagggtt tgaaagtaga gcgtgttcaa gcaagtgctg
     6241 aagagaagaa atactttgct ggagaagatg ctcatgtctt tgaaatagaa ggtttggatg
     6301 aaaaaggtca agatgttgat ctctcttacg cttctattgt gaaaatccca attgaaaaag
     6361 ataagaaagt taagaaagta tttttcttac ctgaaggcaa agaggcagta gaattggctt
     6421 ttgaacaaac ggatagtcat gttatcttta cagcaccaca ctttactcat tatgcctttg
     6481 tttatgaatc tgctgaaaaa ccacaacctg ctaaaccagc accacaaaac aaagtccttc
     6541 caaaacctac ttatcaaccg gcttctgatc aacaaaaggc tcctaaattg gaagttcaag
     6601 aggaaaaggt tgcctttcat cgtcaagagc atgaaaatgc tgagatgcta gttggggaac
     6661 aacgagtcat catacaggga cgagatggac tgttaagaca tgtctttgaa gttgatgaaa
     6721 acggtcagcg tcgtcttcgt tcaacagaag tcatccaaga agcgattcca gaaattgttg
     6781 aaattggaac aaaagtaaaa acagtaccag cagtagtagc tacacaggaa aaaccagctc
     6841 aaaatacagc agttaaatca gaagaagcaa gcaaacaatt gccaaataca ggaacagctg
     6901 atgctaatga agccctaata gcaggcttag ccagccttgg tcttgctagt ttagccttga
     6961 ccttgagacg gaaaagagaa gataaagatt aaatatcgaa aaatcttgtg aaatctttcc
     7021 ttatatttcc aaagtgtgat ataatagttt cgaataaaat aaataaagga gtttttgtaa
     7081 catggcaaaa cttactgtta aagacgttga cttgaaaggt aaaaaagtcc tcgttcgtgt
     7141 tgacttcaac gtaccattga aagatggcgt aatcactaac gataaccgta tcacagcagc
     7201 tcttccaact attaagtaca tcatcgaaca aggtggacgt gcaattcttt tctctcacct
     7261 tggacgtgtg aaagaagaag ctgataaagc tggtaaatca cttgctcctg tagcagctga
     7321 cttggcagca aaacttggtc aagatgttgt tttcccaggt gtcactcgtg gtgctgaatt
     7381 ggaagcggca atcaacgctc ttgaagatgg acaagttctc ttggttgaaa acactcgtta
     7441 cgaagatgtt gacggcaaga aagaatctaa aaacgatcct gaacttggta aatactgggc
     7501 atcacttgga gatggtatct tcgtaaacga tgcattcggt acagctcacc gtgcacacgc
     7561 atctaacgtt ggtatctcag caaacgttga aaaagcagtt gctggtttcc ttcttgaaaa
     7621 cgaaattgcc tacatccaag aagcagttga aactccagaa cgtccattcg tggctatcct
     7681 tggtggttca aaagtttcag acaagatcgg tgttatcgaa aacttgcttg aaaaagctga
     7741 taaagtcctt atcggtggtg ggatgactta cacattctac aaagcacaag gtatcgaaat
     7801 cggtaactca cttgtagaag aagacaaatt ggatgttgcg aaagctcttc ttgaaaaagc
     7861 aaatggtaaa ttgatcttgc cagttgactc aaaagaagct aacgcatttg ctggttacac
     7921 tgaagtgcgt gacactgaag gtgaagcagt ttctgaaggc ttccttggtc ttgacatcgg
     7981 tccaaaatct atcgccaaat ttgacgaagc tttgactggt gccaaaacag ttgtatggaa
     8041 cggacctatg ggtgtatttg aaaacccaga tttccaagct ggtacaatcg gtgtgatgga
     8101 cgctatcgtg aaacaaccag gagttaaatc aatcatcggt ggtggtgact cagctgccgc
     8161 agcgattaac cttggccgtg cagacaagtt ctcatggatt agtacgggtg gtggagcatc
     8221 aatggaactt cttgaaggta aggttcttcc aggacttgca gccttgacag aaaaataaga
     8281 ttttataaat aaatcaaaga agagagggat gaaagttcct cttttctttt gcttaaaata
     8341 aaaacgcttc ctctcaacta ttactcataa aaatcaccga tttatgataa aatggaaata
     8401 gaaagttgag attatgagtt attttaaaaa atataaattc gataaatccc agttcaaact
     8461 tggtatgcga acctttaaaa caggtattgc tgtttttcta gttctcttga tttttggctt
     8521 ttttggctgg aaaggtcttc aaattggtgc tttgacagcc gtttttagcc tgagggagag
     8581 ttttgatgag agtgttcatt ttgggacttc gcgtattcta ggaaatagta tcggtggact
     8641 ctatgccttg gtcttcttct tattaaatac ctttttccat gaagcctttt gggtgacctt
     8701 ggtagttgtt ccaatctgca ccatgttaac cattatgaca aatgtagcca tgaataacaa
     8761 agcaggggtt attggtggtg tagcagctat gttaatcatt accctatcaa ttccaagtgg
     8821 tgagacaatt tcgtacgtgt ttgtgcgtgt atcagaaacg tttatgggag tttttgtcgc
     8881 aattatcgta aattacgata ttgatcgtat tcgtctcttt ttagagaaaa aagaaaaata
     8941 atgttacatt ttataacatt atcaattgac gtttgtcttt ttttagacta taatagacag
     9001 aaagaaggaa attgtaaatg aaggaaaaag aatttcgccg aaatatggct gtttttccta
     9061 tcggcagtgt tatgaagttg accgatctat cggcgcgtca gattcgttat tatgaagatc
     9121 aagagttgat caagcccgat cgaaacgaag gaaatcgtcg catgtattcc ttgaatgaca
     9181 tggatcgtct gcttgaaatc aaagattata tctctgaagg ttataatatc gctgccatta
     9241 agaaaaaata tgctgaacgt gaagcgaaat ccaagaaagc ggttagtcag actgaagtac
     9301 gtcgtgcact tcacaatgaa ctcctccaac aggggcgttt tgcttcagta cagtcacctt
     9361 ttggtcgcgg ttaggcaacc gcaagtagtc atagattaag gagaaaactt atgccaatca
     9421 cagctgcaga tattcgtcgt gaagtcaagg aaaaaaatgt tacctttatt cgtcttatgt
     9481 tctcagatat tttgggaacc atgaaaaacg tcgaaattcc tgctacagat gaacagttag
     9541 ataaggtctt gtcgaacaag gttatgtttg atggatcttc tattgaaggt tttgtacgta
     9601 tcaatgagtc ggatatgtac ttgtacccgg acttggatac atggacagtc ttcccttggg
     9661 gagatgaaaa tggaagtgtt gcaggtctga tctgtgatgt ctatacaaca gaaggtgaac
     9721 catttgcggg tgaccctcgt ggtaatttga aacgagctct tcgtcacatg gaagaagttg
     9781 gattcaaatc cttcaacctt ggtccagagc cagaattctt cctatttaag ttggatgaaa
     9841 atggggaccc aacacttgaa gtgaatgaca agggtggcta ctttgatttg gcacctactg
     9901 accttgcgga caacacacgt cgtgagattg tgaatgtctt gaccaaaatg ggatttgaag
     9961 tagaagcgag tcaccacgag gttgcggttg gacagcatga gattgacttt aagtacgatg
    10021 aagttctccg tgcttgtgat aagattcaaa tctttaaact tgttgttaaa accattgctc
    10081 gcaaacacgg actttacgca acatttatgg cgaagccaaa atttggtatt gctggctcag
    10141 gtatgcactg taatatgtcc ttgtttgatg cagaaggaaa taacgccttc tttgatccaa
    10201 atgatccaaa aggaatgcag ttgtcagaaa cagcttacca tttcctaggc ggtttgatca
    10261 agcatgctta caactatact gccatcatga acccaacagt taactcatac aaacgtttgg
    10321 ttccaggtta tgaagcgcct gtttacattg cttgggctgg tcgtaaccgt tcgccacttg
    10381 tgcgcgtacc tgcttcacgt ggtatgggaa ctcgtcttga gttgcgttca gtggatccaa
    10441 tggcgaaccc ttacattgct atggctgttc ttttggaagt tggtttgtat ggtattgaaa
    10501 ataaaatcga agcaccagct cctatcgaag aaaatatcta catcatgaca gcagaagagc
    10561 gcaaggaagc tggtattaca gaccttccat caactcttca taatgctttg aaagctttga
    10621 cagaagatga agtggttaaa gctgctctcg gagatcacat ctacactagc ttccttgaag
    10681 ccaaacgaat cgaatgggca agttatgcaa ccttcgtttc acaatgggaa attgataatt
    10741 atttagacct ttactaatat agaagaaaga ttgcctgtgg gtaaacagtc acacagcagt
    10801 ctaagccatc aaatacctat aacccttaaa atagcgattt cggtcgctat ttatttttcg
    10861 aaaaatcctc ttgactcttt tgcgaattag atttatcatc agacgtgtag aagaaaatca
    10921 aggagtcact atggaaaaat tcaatttcaa aaacaatatc gggcaagaaa acaagttact
    10981 tcaaatcgaa atctacaagt ttactaa
//
LOCUS       DAVBOD010000066        10756 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 640-05
            SAMEA1012484-rid20186543.denovo.066, whole genome shotgun sequence.
ACCESSION   DAVBOD010000066 DAVBOD010000000
VERSION     DAVBOD010000066.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012484
            Sequence Read Archive: ERR059358
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10756)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10756)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979948.1
            Genome Coverage       :: 595x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:03:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,266
            CDSs (total)                      :: 2,219
            Genes (coding)                    :: 2,091
            CDSs (with protein)               :: 2,091
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 71 of 128
            Pseudo Genes (incomplete)         :: 50 of 128
            Pseudo Genes (internal stop)      :: 33 of 128
            Pseudo Genes (multiple problems)  :: 22 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10756
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012484-rid20186543.denovo.066"
                     /strain="NIG 640-05"
                     /db_xref="taxon:1313"
     gene            <1..270
                     /locus_tag="VQ862_001839"
     CDS             <1..270
                     /locus_tag="VQ862_001839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET3116137.1"
                     /translation="QHDSYHRFLESKGIQASMSRKGNSQDNGRMESFFGILKSEMFYG
                     YEKTFKSLNQLEQAIIDYIDYYNNKRIKVKLKGLSPVQYRTKSFG"
     gene            complement(386..1189)
                     /locus_tag="VQ862_001840"
     CDS             complement(386..1189)
                     /locus_tag="VQ862_001840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fic/DOC family protein"
                     /protein_id="HET3116138.1"
                     /translation="MQSTYNIDNPNLSYEAKRDLWRIGFGLQKVDNLVPSAYMESLAE
                     KQSRGELTYEQVYEDATAYHHTIDASTEEADLVSLRIVELLSRRGFSFSPATLLAIHK
                     ELFQDIFEPSIPVGQFRQTNITKNEPVLNGESVVYSDYSMIQMTLDYDFNQEKQVAYA
                     TLTQADVVKQIQHFISGIWQIHPFREGNTRTVTVFLIQYLREFGFDIDNIPFQQHSKY
                     FRDALVLDNAKILQRRPEFLTAFFENLLLGGQNDLSSEKMYLDLDLDFS"
     gene            complement(1464..2219)
                     /locus_tag="VQ862_001841"
     CDS             complement(1464..2219)
                     /locus_tag="VQ862_001841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000033780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3883 domain-containing protein"
                     /protein_id="HET3116139.1"
                     /translation="MSKHPHYELLNLIGYGLAKFAKLFIKEFQYSSKSEFYRYVVSLG
                     IAETTGVVKNRMDLFDPYFDNSRKGWWQKAEVYRFRKDLIDMMFGNEDVHSYVEIVKM
                     LLASEGKQTGITIIEKPIIRTKFKRLQETGMEAENYFILHFDKEEKFQGGQLTDACLY
                     GDGYDFQVDIQEHSYLAEVKGIRKPKGRVRLTAYEFEKAKEFQSDFILSLVTNLDDIP
                     KLVLVDNPLKHFEFKKNIIKNEIIEYRSVEDLY"
     gene            complement(2289..4940)
                     /locus_tag="VQ862_001842"
     CDS             complement(2289..4940)
                     /locus_tag="VQ862_001842"
                     /EC_number="6.1.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009732359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="valine--tRNA ligase"
                     /protein_id="HET3116140.1"
                     /translation="MSKELSSKYNPAEVEAGRYQKWLDADVFKPSGDQKAKPYSIVIP
                     PPNVTGKLHLGHAWDTTLQDIIIRQKRMQGFDTLWLPGMDHAGIATQAKVEERLRGEG
                     ISRYDLGRESFLTKVWEWKDEYATTIKEQWGKMGLSVDYSRERFTLDEGLSKAVRKVF
                     VDLYKKGWIYRGEFIINWDPAARTALSDIEVIHKDVEGAFYHMNYMLEDGSRALEVAT
                     TRPETMFGDVAVAVNPEDPRYKDLIGKNVILPIANKLIPIVGDEHADPEFGTGVVKIT
                     PAHDPNDFLVGQRHNLPQVNVMNDDGTMNELAFEFSGMDRFEARKAVVAKLEEIGALV
                     KIEKRVHSVGHSERTGVVVEPRLSTQWFVKMDQLAKNAIANQDTEDKVEFYPPRFNDT
                     FLQWMENVHDWVISRQLWWGHQIPAWYNADGEMYVGEEAPEGDGWTQDEDVLDTWFSS
                     ALWPFSTMGWPEVDSEDFKRYFPTSTLVTGYDIIFFWVSRMIFQSLEFTGRQPFQNVL
                     IHGLIRDEEGRKMSKSLGNGIDPMDVIDKYGTDSLRWFLSNGSAPGQDVRFSYEKMDA
                     SWNFINKIWNISRYILMNNEGLTLDVAHDNVTKVATGEAGNVTDRWILHNLNETIAKV
                     TENFDKFEFGVAGHILYNFIWEEFANWYVELTKEVLYSDNEDDKVITRSVLLYTLDKI
                     LRLLHPIMPFVTEEIFGQISEGSIVTAAYPTVNLAFEDLAAHTGVESLKDLIRAVRNA
                     RAEVNVAPSKPITILVKTSDSDLEAFFNSNVNYIKRFTNPEHLEIASTIPAPELAMSS
                     VITGAEIYLPLADLLNVEEELARLDKELAKWQKELDMVGKKLSNERFVANAKPEVVQK
                     ERDKQADYQAKYDATVARIDEMKKLVK"
     gene            complement(4933..5511)
                     /locus_tag="VQ862_001843"
     CDS             complement(4933..5511)
                     /locus_tag="VQ862_001843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000550018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HET3116141.1"
                     /translation="MHLFIIGAPASGKMTIGQELSRLTDATLFYNHQAIDFALEIYQD
                     YTEEMWEFVRGITFSFLGASARNQRSVILTDVIDFSNQYHLIYLKQIQNLLDDYHQEI
                     LFVELETSLEECIRRNRTENRLKHKPLKRHIEVSEREILETAETLQLNSQYQPNELHH
                     YFKINNTNLSAEEAAKQIQNKINKIEKGHTHV"
     gene            complement(5511..6071)
                     /locus_tag="VQ862_001844"
     CDS             complement(5511..6071)
                     /locus_tag="VQ862_001844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000124561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET3116142.1"
                     /translation="MARTELPDKIETERLVLRVRTVADAEDIFDYASLPEVAYPAGFP
                     PVKTLEDEIYYLEHILPERNQKENLPAGYGIVVKGTDKIVGSIYFNHRHEDDVMEIGY
                     TLHSDYWGRGYVPEAARALIDLAFKDLGLHKIELTCFGYNLQSQRVAEKLGFTLEARI
                     RDRKDAQGNCCDDLRYALLKSEWGVI"
     gene            complement(6058..6507)
                     /locus_tag="VQ862_001845"
     CDS             complement(6058..6507)
                     /locus_tag="VQ862_001845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavin reductase"
                     /protein_id="HET3116143.1"
                     /translation="MIGVVARENAAEQIKQYQKFTVNISDETSMLAMEQAGFISHQEK
                     LERLGVHYEISERTQTPILDACPLVLDCRVDRIVEEDGICHIFAKILERLVAPELLDE
                     KGHFKNQLFAPTYFMGDGYQRVYRYLDKRVDMKGSFIKKARKKDGKN"
     gene            complement(6920..7315)
                     /locus_tag="VQ862_001846"
     CDS             complement(6920..7315)
                     /locus_tag="VQ862_001846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase"
                     /protein_id="HET3116144.1"
                     /translation="MSKKLNRKKQLRNGLRRAGAFSSTVTKVVDETKKVVKRAEQTAS
                     AAGKAVSKKVEQAVEATKEQAQKVANSVEDFAANLGGLPLDRAKTFYDEGIKSASHFK
                     NWTEKELLDLKGIGPATIKKLKENGIKFK"
     gene            complement(7411..7665)
                     /locus_tag="VQ862_001847"
     CDS             complement(7411..7665)
                     /locus_tag="VQ862_001847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000119704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1912 family protein"
                     /protein_id="HET3116145.1"
                     /translation="MSYEQEFMKEFEAWVNTQIMINDMAHKESQKVYEEDQDERAKDA
                     MIRYESRLDAYQFLLGKFENFKVGKGFHDLPEGLFGERNY"
     gene            complement(7675..9009)
                     /locus_tag="VQ862_001848"
     CDS             complement(7675..9009)
                     /locus_tag="VQ862_001848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000752887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF438 domain-containing protein"
                     /protein_id="HET3116146.1"
                     /translation="MADERIHVLRDILLELHNGASPESVQERFDATFAGVSAIEISLM
                     EHELMNSDSGVTFEDVMELCDVHANLFKNAIKGVEVSDTEHPGHPVRVFKEENLALRA
                     ALIRIRRLLDTYESMEDEEMLAEMRKGLVRQMGLVGQFDIHYQRKEELFFPIMERYGH
                     DSPPKVMWGVDDQIRELFQTALTTAKSLPEVSISSVKEAFEAFATEFESMIFKEESIL
                     LMILLESFTQDDWLQIAEESDAYGYAIIRPSEKWVPERQIFIEEKIAEEPVQLDTAEG
                     QVQQVIDTPEGHFTITFTPKEKEAVLDRHSQQAFGNGYLSVEQANLILNHLPMEITFV
                     NKEDIFQYYNDNTPADEMIFKRTPSQVGRNVELCHPPKYLDKVKAIMKGLREGTKDKY
                     EMWFKSESRGKFVHITYAAVHDEDGEFQGVLEYVQDIQPYREIDTDYFRGLE"
     gene            complement(9009..9242)
                     /locus_tag="VQ862_001849"
     CDS             complement(9009..9242)
                     /locus_tag="VQ862_001849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006144975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1858 domain-containing protein"
                     /protein_id="HET3116147.1"
                     /translation="MDNIIDVSIPVAEVVDKHPEVLEILVELGFKPLANPLMRNTVGR
                     KVSLKQGSKLAGTPMDKIVRTLEANGYEVIGLD"
     gene            complement(9555..9695)
                     /locus_tag="VQ862_001850"
     CDS             complement(9555..9695)
                     /locus_tag="VQ862_001850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000668195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3116148.1"
                     /translation="MKFFWGLLAIIFIKPIIGIVKFFWMIISFAVQLLFYKILDWFFK
                     LI"
     gene            complement(9692..9874)
                     /locus_tag="VQ862_001851"
     CDS             complement(9692..9874)
                     /locus_tag="VQ862_001851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001068155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3116149.1"
                     /translation="MNPIKAFAKIYGNYFLTVQGVKVMKTIKKDDNAVVGLGKLFIAD
                     KLMDTARWLIKPEDKK"
     gene            complement(9876..10655)
                     /locus_tag="VQ862_001852"
     CDS             complement(9876..10655)
                     /locus_tag="VQ862_001852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3116150.1"
                     /translation="MAEQDLAMQVLQQVVKLPVVKVDRSKFLVDKFSKELGPQDIPTL
                     LEQGPTSLLSQEILDRVANACIRDNVLLASGTSVLAGLPGGLAMAITIPADVAQFYGF
                     SLKLAQELGYIYGYEDLWASRDELSEDAQNTLLLYLGVMLGVNGTAALLRAGGITIAK
                     QVMKTVPNKALTKTLWYPILKKVLRIFGVNLTKGGLAKGMGKFIPILGGIISGGLTFA
                     TMKPMGESLQKELSKLVNYSEVQYQEDVETIRKEAEIIKGE"
BASE COUNT         3148 a         2392 c         1993 g         3223 t
ORIGIN      
        1 caacacgatt cttatcatcg gttcctagag agtaagggaa ttcaagcatc catgtcacgt
       61 aagggcaaca gccaagacaa cggtaggatg gaatctttct ttggcatttt aaaatccgaa
      121 atgttttatg gctatgagaa aacatttaaa tcacttaatc aattggaaca agccattata
      181 gactatattg attattacaa caacaaacga attaaggtaa aactaaaagg acttagccct
      241 gtgcaataca gaactaaatc cttcggataa attaattgtc taactgtttg gggtcagtac
      301 attttaacac ttgatactat gcgttttatt gtgggaatgt ttacttcatt ttttcctaaa
      361 attcaatgtt tactcagtat ttggattatg aaaaatcgag gtctaaatct agatacattt
      421 tttctgaaga caaatcattt tgaccaccga gcaagagatt ttcaaaaaaa gctgttaaaa
      481 actcaggacg tcgctgtaaa atctttgcat tatctaatac caaggcatca cgaaaatact
      541 tggaatgttg ctgaaatggt atattatcaa tatcaaaacc aaactcacga agatactgaa
      601 tcaaaaagac cgttactgtc cgagtgtttc cttcgcgaaa tggatgaatc tgccagattc
      661 ctgaaataaa atgctggatt tgtttaacca catccgcctg agttagtgtc gcatatgcaa
      721 cttgtttttc ctgattaaaa tcataatcta aggtcatttg aatcatggag taatcagagt
      781 acacaacact ttcaccattc aaaacaggtt cattctttgt gatattggtc tgacgaaatt
      841 gccccaccgg aatagagggt tcaaatatat cttgaaacaa ctccttatga atagcaagta
      901 aggtcgcagg actaaagcta aagcctcttc gagacaatag ttctacaata cgtagagaaa
      961 ccaagtctgc ctcttccgta cttgcatcaa tagtatggtg ataagccgtt gcatcctcat
     1021 aaacctgctc ataagtcagt tctccccggg actgtttctc agccaaagat tccatatacg
     1081 ctgatggcac tagattgtca actttctgca gaccaaaacc tatccgccat aaatcacgct
     1141 tcgcttcata agacaagttt ggattgtcaa tgttgtaagt tgattgcata gaaatatcct
     1201 ttcaattgtt tttcttcatt accagtaaat cacgaaattg gttggaaact ggcttaaact
     1261 ataaaaagtc ctcacaatag gttctatgat atatatatac ttcatgtaaa taataaaaga
     1321 gttataatca gcactactga taaattcaat accgatttcg ccatcttaaa acttagtcaa
     1381 acgaataccg ttgatttcca gttcattaag tcgttgacct gtcaagactt ctcgttcctt
     1441 caactggaaa agttaagggg gaactaatac aaatcctcta cgcttctata ttcaatgatt
     1501 tcatttttta taatattctt tttaaactca aaatgtttta gaggattatc aactaatact
     1561 aactttggaa tatcatctag gttggtgacc agagataaaa taaaatctga ttgaaactct
     1621 ttagctttct caaattcgta ggcagttaaa cggacacgac ccttaggttt tcgaatccct
     1681 ttaacttcgg caaggtagga atgttcttga atatctactt ggaaatcata tccatcacca
     1741 taaagacatg catcggttaa ctgtccacct tgaaattttt cttctttatc aaaatgaagg
     1801 ataaaataat tctctgcctc catccccgtt tcctgtagac gtttgaattt agttcgaata
     1861 attggttttt caattatagt aatgcctgtt tgctttcctt cactagcaag taacatttta
     1921 acaatttcaa cataactatg aacatcttca tttccaaaca tcatatcaat taaatcttta
     1981 cgaaaacggt aaacttcagc tttctgccac caaccttttc gactattgtc aaaataagga
     2041 tcaaataaat ccattctatt ttttacaact ccagttgttt cagcaattcc caaagaaacc
     2101 acatagcgat aaaactccga cttactagaa tattgaaatt cttttataaa aagcttggca
     2161 aacttggcaa gaccgtagcc aattaaattt aacaattcat aatgcgggtg tttagacatc
     2221 actttctcca tcaatagata gtaatttcat tatcccaaaa aacacggcat tacaccatgt
     2281 ttctgtgttt atttcaccaa cttcttcatc tcatcaatac gtgctacggt cgcatcatac
     2341 ttggcttggt agtcagcttg tttgtcgcgt tctttttgga cgacttctgg tttggcgttg
     2401 gctacgaagc gttcgttaga gagcttctta ccgaccatgt ccagttcttt ttgccattta
     2461 gcaagttcct tgtcaagacg agccagttct tcttcgacat tgaggaggtc agccaatggc
     2521 aggtagattt ctgctcctgt aatgacgctt gacatagcca gttcaggtgc agggatggtt
     2581 gatgcgattt ccaagtgttc tggatttgta aagcgtttga tatagttgac attgctgtta
     2641 aagaaggctt ccaagtcgct atcgcttgtc ttaacaagga tggtgatagg cttgcttggt
     2701 gctacgttta cttccgcacg cgcattacga acggcacgga tcaagtcttt gagactttct
     2761 acaccagtat gagccgcaag gtcttcaaag gctagattaa cagttgggta tgcagctgtc
     2821 acgatagaac cttctgagat ttgtccaaag atttcctctg tcacgaatgg catgattggg
     2881 tgaaggagac gaaggatctt gtccagagtg taaaggagaa cagatcgagt aatgacctta
     2941 tcgtcttcat tgtcgctgta aaggacttcc ttggtcaatt caacatacca gttggcaaat
     3001 tcttcccaaa tgaagttgta aaggatatga ccagccacac caaactcgaa cttatcaaag
     3061 ttttcagtaa cttttgcaat ggtttcgttg agattgtgga gaatccagcg gtccgtcaca
     3121 ttaccagcct cacctgttgc aacttttgtg acattgtcat gcgccacatc cagcgtcaaa
     3181 ccttcattgt tcatgaggat atagcgagaa atgttccaaa ttttgttaat aaagttccat
     3241 gaagcatcca ttttctcgta agagaaacga acgtcttgac caggagctga gccgtttgac
     3301 aagaaccaac gaagactatc tgtaccatat ttatcaataa catccattgg gtcaatgcca
     3361 tttccaagag atttagacat cttacgtcct tcttcatcac gaattagacc atggataagg
     3421 acgttttgga atggttgacg gcctgtgaat tccaatgact ggaagatcat acgagacacc
     3481 cagaagaaga tgatgtcgta acctgttacc aaggttgaag ttgggaaata acgtttaaag
     3541 tcttctgagt caacttcagg ccagcccatg gttgaaaatg gccagagggc agaactgaac
     3601 caagtatcca agacgtcttc gtcctgagtc catccgtcac cttctggagc ttcttcgccg
     3661 acatacattt caccatcagc attgtaccag gcagggattt ggtgacccca ccaaagctga
     3721 cgagagataa cccagtcgtg gacattttcc atccattgaa ggaaggtatc gttgaaacga
     3781 ggtgggtaga attcgacctt gtcctctgtg tcttggttgg caatggcgtt cttagccaat
     3841 tggtccatct tgacgaacca ttgagtagac aagcgtggct caactacgac acctgtccgt
     3901 tctgagtgac cgactgaatg gacacgtttt tcgattttga caagggcacc gatttcttcc
     3961 aacttagcaa cgactgcctt acgagcttca aaacgatcca tgcctgaaaa ttcaaaggca
     4021 agctcattca tagttccgtc gtcgttcatg acgttgactt gtggcaagtt atgacgttgg
     4081 ccaaccaaga agtcatttgg atcgtgggca ggtgtgattt tcacgacacc agtaccaaac
     4141 tcaggatctg cgtgctcatc tccaacgatt gggatgagtt tattagcgat tggaaggatg
     4201 acgtttttac caatcaagtc cttgtagcgc gggtcttctg gattaaccgc aaccgcaacg
     4261 tccccaaaca tagtctcagg acgagttgta gcaacttcaa gggcgcgtga accatcttcc
     4321 agcatgtagt tcatgtggta gaaggcacct tcgacatcct tgtgaatcac ctcaatatca
     4381 gaaagggctg tgcgagctgc tgggtcccag ttgatgataa actcaccacg gtagatccag
     4441 cctttcttgt aaaggtccac aaagacctta cgaacagctt ttgacaaacc ttcgtcaaga
     4501 gtgaaacgct cacgagagta gtctacagag agccccatct tgccccattg ttccttgata
     4561 gtagtggcat attcgtcttt ccattcccag actttcgtca agaaagactc acgaccaagg
     4621 tcatagcggg aaatgccctc accacgcaag cgctcctcta ccttagcctg agtggcaatc
     4681 cctgcgtggt ccatcccagg aagccaaagg gtatcaaaac cttgcatgcg tttttgacgg
     4741 atgataatat cttgcaaagt tgtatcccaa gcgtgaccaa ggtgaagttt acctgtaacg
     4801 tttggtggtg gaataacgat tgaataaggc ttagcctttt gatcgcctga aggcttgaaa
     4861 acatcagcat caagccattt ttggtaacga ccagcctcaa cctcggctgg attgtattta
     4921 gatgaaagtt ctttagacat gtgtgtgtcc tttctctatt ttgtttattt tattttgaat
     4981 ttgcttagca gcttcttctg cagacaaatt cgtattattt attttaaagt agtggtgcaa
     5041 ctcattcggt tgatattggg aatttaattg aagtgtttca gcggtctcta aaatttctct
     5101 ttcagatacc tcaatatgtc gttttaaggg tttgtgcttt aatcgattct ccgttcgatt
     5161 tcgacgtatg cactcttcaa gacttgtttc caactcaaca aaaagaatct cttgatgata
     5221 atcatccaac aaattctgaa tttgctttaa atatatcaga tgatactgat ttgaaaaatc
     5281 aattacatct gttaaaatta ctgatcgctg atttcttgca cttgctccaa ggaatgaaaa
     5341 agtgattcca cgaacaaatt cccacatttc ctctgtatag tcctgataga tttctagtgc
     5401 aaaatcaatg gcttgatggt tataaaatag ggtagcatcc gtcagtcgag ataattcttg
     5461 accaatggtc atttttcctg atgctggagc accaatgatg aaaagatgca tcaaatcacc
     5521 ccccactcac tcttcagcaa ggcatatctc aaatcatcac agcagttgcc ttgagcatct
     5581 ttacggtctc ttatgcgagc ttcgagggta aagccaagct tttccgcgac tcgttgactt
     5641 tgaaggttat atccaaagca agttagttca atcttgtgaa gacccaaatc tttaaaggct
     5701 aagtcaatca aggcacgcgc agcttctggc acataacctc gcccccaata gtctgagtgt
     5761 aaggtatagc cgatttccat cacatcatct tcatggcgat ggttgaaata gatagagcca
     5821 acgatcttat ccgttccttt gacgacaatc ccgtagcctg ctgggagatt ttccttttga
     5881 ttacgctccg gaagaatgtg ctccagataa taaatctcat cttccaaggt cttgactgga
     5941 ggaaaacctg ctggataggc gacctctggc aaactagcat agtcaaagat atcctcagca
     6001 tccgccacag tacggactcg taaaacgaga cgttctgttt cgattttatc tggcagctca
     6061 gttcttgcca tccttcttcc tcgctttttt gatgaaactg cccttcatat ctacacgctt
     6121 gtccagatag cgataaacgc gctgatatcc atctcccatg aaataggttg gggcaaacag
     6181 ttgattttta aaatgtccct tttcatccag gagttctggg gcaacaagtc gctcaagaat
     6241 cttggcaaag atgtggcaaa taccgtcttc ctcaacaatc ctatctaccc gacaatctaa
     6301 aacaagtgga caggcgtcta aaataggagt ctgagttcgt tcagaaattt cataatgcac
     6361 tcccaaacgt tccaatttct cctgatgact gataaaacca gcctgctcca tcgcaagcat
     6421 agaagtttca tcagaaatat tcacagtaaa tttttgatac tgtttgatct gctctgcggc
     6481 attctctctc gcaacgactc caatcacaac ccaatctcct agactataag aggaactaca
     6541 ggtcgtgatg ttatagccaa aattctaatc ttgatatcct aaaataaaaa caggaaaacc
     6601 ataatatagt ttacttgtgt taaaagattg cttcataaca accccctttg actaagacgt
     6661 aaaagaaaag ccctgccatc tacatgacag ggacgaatgt gtttatccgc ggtaccaccc
     6721 aatttcgggc agttgcccgc aactctcgtc tttaaagcaa aaagacactt ttatttcaat
     6781 ttttcatcca ttagcaacca gttttgacac atttgtggac ttctcagcgc cgccactttc
     6841 tgtaaaatgt gggattcaaa acacctctaa tggctctatt gtagcaagat tttttcggaa
     6901 atgcaaggct caagaaaaat tacttgaact tgatgccatt ttctttcaat ttcttgatgg
     6961 tagctgggcc gattcctttc aagtcaagga gttctttttc agtccagttt ttgaaatgtg
     7021 aagcagactt gattccttca tcatagaaag tcttggcacg atcaagtgga agtccaccca
     7081 aatttgctgc aaaatcttct acagaattag ctactttttg agcttgctct ttggtagctt
     7141 ctactgcttg ttcaactttt ttagaaacag ccttaccagc tgcgcttgct gtctgttctg
     7201 cacgcttcac gacttttttt gtctcatcta caaccttagt cacagtactt gaaaaggcac
     7261 ctgcgcgacg gaggccattt cgtaattgtt ttttacgatt gagtttcttt gacatgataa
     7321 aatcctttca ataaaaaatc cctgctctga caaggattta acataaacat tctatcaaga
     7381 ttttagtgaa aaatcaagaa tctttctcgt ttaataattt cgctcaccaa acaagccttc
     7441 tggcaaatca tggaatccct tgcctacttt gaagttttca aacttaccaa gcaagaactg
     7501 ataagcatcc aagcgactct cgtagcgaat catggcatct ttggcacgct cgtcctggtc
     7561 ttcttcgtaa actttttgac tttccttgtg cgccatatcg ttaatcatga tttgggtatt
     7621 gacccaagct tcaaattcct tcataaattc ttgttcgtaa ctcatttttt ctccttattc
     7681 taatccacga aaatagtccg tatcaatctc acggtagggc tggatatcct gaacatactc
     7741 caacactcct tggaattctc cgtcttcatc gtgtactgca gcataggtga tgtggacaaa
     7801 cttacctcgc gactcagact tgaaccacat ttcatacttg tccttggtcc cctcacgaag
     7861 tcccttcatg atagccttga ccttgtccaa atacttaggc ggatgacaga gttcgacatt
     7921 gcgcccgact tgggacggcg tccgtttgaa aatcatctca tcagctggcg tattgtcatt
     7981 gtaatactgg aaaatatctt ctttattgac aaaggtaatc tccataggga gatgattgag
     8041 gatgagattg gcctgctcga ctgaaagata gccattacca aaagcctgtt gactatggcg
     8101 gtccagcaca gcttcctttt ccttaggggt aaaggtaatg gtaaaatggc cttctggcgt
     8161 atctatgact tgttgaactt gaccttctgc cgtatctagt tgtacaggct cctctgcaat
     8221 cttttcctca ataaagatct gtcgttctgg cacccatttc tctgacggac ggatgatggc
     8281 atagccatag gcatcactct cctccgcaat ctgaagccag tcatcctgag taaaagactc
     8341 aaggagaatc atgagcagga tggactcttc cttgaaaatc atactttcaa actctgtcgc
     8401 aaaagcttca aaagcttcct ttacactgct aattgacact tctggtagtg acttggctgt
     8461 cgttagagct gtttgaaaga gttccctaat ctgatcatcc actccccaca taactttggg
     8521 aggtgaatcg tgtccatagc gctccatgat aggaaagaag agttcttcct tacgttggta
     8581 atggatgtca aattgaccca caagtcccat ctgacgcacc aaacccttac gcatctccgc
     8641 cagcatttcc tcgtcttcca tagactcata ggtatctaac aatctacgaa tgcgaatcaa
     8701 ggccgcacgg agagccagat tttcttcttt gaagacacga actgggtgac ctggatgctc
     8761 agtatctgaa acttcgacac ctttgatagc atttttaaaa agattggcat ggacatcaca
     8821 gagttccata acatcttcaa aagtgacgcc cgaatccgag ttcatcagct cgtgctccat
     8881 aagggaaatc tcaatggctg agacacccgc aaaggtcgca tcaaaacgct cctgaaccga
     8941 ctcaggagag gcgccattat gcaattctaa taaaatatcc cgtaggacat gaatccgttc
     9001 atctgccatt agtctaatcc aatcacttcg tagccattcg cttccagtgt gcgtacaatc
     9061 ttgtccatag gagttcctgc tagcttagaa ccctgtttaa gtgatacttt acgaccaact
     9121 gtattgcgca ttaagggatt ggcaaggggt ttaaaaccca actccactag aatttccaag
     9181 acttctggat gcttgtccac cacttctgca acaggaattg acacatcgat gatattgtcc
     9241 atgacgacct ccattatatg ttctaatact caatgaaaat caaagagcaa actaggaagc
     9301 tagccgcagg ttgctcaaaa cagtgctttg agattgtaga tagaactgac gaagtcagct
     9361 caaaacaccg ttttgaggtt gcggatagaa ctgacgaagt cagtaacata tatacagcaa
     9421 ggtgaagctg acgtggtttg aagagatttt cgaagagtat aaaatgattt tactgcttat
     9481 attataccat atggaaagag aataaaaaac tagcagtgga gttcctgcta gttctctgcg
     9541 acttggatta ccatctagat aagtttaaag aaccaatcca atatcttgta aaacagcaat
     9601 tggactgcaa aagagatgat catccaaaag aatttcacaa tcccaataat cggtttgata
     9661 aaaataatgg caagaagtcc ccagaaaaat ttcatttttt atcctctggc ttaatgagcc
     9721 accgagccgt atccattaac ttgtcggcaa taaaaagttt ccccagaccg acaacggcat
     9781 tatcatcttt ctttatcgtt ttcattactt ttacaccttg cacggtcaaa aagtaattac
     9841 cataaatttt agcaaaagct ttgataggat tcatattact ctcctttgat gatttcagcc
     9901 tcttttcgga ttgtttcaac atcttcttga tattgaactt cactatagtt gactagcttg
     9961 gataattctt tctgcaagct ttcccccatt ggtttcatag ttgcaaaggt taaaccacct
    10021 gaaatgatac cacccaagat aggaataaat ttccccattc ctttggccag ccctcccttg
    10081 gtaagattca caccaaatat tcttaagact ttcttcaaaa taggatacca aagcgtcttt
    10141 gttaaagctt tattaggtac tgttttcatt acctgtttgg caattgttat accaccagca
    10201 cgtagcaaag cagcagttcc attcaccccc aacatgacgc ctagataaag caaaagggta
    10261 ttttgagcat cttcactcaa ctcatcgcgt gaagcccaaa gatcctcata accataaata
    10321 taacctaatt cttgggccaa tttcagagag aaaccataaa attgagccac atcagctgga
    10381 atggtaattg ccatagcaag ccctccaggt aatcctgcca aaacagaagt cccactcgct
    10441 aataaaacat tatccctaat acaggcatta gccactcgat ctaagatttc ttgagataag
    10501 agagacgttg gaccttgttc caataaggta ggaatgtcct gtggacccaa ttctttggaa
    10561 aacttatcca ctaaaaattt cgaacgatca accttaacaa caggtagttt caccacttgt
    10621 tgcaatactt gcatagctaa gtcttgttca gccatataca aactccttat ttcttttttg
    10681 caccttatca tattatattt cctacaaaaa aagcattttc taattagata acattaaaaa
    10741 atacagaacc cctttt
//
LOCUS       DAVBOD010000067        10754 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 640-05
            SAMEA1012484-rid20186543.denovo.067, whole genome shotgun sequence.
ACCESSION   DAVBOD010000067 DAVBOD010000000
VERSION     DAVBOD010000067.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012484
            Sequence Read Archive: ERR059358
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10754)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10754)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979948.1
            Genome Coverage       :: 595x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:03:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,266
            CDSs (total)                      :: 2,219
            Genes (coding)                    :: 2,091
            CDSs (with protein)               :: 2,091
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 71 of 128
            Pseudo Genes (incomplete)         :: 50 of 128
            Pseudo Genes (internal stop)      :: 33 of 128
            Pseudo Genes (multiple problems)  :: 22 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10754
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012484-rid20186543.denovo.067"
                     /strain="NIG 640-05"
                     /db_xref="taxon:1313"
     gene            complement(117..1541)
                     /locus_tag="VQ862_001853"
     CDS             complement(117..1541)
                     /locus_tag="VQ862_001853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent glyceraldehyde-3-phosphate
                     dehydrogenase"
                     /protein_id="HET3116151.1"
                     /translation="MTRYQNLVNGKWKSSEQEITIYSPINQEELGTVPAMTQTEADEA
                     MQAARAALPAWRALSAIERAAYLHKTAAILERDKEEIGTILAKEVAKGIKAAIGEVVR
                     TADLIRYAAEEGLRITGQAMEGGGFEAASKNKLAVVRREPVGIVLAIAPFNYPVNLSA
                     SKIAPALIAGNVVMFKPPTQGSISGLLLAKAFEEAGIPAGVFNTITGRGSEIGDYIIE
                     HKEVNFINFTGSTPIGERIGRLAGMRPIMLELGGKDAALVLEDADLEHAAKQIVAGAF
                     SYSGQRCTAIKRVIVLESVADKLATLLQEEVSKLTVGDPFDNADITPVIDNASADFIW
                     GLIEDAQEKEAQALTPIKREGNLLWPVLFDQVTKDMKVAWEEPFGPVLPIIRVASVEE
                     AIAFANESEFGLQSSVFTNDFKKAFEIAEKLEVGTVHINNKTQRGPDNFPFLGVKGSG
                     AGVQGIKYSIEAMTNVKSIVFDVK"
     gene            complement(2085..4364)
                     /gene="pulA"
                     /locus_tag="VQ862_001854"
     CDS             complement(2085..4364)
                     /gene="pulA"
                     /locus_tag="VQ862_001854"
                     /EC_number="3.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000283081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I pullulanase"
                     /protein_id="HET3116152.1"
                     /translation="MYNYPMRIHYHRKNGEYDTCSFVKSQDQRIDLLTYKEDYFGALF
                     SFEHPSSHVIESLNFVVHTGQTSKEYSIRFNHYPLLTEVWILEGDDRIYYSENPAIAS
                     PFYKNQNPFAFDKAINSASFDHHWGYQGELGCRVEDNQAHFSLWSPTATEVQVVVYES
                     AANDAPVWKTFEMKRGNSYSYNHKDNTIGVWSLDVEEDLVGKAYQYQVQFPHHQTLTR
                     DPYTIATSPDGKRSAILSHVEKQVENFEVKHGSEATWRLENPCKAVICEMHIRDLTKS
                     PTSGVDEHLRGTFLGAAQAGTVNQYGQSTAFDYIKKLGYNYVQLQPIADRHKEYDEDG
                     NVTYNWGYDPQNYNAPETSFSTNPDDPAQVIRDLKVMVQAYHDAGIGVIMDVVYNHTF
                     SVVDAPFQTTVPDYYYRMNPDGTFQNGTGVGNETASEHEMFRKYMIDSLLYWVQEYNI
                     DGFRFDLMGIHDVKTMQMIRQSLDEIDSNIILYGEGWDMGTGLAPYDKAKKDNAYQMP
                     NIGFFNDNQRDAVKGGEVYGAIKSGFVSGAATEPILAKAILGSRELGSYTHPNQVLNY
                     VEAHDNYNLHDLLATLHPDQSSEQIMRKVETATAMNLLMQGMAFMEIGQEFGRTKLVA
                     TGENGELTHDDRERAMNSYNAPDSVNQVNWNLINERQDSIEFIRQVIRLKTKTGAFSY
                     SSYDEIYHHVFVHSAIEHSGCLIYEVHGKEHLLVVVNAKSEPYQFENAGNLAMLVTNS
                     RSKEDNVLNDISLAVLSVL"
     gene            complement(4476..6434)
                     /gene="ligA"
                     /locus_tag="VQ862_001855"
     CDS             complement(4476..6434)
                     /gene="ligA"
                     /locus_tag="VQ862_001855"
                     /EC_number="6.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent DNA ligase LigA"
                     /protein_id="HET3116153.1"
                     /translation="MNKRMNELVALLNRYATEYYTSDNPSVSDSEYDRLYRELVELET
                     AYPEQVLADSPTHRVGGKVLDGFEKYSHQYPLYSLQDAFSREELDAFDARVRKEVAHP
                     TYICELKIDGLSISLTYEKGILVAGVTRGDGSIGENITENLKRVKDIPLTLPEELDIT
                     VRGECYMPRASFDQVNQARQENGEPEFANPRNAAAGTLRQLDTAVVAKRNLATFLYQE
                     ASPSTRDSQEKGLKYLEQLGFVVNPKRILAENIDEIWNFIQEVGQERENLPYDIDGVV
                     IKVNDLASQEELGFTVKAPKWAVAYKFPAEEKEAQLLSVDWTVGRTGVVTPTANLTPV
                     QLAGTTVSRATLHNVDYIAEKDIRKDDTVIVYKAGDIIPAVLRVVESKRVSEEKLDIP
                     TNCPSCNSDLLHFEDEVALRCINPRCPAQIMEGLIHFASRDAMNITGLGPSIVEKLFA
                     ANLVKDVADIYRLQEEDFLLLEGVKEKSAAKLYQAIQASKENSAEKLLFGLGIRHVGS
                     KASQLLLQYFHSIENLYQADSEEVASIESLGGVIAKSLQTYFATEGSEILLRELKETG
                     VNLDYKGQTVVADAALSGLTVVLTGKLERLKRSEAKSKLESLGAKVTGSVSKKTDLVV
                     VGADAGSKLQKAQELGIQVRDEAWLESL"
     gene            complement(6527..7705)
                     /locus_tag="VQ862_001856"
     CDS             complement(6527..7705)
                     /locus_tag="VQ862_001856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001083019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HET3116154.1"
                     /translation="MNRYAVQLISRGAINKMGNMLYDYGNSVWLASMGTIGQTVLGMY
                     QISELVTSILVNPFGGVISDRFSRRKILMTADLVCGILCLAISFIRNDSWMIGALIVA
                     NIVQTIAFAFSRTANKAIITEVVEKDEIVIYNSRLELVLQVVGVSSPVLSFLVLQFAS
                     LHMTLLLDSLTFFIAFVLVAFLPKEEAKVQEKKAFTGRDIFVDIKDGLHYIWHQQEIF
                     FLLLVASSVNFFFAAFEFLLPFSNQLYGSEGAYASILTMGAIGSIIGALLASKIKANI
                     YNLLILLALTGVGVFMMGLPLPTFLSFSGNLVCELFMTIFNIHFFTQVQTKVESEFLG
                     RVLSTIFTLAILFMPIAKGFMTVLPSVHLSSFLIIGSGVIILSCISFIYVRTHFEKLI
                     "
     gene            complement(7785..8648)
                     /locus_tag="VQ862_001857"
     CDS             complement(7785..8648)
                     /locus_tag="VQ862_001857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012291596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE/MutR family transcriptional regulator"
                     /protein_id="HET3116155.1"
                     /translation="MEHLGKVFREFRTSGNYSLKEAAGESCSTSQLSRFELGESDLAV
                     SRFFEILDNIHVTIENFMDKARNFHNHEHVSMMAQIIPLYYSNDIAGFQKLQIEQLEK
                     SKSSTTPLYFELNWILLQGLICQRDASYDMKQDDLDKVADYLFKTEEWTMYELILFGN
                     LYSFYDVDYVTRIGREVMEREEFYQEISRHKRLVLILALNCYQHCLEHSSFYNANYFE
                     AYTEKIIDKGIKLYERNVFHYLKGLALYQKGQCKEGCKQMQEAMHIFDVLGLPEQVAY
                     YQEHYEKFVKS"
     gene            complement(8651..10552)
                     /locus_tag="VQ862_001858"
     CDS             complement(8651..10552)
                     /locus_tag="VQ862_001858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000584877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HET3116156.1"
                     /translation="MIILQANKIERSFAGEVLFDNINLQVDERDRIALVGKNGAGKST
                     LLKILVGEEEPTSGEINKKKDISLSYLAQDSRFESENTIYDEMLHVFNNLRRTERQLR
                     QMELEMGEKSGEDLDKLMSDYDRLSENFRQAGGFTYEADIRTILNGFKFDESMWQMKI
                     AELSGGQNTRLALAKMLLEKPNLLVLDEPTNHLDIETIAWLENYLVNYSGALIIVSHD
                     RYFLDKVATITLDLTKHSLDRYVGNYSRFVELKEQKLVTEAKNYEKQQKEIAALEDFV
                     NRNLVRASTTKRAQSRRKQLEKMERLDKPEAGKKAANMTFQSEQTSGNVVLTVENTAI
                     GYDGEVLSQPINLDLRKMNAVAIVGPNGIGKSTFIKSIVDQIPFIKGEKRFGANVEVG
                     YYDQTQSKLTPSNTVLDELWNDFKLTPEVEIRNRLGAFLFSGDDVKKSVGMLSGGEKA
                     RLLLAKLSMENNNFLILDEPTNHLDIDSKEVLENALIDFDGTLLFVSHDRYFINRVAT
                     HVLELSENGSTLYLGDYDYYVEKKVTAEMSQTEEASTSNQAKEASPVNDYQAQKESQK
                     EVRKLMRQIESLEAEIEELESQSQAISEQMLETNDADKLMELQAELDKISHRQEEAML
                     EWEELSEQV"
BASE COUNT         3221 a         2370 c         1916 g         3247 t
ORIGIN      
        1 tgtactattc tagtttcaat atactataat accaaaaagt tcgtattttt tctataatta
       61 ttattatttt atagcaaaaa aataaaacca ggaaaacaat ttcctgattt tacacgttat
      121 ttcacatcaa aaacaatgga tttgacattt gtcatcgctt caatgctata tttaatccct
      181 tgcactccag ctccagaacc tttgacacca aggaacggga aattatctgg accacgctgg
      241 gttttattat taatgtggac tgtacctact tcaagttttt cagcaatttc aaaggctttt
      301 ttgaaatcat ttgtaaagac tgatgattga aggccgaatt cagattcgtt ggcaaaggca
      361 atagcttcct ctacactagc cacacgaatg attggtaaaa caggaccaaa tggctcttcc
      421 catgccactt tcatatcttt tgtaacttgg tcaaaaagca ctggccagag gagattgccc
      481 tcacgtttga ttggtgtaag agcctgagcc tctttttctt gtgcatcctc aatcaagccc
      541 caaatgaagt cggctgaagc attgtcaata acaggtgtaa tatcagcatt gtcaaatgga
      601 tcaccaactg ttaatttaga aacttcttcc tgaagcaaag tagctaattt atctgctaca
      661 ctttcgagaa caatgacacg tttaatggcc gtgcaacgtt gtcctgagta gctaaaggct
      721 cccgcaacaa tttgcttggc agcatgttcc aaatctgcat cttctagtac aagagctgca
      781 tctttcccac caagttccaa catgatagga cgcataccag ctaaacgacc aatacgttct
      841 ccaataggag ttgaacctgt aaagttgatg aagttgactt ctttgtgctc aatgatataa
      901 tccccaattt ctgaaccacg acctgtaatg gtgttgaaaa cacctgccgg aatccctgct
      961 tcttcaaatg ctttagccaa caagagtcca gaaatggaac cttgtgttgg tggcttaaac
     1021 atgaccacat tccctgcaat caaggcaggt gcaattttag aagcagataa attaactgga
     1081 taattaaagg gagcaatcgc tagcacgata ccaactggtt cacgacggac aacagccagt
     1141 ttgtttttac ttgctgcctc aaaaccacca ccttccattg cttgtccagt gatacggaga
     1201 ccttcctcag cagcataacg aatcaagtct gctgtacgca ctacttctcc aattgctgct
     1261 ttaatccctt ttgctacttc tttggcaagg atagtaccaa tttcttcctt atcgcgttct
     1321 aaaatagctg ctgttttatg caaataagcc gcacgttcaa ttgctgataa agctcgccat
     1381 gctggcaggg ctgcacgcgc agcttgcata gcctcatcag cttcagtctg agtcatggct
     1441 ggaactgtac ccaattcttc ttgattgatt ggtgaataaa tcgtaatttc ttgttcagat
     1501 gatttccatt ttccatttac taaattctga tatcttgtca aattcttgtc ctcctgaaaa
     1561 tgattaagat atattttacc aaattttcag aaaaccacaa ccctttttgc gaaatttttg
     1621 agattatttt cacaagcttg atttttcaaa gtatactcaa taaaaataaa aaaatccact
     1681 acgtcaaggc gaggctaatg tggtttgaag aaattttcga agagcgtgaa tgagtatcat
     1741 ctatagtaaa ataaaaaaac tgaacaattt ggtttgggac agtcaaacca atttctcaca
     1801 atgttttaga aacacgggtg tgctattcca atttcaggct actataactg tcatagattg
     1861 ctgaaacaaa gtctaggtaa aagtcttcat aataaaaaga cctcctatca aatgttcaaa
     1921 aactttgata ggaggtcttg tttcgtgaaa atatttatca aattttctat acaagtgagc
     1981 tgttagccag gttctttcta ttctttcaat ttcaatgaat ggatttttta ccaatactca
     2041 taactgggaa tttttctgtg taaaaatagc gagatagatg gtatttataa aacactcaag
     2101 acagctagac taatatcatt taaaacatta tcttcttttg agcgactgtt ggttaccaac
     2161 atagctaaat ttcctgcatt ttcaaattga tagggttctg atttagcatt cacaaccacc
     2221 aagaggtgtt ctttgccgtg aacttcatag ataaggcagc cgctatgttc aatcgccgaa
     2281 tgcacaaaga catgatggta aatttcatca tagctagagt aagaaaaggc accagttttt
     2341 gtcttcaatc ggatgacttg acggataaac tcaatactgt cttgacgctc attaatcaag
     2401 ttccagttca cttggttcac actgtcagga gcattatagc tattcatcgc acgctctcta
     2461 tcatcatggg tcaactcacc attttcacca gtcgcaacca gtttggtacg accaaattct
     2521 tgaccgattt ccataaaggc catcccctgc atgagcagat tcatggctgt ggcagtttcg
     2581 accttgcgca tgatttgctc tgaactttgg tctggatgaa gggttgccaa taaatcgtga
     2641 agattgtaat tgtcatgggc ttctacatag ttaagcacct gatttggatg tgtatagctt
     2701 cctaattcac gacttcctag gattgcttta gctagaattg gctctgtcgc agcaccactg
     2761 acaaaacctg acttgatagc accataaact tctccccctt tgacagcatc gcgctgattg
     2821 tcattaaaga aaccaatatt tggcatctgg taggcattgt ccttcttggc cttatcataa
     2881 ggggcaagac ctgttcccat atcccatcct tctccataga ggataatgtt ggagtcgatt
     2941 tcatccaagc tttgacgaat catctgcatg gtcttgacat catgaatccc catcaagtca
     3001 aaacggaagc cgtcaatatt atattcctgc acccagtata gaagagaatc aatcatatac
     3061 ttgcgaaaca tttcgtgttc actggctgtt tcatttccaa cacccgttcc attctggaag
     3121 gtaccatctg gattcatacg ataatagtaa tcagggactg ttgtttggaa tggtgcatca
     3181 acaactgaga aggtatggtt atagactaca tccataatga ctccaatacc cgcatcgtga
     3241 taagcttgaa ccatcacctt caaatcacga atgacctgag ctggatcatc tggattagtt
     3301 gaaaaactag tttctggcgc gttatagttt tgtggatcat aaccccagtt gtaggttaca
     3361 tttccatcct catcgtattc tttatgacgg tctgcaattg gttgcaattg aacataattg
     3421 tagcccagct tcttgatgta atcaaaagca gttgactggc cgtattggtt aactgttcca
     3481 gcctgagcag cacccaagaa agttcctcga agatgttcat ctacacccga tgtaggtgat
     3541 ttagtcaaat cacgaatgtg catttcacag ataactgcct tacatggatt ttccaagcgc
     3601 caagtagcct ccgaaccgtg cttaacctcg aagttttcaa cttgcttttc tacatggctc
     3661 agaatagctg aacgtttgcc atcagggctg gtcgcgattg tataaggatc acgtgtcagt
     3721 gtttggtgat gagggaattg gacttgatac tgataagcct tacctaccaa atcttcctca
     3781 acatccaaac tccagacacc gattgtattg tccttatgat tataagagta gctattgcct
     3841 cttttcatct caaaagtctt ccaaacgggt gcatcattag cagctgattc ataaacgaca
     3901 acttgcactt ctgtcgctgt aggtgaccag agggaaaaat gagcctgatt gtcctctaca
     3961 cggcaaccca attctccttg gtaaccccaa tgatggtcaa aactagcact gttaatggcc
     4021 ttatcaaagg caaaaggatt ttgattttta tagaaaggac tggcaatagc aggattttca
     4081 gagtaataaa tcctatcatc gccttccaaa atccagactt ctgttaatag gggatagtga
     4141 ttaaaacgga tagaatattc tttactagtt tgacctgtat gaaccacaaa attcaagctt
     4201 tctataacat gtgaacttgg gtgttcaaag ctaaataaag ctccaaaata atcttctttg
     4261 taggttagca aatcaattcg ttgatcctga ctttttacaa aggagcaagt gtcatattca
     4321 ccattcttgc gatggtaatg aatgcgcata gggtagttat acatttttta tttttccttt
     4381 ttactttgtt tctatttcac taataaattt ttgtcaatct cgtctcaatt aacagacata
     4441 gtcatattct ctaaactctg tttttaaacg atccattaca aactttctag ccatgcctca
     4501 tctctgacct ggataccaag ttcttgtgct ttttgcagtt tacttccagc gtctgcacct
     4561 accacgacga ggtcggtctt tttagaaaca ctacctgtca ctttggcacc cagactttcg
     4621 agtttacttt tagcttctga gcgcttgagt cgttccaatt ttcctgtcaa taccacggtc
     4681 aaacctgaca aggccgcatc cgctactacc gtctgtcctt tatagtccag attgacccca
     4741 gtttctttca attctctgag cagaatttca gagccttctg tcgcaaaata agtctgaaga
     4801 cttttggcaa tcacgccacc tagactttca atactagcca cttcctctga atctgcctga
     4861 tacagatttt caattgaatg gaaatattga agtaaaagct gactagcctt gcttccgaca
     4921 tgacgaattc ccaaaccaaa taagagcttc tcggcagaat tttcctttga tgcttggata
     4981 gcctgataca gtttagcagc ggacttttcc ttaaccccct ctaaaaggag gaaatcctct
     5041 tcttgcaaac gataaatatc cgccacatcc ttgactaaat tagcagcaaa aagcttctca
     5101 acaatagatg gaccaaggcc tgtaatattc atagcatcac gagaagcaaa gtgaatcaag
     5161 ccttccatga tttgagcagg gcaacgcgga ttgatacaac gtagggccac ttcatcttca
     5221 aagtgcaaca agtcagagtt acaacttgga cagtttgtag ggatatctag tttttcttca
     5281 gaaacccgtt tggactctac cacacgtaaa acggcaggga tgatgtcacc agccttatat
     5341 acaatgaccg tatcgtcttt tcggatatct ttttcagcaa tataatctac attgtgcagg
     5401 gtcgcacggc taacagtcgt accggcaagt tgtactggtg ttagattagc agttggagtt
     5461 acaacaccgg tacggccaac tgtccagtca actgataaga gttgagcttc tttttcttca
     5521 gcagggaact tgtaggctac tgcccacttt ggagccttaa cggtaaaacc aagttcttct
     5581 tgacttgcta ggtcgttgac cttgattacc actccatcaa tatcgtaagg tagattttcc
     5641 cgttcctgtc ctacttcttg gataaaattc cagatttcat ctatgttttc agccaagatt
     5701 cgcttaggat tgaccacaaa acctagttgt tctaggtact tcaaaccctt ttcttggcta
     5761 tcacgagttg aaggactggc ttcttgatag agaaacgttg caagattacg ctttgcaact
     5821 actgctgtat ccaactgacg cagagttcct gctgccgcat tacgaggatt agcaaattca
     5881 ggctctccat tttcttggcg cgcttggtta acttggtcaa aggaagcgcg tggcatgtaa
     5941 cattccccac gaactgtgat atctagttct tctggcaaag tcaaagggat gtccttaaca
     6001 cgcttgaggt tttctgtgat attttcacca attgaaccat ctccacgtgt taccccagca
     6061 accaaaatcc ccttttcata agtcagcgag atagataagc catcgatttt cagctcacaa
     6121 atataggtcg gatgagccac ttccttacga acacgcgcat caaaagcatc tagctcctca
     6181 cgtgaaaaag catcctgcaa actataaaga ggatactgat gactgtattt ttcaaaacca
     6241 tctaaaacct tgccaccaac acgatgagtc ggactgtctg ctagcacttg ctctggataa
     6301 gcagtttcta actcgaccaa ctcacggtaa aggcggtcat actcactgtc tgaaaccgag
     6361 ggattatcgc tggtatagta ctcagtcgca tagcgattga gcaaagcgac taactcattc
     6421 attcttttat tcataagacc attttaccat aaaacaagcc ctcctcacaa acgagaaggg
     6481 cggaaaaaac acttagtttg aaattatttt tgaaactcaa gcaaccttat atcaattttt
     6541 caaaatgagt tcgaacataa ataaacgata tacaagacaa gatgataaca ccacttccaa
     6601 ttatcaggaa agaagagaga tgtacacttg gcaagactgt cataaatcct tttgcaatag
     6661 gcataaatag aatagctaag gtaaaaattg tactcagtac tctcccaaga aattcgctct
     6721 caaccttggt ttgtacttga gtaaaaaagt gaatattaaa aatcgtcata aacaattcac
     6781 aaactaaatt tccagaaaag gaaagaaaag ttggaagtgg taatcccatc ataaaaactc
     6841 cgacacctgt caaagccagt aaaatcaaaa gattataaat attagcttta attttactag
     6901 ctagaagagc cccaatgatg gaaccaatag cccccatagt taaaatactt gcataggctc
     6961 cttctgaccc gtaaagctga ttcgaaaagg gaagtagaaa ttcaaaagct gcaaaaaaga
     7021 aattaacgct ggaagctacc agcaaaagga agaaaatttc ttgctgatgc cagatatagt
     7081 gtaacccatc cttgatatct acaaaaatat ctctcccagt aaaagccttt ttctcttgaa
     7141 cttttgcttc ctcttttgga aggaaagcca ctagaacaaa agcaatgaaa aaagtcagcg
     7201 agtctagcag tagcgtcata tggagacttg caaactgtaa aacaaggaag gaaagaacag
     7261 gagagctaac acctacaacc tgcaaaacca gctctaagcg agaattatag atcacaatct
     7321 catctttctc caccacttca gttatgatag ctttattggc tgtgcgagaa aaggcaaaag
     7381 caatagtctg cacaatgtta gcaacaatca aagcgccaat catccagcta tcattcctta
     7441 tgaaagaaat agccagacaa agaatcccac aaacaagatc tgccgtcatt aaaatcttac
     7501 gacgagaaaa acggtctgaa ataactccgc caaagggatt gacgagaata gatgtgacga
     7561 gctcagaaat ctgatacatt cctaaaactg tctgtcctat agtccccata gaagccaacc
     7621 agacactatt tccataatca tagagcatat ttcccatttt attgatagcc ccacggctaa
     7681 tcaactgcac tgcatagcga ttcatattaa agctcctctc aaattttgaa actattgtat
     7741 caaaaccgaa aggagctttt tattttttcc cttatttggg aaaattaact tttgacaaat
     7801 ttttcgtagt gttcctgata ataggctact tgctctggaa gacctaacac atcaaaaata
     7861 tgcatggcct cttgcatctg cttacagcct tctttacact gtcctttttg atataaggcc
     7921 aaacctttta aataatggaa aacattacgc tcataaagct taataccttt gtcaataatc
     7981 ttctctgtat aagcctcaaa atagttggca ttataaaaag aagaatgctc taaacaatgc
     8041 tggtaacaat tgagggccaa aattaacact aatctcttat ggcgactaat ctcttggtaa
     8101 aattcctccc tctccataac ttctctacca atccgagtga catagtctac atcgtagaaa
     8161 ctatagaggt taccgaaaag aatcaactca tacatggtcc attcttctgt tttgaagaga
     8221 taatctgcta ccttatccaa atcatcctgc ttcatatcat aactcgcatc tctttgacaa
     8281 atcagacctt gtagcaaaat ccagttcagc tcaaaataaa ggggagtcgt cgaactctta
     8341 gacttttcaa gttgttctat ttgaagcttt tgaaaacctg caatatcgtt tgaatagtaa
     8401 agtgggataa tctgtgccat catagacaca tgttcatgat tatgaaaatt ccttgcctta
     8461 tccatgaaat tttcgattgt tacatgaatg ttatccaaaa tctcaaagaa acgggagact
     8521 gccaggtcag actccccaag ctcaaagcga gataactgag aggtagagca ggattcgcct
     8581 gctgcttcct ttaaagaata atttccactt gttcgaaatt cacgaaatac ttttccaaga
     8641 tgttccatct ttacacctgc tctgataatt cttcccactc aagcatagct tcttcctgac
     8701 gatggctgat tttgtccagc tcagcctgta attccatgag tttgtcggca tcgtttgttt
     8761 ccaacatttg ttcagaaatg gcttggcttt gactttctag ctcttcaatt tcagcttcta
     8821 gactttcgat ttgtcgcatg agtttgcgaa cttctttttg actttctttc tgggcctgat
     8881 agtcattgac tggacttgct tcctttgctt gattgctagt tgaagcttcc tcagtctgac
     8941 tcatttctgc tgttactttc ttctcaacat agtagtcgta atctccaagg tagagagttg
     9001 aaccattctc agacaattcc aaaacatgag ttgccacacg attgataaag taacgatcat
     9061 gactgacaaa aagcaaggta ccatcaaagt caatcaaggc attttctagc acttccttac
     9121 tatcaatatc caagtggttg gtcggctcat ccagaatcaa aaagttattg ttttccatag
     9181 acaatttggc taaaagcaaa cgagcttttt cgccaccaga tagcatgccg actgattttt
     9241 taacatcatc tcctgagaaa aggaaggctc caagacggtt gcggatttca acttctggtg
     9301 tcagtttgaa atcattccag agttcatcca gcaccgtatt acttggtgtc agcttgcttt
     9361 gggtttggtc atagtaacca acctcaacat tagcgccaaa gcgcttttct cccttgataa
     9421 acggaatttg atccacgatt gatttgataa aggttgattt tccgatacca ttgggaccaa
     9481 cgatagcgac agcattcatc ttacgaagat ctaggttgat aggttgtgac aagacttccc
     9541 cgtcataacc aatagcagta ttttcaacag tcaaaacaac attgcccgac gtttgttcag
     9601 actggaaggt catgttggct gctttcttgc cagcttcagg cttgtccaaa cgctccattt
     9661 tttctagttg tttacggcga gattgagcac gtttagtcgt tgaagcacga actagattgc
     9721 gattgacaaa gtcttccaga gcagcgattt ccttctgttg cttttcatag ttttttgcct
     9781 cagtaactag cttttgctcc ttcaattcga caaaacgaga gtaattcccc acatagcgat
     9841 ccaaggaatg cttggtcaaa tctagcgtaa ttgtcgcaac cttgtccaag aaataacggt
     9901 cgtggctgac gataatgagg gcaccgctat agtttaccaa gtaattctct agccaggcga
     9961 tggtttcaat atccaagtgg ttagttggct cgtccaagac caagagattg ggcttttcaa
    10021 ggagcatttt ggcaagtgcc aaacgagtat tttgaccacc agaaagctca gcaattttca
    10081 tctgccacat agactcgtca aacttgaatc cattcaaaat cgttcgaata tcagcttcat
    10141 aggtaaagcc acctgcttgg cgaaaattct cagataagcg gtcataatct gacatcagtt
    10201 tatccaaatc ctcaccagac ttttcaccca tctccagctc catctgacgc agttgtctct
    10261 ccgtccgacg caaattatta aagacatgaa gcatttcatc gtagatggta ttttcagact
    10321 caaaacggct atcttgggct aggtaagaca gagaaatatc ttttttctta ttgatttctc
    10381 cgctagttgg ctcctcttct ccaactaaaa tcttcaaaag agtagactta cctgcaccat
    10441 ttttcccaac aagggcaatc cgatctcgtt catcaacctg caggttgata ttatcgaaaa
    10501 gaacctctcc tgcaaaagaa cgttcaattt tattagcttg taaaataatc ataagagtag
    10561 tatagcatgt ttccctaagg cattcaagat aatcgtaagt cttttagtac aacttttata
    10621 acataaaata aactaaatta tgtatatttt atattagatt cttcactatc ttgttggatt
    10681 ttctaaccag ctaatcttgt ttcaaatagt tatcgcacaa gcctattatt taattctttt
    10741 cattatttac gtac
//
LOCUS       DAVBOD010000068        10686 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 640-05
            SAMEA1012484-rid20186543.denovo.068, whole genome shotgun sequence.
ACCESSION   DAVBOD010000068 DAVBOD010000000
VERSION     DAVBOD010000068.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012484
            Sequence Read Archive: ERR059358
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10686)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10686)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979948.1
            Genome Coverage       :: 595x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:03:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,266
            CDSs (total)                      :: 2,219
            Genes (coding)                    :: 2,091
            CDSs (with protein)               :: 2,091
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 71 of 128
            Pseudo Genes (incomplete)         :: 50 of 128
            Pseudo Genes (internal stop)      :: 33 of 128
            Pseudo Genes (multiple problems)  :: 22 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10686
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012484-rid20186543.denovo.068"
                     /strain="NIG 640-05"
                     /db_xref="taxon:1313"
     gene            85..366
                     /locus_tag="VQ862_001859"
     CDS             85..366
                     /locus_tag="VQ862_001859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000380698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 1 glycosylhydrolase"
                     /protein_id="HET3116157.1"
                     /translation="MDTPDENGYVADDYRITYLEAHIKAMRDAIYQDGIDLLGYTTWS
                     CIDPVSAGTGEMNKRYGFIYVDRDNVGNGTLKRSKKKSFYWYMSFIAMV"
     gene            498..1442
                     /gene="manA"
                     /locus_tag="VQ862_001860"
     CDS             498..1442
                     /gene="manA"
                     /locus_tag="VQ862_001860"
                     /EC_number="5.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-6-phosphate isomerase, class I"
                     /protein_id="HET3116158.1"
                     /translation="MSEPLFLQSVMQEKIWGGTKLRDEFGYDIPSEKVGEYWAISAHL
                     NGVSKVANGRYEGTDLATLYAEHRELFGNRPEPVFPLLTKILDANDWLSVQVHPDDAY
                     GLEHEGELGKTECWYIIAADEGSEIIYGHNAKSKEELRQQIEDKNWDALLTKVPVKAG
                     DFFYVPSGTMHAIGAGILILETQQSSDTTYRVYDFDRKDDKGNLRELHLEKSIDVLNI
                     GEPANSRPVTIKADDLRSTLLVSNDFFAVYKWEITGKVNFEKTADYSLLSVLAGQGQL
                     TVDGKNYPIQKGRHFILPSDVEAWTLEGQDLELIVSHP"
     gene            complement(1433..2937)
                     /locus_tag="VQ862_001861"
                     /pseudo
     CDS             complement(1433..2937)
                     /locus_tag="VQ862_001861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844893.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="sodium-dependent transporter"
     gene            3042..3782
                     /locus_tag="VQ862_001862"
     CDS             3042..3782
                     /locus_tag="VQ862_001862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000274781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HET3116159.1"
                     /translation="MYHIKEAAQLSGVSVKTLHHYDKIGLLVPLKSENGYRTYSQEDL
                     ERLQVILYYKYLGFSLEKIAELLKEERTDLLPHLTRQLDYLTRERQHLDTLISTLQKT
                     IQEQKGERKMTIEEKFTGFSYQDNQKYHQEAVEKYGQEVMGQALERQKGHEDEATAAF
                     NQVFQTLAQNLQVGLPATATENQEQAAKLLQAIRTYGFDCSIEVFGHIGKGYVYNPEF
                     KENIDKFGSETAQYTSDAIAAYVQTNAE"
     gene            complement(3811..4266)
                     /locus_tag="VQ862_001863"
     CDS             complement(3811..4266)
                     /locus_tag="VQ862_001863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001081770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HET3116160.1"
                     /translation="MNRREAVEFVNMCMIKNGDKVLVQDRVSPDWSGITFPGGHVERG
                     ESFVDAVIREVKEETGLIISKPQLCGIKNWYDDKDYRYVVLFYKTEHFTGELQSSDEG
                     KVWWEDFENLSHLKLATDDMSDMLRVFLEEDLSEFFYYKNGDDWLYDLK"
     gene            complement(4286..5461)
                     /locus_tag="VQ862_001864"
     CDS             complement(4286..5461)
                     /locus_tag="VQ862_001864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HET3116161.1"
                     /translation="MKHFDTIVIGGGPAGMMATISSSFYGQKTLLIEKNRKLGKKLAG
                     TGGGRCNVTNNGSLDNLLAGIPGNGRFLYSVFSQFDNHDIINFFTENGVKLKVEDHGR
                     VFPASDKSRTIIEALEKKITELGGQVATQIEIVSVKKVDNQFVLKSADQTFTCEKLIV
                     TTGGKSYPSTGSTGFGHEIARHFKHTITDLEAAESPLLTDFPHKALQGISLDEVTLSY
                     GKHVITHDLLFTHFGLSGPAALRMSSFVKGGEVLSLDVLPQLSEKDLVTFLEENREKS
                     LKNALKTLLPERLAEFFVQGYPEKVKQLTEKEREQLVQSIKELKIPVTGKMSLAKSFV
                     TKGGVSLKEINPKTLESKLVPGLHFAGEVMDINAHTGGFNITSALCTGWVAGSLHYD"
     gene            complement(5520..6365)
                     /locus_tag="VQ862_001865"
     CDS             complement(5520..6365)
                     /locus_tag="VQ862_001865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HET3116162.1"
                     /translation="MTWKIIADSGCDYRQLPTPAINTTFVSVPLTIQVADQVFVDDAS
                     LDIDQMMETMYATAEASKSACPSPDDYLRAFEGAKNIFLVTITGTLSGSHNSAQLAKN
                     IYLEDHPDTKIHVIDSLSAGGEVDLLVEKLNDLIDQGLSFEEVVEAITAYQEKTKLLF
                     VLAKVDNLVKNGRLSKLIGTVVGLLNIRMVGKASETGTLELLQKARGSKKSVQAAYDE
                     LVKAGYAGGRIVMAQRNNEKCCQQLSERIRETFPQADIKILPTSGLCSFYAEEGGLLM
                     GYEID"
     gene            6490..7047
                     /locus_tag="VQ862_001866"
     CDS             6490..7047
                     /locus_tag="VQ862_001866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000003900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HET3116163.1"
                     /translation="MSERRISEKSLENLRKSNQESNLLTREAIETALLQLLEKKELTK
                     ISISELVKRAGVSRAAFYRNYDSKEEILESVFKRTVHNIMEQLHHYDLKTDLYLVWVH
                     LFREARKEARVIQLALDYHLEKIFVQAMQEFLEKYHGKSKGVSSYLHSFWSSAIVSVL
                     LKWIKDGMKVPAEKIADLGLPFFKK"
     gene            7066..7533
                     /locus_tag="VQ862_001867"
     CDS             7066..7533
                     /locus_tag="VQ862_001867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000138511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine/deoxycytidylate deaminase family
                     protein"
                     /protein_id="HET3116164.1"
                     /translation="MTEKRLAWDEYFAAQALLIANRSTCKRAKVGAILVKDNKVISTG
                     YNGSVSGTEHCIDHECLVIEGHCVRTLHAEVNAILQGAERGVPKGFTAYVTHFPCLNC
                     TKQLLQVGCKRVVYINQYRMDDYAQYLYQEKGTELTHLPLETVQTALKEADLM"
     gene            7622..8251
                     /gene="upp"
                     /locus_tag="VQ862_001868"
     CDS             7622..8251
                     /gene="upp"
                     /locus_tag="VQ862_001868"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002883819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil phosphoribosyltransferase"
                     /protein_id="HET3116165.1"
                     /translation="MGKIEVINHPLIQHKLSILRRIDTSTKAFRELVDEIAMLMGYEV
                     LRDLPLEDVEIETPITKTVQKQLAGKKLAIVPILRAGIGMVDGLLSLVPAAKVGHIGM
                     YRDEETLQPVEYLVKLPEDIDQRQIFVVDPMLATGGSAILAVDSLKKRGASNIKFVCL
                     VSAPEGVKALQEAHPDVEIFTAALDERLNEHGYIVPGLGDAGDRLFGTK"
     gene            8425..9015
                     /gene="clpP"
                     /locus_tag="VQ862_001869"
     CDS             8425..9015
                     /gene="clpP"
                     /locus_tag="VQ862_001869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000613477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease proteolytic subunit
                     ClpP"
                     /protein_id="HET3116166.1"
                     /translation="MIPVVIEQTSRGERSYDIYSRLLKDRIIMLTGPVEDNMANSVIA
                     QLLFLDAQDSTKDIYLYVNTPGGSVSAGLAIVDTMNFIKADVQTIVMGMAASMGTVIA
                     SSGAKGKRFMLPNAEYMIHQPMGGTGGGTQQTDMAIAAEHLLKTRNTLEKILAENSGQ
                     SMEKVHADAERDNWMSAHETLEYGFIDEIMANNSLN"
     gene            9094..9342
                     /locus_tag="VQ862_001870"
     CDS             9094..9342
                     /locus_tag="VQ862_001870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000462128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbG family protein"
                     /protein_id="HET3116167.1"
                     /translation="MFEKVNRSGLIIYLYYNRDAKKLQDYGDITYHSKKHRYLQLYVP
                     TQEVEQLVGRLSKEKFIKKVRVCHIQELETPFVGNLYR"
     gene            9443..10603
                     /locus_tag="VQ862_001871"
     CDS             9443..10603
                     /locus_tag="VQ862_001871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HET3116168.1"
                     /translation="MKKKFALSFVALASVALLAACGEVKSGAVNTAGNSVEEKTIKIG
                     FNFEESGSLAAYGTAEQKGAQLAVDEINAAGGIDGKQIEVVDKDNKSETAEAASVTTN
                     LVTQSKVSAVVGPATSGATAAAVANATKAGVPLISPSATQDGLTKGQDYLFIGTFQDS
                     FQGKIISNYVSEKLNAKKVVLYTDNASDYAKGIAKSFRESYKGEIVADETFVAGDTDF
                     QAALTKMKGKDFDAIVVPGYYNEAGKIVNQARGMGIDKPIVGGDGFNGEEFVQQATAE
                     KASNIYFISGFSTTVEVSAKAKAFLDAYRAKYNEEPSTFAALAYDSVHLVANAAKGAK
                     NSGEIKDNLAKTKDFEGVTGQTSFDADHNTVKTAYMMTMNNGKVEVAEVVKP"
BASE COUNT         3384 a         2105 c         2278 g         2919 t
ORIGIN      
        1 tcttctttaa ttgatttcat attactattg tataatgatt tttgatttta gtttagtatt
       61 atcgtagaaa atggactcgg tgctatggat acaccggatg agaatggtta tgtagcagat
      121 gactatcgga ttacttactt agaggcccac atcaaggcca tgcgagatgc catttaccaa
      181 gatgggattg acttgcttgg ttatacgact tggagctgta tcgatccggt ttcagctggc
      241 acaggggaaa tgaataagcg ctatggcttt atctatgtag atcgagataa tgtaggaaat
      301 gggactctca aacgtagcaa gaagaagtcc ttctattggt acatgtcatt tatagcaatg
      361 gtgtaagcat cgagtagagc acatttgttt actattttta taaaatcttc tccctgcttt
      421 ataagatgta aaaaagagtt caaatggaac tctttttttg ctataatgag gggagaaaaa
      481 tcagacagga gattaagatg tcagaaccat tatttttaca atcagttatg caagaaaaaa
      541 tctggggtgg taccaagcta cgtgatgagt ttggctacga catcccaagt gaaaaagtcg
      601 gagagtactg ggctatctca gctcatctaa atggtgtttc taaagttgcc aatggtcgtt
      661 acgagggaac agatcttgct actttgtatg cggaacaccg tgaattattt ggcaatcgtc
      721 cggaacctgt atttccactt ttgaccaaga tcctcgatgc caacgactgg ctcagtgtcc
      781 aagttcaccc agacgatgct tatggactcg agcatgaagg cgaacttgga aaaacagaat
      841 gttggtacat cattgcagca gatgaaggtt cagagattat ctacggtcac aatgccaagt
      901 caaaagaaga actccgccag caaatcgagg ataagaactg ggatgcgctg ttgacaaaag
      961 tgccagttaa agcaggagat ttcttctatg taccaagcgg taccatgcac gctatcgggg
     1021 cgggtatctt gattcttgaa acccagcagt ctagcgatac cacttaccgt gtctatgact
     1081 ttgaccgtaa ggatgacaag ggcaatttac gtgaacttca ccttgaaaaa tctatcgatg
     1141 tcttgaacat tggtgaaccc gcaaatagcc gtccagtgac aatcaaagca gatgatctac
     1201 gttccactct ccttgtatcc aatgatttct tcgcagttta caaatgggaa attactggaa
     1261 aagttaactt tgaaaagaca gctgactaca gcttgttgag tgtcttggct ggtcaaggtc
     1321 aactaactgt tgacgggaaa aactatccaa tccaaaaagg gagacacttt atcctaccaa
     1381 gtgatgttga agcttggact ctggaagggc aagatttaga attaattgtt agtcatccat
     1441 aaaaaagaaa gggcctgagt tcattactca agtccttttg attacataaa ttgggcgatg
     1501 aagaccacga tgatgattgg aatgacggaa cgaagaaacg aagaaggaag agccagactt
     1561 ggaacagtcc ttgtttccat gctctttcat cgagatggag ttcctccatt gcaagagcct
     1621 ttttaaagat atagcctgta aaaagtgaaa ggaagagagc tccaaatggc atgaggagat
     1681 tggaaaccaa gaagtccata gcgtcaaaga aggtcttacc aaaaatgtga acatccgcca
     1741 tgacaccgta agatagggct gaaggaatgc caaagacaaa ggtcaaaatt tctaaaataa
     1801 cactccattt agcacgcttg ctgttgtcct gattggtgat attgtctaca ttgatttcta
     1861 gcatcacgac agaagaagtg acagtcgcaa agaggaagag gacgtagaaa atggttccaa
     1921 aaggcatctt gtcaaagagt tgaggcaaga cgataaagag caggctgggt cccccttcag
     1981 actggatatt gaagggggat cgagcttgga aaatggctag acctgccatg atggatatcg
     2041 agatattcat ggctacgatg gagattcctg actggactag attggttttc ttgtccaagt
     2101 aagaagcata ggtcaacatg actgtaaccc ctagtgagag ggcaaagaaa gattgtccca
     2161 gagcatagag gagaccagcg ctagtcagtt ttgaaaagtc tggtttgagg aagtaaagaa
     2221 ccccttccat ggcatttggc aaactgagag agcgaccgat gataaaaaca aagacgataa
     2281 agagcagggg catcatgact ttcgaagctc tttcaatctc tttttgaacc ccacgtgata
     2341 caatgaagat attcaatagg ataaaggccg cttgagctcc tagggcaatg gctggatttg
     2401 aaatgattga agtaaataac tgagcataat cacccgttcc accaagttgg aacaatttcc
     2461 caaactcaat acctagatag actagaatcc atcctccgat aacactgtaa aaagataaga
     2521 ggataaagag ggcaaaggcg ccaatccaac cgataaagtt gtacttgtta ttcttgccca
     2581 gttttccaaa ggttttgata gcggaaacgc cagcactacg gccaagggca aactcagcca
     2641 gcaggagagg gaaaccgatt aaaatagtgg aaatgagaaa gattagtaaa aagcctccac
     2701 cgccattagc agcagtcatg tagggaaact tccaaacgga accaagcccg atggccagcc
     2761 agcagatgct agaataaaac caagtttcga cccccattgt gatttttctg acatagttaa
     2821 actctgatct cctttttcaa aataagaaaa agctacttga gttgtcaaat agccttctgt
     2881 ttgattgata gacttgacta tcctatcatg ttttctaagg tctgtcaaga aaatcatttt
     2941 caagttttca cacctttctc aaaaaagtta aaaaattttc tcaaaaacgc ttgactctga
     3001 cctaagggga ggggttatac tatcattgta aggaggaaat catgtaccat ataaaagaag
     3061 ctgcgcagct ttcaggtgtc tctgtcaaga ccctgcatca ctatgacaag ataggactct
     3121 tggtcccctt aaagtcggaa aacggctatc gaacctacag tcaagaggat ttggaacgcc
     3181 ttcaggtcat tctttactac aaatatctag gcttttcttt agagaaaata gcagagctgt
     3241 taaaggaaga aaggacagat ttattgcccc atttgactag gcagttggac tatctaactc
     3301 gcgaaaggca acatctggat accttgattt ccaccttgca aaaaactatt caagaacaaa
     3361 aaggagaaag aaaaatgacc attgaggaaa aattcacggg atttagctat caagacaatc
     3421 aaaaatacca ccaagaagcg gtagagaaat atggtcaaga agtcatggga caagcgctcg
     3481 aacgccaaaa aggtcacgaa gacgaggcta cggccgcctt taaccaagtc tttcaaactt
     3541 tggcacaaaa tcttcaagtt ggtttacctg caacagcaac cgaaaaccag gagcaagcag
     3601 ccaagctctt gcaagccatt cgcacttatg gatttgactg ctctattgag gtattcggtc
     3661 atatcggtaa aggttacgtc tacaacccag agtttaagga aaacattgac aagtttggtt
     3721 ctgaaacagc ccagtacacg tcagatgcca ttgcggctta cgttcagaca aatgcagaat
     3781 aaataggcta ggaatttcct agcctatttt ttacttcaaa tcataaagcc agtcgtcacc
     3841 gtttttgtag taaaagaatt cactgagatc ttcttctaga aacacacgaa gcatatcaga
     3901 catatcatcg gttgcaagtt ttagatgaga aagattttca aagtcctccc accaaacttt
     3961 cccttcgtct gaagactgga gttcaccagt aaagtgttct gtcttgtaaa aaaggacgac
     4021 ataacgataa tccttgtcgt cataccagtt tttgatacca cagagttggg gtttggaaat
     4081 gatcagacca gtttcttctt tcacttcacg aatgacagca tcgacaaagg attcgccacg
     4141 ttcaacatga ccaccaggaa aagtaatgcc agaccagtcg ggactaactc ggtcttggac
     4201 caggacctta tctccgtttt taatcataca catgttaaca aattcgactg cctctcttct
     4261 gttcattctt cacaaccttt aatctttaat cataatgcag acttcccgcc acccagccgg
     4321 tacagagggc agaagtgatg ttaaagccac ccgtgtgggc attgatatcc ataacttcgc
     4381 ctgcaaagtg gaggccaggt accagcttac tttcaagggt tttaggattg atttccttga
     4441 gactgactcc acccttggta acaaaggact ttgcaaggga catttttcca gttacaggaa
     4501 ttttaagttc tttaatggac tggacaagtt gttctcgttc cttttcagtt agttgtttga
     4561 ctttttcagg atatccttgt acaaaaaatt cggccaagcg ttctggtaac aaggttttta
     4621 aagcgttttt caaggatttt tcccgatttt cttctagaaa tgtaaccaag tccttctcag
     4681 aaagttgagg caaaacatcg agtgagagaa cctccccacc tttgacaaag ctagacatgc
     4741 gtagggcagc aggacctgac aaaccaaagt gggtaaagag taaatcatga gtgatgacat
     4801 gcttaccata acttagggtc acctcgtcca gagaaatccc ttgtaaggct ttatgtggaa
     4861 aatctgttaa taaaggactt tcagcagcct caagatcggt gatggtatgc ttaaaatggc
     4921 gagcaatctc gtgaccaaaa ccagtcgaac cagtcgaagg ataagactta ccacctgttg
     4981 tgacaatgag tttctcacaa gtgaaggttt gatccgctga cttaaggaca aactggttat
     5041 ctactttttt aacagaaacg atttctattt gagtagcaac ttgaccacct agttcggtga
     5101 ttttcttttc caaagcttcg ataatagtcc gagacttgtc actggctgga aagacgcgtc
     5161 cgtggtcttc gaccttaagt ttaacaccat tttctgtaaa aaagttgatg atgtcatgat
     5221 tatcgaactg ggagaaaaca ctgtaaagaa agcgtccgtt tccaggaatt ccagctagca
     5281 ggttgtctaa gctaccattg ttggtcacat tgcaacgtcc cccaccagtc ccagctaatt
     5341 tttttccaag tttccgattt ttttcgatga ggagggtttt ctgtccataa aagctactgg
     5401 aaatcgtagc catcatacca gcaggtcccc caccgatgac aatagtatca aaatgtttca
     5461 tagctctatt gtaccacaaa aaaacaagag atgatggtca cctcttgtca agaatgcaat
     5521 taatcaattt catagcccat cagcaaaccg ccctcttctg catagaaact gcagagacca
     5581 gaggttggta gaattttaat atccgcttgt gggaaggttt cacggattcg ctctgagagc
     5641 tgttgacaac atttttcgtt attgcgttgg gccatgacaa tacggccacc agcatatcca
     5701 gcttttacta actcatcata ggcagcttga actgatttct ttgatcccct tgctttttgt
     5761 agcaattcga gagttccagt ttcactagct tttccgacca tacgaatgtt gagaaggcca
     5821 acgaccgtac cgataagctt gctcaaacgg ccgttcttca ccaagttatc gactttggct
     5881 aggacaaaga gcaacttagt tttttcttga taggcagtga tagcttcaac cacttcttca
     5941 aaagacaagc cctggtcaat caagtcattc aatttttcta cgagtaggtc aacttcacca
     6001 ccagcagata aactatcaat cacatgaatc ttagtgtcag gatggtcttc cagataaata
     6061 ttctttgcta gttgagcact attgtgactg ccagaaaggg tacctgtgat ggttactagg
     6121 aaaatgtttt tggcaccttc aaatgctcgc aaatagtcat ctgggcttgg acaagctgat
     6181 tttgaagctt ctgcagttgc atacatggtt tccatcattt ggtcaatatc gagactggcg
     6241 tcatcaacaa agacctgatc agctacttga atggttaagg ggacacttac aaaggttgtg
     6301 ttaatagctg gtgttggcag ttgacgataa tcacaaccag agtcagcaat aatcttccaa
     6361 gtcatagaaa ttctccatct ttgtcagtta tacattgaca aaggttctgt ctttttttac
     6421 aattatatca tgaaaactct tgaaacaaaa gcatcatccg tctgttgtga caagtagaaa
     6481 gaaaatgtta tgtctgaacg tagaatctct gaaaagtctc ttgaaaatct cagaaaatca
     6541 aaccaagaat ccaatttatt aaccagagaa gccattgaaa cagccctctt gcaactcttg
     6601 gaaaaaaagg agctgaccaa gattagtatt tctgaattgg tcaaacgtgc aggtgtttcg
     6661 cgtgcggcct tttatcgcaa ttatgactcc aaagaggaaa ttttagagag cgtctttaaa
     6721 cgaactgtcc acaatattat ggaacagctg catcattacg atttaaagac agacctttat
     6781 ttggtttggg ttcacctttt ccgggaggcc agaaaggaag ctagagtaat tcaattggcc
     6841 ttggattacc atctggaaaa aatctttgtc caagccatgc aggaatttct agaaaaatac
     6901 catgggaaat caaaaggtgt cagctcttat cttcattcct tctggagctc agccatcgtc
     6961 tctgtccttc taaaatggat caaggatggc atgaaggtac cagctgaaaa gattgcagat
     7021 ttaggtttac cattttttaa aaaatagaga aaaaggagaa aagagatgac tgaaaaaaga
     7081 ctggcctggg atgagtattt tgcagcccaa gccctactaa ttgcgaatcg ttccacttgt
     7141 aaacgtgcta aagtgggcgc gattctggta aaagataata aggttatttc cactggttac
     7201 aatggttcgg tgtcagggac tgagcattgt attgatcacg aatgtttggt cattgaaggc
     7261 cactgtgttc gcacccttca cgctgaggtc aatgctatcc ttcaaggtgc tgagcgtggt
     7321 gttcccaaag gctttacagc ctatgtaacc cattttcctt gtctcaactg tacaaaacaa
     7381 ttgcttcagg tcggctgcaa gcgcgtggtt tatatcaacc agtaccgaat ggacgactac
     7441 gcccaatacc tttatcaaga aaaagggaca gaattgaccc atttaccact tgagacagta
     7501 cagacagctc ttaaagaggc tgatctaatg taaaaattat caaaaataaa tggtttagaa
     7561 agatttttaa accgtttttt ggtataatga gaagaataaa ttgaaagaag gaattccaaa
     7621 aatgggaaaa attgaagtta ttaatcaccc actgattcaa cacaaattgt caatcttgcg
     7681 tcgtatagat acttctacaa aagcttttcg tgagctagta gatgagattg caatgttgat
     7741 ggggtatgaa gtacttcgtg atcttccact agaagatgtg gaaatcgaaa caccaattac
     7801 aaaaacagtt caaaaacaat tggcaggtaa gaaattggcc atcgtcccaa tcttgcgtgc
     7861 aggtatcggg atggttgatg gtctcttgag cttggttcca gctgctaaag ttggccacat
     7921 cggtatgtac cgtgatgaag aaacacttca accagttgaa tacttggtga aattgcctga
     7981 ggacattgac caacgtcaaa tttttgtagt agacccaatg ttggcaacag gtggctcagc
     8041 aatcttggct gttgattctc ttaaaaaacg tggcgcatca aatatcaaat ttgtctgcct
     8101 tgtatctgct ccagagggtg taaaagccct tcaagaagct catccagatg tagaaatctt
     8161 tacagcagcc ttggatgaac gtttgaacga acacggttat atcgttccag gtcttggaga
     8221 tgctggagac cgcttgttcg gtacaaaata agatcgaaaa gaagaatgac ttggaaaagt
     8281 atttccagtc acgaaaggag gttgggtttt tgtttctgtc taatgaaagc agagcaaaaa
     8341 tttgaccttt tttgaccaag atattataat agtcttatct tcagtcattt gaccaacaaa
     8401 attaaaactc aaaaggagaa atgaatgatt cctgtagtta ttgaacaaac aagccgtgga
     8461 gaacgttctt acgatattta ctcacgtctt ctcaaagacc gcatcattat gctgacaggt
     8521 ccggttgaag acaatatggc taactctgtt attgcccaat tgcttttctt ggatgcccaa
     8581 gatagtacaa aagatattta cctttatgtc aatacaccag gtggttctgt ttcagctggt
     8641 ttggcaatcg tagataccat gaactttatc aaggcagatg tccaaaccat tgttatggga
     8701 atggctgcat ctatggggac tgtcatcgca tcaagtggag caaaaggcaa acgtttcatg
     8761 cttccaaatg ctgaatacat gattcaccaa ccaatgggcg gtacaggtgg tggtacccaa
     8821 caaactgata tggctatcgc tgcagaacac ttgctcaaaa ctcgtaatac cttggaaaaa
     8881 atcttggctg aaaattcagg tcagtcaatg gaaaaagtcc atgcagatgc agaacgtgat
     8941 aactggatga gcgcccatga aacacttgaa tatggcttta ttgatgaaat tatggccaac
     9001 aattcattga actaatgatg atagaaggca aactcgactg ggtttgcttt ttttggtata
     9061 atagggagag atttcttaga aagaggattt atcatgtttg aaaaagtcaa tcgctctggc
     9121 ttgattatct atctttacta taatcgtgat gccaaaaaac tgcaggatta tggagatatt
     9181 acctatcatt ccaagaaaca tcgttactta caactctatg ttccaactca agaagtggag
     9241 caattggtcg gacgcttgag caaggaaaaa tttattaaaa aagttagggt ttgtcatatc
     9301 caagagttgg aaacaccctt tgtgggcaat ctttatcgat aggaaaacgt tatcatcgaa
     9361 aaagttcaag gaaaacattg acaattttct gataattcgg tatattctta acagactatt
     9421 taagaaataa ggagacaaaa agatgaagaa aaaatttgcc ctatcgtttg tggcgcttgc
     9481 aagtgtagca cttcttgcag cctgtggaga agtgaagtct ggagcagtca acactgctgg
     9541 taactcagta gaggaaaaga caattaaaat cgggtttaac tttgaagaat caggttcttt
     9601 agctgcatac ggaacagctg aacaaaaagg tgcccaattg gctgttgatg aaatcaatgc
     9661 cgcaggtggt atcgatggaa aacaaatcga agtagtcgat aaagataata agtctgaaac
     9721 agctgaggct gcttcagtta caactaacct tgtaacccaa tctaaagtat cagcagtcgt
     9781 aggacctgcg acatctggtg cgactgcagc tgcggtagcg aacgctacaa aagcaggtgt
     9841 tccattgatc tcaccaagtg cgactcaaga tggattgact aaaggtcaag attacctctt
     9901 tattggaact ttccaagata gcttccaagg aaaaattatc tcaaactatg tttctgaaaa
     9961 attaaatgct aagaaagttg ttctttacac tgacaatgcc agtgactatg ctaaagggat
    10021 tgcaaaatct ttccgcgagt catacaaggg tgaaatcgtt gcagatgaaa ctttcgtagc
    10081 aggtgacaca gacttccaag cagcccttac aaaaatgaaa gggaaagact ttgatgctat
    10141 cgttgttcct ggttactata atgaggctgg taagattgta aaccaagcgc gtggcatggg
    10201 aattgacaaa ccaatcgttg gtggtgatgg attcaacggt gaggagtttg tacaacaagc
    10261 aactgctgaa aaagcatcaa acatctactt tatctcaggc ttctcaacta ctgtagaagt
    10321 ttcagctaaa gctaaagcct tccttgacgc ttaccgtgct aagtacaatg aagagccttc
    10381 aacatttgca gccttggctt atgattcagt tcaccttgta gcaaacgcag caaaaggtgc
    10441 taaaaattca ggtgaaatca aggataacct tgctaaaaca aaagattttg aaggtgtaac
    10501 tggtcaaaca agcttcgatg cagaccacaa cacagtcaaa actgcttaca tgatgaccat
    10561 gaacaatggt aaagttgaag tagcagaagt tgtaaaacca taatagaaaa atgttgaaat
    10621 agggaatgag cctttgactc actccctgtt tcgatattta atactcttcg aaaatctctt
    10681 caaact
//
LOCUS       DAVBOD010000069        10517 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 640-05
            SAMEA1012484-rid20186543.denovo.069, whole genome shotgun sequence.
ACCESSION   DAVBOD010000069 DAVBOD010000000
VERSION     DAVBOD010000069.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012484
            Sequence Read Archive: ERR059358
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10517)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10517)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979948.1
            Genome Coverage       :: 595x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:03:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,266
            CDSs (total)                      :: 2,219
            Genes (coding)                    :: 2,091
            CDSs (with protein)               :: 2,091
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 71 of 128
            Pseudo Genes (incomplete)         :: 50 of 128
            Pseudo Genes (internal stop)      :: 33 of 128
            Pseudo Genes (multiple problems)  :: 22 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10517
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012484-rid20186543.denovo.069"
                     /strain="NIG 640-05"
                     /db_xref="taxon:1313"
     gene            <1..183
                     /locus_tag="VQ862_001872"
     CDS             <1..183
                     /locus_tag="VQ862_001872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET3116169.1"
                     /translation="LTVEDKAYNHALSKERSKVENIFVKVKTFKMFSTTYRNHRKRFG
                     LRMNLIAGIINHELGF"
     gene            251..499
                     /locus_tag="VQ862_001873"
     CDS             251..499
                     /locus_tag="VQ862_001873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001858369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3116170.1"
                     /translation="MVSSSGSEFQSGWQEHQLIAEKVSKTLDKTFDKDVREIPTSQFY
                     QKFVDEMGRTYSGNLILQELITVNGAYKATYIGELSSN"
     gene            630..1802
                     /locus_tag="VQ862_001874"
     CDS             630..1802
                     /locus_tag="VQ862_001874"
                     /EC_number="2.3.3.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004181031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA synthase"
                     /protein_id="HET3116171.1"
                     /translation="MTIGIDKIGFATSQYVLKLQDLAEARGIDPEKLSKGLLLKELSI
                     APLTEDIVTLAASASDSILTEQERQEVDMVIVATESGIDQSKAAAVFVHGLLGIQPFA
                     RSFEIKEACYGATAALHYAKLHVENSPESKVLVIASDIAKYGIETPGEPTQGAGSVAM
                     LITQNPRMMAFNNDNVAQTRDIMDFWRPNYSTTPYVNGVYSTQQYLDSLKTTWLEYQK
                     RYQLTLDDFAAVCFHLPYPKLALKGLKKIMDKSLPQEKKDLLQKHFDQSILYSQKVGN
                     IYTGSLFLGLLSLLENTDSLKAGDKIALYSYGSGAVAEFFSGELVEGYEAYLDKDRLN
                     KLNQRTVLSVADYEKVFFEEVNLDETNSAQFAGYENQDFALVEILDHQRRYSKVEK"
     gene            1802..3076
                     /locus_tag="VQ862_001875"
     CDS             1802..3076
                     /locus_tag="VQ862_001875"
                     /EC_number="1.1.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000704367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA reductase,
                     degradative"
                     /protein_id="HET3116172.1"
                     /translation="MKISWNGFSKKSYQERLELLKAQALLSPERQASLEKDEQMSVTV
                     ADQLSENVVGTFSLPYSLVPEVLVNGQEYTVPYVTEEPSVVAAASYASKIIKRAGGFT
                     AQVHQRQMIGQVALYQVANPKLAQEKIASKKAELLELANQAYPSIVKRGGGARDLHVE
                     QIKGEPDFLVVYIHVDTQEAMGANMLNTMLEALKPVLEELSQGQSLMGILSNYATDSL
                     VTASCRIAFRYLSRQKDQGREIAEKIALASQFAQADPYRAATHNKGIFNGIDAILIAT
                     GNDWRAIEAGAHAFASRDGRYQGLSCWTLDLEREELVGEMTLPMPVATKGGSIGLNPR
                     VALSHDLLGNPSARELAQIIVSIGLAQNFAALKALVSTGIQQGHMKLQAKSLALLAGA
                     SESEVAPLVERLISDKTFNLETAQRYLENLRS"
     gene            complement(3111..4076)
                     /locus_tag="VQ862_001876"
     CDS             complement(3111..4076)
                     /locus_tag="VQ862_001876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002929307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HET3116173.1"
                     /translation="MVAKLTDVAKLAGVSPTTVSRVINKKGYLSEKTIQKVNEAMREL
                     SYKPNNLARSLQGKSAKLIGLIFPNISNVFYAELIDKLEHQLFKNGYKTIICNSEHDS
                     EKEREYIEMLEANQVDGIISGSHNLGIEDYNRVTAPIISFDRNLSPDIPVVSSDNYAG
                     GVLAAQTLVKTGAQSIIMITGNDNSNSPTGLRHAGFASVLPKAPIINVSSDFSPVRKE
                     MEIKNILTREKPDAIFASDDLTAILIIKIAQELGISVPKELKVIGYDGTYFIENYYPQ
                     LATIKQPLEEIACLTIDLLLQKIEGKEVATTGYFLPVTLLPGKSI"
     gene            complement(4057..5511)
                     /locus_tag="VQ862_001877"
     CDS             complement(4057..5511)
                     /locus_tag="VQ862_001877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 32 protein"
                     /protein_id="HET3116174.1"
                     /translation="MEWTTERRYRLYQDWTQEEIQHIKENMAQSPWHTHYHVEPKTGL
                     LNDPNGFSYFDGKWILFYQNFPFGAAHGLKSWAQLESDDLVHFKETGIKVLPDTPLDS
                     HGAYSGSAMQFGDNLFLFYTGNVRDENWIRHPYQIGALMDKEGKITKIDKILIDQPAD
                     STDHFRDPQIFNFKGQYYAVVGGQDLEKKGFVRLYKAVNNDYTNWQAVGDLDFANDRT
                     AYMMECPNLIFVEEQPVLLYCPQGLDKKVLDYDNIFPNMYKIGASFDPKNAKMVDVSQ
                     LQNMDYGFEAYATQAFNAPDGRALAVSWLGLPDVSYPSDCFDHQGTFSLVKELTIKDD
                     KLYQYPVAAIKDLRASEEAFSNRSQTKNTYELELNLEANSQSEIVLLADKEGKGLSIN
                     FDLVNGQVTVDRSQAGEQYAQEFGTTRSCPIENQATTATIFIDNSVFEIFINKGEKVF
                     SGRVFPHADQNGILIKSGNPTGTYYELDYGRKTN"
     gene            5887..7770
                     /locus_tag="VQ862_001878"
     CDS             5887..7770
                     /locus_tag="VQ862_001878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HET3116175.1"
                     /translation="MNNQEIAKKVIDALGGRENVNSVAHCATRLRVMVKDEEKINKEV
                     IENLEKVQGAFFNSGQYQIIFGTGTVNKMYDEVVVLGLPTSSKDDMKAEVAKQGNWFQ
                     RAIRTFGDVFVPIIPVIVATGLFMGVRGLFNALEMPLPGDFATYTQILTDTAFIILPG
                     LVVWSTFRVFGGNPAVGIVLGMMLVSGSLPNAWAVAQGGEVTAMNFFGFIPVVGLQGS
                     VLPAFIIGVVGAKFEKAVRKVVPDVIDLLVTPFVTLLVMSILGLFVIGPVFHVVENYI
                     LIATKAILSMPFGLGGFLIGGVHQLIVVSGVHHIFNLLEVQLLAADHANPFNAIITAA
                     MTAQGAATVAVGVKTKNPKLKTLAFPAALSAFLGITEPAIFGVNLRFRKPFFLSLIAG
                     AIGGGLASILGLAGTGNGITIIPGTMLYVGNGQLPQYLLMVAVSFALGFALTYMFGYE
                     DEVDATAAAKQAEVAEEKEEVAPAALQNETLVTPIVGDVVALADVNDPVFSSGAMGQG
                     IAVKPSQGVVYAPADAEVSIAFPTGHAFGLKTRNGAEVLIHVGIDTVSMNGDGFEAKV
                     AQGDKVKVGDVLGTFDSNKIATAGLDDTTMVIVTNTADYASVAPVATGSVAKGDAVIE
                     VKI"
     gene            7919..8806
                     /locus_tag="VQ862_001879"
     CDS             7919..8806
                     /locus_tag="VQ862_001879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000164317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HET3116176.1"
                     /translation="MTKLYGSLEAGGTKFVCAVGDENFNVVEKTQFPTTTPIETIDKT
                     IEFFSKFDNLAGLAVGSFGPIDIDKNSKTYGFITTTPKPNWANVDLLGALRRALNVPM
                     YFTTDVNSSAYGEVVARNNAGGRIENLVYYTIGTGIGAGVIQRGEFIGGVGHPEMGHY
                     YVARHPMDIEKEFKGVCPFHKGCLEGYAAGPSLEARTGVRGETIELNNPVWDVQAYYI
                     AQAAVNATVTFRPDVIVFGGGVMAQQHMLDRVREKFTSLLNGYLPVPDVRDYIVTPAV
                     AGNGSATLGNFVLAKEVSK"
     gene            complement(8849..9466)
                     /locus_tag="VQ862_001880"
     CDS             complement(8849..9466)
                     /locus_tag="VQ862_001880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000076166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HET3116177.1"
                     /translation="MSQDKQMKAVSPLLQRVINISSIVGGVGSLIFCIWAYQAGILQS
                     KETLSAFIQQAGIWGPPLFIFLQILQTVVPIIPGALTSVAGVFIYGHIIGTIYNYIGI
                     VIGCAIIFYLVRLYGAAFVQSVVSKRTYDKYIGWLDKGNRFDRFFIFMMIWPISPADF
                     LCMLAALTKMSFKRYMTIIILTKPFTLVVYTYGLTYIIDFFWQML"
     gene            complement(9881..10069)
                     /locus_tag="VQ862_001881"
                     /pseudo
     CDS             complement(9881..10069)
                     /locus_tag="VQ862_001881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155321.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
BASE COUNT         3059 a         2055 c         2337 g         3066 t
ORIGIN      
        1 ctaacagttg aagataaagc ctataaccat gcgctatcta aggagagaag caaggttgag
       61 aacatctttg tcaaagtaaa aacgtttaaa atgttttcaa caacctatcg aaatcatcgt
      121 aaacgcttcg gattacgaat gaatttgatt gctggcatta tcaatcatga actaggattc
      181 tagttttgca ggaagtctac tactttcctt attgtctgta aatctactga ccttgttgtt
      241 tatcccagtc atggtttcta gttcgggctc agagtttcaa agtggatggc aagagcatca
      301 attgattgct gagaaggtta gtaaaacact tgataagaca tttgataagg atgtcagaga
      361 aattccgacc agtcagtttt atcaaaaatt tgtagatgag atgggaagga cttactcagg
      421 aaatttgatc ctccaggagc tgataactgt gaatggagct tataaagcta cttatatcgg
      481 tgaactctct agcaactaat cattctttaa aatgatgacc aataagaggc ttgatttggt
      541 gaatcaagtc ttttttctct cttttactgc catttgtgat aaaatagtat agaacgattt
      601 tttacatgaa tgataaaaca gaggtaaata tgacaatcgg tattgataag attggttttg
      661 cgaccagtca atatgtcttg aaattacaag acttagcaga agcgagggga attgaccctg
      721 aaaaattaag taaaggactc ttactcaagg aattgagtat tgcgccccta actgaggaca
      781 tcgtgacctt ggcggccagt gctagtgact ctattttaac tgagcaagaa agacaagaag
      841 ttgacatggt cattgtggcg accgagtcag gaattgacca gagtaaggct gcggccgtct
      901 ttgtgcatgg cttgctgggc atccagccct ttgctcgtag tttcgagatt aaagaagcct
      961 gctatggggc gactgctgcc ctccattatg ccaaattgca tgtggaaaat tctccggagt
     1021 ccaaggtctt ggtcattgca agtgatattg ccaaatacgg tattgaaact ccgggagaac
     1081 ccactcaggg tgccggaagt gtggctatgt tgattacaca aaatccacgc atgatggcct
     1141 ttaataatga caatgtagct cagacccgtg acatcatgga tttctggcga ccaaattact
     1201 cgacaactcc ttatgtaaat ggtgtctatt ctacccaaca atacttggat agtttgaaaa
     1261 cgacttggct tgaatatcaa aaacgctacc agcttacttt ggatgatttt gcggctgttt
     1321 gtttccactt gccttatcct aaattagcgc taaaaggctt gaaaaaaatc atggataaga
     1381 gcctgcctca agagaaaaaa gacctcttac aaaagcattt tgaccagtct attctctaca
     1441 gtcaaaaggt ggggaatatc tacacaggtt cacttttcct tggacttttg tctctcttgg
     1501 aaaatacaga tagcttgaaa gctggggata aaatcgccct ttatagttac ggaagtggag
     1561 ctgtggctga gttcttcagt ggtgaattgg ttgaaggata tgaagcttat ttggataaag
     1621 accgcttgaa caagctcaac caacgaactg tcttatccgt tgcagactat gaaaaggtct
     1681 tttttgagga agtaaacttg gatgaaacaa actctgccca gtttgctggc tatgaaaatc
     1741 aagattttgc cttggttgaa attctcgacc accaacgccg ttatagcaag gttgaaaaat
     1801 aatgaagata agttggaatg gattttctaa aaaatcatac caagagcgcc tcgagctgtt
     1861 aaaagctcag gcgctcctta gtcctgagag acaagctagt ctggagaagg atgaacagat
     1921 gagcgtgact gtggcagacc agctgagtga gaatgtagtg ggaacttttt ctctgcctta
     1981 ttcactggtt ccggaggtac ttgtcaacgg tcaggaatac accgttccct atgtgacaga
     2041 agaaccctct gtggttgcgg cggccagcta tgccagcaaa atcatcaagc gtgcaggtgg
     2101 ttttactgca caagtccatc agcgacagat gattgggcag gtagcccttt atcaagttgc
     2161 taatcctaaa ctagcgcaag agaagattgc cagcaagaaa gcggagctct tggagcttgc
     2221 caatcaagcc tatccttcta tcgttaaacg tggaggtggg gcgcgtgatc tgcatgtcga
     2281 gcagataaaa ggcgaaccag actttctcgt tgtttatatt catgtcgata cccaggaagc
     2341 catgggtgcc aatatgctca acaccatgct ggaagccttg aaaccagtct tagaagaact
     2401 cagtcaggga cagagtctca tgggaatcct gtccaactac gcgaccgatt ctctggtgac
     2461 tgcaagctgt cgcatcgcct ttcgctactt gagccgccaa aaggatcaag gacgagagat
     2521 tgcggagaaa attgcgttgg ctagtcagtt tgcgcaggct gatccttacc gagctgctac
     2581 tcataataaa ggaattttta atggtattga tgcgattttg attgccactg gtaatgactg
     2641 gcgtgccatc gaagctgggg cccatgcctt tgccagtcga gatggacgct atcaaggtct
     2701 tagttgctgg acgctggacc ttgaaagaga agaattggtc ggtgagatga ccctgcccat
     2761 gcctgtagcg actaagggtg gctctatcgg cctcaaccca cgtgtagctc tcagtcatga
     2821 tctactagga aatccttctg ccagagaatt agcccagatt atcgtgtcca tcggtcttgc
     2881 ccaaaatttt gcagccctca aagccttggt aagtacgggc atccagcaag gccacatgaa
     2941 actacaggcc aaatccctag ctctcctagc tggggctagt gaatctgaag ttgctcccct
     3001 agtagagcgc ctcatctcag ataaaacctt taacctagag acagcccagc gctatctcga
     3061 aaatttaaga tcataaaaac tcagacgaat cggtctgagt tttcttgtgt ttaaatactt
     3121 tttcctggta atagtgtaac tggtaagaag taaccagttg tggcgacttc cttgccttca
     3181 atcttttgca agagaagatc aatagtgaga caagcaatct cttccaaagg ttgcttgata
     3241 gtagccaatt gagggtagta attttcgata aagtaggtcc catcatagcc gataaccttg
     3301 agctcttttg ggacagaaat gcccaattct tgagcgattt taatgatcag aatagctgtc
     3361 aaatcatccg aagcaaaaat ggcatctggt ttttcccggg tcaagatatt cttgatttcc
     3421 atttcttttc tgacgggaga aaagtcactg gaaacattga taataggagc ttttgggagt
     3481 acggatgcaa aaccagcgtg gcgcagtccg gttggcgaat tggaattgtc attccctgta
     3541 atcatgatga tagactgggc acctgtcttg accaaggttt gggcagcaag aaccccacca
     3601 gcatagttgt cagaggagac aacagggatg tctggcgata ggtttcggtc aaaggaaata
     3661 atcggcgctg tcacacgatt gtagtcttcg attcctaggt tgtgactacc agaaatgatg
     3721 ccgtctacct gattggcttc caacatttcg atgtattcgc gttccttctc agaatcatgt
     3781 tcactgttgc agatgatggt cttgtaacca tttttgaaga gttggtgttc caatttatca
     3841 atcaattctg catagaaaac attggaaata ttggggaaaa tcaagccgat taacttagct
     3901 gattttcctt gcagactacg agccaggttg ttgggtttat agcttaattc tctcatggct
     3961 tcattgactt tttggatggt tttctcagat agataccctt ttttattgat aacccgagaa
     4021 acggtagtag gactgacgcc tgcaagtttg gcgacatcag ttagttttgc gaccataatc
     4081 taattcatag taagttccag ttgggtttcc agatttgatc aggataccat tttggtccgc
     4141 atgtgggaag acacgaccag aaaatacttt ttctccttta ttgatgaaaa tttcaaagac
     4201 agagttatcg atgaagattg tagcagtagt agcctgattc tcgatagggc aagaacgagt
     4261 tgtcccaaat tcttgggcat actgttctcc agcctggcta cgatccactg tcacttgacc
     4321 gtttacaagg tcaaagttga ttgaaagtcc cttaccttct ttatcagcaa gtaagacaat
     4381 ctcgctctgg ctattagctt ccaagttgag ttcaagttcg taagtgttct tggtttggga
     4441 acggtttgag aaggcttctt cagaagcacg aaggtcctta atagcagcga ctggatactg
     4501 gtagagcttg tcgtctttga tagtgagttc cttgaccaaa gagaaggttc cttggtgatc
     4561 aaaacagtca gatgggtaag aaacatctgg caaaccaagc cagctaactg ctagagcacg
     4621 cccatcagga gcgttgaagg cttgagttgc ataggcttcg aaaccgtaat ccatgttttg
     4681 aagttgagac acatctacca ttttggcatt tttagggtca aaggaagccc caatcttata
     4741 catatttgga aagatattat cgtagtctag aactttctta tccaatcctt gtggacagta
     4801 gagaaggaca ggctgttcct ctacaaagat cagattagga cattccatca tgtaggcagt
     4861 acggtcgtta gcaaagtcaa ggtcgccaac tgcttgccag tttgtgtagt cgttattgac
     4921 agccttgtag agacggacga agcctttttt ctccaagtcc tgtccaccga cgacagcata
     4981 gtattgacct ttaaagttaa aaatttgtgg atcgcggaag tggtcagtag agtctgctgg
     5041 ctggtcaatc aagatcttgt caatctttgt aatcttaccc tccttgtcca tcaaagcacc
     5101 gatctggtat gggtgacgga tccagttttc atcgcgaaca tttcctgtat aaaataggaa
     5161 taagttatcg ccaaattgca tggcagaacc agagtaggca ccgtggctat ctaatggagt
     5221 atctggtaaa actttgattc cagtttcttt aaagtgaacc aaatcatcac tttctagctg
     5281 tgcccaagat ttcaaaccgt gggctgcacc aaaaggaaaa ttctggtaaa agaggatcca
     5341 cttgccatca aagtaagaaa agccatttgg gtcgttgaga agtcctgttt ttggctcaac
     5401 atggtaatga gtatgccatg gagattgtgc catattttcc tttatatgtt gaatttcttc
     5461 ttgcgtccaa tcttgataaa gtctgtaacg acgctcagtt gtccattcca ttcattcctc
     5521 caaaaatctt atcactttta atagtaactg ttttcgataa aaaatgcaag ccttttatgt
     5581 taaaaaagag gaaaaactgt caaacgatta tcataaaata aatacaggaa atcaatcaaa
     5641 tttttacgaa aatgtgaaag ataatgaaat aaaatacttt ttaaccaagg tttcaaactt
     5701 atttttcaag gaattcctga tgaaacagtc aaaaacaatc aatctaaagc ttgcccacta
     5761 agtggataga atatttttat gcaaaacgct tgacatattt ttaaaacatg ataaaataat
     5821 agtcgtaagg gcgaataaaa tcgctttcaa acaagaacaa aatgttatat aaggagattt
     5881 ttgcaaatga acaatcagga aattgcaaaa aaagtcatcg atgccttggg cggacgtgaa
     5941 aatgtcaata gtgttgccca ctgtgcgact cgtctacgtg tcatggtcaa agatgaagag
     6001 aaaatcaata aagaagtgat tgagaacttg gaaaaagttc aaggtgcttt ctttaactca
     6061 gggcaatacc aaattatctt tggtacaggt acagttaaca aaatgtacga tgaagttgtt
     6121 gtacttggat taccaacatc atctaaggat gacatgaaag cagaagttgc taaacaaggg
     6181 aactggttcc aacgtgctat ccgtactttt ggtgatgttt tcgttccaat catcccagtt
     6241 atcgtagcga caggtctctt catgggtgtg cgtggtcttt tcaacgctct tgaaatgcca
     6301 cttccaggtg actttgcaac ttacacacaa atcttgacag atacagcctt catcatcttg
     6361 ccaggtttgg ttgtgtggtc aaccttccgt gtatttggtg gaaatcctgc cgttggtatc
     6421 gttcttggta tgatgcttgt ctctggctca cttccaaacg cttgggcagt tgctcaaggt
     6481 ggtgaagtaa cagcgatgaa cttttttggt ttcatccctg ttgttggttt gcaaggttcc
     6541 gttcttccag ccttcatcat cggggttgtc ggagctaaat ttgaaaaagc tgtccgcaag
     6601 gttgttccag atgtcattga cctcttggta acaccattcg tgacactttt ggtcatgtct
     6661 atccttggac tctttgtcat tggaccagtt ttccacgttg ttgaaaacta catccttatt
     6721 gctacaaaag cgattcttag catgccattt ggtcttggtg gtttcttgat tggtggggtt
     6781 caccaattga tcgtcgtgtc aggtgtgcac cacatcttca acttgcttga agtgcaatta
     6841 cttgctgctg accatgctaa cccattcaac gctatcatca cagctgctat gacagctcaa
     6901 ggtgctgcta ctgttgcggt tggtgttaaa acaaaaaatc caaaactgaa aacacttgct
     6961 ttcccggctg ctctttctgc cttcctaggt attacagagc ctgctatctt cggggtgaac
     7021 ttgcgcttcc gtaaaccatt cttcctttca ttgattgctg gtgcaatcgg tggtggattg
     7081 gcttctatcc ttggacttgc tggtactggt aatggtatca ccatcatccc tggtacaatg
     7141 ctttatgttg gtaacggaca acttccacaa taccttctta tggtagctgt atcatttgcc
     7201 cttggttttg ctcttactta catgtttggt tacgaagatg aagtagacgc aactgcagct
     7261 gcaaaacaag ctgaagtggc tgaagaaaaa gaagaagttg cgccagcagc tcttcaaaat
     7321 gaaacacttg taactcctat cgtcggtgat gttgtcgctc ttgctgatgt caatgaccca
     7381 gtcttctcaa gtggagctat gggacaaggt atcgctgtga aaccaagcca aggcgtggtc
     7441 tatgcaccag ctgatgctga agtttcaatt gcctttccaa cagggcacgc ttttggtttg
     7501 aaaacaagaa atggtgctga agttttgatt catgttggta ttgacactgt atctatgaac
     7561 ggtgacggtt ttgaagcaaa agttgctcaa ggtgataagg tgaaagttgg cgatgttctt
     7621 ggaacatttg actcaaataa aatcgctaca gctggacttg atgatacaac aatggttatc
     7681 gttacaaata cagctgacta cgcttcagta gctccagtcg caacaggttc agttgcgaag
     7741 ggggatgctg tgatcgaagt gaaaatctaa tcaatcctct ctaatgtgaa aacgaacaaa
     7801 tgacatgttt gttcgttttt attagatagt aagatttaca gaggaaaatc taaaaaatag
     7861 agacatttag actttcgaag tatgctataa taaagaaaat aaaaacaaga ggtttatcat
     7921 gacaaaatta tatggaagct tggaagctgg cggtacaaag tttgtctgtg ctgttggtga
     7981 tgaaaacttt aacgttgtag aaaaaacaca atttccaaca acaactccaa tcgaaacaat
     8041 cgataaaacc attgagttct tctcaaaatt cgataacctt gctggtcttg cagttggttc
     8101 atttgggccg attgatattg acaaaaactc aaaaacttat ggctttatca cgacgactcc
     8161 aaaaccaaac tgggcaaatg tggacttgct tggtgccctt cgtcgcgccc taaacgtgcc
     8221 aatgtacttc acaacagacg taaacagctc tgcttacggt gaagtggttg cccgtaacaa
     8281 tgctggtggt cgtatcgaaa acttggttta ctacacaatc ggtacaggta tcggtgcagg
     8341 cgtcatccaa cgtggtgagt ttatcggtgg tgtgggtcac cctgaaatgg gtcattatta
     8401 tgttgctaga cacccaatgg atattgaaaa agagtttaag ggtgtttgtc ctttccataa
     8461 gggatgtctg gaaggctatg cagctggtcc aagtttggaa gctcgtacag gtgtacgtgg
     8521 ggaaactatt gaactcaaca accctgtttg ggatgttcaa gcctactata tcgctcaagc
     8581 tgcggttaat gcgacagtga ctttccgccc agacgtgatt gtctttggtg gaggggtcat
     8641 ggctcaacaa catatgctgg accgtgtccg tgagaaattt acatctcttc ttaatggtta
     8701 cctaccagta ccagatgtgc gtgactatat cgtgacgcca gcagtcgcag gaaatggttc
     8761 tgccacactt gggaactttg ttcttgcaaa agaagtttca aaataaagca caaaatccgc
     8821 ttgggaaacc aaacggattt tttacgtgtc aaagcatttg ccagaaaaag tcaataatat
     8881 aggtcagacc gtaggtataa accacgaggg taaagggttt ggtcagaatg atgatggtca
     8941 tgtagcgctt gaaactcatc ttggtcaggg cagccagcat acagagaaag tcagctgggc
     9001 taatgggcca aatcatcata aaaataaaga agcggtcaaa acgattgccc ttatctagcc
     9061 agccgatgta cttgtcgtag gtgcgcttgc tgacgacaga ctggacaaag gcagctccgt
     9121 ataggcgcac tagataaaag ataatggcac agccaatcac gatgccgata tagttgtaga
     9181 tagtcccgat gatgtgcccg tagataaaga ccccagccac cgaggtcaag gcccctggaa
     9241 tgatagggac gacagtctgt aaaatctgta aaaagataaa gagaggtgga ccccagatgc
     9301 ctgcctgctg gataaaggca gagagggttt ccttggattg taaaatccca gcctgataag
     9361 cccaaataca gaaaatcaaa ctcccaaccc caccgacaat cgatgagata ttgataactc
     9421 gctgcaaaag gggagaaaca gctttcattt gtttatcctg tgacatgtaa actcctcata
     9481 gatagtatat ttctactata ccatattttg gaggagaaag ggggaatgag tcttttttga
     9541 taaggaatag aaagtaaata gcccttcgag acttagaata ggtctgtcaa ctaaaggtta
     9601 tatgcattct aggtttcaaa taatcgcaat tccataaatt taaaagcatt ctaagtttcg
     9661 aatagcttat ctgagataat tttgaggcat tcgcgctttc gaatagtcat tttccctaaa
     9721 gtttagatgt attctgaagc tagaaagact aaaatctaaa agtagtaaga gtctctctct
     9781 gatggacgta atttatggct agtatgaatc ctttgaattg ttagttaatt ttaatattaa
     9841 tcagttctga aataattact aaatatagtt agatggtgaa ttaattattg ctaaatttca
     9901 agttcaagtt agtcatccag aagtcttctc tgggggactt gtagttcaag cattttttag
     9961 gatagttgtt aatccacttt tcgatgaatg cgacttcctt tgtagtcgtt ttcttagttt
    10021 cctgaggtaa ctatctatga atgagcctgt tgtgattttc attagatcct ataggggtgt
    10081 gcataataga tatagcagat tgaaactaga atagtataca tctacttcta aaacattgtt
    10141 agaaatcaat ttgactgtcc tgatcaattt gtcctgttct tatttcattt tactatataa
    10201 tccttagaaa acatatggga caagcggttg aattctgttc cgtccattag tagataaagg
    10261 attactcctt cttgaaatga cagatgaact tgtttcttat aaaaatgttg tctgaaacta
    10321 ttagcctttt tccagaagtt ttagaggaag aaaactttac gaggaaaaag gagttactca
    10381 aataacaatt caggattaaa aatagacagt tgaggagcgg aaggtataaa ttaagtttgc
    10441 tgctgtataa tggatttatc actaatactc ttcgaaaatc tcttcaaacc acgtcagctt
    10501 cgccttgccg tagatat
//
LOCUS       DAVBOD010000070        10512 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 640-05
            SAMEA1012484-rid20186543.denovo.070, whole genome shotgun sequence.
ACCESSION   DAVBOD010000070 DAVBOD010000000
VERSION     DAVBOD010000070.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012484
            Sequence Read Archive: ERR059358
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10512)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10512)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979948.1
            Genome Coverage       :: 595x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:03:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,266
            CDSs (total)                      :: 2,219
            Genes (coding)                    :: 2,091
            CDSs (with protein)               :: 2,091
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 71 of 128
            Pseudo Genes (incomplete)         :: 50 of 128
            Pseudo Genes (internal stop)      :: 33 of 128
            Pseudo Genes (multiple problems)  :: 22 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10512
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012484-rid20186543.denovo.070"
                     /strain="NIG 640-05"
                     /db_xref="taxon:1313"
     gene            171..383
                     /locus_tag="VQ862_001882"
                     /pseudo
     CDS             171..383
                     /locus_tag="VQ862_001882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            283..729
                     /locus_tag="VQ862_001883"
     CDS             283..729
                     /locus_tag="VQ862_001883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HET3116178.1"
                     /translation="MRKHGLISKSTSKGYYQVAIPFMRLFCLVLVSIDYINCLSETTD
                     KNWHKSDRIFVTNTGKPVHSSILSKSLQRANERLKKPIPKHLSPHIFRHTTISILSEN
                     KIPLKTITDRVGHSDSEVTTSIYTHVTKNMKDEAINVLDKVMKKIF"
     gene            complement(867..2171)
                     /gene="eno"
                     /locus_tag="VQ862_001884"
     CDS             complement(867..2171)
                     /gene="eno"
                     /locus_tag="VQ862_001884"
                     /EC_number="4.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopyruvate hydratase"
                     /protein_id="HET3116179.1"
                     /translation="MSIITDVYAREVLDSRGNPTLEVEVYTESGAFGRGMVPSGASTG
                     EHEAVELRDGDKSRYGGLGTQKAVDNVNNIIAEAIIGYDVRDQQAIDRAMIALDGTPN
                     KGKLGANAILGVSIAVARAAADYLEIPLYSYLGGFNTKVLPTPMMNIINGGSHSDAPI
                     AFQEFMILPVGAPTFKEALRYGAEIFHALKKILKSRGLETAVGDEGGFAPRFEGTEDG
                     VETILAAIEAAGYVPGKDVFIGFDCASSEFYDKERKVYDYTKFEGEGAAVRTSAEQID
                     YLEELVNKYPIITIEDGMDENDWDGWKALTERLGKKVQLVGDDFFVTNTDYLARGIQE
                     GAANSILIKVNQIGTLTETFEAIEMAKEAGYTAVVSHRSGETEDSTIADIAVATNAGQ
                     IKTGSLSRTDRIAKYNQLLRIEDQLGEVAEYRGLKSFYNLKK"
     gene            2335..2781
                     /locus_tag="VQ862_001885"
     CDS             2335..2781
                     /locus_tag="VQ862_001885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000131081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YueI family protein"
                     /protein_id="HET3116180.1"
                     /translation="MTDLSKQLLEKAHGGLKINPDEQRRYLGTFEERVLGYVDIDTAN
                     SPQLEKGFLFILENLQEKAEPLFVKISPTIEFDKQVFYLKEAKETDSQATIVSEEHIT
                     SPLGLVIHSNAPVQVEEKDLRLAFPKLWEVKKEEPAKTSLWKKWFS"
     gene            complement(2778..3893)
                     /locus_tag="VQ862_001886"
     CDS             complement(2778..3893)
                     /locus_tag="VQ862_001886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000706318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HET3116181.1"
                     /translation="MKIVIAPDSFKESLTAQQVAEAIKRGFQQSIADVECLLCPVGDG
                     GEGTVDAIRHSLDLKEKWIQVTDPSGQKEAMRYFQKGELALFEVADLVGLGKIPLEKR
                     NPLQIQTCGIGELILHLISKGIKDIYIGVGGTASNDGGLGIAAGLGYQFYDRDGNVLP
                     ASDQSLLNLASVSTENCYKIPEGVQIHILADVVSPLCGHQGATYTFGNQKGLHPTMFA
                     VVDQAIQDFYEKFSPATLEIKGAGAGGGLAGGLCAFAQASIVSGIDTCLDLINFDKKV
                     SDADLVVVGEGRLDSQSFAGKAPIGVAKRTPVGVPVIAICGSLAEDLPPLPFENIQAV
                     FSILEKSEPLEDSLKNASLYLERTAANIGHLLNMCKI"
     gene            complement(4007..4231)
                     /locus_tag="VQ862_001887"
     CDS             complement(4007..4231)
                     /locus_tag="VQ862_001887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HET3116182.1"
                     /translation="MERLAKSLGIAYFTANQLEVKEGLLTGKLVGQIISPQVKKETLE
                     KWRKKLKLSKERTVAIGDGVNNLLMLKSAE"
     gene            complement(4176..4547)
                     /locus_tag="VQ862_001888"
     CDS             complement(4176..4547)
                     /locus_tag="VQ862_001888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IB family phosphatase"
                     /protein_id="HET3116183.1"
                     /translation="MSQVKGLCVLDVDGTLILEEVIDLLGREAGHEAEISQITSRAMR
                     GELVFESSLRKRVSLLEGLPILVFDNVFNSIHLSLNVPEFISILQKNGILVGLVSGGF
                     TPIVGEISKIPWYCLFHCQPA"
     gene            complement(4606..6039)
                     /gene="glgA"
                     /locus_tag="VQ862_001889"
     CDS             complement(4606..6039)
                     /gene="glgA"
                     /locus_tag="VQ862_001889"
                     /EC_number="2.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000697278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen synthase GlgA"
                     /protein_id="HET3116184.1"
                     /translation="MKILFVAAEGAPFSKTGGLGDVIGALPKSLVKAGHEVAVILPYY
                     DMVEAKFGSQIEDVLHFEVSVGWRRQYCGIKKTVLNGVTFYFIDNQYYFFRGHVYGDF
                     DDGERFAFFQLAAIEAMERIDFIPDLLHVHDYHTAMIPFLLKEKYRWIQAYEDIETVL
                     TIHNLEFQGQFSEGMLGDLFGVGFERYADGTLRWNNCLNWMKAGILYANRVSTVSPSY
                     AHEIMTSQFGCNLDQILKMESGKVSGIVNGIDADLYNPQTDALLDYHFNQEDLSGKAK
                     NKAKLQERVGLPVRADVPLVGIVSRLTRQKGFDVVVESLHHILQEDVQIVLLGTGDPA
                     FEGAFSWFAQIYPDKLSTNITFDVKLAQEIYAACDLFLMPSRFEPCGLSQMMAMRYGT
                     LPLVHEVGGLRDTVRAFNPIEGSGTGFSFDNLSPYWLNWTFQTALDLYRNHPDIWRNL
                     QKQAMESDFSWDTACKSYLDLYHSLVN"
     gene            complement(6036..7175)
                     /gene="glgD"
                     /locus_tag="VQ862_001890"
     CDS             complement(6036..7175)
                     /gene="glgD"
                     /locus_tag="VQ862_001890"
                     /EC_number="2.7.7.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate adenylyltransferase subunit
                     GlgD"
                     /protein_id="HET3116185.1"
                     /translation="MKIDKYSAILGNTVGFHNMSTLTDHRPVASLPFGGKYRLIDFPL
                     SSLANAGVRSVFGIFQQDNISSVFDHIRSGREWGLSTLLSHYYLGIYNTRVESSTVGK
                     EYYQQLLTYLKRSGSNQTVALNCDVLINIDLNQVFHLHSTTKEPITVVYKKLAKKDIS
                     EVNAILDVDETDHVLSHKLFDSKSTAETFNMSTDIFVVDTPWLIEHLEEEAKKEHPEK
                     LRYVLRDLAVKEGAFAYEYTGYLANIHSVKSYYQANIDMLESQKFYSLFSPNQKIYTK
                     VKNEEPTYYANTSKVSTSQFASGSIIEGQVANSVLSRNIHVHKDSLVKDSLLFPRVVI
                     GEGAQVEYAILDKGVEVEPGVVIRGTAEHPVVVKKGAKVTEDIHS"
     gene            complement(7165..8307)
                     /locus_tag="VQ862_001891"
     CDS             complement(7165..8307)
                     /locus_tag="VQ862_001891"
                     /EC_number="2.7.7.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000787267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate adenylyltransferase"
                     /protein_id="HET3116186.1"
                     /translation="MKNEMLALILAGGQGTRLGKLTQSIAKPAVQFGGRYRIIDFALS
                     NCANSGIHNVGVVTQYQPLALNNHIGNGSSWGLDGINSGVSILQPYSASEGNRWFEGT
                     SHAIYQNIDYIDSVNPEYVLILSGDHIYKMDYDDMLQSHKDNNASLTVAVLDVPLKEA
                     SRFGIMNTDANNRIVEFEEKPAQPKSTKASMGIYIFDWQRLRNMLVAAEKSKVGMSDF
                     GKNVIPNYLESGESVYAYEFSGYWKDVGTIESLWEANMEYISPENALDSRNRQWKIYS
                     RNLISPPNFLGANAHVEDSLVVDGCFVDGTVKHSILSTGAQVREGAEVLDSVIMSGAI
                     IGQGAKIKRAIIGEGAIISDGVEIDGTDEVQVVGYNEVVGVATDED"
     gene            complement(8297..10225)
                     /gene="glgB"
                     /locus_tag="VQ862_001892"
     CDS             complement(8297..10225)
                     /gene="glgB"
                     /locus_tag="VQ862_001892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1,4-alpha-glucan branching protein GlgB"
                     /protein_id="HET3116187.1"
                     /translation="MDNREALKTFMTGENFYLQHYLGAHREELNGEHGYTFRVWAPNA
                     QAVHLVGDFTNWIENQIPMVRNDFGVWEVFTNMAQEGHIYKYHVTRQNGHQLMKIDPF
                     AVRYEARPGTGAILTELPEKKWKDGLWLARRKRWGFEERPVNIYEVHAGSWKRNSDGS
                     PYSFAQLKDELIPYLVEMNYTHIEFMPLMSHPLGLSWGYQLMGYFALEHAYGRPEEFQ
                     DFVEECHTHNIGVIVDWVPGHFTINDDALAYYDGTPTFEYQDHNKAHNHGWGALNFDL
                     GKNEVQSFLISCIKHWIDVYHLDGIRVDAVSNMLYLDYDNAPWTPNKDGGNLNYEGYY
                     FLQRLNEVIKLEYPDVMMIAEESSSATKITGMKEIGSLGFDYKWNMGWMNDILRFYEE
                     DPIYRKYDFNLVTFSFMYVFKENYLLPFSHDEVVHGKKSMMHKMWGDRYNQFAGLRNL
                     YTYQICHPGKKLLFMGSEYGQFLEWKSEEQLEWSNLEDPMNAKMKYFASQLNQFYKDH
                     RCLWEIDTSYDGIEIIDADNRDQSVLSFIRKGKKGEMLVCIFNMVPVERKDFTIGLPV
                     AGIYEEVWNTELEEWGGVWKEHNQTVQTQEGLWKDYEQTLTFTLPAMGASVWKIKRRL
                     KSTKTVTNKNQKGVENEK"
BASE COUNT         3202 a         2301 c         1850 g         3159 t
ORIGIN      
        1 gagcgacttt tttgaagctt ggtttcagaa atttctctta ccaacattaa ccgcaccatt
       61 ggttattata ttaaaacgaa gtaagaatag gacaaatcga tcaggacagt aaaatctaat
      121 tctaacaatg ttttagaagt agaggtgtac tattctagtt tcaatctact atattaatgg
      181 acaatgcaag attccataga atggggaagc tagaactctt gtgtgaagag tttgggcata
      241 aacttttacc tcttcctccc tactcgcctg agtacaatct tattgagaaa acatgggctc
      301 atatcaaaaa gcacctcaaa agggtattac caagttgcaa taccttttat gaggctcttt
      361 tgtcttgttc ttgtttcaat tgactatata aattgtctaa gcgaaacaac cgataagaat
      421 tggcacaaaa gcgaccgtat ttttgttacc aatacaggaa aaccagttca tagttctatc
      481 ttgagcaagt ctctccagcg agcaaacgaa cgccttaaaa aaccaattcc caaacatctg
      541 tcccctcaca tcttcagaca caccactatt agcatcttat cagaaaataa aattccttta
      601 aaaacaatca cggacagggt tggtcattcc gactctgaag tcactacttc catctacacc
      661 cacgtcacaa agaacatgaa agatgaagca atcaatgtac tggataaagt tatgaaaaag
      721 attttttaaa aagttttgtc ccttttttgt cctctaaata caaaaatagc ccttcggata
      781 aaatccgagg ggctagaaac gttgttaaat caacggccga acttttgaat ttcatggttc
      841 gggataaaat agttcactga actattttat tttttaaggt tgtagaatga tttcaatcca
      901 cgatattcag ctacttcacc aagttggtct tcgatacgaa gcaattggtt gtatttagcg
      961 atgcggtctg tacgtgaaag tgaaccagtc ttgatttgtc ctgcgttagt tgcaactgca
     1021 atatcagcga ttgttgaatc ttcagtttca cctgaacggt gtgatacaac agcagtgtaa
     1081 ccagcttctt tagccatttc gatagcttca aaagtttcag taagagtacc gatttggtta
     1141 actttgataa ggattgagtt agcagcacct tcttggatac cacgtgcaag gtagtcagtg
     1201 tttgttacga agaagtcgtc accaacaagt tgtactttct taccaagacg ttcagtaaga
     1261 gctttccaac catcccagtc gttttcatcc ataccatctt caatagtgat gattgggtat
     1321 ttgttaacca attcttcaag gtagtcgatt tgttctgcag atgtacgaac agcagcacct
     1381 tcaccttcaa atttagtgta gtcgtaaact ttacgttctt tatcgtagaa ttctgatgaa
     1441 gcacagtcaa atccgataaa tacgtcttta cctggtacat atccagcagc ttcaatcgca
     1501 gcaaggatag tttcaacacc atcttcagtt ccttcgaaac gaggagcgaa tccaccttcg
     1561 tcacctacgg cagtttccaa accacgtgat ttaaggattt tcttaagagc gtggaagatt
     1621 tcagcaccgt aacgaagggc ttctttaaat gttggcgcac caactggcaa gatcatgaac
     1681 tcttggaaag cgattggagc gtcagagtga gaaccaccgt tgatgatgtt catcattgga
     1741 gttggaagaa ctttagtgtt gaatccacca aggtagctgt aaagtgggat ttcaaggtag
     1801 tcagcagcag cacgagctac agcgatagac acaccgagga ttgcattcgc acccaattta
     1861 cctttgttag gagtaccgtc aagtgcgatc atagcacggt caatagcttg ttgatcacgt
     1921 acatcgtagc caatgatagc ttcagcaatg atgttgttta cgttgtcaac agctttttgt
     1981 gtaccaagac caccgtaacg agatttgtca ccgtcgcgaa gttcaactgc ttcgtgttca
     2041 ccagtagaag ctcctgatgg aaccatacca cgtccgaaag cacctgattc agtgtaaact
     2101 tctacttcaa gtgttgggtt accgcgtgag tctaggactt cgcgagcgta aacatcagta
     2161 ataattgaca ttttttactc tccttatgag ttaaattttt tacacctcta taatacctta
     2221 aaacccctcc tttttcaaga aaaaacgtta tctttgtgca acttttcctt aactttataa
     2281 agtaatcgct ttcttttgtc tgttttattc taacttttat gatatactgt tttcatgaca
     2341 gatttatcaa aacaattact tgaaaaagct catggtgggt taaaaataaa tccggatgag
     2401 caaagacgct atcttggtac ttttgaggaa agagttcttg gatatgtaga tattgacaca
     2461 gcaaatagcc ctcagttaga aaaaggcttt ttatttattt tagaaaacct tcaggaaaaa
     2521 gcagagccac tatttgtgaa gatttcacca actatcgaat ttgataagca agttttctac
     2581 ttaaaagaag caaaagaaac tgatagtcaa gccaccatag tatctgaaga gcatattact
     2641 tctcctttgg gcctggttat tcatagcaat gcaccagttc aagtagaaga aaaagacctt
     2701 cgacttgctt ttccaaaact ttgggaagtt aaaaaggaag aaccagccaa aacatcctta
     2761 tggaagaaat ggtttagcta aatcttgcac atatttaata agtgcccaat attggcagcc
     2821 gtgcgctcca gatagagact ggcatttttc aaactatctt ctaaaggttc acttttctcc
     2881 aaaatagaaa agacagcttg gatattttca aatggtaggg gaggtaaatc ttcagcaaga
     2941 ctaccgcaaa tagcaataac aggaactcca acaggggttc tttttgcaac acctataggc
     3001 gctttcccag caaagctttg actatcaagt cttccttctc caacaacaac caagtcagca
     3061 tctgaaactt tcttatcaaa gttgattaag tccaagcagg tatcaattcc agacacgata
     3121 cttgcctgag caaaggcaca caaaccacca gcaaggcctc cacctgctcc tgctccttta
     3181 atttctaatg ttgcaggtga gaatttttca taaaaatctt ggatcgcctg atctacgact
     3241 gcaaacatag tcggatgtag acctttttga ttgccaaaag tgtaagtcgc accttgatga
     3301 ccacataagg gactcacgac atctgctaga atatgaattt gaacaccttc aggaatttta
     3361 tagcaatttt ctgttgaaac agaagctaag tttaataagg attgatcgga agcaggcaag
     3421 acatttccat ccctatcata aaattgataa cctaaaccag cagcaatccc cagtcctcca
     3481 tcattactgg ccgtgccacc aacaccgata taaatatctt taatcccttt agaaatgaga
     3541 tggagaatca actctccaat accacaagtt tggatttgaa gtggatttcg tttctctagc
     3601 ggaatttttc caagaccaac caagtcagct acttcaaata gtgccagttc ccctttttga
     3661 aaatagcgca tggcttcttt ttgtccagaa gggtctgtca cttggatcca tttttctttt
     3721 aggtcaagag aatgtcggat agcatctaca gtaccttctc ccccatcacc aacagggcag
     3781 aggagacatt ctacatctgc tatcgattgt tggaagcctc tttttattgc ttcagctacc
     3841 tgttgagctg tcaagctttc cttaaacgaa tccggtgcaa ttacaatctt catattttcc
     3901 ctcattctaa acagtcaatc aaaggaagaa cttctaaaaa atccctcttg tcaacatgat
     3961 gtggtatttc ttttttgagc atttctttgg aacaaaaggc gattcctcac tccgccgact
     4021 tcaacattaa tagattattg accccatcac cgattgccac cgttctttct ttagaaagtt
     4081 ttagtttctt tctccatttt tccagagttt cttttttgac ctggggactt ataatttgtc
     4141 caactaattt tcctgttaaa agaccttctt tgacttcaag ctggttggca gtgaaatagg
     4201 caataccaag ggattttgct aatctctcca actattggtg taaatccacc agacaccaga
     4261 ccaactagga tgccattctt ttggagaata gagatgaact ctgggacatt tagcgataga
     4321 tgaattgagt tgaagacgtt atcaaagacc aaaataggaa gaccttccaa caaggacact
     4381 ctttttctta aactgctttc aaagaccaac tctcctcgca ttgctcgact tgtaatctgc
     4441 gaaatttccg cctcatgacc tgcctctctc cctaaaagat caatcacttc ttctaggatt
     4501 aaggttccat ctacatccaa aacacacaag ccttttactt gagacatcag ttctcctctc
     4561 taaacagcct aaaaatcgta tgaagtcatc atacgatttt atctattaat taactaaact
     4621 atggtacaag tcaaggtatg acttgcaggc tgtatcccat gagaagtcac tctccatagc
     4681 ttgtttttgt aggtttctcc aaatgtctgg atggtttcta tacaagtcca atgctgtttg
     4741 gaaagtccaa tttaaccaat aaggagatag attgtcaaag ctaaagccag taccgcttcc
     4801 ttcgattgga ttgaaagcgc gaactgtatc tcgcaagcct ccaacttcat ggaccaatgg
     4861 caaggttcca taacgcatag ccatcatttg agacaagcca cacggttcaa aacgacttgg
     4921 catgaggaag aggtcacaag cagcgtagat ttcctgagca agtttgacat caaaagtgat
     4981 atttgttgat agcttgtctg ggtaaatctg agcaaaccat gagaaagctc cttcaaaggc
     5041 tggatcgcca gttcccaaaa gaacaatctg aacatcttct tgcaagatat ggtgaagact
     5101 ttcgaccacc acatcaaaac ctttttgacg tgtcaaacga gaaacaattc ccaccagtgg
     5161 aacgtctgct ctaacaggca agccaactct ttcttgcaat tttgccttat ttttggcttt
     5221 cccagacaaa tcttcctgat tgaaatgata gtctaaaaga gcatccgtct gaggattata
     5281 aagatcagca tcaatcccat tcacgatacc agatacttta ccagactcca ttttaagaat
     5341 ctgatccaaa ttacatccaa actgactagt cataatttca tgagcatagc taggtgaaac
     5401 agttgaaaca cggttcgcat agagaatacc tgccttcatc cagttcagac agttgttcca
     5461 tcgaagggtg ccatcagcgt aacgttcaaa gccaactcca aacaaatcac ccaacattcc
     5521 ttctgaaaat tgtccttgga attctaaatt atgaatggtt aaaactgttt caatgtcctc
     5581 ataggcttga atccaacggt atttttcctt caacaagaaa ggaatcatag ctgtatggta
     5641 gtcatgaaca tggagaagat caggaataaa gtcaatcctt tccatagcct caatggcagc
     5701 cagttggaaa aaggcaaagc gttctccgtc atcaaaatca ccgtaaacat gaccacggaa
     5761 gaaataatat tgattgtcaa taaagtagaa ggttacacca tttaatactg ttttcttaat
     5821 tccacaatac tgtctgcgcc aaccaacgct cacctcaaaa tgaagcacat cttcaatctg
     5881 acttccaaat ttagcctcta ccatatcata gtagggtaaa atcactgcaa cttcgtgccc
     5941 agcttttacc agtgattttg gaagagcgcc aatgacgtct cccaaaccac ctgtttttga
     6001 aaagggtgca ccctctgctg ctacaaataa aattttcatg aatgaatatc ctctgttact
     6061 ttagcacctt tcttaaccac aactggatgt tctgcagttc ctcgaatcac aacaccaggc
     6121 tcaacttcaa cccctttgtc caagatagca tattcgacct gagccccttc tccaataaca
     6181 acacgaggga agagcaggct atctttaacc aagctatcct tatggacatg aatattacgt
     6241 gatagaacag aattagctac ttgaccttca ataatactac cagaggcaaa ctgagaagtg
     6301 cttaccttag atgtattagc atagtaagtt ggctcttcgt ttttgacctt tgtataaatc
     6361 ttttggtttg gtgagaaaag agaatagaat ttttgtgatt caagcatatc gatattcgct
     6421 tgataataag atttaacaga gtgaatattg gctagatagc ccgtgtactc gtaggcgaaa
     6481 gctccctctt ttacagccaa atcccgtaaa acatagcgca atttctctgg atgttctttt
     6541 ttagcttctt cttccaagtg ttcaatcaac caaggtgtat caacgacaaa gatatctgta
     6601 gacatattga acgtttcagc tgttgacttg ctatcaaaga gtttatgaga aagaacatgg
     6661 tctgtttcat ctacatccaa gattgcattt acttctgaaa tatctttctt agctagtttt
     6721 ttataaacta cagtgatagg ctcttttgtt gtactatgta ggtggaaaac ttggttcaaa
     6781 tcaatgttaa taagaacatc gcagttgagg gcaaccgttt ggtttgagcc agaacgtttc
     6841 aaataagtaa gaagctgttg gtagtattct tttccaactg tactactttc tacacgggta
     6901 ttgtaaattc ctagatagta atggctaaga agggttgata agccccactc gcgtcctgaa
     6961 cgaatatggt caaatactga gctgatatta tcctgctgga aaataccaaa gacactacga
     7021 acacctgcat tagcaaggct tgaaagtggg aagtcaatca aacgatattt cccaccaaat
     7081 ggcaaacttg ctactggacg gtggtccgtc aatgtcgaca tattgtgaaa accaactgta
     7141 tttcctaaaa tggcagaata tttatcaatc ttcatctgtt gctaccccca ctacttcatt
     7201 atatcctaca acttgtactt catctgttcc atcaatttcg acaccgtcag aaataatcgc
     7261 accttcacca ataatggcac gtttaatctt agctccttga ccaatgatag ctccactcat
     7321 gataactgaa tcaaggactt ccgctccttc gcgaacttgc gcgcctgttg aaaggataga
     7381 atgtttaaca gttccatcaa cgaaacatcc gtctacaact aatgagtctt ccacatgagc
     7441 atttgccccg aggaagtttg gtggtgaaat caagtttctt gagtaaatct tccattgacg
     7501 gttacgacta tccaaggcat tttctggaga aatatactcc atgttcgctt cccaaagtga
     7561 ctcaatagta ccaacatctt tccaataacc actaaattca taagcataaa cactttcacc
     7621 tgactcaagg taatttggaa tgacattttt accaaagtct gacatgccaa ccttgctctt
     7681 ttcagcagcg actaacatat tacgaaggcg ttgccaatca aaaatgtaga ttcccataga
     7741 agcttttgta gatttaggtt gagctggttt ttcttcaaat tcaacaatac gattgttagc
     7801 atctgtgttc atgataccaa aacggcttgc ttctttaaga gggacgtcta aaactgctac
     7861 tgtcaagctg gcattattat ccttatgaga ctggagcata tcatcatagt ccattttgta
     7921 gatgtggtcc ccagacaaaa tcaagacata ctcaggattg acactgtcga tatagtcgat
     7981 attttggtaa atagcgtgac tagtcccctc aaaccaacga tttccttcac ttgcagaata
     8041 aggttgaaga atagagacac ctgaattaat accgtctagt ccccagcttg aaccattccc
     8101 aatatggttg ttgagagcaa gtggttgata ctgtgtaacg accccaacat tatgaatccc
     8161 tgagttggca cagtttgata gggcaaagtc aatgatacgg tagcgcccac caaattgcac
     8221 agctggtttt gcgatgcttt gagtgagttt accgagacga gttccttgcc caccagcaag
     8281 aatcaaagct aacatttcat ttttcatttt ctactccttt ttggttttta tttgtgacgg
     8341 ttttagtaga tttcaagcga cgtttgattt tccatacact tgctcccata gccggtagag
     8401 taaaggttaa ggtctgctca taatctttcc atagtccttc ttgcgtttga acagtttgat
     8461 tatgttcttt ccaaacgcct ccccactctt ccaactcagt attccatact tcttcgtaaa
     8521 ttcctgcaac gggtagtccg attgtaaaat ctttccgctc aacaggtacc atattaaaga
     8581 tacagactaa catttctccc tttttaccct tacgaataaa ggaaagaaca ctctggtctc
     8641 gattatccgc atcaatgatt tcaataccat catagctggt atcaatttcc cacagacagc
     8701 gatgatcttt gtaaaactgg tttagctgag aagcgaaata cttcatctta gcattcattg
     8761 ggtcttctag gttagaccat tccaactgtt cttcagattt ccattctagg aattgaccgt
     8821 attcgctacc catgaagagc aatttcttac cagggtgaca aatttggtac gtatagagat
     8881 tgcgcaagcc tgcgaattga ttgtaacgat ctccccacat cttatgcatc atactcttct
     8941 tgccatgaac cacttcatcg tgcgagaatg gcaagagata attctccttg aaaacataca
     9001 taaagctgaa agtcaccagg ttaaagtcat atttacgata aatcggatct tcttcgtaga
     9061 aacggaggat atcattcatc cagcccatgt tccatttgta gtcaaatcct agactaccaa
     9121 tctctttcat tcccgtaatc ttggtcgcag acgaactttc ttctgcaatc atcatcacat
     9181 ctggatattc taacttaata acttcattca agcgttgaag aaaataataa ccttcatagt
     9241 tgagatttcc gccatcttta ttaggtgtcc atggagcatt atcatagtcc aaatagagca
     9301 tgttgctaac agcatccaca cgaataccat ccaaatgata gacatcaatc caatgcttaa
     9361 tgcaagaaat taagaaggac tggacttcat tttttccaag gtcaaaatta agggcacccc
     9421 aaccatggtt atgagcctta ttatggtctt ggtattcaaa agtcggtgtc ccatcataat
     9481 aggctaaggc atcatcgttg atggtaaagt gacctggtac ccagtccaca ataaccccaa
     9541 tattatgggt atgacactcc tcgacaaaat cttgaaactc ctctggtctg ccataagcat
     9601 gctctaaagc gaagtaaccc ataagctgat acccccaact caagcccaaa ggatgggaca
     9661 tcaagggcat aaactcaata tgagtatagt tcatttcaac gagataagga atgagttcat
     9721 ccttgagctg ggcaaaacta taaggactgc catcagaatt tcttttccat gatccagcgt
     9781 gaacttcata aatattgaca ggacgctctt caaagcccca acgttttctt cgtgccagcc
     9841 aaagtccatc cttccatttc ttctcaggaa gctctgttaa gattgcccct gttcctggac
     9901 gagcctcata cctgacagca aaagggtcaa tcttcatcag ttgatgacca ttttgacgtg
     9961 tgacatgata tttgtaaata tgcccttctt gagccatatt ggtaaagact tcccagaccc
    10021 caaaatcatt tcttaccatt ggaatctgat tttcaatcca gttggtaaaa tcaccaacca
    10081 agtgaacagc ctgagcatta ggtgcccaaa cacggaaggt atagccatgc tctccattta
    10141 gttcttccct atgtgctcct agataatgtt ggagataaaa attttcaccc gtcataaagg
    10201 tttttaatgc ttctctatta tccatatact ccccttctac tgtaagcgtt ttctatgttt
    10261 ttattatact acctttttag agaagattca agtaaattac tatacttctt taattatttt
    10321 gaaaatctac aacaagttca cttactcgtt caattgtaaa tcaatatttt ttcaaaaaat
    10381 tgcgaaaacg cctttctttt tctactatag tgaaatgaaa taaaacatgc gcaagtcgat
    10441 taaggaattt aatctaattt ctaacaatgt cttagaaatc aaagtgtact attttaactt
    10501 caatgtacta ta
//
LOCUS       DAVBOD010000071         9704 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 640-05
            SAMEA1012484-rid20186543.denovo.071, whole genome shotgun sequence.
ACCESSION   DAVBOD010000071 DAVBOD010000000
VERSION     DAVBOD010000071.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012484
            Sequence Read Archive: ERR059358
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9704)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9704)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979948.1
            Genome Coverage       :: 595x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:03:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,266
            CDSs (total)                      :: 2,219
            Genes (coding)                    :: 2,091
            CDSs (with protein)               :: 2,091
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 71 of 128
            Pseudo Genes (incomplete)         :: 50 of 128
            Pseudo Genes (internal stop)      :: 33 of 128
            Pseudo Genes (multiple problems)  :: 22 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9704
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012484-rid20186543.denovo.071"
                     /strain="NIG 640-05"
                     /db_xref="taxon:1313"
     gene            198..293
                     /locus_tag="VQ862_001893"
                     /pseudo
     CDS             198..293
                     /locus_tag="VQ862_001893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(546..1166)
                     /locus_tag="VQ862_001894"
     CDS             complement(546..1166)
                     /locus_tag="VQ862_001894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000780815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HET3116188.1"
                     /translation="MKLYFVRHGRTLWNQEGRFQGASGDSPLLPESIETLKRLGQYLK
                     EIPFDQIYSSDLPRAVKSAEIIQSQLHTPCSLEIVPNLREWQLGKLEGLKIATLEAIY
                     PQQIQAFRSNLAQFDTRMFGAESLYSTTQRTIQFIKSLKDSPAERILIVGHGANLTAS
                     LRTLLGYKEPLLRKDGGLANASLTIIETHDFETFTLNTWNDTSYQS"
     gene            complement(1166..1648)
                     /locus_tag="VQ862_001895"
     CDS             complement(1166..1648)
                     /locus_tag="VQ862_001895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA deacylase"
                     /protein_id="HET3116189.1"
                     /translation="MAKKVKIKKTLVEQILSKAAIPHQGIQINALEGELPQGYERDQI
                     FKTLALLGDKTGPIIGIVPITQHLSEKKLAKISGNKKVSMIPQKDLEKTTGYIHGANN
                     PVGIRQKHNYPIFIDKIALDLDRMIVSAGEVGHSIIVAPQDLASFVKADFVDILEDIK
                     "
     gene            complement(1648..2490)
                     /locus_tag="VQ862_001896"
     CDS             complement(1648..2490)
                     /locus_tag="VQ862_001896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF368 domain-containing protein"
                     /protein_id="HET3116190.1"
                     /translation="MLSWLARVIKGIVIALGFILPGISGGVLAAILGIYERMIGFLAH
                     PFKDLKENVLYFIPVAIGMLLGIGLFSYPIEYLLENYQVFVLWSFAGAIIGTVPSLLK
                     ESTRESDRDKIDLAWLWTTFIISGLGLYALNFVVGTLSASFLNFVLAGALLALGVLVP
                     GLSPSNLLLILGLYAPMLTGFKTFDLLGTFFPIGIGAGATLIVFSKLMDYALNNYHSR
                     VYHFIIGIVLSSTLLILIPNAGNAESIQYTGLSLVGYVIIAFFFALGIWLGIWMSQLE
                     DKYK"
     gene            complement(2585..3385)
                     /locus_tag="VQ862_001897"
     CDS             complement(2585..3385)
                     /locus_tag="VQ862_001897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 25 protein"
                     /protein_id="HET3116191.1"
                     /translation="MRKQIHPLILFSFFGIMMFILIINRPLNDNQSFKTKSNIAQIEA
                     QALKHLDKPIIDLSGWQRPEEINYDALSQNISGAIVRVHSGAQTTKENDASFINGIDK
                     AYKSHITELQKRNVPVAVYAYVAGKSVQEMEKAAEVFYNAASPYSPSYYWLDVEDKTM
                     SNMNEGVENFRAKLASLGAKNIGIYVGVYFMEEHSIDTGKFTSVWIPSYGSDSGFLES
                     SPKTDLDYDIHQYTSKGKIAGFDHDLDINVISPLKNKEETFRKLFLKP"
     gene            3529..4908
                     /gene="glmU"
                     /locus_tag="VQ862_001898"
     CDS             3529..4908
                     /gene="glmU"
                     /locus_tag="VQ862_001898"
                     /EC_number="2.3.1.157"
                     /EC_number="2.7.7.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000073762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional UDP-N-acetylglucosamine
                     diphosphorylase/glucosamine-1-phosphate
                     N-acetyltransferase GlmU"
                     /protein_id="HET3116192.1"
                     /translation="MSNFAIILAAGKGTRMKSDLPKVLHKVAGISMLEHVFRSVGAIQ
                     PEKTVTVVGHKAELVEEVLAGQTEFVTQSEQLGTGHAVMMTEPILESLSGHTLVIAGD
                     TPLITGESLKNLIDFHINHKNVATILTAETDNPFGYGRIVRNDNAEVLRIVEQKDATD
                     FEKQIKEINTGTYVFDNKRLFEALKNINTNNAQGEYYITDVIGIFRETGEKVGAYTLK
                     DFDESLGVNDRVALATAESVMRRRINHKHMVNGVSFVNPEATYIDIDVEIASEVQIEA
                     NVTLKGQTKIGAETVLTNGTYVVDSTIGAGAVITNSMIEESSVADGVTVGPYAHIRPN
                     SSLGAQVHIGNFVEVKGSSIGENTKAGHLTYIGNCEVGSNVNFGAGTITVNYDGKNKY
                     KTVIGDNVFVGSNSTIIAPVELGDNSLVGAGSTITKDVPADAIAIGRGRQINKDEYAT
                     RLPHHPKNQ"
     gene            4918..5463
                     /locus_tag="VQ862_001899"
     CDS             4918..5463
                     /locus_tag="VQ862_001899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000393791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HET3116193.1"
                     /translation="MEFEEKTLSRKEIYQGPIFKLVQDQVELPEGKGTAQRDLIFHNG
                     AVCVLAVTDEQKLILVKQYRKAIEAVSYEIPAGKLEVGENTAPVAAALRELEEETAYT
                     GKLELLYDFYSAIGFCNEKLKLYLASDLTKVENPRPQDEDETLEVLEVSLEEAKELIQ
                     SGHICDAKTIMAVQYWELQKK"
     gene            5475..5789
                     /locus_tag="VQ862_001900"
     CDS             5475..5789
                     /locus_tag="VQ862_001900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="foldase"
                     /protein_id="HET3116194.1"
                     /translation="MGKSLLTDEMIERANRGEKISGPPLLDDNEETKILPTSSSRFGY
                     ANPKDHGFSQETLKIQVEPSIHKSRRIENTKRNVFNSKLNKILFAVIFLLILLVLAMK
                     LL"
     gene            5806..6498
                     /locus_tag="VQ862_001901"
     CDS             5806..6498
                     /locus_tag="VQ862_001901"
                     /EC_number="3.2.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'-methylthioadenosine/adenosylhomocysteine
                     nucleosidase"
                     /protein_id="HET3116195.1"
                     /translation="MKIGIIAAMPEELAYLVQHLDNAQEQVVLGNTYHTGTIVSHEVV
                     LVESGIGKVMSAMSVAILAVHFQVDALINTGSAGAVAEGIAVGDVVIADKLAYHDVDV
                     TAFGYAYGQMAQQPLYFESDKTFVAQIQESLSQLDQNWHLGLIATGDSFVAGNDKIEA
                     IKSHFPEVLAVEMEGAAIAQAAHALNLPVLVIRAMSDNANHEANIFFDEFIIEAGRRS
                     AQVLLTFLKALD"
     gene            6575..7066
                     /gene="rocS"
                     /locus_tag="VQ862_001902"
     CDS             6575..7066
                     /gene="rocS"
                     /locus_tag="VQ862_001902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000021242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein RocS"
                     /protein_id="HET3116196.1"
                     /translation="MSIEMTVSEIAEVLGLSRQAINNRVKELPEEDTDKNDKGVTVVT
                     RSGLIKLEEIYKKTIFEDEPVSEDVKQRELMEILVDEKNAEILRLYEQLKAKDRQLSE
                     KDEQMRIKDRQIAEKDKQLDQQQQLTLQAMKDQENLKLELDQAKEEVQSTKKGFFARL
                     FGG"
     gene            7140..7730
                     /locus_tag="VQ862_001903"
     CDS             7140..7730
                     /locus_tag="VQ862_001903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exonuclease"
                     /protein_id="HET3116197.1"
                     /translation="MERLEDYIAFDLEFNQHEGQTHLIQVSAVRFRDGREIDAYDSYV
                     HTSVPLKSFINGLTGITAETLKDAPPVEKVLEEFQEFVGSLLMIGYNAAKSDLPILAE
                     HGLDYSQQYKVDLYDEAFERRSSDLHGIANLKLQTVASFLGFQGQSHNSLEDARMTAR
                     VYESFLESDQARELLETESSLSNNPFGVLDLSQLFD"
     gene            7739..9502
                     /locus_tag="VQ862_001904"
     CDS             7739..9502
                     /locus_tag="VQ862_001904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000801733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HET3116198.1"
                     /translation="MKPEKPKKLGLKQIYLNLDKILFLFFLIFMIVEYLWVPFNSWLA
                     SFLLDQTGYLFISYNNVLAILTHSPLISLAFLALIVINLLVAYFQIGLLFIGARHLLY
                     NEKRRLIEYIRKVFHESFGFMKKLTGAKALFIFFYIAMLFPFIRKMLKIYYLNKIVIP
                     EFIQAYLEDRYWMWWLSILLLSLIFLYVSVRLMFALPKIVYDQLTVREAVMFSLEKTK
                     KRVTFYAWNLFYILLKAHLLFYLPLIPLLLAQTLVDDITQRESLILGILNFVVIKNLY
                     YMALTYFLVKFVSFLTGKELDMLPRREKDHIVRWGVMTCASLFFALEGYIYLEAPMVH
                     LPQLISHRGVSNANGIQNTVESLETTAQLKPDLVETDVQETKDGQFVMMHDANLKNLA
                     GINKSPQDLNLEELKGIDIFENGYQTKISSFEDYLSRANELGQKLLIEIKTSKKDSPD
                     MMNRFLARYAAKLKIYGHQIQSLDYHVVEKVRQYDAELPVYFIMPYNFVFPKTRATGY
                     TMEYSTLDEYFVSKLWTTDQKLYVWTVNDSEAISKSLHLGVDGVITDDLEKVQREIEV
                     AQEDPEYTDLLLKKALEFFEF"
BASE COUNT         3004 a         1685 c         2068 g         2947 t
ORIGIN      
        1 taattttaaa gactttttga ccagcctcat ttttttaact tgatactcag tgaaaagcaa
       61 agattaaact aggaagctag ctgtaggctg ctcaaagaac agctttgagg ttgcagataa
      121 aacttgtgag gtaaccaaca tatataatgt gaagctgacg tggtttgaat agattttaga
      181 agggtatgag tctggaagtt ttaatggata atgcaagatt ccatagaatg ggtaagctag
      241 agttcttatg tgaagagttt gggcataaac ttttaccttt tcctccctac tcatattagt
      301 atagaaaagt gaatctaaaa tagtacataa ctgcttctaa aacattctta taaattgatt
      361 taaattctca aatcatatta ttcagttctt atttcatttt gctctacaat cctgttgaga
      421 agacacgtgt tcatatcaaa aaggtattgg caagttgaaa taccttttta caaggttctt
      481 ttgtcttatt tttgtttcaa ctgactatat ctcctatggt tctagttcag aaggctaggc
      541 tataattatg attgataaga agtatcattc caagtattga gagtgaatgt ttcaaaatca
      601 tgggtttcta taatggtcag gctggcattt gctagaccgc catctttacg aagaagtggt
      661 tctttatagc ctaggagagt acgaagactg gcagtaagat tggcgccgtg tccgacaatt
      721 agaatacgct cagctggact atcttttaat gatttgataa attggatggt ccgctgagtt
      781 gtactataga gggattcggc tccgaacatt cgagtgtcaa attgagcaag atttgaacga
      841 aaagcctgga tttgttgcgg gtaaatagct tccagggttg caattttcaa accttctaac
      901 ttcccaagtt gccattcacg gagattagga acgatttcta aagaacaggg ggtatggagt
      961 tgactttgga taatctcagc agatttgacc gctcgaggta aatcacttga ataaatctga
     1021 tcaaaaggaa tttccttgag atactgacca agtcgtttta gggtttcaat ggattcagga
     1081 agaagaggag aatcaccgct agcaccttga aaacgacctt cttggttcca gagggtacga
     1141 ccgtggcgga caaagtagag tttcattact tgatgtcctc caaaatatct acaaaatctg
     1201 cctttacaaa gctagccaag tcttgtggcg cgacgataat gctgtgtccg acttcgcctg
     1261 cagagacaat cattcgatcc aaatctagag caattttatc gataaaaatg ggataattgt
     1321 gtttctgacg aattccgaca ggattattgg ctccatgaat gtaaccagtt gttttttcta
     1381 agtccttttg tggaatcatg ctcacttttt tattgccaga aattttagct agtttctttt
     1441 cagacaagtg ctgagtgata gggacaattc cgataatcgg tccggtcttg tctcccaaaa
     1501 gcgccaaggt tttgaaaatc tgatctcgtt cataaccttg aggaagctct ccttctaggg
     1561 cattgatttg aatcccctga tgagggatag ctgctttaga taggatttgt tccaccaatg
     1621 tttttttgat tttaactttt tttgccatta tttatattta tcctccaatt gactcatcca
     1681 aataccaagc cagattccca gcgcaaagaa gaaggcgatg atgacataac cgacaagtga
     1741 aagtcctgtg tattggatac tttcagcgtt tcctgcattt ggaattaaga tcaaaagggt
     1801 acttgatagg acgataccga tgatgaaatg atagacgcgt gagtggtagt tgtttaaggc
     1861 ataatccatc aattttgaaa aaacgatgag agttgcacct gcaccaattc caatcggaaa
     1921 gaaggttccc aagagatcaa aagttttaaa accagtcaac ataggagcat agagtcccaa
     1981 aatcaaaagt aaattcgatg ggctgaggcc aggaaccaag acgccaaggg ccaatagtgc
     2041 gcctgctagg acgaagttaa gaaagctggc gcttaaggtt ccaacgacaa aatttaaggc
     2101 atatagtcct aatccagaaa tgataaaggt tgtccataac caagctaaat caatcttgtc
     2161 tcggtcagat tctcgagttg attctttgag gaggctagga actgtaccga taatagctcc
     2221 cgcaaagctc cataatacaa agacctgata attttcaagc aggtattcaa tcgggtagga
     2281 aaataagccg attcccagaa gcataccgat ggcaactgga ataaagtaca aaacattttc
     2341 tttaaggtct ttaaagggat gggccagaaa gccaatcatt cgttcataga ttcctaagat
     2401 tgctgctaga actcctccgg aaattcccgg taggataaat ccaagagcaa ttacaatccc
     2461 tttaataacg cgtgctaacc atgagagcat atatttcctc caactatttc tatttcaaaa
     2521 aatccttact atattgtatc acaatcagac acaaaaagaa aaagcaaatg ataaacaaat
     2581 gcttttaagg ttttaaaaaa agctttcgaa aggtttcttc tttatttttt aagggagaga
     2641 taacgttgat atctaaatcg tggtcaaagc cggcaatttt tcctttagat gtgtattggt
     2701 gaatatcata atctaaatca gttttaggac tgctctccaa aaatcctgag tctgagccgt
     2761 aggacggaat ccaaacagag gtaaacttgc ctgtatcaat actgtgttct tccatgaagt
     2821 agacaccaac gtagatgccg atgtttttag cacctagtga tgctagtttt gctcgaaagt
     2881 tttcgacacc ttcgttcata ttagacatgg ttttgtcttc cacgtcaagc caatagtaac
     2941 tagggctgta aggagaggca gcattgtaga aaacttcggc agccttttcc atttcttgga
     3001 cactttttcc agctacataa gcgtagacag caactgggac attccgcttt tgaagttcag
     3061 tgatatgact cttataggcc ttgtctattc cattgataaa tgaagcatca ttttcttttg
     3121 tcgtttgagc accactgtga acacgaacaa tagcacctga aatattttgt gagagggcat
     3181 cgtagttgat ttcctcagga cgctgccagc cagagaggtc aataatcggt ttgtctaagt
     3241 gtttcaaagc ctgtgcttca atctgtgcta tattggattt tgttttaaac gattggttgt
     3301 cattaagtgg gcgattgatg attaaaatga acatcataat cccaaaaaaa ctaaataaaa
     3361 taagtggatg aatttgtttt ctcatatctt ataattctac cctaaaaatc aaaaaaaatc
     3421 aaaaaaatgg gttaaggaag agactttaga gcattttttc attcaagagt gcggaatgat
     3481 ttgaaatatg gtataataaa agggaatttc tacagaaaag agaagattat gtcaaatttt
     3541 gccattattt tagcagcggg taaagggact cgcatgaaat ctgatttgcc aaaagttttg
     3601 cacaaggttg cgggtatttc tatgttggaa catgttttcc gtagtgtggg agctatccaa
     3661 cctgaaaaga cagtaacagt tgtaggacac aaggcagaat tggttgagga ggtcttggct
     3721 ggacagacag aatttgtgac tcaatctgaa cagttgggaa ctggtcatgc agttatgatg
     3781 acagaaccta tcttagaaag tttgtcagga cacaccttgg tcattgcagg agatactcct
     3841 ttaatcactg gtgaaagctt gaaaaacttg attgatttcc atatcaatca taaaaatgtg
     3901 gccactatct tgactgctga aacggataat ccttttggct atggacgaat tgttcgtaat
     3961 gacaatgctg aggttcttcg tattgttgag cagaaggatg ctacagattt tgaaaagcaa
     4021 atcaaggaaa tcaacactgg aacatacgtc tttgacaaca agcgtttgtt tgaggctttg
     4081 aaaaatatca ataccaataa cgctcaaggc gaatactata ttacagacgt cattggtatt
     4141 ttccgtgaaa ctggtgaaaa agttggcgct tatactttga aagattttga tgaaagtctt
     4201 ggggtaaatg accgtgtggc gcttgcgaca gctgagtcag ttatgcgtcg tcgcatcaat
     4261 cataaacaca tggtcaacgg tgttagcttt gtcaatccag aagcaactta tatcgatatt
     4321 gatgttgaga ttgcttcgga agttcaaatc gaagccaatg ttaccttgaa agggcaaacg
     4381 aaaattggtg ctgagactgt tttgacaaac ggtacttatg tagtggacag cactatcgga
     4441 gcaggagcgg tcattaccaa ttctatgatt gaggaaagta gtgttgcaga cggtgtgaca
     4501 gtcggtcctt atgctcacat tcgtccaaat tcaagtctgg gtgcccaagt tcatattggt
     4561 aactttgttg aggtgaaagg atcttcaatc ggtgagaata ccaaggctgg tcatttgact
     4621 tatatcggaa actgtgaagt gggaagcaac gttaatttcg gtgctggaac tattacagtc
     4681 aactatgacg gcaaaaacaa atacaagaca gtcattggag acaatgtctt tgttggttca
     4741 aattcaacca ttattgcacc agtagaactt ggtgacaatt ccctcgttgg tgctggttca
     4801 actattacta aagacgtgcc agcagatgct attgctattg gtcgcggtcg tcagatcaat
     4861 aaagacgaat atgcaacacg tcttcctcat catcctaaga accagtagga gcctatcatg
     4921 gagtttgaag aaaaaacgct tagccgaaaa gaaatctatc aaggaccaat atttaaactg
     4981 gtccaagatc aggttgaatt accagaaggc aagggaactg cccaacggga tttgattttc
     5041 cacaatgggg ctgtctgtgt tttagcagta acggatgaac aaaaacttat cttggtcaag
     5101 cagtaccgca aagctatcga ggctgtctct tacgaaattc cagccggaaa attggaagta
     5161 ggagaaaaca cagcccctgt cgcagctgcc cttcgtgaat tagaggaaga aacagcctat
     5221 acagggaaat tagaactctt gtacgatttt tattcagcta ttggcttttg taatgagaag
     5281 ttaaaactat atttagcaag cgatttgaca aaagtggaaa atccgcgtcc gcaggatgag
     5341 gatgaaacct tggaagtcct tgaagtgagc ttagaagaag cgaaagaatt aatccaatca
     5401 ggtcatatct gtgatgccaa gacaattatg gctgttcagt attgggagtt gcagaaaaaa
     5461 tagaggaggt cagtatgggt aaatctttat taacggatga aatgattgaa agagctaata
     5521 gaggcgaaaa aatttcaggt cctcctttgc tggatgataa tgaggaaact aagattttac
     5581 caacctcttc ttcccgtttt ggttatgcca atcctaagga tcatggtttt agccaggaaa
     5641 ccttgaagat tcaggtcgaa ccatctattc ataaaagccg tcgcattgaa aataccaaga
     5701 gaaatgtctt caattctaag ttgaataaaa tcttattcgc ggtcatcttt ctcttgattt
     5761 tgcttgtttt agcaatgaaa cttttgtaat agaaaaggaa ttgaaatgaa aataggaatt
     5821 attgctgcta tgccagaaga actggcttat ctggtccagc atttagacaa tgcccaggag
     5881 caagttgttt tggggaatac ctatcataca ggaaccattg tttctcatga agtcgttctt
     5941 gtagaaagtg gaattggtaa ggtcatgtct gctatgagtg tggcgatttt ggctgttcat
     6001 ttccaggtgg atgcccttat taatacgggt tcagctgggg cagtagcaga aggtatcgct
     6061 gttggggatg tcgtgattgc tgacaaatta gcctatcatg acgtggatgt cacagctttt
     6121 ggctatgctt atggacaaat ggcgcaacaa ccgctttatt tcgaatcaga caaaaccttt
     6181 gttgctcaaa tccaagagag tttatctcaa ttggaccaaa actggcatct tggtttgatt
     6241 gctacaggag atagttttgt tgcaggaaat gacaagatag aagcgattaa gtcccatttc
     6301 ccagaagttt tagccgtgga gatggagggg gcagctattg ctcaagcagc gcatgccctc
     6361 aatctcccag tcttagtcat cagagctatg agtgacaatg ccaaccatga agcaaacatc
     6421 ttttttgatg agtttattat cgaagctgga cgtcgctctg cccaagtctt gttgaccttt
     6481 ttgaaggctt tagattaagc ggaaatttga cagtttttct agcttatgat aagatttaag
     6541 taaagaaaag ctagaaaacg tttcagagga tattatgagt attgaaatga ccgtcagtga
     6601 gattgcagag gtcttaggat tatctcgcca agcaatcaat aaccgtgtca aagaattacc
     6661 agaagaagac acagataaaa atgacaaagg ggtaacagtt gttaccagaa gtggcttgat
     6721 taagctagaa gaaatctata aaaaaacgat ttttgaagat gagcctgtca gtgaagatgt
     6781 caaacaacgt gaactgatgg agattctagt ggatgagaag aatgcagaaa ttcttcgtct
     6841 ttatgaacaa ttaaaagcca aggatcgtca gttatcagaa aaagacgagc agatgcgtat
     6901 caaagaccgt cagattgctg agaaagacaa acaattagat cagcaacaac aattgaccct
     6961 tcaagccatg aaggatcaag aaaatcttaa gctagagctg gaccaagcaa aagaagaagt
     7021 ccaatccact aagaaaggct tttttgctcg tttatttgga ggataatcaa ggagctgttt
     7081 aggttaaatg ctaacctgat ggcttctttt gtttgtgaat agtagaggag aggtacagaa
     7141 tggaacgatt agaagattac attgcttttg acttagaatt taatcagcac gaaggacaaa
     7201 cacacttgat tcaagtatcg gcagtgcgtt ttagagatgg tcgggaaatc gatgcctatg
     7261 attcctatgt tcataccagc gtccctctaa aaagctttat caatggtttg accgggatta
     7321 cagctgagac cttaaaagat gctcctccag ttgagaaagt cttagaagaa ttccaagagt
     7381 ttgtgggttc tttgctgatg ataggctaca atgctgctaa aagtgattta cctattttag
     7441 cagagcatgg tttagactat agccaacagt acaaggtgga tttgtatgat gaagcttttg
     7501 aacgtcggag ttcagattta catggtattg ccaatctcaa attgcaaact gttgcctcat
     7561 ttcttggatt tcaaggtcag tctcataata gtttagagga tgctcggatg acggcgcgtg
     7621 tttacgaatc cttcttagag tcggatcaag ctagggaatt gttagagaca gaaagtagct
     7681 tatcaaacaa tccttttggt gtcttggact tgtctcaatt atttgactag gagtgcctat
     7741 gaaacctgaa aaacctaaaa aattgggtct taaacagatt tacctcaatc ttgataaaat
     7801 cctctttcta tttttcttga tttttatgat agtggagtat ttgtgggtac cattcaattc
     7861 atggttggct agcttcttat tagatcagac aggttatctt tttatttcct ataacaatgt
     7921 cttagccatc cttactcatt ctccattgat tagtctagct tttttagcct tgattgtaat
     7981 taaccttctg gttgcttatt ttcaaatagg actcctcttt attggtgctc gtcatctcct
     8041 ctataatgaa aagcgaaggc taattgagta tatccgcaag gttttccatg aaagttttgg
     8101 atttatgaaa aagctaactg gcgctaaagc cttgtttatc tttttctata tagctatgct
     8161 gtttcctttt atacggaaaa tgctgaagat ttattatctt aataaaatcg tcattccaga
     8221 gtttatccaa gcttatttag aagatagata ttggatgtgg tggctgagca tcctacttct
     8281 atctcttatc tttctctatg tctctgtcag attgatgttt gcccttccga agattgtata
     8341 tgatcagctg actgttcgag aagcagtgat gtttagcttg gagaaaacca agaagagagt
     8401 tactttttat gcttggaatt tattttacat cttgctcaaa gcacatttat tattttatct
     8461 tcctttgatt cctttattat tggctcaaac tttggtagat gatatcactc agagagagtc
     8521 tctgattctt ggtattttga attttgtcgt gattaaaaat ctctattata tggctctgac
     8581 ttattttttg gttaaatttg tttcattttt gacaggaaag gagctggata tgcttcctag
     8641 gagagaaaaa gatcacatcg tgcgatgggg tgtcatgact tgtgccagtc ttttctttgc
     8701 cttagaaggt tatatttatc tggaggctcc catggttcat ctacctcaac ttatttctca
     8761 ccgaggggtt tccaatgcaa atgggattca aaatacagta gagtccttgg aaactacagc
     8821 acaactcaaa ccagacttgg tggagacgga cgtgcaggaa acaaaagatg ggcagtttgt
     8881 catgatgcat gatgctaact tgaaaaatct agcaggtatc aataaaagtc ctcaagactt
     8941 aaacttggag gagcttaaag ggattgatat ttttgaaaat ggctaccaga ctaaaatttc
     9001 aagctttgaa gattatctca gtcgagccaa cgaacttggt caaaaattac taattgaaat
     9061 taaaaccagt aaaaaagata gtccagacat gatgaaccgc tttttagccc gttatgctgc
     9121 aaagctcaag atttatggac atcaaatcca gtctttagac taccatgttg tcgaaaaagt
     9181 aagacagtat gatgccgaac tgccagttta tttcatcatg ccctacaatt ttgtctttcc
     9241 taaaacaaga gcgacaggat atactatgga gtactcaacc ttggatgaat attttgtaag
     9301 caaactatgg acaacggatc agaaacttta tgtctggact gtcaatgatt cagaagctat
     9361 cagcaaatct cttcacttag gagtagatgg agtgattaca gatgatttgg aaaaagttca
     9421 gcgggaaata gaagtagccc aagaagatcc agaatatacg gatttgctct tgaaaaaagc
     9481 attggaattc tttgaatttt agtaataaaa aagaggaacg gttgttcctc ccatgatagg
     9541 taagtattct tgtgaatgct tgcttttttg tggttgcaat ccgtttacga gaattgtttg
     9601 tattgttctt gtttcaattt actttatagt gctttgaagt tggaatgcta cactataact
     9661 tataaaatat agtaaaatga accaaaaata gtacacaatg tggt
//
LOCUS       DAVBOD010000072         9425 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 640-05
            SAMEA1012484-rid20186543.denovo.072, whole genome shotgun sequence.
ACCESSION   DAVBOD010000072 DAVBOD010000000
VERSION     DAVBOD010000072.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012484
            Sequence Read Archive: ERR059358
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9425)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9425)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979948.1
            Genome Coverage       :: 595x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:03:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,266
            CDSs (total)                      :: 2,219
            Genes (coding)                    :: 2,091
            CDSs (with protein)               :: 2,091
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 71 of 128
            Pseudo Genes (incomplete)         :: 50 of 128
            Pseudo Genes (internal stop)      :: 33 of 128
            Pseudo Genes (multiple problems)  :: 22 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9425
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012484-rid20186543.denovo.072"
                     /strain="NIG 640-05"
                     /db_xref="taxon:1313"
     gene            complement(<1..252)
                     /locus_tag="VQ862_001905"
     CDS             complement(<1..252)
                     /locus_tag="VQ862_001905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000370958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HET3116199.1"
                     /translation="MDNVLLSLSEWIKSIIKDTITRLVEIEKDSDHYPELMDVNTTCD
                     FLGIKYATFSDNYRYLKGFPKELPGKKWSKRAIKEWLSNQ"
     gene            complement(265..978)
                     /locus_tag="VQ862_001906"
     CDS             complement(265..978)
                     /locus_tag="VQ862_001906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001002349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ORF6C domain-containing protein"
                     /protein_id="HET3116200.1"
                     /translation="MNEIFNFHGQEVRTLIIDDEPWFVGKDVADILGYSKARNAIALH
                     VDEDDALKQGLTDNLGRVQETIIINESGLYSLILSSKLPQAKEFKRWVTSEVLPAIRK
                     QGGFIREDLDEDAFIALFTGQKKLREQQATMLEDIDYLKSEQPIHPSYAKSLLKKRKA
                     RVVVCLGGIDSPAYADKTFAQSVFRQAEIDFKDHFNINRYDLLPKKFADAALAYWMTW
                     EPSTNTKMKIMKLNSFDEG"
     gene            1032..1457
                     /locus_tag="VQ862_001907"
     CDS             1032..1457
                     /locus_tag="VQ862_001907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000456432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3116201.1"
                     /translation="MEYQALIQPVISIILAIISGLWSYVASKANNKAEIEKQAKEHSH
                     TVEKLEREFHHQIDTLKQQHAFELEKIKQAHELRLQELEKVSQLDTETDKSMKMNDLT
                     YKVFTGEVDFDKALKIANKASNSKQNLNKRFIQKTSKKS"
     gene            complement(1452..1613)
                     /locus_tag="VQ862_001908"
     CDS             complement(1452..1613)
                     /locus_tag="VQ862_001908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001002946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3116202.1"
                     /translation="MNELVWFYFVVIINLIIGFATYYASKRDREKRINGFKKIQDDEL
                     ERVRNKFNL"
     gene            complement(1624..1821)
                     /locus_tag="VQ862_001909"
     CDS             complement(1624..1821)
                     /locus_tag="VQ862_001909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001066214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3116203.1"
                     /translation="MNNAAQKVTRIDKDAWEIATELANEYGVSICHIISESVRYCAEN
                     AEFKEMDVVVKRLVVGSKVLE"
     gene            complement(1838..2041)
                     /locus_tag="VQ862_001910"
     CDS             complement(1838..2041)
                     /locus_tag="VQ862_001910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HET3116204.1"
                     /translation="MSKELKIIKAKIKTRLIELDMTQVELAKQVSVASSVISELLKYG
                     KGSDYVKEKVVDILGIENPWENS"
     gene            complement(2034..2408)
                     /locus_tag="VQ862_001911"
     CDS             complement(2034..2408)
                     /locus_tag="VQ862_001911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000573356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3116205.1"
                     /translation="MIETLEIKINKKTYFISARADVPVRYKVMFGRNLFDDFSKIKNN
                     KDETLSLCLLFCMTDKSSEEFCKFFIENNSYITSRHHYEAIRLFEKHFIFKPVTYSLE
                     DIVQILTIYLENTKTQIGGKNE"
     gene            complement(2452..2598)
                     /locus_tag="VQ862_001912"
     CDS             complement(2452..2598)
                     /locus_tag="VQ862_001912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001001334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3116206.1"
                     /translation="MNEEDLKELLELLATDYGRGYLDGVVGGLSMLLKISKEAEKYRK
                     EKYE"
     gene            2883..3251
                     /locus_tag="VQ862_001913"
     CDS             2883..3251
                     /locus_tag="VQ862_001913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000464160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET3116207.1"
                     /translation="MFVAFDKIKELADKQGISINILEEKLGYGTNTLYRLKRSNPSSK
                     VLKEIADYFNVSADYLLGRTDNPAIAGSDEFAQVNGQIIDLRKAAANTMLFDGKPLNE
                     DDIDFITSVLSAHFKSKGER"
     gene            3251..3484
                     /locus_tag="VQ862_001914"
     CDS             3251..3484
                     /locus_tag="VQ862_001914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3116208.1"
                     /translation="MTITINFTEKNSYITDYLTKHGIDTTTMDFDDFMVLMEDIEDAR
                     AADQAYMEYLADPATYTMDEVLDELGLSREDIA"
     gene            3484..3747
                     /locus_tag="VQ862_001915"
     CDS             3484..3747
                     /locus_tag="VQ862_001915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000285964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HET3116209.1"
                     /translation="MYRLDIDKKALKQLKKLDTPTRKQILSWLAKNIENTTNPRQHGK
                     ALKANLAGYWRYRVENYRIICDIQDDKLVVLAVEIAHRRDVYK"
     gene            3760..4140
                     /locus_tag="VQ862_001916"
                     /pseudo
     CDS             3760..4140
                     /locus_tag="VQ862_001916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000170931.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
     gene            4178..4990
                     /locus_tag="VQ862_001917"
     CDS             4178..4990
                     /locus_tag="VQ862_001917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001174228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease"
                     /protein_id="HET3116210.1"
                     /translation="MQKTVEKILFRVAGVTKYKKAVKEACNMIAEDNGIPEYAKYYSN
                     LSTKELREELEEYGLKVFKYQDLDFFNIELVPEVDNRYDPNAIKVLIFDNHVGYVPAT
                     IAKTIRKYFDNKKYNFVIEGEIKGGPYKEWDEYEEKVVTNNDLDVGFEIYLTIVDSSQ
                     KEVIQSESSEIIDDNISNKEVTETEAIETKTTETEHIEQNIVSDSVADIVNEINLSET
                     SPKKKLPANKIIFSALYLFLVFFGVVGIPIAPFLAVPLTAWSLYKLYKLFRK"
     gene            5165..6313
                     /locus_tag="VQ862_001918"
     CDS             5165..6313
                     /locus_tag="VQ862_001918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000876726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HET3116211.1"
                     /translation="MKYNKTKYPNIYYYETAKGKRYYVRRSFFFRGKKREKSKSGFTT
                     LPQARAALVELEQQIQEQELGINTNLTLDQYWDIYSEKRLSTGRWNDTSYYLNDNLYK
                     NHIKAKFGSILLKNLDRNEYELFIAEKLQNHTRYTVQTLNSSFMALLNDAVKNGNLLS
                     NRLKGVFIGQSDIPAANKKVTLKEFKTWIAKAEEIMPKQFYALTYLTIFGLRRGEVFG
                     LRPMDITQNDSGRAILHLRDSRSNQTLKGKGGLKTKDSERYVCLDDIGTDLIYYLIAE
                     ASKIKRKLGIIKEQHKDYITINEKGGLINPNQLNRNFNLVNEATGLHVTPHMMRHFFT
                     TQSIIAGVPLEQLSQALGHTKVYMTDRYNQVEDELAEATTDLFLSHIR"
     gene            complement(6545..7831)
                     /locus_tag="VQ862_001919"
     CDS             complement(6545..7831)
                     /locus_tag="VQ862_001919"
                     /EC_number="6.3.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate synthase"
                     /protein_id="HET3116212.1"
                     /translation="MTSVVVVGTQWGDEGKGKITDFLSANAEVIARYQGGDNAGHTIV
                     IDGKKFKLHLIPSGIFFPEKISVIGNGMVVNPKSLVKELSYLHEEGVTTDNLRISDRA
                     HVILPYHIELDRLQEEAKGDNKIGTTIKGIGPAYMDKAARVGIRIADLLDKDIFRERL
                     ERNLAEKNRLFEKLYDSKAIVFDDIFEEYYEYGQQIKKYVIDTSVILNDALDNGKRVL
                     FEGAQGVMLDIDQGTYPFVTSSNPVAGGVTIGSGVGPSKIDKVVGVCKAYTSRVGDGP
                     FPTELFDEVGERIREVGHEYGTTTGRPRRVGWFDSVVMRHSRRVSGITNLSLNSIDVL
                     SGLDTVKICVAYDLDGQRIDYYPASLEQLKRCKPIYEELPGWSEDITGVRNLEDLPEN
                     ARNYVRRVSELVGVRISTFSVGPGREQTNILESVWS"
     gene            complement(8062..8298)
                     /locus_tag="VQ862_001920"
     CDS             complement(8062..8298)
                     /locus_tag="VQ862_001920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecX"
                     /protein_id="HET3116213.1"
                     /translation="MLQKIYEQMANFYDSIEEEYGPTFGDNFDWEHVHFKFLIYYLVR
                     YGIGCRRDFIVYHYRVAYRLYLEKLVMNRGFISC"
     gene            8563..9360
                     /locus_tag="VQ862_001921"
                     /pseudo
     CDS             8563..9360
                     /locus_tag="VQ862_001921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436304.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         3210 a         1932 c         1522 g         2761 t
ORIGIN      
        1 ttgattagag agccattctt tgatggctct ttttgaccat ttcttaccag gtaattcctt
       61 tggaaatccc tttaagtaac gataattatc tgaaaaggtg gcatacttaa ttcctagaaa
      121 atcacaggta gtgttcacat ccatcagctc tggatagtgg tcactatctt tttctatttc
      181 gactagcctt gtgattgtgt ccttgataat ggatttaatc cattcagaca gtgaaagtag
      241 aacattgtcc atcttcttcc cctcctaccc ttcgtcaaat gagttcaatt tcatgatttt
      301 catcttggta ttggtgcttg gctcccaagt catccaatag gccaaggctg catctgcgaa
      361 ttttttcggt agcaagtcat agcgattaat gttgaagtgg tctttaaagt caatctcagc
      421 ttgtctaaag actgactgag cgaaagtctt atccgcataa gccggactat caatgccacc
      481 taagcaaacc acgacccgag ccttacgctt cttcaggagc gatttagcat agcttgggtg
      541 aatcggttgc tcactcttga gatagtcaat atcttccagc atggtcgcct gttgctcacg
      601 taatttcttc tggccagtaa acagagcgat aaaggcatcc tcgtccaagt cctcgcgaat
      661 gaaaccgccc tgcttgcgaa tagctggcaa aacctctgat gtcacccagc gcttaaactc
      721 tttagcctga ggcaacttgc tggataagat aagagagtag aggccagatt cgttgatgat
      781 gatagtttct tgaacccttc ctaaattatc tgtgaggccc tgttttaggg cgtcatcttc
      841 atcaacatga agagcaatcg catttctagc cttgctatat cctaggatgt ctgcaacatc
      901 tttcccaacg aaccaaggtt cgtcatcaat gatcaaagta cggacttcct gcccgtgaaa
      961 attaaaaatt tcgttcataa agttcctttc taaatttggt ataattaaaa taaaacgatt
     1021 ggagaaatct tatggaatat caagctctta ttcaacctgt gattagtatt attcttgcaa
     1081 taatatcagg gttatggtca tatgtcgcat caaaagctaa caataaagct gagattgaaa
     1141 aacaagccaa agaacattca catactgttg aaaaactcga aagagaattt catcatcaga
     1201 tagatactct aaaacagcaa catgcctttg aacttgaaaa aatcaaacaa gctcatgaat
     1261 tacggttgca agaacttgag aaggtatctc agcttgatac tgaaaccgac aagtctatga
     1321 agatgaatga tcttacctac aaagttttta caggcgaggt tgattttgac aaagctttaa
     1381 aaatagctaa taaagcaagc aatagcaaac aaaacttaaa taaaagattt attcaaaaga
     1441 cttctaaaaa atcataaatt aaatttattt ctaactcttt caagctcatc atcttgtatt
     1501 tttttaaacc cgttgatgcg cttttctcta tctcttttgc tagcgtagta tgtagcaaaa
     1561 ccaatgataa gattgattat gacaacaaag taaaaccata ctagttcatt catctccacc
     1621 ctcctactcc agcaccttac tgccgactac caatcgttta acgacaacgt ccatctcctt
     1681 aaattcggca ttctctgcac agtagcggac gctctcgctg atgatgtgac aaatagatac
     1741 gccgtactcg ttcgccagct ccgtagcaat ctcccaggca tctttgtcaa tccgtgttac
     1801 tttttgcgct gcgttgttca tactatttcc tcatgctcta actattttcc caagggtttt
     1861 caatacccaa aatatctacg actttttctt tcacataatc acttcctttt ccatacttca
     1921 gcaactctga aataactgat gatgctacag atacttgttt tgccaattcg acttgagtca
     1981 tatccaactc aatcaaacga gttttaattt tagccttaat tatttttagt tctttactca
     2041 ttttttcctc caatctgtgt tttagtattt tctagatata ttgttaggat ttgaactatg
     2101 tcctctagtg aatatgttac gggcttaaag ataaaatgtt tttcaaataa tcttattgcc
     2161 tcatagtgat gtctacttgt tatatatgaa ttattttcaa taaaaaattt acagaattct
     2221 tctgacgatt tgtctgtcat acaaaataat agacaaagtg atagagtttc atctttattg
     2281 ttttttattt tcgaaaagtc atcgaagaga tttctgccaa acataacttt atacctgact
     2341 ggaacatctg cccttgcaga tatgaagtat gtctttttgt ttatttttat ttccagtgtt
     2401 tctatcattt cctacctcgt ttacctactt tatgtgacta ataattttgc tttactcata
     2461 tttttccttt ctatatttct ctgcttcttt tgaaattttc aaaagcattg aaagtccccc
     2521 aactactcca tctagatacc ctcgcccata atctgtcgct aagagttcca ataattcttt
     2581 caggtcttct tcgttcatcc ctgacctcct tttaaaaaat tatctaaaaa gttagcgaac
     2641 ttcttgacaa ctctagtcaa atgttttaaa ataaaaacat agagaaaaga cctactaaaa
     2701 gtaagtttta cctacagtaa acggacgcca atcagttttg taaggcttta ttttttagtt
     2761 gtctagttcg ctaactcttt agcttacgaa tattatttta aaacatttga ctaaataagt
     2821 caactatttt ctacaaatat tttaaaatta tttttcgttt gcttagaaag gttgaaaaat
     2881 taatgtttgt agcattcgat aaaataaaag aattagctga taaacagggg atttctataa
     2941 atattttaga agaaaaactt ggttatggaa ctaatacttt atatcgatta aaaagaagta
     3001 atcctagttc aaaagtttta aaagaaatag ctgattattt taatgtaagt gctgactacc
     3061 tactcggacg gacagataat cctgctatcg ctggaagtga tgaatttgct caagtaaatg
     3121 gacaaatcat agacttacgc aaagcagcag ccaacaccat gttatttgac ggaaaaccac
     3181 taaatgaaga tgatatcgac ttcatcacat ccgttctatc cgcccacttc aaaagcaaag
     3241 gagaacgcta atgactatca cgatcaattt cacagaaaaa aactcctaca tcacggacta
     3301 cctaaccaaa cacggtatcg acacaacaac catggatttt gacgacttca tggtactcat
     3361 ggaagatatc gaagacgcac gagcagccga ccaagcctat atggagtatt tagccgaccc
     3421 agctacttat accatggatg aggtcttgga tgaactagga ctatctcgag aggatattgc
     3481 ttaatgtatc ggctagatat tgataaaaaa gctctcaagc aacttaaaaa actagatacc
     3541 ccaaccagaa aacaaatcct atcctggctt gctaaaaaca ttgaaaacac gaccaatcca
     3601 cgacaacacg gaaaagcact aaaagccaac cttgcaggtt actggcgata cagagtagag
     3661 aattaccgca tcatctgtga tatccaagac gataaactag tcgtcctagc cgtggaaatc
     3721 gcccaccgca gagatgttta taaataacga aggagaacta tgatactcgc taaactctgc
     3781 gaagaatatc aagtagagct ttgtctcttc gacggttcaa actggcacag tagcggtttc
     3841 tacaatccag acacaaacgt actcgctatt gaccacaact tagctcctga acaacaaatc
     3901 caagtcgccc tacactaact cggacacaaa gaccatacac gctcagagta ccaaaacgct
     3961 cgcctacgct gtgaaaacga agctgatagg aatatgatcc atcatctcgt gaaagacgca
     4021 ctagaaagct tagacgaccc cacagagttt gattacctca aattcatgtc ttactacaat
     4081 ctaaaaacta tgactaatga agtcatggtc aaggaagagt acttggcatt agtaaattaa
     4141 aaattgcatt gaagatattt atatagaggg gaaatatatg caaaagactg ttgaaaaaat
     4201 attattcaga gtcgctggag tgacaaaata taaaaaagca gtaaaagaag cttgcaatat
     4261 gattgctgaa gataacggaa tcccagaata tgcaaagtac tatagcaatt tatcaactaa
     4321 ggaacttaga gaagaacttg aagaatatgg tctgaaagtt ttcaaatatc aagatttaga
     4381 ctttttcaat attgagctcg ttccagaagt agataataga tatgatccta atgctataaa
     4441 agttttgata tttgataatc atgtaggata tgttcctgca accattgcta aaacaatacg
     4501 aaaatatttt gataataaaa aatataactt tgtaatagag ggagagataa aaggtggccc
     4561 atataaagaa tgggacgagt atgaagaaaa agttgtcaca aataatgatt tggatgttgg
     4621 ttttgaaatt taccttacca ttgttgattc ttcacaaaaa gaagtaattc agagcgaatc
     4681 atctgagata attgatgata acatttccaa taaagaagtt acggaaactg aagctattga
     4741 aactaaaaca actgaaactg aacatattga acaaaatatt gttagtgaca gtgtcgctga
     4801 tatagtaaac gagattaatc tttcagaaac atctcctaag aaaaaacttc ctgccaataa
     4861 aatcatattt tcagcactgt atcttttctt agtctttttt ggagttgttg gtattccaat
     4921 cgctccattc cttgcagtcc ctttgacagc ttggagtttg tataaactat acaaactatt
     4981 cagaaaataa aaaaaaagcc ccacaatcgc cctcgccaaa gtttgattgt gaagcttacc
     5041 cttataaaaa atcagccatt aaaaaggcct cttttctata ccctatttta caccatgaaa
     5101 ggggtgatgt caatattctc aatgtttaga ccttgtccag aagccgataa acaaggagaa
     5161 tacaatgaaa tataataaaa caaaataccc aaatatctat tactatgaga ctgctaaagg
     5221 caagcgttac tatgtcagac gttctttttt cttccgaggt aaaaaaagag aaaaaagtaa
     5281 aagtggtttc acaactctcc ctcaagctcg tgcagccttg gtagagcttg agcaacaaat
     5341 ccaagaacaa gaattaggta tcaatacgaa tctaacgctt gatcaatatt gggatatcta
     5401 ttctgaaaag agattgtcaa cagggcgctg gaatgacact tcctactacc tcaatgacaa
     5461 tctctataag aaccatatca aggcaaagtt tggttctatc ctgcttaaaa atttggatag
     5521 aaatgagtat gaactattta tcgctgaaaa gttgcagaac cataccagat acactgttca
     5581 aaccctcaat tccagcttca tggcattgct gaatgatgcc gtcaaaaatg gaaatctgct
     5641 ctcaaatcgc ttgaaaggtg ttttcatcgg ccagagtgat atccctgctg caaacaagaa
     5701 agtgactctc aaagagttca agacttggat agcaaaggca gaagagatta tgccaaaaca
     5761 attctacgct ctgacctatc tgacaatttt tggattgaga agaggagaag tctttggatt
     5821 gcgtccaatg gacatcactc agaacgacag cggacgggct atactgcatc ttagagacag
     5881 tcgaagcaac cagaccttaa aagggaaagg agggcttaaa acgaaggatt cagagcgata
     5941 tgtctgcctt gatgatatcg gaacagacct gatctattat ctgatagctg aagcttctaa
     6001 gattaagcga aagttaggaa ttatcaagga acagcacaag gattatataa ctatcaacga
     6061 gaaaggtggt ctcatcaatc caaatcagct aaatagaaac ttcaatctag tgaatgaagc
     6121 aacaggattg catgtaacac ctcacatgat gcgccacttc ttcacgactc aaagcattat
     6181 tgcaggggtt ccgcttgaac aattaagcca ggcgctgggg catacaaagg tttatatgac
     6241 ggatcgttac aatcaagtag aggacgaact tgctgaagcg acaacagacc tatttcttag
     6301 tcatattcgc taaaaaagtc cccgccaatt ccccgaccaa aatccgaaaa atatcgaaaa
     6361 attattttta gaatagtccc caaaagcctg aaatagagct aaaaaactcc acctgattgg
     6421 gtggagttaa gggagattat tatgaaaaag aaaagtttag gatatttgtt acaacaagtt
     6481 aggaggtctt cttataactg tctatagtat acccgaccta tcttaaacaa atcttaaaaa
     6541 tctcttagga ccaaacactt tctaaaatat ttgtttgttc acgaccagga cctactgaga
     6601 aagtagaaat acgaacgcca accaattcac tcacacgacg aacatagtta cgcgcattct
     6661 caggaagatc ttccaaattg cgaactccgg taatatcttc tgaccaacct ggcaactctt
     6721 catagatagg cttgcaacgt ttcaattgct caagactagc tggatagtag tcaatacgtt
     6781 gaccgtcaag atcataggcc acacagattt tcacagtatc caaaccgctc aaaacatcaa
     6841 tagagttcaa agaaaggtta gtaataccag aaacacgacg gctatgacgc atcacaactg
     6901 agtcaaacca acctacacga cgtggacgac cagttgttgt accatattca tgacccactt
     6961 cacggatacg ttctcccact tcatcaaaca actcagttgg gaaaggacca tctcctacac
     7021 gactcgtata agctttacat acacctacaa ccttgtcaat cttgcttgga ccgacaccag
     7081 aaccaattgt cacaccacca gctacagggt ttgatgacgt aacaaatgga taagtacctt
     7141 ggtcgatatc tagcataaca ccttgtgcac cttcaaaaag cacacgtttg ccattatcaa
     7201 gcgcatcatt caagataaca gatgtatcta tcacgtattt cttgatttgt tgaccatatt
     7261 cgtaatattc ttcaaaaata tcatcgaaaa caatcgcttt actgtcatac aatttttcaa
     7321 aaagacgatt cttttcagca aggttacgtt ctaaacgctc acggaaaata tctttatcta
     7381 aaagatctgc aatacgaatt ccaacacgag cagccttgtc catataagct ggaccaattc
     7441 ccttaattgt cgtaccaatc ttattgtcgc ccttagcttc ttcttgcaag cgatccaact
     7501 cgatatgata aggcaaaata acatgcgcac gatcagaaat acgtaagtta tcagttgtta
     7561 caccttcctc atgaagatag ctcaactctt ttacaagaga tttaggattt acaaccatac
     7621 cattcccaat gacagatatt ttttcaggga agaaaatccc agatggaatc aagtgcaact
     7681 taaatttctt accgtcaatc acaatcgtgt gaccagcatt atcaccacct tggtaacgtg
     7741 caatcacttc tgcattcgct gaaaggaagt ctgtaatctt ccctttacct tcatcacccc
     7801 attgggtacc tacaacaaca actgaagtca taattttgtc tgagccctca ggctcttcct
     7861 ttctcacata catggcagga ctctcacctg caattatatc ttacaattta ttataataaa
     7921 aaatcgcctt tttatcaaga agaaacaata gaaagatttg ctatttccaa ctattaaaaa
     7981 atgatttaga aaaattacta gctatttact attatctttc cataaaagag taaattagtt
     8041 cggaaattta ctaaaattac ctcaacaaga aataaaaccc cgattcatta ccaatttttc
     8101 aagatacaaa cgataagcaa cacgataatg gtaaacgata aaatccctac gacaaccaat
     8161 gccatatctc actaaataat aaattaaaaa tttaaaatga acatgttccc agtcaaaatt
     8221 atcaccaaat gtaggaccat actcttcttc aatactatca tagaaattag ccatctgctc
     8281 ataaattttt tgtaacataa tcaaatactc cttttctttt ttataaactt attctaacaa
     8341 aaaattttac acattcacta tcaattcctg aattgttaaa ataccagcct caacaagata
     8401 aaaataggaa aagttgacaa aatagaaaca aatttgctac ctaaatttca aacgattaaa
     8461 gttctaaaaa gaccgcctta aaacttttgg gtaaatccta ttagaactat aatattttta
     8521 tataggtatt atggttctga ttttctagta taaaaaattc aaactagaat tcttcttaga
     8581 aaaggccgtt ttaagtgcta tcactgttca aaaatgatgg tcgctgaaac ttctatcgtc
     8641 aagaagaatc atcaaattcc ttgtatcatc aaccaaaaga ttgctcagaa gctaattaaa
     8701 aagacttcta tgaccgacat tgatcatcag ttgtctattt caacttcaac tgtcattcgc
     8761 aagaacaatg attttcactt tgagcatgat ttttcgcgtc ttcctgagat tatgtcctag
     8821 gacgttgaaa cagtccgggg agtgactgtt tcaatcggga gatggaaatg agctttattg
     8881 ctcaagactt tgataagctc aatatcataa ctgttcttga gagcagaaca caagccatca
     8941 tccgaaatcc catgaataca aggctatcaa gcgatactga aagctcattc aacaagatag
     9001 tcagaaactg agtgataaac gattttatcg ccctactttt cgtatgcact tgactaataa
     9061 agaaattcta gataaacttt tgagctattc cgaagacttg aaacaccact ataatctcta
     9121 tcagctcttg cttttccacc tctttttcag actctgttta aaaccttcct caaagataaa
     9181 gagaaaatcg tcaacgccct tcaattacct tattccaacg ccaaactgga agccaccaat
     9241 aatctcatca aacttatcaa gcacaatgcc tttggtttta ggaactttga aaacttcaaa
     9301 aaagaaagga cgaaatttgt cctttctaga tcttcgcttt cttcaaccca ctacagttga
     9361 caaagaaccg aaaaatgtct cgcctctaat atagtcaatt gaaacaagag caggataaaa
     9421 aagcc
//
LOCUS       DAVBOD010000073         8994 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 640-05
            SAMEA1012484-rid20186543.denovo.074, whole genome shotgun sequence.
ACCESSION   DAVBOD010000073 DAVBOD010000000
VERSION     DAVBOD010000073.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012484
            Sequence Read Archive: ERR059358
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8994)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8994)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979948.1
            Genome Coverage       :: 595x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:03:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,266
            CDSs (total)                      :: 2,219
            Genes (coding)                    :: 2,091
            CDSs (with protein)               :: 2,091
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 71 of 128
            Pseudo Genes (incomplete)         :: 50 of 128
            Pseudo Genes (internal stop)      :: 33 of 128
            Pseudo Genes (multiple problems)  :: 22 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8994
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012484-rid20186543.denovo.074"
                     /strain="NIG 640-05"
                     /db_xref="taxon:1313"
     gene            complement(358..1965)
                     /locus_tag="VQ862_001922"
     CDS             complement(358..1965)
                     /locus_tag="VQ862_001922"
                     /EC_number="6.3.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000105234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CTP synthase"
                     /protein_id="HET3116214.1"
                     /translation="MSTKYIFVTGGVVSSIGKGIVAASLGRLLKNRGLKVTIQKFDPY
                     INIDPGTMSPYQHGEVFVTDDGAETDLDLGHYERFIDINLNKYSNVTTGKIYSEVLRK
                     ERRGEYLGATVQVIPHITDALKEKIKRAALTTDSDVIITEVGGTVGDIESLPFLEALR
                     QMKADVGADNVMYIHTTLLPYLKAAGEMKTKPTQHSVKELRGLGIQPNMLVIRTEEPA
                     GQGIKNKLAQFCDVAPEAVIESLDVEHLYQIPLNLQAQGMDQIVCDHLKLDAPAADMT
                     EWSAMVDKVMNLKKQVKISLVGKYVELQDAYISVVEALKHSGYVNDVEVKINWVNAND
                     VTAENVAELLSDADGIIVPGGFGQRGTEGKIQAIRYARENDVPMLGVCLGMQLTCIEF
                     ARHVLGLEGANSAELAPETKYPIIDIMRDQIDIEDMGGTLRLGLYPSKLKRGSKAAAA
                     YHNQEVVQRRHRHRYEFNNAFREQFEAAGFVFSGVSPDNRLVEIVEIPENKFFVACQY
                     HPELSSRPNRPEELYTAFVTAAVENSN"
     gene            complement(2355..2942)
                     /locus_tag="VQ862_001923"
     CDS             complement(2355..2942)
                     /locus_tag="VQ862_001923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit delta"
                     /protein_id="HET3116215.1"
                     /translation="MELEVFAGQEKSELSMIEVARAILELRGRDHEMHFSDLVNEIQN
                     YLGTSNSDIREALPLFYTELNFDGSFISLGDNKWGLRSWYGVDEIDEEIIALEENDDD
                     EVAPKAKKKRVNAFMDGDSDAIDYNADDPEDEDAYEADPALSYDDENPDDEKNEVEAY
                     DAEINEIAPDDLGEDVDLNEDDDEFSDDDAETSEE"
     gene            complement(3070..3519)
                     /locus_tag="VQ862_001924"
     CDS             complement(3070..3519)
                     /locus_tag="VQ862_001924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000333655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET3116216.1"
                     /translation="MCFVPYYKVNYCEEAFAWYQDVNLVYLVDGVKLPYSQATLEAMY
                     SYLDRHGELFWIEVKEKGEWFPIGDITLSQDNLPIVIGNSAYQHRGLGKKILSALIEL
                     ARVKGWKELRVKEIYTYNHASRRCFKSLGFVENGATEKGRSFILELV"
     gene            complement(3524..3913)
                     /locus_tag="VQ862_001925"
     CDS             complement(3524..3913)
                     /locus_tag="VQ862_001925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000867286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome partitioning protein ParB"
                     /protein_id="HET3116217.1"
                     /translation="MKVNIADLHPTQLYLSEKKLQDIQMLYQSAETIQVDPISILAFG
                     DCLLITDGHHRAYQALLAGRDTISAEWDRDGGDELYHLYAQACEERKIYSVFDLEDRI
                     LAQDGYEAKWYNWCDGFNQAATLLLKR"
     gene            complement(3941..4567)
                     /locus_tag="VQ862_001926"
     CDS             complement(3941..4567)
                     /locus_tag="VQ862_001926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001853067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HET3116218.1"
                     /translation="MKGSFALLLFVILGYMVKFYPEMLVNFDQSIQTAIRGDLPDYLT
                     ILFRSLTRLIDIPVIITWVVITAFVFYRKRWKIESFFMLGNLALAGLLIVTFKNIYQR
                     PRPAILHLVEEKGFSFPSGHSLAVTLMVGTLIVILSQRIKDPVWRKIVQIVLGLYLVS
                     VLVSRVYLGVHYPSDVLASLCVGLGVLFIEFPFYDKLRFQWRFKGKQK"
     gene            complement(4581..5144)
                     /locus_tag="VQ862_001927"
     CDS             complement(4581..5144)
                     /locus_tag="VQ862_001927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HET3116219.1"
                     /translation="MTNTRRLSTIAILSAISFVLMYFDFPLLPAASFLKIEFSILPVL
                     VGLVVMDLPAALGVLLLRSLLKLLLNSQGVNTYIGLPMNIVALGVFVIVFALIWKKER
                     TTLRFLLGSLAGTVGLTLAMLVLNYVYAVPLYAKFANFDIGKILGLSNYLMTMVLPFN
                     LIEGVIFSVSFWLLYVLLKPTLKHYER"
     regulatory      complement(5309..5543)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            complement(5597..6100)
                     /locus_tag="VQ862_001928"
     CDS             complement(5597..6100)
                     /locus_tag="VQ862_001928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000181367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (cytidine(34)-2'-O)-methyltransferase"
                     /protein_id="HET3116220.1"
                     /translation="MTNHIVLFEPQIPQNTGNIARTCAATNSPLHIIKPMGFPIDDRK
                     MKRAGLDYWDKLEIYFYESLEDFISQMKGKLYLISKFAEKVYSEVDLSTDEDHYFLFG
                     REDKGLPEDFMREHPEKALRIPMNDEHVRSLNVSNTVCMIVYEALRQQNFAGLELVHT
                     YEVDKLK"
     gene            complement(6293..7123)
                     /locus_tag="VQ862_001929"
     CDS             complement(6293..7123)
                     /locus_tag="VQ862_001929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HET3116221.1"
                     /translation="MQAKLIGYQHRDTVIHRLSGAGKLLFFILVSLAAMISYDTRMLL
                     LIAIFSVFLLYLSEIRFKDVSFVAVFATVFAVLNVLMVYLFSPEYGVGLYGERSVIWQ
                     GIGVYTLTSQELFYLLNLAIKYLCTIPLAIIFLMTTHPSQFASSLNQIGVPYKIAYSV
                     SLTLRYIPDLQEEFFTIKMSQEARGMELSKKASLMQRIKGNLLIITPLIFSSLERIDT
                     IATAMELRRFGKEKKRTWYSYQALKKGDYITLLLATLFLVVSLLLILQNQGRFYNPWK
                     "
     gene            complement(7108..8790)
                     /locus_tag="VQ862_001930"
     CDS             complement(7108..8790)
                     /locus_tag="VQ862_001930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000656554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3116222.1"
                     /translation="MKEAIIEWKDFSFRYETQQEPTLQGIDLTIYKGEKVLIVGPSGS
                     GKSTLGQCLNGIIPNIYKGQTYGEFLIKGQVAFDMSIYDKSHLVSTVLQDTDGQFIGL
                     SVAEDLAFALENDVTALDEMKGRVYKWAEKLDLLPLLDQRPQDLSGGQKQRVSLAGVL
                     IDESPILLFDEPLANLDPKSGQDIIELIDQIHKEEGTTTLIIEHRLEDVLHRPVDRIV
                     LINDGRILFNGSPDQLLATDLLTQNGIREPLYLTTLRQLGVDLVKEEQLADLDNLSIS
                     KGQVQLQTELVKETSELQSLFRLEEVSFSYDDRPILKSLHLDIKKGEKIAIVGKNGAG
                     KSTLAKAISSFIQTEGRYLWEKQDIKGDSVAERAERVGYVLQNPNQMISTNMIFDEVA
                     LGLRLRGVDEKEIETRVYETLKICGLYEFRNWPISALSFGQKKRVTIASILVLGAEII
                     LLDEPTAGQDQKNYTEIMEFLEELHQKGHTIVMITHDMQLMLDYSDRVLVMVDGELIA
                     DTVPASLLSDPELLVKANLKETSIFNLAKKLDVDPLDLTAFYKERREGCKLN"
BASE COUNT         2722 a         2058 c         1637 g         2577 t
ORIGIN      
        1 tggattaaat taaaaaagta taatgtattg aatctataac agtacatctt gactgctaaa
       61 atatttctat aaattaattt gacttttctg atagagatgt tcacatctta tttcaattca
      121 ctatacaatc cagttcctaa aactttgcta gaaattgatt tggctttccg aattaatttg
      181 ttcaaatttt atttcatttc aatatactga taaatccatt cactagcaca gggcaagagg
      241 gagtcgctat tgatttcaac ggtagcaggt acatacagag gactcctacc tcagatatac
      301 tgcaatatca tcgtatgcaa aaaacctctg agatttttct caaaggttct gattttgcta
      361 attgctgttc tcaaccgctg cagtaacaaa ggcagtgtag agttcttctg gtcggtttgg
      421 acggcttgac agttcagggt gatactgaca agctacaaag aatttatttt caggaatttc
      481 cacgatttct accaaacgat tgtctggaga aactcctgaa aagacaaaac ctgctgcctc
      541 aaactgctca cggaaggcat tattaaactc ataacggtga cggtgacggc gttgcaccac
      601 ttcttgattg tgataagcag cagcagcctt agagccacgt ttcaacttag acggataaag
      661 tcccaaacga agggttccac ccatatcctc aatatcaatc tgatcacgca tgatatcaat
      721 gatagggtat tttgtttctg gtgcaagctc tgcagaattg gcaccttcaa gacctaaaac
      781 gtgacgagca aactcgatac atgtcaactg cattcccaag cagactccca acattggaac
      841 atcattttca cgcgcatagc ggatggcttg gattttccct tctgtaccac gttgaccaaa
      901 accacctggt acgatgatcc cgtccgcatc agacaagagt tctgctacat tctctgctgt
      961 cacatcattg gcattgaccc aattgatttt aacttctaca tcattgacat agccagagtg
     1021 tttcaaggct tcgaccactg agatataggc atcttgcaac tccacatact taccaacaag
     1081 ggaaatctta acttgtttct tgaggttcat gaccttgtcc accatggctg accattctgt
     1141 catatccgct gctggtgcgt ctaatttcaa atgatcacaa acaatttggt ccatcccttg
     1201 tgcctgcaag ttcagtggaa tttggtaaag gtgttcaaca tccaacgatt cgataacggc
     1261 ttctggtgcc acatcacaga actgggccag tttattttta attccttgac cagctggctc
     1321 ttctgtacga ataaccaaca tatttggttg gattcccaag ccacgcaatt ctttgacaga
     1381 gtgttgggtt ggtttggttt tcatttcacc agcagccttg aggtaaggaa gcaaggttgt
     1441 atggatatac atgacattat ccgcacccac atctgccttc atctgacgaa gagcctctag
     1501 gaatggcaag gactcgatat ctcctactgt tccaccaacc tctgtgataa tgacatcaga
     1561 gtcggtcgtt agagcggcac gcttgatttt ttctttcaaa gcatctgtga tatgaggaat
     1621 gacttgaaca gttgccccaa ggtattctcc acggcgttct ttacgaagaa cttcactgta
     1681 aattttccca gttgtcacgt tggaatattt gttgagattg atatcgatga aacgttcata
     1741 gtgacccaag tccaaatctg tctcagctcc gtcatctgtc acaaaaactt ccccgtgctg
     1801 gtaaggactc atggttcccg gatcaatatt gatataaggg tcaaactttt gaatggttac
     1861 tttgagacca cgatttttca agagacggcc tagactcgct gccacaatcc ctttcccaat
     1921 ggacgatacc acaccaccag ttacaaaaat atatttcgta gacatagatt cctctttcta
     1981 aaatgctcaa ggtcttgtta actacgaggg gatatagaaa acaagaccct actaataaga
     2041 ataatctggg acgactgcac cagattcaca actaatactc ttcgaaaatc tcttcaaacc
     2101 gcgtcaacgt cgccttgccg tagatatgtg ttcctgactt tgtcagtctt atctacaacc
     2161 tcaaaacagt gttttgagca gcctacggct agtttcctag cttgctcttt gattttcatt
     2221 gagtataaaa tacaagaaga taacttcttg aaaaaacaaa aatagctccc taagaactag
     2281 ggagccccga cctctaaaag aggtgcccaa acaatatgat acctaaaaat aggataattg
     2341 tcaatagcta actcttattc ctcgctggtt tcagcgtcgt catctgaaaa ctcgtcgtcg
     2401 tcttcgttga gatccacatc ttctcccaag tcatctggag cgatttcgtt gatttctgca
     2461 tcataagctt ccacttcatt tttttcatca tctggatttt catcatcgta tgaaagagct
     2521 ggatctgctt cgtatgcatc ttcgtcttct ggatcatctg cattgtagtc aatggcatct
     2581 gaatcaccat ccataaaggc attgacacgt tttttcttag cttttggtgc tacttcatcg
     2641 tcgtcatttt cttcaagagc gatgatttct tcgtcgattt cgtccacacc ataccatgaa
     2701 cgaagacccc atttgttgtc cccaagtgag atgaagctac cgtcaaagtt caactctgtg
     2761 tagaacaaag gcaaagcttc gcggatatcg ctgtttgatg ttccaaggta gttttgaatt
     2821 tcgtttacaa gatcgctaaa atgcatctca tgatcgcgac cacgaagttc caagatagca
     2881 cgcgctacct caatcataga tagttcactt ttttcttgcc cagcaaatac ttctaattcc
     2941 aaagcgtttc tcctcattta tactactatc gccagagcga acagactctg acctcatttt
     3001 atcatttact ctttatttta cgataatttt gcggaatagt caaaggttaa gggggagaaa
     3061 gtggcaggat tagactaatt ccaatataaa actccttcct ttttctgttg ctccattttc
     3121 cacaaatcca agcgacttga aacacctcct agaagcatga ttgtaggtgt agatttcctt
     3181 gactctcaat tctttccatc cttttactcg agccaattca atcaaagcac ttagaatctt
     3241 ttttccaagt cctcgatgtt ggtaagcgga attcccaatc acaatgggga gattatcctg
     3301 agatagtgta atatccccaa ttggaaacca ttctcccttc tccttgactt caatccaaaa
     3361 aagctcacca tgccgatcca aataggaata catggcttcc aaggtcgctt gactgtaagg
     3421 aagcttcacc ccatctacga ggtaaaccaa gttcacatcc tgataccaag caaaagcttc
     3481 ctcacaataa ttgaccttat aataaggaac aaaacacaat gcactacctt ttcaacaaaa
     3541 gagttgctgc ttgattaaaa ccatcacacc agttatacca ttttgcttca tacccatctt
     3601 gagctaggat acgatcttct aaatcaaaaa cagagtaaat ctttctttcc tcgcaagctt
     3661 gcgcatagag atgatatagt tcatcaccac catctctatc ccactcagca gaaatcgtat
     3721 cccgacctgc caataaagcc tgataagccc tgtgatgccc atctgtaatc agcaaacaat
     3781 ctccaaaggc aagaatactg attggatcga cttggattgt ttctgccgac tggtaaagca
     3841 tctgaatatc ttgcaacttc ttttctgata aatatagttg agtcggatga agatctgcta
     3901 tattgacttt catttctttc tcctcaaggg aattcgatac tcacttctgt ttgcctttaa
     3961 atcgccattg gaagcggagc ttgtcataga agggaaactc gataaacagg actcccaagc
     4021 ccacacagag actggcaagg acgtctgatg ggtaatgaac tcccagatag actcttgata
     4081 ccagcacact gactaggtag aggccaagga cgatttgtac gatttttctc cagactggat
     4141 ctttaatccg ctgactaaga ataacaatca aagtacctac catcaaggtt acagccagag
     4201 aatgcccact tgggaaggaa aatcccttct cctccaccag atgtaagata gctggtcgtg
     4261 ggcgctggta gatattttta aaggtcacga ttaaaagacc tgccaaagcc agatttccca
     4321 gcatgaagaa actttctatc ttccatcgct tacgataaaa gacaaaagct gtaatgacaa
     4381 cccaagtgat aatcactggg atatcaatca gacgtgtgag ggatcgaaaa agaatagtca
     4441 aataatctgg taagtctcct cgaatggcag tctgaatcga ttggtcaaaa ttgaccaaca
     4501 tttcagggta aaatttgacc atatagccaa gaataacgaa aagtaaaagg gcaaaactgc
     4561 ccttcattaa aaatgtttgt ttatctttca tagtgtttta aggttggttt caaaaggacg
     4621 tacaacaacc agaatgaaac ggaaaagatt acaccctcaa tcaagttaaa aggtaatacc
     4681 atggtcatta ggtagttgga aagtcccaaa atttttccaa tatcaaagtt agcaaactta
     4741 gcgtacaaag gaacagcata aacatagttg agaaccaaca tggccaaggt taaaccaaca
     4801 gttccagcta gagagcctag taggaaacga agggttgtcc gttccttttt ccaaatcaaa
     4861 gcaaatacga tgacaaaaac tcccaaagct acgatattca tcggcaaacc aatgtaagta
     4921 ttcactcctt ggctgttaag aagcaatttc aatagtgagc gaagcaagag cactcctaga
     4981 gcagcaggca aatccatgac caccagaccc acaaggactg gcaagatact aaattcgatc
     5041 ttgaggaaag atgccgctgg taaaagcgga aagtcaaagt acatcagcac aaatgagatg
     5101 gctgataaaa ttgcaatggt cgaaagtcga cgtgtgtttg tcataacagg ttcctccaat
     5161 tttctataaa atcagaagaa gttggaaagg attcctctat ctattctcac tttttatatc
     5221 ccaaaagttc cctcttactc tattaaagaa aaacaaagca agtggttaca atccggctat
     5281 aaatctatca aaacagacaa agctattctt tcgtcttctc ccatccagac tatactgtcg
     5341 gttgtggaat ctcaccacat cagcttgcgc tcgcggactt ctttaaagag aaggaaatag
     5401 agatttttct tttagactag gcgacaagct gtaggcataa cttctggtta ggcaaagctt
     5461 gtcaacaaag tataaaagga aaagatcatt tcctagttaa agtcaccgcc ggtcgggaat
     5521 cacaccctgc cctgaagact cttttatcat aacaaaaaac gcttgcaagc gcaagcattt
     5581 tgttcatttt cattttttat ttcaatttat ccacttcata ggtatggacg agctcaagac
     5641 ctgcaaagtt ctgctggcga agagcctcat agacaatcat gcagacggta ttagacacat
     5701 tgagactgcg gacatgttca tcattcatgg gaatacggag agccttctca ggatgttctc
     5761 gcataaaatc ttcaggtaag cccttgtctt cacgtccaaa gagaaaataa tggtcctcgt
     5821 cagtcgataa atccacctca gaatagactt tttccgcgaa tttcgaaatc agatagagtt
     5881 ttcccttcat ctgagatatg aaatcttcca aactctcgta aaaataaatc tctagcttat
     5941 cccagtaatc caatccagcc cgcttcatct tgcggtcatc aataggaaag cccataggct
     6001 tgatgatgtg gaggggagaa ttggtcgcag cgcaagtacg cgcgatattg cccgtatttt
     6061 gtggaatttg aggttcaaat aatacaatgt gatttgtcat gacttgcttc ctttcaccat
     6121 tgcaaaaaaa tagccacact gcccggagtc aagctcagca aacagcgtgg ttaaggcatc
     6181 gttaacttac ctcacaacag gtttgaagta aatcagcgaa actactttct tagtataaca
     6241 ctttcagaat cattgtcaat agaaatgact tgattttttc aattttttca agctatttcc
     6301 aagggttgta aaatcgtccc tgattctgca agataagtag taaactaact actaaaaaca
     6361 aggttgccaa gagcaaggta atatagtctc cttttttcaa ggcctgataa ctataccatg
     6421 tgcgtttttt ctctttccca aagcggcgaa gctccatggc agtcgcaatg gtatcaatgc
     6481 gttctagcga gctaaaaatc aagggcgtaa taatgagcag attgcctttg attcgttgca
     6541 taagagaagc tttcttggat aattccatcc cacgcgcctc ctgagacatc ttgatagtaa
     6601 agaattcttc ctgcaaatct ggaatatagc gcaaggtcag gctgacagaa taagcaatct
     6661 tatagggcac accaatttga tttaaactgg aagcaaactg actaggatgg gttgtcatca
     6721 aaaagataat agccagagga atggtgcaaa gatacttaat ggccaaattt agcagataaa
     6781 agagctcctg gctggttaga gtgtagacac cgattccctg ccaaatcaca cttctctctc
     6841 cataaagtcc aaccccatac tcgggagaaa agagatagac catcaaaacg tttaaaacgg
     6901 caaataccgt cgcaaaaacg gctacaaagg aaacatcttt aaagcgaatt tctgataaat
     6961 agaggagaaa gactgaaaag atggcaatca gcaagagcat tctggtatca tagctaatca
     7021 tggccgccaa tgataccaga atgaaaaaga gaagtttccc agctcctgac aagcgatgaa
     7081 tcacagtatc tctatgctgg taaccgatta atttagcttg catccctctc tcctttcttt
     7141 gtaaaatgcc gttaaatcca gtggatccac atctagtttc ttagccaagt taaagatgga
     7201 ggtttctttt agattggctt ttactaacag ctcaggatcg ctcaacagac tggctggaac
     7261 agtatcggca atcaattctc catccaccat gacaaggacc cggtctgaat aatccagcat
     7321 caattgcata tcatgggtaa tcatgacaat ggtatgccct ttttgatgta actcttcgag
     7381 aaattccata atctcagtat agttcttctg atcttgacct gcagtcggtt catctaggag
     7441 aataatttca gctcctaaga ccaaaattga agcaatggtg acacgttttt tctgaccaaa
     7501 tgacagggca gaaataggcc aattacggaa ttcataaagt ccacagattt tcaaggtttc
     7561 atagactctc gtttcaattt ccttctcatc cacacctcgc aaacggagcc ctagagccac
     7621 ctcatcaaaa atcatattgg ttgaaatcat ttgattagga ttttgtagca catatcctac
     7681 tcgttccgcc cgctctgcaa cagaatcgcc ttttatatcc tgtttttccc aaagatagcg
     7741 tccttccgtc tgaataaagc tacttatagc cttggctaga gttgatttcc ctgctccatt
     7801 ttttccgaca atagcaatct tttcaccctt tttaatatct aaatgtaggg attttaaaat
     7861 cggtctatca tcataagaaa aagatacttc ctctagtcta aagagtgact gcaattctga
     7921 ggtttctttt accagttccg tctgtaactg gacttgccct tttgagatag acaagttatc
     7981 cagatctgct aattgttctt ccttgactaa gtccacacct aattgacgga gagtggttag
     8041 ataaaggggt tctcgaattc cattttgagt caataaatca gtcgcaagca actggtcagg
     8101 gctcccatta aaaaggatac gaccatcgtt tatcaagaca atccgatcca cagggcgatg
     8161 cagaacgtcc tccaaacggt gctcgataat cagagtcgtc gtcccctctt ccttatgaat
     8221 ctggtcaatc aattcgataa tatcctgacc tgacttggga tctagattgg cgagtggctc
     8281 atcaaacaag agaatcggac tttcatcaat caagacacca gccagactga ctcgctgctt
     8341 ttgtccacct gacaaatcct gaggacgctg atccagtaaa ggaagaaggt ccagcttttc
     8401 agcccattta taaacacgac ctttcatctc atctagggct gtcacatcat tttccagagc
     8461 aaacgccaaa tcttctgcca cagacaagcc aataaactgc ccatctgtat cctgcaaaac
     8521 tgtgctaacc agatgagact tatcatagat gctcatatca aaggctactt gaccctttat
     8581 caaaaattct ccatatgtct gacccttgta aatattggga ataatcccat tcaaacactg
     8641 acccaaggta gatttacctg acccagatgg tccaacaatt aagactttct ctcccttgta
     8701 aatggtcaag tctatccctt gcaaggtcgg ttcttgttgt gtttcatacc ggaaagagaa
     8761 atccttccac tcaattatag cttctttcat cttactctct tcattcgctt cttagacttc
     8821 tattttatca taaatcaagc ccttcttgca gtctcttctc ttaaaatctt agcgccaaaa
     8881 agattcctat cctagcttac ttgcctaact aatctataaa catcgaaaaa gactagttgc
     8941 ccagccttcc ccatcatttt atactcttcg aaaatctctt caaaccacgt cagc
//
LOCUS       DAVBOD010000074         8327 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 640-05
            SAMEA1012484-rid20186543.denovo.075, whole genome shotgun sequence.
ACCESSION   DAVBOD010000074 DAVBOD010000000
VERSION     DAVBOD010000074.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012484
            Sequence Read Archive: ERR059358
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8327)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8327)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979948.1
            Genome Coverage       :: 595x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:03:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,266
            CDSs (total)                      :: 2,219
            Genes (coding)                    :: 2,091
            CDSs (with protein)               :: 2,091
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 71 of 128
            Pseudo Genes (incomplete)         :: 50 of 128
            Pseudo Genes (internal stop)      :: 33 of 128
            Pseudo Genes (multiple problems)  :: 22 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8327
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012484-rid20186543.denovo.075"
                     /strain="NIG 640-05"
                     /db_xref="taxon:1313"
     gene            complement(549..857)
                     /locus_tag="VQ862_001931"
     CDS             complement(549..857)
                     /locus_tag="VQ862_001931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000134125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HET3116223.1"
                     /translation="MTEEMEYICFQLIANSGAAKSSFIEAIQLAKAGNLKEAKIKVEE
                     AEDSLVEAHKIHSNLIQKEATGEKIGFSLLFMHAEDQMASTEIIQLLSKEFIDLYQNK
                     "
     gene            complement(854..1162)
                     /locus_tag="VQ862_001932"
     CDS             complement(854..1162)
                     /locus_tag="VQ862_001932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HET3116224.1"
                     /translation="MKQILLVCNAGMSTSMLVKKMQQSATERGIEISIQAKSMTEAKK
                     NIHEADVILIGPQIRYELLAVKEIAGNTPVDTIDMRDYGMMNGAKVLEQALAWIGEIR
                     "
     gene            complement(1167..2462)
                     /locus_tag="VQ862_001933"
     CDS             complement(1167..2462)
                     /locus_tag="VQ862_001933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000798148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HET3116225.1"
                     /translation="MKNSKFIDQFATFAGKLGNQIHLKTLRDAFVTVMPLYILAGLIV
                     LLNNTVFKWIFQGDTLTKFQYWGITIANGTLSISGMIIAVMVGYFLAKNRDFENPLAA
                     SMLSLVSLIVMMPNTVSVVPDGAKDAVNISGVLSFNNTGTGAMFAGVIVAIIATELFI
                     ELSNVKALQMNLGENIPPAVSRSFSVLLPVMTAISLFGVVSALLFNITGMNLISIITI
                     FIQEPIRHIGTSLIGVIIIYSLGNMLWLFGIHQAVIYSAILEPLLLINITENITAANN
                     GQAIPHIINLSQIQTFALMGGSGSTLCLLIATFLVSRNAVSKNVAKLSFGPGIFNINE
                     PVLFGYPIVYNISLAIPFITVPVLGILISYLATVTGFMSPAFIQVPWTTPVFLNAWLA
                     TAGDVRAVLVQFIIFALGVLLYIPFIKVNDKVVEQEMEG"
     gene            complement(2480..3889)
                     /locus_tag="VQ862_001934"
     CDS             complement(2480..3889)
                     /locus_tag="VQ862_001934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000728302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HET3116226.1"
                     /translation="MKKKLVFPNLFWWGAASSGPQTEGQYGKVHENVMDYWFKTHPED
                     FFDNVGPLVASNFFHTYTEDFHLMKEIGVNSFRTSIQWSRLIKNLETGEPDPKGIAFY
                     NAIIEEAKKNQMDLVMNLHHFDLPVELLQKYGGWESKHVVELFVKFAKTAFTCFGDKV
                     HYWTTFNEPMVIPEAGYLYAFHYPNLKGKGKEAVQVIYNLNLASAKVIQLYRSLGLDG
                     KIGIILNLTPAYPRSNSPEDLEASRFTEDFFNKVFLNPAVKGTFPERLVKQLERDGVL
                     WSHTEKELQLMKSNTVDFLGVNYYHPKRVQAQANPEEYQTPWMPDQYFKEYEWPERRM
                     NPYRGWEIFPKAIYDIAMIVKEEYDNIPWFISENGMGVENEARFIDENGVIDDVYRIE
                     FYEEHLRWLHKAIEEGSHCFGYHAWTAFDCWSWNNAYKNRYGFISVDLETQKRTIKSS
                     GRWYRKVSDNNGFEVEIEE"
     gene            4047..4775
                     /locus_tag="VQ862_001935"
     CDS             4047..4775
                     /locus_tag="VQ862_001935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000105270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HET3116227.1"
                     /translation="MSTKYLFIYNEIREKILCNKYTMNEQLPDEMTLAKQFACSRMTI
                     KKALDLLVSEGLIFRKRGQGTFVLSRGSSKRKLIVPERDIRGLTKISEDAHSTIDSRI
                     IHFKLEFANEFLAEKLQVALQSPVYNIYRLRIIDGKPYVLEQTYMSTDVIPGITEDIL
                     QKSIYNYIEGKLGLHIASATKILRASSSSENEQHYLQLLPTEPVFEVEQVAYLDNGTP
                     FEYSISRHRYDLFEFNSFALRHSS"
     gene            5234..5428
                     /locus_tag="VQ862_001936"
     CDS             5234..5428
                     /locus_tag="VQ862_001936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HET3116228.1"
                     /translation="MKGKEYENRTVSFAISSKGEKMKVENISYRVDHRILFDNISFDT
                     SSSGVTLITGKNGTGKSTLL"
     gene            complement(5793..7103)
                     /locus_tag="VQ862_001937"
     CDS             complement(5793..7103)
                     /locus_tag="VQ862_001937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000581523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SLC13 family permease"
                     /protein_id="HET3116229.1"
                     /translation="MIHLIMISAIALAIGIGYRTKINIGLLAIAFSYLIATTLMGLSP
                     KELLHFWPTSLFFTIFSVSLFYNVATTNGTLDVLAQHILYRTRTHPNALYMILYLMAT
                     LLSALGAGFFTTMAVCCPLAITLCQKADKHPLIGAQAVNWGASGGANLITSSSGIVFQ
                     GLFKQMGWEEQAFSLGNHIFIVSIIYPLIVLLLLSCYSHYSKGRTNSSLTIDQPPLLS
                     KVQRQTTLLMISSMVLVWLFPLLHLIFPNIAWIATYQKTFDIGFVSILMVCLALRLKL
                     GKQEAILAKVPWATIIMLCGMSLLMSLAVKSGLVTLIGHLMTTTIPHFWLPLFFCVIA
                     GVMSLFSSTLSVVAPALFPIIAIISAQNPQIDIHLLTTATVIGALSTNISPFSSAGSL
                     IQLSLPNIEERGLAFKKQIILGVPISLSLGLLTTWILILLASLS"
     gene            7340..8212
                     /locus_tag="VQ862_001938"
     CDS             7340..8212
                     /locus_tag="VQ862_001938"
                     /EC_number="2.4.2.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxylating nicotinate-nucleotide
                     diphosphorylase"
                     /protein_id="HET3116230.1"
                     /translation="MSIISTDLTPFQIDDTLKAALREDVHSEDYSTNAIFDHHGQAKV
                     SLFAKEAGVLAGLTVFQRVFTLFDAEVTFQNPHQFKDGDRLTSGDLVLEIIGSVRSLL
                     TCERVALNFLQHLSGIASMTAAYVEALGDDCIKVFDTRKTTPNLRLFEKYAVRVGGGY
                     NHRFNLSDAILLKDNHIAAVGSVQKAIAQARAYAPFVKMVEVEVESLAAAEEAAAAGA
                     DIIMLDNMSLEQIEQAITLIAGRSRIECSGNIDMTTISRFRGLAIDYVSSGSLTHSAK
                     SLDFSMKGLTYLDV"
BASE COUNT         2588 a         1457 c         1584 g         2698 t
ORIGIN      
        1 gatagagttg ttcacatctt atttcaattc actatagttt aatttaagag tagtatttac
       61 taaggcccaa ttaaaatcaa agagcaaacg agaaaacgat gacaaggtgt gttgcttttt
      121 gatttctaaa gagtataatg atagatctct ataaaataag tgcgaaggaa atgagctttt
      181 ataatccttt cgttttaaaa tactatctca gatattctta tatcgacaag aagtttttga
      241 gtcattccct catcatacat attaaataaa tagtggctca ttcaattttt cactagaata
      301 ataagctagt atagtaaact gaaataagat ataaacaaat aaattggagc ttaacatcta
      361 tttccagcaa ttttttagaa attgcagtgg actattctag attcaataca ttataaaaac
      421 tagagtaaaa gaaaaggatt ggatcttgtg taatgcagga tccaatcctt tcaatcattt
      481 tgtccaactt ttggaggttc ctacaatgta gccgtcatta ataaagacag atgggaacga
      541 cagtgttcct atttattttg atagagatcg atgaattctt tagatagcaa ctgaataatc
      601 tctgttgaag ccatttggtc ttctgcatgc ataaatagca aggagaatcc tattttttct
      661 ccagtagctt ctttttgtat gagattagag tgaatcttgt gcgcttctac taaggagtct
      721 tccgcttctt caactttaat tttcgcttct tttaaatttc ccgccttagc tagttggatg
      781 gcttcaataa aggatgattt ggctgctcca ctattggcaa tgagctgaaa acagatatat
      841 tccatttctt ctgtcatctt atttctccta tccatgcaag tgcttgttcc agaacttttg
      901 ctccattcat cattccgtaa tcccgcatat caatggtatc tacaggggta tttcctgcaa
      961 tttctttcac agcaagtaac tcataacgaa tttgtggccc aattagaatg acatctgctt
     1021 catggatatt ctttttagct tctgtcattg attttgcttg gatagaaatt tcaatcccac
     1081 gttcagtcgc actttgttgc atttttttaa caagcatact tgtcgacatt cccgcattac
     1141 atactaataa aatttgtttc ataatcttaa ccttccattt cttgttcaac aactttgtca
     1201 ttaactttga taaatggaat gtatagaaga actccaagtg caaagatgat gaattgaact
     1261 agaactgctc tcacgtcccc tgctgttgct aaccatgcat ttaagaatac tggtgtagtc
     1321 caaggaactt gtataaatgc aggactcatg aatcctgtaa ctgttgctaa gtagctgatt
     1381 aaaataccaa ggactggaac tgtgataaat ggaatagcta atgaaatgtt ataaacgatt
     1441 gggtaaccga ataatactgg ttcattgata ttgaagatac caggtccaaa agataattta
     1501 gccacgtttt tagaaacagc attgcgactc actaagaatg ttgctattaa taaacataat
     1561 gtagatccac taccacccat taaagcgaat gtttgtattt gtgataagtt gatgatgtgt
     1621 ggaatggctt gtccattatt tgctgcagtg atgttttcag taatgttaat taatagtaat
     1681 ggttctagga tggcactgta aataactgct tggtgaatac caaatagcca taacatattt
     1741 cctaaagagt aaataataat gaccccgatt aagcttgtac caatatgacg aattggttct
     1801 tgaataaaga ttgtaatgat tgagattaag ttcattccag ttatattgaa taataatgct
     1861 gaaacaaccc caaataagga gatggcggtc atgactggaa gtaatacgct aaatgatcta
     1921 ctaacagctg gtggaatatt ttcaccaagg ttcatttgta aagctttaac gtttgataat
     1981 tcaatgaata attctgttgc aataatcgct acgataaccc cggcgaacat tgcgcctgta
     2041 cctgtgttgt tgaatgaaag aacacctgaa atgtttaccg catcttttgc tccgtcagga
     2101 actacagaaa ctgtatttgg catcatcaca attaaagaaa ctaatgatag cattgatgct
     2161 gctaacgggt tttcgaaatc tctgttttta gctaagaaat aaccaaccat tacagcaata
     2221 atcatacctg aaatacttaa agtaccgttt gcaattgtta ttccccaata ttggaatttt
     2281 gttaatgtat ccccttggaa aatccactta aataccgtgt tgttcaaaag aacgattaaa
     2341 cctgccaaaa tatataatgg cattactgtt acgaatgcat ctcttagggt ttttaaatga
     2401 atttggttcc ctagtttacc agcaaaggtg gcaaattgat ctataaattt tgagtttttc
     2461 atctgaatat ctcctctctt tactcctcaa tttctacttc aaaaccgtta ttgtcactta
     2521 ctttgcgata ccatcttcct gagctcttga tggttctctt ttgcgtttct aaatcaacgg
     2581 agataaatcc gtaacgattc ttatatgcat tattccaaga ccagcaatca aatgcggtcc
     2641 aagcgtggta tccaaaacag tgacttccct cttcaatggc tttatgtagc catcttaaat
     2701 gttcttcata aaattcaata cgatacacgt catcgataac tccattttca tcgataaacc
     2761 gtgcttcgtt ttcaacaccc attccgtttt cactgataaa ccatggaata ttatcatatt
     2821 cttccttcac aatcatagca atatcataaa tggctttcgg aaaaatttcc caaccacgat
     2881 atggattcat gcgacgctcc ggccattcat actctttgaa gtattggtct ggcatccagg
     2941 gcgtctgata ttcctcagga tttgcttgtg cttgaacacg ttttggatgg tagtagttta
     3001 ctccaagaaa atcaaccgta tttgatttca tcagttgaag ctctttttcg gtatgactcc
     3061 ataacacgcc atctctctct agctgtttta ccaatctttc tgggaaagtt cctttaacag
     3121 ctggattcaa gaagactttg ttaaagaagt cttctgtaaa tcgacttgct tctaagtctt
     3181 ctggagaatt acttcttgga taagcaggtg tcaagtttaa aataatccca atctttccat
     3241 caagtcctaa tgagcgatat agttgaatca cttttgcact agcaaggttt agattataga
     3301 tgacttgtac ggcctctttt ccctttcctt ttagatttgg ataatggaaa gcatataagt
     3361 atcctgcttc tggaatgacc attggctcat tgaaagttgt ccagtaatga accttatctc
     3421 caaagcatgt gaaagcagtc ttggcaaact tcacgaataa ctccactaca tgtttgcttt
     3481 cccaaccacc gtatttttga agaagttcca ctggtaaatc aaaatgatgt aaattcatca
     3541 caagatccat ctggttcttt ttagcttctt caatgatggc attgtagaaa gcaatacctt
     3601 ttggatcagg ctcacctgtc tctaaattct tgatgagtcg actccattgg atggaagtgc
     3661 ggaaagaatt aactccaatt tccttcatca agtggaaatc ttcggtgtaa gtatgaaaaa
     3721 agttactggc tacaagaggt ccgacattat cgaaaaaatc ttctggatgc gttttgaacc
     3781 agtagtccat cacattttca tgtacttttc catattgacc ttctgtctga ggtccgctag
     3841 aagcagctcc ccaccaaaac agattaggaa atactaactt ttttttcatg ctcaacctcc
     3901 tttctattat tctatacata aagtatagca taattttaaa atttgtctag acatttttaa
     3961 aaattgttga tacatatctt gtgtttgcct catttcttga actttgttat actactatta
     4021 gaatattata gagagaacca gattaaatga gtacaaaata tttatttatt tacaatgaga
     4081 ttcgtgaaaa gattctttgt aataaatata ccatgaacga acaattgcct gatgaaatga
     4141 cattagctaa acagtttgcc tgtagtcgaa tgacgatcaa aaaagcttta gacttgttag
     4201 tttctgaggg cttaattttt agaaaacgtg ggcagggaac ctttgttctc tctcgtggca
     4261 gctcaaaaag aaaattaatc gttccagaaa gagatatccg gggactgaca aaaatatctg
     4321 aagatgctca ttctacaatt gactcgagga ttattcactt caaattagaa tttgcaaatg
     4381 aatttttagc agaaaaacta caggtcgctt tgcagagtcc agtttataat atttaccgtc
     4441 tgcgtattat tgacggtaaa ccttatgttc tggaacaaac ttatatgagt accgatgtta
     4501 ttccaggtat tactgaagat attttacaaa aatcgattta caattacatt gaaggaaagt
     4561 taggattgca tattgccagt gctacaaaaa tcttgcgagc ttcttctagt tcagaaaatg
     4621 agcaacatta cttgcagctc cttccaacgg aaccggtatt tgaagtagaa caagtggctt
     4681 atttggataa cggaactccg tttgagtact cgattagtcg tcatcgctat gatttatttg
     4741 aatttaattc ttttgcatta cgacattcct cctaggagaa aatgtgaaaa tgaagccaat
     4801 cttttacaga ctctagttta agaaaaattt aaaacagggc aagaaggtcc catctatgct
     4861 taaatggttt ctcttttcta aataagatgg ctttaaaaga gtgatcgttt tatccatcat
     4921 gttgaaaaat atcttcgtat agcttataga gtaggtactg aaattgttca cctgatctac
     4981 ttcttatagt tatttagttt taaatagtgt ttcaaacatt cttacactga cgagaagttt
     5041 ttgagtcttt tcttgtaaca catatagtat actgaggtta gaatagtaga ctgtgacttc
     5101 taaaaaattg ctagaaatga atttcaatct cccaatttat ttgttcatat cttcttttaa
     5161 tatattaaat aaattctgaa tcataatcat ttaaaaaaat tttatttttt atttttcatt
     5221 acgaataata tagatgaagg ggaaagagta tgaaaacaga actgtttctt ttgctattag
     5281 ttcaaaagga gaaaaaatga aagtagaaaa tatttcgtat agggtggatc atcgtatatt
     5341 gtttgataat atttcttttg atacttcgag ttcaggcgtg acattaatta ctggtaaaaa
     5401 tggtacagga aagtcaactt tactatagta gattgaaact agaatagtac acatctactt
     5461 ctaaaatatt gttagaaatc gatttgacta tcctgatcta tttgtcctgt tcttatttca
     5521 tttcactata tctcaaattg agtatgacga agtgcgctcc catgtcctgg gaacgcactt
     5581 cgtcatattt ttcatattct tgaatccatc gataaagact attgggatga atttttaaag
     5641 ttgaactaat tatttttaca ggatgaggtt tacagcagag agtttgaagg ctttatcaaa
     5701 ggtttttctt ggcataatga cttttcctcg tttccactta attttgtgtc tactttatta
     5761 taccaagtcc acccttaagt tagataatga atctaactta aggaagctag aaggatgaga
     5821 atccaggtgg tcaagagtcc caaacttaag ctgataggga cacccagaat aatttgcttt
     5881 ttgaaggcaa gaccgcgttc ctctatattg gggagtgaga gttgaatgag agaaccagct
     5941 gatgaaaagg gtgagatatt agtagataga gcgccaataa cggtggctgt tgtgagtaag
     6001 tgaatatcaa tctgaggatt ttgagcactg atgatagcaa tgatgggaaa gagggctgga
     6061 gctacaacgg atagggtgga actaaagagt gacatcactc cggctatcac acaaaagaac
     6121 agaggtaacc agaaatgagg aatggttgtt gtcatgaggt gccctatcag tgtgactaaa
     6181 cctgacttga ccgctagaga cattagtaag ctcatgccgc agagcatgat aattgtagcc
     6241 cagggaactt tagccaaaat ggcttcttgc ttccctaatt tgagccttaa ggcgaggcag
     6301 accatgagta ttgagacaaa gccaatatca aatgtttttt gataagtagc tatccaggcg
     6361 atgtttggga aaatgagatg caacaaggga aaaagccaaa ccaaaaccat gctgctgatc
     6421 atgagcaagg tggtttgtct ttgaaccttg ctgaggagtg gtggttggtc aatagtcaag
     6481 gatgagtttg ttcttccctt actatagtgg ctgtaacagg ataataaaag caagacgatg
     6541 agtgggtaga taatgctgac gataaagata tgattgccaa gtgaaaaagc ttgctcttcc
     6601 catcccattt gcttaaacag gccttgaaag acaatgcctg agctactggt tatcaaatta
     6661 gcccctcctg aagctcccca attgacggct tgagctccaa tcaaagggtg tttgtccgct
     6721 ttttgacaga gggtaatcgc tagaggacag caaacggcca tagtagtgaa aaatccagca
     6781 cctaaagcag acaaaagggt tgccatcagg tataaaatca tgtagagggc gttaggatgg
     6841 gtgcgtgtgc ggtagagaat gtgttgagcc aagacatcaa gagtaccgtt agttgttgca
     6901 acgttataaa agagagagac gctaaaaatg gtaaaaaaga gtgaggttgg ccaaaaatga
     6961 agaagttctt tggggcttaa tcccatgaga gtggttgcga tgaggtaaga aaaagcaata
     7021 gccagcaggc caatattgat tttggtgcgg taaccaattc caatggctag agcaatggcg
     7081 ctaatcatta ttaaatgaat cattgaattg tcctttcagt tagaatatgg aaataggttg
     7141 gcaattttgg cgctcaaaag accacctgtt tcctattggt acttgactat tatacacaaa
     7201 aaaaatacaa ttgtcttgac aattgtattg acacttgtta gaattaaaaa tgaggtattc
     7261 aggcttgtga tttcctatgg aagttcatag tgattgcctc tagtgcttac aagtgatatt
     7321 aaaaatagag gatctagtga tgtcaatcat ttcaactgat ttaacccctt ttcaaataga
     7381 tgatacattg aaagcagcct tgcgagaaga tgttcattcc gaagattaca gtaccaatgc
     7441 catttttgat catcatggcc aagccaaggt gtcgcttttt gccaaggaag ctggtgtttt
     7501 agcggggcta accgtttttc aaagggtttt taccctattt gatgccgagg tgaccttcca
     7561 gaatcctcat caatttaagg atggggatcg tttgactagt ggcgatttgg ttttagaaat
     7621 cataggctcg gtgagaagtc tcttaacatg tgaacgcgtt gccttgaatt ttttacaaca
     7681 tttatcaggg attgcttcga tgacagctgc ttatgtagaa gccttaggcg atgattgcat
     7741 taaggtattt gatactcgaa aaactactcc taatttacgt ctttttgaga aatatgccgt
     7801 gagagttggc ggtggctata atcatcgctt taatttatca gatgctatcc tgctaaaaga
     7861 caatcacatt gcggcagtag gtagtgttca aaaggcaatt gctcaagcgc gtgcctatgc
     7921 cccttttgtg aaaatggtcg aggtggaagt ggaaagcctt gctgctgccg aagaagctgc
     7981 ggcggcgggt gctgatatta tcatgttgga taatatgtca ttggaacaga ttgaacaggc
     8041 cattacccta attgcaggac gttctcggat tgaatgttct ggaaatattg atatgaccac
     8101 tattagccgt tttcgtggtt tagcgattga ttacgtctcc agtggtagtt taacccatag
     8161 tgctaagagt cttgattttt ccatgaaggg gttaacctac cttgatgtct aagttgtaaa
     8221 ataaactaac tttttaaagg atgtctttcc tctagaacga gttttatgtc agatagttta
     8281 aacgcctctt caaatatagt aaaatgaacc aaaaatagta cacaatg
//
LOCUS       DAVBOD010000075         7532 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 640-05
            SAMEA1012484-rid20186543.denovo.076, whole genome shotgun sequence.
ACCESSION   DAVBOD010000075 DAVBOD010000000
VERSION     DAVBOD010000075.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012484
            Sequence Read Archive: ERR059358
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7532)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7532)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979948.1
            Genome Coverage       :: 595x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:03:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,266
            CDSs (total)                      :: 2,219
            Genes (coding)                    :: 2,091
            CDSs (with protein)               :: 2,091
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 71 of 128
            Pseudo Genes (incomplete)         :: 50 of 128
            Pseudo Genes (internal stop)      :: 33 of 128
            Pseudo Genes (multiple problems)  :: 22 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7532
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012484-rid20186543.denovo.076"
                     /strain="NIG 640-05"
                     /db_xref="taxon:1313"
     gene            complement(173..1588)
                     /locus_tag="VQ862_001939"
     CDS             complement(173..1588)
                     /locus_tag="VQ862_001939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HET3116231.1"
                     /translation="MTIFPDDFLWGGAVAANQVEGAYNEDGKGLSVQDVLPKGGLGEA
                     TENPTEDNLKLIGIDFYHKYKEDISLFSEMGFNVFRTSIAWSRIFPKGDEEEPNEAGL
                     KYYDELFDELHAHGIEPLVTLSHYETPLYLARKYHGWIDRRMIHFYEKFARTVLERYK
                     DKVKYWLTFNEVNSVLELPFTSGGIDIPKENLSKQELYQAIHHELVASSLVTKIAREI
                     NSEFKVGCMVLAMPAYPMTPNPKDVWATHEYENLNYLFSDVHVRGYYPNYAKRYFKEN
                     DINIEFAAEDAELLKNYTVDFLSFSYYMSVTQSALPTQYNSGEGNIIGGLVNPYLESS
                     EWGWQIDPIGLRIILNRYYDRYQIPLFIVENGLGAKDQLIKDEFNNLTVQDDYRIQYM
                     KEHLLQVAEALQDGVEIMGYTSWGCIDCVSMSTAQLSKRYGLIYVDRNDDGNGTFNRY
                     KKMSFTWYKGVIESNGESLFK"
     gene            complement(1601..3439)
                     /locus_tag="VQ862_001940"
     CDS             complement(1601..3439)
                     /locus_tag="VQ862_001940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HET3116232.1"
                     /translation="MSYKDKVQKILDVIGGEKNVNRVTHCVTRLRLELKDENLVNDDD
                     VKKIPGVIGIMKKNGQYQIILGNDVANYYKEFVKLGNFESDSVVQGHKGNILERIIEY
                     IAGSMTPIIPAMLGGGMLKVLVIILPMLGILQSDSQTIAFLTFFGDAPYYFLPLLLAY
                     SASQKLKVTSTLAMSVAGVLLHPNFVQMVQSGNPLSLFGVPVIPASYGSSVVPILIMV
                     WLMKYIEKMIAKLTPAVTKSFLQPTLVLLVSSCIALVVVGPIGVIVGEGLSNLVGQMY
                     DVAGWLTLAILGAIMPFIVMTGMHWAFAPIFLAASIATPDVLILPAMLGSNLAQGAAS
                     MAVALKSKNNNTKQIAFAAGFSALLAGITEPALYGVTLKYKKPLYAAMIGGGLAGLFA
                     GLTSVKAYLFAVPSLIALPQFIYSDVPSNIVNALIVAVISVVITFVLAYIFGIDEEES
                     SSNLEVKAGVSNKKMIFSPISGEIIPLSDVQDKTFSDKLIGDGVAIIPSEGKVYAPFD
                     GKITNIFPTKHAIGLKSDEGVELLIHIGLDTVELKGQGFISHVEEGDRVFKNQLIFEM
                     DLNLIKTKGYETVTPVIVTNTNDFLDVLVLPNNQTIEHSKELLVIL"
     gene            complement(3457..4296)
                     /locus_tag="VQ862_001941"
     CDS             complement(3457..4296)
                     /locus_tag="VQ862_001941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HET3116233.1"
                     /translation="MIIKRILNHNAVIAQSKKDIDILLFGRGIAFGRKTGDKVNPIDI
                     EKSFFLKNRDNMTRFTEMFINVPLELVYITEKIINLGKITLGNNFDEIIYINLTDHIS
                     SSIERYKEGVIISNPLRWEISKYYKEEFELGKRALQIIKKELGIELPIDEAAFIALHF
                     VNANLENNFQESYKITEIIMGIEKIIQDFYCTEFNQDSIDYYRFITHIKLFAHRLVEN
                     TTYCDDDDEDLLALMKNKYPREYECGEQVAMFIQTEYNYLLTSSELVYLMAHIRRLTK
                     NLD"
     gene            complement(4597..7276)
                     /locus_tag="VQ862_001942"
                     /pseudo
     CDS             complement(4597..7276)
                     /locus_tag="VQ862_001942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000268095.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
BASE COUNT         2474 a         1580 c         1039 g         2439 t
ORIGIN      
        1 ccaatctatc ctaagttaac tatttataat cggctctctg taacaaaatt aaattaatta
       61 atccccctat aaaataaaga ggtttagaat ttgatgtctt ccaaacctct ttatttcata
      121 tttaatgaga tgctgcctta accgtgataa tatctaatca tcaataaaca aactatttga
      181 ataaggattc tccatttgat tcaatcactc ctttatacca agtaaaggac attttcttat
      241 atcgattgaa tgtgccattt ccatcatcat ttcgatcaac ataaatgaga ccgtacctct
      301 tagaaagctg tgcagtggac atagaaacgc agtcaataca tccccaagac gtatagccca
      361 taatttccac accatcttgt agagcttcag ctacttgcaa taaatgttct ttcatatact
      421 gaattctata atcatcttgg actgttaagt tattaaattc atcttttatt agttgatctt
      481 tagcacctaa tccgttttcc actataaata atggaatttg ataacggtca taatatctat
      541 ttaaaattat acgtagtcca attggatcaa tttgccatcc ccactcagaa gactctaaat
      601 aaggatttac taaaccacca ataatattcc cttctcctga attatactgt gttggaagag
      661 cagattgagt cacactcatg taatagctaa aggataaaaa atctacagta taatttttta
      721 ataactctgc atcttcagct gcaaactcta tgttaatgtc attttcctta aaatatcttt
      781 ttgcataatt cggataataa cctctaacat gcacatctga aaatagataa tttagattct
      841 catactcatg agtcgcccat acatcttttg gatttggagt cattggataa gctggcatag
      901 ctaataccat acaccccacc ttaaactctg aattaatctc acgagcaatt tttgtaacca
      961 aactcgaggc gactaattca tgatgtatag cttgatataa ttcttgtttc gaaagattct
     1021 ccttaggtat atctattcct ccactagtaa acggtaattc caaaacagag tttacttcgt
     1081 taaatgtaag ccaatattta actttatctt tatacctttc taaaactgtt cgagcaaatt
     1141 tttcataaaa atgaatcatt ctcctatcaa tccatccatg atattttctt gctaaatata
     1201 atggagtctc atagtgtgaa agagttacaa gtggttctat cccgtgagca tgtagttcat
     1261 caaacaattc atcataatat ttcaacccag cttcgttagg ttcttcctca tctccttttg
     1321 gaaaaattct actccatgca atagaagtac gaaaaacatt aaagcccatt tcagaaaaca
     1381 aggatatatc ttccttatat ttatgataaa aatcaatacc tatcaatttt aagttatctt
     1441 ctgtaggatt ttctgttgct tctcctaatc cacctttggg taacacatcc tgaactgata
     1501 agcccttacc atcttcatta tatgctccct ctacttgatt agctgcaaca gctccacccc
     1561 aaagaaaatc atctggaaaa atggtcataa ctttcctcca ttataatatt accagtaatt
     1621 ccttagaatg ctcgattgtc tgattattag gtaatactaa tacatctaga aaatcattgg
     1681 tattcgttac aattactggt gtaactgttt cgtagccttt agtcttgatt aaattcaagt
     1741 ccatttcaaa aatcaactga tttttgaaaa ctctgtctcc ttcttctaca tgactaataa
     1801 aaccttgacc ttttagctca acagtatcta atccaatatg aattagtaac tcaacaccct
     1861 catcactctt caatccaatt gcgtgcttag tcggaaaaat atttgtaatt ttcccatcaa
     1921 atggtgcata aaccttacct tcacttggaa taatcgctac tccgtctcca attagtttat
     1981 ctgaaaatgt tttatcctgg acatcgctta acggaatgat ttctcctgat ataggagaaa
     2041 atatcatttt tttatttgaa actccagctt taacttctaa attgctagaa ctctcttctt
     2101 catcgattcc aaatatataa gctaatacaa aggtaataac aaccgaaata accgccacaa
     2161 ttaaagcatt tacaatattt gatggtacat cagaataaat aaattgaggc aacgctatca
     2221 aagatgggac agcaaataga tacgctttaa cactagtaag acctgcaaat aatcccgcta
     2281 atccaccacc aatcatagct gcataaagcg gttttttata ttttaaagtc acaccatata
     2341 atgcaggttc ggtaatccct gcaagtaagg ctgagaaacc tgctgcaaaa gcaatttgtt
     2401 ttgtattatt atttttactc tttaatgcaa cagccatcga agcagcccct tgagctaagt
     2461 ttgaccctaa cattgctgga agaattaata cgtctggagt agcaatagat gccgccaaaa
     2521 aaataggtgc aaaagcccaa tgcattccag tcataacaat aaatggcata atagcaccaa
     2581 gaatagctaa tgtaagccat ccagctacat catacatttg cccaactaga tttgataatc
     2641 cttcaccaac aattactcca ataggcccga ctacaactaa ggcaatacag cttgatacta
     2701 ataatactag cgtaggttgc aaaaaactct tagtaacagc tggtgttaat ttagcaatca
     2761 ttttttcaat atatttcatc aaccaaacca taataagaat tggaacgact gacgaaccat
     2821 aactagctgg tatcacaggt acaccaaata aactaagagg attccctgat tgcaccattt
     2881 gaacaaaatt tggatggaga agtacacctg ctacagacat agctaatgta gatgttactt
     2941 ttaatttttg tgatgcagaa taagctaata acagcggtaa gaaataatat ggagcatccc
     3001 caaaaaatgt caaaaaagca atagtctgag aatctgattg caatatacca agcattggta
     3061 aaataattac caagactttc agcatacctc cccctaacat tgctggaatg attggagtca
     3121 tggaaccagc gatatactca atgattcttt ctaaaatatt ccctttgtgc ccttgaacaa
     3181 ctgaatcgga ttcaaaattg ccaagtttaa cgaattcttt ataataatta gctacatcat
     3241 taccaagtat aatttgatat tgtccattct ttttcataat acctattaca cctggtatct
     3301 tcttcacatc atcatcattg actaaatttt catcttttaa ttctaatctt aaacgtgtta
     3361 cacaatgggt aactctattg acattttttt cacctccaat tacatcgagg attttttgta
     3421 ccttatcttt ataactcatg gtattctcct attctattaa tctaaatttt ttgttaagcg
     3481 acgaatatga gccatcaaat aaactaattc actagaagtc agcaaataat tgtactcagt
     3541 ttgtataaac attgccacct gttcaccaca ttcatattct ctaggatatt tatttttcat
     3601 taatgctaac aagtcttcat catcatcgtc acaataagtt gtattttcaa ccaagcgatg
     3661 ggcaaataat tttatatgag ttatgaatct ataataatca atagaatctt ggttaaactc
     3721 agtacaatag aaatcttgaa tgattttctc aattcccata attatttcag tgattttata
     3781 cgactcttga aaattatttt ctaaattagc attaacaaaa tgtagcgcta tgaatgcagc
     3841 ttcgtcaatt ggaagttcaa tacctaactc tttttttatt atttgtaaag cccttttccc
     3901 aagctcaaat tcttctttat aatatttcga gatttcccag cgtaggggat tcgaaataat
     3961 aactccttct ttataacgtt ctatactcga agaaatatga tccgttagat ttatatagat
     4021 aatctcatca aaattattac ctaatgttat tttacctagg ttaattattt tttcggtgat
     4081 gtacaccaac tccaaaggaa cgttaataaa catctctgta aaacgggtca tattatctct
     4141 atttttgaga aaaaaacttt tctcaatatc aattggattt actttatctc cagtttttct
     4201 tccaaaagct attccccttc caaaaagaag aatatcgata tcttttttac tttgcgcaat
     4261 tacggcattg tggtttagta ttcgttttat gatcataaaa tttccctttt aaaataaaag
     4321 gaacctactt aaaaaacatc aagaaacttc ttctgatgtg attaaatagg ttcctgctca
     4381 cttgtattag tgataacatc cttttatttc aatttttaat ggtgacatga agcttaaata
     4441 attaataact ctgtaaccgt ttttatttta tgatatttca atctatttgt caagtactta
     4501 taaaaatttt tttattttgt gtgattcgaa tgtgataatg gcaacagtct cactaaagaa
     4561 atgaaaatca tacatagaaa tttttaaaaa ttttctctat cgtaaacctg ccactagttc
     4621 agaaactata ctagctgatt ccaaacgtaa tatggtcatc tcatctacct tccctaataa
     4681 tggcattgca ccataccaaa caatagtctt attcaccaaa agaataggcg ttactatttt
     4741 tgattgagta aaagacactt taattttctg gctcttcaac tggtctagcc atgctttatt
     4801 tgcaaccgtc tctggtatac atatctcaat ttgactaatc ctaaattctt ttagaaaatt
     4861 catcagtttt gtctggtgca cataaggtaa aataagcaga cattcctgtc tttcccctgc
     4921 taagtcctct ctcaacacct tctcatatct actatcaaca taaacgaatt gtttctcctc
     4981 accctcgatg acacgataat ccatctttcg ataagctact tgtcgtttct gaaacatctt
     5041 ttctaaataa ggaacatgaa tatccacata atcgaaaata cgcaccaaag acttatcctt
     5101 gtagtttcta tgaatccgac ctgcatactg aattaaatta tttttccaag aaaagggtgc
     5161 tgccaagata agcgtgtcca actgaggtaa gtcaaaacct tcgccaatgt attttccagt
     5221 agacaacaaa acaaaccctt tatctaactg ttctaacgtc tccagtaaac tcgttctttc
     5281 tcggactttg gtttttccgc taataatgta acagtcatca acctctttct ctttcaataa
     5341 cttttcaaag acatctatct gttgaattcg attaactaaa accaagatat tccgtccttc
     5401 tgccacttgg gctagaatat ccttgagaat caactgattc ctcgctgagt ctgtagcaat
     5461 ccaatcactg agctgtataa aattacttgc tttggtcttt tcaatctcca aatgaccaaa
     5521 agaagtgaat cttaattgca attgccgttt aaaatccgtt tccctcttat cagcagtatg
     5581 gagtatctca ccaattctct gaaaaacaat aggctcatga ccattcttac gctcaggcgt
     5641 agccgtcaaa ccgtaaagat acttccctct aaactgagca acaacttttt caaacatcaa
     5701 ggcagagaca tgatgacact catccacaat catcatctca tactcatcca aaagactttg
     5761 actattttcc aacttaaata gagattgaat cataacgaca tcaaccagtt tactcagcca
     5821 tttcttagtc ccaccgtact gtccaacata gccgattacc ttttcacgac ctgatgccgt
     5881 ataacggata gcctcctcct cttcgaaagt caaaaagcag tttaagcgat ctagccattg
     5941 gtctaagagt tgcttattat ggactagaat aattgttttt gttttccgtt cagagataag
     6001 agcagcacct aaaacggtct tcccaaaacc agtctccgca tgaagtaaac cattttcttt
     6061 agaagtcata tctgacaggg ctaactcttg ctcaaaagtg agttctccct taaattccac
     6121 gctaatagac ctttgtacct ttctcctatc ttccacagat acctgcttaa atttatcttg
     6181 caatggatat aacaagcctc ttggcagcca taaataataa tcggattctc caaataaata
     6241 cattctctca ggaatttgat aggttggctg tcgcatagcc tgctttaaat aaaattcggg
     6301 attagaaaat gaagccatat ttttcaagaa aaacagtgtc ttgggtgtca cagacgattt
     6361 ttcaagttgg atcatattgg ataagacgat cttcaactcc ttgtccaatt cttgcttgcc
     6421 taactcttct tggattaaca gtgccacttt agcagttgaa accctctgaa tttcttgtag
     6481 atacctccat tggtcttcat aaggctgaaa ctgttcatcc acaaagaccg ttcgcccttg
     6541 atggtaagct tctccttgaa aaggcaaggc aatcaaattt ccaaatcccc cccttaggaa
     6601 ggacatcctg atttggaaac atgcgatcaa aagaatcaaa ggacagttgc atactttcct
     6661 gcattgccag ttctatcagt ttctttccaa acaagcgagc ctctcgactc ggaatcgctt
     6721 cctcaaagaa gaaccaaata tggagtccgt gacccgaacg agaaatctct aaatgggctt
     6781 ccatctggcg ttccctggct attcttcgaa tggttaaacc agcttctttc caatctcctt
     6841 catcaaaatc cagtaccaaa aaatgacagc tatcatctaa gtgcatagga aagataccga
     6901 tagctgtctc cccacgaaaa tgagatttca aaacggagtc cgtcaatgtc tggaaactcc
     6961 gtttttcaag tggcaactgc ttccaaccat aatcatagga aggaaaatac tgaattttcc
     7021 cttgatcatt gataaaactc ttagcataaa catcataacg gccagcaaac acggaggtaa
     7081 acaattgtaa tttttcttgc gtcgtcaagt gactactttg aagttggaac atctcctcga
     7141 accgagagcg ttccatcaca aactgactct tgtctttaag acgtttacac aagaaaaact
     7201 cactatcccc attaaaagaa gaaaagacat caagtacttc taccacaatt ccatccaaag
     7261 acacaaaaat agccataaca atcacctcct tgattcctat aggctgatta taacaagaat
     7321 ggctgaaatt gtacacgaaa ataaaatccg aatagcactc attttgtatg cgactaatag
     7381 tccatctcgc tccggaatgt acgaagtaaa tagagtttaa acgagcagtc tataaaattc
     7441 aaaaaacgca tcatatcagg tgtacatgaa ctacacccca aaagttagac agaaaaaatc
     7501 taacttttgg ggtgttttta ttatgaaatt aa
//
LOCUS       DAVBOD010000076         7514 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 640-05
            SAMEA1012484-rid20186543.denovo.077, whole genome shotgun sequence.
ACCESSION   DAVBOD010000076 DAVBOD010000000
VERSION     DAVBOD010000076.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012484
            Sequence Read Archive: ERR059358
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7514)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7514)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979948.1
            Genome Coverage       :: 595x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:03:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,266
            CDSs (total)                      :: 2,219
            Genes (coding)                    :: 2,091
            CDSs (with protein)               :: 2,091
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 71 of 128
            Pseudo Genes (incomplete)         :: 50 of 128
            Pseudo Genes (internal stop)      :: 33 of 128
            Pseudo Genes (multiple problems)  :: 22 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7514
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012484-rid20186543.denovo.077"
                     /strain="NIG 640-05"
                     /db_xref="taxon:1313"
     gene            complement(109..1959)
                     /locus_tag="VQ862_001943"
     CDS             complement(109..1959)
                     /locus_tag="VQ862_001943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HET3116234.1"
                     /translation="MNKKLTDYVIDLVEILNKQQKQVFWGIFDIFSMVVSIIVSYILF
                     YGLINPAPVDYIIYTSLAFLFYQLMVDFWGLSASISRYSKITDFMKIFFGVTASSVLS
                     YSICYAFLPLFSIRFIILFILLSAFLILLPRITWQLIYSRRKKGSGDGEHRRTFLIGA
                     GDGGALFMDSYQHPTSELELVGILDKDSKKKGQKLGGIPVLGSYDNLPELAKRHQIER
                     VIVAIPSLDPSEYERILQMCNKLGVKCYKMPKVETVVQGLHQAGTGFQKIDITDLLGR
                     QEIRLDESRLGAELTGKTILVTGAGGSIGSEICRQVSRFNPERIVLLGHGENSIYLVY
                     HELIRKFQGIDYVPVIADIQDYDRLLQVFEQYKPAIVYHAAAHKHVPMMERNPKEAFK
                     NNIRGTYNVARAVDEAKVPKMVMISTDKAVNPPNVMGATKRVAELIVTGFNQRSQSTY
                     CAVRFGNVLGSRGSVIPVFERQIAEGGPVTVTDFRMTRYFMTIPEASRLVIHAGAYAK
                     DGEVFILDMGKPVKIYDLAKKMVLLSGHTESEIPIVEVGIRPGEKLYEELLVSTELVD
                     NQVMDKIFVGKVNVMPLESINQKIGEFRTLSGDELKQAIIAFANQTTHIE"
     gene            complement(2027..3166)
                     /locus_tag="VQ862_001944"
     CDS             complement(2027..3166)
                     /locus_tag="VQ862_001944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000096190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HET3116235.1"
                     /translation="MSSKVSGFQDKNGKVLKIMIEWWKGKFRRVVVTQNVESLLVSIV
                     ISAYNEEKYLPGLIEDLKNQTYPKENIEILFINAMSTDGTTAIIQQFIKEDAEFNSIR
                     LYNNPKKNQASGFNLGVKHSVGGLILKIDAHSKVTESFVMNNVAVIQQGEFVCGGPRP
                     TIVKGKGKWAETLHLVEENMFGSSIANYRNSSEDRYVSSIFHGMYKREVFQKVGLVNE
                     QLGRTEDNDIHYRIREHGYKIRYSPSILSYQYIRPTFKKMLHQKYSNGLWIGLTSHVQ
                     FKCLSLFHYVPCLFVLSLVFSLALLPITFVFITLLLGAYFLLLSLLSLLTLLTLLKHK
                     NGFLIVMPFLLFSIHFAYGLGTIVGLIRGFKWKKEYKGTVIYLEK"
     gene            3224..4390
                     /locus_tag="VQ862_001945"
     CDS             3224..4390
                     /locus_tag="VQ862_001945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CynX/NimT family MFS transporter"
                     /protein_id="HET3116236.1"
                     /translation="MKKQSLFFVPGIILIGVSLRTPFTVLPIILGNISQGLEVEVSSL
                     GVLTSLPLLMFTLFSPFSTRLAQKIGLEHLFTYSLFFLTIGSLIRLINLPLLYLGTLM
                     VGASVAVINVLLPSLIQANQPKKIGFLTTLYVTSMGIATALASYLAVPITQASSWKGL
                     ILLLTLLCLATFLVWLPNHRYNHRLAPQTKQKSQIKVMRNKQVWAIIIFSGFQSLIFY
                     TAMTWLPTMSIHAGLSSHEAGLLTSILSLISIPFSMTIPSLTTSLSTRNRQLMLTLVS
                     LAGVVGISMLFFPINNFIYWLAIHLLIGTATSALFPYLMVNFSLKTSAPEKTAQLSGL
                     SQTGGYILAAFGPTLFGYSFDLFHSWVPAVAALLLIDILMTVALFTVDRADKIL"
     gene            4529..4855
                     /locus_tag="VQ862_001946"
     CDS             4529..4855
                     /locus_tag="VQ862_001946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000273865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HET3116237.1"
                     /translation="MYFPTSSALIEFLILAVLEQGDSYGYEISQTIKLIANIKESTLY
                     PILKKLEGNSFLTTYSREFQGRMRKYYSLTNGGIEQLLTLKDEWALYTDTINGIIEGS
                     IRHDKN"
     gene            4842..5435
                     /locus_tag="VQ862_001947"
     CDS             4842..5435
                     /locus_tag="VQ862_001947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000198695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1700 domain-containing protein"
                     /protein_id="HET3116238.1"
                     /translation="MTRTEYLTQLELYLKKLPEADRIEAMDYFRELFDDAGVEGEEEL
                     IASLGTPKEAAHEVLSNLLDKKINEAPAQKNNRQILHIALLALLAAPIGIPLGIAILV
                     TLFAILVAALTVILAFFAVSILGIIGGFLFLVESFTVLAQAKSAFILIFGSGLLAIGA
                     SSLVLLGISYVARFFGLLIVRLVQFVLKKRKRGNQHA"
     gene            5428..6339
                     /locus_tag="VQ862_001948"
     CDS             5428..6339
                     /locus_tag="VQ862_001948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001233690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4097 domain-containing protein"
                     /protein_id="HET3116239.1"
                     /translation="MRKWTKGFLIFGVVTTVIGFILLFVGIQSDGIKSLLSMSKEPIY
                     DSRTEKLTFGKEVENLEITLHQHALTITDSFDDQIHISYHPSLSAHHDLITNQNDRTL
                     SLTDKKLSETPFLSSGIGGILHIASSYSSRFEEVILQLPKGRTLKGINISANRGQTTI
                     INASLENATLNTNSYILRIEGSRIKNSKLTTPNIVNIFDTVLTDSQLESTENHFHAEN
                     IQVHGKVELTAKDYLRIILNQKESQRINWDISSNYGSIFQFTREKPESRGTELSNPYK
                     TEKTDVKDQLIARSDDNIDLISTPSRR"
     gene            6402..7466
                     /locus_tag="VQ862_001949"
     CDS             6402..7466
                     /locus_tag="VQ862_001949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000808437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3116240.1"
                     /translation="MKQEWFESNDFVKTTSKNKPEEQAQEVADKAEETIADLDTPIEK
                     NTQLEEEVPQAEVELESQQEEKIEAPEDSEARTEIEEKKASNSTEEEPDLSKETEKVT
                     IAEESQEALPQQKATTKEPLLISKSLESPYIPDQAPKSRDKWKEQVLDFWSWLVEAIK
                     SPTSKLETSITHSYTAFLLLILFSASSFFFSIYHIKHAYYGHIASINSRFPEQLAPLT
                     LFSIISILVATTLFFFSFLLGSFVVRRFIHQEKDWTLDKVLQQYSQLLAIPIFLTAIA
                     SFFAFFDSLRFTALLCVISIGIILLASLHIITRPSQASETDSFYQLFLSVLVNGVIIL
                     LFFVAEVALIGDYLRILAFL"
BASE COUNT         2281 a         1719 c         1311 g         2203 t
ORIGIN      
        1 aaggtgaaac tgacgtggtt tgaagagatt ttcgaagagt ataagtctct acataataaa
       61 acgcatatta ccaaggttat ttgacttgat aatatgcgtt tttctttttt attcaatgtg
      121 ggttgtttga ttagcaaagg cgataatagc ttgcttcaac tcatctccac tgagagtgcg
      181 gaactctcca atcttttgat tgatggattc taaaggcatg acattaacct taccaacgaa
      241 aatcttatcc ataacttgat tatcaacgag ttcggttgat accaagagtt cttcgtagag
      301 tttttcacct gggcggattc caacttcaac gattggaatt tcactttcag tgtggccact
      361 tagaagcacc atcttcttgg ccaagtcata aatcttgact ggtttgccca tatcaaggat
      421 aaagacttcc ccatctttgg cataagcacc agcatggata accagacggc tagcttctgg
      481 aatggtcata aagtaacggg tcatgcggaa gtctgtcacc gttacaggcc caccttcagc
      541 aatctgacgt tcaaagactg gaatgacact accacggcta ccaagaacat tcccaaaacg
      601 aactgcacag taggttgatt ggctacgttg gttaaagcca gtgacaatca actccgccac
      661 gcgcttggtt gctcccataa catttggtgg attgactgcc ttatctgtcg aaatcataac
      721 catcttaggc accttggctt catcaacggc tctagcaaca ttgtaagttc cacggatatt
      781 gtttttgaag gcttcttttg gattgcgctc catcatagga acatgcttgt gggctgccgc
      841 atgataaaca atagcaggtt tgtactgctc aaagacttgc aacaaacgat catagtcttg
      901 aatgtccgca atcacaggta cataatcaat cccttggaac ttacgaatca attcatgata
      961 aacaaggtag attgagtttt ccccatgacc gagcaagaca atgcgttcag gattgaagcg
     1021 actaacttga cgacagattt cagaaccgat tgaacctcca gctcctgtga ctaagatggt
     1081 cttacctgtc agttctgcac ccagacgcga ttcgtcaaga cggatttcct gacgacccaa
     1141 aaggtccgta atatcaattt tttggaagcc agtacctgct tggtgaaggc cctgaacaac
     1201 agtttcaacc ttaggcatct tgtaacattt gacacccagc ttattacaca tctgcaagat
     1261 acgctcatat tctgacggat ccagcgacgg aatcgcaacg atgacacgct cgatttgatg
     1321 gcgtttggct aattcaggca gattgtcata agagcccaaa acaggaatac caccaagttt
     1381 ttgacccttt ttcttagaat ccttatccaa aataccgacc agttctaatt cactggttgg
     1441 atgttggtaa ctatccataa agagagcccc accatcaccg gcaccaatca agaaggtccg
     1501 acggtgttct ccatcaccac tacctttttt gcgtctggag tagattaact gccaagtaat
     1561 ccgtggcaat aaaatcaaga aggcactcaa caagataaag agaatgataa aacggatgga
     1621 gaagagtggc aagaaggcat aacagatact atatgacaag acactgctag cagtcacacc
     1681 aaaaaagatt ttcatgaaat ccgtaatctt gctgtaacga ctaatactcg cgctcaagcc
     1741 ccaaaaatca accatcaatt gatagaacag gaaggccaaa ctcgtataga taatgtagtc
     1801 aacaggtgct ggattaatca gcccataaaa taaaatataa gatacaatga tggaaaccac
     1861 catactgaaa atatcaaata ttccccagaa aacctgcttt tgttgtttat ttaaaatttc
     1921 caccagatca atcacataat ctgtgagttt tttattcata gaaatttact cctccttaaa
     1981 atagttctac tatattgtta ttatagcaca ttttaattta tttggcttat ttttccaaat
     2041 aaattactgt tcccttgtac tccttcttcc atttaaatcc tctaattaaa cctacaatcg
     2101 tcccaaggcc ataagcaaag tgaatggaaa ataaaagaaa gggcatcaca attagaaatc
     2161 catttttatg ttttaataaa gtcagcaaag tgagtaatga cagtaatgat aaaagtagaa
     2221 aataggcacc taatagtaaa gttatgaata cgaatgtgat cggtaacaat gctagactaa
     2281 acacaagact caaaacaaat aaacaaggaa cataatgaaa taatgataaa cacttaaact
     2341 gaacatgact tgtcaagcca atccacaaac catttgaata cttttgatgc agcattttct
     2401 tgaatgttgg tcgaatatac tgataagata gaatacttgg gctatagcgg attttataac
     2461 catgttctcg aattctataa tgaatatcat tatcttcagt tcggccaagt tgctcattta
     2521 ctaaaccaac cttctggaaa acctctcgtt tatacatccc atgaaaaata gaagaaacat
     2581 atctatcctc ggaactattt cgataattgg caatgctact gccaaacata ttttcctcaa
     2641 caagatgcaa ggtctctgcc cattttcctt ttcctttgac aatcgtcggt ctaggccctc
     2701 cacagacaaa ttcaccttgt tgaataacag ccacattgtt cattacaaaa ctctcagtaa
     2761 cttttgaatg agcatcaatt tttaaaataa ggccccctac agaatgctta actcccaggt
     2821 taaaaccact agcttgattt ttcttaggat tgttatacaa tctaattgag ttaaactctg
     2881 catcttcttt tataaattgc tgaatgatag ctgtggtccc atctgtggac atagcattta
     2941 taaatagaat ttcaatattc tctttaggat aggtttgatt ttttaagtct tcaattagac
     3001 caggcagata tttttcttca ttgtatgcac tgattacaat ggatacgaga agactttcaa
     3061 cattttgagt cactactact ctcctgaatt ttcccttcca ccattctatc ataattttca
     3121 agacttttcc atttttatct tgaaagccag aaaccttact tgacattata gtgaaaaagc
     3181 cttaaaataa gctgttatta aaatcagcta gaagagatat tatatgaaaa agcaatcact
     3241 cttttttgtt ccaggtatta tcctgattgg tgtttccttg cgaactcctt ttactgtttt
     3301 acccattatt ttgggaaata tttcgcaagg tctggaggta gaagttagtt cgcttggtgt
     3361 cttgaccagc ctgcctctcc ttatgtttac cctcttttca ccattttcta cccgactggc
     3421 tcagaaaatc ggcttggagc atctcttcac ctacagcctc ttcttcttga ccatcggctc
     3481 acttattcga ctaatcaatc tgcccctgct ctatctagga accttgatgg ttggggcaag
     3541 tgtcgcagtc atcaatgtcc tgcttcctag tcttatccaa gccaatcaac caaagaaaat
     3601 tggttttctg accaccttat atgtaacgtc tatggggatt gcaacggctc tggcttccta
     3661 tctagctgtg cccattacac aagccagttc ttggaaagga cttatcctcc tcctcacgtt
     3721 actctgtcta gcaacttttt tggtctggct cccaaatcac cgctataatc atagactagc
     3781 tccacaaacc aaacaaaaaa gtcaaataaa ggtcatgcgt aataaacagg tttgggcaat
     3841 tattatcttt tcaggttttc aatccttgat cttttacacc gccatgacct ggttacctac
     3901 catgtctatc catgcaggtc tatccagtca cgaagctggc ttgctgactt ctatcttatc
     3961 tctgattagc attccttttt caatgaccat cccaagcctg acaaccagtt tatctactcg
     4021 caaccgtcag ctcatgctca ctctggtttc actagctggt gtggtcggca tttccatgct
     4081 ctttttccca atcaataatt tcatttactg gcttgccatc catctcctca tcggaaccgc
     4141 aaccagcgcc ctcttccctt atctcatggt caacttttca ctcaagacaa gcgcccctga
     4201 aaagacagcc caattgtccg gcctatctca aacaggaggc tatatcctag cagcctttgg
     4261 gccaaccctc tttggttaca gttttgacct attccactct tgggtaccag ctgtagctgc
     4321 cctcttgctc atcgatatcc tgatgactgt ggccctcttt acagtggaca gagcggataa
     4381 gatcctttaa acttctagtt ttagctagaa gttttttata tataaaaatt ttacacattt
     4441 ctcttgacag ggctttcttt tagatgtaca atgtatgtgt agaaaaatta tatataaaaa
     4501 tcttacacat tagaaaagga ggtttcccat gtactttcca acatcctctg ccttgattga
     4561 atttctcatc ttggccgtac tggagcaggg tgattcttat ggttatgaga ttagccaaac
     4621 cattaagctg atcgctaata tcaaagaatc cacactctat cccattctca aaaaattgga
     4681 aggcaatagc tttctgacaa cctattctag agagttccaa ggtcgcatgc gcaaatacta
     4741 ctccttgaca aacggtggta tagagcagct cttgacccta aaagatgaat gggcactcta
     4801 tacagacacc atcaatggca tcatagaagg gagtatccgc catgacaaga actgaatacc
     4861 tgactcagct agaactctat ctcaagaaac tacctgaagc tgaccgtatc gaagccatgg
     4921 actatttcag agagctcttt gacgatgctg gagtcgaagg agaagaagaa ctcatcgcta
     4981 gtttgggaac tcccaaagaa gcggcccacg aagttctatc caatcttctc gataaaaaaa
     5041 tcaatgaagc acccgctcaa aaaaataacc gacaaatttt acatatcgcc ttgttagccc
     5101 tccttgcagc acctatcggc attcctctgg gaatcgccat cctcgtgacc ctgttcgcaa
     5161 tccttgtagc cgctttgact gtcattctgg ctttctttgc agtttccata ctgggtatca
     5221 tcggcggatt cctattttta gttgaaagtt tcactgtcct cgcccaagcc aaatcagcct
     5281 ttatcttgat ttttggttct ggtttactgg ctatcggtgc ttcttcgcta gttttactag
     5341 gcatttccta tgtagctcgc ttcttcggtc tactcattgt tcgcctggta caatttgttc
     5401 ttaaaaaaag aaagagaggt aaccagcatg cgtaaatgga caaaaggatt tctcatcttt
     5461 ggtgtggtga ctaccgttat cggctttatc cttctttttg taggtatcca atctgacggg
     5521 attaaaagcc tactttccat gtccaaagaa cctatctatg atagccgtac ggaaaagcta
     5581 acctttggca aggaagtcga aaacctagaa attactctcc accaacacgc gctcaccatc
     5641 acagactctt tcgatgatca aatccacatt tcttaccatc catctctttc tgctcaccat
     5701 gatcttatca ccaatcagaa cgatagaact ctgagtctca ctgataagaa actgtctgaa
     5761 actccgtttc tctcttctgg aattggtggg attcttcata tcgcaagtag ctactctagt
     5821 cgttttgaag aagttattct ccagctacca aaagggagaa ctctaaaagg gatcaacatc
     5881 tcagccaatc gcggacaaac caccatcata aatgctagcc ttgaaaatgc gaccctcaat
     5941 acaaacagct atatcctccg aattgaagga agtcgtatca aaaacagtaa actcacaacg
     6001 cccaatatcg ttaatatctt tgatacagtt cttacagata gtcagctaga gtcaacagag
     6061 aatcacttcc acgctgaaaa tatccaagtc catggcaagg ttgaactgac tgccaaagat
     6121 tatctcagaa tcatcctaaa ccagaaagaa agccaacgaa ttaactggga catctcaagc
     6181 aactatggtt ctatcttcca attcacaaga gaaaagcctg aatcaagagg tacggaatta
     6241 agcaaccctt acaaaactga aaaaaccgat gtcaaggatc aactcattgc gagatctgat
     6301 gataatattg atctaatatc cacaccaagc agacgttgac aaaaacgctt acatctgcta
     6361 ctatggaagc atatttatct aactaaaaag gaggttctac catgaaacaa gaatggtttg
     6421 aaagtaatga ttttgtaaaa acaacaagca agaacaagcc tgaagagcaa gctcaagagg
     6481 ttgcagacaa ggctgaagaa acgatagccg atctcgatac accaattgaa aaaaatactc
     6541 agttagagga ggaagtccct caagctgaag tcgaattgga aagccagcaa gaagagaaaa
     6601 ttgaagctcc tgaagacagt gaagcgagaa cagaaataga agaaaagaag gcatctaatt
     6661 ctactgaaga agagccagac ctttctaaag aaacagaaaa agtcactata gctgaagaga
     6721 gccaagaagc tcttcctcag caaaaagcaa ccacgaaaga gccacttctt atcagtaaat
     6781 ctttagaaag tccttatatc cccgaccaag ctccaaaatc tagggataaa tggaaagagc
     6841 aagtgcttga tttttggtct tggctagtgg aagcgatcaa atctcctaca agtaagttgg
     6901 aaacaagtat cacacacagt tacacagcct ttctcttgct cattctgttt tctgcatctt
     6961 cctttttctt tagtatctat cacatcaaac atgcttacta tggacatata gcaagcatta
     7021 acagtcgctt ccctgagcag ctagctcctt taactctttt ttctatcatc tctatcctag
     7081 tagcgacaac actcttcttc ttttcattcc tcttgggtag tttcgttgtg agacgattta
     7141 tccaccagga aaaggactgg acgctagaca aggttctcca acaatatagt caactcttag
     7201 caattccaat cttcctcact gctattgcta gtttctttgc tttctttgat agcctacgat
     7261 ttacagccct cttgtgtgtg attagcattg gaatcattct gcttgccagt ctccatatca
     7321 ttacaagacc aagtcaagca agtgaaaccg actccttcta tcaattattc ttgtctgtcc
     7381 ttgtgaacgg agttattatc ctcctcttct ttgtagctga agtggcactg attggagatt
     7441 atcttcgtat cttggccttt ctttaaactt catactcttc gaaaatcaaa ttcaaaccac
     7501 gtcagcttcg cctt
//
LOCUS       DAVBOD010000077         7483 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 640-05
            SAMEA1012484-rid20186543.denovo.078, whole genome shotgun sequence.
ACCESSION   DAVBOD010000077 DAVBOD010000000
VERSION     DAVBOD010000077.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012484
            Sequence Read Archive: ERR059358
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7483)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7483)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979948.1
            Genome Coverage       :: 595x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:03:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,266
            CDSs (total)                      :: 2,219
            Genes (coding)                    :: 2,091
            CDSs (with protein)               :: 2,091
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 71 of 128
            Pseudo Genes (incomplete)         :: 50 of 128
            Pseudo Genes (internal stop)      :: 33 of 128
            Pseudo Genes (multiple problems)  :: 22 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7483
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012484-rid20186543.denovo.078"
                     /strain="NIG 640-05"
                     /db_xref="taxon:1313"
     gene            156..311
                     /locus_tag="VQ862_001950"
                     /pseudo
     CDS             156..311
                     /locus_tag="VQ862_001950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000710121.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
     gene            511..3786
                     /gene="rexB"
                     /locus_tag="VQ862_001951"
     CDS             511..3786
                     /gene="rexB"
                     /locus_tag="VQ862_001951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent nuclease subunit B"
                     /protein_id="HET3116241.1"
                     /translation="MKLLYTDIRTSLTEILTREAEELVAAGKRVFYIAPNSLSFEKER
                     AVLECLSQQASFSITVTRFAQMARYLVLNDLPAKTTLDDIGLGLAFYKCLAELDPKDL
                     RVYGAIKQDPQLIQQLIELYHEMTKSQMSFLDLENLTDEDKRADLLLIFEKVTAYLNQ
                     GQLAQGSQLSHLIEAIENDKVSSDFNQITLVIDGFTRFSAEEERVVDLLHGKGVEIVI
                     GAYASKKAYTSPFSEGNLYQASVKFLHHLASKYQTPAQDCSQTHEKMDSFDKASRLLE
                     SSYDFSELALDVDEKDRENLQIWSCLTQKEELELVARSIRQKLHENSDLSYKHFRILL
                     GDVASYQLSLKTIFDQYQIPFYLGRSEAMAHHPLTQFVESILALKRYRFRQEDLINLL
                     RTDLYTDLSQSDIDAFEQYIRYLGINGLPAFQQIFTKSHHGKFNLERLNVLRLRILAP
                     LETLFASRKQKAENLLQKWSVFLKEGAVTKQLQDLTTTLEAVEQERQAEVWKAFCHVL
                     EQFATVFAGSQVSLEDFLALLHSGMSLSQYRTIPATVDTVLVQSYDLIAPLTADFVYA
                     IGLTQDNLPKISQNTSLLTDEERQNLNQATEEGVQLLIASSENLKKNRYTMLSLVNSA
                     RKQLFLSAPSLFNESESKESAYLQELIHFGFRRREKRMNHKGLSKEDMGSYHSLLSSL
                     VAYHQQGEMSDTEQDLTFVKVLSRVIGKKLDLQGLENPAIPTSPSSKTLAKDTLQALY
                     PAKQEFYLSTSGLTEFYRNEYSYFLRYVLGLQEELRLRPDARSHGNFLHRIFERALQL
                     PNEDSFDQRLEQAIQETSQEREFEAIYQESLEAQFTKEVLLDVARTTGHILRHNPAIE
                     TIKEEANFGGKDQAFIQLDNGRSVFVRGKVDRIDRLKANGAIGVVDYKSSLTQFQFPH
                     FFNGLNSQLPTYLAALKREGKQNFFGAMYLEMAEPVQSLMAVKSLAGAVVEASKSMKY
                     QGLFLEKESSYLGEFYNKNKANQLTDEEFQLLLDYNAYLYKKAAEKILAGRFAINPYT
                     ENGRSIAPYVQQHQAITGFEANYHLGQARFLEKLDLADGKRLVGEKLKQAWFEKIREE
                     LNR"
     gene            3783..7433
                     /gene="addA"
                     /locus_tag="VQ862_001952"
     CDS             3783..7433
                     /gene="addA"
                     /locus_tag="VQ862_001952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000767270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase-exonuclease AddAB subunit AddA"
                     /protein_id="HET3116242.1"
                     /translation="MKLIPFLSEEEIQKLQEAEANSSKEQKKTAEQIEAIYTSGQNIL
                     VSASAGSGKTFVMAERILDQLARGVEISQLFISTFTVKAATELKERLEKKISKKIQET
                     DDVDLKQHLGRQLADLPNAAIGTMDSFTQKFLGKHGYLLDIAPNFRILQNQSEQLLLE
                     NEVFHEVFEAHYQGKQKESFSHLLKNFAGRGKDERGLRQQVYKIYDFLQSTSNPQKWL
                     SESFLKGFEKADFTSEKEKLTEQIKQALWDLERFFRYHLDNDAKEFAKAAYLENVQLI
                     LDEIGSLNQEFDSQAYQAVLARVVAISKEKNGRALTNASRKADLKPLADAYNEERKTQ
                     FTKLGQLSDQIAILDYQERYHGDTWKLAKTFQSFMSDFVEAYRQRKRQENAFEFADIS
                     HYTIEILENFPQVRESYQERFHEVMVDEYQDTNHIQERMLELLSNGHNRFMVGDIKQS
                     IYRFRQADPQIFNEKFQRYAQNPQEGKLILLKENFRSSSEVLSATNDVFERLMDQEVG
                     EINYDNKHQLVFANTKLTPNPDNKAEFLLYDKDDTGEEEESQTETKLTGEMRLVIKEI
                     LKLHQEKGVAFKEIALLTSSRSRNDQILLALSEYGIPVKTDGEQNNYLQSLEVQVMLD
                     TLRVIHNPLQDYALVALMKSPMFGFDEDELARLSLQKAEDKVHENLYEKLVNAQKMAS
                     SQKGLIHTALAEKLKQFMDILASWRLYAKTHSLYDLIWKIYNDRFYYDYVGALPNGPA
                     RQANLYALALRADQFEKSNFKGLSRFIRMIDQVLEAQHDLSSVAVAPPKDAVELMTIH
                     KSKGLEFPYVFILNMDQDFNKQDSMSEVILSRQNGLGVKYIAKMETGAVEDHYPKTIK
                     LSIPSLTYRQNEEELQLASYSEQMRLLYVAMTRAEKKLYLVGKGSREKLEVKQYPAAK
                     NGKLNSNTRLQARNFQDWLWAISKVFTKDKLNFSYRFIGEDQLTREAIGELETKSPLQ
                     DSSQADNRQSDTIKEALEMLKEVEVYNTLHRAAIELPSVQTPSQIKKFYEPVMDMEGV
                     EIAGQGQSVGKKISFDLPDFSTKEKVTGAEIGSATHELMQRIDLSQQLTLASLTETLK
                     QVQTSQAVRDKINLDKILAFFDTVLGQEILANTDHLYREQPFSMLKRDQKSQEDFVVR
                     GILDGYLLYENKIVLFDYKTDRYDEPSQLVDRYRGQLALYEEALSRAYSIENIEKYLI
                     LLGKDEVQVVKV"
BASE COUNT         2275 a         1573 c         1593 g         2042 t
ORIGIN      
        1 cattgtgtac tatttttggt tcattttact atagtagatt gaaataagat acgaacagct
       61 tgattaggga aatcaaatta atttctagaa atattttagc atccacggtg tactattata
      121 gtttcaattt actatagttc aatcattcta tcaagaatat tgaatatata aaggcacgta
      181 atattaaaac ttcttctgat atcgaattag agtccgatgt tgatggcgat aaatcagaca
      241 atctaccagt cgacattaag atactgggac aacacattga agtgtattcc gtacctaaga
      301 aacaatcata aaactcaaag ccttgttacc gaggcttttt tattatgtga ttttcagtag
      361 ccagacttat tctatctaat acaagtaaag ctaagtattt aagatttagc agatgatgaa
      421 gaaaagaaag gatggcctaa atattttaac agatttacga ggctaatcat ggtataatat
      481 agggtgatga aaaattccaa cgaggctgag atgaaattac tttatactga tattcggact
      541 tctttgacag aaattctaac aagagaggca gaagagctag ttgcagctgg caagcgggtc
      601 ttctacattg cccccaactc tctttctttt gaaaaggaac gcgccgtgct ggaatgcttg
      661 tcccagcagg cttctttttc gattaccgtc acgcgctttg ctcaaatggc tcgttatctg
      721 gtcttgaatg atttaccagc taaaactact cttgatgata tcggtcttgg gttggccttt
      781 tacaaatgcc ttgccgaact cgatcccaag gacttgcgtg tttatggcgc tattaagcag
      841 gatcctcaat tgatccagca gttaattgag ctttaccatg agatgaccaa atcccagatg
      901 agttttttgg acttggagaa tttaacagat gaggataaga gggcggattt actcttgatt
      961 tttgagaaag taacagccta tcttaatcaa ggtcagttag cccagggaag tcagttgtcc
     1021 catttgattg aggctattga gaatgacaag gtaagtagtg attttaatca aatcaccttg
     1081 gtcattgacg gctttactcg tttttctgct gaggaagagc gggttgtgga cttacttcac
     1141 ggcaaaggtg ttgagattgt tatcggggct tatgctagta agaaagccta taccagtcct
     1201 tttagcgagg gcaatctcta ccaagccagc gtaaaatttc tccatcatct ggcttctaaa
     1261 taccaaacgc ctgctcagga ctgttctcaa actcatgaga agatggatag ttttgacaag
     1321 gcctctcgtt tgttggagtc ttcttatgac ttttcagaac tcgctttgga tgtcgatgag
     1381 aaagaccgtg aaaatttaca aatctggtct tgtttgacgc aaaaggagga gttggagcta
     1441 gtagcccgta gtattcgtca gaaattacat gagaactcag acctgagcta caagcatttt
     1501 cgtattctct tgggggatgt agcttcttac cagttatctc tcaaaaccat ttttgaccag
     1561 tatcagattc ctttttatct tggtagaagc gaagccatgg ctcatcatcc cttgactcag
     1621 tttgtcgagt ctattttagc tttaaaacgt taccgttttc gtcaggagga tttgattaat
     1681 cttcttagaa ctgatttgta tactgacctc agtcagtctg atattgatgc ttttgagcaa
     1741 tatatccgct atcttggtat caatggcttg ccagcctttc agcaaatctt caccaaatcc
     1801 caccatggaa aatttaatct tgagcgtttg aatgtcctcc gcctgagaat tttagcacct
     1861 cttgaaaccc tctttgccag ccgaaaacaa aaggctgaaa acctcctaca aaaatggagt
     1921 gtctttctaa aagaaggagc tgtgaccaag cagttacaag atttgacaac cactttggaa
     1981 gctgtagaac aggaaagaca agccgaagtt tggaaggctt tctgccatgt tttagaacaa
     2041 tttgcgactg tttttgctgg ttcacaggtt agtctggaag acttcctagc cttgctccat
     2101 tctggaatga gtttgtccca ataccgtacc attccagcaa cagtggacac tgttctggtg
     2161 cagagttacg atttgattgc accattgact gctgactttg tctatgctat tggactaact
     2221 caggacaatt taccaaaaat ttctcaaaac accagtcttc tgacagatga agaaaggcaa
     2281 aacctaaacc aagcgaccga agaaggcgtt caattactga ttgccagcag tgaaaatctc
     2341 aagaaaaatc gctacactat gctttccttg gtcaattctg ctcgtaagca gttgttcttg
     2401 tcggctccaa gcctttttaa cgaaagtgaa agtaaggaat ctgcctatct tcaagagttg
     2461 atccattttg gatttaggcg gagagagaag aggatgaatc acaaaggact gtctaaggag
     2521 gatatggggt cctatcacag tcttttgtct agtctggttg cctatcacca gcagggtgag
     2581 atgagcgata ctgagcaaga tttgactttt gtcaaggttc tgtcgcgtgt cataggtaaa
     2641 aaactagatc tgcaaggtct ggaaaatcca gctatcccaa ccagtccaag cagcaagacc
     2701 ttagccaagg acaccttgca agctctctat cctgccaaac aggagtttta cctgtctacg
     2761 tcgggtttga cagagtttta tcgcaatgaa tacagttatt tcctacgcta cgttttaggc
     2821 ttgcaggagg aattacgttt gcgtcctgat gcccgtagtc acgggaattt cttgcatcgt
     2881 atctttgaac gcgccttaca gttgcctaat gaagattcct ttgaccaacg tctagaacaa
     2941 gctattcaag aaaccagtca agaacgcgaa tttgaagcta tttatcaaga aagtttggaa
     3001 gcccagttta ccaaggaagt tttgcttgat gttgcacgga cgactggaca tattctccga
     3061 cacaatccag ccatcgaaac catcaaagaa gaagcaaatt ttggtggaaa agaccaagcc
     3121 tttattcaat tagacaatgg acgcagtgtc tttgtacgag gcaaggtgga ccggattgac
     3181 cgtttgaaag ctaatggtgc gataggagta gtagactaca aatccagtct gactcagttc
     3241 cagtttcctc atttctttaa tgggctcaat tctcagttac caacctatct tgctgcccta
     3301 aaaagagaag ggaagcagaa ctttttcggc gccatgtact tggaaatggc tgaacctgtc
     3361 caatctctga tggcggtaaa aagtctggca ggagcagtgg tagaagccag caaatctatg
     3421 aaataccaag ggctcttctt ggaaaaagaa agcagttatt taggcgaatt ttataacaaa
     3481 aacaaggcta atcaactgac agatgaggaa tttcagctcc tactggacta caatgcctat
     3541 ctttacaaga aagctgctga gaagatttta gcaggccggt tcgccatcaa tccttatact
     3601 gaaaatggca gaagcattgc cccatacgtc cagcaacatc aggctattac aggctttgaa
     3661 gccaattacc atctgggcca agcccgtttc ctagaaaaat tggacctagc tgatggcaag
     3721 cgtctggtcg gagaaaaact caagcaagct tggtttgaaa aaataagaga ggagttaaat
     3781 cgatgaagct tattcccttt ttaagtgagg aggagattca aaaactgcaa gaagcagaag
     3841 caaattcgag caaggaacag aagaaaactg ccgaacaaat cgaagctatc tacacttctg
     3901 gtcagaatat cctggtctca gcatcggctg gttctggaaa gacctttgtc atggcagagc
     3961 gcattctgga ccaattggcg cgtggtgtcg aaatttctca actctttatc tcaaccttta
     4021 ccgtcaaggc tgcaactgaa cttaaagaac gtttagagaa aaaaatcagc aagaaaatcc
     4081 aagaaacaga tgatgtcgat ctcaaacaac acttgggtcg ccagttggca gacctaccca
     4141 acgctgccat cggaaccatg gactctttta cacaaaaatt ccttggcaaa catggttatc
     4201 tgcttgatat tgcacctaat ttccgtattt tacaaaacca aagcgagcaa cttcttctcg
     4261 aaaacgaagt ctttcatgag gtctttgaag cgcattacca aggtaaacag aaagagagct
     4321 ttagtcattt gctgaaaaac tttgctgggc gtggcaagga cgaacggggt ctgcggcagc
     4381 aagtctataa aatctatgac ttcctccaat ccaccagtaa tcctcaaaag tggctgagtg
     4441 aatctttcct caaaggcttt gagaaagctg attttaccag tgaaaaagaa aaactgactg
     4501 agcaaatcaa acaagccctc tgggatttgg aaagattttt ccgttaccat ctggataacg
     4561 atgccaagga gtttgcaaag gctgcctatt tagaaaatgt tcagttaatt ctggatgaaa
     4621 ttggctccct aaatcaggag ttcgatagtc aggcttatca ggcagtactt gcgcgtgttg
     4681 tcgccatctc taaggagaaa aacggtcgtg ctctgactaa tgccagccgt aaggctgatt
     4741 tgaagcccct ggctgatgcc tacaacgaag agagaaagac ccagtttact aaactaggac
     4801 aattatcaga ccagatagcg attctcgact atcaagaacg ttatcatgga gacacttgga
     4861 aactagctaa aaccttccaa tctttcatga gcgattttgt agaggcttat cgtcagagaa
     4921 aacgacagga aaatgccttt gaattcgctg atatcagcca ttacaccatt gagattttag
     4981 aaaatttccc acaagttcgt gagtcttatc aggagcgctt ccatgaagtc atggtcgatg
     5041 agtatcagga taccaaccat attcaagaac ggatgctgga attgttgtct aatggccaca
     5101 atcgctttat ggtgggagat atcaagcaat ccatctatcg tttccgtcag gcagacccgc
     5161 agattttcaa tgagaaattc caacgctatg cgcaaaatcc ccaagaaggc aagctcattc
     5221 tcctcaagga aaatttccgt agtagttcag aagtgctgtc agcaaccaat gatgtctttg
     5281 aacgtctcat ggaccaagag gtcggcgaaa tcaactatga taacaagcac cagcttgttt
     5341 ttgccaatac caaactgact cccaatccag acaacaaggc agaatttctc ctctacgaca
     5401 aggacgatac aggtgaggaa gaagagagtc aaacagaaac gaaactaaca ggcgaaatgc
     5461 gcttagttat caaggagatt ctgaaacttc atcaagaaaa aggtgttgcc tttaaggaaa
     5521 ttgcccttct gacctccagc cgcagtcgta atgaccagat tctcctcgcc ctgtctgagt
     5581 acgggattcc tgtcaaaact gacggagagc aaaacaatta tctccaatcc ctagaagtgc
     5641 aagtcatgct agacactctt cgtgtcattc acaatcccct gcaagactat gccttggttg
     5701 cccttatgaa gtctccaatg tttggttttg atgaggatga gctagcacgt ttgtcccttc
     5761 agaaagcaga ggataaagtc cacgaaaatc tctatgagaa actggtcaat gcacaaaaaa
     5821 tggcaagtag tcaaaaaggc ttgattcaca cagctctagc tgaaaaacta aagcaattca
     5881 tggatatcct agcttcttgg cgcttgtatg ccaaaaccca ctctctctat gacttgattt
     5941 ggaagattta caacgaccgt ttttattatg actatgttgg ggctttgccg aatggtcctg
     6001 ctaggcaggc caatctctat gccctagcac tgcgtgctga tcaatttgaa aagagcaatt
     6061 tcaaaggttt gtcgcgtttt attcgtatga ttgaccaagt cttagaagcc cagcacgatt
     6121 tgtcaagcgt ggccgtcgca ccgccaaaag atgcagtaga gctcatgacc atccacaaga
     6181 gtaaagggct ggagtttcct tacgtcttta tcctcaatat ggatcaagat ttcaacaagc
     6241 aagactctat gtcagaagtc attctcagtc gtcagaatgg tcttggtgtc aaatatattg
     6301 ccaagatgga gacaggggca gtagaagacc actatcctaa aaccatcaaa ctctccattc
     6361 ctagtctgac ctataggcag aacgaagagg aattacagct agcaagctat tctgagcaga
     6421 tgcgtttgct gtatgttgct atgacgcggg ctgagaaaaa gctctatctt gtcggcaagg
     6481 gttctcgtga aaagctggaa gtcaagcaat acccagcagc caaaaatggg aaactaaata
     6541 gcaatactag actgcaagca cggaatttcc aagattggct ttgggctatc agtaaagtgt
     6601 ttactaagga caagctcaac tttagttatc gttttattgg cgaagatcag ttgaccagag
     6661 aagctatcgg agagttggaa accaagagtc ctctccaaga tagctcccaa gcagacaatc
     6721 gtcagtcaga taccatcaaa gaagctctgg aaatgctgaa ggaggtggaa gtttataata
     6781 ctcttcaccg cgcagctatt gaacttccta gtgttcaaac cccaagtcaa atcaagaaat
     6841 tctacgaacc agttatggat atggaaggtg tcgagattgc tggtcaaggt cagtcagtag
     6901 gcaagaaaat cagcttcgat ttgccagatt tttcaaccaa agaaaaggta actggagctg
     6961 agattggtag tgctactcac gaactcatgc agagaattga cctcagccag caactaaccc
     7021 ttgctagcct aacagaaaca ctcaaacaag ttcaaactag ccaagctgtc agagacaaga
     7081 tcaatcttga taaaattctt gctttctttg acacagtact cggtcaggaa attcttgcta
     7141 ataccgacca tctctatcgc gagcaacctt tctccatgct caaacgagac caaaagagtc
     7201 aggaagactt tgttgtccgt ggtatccttg atggctatct gctttacgaa aacaaaattg
     7261 ttctgttcga ctacaagaca gaccgctatg atgaaccaag tcaactcgta gaccgctatc
     7321 gtggtcagtt agctctatac gaagaggctt tatcacgagc ctattcgatt gaaaatattg
     7381 aaaaatactt gattttactc ggtaaagacg aggttcaagt tgtaaaagta taacttatac
     7441 tctttgaaaa tctcttcaaa ccacgtcagc ttcgccttgc tgt
//
LOCUS       DAVBOD010000078         7400 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 640-05
            SAMEA1012484-rid20186543.denovo.079, whole genome shotgun sequence.
ACCESSION   DAVBOD010000078 DAVBOD010000000
VERSION     DAVBOD010000078.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012484
            Sequence Read Archive: ERR059358
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7400)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7400)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979948.1
            Genome Coverage       :: 595x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:03:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,266
            CDSs (total)                      :: 2,219
            Genes (coding)                    :: 2,091
            CDSs (with protein)               :: 2,091
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 71 of 128
            Pseudo Genes (incomplete)         :: 50 of 128
            Pseudo Genes (internal stop)      :: 33 of 128
            Pseudo Genes (multiple problems)  :: 22 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7400
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012484-rid20186543.denovo.079"
                     /strain="NIG 640-05"
                     /db_xref="taxon:1313"
     gene            226..6657
                     /locus_tag="VQ862_001953"
     CDS             226..6657
                     /locus_tag="VQ862_001953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000750079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family serine peptidase"
                     /protein_id="HET3116243.1"
                     /translation="MKKSTVLSLTTAAVILAAYAPNEVVLADTSSSEDALSISDKEKV
                     VVDKETENKEKHKDIHNAIETSKDTEEKKTTIIEEKEVVSKNPVIDTKTSNEEARIKE
                     DSNQSQGDNAHSSANKGTENPKKEDRLVYIAEFKDKESGEKAIKGLSNLKNTKVLYTY
                     DRIFNGSAIETTPDNLDKIKQIEGISSVERAQKVQPMMNHARKEIGVEEAIDYLKSIN
                     APFGKNFDGRGMVISNIDTGTDYRHKAMRIDDDAKASMRFKKEDLKGTDKNYWLSDKI
                     PHAFNYYNGGKITVEKYDDGRDYFDPHGMHIAGILAGNDTEQDIKNFNGIDGIAPNAQ
                     IFSYKMYSDAGSGFAGDETMFHAIEDSIKHNVDVVSVSSGFTGTGLVGEKYWQAIRAL
                     RKAGIPMVVATGNYATSASSSSWDLVANNHLKMTDTGNVTRTAAHEDAIAVASAKNQT
                     VEFDKVNIGGESFKYRNIGAFFDKNKITTNEDGTKAPSKLKFVYIGKGQDQDLIGLDL
                     RGKIAVMDRIYTKDLKNAFKKAMDKGARAIMVVNTVNYYNRDNWTELPAMGYEADEGT
                     KSQVFSISGDDGVKLWNMINPNKKTEVKRNNKEDFKDKLEQYYPIDMESFNSNKPNVG
                     DEKEIDFKFAPDTDKELYKEDIIVPAGSTSWGPRIDLLLKPDVSAPGKNIKSTLNVIN
                     GKSTYGYMSGTSMATPIVAASTVLIRPKLKEMLERPVLKNLKGDDKIDLTSLTKIALQ
                     NTARPMMDATSWKEKSQYFASPRQQGAGLINVANALRNEVVATFKNTDSKGLVNSYGS
                     ISLKEIKGDKKYFTIKLHNTSNRPLTFKVSASAITTDSLTDRLKLDETYKDEKSPDGK
                     QIVPEIHPEKVKGANITFEHDTFTIGANSSFDLNAVINVGEAKNKNKFVESFIHFESV
                     EEMEALNSNGKKINFQPSLSMPLMGFAGNWNHEPILDKWAWEEGSRSKTLGGYDDDGK
                     PKIPGTLNKGIGGEHGIDKFNPAGVIQNRKDKNTTSLDQNPELFAFNNQGINAPSSSG
                     SKIANIYPLDSNGNPQDAQLERGLTPSPLVLRSAEEGLISIVNTNKEGENQRDLKVIS
                     REHFIRGILNSKSNDAKGIKSSKLKVWGDLKWDGLIYNPRGREENAPESKDNQDPATK
                     IRGQFEPIAEGQYFYKFKYRLTKDYPWQVSYIPVKIDNTAPKIVSVDFSNPEKIKLIT
                     KDTYHKVKDQYKNETLFARDQKEHPEKFDEIANEVWYAGAALVNEDGEVEKNLEVTYA
                     GEGQGRNRKLDKDGNTIYEIKGAGDLRGKIIEVIALDGSSNFTKIHRIKFANQADEKG
                     MISYYLVDPDQDSSKYQKLGEIAESKFKNLGNGKEGSLKKDTTGVEHHHQENEESIKE
                     KSSFTIDRNISTIRDFENKDLKKLIKKKYKEEDDFVTGGKRTVELDYKYDDKGNITAY
                     EDESALEYETEKFDEIKSKIYGVLSPSKDGHFEILGKISNVSKNAKVYYGNNYKFIEI
                     KATKYDSHSKTMIFDLYANINDIVDGLAFAGDMRLFVKDDNQIKAETKIRMPEKNKET
                     KAEYPYVSSYGNVIELGEGDLSKNKPDNLTKMESGKIYSDSEKQQYLLKDNIILRKGY
                     ALKVTTYNPGKTDMLEGNGVYSKEDIAKIQKANPNLRVLSETTIYADSRNVEDGRSTQ
                     AVLMSALDGFNIIRYQVFTFKMNDKGEAIDKDGNLVTDSSKLVLFGKDDKEYTGEDKS
                     NVEAIKEDGSMLFIDTKPVNLSMDKNYFNPSKSNKIYVRNPEFYLRGKISDKGGFNWE
                     LRVNESVVDNYLIYGDLHIDNTRDFNIKLNVKDGDIMDWGMKDYKANGFPDKVTDMDG
                     NVYLQTGYSDLNAKAVGVHYQFLYDNVKPEVNIDPKGNTSIEYADGKSVVFNINDKRN
                     NGFDGEIQEQHIYVNGKEYTSFDDIKQITDKTLNIKIVVKDFARNTTVKEFILNKDTG
                     EVSELKPHRVTVTIQNGKEMSSTIVSEEDFILPVYKGELEKGYQFDGWEISGFEGKKD
                     AGYVINLSKDTFIKPVFKKIEEKKEEENKPTFDVSKKKDNPQVNHSQLNESHRKEDLQ
                     REDHSQKSDSTKDVTATVLDKNNISSKSTTNNPNKLPKTGTASGAQTLLAAGIMFIVG
                     IFLGLKKKNQD"
     gene            complement(6953..7299)
                     /locus_tag="VQ862_001954"
                     /pseudo
     CDS             complement(6953..7299)
                     /locus_tag="VQ862_001954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014632353.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         2890 a          993 c         1428 g         2089 t
ORIGIN      
        1 taatcttatt ttttaacgtg tgctaaaaaa taaattaatg catgttaatt tttcttgaat
       61 taaatttttt taaatgatat actgttttta tggagagata acaattatat ataaatgtac
      121 tactctattt cctagataat acttagtaaa actttttata acaaaggcta gcaaagttaa
      181 agtttattat ctattggaag ttatataaat atgtaaggaa ttaaaatgaa aaaaagtaca
      241 gtattgtcat taactacagc tgcagttatt ttagcagcct atgcccctaa tgaggtagtc
      301 ttagcagaca catctagctc tgaagatgct ttaagcatct ctgataaaga aaaagtagta
      361 gtagataagg aaacagaaaa taaagagaaa cataaagata ttcataatgc tatagaaact
      421 tcaaaggata ctgaagaaaa gaaaacaaca attattgagg aaaaagaagt tgttagtaaa
      481 aatcctgtga tagacactaa aactagcaat gaagaagcaa gaatcaaaga agattccaat
      541 caatcccaag gagataatgc acactcgtct gcaaataaag gcacagaaaa tccgaaaaaa
      601 gaagatagac ttgtctatat tgctgaattt aaagataaag aatctggaga aaaagcaatc
      661 aagggactat caaatcttaa gaatacaaaa gttttatata cttatgatag aatttttaac
      721 ggtagtgcca tagaaacaac tccagataac ttggacaaaa ttaaacaaat agaaggtatt
      781 tcatcggttg aaagggcaca aaaagtccaa cccatgatga atcatgccag aaaggaaatt
      841 ggagttgagg aagctattga ttacctaaag tctatcaatg ctccatttgg gaaaaatttt
      901 gatggtagag gtatggtcat ttcaaatatc gatactggaa cagattatag acataaggct
      961 atgagaatcg atgatgatgc caaagcctca atgagattta aaaaagaaga cttaaaagga
     1021 actgataaaa attattggtt gagtgataaa atccctcatg cgttcaatta ttataatggt
     1081 ggcaaaatca ctgtagaaaa atatgatgat ggaagggatt attttgaccc acatgggatg
     1141 catattgcag ggattcttgc tggaaatgat actgaacaag atatcaaaaa ctttaacggc
     1201 atagatggaa ttgcacctaa tgcacaaatt ttctcttaca aaatgtattc tgacgcagga
     1261 tctgggtttg cgggtgatga aacaatgttt catgctattg aagattctat caaacacaac
     1321 gttgatgttg tttcggtatc atctggtttt acaggaacag gtcttgtagg tgagaaatat
     1381 tggcaagcta ttagggcatt aagaaaagca ggcattccaa tggttgtcgc tacgggtaac
     1441 tatgcgactt ctgcttcaag ttcttcatgg gatttagtag caaataatca tctgaaaatg
     1501 accgacactg gaaatgtaac acgaactgca gcacatgagg atgcgatagc ggtcgcttct
     1561 gctaaaaatc aaacagttga gtttgataaa gttaacatag gtggagaaag ttttaaatac
     1621 agaaatatag gggccttttt cgataagaat aaaatcacaa caaatgaaga tggaacaaaa
     1681 gctcctagta aattaaaatt tgtatatata ggcaaggggc aagaccaaga tttgataggt
     1741 ttggatctta ggggcaaaat tgcagtaatg gatagaattt atacaaagga tttaaaaaat
     1801 gcttttaaaa aagctatgga taagggtgca cgcgccatta tggttgtaaa tactgtaaat
     1861 tactacaata gagataattg gacagagctt ccagctatgg gatatgaagc ggatgaaggt
     1921 actaaaagtc aagtgttttc aatttcagga gatgatggtg taaagctatg gaacatgatt
     1981 aatcctaata aaaaaactga agtcaaaaga aataataaag aagattttaa agataaattg
     2041 gagcaatact atccaattga tatggaaagt tttaattcca acaaaccgaa tgtaggtgac
     2101 gaaaaagaga ttgactttaa gtttgcacct gacacagaca aagaactcta taaagaagat
     2161 atcatcgttc cagcaggatc tacatcttgg gggccaagaa tagatttact tttaaaaccc
     2221 gatgtttcag cacctggtaa aaatattaaa tccacgctta atgttattaa tggcaaatca
     2281 acttatggct atatgtcagg aactagtatg gcgactccaa tcgtggcagc ttctactgtt
     2341 ttgattagac cgaaattaaa ggaaatgctt gaaagacctg tattgaaaaa tcttaaggga
     2401 gatgacaaaa tagatcttac aagtcttaca aaaattgccc tacaaaatac tgcgcgacct
     2461 atgatggatg caacttcttg gaaagaaaaa agtcaatact ttgcatcacc tagacaacag
     2521 ggagcaggcc taattaatgt ggccaatgct ttgagaaatg aagttgtagc aactttcaaa
     2581 aacacggatt ctaaaggttt ggtaaactca tatggttcca tttctcttaa agaaataaaa
     2641 ggtgataaaa aatactttac aatcaagctt cacaatacat caaacagacc tttgactttt
     2701 aaagtttcag catcagcgat aactacagat tctctaactg acagattaaa acttgatgaa
     2761 acatataaag atgaaaaatc tccagatggt aagcaaattg ttccagaaat tcacccagaa
     2821 aaagtcaaag gagcaaatat cacatttgag catgatactt tcactatagg cgcaaattct
     2881 agctttgatt tgaatgcggt tataaatgtt ggagaggcca aaaacaaaaa taaatttgta
     2941 gaatcattta ttcattttga gtcagtggaa gaaatggaag ctctaaactc caacgggaag
     3001 aaaataaact tccaaccttc tttgtcgatg cctctaatgg gatttgctgg gaattggaac
     3061 cacgaaccaa tccttgataa atgggcttgg gaagaagggt caagatcaaa aacactggga
     3121 ggttatgatg atgatggtaa accgaaaatt ccaggaacct taaataaggg aattggtgga
     3181 gaacatggta tagataaatt taatccagca ggagttatac aaaatagaaa agataaaaat
     3241 acaacatccc tggatcaaaa tccagaatta tttgctttca ataaccaagg gatcaacgct
     3301 ccatcatcaa gtggttctaa gattgctaac atttatcctt tagattcaaa tggaaatcct
     3361 caagatgctc aacttgaaag aggattaaca ccttctccac ttgtattaag aagtgcagaa
     3421 gaaggattga tttcaatagt aaatacaaat aaagagggag aaaatcaaag agacttaaaa
     3481 gtcatttcga gagaacactt tattagagga attttaaatt ctaaaagcaa tgatgcaaag
     3541 ggaatcaaat catctaaact aaaagtttgg ggtgacttga agtgggatgg actcatctat
     3601 aatcctagag gtagagaaga aaatgcacca gaaagtaagg ataatcaaga tcctgctact
     3661 aagataagag gtcaatttga accgattgcg gaaggtcaat atttctataa atttaaatat
     3721 agattaacta aagattaccc atggcaggtt tcctatattc ctgtaaaaat tgataacacc
     3781 gcccctaaga ttgtttcggt tgatttttca aatcctgaaa aaattaagtt gattacaaag
     3841 gatacttatc ataaggtaaa agatcagtat aagaatgaaa cgctatttgc gagagatcaa
     3901 aaagaacatc ctgaaaaatt tgacgagatt gcgaacgaag tttggtatgc tggcgccgct
     3961 cttgttaatg aagatggaga ggttgaaaaa aatcttgaag taacttacgc aggtgagggt
     4021 caaggaagaa atagaaaact tgacaaagac ggaaatacca tttatgaaat taaaggtgcg
     4081 ggagatttaa ggggaaaaat cattgaagtc attgcattag atggttctag caatttcaca
     4141 aagattcata gaattaaatt tgctaatcag gctgatgaaa aggggatgat ttcctattat
     4201 ctagtagatc ctgatcaaga ttcatctaaa tatcaaaagc ttggcgagat tgcagaatct
     4261 aaatttaaaa atttaggaaa tggaaaagag ggtagtctaa aaaaagatac aactggggta
     4321 gaacatcatc atcaagaaaa tgaagagtct attaaagaaa aatctagttt tactattgat
     4381 agaaatattt caacaattag agactttgaa aataaagacc taaagaaact cattaaaaag
     4441 aaatataagg aagaagacga ctttgtaact ggtggaaaaa gaacagtaga acttgattat
     4501 aaatatgacg ataaaggaaa tataactgcc tatgaagatg aaagtgctct agaatatgaa
     4561 actgaaaaat ttgacgaaat aaaatcaaaa atttatggtg ttctaagccc atctaaagat
     4621 ggacactttg aaattcttgg aaagataagc aatgtttcta aaaatgccaa ggtatattat
     4681 ggaaataact ataaatttat agaaatcaaa gcgactaagt atgactcaca ttcaaaaacg
     4741 atgatatttg atttatacgc taatattaat gatattgtag atggattagc ttttgctgga
     4801 gatatgagat tatttgttaa agatgacaat caaataaaag ctgaaactaa aattagaatg
     4861 cctgaaaaaa ataaggaaac taaagcagaa tatccgtatg tatcaagtta tgggaatgta
     4921 atcgaattag gagaaggaga cctttcaaaa aacaaaccag acaatttaac taaaatggaa
     4981 tctggtaaaa tctattctga ttcagaaaaa caacaatatc tgttaaagga taacatcatt
     5041 ctaagaaaag gctatgcact aaaagtgact acctataatc ctggaaaaac ggatatgtta
     5101 gaaggaaatg gagtctatag caaggaagat atagcaaaaa tacaaaaggc caatcctaat
     5161 ctaagagtcc tttcagaaac aacaatttat gctgatagta gaaatgttga agatggaaga
     5221 agtacccaag ctgtattaat gtcggctttg gacggcttta acattataag gtatcaagtg
     5281 tttacattta aaatgaacga taaaggggaa gctatcgata aagacggaaa tcttgtgaca
     5341 gattcttcta aacttgtatt atttggtaag gatgataaag aatacactgg agaggataag
     5401 tccaatgtag aagctataaa agaagatggc tccatgttat ttattgatac caaaccagta
     5461 aacctttcaa tggataagaa ctactttaat ccatctaaat ctaataaaat ttatgtacga
     5521 aatccagaat tttatttaag aggtaagatt tctgataagg gtggttttaa ctgggaattg
     5581 agagttaatg aatcggttgt agataattat ttaatctacg gagatttaca cattgataac
     5641 actagagatt ttaatattaa gctgaatgtt aaagacggtg acatcatgga ctggggaatg
     5701 aaagactata aagcaaacgg atttccagat aaggtaacag atatggatgg aaatgtttat
     5761 cttcaaactg gctatagcga tttgaatgct aaagcagttg gagtccacta tcagttttta
     5821 tatgataatg ttaaacccga agtaaacatt gatcctaagg gaaatactag tatcgaatat
     5881 gctgatggaa aatctgtagt ctttaacatc aatgataaaa gaaataatgg attcgatggt
     5941 gagattcaag aacaacatat ttatgtaaat ggaaaagaat atacatcatt tgatgatatt
     6001 aaacaaataa cagacaagac actaaacatt aagattgttg taaaagattt tgcaagaaat
     6061 acaaccgtaa aagaattcat tttaaataaa gatacgggag aggtaagtga attaaaacct
     6121 catagggtaa ctgtgaccat tcaaaatgga aaagaaatga gttcaacgat agtgtcggaa
     6181 gaagatttta ttttacctgt ttataagggt gaattagaaa aaggatacca atttgatggt
     6241 tgggaaattt ctggtttcga aggtaaaaaa gacgctggct atgttattaa tctatcaaaa
     6301 gataccttta taaaacctgt attcaagaaa atagaggaga aaaaggagga agaaaataaa
     6361 cctacttttg atgtatcgaa aaagaaagat aacccacaag taaaccatag tcaattaaat
     6421 gaaagtcaca gaaaagagga tttacaaaga gaagatcatt cacaaaaatc tgattcaact
     6481 aaggatgtta cagctacagt tcttgataaa aacaatatca gtagtaaatc aactactaac
     6541 aatcctaata agttgccaaa aactggaaca gcaagcggag cccagacact attagctgcc
     6601 ggaataatgt ttatagtagg aatttttctt ggattgaaga aaaaaaatca agattaagat
     6661 aaaagctata gaaaaaaatg gtttatgtac tgagattaga tagtgaggtg atgacatagt
     6721 tttgtgaaaa tagccattta taactcaatt atttagttta ctttacttta ctagtgatac
     6781 tatttggagt tattaatgga cttagtttat ataactaatg aattgattga aagggttagt
     6841 attgacaata ttggtcatat tgactagaaa atagagtcta tcaaaattta aaggctaata
     6901 gaggtgatga gacaatttcg gctctttgtc aactgtagtg ggttgaagtc agctaagctc
     6961 gagaaaggac aaattttgtc ctttcttttt tgatattcag agcgatgaaa atccgttttt
     7021 tgaagttttc aaagtttcga aaaccaaagg cattgcgctt gataagtttg atgagattat
     7081 tggtcgcttc cagtttggca ttagaatagt gtagttgaag ggcattgaca atcttctctt
     7141 tatctttgag gaaggtttta gaggatgaac ttgattcaga ttgtcctcaa tgagtccgaa
     7201 aaatttgtca ggctccttat tctgaaagtg aaaaagcaag agttgataga gattatagtg
     7261 gtgtttcaag tcttctgaat agctcaaaag tttatctata gtagattgaa actagaatag
     7321 tacacctctg cttctaaaac attgttagaa atcgatttga ctgtcctgaa tgatttgtcc
     7381 tgttattatt tcattttact
//
LOCUS       DAVBOD010000079         6938 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 640-05
            SAMEA1012484-rid20186543.denovo.080, whole genome shotgun sequence.
ACCESSION   DAVBOD010000079 DAVBOD010000000
VERSION     DAVBOD010000079.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012484
            Sequence Read Archive: ERR059358
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6938)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6938)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979948.1
            Genome Coverage       :: 595x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:03:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,266
            CDSs (total)                      :: 2,219
            Genes (coding)                    :: 2,091
            CDSs (with protein)               :: 2,091
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 71 of 128
            Pseudo Genes (incomplete)         :: 50 of 128
            Pseudo Genes (internal stop)      :: 33 of 128
            Pseudo Genes (multiple problems)  :: 22 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6938
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012484-rid20186543.denovo.080"
                     /strain="NIG 640-05"
                     /db_xref="taxon:1313"
     gene            complement(57..287)
                     /locus_tag="VQ862_001955"
     CDS             complement(57..287)
                     /locus_tag="VQ862_001955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000832182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3116244.1"
                     /translation="MKRVILVAVIQAVVLFFIIGALAYAFKGDFFYNYLAVVFAPIAG
                     VLRFGTAYITEIVLPRKAAEIAEKRKAGKNSK"
     gene            complement(305..946)
                     /locus_tag="VQ862_001956"
     CDS             complement(305..946)
                     /locus_tag="VQ862_001956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET3116245.1"
                     /translation="MKLLKNLGWILLALLSFLFIYGFIQGLATASLALGASPYAVTLL
                     YVALAGVYVYGIYKWYQKAPVHIEKSGFNRFIWLPVLVWFLSLVVQFFLPDDPSVNQQ
                     IATDLTLSQPLFSFFAVVIFAPLTEEIVFRGMLARYLFPKQDNSKRTLIFLLVSSLLF
                     ALIHFPGDVQQFFVYFSLGFSLGLAYISRKGLVYSISLHALNNLVGFLMILML"
     gene            complement(958..1692)
                     /locus_tag="VQ862_001957"
     CDS             complement(958..1692)
                     /locus_tag="VQ862_001957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3169 family protein"
                     /protein_id="HET3116246.1"
                     /translation="MKKKRRLLFLMSIVLGGFLGMFVGMFKARVESHEIILDVKALMP
                     WISAICLLIGFISMFLTFNFLKKSRKFHSLYQEEMDDDLNETYYVQMYRNLEFGTIAF
                     NITGVAIPLAIFISLSEVIILHTNPQTFFLSFLLFVVFLVAQKSLFKTIAIVRQFDLE
                     FFATPKDVLNYINSYDEGERQANLEQSFRILFQLHQYVLPALYIFLIIISFLTGEIQL
                     LAFLLVGAIHVYINVMQLPMVKRYFK"
     gene            complement(1695..1892)
                     /locus_tag="VQ862_001958"
     CDS             complement(1695..1892)
                     /locus_tag="VQ862_001958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001046145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3116247.1"
                     /translation="MNKYKVIYYVVVIALLVSVFLLIGMDLSWFNPYQSDQFVWVYFA
                     LIPVTEWIEKKSKNLASEKGE"
     gene            complement(1892..2098)
                     /locus_tag="VQ862_001959"
     CDS             complement(1892..2098)
                     /locus_tag="VQ862_001959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001176227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET3116248.1"
                     /translation="MQLKNRLKELRARDGLNQTDLAKLAGVSRQTISLLERDEYTPSI
                     IIALKISQIFNETVESVFRLEEDE"
     gene            complement(2108..2422)
                     /locus_tag="VQ862_001960"
     CDS             complement(2108..2422)
                     /locus_tag="VQ862_001960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3116249.1"
                     /translation="MWVLGFILFMIFFYSNNSKKIKKLENKIKKLERKEKGNAEMSRL
                     LQEMIGKEPIITGVYIGPDNWEVVDVDEEWVKLRSVDNTGKEKFKLQRIEDIQTVEFD
                     GE"
     gene            complement(2647..2727)
                     /locus_tag="VQ862_001961"
                     /pseudo
     CDS             complement(2647..2727)
                     /locus_tag="VQ862_001961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(2718..4007)
                     /locus_tag="VQ862_001962"
     CDS             complement(2718..4007)
                     /locus_tag="VQ862_001962"
                     /EC_number="6.1.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine--tRNA ligase"
                     /protein_id="HET3116250.1"
                     /translation="MKLQKPKGTQDILPAESAKWQYVEGFAREIFKRYNYAEVRTPIF
                     EHYEVISRSVGDTTDIVTKEMYDFYDKGDRHITLRPEGTAPVVRAYVENKLFAPEVQK
                     PSKFYYMGPMFRYERPQAGRLRQFHQIGVECFGSSNPATDVETIVMAAHFLKEIGIQG
                     VKLHLNTLGNPESRAAYRQALIDYLTPLKETLSKDSQRRLEENPLRVLDSKEKEDKVA
                     VENAPSILDFLDEESQTHFDAVSQMLENLGVDYIIDTNMVRGLDYYNHTIFEFITEIE
                     GNDLTVCAGGRYDGLVAYFGGPETAGFGFGLGVERLLLILEKQGVALPIENALDVYIA
                     VLGDGANVKALELVQALRQQGFKAERDYLNRKLKAQFKSADVFAAKTLITLGESEVES
                     RQVTVKNNQTREEVQVSLETISQNFSEIFEKLGFYTQ"
     gene            complement(4104..5333)
                     /locus_tag="VQ862_001963"
     CDS             complement(4104..5333)
                     /locus_tag="VQ862_001963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter"
                     /protein_id="HET3116251.1"
                     /translation="MKLLFRNPAYRILTLSRFFNAFGASIFNLVFIVYASTLSQASFA
                     VAMANIVMILPTLFTVFAGIRADYTRDKVKWMVYSGLFQAVLFFLAALVVQQASLFAF
                     SILCLINVISDIISDFAGGLRMPLIKEKVAEDDLMEAYSFSQFITYISAIGGQAFGVW
                     LLALSVNNFSLVAGINACFFLVSATILFLGKSKLSLSMSSADGENLKNEKLSIKDQFL
                     TIYRNLRLVFLKSGQKNFGFMLFAVLLINSLGGALGGIYNIFFLSHSLLNFSYTEALF
                     INQFCVLVAVIISSLTGNDYFGKQSLPRLMMWATVGLSLVGLANLFNQVVLGLLFLFF
                     TLYVSGKVQPKISAMLMKNLAPEVLARTSNFLGLLFTLSIPVGTACFSLVAVWNIQLT
                     WMLFVGLSLLAIFFDNS"
     gene            complement(5526..6377)
                     /gene="rgg"
                     /locus_tag="VQ862_001964"
     CDS             complement(5526..6377)
                     /gene="rgg"
                     /locus_tag="VQ862_001964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000434947.1"
                     /note="Rgg, as the term is used in Streptococcus
                     pneumoniae, is the lone quorum-sensing system
                     transcriptional regulator related to proteins Rgg1, Rgg2,
                     Rgg3, and Rgg4 of Streptococcus pyogenes; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quorum-sensing system transcriptional regulator
                     Rgg"
                     /protein_id="HET3116252.1"
                     /translation="MEQIGKVFRQLRESRNISLRQATGGQFSPSMLSRFETGQSELLV
                     EKFLFALENISASVEEILFLARGFQYDTDSELRKEITDVLEPKNIAPLEDLYRREYQK
                     HAHSHNKQKHILNAIIIKSYMKSIDERVDLTAEEGKVLHDYLFSTEIWGIYELNLFSV
                     SSPFLSVSLFTRYVREMVRKSDFLMEMSGNRNLFHTILLNGFLASIECEEFTNAYYFK
                     RVIEEHFYKENETYFRIVYLWAEGLLDSKQGRVKEGQKKMEDAVRIFEMLGCNKSAEY
                     YRNTTEC"
     gene            6501..6842
                     /locus_tag="VQ862_001965"
     CDS             6501..6842
                     /locus_tag="VQ862_001965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003080443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HET3116253.1"
                     /translation="MRDDIKINDRALALQDQIIEKLEKVFDTDVELDVYNLGLIYEIN
                     LDETGLCKIVMTFTDTACDCAESLPIEIVAGLKQIEGIKDIKVEVTWSPAWKITRISR
                     YGRIALGLPPR"
BASE COUNT         2249 a         1441 c         1274 g         1974 t
ORIGIN      
        1 ctctttgatt ttcattgagt ataatacaaa aatccgatga acttcaccgg actcttttat
       61 tttgaatttt tgcctgcttt acgcttttca gcgatttcgg ctgcctttcg aggcaagaca
      121 atttccgtta tgtaagccgt cccaaaacgc agtacacctg caataggagc aaagacaact
      181 gctagatagt tatagaagaa atcgcctttg aaggcataag ctagcgctcc aatgatgaaa
      241 aatagaacga ctgcctgaat cactgctact aaaattactc gtttcatgtg acctcctgac
      301 tctattatag catgagaatc atcaaaaagc cgactaaatt attcaaagcg tgaagagaaa
      361 tactgtagac cagacctttt ctgctaatgt aagccaaacc caaactaaaa ccaaggctaa
      421 aatagacaaa aaattgttgc acatcacctg gaaaatgaat caaggcaaat agaagactag
      481 ataccagaag aaaaatcagg gttcgtttac tattgtcctg cttaggaaag agatagcgtg
      541 ctaacatccc tctaaaaaca atctcttccg tcaaaggagc aaaaataacc acagcaaaga
      601 atgagaaaag tggttgagac aaggtcaagt ctgtcgctat ttgttgattt actgaaggat
      661 catctggcaa gaagaattga acgaccagag ataagaacca aaccaagaca ggaagccaaa
      721 taaatcgatt aaagccgctc ttctcaatat gaacaggagc cttctgatac catttgtaaa
      781 tgccgtacac atatactcca gccaaggcca catagagtag agtaacagca tagggtgaag
      841 cgcctaaagc aagcgacgca gtcgcgagcc cctgaataaa gccatagata aataaaaagg
      901 atagaagggc tagaagaatc cagccaaggt ttttaagtaa tttcatagat aactccttta
      961 tttgaaataa cgttttacca taggtaactg catcacattg atataaacat ggatggctcc
     1021 tacaagcaag aaagctagta actgaatctc tcctgtcaag aaagaaatga taataagaaa
     1081 aatatataag gctggtaaga catattggtg taattggaat aaaattcgaa aactctgttc
     1141 caaattagcc tgacgctccc cttcatcata agaatttata tagttcaaga catcctttgg
     1201 tgtagcgaaa aattccaaat caaactgacg aacaatcgca atggttttaa aaagagattt
     1261 ttgagcgact aagaatacca caaagagtaa gaaagaaagg aaaaatgttt gagggtttgt
     1321 atgcaatata atcacctcac ttaatgaaat aaaaatagcc aatggaatcg ctacacctgt
     1381 aatattaaaa gcaatggttc caaactcaag attccgatac atttgcacat aataggtttc
     1441 attcagatcg tcatccattt cctcttgata caaggaatga aattttctgc ttttctttaa
     1501 gaaattgaaa gtcaaaaaca tactaatgaa acctatcagt aaacaaatag ctgatatcca
     1561 tggcatcaag gcttttacat ctaaaataat ttcgtgggat tcgacacgtg ccttaaacat
     1621 ccctacaaac atgcccaaga acccccccaa gacaatagac atcaaaaata acaatctacg
     1681 tttctttttc atattcattc tcctttttca cttgctagat ttttggattt cttttcaatc
     1741 cattcagtta ctgggatgag agcaaagtag acccaaacaa attggtcgct ttgataggga
     1801 ttaaaccagc ttaggtccat cccaatcagt agaaatacgc tgactaataa agctatgacc
     1861 actacataat aaatcacttt atacttgttc atcactcgtc ctcctccaaa cgaaataccg
     1921 attcgactgt ttcgttgaaa atttgagata ttttcagggc aatgataatg gatggggtgt
     1981 actcatcccg ttctagtagg ctaatggtct gtctggaaac ccctgccagt ttggctaggt
     2041 cggtttgatt gagaccatcg cgagctcgaa gctcttttag acgatttttt agttgcacgt
     2101 tacacaccta ctctccgtca aattcaacgg tttggatatc ttcaatacgt tgcaacttga
     2161 atttttcttt tcccgtatta tcaacactac gtagtttgac ccattcctca tcaacatcca
     2221 caacttccca gttatctggc ccaatataca ctcccgttat aattggttcc tttccaatca
     2281 tttcttgtaa taatctcgac atttctgcgt ttcctttctc ttttcgctca agttttttga
     2341 ttttattctc tagtttcttg atttttttag aattattaga ataaaagaaa atcataaata
     2401 gtataaatcc tagtacccac attataactc ctttctgctt cctatttctt aacttgaatt
     2461 cattgtaaca tatctttttc tttttgacaa ttatagttgt caaaaagttt atgatttttg
     2521 tcattttgca aaagaaaaag gtcaggagta agttcctgac cactttatct atcattaata
     2581 ctcttctaaa atctcttcaa accacgtcag cttcaccttg ccgtaggcat ggttactgac
     2641 ttcgtcagtt tcatctacaa cctcaaaacc atgttttgag caacctgcgg ctagcttcct
     2701 agtttgctct ttgattttca ttgagtataa aatcctagtt tttcaaagat ttctgagaag
     2761 ttttggctga ttgtctcaag tgacacttgc acttcttctc gggtttggtt gttcttgact
     2821 gtcacttgtc tgctttcgac ttcgctctct cctagggtga tgagggtctt agccgcaaag
     2881 acatcggctg acttgaactg agctttgagc ttacggttga ggtaatcacg ctctgctttg
     2941 aaaccttgtt ggcgaagagc ttggactagt tctagggctt tgacatttgc tccatcaccc
     3001 aagactgcga tatagacatc tagggcattt tcgataggga gggccacgcc ttgtttttca
     3061 aggatgagaa gcaggcgctc tacaccaagc ccaaaaccaa atccagcagt ttcagggcct
     3121 ccaaagtaag caaccaaacc atcgtagcga ccacccgcac agactgtcaa gtcattgccc
     3181 tcaatctctg tgataaactc gaaaatggtg tggttgtagt agtccagacc acgcaccata
     3241 ttggtatcga tgatgtaatc tactccaaga ttttccaaca tctgactcac agcatcaaaa
     3301 tgagtttggc tttcttcatc aagaaagtcc aagatagacg gcgcattctc tactgccacc
     3361 ttgtcttctt tttccttaga gtccaagaca cgaagaggat tttcctccaa gcgacgttgg
     3421 ctatccttag acaaggtctc cttgagcggt gtcaaatagt caatcaaggc ttggcggtag
     3481 gctgcacggc tctcaggatt tccaagagtg ttgaggtgca atttgacacc ttgaataccg
     3541 atttccttca aaaaatgggc tgccataacg attgtttcca catcggtagc tggattgcta
     3601 gaaccaaaac actcaacacc aatctggtgg aattggcgca agcgccctgc ctgtggacgc
     3661 tcataacgga acataggtcc catgtagtag aacttgcttg gcttttgcac ttctggagcg
     3721 aagagtttat tttccacata ggcacggaca acgggcgcag ttccttctgg acggagggta
     3781 atatggcggt cacccttgtc atagaaatcg tacatttcct tggttacaat atctgttgta
     3841 tctccgacag agcggctgat aacctcgtaa tgctcgaaaa taggcgtacg cacttctgcg
     3901 tagttgtagc gcttgaaaat ttcacgggca aagccctcaa cgtactgcca cttagcagac
     3961 tcagcaggta aaatatcctg cgttcctttt ggtttttgta atttcatagg gaatcctctt
     4021 taaacttaat agtcttattt taccataaat agagggatta aaacagtaag aaaaaaatta
     4081 ggatttagat atcatttttg agattaagaa ttgtcaaaaa aaatagctag caaggaaaga
     4141 ccaacaaata gcatccaagt caactgtata ttccatacgg ctactagtga aaaacaagct
     4201 gttcccacag gtatggataa ggtaaacaat agacctaaaa aattactagt acgagctaga
     4261 acctctggag ctagattttt catgagcatg gcactaatct ttggttgaac tttaccagac
     4321 acatacagag taaagaagag aaatagcaaa ccaagcacga cttgattgaa taaattagcc
     4381 aaaccaacta gactaagccc tacggtcgcc cacatcatca atctaggcaa ggactgcttc
     4441 ccaaaataat cattgcccgt aaggctactg atgatgactg ctactaaaac acagaattga
     4501 ttgataaata gtgcctctgt ataagaaaaa ttcaagagag aatggctcaa aaagaagata
     4561 ttataaattc cacccaaagc gccacccaag gaattaataa gcaagacagc aaagagcata
     4621 aaaccaaagt ttttctgtcc acttttaaga aaaacgagac gtaaatttcg gtaaattgtt
     4681 aggaactggt ctttgataga aagcttctca ttttttaagt tttcaccatc agcagatgac
     4741 attgacaggc tcaatttgct ttttcctaaa aagaggatag tggctgatac taggaaaaag
     4801 caggcattga ttcccgcaac gagagaaaaa ttgttgaccg atagagctaa gagccagact
     4861 ccgaaagctt gaccaccaat agctgaaata taggtgatga actgtgaaaa agaataagcc
     4921 tccatcagat catcttcagc tactttttcc ttaataagag gcatacgcag gccacctgca
     4981 aaatcactga tgatatcact aatgacattg atcaaacaca ggatagaaaa ggcaaagaga
     5041 ctagcttgct gaacaactag ggctgctaga aaaaatagaa ccgcctgaaa caaaccgcta
     5101 tagaccatcc atttgacctt gtccctcgtg taatctgccc gaatccctgc aaaaactgta
     5161 aagagggtcg gaagaatcat gacaatattc gccatagcaa cagcaaaaga tgcttgtgac
     5221 aaggtcgatg catagacgat aaagaccagg ttgaaaatcg aagcaccaaa agcattgaag
     5281 aagcgtgata aagtcaaaat tctataagct ggatttctaa acaatagttt catagataat
     5341 ctcccttctt gttcgaacct ctatatgaag tatgactata gtatagcact tagaaatttg
     5401 agagggagaa ctcttgaata tatgcaacaa ataaaatgag caaaaagaaa cgatagaact
     5461 tttgtaatga cctgagagag ggcaatagtt ctatcgcttc aaattttttc ttggtttgca
     5521 gatattcaac attcggtcgt atttctatag tattcggcag atttattaca gccaagcatc
     5581 tcaaaaatac ggacagcatc ctccatcttt ttctggcctt ccttgactct accttgcttg
     5641 ctatcaagga gaccttctgc ccacagataa acaattcgga aataggtctc attttccttg
     5701 tagaaatgct cttcgataac acgtttaaaa taataggcat tggtaaattc ttcacactca
     5761 atactagcta aaaagccgtt caatagtata gtatgaaaaa ggtttcgatt gccagacatt
     5821 tccattagaa aatcagattt acgtaccatt tctcgtacat atctagtaaa aagagaaaca
     5881 gataaaaatg gagaactgac tgaaaataaa ttgagttcat agattcccca gatctcggta
     5941 gaaaacaaat aatcatgaag gacttttcct tcctctgctg ttaagtctac cctttcatct
     6001 atgctcttca tataagactt gataataatg gcatttagaa tatgtttctg tttgttgtga
     6061 gaatgggcat gcttttgata ctccctgcga tataagtcct caagaggtgc tatattcttt
     6121 ggttccaaga catctgtaat ttcttttctc aactcagaat ctgtatcata ctggaaacct
     6181 ctcgccagaa agaggatctc ctccacactg gcagatatat tttccagagc aaatagaaac
     6241 ttttccacca aaagctcact ctgacctgtt tcaaaacggg acaacataga cggcgaaaat
     6301 tgtcctccgg ttgcttgtct cagtgagata tttcttgact ctcgtaattg tctaaagact
     6361 tttccaatct gctccataga cttccccttg attccgtatt ttcttcattt tatcatattt
     6421 ttcagaaaat taatcaaaag cttgccaaat tgtcagaatt atgagaaaat agaggatatt
     6481 tatcacatgg agggactgct atgagagacg atatcaaaat caatgaccgt gctttggcct
     6541 tgcaagacca aattatcgaa aaactagaga aagtttttga tacagatgtg gaattggatg
     6601 tttacaatct aggtctgatt tatgaaatca atctggatga aacggggctc tgcaagattg
     6661 tcatgacctt caccgatact gcctgtgatt gcgccgaaag cctgcctatt gaaattgtgg
     6721 caggtctgaa acaaatcgag ggtatcaaag atatcaaggt tgaagttacc tggtcgcctg
     6781 cttggaaaat cacacgaatc agtcgctatg gccgtattgc ccttggacta ccacctcgtt
     6841 aagcaggcca atcactttta aagatgaaaa aagcaagccg aaaatggctt gctttttgat
     6901 actcaatgaa aatcaaaggg caaactagaa aactagcc
//
LOCUS       DAVBOD010000080         6853 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 640-05
            SAMEA1012484-rid20186543.denovo.081, whole genome shotgun sequence.
ACCESSION   DAVBOD010000080 DAVBOD010000000
VERSION     DAVBOD010000080.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012484
            Sequence Read Archive: ERR059358
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6853)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6853)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979948.1
            Genome Coverage       :: 595x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:03:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,266
            CDSs (total)                      :: 2,219
            Genes (coding)                    :: 2,091
            CDSs (with protein)               :: 2,091
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 71 of 128
            Pseudo Genes (incomplete)         :: 50 of 128
            Pseudo Genes (internal stop)      :: 33 of 128
            Pseudo Genes (multiple problems)  :: 22 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6853
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012484-rid20186543.denovo.081"
                     /strain="NIG 640-05"
                     /db_xref="taxon:1313"
     gene            <1..180
                     /locus_tag="VQ862_001966"
     CDS             <1..180
                     /locus_tag="VQ862_001966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015973630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3116254.1"
                     /translation="RGYNHAYERGREAQRQEIRKNIRREFKGFTFDNEPPVGLRPEPL
                     ALPEPRRARYANRMG"
     gene            161..352
                     /locus_tag="VQ862_001967"
     CDS             161..352
                     /locus_tag="VQ862_001967"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3116255.1"
                     /translation="MQIVWDRQAWDLFTCKRREKMRDLEMMAHMQHEIDDLKKQLQQE
                     QSLRKRLEAENFQLKLRRK"
     gene            487..828
                     /locus_tag="VQ862_001968"
     CDS             487..828
                     /locus_tag="VQ862_001968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000189404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3116256.1"
                     /translation="MTQAERIRKYYKDHPTASYDEVAEVVGTSNSNVRVNLFKDLKAG
                     RCVRLEDESIDYSPYFNHKKSLTELFDWKNDTRREWVDMLTRAAEKETDSNVMRLLIK
                     EANKLMKEVTK"
     gene            825..1301
                     /locus_tag="VQ862_001969"
     CDS             825..1301
                     /locus_tag="VQ862_001969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000157809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siphovirus Gp157 family protein"
                     /protein_id="HET3116257.1"
                     /translation="MTKSLYAIVGQFLEIYNMELDEETKLDTLDSIDWETDYETKVEN
                     CIKVVKNIDADMEARDAEIKRLTNLNKFDKKKKEYLKERVSESMKLTGHERVDTPLFK
                     VSFRKSQAVEVNEAVLPEVYKVATWKPDKKLLKEDLKNGLEIIGASLVERKNLSIR"
     gene            1298..1999
                     /locus_tag="VQ862_001970"
     CDS             1298..1999
                     /locus_tag="VQ862_001970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000704952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HET3116258.1"
                     /translation="MKITKATEITNDDACYLIYGNPGFGKTTTISFIPGKTLIINIDK
                     SAKVLAGNPNIDIADVDTHKIWDEWLTVVKELLQGAGKPYDTIVVDNVSELFRACLAN
                     LGRDGKNHRVPTQADYQRVDFTILDSLRALLQLNKRIVFTAWETSDQWSDENGMIYNR
                     AMPDIRSKILNNFLGLTDVVARLVKKTTDDGEEVRGFILQPSASVYAKNRLDDRKGCK
                     VDELFAQRLPEGTDN"
     gene            1956..3365
                     /locus_tag="VQ862_001971"
     CDS             1956..3365
                     /locus_tag="VQ862_001971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012972453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HET3116259.1"
                     /translation="MSFSLRDYQKELIIDVIKSMKAGNRKIMVQSPPRSGKTVVMSYI
                     AKNATDKDKTVLFFSHRKEINEQVHEAFKRGGVNLDKVIIGTVGSIVRKLERLPQVDV
                     ILVDEAHHIKAKQYQTILNYFSNATQLFFTGTPIRLDGSGFHDLADDLVVGKSILWLQ
                     DHGNIAEFDYYSINLLDMAKLKKRSGEFTNHSIDVAFDSKATYGDYIDHYERLAKGKQ
                     AIVYTHSVEYAERVAKRFLEQGYQSAVVSGKTPQGERESHMQAFREGKLTIMVNVNLF
                     TEGIDLPNVDVCIMLRPTDSLSLYLQFAMRALNPREGKKAILIDHVGNHIRHGLPNDD
                     REWTLDGTKKKKKSSERSTVTCEKCFATFWREQLVDGCCPYCKAEIVEKKNIQDIKQD
                     KSDIQLTKINQGMEFITIRGKEIEVKTEEAKVYRRVKTYGKRYTRCQNLSELKAFRLL
                     NGYQPGWLWHKQKELNLWR"
     gene            3371..3853
                     /locus_tag="VQ862_001972"
     CDS             3371..3853
                     /locus_tag="VQ862_001972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001173389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF669 domain-containing protein"
                     /protein_id="HET3116260.1"
                     /translation="MALFSVNYEAAEQFSSIEDGTYEVVVAQAEQSASQSGTDFLDIR
                     LKIRDDFQQKFRNNLIFDKVWINKQTLQYPEWALQRYSKAVKIPEGVEVNTIEQFLGL
                     IIGKTLKVTVKNEQSEYNGKTYDNLNIKKMEQSELPPYSGAVSSEPAPAKADDLDLPF
                     "
     gene            3857..4654
                     /locus_tag="VQ862_001973"
     CDS             3857..4654
                     /locus_tag="VQ862_001973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014411877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional DNA primase/polymerase"
                     /protein_id="HET3116261.1"
                     /translation="MVGMVDYALHYQKLGYSVIPIDKKSKRAITKFKDKTFSENEIRR
                     FWHEQPDANIAWRTTDFFVIDIDVSVTENGYESLKEWELSQYIPKTLTATTPSGGKHI
                     FLKKPKGIELSQDIRVKPGIDIKANKNNYVLVAPSNNAKGSYKWDKSTEQMAEAPAEI
                     ISILQTSKQPKELMNFTTDYSRGEFSSKTAKLFEQVVFGLGDKGGRNNALASFIGGLL
                     MRGVDVDATYLLAKIANHYTPDSLPADEVDRTFESMVRKEMDRRGGY"
     gene            4590..6194
                     /locus_tag="VQ862_001974"
     CDS             4590..6194
                     /locus_tag="VQ862_001974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012972454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase family protein"
                     /protein_id="HET3116262.1"
                     /translation="MKWIERLKVWLERRWIEEVAIDLQKLKEEYRNNIIQHPAYIEKA
                     NDWREIRLACREYRKNWLENVKWEETQYGTKEENKKAPTRLTELAVAKGMEQILYIVN
                     LPNERVAIYDPDKGYYHKDPSFAYKVIRLLEPNFSEAKSKNVLFMLASTPRLNQHEGF
                     SCDFSIGEYKDPRRFILVKNGIYDKKEKLLRPFTHEFVAFSTIGTEYDHFAKSHEIDG
                     WDIDSWLLDLMSGDEELVQLIWQVISASLNGNYSYRKSIWFVGEGNDGKGTVQQLITN
                     LVGMRNVASLKLNQFSERFALSMIEGKTVIIGDDVQAGIYVDESSNFNSVVTGEPILV
                     EEKNKQPYTTVFKKTVIQSTNELPRFKNKTNGTYRRFAIIPFKKSFSSKEDNWAIKDD
                     YIYREEVLEYVLKKALEISFDRFIEPQASIEALENFKESNDTVKAFVSEWFDKFESTR
                     LPSRFLWWLYQEWCKDEGVTRLTKRKFETQLAKNIPENWVKKKIKPLGKFIPSVDVPK
                     HYSGFSWLNDESQILTSGYELVTVYR"
     gene            6446..6754
                     /locus_tag="VQ862_001975"
     CDS             6446..6754
                     /locus_tag="VQ862_001975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000834374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VRR-NUC domain-containing protein"
                     /protein_id="HET3116263.1"
                     /translation="MKSEQEVQNEIRVALSQAGYTVFRTNVGKVKTADGRWFDTGLPK
                     GHADLYGFRPDGQIFYVEVKKENGRVRPEQENFIETVRKRGAIAGVARSAKEALELVK
                     "
BASE COUNT         2338 a         1151 c         1575 g         1789 t
ORIGIN      
        1 cgaggctata accatgctta cgaacgtggt agagaggcac agcgccaaga aatccgcaag
       61 aatatccgtc gggagttcaa gggctttacg tttgataacg aaccgcctgt aggtttacgt
      121 ccagaacctt tagcattacc agagccaagg agagcacgat atgcaaatcg tatgggatag
      181 acaagcgtgg gatttattca cttgcaaacg tagagagaag atgcgtgacc ttgaaatgat
      241 ggcgcatatg caacatgaaa tcgatgatct caagaaacaa ttgcaacagg aacaatcttt
      301 aagaaagaga ttagaagcag agaatttcca actgaaacta aggaggaaat gatgtactta
      361 tggaagtgta cgtgcgctga ttgtgtacgt gagtttgatt ggtacgataa ctatccacct
      421 cttgaatgtg tgaaatgtga gagcgtggaa atcaaaaatg aatttaaagg aagggcgtat
      481 gattaaatga ctcaagcgga acgaattagg aaatattaca aagaccaccc tactgcctca
      541 tatgatgaag tggctgaggt tgtcggaact tcaaatagta atgtgagggt taatcttttt
      601 aaagacctca aggcaggcag atgtgtccgc ttagaagatg agtcaattga ctactcacct
      661 tattttaatc acaaaaaatc actgacagag ttgtttgatt ggaagaatga cactagacgg
      721 gaatgggtag atatgctgac aagagcagca gagaaagaaa cggatagtaa cgttatgcgt
      781 ctgctgatca aggaagcaaa taaattgatg aaagaggtga cgaaatgacg aagagtttat
      841 atgcaatagt aggtcaattt cttgaaatct ataacatgga attagacgaa gaaaccaaac
      901 tagacacctt ggattccatt gattgggaaa ctgattatga gactaaggtt gaaaattgta
      961 tcaaagttgt gaaaaatatc gatgcagata tggaagcccg tgacgcagaa atcaaacgct
     1021 tgacgaattt aaacaagttc gacaagaaga aaaaagaata cttgaaagaa cgagtttctg
     1081 aaagtatgaa attgacaggt catgaacgtg ttgatacacc actttttaag gtatcattta
     1141 gaaaatctca agcagttgaa gtgaatgagg cggtcttgcc agaggtctac aaggtagcca
     1201 cttggaagcc tgacaagaaa cttctgaaag aggatttgaa gaatggcctt gaaatcatcg
     1261 gtgccagcct agttgaaaga aagaatttga gtataaggtg aaaataacaa aagcaacaga
     1321 aattacgaat gatgatgcct gttacctgat ttatggaaat ccaggctttg ggaaaacgac
     1381 tactatctca ttcataccag ggaagacact aataatcaat atcgataaat cagccaaagt
     1441 attagctggc aatccgaaca tcgatatcgc agatgttgat acacataaga tttgggatga
     1501 atggttgact gtcgttaagg aattgcttca aggtgcaggg aagccatacg atactatcgt
     1561 tgtggataac gtatctgaat tattcagagc gtgtcttgct aatcttggtc gagatggaaa
     1621 aaatcatcgg gttccaactc aggcagatta ccaacgagtc gattttacga ttttggatag
     1681 tctacgagcc ttattgcaat taaataaacg gattgtattc acggcttggg aaacatctga
     1741 tcagtggtca gatgaaaatg gcatgattta caacagggcc atgccagata ttcgttccaa
     1801 aatcttaaat aatttccttg gtttaacaga tgtagtcgct cgtctagtca agaaaacgac
     1861 agacgacggt gaggaagtga gaggttttat cttacaacct agtgccagcg tctatgccaa
     1921 gaatcgtttg gacgatagaa aggggtgtaa agtagatgag cttttcgctc agagattacc
     1981 agaaggaact gataattgac gttatcaaat ccatgaaggc aggcaatcga aagataatgg
     2041 ttcaatcccc cccacgttca ggtaaaacgg tcgtgatgtc ttacatcgct aagaatgcaa
     2101 cggataaaga taagacggta ttgtttttca gtcaccggaa agaaatcaat gagcaggttc
     2161 atgaggcttt caaacgtggc ggagttaatc ttgataaggt tattatcgga acggttggga
     2221 gtattgtgcg aaagttagaa cgattgcctc aagtcgatgt aatcttagta gatgaagctc
     2281 atcatatcaa agcaaaacaa tatcagacaa tcttaaatta tttcagtaat gctactcaat
     2341 tgtttttcac aggtacgcct atccgattgg atggttcagg attccacgat ttagcagatg
     2401 atttagtagt tggtaaatcc atcctatggc ttcaagacca cgggaatatc gctgaatttg
     2461 attactattc catcaatctg ttggatatgg ccaaacttaa aaaacgatca ggagaattta
     2521 ccaaccattc aatcgatgta gcatttgatt ccaaggcgac gtatggtgat tatatcgatc
     2581 actacgagcg attagccaaa gggaaacaag ctatcgttta tacacatagc gtagaatacg
     2641 ctgagagggt cgctaagcga tttttagagc aaggctacca atctgctgtc gtgtccggaa
     2701 aaacgccaca gggcgaacga gagagccata tgcaggcatt tagggaagga aaactcacaa
     2761 tcatggtcaa tgtcaatctt tttacagaag gaattgactt gccaaatgta gatgtctgta
     2821 ttatgttacg accgactgac tcgctttccc tgtatcttca attcgctatg agggccttaa
     2881 atccaagaga aggcaaaaaa gcaatcttga tagaccacgt tggaaatcat atccggcatg
     2941 gtctaccgaa tgacgatagg gaatggacgc tggacgggac taagaagaaa aagaaatctt
     3001 cagaacgttc aacggtgacg tgtgagaaat gttttgcgac attttggaga gagcagctag
     3061 tagatggttg ttgtccgtac tgcaaggcgg agattgtcga gaagaaaaac attcaagata
     3121 tcaaacaaga taaatcagat attcaattaa caaaaatcaa tcaaggaatg gaatttatta
     3181 ccattcgagg caaagaaata gaggtcaaga cagaagaagc gaaagtgtat cgtcgcgtca
     3241 agacctatgg taaacgatac acaagatgtc agaacttgtc ggaattaaaa gcattccgat
     3301 tgcttaatgg ctatcaacca ggttggttat ggcacaaaca aaaagaatta aatttatgga
     3361 gataataaac atggcacttt tttcagtaaa ttatgaagca gcagaacaat tttcatctat
     3421 cgaagacgga acatatgaag tagttgtagc tcaagcagaa cagtcagcaa gtcaaagtgg
     3481 aacagatttc ttagatattc gcttgaaaat tcgtgatgat ttccaacaga aattccgtaa
     3541 caatctaatt tttgataagg tgtggatcaa taaacagact cttcaatatc cagaatgggc
     3601 attgcaacgc tattctaaag cagttaaaat tccagaggga gttgaagtga atacaatcga
     3661 gcaattctta ggacttatca ttggtaaaac actgaaagtt actgtaaaaa atgagcagtc
     3721 agaatacaat ggtaagacct acgataactt gaatatcaag aaaatggaac aatctgagtt
     3781 gcctccgtat tctggagcag tatcgtctga accagctcca gctaaagcgg atgatttaga
     3841 tttaccattc taatctatgg ttgggatggt agattatgcc cttcattatc aaaaactagg
     3901 ttactcggtc atcccaatag acaaaaagag caaacgtgca atcacgaaat tcaaggataa
     3961 aacatttagc gagaatgaaa ttaggagatt ttggcacgag caacccgatg cgaacatcgc
     4021 atggaggaca accgatttct ttgtcatcga tattgatgta tcggtgactg agaacggtta
     4081 tgagtcttta aaagaatggg aattgtctca gtatattcct aagactttaa ccgctactac
     4141 gccgagtgga ggaaagcaca tttttcttaa aaaaccaaaa ggcatagagt taagtcaaga
     4201 tatacgagta aaaccaggaa ttgatattaa ggcgaataaa aacaattatg tcttggttgc
     4261 acctagcaat aatgccaaag gaagttataa gtgggataag tccacggaac agatggcgga
     4321 agcaccagct gagatcatct caatcttaca aacatctaaa caacccaaag aacttatgaa
     4381 ttttacaact gattacagtc gaggggagtt ttcaagtaag actgccaagc tattcgaaca
     4441 agtcgttttc ggtttaggcg ataaaggtgg tagaaataac gccttggcga gttttatagg
     4501 cggcttactc atgcgtggtg tggatgtgga tgcaacctat ttactagcaa agatagcaaa
     4561 tcactatact ccagacagtc tgccagctga tgaagtggat agaacgtttg aaagtatggt
     4621 tagaaaggag atggatagaa gaggtggcta ttgatttaca gaaattaaaa gaagaatatc
     4681 gaaacaatat tatccaacat ccagcttata tcgagaaagc aaatgactgg cgtgagattc
     4741 gtttggcttg tcgtgaatat cggaaaaact ggctcgaaaa cgttaagtgg gaagaaaccc
     4801 agtacggtac gaaagaagaa aataaaaaag cgcctactcg tttaacggag cttgcagtcg
     4861 caaagggtat ggaacagatt ttatatatcg tgaatctgcc aaatgaacgg gtcgcaatct
     4921 atgatccaga taaaggctat tatcacaagg accctagttt cgcttataaa gtcattcgct
     4981 tactagaacc aaatttcagt gaagcgaaat ccaagaatgt tctcttcatg cttgcttcta
     5041 caccacggtt gaaccaacac gaggggttct catgtgattt ctcaattggg gaatacaaag
     5101 acccccgtag gtttatctta gtgaagaacg ggatatacga caagaaagaa aaattactac
     5161 gaccattcac acatgagttt gtcgcattct caaccatcgg gacggaatac gaccactttg
     5221 ctaagtccca tgaaatagac ggatgggata ttgatagctg gttacttgac ctcatgagtg
     5281 gagatgaaga actagttcaa ctaatctggc aggttatctc agccagtctg aatgggaatt
     5341 actcctacag gaaatccatt tggttcgtcg gtgaggggaa tgacggtaag gggactgtcc
     5401 agcaactcat aaccaatctg gtcggtatgc gaaacgtggc cagtttaaaa ctcaatcagt
     5461 tttcagagag atttgcttta tcgatgattg aaggtaagac cgtcatcatc ggggacgatg
     5521 tgcaagctgg tatctacgta gatgaatctt caaatttcaa ctctgtcgtg actggtgagc
     5581 caatcttggt tgaggaaaaa aacaaacaac cgtatacgac cgtatttaaa aaaactgtca
     5641 ttcaatctac aaatgaatta ccacgtttta agaataaaac caatggtaca tatagacggt
     5701 ttgcaatcat accgtttaag aaatcattct caagcaagga agataactgg gcaatcaagg
     5761 acgattacat ctatcgtgaa gaagttcttg agtacgtttt aaagaaagcc cttgagattt
     5821 catttgatcg ttttattgaa cctcaagcat cgattgaggc cttggagaat ttcaaagagt
     5881 ccaatgatac agtcaaggcg ttcgtcagcg aatggttcga taaattcgaa tccactcgcc
     5941 ttccgtcccg atttttgtgg tggttgtatc aggaatggtg taaggacgaa ggtgtcacaa
     6001 gattgacaaa acgtaaattt gaaacgcagt tagctaagaa tatcccagag aactgggtta
     6061 agaaaaaaat caaaccgtta ggaaaattca ttccttcagt agatgtaccg aagcattatt
     6121 caggttttag ttggttgaat gatgaaagtc agatacttac atcggggtat gaattggtta
     6181 ccgtttaccg ttaggttacc gttctttttt tgactacggt aacctgattt aagccttatg
     6241 tatcaagggt ttacctcttg taggttaccg tattaccttt cttttctatt gaattaataa
     6301 aaaaataaat aatataaata taaataaagg ggaaaggtaa cggtaacggt aaccttgggg
     6361 caaaaaaatg acgtaaaccg ttggtactac tggatttgta gtggttaccg ttctaaaatc
     6421 aataacggta acttttggag ggaaaatgaa gtcagagcaa gaagtacaaa atgaaattag
     6481 agtcgcattg tctcaagctg gatataccgt atttcgaacg aatgttggaa aagttaagac
     6541 cgcagacggc agatggtttg atactggatt gccgaaaggt catgcagatc tgtatggttt
     6601 cagaccagac gggcagatat tttatgttga agtaaaaaaa gaaaatggtc gtgtgagacc
     6661 tgaacaggaa aattttattg agacggttag aaaacgaggt gcgatagctg gtgtagctag
     6721 aagcgccaag gaagcgttgg agttagttaa atgaataatc aattaaaggt agaagtacaa
     6781 tgtccgtttt gtggggagtg tatcacgaga tattgcagag gatagtggat gggatttgat
     6841 aggaggtagg aaa
//
LOCUS       DAVBOD010000081         6806 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 640-05
            SAMEA1012484-rid20186543.denovo.082, whole genome shotgun sequence.
ACCESSION   DAVBOD010000081 DAVBOD010000000
VERSION     DAVBOD010000081.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012484
            Sequence Read Archive: ERR059358
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6806)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6806)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979948.1
            Genome Coverage       :: 595x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:03:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,266
            CDSs (total)                      :: 2,219
            Genes (coding)                    :: 2,091
            CDSs (with protein)               :: 2,091
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 71 of 128
            Pseudo Genes (incomplete)         :: 50 of 128
            Pseudo Genes (internal stop)      :: 33 of 128
            Pseudo Genes (multiple problems)  :: 22 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6806
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012484-rid20186543.denovo.082"
                     /strain="NIG 640-05"
                     /db_xref="taxon:1313"
     gene            complement(<1..207)
                     /locus_tag="VQ862_001976"
     CDS             complement(<1..207)
                     /locus_tag="VQ862_001976"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3116264.1"
                     /translation="MENMTNHLLLVQIRVHGYLLDFASSEGQRQKHYRLKNLPQTVEL
                     TVDDVEEDVDLTLPENRSYQEADFF"
     gene            complement(275..916)
                     /locus_tag="VQ862_001977"
     CDS             complement(275..916)
                     /locus_tag="VQ862_001977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3116265.1"
                     /translation="MIDIQGLEKKFNDRAIFSGLNLKLEKGKVYALIGKSGSGKTTLL
                     NILGKLEKIDGGRVLYQGKDLKTIPTREYFRDQMGYLFQNFGLLENQSIKENLDLGFV
                     GQKISKVERLERQVGALEKVNLGYLDLEQKIYTLSGGEAQRVALAKTILKNPPLILAD
                     EPTAALDPENSEEVMNLLVDLKDENRIIIIATHNPLVWNKADEIIDMRKLAHV"
     gene            complement(918..2947)
                     /locus_tag="VQ862_001978"
                     /pseudo
     CDS             complement(918..2947)
                     /locus_tag="VQ862_001978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000825281.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
     gene            complement(3216..4115)
                     /locus_tag="VQ862_001979"
     CDS             complement(3216..4115)
                     /locus_tag="VQ862_001979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000904853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET3116266.1"
                     /translation="MLIGQKIKEIRIEKGISRPDFCGDEQELTVRQLSRIESGASQPS
                     LPKLDYIARRLGVPVYSLMPDFSALPPAYLELKYQILREPIYGKEEEYDKKEACLEEI
                     YKTYFDNLPKEEQLACEVLQACLDTSRTRRPEYAELILEEHMPQIIEKEVYSTNDMLL
                     IRLFFYQMLIRKDLAKFINQIEKLMLFLLEQKKVTKLENFFIIRDTLISGMCCLEKVG
                     VTDCFNDYLSCLQEIMDKTQDYQKKPLVFMFLWKQALREERDFSLAESFYQSSKTFAQ
                     LIGDEFLVKKLTEEWQEDVKKYL"
     gene            complement(4187..4747)
                     /gene="rnmV"
                     /locus_tag="VQ862_001980"
     CDS             complement(4187..4747)
                     /gene="rnmV"
                     /locus_tag="VQ862_001980"
                     /EC_number="3.1.26.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000660004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease M5"
                     /protein_id="HET3116267.1"
                     /translation="MKEKISQVIVVEGRDDTVNLKRYFDVETYETRGSAINDQDIERI
                     QRLHQRHGVIVFTDPDFNGERIRRMIMTVIPTVQHAFLKRDEAVPKSKTKGRSLGIEH
                     ASYEDLKTALAQVTEQFEHESQFDISRSDLIRLGFLAGADSRKRREYLGETLRIGYSN
                     GKQLLKRLELFGVTLAEVEEAMKSYE"
     gene            complement(4747..5520)
                     /locus_tag="VQ862_001981"
     CDS             complement(4747..5520)
                     /locus_tag="VQ862_001981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000575597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HET3116268.1"
                     /translation="MIFDTHTHLNVEEFAGREAEEIALAAEMGVTQMNIVGFDKPTIE
                     HALELVDEYEQLYATIGWHPTEAGTYTEEVEAYLLDKLKHSKVVALGEIGLDYHWMTA
                     PKEVQEQVFRRQIQLSKNLDLPFVVHTRDALEDTYEIIKSEGVGPRGGIMHSFSGTLE
                     WAEKFVDLGMTISFSGVVTFKKATDLQEAAKELPLDKMLVETDAPYLAPVPKRGRENK
                     TAYTRYVVDFIADLRGMTTEELAAATTANAERIFGLDSK"
     gene            complement(5825..6718)
                     /locus_tag="VQ862_001982"
     CDS             complement(5825..6718)
                     /locus_tag="VQ862_001982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001816585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1542 domain-containing protein"
                     /protein_id="HET3116269.1"
                     /translation="MVAQDPKAQDSTKPTAEKSTVKAPAQRVDVKDITHLTDEEKVKV
                     AILQANGSALDGATINVAGDGTATITFPDGSVVTILGKDTVQQSAKGESVTQEATPEY
                     KLETTPGGDKGGNTGRSDANANAGGGSQAGGPVHTGSQNSAQSQASKQLATEKESAKN
                     AIEKAAKNKQDEIKGAPLSDKEKAELLARVEAEKQAALKEIENAKTMEDVKEAETIGV
                     QAIAMVAVPKRPVAPNAAPKTTSAPQATAGTMQDVTYQSPAGKQLPNTGSASSAALAS
                     LGLVVATSGFALLGRKTRRRK"
BASE COUNT         1906 a         1621 c         1175 g         2104 t
ORIGIN      
        1 aaaaaaatca gcttcttgat aacttcgatt ttcgggtagg gtcaaatcca catcctcctc
       61 cacatcatcc actgtcagtt caaccgtttg aggtaaattt ttcaaacgat aatgcttttg
      121 cctttgccct tcactactag caaaatcaag caaatagcca tgcactcgga tttgaaccaa
      181 aaggagatga ttggtcatat tttccatgat gaggatatct tataaaccac ctctggcact
      241 aggataatca gataccctgc gaatacggat tttttcacac atgagcaagt ttcctcatat
      301 caatgatttc atcagcctta ttccagacta ggggattatg ggtcgcaatg atgataattc
      361 gattttcatc tttcaaatcc accaagagat tcataacctc ctctgaattt tcaggatcaa
      421 gagctgctgt tggttcatct gccaaaatca agggtggatt tttcaaaata gttttcgcaa
      481 gggcaactcg ttgggcctct cccccagata aagtataaat tttttgttct aaatccaaat
      541 accctagatt aactttttct aaagccccca cttgcctttc caaacgttct acttttgaga
      601 ttttctgacc aacaaaaccc aaatccaaat tttctttgat tgattggttt tctaagaggc
      661 caaaattttg aaagagatag cccatctgat ctcgaaaata ctcacgagtg ggaatggttt
      721 ttaaatcttt cccctgatag agaacccttc ctccatctat cttttctagc tttcccaaga
      781 tattcagcag cgtcgtcttt ccgcttccac tctttccgat taaggcataa accttgccct
      841 tctccagctt gagattcaaa ccagagaaaa tcgcgcggtc attaaatttc ttttccaatc
      901 cttgaatatc aatcatctta ttttcctttc aatactgcca tgctaccagc ttcttctttt
      961 ttgtcctgcc ttactaaaat caagagggcg ttaagcgtaa acaaagctac aactagagcg
     1021 ctaatcaaac catctcttgt caaaatacta gataggacta ggccaagcaa gagaactcct
     1081 ccttgcgcca gtaaatactt gccatgaagc tcatagattg tcataccagc aagacgttta
     1141 atcataagct cccgtctgaa ctgctcaaaa tagagaagat tcatggaatc aaataacaag
     1201 atagccgtag acagggtcaa aatcgtccca ataaggagag agtaaaactc tacccgtttg
     1261 tcatttagta ccttggcaaa aatagctggc tttttaccaa gtaagaaacc ttgtgataca
     1321 gaccttgctc ttttagagct gtgatgctgt ctccatatcg atctagtttc aaggcactat
     1381 tagccgtagt tccccacaac atccctgcaa caggtcttgt tccagtcgct tgcggcgtta
     1441 gaactacaat aatcggatct tttaggtact ggcgtgttgt cttgtaccca tcattataga
     1501 ggaaacgttc ctgtcctgtt tctgtaaaag ctagacttac ctgtgggagg tagtatttct
     1561 gactcgtcac ttctacactt tcagatgaaa agttttgcag gtaatctgta aacaatcctt
     1621 ggtagtaggc agactgctct cgcaagctct caggcaagat cagcccaaac tctccctcag
     1681 acaagttttg catcttgtcc ataaactctg aagaaacggt aatcttttct tctatcagat
     1741 agcgtggtga gacatagata acattccctg acggtgtgta gtcactgaga cgattgccat
     1801 ctaggtccac ttctgctccg tctgagaaat tgtcaacatt gctcataata taaaaagagt
     1861 ctgtattggc taaccgttct tcagtaaatg tctgccactc acgattatcc ttacgcgttc
     1921 cttcttcatc ggcaaatgca ctagaccaac caaaggatag acggtaacgg tctgaggact
     1981 ggctccattt attgctagct ctctccattt cctgcatttc acggtagtgg ggtaggagag
     2041 ctgtcgcact cgatccgacc accaatacag ctaagagttg ccccaccatc atcaatgtca
     2101 tcatacgttt gagagggagt ttccctttca atagatccac cagactattt tcctgtaaac
     2161 caagtagata gacgacactt agtaaggtag aaatccctgc cagggtcaat ccataaagta
     2221 gaagagcaat gatgaccagt tgcaccgttg ccataaacaa gacaccttga taccagagaa
     2281 tccccaatcc caaaagactg gataccagca ctgagtagat aaactgtctc acatcttcta
     2341 acactggtct gagagcaact ccaaacaagc tctcaccagc tattaagcga atccctgcct
     2401 gacgaaggga tttgatccga taaatcaggg tcagactcat aaaggtcagc agaaaaatag
     2461 ctaaactcag tagcaccata ggggtggccg ccaatagtaa gactatcgaa aatggatctt
     2521 ctccattcga aacaaagcct tgatagccaa gttctttcaa ggtggtctgt aagctcactc
     2581 catccaaact tcctgacaca atcaagtaag accctaataa atcactcgtt tctgcactct
     2641 ccttggagga aatggtcaga ccttctggaa gctctccctc accataagtg gcataggtaa
     2701 agagtgtttc tccagcttca tttggctcaa cgattcgacg ggcgatgaga ctattatgct
     2761 ctaccgccaa gtgactcaaa acctctgtca cctcttcgcg actagctact ggttgattta
     2821 tcatcattcc tgtcacatca acagaaggat agttaccaaa taaaatctct tctcgatggt
     2881 caacggaagt tatcaccata taaagcgata ccaataccat tgaaatcaaa ataaataaac
     2941 gtttcatcat ttcctccaaa aagttacttg gtcacttagt gagaaggtga ccacagtcac
     3001 tgcgatgtta agaagcttat taagttcttt ctactagcaa catcttcaaa tacattatat
     3061 ccgttttttc aagaactatc aaggacatca atgtccttaa aatctaacca tttcgtgtca
     3121 tttttagctt atatctaaaa aaacagccct aaagacgaac tttagaactg ttttgatgcg
     3181 agaacaagga catttttgtc actgattcac tatgtttata aatatttttt gacatcctct
     3241 tgccattcct ctgtcaattt ctttactaga aattcatctc caattagctg cgcaaatgtt
     3301 ttagaagact gataaaatga ttcagctaaa ctaaaatctc tttcttctct taatgcttgc
     3361 ttccacaaaa acataaatac aagaggtttc ttttgataat cttgagtttt atccataatt
     3421 tcttgtaaac acgatagata atcattaaaa caatcagtta ctcctacctt ttcaagacaa
     3481 cacattcctg aaataagagt atctctaatt ataaagaagt tttctaattt agttaccttt
     3541 ttctgttcca aaagaaagag cattagcttt tcgatttgat ttataaattt ggcaagatct
     3601 tttctaatga gcatttgata aaaaaacaaa cgaatcaaca acatatcatt tgttgaataa
     3661 acttcttttt ctatgatctg aggcatatgt tcctcaagta ttaactctgc atattcaggc
     3721 cttctagttc tagaagtatc caaacacgcc tgcaatactt cacatgctaa ttgttcttct
     3781 ttaggaagat tatcaaagta tgttttataa atctcttcca aacacgcttc cttcttatcg
     3841 tactcctctt ctttaccata gattggttca cgtaaaatct ggtatttcaa ttctaaataa
     3901 gcaggaggaa gagctgaaaa atccggcata aggctataaa ctggaactcc tagccggcga
     3961 gcaatatagt ctaacttggg caaactcggt tgcgaagctc cactttcaat tcgcgacagt
     4021 tgacgaactg tcagttcttg ctcatctcca caaaaatctg gacgactaat tcctttttct
     4081 atccgaatct ctttaatttt ttgaccaatt aacatcagac gcctcctctt ctacctgctt
     4141 cgaaaaatac tgtgaaactt aaaaaattgt aacggctaca tctttcctac tcataagatt
     4201 tcatagcttc ttccacttct gccaaagtaa ccccaaacaa ctctaggcgt ttgaggagtt
     4261 gcttgccgtt ggaatagccg attcggagag tctctccgag atattctcta cgcttacggc
     4321 tgtctgcccc tgctagaaaa ccaaggcgaa tcaaatcgct acgactaatg tcaaactgac
     4381 tctcatgttc aaattgttct gtcacctgag ctagagccgt tttcaggtct tcatagctgg
     4441 catgctcaat tcccagagaa cgccccttgg tcttggactt gggaacagct tcatctcgct
     4501 tgagaaaggc atgctgaact gttggaatga ccgtcatgat catgcgccga atccgttccc
     4561 cattaaaatc tgggtctgta aagacaatga ctccatgacg ttggtgcagg cgctgaatcc
     4621 gctctatatc ctgatcattg atggcagaac ctcgagtctc ataggtctcc acatcgaaat
     4681 aacgcttgag attgaccgta tcatcacgcc cttcaaccac aattacttgg gaaattttct
     4741 ctttcattac ttgctgtcca atccaaaaat gcgttctgca tttgcagtcg ttgccgccgc
     4801 tagctcttct gtcgtcatac cacgcaagtc agcgataaag tcgaccacat agcgagtata
     4861 ggctgtttta ttttcacggc cacgcttggg tacaggtgct aagtaaggcg catctgtttc
     4921 caccaacatc ttgtccaaag gtaactcttt agctgcttct tggaggtcag ttgccttctt
     4981 gaaagtcacc actcctgaga aggaaatggt cataccaaga tccacaaact tctctgccca
     5041 ctcaagcgtc cctgaaaatg aatgcatgat accaccacga ggaccaacgc cctcactctt
     5101 gataatctca taggtatctt ccagcgcatc acgggtatgg acaacaaaag gcaaatccaa
     5161 gttcttagat agctgaatct gacggcgaaa aacctgctcc tgcacctctt tgggcgctgt
     5221 catccaatgg tagtctaagc caatttcacc taaagccaca accttggaat gttttaactt
     5281 atccaacaag taagcctcaa cttcctctgt ataagtacca gcttctgtag gatgccaacc
     5341 aatagtcgca tagagctgct catactcatc taccaactcc aaggcatgct caatcgtcgg
     5401 tttatcaaaa ccaacaatat tcatctgtgt cacacccatc tcagcagcca aggcaatttc
     5461 ttctgcctca cgacctgcaa attcttctac attcaagtgt gtatgtgtat caaaaatcat
     5521 ctcttctaac ctcgttttct atcttctatt ataccaaaaa agaggagggg cacctaattt
     5581 ttcggtttcc cctcctctct tcaataaaga gctattctgc tatcttttct atccgatatt
     5641 gcccatctcc tattccacag ttagagacag aagagattgg ctacattgat agaatattcc
     5701 tattcagcta aagtatgtga ttatcttggg ttctcacttt tctcacccat cactaggatt
     5761 gatgacttct caaaatcccc cttataatct aactttaagt agagaataga attttctagc
     5821 tgttctattt tctacgtcta gtctttcttc ctagcaaagc aaaaccactt gttgccacca
     5881 ctagaccaag actagcaagt gctgcacttg atgctgaacc tgtgttaggt aattgtttgc
     5941 cagcaggtga ctggtaggta acatcttgca ttgttcctgc agttgcttgc ggtgcacttg
     6001 ttgtcttagg agcagcatta ggagccactg gtctcttagg aactgcaacc atggcaatgg
     6061 cttgcactcc aatcgtttct gcttccttca catcttccat agttttcgca ttttcaatct
     6121 ctttgagagc tgcttgtttt tctgcttcca ctcttgctaa aagttctgct ttttctttat
     6181 cagaaagcgg tgcgcctttg atttcatcct gcttgttctt ggctgctttt tcaatggcat
     6241 ttttagctga ttctttttca gtagctaatt gcttagaagc ttgtgattga gctgagtttt
     6301 gtgaacctgt gtgaactggt ccacctgcct ggctaccacc gcctgcattc gcattagcat
     6361 ctgatcttcc agtattgcct cccttatctc cacctggtgt agtttctagc ttatactctg
     6421 gtgtagcttc ttgagttaca gattcacctt tcgcagattg ttgaactgta tcttttccta
     6481 gaatcgtcac tactgaacca tctgggaatg tgattgttgc tgtaccatct ccagctacat
     6541 tgattgtcgc tccgtctaat gctgaaccat ttgcttgtaa aatagcaacc ttaacttttt
     6601 cttcatctgt taaatgagtt atatctttta catctactct ttgagcaggt gctttaacag
     6661 ttgatttttc agcagtcggt ttagtactat cttgtgcttt tggatcttgt gctaccaatt
     6721 gatttcctgg aattgtaata gctgaaccat ctttaaagac gattgtcgct gtaccatctc
     6781 cagctacttc aactttatag taaaat
//
LOCUS       DAVBOD010000082         6792 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 640-05
            SAMEA1012484-rid20186543.denovo.083, whole genome shotgun sequence.
ACCESSION   DAVBOD010000082 DAVBOD010000000
VERSION     DAVBOD010000082.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012484
            Sequence Read Archive: ERR059358
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6792)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6792)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979948.1
            Genome Coverage       :: 595x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:03:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,266
            CDSs (total)                      :: 2,219
            Genes (coding)                    :: 2,091
            CDSs (with protein)               :: 2,091
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 71 of 128
            Pseudo Genes (incomplete)         :: 50 of 128
            Pseudo Genes (internal stop)      :: 33 of 128
            Pseudo Genes (multiple problems)  :: 22 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6792
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012484-rid20186543.denovo.083"
                     /strain="NIG 640-05"
                     /db_xref="taxon:1313"
     gene            <1..379
                     /locus_tag="VQ862_001983"
     CDS             <1..379
                     /locus_tag="VQ862_001983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS630-like element IS630-Spn1 family
                     transposase"
                     /protein_id="HET3116270.1"
                     /translation="RGKVSGRRYQRISLVAGLTNGELIAPMTYEETMTSDFFEAWFQN
                     FLLPTLTTPSVIIMDNVRFHRMGKLELLCEEFGHKLLPLPPYSPEYNPIEKTWAHIKK
                     HLKKVLPSCNTFYEAFLSCSCFN"
     gene            440..1402
                     /locus_tag="VQ862_001984"
     CDS             440..1402
                     /locus_tag="VQ862_001984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HET3116271.1"
                     /translation="MNMSNITIDGQEIDLSQTMPSYAQVVSLYDDTSISVSSNETDKV
                     LAGSLYTDTNEQGLTIPSSLLKNWNEQTGKNLTANDLIGKSVSASIVESAAETSKIAQ
                     FQTKIVRVINDEDDMEDSNSFMLSHQMETILKEAGFTKAVSYFILELKDPSQTKVVTE
                     ELQKNKKYTVLSQQRVLDIVITFIRVIQGLLIVLSSQAIVVAAVMIGIIIYINIMQRS
                     KEIGVMKAVGYQNRDVKGIFIYEAIWIVGIALLLAFLVAQGVGSLANAIVSHFYPSIT
                     KVFELNLLSVLGTLVFALLLGYVSAYFPARKISKMDPVEPLRYE"
     gene            1579..2586
                     /gene="gap"
                     /locus_tag="VQ862_001985"
     CDS             1579..2586
                     /gene="gap"
                     /locus_tag="VQ862_001985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008090210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HET3116272.1"
                     /translation="MVVKVGINGFGRIGRLAFRRIQNVEGVEVTRINDLTDPVMLAHL
                     LKYDTTQGRFDGTVEVKEGGFEVNGKFVKVSAERDPEQIDWATDGVEIVLEATGFFAK
                     KEAAEKHLKGGAKKVVITAPGGNDVKTVVFNTNHDVLDGTETVISGASCTTNCLAPMA
                     KALQDNFGVVEGLMTTIHAYTGDQMILDGPHRGGDLRRARAGAANIVPNSTGAAKAIG
                     LVIPELNGKLDGSAQRVPTPTGSVTELVAVLEKNVTVDEVNAAMKAASNESYGYTEDP
                     IVSSDIVGMSYGSLFDATQTKVLDVDGKQLVKVVSWYDNEMSYTAQLVRTLEYFAKIA
                     K"
     gene            complement(2653..3489)
                     /locus_tag="VQ862_001986"
     CDS             complement(2653..3489)
                     /locus_tag="VQ862_001986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000216776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HET3116273.1"
                     /translation="MTVKQLLEEQLLIPRKIRHFLRIKKHILINQEEVHWNEIVNPGD
                     VCQLTFDEEDYPQKTIPWGNPDLVQEVYQDQHLIIVNKPEGMKTHGNQPNEIALLNHV
                     STYVGQTCYVVHRLDMETSGLVLFAKNPFILPILNRLLEKKEISREYWALVDGNINRK
                     ELVFRDKIGRDRHDRRKRIVDAKNGQYAETHVSRLKQFSNKTSLAHCKLKTGRTHQIR
                     VHLLHHNLPILGDPLYNSKSKTSRLMLHAFRLSFTHPLTLERLTFTTLSNTFEKELKK
                     NG"
     gene            3615..5810
                     /locus_tag="VQ862_001987"
     CDS             3615..5810
                     /locus_tag="VQ862_001987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HET3116274.1"
                     /translation="MKLDKLFEKFLSLFKKETSELEDSDSTILRRSRSDRKKLAQVGP
                     IRKFWRRYHLTKIILILGLSAGLLVGIYLFAVAKSTNVNDLQNALKTRTLIFDREEKE
                     AGALSGQKGTYVDLTDISKNLQNAVIATEDRSFYKNDGINYGRFFLAIVTAGRSGGGS
                     TITQQLAKNAYLSQDQTVERKAKEFFLALELSKKYSKEQILTMYLNNAYFGNGVWGVE
                     DASKKYFGVSASEVSLDQAATLAGMLKGPELYNPLNSVEDSTNRRDTVLQNMVAAGYI
                     DKNQETEAAEVDMTSQLHDKYEGKISDYRYPSYFDAVVNEAVSKYNLTEEEIVNNGYR
                     IYTELDQNYQANMQIVYENTSLFPRAEDGTFAQSGSVALEPKTGGVRGVVGQVADNDK
                     TGFRNFNYATQSKRSPGSTIKPLVVYTPAVEAGWALNKQLDNHTMQYDSYKVDNYAGI
                     KTSREVPMYQALAESLNLPAVATVNDLGVDKAFEAGEKFGLNMEKVDRVLGVALGSGV
                     ETNPLQMAQAYAAFANEGLMPEAHFISRIENASGQVIANHKNSQKRVIDKSVADKMTS
                     MMLGTFTNGTGISSSPADYVMAGKTGTTEAVFNPEYTSDQWVIGYTPDVVISHWLGFP
                     TTDENHYLAGSTSNGAAHVFRNIANTILPYTPGSTFTVENAYKQNGIAPANTKRQVQT
                     NDNSQTDDNLSDIRGRAQSLVDEASRAISDAKIKEKAQTIWDSIVNLFR"
     gene            5863..6015
                     /gene="rpmG"
                     /locus_tag="VQ862_001988"
     CDS             5863..6015
                     /gene="rpmG"
                     /locus_tag="VQ862_001988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015912025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HET3116275.1"
                     /translation="MALKKASLACAVCGSRNYSIKISGNPKPTRLEVNKFCKHCGKYT
                     THRETR"
     gene            6025..6201
                     /gene="secE"
                     /locus_tag="VQ862_001989"
     CDS             6025..6201
                     /gene="secE"
                     /locus_tag="VQ862_001989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001211016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecE"
                     /protein_id="HET3116276.1"
                     /translation="MRFIGDIFRLLKDTTWPTRKESWRDFRSIMEYTAFFVVIIYIFD
                     QLIVSGLIRFINIF"
     gene            6256..6792
                     /gene="nusG"
                     /locus_tag="VQ862_001990"
     CDS             6256..6792
                     /gene="nusG"
                     /locus_tag="VQ862_001990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000376740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusG"
                     /protein_id="HET3116277.1"
                     /translation="MDSFDKGWFVLQTYSGYENKVKENLLQRAQTYNMLDNILRVEIP
                     TQTVQVEKNGKRKEVEENRFPGYVLVEMVMTDEAWFVVRNTPNVTGFVGSHGNRSKPT
                     PLLEQEIRDILVSMGQTVQEFDFDVEIGQTVRIIDGAFADYTGKITEIDNNKVKMIIS
                     MFGNDTVAEVNLNQIAEL"
BASE COUNT         2114 a         1190 c         1465 g         2023 t
ORIGIN      
        1 aagaggcaaa gtatctggaa gaagatatca gaggatttct ttggttgcag gtctaacaaa
       61 tggtgaatta atcgctccaa tgacttacga agagacgatg acgagcgact tttttgaagc
      121 ttggtttcag aattttctct taccaacatt aaccacacca tcggttatta ttatggataa
      181 tgtaagattc catagaatgg ggaagctaga acttttatgc gaagagtttg ggcataaact
      241 gttacctctt cctccctact cacctgagta caatcctatt gagaaaacat gggctcatat
      301 caaaaagcac ctcaaaaagg tattaccaag ttgcaatacc ttttacgagg cttttttatc
      361 ctgctcttgt ttcaattgac tatatatcac ggatacagtt gggaaagaag ctattaaata
      421 tttggagagt ccttttggga tgaacatgtc aaatattact atagatgggc aagaaataga
      481 tctgagtcaa acgatgcctt cttatgctca agtagtgagt ctttatgatg atacaagtat
      541 ctctgttagt agtaatgaga cggacaaagt gttggctgga tccctctata ctgatacaaa
      601 tgaacaggga ttaacgattc caagcagttt actaaaaaat tggaatgaac agacaggaaa
      661 aaatttgaca gctaatgatc ttattggcaa atcagtctca gccagcattg tagaaagtgc
      721 tgccgaaact agtaagattg ctcaatttca aacgaagatt gtacgtgtaa tcaatgatga
      781 agatgacatg gaggacagca acagtttcat gctgtctcat caaatggaaa cgattttgaa
      841 agaggctgga tttacgaaag ctgtatctta ttttatcttg gaactcaaag atccatcaca
      901 gacaaaagta gtaacagaag aattacagaa aaataagaag tatactgtgc tttctcaaca
      961 gagagttctt gatattgtga ttacctttat tcgtgttatt cagggattat tgattgtgct
     1021 ttcatcacaa gctattgtgg tagcagcggt tatgattggt atcattattt acatcaatat
     1081 catgcaacgt tctaaggaaa taggtgtcat gaaggcagtt ggttatcaga atcgtgatgt
     1141 caaaggaatt tttatttacg aggctatctg gattgtaggc atcgccttgc tgctggcatt
     1201 tttggttgca caaggggtgg gaagtttggc gaatgcgatt gtaagtcact tttacccatc
     1261 catcactaag gtttttgaat taaatctttt atctgtttta ggaactctag ttttcgctct
     1321 attacttggt tatgtctcag cctacttccc ggcgcgtaag attagtaaaa tggatcctgt
     1381 agaaccgtta cgctatgaat agtaagggat tccttgattt acagtcttaa aaagaaacta
     1441 acatagaaaa acaatggcca tacttgcaat tcaactcaaa tagttgtata ataggtttgt
     1501 tgaaaggtga tttgtagtga ttcaagttac tcttttcaca ataaaaattt catgattttc
     1561 ataaggagga aatcactaat ggtagttaaa gttggtatta acggtttcgg acgtatcggt
     1621 cgtcttgctt tccgtcgtat ccaaaacgta gaaggtgttg aagttacacg catcaacgac
     1681 cttacagatc cagttatgct tgcacacttg ttgaaatacg acacaactca aggtcgtttc
     1741 gacggtactg ttgaagttaa agaaggtgga tttgaagtta acggtaaatt cgttaaagtt
     1801 tctgctgaac gtgatccaga gcaaatcgac tgggctactg acggtgtaga aatcgttctt
     1861 gaagctactg gtttctttgc taagaaagaa gcagctgaaa aacaccttaa aggtggagct
     1921 aaaaaagttg ttatcactgc tcctggtgga aacgacgtta aaacagttgt attcaacact
     1981 aaccacgacg ttcttgacgg tactgaaaca gttatctcag gtgcttcatg tactacaaac
     2041 tgcttggctc caatggctaa agctcttcaa gataactttg gtgttgttga aggattgatg
     2101 actactatcc acgcttacac tggtgaccaa atgatccttg acggaccaca ccgtggtggt
     2161 gaccttcgcc gtgctcgcgc tggtgctgca aacatcgttc ctaactcaac tggtgctgct
     2221 aaagctatcg gtcttgtaat cccagaattg aacggtaaac ttgacggatc tgcacaacgc
     2281 gttccaactc caactggatc agttactgaa ttggtagcag ttcttgaaaa gaacgttact
     2341 gttgatgaag tgaacgcagc tatgaaagca gcttcaaacg aatcatacgg ttacacagaa
     2401 gatccaatcg tatcttcaga tatcgtaggt atgtcttacg gttcattgtt tgacgcaact
     2461 caaactaaag ttcttgacgt tgacggtaaa caattggtta aagttgtatc atggtacgac
     2521 aacgaaatgt catacactgc acaacttgtt cgtactcttg aatacttcgc aaaaattgct
     2581 aaataattct tgagttgata gaaagcaagg ctttgtggtc ttgcttttta tatagaaaaa
     2641 tggatgacac gatcatccat tcttttttaa ttctttttca aatgtatttg aaagggtagt
     2701 gaaagttagc ctctctaaag taagtgggtg ggtaaaggaa agtcggaagg catgaagcat
     2761 aagccggctt gtctttgatt tactattata gagagggtct cccaggatag gaagattatg
     2821 atgcaaaagg tgcacacgaa tctgatgggt tcgccctgtc tttagcttgc aatgagccaa
     2881 ggaagtcttg tttgagaatt gctttaatct gcttacatgc gtttcagcat attgcccatt
     2941 ttttgcatca actattcttt ttctacgatc atggcgatca cgtccaattt tgtctctgaa
     3001 aacaagttct tttctgttga tatttccatc aactagagcc caatattctc tagaaatctc
     3061 ttttttctcc aataagcgat tgagaatggg caggataaaa ggatttttgg caaagagaac
     3121 taagccactg gtttccatgt ccagacgatg aacgacatag caggtttggc caacataggt
     3181 actgacatgg ttaagaaggg caatttcgtt tggttgatta ccatgcgttt tcatcccctc
     3241 tggtttgttt acaataatca agtgttgatc ttgataaact tcctgcacta agtctgggtt
     3301 gccccaaggg atcgtctttt ggggataatc ttcctcgtca aaagtcaact ggcaaacatc
     3361 tccaggattt acgatttcgt tccagtggac ttcttcttga tttatcaaaa tatgtttctt
     3421 gattctcaaa aaatgacgga tttttctagg gatgaggagt tgttcctcaa gtaattgctt
     3481 taccgtcatt tgaggtatag aggcgggtaa tgtaaatgtg aattgcatac agatattgta
     3541 acaaaaaaag ccctatttgg ataggaaata gctaaattct tgtcttccta tgatgaagat
     3601 gataaaataa acgcatgaaa ttagataaat tatttgagaa atttctttct ctttttaaaa
     3661 aagaaacaag tgaactagag gactctgatt ctactatctt acgtcgctct cgtagtgatc
     3721 gaaaaaaatt agcccaagta ggtccgattc gaaaattctg gcgtcgttat catctaacaa
     3781 agattatcct tatactaggt ttgagtgcag gcttgctagt tggaatctat ttgtttgctg
     3841 tagccaagtc gaccaatgtc aatgatttgc aaaatgcctt gaaaactcgg actcttattt
     3901 ttgaccgtga agaaaaagag gctggtgcct tgtctggtca aaagggaacc tatgttgatc
     3961 tgactgatat cagtaaaaac ttgcagaatg ctgttattgc gacagaagac cgttctttct
     4021 ataaaaatga cgggattaac tatggccgtt tcttcttggc tattgtcact gctggacgtt
     4081 caggtggtgg ctctaccatt acccaacagc tggctaaaaa cgcctattta tcacaggatc
     4141 aaactgttga gagaaaagcg aaagaatttt tccttgcctt agaattaagc aaaaaatata
     4201 gtaaggagca aattctaacc atgtacctta acaacgctta ttttggaaat ggtgtgtggg
     4261 gtgtagaaga tgcgagtaag aaatactttg gagtttctgc atcagaagtg agtctggatc
     4321 aagctgcgac tctggcaggg atgctcaagg ggccggaact gtataatccc ttgaattccg
     4381 tagaagattc tactaatcgg cgcgatactg tcttgcagaa tatggttgca gcaggatata
     4441 ttgataaaaa ccaagaaacc gaagctgctg aagttgatat gacttcgcaa ttgcacgata
     4501 agtatgaagg aaaaatctca gattaccgtt acccctctta ttttgatgcg gtggttaatg
     4561 aagctgtttc caagtataat ctaacagagg aagagattgt caataatggc taccgcattt
     4621 acacagagct ggaccaaaac taccaagcaa atatgcagat tgtttatgaa aacacatcgc
     4681 tatttccgag ggcagaggat ggaacgtttg ctcaatcagg aagtgtagct ctcgaaccga
     4741 aaacaggggg agttcgtgga gttgtcggtc aagttgctga caatgataaa actggattcc
     4801 ggaatttcaa ctatgcaacc caatcaaagc gtagtcctgg ttctacaatt aagcctttag
     4861 ttgtttatac gccagcagtt gaagcaggct gggctttgaa taagcagttg gataaccata
     4921 ccatgcagta tgacagctat aaggttgata actatgcagg gatcaaaacg agtcgagaag
     4981 ttcctatgta tcaagccttg gcagaatcgc ttaatctacc tgctgttgcc actgttaatg
     5041 atttgggtgt cgacaaggct tttgaggcag gcgaaaaatt cggactcaac atggaaaagg
     5101 tcgaccgtgt tcttggtgtc gccttgggaa gcggtgttga aaccaaccct cttcaaatgg
     5161 ctcaagcata cgctgccttt gcaaatgaag gtttaatgcc tgaagctcat tttattagta
     5221 gaattgaaaa tgctagtgga caagttattg cgaatcataa aaattcacaa aaacgggtga
     5281 ttgataagtc tgtagctgac aagatgacca gtatgatgtt ggggactttc accaacggta
     5341 ccggtattag ttcatcgcct gcagactatg tcatggcagg gaaaactgga acaactgaag
     5401 cagttttcaa tccggagtac acaagtgacc agtgggtaat tggttatact ccggatgtag
     5461 tgattagcca ctggcttggc tttccgacca ctgatgaaaa tcactatcta gctggctcta
     5521 cttcaaacgg tgcagctcat gtctttagaa acattgccaa taccatttta ccttatacgc
     5581 caggaagtac ctttacggtt gaaaatgctt ataagcaaaa tggaattgca ccagccaata
     5641 caaaaagaca agtacaaacc aatgataata gccagacaga tgataatttg tctgatattc
     5701 gagggcgtgc gcaaagtcta gtagatgagg ctagccgggc tatctcagat gcgaagatta
     5761 aggaaaaggc tcaaacaata tgggattcga tagtcaatct atttcgctaa gatgcttgtc
     5821 aaagcctagc tttcttgtta taatggataa gatggaggcg ttatggcact aaaaaaagca
     5881 agcctagctt gtgcggtttg tggttcgaga aactattcaa tcaagatcag cggaaacccc
     5941 aagcctacac gactagaagt aaataaattt tgtaagcatt gtggcaagta cactacacac
     6001 agagaaacga gataggagag agcgatgcgt tttattggag atatttttag acttcttaaa
     6061 gacacaacat ggccaactcg caaggaaagc tggagagatt ttcgttctat catggaatac
     6121 acagctttct ttgtagtaat tatttacatt tttgaccagt tgattgtttc aggtttgatt
     6181 cgatttatta acatttttta gaagattagt ggagttaatt acactagaaa tcttctattt
     6241 atgaaaggaa atatcatgga tagttttgat aaaggatggt ttgttttaca aacttattct
     6301 ggttatgaaa ataaggtgaa agaaaatcta ttacaacgtg cacaaaccta caatatgttg
     6361 gataatattc tacgcgttga aattccaaca caaacagtgc aagttgaaaa aaatggaaag
     6421 agaaaagaag tagaagaaaa tcgctttcca ggttatgttc ttgtagaaat ggtcatgaca
     6481 gatgaagctt ggtttgttgt tcgaaacaca ccaaatgtta caggatttgt cggatcacac
     6541 gggaacagat caaaaccaac tccattattg gaacaagaaa ttcgtgacat tttggtatct
     6601 atgggacaaa ctgttcaaga atttgatttc gatgttgaga ttggtcaaac tgtacgtatt
     6661 attgatggtg cttttgcaga ctacactggt aagattacag aaattgataa taacaaagtg
     6721 aaaatgatta tctctatgtt tggtaatgac acagttgcag aagtaaacct aaaccaaatc
     6781 gcagaattat aa
//
LOCUS       DAVBOD010000083         6738 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 640-05
            SAMEA1012484-rid20186543.denovo.084, whole genome shotgun sequence.
ACCESSION   DAVBOD010000083 DAVBOD010000000
VERSION     DAVBOD010000083.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012484
            Sequence Read Archive: ERR059358
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6738)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6738)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979948.1
            Genome Coverage       :: 595x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:03:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,266
            CDSs (total)                      :: 2,219
            Genes (coding)                    :: 2,091
            CDSs (with protein)               :: 2,091
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 71 of 128
            Pseudo Genes (incomplete)         :: 50 of 128
            Pseudo Genes (internal stop)      :: 33 of 128
            Pseudo Genes (multiple problems)  :: 22 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6738
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012484-rid20186543.denovo.084"
                     /strain="NIG 640-05"
                     /db_xref="taxon:1313"
     gene            complement(67..927)
                     /locus_tag="VQ862_001991"
     CDS             complement(67..927)
                     /locus_tag="VQ862_001991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4299 domain-containing protein"
                     /protein_id="HET3116278.1"
                     /translation="MAKTFFIPNKQSILGEQEILNAKSILALLDGLESHSYDVVYLRQ
                     PLNRLEYIECAIVGQSQFLFKVSYADGQKAYRVDLPDLLTKTDWQIIKSFLDALLAYT
                     GTDIEGLDGFDFEAYFQASIQAYLADPVARFTICQGIFNPIFFSRENLKSFLEADGLA
                     QFEARVRAVQETDAYFARVSFYQDGEGKVHGVYHLAQGVKTVLPREPFVPAAYIEQLV
                     DKEVQWEIDLVQITGDGSKPEDYEAIARLDYAKFLEVLPLSFYHQLDANQIEVQPILD
                     KDFKALAQEE"
     gene            complement(1049..2035)
                     /locus_tag="VQ862_001992"
     CDS             complement(1049..2035)
                     /locus_tag="VQ862_001992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001030014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-related sulfurtransferase"
                     /protein_id="HET3116279.1"
                     /translation="MAKDIRVLLYYLYTPIENAEQFAADHLAFCKSIGLKGRILVADE
                     GINGTVSGDYETTQKYMDYVHSLPGMEELWFKIDEESEQAFKKMFVRYKKEIVHLGLE
                     DNDFDNDINPLETTGAYLSPKEFKEALLDKDTVVLDTRNDYEYDLGHFRGAIRPDIRN
                     FRELPQWVRDNKEKFMDKRVVVYCTGGVRCEKFSGWMVREGYKDVGQLHGGIATYGKD
                     PEVQGELWDGKMYVFDERIAVDVNHVNPTIVGKDWFDGTPCERYVNCGNPFCNRRILT
                     SEENEDKYLRGCSHECRVHPRNRYVSKNELTQAEVIERLAAIGESLDQAATV"
     gene            complement(2307..3782)
                     /locus_tag="VQ862_001993"
     CDS             complement(2307..3782)
                     /locus_tag="VQ862_001993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000800432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3502 domain-containing protein"
                     /protein_id="HET3116280.1"
                     /translation="MKNWKKYAFASASVVALAAGLAACGNLTGNSKKAADSGDKPVIK
                     MYQIGDKPDNLDELLANANKIIEEKVGAKLDIQYLGWGDYGKKMSVITSSGENYDIAF
                     ADNYIVNAQKGAYADLTELYKKEGKDLYKALDPAYIKGNTVNGKIYAVPVAANVASSQ
                     NFAFNGTLLAKYGIDISGVTSYETLEPVLKQIKEKAPDVVPFAIGKVFIPSDNFDYPV
                     ANGLPFVIDLEGDTTKVVNRYEVPRFKEHLKTLHKFYEAGYIPKDVATSDTSFDLQQD
                     TWFVREETVGPADYGNSLLSRVANKDIQIKPITNFIKKNQTTQVANFVISNNSKNKEK
                     SMEILNLLNTNPELLNGLVYGPEGKNWEKIEGKENRVRVLDGYKGNTHMGGWNTGNNW
                     ILYINENVTDQQIENSKKELAEAKESPALGFIFNTDNVKSEISAIANTMQQFDTAINT
                     GTVDPDKAIPELMEKLKSEGAYEKVLNEMQKQYDEFLKNKK"
     gene            complement(3866..4789)
                     /locus_tag="VQ862_001994"
     CDS             complement(3866..4789)
                     /locus_tag="VQ862_001994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001075101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HET3116281.1"
                     /translation="MAKKKIKKEKIDNVGIHSFSKKADIFFSIISGLIALSCILPFVF
                     VIIISVTDEKSLLQYGYSFFPSQFGLDGFEFLAQFKDKILQALFISVFVTVVGTLTNV
                     FITTTYAYAISRTTFKYRRFFTIFVLLSMLFNAGLVPGYIMVTRVLQLGDTVWALIVP
                     MLLSPFNIILMRSFFKKTIPEAILESARIDGASEARIFFQICLPLSLPGIATITLLTA
                     LGFWNDWFNALLYIKSDNLYPLQYLLMQIQQNMDYIAKAVGLTGQLGVALPKETGRMA
                     MVVVATLPIAILYPFFQRYFVKGLTIGGVKE"
     gene            complement(4803..5732)
                     /locus_tag="VQ862_001995"
     CDS             complement(4803..5732)
                     /locus_tag="VQ862_001995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000714575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HET3116282.1"
                     /translation="MKKFSKTLRDNWIFLLMVLPGTLWLILFFYIPVFGNVVAFKDYH
                     MTSNGFIDSIINSKWVGLDNFRFLFSSRDAFIITRNTVLYNLGFIFLGLVVSVGIAII
                     LSELRSKRMVKIFQTSMLFPYFLSWVIISFFTDAFLNIDKGVFNHLLESLGLKEVNFY
                     ADLGIWPYLLLFLGIWKGFGYSSVMYYATIMGIDPTYYEAATVDGASKWQRIRNVTIP
                     QLTPLVTVLTILAVGNIFRADFGLFYQIPHNAGQLYNVTNVLDVYVFNGLTQTADIGM
                     AAAAGLYQSVVGLILVILSNLLARRVDPNSALF"
     gene            complement(6051..6271)
                     /locus_tag="VQ862_001996"
                     /pseudo
     CDS             complement(6051..6271)
                     /locus_tag="VQ862_001996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809441.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(6225..6485)
                     /locus_tag="VQ862_001997"
     CDS             complement(6225..6485)
                     /locus_tag="VQ862_001997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3116283.1"
                     /translation="MTGVSNPTTDSARLVLAEAKKAFADDSLTEQGLRDILQTVKDAI
                     ASLESIKESQSATKDGGQTAGKETAGEDESANQTQEISQGIK"
BASE COUNT         1999 a         1356 c         1298 g         2085 t
ORIGIN      
        1 caatcctgtc tttcatggca ggatttttct atttcaaaaa agcaagtcga ttgacctgct
       61 tctgctttac tcttcttgtg ctaatgcttt aaaatctttg tctaatatgg gttgcacttc
      121 tatttgattg gcgtctagtt ggtggtaaaa agataggggt aatacctcta agaattttgc
      181 atagtccaag cgggcaatgg cttcatagtc ttctggttta gagccatctc ctgtgatttg
      241 aaccaagtca atctcccact gcacttcctt atccaccaat tgctcaatat aggctgcagg
      301 aacaaacggt tctctcggta aaactgtctt gactccttga gctagatggt aaacgccatg
      361 cacttttcct tctccatcct gatagaagga aactctcgca aagtaggcat ctgtctcttg
      421 aaccgcacgc acacgcgctt caaactgagc caagccatct gcctctaaaa agcttttcaa
      481 gttctcacga ctaaagaaaa taggattaaa aattccttgg caaatcgtaa aacgagctac
      541 agggtctgct agataggctt gaatacttgc ttggaaataa gcttcaaaat caaaaccatc
      601 tagcccttca atatcagtcc ctgtataagc aagcaaagca tctaaaaatg acttgataat
      661 ctgccagtct gtctttgtta gtaggtcagg aagatcgaca cggtaagcct tttgaccatc
      721 agcataactg accttaaaaa gaaattgtga ttgccccact atcgcacact caatatactc
      781 gagacgatta agaggctgac ggagatagac tacatcatag ctatgtgact ccaaaccgtc
      841 tagcaaggcc aagatcgact tggcattcaa aatctcttgt tctcctaaaa tgctctgttt
      901 atttggaata aaaaatgttt ttgccataac tggactcctt tgaaatcgtt tacatacagt
      961 ataccttatt tttctgaaag atacagaaac aaactttaga tttttgagta caaagcatag
     1021 aaaaacagcc cctgaggact gtttgatctt atacagtagc tgcttgatcc aagctttcac
     1081 cgatagcggc taggcgctca atcacttcag cttgtgtcaa ttcatttttt gaaacatagc
     1141 ggttacgtgg gtgaacacgg cactcgtgtg agcatccacg aaggtacttg tcttcatttt
     1201 cttctgatgt caagatacga cggttacaga atggatttcc acagttgaca taacgttcac
     1261 atggtgttcc atcaaaccag tctttcccta cgatagttgg gttgacatgg ttgacatcaa
     1321 cggcaatacg ctcgtcaaag acgtacattt tcccatccca aagctcacct tgaacttctg
     1381 ggtctttacc gtaagttgcg attcctccgt gcaattggcc gacatctttg taaccttcac
     1441 gaaccatcca gcctgagaat ttctcacagc gaacgccacc tgtacagtaa accacgacac
     1501 gcttgtccat gaatttttcc ttgttatcac ggacccattg tggtaactca cggaagttgc
     1561 gaatatctgg gcgaatagcc ccacggaaat gtcctaggtc atactcataa tcattacgtg
     1621 tgtcaaggac aacggtatct ttatcaagaa gcgcttcttt gaactctttt ggagacaagt
     1681 aagcacctgt tgtttcaagt gggttgatgt cattgtcaaa gtcgttgtct tccaaaccaa
     1741 ggtggacaat ttctttcttg tagcgaacaa acatcttctt gaaggcttgt tcactttctt
     1801 cgtcaatctt gaaccagagt tcttccattc ctggaaggct gtgaacgtag tccatgtatt
     1861 tttgagttgt ttcatagtca cctgaaactg ttccgttaat tccctcgtca gcgactagga
     1921 tacggccttt aagaccgatt gatttacaga aagccaagtg gtctgcagca aattgctctg
     1981 cattttcaat tggagtataa aggtagtaaa gtaagacacg aatatctttt gccataagat
     2041 ttgttctctt ttctattctt aaattttcta aattttttat ttatctacac tagtatacct
     2101 gcttgagaaa acgaatgcaa tttatttgac tggaaattgt agagggttct cgaaatttcc
     2161 tgaatggtta aaataaggac aagagaaaac atggatatct atatccttgt gccaaaaaaa
     2221 ccactgtctc ccccagacca acctgaggaa agcagtgatt cttattttag gagttaggaa
     2281 tgaatacacg aaatcaattt agctgattat tttttgtttt tcaagaattc atcgtattgt
     2341 ttttgcattt cgttcaatac tttttcgtag gcaccttcag atttcaattt ttccatcaat
     2401 tctggaatcg ctttatctgg gtctacagta ccagtgttga tagctgtatc aaattgttgc
     2461 attgtgttag caatagctga gatttcagat ttcacattgt cagtattgaa gataaatcca
     2521 agcgctggag attctttagc ttctgccaat tctttcttag aattttcgat ttgttggtct
     2581 gtaacgtttt cgttgatgta aaggatccag ttgttaccag tgttccatcc acccatgtga
     2641 gtgtttcctt tgtagccatc aagaacgcga acacggtttt ctttaccttc aattttttcc
     2701 cagttcttgc cttctggacc gtaaacaaga ccgttcaaga gttctggatt cgtattcaag
     2761 aggttcaaga tttccattga tttttctttg ttcttagagt tgtttgagat gacaaagtta
     2821 gcaacttgtg ttgtttggtt tttcttgatg aagttagtaa ttggtttgat ttggatatct
     2881 ttgttggcaa cacgtgaaag caagctgtta ccgtagtcag ctggtcctac tgtttcttca
     2941 cgaacgaacc aagtatcttg ttgaaggtca aaggaagtat cgcttgttgc gacgtctttt
     3001 ggaatgtagc cagcttcata gaatttgtga agagtcttca agtgttcttt gaaacgaggt
     3061 acttcgtaac ggtttacaac tttagtagta tcgccttcaa ggtcaataac gaatggaaga
     3121 ccgtttgcta ctgggtagtc aaagttatca gatgggatga aaactttacc aatagcaaat
     3181 ggtactacgt ctggagcttt ttctttgatt tgtttcaaga ctggctcaag agtttcgtaa
     3241 gaagtaacac ctgaaatatc gataccatat ttggcaagga gagttccgtt gaaggcaaag
     3301 ttttgagatg atgctacgtt ggctgcaact ggtacagcgt aaatcttacc atttacagta
     3361 ttacccttga tataagctgg atcaagtgcc ttgtaaaggt ctttaccttc ttttttgtac
     3421 aattctgtca agtcagcata agcacctttt tgagcattta caatatagtt atctgcaaag
     3481 gcgatatcat agttttcacc agatgatgtg ataactgaca ttttcttacc atagtcaccc
     3541 cagccaaggt attggatatc caatttagca ccaacttttt cttcgatgat tttgttggca
     3601 tttgctaaca attcatccaa gttatctggt ttgtcaccga tttggtacat tttgataaca
     3661 ggtttgtcac ctgaatcagc agcttttttg ctgttacctg tcaagttgcc acaagcagca
     3721 agacctgcag ccaaagcaac tacactagca gatgcaaaag catatttttt ccagtttttc
     3781 atgataaaaa ctcctttttt tatttttaaa cttataaaca atgtaatgat cttaacttca
     3841 cgcaagggaa gtttggaaac aagtgctatt ctttcacacc accgatagtc aaacctttta
     3901 caaagtagcg ttggaagaat ggatacaaaa tcgcgattgg aagggttgct accacaacca
     3961 tggccatacg acctgtttct ttcggtagag caactcccag ttgaccagtc aagccgaccg
     4021 ctttggcaat gtagtccata ttttgttgga tttgcatgag caaatattgc aatggataca
     4081 agttatcact cttgatgtaa agaagggcgt tgaaccagtc attccagaaa ccaagagctg
     4141 tcaaaagcgt gatggttgcg atacctggta gtgacaatgg caaacagatt tggaagaaaa
     4201 tccgggcctc actggcacca tcgatacgag ccgattcgag aatggcttct ggaatggtct
     4261 tcttgaagaa ggaacgcatc aagatgatat tgaatggtga gagaagcatt ggaacaatca
     4321 aggcccaaac agtgtcacca agctgaagta cacgggtcac catgatataa cctggtacca
     4381 aaccagcgtt gaacaacata ctgagaagga cgaagatggt aaaaaatctg cgatacttaa
     4441 aggttgtccg tgaaatagcg taggcatagg ttgttgtgat aaagacattt gtcaatgtcc
     4501 caactacggt tacaaagaca gagatgaaga gggcttgtag gattttatcc ttaaactgtg
     4561 ccaaaaactc aaaaccgtct aagccaaatt gggatgggaa gaagctatag ccgtattgga
     4621 ggaggctttt ctcgtctgtc actgaaataa tgataacgaa tacaaaaggt aggatacaag
     4681 agagggcaat caaacccgaa atgatactga agaagatatc tgctttctta ctgaaggagt
     4741 gaatgccgac attatcaatt ttttcttttt taattttctt ttttgccata ttctcctcct
     4801 ttctagaaca aagctgagtt tggatcgact cgtcttgcaa gcaagtttga taggataacc
     4861 agaatcaaac caacaacgga ttggtaaaga ccggctgctg cagccatacc gatatctgct
     4921 gtctgagtca aaccattaaa gacatatacg tccaaaacgt tggttacatt gtaaagctga
     4981 ccagcattgt gtgggatttg atagaagaga ccaaagtctg cgcggaagat atttccgact
     5041 gcaaggatgg tcaatacagt tacaagcgga gtcaactgag gaatggttac gttgcgaata
     5101 cgttgccact tgctagctcc gtccactgtc gctgcttcgt agtaggttgg atcaattccc
     5161 atgatcgtcg catagtacat gacactgcta tatccaaagc ctttccaaat acctaggaaa
     5221 agtaggagat agggccagat gcccaggtca gcgtaaaaat tgacttcttt gagaccaaga
     5281 ctttccaata gatgattgaa caccccttta tcaatattta ggaaggcatc tgtaaagaaa
     5341 ctgatgataa cccaagacaa gaagtaaggg aacaacatag aagtttggaa aatcttcacc
     5401 attctcttag aacggagctc gctgaggata atggcaatcc ctacagatac aactaaacct
     5461 agaaagataa agccaagatt gtagaggaca gtatttcgtg tgataataaa ggcgtctctt
     5521 gaactaaata agaatctgaa attatcgagt ccgacccatt tactatttat gatactatct
     5581 atgaaaccat tactggtcat gtggtagtct ttgaaggcaa ccacgttccc aaatactgga
     5641 atgtaaaaga atagaatcaa ccagagtgtc cctggcaaaa ccatcaagag aaagatccag
     5701 ttgtctctca atgtttttga aaactttttc ataatttcct ccctttttat tttgatatcc
     5761 atctaaaaat tcttttttag acttttgata acgattacat tattagtata ctcctatttg
     5821 caggttaggt taaactccta attatagaaa aaactccaca aattatgtag cagatttaaa
     5881 actttatcac cactatcaaa caaatgtcct aaatcaattg tttattttat ctctattagc
     5941 ccagtgatgg cgtcactctg ttataagcat ccaacaacgg ggtatactga aaaatctcca
     6001 gactagggaa ctcagagata gttcctaatc tggagatttt taatatgtta ttaggcgttt
     6061 gctttcaact tagcaataac ctctttaaga ttatcaatca cctctgcttc agtatgctca
     6121 gagctttttc atctgccaag aacaaaactg ctttttgaag ttctttttga gagttttcaa
     6181 ggacatcctt atctactgtt tcaaggtttg agtctttaag aagtttactt aattccttgg
     6241 ctaatttctt gagtttgatt tgcagactca tcttctcctg ctgtttcttt gcccgctgtt
     6301 tgtcctccat ccttagttgc tgactggctt tccttaatgg actctaggga agcaatggca
     6361 tctttgactg tttgcaaaat atcacgtaaa ccttgctctg tcaaactatc atctgcaaaa
     6421 gctttcttag cctctgccaa aaccagacgt gctgaatctg tggtaggatt cgatacacct
     6481 gtcaatgatc tcaaaagatt ttctaaggtt tgagtctgct tactaatact agactaaaat
     6541 caaaaagcat tatataacag tgatatgaaa tcaactaaag aagaaatcca aactatcaaa
     6601 acacttttaa aagactctcg tacagctaaa tatcataaac gccttcaaat cgttctatag
     6661 taaaatgaaa caagaacagg acaaatcgat caggacagtc aaatcgattt ctaacaatgt
     6721 tttagaagta gatgtgta
//
LOCUS       DAVBOD010000084         6726 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 640-05
            SAMEA1012484-rid20186543.denovo.085, whole genome shotgun sequence.
ACCESSION   DAVBOD010000084 DAVBOD010000000
VERSION     DAVBOD010000084.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012484
            Sequence Read Archive: ERR059358
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6726)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6726)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979948.1
            Genome Coverage       :: 595x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:03:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,266
            CDSs (total)                      :: 2,219
            Genes (coding)                    :: 2,091
            CDSs (with protein)               :: 2,091
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 71 of 128
            Pseudo Genes (incomplete)         :: 50 of 128
            Pseudo Genes (internal stop)      :: 33 of 128
            Pseudo Genes (multiple problems)  :: 22 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6726
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012484-rid20186543.denovo.085"
                     /strain="NIG 640-05"
                     /db_xref="taxon:1313"
     gene            138..860
                     /locus_tag="VQ862_001998"
     CDS             138..860
                     /locus_tag="VQ862_001998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HET3116284.1"
                     /translation="MRLDKFLVACAVGSRTEVKNLLKAGRVTVNGKKEKSAKLQIDEK
                     IDEIRFDGQVLEYEEFVYYMMNKPKGVISATEDPKHRTVLDLLDDLARSKEVFPVGRL
                     DIDTHGLLLLTNDGQLAHVLLSPKRHVDKTYLAQVKGIMTQEDVETFAEGIPLKDFTC
                     QPAILELVSIDTEKNQSQIRVTIAEGKFHQIKRMVGYCGKEVVDLQRLTMGTLVLDEN
                     LERGEWRRLTKEELEILRANII"
     gene            1077..2411
                     /gene="pepC"
                     /locus_tag="VQ862_001999"
     CDS             1077..2411
                     /gene="pepC"
                     /locus_tag="VQ862_001999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000991632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase C"
                     /protein_id="HET3116285.1"
                     /translation="MNAIQESFTDKLFANYEANVKYQAIENAASHNGIFAALERRQSR
                     VDNTPVFSLDLTKDKVTNQKASGRCWMFAALNTFRHKLISQYKLENFELSQAHTFFWD
                     KYEKSNWFLEQVIATSDQELTSRKVSFLLQTPQQDGGQWDMVVSLFEKYGVVPKSVYP
                     ESVSSSSSRELNAVLNKLLRQDAQILRDLLVSGADQVTVQAKKEDLLQEIFNFLAMSL
                     GLPPRKFDFAYRDKDNNYKSEKGITPQEFYKKYVNLPLEDYVSVINAPTADKPYGKSY
                     TVEMLGNVVGSRAVRYINVPMERLKELAIAQMQAGETVWFGSDVGQLSNRKAGILATD
                     VYDFESSMDIKLTQDKAGRLDYSESLMTHAMVLTGVDLDENGKSTKWKVENSWGDKVG
                     TDGYFVASDAWMDEYTYQIVVRKELLTAEEQAAYGAEPIVLAPWDPMGALAE"
     gene            complement(2467..3378)
                     /locus_tag="VQ862_002000"
     CDS             complement(2467..3378)
                     /locus_tag="VQ862_002000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HET3116286.1"
                     /translation="MTEKLQLTKSDRKKVWWRSTFLQGSWNFERMQNLGWAYTLIPAI
                     KKLYTKKEDQIAALERHLEFFNTHPYVAAPVMGVTLALEEERANGVEIDDAAIQGVKI
                     GMMGPLAGIGDPVFWFTVRPILGSLGASLALTGNILGPLLFFVAWNLIRMSFLWYVQE
                     IGYKAGSEITKDMSGGILQDITKGASILGMFILAVLVQRWVNIKFAFDVSKVQLDEKA
                     YIHWDKLPEGSKGIQEAFAQVGQGLSQTPEKVTTFQQNLDMLIPGLSGLLLTLLCMYL
                     LKKKVSPITIILALFAVGIVAHVLHIM"
     gene            complement(3402..4205)
                     /locus_tag="VQ862_002001"
     CDS             complement(3402..4205)
                     /locus_tag="VQ862_002001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter subunit
                     IIC"
                     /protein_id="HET3116287.1"
                     /translation="MSIISMVLVVVVAFFAGLEGILDQFQFHQPLVACTLIGLVTGHL
                     EAGIILGGSLQMIALGWSNIGAAIAPDAALASVAAAIIMVLGGDFTKTGIGVAQAVAI
                     PLAVAGLFLTMIVRTISVGLVHTADAAAKKGDFGAVERAHFIALLFQGLRIALPAALL
                     LMVPTETVQSILSAMPDWLKDGMAIGGGMVVAVGYAMVINMMATREVWPFFALGFVLA
                     AVSDITLIGFGAIGVAIALIYLHLSKTGGNGGGGAATSNDPIGDILEDY"
     gene            complement(4233..5222)
                     /gene="manX"
                     /locus_tag="VQ862_002002"
     CDS             complement(4233..5222)
                     /gene="manX"
                     /locus_tag="VQ862_002002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000021981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIAB"
                     /protein_id="HET3116288.1"
                     /translation="MSIGIIIASHGEFAAGIHQSGSMIFGEQEKVQVVTFMPNEGPDD
                     LYAKFNNAVAAFDAEDEVLVLADLWSGSPFNQASRVMGENPERKFAIITGLNLPMLIQ
                     AYTERLMDAAAGVEKVAANIIKEAKDGIKALPEELNPVEEVASAAAAPVAQTAIPEGT
                     VIGDGKLKINLARLDTRLLHGQVATAWTPDSKANRIIVASDNVAKDDLRKELIKQAAP
                     GNVKANVVPIQKLIEISKDPRFGETHALILFETPQDALRAIEGGVPIKTLNVGSMAHS
                     TGKTLVNTVLSMDKEDVATFEKMRDLGVEFDVRKVPNDSKKDLFDLINKANVK"
     gene            complement(5455..6474)
                     /gene="adhP"
                     /locus_tag="VQ862_002003"
     CDS             complement(5455..6474)
                     /gene="adhP"
                     /locus_tag="VQ862_002003"
                     /EC_number="1.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase AdhP"
                     /protein_id="HET3116289.1"
                     /translation="MKAVVVNPESTGVAIEEKVLRPLETGEALVEVEYCGVCHTDLHV
                     AHGDFGQVPGRVLGHEGIGIVKEIAPDVKSLKVGDRVSVAWFFEGCGTCEYCTTGRET
                     LCRTVKNAGYSVDGGMAEQCIVTADYAVKVPDGLDPAQASSITCAGVTTYKAIKEAKI
                     EPGQWVVLYGAGGLGNLAVQYAKKVFNAHVIAVDINNDKLALAKEVGADIVINGLEVE
                     DVAGLIKEKTDGGAHSAVVTAVSKVAFNQAVDSIRAGGRVVAVGLPSEMMELSIVKTV
                     LDGIQVIGSLVGTRKDLEEAFQFGAEGLVVPVVQKRPVEDAVAIFDEMEKGQIQGRMV
                     LDFTH"
BASE COUNT         2017 a         1388 c         1478 g         1843 t
ORIGIN      
        1 agatagaact gacgaagtca gtaacatata tacggcaagg cgacgttgac gcggtttgaa
       61 gagatttttg aagagtatga aacgaaaagg aggttggtca ttgtactagc ctccttttga
      121 tatgatataa tagttctatg agattagata aatttttagt tgcctgtgcg gtgggaagtc
      181 ggactgaggt caaaaacttg ctcaaggctg ggcgcgtgac tgtaaatggt aaaaaagaaa
      241 aatcagctaa attgcagatt gatgaaaaaa tagatgagat tcgctttgat gggcaagtgt
      301 tggagtatga agagtttgtc tactacatga tgaacaagcc caaaggagtt atctcagcga
      361 ctgaggatcc caagcacaga accgttctgg acttgttgga tgacttggcg cggagtaagg
      421 aagttttccc agtaggacgc ttggatattg acacgcatgg tcttttgctc ttgaccaatg
      481 atggtcagct ggctcatgtt cttctttcgc ccaagcgtca tgtggacaag acttatctgg
      541 cacaagtcaa gggaatcatg acccaagaag atgtggagac atttgctgag ggtattcctc
      601 tcaaagactt tacctgtcaa cccgctatac tggagcttgt atccatagat acagaaaaga
      661 atcaaagcca aatccgtgtg accattgcag aagggaagtt tcatcagatc aagcgtatgg
      721 tgggctactg tggcaaggaa gtggtggact tgcaacgatt gactatggga actttagtat
      781 tagatgagaa cctggaacga ggggaatggc gtcgcttgac caaggaagaa ttagaaattc
      841 tccgcgctaa tattatttaa tttagtttaa tactcaatga aaatcaaaga gcaaactagg
      901 aaactagccg caggctgtac ttgagtacgg caaggcgacg ttgacgtggt ttgaagagat
      961 tttcgaagag tataaattcg aaaaaggtga gggacaatgt cctcgccttt tatgtttttt
     1021 agttgcttcc tttgtgaaaa gagttataat agactgtaga ataaaaggag gaatctatga
     1081 acgcgattca agaatcattt actgataaac tatttgccaa ctatgaagca aatgtaaaat
     1141 accaagcgat tgaaaatgct gccagccaca acggaatttt tgcagctctg gaacgtcgcc
     1201 aaagccgtgt agacaacaca cctgttttct cattggattt aaccaaggac aaggtcacta
     1261 accagaaagc gtctggtcgt tgctggatgt ttgcggctct caacaccttc cgccacaaac
     1321 tcatctcgca atacaaattg gagaactttg agttgtcaca agcccacact ttcttctggg
     1381 ataagtatga gaaatcaaac tggttcttgg agcaagtcat tgcgacttca gaccaagaat
     1441 tgactagccg caaggttagc ttcttactcc aaacacctca acaagatggc ggtcaatggg
     1501 atatggtcgt ttccctcttt gaaaaatacg gtgtcgtgcc taagtcagtt tatcctgagt
     1561 ctgtttcatc tagcagcagt cgtgagctaa atgcggtcct taataaattg cttcgtcaag
     1621 atgctcaaat cttgcgtgat ttgcttgttt ctggtgcaga tcaagtgact gttcaagcta
     1681 agaaagaaga cctcttgcaa gaaatcttta actttcttgc tatgtcatta ggacttccac
     1741 cacgcaagtt tgactttgct tatcgcgata aagataacaa ctacaaaagt gaaaaaggaa
     1801 tcacaccaca agagttctac aagaaatatg tcaatcttcc tttagaagac tacgtttctg
     1861 ttatcaatgc tccaactgct gataaacctt acggaaaatc ttacacagtt gagatgttgg
     1921 ggaatgtggt tggtagccgt gcagttcgtt acatcaacgt tccaatggag cgcttgaaag
     1981 aattggcgat tgcccaaatg caagcaggtg agactgtttg gtttggttct gatgtcggcc
     2041 agctcagtaa ccgtaaggct ggaatccttg cgacagatgt ttatgacttt gaatcaagca
     2101 tggacattaa acttactcaa gacaaggctg gacgtttgga ctatagcgaa agcttgatga
     2161 cccacgccat ggtcttgaca ggtgttgact tggacgaaaa tggtaaatca accaagtgga
     2221 aggttgaaaa ctcatgggga gacaaggtcg gtacagatgg ttactttgtt gcctcagacg
     2281 cttggatgga cgaatacaca taccaaatcg ttgttcgtaa ggaattgctg acagcagaag
     2341 aacaagctgc ctatggagca gaaccaattg tacttgcacc atgggatcca atgggagcct
     2401 tggctgaata aaagcataga aaaaaggaat cagattttag aacctggttc ctttttagtt
     2461 gcttgattac atgatgtgaa gaacatgtgc cacaataccc actgcgaaga gagcaaggat
     2521 aatagtgatt ggagatactt ttttcttaag taagtacatg caaagtaaag taaggagtag
     2581 tcctgataat ccaggaatca acatatccaa gttttgttgg aaagtagtaa ctttttcagg
     2641 agtttgagac aatccttgtc ctacttgtgc gaatgcttct tggatacctt tagacccttc
     2701 tggcaattta tcccaatgga tataagcctt ttcatctagt tgaactttag aaacatcgaa
     2761 agcaaattta atatttaccc agcgttgaac aaggacagca agaatgaaca tcccaaggat
     2821 agaagctcct ttagtgatat cttgaaggat accaccagac atatctttag tgatttctga
     2881 tccagcctta tatccaatct cttgaacata ccacaagaat gacatacgaa tcaagttcca
     2941 tgcaacaaag aagaggagtg gacccaagat attgccagta agggcaagtg aagcaccgag
     3001 agatccaagg attgggcgca ctgtaaacca gaatactggg tcaccgatac cagcaagagg
     3061 tcccatcata ccgattttaa ccccttggat agcagcgtca tcgatttcca caccgttagc
     3121 acgttcttct tcaagcgcaa gagtaacccc catgactgga gcagctacgt atggatgagt
     3181 gttgaagaac tcaaggtgac gctcaagagc agcgatttga tcttcttttt tagtatagag
     3241 ttttttgata gctggaatga gtgtataagc ccagcccaag ttttgcatcc gttcaaagtt
     3301 ccaagaccct tgtaagaagg ttgaacgcca ccaaactttt ttacgatctg atttagttaa
     3361 ttgaagtttt tcagtcatga tgttttcagt cctttcttat cttagtagtc ttctaggata
     3421 tcgccgattg ggtcgttaga agttgcggct cctccgccac catttccacc agttttagaa
     3481 aggtgaaggt agataagagc gatagcaacg ccgatagcac cgaatccgat tagagtaata
     3541 tctgacacag cagcgagaac gaaaccaaga gcgaagaatg gccatacttc acgagttgcc
     3601 atcatgttga taaccatggc gtaaccaacg gcaacgacca taccaccacc gatagccata
     3661 ccatctttga gccagtctgg catggcacta aggatacttt gtacagtttc agttggtacc
     3721 ataaggagaa gagctgcagg aagcgcgata cgaagtcctt ggaaaagtag cgcgatgaaa
     3781 tgcgcacgct ccacagcgcc gaagtcacct tttttagcgg cagcatctgc agtatgaacc
     3841 aaaccaactg aaattgtacg aacaatcatt gtcaagaaaa gtccagctac agcaagaggg
     3901 atagcaaccg cttgggcaac accgatacca gtcttggtaa agtcaccacc aagaaccatg
     3961 ataatggcag cagcgacaga agcaagtgca gcatcaggag cgatagcagc accgatattt
     4021 gaccaaccaa gggcaatcat ttgaagcgat ccaccgagga taatccctgc ttccaagtga
     4081 cctgttacaa gcccaataag ggtacaggct acaagtggtt ggtgaaattg gaactggtcg
     4141 aggatgcctt caagacctgc aaagaaggct acaacgacta ctaaaaccat agaaataata
     4201 gacatgttta aaatcctttc ataaataatg gcttatttga cattggcttt gttaatcaag
     4261 tcaaacaaat cttttttaga atcatttggt actttacgga catcaaattc aacacccaag
     4321 tcacgcattt tttcaaatgt agcaacgtct tctttgtcca tagacaaaac ggtattgacc
     4381 aatgttttac ctgttgagtg agccatagaa ccaacattaa gagtcttgat tggcacgccg
     4441 ccttcgatgg cacgaagggc atcttgaggt gtttcaaaca agataagggc atgtgtttct
     4501 ccaaaacgtg ggtcttttga aatctcaatc agtttttgaa ttggaaccac gttagccttg
     4561 acattacctg gagctgcttg tttaatcaat tctttacgaa ggtcgtcttt agccacgtta
     4621 tctgaagcaa cgatgatacg atttgctttt gaatctggag tccaagcagt tgcaacctga
     4681 ccgtgaagta gacgtgtgtc aagacgggca agattgattt tcaatttacc gtctccgata
     4741 acagttcctt ctgggatagc agtttgggca actggagcag ctgcagcgct tgcaacttct
     4801 tcgactggat ttagctcttc tggaagagct ttgatgccat ctttggcttc tttaatgata
     4861 ttagcagcga ctttttctac acctgcagca gcgtccatga ggcgctctgt gtaggcttga
     4921 atcaacatcg gtaagttaag tcctgtgatg atggcaaact tacgctcagg attttctccc
     4981 atcacgcgac tagcttggtt aaatggagaa ccactccaaa ggtcagccaa aactagaacc
     5041 tcatcttctg cgtcaaatgc agcaacagcg ttattaaact tagcgtatag atcatcagga
     5101 ccttcatttg gcataaaggt cacaacttga accttttctt gttcaccaaa gatcatagat
     5161 cctgactgat gaatacccgc agcaaattcg ccgtggctcg caataatgat tccgatactc
     5221 attattgtca ttcctccttt tttgttttag ttttcattta agaaaacttt aagactgttt
     5281 aagtataaac cgttttcata aaaaaagcaa ctatttatca taaaaaatta aaaaattttt
     5341 atttttgtat gttgatatgt tgagtttttg aggagtaatc ttgaattctt atttaaaatt
     5401 taatataaaa aagttggaag aagcttccaa cttttaaaat aggtttctat tagattagtg
     5461 ggtgaagtcg agtaccatac gtccttggat ttggcctttt tccatttcgt cgaaaatggc
     5521 aacagcatct tctactggac gtttttgaac aactgggact accagacctt ctgcaccaaa
     5581 ttggaaggct tcttctaagt ctttacgagt tccgacaaga gaaccgatga cttggattcc
     5641 atcgaggact gttttaacga tgctgagttc catcatttca gaaggaagac caacagcgac
     5701 gacgcgacca ccagcacgaa tggagtcaac agcctggttg aaggcaactt tagacacagc
     5761 agttacgaca gctgaatgag ctcctccatc agttttttct ttaatgagtc cagctacatc
     5821 ttcaacttcg aggccgttaa tcacaatgtc agcgcctact tcttttgcaa gggcaagttt
     5881 gtcattgttg atatcgactg cgataacatg agcattgaat acttttttag cgtattgaac
     5941 agcgaggtta ccaagtccac cagcaccgta aagaacaacc cattggcctg gttcaatttt
     6001 tgcttctttg atagctttat aggttgttac tccagcacat gtgatagaag aagcttgggc
     6061 tggatcaagt ccgtcaggaa ctttgacagc atagtcagca gttacgatac attgttcagc
     6121 cataccaccg tctactgagt agccagcatt tttcactgta cggcaaaggg tttcgcgacc
     6181 agttgtacag tattcgcaag tgccacatcc ttcaaagaac caagcaacgc tgacgcggtc
     6241 accgacttta aggcttttca catctggagc aatctcttta acgataccga taccttcgtg
     6301 cccaagaaca cgtcctggga cttgaccaaa gtcaccatga gcaacgtgga ggtcggtgtg
     6361 gcaaacacca cagtattcaa cttctacaag tgcttcccca gtttcaagtg gacggagtac
     6421 tttttcttca atagcaacac cagtgctttc tggatttaca acaacagctt tcatagctat
     6481 cctccttgat attgaccgag aacagggaca acgggactgg attgattttt tgtcaacaga
     6541 gtcgagtgtg acgagctctc ttgtatttat atgtgaagta tatcacaaaa gaaagccttt
     6601 tccaaggttt tggagacaaa aagtagaaca atcgattaac tggttgatga gactgtgaaa
     6661 agagcacaaa gaccagcttg caagctggtc atactcttcg aaaatctctt caaaccacgt
     6721 cagctt
//
LOCUS       DAVBOD010000085         6678 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 640-05
            SAMEA1012484-rid20186543.denovo.086, whole genome shotgun sequence.
ACCESSION   DAVBOD010000085 DAVBOD010000000
VERSION     DAVBOD010000085.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012484
            Sequence Read Archive: ERR059358
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6678)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6678)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979948.1
            Genome Coverage       :: 595x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:03:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,266
            CDSs (total)                      :: 2,219
            Genes (coding)                    :: 2,091
            CDSs (with protein)               :: 2,091
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 71 of 128
            Pseudo Genes (incomplete)         :: 50 of 128
            Pseudo Genes (internal stop)      :: 33 of 128
            Pseudo Genes (multiple problems)  :: 22 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6678
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012484-rid20186543.denovo.086"
                     /strain="NIG 640-05"
                     /db_xref="taxon:1313"
     gene            complement(298..477)
                     /locus_tag="VQ862_002004"
     CDS             complement(298..477)
                     /locus_tag="VQ862_002004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001209433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3116290.1"
                     /translation="MREVIQELLDSSMSTSAISQGAGVPWTTVSDLRKGKTSMDKMAL
                     LTAEKLYEFATTDKQ"
     gene            complement(619..768)
                     /locus_tag="VQ862_002005"
     CDS             complement(619..768)
                     /locus_tag="VQ862_002005"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3116291.1"
                     /translation="MNKEDWLRLLEKAIDNIPETVTAIASLVTAITVARQNKKRKPKS
                     RQRKR"
     gene            1050..1517
                     /locus_tag="VQ862_002006"
     CDS             1050..1517
                     /locus_tag="VQ862_002006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside deaminase"
                     /protein_id="HET3116292.1"
                     /translation="MYYTLEEKEVFMREALREAEIALEHDEIPIGCVIVKDGEIIGRG
                     HNAREELQRAVMHAEIMAIEDANLSEESWRLLDCTLFVTIEPCVMCSGAIGLARIPNV
                     VYGAKNQKFGAAGSLYNILTDERLNHRVEVEIGILEDECAAIMQDFFRNRRKK"
     gene            1550..1647
                     /gene="ffs"
                     /locus_tag="VQ862_002007"
     ncRNA           1550..1647
                     /ncRNA_class="SRP_RNA"
                     /gene="ffs"
                     /locus_tag="VQ862_002007"
                     /product="signal recognition particle sRNA small type"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00169"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00169"
     gene            1704..2147
                     /locus_tag="VQ862_002008"
     CDS             1704..2147
                     /locus_tag="VQ862_002008"
                     /EC_number="3.6.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dUTP diphosphatase"
                     /protein_id="HET3116293.1"
                     /translation="MKIRGFELVSSFTDENLLPKRETAHAAGYDLKVAVRTVVAPGEI
                     VLVPTGVKAYMQPTEVLYLYDRSSNPRKKGLVLINSVGVIDGDYYGNPGNEGHIFAQM
                     KNITDQEVVLEVGERIVQAVFATFLIADGDAADGVRTGGFGSTGH"
     gene            2149..2664
                     /locus_tag="VQ862_002009"
     CDS             2149..2664
                     /locus_tag="VQ862_002009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HET3116294.1"
                     /translation="MKIIFVRHGEPDYRELEERSYIGFGIDLAPLSEMGRQQVQKLSK
                     NPLLSSAEIIVSSAVTRALETASYVVCATGLPLRVEPLLHEWQVYKTGIENFETARRL
                     FLENKGELLPNSPIQYETATEMKSRFLECMSKYREHQTVVVVAHRMLMRQFVPNEKID
                     FCQVIECELEI"
     gene            2678..4039
                     /gene="radA"
                     /locus_tag="VQ862_002010"
     CDS             2678..4039
                     /gene="radA"
                     /locus_tag="VQ862_002010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000336571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadA"
                     /protein_id="HET3116295.1"
                     /translation="MAKKKATFVCQNCGYNSPKYLGRCPNCGSWSSFVEEVEVAEVKN
                     ARVSLTGEKTKPMKLAEVTSINVNRTKTEMEEFNRVLGGGVVPGSLVLIGGDPGIGKS
                     TLLLQVSTQLSQVGTVLYVSGEESAQQIKLRAERLGDIDSEFYLYAETNMQSVRAEVE
                     RIQPDFFIIDSIQTIMSPEISGVQGSVSQVREVTAELMQLAKTNNIAIFIVGHVTKEG
                     TLAGPRMLEHMVDTVLYFEGERHHTFRILRAVKNRFGSTNEIGIFEMQSGGLVEVLNP
                     SQVFLEERLDGATGSSIVVTMEGTRPILAEVQALVTPTMFGNAKRTTTGLDFNRASLI
                     MAVLEKRAGLLLQNQDAYLKSAGGVKLDEPAIDLAVAVAIASSYKDKPTNPQECFVGE
                     LGLTGEIRRVNRIEQRINEAAKLGFTKIYVPKNSLTGITLPKEIQVIGVTTIQEVLKK
                     VFA"
     gene            4112..4609
                     /locus_tag="VQ862_002011"
     CDS             4112..4609
                     /locus_tag="VQ862_002011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007285146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbonic anhydrase"
                     /protein_id="HET3116296.1"
                     /translation="MSYFEQFMQANQAYVALHGQLNLPLKPKTRVAIVTCMDSRLHVA
                     QALGLALGDAHILRNAGGRVTEDMIRSLVISQQQMGTREIVVLHHTDCGAQTFENEPF
                     QEYLKEELGVDVSDQDFLPFQDIEESVREDMQLLIESPLIPDDVIISGAIYNVDTGSM
                     TVVEL"
     gene            4634..4828
                     /locus_tag="VQ862_002012"
     CDS             4634..4828
                     /locus_tag="VQ862_002012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3116297.1"
                     /translation="MKKSSILLLCIGLQYETIYYTDGSRSGAEYGLMGISIFLALFYM
                     IPALYFLFRIGKNGNCQRRF"
     gene            4810..5433
                     /locus_tag="VQ862_002013"
     CDS             4810..5433
                     /locus_tag="VQ862_002013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PrsW family intramembrane metalloprotease"
                     /protein_id="HET3116298.1"
                     /translation="MPKKVLILSLLGGMFLSGWLSSFANTYIHDLLGVLFPDSTFLNA
                     FESAIVAPLVEEPLKLLPLVFVLALIPVRKLKSLFLLGIASGLGFQMIEDIGYIRTDL
                     PEGFDFTISRILERIISGIASHWTFSGLAVVGVYLLYRAYKGQKVGKKQGLIFLGLAL
                     GTHFLFNSPFVELETELPLAIPVVTAIALYGFYHAYCFVEKHNELMT"
     gene            5578..6546
                     /locus_tag="VQ862_002014"
     CDS             5578..6546
                     /locus_tag="VQ862_002014"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006149122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HET3116299.1"
                     /translation="MSFSDLKLFALSSNKELAERVAQEIGIELGKSSVRQFSDGEIQV
                     NIEESIRGKHVFILQSTSSPVNDNLLEILIMVDALKRASAESVNVVMPYYGYARQDRK
                     ARAREPITSKLVANMLEVAGVDRLLTIDLHAAQIQGFFDIPVDHLMGAPLIADYFERR
                     GMVGSDYVVVSPDHGGVTRARKLAEFLKTSIAIIDKRRSVDKMNTSEVMNIIGKVEGK
                     TCILIDDMIDTAGTICHAADALAEAGAVEVYASCTHPVLSGPATDNIQKSAIKKLVVL
                     DTIYLPEERLIDKIEQISIAHLLGDAIVRIHEKRPLSPLFDIEKKI"
BASE COUNT         1843 a         1142 c         1604 g         2089 t
ORIGIN      
        1 gccagatggc ttgattacag ttaaataaat agaaaggaaa ctttctaaat tgttctttca
       61 ccgcaggctc aggcttgcgg tttttttgtt tgtctgaatc aagaaagcgt ctaaccaacc
      121 gacaccaatg tcggtagcaa aataaatggt ttgcctaaaa aattagagtt aagttctatt
      181 tttcaaaaac acgcattttg aacgattaga aacagaaatc taaatcctat tgttcaaaaa
      241 aacgtttaca tgaaaaatag ggaggtgttt tgttaaaaat aaaaacagtg atcgaaatca
      301 ctgcttatca gttgtagcaa attcataaag tttttctgct gtgagaagtg ccattttgtc
      361 catgcttgtt tttccttttc tgaggtcaga aacagtagtc catggaactc cagcaccttg
      421 ggaaatagca gatgtagaca tcgaactgtc taacaattct tgaataactt ctctcatctt
      481 atttgtcctt tttatttttt agataaatat atacattgat tgcaattata aaaatagcta
      541 ttgcactaac cattgcattt cctctttcca tttgataaaa tagaggtgta aggggctttc
      601 gccccaacct cttagcgttt acctttttct ttgacgggat ttcggtttac gctttttgtt
      661 ttgccttgcg accgttattg cggtcactag acttgcgata gcagttaccg tttcaggaat
      721 attgtctatt gccttttcaa gtaacctgag ccaatcttct ttgttcaact tcatcacccc
      781 ctttccttat cttgattata ttatatcacg gcacaccgag aaagtcaagc gttttgatga
      841 agtttttttt aattttttca aaaaaaaata gaccttgtcc agaggtcggg gagttggagg
      901 gggcaccctc caaaagcatt gatttaataa ggttttattt tacctttttc ataataatct
      961 ccctatagag tcaccgcatt cggtggcttt ttttgtgttg ggattcatga tataataata
     1021 aaatcgataa gtaggaaaag agaaaagaga tgtattatac gcttgaagaa aaagaagtct
     1081 ttatgaggga ggctttgaga gaggctgaga ttgctcttga acacgatgaa attccaattg
     1141 gttgtgtgat tgtcaaagat ggggaaatca ttggtcgtgg gcataatgcg cgtgaggaat
     1201 tacagcgagc ggttatgcat gcggaaatta tggctataga ggatgcgaac ttgagtgagg
     1261 agagctggcg cttgctggat tgcacacttt ttgtgaccat tgaaccttgt gtcatgtgta
     1321 gtggagcgat tgggcttgcc cgcattccaa atgtggtcta tggggctaaa aaccagaaat
     1381 ttggcgctgc tgggagtttg tacaatatct tgacagatga gcgtctcaat catcgtgtgg
     1441 aggttgaaat aggaattttg gaagatgaat gcgcagctat catgcaggat ttttttagaa
     1501 atagacggaa aaaataattt tgcttttaaa atgaatagga atgtgatata ataaatagtg
     1561 gagcaacagt tctgcgtgaa gcgggtcagg ggaggaatcc agcagcccta agcgatttga
     1621 attgtgtgct ctttttttcg tgctttttcc gaataaataa gatagaataa tctagaataa
     1681 atgataatag aaaagagaaa attatgaaaa ttcgtggttt tgaattggtt tcgagtttta
     1741 cagatgaaaa tttattgccc aagcgtgaga cagcgcatgc ggctggttac gacttaaagg
     1801 ttgctgtgcg tacagttgtt gcgccaggag agattgtctt ggttccgaca ggggttaagg
     1861 cttatatgca gccgactgag gttctctacc tctatgatcg ttcttcaaat cctcgtaaga
     1921 agggcttggt tttaattaac tcagttgggg tcattgatgg ggattattat ggaaatcctg
     1981 gaaatgaagg gcatattttt gcgcagatga agaatatcac agatcaagag gttgttcttg
     2041 aagttgggga acgtattgtc caggctgttt ttgctacttt cttaattgca gatggagatg
     2101 cagctgatgg cgttcgaact ggtggatttg gatcgacagg gcactagaat gaagattatc
     2161 tttgtacgtc atggggagcc agattaccgt gagttagagg agcgttctta tataggattt
     2221 gggatagatt tggcaccctt gtctgagatg ggacggcagc aagtccagaa attgagcaaa
     2281 aatcctttac tctcgtcagc tgaaataatc gtatcttctg cagtcacaag agctttagaa
     2341 acggcttcgt atgtggtctg tgctacgggt cttcctttaa gagtagagcc tttattacat
     2401 gaatggcagg tctataaaac aggaatagaa aactttgaaa cagctagaag actgttttta
     2461 gaaaacaagg gggagttgct tcctaatagt cctattcaat atgagacagc tacggaaatg
     2521 aagtctcggt ttctagaatg tatgtctaag tatcgagaac atcagactgt ggtagttgtt
     2581 gctcatcgaa tgctcatgcg ccagtttgtg ccaaatgaga agattgattt ttgccaagtg
     2641 attgagtgtg agttagagat atagaaagag gtttgtcatc gcaaagaaaa aagcgacatt
     2701 tgtatgtcaa aattgtgggt ataattcccc taaatatctg ggacgttgcc ccaactgtgg
     2761 gtcttggtct tcttttgtgg aagaggttga ggttgccgag gtcaagaatg cgcgtgtgtc
     2821 cttgacaggt gagaaaacca agcccatgaa actagctgag gtgacttcca tcaatgtcaa
     2881 tcgaaccaag acggagatgg aggaattcaa ccgtgtgctt ggaggcggag tggtaccagg
     2941 aagtctcgtc ctcatcggtg gggatcctgg gattgggaaa tcaactcttc tcctacaagt
     3001 ctcaacccag ttgtcccaag tggggacagt tctctatgtc agtggggagg agtctgccca
     3061 gcagattaaa ttacgtgcag agcgcttagg tgatattgat agtgagtttt atctctatgc
     3121 agagaccaat atgcagagtg ttcgtgcaga agtggagcgt atccagccag acttcttcat
     3181 tattgactct atccagacca ttatgtctcc tgagatttca ggggtgcagg ggtctgtttc
     3241 tcaggtgcgt gaagtgaccg ctgaactcat gcagttggcc aagaccaata acattgccat
     3301 ctttatcgta ggtcatgtga ccaaagaagg aaccttggct gggcctcgta tgttggagca
     3361 tatggtggat acggtgcttt actttgaagg ggagcgtcac cacacctttc gtattttgag
     3421 agcggtcaaa aatcgttttg gttccactaa tgagattggg atttttgaga tgcagtcggg
     3481 cggcttggtt gaggtactca atccgagtca agttttccta gaagagcgtt tggatggggc
     3541 gactggttcc tccatcgttg taaccatgga agggacgcgt ccgattttgg cggaggttca
     3601 ggctttagta acaccgacca tgtttggaaa tgccaagcgt actacgacag gacttgattt
     3661 taaccgtgct agcttgatta tggctgtttt ggaaaaacgg gcagggcttc tcttgcaaaa
     3721 tcaggatgcc tatctcaaat ctgctggtgg tgttaaattg gatgaacctg ccattgactt
     3781 ggctgttgca gttgctattg cttcgagcta caaagacaaa ccaactaatc ctcaggaatg
     3841 ttttgtcgga gaactgggct tgacaggaga gattcggcgc gtgaatcgta ttgagcaacg
     3901 catcaacgaa gctgctaaac tgggctttac taagatttat gtacctaaga attccttgac
     3961 aggaatcact ctgcctaagg aaattcaggt cattggcgtg acaacgattc aggaagtttt
     4021 gaaaaaggtc tttgcataat ccgtgacaaa ttctcttaaa aatgataaga taggagaaat
     4081 atttgactat caaattttca aggagggaat cgtgtcgtat tttgaacagt ttatgcaagc
     4141 caatcaggct tatgttgccc tacatgggca gttaaatctg ccacttaaac ccaaaacaag
     4201 agtagctatt gtgacctgta tggactctcg tctgcacgtt gcgcaagctc tgggcttggc
     4261 acttggggat gctcatatct tgcggaatgc aggtggtcga gtgactgaag acatgattcg
     4321 ttcgctagtt atttcccagc aacaaatggg gacaagagag attgtggtat tgcaccatac
     4381 agactgtggt gctcagacct ttgaaaatga accttttcag gagtatttaa aagaggaatt
     4441 aggtgtagat gtgtcagacc aggatttctt gcccttccaa gatatagaag agagtgtacg
     4501 cgaggatatg caactgctta tcgagtctcc cctaatacca gacgatgtca ttatctctgg
     4561 tgccatttac aatgttgata caggaagtat gacagtcgta gaattataaa tacttcattt
     4621 agaaagaaag tgtatgaaga aaagcagtat tttattgcta tgtattggtt tacagtatga
     4681 aaccatctac tatacggacg gttcgaggtc aggtgcggaa tatggactaa tgggaatttc
     4741 tatctttcta gctctctttt acatgattcc ggctctttat tttctcttcc gtattgggaa
     4801 aaatgggaat tgccaaagaa ggttttgatt ctgtctttat tgggagggat gttcctttca
     4861 ggctggttgt ctagttttgc taatacttat atccatgatt tactgggggt tcttttccca
     4921 gatagtacat ttttaaatgc ctttgaaagt gctattgtgg ctcctttggt agaagaaccc
     4981 ttgaaattat tgccacttgt ttttgttttg gctttgattc ctgtgcgaaa attaaaatct
     5041 ttgtttttac ttggaattgc ttccggtttg ggattccaaa tgattgagga tattggttat
     5101 attcgtacgg atttgccaga gggctttgac tttactattt cgcgaatttt agagcgtatc
     5161 atctcaggaa ttgcctctca ctggactttt tcaggtctag ctgtagtagg tgtttacttg
     5221 ctttacagag cctataaagg acagaaggtt ggcaagaaac agggccttat ttttctaggt
     5281 ttagccttgg gaactcactt cttgtttaac tctccttttg tggagttgga aacagagttg
     5341 cctttagcga ttccagtggt tacggctatt gctctctatg gtttttatca tgcttattgc
     5401 tttgttgaga aacacaatga gttgatgacc tagaatattt ttcaaaagaa tgatgcaagg
     5461 gtacaaatat ggtgcccttc ttttattttt gattgaaaaa tagtgcaaaa agcgctacaa
     5521 tggtagatgg aaaatcttgt gaaaggcaca agttatacat atataccgga ggaaatcatg
     5581 tctttttctg atttaaagct gtttgccctt tcttctaata aagaattggc agaacgtgtg
     5641 gcgcaggaga ttgggataga gttggggaaa tcaagtgttc gccaattttc agatggagag
     5701 attcaggtca acattgaaga atcaatccgt gggaaacacg tctttatctt acaatcaact
     5761 agttcgcctg taaatgacaa tctgcttgaa attttgatta tggtagatgc tttgaagcgt
     5821 gcgagtgcag aatctgtcaa tgttgtcatg ccttactatg ggtatgcacg tcaggataga
     5881 aaggcgagag cgcgtgagcc aatcacttca aaacttgtcg caaatatgct tgaagtagct
     5941 ggagtggatc gtttattgac catcgacttg catgctgcgc aaattcaagg attctttgat
     6001 attcctgtgg atcatttgat gggtgctcct ctgattgcag attattttga gcgtcgtggt
     6061 atggttggtt ctgactatgt ggttgtcagc ccggaccatg gaggggtgac tcgtgctcgt
     6121 aagttggcag aatttttgaa aacatctatc gctattattg ataaacgtcg tagcgttgat
     6181 aagatgaata ctagtgaagt tatgaatatc atcggtaagg ttgaaggcaa gacttgtatc
     6241 ttgattgatg atatgattga taccgctgga acgatttgtc atgcggcaga tgctcttgcg
     6301 gaagctggtg ctgttgaagt ctatgcaagc tgtacgcacc cagttctttc tggtcctgct
     6361 acggacaata tccaaaaatc agctattaag aaattggttg ttttggatac catctatctg
     6421 ccagaagagc gtttgattga taagattgag cagatttcaa tcgctcatct cctaggggat
     6481 gctatcgtac gtattcatga aaaacgacca ctttctccac ttttcgatat tgagaaaaaa
     6541 atttaatgac caagcctgag atgattctca ggttttttcg tcttttttcc gaataaatag
     6601 atagtagcgg tgaatctagt aaagctagat ttaaaactgt gatataataa aaagagaaga
     6661 aatatgactg tacgtcat
//
LOCUS       DAVBOD010000086         6522 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 640-05
            SAMEA1012484-rid20186543.denovo.087, whole genome shotgun sequence.
ACCESSION   DAVBOD010000086 DAVBOD010000000
VERSION     DAVBOD010000086.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012484
            Sequence Read Archive: ERR059358
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6522)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6522)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979948.1
            Genome Coverage       :: 595x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:03:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,266
            CDSs (total)                      :: 2,219
            Genes (coding)                    :: 2,091
            CDSs (with protein)               :: 2,091
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 71 of 128
            Pseudo Genes (incomplete)         :: 50 of 128
            Pseudo Genes (internal stop)      :: 33 of 128
            Pseudo Genes (multiple problems)  :: 22 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6522
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012484-rid20186543.denovo.087"
                     /strain="NIG 640-05"
                     /db_xref="taxon:1313"
     gene            170..370
                     /locus_tag="VQ862_002015"
     CDS             170..370
                     /locus_tag="VQ862_002015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000226586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3116300.1"
                     /translation="MVASASASSTSTQAQEQVDKSELRALSQELDQRLKALATVSDQK
                     IDATKAVLLDAQKAPEDSALTE"
     gene            412..816
                     /locus_tag="VQ862_002016"
     CDS             412..816
                     /locus_tag="VQ862_002016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000377663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3116301.1"
                     /translation="MDSLKDVKANASDSKPAQDKKDAKQGTEDSKDSDKMTETNSVPA
                     GVIVVSLLALLGVIAFWLIRRKKESEIQQLSTELIKVLGQLDAEKADKKVLAKAQNLL
                     QETLDFVKEENGSAETETKLVEELKAILDKLK"
     gene            1047..1754
                     /gene="ccdA2"
                     /locus_tag="VQ862_002017"
     CDS             1047..1754
                     /gene="ccdA2"
                     /locus_tag="VQ862_002017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004237834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     membrane protein CcdA2"
                     /protein_id="HET3116302.1"
                     /translation="METIVFLISVFLAGVLSFFSPCIFPLLPVYAGILLDDQESAKSF
                     SLFGRKVLWSGLIRTLCFIAGISLIFFILGFGAGYFGHILYANWFRYGMGAIIIILGL
                     HQMEIFHLKKLEVQKSFTFKKSDSNRYWSAFLLGITFSFGWTPCIGPVLSSVLALAAS
                     GGNGAWQGAIYTLIYTLGMALPFLVLALASGLVMPYFSKIKRHMMLLKKIGGFLIVLM
                     GILLLLGQVNVLAGIFE"
     gene            1765..2322
                     /gene="sdbB"
                     /locus_tag="VQ862_002018"
     CDS             1765..2322
                     /gene="sdbB"
                     /locus_tag="VQ862_002018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000757364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     lipoprotein SdbB"
                     /protein_id="HET3116303.1"
                     /translation="MKKVMFAGLSLLSLVVLMACGEEETKKTQAAQQPKQQTTVQQIA
                     VGKDASNFTLQSMDGKEVKLSDFKGKKVYLKFWASWCGPCKKSMPELMELAAKPDRDF
                     EILTVIAPGIQGEKTVEQFPQWFQEQGYKDIPVLYDTKATTFQAYQIRSIPTEYLIDS
                     QGKIGKIQFGAISNADAETAFKEMN"
     gene            2697..4088
                     /locus_tag="VQ862_002019"
     CDS             2697..4088
                     /locus_tag="VQ862_002019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001020339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HET3116304.1"
                     /translation="MNIFRTKNVSLDKTEMHRHLKLWDLILLGIGAMVGTGVFTITGT
                     AAATLAGPALVISIVISALCVGLSALFFAEFASRVPATGGAYSYLYAILGEFPAWLAG
                     WLTMMEFMTAISGVASGWAAYFKGLLSQYGIALPQALNGTFNPQAGTFVDLLPILVLV
                     LVTSLVLLNAKAALRFNSILVILKFSALALFVLVGIWNIKFDNWSNFAPYGFGQIYGA
                     STGIIAGASLMFFGFLGFESISMAVDEVKTPQKNIPRGIVLSLSIVTILYALVTLVLT
                     GVVHYSHLNVDDAVAFALRSVGISWAANYVSLVAILTLITVCISMTYALSRMIYSLAR
                     DGLVPAAFKELTKTSKIPKNATILTGLASAVAAGMFPLASIAAFLNICTLAYLILLAY
                     GLIRLRKEKGMPKAGEFKTPLVPLLPILSIIICLSFMLQYNMNTWIAFLVALLVGSII
                     YFTYGYKHSTIEE"
     gene            4231..5148
                     /gene="adcAII"
                     /locus_tag="VQ862_002020"
     CDS             4231..5148
                     /gene="adcAII"
                     /locus_tag="VQ862_002020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000744528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding lipoprotein AdcAII"
                     /protein_id="HET3116305.1"
                     /translation="MKKQNLFLVLLSVFLLCLGACGQKESQTGKGMKIVTSFYPIYAM
                     VKEVSGDLNDVRMIQSSSGIHSFEPSANDIAAIYDSDVFVYHSHTLESWAGSLDPNLK
                     KSKVKVLEASEGMTLERVPGLEDVEAGDGVDEKTLYDPHTWLDPEKAGEEAQIIADKL
                     SEVDSEHKETYQKNAQAFIKKAQELTKKFQPKFEKATQKTFVTQHTAFSYLAKRFGLN
                     QLGIAGISPEQEPSPRQLTEIQEFVKTYKVKTIFTESNASSKVAETLVKSTGVGLKTL
                     NPLEADPQNDKTYLENLEENMSVLAEELK"
     gene            5156..>6522
                     /gene="phtB"
                     /locus_tag="VQ862_002021"
     CDS             5156..>6522
                     /gene="phtB"
                     /locus_tag="VQ862_002021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtB"
                     /protein_id="HET3116306.1"
                     /translation="MKINKKYVAGSVAVLALSVCSYELGRYQAGQDKKESNRVAYIDG
                     DQAGQKAENLTPDEVSKREGINAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDAIISE
                     ELLMKDPNYQLKDSDIVNEIKGGYVIKVNGKYYVYLKDAAHADNIRTKEEIKRQKQEH
                     SHNHGGGSNDQAVVAARAQGRYTTDDGYIFNASDIIEDTGDAYIVPHGNHFHYIPKSD
                     LSASELAAAQAYWNGKQGSRPSSSSSHNANPAQPRLSENHNLTVTPTYHQNQGENISS
                     LLRELYAKPLSERHVESDGLIFDPAQITSRTARGVAVPHGNHYHFIPYEQMSELEKRI
                     ARIIPLRYRSNHWVPDSRPEQPSPQPTPEPSPSPQPAPSNPIDEKLVKEAVRKVGDGY
                     VFEENGVSRYIPAKDLSAETAAGIDSKLAKQESLSHKLGAKKTDLPSSDREFYNKAYD
                     LLARI"
BASE COUNT         1998 a         1201 c         1385 g         1938 t
ORIGIN      
        1 gtaaaatgaa ataagaacag gacaaatcga tcaggacagt aaaatcgaat tctaacaatg
       61 ttttagaagt ccatatgtac tattctagtt tcaatatatc ataactgttc ctagtcaacc
      121 tgcaagccct atcccagctc caagctcagc tccgactcaa gatcctagag tggtagcaag
      181 cgcttcggct agctcaacga gcacacaagc tcaagagcaa gttgacaagt ctgaacttcg
      241 tgccttgagt caagagctag accaacgctt gaaagctttg gcaacagtat ctgatcagaa
      301 aatcgatgca accaaggctg tcctcctaga tgctcaaaaa gctccggaag atagtgcctt
      361 gacagagtaa ggtctgcata ctgcagtaga gtctgtgaag gctgggctgc cttggactct
      421 ctcaaagatg tgaaagcaaa tgctagcgac agcaagcctg cacaggacaa gaaggatgca
      481 aaacaaggaa cggaagatag taaggattca gataagatga ctgaaacaaa ctcagttccg
      541 gcaggagtga ttgtggtcag tctacttgcc ctcctaggcg tgattgcctt ctggctgatt
      601 cgccgtaaga aagagtcaga aatccagcaa ttaagcacgg aattgatcaa ggttctagga
      661 cagctagatg cagaaaaagc ggataaaaaa gtccttgcca aagcccaaaa ccttctccaa
      721 gaaacccttg atttcgtgaa agaagaaaat ggctcagcag agacagaaac taaactagta
      781 gaggagctta aagcaatcct tgacaaactc aagtaaaaca tgatttatga aatgtcagac
      841 ctaaaagaca ttttcgttca caaaagcagc gatgagtaat ccttgtcgtt gctttttggc
      901 tattttgggg gataagatcc gccttgacta gcaaaagaaa agattggtcc aatagtgccc
      961 gatacgattt tgcgtagcag aaagcttaca aataaaattg aatatagtaa aataggatta
     1021 gaattattaa gaaagttggt tctttattgg aaacgatagt atttttaatc tctgtttttc
     1081 tagcaggtgt tttatccttt ttttctcctt gtatttttcc tcttctgcca gtctatgctg
     1141 ggattttatt ggatgatcaa gaaagtgcaa aaagcttttc tttgtttggg agaaaggttc
     1201 tctggtcagg cttgattcga acactttgct ttatcgctgg tatctctctc attttcttta
     1261 ttctaggctt tggtgctggt tactttggtc atattctcta tgcaaattgg tttcgatatg
     1321 gcatgggagc tattattatc attttgggtc ttcaccagat ggaaattttt catttgaaga
     1381 aattagaagt tcaaaaaagt tttaccttta aaaaatcaga ttctaatcgt tattggtcag
     1441 cttttttact tggtattacc tttagctttg gttggacacc ttgtattggt ccagttttaa
     1501 gttctgtttt agcacttgcg gcttctggag gcaatggcgc ttggcaagga gcgatttata
     1561 ctctcattta cactctgggc atggcccttc ctttcttggt attggcacta gcttcaggtc
     1621 tagtcatgcc atattttagt aaaatcaagc gtcatatgat gctactaaag aaaattggtg
     1681 gtttcctcat tgttttaatg ggaattttgt tactattagg acaagtaaat gttctagctg
     1741 gaatttttga ataaaggagg acaaatgaaa aaagtaatgt ttgctggctt aagtctcttg
     1801 tcattagttg tattgatggc ctgtggtgag gaagaaacta aaaagactca agcagcacaa
     1861 cagccaaaac aacaaacgac tgtacaacaa attgctgttg gaaaagatgc ttcaaacttc
     1921 acattgcaat ccatggatgg caaagaagtt aagttatctg attttaaggg taaaaaggtt
     1981 tacttgaagt tttgggcttc atggtgcggt ccatgcaaga aaagtatgcc agagttgatg
     2041 gaactagcgg cgaaaccaga tcgtgatttc gaaattctta ctgtcattgc accaggaatt
     2101 caaggtgaaa aaactgttga gcaattccca caatggttcc aggaacaagg atataaggat
     2161 atcccagttc tttatgatac caaagcaacc accttccaag cttatcaaat tcgaagcatt
     2221 cctacagaat atttaattga tagccaagga aagattggaa agattcaatt tggtgctatc
     2281 agtaatgcgg atgcagaaac agcatttaaa gaaatgaact agaatcgata aaatctgatt
     2341 acaagatgta gtcagatttt ggtaacttct aaaactaact tccagtttcc cacaacctag
     2401 cttttagtat gagaaaaacg cgtgacatca gtggaaatcc gtcttagact aacttccact
     2461 ggttttcttt ttcttgatat ataagggttc aaaagcgaaa agactcagaa aaaagtgcac
     2521 gacaaatagc cctaaaacag agtcgtttta gagtaacttc cagttttggg agagagatgg
     2581 aagttacttt gagaagttac ggtagtcaga tttttttaga aaaacatttt ataaatattc
     2641 acatatctcc tatatttatg gtaaaataga atcatcagtt tattttggag tcaaagatga
     2701 atatatttag aacaaagaat gttagtttag ataaaacaga gatgcatagg catttgaagt
     2761 tatgggattt gattttgctg ggtattggag ccatggtagg gacaggtgtc tttacaatca
     2821 caggtactgc agctgctaca cttgctggtc cagcactagt gatttcaatc gttatttctg
     2881 ccttgtgtgt gggattatca gccctctttt ttgcagaatt tgcctcgcga gtacccgcta
     2941 caggaggtgc ctatagttac ctctatgcta tcttaggaga attccctgcc tggttggctg
     3001 gttggttaac catgatggag ttcatgacag ccatatcagg cgtagcttcg ggttgggcag
     3061 cttattttaa aggcttgctc tctcaatacg ggatagccct tcctcaggct ttaaatggta
     3121 cctttaatcc tcaagcaggg acatttgttg atttattgcc tattcttgtc ttggtcttgg
     3181 tgacttcgct tgttttacta aatgccaagg cagccttacg ctttaattcg attctagtta
     3241 ttttgaaatt ttccgcttta gctctctttg ttttagtagg aatttggaat attaagtttg
     3301 ataattggag caattttgct ccttacggtt ttggacaaat ctatggagct agtactggta
     3361 ttatagctgg tgcgtccttg atgttcttcg gttttttggg atttgaatcc atctctatgg
     3421 ctgtagatga agtcaagact cctcaaaaaa atattcctag agggattgtc ttatcgcttt
     3481 ctatcgtaac cattctctat gccttggtga cccttgtttt gactggtgtg gttcactata
     3541 gtcatttaaa tgtcgatgat gccgttgcct ttgcccttcg tagtgttggg attagttggg
     3601 cagccaacta tgtgtcatta gtggctatct tgaccttgat tacagtttgt atttcgatga
     3661 cctatgccct atcgcgtatg atttacagtt tagcacgtga tggcttagtg cctgctgcct
     3721 ttaaggaact gacgaagact agcaagatac caaagaatgc tactatcttg acaggtctag
     3781 cttcagcagt agcagcagga atgttcccgc tagccagtat tgcagccttt ttaaatattt
     3841 gtaccttagc ctacttgatc ctgctggctt atggtctgat tcgcttacgg aaagaaaaag
     3901 gaatgcccaa agctggggaa tttaaaacac cattggtacc tctgttacca attttatcga
     3961 tcatcatttg tttatccttc atgttacagt ataatatgaa tacctggatt gctttcctag
     4021 ttgcgttgtt agtaggaagt attatttact tcacttatgg ctataagcat tctaccatag
     4081 aagaataaag tgaaagtcta ttgagttgtt gacactcagt agatttttat atgtgaaaga
     4141 aatttcaaat tttttctaaa aatatcttga cagattaaat tttcaggagt agaatattta
     4201 ctagttaatt aaatggttaa ggagttgttc atgaagaaac aaaatttatt tttagtcctg
     4261 ttaagtgtct ttcttttgtg cttgggggct tgtggtcaaa aggaaagtca gacaggaaag
     4321 gggatgaaaa ttgtgaccag tttttatcct atctacgcta tggttaagga agtatctggt
     4381 gacttgaatg atgttcggat gattcagtca agtagtggta ttcactcctt tgaaccttcg
     4441 gcaaatgata tcgcagccat ctatgattca gatgtctttg tttaccattc tcatacactc
     4501 gaatcttggg caggaagtct ggatccaaat ctaaaaaaat ccaaagtgaa ggtcttagag
     4561 gcttctgagg gaatgacctt ggaacgtgtc cctggactag aggatgtgga agcaggggat
     4621 ggagttgatg aaaaaacgct ctatgaccct cacacatggc tagatcctga aaaagctgga
     4681 gaagaagccc aaattatcgc tgataaactt tcagaggtgg atagtgagca taaagagact
     4741 tatcagaaaa atgcgcaagc ctttatcaaa aaagctcagg aattgactaa gaaattccaa
     4801 ccaaaatttg aaaaagcgac tcagaaaaca tttgtaacac aacatacagc cttttcttat
     4861 ctagcgaaga gatttgggct taatcaactt ggtattgcag gcatctctcc tgaacaagaa
     4921 ccaagtccac gacaattaac agaaattcag gaatttgtta aaacctataa ggttaaaacg
     4981 atttttacag aaagtaatgc ttcttcaaaa gtagctgaaa ctcttgtcaa atcaacaggt
     5041 gtgggtctta aaactctgaa tcctttagag gcagacccac aaaatgacaa gacctattta
     5101 gaaaatctgg aagaaaatat gagtgttcta gcagaagaat taaagtgagg aaagaatgaa
     5161 aatcaataaa aaatatgtag caggttcagt ggcagttctt gccctaagtg tttgttccta
     5221 tgaacttggg cgttaccaag ctggtcagga taagaaagag tctaatcgag ttgcttatat
     5281 agatggtgat caggctggtc aaaaggcaga aaatttgaca ccagatgaag tcagtaagag
     5341 ggaggggatc aacgccgaac aaatcgtcat caagattacg gatcaaggtt atgtgacctc
     5401 tcatggagac cattatcatt actataatgg caaggtccct tatgatgcca tcatcagtga
     5461 agagctcctc atgaaagatc cgaattatca gttgaaggat tcagacattg tcaatgaaat
     5521 caagggtggt tatgtcatta aggtaaacgg taaatactat gtttacctta aggatgcagc
     5581 tcatgcggat aatattcgga caaaagaaga gattaaacgt cagaagcagg aacacagtca
     5641 taatcacggg ggtggttcta acgatcaagc agtagttgca gccagagccc aaggacgcta
     5701 caccacagat gatgggtata tcttcaatgc atctgatatc attgaggaca cgggtgatgc
     5761 ttatattgtc cctcacggca atcacttcca ctatattcct aagagtgatt tgtctgccag
     5821 tgaattagct gctgcccaag cctattggaa tgggaagcag ggatctcgtc cttcttcaag
     5881 ttctagtcat aatgcaaatc cagctcaacc aagattgtca gagaaccaca atctgactgt
     5941 cactccaact tatcatcaaa atcaagggga aaacatttca agccttttac gtgaattgta
     6001 tgctaaaccc ttatcagaac gccatgtgga atctgatggc cttattttcg acccagcgca
     6061 aatcacaagt cgaaccgcca gaggtgtagc tgtccctcat ggtaaccatt accactttat
     6121 cccttatgaa caaatgtctg aattggaaaa acgaattgct cgtattattc cccttcgtta
     6181 tcgttcaaac cattgggtac cagattcaag accagaacaa ccaagtccac aaccgactcc
     6241 agaacctagt ccaagtccgc aaccagctcc aagcaatcca attgatgaga aattggtcaa
     6301 agaagctgtt cgaaaagtag gcgatggtta tgtctttgag gagaatggag tttctcgtta
     6361 tatcccagcc aaggatcttt cagcagaaac agcagcaggc attgatagca aactggccaa
     6421 gcaggaaagt ttatctcata agctaggagc taagaaaacc gacctcccat ctagtgatag
     6481 agaattttac aataaggctt atgacttact agcaagaatt ca
//
LOCUS       DAVBOD010000087         6297 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 640-05
            SAMEA1012484-rid20186543.denovo.088, whole genome shotgun sequence.
ACCESSION   DAVBOD010000087 DAVBOD010000000
VERSION     DAVBOD010000087.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012484
            Sequence Read Archive: ERR059358
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6297)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6297)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979948.1
            Genome Coverage       :: 595x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:03:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,266
            CDSs (total)                      :: 2,219
            Genes (coding)                    :: 2,091
            CDSs (with protein)               :: 2,091
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 71 of 128
            Pseudo Genes (incomplete)         :: 50 of 128
            Pseudo Genes (internal stop)      :: 33 of 128
            Pseudo Genes (multiple problems)  :: 22 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6297
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012484-rid20186543.denovo.088"
                     /strain="NIG 640-05"
                     /db_xref="taxon:1313"
     gene            complement(58..384)
                     /locus_tag="VQ862_002022"
     CDS             complement(58..384)
                     /locus_tag="VQ862_002022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001822577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HET3116307.1"
                     /translation="MVEYISRKYFLTEEEFQAEKICNQSLVELFQKKYSWHSLNDFGS
                     STYDKNYASIFYEYWRSFLTVDKLVENLGSVQAVLDSYHLWANTEKTFPLLDWFVQQK
                     LIEKEI"
     gene            complement(351..635)
                     /locus_tag="VQ862_002023"
     CDS             complement(351..635)
                     /locus_tag="VQ862_002023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HET3116308.1"
                     /translation="MDNLYLVKDDSQLATFRDFVVRNTEKLKDYQSFLKNELAVCDLP
                     QAVIWSDFNAATQIIRESAVPAYTNNRRMVMTLISGSKRGWLNILVASIS"
     gene            complement(908..1750)
                     /locus_tag="VQ862_002024"
     CDS             complement(908..1750)
                     /locus_tag="VQ862_002024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HET3116309.1"
                     /translation="MNTYQLNNGVEIPVLGFGTFKAKDGEEAYRAVLEALKAGYRHID
                     TAAIYQNEESVGQAIKDSGVPREEMFVTTKLWNSQQTYEQTRQALEKSIEKLGLDYLD
                     LYLIHWPNPKPLRENDAWKTRNAEVWRAMEDLYQEGKIRAIGVSNFLPHHLDALLETA
                     TIVPAVNQVRLAPGVYQEQVVAYCREKGILLEAWGPFGQGELFDSKQVQEIAANHGKS
                     IAQIALVWSLAEGFLPLPKSVTTSRIQANLDCFGIELSHEERETLKTIAVQSGAPRVD
                     DVDF"
     gene            complement(1864..3255)
                     /locus_tag="VQ862_002025"
     CDS             complement(1864..3255)
                     /locus_tag="VQ862_002025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013193417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HET3116310.1"
                     /translation="MNKSRLGRGRHGKTRHVLLALIGILAISICLLGGFIAFKIYQQK
                     SFEQKIESLKKEKDDQLSEGNQKEHFRQGQAEVIAYYPLQGEKVISSVRELINQDVKD
                     KLESKDNLVFYYTEQEESGLKGVVNRNVTKQIYDLVAFKIEETEKTSLGKVHLTEDGQ
                     PFTLDQLFSDASKAKEQLIKELTSFIEDKKIDQDQSEQIVKNFSDQDLSAWNFDYKDS
                     QIILYPSPVVENLEEIALPVSAFFDVIQSSYLLEKDAALYQSYFDKKHQKVVALTFDD
                     GPNPATTPQVLETLAKYDIKATFFVLGKNVSGNEDLVKRIKSEGHVVGNHSWSHPILS
                     QLSLDEAKKQITDTEDVLTKVLGSSSKLMRPPYGAITDDIRNSLDLSFIMWDVDSLDW
                     KSKNEASILTEIQHQVANGSIVLMHDIHSPTVNALPRVIEYLKNQGYTFVTIPEMLNT
                     RLKAHELYYSRDE"
     gene            complement(3490..3867)
                     /locus_tag="VQ862_002026"
     CDS             complement(3490..3867)
                     /locus_tag="VQ862_002026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001833802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family transposase"
                     /protein_id="HET3116311.1"
                     /translation="MICQFIRDMLDLPAKNVTILEGSNIHVLPSMPYSAQDFYTSIDV
                     LAELDNGIQVIIEIQVHHQNFFINRLWAYLCSQVNQNLEKIRQREGDTHQSYKQIALV
                     YAIAIVDSNYFSDDLAFHSFIVK"
     gene            4082..5059
                     /locus_tag="VQ862_002027"
     CDS             4082..5059
                     /locus_tag="VQ862_002027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HET3116312.1"
                     /translation="MLKLGVIGTGAISHHFIEAAHTSGEYQLVAIYSRKLETAATFAS
                     RYQNIQLFDQLEVFFKSSFDLVYIASPNSLHFAQAKAALSAGKHVILEKPAVTQPQEW
                     FDLIQTAEKNNCFIFEAARNYHEKAFTTIKNFLTDKQVLGADFNYAKYSSKMPDLLAG
                     QTPNVFSDRFAGGALMDLGIYPLYAAVRLFEKANDATYHAQQLDNSIDLNGDGILFYP
                     DYQVHIKAGKNITSNLPCEIYTTDGTLTLNTIEHIRSAIFTDHQGNQVQLPIQQAPHT
                     MTEEVAAFAHMIQQPDLNLYKTWLYDAGSVHELLYTMRQTAGIRFEAEK"
     gene            5056..6138
                     /locus_tag="VQ862_002028"
     CDS             5056..6138
                     /locus_tag="VQ862_002028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HET3116313.1"
                     /translation="MKTKLPTEWQELSDQLGFQEFTPIQTQLFEPLLAGENLLGVSQT
                     GTGKTLAYLLPSLLRLQKKKAQQLLILAPNTELAGQIFDVCKTWAEAIGLTAQLFLSG
                     SSQKRQIERLKKGPEILIGTPGRIFELIKLKKIKMMNVETIILDEFDQLLDDSQIHFV
                     EKITHYAPRDHQLVYMSATTKFDQEKIVPNTRTIDLSDQKLDNIQHFYMQVDQRHRVD
                     MLRKLAHVEDFRGLVFFNSLSDLGNAEEKLQYRDILTVSLASDVNVKFRKIILEKFKD
                     NQLTLLLATDLLARGIDIDSLECVVNFDIPRDSETYTHRAGRTGRIGKEGYVITLVTH
                     PEEIKKLKKFASIREIVLKNQELYIK"
BASE COUNT         1895 a         1389 c         1058 g         1955 t
ORIGIN      
        1 tctgccactg atgcagtgaa atgtcaattt cttagacatt gtttactcct ttagttttta
       61 tatttctttt tcaattaatt tctgctgaac aaaccaatct aacaagggaa aagttttttc
      121 tgtatttgcc cataaatgat aagaatctaa gaccgcttgt acactaccta aattttctac
      181 caacttatct actgtcaaaa agctgcgcca gtattcataa aaaatacttg catagttctt
      241 atcataagtc gaagaaccaa aatcattcaa tgaatgccaa ctatacttct tctgaaaaag
      301 ttctacgaga gattgattac aaattttttc cgcttgaaat tcctcttctg tcaagaaata
      361 cttgcgacta atatattcaa ccatcccctc ttcgaaccag atataagagt cataaccatt
      421 cgtctattat ttgtataggc tggaacagcg ctttccctaa taatctgtgt agcagcatta
      481 aaatctgacc aaataacggc ttgcggtaaa tcacagactg caagttcatt ctttaaaaaa
      541 gattgataat ctttcaactt ttcagtattt cttactacaa aatcacgaaa tgtagctagt
      601 tgactatcgt cttttacaag ataaaggttg tccacggctc tcctttcttt cacacaatag
      661 actgaataag caaaagaacc acatctgaca atcctaggtt gatttaacct aggggcgtca
      721 gaaacgcggt tccaccctaa tttattactt cattgttttt gaaaatacta cagaaagcgc
      781 cagctcatta ttttgcccta cttggctccc actgtcccaa gctcgcttga agaacgccat
      841 aagactttct ttcctgctga ctattatatc aaaaattaga ataatgtaca attcttttta
      901 tgattttcta gaaatccaca tcatcaactc gtggagcacc cgattgaaca gcaatcgttt
      961 ttaaggtttc tctctcctca tgactcagtt caattccaaa gcaatcaaga ttagcttgaa
     1021 tacgagaggt tgtgacagat tttggaagtg gtaaaaatcc ttctgccaag ctccagacca
     1081 aggctatctg agcaatcgat tttccgtgat ttgctgcgat ttcttgcact tgcttgctat
     1141 caaatagttc tccctgacca aaaggccccc aagcttccaa taaaattccc ttttcacgac
     1201 agtaagctac gacttgttct tgatacacac ctggcgccaa gcgaacttga ttgaccgcag
     1261 gaacgatagt tgcagtttca agcaaggcat ccaaatgatg gggaagaaaa ttgctaacgc
     1321 cgatagcacg gattttccct tcttgataga ggtcttccat cgctctccaa acttccgcat
     1381 tgcgagtttt ccatgcgtca ttttctctga gcggttttgg gttcggccaa tgaatcaaat
     1441 acaaatccaa ataatccaag cccagttttt ctatagattt ttccaaagct tgacgagttt
     1501 gctcataggt ttgctgacta ttccaaagct tggtagttac gaacatttct tcacgtggaa
     1561 ctccgctatc tttgattgct tgaccaacac tttcttcatt ctgataaatc gccgccgtat
     1621 caatatgacg ataaccagcc ttcaaggctt ctaacactgc acgataggct tcttctccat
     1681 ccttagcctt aaaagttcca aatcccaata ctggaatttc tactccatta tttaattgat
     1741 aggtattcat atgcttctcc ttctatttta ttcatcaatt atagcataaa acatttttta
     1801 agtagtacta tattctgtaa aaaataagtc tgtcaaatat ctaacagacc tattttttct
     1861 tgcttattca tcacgactat agtacagctc atgagctttt aggcgagtat tgagcatctc
     1921 tggtatggtc acaaaggtat aaccttgatt tttcaaatac tcaatgaccc ttggcaaggc
     1981 attgactgtc ggactgtgaa tatcatgcat caaaacgata gagccgttag ctacttgatg
     2041 ctgaatttct gtcaaaatag atgcttcatt tttactcttc cagtccagac tatccacatc
     2101 ccacatgata aagctcaaat ccaagctatt gcgaatatca tctgtaatag caccataagg
     2161 tggacgcatg agtttagaac tagaacccag cactttagtt agcacatcct cagtatcagt
     2221 aatctgcttt ttagcttcat caagagagag ttgcgagaga atcggatggc tccaactatg
     2281 gtttccaaca acatgacctt cagattttat cctcttcacc aagtcctcat tcccagaaac
     2341 atttttccca agcacaaaga aagtcgcttt aatatcatat ttagctaggg tctctaatac
     2401 ctgcggggtc gttgctggat ttggaccatc atcaaaggtt agagcgacaa ctttttgatg
     2461 tttcttatca aagtaagatt ggtacaaggc cgcatctttt tcgagtaagt acgaagattg
     2521 gataacatca aagaaagcag atactggcaa ggctatctct tctaaatttt caaccacagg
     2581 acttggataa aggataatct gactatcctt gtaatcaaaa ttccatgcag acaagtcttg
     2641 gtcagagaag ttttttacaa tctgctcact ctggtcttga tctatttttt tatcctctat
     2701 gaaggaggtc aactctttta tcagctgttc cttagcctta ctagcatctg aaaacagttg
     2761 gtcaagtgta aaaggttgcc catcttctgt taagtgaacc tttcctagac tggtcttttc
     2821 agtctcttca atcttaaaag caactaaatc atagatttgt ttggtcacat tacgattaac
     2881 gactcccttt aaacctgact cttcttgctc tgtatagtag aaaacaagat tgtccttact
     2941 ttctagcttg tccttaacat cttgatttat cagctcccta acagaggaaa tcactttctc
     3001 cccttggaga ggataatagg caatcacttc ggcttgcccc tgacgaaaat gctccttctg
     3061 atttccctca ctcaattgat catctttctc ttttttgagc gattcaatct tttgctcaaa
     3121 acttttttgc tggtagatct taaaagcaat aaatccgcct aataggcaaa tagaaattgc
     3181 taaaatacca atcaaagcca ataatacatg tctcgttttc ccgtgtctgc cacgtcctag
     3241 tctactttta ttcatattta tatcataaca aatttgagca ataatttcaa tgatacaatt
     3301 tggcaatcca caattcctct agcaagccaa agcatcttac atcaactcca acatccgtat
     3361 ctgtagagat tatgtagttt tctatctatg gaatttctag tagattgaag ctagaatagt
     3421 agacctatac ttctaaaaca ttgttagaaa tcgatttgac tgtcctgatc gatttgtcct
     3481 gttctcattt cattttacta taaaactatg aaaagctagg tcatctgaga agtaattact
     3541 atcgacaatt gcgatagcgt atactagtgc gatttgtttg tagctctggt gggtatcacc
     3601 ttcacgttgg cgaatttttt ctaggttttg attaacctga ctgcacagat aagcccatag
     3661 gcgattgatg aaaaaattct gatgatgaac ctgaatttcg atgataactt ggattccatt
     3721 atctaactcc gccaagacgt ctatactagt atagaaatct tgcgctgagt agggcatgga
     3781 aggcaagacg tgaatgttac ttccctccaa aatcgtcaca ttttttgctg gcaagtccag
     3841 catatcgcgg ataaattgac aaatcattag ttgggctgat acctggatgt ctgagaatcc
     3901 tccttttcct ccttctatta tagcacattt ttaaatctag gtttgctaga ttctatgctt
     3961 ctatctattt attcggaaaa gaaagctaat agcttatttg aaattttctc ctctctgttg
     4021 gatagtcccg tctatctatg ttataatgaa agaaggattt aaaatcggaa aaggagtatt
     4081 tatgctaaaa ttaggtgtca tcggaactgg cgctatcagc catcatttca tagaagcagc
     4141 ccataccagt ggagaatacc aactggtcgc aatctattct agaaaactag aaactgcagc
     4201 aacctttgct tctcgctatc agaatatcca actattcgat caattagaag tcttcttcaa
     4261 atcttctttt gatttagtct atatcgccag tccaaactcc ttacattttg ctcaggcaaa
     4321 agctgccttg tctgctggta aacatgttat tctcgaaaag ccagctgtca ctcaaccaca
     4381 agaatggttt gatttgattc aaacagctga aaaaaataac tgttttatct ttgaagcagc
     4441 tcgtaattac cacgagaaag cctttactac tatcaaaaac tttttaacag ataagcaagt
     4501 gttaggagca gatttcaact atgccaaata ctcttccaag atgcctgact tgttggctgg
     4561 acaaacacca aatgtctttt cagaccgttt tgctggtgga gccctcatgg atttggggat
     4621 ttatcccctc tatgctgctg ttcgtctttt tgaaaaagct aatgacgcga cttaccatgc
     4681 tcaacagctt gacaatagca ttgacctaaa tggagatggt atcctcttct acccagacta
     4741 tcaagttcac atcaaggctg gaaaaaacat cacttccaat cttccttgcg agatttatac
     4801 aacagatgga accttgactc tcaacacgat tgagcatatt cgctcagcta tttttaccga
     4861 ccaccaagga aatcaagtcc agcttcctat ccaacaggct cctcatacga tgactgagga
     4921 agtcgctgca tttgcacaca tgatccagca accagatctg aatctctaca aaacttggct
     4981 gtatgatgca ggctctgttc atgagctact atataccatg cgccagactg ctggcattag
     5041 atttgaggca gaaaaatgaa aaccaaacta ccgactgaat ggcaagaact gagtgaccaa
     5101 ctcggtttcc aagaattcac ccccattcaa actcaactat ttgagcccct tcttgctgga
     5161 gaaaacctcc taggagtgag ccaaaccgga actggtaaga ccctagcgta tctcctacca
     5221 agtcttctca gactacaaaa gaaaaaagcc caacaactct tgattctagc accaaacacg
     5281 gaacttgctg gacagatttt tgatgtatgt aaaacgtggg cagaagctat cggattgact
     5341 gctcaactct tcctttcagg ttcaagtcag aaacgacaaa ttgaacgtct taaaaagggg
     5401 ccagaaattc tgattggaac tcctggccgt atctttgaac tcattaaact taaaaaaatc
     5461 aagatgatga atgtggaaac catcatcctg gatgaatttg accaattact agatgattct
     5521 cagattcact ttgtagaaaa aatcactcac tacgcacctc gtgaccacca actggtctac
     5581 atgagtgcca cgaccaagtt tgaccaagaa aagattgtgc cgaatacacg cactattgat
     5641 ctctctgacc aaaaattgga caatatccag catttctaca tgcaggtaga ccaacgtcat
     5701 cgagtggata tgctacgaaa actggctcat gtagaggatt tccgtggtct agtcttcttc
     5761 aatagcctgt cagaccttgg gaatgccgag gaaaaactac agtatcgtga tatattgact
     5821 gtttccctcg ctagtgatgt taatgttaaa tttagaaaaa tcatcttaga aaagtttaaa
     5881 gataaccaac taaccctgct tcttgcaact gaccttttgg ctcgtggaat tgatatcgat
     5941 agcctagaat gtgtcgtaaa ctttgatatt cctagagata gcgaaaccta cacacaccgt
     6001 gctggtcgta ctggccgtat aggcaaggaa ggatatgtta ttactctcgt cactcatcca
     6061 gaagaaatca aaaaacttaa aaagtttgca agtatccgag aaattgtcct aaaaaaccaa
     6121 gaactctata tcaaataaag ccccattgct ctatacacat ccagtgtatg gagctttttt
     6181 ataagcaatt caattttata ctcatctgct ttcaaaaagc attctattcc atctccgatt
     6241 aacgatggac tttatcacct ccttctccag tccttgtatg acatcttgga gttgatt
//
LOCUS       DAVBOD010000088         6238 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 640-05
            SAMEA1012484-rid20186543.denovo.089, whole genome shotgun sequence.
ACCESSION   DAVBOD010000088 DAVBOD010000000
VERSION     DAVBOD010000088.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012484
            Sequence Read Archive: ERR059358
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6238)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6238)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979948.1
            Genome Coverage       :: 595x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:03:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,266
            CDSs (total)                      :: 2,219
            Genes (coding)                    :: 2,091
            CDSs (with protein)               :: 2,091
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 71 of 128
            Pseudo Genes (incomplete)         :: 50 of 128
            Pseudo Genes (internal stop)      :: 33 of 128
            Pseudo Genes (multiple problems)  :: 22 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6238
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012484-rid20186543.denovo.089"
                     /strain="NIG 640-05"
                     /db_xref="taxon:1313"
     gene            451..636
                     /locus_tag="VQ862_002029"
                     /pseudo
     CDS             451..636
                     /locus_tag="VQ862_002029"
                     /inference="COORDINATES: protein motif:HMM:NF024172.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            1248..1532
                     /locus_tag="VQ862_002030"
     CDS             1248..1532
                     /locus_tag="VQ862_002030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002923859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3116314.1"
                     /translation="MDWYDYMIQASKQSQFNASHWFRYLRKVIFEDYSYLTNQDVEKL
                     LDSKELTRFQKISLKYAFQEHTPTHKYVISLNKPAKLTNVQKLMEKYKHG"
     gene            1525..1763
                     /locus_tag="VQ862_002031"
                     /pseudo
     CDS             1525..1763
                     /locus_tag="VQ862_002031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397100.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            1859..2077
                     /locus_tag="VQ862_002032"
     CDS             1859..2077
                     /locus_tag="VQ862_002032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001849851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3116315.1"
                     /translation="MMSIREQDLQDIGAIIKYKNFHSPFDTFKYLKDMGFDTIDLSVL
                     LEGFSYAYGMDWLEKFFKENQDKLREFY"
     gene            complement(2449..4773)
                     /gene="pflB"
                     /locus_tag="VQ862_002033"
     CDS             complement(2449..4773)
                     /gene="pflB"
                     /locus_tag="VQ862_002033"
                     /EC_number="2.3.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate C-acetyltransferase"
                     /protein_id="HET3116316.1"
                     /translation="MVVKTVVEAQDIFDKAWEGFKGVDWKEKASVSRFVQANYTPYDG
                     DESFLAGPTERSLHIKKIVEETKAHYEETRFPMDTRPTSIADIPAGFIDKENEVIFGI
                     QNDELFKLNFMPKGGIRMAETTLKENGYEPDPAVHEIFTKYVTTVNDGIFRAYTSNIR
                     RARHAHTVTGLPDAYSRGRIIGVYARLALYGADYLMQEKVNDWNAIKEIDEETIRLRE
                     EVNLQYQALQQVVRLGDLYGVDVRKPAMNVKEAIQWVNIAFMAVCRVINGAATSLGRV
                     PIVLDIFAERDLARGTFTESEIQEFVDDFVMKLRTVKFARTKAYDQLYSGDPTFITTS
                     MAGMGNDGRHRVTKMDYRFLNTLDNIGNSPEPNLTVLWTDKLPYNFRRYCMHMSHKHS
                     SIQYEGVTTMAKDGYGEMSCISCCVSPLDPENEEQRHNIQYFGARVNVLKALLTGLNG
                     GYDDVHKDYKVFDIDPIRDEVLEFESVKANFEKSLDWLTDTYVDALNIIHYMTDRYNY
                     EAVQMAFLPTKQRANMGFGICGFANTVDTLSAIKYATVKPIRDEDGYIYDYETIGDYP
                     RWGEDDPRSNELAEWLIEAYTTRLRSHKLYKDAEATVSLLTITSNVAYSKQTGNSPVH
                     KGVYLNEDGSVNLSKLEFFSPGANPSNKAKGGWLQNLNSLSSLDFSYAADGISLTTQV
                     SPRALGKTRDEQVDNLVTILDGYFENGGQHVNLNVMDLNDVYEKIMSGEDVIVRISGY
                     CVNTKYLTPEQKTELTQRVFHEVLSMDDALDALS"
     gene            5168..6229
                     /gene="dinB"
                     /locus_tag="VQ862_002034"
     CDS             5168..6229
                     /gene="dinB"
                     /locus_tag="VQ862_002034"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000904550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase IV"
                     /protein_id="HET3116317.1"
                     /translation="MLIFPLLNDLSRKIIHIDMDAFFAAVEIKDNPKLRGKPVIIGSD
                     PRQTGGRGVVSTCSYEARAFGVHSAMSSKEAYERCPQAVFISGNYEKYKAVGLQIRAI
                     FKRYTDLIEPMSIDEAYLDVTENKLGIKSAVKIARLIQKDIWQELHLTASAGISYNKF
                     LAKMASDYQKPHGLTVILPEQAENFLKQMDISKFHGVGKKTVERLHQMGVFTGADLLE
                     VPEVTLIDRFGRLGYDLYRKARGIHNSPVKSNRIRKSIGKEKTYGKILRAEEDIKKEL
                     TLLSEKVALNLHQQEKAGKIVILKIRYEDFSTLTKRKSLAQKTQDASQISQIALQLYE
                     ELSEKERGVRLLGITLTGF"
BASE COUNT         2018 a         1146 c         1182 g         1892 t
ORIGIN      
        1 gaactgacga agtcagtaac atctatacgg taaggcgacg ctgacgtggt ttgaagagat
       61 tttcgaaaag tattagttaa atcttgttta atatctctac accatactat tttacatata
      121 ttatttagcg ccacatagta ctgaactctc tccaaaaacg gttatgcctc tttgaatagg
      181 gcgttatcac aagaaaagca tctccacgtt tcaacttcat atggctcaaa aacaatcaat
      241 tgatgctaaa acctgtacct agatgtttcg gttcataaaa ccatgaaact gtaaaagtgg
      301 atgaaattga tagcgatagt caaatcaaga ggcatcataa ctctaaaaag tcacaatata
      361 taagttcatc ctcggaaaaa tatcattcta attgttgaaa tggatatata aacaggggta
      421 ttaacattaa atgctcatga aacaacgaat acaggtatca aaactatgac aaaacaagtc
      481 cctaaattta ctaaagacac tgctcaactt tacacctgta aatggttgtt gtataataaa
      541 gttacaaaga tgtacgacca cactgttgta aatcatagtg ttcgcgaata tattactgat
      601 agcatttcta caaatacaat tgaagaggct ggataggctt taaacgaaat atgtcagtgt
      661 tttggcattc ctagccttaa tatcatttaa agaattgtat agataaaatt ttttccaata
      721 cagacactcg taacaactgc ttcatttttc taccaacata tttaggaaca ggataagata
      781 caagaggatt aatccataaa tcagttctat accaatctaa gacaaataag ctaaaaaaac
      841 gattgataat aagcaaatag attccaaatt ttctctatct gctcatttta ataaacaata
      901 ctagtgtaac tatccttcca gtcagaaact tgtcaaatca caccgaaaac tcttctaaaa
      961 tttatctcgt taggcaatca agcaaaaact cgacgatagt acaaacatta tcatacagaa
     1021 ttgactgcct aaattatata ctttagtaag gttttcggat aagaaaaaag gttcatttta
     1081 catttctaaa cattcttttc taagatgaaa aacagaattt ttcgattgtg atttaaagca
     1141 acaagaagat tttcagtatc atcctataga tacgagctaa ttaagaaaaa ctacattttt
     1201 gaatataaac tacaataata taaactaaat tttataggag gaagacaatg gattggtacg
     1261 attatatgat acaggcatcc aaacaatcac aattcaacgc aagccattgg tttcgctatt
     1321 tgcgaaaagt tatttttgaa gactattctt atttaacaaa ccaagatgta gaaaagttgc
     1381 tagactccaa agaactaacc cgttttcaaa aaattagctt gaagtatgcc tttcaagagc
     1441 atactccaac tcataaatat gtgatttcat taaataaacc tgctaagtta accaatgttc
     1501 aaaaattgat ggagaaatac aaacatggat aaaatgaaac cggtcttcca agccctaaat
     1561 aagaaattaa ttcaggaaaa tctgacttta acaattatgg ttatgtctta gaatatcatg
     1621 gtttacgtgc cacacaagat gttgatgctt tttatgacca aaatcagaaa atcaatgaaa
     1681 ttattgctcg tgtaggaaaa cagtttaatc ttaacatcca cgaagagtta tggctcaaca
     1741 atcatgttgc aaagcaaata tgaacaaaca acctccctta agtttatgcg aatccttgta
     1801 ctcatttgag aatctgaccg ttttagtagt ccctattgag tatgtgttag gaatgaagat
     1861 gatgagtatc agagagcagg atttgcaaga tattggtgca attattaaat acaaaaactt
     1921 tcattcacca ttcgatacct ttaaatattt aaaagacatg ggatttgata ctattgacct
     1981 ctctgttcta ttagaaggtt ttagttatgc ttatggtatg gattggttag aaaaattttt
     2041 taaagaaaat caagataaac ttcgcgaatt ttattaacag tatcaaacaa gatgattgtc
     2101 aattagccag tcgtcttatt tttatgatga aatgaaatga aataaaatcg gaacaaatca
     2161 cttagagaat tccagtcaat ttctagcact gtttgagccg tttcagcgga ctatagtaaa
     2221 atgaaataag aataggacaa atcgatcagg acagtcaaat cgatttctaa gaatgtttta
     2281 gaagtaaagg tgtactattc tagtttcaat ctattatatt tcagattcgg tccactgttc
     2341 cttcccaaaa acattgcata ttgcgccgaa ggaattgctc atactatccc aagcacaaaa
     2401 ccctcagtcg tttgaccgag ggttcctttt tattattcaa gaacttgatt agctcaatgc
     2461 atccaaggcg tcatccattg aaagaacttc gtggaagaca cgttgtgtca attcagtttt
     2521 ttgttctgga gtgaggtatt tagtgtttac acagtatcca gagatacgta cgataacgtc
     2581 ttcgcctgac atgatttttt cgtaaacatc gttcaagtcc ataacgttca agttaacgtg
     2641 ttgtccaccg ttttcgaagt aaccatcaag gattgttacc aagttatcaa cttgttcatc
     2701 acgagtctta ccaagagcgc gaggtgatac ttgtgtagtc aatgagatac cgtcagctgc
     2761 ataactaaag tcaaggctag aaagtgagtt caagttttgc aaccaaccac ctttagcttt
     2821 gttagatggg ttagcacctg gtgagaagaa ttcaagttta gacaagttca cagaaccatc
     2881 ttcgttgagg tatacacctt tgtgaactgg tgagttacca gtttgtttag agtaagcaac
     2941 gttagatgtg attgtcaaaa gtgatactgt agcttctgcg tctttgtata gtttgtggct
     3001 acgtagacga gttgtgtaag cttcgatcaa ccattctgcc aattcgtttg aacgtgggtc
     3061 atcttcaccc cagcgtgggt agtcaccgat tgtttcgtaa tcgtagatgt agccatcttc
     3121 gtcacggatt ggtttaactg tagcgtattt gatagctgac aatgtatcaa cagtgttagc
     3181 aaatccacag ataccgaatc ccatgttggc acgttgttta gttggcaaga aggccatttg
     3241 aacagcttcg tagttgtacc tatcagtcat gtagtggatg atgttcaagg catctacgta
     3301 agtgtcagtc aaccagtcaa gagatttttc aaagttcgct ttaactgatt cgaattcaag
     3361 aacttcgtca cgaataggat cgatgtcaaa tactttgtag tctttgtgaa catcgtcgta
     3421 accaccattc aaaccagtaa gaagggcttt aagaacgttt acacgagcac cgaagtactg
     3481 gatgttgtgg cgttgttctt cattttctgg atcaagtgga gacacacagc atgagataca
     3541 gctcatttca ccatatccgt ctttagccat tgttgttaca ccttcgtatt ggatagaaga
     3601 gtgtttgtgg ctcatgtgca tacagtagcg acggaagttg tatggcaatt tgtcagtcca
     3661 aagaactgtc aagtttggtt ctggtgagtt accgatgttg tcaagagtgt tcaagaaacg
     3721 gtagtccatc ttagtaacac ggtgacgacc gtcgttaccc ataccagcca tagaagttgt
     3781 gataaaggtt gggtcacctg agtacaattg gtcataagct tttgtacgag caaatttaac
     3841 tgtacgaagt ttcataacga aatcatcaac gaattcttgg atttctgatt cagtaaatgt
     3901 accacgagca aggtcacgtt ctgcaaagat gtccaatacg attggtacac gacctagaga
     3961 tgtagcagca ccgttaatca cacggcagac agccatgaaa gcaatgttaa cccattggat
     4021 tgcttctttc acgttcatcg ctggtttgcg aacatcaacc ccgtaaaggt cacccaggcg
     4081 aacaacttgt tgcaatgctt ggtattgaag gtttacttct tcacgaagac ggattgtttc
     4141 ttcatcgatt tctttgattg cattccagtc gtttactttt tcttgcatca agtagtctgc
     4201 accgtaaaga gcaagacgtg cgtaaacacc gatgatacgt ccgcgtgagt atgcatctgg
     4261 aagaccagtt acagtgtgtg catgacgagc gcgacgaata tttgaagtgt aggcacggaa
     4321 aataccgtcg ttaactgttg ttacatattt agtgaagatt tcgtgaacag ctgggtctgg
     4381 ttcgtatcca ttttctttta aagtagtttc agccatacgg ataccacctt ttggcatgaa
     4441 gttcaatttg aagagttcat cattttggat accaaagata acttcatttt ctttgtcgat
     4501 aaatccagca gggatatcag cgatagatgt tggacgagtg tccattggga aacgagtttc
     4561 ttcgtagtgt gctttagttt cttctacaat tttcttgatg tgaagtgaac gctctgttgg
     4621 tcctgcaagg aagctttcgt ctccatcata aggtgtgtag ttagcttgta caaagcgtga
     4681 tacacttgct ttttctttcc aatctacgcc tttgaagcct tcccaagctt tgtcaaaaat
     4741 atcttgtgct tcaacaaccg tcttaacaac catattaatg tcctcttttt tctagtaaca
     4801 gtcatctgtt acattcataa gacaagtata ccataaagta atcgatttca acaagtgcaa
     4861 aatccctatt tttacacttt cttttctaaa acagtctata ttttatttca aactgtatta
     4921 tatttttgaa aaaaataaag tccttttttc tttttttcag aaaaaagggt ataataaaag
     4981 aaaataagca gtaacactca atggaaatcg aaaagcaaac taggaagcta gccgcaggct
     5041 gctcaaagca ctgctttgag gttgtaaata gaactgacga agtcagctca aaatactgtt
     5101 ttgaggttgc agatggaagc tgacgtggtt tgaagagatt ttcgaagagt ataaaaaggt
     5161 gctaggcatg ttgatttttc ctttgttaaa tgatttgtca agaaaaatca tccatattga
     5221 catggatgcc ttttttgctg cggtggaaat caaggataat cctaaactca gaggaaaacc
     5281 tgtcattatt ggaagcgacc ctcggcaaac aggtggacgg ggagtcgttt ctacctgtag
     5341 ctatgaggct cgagcttttg gtgtccattc tgccatgagt tccaaggaag cttatgaacg
     5401 ttgtccccag gccgtcttta tctcaggaaa ttatgagaaa tacaaagctg tgggactcca
     5461 gattcgagct atttttaagc gctatacaga tttgattgaa cccatgagca ttgacgaagc
     5521 ctatttggat gtgacagaaa ataaactcgg tatcaagtca gcggtcaaaa ttgctcgcct
     5581 cattcaaaaa gatatctggc aagaactcca tctaactgct tctgccggta tttcctacaa
     5641 caagttctta gctaaaatgg cgagtgatta tcaaaaacct catggtttga cagtgattct
     5701 acctgaacag gctgagaatt ttctcaaaca aatggatatt tccaaatttc atggagtagg
     5761 aaaaaagaca gtagaacgtc ttcatcaaat gggcgttttt actggtgctg atttacttga
     5821 agttcctgag gtgaccctaa tagaccgttt tggtagacta ggctatgatc tgtatcgaaa
     5881 ggctcgtggc attcacaact ctccagtcaa atccaatcgc atccgtaaat caatcggcaa
     5941 ggagaaaacc tacgggaaga ttctccgtgc tgaggaagat atcaaaaaag agctgactct
     6001 tctatcagaa aaagtcgctc tcaatctaca tcaacaagaa aaagctggaa aaattgtcat
     6061 tttgaaaatc cgctacgagg acttttcaac tcttaccaaa cgaaaaagtc ttgctcaaaa
     6121 aacacaagat gctagtcaga taagccaaat agccctgcaa ctctatgaag aattaagcga
     6181 gaaagaaaga ggtgtccgcc tattggggat taccctgact ggattttaaa gctcaatg
//
LOCUS       DAVBOD010000089         5588 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 640-05
            SAMEA1012484-rid20186543.denovo.090, whole genome shotgun sequence.
ACCESSION   DAVBOD010000089 DAVBOD010000000
VERSION     DAVBOD010000089.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012484
            Sequence Read Archive: ERR059358
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5588)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5588)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979948.1
            Genome Coverage       :: 595x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:03:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,266
            CDSs (total)                      :: 2,219
            Genes (coding)                    :: 2,091
            CDSs (with protein)               :: 2,091
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 71 of 128
            Pseudo Genes (incomplete)         :: 50 of 128
            Pseudo Genes (internal stop)      :: 33 of 128
            Pseudo Genes (multiple problems)  :: 22 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5588
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012484-rid20186543.denovo.090"
                     /strain="NIG 640-05"
                     /db_xref="taxon:1313"
     gene            331..1377
                     /gene="pheS"
                     /locus_tag="VQ862_002035"
     CDS             331..1377
                     /gene="pheS"
                     /locus_tag="VQ862_002035"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013903845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit alpha"
                     /protein_id="HET3116318.1"
                     /translation="MSTIEEQLKALREETLTSLKQITAGNEKEMQDLRVSVLGKKGSL
                     TEILKGMKDVSAEMRPIIGKHVNEARDVLTAAFEETAKLLEEKKVAAQLASESIDVTL
                     PGRPVATGHRHVLTQTSEEIEDIFIGMGYQVVDGFEVEQDYYNFERMNLPKDHPARDM
                     QDTFYITEEILLRTHTSPVQARAMDAHDFSKGPLKMISPGRVFRRDTDDATHSHQFHQ
                     IEGLVVGKNISMADLQGTLQLIVQKMFGEERQIRLRPSYFPFTEPSVEVDVSCFKCGG
                     EGCNVCKKTGWIEIMGAGMVHPRVLEMSGIDATVYSGFAFGLGQERVAMLRYGINDIR
                     GFYQGDVRFSEQFK"
     gene            1377..1886
                     /locus_tag="VQ862_002036"
     CDS             1377..1886
                     /locus_tag="VQ862_002036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET3116319.1"
                     /translation="MIRKVEMADVEVLAKIAKQAFRETFAYDNTEEQLQEYFEEAYSL
                     KTLSTELGNPDSETYFIMHEEEIAGFLKVNWGSAQTERELEDAFEIQRLYVLQKFQGF
                     GLGKQLFEFALELATKNSFSWAWLGVWEHNTKAQAFYNRYGFEKFSQHHFMVGQKVDT
                     DWLLRKKLR"
     gene            1963..4365
                     /locus_tag="VQ862_002037"
     CDS             1963..4365
                     /locus_tag="VQ862_002037"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002897790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit beta"
                     /protein_id="HET3116320.1"
                     /translation="MLISYKWLKELVDIDVPSQELAEKMSTTGIEVEGVESPAAGLSK
                     IVVGEVLSCEDVPETHLHVCQVNVGEEERQIVCGAPNVRAGIKVMVALPGARIADNYK
                     IKKGKIRGLESLGMICSLGELGISDSVVPKEFADGIQILPEDAVPGEEVFSYLDLDDE
                     IIELSITPNRADALSMCGVAHEVAAIYDKAVNFKEFTLTETNEAAADALSVSIETDKA
                     PYYAARILDNVTIAPSPQWLQNLLMNEGIRPINNVVDVTNYILLYFGQPMHAFDLDNF
                     EGTDIRVREARAGEKLVTLDGEERDLDVNDLVITVADKPVALAGVMGGQATEISEKSS
                     RVVLEAAVFNGKSIRKTSGRLNLRSESSSRFEKGINVATVNEALDAAASLIAELAGAT
                     VRKGIVSAGELDTSDVEVSSTLADVNRVLGTELSYADVEDVFRRLGFGLSGNADSFTV
                     RVPRRRWDITIEADLFEEIARIYGYDRLPTSLPKDDGTAGELTATQKLRRQVRTIAEG
                     AGLTEIITYTLTTPEKAVEFTAQPSNLTELMWPMTVDRSVLRQNMISGILDTVAYNVA
                     RKNKNLALYEIGKVFEQTGNPKEELPNEINSFAFALTGLVAEKDFQTAAVPVDFFYAK
                     GILEALFTRLGLQVTYTATSEIASLHPGRTAVISLGDQVLGFLGQVHPVTAKAYDIPE
                     TYVAELNLSAIEAALQPATPFVEITKFPAVSRDVALLLKAEVTHQEVVDAIQAAGVKR
                     LTDIKLFDVFSGEKLGLGMKSMAYSLTFQNPEDSLTDEEVARYMEKIQASLEEKVNAE
                     VR"
     gene            complement(4433..5434)
                     /locus_tag="VQ862_002038"
     CDS             complement(4433..5434)
                     /locus_tag="VQ862_002038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000597989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HET3116321.1"
                     /translation="MIKTFLSALSVILFVIPIITYSFFPSSNLNIWLSTQPILAQIYA
                     FPLATATMAAILSFLFFFLSFYKKNKQIRFYSGILLLLSLILLLFGTDKTLSSASNKT
                     KTLKLVTWNVANQIEAQHIERIFSHFDADMAIFPELATNIRGEQENQRIKLLFHQVGL
                     SMANYDIFTSPPTNSGIAPVTVIVKKSYGFYTEAKTFHTTRFGTIVLHSRKQNIPDII
                     ALHTAPPLPGLMEIWKQDLNIIHNQLASKYPKAIIAGDFNATMRHGALAKISSHRDAL
                     NVLPPFERGTWNSQSPKLFNATIDHILLPKNHYYVKDLDIVSFQNSDHRCIFTEITF"
BASE COUNT         1665 a         1056 c         1289 g         1578 t
ORIGIN      
        1 tcatcttatt tcaatccgct ataaagttag ataagaataa gctaacaagc agaagtaaga
       61 taggtcttgc aagaatggta aaaatctgat aaactaagtg gtaattgaat agaaatctga
      121 aagactagta gcccaaggga agtatatcag ggaggagagc cgtgactgca agctctctat
      181 atgaaagctg ggtgaattca cttgcgcatg gatttagaaa tgaaggtctg acttgtcaga
      241 tgaaaacgga tggtaccgcg tgtcaacgct ccgagtggag tttttggcat gtggttttct
      301 ttttatctac gagagactga tggaggaaat atgtcaacta ttgaagaaca attaaaagcg
      361 cttcgcgaag aaacgctgac tagcttgaag cagattactg ctggaaatga aaaagagatg
      421 caagatttgc gtgtctctgt ccttggtaaa aagggttcgc tcactgaaat cctcaaaggg
      481 atgaaagatg tttctgctga gatgcgtcca atcatcggga aacacgtcaa tgaagctcgt
      541 gatgtcttga cagctgcttt tgaagaaaca gctaagctct tggaagaaaa gaaagtcgcg
      601 gctcaactgg ctagcgagag tatcgatgtg acgcttccag gtcgtccagt tgcgactggt
      661 caccgtcacg ttttgacaca aaccagtgaa gaaatcgaag atatcttcat cggtatgggt
      721 tatcaagtcg tggatggttt tgaagtggag caagactact ataactttga acgtatgaac
      781 cttccaaaag accacccagc tcgtgatatg caggatactt tctatatcac tgaagaaatc
      841 ttgctccgta cccacacgtc tccagttcag gcgcgtgcta tggatgccca tgatttttct
      901 aaaggtcctt tgaagatgat ctcgccaggg cgtgtcttcc gtcgcgatac ggacgatgcg
      961 acccacagtc accaattcca ccaaatcgaa ggcttggtag ttgggaaaaa tatctctatg
     1021 gctgatcttc aaggaacgct tcagttgatt gtccaaaaaa tgtttggtga agagcgtcaa
     1081 attcgtttgc gtccatctta cttcccattc acagagccat ctgttgaggt ggatgtttct
     1141 tgcttcaagt gtggtggaga aggctgtaac gtatgtaaga aaacaggttg gatcgaaatt
     1201 atgggagccg gtatggttca cccacgtgtc cttgaaatga gtggtatcga tgcgactgta
     1261 tactctggtt ttgcctttgg tcttggacaa gagcgtgtag ctatgctccg ttatggaatc
     1321 aacgatatcc gtggattcta ccaaggagat gtccgcttct cagaacagtt taaataatga
     1381 ttagaaaagt agaaatggca gatgttgagg tgttggctaa aattgccaaa caagcctttc
     1441 gtgaaacctt tgcgtatgat aatacggaag agcagttaca ggaatacttt gaagaggctt
     1501 atagtctgaa aactttgtca actgagttgg gaaatcctga ctctgaaacc tatttcatta
     1561 tgcatgagga ggagatagct ggttttctca aagtcaactg gggaagtgct caaactgaga
     1621 gagaattaga ggacgctttt gaaattcaac gcctctatgt gctacaaaaa ttccaaggat
     1681 ttggactagg taagcaactg tttgaattcg cacttgaact tgctacaaaa aatagttttt
     1741 cttgggcttg gctaggtgtt tgggagcata atacaaaagc tcaagcgttt tataatcgat
     1801 atggttttga aaaatttagc caacatcatt ttatggttgg tcaaaaagta gatacggatt
     1861 ggttactgag aaagaaatta aggtaagaag aggattcttc tattgaaatg ataggaaagg
     1921 aaaagaacca gtgtggcaat ggtcattctg gagaactaaa ttatgcttat atcttataaa
     1981 tggttaaaag aattggtgga cattgatgtg ccatcacaag agttggctga aaaaatgtca
     2041 actacaggaa tcgaggtcga aggtgtcgaa tcaccagctg ctggtctctc aaaaattgtc
     2101 gtcggtgagg tcttgtcttg cgaagatgtg ccagagactc acctccatgt ttgtcaggtt
     2161 aacgttggcg aagaagagcg tcagatcgtt tgtggtgccc caaatgtgcg tgctgggatc
     2221 aaggtcatgg tggctcttcc aggagctcgt atcgctgata actacaaaat caaaaaagga
     2281 aaaatccgtg gtttggagtc acttggaatg atctgttcac ttggtgaatt gggaatttct
     2341 gactcagttg tgcctaagga attcgcagat ggcatccaaa tcttgcctga agatgccgtg
     2401 ccaggtgagg aagtcttttc ttacctagac ttggatgatg aaatcatcga actttccatc
     2461 acaccaaacc gtgcagatgc cctttctatg tgtggagtgg ctcacgaagt ggcagccatc
     2521 tatgacaagg cagtcaactt taaagaattt actctaacag aaactaatga agctgcggca
     2581 gatgcccttt ctgtcagcat tgagacagac aaggcgcctt actatgcagc tcgtatcttg
     2641 gacaatgtga ccatcgcacc aagtccacaa tggttgcaaa accttctcat gaacgaagga
     2701 atccgtccca tcaataacgt agtggacgtg accaactaca tcctgctcta ttttggtcaa
     2761 ccaatgcatg cctttgactt ggataacttt gaagggactg acatccgtgt gcgtgaagcg
     2821 cgtgctggtg aaaaattggt gaccttggac ggtgaagaac gtgacttgga cgtgaatgac
     2881 ctagtcatca ctgtcgcaga caagccagta gcccttgcag gtgtcatggg tggtcaagca
     2941 acagaaatct ctgaaaaatc tagtcgtgtt gtccttgaag ctgctgtttt caatggcaaa
     3001 tctatccgta agacaagtgg tcgcctgaac cttcgttctg agtcatcttc tcgctttgaa
     3061 aaaggaatta atgtggcaac agttaatgaa gcccttgatg cggcagctag cctgattgcg
     3121 gaacttgcag gtgcgacggt gcgtaagggc atcgtttcag cgggtgagct tgatacttca
     3181 gatgtagaag tttcttcaac ccttgctgat gttaaccgtg tcctcggaac tgagctgtct
     3241 tatgctgatg tagaagacgt cttccgtcgt cttggctttg gtctttctgg aaatgcagac
     3301 agctttacag tcagagtccc acgtcgtcgt tgggatatca caatcgaagc tgacctcttt
     3361 gaagaaattg ctcgtatcta tggttatgac cgcttgccaa ctagtctacc aaaagacgat
     3421 ggtacagcag gtgaattgac agccacacaa aaactccgcc gtcaagttcg tactattgct
     3481 gaaggagcag gtttgacaga aatcatcacc tatactctaa caactcctga aaaagcagtt
     3541 gagtttacgg ctcaaccaag taaccttacg gaactcatgt ggccaatgac tgtggatcgt
     3601 tcagtcctcc gtcaaaatat gatttcaggt atccttgata ccgttgccta caacgtggct
     3661 cgtaagaata aaaacttggc cctttacgag attggaaaag tctttgaaca aacaggtaat
     3721 ccaaaagaag aacttccaaa tgaaatcaac agttttgcct ttgccttgac aggcttggtt
     3781 gctgaaaaag atttccaaac agcagcagtt ccagttgatt tcttctatgc taagggaatc
     3841 cttgaagccc tatttactcg tttgggactc caagtaacct atacagcaac atctgaaatc
     3901 gctagccttc atccaggtcg tacagccgtg atttcactcg gtgaccaagt tcttggtttc
     3961 cttggccaag tgcatccagt cactgccaag gcttacgata ttccagaaac gtatgtggct
     4021 gagcttaacc tttcagctat cgaagctgcg cttcagccag cgactccatt tgtagaaatc
     4081 accaaattcc cggcagtcag ccgtgacgtt gcccttctcc tcaaggcaga agtgactcat
     4141 caagaagttg tagatgctat ccaagctgcc ggcgtgaaac gtttgacaga tatcaaactc
     4201 tttgacgtct tctcaggtga gaaattggga cttggtatga agtcaatggc ttatagcttg
     4261 accttccaaa atccagaaga tagcttaacg gacgaagaag tcgcacgcta tatggaaaaa
     4321 atccaagcat cgctcgaaga aaaagtcaat gcagaagtgc gttaaacgat agtatgatac
     4381 aaattccccc tctagtttat gaacactaga ggggtgattt tatataaaat aattaaaatg
     4441 tgatttctgt aaaaatacat ctatgatcag agttttgaaa acttacaatg tctaaatctt
     4501 taacatagta gtggttttta ggcaataaaa tatgatctat tgttgcatta aaaagttttg
     4561 gactttggct attccaagtt cctctttcaa aaggtggcag tacatttaat gcgtccctat
     4621 gagagcttat ttttgcaagt gctccatgac gcatagttgc attaaaatca cctgcaataa
     4681 tagcctttgg atattttgaa gccaattgat tatgaatgat gtttaagtct tgcttccaga
     4741 tttccattaa acctggcaga ggaggagcag tatgcaaggc aatgatatct ggtatatttt
     4801 gttttctcga atgtaataca attgtcccga accgtgttgt atgaaaagtt ttagcttctg
     4861 tatagaaacc ataacttttc ttgacaatca cagtcacagg agctattcca ctattggtag
     4921 gtggagaagt gaaaatatca tagttggcca tagaaagtcc aacttgatga aacaatagtt
     4981 tgattctctg gttttcttgc tcacctctga tattggtagc tagttcaggg aatatagcca
     5041 tatcggcgtc aaaatggcta aaaattcgct caatatgttg tgcttctatt tgattagcga
     5101 cgttccaagt tactaatttt aaggttttag tcttatttga tgcagaagaa agggttttat
     5161 ctgttccgaa taatagtaat atgagcgata gtaagagcaa aatgccagag taaaaccgta
     5221 tttgtttatt tttcttgtaa aaagatagga aaaaaaataa gaaacttaaa atagcagcca
     5281 tagttgcagt agctaagggg aaggcataaa tctgtgccaa gataggttgg gtagatagcc
     5341 aaatgttaag attagaagat gggaaaaaag aataagttat gatagggata acaaagagaa
     5401 tgaccgaaag ggcagagaga aatgttttaa tcattgtgtg agtacctcaa tttgcaatgg
     5461 ttgctcggag ctaatgtgac tttgtgactt tacttgattg atattctttt tcttgtcttc
     5521 ctcatagatt aagtacaacc caagtaaaaa aagtccaatt taagattgaa atgattaaaa
     5581 ggcacaga
//
LOCUS       DAVBOD010000090         5511 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 640-05
            SAMEA1012484-rid20186543.denovo.091, whole genome shotgun sequence.
ACCESSION   DAVBOD010000090 DAVBOD010000000
VERSION     DAVBOD010000090.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012484
            Sequence Read Archive: ERR059358
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5511)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5511)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979948.1
            Genome Coverage       :: 595x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:03:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,266
            CDSs (total)                      :: 2,219
            Genes (coding)                    :: 2,091
            CDSs (with protein)               :: 2,091
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 71 of 128
            Pseudo Genes (incomplete)         :: 50 of 128
            Pseudo Genes (internal stop)      :: 33 of 128
            Pseudo Genes (multiple problems)  :: 22 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5511
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012484-rid20186543.denovo.091"
                     /strain="NIG 640-05"
                     /db_xref="taxon:1313"
     gene            80..718
                     /locus_tag="VQ862_002039"
     CDS             80..718
                     /locus_tag="VQ862_002039"
                     /EC_number="2.7.4.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTMP kinase"
                     /protein_id="HET3116322.1"
                     /translation="MSKGFLVSLEGPEGAGKTSVLEALLPILEEKGVKVLTTREPGGV
                     LIGEKIREVILDPSHTQMDAKTELLLYIASRRQHLVEKVLPALEAGKLVIMDRFIDSS
                     VAYQGFGRGLDIEAIDWLNQFATDGLKPDLTLYFDIEVEEGLARIAANSDREVNRLDL
                     EGLDLHKKVRQGYLSLLDKEGNRIVKIDASLPLEQVVETTKAVLFDGMGLAK"
     gene            715..1605
                     /locus_tag="VQ862_002040"
     CDS             715..1605
                     /locus_tag="VQ862_002040"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000806705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta'"
                     /protein_id="HET3116323.1"
                     /translation="MKQDQLKAWQPAQFDRFVRILEQDQLNHAYLFSGFFGSLEIAQF
                     LAKSLFCTDKVGVLPCEKCRSCKLIEQGEFPDVTLIKPVNQVIKTERIRELVGQFSQA
                     GIESQQQVFIIEQADKMHPNAANSLLKVIEEPQSEVYIFFLTSDEEKMLPTIRSRTQI
                     FHFKKQEEKLILLLEQMGLVKKKATLLAKFSQSRAEAEKLANQASFWTLVDESERLLT
                     WLVAKKKESYLQVAKLANLADDKEKQDQVLRILEVLCGQDLLQVRVRVILQDLLEARK
                     MWQANVSFQNAMEYLVLKEI"
     gene            1645..1962
                     /gene="yabA"
                     /locus_tag="VQ862_002041"
     CDS             1645..1962
                     /gene="yabA"
                     /locus_tag="VQ862_002041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication initiation control protein YabA"
                     /protein_id="HET3116324.1"
                     /translation="MDKKELFDALDDFSQQLLVTLADVEAIKKNLKSLVEENTALRLE
                     NSKLRERLGEVEADAPVKAKHVRESVRRIYRDGFHVCNDFYGQRREQDEECMFCDELL
                     YRE"
     gene            1965..2834
                     /gene="rsmI"
                     /locus_tag="VQ862_002042"
     CDS             1965..2834
                     /gene="rsmI"
                     /locus_tag="VQ862_002042"
                     /EC_number="2.1.1.198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001166894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (cytidine(1402)-2'-O)-methyltransferase"
                     /protein_id="HET3116325.1"
                     /translation="MQIQKSFKGQSPYGKLYLVATPIGNLDDMTFRAIQTLKEVDWIA
                     AEDTRNTGLLLKHFDISTKQISFHEHNAKEKIPDLIGFLKAGQSIAQVSDAGLPSISD
                     PGHDLVKAAIEEEIAVVTVPGASAGISALIASGLAPQPHIFYGFLPRKSGQQKQFFDS
                     KKDYPETQIFYESSHRVADTLENMLEVYGDRSVVLVRELTKIYEEYQRGTISELLESI
                     AETPLKGECLLIVEGASQDVEEKDEEDLFLEIQARIQQGMKKNQAIKEVAKIYQWNKS
                     QLYAAYHDWEEKQ"
     gene            3061..3579
                     /locus_tag="VQ862_002043"
     CDS             3061..3579
                     /locus_tag="VQ862_002043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013852041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClbS/DfsB family four-helix bundle protein"
                     /protein_id="HET3116326.1"
                     /translation="MRTYENKEELKAEIEKTFEKYILEFDNIPENLKDKRADEVDRTP
                     AENLAYQVGWTNLVLKWEEDERKGLQVKTPSDKFKWNQLGELYQWFTDTYAHLSLQEL
                     KAKLNENINSISAMIDSLSEEELFEPHMRKWADEATKTATWEVYKFIHVNTVAPFGTF
                     RTKIRKWKKIVL"
     gene            3688..4335
                     /locus_tag="VQ862_002044"
     CDS             3688..4335
                     /locus_tag="VQ862_002044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000345255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HET3116327.1"
                     /translation="MDFEYFYNREAERFNFLKVPEILVDREEFRGLSAEAIILYSILL
                     KQTGMSFKNNWIDKEGRVFIYFTVEEIMKRRNISKPTAIKTLDELDVKKGIGLIERVR
                     LGLGKPNIIYVKDFMSIFQVKENDLQKSKNLTSEVKDFNLRSKENELQEVKNLDSNYI
                     ENNKSKYSKREYSFGENGLGTFQNVFLAAEDISDLQIIMNSQLENYIRLPAKLES"
     gene            complement(4324..5129)
                     /locus_tag="VQ862_002045"
                     /pseudo
     CDS             complement(4324..5129)
                     /locus_tag="VQ862_002045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5 family transposase"
     gene            5124..5378
                     /locus_tag="VQ862_002046"
     CDS             5124..5378
                     /locus_tag="VQ862_002046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001244258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HET3116328.1"
                     /translation="MHRTTIPYFVSQEVYWKVRNIGAEAIRRNCERGAIFSGKIKHHE
                     DSQFKGEHYVECYAVLDNTVIARDRITVPIDPLCGKDFIE"
BASE COUNT         1796 a          913 c         1214 g         1588 t
ORIGIN      
        1 aaatgagaag acaaaaagat tgtcacaaac ccctattttt ttgatagaat agaagtagta
       61 aaaaagaaat gagttagaca tgtcaaaagg atttttagtc tctcttgagg gaccagaggg
      121 agcaggcaag accagtgttt tagaggctct gctaccaatt ttagaggaaa aaggagtaaa
      181 ggtgctgacg acccgtgaac ctggcggagt cttgattggg gagaagattc gggaagtgat
      241 tttggatcca agtcatactc agatggatgc taaaacagag ctacttctct atattgccag
      301 tcgcagacag catttggtgg aaaaagttct tccagccctt gaagctggca agttggtcat
      361 catggatcgt tttatcgata gttctgttgc ctatcaggga tttggtcgtg gcttagatat
      421 tgaagccatt gactggctca atcagtttgc gacagatggc ctcaaacccg atttgacact
      481 ctattttgac atcgaggtgg aagaagggct ggctcgtatt gctgctaata gtgaccgcga
      541 ggttaatcgt ttggatttgg aagggttgga cttgcataaa aaagttcgtc aaggctacct
      601 ttctcttctg gataaagagg gaaatcgcat tgtcaagatt gatgctagtc tccctttgga
      661 gcaagttgtg gaaactacca aggctgtctt gtttgacgga atgggcttgg ccaaatgaaa
      721 caagatcaac taaaggcttg gcaaccagct cagtttgacc gttttgtccg tatcttagaa
      781 caagaccagc tcaatcacgc ctatctcttt tcaggtttct ttggaagctt ggaaatagcg
      841 caatttttag ctaagagcct cttttgtacg gataaagttg gcgtcttacc atgtgagaaa
      901 tgccgaagtt gcaagctgat tgaacaggga gaatttcccg atgtcacctt gattaagcca
      961 gtcaatcagg tcatcaagac agaacgcatt agggaattgg tgggacagtt ttctcaagca
     1021 gggattgaaa gccagcaaca ggtctttatc atcgagcaag cggataaaat gcatcccaac
     1081 gcagccaatt ctctgctcaa ggtcatcgaa gaaccccaga gtgaagttta tattttcttc
     1141 ttgactagcg atgaggaaaa gatgttaccg acaatccgaa gtcggaccca gatcttccac
     1201 tttaaaaagc aagaagaaaa acttatctta ctcttagaac aaatgggact tgttaagaaa
     1261 aaagcgactc ttttagctaa gtttagtcaa tcgcgagctg aagcagaaaa gttggctaat
     1321 caggcaagtt tttggacctt ggtcgatgaa agtgaacgcc tgctgacttg gttagtagct
     1381 aagaaaaaag aaagttatct acaggttgcc aaattagcca acttggcaga tgataaggaa
     1441 aaacaggatc aggttttacg gattcttgaa gttctctgtg ggcaggacct cttgcaggta
     1501 agagtaagag tgattctaca agatttacta gaagctagaa aaatgtggca agctaatgtc
     1561 agctttcaaa atgccatgga atatctggtc ttgaaagaaa tataaactca aaaatgaatg
     1621 ataaagaaag gaaagagctg ttttatggac aaaaaagaat tatttgacgc gctggatgat
     1681 ttttcccaac aattattggt aaccttggcc gatgtggaag ccatcaagaa aaatctcaag
     1741 agcctggtag aggaaaatac agctcttcgc ttggaaaata gtaagttgcg agaacgcttg
     1801 ggtgaggtgg aagcagacgc tcccgtcaag gccaagcatg ttcgcgaaag tgtccgtcgt
     1861 atttaccgtg atggatttca cgtatgtaat gatttttatg gacaacgtcg agagcaggac
     1921 gaagaatgta tgttctgtga tgagttgtta tacagggagt aggcatgcaa attcaaaaaa
     1981 gttttaaggg gcagtctccc tatggcaagc tgtatctagt ggcaacgccg attggcaatc
     2041 tagatgatat gacttttcgc gctatccaga ccttgaaaga agtggactgg attgctgctg
     2101 aggatacgcg caatacaggt cttttgctca agcattttga catttccacc aagcagatca
     2161 gttttcatga gcacaatgcc aaggaaaaaa ttcctgattt gattggtttc ttgaaagcag
     2221 ggcaaagtat tgctcaggtc tctgatgccg gtttgcctag catttcagac cctggtcatg
     2281 atttggttaa ggcagctatt gaggaagaaa ttgcagttgt gactgttcca ggtgcctctg
     2341 caggaatttc tgccttgatt gccagtggtt tagcgccgca gccacatatc ttttacggct
     2401 ttttaccgag aaaatcaggt cagcaaaagc aatttttcga ctcgaaaaaa gactatcctg
     2461 aaactcagat tttttatgaa tcgtcccatc gtgtggcaga tacattggaa aatatgctag
     2521 aagtctacgg tgaccgctcg gtagtcttgg tcagggaatt gactaaaatc tatgaagaat
     2581 accaaagagg taccatttct gaattgctgg aaagcatcgc tgaaacgcca ctcaagggcg
     2641 aatgccttct tattgttgaa ggtgccagtc aggatgtgga ggaaaaagac gaggaggact
     2701 tgttcttaga aatccaagcc cgtatccagc aaggcatgaa gaaaaatcaa gctattaagg
     2761 aagtagctaa gatttaccag tggaataaga gtcaactcta cgctgcctac cacgattggg
     2821 aagaaaaaca ataaagggag acagaatgta ataattctgt ctgtttctgt ttaacttaat
     2881 tagtgatggt aatataaaga tgtatcactt ggtatagaag ctttggtatt aagtttttta
     2941 ttaagcccat acggaatacc gatggttgga gcagcagtta tagcgttctt agaaggtata
     3001 aatagaaaaa taaggtcatt ttaaatcaaa ggattgataa atcagaaaga aggtgatttt
     3061 ttgcgaacat acgaaaataa agaagaacta aaagctgaga tagagaaaac atttgagaaa
     3121 tatattttag aatttgataa tattccagaa aatttaaaag ataagagagc tgatgaagtt
     3181 gacagaactc cagcagaaaa ccttgcttat caggttggtt ggaccaactt ggttcttaaa
     3241 tgggaagaag atgaaagaaa ggggcttcaa gtaaaaacac catcggataa atttaaatgg
     3301 aatcaacttg gtgaattata tcagtggttc acagatacct acgctcattt atctctgcaa
     3361 gagttgaaag caaaattaaa tgaaaatatt aattctatct ctgcaatgat tgattcgttg
     3421 agtgaggaag aattatttga accgcatatg agaaagtggg ctgatgaagc gactaaaaca
     3481 gcgacttggg aagtgtataa gtttattcat gtaaatacgg ttgcaccttt tggaactttc
     3541 agaactaaaa tcagaaaatg gaagaagata gtattataaa ttatattttt aactttaaaa
     3601 aatttcataa aaatggttac caaaggcgat agaagaaaaa ctatcgtctt tttctttgca
     3661 aatttttaag aagggaggtg atcttgcatg gactttgaat atttttataa cagagaagcg
     3721 gaaagattta acttcttaaa agtaccggag atattagttg atagagaaga atttcggggc
     3781 ttatcagcag aagcaattat cctttattcc atacttctta aacagacagg aatgtcattt
     3841 aagaataact ggatagacaa ggaaggcaga gtatttatct attttactgt cgaagaaatt
     3901 atgaaaagaa gaaatatctc aaagccaact gccataaaaa cattagatga gcttgatgta
     3961 aaaaaaggaa taggactgat cgaaagagta aggcttggac ttggtaagcc gaacatcatt
     4021 tatgttaaag actttatgag tatatttcag gtaaaagaaa atgacttaca gaagtcaaaa
     4081 aacttaactt cagaagtaaa agattttaac ctcagaagta aagaaaatga acttcaagag
     4141 gttaagaacc ttgactctaa ctatatagag aataataaga gtaagtatag taagagagaa
     4201 tatagttttg gtgaaaacgg acttggaaca tttcaaaatg tgtttttagc tgctgaagat
     4261 atatcggatt tacaaatcat aatgaactca cagcttgaga attacattag acttcctgca
     4321 aaactagaat cctagttcat gattgataat accagcaatc aaattcattc gtaatccgaa
     4381 gcgtttacga tgatttcgat aggttgttga aaacatttta aacgttttta ctttggcaaa
     4441 gatgttctca accttgcttc tctccttaga tagcgcatgg ttacaggctt tatcttcagc
     4501 tgttagcggc ttgagtttgc tggatttacg tggagtttgt gcttgaggat atatcttcat
     4561 gagcccttga taaccactgt cggccaagat tttaccagct tgtccgatat ttctacaact
     4621 cattttgaac aacttcatat catgactata gttcacagcg atatccaaag aaacaattct
     4681 cccttgactt gtgacaatcg cttgagcctt catagcgtga aatttctttt taccagaatg
     4741 attcgctaat tgttttctta gggcgattga tttgtacttc cgtcgcatca atcattaccg
     4801 tgtcctcaga actgagagga gttcttgaaa tcgtaacacc acctttgaac aagagttact
     4861 tcaacccatt ggctccgacg gagtaagttg ctttcgtgga taccaaaatc agccgcaatt
     4921 tattcataag tgcgatattc tcgcacatat tgaagagtgg ccataagaag gtcttctagg
     4981 cttaatttag gttttcgtcc accttttgcg tatttaagtt gataagctgt ttttaataca
     5041 gctaatatct cttcaaaagt cgtgcgctga acaccaacaa gacgcttaaa tcgtgcatca
     5101 gttagttgtt tacttgcttc ataattcata gaactactat accatatttt gtttcgcagg
     5161 aagtctattg gaaagtaaga aatattggag ctgaggcgat tagaagaaat tgtgagcgtg
     5221 gtgctatttt ttcaggtaaa ataaaacatc acgaagattc tcagtttaaa ggagagcact
     5281 atgttgaatg ttatgctgtt ttagataata cggttatagc aagagataga ataacagtcc
     5341 ctatcgatcc gttatgtgga aaagatttta tagagtagca tataattgat tcttaactgg
     5401 aatactctct atctctttac atcaagaaaa tgactaaaca gggaagtttg ccttcttccc
     5461 tttttttgtt atactagtag aagaaaaaaa tagaaagatt tgtgggagtg a
//
LOCUS       DAVBOD010000091         5198 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 640-05
            SAMEA1012484-rid20186543.denovo.092, whole genome shotgun sequence.
ACCESSION   DAVBOD010000091 DAVBOD010000000
VERSION     DAVBOD010000091.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012484
            Sequence Read Archive: ERR059358
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5198)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5198)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979948.1
            Genome Coverage       :: 595x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:03:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,266
            CDSs (total)                      :: 2,219
            Genes (coding)                    :: 2,091
            CDSs (with protein)               :: 2,091
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 71 of 128
            Pseudo Genes (incomplete)         :: 50 of 128
            Pseudo Genes (internal stop)      :: 33 of 128
            Pseudo Genes (multiple problems)  :: 22 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5198
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012484-rid20186543.denovo.092"
                     /strain="NIG 640-05"
                     /db_xref="taxon:1313"
     gene            complement(134..268)
                     /gene="rpmH"
                     /locus_tag="VQ862_002047"
     CDS             complement(134..268)
                     /gene="rpmH"
                     /locus_tag="VQ862_002047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L34"
                     /protein_id="HET3116329.1"
                     /translation="MKRTYQPSKLRRARKHGFRNRMSTKNGRRVLAARRRKGRKVLAA
                     "
     gene            complement(413..1627)
                     /locus_tag="VQ862_002048"
     CDS             complement(413..1627)
                     /locus_tag="VQ862_002048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011836593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HET3116330.1"
                     /translation="MKEYNKSSKLEHVAYDIRGPVLEEAMRMRANGEKILRLNTGNPA
                     EFGFTAPDEVIHDLIMNARDSEGYSDSKGIFSARKAIMQYCQLKKFPNVDIDDIYLGN
                     GVSELIVMSMQGLLDNGDEVLVPMPDYPLWTAAVSLAGGNAVHYICDEAVEWYPDIDD
                     IKSKITSNTKAIVLINPNNPTGALYPKELLLGIIEIARQNDLIIFADEIYDRMVMDGH
                     VHTPVASLAPDVFCVSMNGLSKSHRIAGFRVGWMVLSGPKTHVKGYIEGLNMLSNMRL
                     CSNVLAQQVVQTSLGGHQSVDELLLPGGRIYEQRNFIYNAIQDIPGLSAVKPKAGLYI
                     FPKIDRNMYRIDDDEQFVLDFLKQEKVLLVHGRGFNWQEPDHFRIVYLPRVDELAQIQ
                     EKMTRFLKQYRR"
     gene            complement(1783..2076)
                     /locus_tag="VQ862_002049"
     CDS             complement(1783..2076)
                     /locus_tag="VQ862_002049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009014348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3116331.1"
                     /translation="MMKNSFQKSNFLYYGIILVSVLVEVIMIWQLESLVPLIYPGFIG
                     FLVFHVLYHLILFLVAKRSGRWDYLMIWGLFLMFNLLYDSFLGLLFLGLSFGM"
     gene            2238..2690
                     /locus_tag="VQ862_002050"
     CDS             2238..2690
                     /locus_tag="VQ862_002050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000079155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HET3116332.1"
                     /translation="MAQRYQNIMVAIDGSKEADLAFVKGVHSALRNDAKLTIVHVIDT
                     RALQSVSTFDAEVYEELQVDAESLMKEYEKRAKDAGVADVHIVIEMGNPKTLLARTIP
                     DAEEVDLILVGATGLNAFERLLVGSSSEYILRHAKVDLLVVREQEKTL"
     gene            complement(2725..4113)
                     /locus_tag="VQ862_002051"
     CDS             complement(2725..4113)
                     /locus_tag="VQ862_002051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000453140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HET3116333.1"
                     /translation="MEVKAVFFDIDGTLVNNRKSVLKSTKDAIKIVKEQGVLVGVATG
                     RGPFFVKELMDDLDLDFAVTYNGQYIFSKDRVLFTSPISKLHLRHLISYAKKEGTEIA
                     LGTKDAMLGSKIMSFGLGSFSQRISRFVPSVLTRTVSQSFNRMVSKVVPQKEEDLLHL
                     MNQPIYQVLMLMTPEESEKAAADFEDLKLTRSNPFASDVINQGNSKLEGIRRVGKEYG
                     FDLNQVMAFGDSDNDLEMLAGVGMSVAMGNGSSSVKEAAKHITTSNQQDGIHKALEHF
                     GVLSSEKVFVSRDYHFNKVKTFHHMMDERTQEEPRAWDLEGATHRAGFKIEELVEFVR
                     AASPSEEDFGQAVSQLHQALDKAAGKVAKKTPAQQDLIGQVDALIDTLYFTYGSFVLM
                     GVDPERIFDIVHQANMGKIFPDGKAHFDPVTHKILKPDNWEEKYAPEPAIKKELQRQL
                     KAYERHKERNKS"
     gene            4179..5141
                     /locus_tag="VQ862_002052"
     CDS             4179..5141
                     /locus_tag="VQ862_002052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparaginase"
                     /protein_id="HET3116334.1"
                     /translation="MPKKILVLHTGGTISMQADASGAVVTSSDNPMNHVSNPLEGIQV
                     HALDFFNLPSPHIKPKHMLVLYQKIKEEADNYDGVVITHGTDTLEETAYFLDTMEVPH
                     MPIVLTGAMRSSNELGSDGVYNYLSALRVASDDRAADKGVLVVMNDEIHAAKYVTKTH
                     TTNVSTFQTPTHGPLGLIMKQEILYFKTAEPRVRFDLDHIQGLVPIISAYAGMTDELI
                     DMLDLEHLDGLIIQAFGAGNIPKETAQKLESLLQKGIPVALVSRCFNGIAEPVYAYQG
                     GGVQLQKAGVFFVKELNAQKARLKLLIALNAGLTGQALKDYMEG"
BASE COUNT         1509 a         1204 c         1018 g         1467 t
ORIGIN      
        1 cagaggtgta ctattctagt ttcaatctac tataacatcg cttccgaatc catttgcatc
       61 tactgaactt ttttacaaaa ataaaaatca gtagactcga gttcctactg atttttgata
      121 gaattcgttt ggattatgca gccaaaactt tgcgtccttt acgacgacga gctgccaata
      181 cgcgacgacc atttttagtt gacatacggt tacggaatcc gtgtttgcgc gcacgacgaa
      241 gtttacttgg ttgataagta cgtttcacga tgaatacctc ctcatagatt ttgtattcgt
      301 ttagccggct ataaagtgat cagttactaa acatacttta ctattctatc tgattctttc
      361 acttttgtca atagctctag gcaaatgttt ccagcttttt cgaatgcaag ccctatctac
      421 gatactgttt caagaaacga gtcatctttt cttggatttg ggctaactca tcaacacgag
      481 gaaggtaaac gatacggaag tggtctggtt cctgccagtt aaagcctcga ccatgaacca
      541 agagaacctt ttcctgcttc aagaaatcaa ggacaaactg ctcatcatca tcgatacggt
      601 acatattgcg gtcgattttt gggaagatat agagccccgc cttgggttta acggcagaca
      661 aacctggaat atcttgaatg gcattataga tgaaatttct ttgctcgtag attcgtccac
      721 caggaagaag caattcatcg actgattggt gaccccccaa ggaagtttgt acgacttgtt
      781 gggccaaaac gttagagcaa aggcgcatat tggacagcat attgagccct tcgatatagc
      841 ccttaacatg agtcttaggg ccagacaaga ccatccaacc cacacggaaa cctgctatgc
      901 ggtgggattt tgacagacca ttcatgctga cacagaagac atctggtgcc aagctcgcca
      961 caggcgtatg cacatgtccg tccattacca tgcggtcata gatttcatcc gcaaagataa
     1021 tcaaatcgtt ttgacgggca atctcaataa tccccagcaa gagttcctta ggataaaggg
     1081 ctccagttgg gttatttgga ttgataagga caattgcctt ggtattggaa gtgatttttg
     1141 acttgatatc gtcaatatct gggtaccatt ccacagcttc atcacagata tagtgaacgg
     1201 catttcctcc agctaggctg acagccgccg tccatagagg atagtctggc attggcacta
     1261 agacctcatc cccattgtcc aaaagcccct gcatggacat gacaatcaac tcactgacac
     1321 catttccaag gtaaatatca tcaatatcta cgtttgggaa tttcttcagc tggcaatact
     1381 gcatgatggc cttacgggct gagaaaatcc ctttggagtc agaatagcct tcactatcac
     1441 gcgcattcat aatcaagtca tgaatgacct cgtctggcgc tgtaaagcca aattctgctg
     1501 gatttcctgt attcagacgt aaaatctttt ctccattcgc tcgcatccgc atggcttctt
     1561 ccaatacagg accacggata tcataagcaa catgctctaa cttactagac ttgttatatt
     1621 ctttcatctt gtttcctcaa ttcatcagga tagtaacatt ataccactag aaagagaatg
     1681 cgacaagttt actgaaatgt gttactagtt tcgtatagaa gaaaaacctt gctaaaggcg
     1741 aggttaagaa cgtagagata gcaggtattt tgcaaagaca catcacatac caaaagataa
     1801 acctagaaaa agcaagccta gaaaggagtc ataaagaaga ttaaacatga ggaaaagccc
     1861 ccatatcatc aagtaatccc aacgcccact tcgttttgca actagaaata agattagatg
     1921 gtagagtaca tgaaagacta aaaatccaat aaaacctgga taaataagcg gtaccaaact
     1981 ctctaattgc cagatcatga tcacttctac caagactgaa actaggataa ttccataata
     2041 caggaaattt gatttttgaa aagagttttt catcattctc ccttccttca cttctttcct
     2101 gctatccttt cttttatttt atcatatatt tatatagatt ttaagcccta atattctttt
     2161 gaaaaatact ttttttgctt tacttctata gtgaaaaggt ttacaattat agtaagaaaa
     2221 tttcaggagg tttcattatg gcacaacgtt accaaaatat catggtcgca atcgatggtt
     2281 ctaaggaagc ggacttggct tttgtcaagg gagttcattc tgctctacga aacgacgcta
     2341 aactcaccat cgtacatgtc attgacacac gcgctctcca aagcgtatcc acctttgatg
     2401 ctgaagttta cgaagaactc caagtcgacg ctgaaagtct gatgaaagag tacgaaaaac
     2461 gtgctaaaga tgctggggta gcagatgttc atatcgtcat tgaaatggga aatccaaaga
     2521 ccctgctagc acgtactatt ccagatgccg aggaagtgga cctcatcctc gttggcgcaa
     2581 ctggtctcaa cgcctttgaa cgcctcttag tcggctcttc atctgaatac atactccgcc
     2641 atgctaaggt cgatttgctg gttgtgagag aacaagaaaa aaccttataa tcacaaagaa
     2701 aaggagcccc tagctccttt ttgtttacga tttatttctc tctttatggc gttcgtaagc
     2761 cttgagctgg cgctgcagtt cctttttaat agcaggttct ggagcatatt tttcttccca
     2821 attatctggt tttaagattt tatgggtcac tggatcaaaa tgagccttgc catctggaaa
     2881 aattttcccc atattggcct gatggacaat atcaaaaata cgttctgggt ccacccccat
     2941 caagacaaaa ctgccgtagg tgaagtaaag cgtgtcaatc aaggcatcca cttgccctat
     3001 caaatcttgc tgagcaggtg tcttcttggc tactttacct gctgccttat caagggcctg
     3061 atgaagttgc gatacagctt gaccaaaatc ttcttcagaa ggactggctg ctcgaacaaa
     3121 ctccaccaat tcttctattt taaaaccagc cctatgggtt gcaccctcta aatcccaagc
     3181 tcgaggttct tcttgggttc gttcatccat catgtggtgg aaggtcttga ccttattgaa
     3241 atgatagtca cggctgacaa agactttttc tgaagacaaa acaccaaaat gttccaaggc
     3301 cttgtggatc ccatcttgtt gattgctagt ggtaatgtgc ttggcagctt ccttgacact
     3361 gctactacca tttcccatag cgaccgacat accgacgcca gccagcattt caaggtcatt
     3421 atctgagtca ccaaaagcca tgacttggtt gaggtcaaag ccatattctt tcccaactcg
     3481 gcgaatgcct tctaatttag aatttccctg attgatgaca tccgatgcaa aaggattgct
     3541 acgtgtcaat ttcaagtctt caaaatcagc tgccgccttc tcagattctt ctggtgtcat
     3601 cagcatcaaa acttggtaga taggctgatt catcaggtga agcaggtcct cttccttttg
     3661 gggaacaacc ttgctgacca tgcgattaaa agactgactc accgtccgag ttaaaacaga
     3721 gggaacgaag cgactaattc gttgggaaaa agaacccaga ccaaaggaca tgattttaga
     3781 acccaacatg gcatccttgg tccctagagc aatctccgtg ccctcttttt tagcatagct
     3841 aattagatgg cgcaaatgta acttggaaat agggctcgtg aacaagactc tgtctttact
     3901 aaagatatac tggccattat aggttaccgc aaaatccaga tccaaatcgt ccatcaattc
     3961 cttaacaaaa aaaggtcctc gtcctgtcgc tacgccaact agtacccctt gttctttgac
     4021 aatcttaatc gcgtccttag tggatttcaa aacactcttg cgattgttga ccaaggttcc
     4081 atcgatatca aaaaaaacag ctttgacttc catcctattc caatctcccc ttttgtgata
     4141 caatgattat accacatttc agaaagagtt agtaaatcat gcctaagaaa atccttgttt
     4201 tacatacggg tggaactatt tccatgcagg ccgatgcttc tggcgctgtt gtgacgagtt
     4261 cagataatcc catgaaccat gtgtccaacc cacttgaagg aatccaagtc cacgccttgg
     4321 acttttttaa ccttccaagt ccccatatca aacccaaaca tatgctggtc ctctaccaga
     4381 aaattaaaga ggaagcagat aactacgatg gagtggtgat cacacacgga accgatactt
     4441 tagaggaaac agcctatttc cttgatacca tggaagttcc ccatatgcct atcgttctaa
     4501 caggagccat gcgtagctcc aatgagctcg gtagtgatgg tgtttataat tacctaagtg
     4561 ctttacgagt ggccagcgat gacagggctg ctgacaaagg agttttggtc gttatgaacg
     4621 atgaaatcca cgctgccaag tatgtcacca aaacacatac gactaatgtc agcaccttcc
     4681 agactccaac acatggcccc ctcggtctca tcatgaaaca ggaaatcctc tacttcaaaa
     4741 cagctgaacc tcgtgttcgc tttgaccttg atcacataca aggtttagtc cctatcatct
     4801 cggcttatgc tggtatgaca gatgagctga ttgatatgct ggatttagaa cacttggacg
     4861 gtttgattat ccaagccttc ggagctggta atattcccaa agaaacggct caaaaattag
     4921 aaagccttct gcaaaaagga atcccagtcg ctctggtatc acgatgcttt aacggtattg
     4981 ccgagcctgt ttatgcctac cagggtgggg gcgtacagtt gcaaaaagca ggcgttttct
     5041 ttgttaaaga actcaacgcc caaaaagctc gcttgaaact cctcatcgcc ctcaatgccg
     5101 gactaacagg acaggctttg aaagactata tggaaggcta atactcttcg aaaatctctg
     5161 caaaccacgt cagcgtcgcc ttaccgtatg tatggtta
//
LOCUS       DAVBOD010000092         5141 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 640-05
            SAMEA1012484-rid20186543.denovo.093, whole genome shotgun sequence.
ACCESSION   DAVBOD010000092 DAVBOD010000000
VERSION     DAVBOD010000092.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012484
            Sequence Read Archive: ERR059358
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5141)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5141)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979948.1
            Genome Coverage       :: 595x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:03:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,266
            CDSs (total)                      :: 2,219
            Genes (coding)                    :: 2,091
            CDSs (with protein)               :: 2,091
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 71 of 128
            Pseudo Genes (incomplete)         :: 50 of 128
            Pseudo Genes (internal stop)      :: 33 of 128
            Pseudo Genes (multiple problems)  :: 22 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5141
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012484-rid20186543.denovo.093"
                     /strain="NIG 640-05"
                     /db_xref="taxon:1313"
     gene            complement(1..117)
                     /locus_tag="VQ862_002053"
                     /pseudo
     CDS             complement(1..117)
                     /locus_tag="VQ862_002053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000370958.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
     gene            complement(121..279)
                     /locus_tag="VQ862_002054"
     CDS             complement(121..279)
                     /locus_tag="VQ862_002054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3116335.1"
                     /translation="MKTVKKEWEPRIVNIMADGSQVDDLTGYVIPAGHSYYDIILGMN
                     KRELQKGA"
     gene            complement(351..1076)
                     /locus_tag="VQ862_002055"
     CDS             complement(351..1076)
                     /locus_tag="VQ862_002055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage antirepressor KilAC domain-containing
                     protein"
                     /protein_id="HET3116336.1"
                     /translation="MNELINVTLNENQEPVVSARQLHQTLEVKKRFSAWFEANSKLFI
                     ENEDFTSVQTGTVVNNGAIKPLQDYALTLDMAKQLAMMSRTIKGAEIRQYFIQVEKDF
                     NSPEKIMARALLMADQKVHKLEAQIEADRPKVLFADAVSASHTSILVSELAKLISQNG
                     YKIGANRLFSWMRENGYLIKRKGSDWNVPTQRSMDLKLFEIMKTNVQHADGHITVNKT
                     PKVTGKGQQYFINKFLNQEYLTG"
     gene            complement(1089..1325)
                     /locus_tag="VQ862_002056"
     CDS             complement(1089..1325)
                     /locus_tag="VQ862_002056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004246378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF739 family protein"
                     /protein_id="HET3116337.1"
                     /translation="MSNDYSKLAGKIVEKYGTQYNFAQAMGLSERSISLKMNNRVPWK
                     DFEMAKASELLDIDVNQLHEYFFTPKVHVREQIA"
     gene            1495..2298
                     /locus_tag="VQ862_002057"
     CDS             1495..2298
                     /locus_tag="VQ862_002057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001149945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HET3116338.1"
                     /translation="MRSSNPSERLKQLMSERNLKQVEILEKSLPYQKELGIKMGKSTL
                     SQYVNGVQSPDQHRIYLLSKTLEVSEPWLMGYDVEKKRIPDSERNSISNEQPEILPIY
                     NKLEEPRQEKVLDFAKKQLEEQKNSKASSIFDKSQDGDDYITDYVEGLVAAGHGTFQE
                     DNLHMEVRLRAEDVPEDYNTIAKVAGDSMEPMIEDNDLLFIKVTNQVDINDIGIFQIN
                     GKNFVKKLKRDYNGGWYLQSLNNSYEEIHLTENDDIRTIGEVVSVYREK"
     gene            2321..3163
                     /locus_tag="VQ862_002058"
     CDS             2321..3163
                     /locus_tag="VQ862_002058"
                     /inference="COORDINATES: protein motif:HMM:NF024098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3800 domain-containing protein"
                     /protein_id="HET3116339.1"
                     /translation="MANWRNRPRNITHISTDIPWIIAIDESGTPDLSYAQRFISPSST
                     NYDPHNVHFNVTACLLSTSIFNETRDMIMDLKNKYWNNAYTNYNNETRRVCFHSTEIR
                     RRKNAFNFQDKATHRLFVDDLSDVLKNINIKLFSSHINKLSLVRQYNTPYDPYELSLT
                     FILERISFETRNQDAVIVLESRGKKEDKKLLNHIVKLLDYGTPYVKKEKFSFIKGVYF
                     NGKWDKQSNNLKSHWILELADLYCYPIFKYGKDGTHDLAFSTLEEKLSGFPNYHGIGI
                     KQFP"
     gene            3694..5139
                     /locus_tag="VQ862_002059"
     CDS             3694..5139
                     /locus_tag="VQ862_002059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HET3116340.1"
                     /translation="MITTNKVAIYVRVSTTNQVEEGYSIDEQKDKLSSYCDIKDWNVY
                     KVYTDGGFSGSNTDRPALESLIKDAKKRKFDTVLVYKLDRLSRSQKDTLHLIEDVFIK
                     NGIEFLSLQENFDTSTPFGKAMIGLLSVFAQLEREQIKERMQLGKLGRAKSGKSMMWA
                     KTSYGYDYHKETGTVTINPSQALTIKFIFESYLRGRSITKLRDDLNEKYPKHVPWSYR
                     AVRTILDNPVYCGFNQYKGEIYPGNHEPIISKEEYDKTQSELKIRQRTAAENVNPRPF
                     QAKYILSGIAQCGYCGAPLKIMLGVKRKDGSRLKKYECHQRHPRTLRGVTTYNDNKKC
                     DSGFYYKDKLEASVLKEISKLQDDADYLDKIFSGDNAETIDRESYKKQIEELSKKLSR
                     LNDLYIDDRITLEELQSKSAEFISMRGTLETELENDPALRKNKRKADMRKLLNAEKVF
                     SMDYENQKVLVRRLINKVKVTAEDIVINWKI"
BASE COUNT         1725 a          978 c          966 g         1472 t
ORIGIN      
        1 ttgattagag agccattctt tgatggctct ttttgaccat ttcttaccag gtaattcctt
       61 tgtaaatccc tttaaataac gataattatc tgaaaatgtg gcatacttaa ttcctaatat
      121 ttaagcccct ttctgtaact ctcgcttgtt catacctaga atgatgtcat agtaggaatg
      181 accagcaggg atgacatatc ctgtcaggtc gtcaacttga gaaccatctg ccatgatgtt
      241 tacaatccgt ggctcccatt ccttttttac tgttttcatg atataattac ctcgtaaagt
      301 attttgctta gtccctcaat ggaattgccg ttccagaggg gcttttgttt ttatcctgtc
      361 aagtattcct gattaaggaa cttattgata aaatactgtt gtcctttgcc tgtgaccttt
      421 ggtgtcttgt tcacagtgat atgtccatct gcgtgttgca cgtttgtttt cataatttca
      481 aagagtttca agtccatgct acgttgggtt ggcacgttcc aatctgatcc tttgcgctta
      541 atcaggtagc cattttcgcg catccaagaa aagaggcgat tggcaccgat tttgtagccg
      601 ttttggctaa tgagcttggc aagttcgcta accaagatag atgtatggct tgcacttact
      661 gcgtctgcaa agaggacttt aggacggtca gcctcaatct gagcctccag cttgtggact
      721 ttctgatcag ccatgagcaa tgctcttgcc ataatcttct caggactgtt gaagtctttt
      781 tctacttgta taaagtattg tcggatctct gctcctttaa tcgtcctaga catcatcgcc
      841 aactgcttag ccatatccaa agttagagca taatcttgta gaggtttgat agctccgtta
      901 tttacaaccg tacccgtttg gacacttgta aaatcttcat tctctataaa taatttagag
      961 tttgcttcaa accaagcgct aaaccttttc ttgacctcta gtgtctgatg taactgccta
     1021 gctgatacta ctggctcctg attctcattc agggttacgt tgatgagttc attcatgtga
     1081 gctcctttct atgctatttg ttcacgaaca tgaactttag gtgtaaaaaa atattcatgt
     1141 aattgattta catcaatatc taacaactct gaggcttttg ccatctcaaa atctttccaa
     1201 ggaactctat tattcatctt taaagagatt gagcgctctg agagccccat tgcttgagca
     1261 aagttgtatt gagtgccata cttttcaaca atctttcctg caagttttga ataatcgtta
     1321 ctcattagct tactcctttc ttgttcattt ttcatgaact attttacaaa acatatttta
     1381 tcacgttgaa tgaacctagt caagtaaaaa attcattttt tatgaacttt ctcttgaatt
     1441 tttgttcaag atggtttata ataggcttat aaacaggaaa aaggaggagg tttcatgagg
     1501 agcagcaacc catctgagcg actaaaacag ctcatgtctg aaagaaattt aaaacaagtt
     1561 gaaatacttg aaaaatcatt accttatcaa aaagaattag gaataaaaat ggggaaaagt
     1621 accctttctc agtatgttaa tggtgtacag tctcctgatc aacacagaat ttacctgctt
     1681 tctaaaacac ttgaagtaag cgaaccttgg cttatgggct atgatgttga gaaaaaacgt
     1741 ataccagata gtgagcgtaa ctcaatatca aatgaacagc ctgaaatctt gccgatctac
     1801 aacaaactag aagaaccaag gcaggagaaa gtccttgact ttgctaaaaa acaactggaa
     1861 gaacaaaaaa attccaaagc tagctctatc tttgacaagt ctcaagatgg cgatgactac
     1921 attactgatt acgtagaagg cttggttgca gcaggacatg gaacgtttca ggaagacaac
     1981 ctccacatgg aagtaagact gcgtgccgaa gatgtccctg aagactacaa cactatcgct
     2041 aaggtggctg gtgactccat ggaaccaatg attgaagata acgacctgct ctttatcaaa
     2101 gtcacgaatc aggtagatat caacgacatc ggcattttcc aaatcaatgg taaaaacttt
     2161 gttaaaaagc tgaaacgtga ttataacggc ggttggtact tgcaaagcct caacaatagc
     2221 tatgaagaaa tccacctgac agagaatgac gacatccgaa ctattgggga ggttgtcagt
     2281 gtgtataggg agaaataaaa atagagagga aaactaaata atggcaaatt ggagaaacag
     2341 accaagaaat attacacata ttagcactga catcccatgg ataatagcaa ttgatgagag
     2401 cggtactccc gacttaagct acgctcaacg ctttatctcc ccttcatcaa caaactatga
     2461 tccacacaat gttcacttca atgtcactgc ttgtctcttg tcaacaagta ttttcaatga
     2521 aactagagac atgataatgg atttaaaaaa taaatattgg aataatgctt atactaacta
     2581 taacaacgaa acaagacgag tatgttttca ttctacggaa attagaagac gaaaaaatgc
     2641 gtttaatttt caagataaag caacccaccg tctttttgta gacgatttat cggatgtcct
     2701 caaaaacata aatatcaaat tattctcatc ccacataaat aagttgagtt tggttagaca
     2761 atataatact ccatacgatc cttatgaatt atcactaact tttatcttgg agcgtatttc
     2821 gtttgaaacg agaaatcaag acgctgtaat cgttttagaa tctagaggaa aaaaagaaga
     2881 taaaaaatta ttaaaccaca ttgtaaaact acttgattat ggcacaccgt atgtaaaaaa
     2941 agaaaaattt tcttttataa aaggagtgta ctttaacggt aaatgggata aacaatcgaa
     3001 taatttaaaa tcccattgga ttttagaatt agcagatctt tactgctacc ctattttcaa
     3061 gtacggcaaa gacggaacac atgatttagc ctttagtact ttagaagaaa aattatctgg
     3121 tttcccaaat tatcacggaa taggtattaa acaattccct taaaaatcaa aaaaaacacc
     3181 cgccaaaagc gagtgttccg tccgcacact tacgaacccc aaagagtcat taactcttaa
     3241 cttaattata cactatcttc accattataa caaataaaaa gttttgtttg ttaagaaaat
     3301 taataaacca ttttggaaac aactcaaaaa atccccccac tctccgacag ccatctttga
     3361 gtgtgaggat atcctgtata gtaatcggac gcaattagcg aacggattat atttgacaac
     3421 taaatagaaa ttttgataaa atacagttgg attacctaga tgataccatc tagtgcaaaa
     3481 tacggcaggt agctcctgcc tcggtcacag ctgtacaata attgtgcagc ttttttgatt
     3541 acacaaacaa aaaagcccca cgctctcaaa gttggtagct ctgagcgtga ggctagcaat
     3601 tacaagaaaa acttttcaaa agatattacc ttttgagatg ttttcttgta cccattttat
     3661 cattttttag gaaattttga aagaggtact actatgataa caacaaataa agtagctata
     3721 tatgtcaggg tatcgacgac aaaccaggtt gaggagggat actctataga tgagcaaaaa
     3781 gacaagctct ctagctactg cgacattaaa gactggaatg tatacaaagt atatactgat
     3841 ggaggtttct caggatccaa tactgacaga ccagcgctag aaagtcttat caaagacgct
     3901 aaaaaaagaa aatttgacac agttctagtc tataagctgg accgtcttag ccgtagtcaa
     3961 aaagacacgc ttcacttgat tgaggatgta ttcatcaaga atgggattga atttctgagc
     4021 ttgcaggaga actttgacac ctctactcct tttggtaagg ctatgattgg actcttgagc
     4081 gtctttgctc agctagaaag ggagcaaatc aaggaacgca tgcaacttgg caagctagga
     4141 cgtgccaaat ctggtaaatc catgatgtgg gctaagacat cctatggtta cgattaccac
     4201 aaagagacag gcacagtgac catcaatcca tctcaggctc tgaccattaa gtttatcttt
     4261 gagagttacc tgagagggag atctattact aagttgagag atgatctaaa tgagaaatac
     4321 ccaaagcatg tgccttggag ctatcgggcg gtcagaacca tactcgataa ccctgtctat
     4381 tgtggtttca atcagtataa gggagaaatt tatccaggta atcatgagcc gattatttca
     4441 aaagaggaat acgataagac tcaatctgag ctaaaaataa gacaaagaac agcagcagag
     4501 aatgtcaatc ctagaccatt ccaagctaag tacattttat ccggtatcgc ccaatgtgga
     4561 tattgtggcg ctcctttaaa aattatgtta ggcgtaaaga ggaaagatgg gagcaggtta
     4621 aaaaaatatg aatgccacca aaggcaccca cgaacgctga gaggcgttac tacctacaac
     4681 gacaataaaa agtgtgactc aggattttac tacaaagaca agctagaggc ctctgtgcta
     4741 aaagaaataa gcaaactaca agatgacgct gattacctgg acaaaatatt ttcaggagac
     4801 aatgctgaga ccatagaccg tgagagctat aagaaacaaa tagaggagct atcaaagaaa
     4861 ctgagcagac ttaacgatct atacatagat gaccgcatta cccttgaaga attacagagc
     4921 aagtcagccg aatttataag catgaggggg actcttgaaa ctgaactaga aaacgatcca
     4981 gcactcagga agaacaaaag aaaggctgat atgaggaaac tgctaaacgc tgagaaagtc
     5041 ttttcaatgg actacgaaaa tcaaaaggtg cttgttagaa ggcttataaa caaggttaag
     5101 gtgacagctg aggacattgt tatcaattgg aaaatataaa t
//
LOCUS       DAVBOD010000093         4949 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 640-05
            SAMEA1012484-rid20186543.denovo.094, whole genome shotgun sequence.
ACCESSION   DAVBOD010000093 DAVBOD010000000
VERSION     DAVBOD010000093.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012484
            Sequence Read Archive: ERR059358
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4949)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4949)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979948.1
            Genome Coverage       :: 595x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:03:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,266
            CDSs (total)                      :: 2,219
            Genes (coding)                    :: 2,091
            CDSs (with protein)               :: 2,091
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 71 of 128
            Pseudo Genes (incomplete)         :: 50 of 128
            Pseudo Genes (internal stop)      :: 33 of 128
            Pseudo Genes (multiple problems)  :: 22 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4949
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012484-rid20186543.denovo.094"
                     /strain="NIG 640-05"
                     /db_xref="taxon:1313"
     gene            251..1796
                     /locus_tag="VQ862_002060"
     rRNA            251..1796
                     /locus_tag="VQ862_002060"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
     gene            1848..1920
                     /locus_tag="VQ862_002061"
     tRNA            1848..1920
                     /locus_tag="VQ862_002061"
                     /product="tRNA-Ala"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1881..1883,aa:Ala,seq:tgc)
     gene            2045..4946
                     /locus_tag="VQ862_002062"
     rRNA            2045..4946
                     /locus_tag="VQ862_002062"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT         1399 a         1003 c         1455 g         1092 t
ORIGIN      
        1 gtatgttgcg gttggaacac ttgatgaaaa aaagtttaaa aaagcttaaa aatcttcaaa
       61 aaagtgttga caagcgaaag cggctgtgat atactaatat agttgtcgct tgagagaagc
      121 gagtgacaaa gacctttgaa aactgaacaa gacgaaccaa tgtgcagggc gctacaacat
      181 aagttgtagt actgaacaat gaaaaaaaca ataaatctgt cagtgacaga aatgagtgag
      241 aactcaaact tttaatgaga gtttgatcct ggctcaggac gaacgctggc ggcgtgccta
      301 atacatgcaa gtagaacgct gaaggaggag cttgcttctc tggatgagtt gcgaacgggt
      361 gagtaacgcg taggtaacct gcctggtagc gggggataac tattggaaac gatagctaat
      421 accgcataag agtagatgtt gcatgacatt tgcttaaaag gtgcacttgc atcactacca
      481 gatggacctg cgttgtatta gctagttggt ggggtaacgg ctcaccaagg cgacgataca
      541 tagccgacct gagagggtga tcggccacac tgggactgag acacggccca gactcctacg
      601 ggaggcagca gtagggaatc ttcggcaatg gacggaagtc tgaccgagca acgccgcgtg
      661 agtgaagaag gttttcggat cgtaaagctc tgttgtaaga gaagaacgag tgtgagagtg
      721 gaaagttcac actgtgacgg tatcttacca gaaagggacg gctaactacg tgccagcagc
      781 cgcggtaata cgtaggtccc gagcgttgtc cggatttatt gggcgtaaag cgagcgcagg
      841 cggttagata agtctgaagt taaaggctgt ggcttaacca tagtaggctt tggaaactgt
      901 ttaacttgag tgcaagaggg gagagtggaa ttccatgtgt agcggtgaaa tgcgtagata
      961 tatggaggaa caccggtggc gaaagcggct ctctggcttg taactgacgc tgaggctcga
     1021 aagcgtgggg agcaaacagg attagatacc ctggtagtcc acgctgtaaa cgatgagtgc
     1081 taggtgttag accctttccg gggtttagtg ccgtagctaa cgcattaagc actccgcctg
     1141 gggagtacga ccgcaaggtt gaaactcaaa ggaattgacg ggggcccgca caagcggtgg
     1201 agcatgtggt ttaattcgaa gcaacgcgaa gaaccttacc aggtcttgac atccctctga
     1261 cgactctaga gatagagttt tccttcggga cagaggtgac aggtggtgca tggttgtcgt
     1321 cagctcgtgt cgtgagatgt tgggttaagt cccgcaacga gcgcaacccc tattgttagt
     1381 tgccatcatt tagttgggca ctctagcgag actgccggta ataaaccgga ggaaggtggg
     1441 gatgacgtca aatcatcatg ccccttatga cctgggctac acacgtgcta caatggctgg
     1501 tacaacgagt cgcaagccgg tgacggcaag ctaatctctt aaagccagtc tcagttcgga
     1561 ttgtaggctg caactcgcct acatgaagtc ggaatcgcta gtaatcgcgg atcagcacgc
     1621 cgcggtgaat acgttcccgg gccttgtaca caccgcccgt cacaccacga gagtttgtaa
     1681 cacccgaagt cggtgaggta accgtaagga gccagccgcc taaggtggga tagatgattg
     1741 gggtgaagtc gtaacaaggt agccgtatcg gaaggtgcgg ctggatcacc tcctttctaa
     1801 ggataaggaa ctgcgcattg gtcttgttta gtcttgagag gtcttgtggg gccttagctc
     1861 agctgggaga gcgcctgctt tgcacgcagg aggtcagcgg ttcgatcccg ctaggctcca
     1921 ttggtgagag atcaccaagt aatgcacatt gaaaattgaa tatctatatc aaatagtaac
     1981 aagaaaataa accgaaaacg ctgtagtatt aataagagtt tatgactgaa aggtcagaaa
     2041 ataaggttaa gttaataagg gcgcacggtg gatgccttgg cactaggagc cgacgaagga
     2101 cgtgacaaac gacgatatgc cttgggtagc tgtaagtaag cgatgatcca tggatttccg
     2161 aatgggggaa cccaacaggt aatacctgtt acccacatct gttaaggatg tgaggaggaa
     2221 gacgcagtga actgaaacat ctaagtagct gcaggaagag aaagcaaaag cgattgcctt
     2281 agtagcggcg agcgaaacgg cagaagggca aaccgaagag tttactcttc ggggttgtag
     2341 gactgcaatg tggactcaaa gattatagaa gaatgatttg ggaagatcag ccaaagagag
     2401 taatagcctc gtatttaaaa tagtctttgt acctagcagt atcctgagta cggcgggaca
     2461 cgtgaaatcc cgtcggaatc tgggaggacc atctcccaac cctaaatact ccctagtgac
     2521 cgatagtgaa ccagtaccgt gagggaaagg tgaaaagcac cccgggaggg gagtgaaata
     2581 gaacctgaaa ccgtgtgcct acaacaagtt cgagcccgtt aatgggtgag agcgtgcctt
     2641 ttgtagaatg aaccggcgag ttacgttatg atgcgaggtt aagttgaaga gacggagccg
     2701 tagggaaacc gagtctgaat agggcgcctt agtatcatga cgtagacccg aaaccatgtg
     2761 acctacccat gagcaggttg aaggtgcggt aagacgcact ggaggaccga accagggcac
     2821 gttgaaaagt gcttggatga cttgtgggta gcggagaaat tccaaacgaa cttggagata
     2881 gctggttctc tccgaaatag ctttagggct agcgtcgaca ttagagattc ttggaggtag
     2941 agcactgttt gggtgagggg tccatcccgg attaccaatc tcagataaac tccgaatgcc
     3001 aatgaattat ggtcggcagt cagactgcga gtgctaagat ccgtagtcga aagggaaaca
     3061 gcccagacca ccagctaagg tcccaaaata attgttaagt ggaaaaggat gtggggttgc
     3121 acagacaact aggatgttag cttagaagca gctattcatt caaagagtgc gtaatagctc
     3181 actagtcgag tgaccctgcg ccgaaaatgt accggggcta aaacaattta ccgaagctgt
     3241 ggataccttt ataggtatgg taggagagcg ttctatgtgt gatgaaggta taccgtgagg
     3301 agtgctggaa cgcatagaag tgagaatgcc ggtatgagta gcgaaagaca ggtgagaatc
     3361 ctgtccaccg taagactaag gtttccaggg gaaggctcgt ccgccctggg ttagtcggga
     3421 cctaaggaga gaccgaaagg tgtatccgat ggacaacagg ttgatattcc tgtactagag
     3481 tatgtagtga tggagggacg cagtaggcta actaaagcag acgattggaa gagtctgtct
     3541 aagcagtgag gtgtgaattg agtcaaatgc ttaattctat aacattgagc tgtgatgggg
     3601 agcgaagttt agtagcgaag ttagtgacgt cacactgcca agaaaagctt ctagcgttta
     3661 aacatactct acccgtaccg caaaccgaca caggtagtcg aggcgagtag cctcaggtga
     3721 gcgagagaac tctcgttaag gaactcggca aaatgacccc gtaacttcgg gagaaggggt
     3781 gctgacttta agtcagccgc agtgaatagg cccaagcaac tgtttatcaa aaacacagct
     3841 ctctgctaaa tcgtaagatg atgtataggg ggtgacgcct gcccggtgct ggaaggttaa
     3901 gaggagtgct tagcgtaagc gaaggtatga attgaagccc cagtaaacgg cggccgtaac
     3961 tataacggtc ctaaggtagc gaaattcctt gtcgggtaag ttccgacccg cacgaaaggc
     4021 gtaatgattt gggcactgtc tcaacgagag actcggtgaa attttagtac ctgtgaagat
     4081 gcaggttacc cgcgacagga cggaaagacc ccatggagct ttactgcagt ttgatattga
     4141 gtgtctgtac cacatgtaca ggataggtag gagtctaaga gatcgggacg ccagtttcga
     4201 aggagacgct gttgggatac tacccttgtg ttatggccac tctaacccag ataggtgatc
     4261 cctatcggag acagtgtctg acgggcagtt tgactggggc ggtcgcctcc taaaaggtaa
     4321 cggaggcgcc caaaggttcc ctcagaatgg ttggaaatca ttcgcagagt gtaaaggtat
     4381 aagggagctt gactgcgaga gctacaactc gagcagggac gaaagtcggg cttagtgatc
     4441 cggtggttcc gtatggaagg gccatcgctc aacggataaa agctaccctg gggataacag
     4501 gcttatctcc cccaagagtt cacatcgacg gggaggtttg gcacctcgat gtcggctcgt
     4561 cgcatcctgg ggctgtagtc ggtcccaagg gttgggctgt tcgcccatta aagcggcacg
     4621 cgagctgggt tcagaacgtc gtgagacagt tcggtcccta tccgtcgcgg gcgtaggaaa
     4681 tttgagagga tctgctccta gtacgagagg accagagtgg acttaccgct ggtgtaccag
     4741 ttgtcttgcc aaaggcatcg ctgggtagct atgtagggaa gggataaacg ctgaaagcat
     4801 ctaagtgtga aacccacctc aagatgagat ttcccatgat tatatatcag taagagccct
     4861 gagagatgat caggtagata ggttagaagt ggaagtgtgg cgacacatgt agcggactaa
     4921 tactaatagc tcgaggactt atccaaagt
//
LOCUS       DAVBOD010000094         4587 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 640-05
            SAMEA1012484-rid20186543.denovo.095, whole genome shotgun sequence.
ACCESSION   DAVBOD010000094 DAVBOD010000000
VERSION     DAVBOD010000094.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012484
            Sequence Read Archive: ERR059358
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4587)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4587)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979948.1
            Genome Coverage       :: 595x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:03:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,266
            CDSs (total)                      :: 2,219
            Genes (coding)                    :: 2,091
            CDSs (with protein)               :: 2,091
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 71 of 128
            Pseudo Genes (incomplete)         :: 50 of 128
            Pseudo Genes (internal stop)      :: 33 of 128
            Pseudo Genes (multiple problems)  :: 22 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4587
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012484-rid20186543.denovo.095"
                     /strain="NIG 640-05"
                     /db_xref="taxon:1313"
     gene            complement(80..517)
                     /locus_tag="VQ862_002063"
     CDS             complement(80..517)
                     /locus_tag="VQ862_002063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-binding protein"
                     /protein_id="HET3116341.1"
                     /translation="MSQEFINPSDGVIRQYLATSKTLAVVGLSDREETTSNRVTKEMQ
                     ARGYKIIPVNPKAAGGEILGEKAYASLAEIPFPVDIVNVYRRSEFLPDVARDFLKADA
                     KIFWAQLGLESLKAKEILRDGGCDDIVMNRCIKREHTRLIEEA"
     gene            complement(602..3235)
                     /gene="polA"
                     /locus_tag="VQ862_002064"
     CDS             complement(602..3235)
                     /gene="polA"
                     /locus_tag="VQ862_002064"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014932012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase I"
                     /protein_id="HET3116342.1"
                     /translation="MDKKKLLLIDGSSVAFRAFFALYQQLDRFKNAAGLHTNAIYGFQ
                     LMLSHLLERVEPSHILVAFDAGKTTFRTEMYADYKGGRAKTPDEFREQFPFIRELLDH
                     MGIRHYELAQYEADDIIGTLDKLAEQDGFDITIVSGDKDLIQLTDEHTVVEISKKGVA
                     EFEAFTPDYLMEEMGLTPAQFIDLKALMGDKSDNIPGVTKVGEKTGIKLLLEHGSLEG
                     IYENIDGMKTSKMKENLINDKEQAFLSKTLATIDTKAPIAIGLEDLVYSGPDVENLGK
                     FYDEMGFKQLKQALNVSSADVSESLDFTIVDQISQDMLSEESIFHFELFGENYHTDNL
                     VGFAWSCGDKLYATDKLELLQDPIFKDFLEKTSLRVYDFKKVKVLLQRFGVDLQAPAF
                     DIRLVKYLLSTVEDNEIATIASLYGQTYLVDDETFYGKGVKKAIPEREKFLEHLACKL
                     AVLVETEPILLEKLSENGQLELLYDMEQPLAFVLAKMEIAGIMVKKETLLEMQAENEL
                     VIEKLTQEIYELAGEEFNVNSPKQLGVLLFEKLGLPLEYTKKTKTGYSTAVDVLERLA
                     PIAPIVKKILDYRQIAKIQSTYVIGLQDWILADGKIHTRYMQDLTQTGRLSSVDPNLQ
                     NIPARLEQGRLIRKAFVPEWEDSVLLSSDYSQIELRVLAHISKDEHLIKAFQEGADIH
                     TSTAMRVFGIERPDNVTANDRRNAKAVNFGVVYGISDFGLSNNLGISRKEAKAYIDTY
                     FERFPGIKNYMDEVVREARDKGYVETLFKRRRELPDINSRNFNIRGFAERTAINSPIQ
                     GSAADILKIAMIQLDKALVAGGYQTKMLLQVHDEIVLEVPKSELVEMKKLVKQTMEEA
                     IQLSVPLIADENEGATWYEAK"
     gene            3491..3841
                     /locus_tag="VQ862_002065"
     CDS             3491..3841
                     /locus_tag="VQ862_002065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001811778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family transposase"
                     /protein_id="HET3116343.1"
                     /translation="MLRHPGISPTNDLIAKKIFSNPEITCQFIRDMLDLPAKNVTILE
                     GSDIHVLLSMPYSVQDFYTSIDVLAELDNGTQVIIEIQVHHQNFFINHLWAYLCSQVN
                     QNLEKIRQREGDTH"
     gene            4056..4160
                     /locus_tag="VQ862_002066"
     CDS             4056..4160
                     /locus_tag="VQ862_002066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000233180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="damage-inducible protein CinA"
                     /protein_id="HET3116344.1"
                     /translation="MVGVFRQQALYPATATSHYPSKSTAGLQELVRGG"
     gene            4165..4398
                     /locus_tag="VQ862_002067"
     CDS             4165..4398
                     /locus_tag="VQ862_002067"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3116345.1"
                     /translation="MFSQLRMREEQALLAQDYALETARAGGIEQGLERGKVEGREERK
                     LFAFLDIVRQDLLTSEVASQQLGMSVSEFEALL"
BASE COUNT         1400 a         1091 c          845 g         1251 t
ORIGIN      
        1 gcccgcggct agtttcctag tttgctcttt gattttcatt gagtataaca caaaaggtag
       61 cccatcagct acctttttct tatgcttcct caatcaagcg agtatgttct ctcttgatac
      121 agcgattcat cacgatatca tcacatccac catcacgcaa aatctctttc gcttttaaac
      181 tttcaagtcc tagctgtgcc caaaaaatct tggcatcagc tttgagaaaa tcacgcgcca
      241 catcgggcag aaattcactg cgacgataaa cattgacaat atctacagga aaaggaattt
      301 cagcgaggct agcataagcc ttttcaccca agatttcgcc acctgccgcc ttgggattga
      361 ctgggatgat tttatagccc cgagcctgca tttcctttgt cactcgattg ctggttgttt
      421 cttcacggtc agacaaaccc accacagcaa gggttttact cgttgcgaga tactgacgaa
      481 tcacgccatc acttggattg ataaattctt gactcataga aaacctcctt tttcatcagt
      541 atagcacatt ttgaaaaggt ttgcagaatt ctactacaaa aaaggaggac tagccccctt
      601 tttatttagc ctcgtaccag gttgcccctt cattctcatc tgcgataaga ggaacactga
      661 gttgaatggc ttcttccatg gtttgtttca ccaatttttt catctctacc aattcagatt
      721 taggcacttc aaggacgatt tcatcgtgca cttgtaacag catcttagtc tgataaccac
      781 ctgcaaccaa ggctttatcc agctgaatca tggcaatctt gagaatatct gctgccgaac
      841 cctggatagg tgagttgata gcagttcgct ccgcaaaacc acgaatattg aagttgcgcg
      901 aattgatatc tggcaactca cggcgacgct taaagagggt ctctacatag cccttatcac
      961 gcgcctcccg caccacttca tccatgtagt ttttaatacc tggaaaacgt tcaaagtagg
     1021 tatcaatgta ggctttggct tccttacgac taattcccaa attattagac aagccaaagt
     1081 ctgaaatccc ataaaccact ccaaagttaa ctgccttggc attgcgacga tcatttgcag
     1141 tcacattatc aggacgctca atgccaaaga cccgcatggc tgtcgaagta tggatatctg
     1201 ccccctcttg gaaggcctta atcaagtgct catccttaga aatatgcgcc aaaacgcgca
     1261 attcaatctg tgaatagtca gagctgagta gcacactatc ctcccactct ggcacaaaag
     1321 ccttccgaat caagcgccct tgttccaatc gggcaggaat attttgcaag tttggatcca
     1381 cactagacaa acgcccggtc tgggtcaaat cctgcatata gcgagtatga atctttccat
     1441 cagccaaaat ccagtcctgc aagccaatta cataagtaga ttgaatctta gcaatttgac
     1501 ggtaatccag gattttctta acaatcggag caataggagc gagacgctcc aacacatcca
     1561 ctgctgtcga ataacctgtc ttggttttct tagtgtattc tagaggaagt cccaatttct
     1621 caaagagaag cacgcccaac tgcttaggcg agttgacatt aaactcctca ccagccagct
     1681 cgtaaatctc ttgagtcagt ttttcaatga caagctcatt ttcagcctgc atctcaagca
     1741 aggtctcttt cttgaccata atcccagcaa tttccatctt ggcaaggaca aaagccagag
     1801 gttgctccat atcataaaga agctctaatt gcccattttc gctgagtttt tcaagtaaaa
     1861 taggctctgt ttctaccaaa acagcaagtt tacaagctaa gtgttccaag aatttctcac
     1921 gttcaggaat ggccttttta acacccttac cgtagaaagt ttcatcatca accaagtaag
     1981 tctgaccata aagactagcg atggtcgcaa tttcattgtc ctccacagtc gaaaggaggt
     2041 atttaaccaa acggatgtca aaagcaggcg cctgcaaatc cacaccaaaa cgttgcaaaa
     2101 gaactttaac cttcttaaag tcataaactc tcagagatgt tttttctaag aaatccttga
     2161 aaatcgggtc ttgcaacagc tcaagcttgt ctgtggcata gagcttatcc ccacaagacc
     2221 aggcaaatcc aaccaaatta tccgtatggt aattctcacc aaaaagctca aagtggaaga
     2281 tagactcttc actcagcata tcttgactga tttggtcaac aatagtaaaa tccaaactct
     2341 cagacacatc agctgacgac acatttaaag cctgctttag ctgtttgaag cccatctcat
     2401 cgtagaattt cccaagattt tcaacatctg gaccactata gaccaagtcc tctaaaccaa
     2461 tcgcaatcgg tgccttggta tcaatggtcg ctagtgtttt agataaaaag gcctgttcct
     2521 tgtcattgat gagattttcc ttcatcttag aagtcttcat tccatcaata ttttcataaa
     2581 tcccctcaag cgaaccatgc tccagcaaga gcttaatacc cgtcttttca ccgactttgg
     2641 tcaccccagg gatattatcc gacttatcac ccatgagcgc cttgagatcg ataaactgag
     2701 ctggtgtgag gcccatttct tccatgaggt aatctggcgt aaaggcctca aactcagcca
     2761 cacctttctt ggaaatttca accaccgtat gctcatccgt cagctgaatc aaatccttgt
     2821 ccccactgac aatggtaata tcaaaaccat cctgctctgc tagcttatcc agcgtcccaa
     2881 tgatgtcatc cgcctcatac tgagccagct catagtgacg aatccccata tgatccagca
     2941 actcacgaat gaaaggaaat tgctcacgaa actcatcagg agtcttggcc cgaccaccct
     3001 tatagtccgc atacatctct gtccggaagg tcgtctttcc cgcatcaaaa gccaccaaaa
     3061 tatgactcgg ctcaacccgc tccaacaaat gactcaacat caactgaaaa ccataaatcg
     3121 cattggtatg caaaccagcc gcattcttaa aacggtccaa ctgctgatac agcgcaaaaa
     3181 acgcccgaaa agctacagaa gacccatcaa tcaataataa ttttttctta tccatacacc
     3241 cattataaag gaaagaatca aaaaatacca ttgggaagag ctagagcaag tatttttcaa
     3301 actttttccg aataaataga tagagccaga gaatttagta aacctagatt taaaaatgtg
     3361 ctataatata gtatattgaa tctataatag tacaccttga ctgctaaaat atttctataa
     3421 attaatttga ctttcctgat agagttattc acatcttatt tcaactcact atagaaggag
     3481 gaataggagg attctcagac atccgggcat cagcccaact aatgatttga ttgctaagaa
     3541 aatattcagc aatccagaaa tcacttgtca atttattcgc gatatgctgg acttgccagc
     3601 aaaaaatgtg accattttgg agggaagcga tattcacgta ttactctcca tgccttactc
     3661 ggtgcaggat ttttatacca gtatagacgt cttggcggag ttggataacg gtactcaagt
     3721 aattattgag attcaagtcc atcatcagaa ttttttcatc aatcacttgt gggcttacct
     3781 gtgcagtcag gttaatcaaa atcttgaaaa aattcgtcag cgagaaggtg atactcacta
     3841 gatctacaaa cacatcgctc ctgtttacgt cattgctatc gtggatagta attatttctc
     3901 agatgacctg gcttttcata gctttagtat gcgcgaagac acaacaggtg aggtattggc
     3961 gattaccaac aatggacagg aaaaccatct ggttaagatg gcattcttgg aattaaaaaa
     4021 tacagagaaa ccagcaaaga caaggttcgc aagccatggt tggagttttt cggcaacaag
     4081 ccctttaccc agcaaccgca acgagccatt acccaagcaa atcaactgct ggactacaag
     4141 agctggtccg aggaggatag gaaaatgttt agtcaactac gtatgcgaga agaacaagcc
     4201 ttgttagcgc aggactatgc cttggaaact gctagggcgg gaggtattga acaaggctta
     4261 gagcgtggga aagttgaagg aagggaagaa aggaaacttt ttgccttcct agacatagta
     4321 cgccaagatc ttctgacttc tgaggttgcc agccagcaat taggtatgtc agtatctgaa
     4381 tttgaggcac tgttgtaaaa tggctccata atatccatag tgggtaaatc ccctatggat
     4441 attatggagc ctattttgtg tagaaaaaaa gtcccatatg acctataatg aaaagcgaca
     4501 aaacaactca ttagaaagaa tcatatggaa caattacatt ttatcacaaa attactagac
     4561 attaaagacc ctaatgtcca gatttta
//
LOCUS       DAVBOD010000095         4535 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 640-05
            SAMEA1012484-rid20186543.denovo.096, whole genome shotgun sequence.
ACCESSION   DAVBOD010000095 DAVBOD010000000
VERSION     DAVBOD010000095.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012484
            Sequence Read Archive: ERR059358
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4535)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4535)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979948.1
            Genome Coverage       :: 595x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:03:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,266
            CDSs (total)                      :: 2,219
            Genes (coding)                    :: 2,091
            CDSs (with protein)               :: 2,091
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 71 of 128
            Pseudo Genes (incomplete)         :: 50 of 128
            Pseudo Genes (internal stop)      :: 33 of 128
            Pseudo Genes (multiple problems)  :: 22 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4535
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012484-rid20186543.denovo.096"
                     /strain="NIG 640-05"
                     /db_xref="taxon:1313"
     gene            <1..287
                     /locus_tag="VQ862_002068"
     CDS             <1..287
                     /locus_tag="VQ862_002068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000458188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
                     /protein_id="HET3116346.1"
                     /translation="QYNGSWYYLNANGAMATGWAKVNGSWYYLNANGSMATGWVKDGD
                     TWYYLEASGAMKASQWFKVSDKWYYVNGLGALAVNTTVDGYEVNANGEWV"
     gene            688..1809
                     /gene="mnmA"
                     /locus_tag="VQ862_002069"
     CDS             688..1809
                     /gene="mnmA"
                     /locus_tag="VQ862_002069"
                     /EC_number="2.8.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiouridine(34) synthase MnmA"
                     /protein_id="HET3116347.1"
                     /translation="MSDNSKTRVVVGMSGGVDSSVTALLLKEQGYDVIGIFMKNWDDT
                     DENGVCTATEDYKDVVAVADQIGIPYYSVNFEKEYWDRVFEYFLAEYRAGRTPNPDVM
                     CNKEIKFKAFLDYAMTLGADYVATGHYARVARDEDGTVHMLRGVDNGKDQTYFLSQLS
                     QEQLQKTMFPLGHLEKPEVRKLAEEAGLSTAKKKDSTGICFIGEKNFKNFLSNYLPAQ
                     PGRMMTVDGRDMGEHAGLMYYTIGQRGGLGIGGQHGGDNAPWFVVGKDLSKNILYVGQ
                     GFYHDSLMSTSLEASQVHFTREMPEEFTLECTAKFRYRQPDSKVTVHVKGDKAEVIFA
                     EPQRAITPGQAVVFYDGEECLGGGLIDNAYRDGQVCQYI"
     gene            1950..2405
                     /locus_tag="VQ862_002070"
     CDS             1950..2405
                     /locus_tag="VQ862_002070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HET3116348.1"
                     /translation="MTQQDFRTKVDNTVFGVRATALILQNHKLLVTKDKGKYYTIGGA
                     IQVNESTEDAVVREVKEELGVKAQAGQLAFVVENRFEQDGVSYHNIEFHYLVDLLEDA
                     PLTMQEDEKRQPCEWIDLDKLEDIQLVPAFLKTALPDWEGQLRHIHLEE"
     gene            2415..4328
                     /gene="mnmG"
                     /locus_tag="VQ862_002071"
     CDS             2415..4328
                     /gene="mnmG"
                     /locus_tag="VQ862_002071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis enzyme MnmG"
                     /protein_id="HET3116349.1"
                     /translation="MTYHFTEEYDIIVIGAGHAGVEASLAASRMGCKVLLATINIEML
                     AFMPCNPSIGGSAKGIVVREVDALGGEMAKTIDKTYIQMKMLNTGKGPAVRALRAQAD
                     KELYSKEMRKTVENQENLTLRQTMIDEILVEDGKVVGVRTATHQEYAAKAVIVTTGTA
                     LRGEIIIGDLKYSSGPNHSLASINLADNLKELGLEIGRFKTGTPPRVKASSINYDVTE
                     IQPGDEVPNHFSYTSRDEDYVKDQVPCWLTYTNGTSHEIIQNNLHRAPMFTGVVKGVG
                     PRYCPSIEDKIVRFADKERHQLFLEPEGRNTEEVYVQGLSTSLPEDVQRDLVHSIKGL
                     ENAEMMRTGYAIEYDMVLPHQLRATLETKKISGLFTAGQTNGTSGYEEAAGQGIIAGI
                     NAALKIQGKPELILKRSDGYIGVMIDDLVTKGTIEPYRLLTSRAEYRLILRHDNADMR
                     LTEMGREIGLVDDERWARFEIKKNQFDNEMKRLDSIKLKPVKETNAKVEEMGFKPLTD
                     AVTAKEFLRRPEVSYQDVVAFIGPAAEDLDDKIIELIETEIKYEGYISKAMDQVAKMK
                     RMEEKRIPANIDWDDIDSIATEARQKFKLINPETIGQASRISGVNPADISILMVYLEG
                     KNRSISKTLQKSK"
BASE COUNT         1310 a          921 c         1105 g         1199 t
ORIGIN      
        1 tccaatacaa cggttcatgg tactacctaa acgctaacgg tgctatggca acaggttggg
       61 ctaaagtcaa cggttcatgg tactacctca acgctaacgg ttcaatggca acaggttggg
      121 tgaaagatgg agatacctgg tactatcttg aagcatcagg tgctatgaaa gcaagccaat
      181 ggttcaaagt atcagataaa tggtactatg tcaatggctt aggtgccctt gcagtcaaca
      241 caactgtaga tggctatgaa gtcaatgcca atggtgaatg ggtttaagcc gattaaatta
      301 aatcatgtta agaacatttg acattttaat tttgaaacaa agataaggtt cgattgaata
      361 aatttatgtt cgtattcttt aggtacctat cttatgattt caggaaatgt cattaaaaaa
      421 acgactcctt ttctctaact tgaaaaatag attagagaaa atgggttgtt ttatttatta
      481 tagttatttg aatgaagata agaagaaggt atactcacat cattcacata atctgtatat
      541 tgactataag ttttaaaaaa caatttttaa gctcttcctt gtcttctcta accaagcgtg
      601 ttataatgaa tactgctcaa gcgaccttca atcgtgaagc acacacgacc ttcaatcgtg
      661 aataaacgaa tagatgggag acttaccatg agtgataact ctaaaacacg tgttgtcgtg
      721 gggatgagtg gtggtgttga ttcgtcggtg acggctcttt tgctcaagga gcagggctac
      781 gatgtgatcg gtatcttcat gaagaactgg gatgacacag atgaaaacgg cgtctgtacg
      841 gcgaccgaag attacaagga tgtggttgcg gtggcagacc agattggcat tccctactac
      901 tctgtcaatt ttgaaaaaga gtactgggac cgcgtttttg agtatttcct agcggaatac
      961 cgtgcagggc gcacgccaaa tccggacgtt atgtgcaaca aggaaatcaa gttcaaggcc
     1021 tttttggact atgccatgac cttgggggca gactatgtag cgactgggca ttatgctcga
     1081 gtggcgcgtg atgaggacgg cactgttcac atgcttcgtg gcgtggacaa tggcaaggac
     1141 cagacctatt tcctcagcca actttcgcaa gaacaacttc aaaaaaccat gttcccacta
     1201 ggacatttgg aaaagcctga agttcgaaaa ctagcagaag aagcaggcct ttcgactgct
     1261 aagaagaaag actcgacagg gatttgcttt atcggagaaa agaactttaa aaacttcctc
     1321 agcaactacc tgccagctca gcctggtcgc atgatgactg tggatggtcg cgatatgggc
     1381 gagcatgcag gtctgatgta ttatacaatc ggtcagcgtg gcggactcgg tatcggtggg
     1441 caacacggcg gtgacaatgc cccttggttc gttgtcggaa aagatctaag caagaatatt
     1501 ctctatgtag gacaaggatt ctaccatgat tcgctcatgt caactagcct agaagccagt
     1561 caagtccact ttactcgtga aatgccagaa gagtttacgc tagaatgtac ggctaaattc
     1621 cgttaccgtc agcctgactc taaggtgacc gtccatgtca aaggagacaa ggcagaggtc
     1681 atctttgcgg aaccacaacg cgcgattaca ccaggccagg cagttgtctt ttacgatggc
     1741 gaagagtgtc taggtggtgg tttgattgac aatgcttacc gcgatggaca agtttgtcag
     1801 tacatttaga ttgacaaatt ttctcaattt gctacaataa taacagcaat agaaatgatg
     1861 gtcaaagctc atggatgttg caggcttttt tgtcctgcac ttctttggag ttttgactgt
     1921 ttttgtgtcg tttaagggaa aggacaagaa tgactcaaca agactttcgg acaaaagtag
     1981 acaatacggt ttttggtgtt cgggcgacag ctttgattct tcaaaatcac aagcttctag
     2041 tcaccaaaga caagggcaag tattacacta tcggcggtgc gattcaagtc aatgaaagca
     2101 cggaagacgc ggtagtccgt gaagtgaagg aagaactggg tgtcaaagct caagctgggc
     2161 agctagcttt tgtggttgaa aatcgttttg aacaggacgg tgtttcctat cacaatatcg
     2221 agtttcatta tctggtggac ttacttgagg atgccccatt gaccatgcag gaagatgaga
     2281 aaaggcagcc ctgtgagtgg attgacttgg ataagcttga ggatatccag ctagttccag
     2341 cctttttaaa aacggcccta ccagattggg aaggccaact aagacacatt catcttgagg
     2401 aataggagag aaacatgact tatcatttta ctgaagaata cgatattatt gtaattggtg
     2461 cgggacacgc tggggttgag gcttccttgg ccgctagccg tatgggctgt aaggtcctgc
     2521 ttgcgaccat caatattgaa atgctggctt tcatgccttg taatccctct atcggtggtt
     2581 ctgctaaggg gattgtcgta cgtgaagtcg atgccctcgg tggcgagatg gccaagacca
     2641 ttgacaagac ttacatccag atgaagatgc tcaacacagg gaagggccca gccgttcgtg
     2701 cccttcgtgc gcaggctgat aaggaacttt actctaagga aatgcgcaag acagttgaaa
     2761 atcaagaaaa tctgaccctt cgtcaaacca tgattgatga gattttggtg gaagatggca
     2821 aggttgtcgg tgtgcgtaca gccacccatc aagaatatgc tgctaaggct gttattgtga
     2881 cgacagggac tgctctccgt ggggaaatta tcatcggaga cctcaagtac tcatcaggtc
     2941 ctaaccacag cttggcttct attaacctag ctgacaatct caaggaactg ggtctcgaaa
     3001 tcggtcgttt caagacagga acccctccac gtgtcaaggc ttcttctatc aattacgatg
     3061 tgacggaaat tcagccagga gacgaagtgc ctaatcattt ctcatacact tcacgtgatg
     3121 aggattatgt caaagatcaa gtgccatgct ggttgaccta taccaatggt accagtcatg
     3181 agattatcca aaacaacctc caccgtgcgc ctatgtttac aggtgtggtc aagggagtgg
     3241 ggcctcgtta ctgtccgtcg attgaagaca agattgtgcg ctttgcggac aaggaacgtc
     3301 accaactctt ccttgagcca gaagggcgca atactgagga agtctatgtt caaggacttt
     3361 caaccagtct gcctgaggat gtccagcgtg acttggttca ttccatcaaa ggtttggaaa
     3421 atgcagagat gatgcggaca ggttatgcta ttgagtatga tatggtcttg cctcatcagt
     3481 tgcgtgcgac tttggaaacc aagaaaatct caggtctctt cactgctggt cagacaaatg
     3541 gaacatcagg ttatgaagaa gctgctggcc aagggattat cgcgggtatc aatgcggctc
     3601 tgaaaatcca aggtaaacct gagttgattc taaaacgaag tgacggttat atcggggtga
     3661 tgatcgacga cttggtgacc aagggaacca ttgaacctta ccgtctcttg accagtcgtg
     3721 ctgaataccg tctcattctt cgtcatgaca atgctgatat gcgcttgact gagatgggac
     3781 gcgagattgg ccttgtggat gatgaacgct gggctcgttt tgaaatcaag aaaaatcaat
     3841 ttgataatga gatgaaacgc ctagacagta tcaaactcaa gccagtcaag gaaaccaatg
     3901 ctaaggttga ggaaatgggc ttcaagccgt tgacagatgc ggtgacagcc aaagaattcc
     3961 ttcgccgtcc agaagtttct taccaagatg tggtggcctt catcggacca gctgcagaag
     4021 acttggatga caagattatc gaattgattg aaacagaaat caagtacgaa ggctatattt
     4081 caaaagccat ggatcaggtt gccaagatga aacgtatgga agaaaaacgc attccagcca
     4141 atattgactg ggatgacatc gattctattg cgacggaagc tcgtcagaag ttcaaactca
     4201 tcaatccaga aaccatcggc caagccagcc gtatttcggg agtaaaccca gcagatattt
     4261 ctattttgat ggtgtatctg gaaggtaaaa atcgtagtat ttctaaaact cttcaaaaat
     4321 caaaatgata cgtcgtcggc ttcttacgaa tgagttcaaa gcttggcttt gattcatctc
     4381 cagcctccca tagttccccg aactatggga gctaactcaa gttatgcatt ttcctagcct
     4441 tctggtctga ttttcattga gttttaatct caaaagaaag catagagaaa aacagctccg
     4501 aagacggagc tgttttgttg acttgtactc aatga
//
LOCUS       DAVBOD010000096         4347 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 640-05
            SAMEA1012484-rid20186543.denovo.097, whole genome shotgun sequence.
ACCESSION   DAVBOD010000096 DAVBOD010000000
VERSION     DAVBOD010000096.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012484
            Sequence Read Archive: ERR059358
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4347)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4347)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979948.1
            Genome Coverage       :: 595x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:03:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,266
            CDSs (total)                      :: 2,219
            Genes (coding)                    :: 2,091
            CDSs (with protein)               :: 2,091
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 71 of 128
            Pseudo Genes (incomplete)         :: 50 of 128
            Pseudo Genes (internal stop)      :: 33 of 128
            Pseudo Genes (multiple problems)  :: 22 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4347
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012484-rid20186543.denovo.097"
                     /strain="NIG 640-05"
                     /db_xref="taxon:1313"
     gene            complement(60..659)
                     /locus_tag="VQ862_002072"
     CDS             complement(60..659)
                     /locus_tag="VQ862_002072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET3116350.1"
                     /translation="MKVLVAEDQSMLRDAMCQLLTLQPDVESVLQAKNGQEAIQLLEK
                     ESVDIAILDVEMPVKTGLEVLEWIRSERLETKVVVVTTFKRPGYFERAVKAGVDAYVL
                     KERSIADLMQTLHTVLEGRKEYSPELMEVVMTHPNPLTEQEIAVLKGIARGLSNQEIA
                     DQLYLSNGTIRNYVTNILSKLDAGNRTEAANIAKESGWL"
     gene            complement(661..1758)
                     /locus_tag="VQ862_002073"
     CDS             complement(661..1758)
                     /locus_tag="VQ862_002073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HET3116351.1"
                     /translation="MLERLKSIHYMFWISLIFMVFPILPVVTGWLSAWHLLIDILFVV
                     AYLGVLTTKSQRLSWLYWGILLTYVVGNTAFVAVNYIWFFFFLSNLLSYHFSVGGLKS
                     LHVWTFLLAQVLVVGQLLIFQRIEVEFLVYLLVILAFVDLMTFGLVRIRIVEDLKEAQ
                     VKQNAQINLLLAENERNRIGQDLHDSLGHTFAMLSVKTDLALQLFQMEAYPQVEKELK
                     EIHQISKDSMNEVRTIVENLKSRTLTSELETVKKMLEIAGIEVQVENHLDKASLTQDV
                     ESMASMILLELVTNIIKHAKASKAYLKLERTEKELILTVSDDGCGFAFLKGDELHTVR
                     DRVFPFSGEVSVISQKHPTEVQVRLPYKERN"
     gene            complement(1758..2495)
                     /locus_tag="VQ862_002074"
     CDS             complement(1758..2495)
                     /locus_tag="VQ862_002074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004249339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET3116352.1"
                     /translation="MKRWIALSKIEFLLTKRQLIYYLLSVGMPTAFYLFFSGIYQDTP
                     GELANFMRDYLISMTAFSMMSTTILSFPAVLHTDKMNNWQKTLRHSPVNMVEYYLSKI
                     TSMLVDYLVSILVVFTVGHFVRGVDMPLVKWVGAAILLIVGSIAFVALGLTLTLLPTS
                     QLMSVVGNLLYLGLAVLGGLWMPISLFPDWMQVVGKCLPTYQLMELLKTFLNEGGINL
                     SATVYLLVFSVVLFGLTIYLQGHKENA"
     gene            complement(2497..3381)
                     /locus_tag="VQ862_002075"
     CDS             complement(2497..3381)
                     /locus_tag="VQ862_002075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3116353.1"
                     /translation="MTVVKVEKLSKKIKDKEILRNISFEINDGECVALIGPNGAGKTT
                     LLDCLLGDKLVTSGQVSIQGLPVTSSKLDYTRAYLPQENVIVQKLKVKELIAFFQRIY
                     PNPLSNQEIDQLLQFVKQQKEQLAEKLSGGQKRLFSFVLTLIGRPKIVFLDEPTASMD
                     TSTRQRFWEIVQELKAQGVTILYSSHYIEEVEHTADRILLLNKGELIRDTTPLAMRSE
                     EIEKHFILPIAYKEVVEQSNLVENWTLKQDSLQVVTREADAFWELLAQAGCRMQEIEV
                     NNRSLLNTIFEETQKGDN"
     gene            complement(3368..3562)
                     /locus_tag="VQ862_002076"
     CDS             complement(3368..3562)
                     /locus_tag="VQ862_002076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000820182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3116354.1"
                     /translation="MKRGIIYFFIGLSLLVWLVEMFTDWFDQALLCQFIRGALEFGFM
                     IFVVFPMGMEWLKGESHDGG"
     gene            complement(3559..3765)
                     /locus_tag="VQ862_002077"
     CDS             complement(3559..3765)
                     /locus_tag="VQ862_002077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000503440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3116355.1"
                     /translation="MGEEEMRNKMIIAMSLVVAGVMTYLMFSGLDEDFYHFPWKVFAG
                     FGIMSWLVREGLKLVRDVKKEFEE"
BASE COUNT         1421 a          963 c          701 g         1262 t
ORIGIN      
        1 tattgttcca ttcactaccg tcaattttag cacatagtct tcatgaaaat attatatcat
       61 cataaccaac cagattcttt tgcgatatta gctgcctctg ttcgattacc agcatccagt
      121 tttgaaagaa tattggtgac atagtttcga atagttccgt ttgagaggta aagctgatct
      181 gcgatttctt ggttggataa gccccgggcg attcccttta aaacagcaat ctcttgttct
      241 gtcaacggat taggatgcgt catcaccact tccatcaatt caggcgaata ctccttgcgc
      301 ccttcgagga cggtgtgcaa ggtttgcatg aggtctgcaa tgcttctttc tttcaagaca
      361 taagcatcca ctccagcctt gaccgcacgt tcaaaatacc ctggacgctt gaaggtcgtc
      421 accacaacca cctttgtttc aagcctttct gatcgtatcc actccaagac ttcaagacct
      481 gtcttaacag gcatttctac gtcaaggatg gcgatatcta cagactcctt ttctaatagt
      541 tggattgctt cttgcccatt cttggcttga aggacagact ccacatctgg ttgaagcgtg
      601 agcaattgac acatggcatc tcgcaacata ctttgatctt ctgcgactaa tactttcatc
      661 ttagtttctc tccttataag gtagtcgaac ttgcacttcc gttggatgtt tctgactgat
      721 tacacttact tctcctgaaa atggaaaaac acgatctcgg actgtatgga gctcatctcc
      781 ttttagaaaa gcaaagccgc agccatcatc acttactgtt aaaatgagtt ccttctctgt
      841 ccgttctaat tttaagtaag ctttagacgc tttggcatgt ttgatgatat tggtcaccaa
      901 ctcaagcaaa atcatagaag ccattgactc cacatcctgg gtcaagctag ccttgtctaa
      961 gtgattctca acttgaacct caattccagc aatttctaac atctttttca cagtctctag
     1021 ttcggatgtc aaagttctag acttaagatt ttccacaatg gttcgcactt cattcatgga
     1081 atccttgctg atctggtgaa tttcttttaa ttccttttcc acctgtggat aagcctccat
     1141 ctgaaataac tgcaaggcta gatcagtttt aacactaagc atagcaaagg tatgccccag
     1201 actatcatgc aaatcttgac cgatacgatt gcgttcattt tcagcaagca atagatttat
     1261 ctgggcattt tgcttaacct gtgcttcttt caaatcctcc acaattcgaa tccgaaccaa
     1321 gccaaaagtc attaaatcga caaaagcaag aattacaagt agatagacta gaaactcaac
     1381 ttcgattctc tgaaaaatca acagttgacc cacaacaagg acttgagcaa gaagaaaagt
     1441 ccagacatgt aaagacttta aaccacctac gctgaaatga tagcttaaga gattggatag
     1501 gaaaaagaaa aaccagatat aattaacagc cacaaaggca gtattcccaa ctacataagt
     1561 cagcaggatg ccccaatata gccaagatag acgctggctc ttagttgtta aaacacccaa
     1621 atacgccact acaaatagaa tatcaatcaa taaatgccag gcagaaagcc acccagtcac
     1681 tacaggtagg atggggaaaa ccataaaaat taaactgatc caaaacatat aatgtatgct
     1741 tttcagtctt tcaagcatta agcattctcc ttatgacctt gaaggtaaat ggtcaaacca
     1801 aacaaaacta ctgaaaaaac aagtaaataa actgtggctg atagattgat gccaccctca
     1861 tttaagaagg tcttgagcaa ctccatcaac tgataggtcg ggagacactt acctactact
     1921 tgcatccagt ctggaaataa agaaatgggc atccagagtc cgcctaaaac agccaatcct
     1981 agataaagaa gattgcccac aacagacatc agctgactag ttggtaagag agtcaaggtc
     2041 aagccaagtg ctacaaaagc aatactcccc acaatcagca aaatcgcagc tccaacccat
     2101 tttactagag gcatgtctac acctcttaca aaatgtccaa ctgtaaaaac aaccagaatt
     2161 gagaccaaat aatcaaccag catacttgtt atctttgata gataatattc taccatattt
     2221 acagggctat gacgcaatgt tttctgccag ttgttcatct tatcggtatg taaaacagct
     2281 ggaaatgaga ggatagttgt cgacatcatg gaaaaggcag tcatggagat gaggtaatca
     2341 cgcataaaat tcgcgagttc acctggtgtg tcctgataga taccagaaaa aaataaatag
     2401 aaagccgtcg gcatccctac cgacaataga taatagatta attgtcgttt ggtcaataaa
     2461 aattctatct tactaagtgc tatccatcgt ttcatcttag ttatctccct tctgcgtctc
     2521 ttcaaagatt gtattcaaca aactacgatt attaacttcg atttcttgca tcctacatcc
     2581 tgcttgggct aatagttccc agaaagcatc tgcttctcga gtgactactt gtaaagaatc
     2641 ttgctttagg gtccagtttt caaccaaatt tgactgctct acgacttcct tgtaagctat
     2701 aggaaggata aagtgctttt ctatttcctc gctacgcata gctagaggcg tcgtatctcg
     2761 aatcaactct cccttattta agagcaaaat gcggtctgca gtgtgttcca cttcctcaat
     2821 ataatgggac gaatagagaa tggtgactcc ttgcgctttt aactcctgga caatttccca
     2881 aaaacgttga cgagttgagg tatccatgga cgcagtaggc tcatctaaaa aaacaatctt
     2941 tggtcgccca attaaggtca agacgaaaga aaagagacgc ttttgaccgc ctgataattt
     3001 ttctgccaac tgttcttttt gttgcttgac aaactgcaat agttgatcaa tttcctgatt
     3061 gctcaaagga tttggataga tacgttgaaa gaaagcaatc aactctttaa cttttaattt
     3121 ctgaacgatt acattttctt gagggaggta agccctagta tagtctaact tagaactcgt
     3181 cactggtaaa ccttgaatag atacttgacc gcttgtgacc agtttatctc caagcaaaca
     3241 atctaagagt gttgtctttc cggcaccatt tggaccaatt aaggcaacac attcaccatc
     3301 gttgatttca aaggagatgt tccgcaaaat ttccttgtct tttattttct tactcaattt
     3361 ctcaacttta accaccgtca tgagactctc ctttcaacca ctccattccc atagggaaaa
     3421 cgacgaaaat cataaatcca aactccaaag caccacgaat gaattggcaa agcaaggctt
     3481 gatcaaacca atcagtaaac atttccacta accataccaa gagtgacagg ccgataaaga
     3541 aatagatgat ccctctcttc attcttcaaa ctcctttttc acatctctga ctaatttcaa
     3601 accttctcta acaagccaag acatgattcc aaagccagca aagaccttcc aaggaaaatg
     3661 gtagaaatcc tcatccaatc ccgaaaacat gagataggtc ataactcctg ctactactaa
     3721 actcattgca ataatcattt tatttctcat ctcttcttcc cccatttcat actacaatta
     3781 tagtctttta aaatcagagg aggcagaagc ttctgtcact agaaaatatg acaaatgtca
     3841 taaaaaattc tgttcaaaac aagcaagata cattatacaa taaaacacaa tcagaaaaat
     3901 ctaaggcaac ttcctcaaaa gagatatcaa actcaattca caccataatg taaactaata
     3961 cttatttaaa atcaaaaaga gtagaaattt ttatcagaca aacacatata tagtgtattg
     4021 aatctataac agtaggcctt aaatactaaa atatttctat aaattaattt aactttcctg
     4081 atagagctgt tcatatctta tttcaattct ctatattata cgttgaacaa aacccttcta
     4141 ttgctttctt aaaaatttat aagagttata aaatctgtta aatttcaatg tgtataccta
     4201 aactacggta tttattgaaa agactggaga caaaaagtat acgctgccaa aatgaattac
     4261 tgaaaatcaa aaaagagaga accaaactga ttccctctta atgtatataa tatctagttt
     4321 taaaaataca cactcacata tctctgt
//
LOCUS       DAVBOD010000097         4312 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 640-05
            SAMEA1012484-rid20186543.denovo.098, whole genome shotgun sequence.
ACCESSION   DAVBOD010000097 DAVBOD010000000
VERSION     DAVBOD010000097.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012484
            Sequence Read Archive: ERR059358
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4312)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4312)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979948.1
            Genome Coverage       :: 595x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:03:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,266
            CDSs (total)                      :: 2,219
            Genes (coding)                    :: 2,091
            CDSs (with protein)               :: 2,091
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 71 of 128
            Pseudo Genes (incomplete)         :: 50 of 128
            Pseudo Genes (internal stop)      :: 33 of 128
            Pseudo Genes (multiple problems)  :: 22 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4312
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012484-rid20186543.denovo.098"
                     /strain="NIG 640-05"
                     /db_xref="taxon:1313"
     gene            complement(1..210)
                     /locus_tag="VQ862_002078"
                     /pseudo
     CDS             complement(1..210)
                     /locus_tag="VQ862_002078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007897432.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(286..720)
                     /locus_tag="VQ862_002079"
     CDS             complement(286..720)
                     /locus_tag="VQ862_002079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000927991.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET3116356.1"
                     /translation="MLLVLVSLVHSFGSVSIIAHTIHQKFNLKVPNYRQEEDWARMGL
                     PITRKEISNWHIKASQYYLESLYNLLREKLLEQPLLHADETSYRVLESDSHLTYYWTF
                     LSGKAENQAITLYHHDQRRSGLVVQEFLGDYSGYVHCDMLRQ"
     gene            complement(796..1646)
                     /gene="rfbD"
                     /locus_tag="VQ862_002080"
                     /pseudo
     CDS             complement(796..1646)
                     /gene="rfbD"
                     /locus_tag="VQ862_002080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017647909.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose reductase"
     gene            complement(1712..2761)
                     /gene="rfbB"
                     /locus_tag="VQ862_002081"
     CDS             complement(1712..2761)
                     /gene="rfbB"
                     /locus_tag="VQ862_002081"
                     /EC_number="4.2.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000141505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-glucose 4,6-dehydratase"
                     /protein_id="HET3116357.1"
                     /translation="MTEYKNIIVTGGAGFIGSNFVHYVYENFPDVHVTVLDKLTYAGN
                     RANIEEILGNRVELVVGDIADAELVDKLVAQADAIVHYAAESHNDNSLNDPSPFIHTN
                     FIGIYTLLEAARKYDIRFHHVSTDEVYGDLPLREDLPGHGEGPGEKFTAETKYNPSSP
                     YSSTKAASDLIVKAWVRSFGVKATISNCSNNYGPYQHIEKFIPRQITNILSGIKPKLY
                     GEGKNVRDWIHTNDHSSGVWTILTKGQIGETYLIGADGEKNNKEVLELILKEMGQATD
                     AYDHVTDRAGHDLRYAIDASKLRDELGWKPEFTNFEAGLKATIKWYTDNQEWWKAEKE
                     AVEANYAKTQEIITV"
     gene            complement(2771..3367)
                     /locus_tag="VQ862_002082"
     CDS             complement(2771..3367)
                     /locus_tag="VQ862_002082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000131470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose 3,5-epimerase family
                     protein"
                     /protein_id="HET3116358.1"
                     /translation="MTDNFFGKTLAARKVEAIPGMLEFDIPVHGDNRGWFKENFQKEK
                     VLPLGFPESFFAEGKLQNNVSFSRKNVLRGLHAEPWDKYISVADGGKVLGSWVDLREG
                     ETFGNTYQTVIDASKGIFVPRGVANGFQVLSDTVSYSYLVNDYWALELKPKYAFVNYA
                     DPSLGIEWENLEEADVSEADKHHPLLKDVKPLKKEDLE"
     gene            complement(3368..4225)
                     /gene="rfbA"
                     /locus_tag="VQ862_002083"
     CDS             complement(3368..4225)
                     /gene="rfbA"
                     /locus_tag="VQ862_002083"
                     /EC_number="2.7.7.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000676139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate thymidylyltransferase RfbA"
                     /protein_id="HET3116359.1"
                     /translation="MKGIILAGGSGTRLYPLTRAASKQLMPVYDKPMIYYPLSTLMLA
                     GIRDILIISTPQDLHRFQELLQDGSEFGIKLSYAEQPSTDGLAIGEEFISDDSVALIL
                     GDNIYHGPGLSTMLQKAAKKEKGATVFGYQVKDPERFGVVEFDTDMNAISIEEKPEYP
                     RSNYAVTGLYFYDNDVVEIAKSIKPSPRGELEITDVNKVYLDRGDLSVELMGRGFAWL
                     NTGTHESLLEASQYIETVQRMQNVQVANLEEIAYRMGYISREDVLALAQPLKKNEYGQ
                     YLLRLIGEA"
BASE COUNT         1203 a         1008 c          782 g         1319 t
ORIGIN      
        1 tttctgtagt cgttcatcag ctggcaaagc ctcccagtct ctttccaagg aaaataactg
       61 atcacaataa gctaaacctt tagctcctaa ggatgattta tccgtttgct tggggggcgc
      121 ttcaaaaaac ttccttctca catgtgccca acatccaaca agttcagctt cttccagttg
      181 acgataagct tctagcggtt cgcagtttac caagcttagc gtcgccttgc tcctaaacct
      241 tggactgcta tcgcataggc agaactagag gactaaagtc ctaagttact gccgcaacat
      301 atcacaatgc acatagccag aataatctcc taggaattct tgtactacta aaccactccg
      361 acgctgatca tggtggtaca gcgtgattgc ttgattctca gctttcccag acaaaaaagt
      421 ccaatagtag gtcagatggc tatcactctc tagaacccga taagaggttt catccgcatg
      481 aagaagaggt tgttctaaca acttttctcg taaaaggtta taaagggact ctaaatagta
      541 ttgacttgcc ttgatatgcc aattagagat ttccttacgt gtgattggta aacccatcct
      601 agcccaatct tcttcttggc gataattggg taccttcaga ttaaacttct gatggatggt
      661 gtgagcgata atagaaactg agccaaagct atgcaccaaa gagaccagca ccaacaacaa
      721 gataattgta catcttaagc tcctttggag ttcattatct gcctctttta ttagactaga
      781 aaatcattct actacttatc tcacttcttg tttgtaaaat tcttgcaatg catcttgcca
      841 agttggaata acaaatccag tagctttggc tttggccagg ctcatcgttg agtttagcgg
      901 acgttgagct ttggctggaa attgactgga tctactggct tgacttcgac atctgtatct
      961 ttcaaaattt caactgcaaa atcataccat gttgtgtctt ctgtcgcatc atttgacaaa
     1021 tgataataac caaattcctt acgattttca gctaggtaga tcatgaattc agccaaggta
     1081 cgagtccaag tcggacgacc gtactggtca tttacaactg ttaaagtctt atgagttttc
     1141 gcaagatttt gcatggtaaa aacgaagttt ttgccataat ttccaaatac ccaggcagta
     1201 cggataatat agaaattaga cacatgcttc tcaactaact cttcccccat acgcttagtg
     1261 cgtccatatt ctgtctgtgg atctggtcgg tcatcaactt cccactcttg tccaactggt
     1321 ttcttaccgt caaagaccta gtccgtagaa atataaacta gagttgcacc atgcttttca
     1381 gatgcttttg cgacattttt tgtccccatc acattgatgg cgaagtccaa ctcttttcct
     1441 tcatcctctg ctgcatcaac agcggtgtag gctgcacaat ggtagactaa agtcggtttc
     1501 acctcttcaa aaactttctc aaccatttct tcattggtaa tgtccatctc agccacatct
     1561 actgccacgt attcttcatt acgttcatcc aataaatagc gaagttccgt tcctaattgg
     1621 ccatttgccc ctgtaattaa aatcatctct agacctttct aatatgtaac tcttcccaat
     1681 atagcaataa aaagcagcga tttcctgctt tttatactgt aataatctcc tgagtcttag
     1741 cataattggc ttcaacagct tctttttctg ctttccacca ttcttggtta tctgtatacc
     1801 acttgattgt tgccttgagc ccagcttcaa agttggtaaa ttcaggtttc caccccaact
     1861 catcacggag cttgctggca tcaatcgcat agcgaaggtc atgtcctgca cggtcagtca
     1921 catgatcata ggcatccgta gcttgtccca tttccttaag gataagttcc aaaacttcct
     1981 tattgttctt ctcaccatca gccccaatca agtaggtttc accgatttgc ccttttgtca
     2041 agattgtcca aactcctgaa gaatggtcat tggtatgaat ccagtcacga acgttcttac
     2101 cttcaccgta aagttttggc ttaattccac ttaggatgtt agtaatctga cgtgggatga
     2161 atttttcgat atgttgataa ggaccgtagt tatttgaaca gttggaaatc gttgccttga
     2221 ctccaaaaga acgcacccag gctttgacaa tcaagtctga tgcggccttg gttgatgagt
     2281 acggagagct tgggttgtat tttgtttcag cagtaaattt ctcacctggt ccttcaccat
     2341 gacctggcaa atcttctcgt aaagggagat ccccataaac ttcatctgtc gatacatggt
     2401 ggaagcgaat atcatactta cgagcagctt ctaaaagagt atagattcca atgaagttag
     2461 tatgaataaa tggcgatgga tcattgagcg aattatcatt gtggctttcc gctgcataat
     2521 gaacgatagc atctgcttga gcaaccaact tgtctaccaa ctccgcatca gcaatgtcac
     2581 caacaactaa ctcaacacga ttgcctaaaa tttcctcaat attcgcgcgg tttccagcat
     2641 aagtcaactt atctaggact gtcacgtgaa catctggaaa gttctcgtaa acataatgga
     2701 caaagttaga accgataaag ccagctccac ctgtcacgat aatatttttg tattcagtca
     2761 tattctttcc ttattccaaa tcttcttttt tcaaaggctt cacgtcctta agtaggggat
     2821 gatgtttgtc tgcttcagat acgtctgctt cttccagatt ttcccattca ataccaaggc
     2881 ttggatcagc gtagttcaca aaggcatact tgggtttgag ttcaagagcc cagtaatcat
     2941 tgaccagata gctatatgac actgtatctg ataaaacttg gaagccatta gctacgcctc
     3001 gaggaacaaa gattcccttg cttgcatcaa ttactgtctg ataggtattc ccaaaggttt
     3061 caccctcgcg tagatcaacc caagaaccca gaactttccc tccatctgct acagagatgt
     3121 acttatccca aggctctgcg tggaggcctc gaaggacatt tttacgtgag aaggatacat
     3181 tgttttgcaa ttttccttct gcaaagaaag actctggaaa tccaagtgga agcacttttt
     3241 ccttttggaa attttcttta aaccagccac gattatctcc atgaacgggg atatcaaact
     3301 ccaacatgcc tggaatagct tcaaccttgc gtgccgcaag cgtcttaccg aaaaaattat
     3361 ctgtcatcta tgcttctcca atcaaacgga gcagatactg tccgtattca tttttcttaa
     3421 gtggttgggc taaggccaat acatcttctc gactgatata gcccatacgg taagcaattt
     3481 cttctaagtt tgctacctga acattttgca tccgttgcac tgtttcgatg tactgtgaag
     3541 cctctagtaa actttcatga gttccagtat tcagccaagc aaagccacgt cccataagct
     3601 caacagacaa atcaccacga tctaggtaaa ccttgtttac atctgtaatt tccagttcac
     3661 cacgagggct tggtttaata ctcttggcaa tttcgacaac atcgttatca tagaaataca
     3721 gtcctgtcac tgcatagttg gagcgaggat actccggttt ttcttctatg gaaatagcat
     3781 tcatgtctgt atcaaactca accacaccaa aacgctctgg atccttcact tggtagccaa
     3841 aaacagtcgc acctttctct ttcttggctg ctttttgaag cattgtgctc agaccaggac
     3901 catggtagat attgtcgcct aaaatcaagg caacgctatc gtcagaaata aactcttccc
     3961 caattgccaa accatctgta cttggttgct ctgcataaga aagtttgatc ccaaactcag
     4021 atccgtcttg aagaagctct tgaaatcgat gtaaatcctg tggagtggaa ataatcaaaa
     4081 tatccctaat cccagccaac atcaatgttg aaagtgggta gtaaatcatc ggtttatcat
     4141 aaaccggcat aagttgtttt gacgcagcgc gagtcaaagg atataaacgt gtccccgaac
     4201 cacctgctag aataatacct ttcatagtag ggtacctttc tttgttattt tagagtcaat
     4261 tactattaat tgtgtactgc tctaaaaaga aaacaatcat cccatgtttt at
//
LOCUS       DAVBOD010000098         4287 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 640-05
            SAMEA1012484-rid20186543.denovo.099, whole genome shotgun sequence.
ACCESSION   DAVBOD010000098 DAVBOD010000000
VERSION     DAVBOD010000098.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012484
            Sequence Read Archive: ERR059358
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4287)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4287)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979948.1
            Genome Coverage       :: 595x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:03:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,266
            CDSs (total)                      :: 2,219
            Genes (coding)                    :: 2,091
            CDSs (with protein)               :: 2,091
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 71 of 128
            Pseudo Genes (incomplete)         :: 50 of 128
            Pseudo Genes (internal stop)      :: 33 of 128
            Pseudo Genes (multiple problems)  :: 22 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4287
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012484-rid20186543.denovo.099"
                     /strain="NIG 640-05"
                     /db_xref="taxon:1313"
     gene            1..142
                     /locus_tag="VQ862_002084"
                     /pseudo
     CDS             1..142
                     /locus_tag="VQ862_002084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(135..308)
                     /locus_tag="VQ862_002085"
     CDS             complement(135..308)
                     /locus_tag="VQ862_002085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001022221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteinase"
                     /protein_id="HET3116360.1"
                     /translation="MNIKKRVLSAGLTFASVLLLAAYGQSGSDTKTYSSTFSGNPTTF
                     NYLLDYYTDNIVN"
     gene            complement(467..2074)
                     /locus_tag="VQ862_002086"
     CDS             complement(467..2074)
                     /locus_tag="VQ862_002086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HET3116361.1"
                     /translation="MQEKWWHNAVVYQVYPKSFMDSNGDGIGDLPGITSKLDYLAKLG
                     ITAIWLSPVYDSPMDDNGYDIADYQAIATIFGTMEDMDQLIAEAKKRDIRIIMDLVVN
                     HTSDEHAWFVEACENPNSPERDYYIWRDEPNDLDSIFSGSAWEYDEKSGQYYLHFFSK
                     KQPDLNWENEKLRQKIYEMMNFWIDKGIGGFRMDVIDMIGKIPDEKVVNNGPMLHPYL
                     KEMNQATFGDKDLLTVGETWGATPEIAKLYSDPKGQELSMVFQFEHIGLQYQEGQPKW
                     HYQKELNIAKLKEIFNKWQTELGVEDGWNSLFWNNHDLPRIVSIWGNDQEYREKSAKA
                     FAILLHLMRGTPYIYQGEEIGMTNYPFETLDQVEDIESLNYAREALEKGVPIEEIMDS
                     IRVIGRDNARTPMQWDESKNAGFSTGQPWLAVNPNYEMINVQEALANPDSIFYTYQKL
                     VQIRKENSWLVRADFELLDTADKVFAYIRKDGDRRFLVVANLSNEEQDLTVEGKVKSV
                     LIENTLAQEVFEKQILVPWDAFCVELL"
     gene            2227..3711
                     /locus_tag="VQ862_002087"
     CDS             2227..3711
                     /locus_tag="VQ862_002087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008535024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1846 domain-containing protein"
                     /protein_id="HET3116362.1"
                     /translation="MKKQAFSSEQYLNLQRDHILERINQFDGKLYLEFGGKMLEDFHA
                     ARVLPGYEPDNKIKLLQELKEQVEVVIAINASNIEHSKARGDLGISYDQEVLRLIDKF
                     NELGIFVGSVVITQYAGQPAADAFRNQLEKNGIDSYLHYPIKGYPTDMDHIISPEGMG
                     KNDYIKTSRNLIVVTAPGPGSGKLATCMSNMYHDQINGIKSGYAKFETFPVWNLPLHH
                     PVNLAYEAATADLDDVNMIDPFHLQTYGETTVNYNRDIEIFPVLKRMLERILGKSPYA
                     SPTDMGVNMVGFAITDDEAAVEASKQEIIRRYYQTVLDFKAEKVGEAAVKKIELLMND
                     LGITPADRKVAVVARQKAEETGGPALAFELPNGEIITGKNSELFGPTAAALINAIKKS
                     ADIAKEVKLIEPEVVKPIQGLKIDHLGSRNPRLHSNEILIALAITATENPDAARAMEE
                     LGNLKGSEAHSTIILTDEDKNVLRKLGINVTFDPYYQYDRLYRK"
     gene            3806..>4287
                     /locus_tag="VQ862_002088"
     CDS             3806..>4287
                     /locus_tag="VQ862_002088"
                     /EC_number="4.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002893508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteine lyase"
                     /protein_id="HET3116363.1"
                     /translation="MSKEVIVESFELDHTIVKAPYVRLIGEETGPKGDIISNYDIRLV
                     QPNEDSIPTAGLHTIEHLLAKLIRTRIDGMIDCSPFGCRTGFHMIMWGRHTSAKIAAV
                     IKDSLKEIAETTTWEDVPGTTIESCGNYKDHSLFSAKEWAKLILEQGISDDAFERHVI
                     "
BASE COUNT         1240 a          979 c          816 g         1252 t
ORIGIN      
        1 cttttacctc ttcctcccta ctcacctgag tacaatccta ttgagaaaac atgggctcat
       61 atcaaaaagc acctcataaa aggtattacc aagttgcaat accttttatg aggctctttt
      121 gtcttgttct tgtttcaatt gactatatta tcagtgtaat agtctaatag atagttaaat
      181 gtagttggat ttccactaaa ggttgatgag taagtttttg tatctgaacc tgattggccg
      241 taagcagcta aaagcaaaac agatgcaaaa gtcaggcctg cactaaggac acgcttcttt
      301 atgttcatct tctttctcct taatagtggg aatttgtaaa gttaattgaa tttcgagaat
      361 gaaagtttat aaaccttggt tataaaaaac aaaggatttc tgctttttat acagtcctcc
      421 cttgttttta tatgatttca attttaaatt tttctgcaaa aaatatttat agtaattcca
      481 cacagaaagc atcccatgga actaagattt gtttttcaaa gacttcttga gctagggtgt
      541 tttcaatcaa gacagatttg acttttcctt ctactgtcaa gtcttgctct tcattggaca
      601 agttagccac aactaggaag cgacggtcgc catccttacg tatataagca aagaccttat
      661 cagccgtatc aagcaattca aagtcagctc gaactagcca gctattctcc ttgcgaattt
      721 ggaccagttt ctgataggta tagaaaatag aatctggatt tgccagcgct tcttggacat
      781 tgatcatctc gtaatttgga ttaaccgcca accaaggttg acctgttgag aaaccagcgt
      841 ttttgctctc gtcccattgc ataggggtac gggcattgtc acgtccaata acacggatac
      901 tgtccatgat ttcttcaatc ggaacacctt tttcaagagc ctcacgcgca tagttgagag
      961 attcaatatc ttctacttga tccagcgttt caaagggata gttggtcatg ccaatttcct
     1021 caccttggta gatataagga gttcctctca tgagatgaag caagatggca aaggctttgg
     1081 cagatttttc gcggtattct tggtcatttc cccagattga gacaatacga gggaggtcat
     1141 ggttgttcca gaagagggaa ttccagccgt cctcaactcc taactctgtc tgccatttgt
     1201 tgaagatttc ttttaactta gcgatattca gctctttttg atagtgccat ttaggctgac
     1261 cttcctgata ctgaagaccg atatgttcaa actggaagac catagacaat tcttgcccct
     1321 ttggatcaga gtagagcttg gcaatctctg gcgttgctcc ccaagtctcc cctactgtca
     1381 agagatcctt atctccaaag gtcgcctgat tcatttcctt gagataggga tggagcatag
     1441 gaccattatt gactaccttc tcgtcaggaa ttttgccaat catgtcaata acatccatac
     1501 ggaaaccacc aataccctta tcaatccaga agttcatcat ctcataaatt ttctggcgaa
     1561 gtttttcatt ttcccagttg agatccggct gtttcttgct gaaaaagtgg agatagtatt
     1621 gacctgactt ttcatcgtat tcccaagcag acccactaaa gatagaatct aggtcattgg
     1681 gttcatcgcg ccagatatag tagtctcgct cagggctatt aggattttca caggcctcta
     1741 caaaccaggc atgctcatcc gaggtatgat tgaccaccaa gtccatgatg atacggatat
     1801 cacgcttctt agcttctgca atcagttgat ccatatcctc catggttcca aaaatcgttg
     1861 caatcgcttg ataatcagca atatcgtagc cattatcatc catagggctg tcataaacgg
     1921 gagaaagcca aattgctgtg attcctagct tggctagata gtccaactta ctggtaattc
     1981 ctggcaaatc gccaattcca tctccattac tatccataaa actctttgga tagacttgat
     2041 agactacggc attgtgccac catttttctt gcatcttctt acctcattat tttcataatc
     2101 tatagtctat gatagcactt tttaaaattt tgtgcaagcg tttgcttaat ctttttaatt
     2161 tcttttttag ctccgtagtt tcctaacttc caatttttta ttataataga gtccagaggt
     2221 aaaaaaatga aaaaacaagc ttttagttct gaacaatatt tgaatttaca acgcgaccat
     2281 attttggagc gcattaacca atttgacggc aagctctact tagagtttgg cggtaaaatg
     2341 ttagaagatt tccacgctgc tcgtgtcctt cctggttatg aacctgacaa caaaatcaag
     2401 ctcttgcaag aattgaaaga gcaggttgag gttgtgattg ccattaatgc tagcaacatt
     2461 gaacattcca aagcacgtgg cgacttaggc atttcttatg accaagaagt tcttcgtttg
     2521 attgacaaat tcaatgaatt agggattttt gttggttccg ttgtcattac acaatacgct
     2581 ggccaacccg ctgcagatgc cttccgcaat caacttgaga aaaacggaat tgattcttat
     2641 cttcattatc caatcaaagg atatccgacg gatatggatc acatcatttc cccagaaggc
     2701 atgggcaaaa acgactacat caaaaccagt cgcaacttga ttgtcgtaac cgctcctgga
     2761 cccggttctg gaaaattggc aacgtgtatg tccaatatgt accacgacca aatcaatggc
     2821 atcaagtctg gctacgctaa atttgaaacc ttccctgttt ggaatcttcc ccttcatcac
     2881 ccagttaact tggcttatga agctgccaca gctgaccttg atgatgtcaa catgattgac
     2941 cccttccatc ttcaaaccta tggagaaacc actgtcaact acaaccgtga tatcgaaatc
     3001 ttcccagtgc tcaagcgcat gttggaacgt attctcggaa aatcaccata cgcttcaccg
     3061 acagatatgg gtgtcaacat ggttggtttc gctattacag atgacgaggc tgctgtcgaa
     3121 gcttctaaac aagaaatcat ccgccgttac tatcaaacag ttcttgactt caaagctgaa
     3181 aaagttggcg aagctgccgt caagaaaatt gagttactca tgaacgacct cggtatcaca
     3241 cctgcagacc gtaaggttgc tgtcgttgcg cgccaaaaag cagaagaaac tggtggacca
     3301 gccctagcct ttgaattgcc aaatggggaa atcatcactg gtaagaactc agaactcttt
     3361 ggccctacag ccgctgcctt gatcaatgcc atcaaaaaat cagctgacat cgctaaagaa
     3421 gtaaaactaa tcgagcctga agttgttaag ccaatccaag gtcttaaaat cgatcatctc
     3481 ggtagccgca atccacgcct tcattcaaat gaaatcctga ttgcacttgc tatcacagct
     3541 acagaaaatc ctgatgctgc ccgcgctatg gaagaactcg gcaacctcaa aggaagcgaa
     3601 gcccactcaa ccatcatctt gactgatgaa gacaagaatg tccttcgtaa actgggtatc
     3661 aacgtaacct ttgacccata ctaccaatac gaccgcttat atcgtaagta aagatttcaa
     3721 cctctccagc ctcggagagg ttttctctct gtctcaggag caacctttat gatataatga
     3781 gagaagaaaa ctgaaaggat ttaccatgtc aaaagaagtt attgtcgaaa gttttgaact
     3841 tgaccacacc attgtcaaag caccctatgt tcgcttgatt ggggaagaaa caggaccaaa
     3901 aggagacatc atctccaatt atgatattcg cttggtgcaa ccaaacgaag actctatccc
     3961 tactgccggc cttcacacta tcgagcacct cttagccaaa ctcatccgta cccgcattga
     4021 cggcatgatt gactgttcac catttggttg ccgcacaggc ttccacatga ttatgtgggg
     4081 acgtcacacc agtgctaaaa tcgcagctgt tatcaaggat tcgctcaagg aaatcgctga
     4141 aactactact tgggaagatg tcccagggac aaccatcgaa tcttgcggaa actacaagga
     4201 ccacagcctc ttctctgcta aagaatgggc aaaactcatc ttggaacaag ggatttcaga
     4261 tgatgccttt gaacgtcatg tgattta
//
LOCUS       DAVBOD010000099         4193 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 640-05
            SAMEA1012484-rid20186543.denovo.100, whole genome shotgun sequence.
ACCESSION   DAVBOD010000099 DAVBOD010000000
VERSION     DAVBOD010000099.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012484
            Sequence Read Archive: ERR059358
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4193)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4193)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979948.1
            Genome Coverage       :: 595x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:03:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,266
            CDSs (total)                      :: 2,219
            Genes (coding)                    :: 2,091
            CDSs (with protein)               :: 2,091
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 71 of 128
            Pseudo Genes (incomplete)         :: 50 of 128
            Pseudo Genes (internal stop)      :: 33 of 128
            Pseudo Genes (multiple problems)  :: 22 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4193
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012484-rid20186543.denovo.100"
                     /strain="NIG 640-05"
                     /db_xref="taxon:1313"
     gene            720..1712
                     /locus_tag="VQ862_002089"
     CDS             720..1712
                     /locus_tag="VQ862_002089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HET3116364.1"
                     /translation="MAMIEVEHLQKNFVKTVKEPGLKGALRSFIHPEKQTFEAVKDLT
                     FEVPKGQILGFIGANGAGKSTTIKMLTGILKPTSGFCRINGKIPQNNRQDYVKDIGVV
                     FGQRTQLWWDLALQETYTVLKEIYDVPNSLFHKRMDFLNEVLDLKDFIKDPVRTLSLG
                     QRMRADIAASLLHNPKVLFLDEPTIGLDVSVKDNIRRAITQINKEEETTILLTTHDLS
                     DIEQLCDRIFMIDKGQEIFDGTVSQLKETFGKMKTLSFELLPGQSHLVSHYEGLSDMT
                     IDRQGNSLNIEFDSSRYQSADIIKQTLSDFEIRDLKMVDTDIEDIIRRFYRKEL"
     gene            1714..2532
                     /locus_tag="VQ862_002090"
     CDS             1714..2532
                     /locus_tag="VQ862_002090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000240175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-2 family transporter protein"
                     /protein_id="HET3116365.1"
                     /translation="MIKLWRRYKPFINAGVQELITYRVNFILYRIGDVMGAFVAFYLW
                     KAVFDSSQESLIQGFSMADITLYIIMSFVTNLLTRSDSSFMIGEEVKDGSIIMRLLRP
                     VHFAASYLFTELGSKWLIFISVGLPFLSVIVLMKIISGQGIVEVLGLTVLYLFSLTLA
                     YLINFFFNICFGFSAFVFKNLWGSNLLKTSIVAFMSGSLIPLAFFPKVVSDILSFLPF
                     SSLIYTPVMIIVGKYDASQILQALLLQFFWLLVMVGLSQLIWKRVQSFITIQGG"
     gene            2534..3319
                     /locus_tag="VQ862_002091"
     CDS             2534..3319
                     /locus_tag="VQ862_002091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003010202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET3116366.1"
                     /translation="MKKYQRMHLIFIRQYIKQIMEYKVDFVVGVLGVFLAQGLNLLFL
                     NVIFQHIPFLEGWTFQEIAFIYGFSLIPKGMDHLFFDNLWALGQRLVRKGEFDKYLTR
                     PINPLFHILVETFQIDALGELLVGGILLGTTVTSIVWTLPKFLLFLVCIPFATLIYTS
                     LKIATASIAFWTKQSGAMIYIFYMFNDFAKYPISIYNSLLRWLISFIVPFAFTAYYPA
                     SYFLQEKDVFFNVGGLMLISLVFFVISLKLWDKGLDSYESAGS"
     gene            3358..3636
                     /locus_tag="VQ862_002092"
     CDS             3358..3636
                     /locus_tag="VQ862_002092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family acetyltransferase"
                     /protein_id="HET3116367.1"
                     /translation="MFVIEEVKDENQKKAVVAEVLKDLPEWFGIPESTQAYIEGTTTL
                     QVWTAYQESDLTGFVSLSYSSEDCAEIDCLGVKKLIKVEKLGANCLLL"
     gene            3621..3818
                     /locus_tag="VQ862_002093"
     CDS             3621..3818
                     /locus_tag="VQ862_002093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET3116368.1"
                     /translation="MLATLESEARKKVGYLQVKTVAEGSNKDYDRTNDFYRGLGFKKL
                     EIFPQLWNPQNPCQILIKKLE"
BASE COUNT         1171 a          717 c          904 g         1401 t
ORIGIN      
        1 gctatatatt atggtatcga atcttcatca gagtgataaa attaatcaat taatatctga
       61 ttacaaacag aatatgaaag ctttttatat cactattgaa aaatttatac gagatgatga
      121 aagccttaag tgttatttta taaaggttat ttcaagtcgt tccaaggtaa caagtctaga
      181 tcagattgaa gctgataaaa cgatacaaag aaaatattca agtgagctaa aaaaatttat
      241 tggattttat aatgagatta tttgtgagga aaatagtttc ctacatgtac gaaagaggtg
      301 gtcgagttgg tttaggtagt cggtgcgtga gttgataatt ctcagggtat ggacttcttt
      361 ttcatgaatg aggtaaaaga gcaggtattg tttagagaca atcattctga gcatattttc
      421 tggatagagg gagtatccga ttttatgatc aaagttaata ccgccctctg gtgagaagat
      481 gagtaggttg gtaatttaaa ctattaaaca gaatttttga ttaaaagtat tattttatga
      541 gagaaatcct aattttacaa tccataggca aacgcttgca tttcgttttt tattggacta
      601 taataggttg gtataaagcc ttttgtagta ataaaatgta gaaggtgtag aaagtaagga
      661 tttagaatat ttgtagttaa aaacacaatg ttgctattcc ttacgatagg gagatagata
      721 tggcaatgat agaagtggaa catcttcaga aaaattttgt gaagactgtt aaggaaccgg
      781 gcttgaaggg ggctttgcgc tcctttattc atcctgaaaa gcagaccttt gaagcggtca
      841 aggatttgac ctttgaggtt ccaaaagggc agattttagg atttatcggg gcaaatggtg
      901 ctgggaagtc gacaaccatt aaaatgctga caggaatttt gaaaccaaca tctggttttt
      961 gtcggattaa cggcaagatt ccccagaaca atcggcaaga ttatgtcaaa gatattggcg
     1021 tagtctttgg acaacgcacc cagctatggt gggatttggc tctgcaagag acctacactg
     1081 tcttaaaaga gatttatgat gtgccaaact cgctctttca taagcgcatg gactttttga
     1141 atgaagtctt ggatttgaag gactttatca aggatcccgt gcggactctt tcactgggac
     1201 aacggatgcg ggcggatatt gcggcctcct tgctccacaa tcccaaggtt ctttttttag
     1261 atgagccgac cattggtttg gacgtttcgg ttaaggataa tattcgtcgg gcaattactc
     1321 agatcaataa agaggaagaa actaccattc ttttgaccac tcacgatttg agtgatattg
     1381 agcaactttg tgatcggatt ttcatgattg acaaggggca agagattttt gatggaacgg
     1441 tgagccaact caaggagacc tttggtaaga tgaagactct ctcttttgaa ctgctaccag
     1501 gtcaaagtca tctcgtctct cactatgaag gtctgtctga tatgaccatt gatagacaag
     1561 gaaacagcct caacattgaa tttgatagtt ctcgctacca gtcagctgac attatcaagc
     1621 aaaccctatc tgattttgaa atccgcgatt tgaagatggt ggatacggat attgaggata
     1681 ttatccgtcg cttctaccga aaggagctct aggatgatca aattgtggag acgttataaa
     1741 ccctttatca atgcaggggt tcaggagttg attacttacc gagtcaactt tattctctat
     1801 cggattggcg atgtcatggg ggcttttgtg gccttttatc tctggaaggc tgtctttgat
     1861 tcttcgcaag agtctttgat tcagggcttc agtatggcgg atatcaccct ctacatcatc
     1921 atgagttttg tgaccaatct tctgactaga tccgattcgt cctttatgat tggggaggag
     1981 gtcaaggatg gctccattat catgcgtttg ttgcgaccag tgcattttgc ggcctcctat
     2041 cttttcaccg agcttggttc caagtggttg atttttatca gcgttggcct tccattttta
     2101 agtgtcattg tcttgatgaa aatcatatcg ggtcaaggta ttgtagaggt gctaggatta
     2161 actgtccttt atctttttag cttaacgctc gcctatctga ttaacttttt ctttaatatt
     2221 tgctttggat tttcagcctt tgtgtttaaa aatctttggg gttccaacct acttaagact
     2281 tccatagtgg cttttatgtc ggggagtttg attcccttgg cattctttcc aaaggttgtt
     2341 tcagatattc tctccttttt gcctttttca tccttgattt atactccagt tatgatcatt
     2401 gttggaaaat acgatgccag tcagattctt caggcactcc ttttgcagtt cttctggctc
     2461 ttagtgatgg tgggattgtc tcagttgatt tggaaacggg tccagtcctt tatcaccatt
     2521 caaggaggtt agtatgaaaa aatatcaacg aatgcatctg atttttatca gacaatacat
     2581 caaacaaatc atggaatata aggtggattt tgtggttggt gtcttgggag tctttctggc
     2641 tcaaggcttg aatctcttgt ttctcaatgt catctttcaa catattccat tcctagaagg
     2701 ctggaccttt caagagatag ctttcattta tggattttcc ttgattccca agggaatgga
     2761 ccatctcttt tttgacaatc tctgggcact agggcaacgc ctagtccgaa aaggagagtt
     2821 tgacaagtat ctgactcgtc ccatcaatcc tctctttcac atcctagttg aaacctttca
     2881 gattgatgcc ttgggtgaac tcttagtcgg tggtatttta ttgggaacaa cagtgaccag
     2941 cattgtttgg actcttccaa aattcctgct tttcctagtt tgtattcctt ttgcgacctt
     3001 gatttatact tctcttaaaa tcgcaacagc cagtatcgcc ttttggacta agcagtcagg
     3061 cgccatgatt tacatcttct atatgttcaa tgactttgct aagtatccga tttctattta
     3121 caattctctt cttcgttggt tgattagctt tatcgtgcct ttcgccttta cagcctacta
     3181 tccagctagc tatttcttac aggaaaagga tgtgttcttt aacgtaggag gtttgatgtt
     3241 gatttctctg gttttctttg ttatttccct taaactttgg gataagggct tagattccta
     3301 cgaaagtgcg ggttcgtaaa agctaaagta agactaaaat caagaaagaa acttatgatg
     3361 tttgtaattg aagaagtcaa ggatgaaaat caaaaaaagg cagttgtagc tgaggttttg
     3421 aaggatttgc cagaatggtt tggaatccca gaaagcacac aagcctatat agaaggaacc
     3481 acgacactgc aagtttggac cgcctatcag gagagtgatt tgactggatt tgtaagctta
     3541 tcctattcga gtgaagattg tgcagagatt gattgtctcg gcgtaaaaaa gcttatcaag
     3601 gtagaaaaat tgggagccaa ttgcttgcta ctttagagag tgaagctcgt aaaaaagttg
     3661 gttatctgca ggtcaaaaca gtagcagaag gttctaataa agattatgat cgaacaaatg
     3721 acttttatcg aggtcttggc tttaaaaagt tagagatttt tcctcaacta tggaatccgc
     3781 aaaatccttg tcagattttg attaaaaagc ttgaataata ttatttgaca tctattctca
     3841 gagtgctata ctgtaagtgt aatcgccgat ttagctcagt tggtagagca aggcactcgt
     3901 aaagcctagg ttataggtag ataaacgact gaggatttga aaaaatagat aggtagaaga
     3961 taaccgttaa gccttattct tagcggttat ttatattgtt taatagcgct gatatttcat
     4021 caattatgcc tgttttcgtg tttctggtag ttgttcaagt ttattgctac tatttttgat
     4081 ggtatgaatg tgcttataat gtatcccggt taacgaaagt tttggactta tactcttaga
     4141 aaatctcttc aaaccacgtc aacgtcgcct tgccgtgcgt atggttactg act
//
LOCUS       DAVBOD010000100         3984 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 640-05
            SAMEA1012484-rid20186543.denovo.101, whole genome shotgun sequence.
ACCESSION   DAVBOD010000100 DAVBOD010000000
VERSION     DAVBOD010000100.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012484
            Sequence Read Archive: ERR059358
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3984)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3984)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979948.1
            Genome Coverage       :: 595x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:03:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,266
            CDSs (total)                      :: 2,219
            Genes (coding)                    :: 2,091
            CDSs (with protein)               :: 2,091
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 71 of 128
            Pseudo Genes (incomplete)         :: 50 of 128
            Pseudo Genes (internal stop)      :: 33 of 128
            Pseudo Genes (multiple problems)  :: 22 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3984
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012484-rid20186543.denovo.101"
                     /strain="NIG 640-05"
                     /db_xref="taxon:1313"
     gene            complement(382..915)
                     /locus_tag="VQ862_002094"
     CDS             complement(382..915)
                     /locus_tag="VQ862_002094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000775318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF402 domain-containing protein"
                     /protein_id="HET3116369.1"
                     /translation="MKLPKEGDFITIQSYKHDGSLHRTWRDTMVLKTTENAIIGVNDH
                     TLVTESDGRRWVTREPAIVYFHKKYWFNIIAMIRDNGTSYYCNMASPYYLDEEALKYI
                     DYDLDVKIFTDGEKRLLDVEEYERHKRKMNYSDDLDYILKEHVKILVDWINNGRGPFS
                     EAYVNIWYKRYVELKNR"
     gene            complement(1004..1780)
                     /gene="recX"
                     /locus_tag="VQ862_002095"
     CDS             complement(1004..1780)
                     /gene="recX"
                     /locus_tag="VQ862_002095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000705102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination regulator RecX"
                     /protein_id="HET3116370.1"
                     /translation="MKITKLEKKKRLYLMELDGQQTSYITEDTIVRFMLSRDKVISKE
                     ELTEIQDFAQFSYGKNLALYHLSFKARTEKEVREYLKKYDIDKNIVSQVIANLKEDKW
                     INDGQYAYAIINTNQLSGDKGPYVLTQKLAQKGISKSTIEENLKEFDFSEVAQRVANK
                     LLKKYEGKLPSRALQDKIIQNLTNKGFSYSDAKIAFDDLDSQVDQETTQELIFKELDK
                     QYSKYARKYEGYELKQRLTQVLARKGYDFSDIASALREYL"
     gene            complement(1790..2566)
                     /locus_tag="VQ862_002096"
     CDS             complement(1790..2566)
                     /locus_tag="VQ862_002096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001086342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside 3'-phosphotransferase"
                     /protein_id="HET3116371.1"
                     /translation="MNSKTPRFSILDFPEQLRSYIKGANLSDSSSHSSATVLYIDSGY
                     YLKIDQKGRLAQETKIASWFETEGLGTPVITYLSANKDFLLTKEAIGSNALAFLNQPE
                     RLCQTLAQALNKLHSLKPQSFPSENHLKRYKEKALKNYQKGTFYNKTLLPQFHIHSRE
                     EAYQLIQEKGYILKADAFIHGDACLPNFILKDASHFSCFIDLGLAGFSDRHIDLFWAI
                     WSLHYNLQDATYAELFLDYYGREYVNMDKLRLVAAFEAFR"
     gene            2623..3978
                     /gene="rlmD"
                     /locus_tag="VQ862_002097"
     CDS             2623..3978
                     /gene="rlmD"
                     /locus_tag="VQ862_002097"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HET3116372.1"
                     /translation="MNLKVKQKIPLKIKRMGINGEGIGFYQKTLVFVPGALKGEDIYC
                     QITSIRRNFVEAKLLKVNKKSKFRIVPSCTIYNECGGCQIMHLHYDKQLEFKTDLLHQ
                     ALKKFAPAGYENYEIRPTIGMQEPKYYRAKLQFQTRKFKNQVKAGLYAQNSHYLVELK
                     DCLVQDKETQVIANRLAELLTYHQIPITDERKVLGVRTIMVRRARKTGQVQIIIVTNR
                     QLNLTQLVKELVKDFPEVVTVAVNTNTAKTSEIYGEKTEIIWGQESIQEGVLNYEFSL
                     SPRAFYQLNPEQTEVLYSEAVKALDVDKENHLIDAYCGVGTIGFAFAKKVKTLRGMDI
                     IPEAIEDAKRNAKRMGFDNTHYEAGTAEEIIPRWYKEGYRADALIVDPPRTGLDDKLL
                     DTILTYVPEKMVYISCNVSTLARDLVRLVEVYDLHYIQSVDMFPHTARTEAVVKLIKK
                     V"
BASE COUNT         1266 a          698 c          745 g         1275 t
ORIGIN      
        1 atttcatttt actatactat tacgaaatta gatatataaa tgaaaacttg cctcaaggta
       61 ggtttttttg ctagtagaaa agcgatagac agaaattgtt ggactcttaa aaaaatgaag
      121 ttttgctcaa aagagcttct taaattaaaa cgagcaatta tcagttcaaa tctgtttcaa
      181 aagaagaacg gataaattaa tcgatgcttt gtttttgagt taggaagtta agcatgccaa
      241 actgagtcgt aggaataaat ctctttctag taatgtgttg taactctgct ataatggatt
      301 tattcctttt tgtgtttaca caatttattt tatactacca aaaaaacaag gtcaggattt
      361 tgttcctgac ctttgacaac tttaccgatt ctttagttct acatagcgct tgtaccaaat
      421 gtttacatag gcttctgaga aaggaccacg tccattgtta atccaatcaa caagaatttt
      481 gacatgttct tttaaaatat agtccaagtc atcagaataa ttcattttgc gtttgtgacg
      541 ctcgtactct tcaacgtcca agagacgttt ttccccatct gtaaaaattt taacatccaa
      601 atcgtaatca atatacttca gtgcttcttc atccagatag taggggctag ccatattgca
      661 atagtaagaa gttccattat cacgaatcat ggcaatgata ttaaaccaat atttcttgtg
      721 aaagtaaaca atagccggtt ctcgagtgac ccaacgacga ccatcacttt cggtaacaag
      781 tgtatgatcg ttgacaccaa taatggcgtt ttctgttgtt tttagtacca tggtgtcccg
      841 ccaagttcgg tggagactcc catcatgctt ataactttga attgtaataa agtcgccttc
      901 ttttggaagc ttcataacta accaactttc tacaatttat aagtttatca tttactattg
      961 taccataaaa ttacctaaaa tctgtgaatt tcacttggaa atattaaaga tattctctaa
     1021 gagcgcttgc tatatccgaa aaatcgtagc cctttcgtgc taaaacttga gttaaacgct
     1081 gcttcagttc gtatccttca tactttcgag catacttact atattgttta tcaagttcct
     1141 tgaagatgag ttcttgagtc gtttcttggt caacttggct atctaagtcg tcaaaggcaa
     1201 ttttagcatc agaataagag aagcccttgt tagtcaagtt ctggataatc ttatcttgca
     1261 gggcacgaga tggaagtttt ccctcatatt ttttcaatag tttattagct acacgttgag
     1321 caacttcaga aaaatcaaat tctttcaagt tctcttctat agtagatttt gaaatccctt
     1381 tttgagctag tttctgagtc agcacataag gacccttgtc tcctgaaagt tgattggtat
     1441 tgatgatagc ataagcgtac tgaccatcat taatccactt atcttcttta agattagcaa
     1501 taacttgaga aacgatgttt ttatcaatat cgtatttttt cagatattct ctgacttctt
     1561 tttcagtgcg tgctttaaag gataagtggt agagagcgag attcttacca taagaaaact
     1621 gggcaaaatc ctgaatctcg gtcagttcct ctttactaat gaccttatct cgagacagca
     1681 taaaacggac aatggtatct tccgtgatat aagaggtttg ctgtccatct agttccatca
     1741 agtagagacg ttttttcttt tcaagttttg tgattttcat aatttccttt catctaaatg
     1801 cttcgaaagc tgcaacaagt cgtagtttat ccatatttac atattctcta ccgtaatagt
     1861 cgagaaataa ttcagcatac gtagcatctt gtaggttgta atgaagggac caaattgccc
     1921 aaaagaggtc gatatgtcgg tcactaaaac cagccaatcc caagtcaata aagcaagaaa
     1981 aatgagaggc atccttcaag atgaaatttg gcaggcaggc atctccatga ataaaagcat
     2041 cagctttgag aatgtaacct ttctcttgta tcagttggta agcttcttca cgactgtgaa
     2101 tgtgaaattg aggcagaaga gtcttgttat aaaaagtccc cttctgatag ttttttaagg
     2161 ctttttcttt ataacgcttc agatgatttt ccgacggaaa agattgtggt ttaagactgt
     2221 gaagtttgtt taatgcttga gccagggttt gacagagtct ttcgggttga tttaaaaaag
     2281 cgagagcgtt gctgccaatg gcttctttag tcagaaggaa gtccttattt gctgataaat
     2341 aggtaatcac tggagttccc aatccttcag tttcgaacca acttgcaatc ttagtttctt
     2401 gagctaatct gcctttttga tctattttta aatagtaacc tgaatctata tataggacag
     2461 ttgcacttga atgagaagaa ctatcagaga gattagctcc cttgatatag cttcgtaatt
     2521 gttcagggaa atctagtata ctaaagcgag gtgtttttga attcatgctt ttattgtaac
     2581 atattcttaa atatcttaga aactccatgg tataatagac atatgaatct gaaagtgaaa
     2641 caaaaaatac cattaaaaat caagcgcatg ggaattaacg gtgagggaat cggcttttac
     2701 caaaaaacat tagtctttgt accaggagct ctcaaaggcg aagatatcta ttgtcagatt
     2761 acttctatta gacgcaactt tgttgaagca aaattactga aggtcaacaa gaagtctaaa
     2821 tttcgaattg tgccatcttg tactatttat aatgaatgcg gaggctgcca aatcatgcac
     2881 ctgcattatg ataagcagct ggagttcaag acggacttac ttcatcaagc gctgaaaaaa
     2941 tttgctcctg caggatatga aaattatgaa attcgtccaa ctattggaat gcaggaacca
     3001 aaatattaca gagctaagtt acaatttcag actcgaaaat ttaaaaatca ggtcaaggcg
     3061 ggcttatatg cacaaaactc tcactattta gtagagttga aagactgcct ggtacaagat
     3121 aaggaaaccc aagtgattgc taatcgctta gcagaattac ttacttatca ccagattcca
     3181 atcacggatg agagaaaagt tctaggtgtc cgtactatta tggtccgacg cgcgagaaag
     3241 accggacagg ttcagattat tattgttaca aaccgccagc ttaatttaac tcaattggta
     3301 aaagagttgg ttaaagattt cccagaagtt gtgacagtag ctgttaatac aaatacagct
     3361 aaaaccagtg agatatatgg tgaaaagaca gagattatct gggggcaaga gagtattcaa
     3421 gaaggtgtac tcaattatga attttcacta tcccctcgag ctttttatca actaaatcct
     3481 gagcaaacag aagtcctcta tagcgaagca gtaaaagcgc tggatgttga taaagaaaac
     3541 catttgattg acgcttattg tggagttgga acgattggat ttgcctttgc aaagaaagta
     3601 aaaacactca gaggtatgga tattattcca gaagctattg aagatgccaa gcgaaatgct
     3661 aaaagaatgg gatttgacaa tactcattat gaagctggaa cggcagaaga gattattcct
     3721 cgttggtaca aggaaggcta ccgagcagat gctttgattg ttgacccacc acgtacaggt
     3781 ctggatgata agttattaga tactattctt acttatgtac cagaaaaaat ggtttatatt
     3841 tcttgtaatg tttcgacctt ggctcgtgat ttggtacgct tagtagaagt ctatgatctt
     3901 cattatatcc agtcggtcga tatgttccca catacagctc gaactgaagc tgttgtaaaa
     3961 ttaataaaaa aagtttaaaa aagg
//
LOCUS       DAVBOD010000101         3893 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 640-05
            SAMEA1012484-rid20186543.denovo.102, whole genome shotgun sequence.
ACCESSION   DAVBOD010000101 DAVBOD010000000
VERSION     DAVBOD010000101.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012484
            Sequence Read Archive: ERR059358
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3893)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3893)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979948.1
            Genome Coverage       :: 595x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:03:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,266
            CDSs (total)                      :: 2,219
            Genes (coding)                    :: 2,091
            CDSs (with protein)               :: 2,091
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 71 of 128
            Pseudo Genes (incomplete)         :: 50 of 128
            Pseudo Genes (internal stop)      :: 33 of 128
            Pseudo Genes (multiple problems)  :: 22 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3893
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012484-rid20186543.denovo.102"
                     /strain="NIG 640-05"
                     /db_xref="taxon:1313"
     gene            complement(112..1782)
                     /locus_tag="VQ862_002098"
     CDS             complement(112..1782)
                     /locus_tag="VQ862_002098"
                     /EC_number="6.3.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019803354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate--tetrahydrofolate ligase"
                     /protein_id="HET3116373.1"
                     /translation="MKTDIEIAQSIELKPIVDVVEKLGISYDDLELYGKYKAKLSFDK
                     IRAVESNPVGKLILVTAINPTPAGEGKSTLTIGLADALNKIGKKTMIAIREPSLGPVM
                     GIKGGAAGGGYAQVLPMEDINLHFTGDMHAITTANNALSALIDNHLHQGNELGIDQRR
                     ILWKRVVDLNDRALRHVTVGLGGPLNGIPREDGFDITVASEIMAILCLATDIEDLKRR
                     LANIVIGYRYDRTPVSVGDLQVEGALALILKDAIKPNLVQTIYGTPAFVHGGPFANIA
                     HGCNSVLATTTALHLADYTVTEAGFGADLGAEKFLDIKTPNLPTSPDAVVIVATLRAL
                     KMNGGVAKDALTEENVEAVRAGFANLKRHVENIRKFGIPAVVAINEFVSDTEAEIAVL
                     KELCASIDVPVELASVWADGAEGGVALAETVVKTIAENPANYKRLYDNDLSVQEKIEK
                     IVTEIYRGSKVNFEKKAQTQIAQIVQNGWDKLPICMAKTQYSFSDNPNALGAPENFEI
                     TIRELVPKLGAGFIVALTGDVMTMPGLPKRPAALNMDVESDGTVLGLF"
     gene            2012..2701
                     /gene="coaB"
                     /locus_tag="VQ862_002099"
     CDS             2012..2701
                     /gene="coaB"
                     /locus_tag="VQ862_002099"
                     /EC_number="6.3.2.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000699493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenate--cysteine ligase"
                     /protein_id="HET3116374.1"
                     /translation="MKILVTSGGTSEAIDSVRSITNHSTGHLGKIITETLLSAGHEVC
                     LITTKRALKPEPHPNLSIREITNTKDLLIEMQERVQDYQVLIHSMAVSDYTPVYMTGL
                     EEVQASSNLKEFLSKQNHQAKISSTDEVQVLFLKKTPKIISLVKEWNPTIHLIGFKLL
                     VDVTEDHLVDIARKSLIKNQADLIIANDLTQISADQHRAIFVEKNQLQTVQTKEEIAE
                     LLLEKIQAYHS"
     gene            2713..3264
                     /gene="coaC"
                     /locus_tag="VQ862_002100"
     CDS             2713..3264
                     /gene="coaC"
                     /locus_tag="VQ862_002100"
                     /EC_number="4.1.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenoylcysteine decarboxylase"
                     /protein_id="HET3116375.1"
                     /translation="MANILLAVTGSIASYKSADLVSSLKKQGHQVTVLMTQAATEFIQ
                     PLTLQVLSQNPVHLDVMKEPYPDQVNHIELGKKADLFIVVPATANTIAKLAHGFADNM
                     VTSTALALPSHIPKLIAPAMNTKMYDHPVTQNNLKTLETYGYQLIAPKESLLACGDHG
                     RGALADLTIILERIKETLDEKTL"
     gene            3248..3811
                     /locus_tag="VQ862_002101"
     CDS             3248..3811
                     /locus_tag="VQ862_002101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000747407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HET3116376.1"
                     /translation="MKKRSNIAPIAIFFATMLVIHFLSSLIFNLFPFPIKPTIVHIPV
                     IIASIIYGPRVGVTLGFLMGLLSLTVNTITILPTSYLFSPFVPNGNIYSAIIAIVPRI
                     LIGLTPYLVYKLMKNKTGLILAGALGSLTNTIFVLGGIFFLFGNVYNGNIQLLLATVI
                     STNSIAELVISAILTLAIVPRLQTLKK"
BASE COUNT         1171 a          874 c          693 g         1155 t
ORIGIN      
        1 gtttgaaaag attttcgaag agtataaatc ttattgatga actgcttgca gtctgagaaa
       61 aaatgagctt ggatattatt tccaaactca cttaaagtca atttcaatcc actagaacaa
      121 gcctagcaca gttccatcgc tttcaacatc catgttgaga gctgctggac gttttggaag
      181 acctggcatg gtcataacat caccagttaa ggcaacgatg aagcctgcac ctaattttgg
      241 taccaattca cgaatggtaa tttcaaagtt ttctggtgct ccaagcgcat ttggattgtc
      301 tgagaaactg tattgagttt tagccataca aattggcaat ttgtcccaac cgttttgaac
      361 gatttgagca atttgtgttt gagctttctt ctcaaagttc actttgctac cacgatagat
      421 ttcagtgaca attttttcaa tcttttcttg gacagaaaga tcattatcgt acaaacgttt
      481 atagttagct ggattttcag caattgtctt aacaactgtt tcggcaagtg ctactccacc
      541 ttctgctcca tcagcccaga cactagccaa ttcaactggt acatcgattg aggcacagag
      601 ttcttttaag actgcaattt cagcttctgt atcagataca aattcgttaa tagctacaac
      661 tgctggaata ccgaacttac ggatattttc aacgtggcgt ttcaagttag caaaacctgc
      721 acgaactgcc tctacatttt cttcagtcag agcgtcttta gccacaccac cattcatctt
      781 aagggcacga agggttgcga caataacaac tgcatctgga gatgttggca agtttggtgt
      841 cttgatatca aggaatttct cagcaccaag atccgcacca aaaccagctt cagtaacagt
      901 gtaatcagcc aagtgaaggg ctgttgtcgt cgccaaaaca gagttacagc catgagcgat
      961 attggcaaat ggaccaccgt gtacaaaggc aggtgtaccg taaattgtct gaaccaagtt
     1021 tggcttaata gcatccttca aaatcaaagc caaggcaccc tcaacctgca aatcacctac
     1081 agaaacaggc gtacggtcat agcgataacc aataacgata ttcgccaaac gacgtttcaa
     1141 gtcctcgatg tccgttgcca agcaaagaat tgccatgatt tctgaagcaa ctgtaatatc
     1201 aaaaccgtcc tcacgtggaa taccgtttag aggaccacca agaccaacag tcacatggcg
     1261 gagcgcacgg tcgttcaagt ccacaacgcg tttccagagg atacgacgtt gatcaattcc
     1321 cagctcattc ccttggtgca agtggttgtc aatcaaggca gaaagggcat tgttggcagt
     1381 tgtaatagca tgcatatctc cagtaaagtg gaggttgatg tcttccattg gcagaacttg
     1441 tgcataccca ccaccagcag caccaccctt gatccccatg actggaccaa gagacggttc
     1501 gcggatagca atcatggttt tcttgccaat cttgttcaag gcatccgcaa gaccaatggt
     1561 aagcgtcgac tttccttcac ctgcaggtgt tgggttgatg gcagtaacca agatcaattt
     1621 accgactgga ttgctctcaa ctgcacgaat tttatcaaag ctgagtttag ccttgtactt
     1681 tccgtacaac tccaaatcgt cataagaaat accaagtttc tctacaacat caacaattgg
     1741 cttcaactca atactctgtg cgatttcaat atctgttttc attcaaaatt cctctaacct
     1801 cttatatgat aattcattat atcacaaaac aagattttta acatcctaaa actctctaaa
     1861 cgttcgtaaa tatctctgtt tttaagactt ttagagtcct ttcttaaatt ttatatggct
     1921 ttatagtttg aaactataat aaatcttcgt ttttaccaaa aatttatcac tttcatttta
     1981 cttaccgctt atttttgtgt acaatagtgc tatgaaaatt ttagttacat cgggcggtac
     2041 cagtgaagct atcgatagcg tccgctctat cactaaccat tctacaggtc acttggggaa
     2101 aattatcaca gagactttgc tttctgcagg gcatgaagtt tgtttaatta cgacaaaacg
     2161 agctctgaag ccagagcctc atcctaacct aagtattcga gaaattacca ataccaagga
     2221 ccttctaata gaaatgcaag aacgtgttca ggattatcag gtcttgatcc actcaatggc
     2281 tgtttctgac tacactcctg tttatatgac agggcttgag gaagttcagg ctagctccaa
     2341 tctaaaagaa tttttaagca agcagaatca tcaggccaag atttcttcaa ctgatgaggt
     2401 tcaggttttg ttccttaaaa agacacccaa aatcatatcc ctagtcaagg aatggaatcc
     2461 tactattcat ctgattggtt tcaaactgct ggttgatgtt accgaagatc atctggttga
     2521 cattgcacga aaaagtctta tcaagaatca agcagattta atcatcgcga atgacctgac
     2581 tcaaatttca gcagatcagc accgagctat atttgttgag aaaaatcagc ttcaaacagt
     2641 ccagactaaa gaagaaattg cagaactcct ccttgaaaaa attcaagcct atcattctta
     2701 gaaaggaaaa ctatggcaaa cattctcttg gctgtaacgg gttcaatcgc ctcttataag
     2761 tcggcagatt tagtcagttc tctaaaaaaa caaggccatc aagtcactgt cttaatgact
     2821 caggctgcta cagagtttat ccaacctttg acactacagg tactctcaca gaatcctgtc
     2881 cacttggatg tcatgaagga accctatcct gatcaggtca atcatatcga acttggaaaa
     2941 aaagcagatt tatttatcgt ggtacctgca actgctaaca ctattgcaaa actagctcac
     3001 ggatttgcgg acaacatggt aaccagtaca gctctagccc taccaagtca tattcccaaa
     3061 ctaatagctc ctgctatgaa tacaaaaatg tatgaccatc cagtaactca gaataatctg
     3121 aaaacattag aaacctacgg ctatcagctg attgctccta aggaatccct actagcttgt
     3181 ggagaccacg gacgaggagc tttagctgac ctcacaatta ttttagaaag aataaaggaa
     3241 actctcgatg aaaaaacgct ctaatattgc acccattgct atcttttttg ctaccatgct
     3301 cgtgatacac tttctgagct cacttatctt taaccttttt ccatttccaa tcaaaccgac
     3361 cattgttcat attcctgtca ttattgccag cattatttat ggtccacgag ttggggttac
     3421 acttggattt ttgatgggat tacttagctt gacggttaac acgattacga ttctaccgac
     3481 aagctacctc ttctctccct tcgtaccaaa cggaaacatc tactcagcta tcattgccat
     3541 tgtcccacgt attttgattg gtttaactcc ttacttagtc tataaactga tgaaaaacaa
     3601 gactggtctg attttagctg gggctcttgg ttccttgaca aatactatct ttgtccttgg
     3661 aggaatcttc ttcctatttg gaaatgttta taatggaaat atccaacttc ttctggcaac
     3721 cgttatctca acaaattcaa ttgctgaatt ggtcatttct gcaattctaa ccctagccat
     3781 tgttccacga ctacaaacct tgaaaaaata aaaacaatct ccgctttcaa acctgaaggt
     3841 ggagattttg ctctatacag tttcttttta atgaaatctt tactatagta aaa
//
LOCUS       DAVBOD010000102         3609 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 640-05
            SAMEA1012484-rid20186543.denovo.103, whole genome shotgun sequence.
ACCESSION   DAVBOD010000102 DAVBOD010000000
VERSION     DAVBOD010000102.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012484
            Sequence Read Archive: ERR059358
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3609)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3609)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979948.1
            Genome Coverage       :: 595x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:03:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,266
            CDSs (total)                      :: 2,219
            Genes (coding)                    :: 2,091
            CDSs (with protein)               :: 2,091
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 71 of 128
            Pseudo Genes (incomplete)         :: 50 of 128
            Pseudo Genes (internal stop)      :: 33 of 128
            Pseudo Genes (multiple problems)  :: 22 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3609
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012484-rid20186543.denovo.103"
                     /strain="NIG 640-05"
                     /db_xref="taxon:1313"
     gene            320..1666
                     /gene="gdhA"
                     /locus_tag="VQ862_002102"
     CDS             320..1666
                     /gene="gdhA"
                     /locus_tag="VQ862_002102"
                     /EC_number="1.4.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001858584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-specific glutamate dehydrogenase"
                     /protein_id="HET3116377.1"
                     /translation="MTSAKEYIQSVFETVKARNGHEAEFLQAVEEFFNTLEPVFEKHP
                     EYIEENILARITEPERVVSFRVPWVDRDGKIQVNRGYRVQFNSAVGPYKGGLRFHPTV
                     NQGILKFLGFEQIFKNVLTGLPIGGGKGGSDFDPKGKTDAEVMRFCQSFMTELQKHIG
                     PSLDVPAGDIGVGGREIGYLYGQYKRLNQFDAGVLTGKPLGFGGSLIRPEATGYGLVY
                     YTEEMLKANGNSFAGKKVVISGSGNVAQYALQKATELGATVISVSDSNGYVIDENGID
                     FDLLVDVKEKRRARLTEYAAEKATATYHEGTVWTYAGNYDIALPCATQNEINGEAAKR
                     LVAQGIICVSEGANMPSDLDAIKVYKENGILYGPAKAANAGGVAVSALEMSQNSLRLS
                     WTREEVDDRLKDIMTNIFNTAKTTSETYGLDKDYLAGANIAAFENVANAMIAQGIV"
     gene            complement(2162..2332)
                     /locus_tag="VQ862_002103"
     CDS             complement(2162..2332)
                     /locus_tag="VQ862_002103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3116378.1"
                     /translation="MKKENEYVILTTASLGVMIGIVFAIFLDFPVEYGISLGLLNGIV
                     LGSLIVYKNNKN"
     gene            complement(2345..2986)
                     /locus_tag="VQ862_002104"
     CDS             complement(2345..2986)
                     /locus_tag="VQ862_002104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HET3116379.1"
                     /translation="MTIESGQRIALVGQPGSGKSTLSKIPSGLYKIDTGKVLFDGVNI
                     NQIDKKILSQNLGVVPQDSFLLNRSILDNITLKHEVTSQKIEEVCKAVQIYDEIMAMP
                     MKFNTIISEMGSNISGGQRQRIALARALINNPSIVILDEATSALDTINEERITKYIKS
                     QGCTQIIVAHRLSTIKDADIIVVMKGGKIVESGNHKYLMDLGGEYYSLYTKRK"
BASE COUNT         1120 a          704 c          590 g         1195 t
ORIGIN      
        1 cttttttatt ttagtctagt ctaaatattg cttttctcca aaatggtcat agttttactg
       61 gcaaatctaa catatcacgg ataaattaac aagtgatttc tgaattgcta aacattttct
      121 tttcttatag catactttaa gattttgtct ttgagaaaga tatttccaag aaaaacgttc
      181 gtttttttat ctattttcaa aaaaaccaaa aaactgaatt gaaagaattt ttagaaaatt
      241 tctgtttttt ctttacagtg aaaaaaaatt ctgctataat gtcttatgta ataaaatatg
      301 acaataaaag gagaacgata tgacatctgc taaagaatat atccaaagcg tgtttgaaac
      361 tgtgaaagct cgtaacgggc acgaggctga attcctccaa gctgttgaag aatttttcaa
      421 cactttagaa cctgtatttg aaaaacaccc tgagtatatc gaagaaaata tcttggcacg
      481 tattactgag cctgagcgcg tggtttcttt ccgtgttcct tgggttgacc gtgatggaaa
      541 aattcaagta aaccgtggtt accgtgttca attcaactca gctgttggac catacaaagg
      601 tggacttcgt ttccacccaa ctgtaaacca agggatcttg aaattcctcg gatttgaaca
      661 aatctttaaa aatgtcttga ctggacttcc tatcggtgga ggtaaaggtg gatcagactt
      721 cgatcctaaa ggtaaaacag atgctgaagt gatgcgcttc tgccaaagct tcatgactga
      781 attgcaaaaa cacatcggac catcacttga cgtacctgct ggtgatatcg gtgttggtgg
      841 acgtgaaatt ggttaccttt acggtcaata caaacgtctt aaccaatttg atgctggtgt
      901 cttgactggt aaacctcttg gatttggtgg tagcttgatt cgtccagaag caactggtta
      961 cggtttggtt tactatactg aagaaatgct caaagctaac ggtaacagct ttgctggtaa
     1021 gaaagtcgtt atttcaggtt ctggtaacgt tgctcaatat gctcttcaaa aagcaactga
     1081 actcggtgca actgttattt ctgtttctga ctcaaatggt tatgtcatcg atgaaaatgg
     1141 tatcgacttc gatcttttgg ttgatgttaa agaaaaacgt cgtgctcgtt tgactgagta
     1201 tgcagctgaa aaagcaactg caacctacca cgaaggtact gtatggactt acgctggaaa
     1261 ctatgacatt gctcttccat gtgccactca aaacgaaatc aacggtgaag cagctaaacg
     1321 tttggttgct caaggcatta tctgtgtatc tgaaggtgcc aacatgccga gcgaccttga
     1381 tgccatcaaa gtttacaaag aaaatggtat cttatacgga cctgcaaaag ctgccaacgc
     1441 tggtggtgta gccgtttcag ctcttgaaat gagccaaaac agtcttcgcc tctcatggac
     1501 tcgtgaagaa gttgatgacc gtctcaaaga catcatgaca aacatcttca acacagctaa
     1561 aacgacttca gaaacatacg gtcttgataa agactacctt gcaggagcta acattgctgc
     1621 ctttgaaaat gtagcaaacg ctatgattgc ccaaggtatt gtttaagatt tatttgctta
     1681 atcctcaatc actacgattg gggattttta gttgagttag acagttggga aattctaatt
     1741 aaatgaaata aaaactgaac aaattgattg cggaattcaa accaatttct aacatatttc
     1801 tagaaattaa tttgactttt ctaatcgatt tgttcatatc ttatttcaat ttactatact
     1861 tacttaaccc tttttatact caatgaaaat caaagagcaa actaggaagc gagtcgcagg
     1921 ctgtacttga gtacggcaag gcaaagctga cgtggtttga agagattttc aaagagtatt
     1981 aaacaaaaag aaaaaacgct actcctaaga atagcgattt aatcatgttt ttaagctact
     2041 actgtagttg ctctattatt taagtgttat gaataacttc aatatcttta aagctttttg
     2101 ttagatttat aatttcaact atagccatct ctactcctta gtttacagca aaaaattatg
     2161 cttaattctt attgtttttg taaacaatca gcgaacccaa tactattcca ttcaacaatc
     2221 ctaaagaaat accatattca actggaaaat ctaaaaaaat tgcaaacact attccaatca
     2281 tcacccctag tgaggctgtt gttaaaatta catattcatt ttctttcttc attttcttta
     2341 cacctcattt cctttttgta tataagctgt agtactctcc accaagatcc attaagtact
     2401 tatgatttcc tgactcaaca atcttaccac ctttcattac aacaataata tccgcatcct
     2461 taatcgttga caatctatga gctacaatta tttgagtaca gccctgactt tttatatact
     2521 ttgttattct ttcctcatta atagtgtcta aagcactagt tgcttcatct aaaattacaa
     2581 tactaggatt atttattaat gcacgtgcca gtgctatccg ttgtctttga ccacctgaaa
     2641 tatttgaacc catctctgag atgatagtat taaatttcat cggcatagcc atgatttcat
     2701 catagatttg aactgcttta caaacttcct ctatcttttg tgaagtaact tcgtgcttta
     2761 aagttatgtt atcaagaata cttctgttca ataaaaacga atcctgtgga actactccta
     2821 aattttgact taatattttt ttatctattt gattaatatt tacaccatca aataaaactt
     2881 ttcctgtatc aatcttatat aatcctgatg gtatttttga taatgtactt tttcctgacc
     2941 ccggttgacc gactagtgca attctctgtc ctgactcaat agtcaaattt aaattttcta
     3001 ttacaagagc tgagtctttg gaataagaga aagataggtc cttaatatct attctacttc
     3061 aaacgtttct aaactatact ccggaaaata atttaaccaa taactatctt tcatcgtatc
     3121 ctccaaccag tactaagagt ctgggacaat agtctcttat ctccaaaaaa gaagcggatt
     3181 tgccgttgct tttttgcatg gttgcgatag tcttggtaaa atagaattgc ccaataaacc
     3241 atttagaagg gctatcccat gcatattcac tataacacaa atcaaacaac tttaccacta
     3301 gaaatcagtt ctttcttgcc gcaagaccat ctcgtcttta ctattgaaaa agtggtgaat
     3361 accgatgaaa aggaggtaaa ccatctgatt aaacccaaat cattcatacc tctctcaact
     3421 agatgtaact tacaaaaccc ctgacctcat gagccacttt cttcctcctc atgaggtcag
     3481 ttttactttc tgctgttcca gtatcgtttt tcctcgctag atttcctcaa aagggcagac
     3541 tcctcccttg gtgcgtcaca tgattttttc atctcgactg ttctttaatg catcattaac
     3601 gacgctttt
//
LOCUS       DAVBOD010000103         3466 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 640-05
            SAMEA1012484-rid20186543.denovo.104, whole genome shotgun sequence.
ACCESSION   DAVBOD010000103 DAVBOD010000000
VERSION     DAVBOD010000103.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012484
            Sequence Read Archive: ERR059358
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3466)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3466)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979948.1
            Genome Coverage       :: 595x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:03:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,266
            CDSs (total)                      :: 2,219
            Genes (coding)                    :: 2,091
            CDSs (with protein)               :: 2,091
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 71 of 128
            Pseudo Genes (incomplete)         :: 50 of 128
            Pseudo Genes (internal stop)      :: 33 of 128
            Pseudo Genes (multiple problems)  :: 22 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3466
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012484-rid20186543.denovo.104"
                     /strain="NIG 640-05"
                     /db_xref="taxon:1313"
     gene            complement(180..791)
                     /gene="rpsD"
                     /locus_tag="VQ862_002105"
     CDS             complement(180..791)
                     /gene="rpsD"
                     /locus_tag="VQ862_002105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S4"
                     /protein_id="HET3116380.1"
                     /translation="MSRYTGPSWKQARRLGLSLTGTGKELARRNYVPGQHGPNNRSKL
                     SEYGLQLAEKQKLRFTYGVGEKQFRNLFVQATKIKGGILGFNFMLLLERRLDNVVYRL
                     GLATTRRQARQFVNHGHILVDGKRVDIPSYRVTPGQVISVREKSLKVPAILEAVEATL
                     GRPAFVSFDAEKLEGSLTRLPERDEINPEINEALVVEFYNKML"
     gene            complement(986..2038)
                     /locus_tag="VQ862_002106"
     CDS             complement(986..2038)
                     /locus_tag="VQ862_002106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000769768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HET3116381.1"
                     /translation="MKLKSYILVGYIISTLLTILVVFWAVQKMLIAKGEIYFLLGMTI
                     VASLVGAGISLFLLLPVFTSLGKLKEHAKRVAAKDFPSNLEVQGPVEFQQLGQTFNEM
                     SHDLQVSFDSLEESEREKGLMIAQLSHDIKTPITSIQATVEGILDGIIKESEQAHYLA
                     TIGRQTERLNKLVEELNFLTLNTARNQVETTSKDSIFLDKLLIECMSEFQFLIEQERR
                     DVHLQVIPESARIEGDYAKLSRILVNLVDNAFKYSAPGTKLEVVAKLEKDQLSISVTD
                     EGQGIAPEDLENIFKRLYRVETSRNMKTGGHGLGLAIARELAHQLGGEITVSSQYGLG
                     STFTLVLNLSGSENKA"
     gene            complement(2035..2733)
                     /locus_tag="VQ862_002107"
     CDS             complement(2035..2733)
                     /locus_tag="VQ862_002107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000520636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET3116382.1"
                     /translation="MGKTILLVDDEVEITDIHQRYLIQAGYQVLVAHDGLEALELFKK
                     KPIDLIITDVMMPRMDGYDLISEVQYLSPEQPFLFITAKTSEQDKIYGLSLGADDFIA
                     KPFSPRELVLRVHNILRRLHRGGETELISLGNLKMNHSSHEVQIGEEMLDLTVKSFEL
                     LWILASNPERVFSKTDLYEKIWKEDYVDDTNTLNVHIHALRQELAKYSSDQTPTIKTV
                     WGLGYKIEKPRGQT"
     gene            complement(2900..>3466)
                     /locus_tag="VQ862_002108"
     CDS             complement(2900..>3466)
                     /locus_tag="VQ862_002108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin-binding SSURE repeat-containing
                     protein"
                     /protein_id="HET3116383.1"
                     /translation="DAKNPALSPLGENVKTKGQYFYQVALDGNVAGKEKQALIDQFRA
                     NGTQTYSATVNVYGNKDGKPDLDNIVATKKVTIKINVKETSDTANGSLSPSNSGSGVT
                     PMNHNHATGTTDSMPADTMTSSTNTMAGENMAASANKMSDTMMSEDKAMLPNTGETQT
                     SMASIGLLGLALAGLLGGLGLKNKKEEN"
BASE COUNT          945 a          779 c          674 g         1068 t
ORIGIN      
        1 attataccac attgtgtact atttttggtt cattttacta tatcactttg gactatatcg
       61 gtctagttat gtctcaacga ttatagctgg atactaagag aaatcaaaaa agcactaagg
      121 gagaacgtcc caaagtgctt aatatcaagg cctcaaagcc tgtcttattc aataaaatat
      181 tacaacatct tgttgtagaa ttcaacgaca agtgcttcgt tgatttctgg gttgatttcg
      241 tcgcgttctg gcaagcgagt caatgaacct tccaactttt cagcgtcgaa tgatacgaat
      301 gctggacgtc caagagtagc ttctactgct tcaaggattg ctggaacttt caatgatttt
      361 tcacgaactg agatcacttg acctggagtt acgcggtatg atgggatatc aacgcgtttc
      421 ccgtcaacaa ggatgtgacc gtggtttacg aattgacgag cttgacgacg agtagtcgcg
      481 agaccaagac ggtaaacaac attatccaaa cgacgttcca aaagaagcat aaagttgaaa
      541 cctaggattc cacctttgat ttttgtagct tgtacgaaca agttacggaa ttgtttttca
      601 cctacaccgt aagtgaaacg aagtttttgt ttttcagcca attgcaaacc gtattctgac
      661 aatttagaac ggttgtttgg tccgtgttgt cctggtacgt agttacgacg tgccaattct
      721 ttacctgtac ctgtaagtga aaggccaagg cgacgagctt gtttccaaga tggtcctgta
      781 taacgtgaca tatgaatgtc ctcctgatat aaataatatt tcggtggaaa tagtcactta
      841 gaaagccctg attcgtgcag atgcccttcg cctaaacagc caaggttact tatcataaga
      901 cacctgttga cgagcttcat gctttcctgc tgatatttca cacaaaatcc attctaccat
      961 gaatagctgg atttgtaaag gggttttagg ctttattttc actaccagag aggttgagaa
     1021 cgagggtaaa ggtacttcct agaccgtact ggctgctgac tgtgatttcc ccacccaatt
     1081 gatgggccaa ttcacgcgca atcgcaagtc ctaatccatg accacctgtc ttcatgttac
     1141 gcgaagtttc gacacgataa aggcgtttga aaatattttc caaatcctct ggggcaatgc
     1201 cctgcccttc atcggtcaca ctgattgaaa gctggtcctt ctccagctta gccaccactt
     1261 ccagcttggt tcctggagca gaatatttaa aagcgttatc gaccagattc accaagatac
     1321 gagaaagctt agcataatct ccctcaatcc gggcagactc tgggattacc tgcaagtgga
     1381 catctcttct ctcctgctca atcaaaaact gaaattcact catgcactca attaagagct
     1441 tgtccagaaa aatactgtct ttactggtag tttccacctg atttctagct gtgtttaggg
     1501 tcaaaaaatt caactcctca accagtttat tgagcctctc cgtctggcgt ccaatggttg
     1561 ctagataatg agcttgctcc gactccttga taatcccatc caaaatccct tctaccgtcg
     1621 cttggatcga agtgatagga gtcttaatat catgcgacaa ctgagcaatc atcaagccct
     1681 tttctcgttc gctttcttcc aaggaatcaa agcttacctg caaatcatgg gacatctcat
     1741 taaaagtttg ccctaattgc tgaaattcta caggaccttg aacctccaaa tttgaaggaa
     1801 aatccttggc cgctacccgc ttggcatgct ccttgagttt gcccaacgac gtaaagactg
     1861 gcaataggag aaagagacta atcccagcac cgacaaggct ggcaacgatg gtcatcccaa
     1921 gcaaaaagta aatctcgcct ttcgcaatca gcattttttg aacagcccaa aaaacaacca
     1981 aaatggttaa gagggttgaa ataatatatc caaccaaaat ataacttttt agtttcatgt
     2041 ttgtcctctc ggtttctcta tcttatatcc caacccccaa actgtcttaa tagtgggcgt
     2101 ttggtcacta ctatattttg ccagctcctg tcgaagagca tggatatgca cattcaaggt
     2161 attggtgtca tccacgtagt cttctttcca gatcttttca tagaggtctg tcttggagaa
     2221 aactcgctct ggattgctag ctaaaatcca cagcaattca aatgatttaa cagttaaatc
     2281 cagcatttct tctcctattt gaacttcatg actactatga ttcattttta gattgccaag
     2341 ggaaatcagc tctgtttcgc ccccacgatg aaggcggcgc aaaatattgt ggacacgcaa
     2401 aaccagttca cgtgggctaa aaggcttagc aataaaatca tctgctccca agctcaggcc
     2461 gtaaatcttg tcctgttcac tggtcttagc agtaataaat aggaaaggct gctctggtga
     2521 taagtattga acctcactga ttaaatcata accatccatc cgaggcatca tgacatctgt
     2581 gataatcaaa tcaatcggtt ttttcttgaa cagctctagc gcttccagtc catcatgggc
     2641 taccaagacc tgataacctg cctgaattaa gtatctctga tgaatatctg tgatttctac
     2701 ctcgtcgtca acgagtaaaa ttgtctttcc catctgtctc tcctttgata aaaacagtgc
     2761 tatactgctt taagtataac actattttta ttgttttacg atgattttaa tctgctattg
     2821 aaagaaagtc ctgattgctg attgagttgt taaactaatc ttagtcagcc cactatccat
     2881 catttatttc cttagctgat tagttttctt cttttttgtt tttcaaacct agaccaccga
     2941 gtaaacctgc aagcgcaagc ccaagtaaac caatacttgc cattgatgtt tgagtctcac
     3001 cagtatttgg tagcatagct ttatcctctg acatcatcgt atcagacatc ttgttagcag
     3061 aagcagccat gttttcacct gccatcgtgt tggtagaact tgtcatggtg tcagcaggca
     3121 tgctatctgt agtacctgta gcatgattgt gattcatcgg agtcacgcca gaaccagagt
     3181 tagaaggtga taatgaacca tttgctgtgt ctgatgtttc tttaacattt atcttaatag
     3241 tgactttttt agttgctacg atgttgtcca agtctggttt accgtctttg ttaccataga
     3301 cattgactgt agcgctgtaa gtttgagtgc cgtttgctcg gaactggtca atgagcgctt
     3361 gtttttcttt gccagctaca tttccgtcca aggctacttg atagaagtat tgacctttgg
     3421 tcttcacgtt ttcgcctagt ggagataggg ctgggttttt agcgtc
//
LOCUS       DAVBOD010000104         2901 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 640-05
            SAMEA1012484-rid20186543.denovo.105, whole genome shotgun sequence.
ACCESSION   DAVBOD010000104 DAVBOD010000000
VERSION     DAVBOD010000104.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012484
            Sequence Read Archive: ERR059358
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2901)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2901)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979948.1
            Genome Coverage       :: 595x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:03:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,266
            CDSs (total)                      :: 2,219
            Genes (coding)                    :: 2,091
            CDSs (with protein)               :: 2,091
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 71 of 128
            Pseudo Genes (incomplete)         :: 50 of 128
            Pseudo Genes (internal stop)      :: 33 of 128
            Pseudo Genes (multiple problems)  :: 22 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2901
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012484-rid20186543.denovo.105"
                     /strain="NIG 640-05"
                     /db_xref="taxon:1313"
     gene            complement(64..1005)
                     /locus_tag="VQ862_002109"
     CDS             complement(64..1005)
                     /locus_tag="VQ862_002109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000806289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HET3116384.1"
                     /translation="MKQTKRIKRWRYYLRRFAYQIKILRVLQSISREKYDEKISASLV
                     YGFLSAVAVNFFFQPGHVYSSGATGLAQIISALSNHWFGFHIPISLSFYAINFPLMVL
                     AWYQIGHKFTVFTFITVSMSSFFIQFVPVATLTEDPIINALFGGVVMGLGIGFALRNN
                     ISSGGTDIVSLTIRKKTGKNVGSISFLVNGTIMLIAGLTFGWKYALYSMITIFVSSRV
                     TDAVFTKQKRMQAMIVTNHPEKVIEKIHKKLHRGATMIHDAEGTYNHERKAVLITVIT
                     RAEFNEFKQIMTQVDPSSFVSVSENVHILGRFVEIDN"
     gene            complement(983..2746)
                     /gene="aspS"
                     /locus_tag="VQ862_002110"
     CDS             complement(983..2746)
                     /gene="aspS"
                     /locus_tag="VQ862_002110"
                     /EC_number="6.1.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000830881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--tRNA ligase"
                     /protein_id="HET3116385.1"
                     /translation="MKRSMYAGRVREEHIGQEITLKGWVGRRRDLGGLIFIDLRDREG
                     IMQLVINPEKVSAEVMATAESLRSEFVIEVTGQVAAREQANDKLPTGAVELNVTALIV
                     LNTAKTTPFEIKDGIEANDDTRLRYRYLDLRRPEMLENLKLRAKVTHSIRNYLDELEF
                     IDVETPFLSKSTPEGARDYLVPSRVNKGHFYALPQSPQITKQLLMNAGFDRYYQIVKC
                     FRDEDLRGDRQPEFTQVDLETSFLTEKEIQDITEGLIARVMKETKGIEVTLPFPRMKY
                     DDAMALYGSDKPDTRFDMLLQDLTEVVKGVDFKVFSEAPAVKAIVVKGAADNYSRKDI
                     DKMTEVAKQYGAKGLAWVKVVDGELNGPVAKFLTGIQEELTTALALEDKDLVLFVADT
                     LEVVNATLGALRGRIAKELGLIDNDKFNFLWVVDWPMFEWSEEEGRYMSAHHPFTLPQ
                     EGTAHELEGDLAKVRAIAYDIVLNGYELGGGSLRINQKDLQERMFKALGFSTEEANDQ
                     FGFLLEAMDYGFPPHGGLAIGLDRFVMLLAGEENIREVIAFPKNNKATDPMTQAPSTV
                     ALKQLEELSLQVEEDETNKTN"
BASE COUNT          847 a          686 c          575 g          793 t
ORIGIN      
        1 aaccatatat acggtaaggc gacgctgacg tggtttgaag agattttcga agagtattaa
       61 tcactaatta tctatctcaa caaatcttcc tagaatatga acattttccg agacagagac
      121 aaaggagctt ggatccactt gtgtcataat ctgtttaaat tcattaaact ctgcacgtgt
      181 aatgacagtg attaaaactg cctttctctc gtgattatag gttccttctg catcatggat
      241 catggttgct ccgcggtgca attttttatg gattttttca attaccttct ctggatgatt
      301 tgtcacaatc atggcctgca tacgcttttg cttagtaaag actgcgtctg tcacacgact
      361 agagacaaag atggtaatca tagaataaag agcgtatttc caaccaaagg tcaaacctgc
      421 tatcagcatg atagttccat ttaccaagaa agaaatacta ccgacattct tacccgtttt
      481 cttgcgaata gtcaggctga cgatatccgt cccaccactg gagatattgt ttcgaagagc
      541 aaaaccaatc cccaaaccca taacaacacc cccaaaaagg gcattgataa tgggatcctc
      601 cgtcaaggtt gccacaggga caaactggat aaagaaggaa ctcatagata ccgtgataaa
      661 ggtaaagacg gtgaacttat ggccaatctg ataccaagct aagaccatca aagggaagtt
      721 aatggcgtaa aagcttagcg aaatcggaat atgaaaacca aaccagtgat tactcaaggc
      781 agagataatc tgtgccagac ctgttgcacc actcgaatac acatgccctg gttggaaaaa
      841 gaaattaact gctactgctg ataaaaaacc atagaccaga gaggccgaaa tcttctcatc
      901 atacttttct cgagagatac tttgtaagac acgtaaaatt tttatctgat aagcaaagcg
      961 gcgcagataa tagcgccacc gcttaattcg ttttgtttgt ttcatcttct tctacttgta
     1021 agctgagttc ctctagttgt ttgagagcga ctgttgatgg agcttgtgtc attgggtcag
     1081 ttgccttgtt gttcttagga aaggcaatga cttcacggat attttcttct ccagcaagca
     1141 acatgacaaa acggtcaagc ccgatagcca aaccaccgtg tggtgggaaa ccatagtcca
     1201 tggcttcaag aaggaaacca aactggtcat tggcttcttc agttgagaaa ccaagagcct
     1261 tgaacatgcg ttcttgaagg tctttttggt tgatacgaag gctaccacca ccaagctcat
     1321 aaccgttcaa gacgatatcg taagcaatgg cacgaacctt agccaaatca ccttctaatt
     1381 cgtgagcagt cccttcctgt ggaagtgtga atggatggtg ggcgctcatg tagcggcctt
     1441 cttcttcaga ccattcaaac atcggccagt caaccaccca aaggaagttg aacttatcat
     1501 tatcaatcaa gccaagctct ttagcaatac gtccacgaag ggcacccagt gttgcattaa
     1561 ccacttcaag cgtatccgcc acaaagagaa ccaagtcctt atcttcaaga gcaagcgctg
     1621 ttgtcaattc ttcttggata ccagtcaaga acttggcaac tggtccgttt aattctccat
     1681 caaccacctt gacccaagca agacctttgg caccatactg tttggctact tccgtcatct
     1741 tgtcgatgtc tttacgtgaa tagttgtccg cagctccttt gaccacaatc gcttttacag
     1801 caggtgcttc tgaaaagact ttaaagtcta cacctttgac cacttctgtc aagtcctgaa
     1861 gcaacatgtc aaaacgagta tctggcttgt cagaaccata aagagccata gcatcatcgt
     1921 atttcatacg agggaacggt agcgttactt cgatgccttt tgtttccttc atcacgcgcg
     1981 cgatcaagcc ttctgtaata tcttggattt ctttctcagt aaggaaggac gtttccaagt
     2041 cgacctgagt aaattcaggc tggcggtctc cacgcaagtc ctcgtcacgg aaacatttaa
     2101 cgatttggta gtaacggtca aaaccagcat tcatcaagag ctgtttcgtg atttgtggac
     2161 tttgaggaag agcgtaaaaa tgccccttat taacacgaga cggcactaaa taatcacgcg
     2221 ccccttcagg cgttgactta gaaaggaatg gtgtctccac gtcgataaac tccaactcat
     2281 ccaaatagtt gcggatagag tgggtcacct tggcacgaag tttaagattt tccaacattt
     2341 ctggacgacg aaggtcaagg taacggtaac gcaaacgtgt atcgtcattt gcctcaatgc
     2401 catccttaat ctcaaatggt gttgtcttag ctgtgttaag cacaataaga gctgtcacgt
     2461 ttaactcaac cgcaccagtt ggcaacttat cattggcttg ctcacgcgca gcgacctgac
     2521 cagtcacctc aataacaaat tcgctacgaa ggctttcagc tgttgccata acctctgcag
     2581 atactttttc agggttgata accaactgca tgattccttc acggtcacga agatcgataa
     2641 agatcaaacc accaaggtca cgacgacggc caacccatcc tttcaaggtt atttcttgtc
     2701 cgatgtgttc ctcacgaaca cgaccagcat acatactacg tttcattatt tctctcctct
     2761 tttattctgt tactatttta ccataaaagc gcaggctctt catgaaaatc atcagaaaag
     2821 tttgccagtc tttaaaagtc aggtgaaagc cctaaaaatt agcgctaatg ctcttcgaaa
     2881 atctcttcaa accacgtcag c
//
LOCUS       DAVBOD010000105         2777 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 640-05
            SAMEA1012484-rid20186543.denovo.106, whole genome shotgun sequence.
ACCESSION   DAVBOD010000105 DAVBOD010000000
VERSION     DAVBOD010000105.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012484
            Sequence Read Archive: ERR059358
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2777)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2777)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979948.1
            Genome Coverage       :: 595x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:03:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,266
            CDSs (total)                      :: 2,219
            Genes (coding)                    :: 2,091
            CDSs (with protein)               :: 2,091
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 71 of 128
            Pseudo Genes (incomplete)         :: 50 of 128
            Pseudo Genes (internal stop)      :: 33 of 128
            Pseudo Genes (multiple problems)  :: 22 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2777
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012484-rid20186543.denovo.106"
                     /strain="NIG 640-05"
                     /db_xref="taxon:1313"
     gene            <1..174
                     /locus_tag="VQ862_002111"
     CDS             <1..174
                     /locus_tag="VQ862_002111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000462832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3116386.1"
                     /translation="QVRNHAYERGREDKWQEIRKNIRREFKGFTYDNEPPVGLRPEPL
                     ALPEPKQSAIRFL"
     gene            190..486
                     /locus_tag="VQ862_002112"
     CDS             190..486
                     /locus_tag="VQ862_002112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3116387.1"
                     /translation="MQELIESLDNLIMIVKELEGRESTSRHFITIWENDYKNLLRVKE
                     YLTDYEKLAKDYRYMTLKNKLLKIEKMELEGRYIYEDMRMKYRANRRKWGARYV"
     gene            479..1306
                     /locus_tag="VQ862_002113"
     CDS             479..1306
                     /locus_tag="VQ862_002113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001289767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage replisome organizer N-terminal
                     domain-containing protein"
                     /protein_id="HET3116388.1"
                     /translation="MSEIKWIKIKTDIFDDEKMCLIDASPDRDAIIVIWIKLITLAGK
                     LNTKGVLTISKNIVYTDEMLAQTFHRPLNTVRMALEVFEKFGMVEKIDGVIMLPNWEK
                     HQNIDGMEKIKEQNRNRAARHRQKQKLLAQNNESNVTDNVMDNVTVTHGNALDKELDK
                     DIEINNNKVMISSSLSENLKNSGIHLTDKSHQQLLDYVGLDGMSFDMLNRAVEKTSGS
                     HKPSFNYLIAILESWKKKGFTSIEQVDEDDRKYKEGKKSRQQNDKTSEQEVRDEWGF"
     gene            1446..2216
                     /locus_tag="VQ862_002114"
     CDS             1446..2216
                     /locus_tag="VQ862_002114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000228202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HET3116389.1"
                     /translation="MVDNVFEEIALSYRRNTEQQEEFCEKHNIPLIKILRTESVVCRM
                     CESERIHEENQERVNELANAENERERKYYLEKFSLYDEILKNATLDNFETPTEKEAEK
                     LAFAKRICREWSEGARNNIVLQGEAGTGKSHLAFAMVKALSEYTKEIAIFINVTDLLM
                     KIKADFSQEEFLVNKIASAKFLVLDDLGMEKDSEWSFTILYNILNKRSNTIITTNLIS
                     ADIQKRYGRPFMSRLMKGVDKDHLMVFNDLTNKRKQYF"
     gene            2231..2425
                     /locus_tag="VQ862_002115"
     CDS             2231..2425
                     /locus_tag="VQ862_002115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000470305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3116390.1"
                     /translation="MFILKHGTREDKPFLRSAIISVTGLDISCSEEKKAMRFISRAAA
                     LQVSKALRGSFGNFYPVEVE"
     gene            2425..2652
                     /locus_tag="VQ862_002116"
     CDS             2425..2652
                     /locus_tag="VQ862_002116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000891963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3116391.1"
                     /translation="MLELYFVYNGHCKFFLGRFDNVDDLIEQMEDHQWAFSAITHPRF
                     QKHIGQRTTRFDYGSKDCYYLATFSGGEKND"
BASE COUNT          945 a          427 c          654 g          751 t
ORIGIN      
        1 caagtgcgta atcatgcata tgaacgtggt agagaggaca aatggcaaga aattcgcaag
       61 aatattcgca gagagttcaa aggattcaca tatgacaacg aaccgcctgt aggcttgcgt
      121 cctgagccgt tagctttgcc agaacctaaa cagtctgcaa tcagattttt gtaatgagga
      181 ggtcaggaaa tgcaagaatt gattgaatcg ctggataacc tgattatgat tgttaaagaa
      241 ctggaaggaa gggaatcaac ttcaagacat tttattacga tatgggaaaa cgattataaa
      301 aatctattac gagtcaaaga atacctaacc gactatgaaa aactagcaaa ggactatcgt
      361 tatatgaccc ttaaaaataa gctgctaaag attgaaaaaa tggagctgga aggcaggtac
      421 atctatgaag atatgcggat gaagtatcgt gccaatcgca ggaagtgggg tgctcggtat
      481 gtctgaaatc aagtggataa aaatcaaaac ggatattttt gacgatgaaa agatgtgtct
      541 aattgatgcc tcgcctgatc gtgatgcaat tattgtaatc tggatcaaac ttataacact
      601 agcaggcaaa ttgaatacaa aaggcgtact aaccatttct aaaaacattg tatacaccga
      661 tgaaatgctt gcacaaacgt tccaccgtcc gttgaataca gttcgtatgg ctcttgaagt
      721 ttttgaaaag tttggaatgg ttgaaaaaat cgatggagtg ataatgttac ccaattggga
      781 gaaacatcag aacattgacg gcatggaaaa aataaaagag caaaatcgaa atagagcagc
      841 acgtcaccga caaaaacaga aattacttgc acagaacaac gaaagtaacg ttactgataa
      901 cgttatggat aacgttacag taacgcatgg taacgcacta gataaagaat tagataaaga
      961 tatagagata aataataata aggtgatgat tagttccagc ctttctgaaa atttgaaaaa
     1021 tagcggaatc catctaactg ataagtcaca tcaacagtta cttgattatg tgggacttga
     1081 tggaatgagt ttcgatatgt tgaaccgtgc agtcgagaaa acttccggat cacacaaacc
     1141 tagtttcaat tacctaatag ccattcttga aagttggaaa aagaaaggct tcacatcgat
     1201 tgagcaggtg gatgaggacg accgtaaata taaagagggt aagaagtcaa gacaacaaaa
     1261 cgataaaaca tcggaacagg aggtaaggga cgaatgggga ttttagaact aattgagcag
     1321 ttcgagattg actattatcc gttaagctac gagaagaaaa ctcttttagc agaccaacca
     1381 attcatccag tggttgcctg cttgtctgaa atggctagct ggcatgaatg cggaggtcgg
     1441 ctagtatggt agacaatgtg tttgaggaaa tcgccttatc ttatcgtagg aatacagaac
     1501 aacaagaaga gttctgcgaa aagcataaca tccctttgat aaagatattg aggaccgaga
     1561 gtgttgtatg tcgcatgtgt gaatctgagc ggattcatga agaaaatcag gaaagagtga
     1621 atgaactggc taatgctgag aatgagcgag agaggaaata ctatcttgaa aagttctctc
     1681 tttatgatga aattttgaaa aatgctactt tggacaattt tgaaacacca accgaaaaag
     1741 aagcggaaaa gctagctttt gcaaagagga tttgtcgtga gtggtctgag ggtgctagga
     1801 acaacattgt acttcaggga gaagctggaa ctggtaagag tcatttggct tttgctatgg
     1861 ttaaggctct atctgagtac acgaaagaga ttgctatttt tattaacgta actgacttgc
     1921 tgatgaagat taaagctgat tttagtcagg aagagtttct ggtcaataaa attgctagtg
     1981 ctaagttctt ggttttggat gatttaggaa tggaaaaaga tagcgaatgg tcatttacta
     2041 ttctctacaa tatcttgaat aagcgttcaa acacaatcat taccacaaat ttgatttctg
     2101 ccgatattca aaaaagatat ggcagacctt tcatgtccag actaatgaag ggtgtagata
     2161 aagaccattt gatggttttc aatgatttga caaacaagcg aaagcaatat ttttagaata
     2221 ggggtggctg atgtttattt taaagcatgg gacaagagag gataagccgt ttctaaggtc
     2281 tgcaattatc agtgtgactg gcttggatat ttcgtgttct gaggagaaga aagccatgcg
     2341 gtttatttct cgggcggcag ccttacaggt tagcaaggca ttgagaggtt cctttgggaa
     2401 cttctaccct gtcgaggtgg agtgatgtta gagctttatt tcgtctacaa cgggcactgt
     2461 aagtttttcc ttgggaggtt tgacaatgtc gatgatctca ttgagcagat ggaagaccat
     2521 cagtgggctt tctcagctat cactcatcca aggtttcaga agcacattgg tcagcggacg
     2581 acacgatttg actacggttc taaggattgt tactatttag cgactttttc aggaggagaa
     2641 aaaaatgatt gaacttatta aagaatttgg aatggctatt ctgtggttat ttcttggcta
     2701 tttagtcggg gaacgtgcag caagaaagga aaagaaagat gatcaataac gttacatttt
     2761 tagtgggagg taagaaa
//
LOCUS       DAVBOD010000106         2633 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 640-05
            SAMEA1012484-rid20186543.denovo.107, whole genome shotgun sequence.
ACCESSION   DAVBOD010000106 DAVBOD010000000
VERSION     DAVBOD010000106.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012484
            Sequence Read Archive: ERR059358
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2633)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2633)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979948.1
            Genome Coverage       :: 595x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:03:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,266
            CDSs (total)                      :: 2,219
            Genes (coding)                    :: 2,091
            CDSs (with protein)               :: 2,091
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 71 of 128
            Pseudo Genes (incomplete)         :: 50 of 128
            Pseudo Genes (internal stop)      :: 33 of 128
            Pseudo Genes (multiple problems)  :: 22 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2633
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012484-rid20186543.denovo.107"
                     /strain="NIG 640-05"
                     /db_xref="taxon:1313"
     gene            423..2528
                     /locus_tag="VQ862_002117"
     CDS             423..2528
                     /locus_tag="VQ862_002117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001063457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HET3116392.1"
                     /translation="MNNNFNNFNNMDDLFNQLMGGMRGYSSENRRYLINGREVTSEEF
                     AHYRATGQLPGNAETDVQMPQQASGMKQDGVLAKLGRNLTAEAREGKLDPVIGRNKEI
                     QETSEILSRRTKNNPVLVGDAGVGKTAVVEGLAQAIVNGDVPAAIKNKEIISIDISGL
                     EAGTQYRGSFEENVQNLVNEVKEAGNIILFFDEIHQILGAGSTGGDSGSKGLADILKP
                     ALSRGELTVIGATTQDEYRNTILKNAALARRFNEVKVNAPSAENTFKILQGIRDLYQQ
                     HHNVILPDEVLKAAVDYSVQYIPQRSLPDKAIDLVDVTAAHLAAQHPVTDVHAVEREI
                     ETEKDKQEKAVEAEDFEAALNYKTRIAELERKIENHTEDMKVTASVNDVAESVERMTG
                     IPVSQMGASDIERLKDMAHRLQDKVIGQDKAVEAVARAIRRNRAGFDEGNRPIGSFLF
                     VGSTGVGKTELAKQLALDMFGTQDAIIRLDMSEYSDRTAVSKLIGTTAGYVGYDDNSN
                     TLTERVRRNPYSIILLDEIEKADPQVITLLLQVLDDGRLTDGQGNTVNFKNTVIIATS
                     NAGFGYEANLTEDADKPELMDRLKPFFRPEFLNRFNAVIEFSHLTKEDLSKIVDLMLA
                     EVNQTLAKKDIDLVVSQAAKDYITEEGYDEVMGVRPLRRVVEQEIRDKVTDFHLDHLD
                     AKHLEADMEDGVLVIREKA"
BASE COUNT          847 a          474 c          610 g          702 t
ORIGIN      
        1 tttcatttta atatatagtt ttgagatggt tgatagaact gacgaagtca gctcaaaaca
       61 tggttttgag gttgtagata aggagaagct gatgtggttt gaagaggttt tcgaagagtg
      121 taaaaaaata ttggtcagtt aaagccaaaa ctcttgacct tttctgacca atgtagtata
      181 ttatgaacgt aaggtaaatg aaagccttac tagaacactt atttaaagta aaatagaaag
      241 aggtgggtct atgtttcatc tagaaatctt cagaagtaaa gatggtctac tcctgcttga
      301 aaaagaaaaa ccagaaatag tacgtagggt agcggtttaa ctagtctaaa ttttttaaaa
      361 caatggtcaa agatagtcaa tatcagtaat cataactaag taaacaaaaa gaggtaaaga
      421 atatgaataa caactttaat aattttaata acatggatga tttatttaac caattgatgg
      481 gtggtatgcg aggatatagt tctgaaaatc gccgttactt aattaatgga cgcgaagtca
      541 catctgagga atttgctcac tatcgtgcga ctggtcaatt accaggaaat gcagaaactg
      601 atgtgcaaat gccacaacag gcatcaggta tgaaacaaga cggtgtcctt gcaaaactag
      661 gtcgaaactt gacagcagaa gcgcgtgagg gtaagttgga tcctgttatc ggacgaaaca
      721 aggaaattca agaaacatct gaaatcctct cacgccgcac caagaacaat cctgttttgg
      781 tcggagatgc aggtgttggt aagacagcag ttgtcgaagg tctagcgcaa gccattgtga
      841 acggagatgt tcctgctgct atcaagaaca aggaaattat ttctattgat atctcaggtc
      901 ttgaggctgg tactcaatac cgtggtagct ttgaagaaaa tgtccaaaac ttagtcaatg
      961 aagtgaaaga agcagggaat attatcctct tctttgatga aattcaccaa attcttggtg
     1021 ctggtagcac tggtggagac agtggttcta aaggacttgc ggatattctc aagccagctc
     1081 tctctcgtgg agaattgaca gtgattgggg caacaactca agacgaatac cgtaacacca
     1141 tcttgaagaa tgctgctctt gctcgtcgtt tcaacgaagt gaaggtcaat gctccttcag
     1201 cagagaatac ttttaaaatt cttcaaggca ttcgtgacct ctatcaacaa catcacaatg
     1261 tcatcttgcc agacgaagtc ttgaaagcag cggtggatta ttctgttcaa tacattcctc
     1321 aacgtagctt gccagataag gctattgacc ttgtcgatgt aacagctgct cacttggcgg
     1381 ctcaacatcc agtaacagat gtgcatgctg ttgaacgaga aatcgaaacg gaaaaagaca
     1441 agcaagaaaa agcagttgaa gcagaagatt ttgaagcagc tctaaactat aaaacgcgca
     1501 ttgcagaatt ggaaaggaaa atcgaaaacc acacagaaga tatgaaagtg actgcaagtg
     1561 tcaacgatgt ggctgaatct gtggaacgaa tgacaggtat cccagtatcg caaatgggag
     1621 cttcagatat cgaacgtttg aaagatatgg ctcatcgctt gcaagacaag gtgattggtc
     1681 aagataaggc cgtagaagct gtagctcgtg ctatccgtcg taaccgtgct ggttttgatg
     1741 aaggaaatcg cccaatcggc agcttcctct ttgtagggtc tactggggtt ggtaagacgg
     1801 agcttgctaa gcaattggca ctcgatatgt ttggaaccca ggatgcgatt atccgtttgg
     1861 atatgtctga atacagtgac cgcacagctg tttctaagct aattggtaca acagcaggct
     1921 atgtgggtta tgatgacaat agcaatacct taacagaacg tgttcgtcgc aatccatact
     1981 ctatcattct cttggatgaa attgaaaagg ctgaccctca agttattacc cttctcctcc
     2041 aagttctaga tgatggtcgt ttgacagatg gtcaaggaaa tacagtaaac ttcaagaaca
     2101 ctgtcattat tgcgacctca aatgctggat ttggctatga agccaacttg acagaagatg
     2161 cggataaacc agaattgatg gaccgtttga aacccttctt ccgtccagaa ttcctcaacc
     2221 gctttaatgc agtcatcgag ttctcacact tgactaagga agacctttct aagattgtag
     2281 atttgatgtt ggctgaagtt aaccaaacct tggctaagaa agacattgac ttggtagtca
     2341 gtcaagcggc taaagattat atcacagaag aaggttacga cgaagtcatg ggggttcgtc
     2401 ctctccgtcg agtggttgaa caagaaattc gtgataaggt gacagacttc cacttggatc
     2461 atttagatgc taaacatctg gaagcagata tggaagatgg cgttttggtt attcgtgaga
     2521 aagcctaaga cagaattttg aggataaaaa agaaggagcc agctgaaaaa aactggttcc
     2581 tttctaggta cgacgggcat gtcgtgtagt aggttgaaac tagaatagta cac
//
LOCUS       DAVBOD010000107         2481 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 640-05
            SAMEA1012484-rid20186543.denovo.108, whole genome shotgun sequence.
ACCESSION   DAVBOD010000107 DAVBOD010000000
VERSION     DAVBOD010000107.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012484
            Sequence Read Archive: ERR059358
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2481)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2481)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979948.1
            Genome Coverage       :: 595x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:03:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,266
            CDSs (total)                      :: 2,219
            Genes (coding)                    :: 2,091
            CDSs (with protein)               :: 2,091
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 71 of 128
            Pseudo Genes (incomplete)         :: 50 of 128
            Pseudo Genes (internal stop)      :: 33 of 128
            Pseudo Genes (multiple problems)  :: 22 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2481
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012484-rid20186543.denovo.108"
                     /strain="NIG 640-05"
                     /db_xref="taxon:1313"
     gene            complement(173..838)
                     /locus_tag="VQ862_002118"
     CDS             complement(173..838)
                     /locus_tag="VQ862_002118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001283913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkA family potassium uptake protein"
                     /protein_id="HET3116393.1"
                     /translation="MSDRTIGILGLGIFGSSVLAALAKQDMNIIAIDDHAERINQFEP
                     VLARGVIGDITDEELLRSAGIDTCDTVVVATGENLESSVLAVMHCKSLGVPTVIAKVK
                     SQTAKKVLEKIGADSVISPEYEMGQSLAQTILFHNSVDVFQLDKNVSIVEMKIPQSWA
                     GQSLSKLDLRGKYNLNILGFREQENSPLDVEFGPDDLLKADTYILAVINNQYLDTLVA
                     LNS"
     gene            complement(852..2231)
                     /locus_tag="VQ862_002119"
     CDS             complement(852..2231)
                     /locus_tag="VQ862_002119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000897732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HET3116394.1"
                     /translation="MLFKLSKEKIELGLSRLSPARRIFLSFALVILLGSLLLSLPFVQ
                     VESSRATYFDHLFTAVSAVCVTGLSTLPVAHTYNIWGQIICLLLIQIGGLGLMTFIGV
                     FYIQSKQKLSLRSRATIQDSFSYGETRSLRKFVYSIFLTTFLVESLGAILLSFRFIPQ
                     LGWGRGLFSSIFLAISAFCNAGFDNLGSTSLFAFQTDLLVNLVIAGLIITGGLGFMVW
                     FDLAGHVGRKKKGRLHFHTKLVLLLTIGLLLFGTATTLFLEWNNAGTIGNLPVADKVL
                     VSFFQTVTMRTAGFSTIDYTQAHPVTLLIYILQMFLGGAPGGTAGGLKITTFFVLLVF
                     ARSELLGLPHANVARRTIAPRTVQKSFSVFIIFLMSFLIGLILLGITAKGNPPFIHLI
                     FETISALSTVGVTANLTPDLGKLALSVIMPLMFMGRIGPLTLFVSLADYHPEKKDMIH
                     YMKADISIG"
BASE COUNT          813 a          565 c          463 g          640 t
ORIGIN      
        1 cccgcagcta gtttcctagt ttgatctttg attttcattg agtattactc tctcttgtca
       61 cttccttcta ttttaccata aagtccagcc tttgaagaac ttttactaga agacaagggg
      121 cttctgtctc tatttgccat cttgggcatc aaaaaagagg ggtcatccct ctttacgaat
      181 tcaatgctac tagggtatcc aaatactggt tgttgatgac tgccaaaata taggtatctg
      241 ctttcaagag gtcatctggt ccaaattcaa catccaatgg ggaattttcc tgctctcgga
      301 aacccaaaat attcagattg tatttgccac ggaggtctaa tttactcaga ctttgacctg
      361 cccaagactg aggaattttc atctccacga tagacacatt tttatccaac tgaaagacat
      421 caacactatt atggaaaaga atggtctgtg ctagagactg ccccatttca tactctggcg
      481 agataaccga gtcagctcca atcttttcta gcactttctt agcggtctga cttttgacct
      541 tagcaataac agtcggtacc cccaaactct tacagtgcat aaccgcaagc acactcgact
      601 ccagattttc acctgtcgcg actacaacgg tatcgcaggt atcaatccct gctgatctca
      661 ataattcttc atctgtgatg tcaccaatca ctccacgcgc caaaactggc tcaaactgat
      721 tgatgcgctc tgcgtggtca tcaatagcga taatattcat atcctgcttg gctagggcag
      781 ctaggacact gctcccaaaa attcccaagc ccaaaattcc aatcgtacga tctgacatgc
      841 tctttccttt cttaaccaat actaatatct gctttcatat agtgaatcat atctttcttt
      901 tctggatggt aatctgccaa gctaacaaac aaggtcaagg gaccaattcg tcccataaac
      961 ataagtggca tgataacact gagagccaat ttcccaaggt caggagtcag atttgccgtt
     1021 acaccaactg tactaagagc tgaaatggtt tcaaatatga ggtggataaa gggaggattg
     1081 cctttggctg ttatccctag cagaatcaat cctatcaaga agctcatcaa aaagataata
     1141 aagacactaa aggatttttg aaccgttcgc ggcgcaatcg ttcgtctcgc aacattggca
     1201 tgaggcaagc ctagaagctc acttcgtgca aagaccaaga ggacaaaaaa tgtcgtaatc
     1261 ttgagtcccc cagctgttcc tccaggtgcc ccacctagaa acatctgtaa gatataaatc
     1321 aaaagagtca caggatgagc ctgagtataa tctatcgtag aaaagccagc tgttcgcatc
     1381 gtcactgttt gaaaaaagct aactaaaacc ttatcggcaa cagggagatt gccaatcgtt
     1441 ccagcattgt tccactcaag aaagagagta gttgccgttc caaataacaa caaacctata
     1501 gtcaacaata gtacaagctt cgtatgaaag tgcagacgtc cttttttctt tcttcctaca
     1561 tgaccagcca aatcaaacca gaccataaaa ccaaggccgc ctgtaataat caagcctgca
     1621 ataaccagat tgaccagtaa atcggtctga aaagcaaata aactggtgct ccctaaatta
     1681 tcaaaaccgg cattacagaa ggctgagatc gctagaaaaa tggaactaaa aagaccacgt
     1741 ccccagccaa gttgaggaat aaagcgaaaa ctaagcaaaa tagctcccaa gctctcaacc
     1801 aaaaaggtcg tgagaaaaat agaatagaca aactttctca aagatcgagt ttctccataa
     1861 ctaaaactat cctgaatagt tgcacggcta cgaagactaa gcttttgctt gctctggata
     1921 tagaaaaccc caataaaggt catgagccct agaccaccga tctgaatcaa gagcaaacag
     1981 attatttggc cccagatatt ataggtgtga gctactggaa gggttgagag acctgtcaca
     2041 cagactgcag agacagcagt gaaaagatga tcaaaataag tcgctcgtga gctttcaact
     2101 tggacaaagg gcaagctcaa aagaagagag cctagtaaaa tgaccaaggc aaaactcaaa
     2161 aaaatacgac gggctggcga taaacgagat aagcctagct ctattttttc cttagataat
     2221 ttgaataaca tgtttccatt gtaccataaa aagttcgaaa tgacttagat aggataaggc
     2281 aaaatctact aacaccaagc ctaaaaaatg ccaccttttt attgatagct taggcaagaa
     2341 caatacttga tagatgtgac tataggtcaa aaaagcaaga caggagcttt taacgccagc
     2401 tactctatat gcttttcagg agaaaatttc tctttttgat tataggcaat gagaaccaag
     2461 gcatcgctta gaaagctagt c
//
LOCUS       DAVBOD010000108         2419 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 640-05
            SAMEA1012484-rid20186543.denovo.109, whole genome shotgun sequence.
ACCESSION   DAVBOD010000108 DAVBOD010000000
VERSION     DAVBOD010000108.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012484
            Sequence Read Archive: ERR059358
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2419)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2419)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979948.1
            Genome Coverage       :: 595x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:03:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,266
            CDSs (total)                      :: 2,219
            Genes (coding)                    :: 2,091
            CDSs (with protein)               :: 2,091
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 71 of 128
            Pseudo Genes (incomplete)         :: 50 of 128
            Pseudo Genes (internal stop)      :: 33 of 128
            Pseudo Genes (multiple problems)  :: 22 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2419
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012484-rid20186543.denovo.109"
                     /strain="NIG 640-05"
                     /db_xref="taxon:1313"
     gene            57..344
                     /locus_tag="VQ862_002120"
     CDS             57..344
                     /locus_tag="VQ862_002120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000194859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3116395.1"
                     /translation="MTQTLEEGMKNQSKCIKIPMEIRPFDVGYRIVNKHGQALALKNG
                     ASIFALPSLAEKAIKKEFGKNDPDFDIEKHFVEEVAIVNLSKFHSYFEGVE"
     gene            344..532
                     /locus_tag="VQ862_002121"
     CDS             344..532
                     /locus_tag="VQ862_002121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001277861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="topoisomerase"
                     /protein_id="HET3116396.1"
                     /translation="MSCSENLKKEKELTAAISNFKIEVLQNDDKLSSLSLSNIKRQAR
                     DLYECLVWLQYNAEESGR"
     gene            529..867
                     /locus_tag="VQ862_002122"
     CDS             529..867
                     /locus_tag="VQ862_002122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000119454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3116397.1"
                     /translation="MSYDLEILVKIESGDYICIAEPKYSSPTYNLGRMFRVAMNWDFD
                     QDTTYNIADVLDNIQRGISELERYPEKYVQYEPENRWGTVSVALEVLKSLKECILEQD
                     IDTKYLYMRW"
     gene            869..1129
                     /locus_tag="VQ862_002123"
     CDS             869..1129
                     /locus_tag="VQ862_002123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000819325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1372 family protein"
                     /protein_id="HET3116398.1"
                     /translation="MRRFIAIWILVSAGLNIWHMDRIRDLEEKKPMVVYKADNAGAEI
                     FGRVVEKGRHGKLYTVTIRDYGIFVVTKEQFEKIRVGDEVLL"
     gene            1129..1587
                     /locus_tag="VQ862_002124"
     CDS             1129..1587
                     /locus_tag="VQ862_002124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000340952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3116399.1"
                     /translation="MDDILQALAKMLNMTVDEVSSLLTTFKGNAPQIYEMFVKEKMFY
                     DLFSLFQIMSIVIFSISAVVLAVLTLIYFTYDGGFVYSYDIRTGKTEEEIKLERIERK
                     RKDLKIPLKISCISSSASLITLVIAIVLKATLAPNYIFIVNEILPKLTKR"
     gene            1701..1979
                     /locus_tag="VQ862_002125"
     CDS             1701..1979
                     /locus_tag="VQ862_002125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3116400.1"
                     /translation="MKRLGIIIGAVFVIVVSPFVVQYGWNEIITTIVPVGKITVWQAL
                     GMDALLSFIWPVLSSKKESEEDYSYAVKSSISKIITCAFLIWLASLFI"
     gene            1991..>2419
                     /locus_tag="VQ862_002126"
     CDS             1991..>2419
                     /locus_tag="VQ862_002126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000612384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3116401.1"
                     /translation="MIPKFRGLSIDEKSKGEWQYGHLIEDRGRAFIINEVVEANEQYI
                     TIGSWCPVNPATLGQSTGLRDKNGKEIFEGDIVRTTRFLGRADEIGGFYEYDKEFIGI
                     VKQLEGSWVIDTGSDAVCLWTEIEENEIIGNIYENKEFGGR"
BASE COUNT          836 a          311 c          558 g          714 t
ORIGIN      
        1 gcaaacttcg gctgggtgtt tgattgtgaa ggaattgaga ttgaggaggt ggagtgatga
       61 cacaaacact tgaagaagga atgaagaatc aaagtaaatg cataaaaatc ccaatggaaa
      121 tcagaccgtt tgatgtgggt tatcgaatag taaataaaca cggtcaagcg cttgccttaa
      181 aaaacggagc aagtatattc gctttacctt cgctggccga aaaagcgata aagaaagagt
      241 ttggaaaaaa tgatccagac tttgacattg aaaaacattt tgttgaagag gtcgctattg
      301 tcaatttaag taaatttcat agttactttg agggggtgga gtgatgtcat gtagtgaaaa
      361 tttaaaaaaa gaaaaagaat tgactgctgc tatttcaaat ttcaagatag aagtcttaca
      421 aaatgatgat aaattgagca gtctatcatt aagcaacatc aaaaggcaag caagggatct
      481 atatgaatgc ttagtatggt tgcagtataa tgcggaggaa tcaggtagat gagttatgat
      541 ttggaaatat tagtaaaaat agagagtgga gattatattt gtatcgctga acctaaatat
      601 agttctccga cctacaatct tggaagaatg tttagagttg ctatgaactg ggattttgat
      661 caagacacta cgtacaacat cgctgatgtt ttagataaca ttcaacgcgg tatctctgaa
      721 ctagaacggt accctgaaaa gtatgtgcag tatgaacctg aaaatagatg gggaacagtt
      781 agcgttgcat tggaggtttt aaagtcactg aaagagtgta ttttagaaca agatattgat
      841 acgaaatatt tatatatgag gtggtaatat gagacgattc atagctatct ggattcttgt
      901 ctctgccgga ttgaacatct ggcatatgga caggattcga gatttggaag agaaaaagcc
      961 gatggttgtc tataaagctg ataacgctgg cgctgagata ttcgggcgtg tcgttgaaaa
     1021 aggacggcat gggaagttgt atacagtaac tatcagagac tatgggattt tcgtagttac
     1081 gaaagagcag tttgagaaaa tcagagtagg ggatgaggtg ttactctaat ggatgatatt
     1141 ttacaagctt tagcaaaaat gctaaatatg actgttgatg aagtaagttc tttgcttaca
     1201 acatttaaag ggaatgcacc acagatttat gaaatgttcg ttaaagaaaa gatgttttat
     1261 gatctcttca gtctttttca aatcatgtca attgtaatat ttagtatttc tgcagtagtt
     1321 ttagcagttt taactctcat atattttaca tacgatggtg gttttgttta ttcctatgat
     1381 atacgtacag gaaaaaccga ggaagaaatt aaattagaac gcattgaacg gaaaagaaag
     1441 gacttaaaaa taccactaaa aattagttgc atttcatcaa gcgcaagttt gataacatta
     1501 gttattgcaa ttgttttaaa agcaactctt gcacctaatt atatattcat cgtgaatgag
     1561 attttaccaa aattaacgaa gagataggag ttatcatgaa cacaatagag aaagtcaaac
     1621 aatggtttat tgaccgtgat ttagaaaacg gtagggtcgt tggattgatg gtgctttcgt
     1681 caaagaggag gatttataaa atgaaaagac taggaatcat tattggggcg gtatttgtaa
     1741 tcgttgtatc gccatttgta gttcagtatg gatggaatga gattatcaca acaattgttc
     1801 cagttggtaa aattacagtc tggcaagcat tagggatgga tgcactacta tctttcatct
     1861 ggcctgtgtt atctagcaaa aaagaatctg aagaggatta ttcgtatgcg gtaaaaagca
     1921 gtatttcaaa aatcattaca tgtgcatttt tgatatggtt agctagtttg tttatttaag
     1981 gagtgttagc atgataccaa aatttagagg gttatccatt gacgaaaaaa gcaaaggaga
     2041 atggcaatac ggacatttaa ttgaagatag aggaagagca tttattatca acgaagtggt
     2101 agaagccaat gaacaataca ttactatagg ttcttggtgt cctgtaaatc cagcaacatt
     2161 aggacaatca acaggtctca gagacaagaa cggcaaggaa atctttgaag gcgatattgt
     2221 acgaactact agatttttgg gtagagctga cgaaattggc ggtttctatg agtatgacaa
     2281 ggaatttata gggattgtta agcagcttga gggttcttgg gtaattgata cgggcagtga
     2341 cgcagtatgt ttatggactg aaattgaaga aaatgaaatc atcggcaaca tctatgaaaa
     2401 taaggagttt ggaggacgc
//
LOCUS       DAVBOD010000109         2364 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 640-05
            SAMEA1012484-rid20186543.denovo.110, whole genome shotgun sequence.
ACCESSION   DAVBOD010000109 DAVBOD010000000
VERSION     DAVBOD010000109.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012484
            Sequence Read Archive: ERR059358
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2364)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2364)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979948.1
            Genome Coverage       :: 595x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:03:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,266
            CDSs (total)                      :: 2,219
            Genes (coding)                    :: 2,091
            CDSs (with protein)               :: 2,091
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 71 of 128
            Pseudo Genes (incomplete)         :: 50 of 128
            Pseudo Genes (internal stop)      :: 33 of 128
            Pseudo Genes (multiple problems)  :: 22 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2364
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012484-rid20186543.denovo.110"
                     /strain="NIG 640-05"
                     /db_xref="taxon:1313"
     gene            <1..1523
                     /gene="phtA"
                     /locus_tag="VQ862_002127"
     CDS             <1..1523
                     /gene="phtA"
                     /locus_tag="VQ862_002127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtA"
                     /protein_id="HET3116402.1"
                     /translation="FDPAQITSRTARGVAVPHGDHYHFIPYSHMSELEERIARIIPLR
                     YRSNHWVPDSRPEQPSPQPTPEPSPGPQPAPNLKIDSNSSLVSQLVRKVGEGYVFEEK
                     GISRYVFAKDLPSETVKNLESKLSKQESVSHTLTAKKENVAPRDQEFYDKAYNLLTEA
                     HKALFENKGRNSDFQALDKLLERLNDESTNKEKLVDDLLAFLAPITHPERLGKPNSQI
                     EYTEDEVRIAQLADKYTTSDGYIFDEHDIISDEGDAYVTPHMGHSHWIGKDSLSDKEK
                     VAAQAYTKEKGILPPSPDADVKANPTGDSAAAIYNRVKGEKRIPLVRLPYMVEHTVEV
                     KNGNLIIPHKDHYHNIKFAWFDDHTYKAPNGYTLEDLFATIKYYVEHPDERPHSNDGW
                     GNASEHVLGKKDHSEDPNKNFKADEEPVEETPAEPEVPQVETEKVEAQLKEAEVLLAK
                     VTDSSLKANATETLAGLRNNLTLQIMDNNSIMAEAEKLLALLKGSNPSSVSKEKIN"
     gene            1681..>2364
                     /locus_tag="VQ862_002128"
     CDS             1681..>2364
                     /locus_tag="VQ862_002128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
                     /protein_id="HET3116403.1"
                     /translation="MKINKKYLAGSVATLVLSVCAYELGLHQAQTVKENNRVSYIDGK
                     QATQKTENLTPDEVSKREGINAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDAIISEE
                     LLMKDPNYQLKDEDIISEIKGGYVIKVDGKYYVYLKDAAHADNVRTKEEINRQKQEHS
                     QHREGGTPRNDGAVALARSQGRYTTDDGYIFNASDIIEDTGDAYIVPHGDHYHYIPKN
                     ELSASELAAA"
BASE COUNT          831 a          431 c          476 g          626 t
ORIGIN      
        1 ttttcgaccc agcgcaaatc acaagtcgaa cagctagagg tgttgcagtg ccacacggag
       61 atcattacca cttcatccct tactctcaca tgtctgaatt ggaagaacga atcgctcgta
      121 ttattcccct tcgttatcgt tcaaaccatt gggtaccaga ttcaaggcca gaacaaccaa
      181 gtccacaacc gactccggaa cctagtccag gcccgcaacc tgcaccaaat cttaaaatag
      241 actcaaattc ttctttggtt agtcagctgg tacgaaaagt tggggaagga tatgtattcg
      301 aagaaaaggg catctctcgt tatgtctttg cgaaagattt accatctgaa actgttaaaa
      361 atcttgaaag taagttatca aaacaagaga gtgtttcaca cactttaact gctaaaaaag
      421 aaaatgttgc tcctcgtgac caagaatttt atgataaagc atataatctg ttaactgagg
      481 ctcataaagc cttgtttgaa aataagggtc gtaattctga tttccaagcc ttagacaaat
      541 tattagaacg cttgaatgat gaatcgacta ataaagaaaa attggtagat gatttattgg
      601 cattcctagc accaattacc catccagagc gacttggcaa gccaaattct caaattgagt
      661 atactgaaga cgaagttcgt attgctcaat tagctgataa gtatacaacg tcagatggtt
      721 acatttttga tgaacatgat ataatcagtg atgaaggaga tgcatatgta acgcctcata
      781 tgggccatag tcactggatt ggaaaagata gcctttctga taaggaaaaa gttgcagctc
      841 aagcctatac taaagaaaaa ggtatcctac ctccatctcc agacgcagat gttaaagcaa
      901 atccaactgg agatagtgca gcagctattt acaatcgtgt gaaaggggaa aaacgaattc
      961 cactcgttcg acttccatat atggttgagc atacagttga ggttaaaaac ggtaatttga
     1021 ttattcctca taaggatcat taccataata ttaaatttgc ttggtttgat gatcacacat
     1081 acaaagctcc aaatggctat accttggaag atttgtttgc gacgattaag tactacgtag
     1141 aacaccctga cgaacgtcca cattctaatg atggatgggg caatgccagt gagcatgtgt
     1201 taggcaagaa agaccacagt gaagatccaa ataagaactt caaagcggat gaagagccag
     1261 tagaggaaac acctgctgag ccagaagtcc ctcaagtaga gactgaaaaa gtagaagccc
     1321 aactcaaaga agcagaagtt ttgcttgcga aagtaacgga ttctagtctg aaagccaatg
     1381 caacagaaac tctagctggt ttacgaaata atttgactct tcaaattatg gataacaata
     1441 gtatcatggc agaagcagaa aaattacttg cgttgttaaa aggaagtaat ccttcatctg
     1501 taagtaagga aaaaataaac taatgaaaaa tgaaagtctc gataaagagg ctttcatttt
     1561 tattatgtat atatgtaaaa ttcttgacaa gcaatattaa aaagagtaaa ctattaacta
     1621 gttaattaac cggtttatta ctttatagtg aatcaaatat acttaagaaa agaggaaaga
     1681 atgaaaatca ataaaaaata tctagctggg tcagtagcta cacttgtttt aagtgtctgt
     1741 gcttatgaac taggtttgca tcaagctcaa actgtaaaag aaaataatcg tgtttcctat
     1801 atagatggaa aacaagcgac gcaaaaaacg gagaatttga ctcctgatga ggttagcaag
     1861 cgtgaaggaa tcaatgccga acaaatcgtc atcaaaataa cagaccaagg ctatgtcact
     1921 tcacatgggg accactatca ttattacaat ggtaaggttc cttatgacgc tatcatcagt
     1981 gaagaattgc tgatgaagga tccaaactac cagctaaagg acgaggatat tatcagtgaa
     2041 atcaagggtg gttatgtgat taaggtagat ggaaaatact atgtttacct taaggatgca
     2101 gctcatgcgg ataatgtccg tacaaaagaa gaaatcaatc gacaaaaaca agagcatagt
     2161 caacatcgtg aaggtgggac tccaagaaac gatggtgctg ttgccttggc acgttcacag
     2221 ggacgctaca ccacagatga tggttatatc tttaatgctt ctgatatcat tgaagatact
     2281 ggtgatgctt atatcgttcc tcacggcgac cattaccatt acattcctaa gaatgagtta
     2341 tcagctagcg agttagctgc tgca
//
LOCUS       DAVBOD010000110         2229 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 640-05
            SAMEA1012484-rid20186543.denovo.111, whole genome shotgun sequence.
ACCESSION   DAVBOD010000110 DAVBOD010000000
VERSION     DAVBOD010000110.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012484
            Sequence Read Archive: ERR059358
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2229)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2229)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979948.1
            Genome Coverage       :: 595x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:03:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,266
            CDSs (total)                      :: 2,219
            Genes (coding)                    :: 2,091
            CDSs (with protein)               :: 2,091
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 71 of 128
            Pseudo Genes (incomplete)         :: 50 of 128
            Pseudo Genes (internal stop)      :: 33 of 128
            Pseudo Genes (multiple problems)  :: 22 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2229
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012484-rid20186543.denovo.111"
                     /strain="NIG 640-05"
                     /db_xref="taxon:1313"
     gene            <1..597
                     /locus_tag="VQ862_002129"
     CDS             <1..597
                     /locus_tag="VQ862_002129"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head morphogenesis protein"
                     /protein_id="HET3116404.1"
                     /translation="GEKVYNQDTREAKAKFYSEQLLSKISGVEPKITSDMQRIAGENK
                     LAGLEFRKKTVESLSRKIIADSLVENISLSKAVSKINDALRYTTIFDSDTFTEEYLKM
                     KQKLIAEGYKIVKVKNTWLVDGPYKGVNTVVEKDGINFEMQYHTQESFDLKNGSLHEL
                     YEKYRDTNTSDLERMKLFKEMLDLSNGLEIPKNIERVK"
     gene            599..808
                     /locus_tag="VQ862_002130"
     CDS             599..808
                     /locus_tag="VQ862_002130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000651745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3116405.1"
                     /translation="MKDIKYYRTTTNNAQVLRLIDGVMQVFDIEKKWVNSMDWFNKIF
                     FNDFTDFEEISENDAFTYIDRMVAA"
     gene            805..1218
                     /locus_tag="VQ862_002131"
     CDS             805..1218
                     /locus_tag="VQ862_002131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase"
                     /protein_id="HET3116406.1"
                     /translation="MIDIALAIAKKAHAGQVDKAGVDYIQHPLYVASQVNTEQEKAVA
                     LLHDVIEDSDITAADLFASGLSKEVVTAVQILTKKKGQSYQEYLGKVKSNNLARVVKL
                     ADLKHNSDLSRLKSVTNTDYERVKKYKNAIYYLST"
     gene            1261..1506
                     /locus_tag="VQ862_002132"
     CDS             1261..1506
                     /locus_tag="VQ862_002132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000877357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3116407.1"
                     /translation="MKYRKKPVVVEAVQWNGNNHKEVIDFAENKIWFDALGNIWIATL
                     EGDMVAKKGDYIIKGVQGEYYPCKPDIFAETYEKTEE"
     gene            1508..1759
                     /locus_tag="VQ862_002133"
     CDS             1508..1759
                     /locus_tag="VQ862_002133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000890161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3116408.1"
                     /translation="MLKKAKQLASQEFSRLAGREIKAEDCFVVWFSKTLQNWKALVST
                     NKITSSETCGDYAEITHNGDKKETYVDVYAKVSNRAIKD"
     gene            1927..>2229
                     /locus_tag="VQ862_002134"
     CDS             1927..>2229
                     /locus_tag="VQ862_002134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001001559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4355 domain-containing protein"
                     /protein_id="HET3116409.1"
                     /translation="MNEETQTVEVETVEEQKVPAEPAPQPQDEKKYTDADVDAIIDKK
                     FAKWKSEQEAKENEAKKLAKMNADEKQKYQLDQREQELADREKAIARKELTAEAKAM"
BASE COUNT          829 a          335 c          498 g          567 t
ORIGIN      
        1 ggggaaaagg tgtataatca agatacaaga gaagccaagg cgaaatttta tagcgaacaa
       61 ctattgtcca aaatttcagg agttgagcca aaaattacaa gtgatatgca acgtatcgca
      121 ggagaaaaca aattggcagg tcttgaattt aggaagaaaa cagttgagtc attatcacgt
      181 aaaattattg cagatagcct agttgaaaat ataagtttgt caaaagccgt gagtaagatt
      241 aatgacgcct taaggtacac aactattttc gattccgata cttttacaga agagtatttg
      301 aagatgaaac agaagcttat cgcagaaggt tataaaattg taaaagtaaa aaacacttgg
      361 ctagtagatg gaccatacaa aggtgtgaat acagtcgttg aaaaagatgg tatcaacttt
      421 gaaatgcagt atcatactca ggaaagtttc gacttaaaaa atggttcatt acatgaactc
      481 tatgagaagt atcgtgatac gaatacatct gatctagaac gcatgaaatt atttaaggaa
      541 atgcttgatt taagcaatgg gcttgagatt cctaaaaata tagagagggt gaagtgatat
      601 gaaagatatt aaatactacc gcacaacgac gaacaatgct caagtacttc gtttgattga
      661 tggtgtcatg caagtttttg acattgaaaa aaagtgggtt aatagcatgg attggtttaa
      721 taaaatcttt tttaatgact ttacggattt tgaagaaatt tcagaaaatg atgcatttac
      781 ttatattgac aggatggtag cggcatgatt gatattgcct tggctatcgc taaaaaagca
      841 catgcagggc aggtagataa agcgggtgtt gattacatac agcatcctct ctatgtggcc
      901 agtcaagtca acactgaaca agaaaaagct gtcgctcttt tacatgatgt gattgaggat
      961 agcgatataa ctgctgccga tttattcgcg tctggcttgt caaaggaagt tgttacagcg
     1021 gtacaaattt tgacaaagaa aaaaggtcaa agttatcaag aatatcttgg gaaagtaaaa
     1081 tcaaataatt tagcaagagt tgtaaaactt gcagatttga aacataactc agatttatca
     1141 cgtttgaaat ctgttaccaa tacagactac gagcgtgtta aaaaatataa aaatgcaatt
     1201 tattacttaa gcacctagag aaatctaagt gcttttttcg tacccagaaa ggattgagga
     1261 atgaaatacc gtaaaaaacc agtagtggtc gaggctgtgc agtggaacgg caataaccat
     1321 aaagaggtaa ttgactttgc agaaaataag atttggtttg atgcacttgg gaatatatgg
     1381 attgctacac ttgaaggtga tatggtagct aaaaaagggg attatattat caaaggcgtg
     1441 caaggagaat attatccatg caagccggat atttttgcag aaacatacga aaaaacggag
     1501 gagtaaaatg ttaaaaaaag caaaacaatt ggcatcgcaa gaattttcac gcttggcagg
     1561 tcgtgaaatc aaagcagaag actgctttgt agtttggttt agcaagaccc tgcaaaattg
     1621 gaaagctctt gttagtacga acaaaattac atcaagcgag acttgtggag attatgcaga
     1681 aatcacgcat aatggagaca agaaagagac ttatgtggat gtttacgcca aagtttcaaa
     1741 tcgtgccatt aaagattagg aggtgatcca gaatcttgac tggcaggaat agactgctat
     1801 aaatcactgt aaattgctat aaaccgtgtc agatttgatg cggtttttat attgtccgag
     1861 cattgatgac aaaaaaagcc atggaattat acagtcgggg acgactttaa aaataggagg
     1921 ttcgcaatga acgaagaaac acaaacagtc gaagtcgaaa cggttgaaga acaaaaggta
     1981 cctgcagaac ctgcaccaca accgcaagac gagaagaagt acacggatgc agatgtcgat
     2041 gctatcatcg ataagaaatt tgccaagtgg aaatcagagc aagaagccaa ggaaaacgaa
     2101 gctaagaaac tcgccaagat gaacgctgat gagaaacaga aatatcagtt agatcagcgt
     2161 gagcaagaac tagccgaccg tgaaaaggcc attgctcgca aggaattgac cgcagaagct
     2221 aaagcgatg
//
LOCUS       DAVBOD010000111         2144 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 640-05
            SAMEA1012484-rid20186543.denovo.112, whole genome shotgun sequence.
ACCESSION   DAVBOD010000111 DAVBOD010000000
VERSION     DAVBOD010000111.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012484
            Sequence Read Archive: ERR059358
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2144)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2144)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979948.1
            Genome Coverage       :: 595x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:03:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,266
            CDSs (total)                      :: 2,219
            Genes (coding)                    :: 2,091
            CDSs (with protein)               :: 2,091
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 71 of 128
            Pseudo Genes (incomplete)         :: 50 of 128
            Pseudo Genes (internal stop)      :: 33 of 128
            Pseudo Genes (multiple problems)  :: 22 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2144
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012484-rid20186543.denovo.112"
                     /strain="NIG 640-05"
                     /db_xref="taxon:1313"
     gene            71..609
                     /locus_tag="VQ862_002135"
                     /pseudo
     CDS             71..609
                     /locus_tag="VQ862_002135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399595.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
     gene            676..1086
                     /locus_tag="VQ862_002136"
     CDS             676..1086
                     /locus_tag="VQ862_002136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase family 2"
                     /protein_id="HET3116410.1"
                     /translation="MYYLPVDFYRYLIGREDQSVNEQVMIKCIDQQLKVNRLLVDQLD
                     LSQVSHPKMREYLLNHIEITTVISSTLLNRSGTAEHLAKKRQLWTYIQQKNPEVFQAI
                     RKTMLSRLTKHSVLPDRKLSNVVYQITKSVYGFN"
     gene            1202..>2144
                     /gene="pavB"
                     /locus_tag="VQ862_002137"
     CDS             1202..>2144
                     /gene="pavB"
                     /locus_tag="VQ862_002137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin-binding SSURE repeat adhesin PavB"
                     /protein_id="HET3116411.1"
                     /translation="MKFNPNQRYTRWSIRRLSVGVASVVVASGFFVLVGQPSSVRADV
                     VNPTPGQVLPEETSGTKEGDLSEKPGDTVLTQAKPEGVTGNTNSLPTPTERTEVSEET
                     NSSSLDTLFEKDEEAQKNPELTDVLKETVDTADVDGTQASPAETTPEQVKGGVKENTK
                     DSIDVPAAYLEKAEGKGPFTAGVNQVIPYELFAGDGMLTRLLLKASDNAPWSDNGTAK
                     NPALPPLEGLTKGKYFYEVDLNGNTVGKQGQALIDQLRANGTQTYKATVKVYGNKDGK
                     ADLTNLVATKNVDININGLVAKETVQKAVADNVKDSID"
BASE COUNT          656 a          411 c          478 g          599 t
ORIGIN      
        1 cgacgttgac gcggtttgaa gagattttcg aagagtataa gaaaaaatca gtcccctaaa
       61 ggagcagatt atgaagttat tgtctatcgc catttctagc tataatgcag cagcctatct
      121 tcattactgt gtggagtcgc tagtgattgg tggtgagcaa gttgggattt tgattatcaa
      181 tgacgggtct caggatcaga ctcagaaatc gctgagtgtt tagctagcaa gtatcctaat
      241 atcgttagag ccatctatca ggaaaataaa ggccatggcg gtgcggtcaa tcgtggcttg
      301 gcagaggctt ctgggcgcta ttttaaagta gttgacagtg atgactgggt ggatcctcgt
      361 gcctacttga aaattcttga aaccttgcag gaacttgaga gcaaaggtca agaggtggat
      421 gtctttgtga ccaattttgt ctatgaaaag gaagggcagt ctcgtaagaa gagtatgagt
      481 tacgagtcag tcttgcctgt tcggcagatt tttggctggg accaggtcgg aaatttctcc
      541 aaaggccagt ataccatgat gcactcgctg atttatcgga cagatttgtt gcgtgctagc
      601 cagttctaac tgcctgaaca tactttttat gtcgataatc tctttgtctt tacgcccctt
      661 cagcaggtca agaccatgta ctatctgcct gtcgatttct atcgttattt gattgggcgt
      721 gaggaccagt ctgtcaatga gcaagtgatg attaagtgca ttgaccagca actcaaggtc
      781 aatcgactct tggtagacca acttgatttg tcccaagtga gtcatcccaa aatgcgagaa
      841 tatctgctga atcatattga aatcacgacg gtgatttcca gtaccctgct caaccgatct
      901 ggaacagcgg agcatctggc aaaaaaacgc caattgtgga cctatattca gcagaaaaat
      961 ccagaagtct ttcaggctat tcgtaagacc atgttgagcc gtttgaccaa acattctgtc
     1021 ttgccagatc gcaaactgtc caatgtcgtc tatcaaatca ccaaatctgt ttatggattt
     1081 aattaatata agtgttttat aagagggatt taagaaaaat tttaactttt tcttagtcct
     1141 ttttaatttc aggagattat actagagtca tcaaataaag aaagactcta aggagaatcc
     1201 tatgaaattc aatccaaatc aaagatatac tcgttggtct attcgccgtc tcagtgtcgg
     1261 tgttgcctca gttgttgtgg ctagtggctt ctttgtccta gttggtcagc caagttctgt
     1321 acgtgccgat gtggtcaatc cgaccccagg tcaagtctta cctgaagaga catcgggaac
     1381 gaaagagggt gacttatcag aaaaaccagg agacaccgtt ctcactcaag cgaaacctga
     1441 gggcgttact ggaaatacga attcacttcc gacacctaca gaaagaactg aagtgagcga
     1501 ggaaacaaac tcttctagtc tggatacact ttttgaaaaa gatgaagaag ctcaaaaaaa
     1561 tccagagcta acagatgtct taaaagaaac tgtagataca gctgatgtgg atgggacaca
     1621 agcaagtcca gcagaaacta ctcctgaaca agtaaaaggt ggagtgaaag aaaatacaaa
     1681 agacagcatc gatgttcctg ctgcttatct tgaaaaagct gaagggaaag gtcctttcac
     1741 tgccggtgta aaccaagtaa ttccttatga actattcgct ggtgatggta tgttaactcg
     1801 tctattacta aaagcttcgg ataatgctcc ttggtctgac aatggtactg ctaaaaatcc
     1861 tgctttacct cctcttgaag gattaacaaa agggaaatac ttctatgaag tagacttaaa
     1921 tggcaatact gttggtaaac aaggtcaagc tttaattgat caacttcgcg ctaatggtac
     1981 tcaaacttat aaagctactg ttaaagttta cggaaataaa gacggtaaag ctgacttgac
     2041 taatctagtt gctactaaaa atgtagacat caacatcaat ggattagttg ctaaagaaac
     2101 agttcaaaaa gccgttgcag ataacgttaa ggacagtatc gatg
//
LOCUS       DAVBOD010000112         2142 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 640-05
            SAMEA1012484-rid20186543.denovo.113, whole genome shotgun sequence.
ACCESSION   DAVBOD010000112 DAVBOD010000000
VERSION     DAVBOD010000112.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012484
            Sequence Read Archive: ERR059358
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2142)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2142)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979948.1
            Genome Coverage       :: 595x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:03:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,266
            CDSs (total)                      :: 2,219
            Genes (coding)                    :: 2,091
            CDSs (with protein)               :: 2,091
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 71 of 128
            Pseudo Genes (incomplete)         :: 50 of 128
            Pseudo Genes (internal stop)      :: 33 of 128
            Pseudo Genes (multiple problems)  :: 22 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2142
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012484-rid20186543.denovo.113"
                     /strain="NIG 640-05"
                     /db_xref="taxon:1313"
     gene            129..1622
                     /locus_tag="VQ862_002138"
     CDS             129..1622
                     /locus_tag="VQ862_002138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000627753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent DNA methyltransferase"
                     /protein_id="HET3116412.1"
                     /translation="MITGELKNKIDQLWEILWTEGNANPLTNIEQLTYLLFMKDLDSV
                     ELGRESDAEFLGIPYEGVFPKDKPEYRWSTFKNIGDAQEVYRLMTQEIFPFIKNLKGD
                     TDDTAFSRYMREAIFQINKPATLQKAISILDVFPTRGLDVDFDNDKQSITDIGDIYEY
                     LLSKLSTAGKNGQFRTPRHIIDMMVELMQPTIKDIISDPAMGSAGFLVSASRYLKRKK
                     DEWETNTDNINHFHNQMFHGNDTDTTMLRLGAMNMMLHGVENPQISYLDSLSQDNEEA
                     DKYTLVLANPPFKGSLDYNSTSNDLLATVKTKKTELLFLSLFLRTLKPGGRAAVIVPD
                     GVLFGSSKAHKGIRQEIVENHKLDAVISMPSGVFKPYAGVSTAILIFTKTGNGGTDKV
                     WFYDMKADGLSLDDKRQPISDNDIPDIIERFHHLEKEAERQRTDQSFFVPVAEIKEND
                     YDLSINKYKEIEYEKVEYEPTEVILKKINDLEKEIQAGLAELEKLLK"
     gene            1635..>2142
                     /locus_tag="VQ862_002139"
     CDS             1635..>2142
                     /locus_tag="VQ862_002139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000756170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HET3116413.1"
                     /translation="MKKVKLGEVLSLKKGKKATVLAEQTTLSQRYIQIDDLRNNNNLK
                     FTESLNMTEALPDDILIAWDGANAGTVGYGLSGAVGSTITVLKKNERYKEKIISDYLG
                     VFLESKSQYLREHSTGATIPHLNKNILLDLQLELLGIEEQENIICILNTIKGLITKRK
                     LQLDELNLL"
BASE COUNT          755 a          322 c          426 g          639 t
ORIGIN      
        1 gtttgaagag attttcgaag agtataaaat attcaggtga cgcatagata tagttaattg
       61 aagctttgtt tgaaatctga taaaataatg atattactaa gttttaaaaa ctaaagaaaa
      121 gggaagatat gattacaggc gaattaaaaa ataaaatcga tcagctgtgg gaaattcttt
      181 ggacagaagg aaacgcaaat cctttaacaa atattgaaca gttgacttat ctcttattta
      241 tgaaagattt ggatagtgtc gagcttggac gtgaaagtga tgctgaattt ctagggattc
      301 cttatgaggg agtttttcca aaagataaac ctgaataccg ttggtcaact tttaaaaata
      361 taggagatgc tcaggaagtt tatcgtttaa tgactcagga gatttttccg tttattaaaa
      421 atctcaaggg ggatacagat gatacagcct tttcacgata tatgcgagaa gctatttttc
      481 aaataaataa acctgctacg cttcaaaagg caatttctat cttagatgtt tttccaacta
      541 ggggattaga tgtagatttt gataatgaca aacaaagtat tactgatatc ggagatatct
      601 atgaatatct gttatcaaaa ttgtcgaccg caggtaaaaa tggacagttc cgtacacctc
      661 gtcacatcat cgatatgatg gttgagttga tgcaaccgac tatcaaagat atcatctcag
      721 atcccgctat gggttctgct ggcttcttag tatctgctag ccgttactta aagcgtaaga
      781 aagatgaatg ggaaaccaat acagataata tcaatcattt tcataatcag atgtttcatg
      841 gaaatgatac ggatacgact atgttgagac ttggggcgat gaacatgatg ctacatggag
      901 tagaaaatcc acaaatcagt taccttgact cgctgtctca agataatgaa gaagccgata
      961 aatatacttt ggttttagca aatcctcctt ttaagggctc acttgactac aattcaacct
     1021 ctaatgacct tcttgcaacc gtaaaaacca aaaaaacaga attactcttt ctttctcttt
     1081 tcttgcgaac tttaaaacca ggtggacgag cagcagttat cgtacctgat ggtgtccttt
     1141 ttggttcgtc taaagctcat aaaggaattc gtcaggaaat tgtagagaat cataagcttg
     1201 atgctgtaat ctcaatgcct agtggtgtgt tcaagcctta tgctggagtt tcaactgcca
     1261 ttctcatctt tacaaaaact ggtaatggtg gtactgacaa agtctggttt tacgatatga
     1321 aagcggatgg tttaagtttg gatgataagc gacaaccgat tagcgacaat gatattccag
     1381 atattatcga acgctttcat catcttgaaa aagaagcaga acgtcagaga acggatcaat
     1441 ctttctttgt tccagttgct gagataaagg aaaatgatta tgatttgtct atcaataaat
     1501 ataaagagat tgagtatgaa aaagttgagt atgaaccaac agaggtcatc ttaaagaaaa
     1561 tcaatgattt agaaaaagaa attcaagctg gcttggctga attagaaaaa ttactcaagt
     1621 agggaggtgg ctgtatgaaa aaagtgaagt tgggggaagt cttatctcta aaaaaaggca
     1681 agaaagccac tgtacttgct gaacaaacaa ctctaagcca acgttatatt caaatagatg
     1741 atttaagaaa taataataat ttaaaattca ctgaaagttt aaatatgact gaagcactcc
     1801 cagatgatat tctgatagca tgggatggag ctaatgcagg aacagttggt tatggattat
     1861 cgggagctgt tggtagtaca attacggtct taaaaaagaa tgagcgatac aaagaaaaaa
     1921 ttatatcaga ttacttggga gtctttttgg aaagtaaatc gcagtattta cgagaacatt
     1981 caacaggtgc aacaattcct catttaaaca agaatatatt acttgattta caattagaat
     2041 tgctaggtat cgaagaacaa gagaacatta tctgtattct taatacgatt aaagggctta
     2101 ttactaaaag aaaattgcag ttagatgaac taaacttgct cg
//
LOCUS       DAVBOD010000113         1867 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 640-05
            SAMEA1012484-rid20186543.denovo.114, whole genome shotgun sequence.
ACCESSION   DAVBOD010000113 DAVBOD010000000
VERSION     DAVBOD010000113.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012484
            Sequence Read Archive: ERR059358
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1867)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1867)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979948.1
            Genome Coverage       :: 595x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:03:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,266
            CDSs (total)                      :: 2,219
            Genes (coding)                    :: 2,091
            CDSs (with protein)               :: 2,091
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 71 of 128
            Pseudo Genes (incomplete)         :: 50 of 128
            Pseudo Genes (internal stop)      :: 33 of 128
            Pseudo Genes (multiple problems)  :: 22 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1867
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012484-rid20186543.denovo.114"
                     /strain="NIG 640-05"
                     /db_xref="taxon:1313"
     gene            complement(400..780)
                     /locus_tag="VQ862_002140"
                     /pseudo
     CDS             complement(400..780)
                     /locus_tag="VQ862_002140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000443785.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS-dependent dihydroxyacetone kinase
                     phosphotransferase subunit DhaM"
     gene            complement(1202..>1867)
                     /locus_tag="VQ862_002141"
     CDS             complement(1202..>1867)
                     /locus_tag="VQ862_002141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine motif-containing protein"
                     /protein_id="HET3116414.1"
                     /translation="HQDSGNTEAKGAEAIYNRVKAAKKVPLDRMPYNLQYTVEVKNGS
                     LIIPHYDHYHNIKFEWFDEGLYEAPKGYSLEDLLATVKYYVEHPNERPHSDNGFGNAS
                     DHVQRNKNGQADTNQTEKPNEEKPQSEKPESPKPTEEPEEESPEESPEESEEPQVETE
                     KVKEKLREAEDLLGKIQNPIIKSNAKETLTGLKNNLLFGTQDNNTIMAEAEKLLALLK
                     ESK"
BASE COUNT          554 a          378 c          282 g          653 t
ORIGIN      
        1 caattaacta atttaatcac ttaaaaaaat tcgaacactt tctatacaac tgacagctca
       61 aatctttcag aatagaacaa tactaactat cgagcacccc gtattcataa atatatgtgt
      121 aattctagac ctagaattcc tataaactaa atgctttcat actcttccaa gtaattgatt
      181 gccttaaatt ttaatttttg aaggtttcta aagctagaat agccccatca caatcagttt
      241 tgattgattc acaatttaga aacactatag tttcactcct gttaaaataa aaaggaactg
      301 cataaagcaa tccctttctg attttgaaat catttactta acattttata gttgagataa
      361 tcaatagctt acctataaaa agagttatag taaaattcct tatttattga tttcaagctc
      421 cgctaactgt gtttgaataa ctgacagttc tgcaccagcc tgaagaagag cagctgcatt
      481 ataggcacct tctacaattg gaaccctgtt gatgatgata cttttatcac tgaaatcagt
      541 caccattttt aagttcattt tagcaaaacc taggtcaaaa aaggcaagta aagtatctgc
      601 tgtattttcg gaaacaaccc tatctactta atcaaaactc gttccaattc ctccgccctc
      661 ggttcctcct acataagtaa tcggaacatc tttagctact ttactaatca gttcaacaac
      721 accttctaca atgtatttgg aatgtgaaac gataacaaga ccaataccaa tactttccat
      781 caaaccaccc cagtttctaa aatagcagta aagagtaatc ctgatgagaa tgatccagga
      841 tcaatatgtc caagaaacca catgctccta agacaagagc taacagactg gccatcaata
      901 atagtattgt tctttttttc atcattactc cttaactagt gtttaactga tcaattagcc
      961 agtaaatagt ttatctttat ttacactatc tgttaagata tagtaaaatg aaataagaac
     1021 aggacagtca aatcgatttc taacaatgtt ttagaagtag aggtatacta ttctagtttc
     1081 aatctactat attttgcaca ttttcatgaa aaaaatgaga actagaactc acattctgct
     1141 ctcatttttc gttttcccgt tctcctatcc tgtttttagg agttagaaaa tgctgctacc
     1201 tttacttact ctcctttaat aaagccaata gtttttcagc ttctgccata atagtattgt
     1261 tgtcctgggt gccaaatagt aaattatttt ttaatcctgt gagagtctct ttggcattgg
     1321 acttgataat tggattctgg atttttccaa gtaaatcttc agcctctctc agtttttctt
     1381 taaccttttc agtctcgacc tgaggttctt ctgattcctc tggtgattct tctggtgatt
     1441 cttcttctgg ttcctctgtt ggttttggag actctggttt ctcgctttgc ggtttctcct
     1501 cgtttggttt ttccgtttga ttggtatcag cttgaccatt tttgtttctt tgaacatggt
     1561 cgctagcgtt accaaaacca ttatctgaat gcggacgttc gtttggatgt tcgacatagt
     1621 acttgacagt cgccaaaaga tcctcaagac tatacccctt aggtgcctca taaaggcctt
     1681 cgtcaaacca ctcaaatttg atgttatggt aatggtcata atgaggtatg attaaactac
     1741 cgtttttgac ttctacagta tattgaagat tgtaaggcat acgatcaagt ggcaccttct
     1801 tagctgcttt cacgcggttg tagatagctt ctgctccttt tgcctcagta tttcctgaat
     1861 cctgatg
//
LOCUS       DAVBOD010000114         1860 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 640-05
            SAMEA1012484-rid20186543.denovo.115, whole genome shotgun sequence.
ACCESSION   DAVBOD010000114 DAVBOD010000000
VERSION     DAVBOD010000114.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012484
            Sequence Read Archive: ERR059358
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1860)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1860)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979948.1
            Genome Coverage       :: 595x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:03:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,266
            CDSs (total)                      :: 2,219
            Genes (coding)                    :: 2,091
            CDSs (with protein)               :: 2,091
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 71 of 128
            Pseudo Genes (incomplete)         :: 50 of 128
            Pseudo Genes (internal stop)      :: 33 of 128
            Pseudo Genes (multiple problems)  :: 22 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1860
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012484-rid20186543.denovo.115"
                     /strain="NIG 640-05"
                     /db_xref="taxon:1313"
     gene            complement(3..968)
                     /locus_tag="VQ862_002142"
     CDS             complement(3..968)
                     /locus_tag="VQ862_002142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000444451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HET3116415.1"
                     /translation="MESKVTIIMQEMLPLLNNEQLLALRESLEHHLVDGKKQQKYSNN
                     NLLQLFITAKQVEGCSSKTIRYYQRTIENLFNAIKESVTQLTTDDLRSYLANYQSEKD
                     CSKANLDNIRRILSSFFAWLEQEEYIIKNPIRRIKKIKTEQNVKETYTDEHLEIMRDN
                     CENLRDLAIIDLLASTGMRVGELVQLNRSDIDFENRECVVFGKGKKERPVYFDARTKI
                     HLRNYLNDRKDSHPALFVTLVGKAQRLGIAGVEIRLRKLGDKLGIQKVHPHKFRRTLA
                     TKAIDKGMPIEQVQKLLGHSKIDTTLAYAMVNQNNVKHSHQKFIS"
     gene            complement(1086..1499)
                     /locus_tag="VQ862_002143"
     CDS             complement(1086..1499)
                     /locus_tag="VQ862_002143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000158364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system death-on-curing
                     family toxin"
                     /protein_id="HET3116416.1"
                     /translation="MTIYLTEKQIEKINALAIQRYSPNEKIQTVSSSALNMIVNLPEQ
                     FVFGKSLYPTIFDKATILFVQLIKKHVFANANKRTAFFVLVKFLQLNGYRFSVTVEEA
                     VKMCVTIAVEALTDEKMTSYSKWVSEHSVREKVKK"
     gene            complement(1496..1732)
                     /locus_tag="VQ862_002144"
     CDS             complement(1496..1732)
                     /locus_tag="VQ862_002144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000260605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HET3116417.1"
                     /translation="MVVKTRKQGNSITITIPSEFNIPSGVKYEAKLLPSGEIIFTPEE
                     LGQQVSYVSDDAFDLNLDKIFDEYDDVFKALVEK"
BASE COUNT          541 a          363 c          276 g          680 t
ORIGIN      
        1 ttttaagaga tgaatttttg gtgtgaatgc ttgacattat tttgattgac catggcatag
       61 gccagggttg tgtcaatctt gctatgacct agcagttttt ggacttgttc gataggcata
      121 cctttatcaa ttgccttagt cgctaaagtt cttctgaact tatgtgggtg aaccttttgt
      181 atgccgagtt tgtctcctaa ctttcttaag cgaatctcta caccagcaat tccaagtctc
      241 tgggcttttc caactagcgt tacaaaaaga gcagggtgac tatcttttct gtcgttaaga
      301 taatttctta aatgaatttt cgtccgagcg tcaaaatata ctggtctctc cttctttcct
      361 ttaccaaaga caacacactc tctgttttca aaatcaatat ctgaacgatt caactgtaca
      421 agctccccta cacgcatacc tgtcgatgct agtaggtcta ttattgccaa atctctcaaa
      481 ttttcacagt tatcacgcat aatttccaaa tgttcatcag tataagtttc cttcacattt
      541 tgctcagtct taattttctt tatccgtcga atgggatttt taatgatata ttcctcttgc
      601 tcaagccaag caaaaaaaga agacaatata cgcctaatat tgtctaaatt tgccttacta
      661 caatcctttt cagactggta atttgctaaa taactcctta aatcatctgt tgtgagttgt
      721 gtcacagact ctttaatagc attaaacaag ttttcaatcg tcctctggta ataacgaatt
      781 gtttttgagc tacagccctc tacctgcttg gcggtaataa atagttgcaa caggttatta
      841 ttcgaatact tctgctgctt ttttccgtct actagatgat gttctaaact ctctctcaac
      901 gctagtaatt gttcattatt taaaagaggt aacatttctt gcatgataat tgtaactttt
      961 gattccataa tttctcactt tcttattcat caataaaaag agacaatatc agtttctgca
     1021 ttacagaatt ctaatattgt ctgttcattt attttcttgt gctcattcaa atccagcata
     1081 ctaggttact ttttgacctt ttctctaaca gaatgttcag aaacccattt ggagtagctt
     1141 gtcatttttt catcagttaa agcttctact gcgatggtta cacacatttt tactgcttct
     1201 tctaccgtta cagaaaaacg atagccgttt aattgtaaaa atttgaccaa aacgaagaaa
     1261 gcagttcttt tattagcatt agcaaaaaca tgcttcttta tcaattggac aaatagtatc
     1321 gttgctttat caaaaattgt tggataaaga gacttcccaa agacaaattg ttctggtaag
     1381 ttcacaatca tatttaaggc agaagaacta actgtttgaa ttttctcatt tggagaatac
     1441 cgttgaattg ctaaagcatt tattttttca atttgctttt ctgtcagata gattgtcatt
     1501 tttccaccaa agctttgaaa acatcgtcgt attcgtcaaa tattttatct aaatttaagt
     1561 caaaggcatc atcagataca taagaaacct gctgccccaa ttcttcagga gtaaagataa
     1621 tctcaccact tggtaacaat ttcgcttcgt atttaacacc acttggaata ttaaattcac
     1681 ttggaatcgt aatggtgatt gaatttcctt gttttcttgt ttttactacc atctgatttc
     1741 ctcctttgaa gtattataac aaatcattac cgtaattaca atggcagaat atcagccaaa
     1801 atactcctgc atcagagatt tcttcaaagt ttcaagttct tccagagatt tttggattgc
//
LOCUS       DAVBOD010000115         1672 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 640-05
            SAMEA1012484-rid20186543.denovo.116, whole genome shotgun sequence.
ACCESSION   DAVBOD010000115 DAVBOD010000000
VERSION     DAVBOD010000115.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012484
            Sequence Read Archive: ERR059358
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1672)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1672)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979948.1
            Genome Coverage       :: 595x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:03:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,266
            CDSs (total)                      :: 2,219
            Genes (coding)                    :: 2,091
            CDSs (with protein)               :: 2,091
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 71 of 128
            Pseudo Genes (incomplete)         :: 50 of 128
            Pseudo Genes (internal stop)      :: 33 of 128
            Pseudo Genes (multiple problems)  :: 22 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1672
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012484-rid20186543.denovo.116"
                     /strain="NIG 640-05"
                     /db_xref="taxon:1313"
     gene            <1..510
                     /locus_tag="VQ862_002145"
     CDS             <1..510
                     /locus_tag="VQ862_002145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000795723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head morphogenesis protein"
                     /protein_id="HET3116418.1"
                     /translation="VKNEIQDYKKSDKTVSRYNTPKLFSDVSNAWDEIGRGGLSKEQL
                     VDLLESEYELGNFSSDIAKLIGVSSAYIDVSSLATSLVRHGQQYSLDEFMLIKEAVQK
                     PYLILDNSERVEKSIISYVKIPNKDKVIMEAVMVPRDEMLVIHFNKVGIRQVKKNEKN
                     MSTLYKKGK"
     gene            661..834
                     /locus_tag="VQ862_002146"
     CDS             661..834
                     /locus_tag="VQ862_002146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000356388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3116419.1"
                     /translation="MDTARIGITNVEFSGTGENDSATVKLELNIYGADTFSAIELLPK
                     ILTDIHSLSYEVD"
     gene            979..1191
                     /locus_tag="VQ862_002147"
     CDS             979..1191
                     /locus_tag="VQ862_002147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000393349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3116420.1"
                     /translation="MEEWKERFKKEYYELKERFQKLDMMIGKYEKGQLEFESKCPIDL
                     LKGQRSTMWNYLRILEQRAKIEEIKL"
     gene            1361..>1672
                     /locus_tag="VQ862_002148"
     CDS             1361..>1672
                     /locus_tag="VQ862_002148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001288018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4355 domain-containing protein"
                     /protein_id="HET3116421.1"
                     /translation="MSEEINATVSTESTETVDTQGNVDSVQEEKHERTFTRAEIGKML
                     SAERSKWEAEQEAKENEAKKLAKMNADEKQKYQLDQREQELADREKAIARKELTAEAK
                     AM"
BASE COUNT          603 a          243 c          381 g          445 t
ORIGIN      
        1 gtaaaaaatg aaatacaaga ttataagaaa agtgacaaaa ccgtttcaag atataatacc
       61 ccaaaattgt tttctgatgt tagtaacgca tgggatgaaa ttgggagggg tggattatcg
      121 aaagaacaac ttgtagactt gctagaatct gaatatgaat taggtaattt ttcgagcgat
      181 atagcaaaat tgataggagt aagttctgct tatatagatg ttagtagttt agctacttca
      241 ttagtgagac atggacaaca gtattcctta gatgaattta tgttaataaa agaggcggtt
      301 caaaaacctt atttgattct agataattca gagagggttg aaaaatcaat tatttcatat
      361 gtaaaaatac ctaacaaaga taaggtcatt atggaagcgg tgatggtgcc acgagatgaa
      421 atgctagtca ttcactttaa caaggtgggg attcgtcaag ttaaaaagaa tgaaaaaaat
      481 atgtcgacgc tttacaaaaa gggaaaataa tgctatactc ttggtaaaga tagaggttga
      541 gaatctgtca ccaacgcgcc acttatagtg ggtcgagaaa tgcaggagcc ccgacagtcc
      601 tgcctatctg tgcactaaac aatcgtttag tgcttttttt gtactcagaa aggattgaaa
      661 atggacacag caagaattgg gataactaac gtagaatttt caggaacagg cgaaaatgac
      721 tcagcgacag tgaaattaga gttaaatatt tatggggcgg atacgttcag cgcgattgag
      781 ttactaccta aaatattaac cgacattcat tcattatcgt atgaagttga ttgattgtga
      841 cattaaaagg agtgaaaaca tgtttatatg ggattgggta tcaatcgcct ttgggtggtt
      901 ggtatttttg ttgttaatat ttattattat ggccgtaatc agcggaataa ttaaaggtgt
      961 aaagaaagga acagaaaaat ggaagaatgg aaagaaagat ttaaaaaaga atactacgaa
     1021 ttgaaagaac gattccagaa gttagatatg atgattggga aatacgaaaa agggcaacta
     1081 gagtttgaat ctaaatgtcc gattgatttg ttaaaaggtc agcgttcaac catgtggaat
     1141 tatttaagaa ttctagaaca acgtgcaaaa attgaagaaa ttaaactata aaaattaacc
     1201 gcatcgaaat cgaggcggtt ttcttatgct ctaaccgtat ggaatcccgt acggttttta
     1261 tattgtccaa actgtgccga tgacattaaa agctgtactg ttccgtcgcc ggacgtaaag
     1321 cgagattatc gagtggcgac gtaatcgctg gaggacaatt atgtcagaag aaatcaatgc
     1381 aactgtatct actgaatcaa ctgagactgt cgacactcaa ggaaatgttg attcagtgca
     1441 ggaagaaaag cacgaacgaa cttttactcg tgctgaaatc ggtaagatgc tatctgccga
     1501 gcgctctaaa tgggaagctg agcaagaagc caaggaaaac gaagccaaga aacttgccaa
     1561 gatgaatgct gacgagaaac agaaatatca gttggatcag cgtgagcaag aactagctga
     1621 ccgtgagaag gctattgctc gcaaggaatt gaccgcagaa gctaaagcaa tg
//
LOCUS       DAVBOD010000116         1646 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 640-05
            SAMEA1012484-rid20186543.denovo.117, whole genome shotgun sequence.
ACCESSION   DAVBOD010000116 DAVBOD010000000
VERSION     DAVBOD010000116.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012484
            Sequence Read Archive: ERR059358
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1646)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1646)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979948.1
            Genome Coverage       :: 595x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:03:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,266
            CDSs (total)                      :: 2,219
            Genes (coding)                    :: 2,091
            CDSs (with protein)               :: 2,091
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 71 of 128
            Pseudo Genes (incomplete)         :: 50 of 128
            Pseudo Genes (internal stop)      :: 33 of 128
            Pseudo Genes (multiple problems)  :: 22 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1646
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012484-rid20186543.denovo.117"
                     /strain="NIG 640-05"
                     /db_xref="taxon:1313"
     gene            complement(242..1006)
                     /locus_tag="VQ862_002149"
     CDS             complement(242..1006)
                     /locus_tag="VQ862_002149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside phosphorylase"
                     /protein_id="HET3116422.1"
                     /translation="MIQKHAIPILEFDDNPQAVIMPNHEGLDLQLPKKCVYAFLGEEI
                     DRYAREVGANCVGEFVSATKTYPVYVVNYKDEEICLVQAPVGSAPAAQFMDWLIGYGV
                     EQIISTGTCGVLADIEENAFLVPVRALRDEGASYHYVAPSRYMEMQPEAIAAIERVLD
                     DRGIPYEEVMTWSTDGFYRETAEKVAYRKEEDCAVVEMECSALAAVAQLRGVLWGELL
                     FTADSLADLNQYDSRDWGSEAFNKALELSLASVHHL"
     gene            1228..1524
                     /locus_tag="VQ862_002150"
     CDS             1228..1524
                     /locus_tag="VQ862_002150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000450185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HET3116423.1"
                     /translation="METSISMADFYGKYQNENLELIDVREAHEFQAGHAPDAKNLPLS
                     TLEQGYKELKPDHEYYVICQGGVRSASTCQFLSSQGLTVTNVEGGMNAWPGQVE"
BASE COUNT          522 a          404 c          316 g          404 t
ORIGIN      
        1 gaagctgacc tggtttgaag agattttcga agagtatcat ttcatctcac tctaaatctt
       61 accaacataa aacgcatagt atcaaagttt tcatcacctg atatgatacg tttttctgat
      121 tttaaagatt tttcccaacc tcaacatgcc taggacaaga ggaaggtaac ctcgtttaaa
      181 catatttttg aaaagtatga gctaggcatt ttatgataaa acaaatcctt tgccagtaca
      241 actaaaggtg gtgaacactt gctaaactca gttctagcgc cttattaaaa gcttccgagc
      301 cccagtcacg actgtcgtac tggttcaagt ccgctagaga atctgctgtg aacaacaatt
      361 caccccagag aaccccacgc aattgagcta ctgccgcaag agcagaacac tccatctcca
      421 caacagcaca gtcttcttcc ttgcgataag ccaccttttc agccgtttct cggtaaaaac
      481 catctgtgga ccaggtcatg acttcttcat aaggaatccc tctatcatcc aaaactcgct
      541 caatggcagc aatagcctct ggctgcattt ccatataacg agaaggtgcc acatagtggt
      601 aactggctcc ttcatctcgc agagcgcgaa cagggactag aaaggcattt tcctctatat
      661 cagctaggac accacaggtc ccagtagaga taatctgctc cacaccatag ccaatcaacc
      721 aatccataaa ctgggctgct ggagctgaac cgacaggagc ctgaaccaga caaatctcct
      781 cgtccttgta gttcacgaca taaactggat aggtcttggt ggcagaaaca aattcgccaa
      841 cacagttcgc ccctacttcc ctcgcatagc ggtcaatctc ctcacctaaa aaagcataga
      901 cacacttctt tggcaactgc aaatccaacc cctcgtgatt gggcatgata accgcctgag
      961 gattatcatc aaactctaaa ataggaatcg catgtttctg aatcatagcc cacctcctct
     1021 aattttgtac tattgtatca aaatctgaca aagtgtcaag gaggaagctg atgaactgag
     1081 gagaaaaaca agcctacatc gtcagctgcc acagtggttt gcgcagctat atcgcagagc
     1141 ctatcctcaa gcaagcagga tttaccgtcc aaaaccttga cggcgcttat tcactataca
     1201 aaatgactaa cccagaagga gtagaatatg gaaactagta tcagcatggc tgacttttat
     1261 ggaaaatatc aaaatgaaaa tctagaactt atcgatgtcc gtgaagcaca tgaattccaa
     1321 gcaggacatg caccagatgc caaaaatctt ccattaagta ccttagagca aggctacaaa
     1381 gaactcaaac ctgaccatga atactatgtt atttgtcaag gaggagtccg ctctgcatct
     1441 acctgccaat ttctcagctc ccaaggcctc accgttacca acgtagaagg tggtatgaat
     1501 gcttggcccg gtcaagtaga ataatcaaga ggagctgggc aaaaactcaa tttcaggaga
     1561 agatgaagta atactcaatg aaaattaaag tgcaaactag gaagttagcc gcaggctgct
     1621 caaaacactg ttttaaggtt gtggat
//
LOCUS       DAVBOD010000117         1584 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 640-05
            SAMEA1012484-rid20186543.denovo.118, whole genome shotgun sequence.
ACCESSION   DAVBOD010000117 DAVBOD010000000
VERSION     DAVBOD010000117.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012484
            Sequence Read Archive: ERR059358
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1584)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1584)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979948.1
            Genome Coverage       :: 595x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:03:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,266
            CDSs (total)                      :: 2,219
            Genes (coding)                    :: 2,091
            CDSs (with protein)               :: 2,091
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 71 of 128
            Pseudo Genes (incomplete)         :: 50 of 128
            Pseudo Genes (internal stop)      :: 33 of 128
            Pseudo Genes (multiple problems)  :: 22 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1584
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012484-rid20186543.denovo.118"
                     /strain="NIG 640-05"
                     /db_xref="taxon:1313"
     gene            complement(<1..237)
                     /locus_tag="VQ862_002151"
     CDS             complement(<1..237)
                     /locus_tag="VQ862_002151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3116424.1"
                     /translation="MKILNIELANVEQTDLGFEHWVDVTYQAPILKNEYTVKLLLLME
                     CRIEDQEVIEYLVSTWKYRDLVLHSVRMYEIEKSE"
     gene            complement(508..1464)
                     /locus_tag="VQ862_002152"
     CDS             complement(508..1464)
                     /locus_tag="VQ862_002152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
                     /protein_id="HET3116425.1"
                     /translation="MDIDRNRLRTGLPQVGVQPYRQVHAHSTGNRNSTAQNEADYHYR
                     KDPELGFFSHVVGNGRVMQVGPVNNGSWDVGGGWNAESYAAVELIESHSTKEEFMADY
                     RLYIELLRNLADEAGLPKTLDTDDLAGIKTHEYCTNNQPNNHSDHVDPYPYLASWGIS
                     REQFKQDIENGLSAATGWQKNGTGYWYVHSDGSYPKDKFEKINGTWYYFDGSGYMLSD
                     RWKKHTDGNWYYFDQSGEMATGWKKIAEKWYYFDVEGAMKTGWVKYKNTWYYLDAKEG
                     AMVSNAFIQSADGTGWYYLKPDGTLADKPEFTVEPDGLVTVK"
     gene            complement(1468..>1584)
                     /locus_tag="VQ862_002153"
     CDS             complement(1468..>1584)
                     /locus_tag="VQ862_002153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001186229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin"
                     /protein_id="HET3116426.1"
                     /translation="RAKIRAELTKYNISMTDKDLDTFVESAVKQMNDAWKGR"
BASE COUNT          408 a          387 c          289 g          500 t
ORIGIN      
        1 ctcactcttt tctatctcat acatccttac cgaatgcaac acgagatcac gatacttcca
       61 agtgctgacc agatactcaa taacctcttg gtcctctatc ctgcattcca taagtaataa
      121 tagcttgacc gtgtattcat tcttcaaaat cggagcctga taagtcacat ctacccaatg
      181 ctcaaaacct aagtctgtct gctctacatt tgctagttca atatttaaaa tcttcatttt
      241 tattcctcct acttatctat tcgtaaaaga agataaaaag ttatgaaaaa atcactattt
      301 ttttattttt gacaaaacac cgtttttgac aataatcaaa aaataaaaag gagctattat
      361 taacaaaatg acgtttttgg caataatacc ctgccattcc tcctccctat tcttcaagaa
      421 aacgcttttt tgaagaatca gagcaaacaa aaaaaccgca agcctgagcc tgcggtgaaa
      481 gaacaattta gaaagtttcc tttctattta tttaactgta accaagccat ctggctctac
      541 tgtgaactct ggcttgtctg ccagtgttcc gtctggttta aggtagtacc agcctgttcc
      601 gtctgctgac tggataaaag catttgatac catggcgcct tctttagcgt ctaagtagta
      661 ccaagtgttc ttgtacttga cccagcctgt cttcatggca ccttctacat caaaatagta
      721 ccacttctca gcgattttct tccagcctgt ggccatttcg cctgattggt caaagtagta
      781 ccaattaccg tctgtgtgct tcttccagcg gtctgaaagc atatagcctg agccatcgaa
      841 ataataccag gtaccgttga ttttctcaaa cttatctttt ggataagagc cgtctgagtg
      901 tacgtaccag tagccagtgc catttttctg ccagcctgtt gcagcgctca agccgttttc
      961 gatgtcttgc ttaaactgct cacggctaat gccccaactt gcaagatatg gatatggatc
     1021 cacatggtct gagtggttgt ttggttggtt attggtacag tattcatgcg tcttgatacc
     1081 tgccaagtcg tctgtatcaa gagtcttcgg caagcctgct tcgtccgcta gattgcgtag
     1141 caattcgata tagaggcgat agtcagccat aaactcttcc ttagttgaat ggctttcaat
     1201 cagttcaacc gctgcgtaac tctcagcatt ccaaccgccc ccaacatccc aacttccgtt
     1261 gttcacagga cctacttgca tgacacggcc gtttccgaca acatgtgaaa agaaccctag
     1321 ttcagggtcc tttctatagt ggtaatcagc ttcattttga gcggttgagt tacggttgcc
     1381 tgttgagtga gcatgtactt gtcgataagg ctgcacccca acctgtggca agcctgtacg
     1441 tagtctgttt ctatcgatat ccattcccta tcgtcctttc catgcgtcat tcatctgctt
     1501 cactgctgac tctacgaagg tgtctaagtc tttgtcagtc atactgatat tatatttggt
     1561 cagctcagca cgaattttag cgcg
//
LOCUS       DAVBOD010000118         1465 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 640-05
            SAMEA1012484-rid20186543.denovo.119, whole genome shotgun sequence.
ACCESSION   DAVBOD010000118 DAVBOD010000000
VERSION     DAVBOD010000118.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012484
            Sequence Read Archive: ERR059358
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1465)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1465)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979948.1
            Genome Coverage       :: 595x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:03:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,266
            CDSs (total)                      :: 2,219
            Genes (coding)                    :: 2,091
            CDSs (with protein)               :: 2,091
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 71 of 128
            Pseudo Genes (incomplete)         :: 50 of 128
            Pseudo Genes (internal stop)      :: 33 of 128
            Pseudo Genes (multiple problems)  :: 22 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1465
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012484-rid20186543.denovo.119"
                     /strain="NIG 640-05"
                     /db_xref="taxon:1313"
     gene            84..491
                     /locus_tag="VQ862_002154"
     CDS             84..491
                     /locus_tag="VQ862_002154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013315450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HET3116427.1"
                     /translation="MARYGVYAVIPNPEQKQIVLVQEPNGAWFLPCGEIEAGENHQEA
                     LKRELIEELGFTAEIGTYYGQADEYFYSRHRDTYYYNPAYLYEATSFKEVQKPLENFN
                     HIAWFPIDEAIQNLKRGSHKWAIESWKKQHKID"
     gene            656..955
                     /locus_tag="VQ862_002155"
     CDS             656..955
                     /locus_tag="VQ862_002155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000767202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1827 family protein"
                     /protein_id="HET3116428.1"
                     /translation="MKLINTTNSHSQLVKSQLESTDATLVEVYSAGNTDVIFTQAPLH
                     YEILISNKHRAIREPEIETIQEFFLKRKIDKTSVDEANIKTLYSEKLIGISIPIK"
     gene            complement(1067..>1465)
                     /locus_tag="VQ862_002156"
     CDS             complement(1067..>1465)
                     /locus_tag="VQ862_002156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HET3116429.1"
                     /translation="SEIIAYNLSCSPNLEQVQTMLEQAFKEKHYENTILHSDQGCQYQ
                     HDSYHRFLESKGIQASMSRKGNSQDNGMMESFFGILKSEMFYGYEKTFKSLNQLEQAI
                     IDYIDYYNNKRIKVKLKGLSPVQYRTKSFG"
BASE COUNT          487 a          284 c          258 g          436 t
ORIGIN      
        1 actataataa taacgatact agataatgag gaaaatgcaa tggcaaaccc aactttcgga
       61 gaaaaaaagc gaatacagac tatattgctc gctatggcgt atatgcagtt atccctaatc
      121 ctgaacaaaa acaaattgtt cttgttcaag aaccaaatgg tgcttggttc ctaccatgtg
      181 gagaaattga agcaggtgaa aatcatcagg aagccctaaa gcgtgagttg attgaagagc
      241 ttggtttcac agcagaaatt ggtacctatt acggacaagc tgacgaatat ttctattctc
      301 gtcatcgtga tacctactac tacaatcctg cctacctcta tgaagcaact tctttcaaag
      361 aagtacaaaa gccactagaa aactttaatc atattgcctg gttccctatt gacgaggcta
      421 tccaaaacct taaacgtggt agccataaat gggccattga atcttggaaa aaacagcata
      481 agattgacta atactcttcg aaaataaaat ttaaaccacg tcagcgtcgc cttaccgtac
      541 tcaagtatag cctgcggcta gcttcctagt ttgctctttg attttcattg agtataaatc
      601 aagcgacttt attcaaaaag tgctataata gaattagaaa atcggaggaa atattatgaa
      661 gcttatcaat acgacaaact cacactcgca acttgtaaaa agtcagctag aaagtaccga
      721 tgcaaccctt gttgaggttt attctgcagg gaatacagat gttattttta cccaagctcc
      781 gcttcactat gaaatcctca tctcaaacaa acaccgtgct attcgtgagc ctgaaatcga
      841 aaccattcaa gaatttttct tgaaacgtaa aattgataag acctctgttg atgaagccaa
      901 tatcaagaca ctctactcag agaaattaat tggaatttca atcccaatca agtaagaaaa
      961 ttgagtaaaa actcgatttg agagaaagtc caataagtct ttccataata aaacgcatag
     1021 tagcaggtgc cgaaatgaac tgcaccccaa aagttagaca attaatttat ccgaaggatt
     1081 tagttctgta ttgcacaggg ctaagtcctt ttagttttac cttaattctc ttgttgttgt
     1141 aataatcaat atagtctata atggcttgtt ccaattgatt aagtgattta aatgttttct
     1201 catagccata aaacatttcg gattttaaaa tgccaaagaa agattccatc ataccgttgt
     1261 cttggctgtt tcccttgcgt gacatggatg cttgaattcc cttactctct aggaaccgat
     1321 gataagaatc gtgttggtat tgacagcctt ggtcactatg gagaatcgta ttctcatagt
     1381 gcttctcttt gaatgcctgt tccaacattg tttgtacttg ttctaaatta ggcgaacaag
     1441 aaagattata ggcgataatt tcgct
//
LOCUS       DAVBOD010000119         1455 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 640-05
            SAMEA1012484-rid20186543.denovo.120, whole genome shotgun sequence.
ACCESSION   DAVBOD010000119 DAVBOD010000000
VERSION     DAVBOD010000119.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012484
            Sequence Read Archive: ERR059358
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1455)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1455)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979948.1
            Genome Coverage       :: 595x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:03:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,266
            CDSs (total)                      :: 2,219
            Genes (coding)                    :: 2,091
            CDSs (with protein)               :: 2,091
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 71 of 128
            Pseudo Genes (incomplete)         :: 50 of 128
            Pseudo Genes (internal stop)      :: 33 of 128
            Pseudo Genes (multiple problems)  :: 22 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1455
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012484-rid20186543.denovo.120"
                     /strain="NIG 640-05"
                     /db_xref="taxon:1313"
     gene            <1..559
                     /locus_tag="VQ862_002157"
     CDS             <1..559
                     /locus_tag="VQ862_002157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000187211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HET3116430.1"
                     /translation="EVPCEIPESWEWVRLNDITSYIQRGKSPKYSNIPIYPVIAQKCN
                     QWSGFSIDLARFIDPETVHSYQKERLLRDGDLMWNSTGLGTLGRLAIYHENKNPYAWA
                     VADSHVTVIRVLSGVINCHFIYNFLSSPIVQSVIEEKASGSTKQKELLTKTIKEYLIP
                     LPPLPEQSRIVDKIEQFFAHIDALI"
     gene            616..1413
                     /gene="psrA"
                     /locus_tag="VQ862_002158"
     CDS             616..1413
                     /gene="psrA"
                     /locus_tag="VQ862_002158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000651177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type DNA invertase PsrA"
                     /protein_id="HET3116431.1"
                     /translation="MKDFELHLKKAGLAENTVRSYLYGVRFFLENYELKMEDLFEYKG
                     YLLDNFKPKTVNLRLQGVNKYLAFIGHDDLKLKFVKVQQKPFLEDVISHADYLFLKRS
                     LKKDGILKWHFVVWFLGATGARVSELIKLKVEHVEIGYFDIYSKGGKIRRLYIPKKLR
                     NSCLSWLESENRRSGYLFLNKFNEPITARGVAQQLKNYADKYKMNPKVIYPHSFRHLF
                     AKNFLAKYNDIALLADLMGHESIETTRIYLRKTATEQQNIVDKIVNW"
BASE COUNT          504 a          208 c          266 g          477 t
ORIGIN      
        1 ggaagtacct tgtgaaatac cagaaagttg ggaatgggtg aggttaaacg atataacctc
       61 ctacattcaa agagggaagt ctccaaaata ttcaaatatt cctatatacc ctgtgattgc
      121 tcagaaatgt aatcaatggt ctggcttttc tattgactta gcaagattta ttgatcccga
      181 aacagttcat agttaccaga aagaaagatt actaagggat ggtgatttaa tgtggaattc
      241 aacaggtcta ggtacgttag gacgattagc tatttaccat gaaaataaaa atccttatgc
      301 ctgggctgtt gcagatagcc atgttacagt tataagagtc ttatcggggg ttattaattg
      361 ccatttcatc tataattttc tttcctctcc tattgttcag tcagttattg aagaaaaagc
      421 gtcgggtagt acaaaacaaa aagaattatt aacgaaaact ataaaagaat atttaatccc
      481 cctcccaccc cttcctgaac aatccagaat cgttgataaa atcgaacaat ttttcgccca
      541 tattgacgca ctaatttagt ataatagttt tacgtgcggt ggaatttcta tcaaacataa
      601 gataggagtt ttacgttgaa agattttgaa ttacatttga agaaagctgg tttagctgaa
      661 aatactgtgc gttcgtacct ttatggtgtt cgatttttct tggagaatta cgaactcaaa
      721 atggaagatt tatttgaata caaaggatat ttattagaca attttaaacc taaaactgtc
      781 aatttgcgac tacaaggagt aaataaatat ctggctttta ttggtcatga tgatttgaaa
      841 ttaaaatttg tcaaagtaca gcaaaaaccg tttttagaag atgtcattag ccatgctgat
      901 tacctttttc ttaaacgtag tttgaaaaaa gatggtattt taaaatggca ttttgtcgtt
      961 tggtttttag gtgcaactgg ggctcgtgta agtgaactta ttaaactaaa agtagagcat
     1021 gtagaaatcg gttattttga catttactca aaaggtggta aaattcgtag actgtacatt
     1081 cctaaaaaat taagaaatag ttgtcttagt tggttagaat cagaaaatcg tcgaagtggt
     1141 tatttatttt tgaataaatt taacgaacca attacagcaa gaggagttgc tcaacagtta
     1201 aaaaattatg ctgataaata caaaatgaat cctaaagtaa tttaccctca ttcttttagg
     1261 catttatttg ctaagaattt tttagcgaag tataatgata ttgccttgct tgcagatttg
     1321 atgggacacg aaagtataga aactactcga atttatctaa ggaaaacagc tactgaacaa
     1381 caaaatattg tagataaaat tgttaattgg taaaaaataa caggtggtca aactgactac
     1441 ctgctatttt tgtga
//
LOCUS       DAVBOD010000120         1430 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 640-05
            SAMEA1012484-rid20186543.denovo.121, whole genome shotgun sequence.
ACCESSION   DAVBOD010000120 DAVBOD010000000
VERSION     DAVBOD010000120.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012484
            Sequence Read Archive: ERR059358
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1430)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1430)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979948.1
            Genome Coverage       :: 595x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:03:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,266
            CDSs (total)                      :: 2,219
            Genes (coding)                    :: 2,091
            CDSs (with protein)               :: 2,091
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 71 of 128
            Pseudo Genes (incomplete)         :: 50 of 128
            Pseudo Genes (internal stop)      :: 33 of 128
            Pseudo Genes (multiple problems)  :: 22 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1430
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012484-rid20186543.denovo.121"
                     /strain="NIG 640-05"
                     /db_xref="taxon:1313"
     gene            77..481
                     /locus_tag="VQ862_002159"
     CDS             77..481
                     /locus_tag="VQ862_002159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001030243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1492 domain-containing protein"
                     /protein_id="HET3116432.1"
                     /translation="MNKAKELLKELQDLDMDIQSRIDEINELEAGLLSSPKWSEVKVQ
                     GGQTRKVDDVYTQLVVMKEAIEQDTKEVINRKLELGRMINRLKNPKYRAVLRMTYINK
                     GTADSVCYDLNMSRTTYYRLKNEAVLALEEVI"
     gene            562..644
                     /locus_tag="VQ862_002160"
     tRNA            562..644
                     /locus_tag="VQ862_002160"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:593..595,aa:Tyr,seq:gta)
     gene            949..1389
                     /locus_tag="VQ862_002161"
     CDS             949..1389
                     /locus_tag="VQ862_002161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase small subunit"
                     /protein_id="HET3116433.1"
                     /translation="MSGLRIKQKRFADEYIISGNATEAYKKAGYRVSSDRVAGVEGHK
                     LLKNPKIKSYIDERLKQLDSEKIADQQEVLGYLTSVMRGETQEQTLISIGELGQTITD
                     IDVGAKDRIKAAELLGKRHRLWTDKVEADVSGTVVFANESDIPD"
BASE COUNT          478 a          226 c          357 g          369 t
ORIGIN      
        1 ttaaaaaaag ccaagacact ctctgcctca gctaatagtt ctcgcaaaga ctattatatc
       61 acaaaggaga cagagagtga acaaggctaa agagctcttg aaagagttgc aggatctgga
      121 catggacatc caaagccgta tagacgaaat taacgagctt gaggcaggtt tgctctcaag
      181 ccctaaatgg tccgaggtta aagtccaagg tggacagact agaaaagttg atgatgtcta
      241 tactcagttg gtagtgatga aagaggctat agagcaggat actaaagagg tcattaacag
      301 aaaacttgaa ttaggtagaa tgatcaatag gcttaaaaat ccaaagtaca gggcagtatt
      361 aagaatgact tacatcaaca aaggcaccgc tgatagcgtt tgttatgatt tgaatatgag
      421 tcgtacaacc tactacaggt taaaaaatga ggcggtctta gctttggaag aagttatcta
      481 acctcatagt gagcttatgg gactttttgg aacagcacgg ttctaaaaat ctgttagaat
      541 ggtagtatca agaattgaaa agagaggtct cagaattggt agatggttac ctgtaatgtc
      601 agggggctgt aatggccttg gaggttcaag tcctcccctc tcctttgagt gtttgtgtcc
      661 cagaatgagt taaatcttct gggtggggat tcacatatca ctcattaact cctatcactc
      721 attaacttaa aaatggttgc ggaagcgact ggacctcgca tgattgcgta gctaattata
      781 ttccggataa gttataagct agagggtttg attccctcag aggttttaaa gactacaaaa
      841 aataaaaaag aagtcaaaat ttaatacgca cgcaaggtag tagtcgcctt gcaagaaggt
      901 cgcacatcgt gtggcttttt tgattgtttg aaaggtggtg atggaaaatt gagtggattg
      961 agaataaaac aaaagagatt tgcagatgag tacatcatct caggtaatgc gacggaagcc
     1021 tataagaaag caggttatcg tgtttctagt gatagagtgg caggcgttga aggacataag
     1081 ttactaaaga atcctaagat taaaagctat atagatgaac gactgaaaca gcttgattct
     1141 gaaaagattg cggatcagca agaggtctta ggttatctaa cttcagtcat gcgaggagag
     1201 acgcaagaac agaccttgat aagcattgga gaactagggc agacgattac ggatatagat
     1261 gtaggagcta aagatagaat caaggcggct gaacttcttg gtaaacggca taggctttgg
     1321 acggataagg tagaggcgga tgtttctgga acggtggtgt ttgcaaatga gtcagacata
     1381 ccagattaag caaaacgata ttgtcgttga cttacctaag acagtaggag
//
LOCUS       DAVBOD010000121         1415 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 640-05
            SAMEA1012484-rid20186543.denovo.122, whole genome shotgun sequence.
ACCESSION   DAVBOD010000121 DAVBOD010000000
VERSION     DAVBOD010000121.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012484
            Sequence Read Archive: ERR059358
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1415)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1415)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979948.1
            Genome Coverage       :: 595x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:03:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,266
            CDSs (total)                      :: 2,219
            Genes (coding)                    :: 2,091
            CDSs (with protein)               :: 2,091
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 71 of 128
            Pseudo Genes (incomplete)         :: 50 of 128
            Pseudo Genes (internal stop)      :: 33 of 128
            Pseudo Genes (multiple problems)  :: 22 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1415
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012484-rid20186543.denovo.122"
                     /strain="NIG 640-05"
                     /db_xref="taxon:1313"
     gene            <1..251
                     /locus_tag="VQ862_002162"
     CDS             <1..251
                     /locus_tag="VQ862_002162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001288027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="phage scaffold protein"
                     /protein_id="HET3116434.1"
                     /translation="ELVNVVDLTSAETVSQSVAVLQKSWEQAVQKGVQEKLKGGAPMK
                     QAPVDSDGITKEEFARMGYQSRNELYQKNPELYKKLKG"
     gene            258..1103
                     /locus_tag="VQ862_002163"
     CDS             258..1103
                     /locus_tag="VQ862_002163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000123890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N4-gp56 family major capsid protein"
                     /protein_id="HET3116435.1"
                     /translation="MTAGQTKLATMVNPEVMADMVAAKLPKLIKFTPLAYVETKLEGQ
                     PGSTLTVPAWEYAGDATEIEEGQAITPDQLTTKKTTMTIKKAGKGYEITDESLLSGLG
                     DPLGQATYQLGLAIANKIDNDLVAVAKTATQHITETPTTLEAIDKALDIFEDEEDAQY
                     VAIINPKDATKLKTAVAKEWIKGSELGANMVVSGTFGEVDGVQIVRSKKVDEGKGFLV
                     KVSPSQTQTDDANKYGAFVILLKRDVAIETDRDILKKTTVITGDEHYGVYLYDPTRVV
                     KFGGA"
     gene            1115..1297
                     /locus_tag="VQ862_002164"
     CDS             1115..1297
                     /locus_tag="VQ862_002164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000054935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rho termination factor N-terminal
                     domain-containing protein"
                     /protein_id="HET3116436.1"
                     /translation="MSLLLRRHYIQEEQVNQYSDLENKTLEELKDLAKEAGVAGAYKL
                     TKAEIVEVLEELKSEI"
BASE COUNT          492 a          246 c          335 g          342 t
ORIGIN      
        1 ttgagttagt aaatgtagtt gatttgacaa gcgcagagac ggtatcgcag tctgtcgctg
       61 tattgcagaa atcatgggag caagccgtgc aaaaaggcgt tcaagaaaaa ctaaaaggcg
      121 gagctccaat gaaacaagcg ccagtcgata gtgacggtat cacaaaagaa gaatttgctc
      181 gtatgggtta tcagagtcga aatgagctct atcaaaagaa cccagagctt tataagaaat
      241 tgaaaggata atagaaaatg acagcaggac aaactaaatt agccactatg gttaatccag
      301 aagtaatggc ggatatggta gccgctaaat tacctaaatt gattaaattt acaccgctag
      361 cgtatgtaga gacaaagctt gaaggtcaac caggtagcac tttaacagtg ccagcatggg
      421 agtatgcagg agacgctact gaaattgaag aaggccaagc aattacgcca gaccaattga
      481 ctactaaaaa gactactatg accatcaaaa aagcaggtaa aggttatgaa attaccgatg
      541 agtctctttt gtcaggtctt ggtgacccac taggtcaagc gacttaccag cttggtttag
      601 ctattgccaa caagatcgat aatgatttgg tagcggtagc taaaactgca acacaacata
      661 ttacagaaac tccaacaact cttgaggcaa tcgataaagc tctagatatc tttgaggacg
      721 aagaagatgc acagtatgtt gctatcatca accctaaaga tgctactaag ctaaaaactg
      781 cagtagcaaa agaatggatt aaaggttcag agcttggagc aaatatggtt gtttctggaa
      841 ccttcggtga agttgatggt gtgcaaatcg tgcgctctaa aaaagttgat gaaggtaaag
      901 gcttccttgt taaagtgtca ccaagtcaaa ctcagacaga cgacgctaac aaatatggag
      961 cttttgttat cttgcttaaa cgtgatgtgg ctatcgaaac agaccgcgat atcttgaaga
     1021 agactaccgt aatcacaggt gatgaacact acggcgttta cctttacgac cctacacgag
     1081 ttgtaaaatt cggtggcgcg taagaggtga cgatatgagt ttattgctac gacgtcatta
     1141 tattcaagaa gagcaggtta accagtattc tgatttagag aataaaactc tagaagagtt
     1201 gaaggatcta gcgaaagaag caggtgtagc aggcgcttat aagttgacaa aagccgaaat
     1261 tgtagaagtt ttggaggaac taaaaagtga aatttaaaat caaacaagat ttctatgatt
     1321 gggaatcaaa tgtgaaacga ctggcaggag aggaacttga gattactgag gagcgctatg
     1381 ctgagctggc tgacaatatt gccagcaacg gtgtc
//
LOCUS       DAVBOD010000122         1394 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 640-05
            SAMEA1012484-rid20186543.denovo.123, whole genome shotgun sequence.
ACCESSION   DAVBOD010000122 DAVBOD010000000
VERSION     DAVBOD010000122.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012484
            Sequence Read Archive: ERR059358
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1394)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1394)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979948.1
            Genome Coverage       :: 595x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:03:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,266
            CDSs (total)                      :: 2,219
            Genes (coding)                    :: 2,091
            CDSs (with protein)               :: 2,091
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 71 of 128
            Pseudo Genes (incomplete)         :: 50 of 128
            Pseudo Genes (internal stop)      :: 33 of 128
            Pseudo Genes (multiple problems)  :: 22 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1394
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012484-rid20186543.denovo.123"
                     /strain="NIG 640-05"
                     /db_xref="taxon:1313"
     gene            268..1278
                     /gene="ccpA"
                     /locus_tag="VQ862_002165"
     CDS             268..1278
                     /gene="ccpA"
                     /locus_tag="VQ862_002165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000990602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="catabolite control protein A"
                     /protein_id="HET3116437.1"
                     /translation="MNADDTVTIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEV
                     IDRLDYRPNAVARGLASKKTTTVGVVIPNITNGYFSSLAKGIDDIAEMYKYNIVLANS
                     DEDNEKEVSVVNTLFSKQVDGIIYMGYHLTDKIRSEFSRSRTPIVLAGTVDVEHQLPS
                     VNIDYKQATIDAVSYLAKENERIAFVSGPLVDDINGKVRLVGYKETLKKAGITYSEGL
                     VFESKYSYDDGYALAERLISSNATAAVVTGDELAAGVLNGLADKGVSVPEDFEIITSD
                     DSQISRFTRPNLTTIAQPLYDLGAISMRMLTKIMHKEELEEREVLLPHGLTERSSTRK
                     RK"
BASE COUNT          439 a          228 c          317 g          410 t
ORIGIN      
        1 attttactat aactttagga gggcttagtt tcctcctttt tgtttagtct aaggtggtag
       61 caaggagcta aacctaggtt ttctatgaaa ttttttcaat caatcttcaa aaaacacttg
      121 aaagtgttta caattagtga tagaatggaa taagtagaaa tatgaaaacg aaattttcac
      181 atcttcactt ttgtaagtag atatagagct tcaatcagca cctctacttg taaaagaata
      241 tgtgagatag aaaggacagg aaaaggaatg aatgcagatg atacagtaac catttatgat
      301 gtcgctcgtg aagcaggtgt ttccatggcg acggtcagcc gtgtggtcaa tggcaataaa
      361 aatgtaaaag agaatacccg taaaaaagtg ctagaggtaa ttgatcgttt ggattatcgt
      421 ccaaatgcag ttgcgcgtgg tcttgcaagt aaaaagacaa ccactgtcgg tgtcgtgatt
      481 ccaaatatta ccaatggtta tttttcgagt ttggctaagg ggattgatga tattgcagaa
      541 atgtacaagt acaatattgt cctagctaat agcgatgaag ataacgagaa agaagtttct
      601 gttgtcaata ccctcttttc aaagcaggta gatggcatta tctatatggg ttatcacttg
      661 acagataaaa ttcgctcaga attttcgcgc tcacgtactc cgattgttct cgcaggaact
      721 gtcgatgttg agcaccagtt gccaagtgtc aatattgact ataagcaagc aacaattgat
      781 gcagtgagtt accttgctaa agaaaatgag cgtattgctt tcgttagcgg tccgctagtg
      841 gatgacatca atggtaaggt tcgtttagtt ggctacaagg aaaccttgaa aaaagcagga
      901 atcacttata gtgagggttt ggtatttgaa tctaaatata gctatgatga tggttacgcc
      961 ttagcagagc gtttgatttc atcaaatgca actgcagcag ttgtgacagg tgatgagttg
     1021 gcagcaggag tcttgaacgg tttggctgat aaaggtgttt ctgtgccaga agattttgaa
     1081 attattacta gtgatgattc acaaatctca cgctttaccc gtccaaactt gacaacgatt
     1141 gcccaacctc tttatgacct tggtgctatt agtatgcgta tgttgaccaa gattatgcat
     1201 aaggaagagt tggaagaacg tgaagttctc ttacctcatg gtttgacaga acgtagctca
     1261 acacgaaaac gtaaatagaa aaaatcaggg aatcgagaag atttcctgat tttgtgctct
     1321 taaacaagag atgttgactt aatgaatacc atagagcgga ctaggcggct ggttaaaggc
     1381 tgcgcaacac actg
//
LOCUS       DAVBOD010000123         1326 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 640-05
            SAMEA1012484-rid20186543.denovo.124, whole genome shotgun sequence.
ACCESSION   DAVBOD010000123 DAVBOD010000000
VERSION     DAVBOD010000123.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012484
            Sequence Read Archive: ERR059358
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1326)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1326)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979948.1
            Genome Coverage       :: 595x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:03:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,266
            CDSs (total)                      :: 2,219
            Genes (coding)                    :: 2,091
            CDSs (with protein)               :: 2,091
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 71 of 128
            Pseudo Genes (incomplete)         :: 50 of 128
            Pseudo Genes (internal stop)      :: 33 of 128
            Pseudo Genes (multiple problems)  :: 22 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1326
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012484-rid20186543.denovo.124"
                     /strain="NIG 640-05"
                     /db_xref="taxon:1313"
     gene            40..351
                     /locus_tag="VQ862_002166"
     CDS             40..351
                     /locus_tag="VQ862_002166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head-tail adapter protein"
                     /protein_id="HET3116438.1"
                     /translation="MSIELLKKLTGEEDTQLLMLLQTRATNLILSETNRTSLTPALSL
                     LIPEVAIELHNRSGAEGERSRTEGGIAVVYGEKGLSTGLLQRIRMHRLARVAGHVFEA
                     E"
     gene            332..670
                     /locus_tag="VQ862_002167"
     CDS             332..670
                     /locus_tag="VQ862_002167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000478943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3116439.1"
                     /translation="MFLKQSRLKPYPMRRFEKTVTEEGVAKEGYAKEAETVRLELWPA
                     SSKLQSELYGERVNDILNANANKSATIKVKDGVCIDSQTEVTHRVISKKVYTHHQVLE
                     LERVRATRGR"
     gene            645..1160
                     /locus_tag="VQ862_002168"
     CDS             645..1160
                     /locus_tag="VQ862_002168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000015942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 gp10 family phage protein"
                     /protein_id="HET3116440.1"
                     /translation="MSGLRGADRLIAKCRRLASKKTGEDIVLRAVHNATIKVVQADAR
                     RLAPARDGELITSIKTRAKMDGDRAIGEVYTNLKYAPYVEFGTGPIGQANHSGISPEV
                     SVTYKSNPWYVHEDQINVGPYHFQKIGEFYKMYGQPAQPYLYPALRDNQERVSKNISN
                     YVRRKIREQIK"
     gene            1157..>1326
                     /locus_tag="VQ862_002169"
     CDS             1157..>1326
                     /locus_tag="VQ862_002169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000608233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3116441.1"
                     /translation="MINIKPVIYKELQKVADNVTDTYPSDWETFPVVIFLEEQNKPGD
                     WFDDQEQKSSIR"
BASE COUNT          421 a          248 c          322 g          335 t
ORIGIN      
        1 aaatcctccc tgaacctgag ttcttagaag aggattgata tgtctataga gttgctgaag
       61 aaattaacag gcgaagaaga tactcagctt ctcatgttgc tccaaacaag agctacaaat
      121 cttatcttgt cagagactaa tcgcacatct ttgacacctg ctttaagtct tttgatacct
      181 gaggttgcta tcgagctcca caaccgctca ggagcggaag gagagcgttc tagaaccgag
      241 ggtggtatag cagtagtcta cggagaaaaa ggcctgtcta cgggtctttt acagcgcata
      301 cgcatgcaca ggctagcaag ggtggcaggt catgtttttg aagcagagta gactgaaacc
      361 ttatccaatg cgacggtttg aaaagactgt cacagaggaa ggtgtcgcaa aagaagggta
      421 tgccaaggaa gctgagacag tccgtcttga attgtggcca gctagtagca agctacaatc
      481 tgaattgtat ggcgagcgtg tcaatgatat tttgaacgca aatgccaaca agtcagctac
      541 tatcaaagta aaagatggtg tgtgtatcga tagtcagacg gaagtgactc atagggttat
      601 ttctaaaaag gtctacacac atcatcaagt tttggagtta gagcgtgtca gggctacgag
      661 gggcagatag gcttatagct aaatgtagac gattggctag taaaaaaact ggcgaggata
      721 tcgtcttacg tgcggtgcac aatgctacta taaaggttgt ccaagcagat gcaagaagac
      781 tcgcaccagc gagagatgga gagcttataa ctagtatcaa aactagggca aaaatggacg
      841 gagatagggc tataggcgaa gtttacacca accttaaata cgctccttat gttgagtttg
      901 gaacgggacc aataggacaa gctaaccatt cgggtatctc tccagaggtc agcgtaactt
      961 acaagtctaa tccttggtat gtgcatgaag accaaatcaa tgtaggaccg taccactttc
     1021 aaaagattgg ggagttctac aagatgtatg gtcaacctgc tcagccttat ctttatccag
     1081 ctttgagaga caatcaagag cgtgtgtcta agaatatttc gaattatgtc cgtagaaaga
     1141 taagagaaca aataaaatga ttaatatcaa gcctgttatt tataaagaat tgcaaaaggt
     1201 tgcagataat gtgaccgata cttatcctag cgattgggag actttcccag tcgttatttt
     1261 tttggaagaa caaaacaagc cgggtgattg gtttgatgac caggaacaaa aatcctctat
     1321 ccgcta
//
LOCUS       DAVBOD010000124         1326 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 640-05
            SAMEA1012484-rid20186543.denovo.125, whole genome shotgun sequence.
ACCESSION   DAVBOD010000124 DAVBOD010000000
VERSION     DAVBOD010000124.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012484
            Sequence Read Archive: ERR059358
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1326)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1326)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979948.1
            Genome Coverage       :: 595x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:03:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,266
            CDSs (total)                      :: 2,219
            Genes (coding)                    :: 2,091
            CDSs (with protein)               :: 2,091
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 71 of 128
            Pseudo Genes (incomplete)         :: 50 of 128
            Pseudo Genes (internal stop)      :: 33 of 128
            Pseudo Genes (multiple problems)  :: 22 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1326
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012484-rid20186543.denovo.125"
                     /strain="NIG 640-05"
                     /db_xref="taxon:1313"
     gene            40..351
                     /locus_tag="VQ862_002170"
     CDS             40..351
                     /locus_tag="VQ862_002170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head-tail adapter protein"
                     /protein_id="HET3116442.1"
                     /translation="MSIELLKKLTGEEDTQLLMLLQTRATNLILSETNRTSLTPALSL
                     LIPEVAIELHNRSGAEGERSRTEGGIEVVYGENGLSTGLLQRIRMHRLARVAGHVFEA
                     E"
     gene            332..670
                     /locus_tag="VQ862_002171"
     CDS             332..670
                     /locus_tag="VQ862_002171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000478943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3116443.1"
                     /translation="MFLKQSRLKPYPMRRFEKTVTEEGVAKEGYVKEAETIRLELWPA
                     SSKLQSELYGERVNDILNANANKSATIKVKDGVCIDSQTEVTHRVISKKVYTHHQVLE
                     LERVRATRGR"
     gene            645..1160
                     /locus_tag="VQ862_002172"
     CDS             645..1160
                     /locus_tag="VQ862_002172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000015942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 gp10 family phage protein"
                     /protein_id="HET3116444.1"
                     /translation="MSGLLGADRLIAKCRRLASKKTGEDIVLRAVHNATIKVVQADAR
                     RLAPARDGELITSIKTRAKMDGDKAIGEVYTNLKYAPYVEFGTGPKGQASHSGISPEV
                     SVTYKSSPWYVHEDQINVGPYHFQKIGEFYKMYGQPAQPYLYPALRDNQERVSKNISN
                     YVRRKIREQIK"
     gene            1157..>1326
                     /locus_tag="VQ862_002173"
     CDS             1157..>1326
                     /locus_tag="VQ862_002173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000608233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3116445.1"
                     /translation="MINIKPVIYKELQKVADNVTDTYPSDWETFPVVIFLEEQNKPGD
                     WFDDQEQKSSIR"
BASE COUNT          427 a          246 c          317 g          336 t
ORIGIN      
        1 aaatctttcc taaacctgag ttcttagaag aggattgata tgtctataga gttgctgaag
       61 aaattaacag gcgaagaaga tactcagctt ctcatgttgc tccaaacaag ggctacaaat
      121 cttatcttgt cagagactaa tcgcacatct ttgacacctg ctttaagtct tttgatacct
      181 gaggttgcta tcgagctcca caaccgctca ggagcggaag gagagcgttc tagaaccgaa
      241 ggtggtatag aagtagtcta cggagaaaac ggcctgtcta cgggcctttt acagcgtata
      301 cgtatgcata gactagcaag ggtggcaggc catgtttttg aagcagagta gactgaaacc
      361 ttatccaatg cgacggtttg aaaagactgt tactgaggaa ggtgtcgcaa aagaaggata
      421 tgtcaaggaa gctgagacaa tccgtcttga gttgtggcca gctagtagta aactacagtc
      481 tgaattgtat ggcgagcgtg tcaatgatat tttgaacgca aatgccaaca agtcagctac
      541 aatcaaagtg aaagatggtg tgtgtatcga tagccagaca gaagtgactc acagggttat
      601 ttctaaaaag gtctacacac atcatcaagt tttggagtta gagcgtgtca gggctactag
      661 gggcagatag gctcatagct aaatgtagac gattggctag taaaaaaact ggcgaggata
      721 tcgtcttacg tgcggtacac aatgctacta taaaggttgt ccaagcagat gcaagaagac
      781 tcgcaccagc gagagatgga gagcttataa ctagtatcaa aactagggca aaaatggacg
      841 gagataaggc tataggcgag gtttacacca acctaaaata cgctccttac gttgagtttg
      901 gaacgggacc aaaaggacaa gctagccatt ctggtatctc tccagaggtc agcgtaactt
      961 acaagtctag tccgtggtat gtgcatgaag accaaatcaa tgtaggacct taccactttc
     1021 aaaagattgg ggagttctac aagatgtatg gtcaacctgc ccagccttat ctttatccag
     1081 ctttgagaga caatcaagag cgtgtgtcta agaatatttc gaattatgtc cgtagaaaga
     1141 taagagaaca aataaaatga ttaatatcaa gcctgttatt tataaagaat tgcaaaaggt
     1201 cgcagataat gtgactgata cttatcctag cgattgggag actttcccag tcgttatttt
     1261 tttagaagaa caaaacaagc cgggtgattg gtttgatgac caggaacaaa aatcatctat
     1321 ccgcta
//
LOCUS       DAVBOD010000125         1231 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 640-05
            SAMEA1012484-rid20186543.denovo.126, whole genome shotgun sequence.
ACCESSION   DAVBOD010000125 DAVBOD010000000
VERSION     DAVBOD010000125.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012484
            Sequence Read Archive: ERR059358
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1231)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1231)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979948.1
            Genome Coverage       :: 595x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:03:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,266
            CDSs (total)                      :: 2,219
            Genes (coding)                    :: 2,091
            CDSs (with protein)               :: 2,091
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 71 of 128
            Pseudo Genes (incomplete)         :: 50 of 128
            Pseudo Genes (internal stop)      :: 33 of 128
            Pseudo Genes (multiple problems)  :: 22 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1231
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012484-rid20186543.denovo.126"
                     /strain="NIG 640-05"
                     /db_xref="taxon:1313"
     gene            <1..1136
                     /locus_tag="VQ862_002174"
     CDS             <1..1136
                     /locus_tag="VQ862_002174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000212166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3116446.1"
                     /translation="AKMGLATAAEFAHSVAAGVATAATWAFNAALAVLTSPITLVIAA
                     IAALIGIGVLLYQNWDTVVEFAKTAWQGLCDFISGICQAIGEFFSGLWTKLQEIFEPI
                     GQWFSEKFQQAWDAIGNIFGNLGSWFGGRWNDSKNALAEANTWLGDKFKSGRDKVNSA
                     FEKVGSWFGDRWNDIKDGVKEADTWFGEKFESAKKKTQNPFQKIGSWFGDRWKDMQDA
                     LKEIPNWFKNLFNDAMDNAKNIVKSGIDKLKSFFNFDWSLPKIKLPHFNISGSFSLMP
                     PRIPSFSVDWYARGGVFNSPSIIGVGEAGQEAVMPLERNTGWISILAQKLAERMPANN
                     VPTGYSLPAGDIVIQIAGHEFGRVAIQEINKEHERAGQTLLKI"
BASE COUNT          370 a          221 c          300 g          340 t
ORIGIN      
        1 cagcgaaaat gggattagca accgcggcgg aatttgcaca ttctgttgca gcaggagtcg
       61 ctacagctgc aacatgggct tttaatgcag cgttagcagt tttgacaagt ccaataacct
      121 tagttattgc agcaatcgca gccttaattg gtatcggtgt cttgctctac caaaattggg
      181 acactgttgt tgagtttgct aaaactgcat ggcaaggact atgtgatttt atcagtggta
      241 tttgtcaagc gattggcgaa tttttcagcg gtctatggac gaaactccaa gaaatctttg
      301 agccaatagg tcaatggttt agcgagaagt tccagcaagc atgggatgct attggaaata
      361 tatttggcaa cttaggctct tggtttggtg gccgttggaa tgattctaaa aacgcacttg
      421 ccgaagcaaa tacttggctt ggtgataagt tcaagtcagg tcgggataaa gtgaactcag
      481 cttttgaaaa agttggctct tggttcggtg accgttggaa tgatatcaaa gatggagtga
      541 aagaagctga tacatggttt ggagagaaat ttgagagtgc aaaaaagaaa actcagaatc
      601 ctttccaaaa aatcggttct tggtttggcg atagatggaa agatatgcaa gatgccttga
      661 aagaaatccc caactggttc aagaatctgt ttaatgatgc aatggataat gctaaaaaca
      721 tcgttaaaag tggtatcgat aaactaaaaa gcttctttaa ctttgattgg agcttaccaa
      781 aaatcaaact ccctcacttt aatatatctg gtagcttcag cttgatgcct cctagaattc
      841 catcattctc tgtagattgg tatgcacgag gtggtgtatt caactctcct agcatcattg
      901 gggtcggaga agctggtcaa gaagcggtaa tgcctcttga acggaataca ggatggattt
      961 ctatcttggc tcaaaaactg gctgaaagaa tgcctgctaa taatgtacct acaggttatt
     1021 cattaccggc tggcgacatc gttatccaaa tcgcaggaca tgagttcggt cgggtagcaa
     1081 tccaagaaat caacaaggag catgaacgag caggtcaaac cttgctcaag atttaggagg
     1141 ttaaatggca caattgacaa tcaatggggt ggctgtgaag cctcccaaat cttttcaagt
     1201 cggtattcaa gatatcgatg gagagacagg g
//
LOCUS       DAVBOD010000126         1044 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 640-05
            SAMEA1012484-rid20186543.denovo.127, whole genome shotgun sequence.
ACCESSION   DAVBOD010000126 DAVBOD010000000
VERSION     DAVBOD010000126.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012484
            Sequence Read Archive: ERR059358
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1044)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1044)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979948.1
            Genome Coverage       :: 595x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:03:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,266
            CDSs (total)                      :: 2,219
            Genes (coding)                    :: 2,091
            CDSs (with protein)               :: 2,091
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 71 of 128
            Pseudo Genes (incomplete)         :: 50 of 128
            Pseudo Genes (internal stop)      :: 33 of 128
            Pseudo Genes (multiple problems)  :: 22 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1044
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012484-rid20186543.denovo.127"
                     /strain="NIG 640-05"
                     /db_xref="taxon:1313"
     gene            <1..550
                     /locus_tag="VQ862_002175"
     CDS             <1..550
                     /locus_tag="VQ862_002175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001220748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HET3116447.1"
                     /translation="ETTSYPIYEIPEAWRYIKFASLVNFRIGKTPPRSEATFWGTEIP
                     WVSISDMPISGYVTNTRESISKLALKSKKIDISPKGTLLMSFKLSIGKVAILDIPATH
                     NEAIISIFPYANKENIIRDYLMIFLPLISTLGDSKDAIKGKTLNSTSISELLIPISNH
                     EEMKRIISKVDLLFQKVSQLFE"
     gene            complement(498..1043)
                     /locus_tag="VQ862_002176"
     CDS             complement(498..1043)
                     /locus_tag="VQ862_002176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001104691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HET3116448.1"
                     /translation="MNWVVIKIKDIFSMNTGLSYKKGDLSINNKGVRIIRGGNIKPLE
                     FSLLDNDYYIDTQFISSEQVYLKHNQLITPVSTSLEHIGKFARIDKDYDGVVAGGFIF
                     QLTPFESSEIISKFLLFNLSSPLFYKQLKAITKLSGQALYNIPKTTLSELLIPLAPFE
                     EQELITQKVEKLFEKVNQLWK"
BASE COUNT          375 a          167 c          149 g          353 t
ORIGIN      
        1 cgaaacaacc tcttatccta tatatgaaat cccagaagca tggagatata ttaaatttgc
       61 tagcctagtt aacttcagaa taggaaaaac tcctccacgc agtgaagcta ctttttgggg
      121 aactgaaata ccttgggtat ctatatcaga tatgcctata tctggttatg taactaatac
      181 gagagaatct atttctaaat tagcattaaa atcaaagaaa atagacattt cacctaaagg
      241 aactttatta atgagtttta aattatctat tggaaaagtt gccatattgg atattcctgc
      301 cactcataat gaagccatta tatcgatatt cccctatgct aataaagaaa atattatcag
      361 agattactta atgatatttt tgccacttat ctctacttta ggtgattcaa aagatgctat
      421 caaagggaaa acattaaata gtaccagtat ctccgaatta ttaatcccta tttctaatca
      481 tgaagagatg aaaagaatca tttccaaagt tgatttactt tttcaaaaag tttctcaact
      541 ttttgagtaa taagttcctg ttcctcaaaa ggagctaacg gaattaatag ctcgctcagt
      601 gtagttttag gaatattata taaagcttga cctgatagtt tagttattgc tttcaattgt
      661 ttataaaata acggagaaga caagttaaat aatagaaatt ttgaaataat ctctgaactt
      721 tcgaatggtg ttaattggaa aataaatcca ccagccacaa caccatcata gtctttatcg
      781 attcttgcaa actttccaat atgttctaaa gaggttgata caggtgttat tagctgatta
      841 tgttttaaat aaacttgttc agaggagatg aattgtgtat caatgtagta atcattatcc
      901 aacagagaaa attctaaagg cttaatatta ccaccacgta taattctaac acctttatta
      961 ttaatgctta aatcgccctt cttgtaagaa agacctgtat tcattgaaaa aatatctttt
     1021 atttttataa caacccaatt cata
//
LOCUS       DAVBOD010000127         1022 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 640-05
            SAMEA1012484-rid20186543.denovo.128, whole genome shotgun sequence.
ACCESSION   DAVBOD010000127 DAVBOD010000000
VERSION     DAVBOD010000127.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012484
            Sequence Read Archive: ERR059358
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1022)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1022)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979948.1
            Genome Coverage       :: 595x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:03:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,266
            CDSs (total)                      :: 2,219
            Genes (coding)                    :: 2,091
            CDSs (with protein)               :: 2,091
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 71 of 128
            Pseudo Genes (incomplete)         :: 50 of 128
            Pseudo Genes (internal stop)      :: 33 of 128
            Pseudo Genes (multiple problems)  :: 22 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1022
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012484-rid20186543.denovo.128"
                     /strain="NIG 640-05"
                     /db_xref="taxon:1313"
     gene            <1..127
                     /locus_tag="VQ862_002177"
     CDS             <1..127
                     /locus_tag="VQ862_002177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001828718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="bacteriocin transporter"
                     /protein_id="HET3116449.1"
                     /translation="GHLKKDYIEFKRVGIFDGKAVEVTLREPYSRDLLQVVKSIK"
     gene            complement(424..711)
                     /locus_tag="VQ862_002178"
                     /pseudo
     CDS             complement(424..711)
                     /locus_tag="VQ862_002178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            710..973
                     /locus_tag="VQ862_002179"
                     /pseudo
     CDS             710..973
                     /locus_tag="VQ862_002179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT          379 a          160 c          178 g          305 t
ORIGIN      
        1 aggacatctc aaaaaagact acattgaatt taaacgtgtt ggtatctttg atgggaaagc
       61 agtagaagtt actcttcgag aaccttattc gagagatcta ctgcaggttg tcaagtcaat
      121 aaagtaactg acaccacgag tataattatt agaaacgtgg aatcttatta aattttataa
      181 taaatatatt aaatgaaaaa ttattagata taaacttatg taataaaaca ttgaggaaat
      241 aataaaaatc tatgggtaat gttctgaaag tacttttagg ttaggagaga aatataatga
      301 tttttgaaaa ttgattcaaa aaatagcgaa ttgtagaaaa cgcttaacaa atggtgtata
      361 atagacttcc agcgaaacaa aatatgctac aataaaccta tgaattataa agtaacctta
      421 tactcatctg tcttcacaaa gcattctagt ccatctccga ttaacgatgg actttatcat
      481 ctccttctcc agtccttgta tgacatcttc caaagttcga aaggctttat tcttaaatcc
      541 acgtttacga atctctttcc acacttattc aatggggttc atttctggtg tgtatggagg
      601 aataaatgca aagccaatat tagtcggaat ctttaaggca cttgatttat gccatatagc
      661 attgtccata acgaataaaa gataatcatc tggataagct tgtgaaagct tggctgacag
      721 tggttatcaa gggctcatga agatatatct tcaagcacaa actccacgta aatccagcaa
      781 actcaagccg ctaacagctg aagataaagc ctataaccat gcgctatcta aggagagaag
      841 caaggttgag aatatttttg ccaaagtaaa aacgtttaaa atgttttcaa caacctatcg
      901 aaatcatcgt aaacgcttcg gattacgaat gaatttgatt gctgatatta tcaatcatga
      961 actaggattc tagttttgca ggaagtctaa taaatgtata agaaaaagga ggaaaaagga
     1021 tg
//
LOCUS       DAVBOD010000128         1003 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 640-05
            SAMEA1012484-rid20186543.denovo.129, whole genome shotgun sequence.
ACCESSION   DAVBOD010000128 DAVBOD010000000
VERSION     DAVBOD010000128.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012484
            Sequence Read Archive: ERR059358
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1003)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1003)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979948.1
            Genome Coverage       :: 595x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:03:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,266
            CDSs (total)                      :: 2,219
            Genes (coding)                    :: 2,091
            CDSs (with protein)               :: 2,091
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 71 of 128
            Pseudo Genes (incomplete)         :: 50 of 128
            Pseudo Genes (internal stop)      :: 33 of 128
            Pseudo Genes (multiple problems)  :: 22 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1003
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012484-rid20186543.denovo.129"
                     /strain="NIG 640-05"
                     /db_xref="taxon:1313"
     gene            77..945
                     /locus_tag="VQ862_002180"
                     /pseudo
     CDS             77..945
                     /locus_tag="VQ862_002180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT          319 a          208 c          164 g          312 t
ORIGIN      
        1 cctattttgt tgtagaaaaa aagtcccata tgacctataa tgaaaagcga ccaaacaact
       61 cattagaaag attcatatgg aacaattaca ttttatcaca aaactgctcg atattaaaga
      121 cccaaacatc aagattctag atatcatcaa tatggatacc cacaaagaaa ttatcgctaa
      181 gctggattat gaggctccat cttgccctga ttgtggaagt ctaatgaaga aatatgactt
      241 tcaaaaaccg tctaagatcc cttatcttga aacgactggt atgcctacta gaattctcct
      301 tagaaagcgt cgattcaagt gctatcactg ttcaaaaatg atggtcgctg aaacttctat
      361 cgtcaagaag aatcaccaaa tccctcgtat catcaaccaa aagattgctc aaaagttaat
      421 tgaaaagatt tctatgactg atattgccca tcagctttcc atctcaactt caactgttat
      481 tcgtaagctc aatgattttc actttaaaca tgatttttct tgtcttcctg agattatgtc
      541 ttgggatgag tatgctttta caaagggaaa gatgagcttc attgcgcaag attttaacaa
      601 tctcaatatc atcactgttc ttgagggtag aacacaagct atcattcgaa atcactttct
      661 tcgctacgat agagttgtcc gatgtcgcgt caaaatcatt actatggata tgtttagccc
      721 ttactatgac ttggctaaac agtttcgctt tcaaatttct aggctcaggc tgaaacagtc
      781 tcccagactg tttcactccc gaatgctaaa atcgtgttgg atcgctttca cattgtacaa
      841 catcttagcc gtgctatgag tcgtgtgcgt gttcaaatca taaatcagtt tcatcgaaaa
      901 tcccatgaat acaaggctat caagcgctac tggaaactca ttcaatagga tagtcgtaaa
      961 ctgagtgata aacattttta tcgtcctact tttcgtatgc att
//
LOCUS       DAVBOD010000129          973 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 640-05
            SAMEA1012484-rid20186543.denovo.130, whole genome shotgun sequence.
ACCESSION   DAVBOD010000129 DAVBOD010000000
VERSION     DAVBOD010000129.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012484
            Sequence Read Archive: ERR059358
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 973)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 973)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979948.1
            Genome Coverage       :: 595x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:03:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,266
            CDSs (total)                      :: 2,219
            Genes (coding)                    :: 2,091
            CDSs (with protein)               :: 2,091
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 71 of 128
            Pseudo Genes (incomplete)         :: 50 of 128
            Pseudo Genes (internal stop)      :: 33 of 128
            Pseudo Genes (multiple problems)  :: 22 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..973
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012484-rid20186543.denovo.130"
                     /strain="NIG 640-05"
                     /db_xref="taxon:1313"
     gene            <1..>973
                     /locus_tag="VQ862_002181"
     CDS             <1..>973
                     /locus_tag="VQ862_002181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001174798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="peptidase S74"
                     /protein_id="HET3116450.1"
                     /translation="LSRTKNELAGVKSAQATYEETTTRRLSELTNLANGKASKSELTQ
                     TAEELASRIASVHLGRRNLLKGTKDLARYKPVSEYNGFKVIRTVAGATRYQDSYVERT
                     VIPTAGTEYIAIFYARASENDYPVRCHFYNPNTVVSSENSSGYKSRSSDGLSIIRLST
                     DWQLCWVKWTQTATDQAKTVIIGRHGPQVGGKEGVWVEICAPAIFEGNLAGDWSPAYE
                     DQDERVSAVESNFKQRADSLDAGVRSLTEGLRTKVDISALNVTAENIRQSVKSLETDT
                     QNKLNQKLSQAEFEVRAGSIRQEILNATKDKASKSELTQTAEELSSK"
BASE COUNT          295 a          212 c          258 g          208 t
ORIGIN      
        1 cacttagccg gactaaaaat gaactggctg gcgtgaagtc agcgcaagcg acgtatgagg
       61 agacgacgac tcgtagactg tcagaactga ccaacttggc caatggtaaa gccagcaagt
      121 cagaactcac gcagacagct gaggagctag ctagtcggat tgcgagtgtg cacttagggc
      181 gcagaaatct gctgaaaggc acaaaagatc ttgcgagata caagccggtt agtgaatata
      241 atggttttaa agttatcaga acagtcgcag gagcaactag atatcaggat agctatgtgg
      301 aaagaaccgt tataccaacg gctgggacag agtatatagc tatcttttat gcacgagcca
      361 gtgaaaatga ctatcctgtg cgctgtcatt tttacaatcc taacacggtt gtatcatcag
      421 aaaacagcag cggatataag tcaaggtcgt cagatggctt gtctattatc cgtctctcga
      481 cagactggca gttgtgctgg gttaaatgga cccaaaccgc aacagatcaa gccaagacgg
      541 tcatcattgg ccgccatggc cctcaagtag gcggtaaaga gggggtatgg gttgaaatct
      601 gcgcccctgc catttttgag ggaaatcttg caggtgactg gtcaccagca tacgaagacc
      661 aagacgaacg tgtctcagcg gtcgaatcca actttaaaca gcgtgctgat tcactcgacg
      721 ctggtgtgag aagcttgact gaagggctta gaaccaaagt tgatatcagc gcactcaacg
      781 tgactgctga gaatattagg caatctgtga agagtcttga gacagacacg cagaacaagc
      841 taaatcagaa gttgagtcag gctgaatttg aggtgcgagc cggctctatc cgtcaggaaa
      901 tcctgaacgc aaccaaggat aaagccagca agtcagaact cacgcagaca gctgaggagc
      961 tctctagtaa gat
//
LOCUS       DAVBOD010000130          938 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 640-05
            SAMEA1012484-rid20186543.denovo.131, whole genome shotgun sequence.
ACCESSION   DAVBOD010000130 DAVBOD010000000
VERSION     DAVBOD010000130.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012484
            Sequence Read Archive: ERR059358
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 938)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 938)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979948.1
            Genome Coverage       :: 595x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:03:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,266
            CDSs (total)                      :: 2,219
            Genes (coding)                    :: 2,091
            CDSs (with protein)               :: 2,091
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 71 of 128
            Pseudo Genes (incomplete)         :: 50 of 128
            Pseudo Genes (internal stop)      :: 33 of 128
            Pseudo Genes (multiple problems)  :: 22 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..938
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012484-rid20186543.denovo.131"
                     /strain="NIG 640-05"
                     /db_xref="taxon:1313"
     gene            complement(444..842)
                     /locus_tag="VQ862_002182"
     CDS             complement(444..842)
                     /locus_tag="VQ862_002182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000428147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET3116451.1"
                     /translation="MENKESHKSQEIGNLIRVYNRSKREEAESEPLNLYVEDEKGNLL
                     AGLIAETFGNWLEIEYLFVKEELRGQGIGSKLLQQAESEAKNRNCCFAFVNTYQFQAP
                     DFYQKHGYKEVFSLQDYLYIRQRYYYQKNL"
BASE COUNT          280 a          185 c          138 g          335 t
ORIGIN      
        1 tctgtgcctt tcatgtgttt gtggttgaac aacaagtata acacagaggt gttttcttat
       61 gcctacaaga gctttcatta tttccatttt cttttggatt tcactctatt ctgaaaaact
      121 tgtgtatatt tactgaagct agcaagtctt acctgtaaat ttaatgaaag caacacaaaa
      181 tccgagaggg gaatctcgga ttaatagata gagagttttt agtttaaata aattgtttaa
      241 aatatcaaca acatcacttc ttttcttaac ctgataagtc ttgattccta attttggggc
      301 tacgattata ttgtcctcaa tatcgtctag aaagacacaa tttctaggtt ataactggta
      361 tttatcgata gttactcata tacatcagtc cacctccata cttatgtgcg agcctctctt
      421 tgtattatac ctccatactc accttacaga ttcttttggt aataatatct ttgcctaatg
      481 tagagatagt cttgcaaaga aaaaacttcc ttgtagccat gtttctgata aaagtccggt
      541 gcctggaact ggtaagtatt gacaaaggca aaacaacaat ttcgattctt agcttcactt
      601 tctgcctgtt gcaatagttt tgaaccgatt ccttgccctc gcagttcctc ttttacaaac
      661 aaatactcga tttctagcca atttccaaaa gtctctgcta tcaaacctgc caggagattg
      721 cccttttcat cttcgacata aagattaagt ggctcacttt cagcctcttc tctttttgaa
      781 cggttataaa cacgaatcag attccctatt tcttgcgatt tatgtgattc cttattttcc
      841 aatctaatga aatgaaataa aacatgcgca aatcgattaa ggaatttaat ctaatttcta
      901 acaatgtctt agaaatcaaa gtgtactatt ttaacttc
//
LOCUS       DAVBOD010000131          937 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 640-05
            SAMEA1012484-rid20186543.denovo.132, whole genome shotgun sequence.
ACCESSION   DAVBOD010000131 DAVBOD010000000
VERSION     DAVBOD010000131.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012484
            Sequence Read Archive: ERR059358
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 937)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 937)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979948.1
            Genome Coverage       :: 595x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:03:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,266
            CDSs (total)                      :: 2,219
            Genes (coding)                    :: 2,091
            CDSs (with protein)               :: 2,091
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 71 of 128
            Pseudo Genes (incomplete)         :: 50 of 128
            Pseudo Genes (internal stop)      :: 33 of 128
            Pseudo Genes (multiple problems)  :: 22 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..937
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012484-rid20186543.denovo.132"
                     /strain="NIG 640-05"
                     /db_xref="taxon:1313"
     gene            complement(74..147)
                     /locus_tag="VQ862_002183"
     tRNA            complement(74..147)
                     /locus_tag="VQ862_002183"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(111..113),aa:Arg,seq:acg)
     gene            complement(157..242)
                     /locus_tag="VQ862_002184"
     tRNA            complement(157..242)
                     /locus_tag="VQ862_002184"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(206..208),aa:Leu,seq:taa)
     gene            complement(250..321)
                     /locus_tag="VQ862_002185"
     tRNA            complement(250..321)
                     /locus_tag="VQ862_002185"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(287..289),aa:Gly,seq:gcc)
     gene            complement(344..416)
                     /locus_tag="VQ862_002186"
     tRNA            complement(344..416)
                     /locus_tag="VQ862_002186"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(381..383),aa:Thr,seq:tgt)
     gene            complement(435..516)
                     /locus_tag="VQ862_002187"
     tRNA            complement(435..516)
                     /locus_tag="VQ862_002187"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(480..482),aa:Leu,seq:tag)
     gene            complement(522..594)
                     /locus_tag="VQ862_002188"
     tRNA            complement(522..594)
                     /locus_tag="VQ862_002188"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(559..561),aa:Lys,seq:ttt)
     gene            complement(619..691)
                     /locus_tag="VQ862_002189"
     tRNA            complement(619..691)
                     /locus_tag="VQ862_002189"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(656..658),aa:Asp,seq:gtc)
     gene            complement(694..766)
                     /locus_tag="VQ862_002190"
     tRNA            complement(694..766)
                     /locus_tag="VQ862_002190"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(731..733),aa:Val,seq:tac)
     gene            complement(771..886)
                     /gene="rrf"
                     /locus_tag="VQ862_002191"
     rRNA            complement(771..886)
                     /gene="rrf"
                     /locus_tag="VQ862_002191"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
BASE COUNT          242 a          270 c          199 g          226 t
ORIGIN      
        1 cgaacctgcg acaccttggt cccaaaccaa gtactctacc aagctgagct acttcccgag
       61 ttaaatagaa aaatgcaccc tagaggagtc gaacctctaa ccgcctgatt cgtagtcagg
      121 tactctatcc agttgagcta agggtgctcc atattatgcc gaggaccgga atcgaaccgg
      181 tacgatcgtt accaatcgca ggattttaag tcctgtgcgt ctgccagttc cgccaccccg
      241 gcctctctaa gcgaacgacg ggattcgaac ccgcgacccc caccttggca aggtggtgtt
      301 ctaccactga actacgttcg cactgttttc ttctatctaa aaatgccggc tacatgactt
      361 gaacacgcga ccctctgatt acaaatcaga tgctctacca actgagctaa gccggctcat
      421 ttgttatatc ttaatgcggg ttaagggact tgaaccccca cgccgttaag cgccagatcc
      481 taaatctggt gcgtctgcca attccgccaa acccgcatat atgacccgta ctgggctcga
      541 accagtgacc cattgattaa aagtcaattg ctctaccaac tgagctaacg agtctaaaat
      601 aacttgcgtt atcttaaacg gtcccgacgg gaatcgaacc cgcgatcttc gccgtgacag
      661 ggcgacgtga taaccgctac actacgggac ctttgggagt taacgggatc gaaccgctga
      721 ccctctgctt gtaaggcaga tgctctccca gctgagctaa actccctaaa gctaagcgac
      781 ttccctatct cacagggggc aacccccaac tacttccggc gttctagggc ttaacttctg
      841 tgttcggcat gggtacaggt gtatctccta ggctatcgtc acttaactct gagtaatacc
      901 tactcaaaat tgaatatcta ttcaatttaa gaaaacc
//
LOCUS       DAVBOD010000132          921 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 640-05
            SAMEA1012484-rid20186543.denovo.133, whole genome shotgun sequence.
ACCESSION   DAVBOD010000132 DAVBOD010000000
VERSION     DAVBOD010000132.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012484
            Sequence Read Archive: ERR059358
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 921)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 921)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979948.1
            Genome Coverage       :: 595x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:03:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,266
            CDSs (total)                      :: 2,219
            Genes (coding)                    :: 2,091
            CDSs (with protein)               :: 2,091
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 71 of 128
            Pseudo Genes (incomplete)         :: 50 of 128
            Pseudo Genes (internal stop)      :: 33 of 128
            Pseudo Genes (multiple problems)  :: 22 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..921
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012484-rid20186543.denovo.133"
                     /strain="NIG 640-05"
                     /db_xref="taxon:1313"
     gene            complement(<1..630)
                     /locus_tag="VQ862_002192"
     CDS             complement(<1..630)
                     /locus_tag="VQ862_002192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
                     /protein_id="HET3116452.1"
                     /translation="MDIDTSRLRTGLPQVGVQPYRQVHAHSTGNRNSTVQNEADYHWR
                     KDPELGFFSHVVGNGRIMQVGPVNNGSWDVGGGWNAESYAAVELIESHSTKEEFMTDY
                     RLYIELLRNLADEAGLPKTLDTADLAGIKTHEYCTNNQPNNHSDHVDPYPYLASWGIS
                     REQFKQDIENGLSAATGWQKNSTGYWYVHSDGSYPKDKFEKINGTWYYFD"
     gene            complement(630..>921)
                     /locus_tag="VQ862_002193"
     CDS             complement(630..>921)
                     /locus_tag="VQ862_002193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001186237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="phage holin"
                     /protein_id="HET3116453.1"
                     /translation="LVILAGVVVRAVKDYLVQKGGEKTIKIVEILAKNAVNAVEQVAA
                     ETGYKGDEKLAQARAKVRAELTKYNISMTDKDLDTFVESAVKQMNDAWKGQE"
BASE COUNT          197 a          239 c          198 g          287 t
ORIGIN      
        1 gtcaaagtag taccaagtgc cattgatttt ctcaaacttg tcttttggat aagagccgtc
       61 tgagtgtacg taccagtagc cagtgctatt tttctgccag cctgttgcag cgctcaagcc
      121 gttttcgatg tcttgcttaa actgttcacg gctaatgccc caacttgcaa gatatggata
      181 tggatccaca tggtctgagt ggttgtttgg ttggttattg gtacagtatt catgcgtctt
      241 gatacctgcc aagtcggctg tatcaagagt cttcggcaag cctgcttcgt ccgctagatt
      301 gcgtagcaat tcgatataga ggcggtagtc cgtcatgaac tcttctttag ttgaatggct
      361 ttcaatcagt tcaaccgctg cgtaactctc agcattccaa ccgcccccaa catcccaact
      421 tccgttgttc acaggtccta cctgcatgat gcgaccgttc ccaacaacgt gcgagaaaaa
      481 acctaattct gggtctttcc gccagtgata atccgcttca ttctgtacgg ttgagttacg
      541 gttgcctgtt gaatgggcgt gtacttgtcg ataaggttgc accccaacct ggggcaagcc
      601 tgtacgtagt ctgcttgtat cgatatccat tactcttgtc ctttccaagc gtcgttcatc
      661 tgcttcacgg ctgactccac aaaggtgtct aagtccttgt ccgtcatact gatattgtat
      721 tttgtaagct cagcacggac tttagcacga gcctgtgcca gtttttcatc tcccttgtag
      781 ccagtttcag cagctacctg ctccacggca tttactgcat ttttggccaa gatttcaacg
      841 attttgatgg tcttttctcc acctttttga accaggtagt ccttgactgc cctaactaca
      901 acccctgcca aaatgactag g
//
LOCUS       DAVBOD010000133          901 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 640-05
            SAMEA1012484-rid20186543.denovo.134, whole genome shotgun sequence.
ACCESSION   DAVBOD010000133 DAVBOD010000000
VERSION     DAVBOD010000133.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012484
            Sequence Read Archive: ERR059358
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 901)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 901)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979948.1
            Genome Coverage       :: 595x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:03:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,266
            CDSs (total)                      :: 2,219
            Genes (coding)                    :: 2,091
            CDSs (with protein)               :: 2,091
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 71 of 128
            Pseudo Genes (incomplete)         :: 50 of 128
            Pseudo Genes (internal stop)      :: 33 of 128
            Pseudo Genes (multiple problems)  :: 22 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..901
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012484-rid20186543.denovo.134"
                     /strain="NIG 640-05"
                     /db_xref="taxon:1313"
     gene            <1..>901
                     /locus_tag="VQ862_002194"
     CDS             <1..>901
                     /locus_tag="VQ862_002194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000339678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase S74"
                     /protein_id="HET3116454.1"
                     /translation="LELMDGMFKLNREYVTDLHFPAEVREVIQEICLKTGIELANDYF
                     GISAMRYHIEQVPEGKKLSFRDMLSAMTQMIGMSCFFNREGKMEIRDLTESNITINAD
                     SYFLHGLTKSEIEYQIAGITCKTDKKSLTVGMKTGRSLELDNVFMTQSALNDLYYKLK
                     NLTYYPYNLNYQGHLLLEVGQWVTIQTNKKETFKVPVLSQSFTFKGGLRGRISADSKA
                     GNDTQYSYEGTITKHIKQQGGIEAKIQAQIEATDKDFDQKVDKIKKDFNDQVELAKAR
                     AEEVKRELSDTINQRFNSFDNGPL"
BASE COUNT          286 a          169 c          218 g          228 t
ORIGIN      
        1 cttgaactta tggacggtat gtttaagctc aatcgtgagt acgtgacgga tttgcatttc
       61 ccagctgaag tacgagaggt tattcaggaa atctgcctga aaacaggcat tgagttagcg
      121 aatgactatt tcggaatcag cgcgatgcgt tatcatattg agcaagttcc tgagggcaag
      181 aaactttcct ttagggatat gctgagcgct atgactcaga tgattgggat gtcttgtttc
      241 ttcaacagag aaggcaagat ggaaatccgt gatttgactg agtccaatat cacgatcaac
      301 gctgacagtt acttcttgca tggcttgacc aagagtgaga ttgagtatca gatagctggt
      361 atcacttgta agacggacaa gaagtctctg acggtcggta tgaagacggg ccggtctttg
      421 gaactggaca atgtcttcat gacccagagc gctttaaatg acctgtatta caaactgaaa
      481 aacctaactt actatccgta taatctcaac taccaagggc atttactgct tgaggtcggg
      541 cagtgggtaa ccattcagac caataagaaa gagaccttta aagttcctgt gttaagtcag
      601 agctttactt ttaaaggtgg tctgagaggg cgtatcagcg cagatagtaa ggctggaaac
      661 gatactcagt attcttacga gggtacgatt accaagcata ttaagcaaca aggtggcatt
      721 gaagcgaaaa tccaagcgca gattgaagca acagataaag attttgacca aaaggtcgac
      781 aaaatcaaaa aagactttaa cgatcaagta gaactggcca aagccagagc tgaagaagtc
      841 aagagagaac tgtctgacac tatcaatcag cgatttaata gctttgacaa cgggccattg
      901 a
//
LOCUS       DAVBOD010000134          880 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 640-05
            SAMEA1012484-rid20186543.denovo.135, whole genome shotgun sequence.
ACCESSION   DAVBOD010000134 DAVBOD010000000
VERSION     DAVBOD010000134.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012484
            Sequence Read Archive: ERR059358
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 880)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 880)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979948.1
            Genome Coverage       :: 595x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:03:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,266
            CDSs (total)                      :: 2,219
            Genes (coding)                    :: 2,091
            CDSs (with protein)               :: 2,091
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 71 of 128
            Pseudo Genes (incomplete)         :: 50 of 128
            Pseudo Genes (internal stop)      :: 33 of 128
            Pseudo Genes (multiple problems)  :: 22 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..880
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012484-rid20186543.denovo.135"
                     /strain="NIG 640-05"
                     /db_xref="taxon:1313"
     gene            <1..256
                     /locus_tag="VQ862_002195"
     CDS             <1..256
                     /locus_tag="VQ862_002195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000478007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3116455.1"
                     /translation="QERKEKIIDSYRLSQMISNHVSLLLSNDAKIVEFWEYAPELFVE
                     EQQAVELERQKQALLLHKERMREFAERHNRKRKEEVNGNS"
     gene            243..>880
                     /locus_tag="VQ862_002196"
     CDS             243..>880
                     /locus_tag="VQ862_002196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000212172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3116456.1"
                     /translation="MATLDELKVMIDAEIAPFRKKMKEVENQVKGTSDRVKNATAKVR
                     EQSNSIGSAFGKLAKFAGFAILGKKLLDVGMYSTQTALEVSASMNQIKRQMGESSQSF
                     LKWVNDNANAMNMGVGEATNYGAVYSNLFSGFIEDTNKLSAYTAKMLQTSAVVAEGSG
                     RTITDVMERIRSGLLGNTEAIEDLGINVNVAMIKSTEAFKRFSNGQSWDQLD"
BASE COUNT          275 a          157 c          222 g          226 t
ORIGIN      
        1 ccaagagcgt aaagagaaga ttattgactc atacagactt tcgcagatga tttccaatca
       61 cgtttcttta ttactgtcca atgacgctaa gattgttgag ttctgggagt atgcgcctga
      121 gttatttgta gaagaacaac aagcggtaga actggaacga cagaaacaag cacttttgtt
      181 gcataaggaa cggatgcgtg aatttgcaga gagacataat cgaaaaagga aggaggaagt
      241 aaatggcaac tcttgatgaa ttgaaagtca tgattgacgc tgagatagcg cctttcagga
      301 aaaagatgaa agaagtcgag aatcaggtca aaggaacatc tgaccgagtg aaaaatgcta
      361 ctgccaaagt tcgtgaacag tcgaactcaa tcggtagtgc gtttggtaag ctggctaagt
      421 tcgctggttt tgcaatcctt ggtaagaaat tacttgatgt tgggatgtat tcaacgcaga
      481 cggctcttga agtatcagcg tctatgaacc aaatcaagcg acagatgggc gagagttcgc
      541 aatctttctt aaaatgggtt aacgataacg ccaacgctat gaatatgggt gtgggtgagg
      601 ctaccaacta cggtgcagtc tattcaaact tattttctgg atttatcgaa gataccaaca
      661 agctaagtgc ttatactgct aagatgttgc agacatcggc agtggttgct gaaggttcag
      721 ggcgcacgat tacagacgtt atggagcgga ttcgctcagg tctactaggg aacaccgaag
      781 caattgagga cctaggaatc aacgtcaatg tggctatgat taagtccact gaagctttta
      841 aacgtttctc aaatggtcaa agttgggacc aactcgactt
//
LOCUS       DAVBOD010000135          880 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 640-05
            SAMEA1012484-rid20186543.denovo.136, whole genome shotgun sequence.
ACCESSION   DAVBOD010000135 DAVBOD010000000
VERSION     DAVBOD010000135.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012484
            Sequence Read Archive: ERR059358
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 880)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 880)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979948.1
            Genome Coverage       :: 595x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:03:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,266
            CDSs (total)                      :: 2,219
            Genes (coding)                    :: 2,091
            CDSs (with protein)               :: 2,091
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 71 of 128
            Pseudo Genes (incomplete)         :: 50 of 128
            Pseudo Genes (internal stop)      :: 33 of 128
            Pseudo Genes (multiple problems)  :: 22 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..880
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012484-rid20186543.denovo.136"
                     /strain="NIG 640-05"
                     /db_xref="taxon:1313"
     gene            <1..256
                     /locus_tag="VQ862_002197"
     CDS             <1..256
                     /locus_tag="VQ862_002197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000478007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3116457.1"
                     /translation="QERKEKIIDSYILSRMITNHVSLLLSNDAKIVELWEYAPELFVE
                     EQQAVEQERQIQALLLHKERMRDFAERHNRKRKEEVNGNS"
     gene            243..>880
                     /locus_tag="VQ862_002198"
     CDS             243..>880
                     /locus_tag="VQ862_002198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000212172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3116458.1"
                     /translation="MATLDELKVMIDAEIAPFRKKMKEVENQVKGTSDRVKNATAKVR
                     EQSSSIGSAFGKLAKFAGFAILGKKLLDVGMYSTQTALEVSASMNQIKRQMGESSQSF
                     LKWVNDNANAMNMGVGEATNYGAVYSNLFSGFIKDTNKLSAYTAKMLQTSAVVAEGSG
                     RSITDVMERIRSGLLGNTEAIEDLGINVNVAMIKSTEAFKRFSNGQSWQQLD"
BASE COUNT          275 a          156 c          225 g          224 t
ORIGIN      
        1 ccaagagcgt aaagagaaga ttattgactc gtacatactt tcgcgaatga taactaatca
       61 tgtttcctta ttactgtcca atgacgctaa gattgttgag ctttgggaat atgcgcctga
      121 gttgtttgta gaagaacagc aagcagtaga acaggaacga cagatacaag cgcttttgtt
      181 gcataaggaa cggatgcgtg attttgcaga gagacataat cgaaaaagga aggaggaagt
      241 aaatggcaac tcttgatgaa ttgaaggtca tgattgacgc tgagatagcg cctttcagga
      301 agaagatgaa agaagtcgag aatcaggtca aaggaacatc tgaccgagtg aaaaatgcta
      361 ctgccaaagt tcgtgaacag tcgagctcaa tcggtagtgc gtttggcaag ctggctaagt
      421 tcgctggttt tgcaatcctt ggtaagaaat tacttgatgt tgggatgtat tcaacgcaga
      481 cagctcttga agtgtcagcg tctatgaacc aaattaagcg acagatgggt gagagttcgc
      541 aatctttctt aaaatgggtt aacgataacg ctaatgccat gaatatgggt gtgggcgagg
      601 ctactaacta tggtgcagtc tactcaaact tattttctgg atttatcaaa gataccaaca
      661 agctaagcgc ctataccgct aagatgttgc agacatcggc agtggttgct gaaggctcag
      721 ggcgtagcat tacagacgtt atggagcgga ttcgctcagg tttgctaggg aacaccgaag
      781 caattgagga cctaggaatc aacgtcaatg tggctatgat taagtccact gaagctttta
      841 aacgtttctc aaacggacaa agctggcaac aattagacta
//
LOCUS       DAVBOD010000136          859 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 640-05
            SAMEA1012484-rid20186543.denovo.137, whole genome shotgun sequence.
ACCESSION   DAVBOD010000136 DAVBOD010000000
VERSION     DAVBOD010000136.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012484
            Sequence Read Archive: ERR059358
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 859)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 859)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979948.1
            Genome Coverage       :: 595x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:03:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,266
            CDSs (total)                      :: 2,219
            Genes (coding)                    :: 2,091
            CDSs (with protein)               :: 2,091
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 71 of 128
            Pseudo Genes (incomplete)         :: 50 of 128
            Pseudo Genes (internal stop)      :: 33 of 128
            Pseudo Genes (multiple problems)  :: 22 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..859
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012484-rid20186543.denovo.137"
                     /strain="NIG 640-05"
                     /db_xref="taxon:1313"
     gene            complement(<1..165)
                     /locus_tag="VQ862_002199"
     CDS             complement(<1..165)
                     /locus_tag="VQ862_002199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-dehydroquinate synthase"
                     /protein_id="HET3116459.1"
                     /translation="MPTRTKRKYILVISGYAGNKQVEERFEVTANEYKHYEIGNTFIQ
                     DAVLENKEEDK"
     gene            complement(312..803)
                     /locus_tag="VQ862_002200"
     CDS             complement(312..803)
                     /locus_tag="VQ862_002200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000612396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3116460.1"
                     /translation="MIPKFRAWVKIGKRMVFSDDILAIDYENKEIVTQQVYFESGLAV
                     ERDIYCYDFDDIELMQSTGLFDRNGKEIFEGDILKFNDEWNEYCHEGYVDGSVEGVNY
                     VEVVRSEICFEFGKTKYPDSSLFILMEDEQLNFKDFIKSEDFEFEIIGNIYENPELLE
                     VNE"
BASE COUNT          253 a          202 c          115 g          289 t
ORIGIN      
        1 tttatcctcc tccttatttt ctaaaacggc atcctgtata aaagtattgc caatttcata
       61 gtgcttgtat tcatttgctg tcacttcaaa cctttcttca acttgcttat tacctgcata
      121 tcctgaaatg accagaatgt attttctttt ggttctggtt ggcacaagta ccgaactttt
      181 accatttata acaggtatga acgttgtgtg aggttcatca atgtacttat ctaccactgt
      241 cccactcgaa atctggtgac atgctacgag taaggatgcg aataaaacaa tacataggat
      301 tttaaaatat ctcactcgtt gacctctaaa agttcagggt tttcgtagat gttgccgatg
      361 atttcaaatt caaaatcttc acttttaata aaatccttga aattaagctg ctcatcttcc
      421 atgagaataa acaaagagga gtcaggatat ttagtttttc caaactcaaa acaaatttca
      481 cttctcacca cttcaacgta attaacgcct tcgactgagc cgtctacata gccctcgtgg
      541 caatattcat tccactcatc attaaatttc agtatatccc cctcaaagat ttccttacca
      601 tttctgtcaa acaatcctgt tgattgcatg agttcgatat cgtcaaaatc ataacaatag
      661 atatctcttt caactgctag accactctcg aaataaactt gttgtgtcac tatttctttg
      721 ttttcgtagt caatagcaag aatgtcatct gaaaaaacca tacgttttcc tatttttacc
      781 cacgctctaa attttggaat cattcctcca cctcctctat ctcaacacct tcacaatcga
      841 acacccatcc gaggccagc
//
LOCUS       DAVBOD010000137          821 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 640-05
            SAMEA1012484-rid20186543.denovo.138, whole genome shotgun sequence.
ACCESSION   DAVBOD010000137 DAVBOD010000000
VERSION     DAVBOD010000137.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012484
            Sequence Read Archive: ERR059358
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 821)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 821)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979948.1
            Genome Coverage       :: 595x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:03:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,266
            CDSs (total)                      :: 2,219
            Genes (coding)                    :: 2,091
            CDSs (with protein)               :: 2,091
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 71 of 128
            Pseudo Genes (incomplete)         :: 50 of 128
            Pseudo Genes (internal stop)      :: 33 of 128
            Pseudo Genes (multiple problems)  :: 22 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..821
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012484-rid20186543.denovo.138"
                     /strain="NIG 640-05"
                     /db_xref="taxon:1313"
     gene            712..821
                     /locus_tag="VQ862_002201"
                     /pseudo
     CDS             712..821
                     /locus_tag="VQ862_002201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
BASE COUNT          290 a          127 c          130 g          274 t
ORIGIN      
        1 taaaatctgg atattagggt ctttaatgtc tagtaatttt gtgataaaat gtaattgttc
       61 catatgattc tttctaatga gttgttttgt cgcttttcat tataggtcat atgggacttt
      121 ttttctacac aaaaataggc tccataatat ctatagtgga tttacccact acaaatatta
      181 tagagcccta atctggagat ttcttatttg cacttttctt gtacaacttt agtccacggt
      241 aaataggcct ctaaaacctc tttgtttacg agagtttcct cgtttggaag acattctaga
      301 agataggata gatatttctc gctatttata ctagactaaa atcaaaaagc attatataat
      361 agtgatatga aatcaactaa agaagaaatc caaaccatca aaacactttt aaaagactct
      421 cgtacagcta aatatcataa acgccttcaa atcgttctat agtaaaatga aataagaaca
      481 gtacaaatcg atcaggacag tcaaattgat ttctaacaat gttttagaag tagaggtgta
      541 ctattctagt ttcaatctat tatatttcgt ctgatgggca aatcttataa agagattata
      601 gaacttttat agtagtttga aataagatgt gaacaactct atcaggaaag tcaaattaat
      661 ttatagaaat attttagcag ccaaggtgta ctgttataga ttcaatacac tatagactgt
      721 aatcaaacaa cgatttggcg aaatgtaaaa aaatatgagg agttcggact cgactctctc
      781 cttcaagaaa cacgtggtgg tcgtaaccat gcatatatga c
//
LOCUS       DAVBOD010000138          816 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 640-05
            SAMEA1012484-rid20186543.denovo.139, whole genome shotgun sequence.
ACCESSION   DAVBOD010000138 DAVBOD010000000
VERSION     DAVBOD010000138.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012484
            Sequence Read Archive: ERR059358
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 816)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 816)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979948.1
            Genome Coverage       :: 595x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:03:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,266
            CDSs (total)                      :: 2,219
            Genes (coding)                    :: 2,091
            CDSs (with protein)               :: 2,091
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 71 of 128
            Pseudo Genes (incomplete)         :: 50 of 128
            Pseudo Genes (internal stop)      :: 33 of 128
            Pseudo Genes (multiple problems)  :: 22 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..816
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012484-rid20186543.denovo.139"
                     /strain="NIG 640-05"
                     /db_xref="taxon:1313"
     gene            <1..>816
                     /locus_tag="VQ862_002202"
     CDS             <1..>816
                     /locus_tag="VQ862_002202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000339662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase S74"
                     /protein_id="HET3116461.1"
                     /translation="LELMDGMFKLNREYVTDLHFPAEVREVIQEICLKTGIELANDYF
                     GISAMRYHIEQVPEGKKLSFRDMLSAMTQMIGMSCFFNREGKMEIRDLTESNITINAD
                     SYFLHGLTKSEIEYQISGITCKTDKKSLTVGMKTGRSLELDNVFMTQSALNDLYYKLK
                     NLTYYPYNLNYQGHLLLEVGQWVTIQTNKKETFKVPVLSQSFTFKGGLRGRISADSKA
                     GNDTQYSYEGTITKQIKQQDGVEAKIQAQIEAADKDFDQKVDKIKKDFNDQVEL"
BASE COUNT          262 a          148 c          192 g          214 t
ORIGIN      
        1 cttgaactca tggatggtat gtttaagctc aatcgtgagt atgtgacgga cttacatttt
       61 ccagctgaag tacgagaggt tattcaggaa atctgcctga aaacaggcat tgagttagcg
      121 aatgactatt tcggaatcag cgctatgcgt taccatatcg agcaagttcc tgaaggtaag
      181 aaactttcgt tcagggatat gctgagcgct atgactcaga tgattgggat gtcttgtttc
      241 ttcaacagag aaggcaagat ggaaatccgt gatttgactg agtccaatat cacgatcaac
      301 gctgacagtt acttcttgca tggcttgacc aagagtgaga ttgagtatca gatatctggt
      361 atcacttgta agacggacaa gaagtctctg acggtcggta tgaagacagg tcggtctttg
      421 gaactggaca atgtcttcat gacccagagt gctttaaatg acctgtatta caaactgaaa
      481 aacctaactt actatccgta taatctcaac taccaagggc atttactgct tgaggttggg
      541 cagtgggtaa ccattcagac caataagaaa gagactttta aagttcctgt cttaagtcag
      601 agctttactt tcaaaggtgg tctgagaggt cgtatcagcg cagatagtaa agctggaaat
      661 gatactcagt attcttacga gggaacgatt accaagcaga taaagcaaca agatggcgtt
      721 gaagcaaaaa tccaagcgca gattgaagca gcagataaag attttgacca aaaggtcgac
      781 aaaatcaaaa aagactttaa cgatcaagta gaactg
//
LOCUS       DAVBOD010000139          800 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 640-05
            SAMEA1012484-rid20186543.denovo.140, whole genome shotgun sequence.
ACCESSION   DAVBOD010000139 DAVBOD010000000
VERSION     DAVBOD010000139.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012484
            Sequence Read Archive: ERR059358
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 800)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 800)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979948.1
            Genome Coverage       :: 595x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:03:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,266
            CDSs (total)                      :: 2,219
            Genes (coding)                    :: 2,091
            CDSs (with protein)               :: 2,091
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 71 of 128
            Pseudo Genes (incomplete)         :: 50 of 128
            Pseudo Genes (internal stop)      :: 33 of 128
            Pseudo Genes (multiple problems)  :: 22 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..800
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012484-rid20186543.denovo.140"
                     /strain="NIG 640-05"
                     /db_xref="taxon:1313"
     gene            complement(<1..>800)
                     /locus_tag="VQ862_002203"
     CDS             complement(<1..>800)
                     /locus_tag="VQ862_002203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002644521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3116462.1"
                     /translation="TQTAEELASRIASVQAGSSRNYFRNSRSRTFTTGGQAVYDYRTF
                     IVPDFWKNSDRFKRDYVRISFDVTFPVALVNDMPAMVHFSAHPWYAYRNLIFKGGTVE
                     RQHFEFTIDLSSSSEDYQTNNVFIRFGTNYGFPAGLQVVIENAMLSVGNYFPAYQPAY
                     EDQEDRVSVVESNFKQRADSLDAGVRSLTEGLRTKADISSLNVTAENIRQSVKSLETD
                     TQNKLNQKLSQAEFEVRAGSIRQEILNATKDKASKSELTQTAEELASR"
BASE COUNT          215 a          194 c          167 g          224 t
ORIGIN      
        1 atccgactag ccagctcctc agctgtctgc gtgagttctg acttgctggc tttatccttg
       61 gttgcgttca ggatttcctg acggatagag ccggctcgca cctcaaattc agcctgactc
      121 aacttctgat ttagcttgtt ctgcgtatct gtctcaaggc tcttcacaga ttgccggata
      181 ttttcagcag tcacattgag tgagctgata tccgctttgg ttctaaggcc ttcagtcaag
      241 cttcttacac cagcgtcgag tgaatcagca cgctgtttaa agttggattc gactactgag
      301 acacggtctt cttggtcttc atacgctggt tgataggctg gaaaataatt accaaccgat
      361 aacatagcgt tctcaatgac gacctgcaga ccagcaggaa atccataatt agtaccaaaa
      421 cgaatgaaca cattattagt ctgatagtcc tcagaagaac tagacaagtc aatcgtaaac
      481 tcaaaatgtt ggcgttcgac agttccacct ttaaaaatta agtttctgta ggcataccat
      541 ggatgagcac taaaatgcac catagcaggc atgtcattta ctagggcgac agggaaagtc
      601 acatcaaaag atatgcgaac ataatcacgc ttgaacctgt cactgttctt ccagaaatca
      661 ggaactatga atgttcgata gtcgtatacc gcttgacctc ctgttgtgaa cgttcttgaa
      721 cgtgaattcc tgaagtaatt ccgtgaacta cctgcctgca cactcgcaat ccgactagcc
      781 agctcctcag ctgtttgcgt
//
LOCUS       DAVBOD010000140          777 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 640-05
            SAMEA1012484-rid20186543.denovo.141, whole genome shotgun sequence.
ACCESSION   DAVBOD010000140 DAVBOD010000000
VERSION     DAVBOD010000140.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012484
            Sequence Read Archive: ERR059358
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 777)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 777)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979948.1
            Genome Coverage       :: 595x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:03:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,266
            CDSs (total)                      :: 2,219
            Genes (coding)                    :: 2,091
            CDSs (with protein)               :: 2,091
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 71 of 128
            Pseudo Genes (incomplete)         :: 50 of 128
            Pseudo Genes (internal stop)      :: 33 of 128
            Pseudo Genes (multiple problems)  :: 22 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..777
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012484-rid20186543.denovo.141"
                     /strain="NIG 640-05"
                     /db_xref="taxon:1313"
     gene            complement(<1..>777)
                     /locus_tag="VQ862_002204"
     CDS             complement(<1..>777)
                     /locus_tag="VQ862_002204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001840641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tail fiber domain-containing protein"
                     /protein_id="HET3116463.1"
                     /translation="TQTKMTQLAGSWVVENINSAGDIISGINLGANGHNRLVGKLTHI
                     TGETLIDRAVIKSAMVDKLKTANFEAGSVTTTILEAEAVTAEKLKVDDALIRKLTAKD
                     AFIDRLTSKRIFSTKVESVISSSTFLEAYQGRIGGFTLGQFDQGGGRWISGVNQFSVG
                     MGNGAGYGVRTAFWANWGNNWNYAGPKAWNVNTDGKMYCRNEVGFYDQVDFSNSSRAN
                     FYGNTTFSRSPVFSNGIELGSKDVLGDGWNPKGGRNAVVWW"
BASE COUNT          214 a          201 c          147 g          215 t
ORIGIN      
        1 ccaccaaaca accgcattcc ttccgccttt gggattccaa ccatcaccaa gcacatcttt
       61 acttccaagt tcgataccat ttgaaaacac aggagaacga gaaaaagtag tattcccata
      121 gaagtttgct ctcgatgaat tcgaaaaatc cacttgatca taaaaaccga cttcattcct
      181 acagtacatt ttcccatcag tattgacgtt ccatgcttta ggtccggcat agttccaatt
      241 atttccccag ttcgcccaga aggctgtccg gactccatac ccggcaccat tccccatacc
      301 aacagagaac tgattgacac ctgaaatcca gcgaccgcca ccctggtcaa attgaccaag
      361 tgtgaatcca ccgattcggc cttgataggc ttctaggaag gttgagctag aaatgacgga
      421 ctcaacctta gtagagaaga tacgtttaga tgtcagtcgg tcaataaaag catcttttgc
      481 agttaatttt ctaataagcg catcgtcaac tttcaacttc tcagcagtta ccgcttcagc
      541 ttctaatatc gtagtcgtga ccgaaccagc ttcaaaattg gccgttttga gcttatcaac
      601 catggcagac ttgatgactg ctctgtcaat cagggtctct ccagtgatgt gggtcaattt
      661 cccaactaag cggttatgtc cattggcgcc aagattgatt ccagagatga tatctccagc
      721 cgagttgatg ttttcaacta cccatgagcc agctagttga gtcatttttg tttgcgt
//
LOCUS       DAVBOD010000141          776 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 640-05
            SAMEA1012484-rid20186543.denovo.142, whole genome shotgun sequence.
ACCESSION   DAVBOD010000141 DAVBOD010000000
VERSION     DAVBOD010000141.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012484
            Sequence Read Archive: ERR059358
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 776)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 776)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979948.1
            Genome Coverage       :: 595x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:03:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,266
            CDSs (total)                      :: 2,219
            Genes (coding)                    :: 2,091
            CDSs (with protein)               :: 2,091
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 71 of 128
            Pseudo Genes (incomplete)         :: 50 of 128
            Pseudo Genes (internal stop)      :: 33 of 128
            Pseudo Genes (multiple problems)  :: 22 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..776
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012484-rid20186543.denovo.142"
                     /strain="NIG 640-05"
                     /db_xref="taxon:1313"
     gene            <1..120
                     /locus_tag="VQ862_002205"
     CDS             <1..120
                     /locus_tag="VQ862_002205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001186237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin"
                     /protein_id="HET3116464.1"
                     /translation="RAKIRAELTKYNISMTDKDLDTFVESAVKQMNDAWKGQE"
     gene            120..>776
                     /locus_tag="VQ862_002206"
     CDS             120..>776
                     /locus_tag="VQ862_002206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
                     /protein_id="HET3116465.1"
                     /translation="MDIDRNRLRTGLPQVGVQPYRQVHAHSTGNRNSTAQNEADYHYR
                     KDPELGFFSHVVGNGRIMQVGPVNNGSWDVGGGWNAESYAAVELIESHSTKEEFMADY
                     RLYIELLRNLADEAGLPKTLDTGSLAGIKTHEYCTNNQPNNHSDHVDPYPYLASWGIS
                     REQFKQDIENGLSAATGWQKNGTGYWYVHSDGSYPKDKFEKINGTWYYFDGSGYMLSD
                     R"
BASE COUNT          236 a          168 c          197 g          175 t
ORIGIN      
        1 cgcgctaaaa ttcgtgcaga gctgaccaaa tataatatca gtatgacgga caaggacttg
       61 gacacctttg tggagtcagc cgtgaagcag atgaacgacg cttggaaagg acaagagtaa
      121 tggatatcga tagaaacaga ctacgtacag gcttgcccca ggttggggtg cagccttatc
      181 gacaagtaca tgctcactca acaggcaacc gtaactcaac cgctcaaaat gaagctgatt
      241 accactatag aaaggaccct gaactagggt tcttttcaca tgttgtcgga aacggccgca
      301 tcatgcaggt aggacctgtg aacaacggaa gttgggatgt tgggggcggt tggaatgctg
      361 agagttatgc agcggttgaa ctgattgaaa gccattcaac taaggaagag tttatggctg
      421 actatcgcct ctatatcgaa ttgctacgca atctagcaga tgaagcaggt ttgccgaaaa
      481 cgcttgatac agggagttta gctggaatta aaacgcacga gtattgcacg aataaccaac
      541 caaacaacca ctcagaccac gttgaccctt atccatatct tgcaagttgg ggcattagcc
      601 gtgagcagtt taagcaagac atcgaaaacg gcttgagcgc tgcgacaggc tggcagaaaa
      661 atggtactgg ctactggtac gtacactcag acggctctta tccaaaagac aagtttgaga
      721 aaatcaacgg tacctggtat tatttcgatg gctcaggcta tatgctttca gaccgc
//
LOCUS       DAVBOD010000142          758 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 640-05
            SAMEA1012484-rid20186543.denovo.143, whole genome shotgun sequence.
ACCESSION   DAVBOD010000142 DAVBOD010000000
VERSION     DAVBOD010000142.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012484
            Sequence Read Archive: ERR059358
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 758)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 758)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979948.1
            Genome Coverage       :: 595x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:03:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,266
            CDSs (total)                      :: 2,219
            Genes (coding)                    :: 2,091
            CDSs (with protein)               :: 2,091
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 71 of 128
            Pseudo Genes (incomplete)         :: 50 of 128
            Pseudo Genes (internal stop)      :: 33 of 128
            Pseudo Genes (multiple problems)  :: 22 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..758
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012484-rid20186543.denovo.143"
                     /strain="NIG 640-05"
                     /db_xref="taxon:1313"
     gene            <1..>758
                     /locus_tag="VQ862_002207"
     CDS             <1..>758
                     /locus_tag="VQ862_002207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000187281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HET3116466.1"
                     /translation="DGSTQEIDVPYDIPDTWEWVRIKSIYWNFGQNKPEKSFRYIDTS
                     SIDRKKNIINYKNLQYLSPEQAPSRARKLVSQNSVLFSTVRPYLKNIAVVRELKEYLI
                     ASTAFIVLDTLLNETYLKYYLLSDNFINRVNNKSTGTSYPAINDYNFNLLLIALPPLS
                     EQQRIVEAIESALEKVDEYAESYNRLEQLDKEFPDKLKKSILQYAMQGKLVEQDPNDE
                     SVEVLLEKIRAEKQKLFEEGKIKKKDLDISIVSQ"
BASE COUNT          297 a          110 c          120 g          231 t
ORIGIN      
        1 tgatggaagt actcaagaaa ttgatgttcc ttatgatatt cctgatactt gggagtgggt
       61 gaggataaaa tcaatttatt ggaattttgg gcaaaataag ccagagaaat cctttaggta
      121 tatagatacg tctagtattg atagaaaaaa gaacataatc aactacaaaa atctacaata
      181 tctttcacct gaacaagcgc cttcccgtgc cagaaaatta gtttcgcaga atagtgtctt
      241 attttcaaca gttagaccat atctaaaaaa tattgctgta gttagagaac ttaaagagta
      301 tttgatagct agtacagcat ttattgtttt ggatacttta cttaacgaaa catatttgaa
      361 atattattta ttatcagata attttatcaa tcgtgttaat aataaatcta ctggaacaag
      421 ttatcctgca atcaatgatt ataattttaa tctattatta attgctctcc ccccactatc
      481 cgaacaacaa cgaatagtag aagcaatcga atcagcttta gaaaaagtag atgaatatgc
      541 tgaaagttat aatagactag aacagctaga taaagaattt ccagataaac taaaaaaatc
      601 tattcttcaa tatgctatgc aaggaaaatt agttgaacaa gacccaaatg atgaatcagt
      661 cgaagtttta cttgaaaaaa tacgagcaga aaaacaaaaa ctctttgaag aaggcaagat
      721 taaaaagaaa gatttggaca tttctattgt ttcccaag
//
LOCUS       DAVBOD010000143          754 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 640-05
            SAMEA1012484-rid20186543.denovo.144, whole genome shotgun sequence.
ACCESSION   DAVBOD010000143 DAVBOD010000000
VERSION     DAVBOD010000143.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012484
            Sequence Read Archive: ERR059358
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 754)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 754)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979948.1
            Genome Coverage       :: 595x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:03:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,266
            CDSs (total)                      :: 2,219
            Genes (coding)                    :: 2,091
            CDSs (with protein)               :: 2,091
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 71 of 128
            Pseudo Genes (incomplete)         :: 50 of 128
            Pseudo Genes (internal stop)      :: 33 of 128
            Pseudo Genes (multiple problems)  :: 22 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..754
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012484-rid20186543.denovo.144"
                     /strain="NIG 640-05"
                     /db_xref="taxon:1313"
     gene            252..592
                     /gene="tnpB"
                     /locus_tag="VQ862_002208"
                     /pseudo
     CDS             252..592
                     /gene="tnpB"
                     /locus_tag="VQ862_002208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001849103.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
     gene            complement(625..754)
                     /locus_tag="VQ862_002209"
                     /pseudo
     CDS             complement(625..754)
                     /locus_tag="VQ862_002209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="internal stop; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="IS630 family transposase"
BASE COUNT          231 a          148 c          133 g          242 t
ORIGIN      
        1 tcaatttcat aataaaaaca ccccaaaagt tagatttttt ctgtctaact tttggggggc
       61 agttcattct acacccacta ttatgcgttt ttatcatttt gaaatctact gctaatcaat
      121 gaagaagcaa agatcaaact aggcagctag ttacaagtta cgtaagcgcg tcataacaag
      181 gtatctatcc taattcccca acttccagta tactagataa aaaataatta tcggaggaaa
      241 ggtattgtac tatgataatt caactaagtg atttaggtca agttcacctt gtttgtagca
      301 agatagatat gaggcaggga atagactcat tagcctatgt agttaaaacc cactttgaat
      361 tggatccttt ctccggtcaa gtctttctct tttgtggtgg acgtaaagac cgctttaaag
      421 ccctttactg ggatggtcaa ggattttggc tactatataa acgctttgag aacggcagac
      481 tgacttggcc cagtacagaa aaggatgtca aagctctcac acctgaacaa gtagactggc
      541 ttatgaaggg cttttctatc actccaaaaa taaatccatc agaaagtcgt gatttctatt
      601 gaaatgagga ctttcttttt atactcatct gctttcaaaa agcattctag tccatctccg
      661 attaacgatg ggctttatca cctccttctc cagtccttgt atgatatctt aaagttgatt
      721 catgacatct tccaaagttt gaaaggcttt attt
//
LOCUS       DAVBOD010000144          700 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 640-05
            SAMEA1012484-rid20186543.denovo.145, whole genome shotgun sequence.
ACCESSION   DAVBOD010000144 DAVBOD010000000
VERSION     DAVBOD010000144.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012484
            Sequence Read Archive: ERR059358
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 700)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 700)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979948.1
            Genome Coverage       :: 595x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:03:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,266
            CDSs (total)                      :: 2,219
            Genes (coding)                    :: 2,091
            CDSs (with protein)               :: 2,091
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 71 of 128
            Pseudo Genes (incomplete)         :: 50 of 128
            Pseudo Genes (internal stop)      :: 33 of 128
            Pseudo Genes (multiple problems)  :: 22 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..700
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012484-rid20186543.denovo.145"
                     /strain="NIG 640-05"
                     /db_xref="taxon:1313"
     gene            3..305
                     /locus_tag="VQ862_002210"
     CDS             3..305
                     /locus_tag="VQ862_002210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000590570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HET3116467.1"
                     /translation="MIKILAACGAGVNSSHQIKSALEEELSNRGYDVHCDAVMVKDVN
                     EDLMKGYDIFTPIAATDLGFEPGIPVIEAGPILFCIPAMSVPVFDNIRLPAKQNMV"
     gene            313..>700
                     /locus_tag="VQ862_002211"
     CDS             313..>700
                     /locus_tag="VQ862_002211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS5 family transposase"
                     /protein_id="HET3116468.1"
                     /translation="MNYEASKQLTDARFKRLVGVQRTTFEEILAVLKTAYQLKHAKGG
                     RKPKLSLEDFLMATLQYVREYRTYEEIAADFGIHESNLIRRSRWVEVTLVQSGVTISR
                     TPLSSEDTVMIDATEVQINRPKKTISE"
BASE COUNT          230 a          131 c          144 g          195 t
ORIGIN      
        1 aaatgattaa aattcttgct gcctgcggtg caggtgttaa ctcaagtcac caaattaaaa
       61 gtgctctaga agaagaactt tcaaaccgtg gttatgatgt tcactgtgat gcagttatgg
      121 tgaaagatgt aaacgaagac cttatgaaag gttacgatat ctttacacca atcgctgcaa
      181 cagaccttgg ttttgaacca ggtatcccag ttatcgaagc tgggccaatc ttattctgta
      241 tcccagcaat gagcgttcca gtatttgaca atattagact tcctgcgaaa caaaatatgg
      301 tatagtagtt ccatgaatta tgaagcaagt aaacaactaa ctgatgcacg atttaagcgt
      361 cttgttggtg ttcaacgcac gacttttgaa gagatattag ctgtattaaa aacagcttat
      421 caacttaaac acgcaaaagg tggacgaaaa cctaaattaa gcctagaaga ctttcttatg
      481 gccactcttc aatatgtgcg agaatatcga acttatgaag aaattgcggc tgattttggt
      541 atccacgaaa gcaacttaat ccgtcggagc cgatgggttg aagtaactct tgttcaaagt
      601 ggtgttacga tttcaagaac tcctctcagt tctgaggaca cggtaatgat tgatgcgacg
      661 gaagtacaaa tcaatcgccc taaaaaaaca attagcgaat
//
LOCUS       DAVBOD010000145          691 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 640-05
            SAMEA1012484-rid20186543.denovo.146, whole genome shotgun sequence.
ACCESSION   DAVBOD010000145 DAVBOD010000000
VERSION     DAVBOD010000145.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012484
            Sequence Read Archive: ERR059358
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 691)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 691)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979948.1
            Genome Coverage       :: 595x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:03:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,266
            CDSs (total)                      :: 2,219
            Genes (coding)                    :: 2,091
            CDSs (with protein)               :: 2,091
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 71 of 128
            Pseudo Genes (incomplete)         :: 50 of 128
            Pseudo Genes (internal stop)      :: 33 of 128
            Pseudo Genes (multiple problems)  :: 22 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..691
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012484-rid20186543.denovo.146"
                     /strain="NIG 640-05"
                     /db_xref="taxon:1313"
     gene            13..280
                     /locus_tag="VQ862_002212"
                     /pseudo
     CDS             13..280
                     /locus_tag="VQ862_002212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001823653.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            290..>691
                     /locus_tag="VQ862_002213"
     CDS             290..>691
                     /locus_tag="VQ862_002213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003038967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin family protein"
                     /protein_id="HET3116469.1"
                     /translation="MQIEFFNFLRSVVQTEDGLVLYALALIVSMEIIDFVTGTIAAII
                     NPDIEYKSKIGINGLLRKISGVLLLMILIPASVLLPEKTGFVFLHSIYLGYIAFTFQS
                     LIENYRKLKGNVTLFQPIVKVFQRLLEKDDDT"
BASE COUNT          199 a          125 c          158 g          209 t
ORIGIN      
        1 gctttgcgct acatgaaaga aaatggagag ttcattcgtt gcaagaatgt aagcgatgac
       61 ttctatatgt atcgtgatgt tcaaaaacgt cctgtgatcg taaatggccg tcgccaattc
      121 aaggatgttg aaactgtttg ggcgttcaac cagtgggggg ggggggacaa tcacaacaat
      181 caacgtagcc gttctgttga atcatgaatt ctatatcatg aaatttgatg cagagggcaa
      241 tcctgactgg acggatccaa cggtaaaacc taaagaatag gaggtgtgta tgcaaattga
      301 atttttcaat tttctaagaa gtgtcgtaca gactgaagat ggtttggtct tgtacgctct
      361 agcactgatt gtctcaatgg aaatcattga ttttgtgaca gggacgattg cggcgattat
      421 caatcctgac atcgagtaca agagcaaaat cggcattaac gggctccttc gtaagatttc
      481 aggggttctc ttactgatga tcctcattcc ggcgtccgtt ttgttgcctg aaaagacagg
      541 ttttgtattc ttgcactcaa tctatctcgg gtacatcgca tttacttttc aatctctcat
      601 tgaaaattac cgcaaattaa aaggaaatgt tactcttttt cagccgattg taaaagtatt
      661 tcagcgatta cttgaaaaag atgatgatac g
//
LOCUS       DAVBOD010000146          688 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 640-05
            SAMEA1012484-rid20186543.denovo.147, whole genome shotgun sequence.
ACCESSION   DAVBOD010000146 DAVBOD010000000
VERSION     DAVBOD010000146.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012484
            Sequence Read Archive: ERR059358
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 688)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 688)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979948.1
            Genome Coverage       :: 595x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:03:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,266
            CDSs (total)                      :: 2,219
            Genes (coding)                    :: 2,091
            CDSs (with protein)               :: 2,091
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 71 of 128
            Pseudo Genes (incomplete)         :: 50 of 128
            Pseudo Genes (internal stop)      :: 33 of 128
            Pseudo Genes (multiple problems)  :: 22 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..688
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012484-rid20186543.denovo.147"
                     /strain="NIG 640-05"
                     /db_xref="taxon:1313"
     gene            484..>688
                     /locus_tag="VQ862_002214"
     CDS             484..>688
                     /locus_tag="VQ862_002214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001852057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3116470.1"
                     /translation="MFDNVGNLSEAVGNIAQDFSSAFYDVITSTGAVRIGSAIVSTLL
                     SLTSTIVEVGSKLAGSLFKGFEKV"
BASE COUNT          199 a          121 c          182 g          186 t
ORIGIN      
        1 ttgggatttg atgagattaa catcttgcaa aaaccaaaag atgacgacgc aggcggttct
       61 ggaggcggtg gcaaaggtgg taaaggaaag ggaggcggtg gcggaccttt caaagacatc
      121 ttgccagaag tcgagttgac cgacatggac aacaaattca agagcatttt tgatggtctt
      181 ggagataagc tcaaagggtt gtttgacctc ttcaagaaag gttttgatgc agcatttaga
      241 ccagaaggta taaaacgcat taagactgcc ttagaccaaa tagctaagac aatgggagaa
      301 atcgccactg acccaagggt tgtgaatgcc tttaaccgaa tggctgagaa aattgcttat
      361 gctttagggc aagtgacagg ctcaataacc actatcgggc taggtatcgg tgttttcctt
      421 gccgaaagta ttgcaaatgg ccttggaagg caaaaagaac gcattatcag ggcgctagtc
      481 gctttgtttg ataatgttgg taacctttcc gaggcagtag gaaacatagc tcaggacttt
      541 tctagtgctt tctacgacgt cattacctca actggtgcgg ttcgtatcgg tagcgctatt
      601 gtgtcaactc tgttgagttt gacatctacc attgttgaag ttggtagtaa attagcagga
      661 agtttgttta aaggttttga aaaagtcg
//
LOCUS       DAVBOD010000147          649 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 640-05
            SAMEA1012484-rid20186543.denovo.148, whole genome shotgun sequence.
ACCESSION   DAVBOD010000147 DAVBOD010000000
VERSION     DAVBOD010000147.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012484
            Sequence Read Archive: ERR059358
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 649)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 649)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979948.1
            Genome Coverage       :: 595x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:03:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,266
            CDSs (total)                      :: 2,219
            Genes (coding)                    :: 2,091
            CDSs (with protein)               :: 2,091
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 71 of 128
            Pseudo Genes (incomplete)         :: 50 of 128
            Pseudo Genes (internal stop)      :: 33 of 128
            Pseudo Genes (multiple problems)  :: 22 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..649
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012484-rid20186543.denovo.148"
                     /strain="NIG 640-05"
                     /db_xref="taxon:1313"
     gene            1..649
                     /locus_tag="VQ862_002215"
                     /pseudo
     CDS             1..649
                     /locus_tag="VQ862_002215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="frameshifted; internal stop; incomplete; missing
                     N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="IS3 family transposase"
BASE COUNT          253 a          101 c          131 g          164 t
ORIGIN      
        1 aaataaattt gggataaaca attctaatct taggtacatg attaaattga ttgatcgtta
       61 cggaatagag ttcgtcaaaa aaggaaaaaa tcgttactat tctcctgatt taaaacaaga
      121 aatgattcat aaagtctgac atgaaggcta gactaaagat agagtttctc ttgaatacgg
      181 tctcccaagt cgtacgatac ttcttaactg gctagcacaa tacaggaaaa acgggtatac
      241 tattgttgag aaaccaagag ggagagtacc taaaatggga cgtaagccaa gaacgagacc
      301 tgaagagagg acagaattag aacgtcttca agcagaaaat gagtacctga gagcggagaa
      361 tgccatccta aaaaagttaa gagaactccg attgaaggag gaaaaagaga aagaagaaag
      421 atagaaattg ttcaagaatt aatgactgag ttttcgttag atcttcttct aaaagccatt
      481 aaactagctc gttggaccta ctactatcac ttgaaacagt tagacaaacc agataaggac
      541 caagagctta aagctgaaat tcaattcatt tttatcgaac acaagggaaa ttatacttat
      601 cgccgggttc atttagaact aagaaatcgt ggttatctgg taaatcata
//
LOCUS       DAVBOD010000148          645 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 640-05
            SAMEA1012484-rid20186543.denovo.149, whole genome shotgun sequence.
ACCESSION   DAVBOD010000148 DAVBOD010000000
VERSION     DAVBOD010000148.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012484
            Sequence Read Archive: ERR059358
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 645)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 645)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979948.1
            Genome Coverage       :: 595x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:03:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,266
            CDSs (total)                      :: 2,219
            Genes (coding)                    :: 2,091
            CDSs (with protein)               :: 2,091
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 71 of 128
            Pseudo Genes (incomplete)         :: 50 of 128
            Pseudo Genes (internal stop)      :: 33 of 128
            Pseudo Genes (multiple problems)  :: 22 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..645
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012484-rid20186543.denovo.149"
                     /strain="NIG 640-05"
                     /db_xref="taxon:1313"
     gene            16..333
                     /locus_tag="VQ862_002216"
     CDS             16..333
                     /locus_tag="VQ862_002216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001856603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HET3116471.1"
                     /translation="MVPQFSRGLPKNLLEISQIVNNLEGKVTNRQLISLLPFVEDPDA
                     ELEALEEEKKKNMEDMPMFNKDNTKPEDEVEDEESGVLGEEESQSDLPADGQGRKAGR
                     PVR"
     gene            242..>645
                     /locus_tag="VQ862_002217"
     CDS             242..>645
                     /locus_tag="VQ862_002217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000795722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head morphogenesis protein"
                     /protein_id="HET3116472.1"
                     /translation="MKNQEYWAKRKANLIYQQMDKAEKQADQFDKVYQEAKTYLDKEV
                     NKIFDKFQRDYGLSQVEARQVLKNMKDKKNLNELRKVLEARPNDPDIQRLLADLDSPA
                     YSFRMKRLERLSDDLDRMRESIYHSEKTGSDA"
BASE COUNT          222 a          123 c          153 g          147 t
ORIGIN      
        1 ctagagtctc attcaatcgt tccacaattc agccgtggtt tgcctaaaaa cttgctggaa
       61 atctctcaga ttgtgaacaa tttggaaggt aaagtgacca ataggcagct tatttctctc
      121 ttgccgtttg tggaagaccc tgacgctgaa ctggaagcct tggaagaaga aaaaaagaag
      181 aacatggaag acatgccgat gttcaacaaa gacaacacga aacccgaaga cgaggtagag
      241 gatgaagaat caggagtatt gggcgaagag gaaagccaat ctgatttacc agcagatgga
      301 caaggccgaa aagcaggcag accagttcga taaggtctat caggaagcca agacttactt
      361 ggataaggaa gtcaataaga tttttgataa gttccaacgt gattatggtc taagtcaggt
      421 agaagctaga caagtcttga agaacatgaa agacaagaaa aatctgaatg aacttcgtaa
      481 agtacttgaa gcgagaccga atgacccgga catccaaaga ttactagctg acttagacag
      541 cccagcttat tctttccgta tgaagcgcct agaacgtttg agtgatgatt tagaccgtat
      601 gcgtgaatct atctatcatt cagaaaagac aggctcagac gcctt
//
LOCUS       DAVBOD010000149          643 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 640-05
            SAMEA1012484-rid20186543.denovo.150, whole genome shotgun sequence.
ACCESSION   DAVBOD010000149 DAVBOD010000000
VERSION     DAVBOD010000149.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012484
            Sequence Read Archive: ERR059358
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 643)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 643)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979948.1
            Genome Coverage       :: 595x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:03:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,266
            CDSs (total)                      :: 2,219
            Genes (coding)                    :: 2,091
            CDSs (with protein)               :: 2,091
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 71 of 128
            Pseudo Genes (incomplete)         :: 50 of 128
            Pseudo Genes (internal stop)      :: 33 of 128
            Pseudo Genes (multiple problems)  :: 22 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..643
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012484-rid20186543.denovo.150"
                     /strain="NIG 640-05"
                     /db_xref="taxon:1313"
     gene            16..333
                     /locus_tag="VQ862_002218"
     CDS             16..333
                     /locus_tag="VQ862_002218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001856603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HET3116473.1"
                     /translation="MVPQFSRGLPKNLLEISQIVNNLEGKVTNRQLISLLPFVEDPDA
                     ELEALEEEKKKNMEDMPMFNQDNTKPEDEVEDEESGVLGEEESQSDLPADGQGRKAGR
                     PVR"
     gene            242..>643
                     /locus_tag="VQ862_002219"
     CDS             242..>643
                     /locus_tag="VQ862_002219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000795722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head morphogenesis protein"
                     /protein_id="HET3116474.1"
                     /translation="MKNQEYWAKRKANLIYQQMDKAEKQADQFDKVYQEAKTYLDKEI
                     NKIFDKFQRDYGLSQVEARQVLKNMKDKKNLNELRKVLEARPNDPNIQRLLADLDSPA
                     YSFRMKRLERLSDDLDRMRESIYHSEKTGSDA"
BASE COUNT          223 a          118 c          151 g          151 t
ORIGIN      
        1 ttagagtctc attcaatcgt tccacaattc agtcgtggtt tgcctaagaa cttgttagaa
       61 atctctcaga tcgtgaacaa ccttgaaggt aaagtgacga atagacagct tatttctctc
      121 ttgccgtttg tggaagaccc tgatgctgag ctagaagcct tggaagaaga gaaaaagaag
      181 aacatggaag acatgccgat gtttaaccaa gacaacacga aacccgaaga cgaggtagag
      241 gatgaagaat caggagtatt gggcgaagag gaaagccaat ctgatttacc agcagatgga
      301 caaggccgaa aagcaggcag accagttcga taaggtctat caggaagcta agacttactt
      361 ggataaggaa atcaataaga ttttcgataa attccaacgt gattatggtc taagtcaggt
      421 agaagctaga caagtcttga agaacatgaa agacaagaaa aatctgaatg aacttcgtaa
      481 agtacttgaa gcgagaccga atgacccgaa catccaaaga ttactagctg acttagatag
      541 tccggcttat tctttccgta tgaagcgtct agaacgtttg agtgatgatt tagaccgtat
      601 gcgtgaatct atctatcatt cagaaaagac aggctcagac gcc
//
LOCUS       DAVBOD010000150          631 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 640-05
            SAMEA1012484-rid20186543.denovo.151, whole genome shotgun sequence.
ACCESSION   DAVBOD010000150 DAVBOD010000000
VERSION     DAVBOD010000150.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012484
            Sequence Read Archive: ERR059358
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 631)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 631)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979948.1
            Genome Coverage       :: 595x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:03:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,266
            CDSs (total)                      :: 2,219
            Genes (coding)                    :: 2,091
            CDSs (with protein)               :: 2,091
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 71 of 128
            Pseudo Genes (incomplete)         :: 50 of 128
            Pseudo Genes (internal stop)      :: 33 of 128
            Pseudo Genes (multiple problems)  :: 22 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..631
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012484-rid20186543.denovo.151"
                     /strain="NIG 640-05"
                     /db_xref="taxon:1313"
     gene            47..408
                     /locus_tag="VQ862_002220"
                     /pseudo
     CDS             47..408
                     /locus_tag="VQ862_002220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895063.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="protein-export chaperone SecB"
BASE COUNT          207 a           76 c          119 g          229 t
ORIGIN      
        1 ggctagtttc ctagtttgct ctttggtttt cattgagtat aacacattgt tagaagttgg
       61 tttaaatttc ctaatcagtt tgttcacatt taccttcgat atattatatc ccatagttaa
      121 ggttggtcat acagatgatt atagtcatgg agccgtaaaa cttagtgttt ctttagttga
      181 caaagatgcc atgaaaaaat atctgtaact gtaataggat attttgaaat aaatatagat
      241 gaaaatatca ccgatattct atacgtaaat ggtactgcta ttctttgtcc ttatttacgt
      301 tctattgttt caatagtttc ggcaattgat agcagtgaag caatgttgct acctaccatt
      361 aatgttttag agttactaga taaatctcaa ccttttgaag aagaataatt tattagctca
      421 ctaaattgag ggtaaggaaa agtaaaagca gtaagaaaaa tgtcttgcat tatacagcaa
      481 ccttttggga atgagtagat ggattgaata aaatttgatt aagagtggat gatttatctg
      541 tagattatta ttggacagtt agtcttgaag tagtctaaga attaggttat aatcagtaga
      601 agccttgcta ataatgagga ggttagttta t
//
LOCUS       DAVBOD010000151          622 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 640-05
            SAMEA1012484-rid20186543.denovo.152, whole genome shotgun sequence.
ACCESSION   DAVBOD010000151 DAVBOD010000000
VERSION     DAVBOD010000151.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012484
            Sequence Read Archive: ERR059358
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 622)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 622)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979948.1
            Genome Coverage       :: 595x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:03:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,266
            CDSs (total)                      :: 2,219
            Genes (coding)                    :: 2,091
            CDSs (with protein)               :: 2,091
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 71 of 128
            Pseudo Genes (incomplete)         :: 50 of 128
            Pseudo Genes (internal stop)      :: 33 of 128
            Pseudo Genes (multiple problems)  :: 22 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..622
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012484-rid20186543.denovo.152"
                     /strain="NIG 640-05"
                     /db_xref="taxon:1313"
     gene            <1..>622
                     /locus_tag="VQ862_002221"
     CDS             <1..>622
                     /locus_tag="VQ862_002221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000212172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3116475.1"
                     /translation="LDTVAPVFESIERSVNKFGDGLSRVYDEHVVPAINSIANAFNGL
                     IDIIQILWEGSWKPFAEFLSNTFGISIETVADLLGGIILEALKLLADTIKLVTDGFTA
                     FSDWCKENKEIISTIASVIGTLATVWQGIKFLSWAEQAGGLAGAFELLSSKVSFIVSG
                     IKNLGLALKALTFDKLVSFGETIYLNALYAKDFVVNSGKTIAQLGKT"
BASE COUNT          181 a           95 c          142 g          204 t
ORIGIN      
        1 attagatact gttgcgcctg tatttgagag cattgaaagg tctgttaaca aatttggcga
       61 tggcttaagt cgtgtttatg atgaacatgt agtccctgct attaactcta ttgctaatgc
      121 ttttaatggg ctaattgaca ttattcaaat actttgggaa ggaagttgga agccttttgc
      181 agagttcttg tctaacacat tcggcataag tattgaaacc gtcgctgatt tactaggcgg
      241 tatcatacta gaggcattga agttactagc tgatacaatc aagctagtaa ccgatggttt
      301 tactgctttt tcagattggt gtaaagaaaa taaagagatt atctccacaa tcgctagtgt
      361 gattggtacg cttgcaaccg tgtggcaagg aattaagttc ttgtcttggg ctgaacaagc
      421 tggaggactt gcaggggcat tcgaattatt aagtagtaag gtttccttta ttgttagcgg
      481 aattaaaaat cttggactag ctttgaaagc tttgacattt gataaattgg tcagcttcgg
      541 agaaaccatc tatttgaatg cgttgtatgc aaaagatttt gttgtcaatt caggtaaaac
      601 aattgcacag ctagggaaaa ct
//
LOCUS       DAVBOD010000152          621 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 640-05
            SAMEA1012484-rid20186543.denovo.153, whole genome shotgun sequence.
ACCESSION   DAVBOD010000152 DAVBOD010000000
VERSION     DAVBOD010000152.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012484
            Sequence Read Archive: ERR059358
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 621)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 621)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979948.1
            Genome Coverage       :: 595x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:03:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,266
            CDSs (total)                      :: 2,219
            Genes (coding)                    :: 2,091
            CDSs (with protein)               :: 2,091
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 71 of 128
            Pseudo Genes (incomplete)         :: 50 of 128
            Pseudo Genes (internal stop)      :: 33 of 128
            Pseudo Genes (multiple problems)  :: 22 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..621
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012484-rid20186543.denovo.153"
                     /strain="NIG 640-05"
                     /db_xref="taxon:1313"
     gene            <1..>621
                     /locus_tag="VQ862_002222"
     CDS             <1..>621
                     /locus_tag="VQ862_002222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HET3116476.1"
                     /translation="NQKFSPEMMVMAKGVNVGISTIYYWIHHGKLGLSKQDLPYPRKG
                     KALKKQASTNFKPAGQSIAQRPEAINLRLENGHYEIDTVLLTRAKNYCLLVLTDRKSR
                     HQIIRLIPNKSAEVVNQALKLILKQHKILSITADNGTEFNRLSDVFSEEHIYYAHPYA
                     SWERGTNENHNRFIRRWLPKGTKKMTPKEVAFIEKWINNYPKKCLD"
BASE COUNT          205 a          124 c          134 g          158 t
ORIGIN      
        1 ataaccaaaa attttcgcct gaaatgatgg tgatggctaa aggggttaac gtgggaattt
       61 caaccattta ctattggatt catcatggaa aattggggtt aagcaagcag gatttgcctt
      121 accctagaaa aggaaaagcg cttaagaaac aggccagcac caactttaaa cctgctggtc
      181 aatccatcgc acagcggcct gaagctatca atcttcgctt ggagaatggg cattatgaga
      241 ttgatacggt tctacttacg agagcgaaaa actactgctt gcttgtcttg acggatcgaa
      301 agagtagaca tcagatcatc cgattgattc caaataaaag tgctgaggtg gtcaatcagg
      361 ctctaaaact catcttaaaa caacacaaga ttctttccat cacggcagat aatggaacgg
      421 aattcaatcg cttgtctgat gtattttctg aggagcacat ttattatgcg cacccctatg
      481 cctcttggga aaggggaact aatgagaatc acaacaggtt cattcgtaga tggttaccta
      541 agggaaccaa gaaaatgact cccaaagaag tcgcattcat cgaaaagtgg attaacaact
      601 atcctaaaaa atgcttggac t
//
LOCUS       DAVBOD010000153          615 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 640-05
            SAMEA1012484-rid20186543.denovo.154, whole genome shotgun sequence.
ACCESSION   DAVBOD010000153 DAVBOD010000000
VERSION     DAVBOD010000153.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012484
            Sequence Read Archive: ERR059358
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 615)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 615)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979948.1
            Genome Coverage       :: 595x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:03:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,266
            CDSs (total)                      :: 2,219
            Genes (coding)                    :: 2,091
            CDSs (with protein)               :: 2,091
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 71 of 128
            Pseudo Genes (incomplete)         :: 50 of 128
            Pseudo Genes (internal stop)      :: 33 of 128
            Pseudo Genes (multiple problems)  :: 22 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..615
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012484-rid20186543.denovo.154"
                     /strain="NIG 640-05"
                     /db_xref="taxon:1313"
     gene            <1..>615
                     /locus_tag="VQ862_002223"
     CDS             <1..>615
                     /locus_tag="VQ862_002223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000084419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="PBSX family phage terminase large subunit"
                     /protein_id="HET3116477.1"
                     /translation="VKGSRGSKKSKTTALNYVVRLLKYSWANLLVIRRYSNTNKQSTY
                     TDFKWACNVLGVTHLFKFNESLPEITIKATGQKILFRGLDDELKITSITVDVGSLCWA
                     WFEEAYQIETEDKFSTVVESIRGSLDVPDFFKQITVTFNPWNERHWLKRVFFDEETRR
                     ADTFATTTTYKCNEWLDEVDIKRYEDLYHTNPRRARIVCDGEWGV"
BASE COUNT          178 a          114 c          146 g          177 t
ORIGIN      
        1 agtcaaaggg tcccgtggtt cgaagaagtc caagacaacc gctttaaact atgttgtccg
       61 tcttttgaaa tattcctggg ccaacttgct tgttattcgt aggtattcga atacaaataa
      121 gcaatcaact tatacggatt ttaaatgggc gtgtaatgtg ttgggggtga ctcatttgtt
      181 taaattcaat gagtctttgc ctgaaataac cataaaagcg actggtcaaa aaatcctatt
      241 ccgtggtttg gatgatgaac tcaaaatcac atctatcacg gtcgatgtcg gcagtctttg
      301 ttgggcatgg ttcgaggaag catatcaaat tgagactgaa gacaagttca gcacggttgt
      361 tgagtctatc cgtggtagct tagatgtacc tgatttcttt aaacaaatca cagtcacatt
      421 taacccgtgg aatgagaggc attggctcaa gcgtgtattc ttcgatgaag agacgagacg
      481 ggctgacaca ttcgctacta caaccactta caaatgcaat gagtggcttg atgaagtcga
      541 tatcaaacgc tatgaggatt tgtatcatac gaaccccaga cgtgctagaa tcgtttgtga
      601 tggcgaatgg ggagt
//
LOCUS       DAVBOD010000154          615 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 640-05
            SAMEA1012484-rid20186543.denovo.155, whole genome shotgun sequence.
ACCESSION   DAVBOD010000154 DAVBOD010000000
VERSION     DAVBOD010000154.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012484
            Sequence Read Archive: ERR059358
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 615)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 615)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979948.1
            Genome Coverage       :: 595x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:03:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,266
            CDSs (total)                      :: 2,219
            Genes (coding)                    :: 2,091
            CDSs (with protein)               :: 2,091
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 71 of 128
            Pseudo Genes (incomplete)         :: 50 of 128
            Pseudo Genes (internal stop)      :: 33 of 128
            Pseudo Genes (multiple problems)  :: 22 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..615
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012484-rid20186543.denovo.155"
                     /strain="NIG 640-05"
                     /db_xref="taxon:1313"
     gene            <1..377
                     /locus_tag="VQ862_002224"
     CDS             <1..377
                     /locus_tag="VQ862_002224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000880678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HET3116478.1"
                     /translation="KETYTKLVGLKEVPEFGIELEKVENTTLEDKVKKYEFGIGDVGE
                     LEYKFSYNNSSATAPYRVLRKAADDKKKLYFEQTYPDGTKVKFEGQVSVKLGGGGVNA
                     VIEFTLKIALQSELEFTDGIGG"
     gene            382..>615
                     /locus_tag="VQ862_002225"
     CDS             382..>615
                     /locus_tag="VQ862_002225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001185634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3116479.1"
                     /translation="MALKYTTWKVTDEKELKLRLTSHQAATVEEKIGMNLLKIFMPEA
                     GEEFTLPPLKVMLLLVHGALQQYEHGYSFEDVYD"
BASE COUNT          197 a           93 c          146 g          179 t
ORIGIN      
        1 ctaaagaaac ttatactaaa cttgttggat tgaaagaagt gccagagttt ggtattgaac
       61 tcgaaaaagt agaaaatact actcttgaag ataaagttaa gaagtacgag tttggtattg
      121 gggacgtagg agaacttgag tacaagttct cttataataa ttcaagcgca actgctcctt
      181 atcgtgtatt gcgtaaggca gcggatgaca agaaaaaact ctactttgag caaacatatc
      241 cagacgggac taaggttaaa tttgaaggtc aagtatctgt taagttaggc ggtggcggtg
      301 tcaatgccgt tatcgagttc acccttaaaa ttgctttgca gtcagagttg gaatttacag
      361 acggtattgg aggttaatta aatggcgtta aaatacacaa cttggaaagt tactgacgaa
      421 aaagagttga agctacgttt gacatctcat caagctgcaa ctgtggaaga aaaaatcggc
      481 atgaacttgt taaagatttt catgcctgaa gctggcgaag agttcacttt accgcctttg
      541 aaagttatgc tgttgttagt tcatggagcc ttgcagcagt atgaacatgg gtattctttt
      601 gaggatgtct atgat
//
LOCUS       DAVBOD010000155          615 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 640-05
            SAMEA1012484-rid20186543.denovo.156, whole genome shotgun sequence.
ACCESSION   DAVBOD010000155 DAVBOD010000000
VERSION     DAVBOD010000155.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012484
            Sequence Read Archive: ERR059358
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 615)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 615)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979948.1
            Genome Coverage       :: 595x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:03:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,266
            CDSs (total)                      :: 2,219
            Genes (coding)                    :: 2,091
            CDSs (with protein)               :: 2,091
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 71 of 128
            Pseudo Genes (incomplete)         :: 50 of 128
            Pseudo Genes (internal stop)      :: 33 of 128
            Pseudo Genes (multiple problems)  :: 22 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..615
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012484-rid20186543.denovo.156"
                     /strain="NIG 640-05"
                     /db_xref="taxon:1313"
     gene            <1..377
                     /locus_tag="VQ862_002226"
     CDS             <1..377
                     /locus_tag="VQ862_002226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000880678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HET3116480.1"
                     /translation="KGTYTKLVGLKEVPEFGIELEKVENTTLEDTVKKYEFGIGDIGE
                     LEYKFSYNNSSATAPYRVLRKAADDKKKLYFEQAYPDGTKVNFEGQVSVKLGGGGVNA
                     VIEFTLKIALQSELEFTDGVGG"
     gene            382..>615
                     /locus_tag="VQ862_002227"
     CDS             382..>615
                     /locus_tag="VQ862_002227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001185634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3116481.1"
                     /translation="MALKYTTWKVTDEKELKLRLTSHQAATVEEKIGMNLLKIFMPEA
                     GEEFTLPPLKVMLLLVHGALQQYEHGYSFEDVYD"
BASE COUNT          193 a          104 c          148 g          170 t
ORIGIN      
        1 ctaaaggaac ttatactaaa cttgttggat tgaaagaagt gccagagttt ggtattgaac
       61 tcgaaaaagt agaaaatact actcttgaag atacagtgaa gaagtacgag tttggtattg
      121 gggacatagg agaacttgag tacaagttct cttataataa ttcaagcgca actgctcctt
      181 atcgtgtatt gcgtaaggca gcagacgaca agaagaaact ctacttcgag caagcatacc
      241 cagacggtac taaggtcaat tttgaaggcc aagtatctgt taagcttggc ggtggcggtg
      301 tcaatgccgt tatcgagttc acacttaaga ttgccttgca gtcagagttg gaatttacag
      361 acggtgttgg aggttaatta aatggcgtta aaatacacaa cttggaaagt tactgacgaa
      421 aaagagttga agctacgttt gacatctcat caagctgcaa ctgtggaaga aaaaatcggc
      481 atgaacttgc taaagatttt catgcctgaa gctggcgaag agttcacttt accgcctttg
      541 aaagttatgc tgttgttagt tcatggagcc ttgcagcagt atgaacatgg gtattccttt
      601 gaagatgtct acgac
//
LOCUS       DAVBOD010000156          609 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 640-05
            SAMEA1012484-rid20186543.denovo.157, whole genome shotgun sequence.
ACCESSION   DAVBOD010000156 DAVBOD010000000
VERSION     DAVBOD010000156.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012484
            Sequence Read Archive: ERR059358
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 609)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 609)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979948.1
            Genome Coverage       :: 595x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:03:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,266
            CDSs (total)                      :: 2,219
            Genes (coding)                    :: 2,091
            CDSs (with protein)               :: 2,091
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 71 of 128
            Pseudo Genes (incomplete)         :: 50 of 128
            Pseudo Genes (internal stop)      :: 33 of 128
            Pseudo Genes (multiple problems)  :: 22 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..609
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012484-rid20186543.denovo.157"
                     /strain="NIG 640-05"
                     /db_xref="taxon:1313"
     gene            <1..>609
                     /locus_tag="VQ862_002228"
     CDS             <1..>609
                     /locus_tag="VQ862_002228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639856.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate binding domain-containing protein"
                     /protein_id="HET3116482.1"
                     /translation="GSIRQEILNATKDKASKSELTQTAEELASRIASVQVGGINLLRN
                     TASLLIGDRSKGCWMSASGGNGRAISVEVLDPPKKMIKNMIRVIENTNGGNKDLTQLV
                     RLRIGEKYTISCYARIASDSPNANVNLLFRSWANNTDLTRKFQKSISHKNWQKYSFTF
                     TADAIENSIQFGQSGAGIIEICAPKIESGTLATDYSEAPEDIE"
BASE COUNT          203 a          108 c          141 g          157 t
ORIGIN      
        1 ggctctatcc gtcaggaaat cctgaacgca accaaggata aagccagcaa gtcagaactc
       61 acgcagacag ctgaggagct agctagtcgg attgcgagtg tgcaggtcgg aggaatcaac
      121 ctcttgcgta atactgcgag tttgttgatt ggcgatcgtt caaaaggatg ttggatgagt
      181 gcaagcggag gaaatgggcg agcgattagc gtagaagttt tggatcctcc caaaaaaatg
      241 ataaaaaaca tgattcgtgt tattgaaaat acgaatggtg gaaataaaga tttaactcaa
      301 cttgttagat tgcgaattgg tgaaaagtac acgatttctt gttatgcaag gattgctagc
      361 gatagcccaa atgcaaacgt gaacttgcta tttcgttcgt gggcaaataa taccgattta
      421 actcgcaaat ttcagaaatc catctctcat aaaaattggc aaaaatattc atttacattt
      481 actgctgatg caattgaaaa ttcaattcaa tttggacaat ctggcgcagg aattatcgaa
      541 atatgcgctc cgaaaatcga atcaggaacg ttagcgactg attacagcga agctcctgaa
      601 gatatagaa
//
LOCUS       DAVBOD010000157          599 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 640-05
            SAMEA1012484-rid20186543.denovo.158, whole genome shotgun sequence.
ACCESSION   DAVBOD010000157 DAVBOD010000000
VERSION     DAVBOD010000157.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012484
            Sequence Read Archive: ERR059358
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 599)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 599)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979948.1
            Genome Coverage       :: 595x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:03:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,266
            CDSs (total)                      :: 2,219
            Genes (coding)                    :: 2,091
            CDSs (with protein)               :: 2,091
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 71 of 128
            Pseudo Genes (incomplete)         :: 50 of 128
            Pseudo Genes (internal stop)      :: 33 of 128
            Pseudo Genes (multiple problems)  :: 22 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..599
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012484-rid20186543.denovo.158"
                     /strain="NIG 640-05"
                     /db_xref="taxon:1313"
     gene            complement(21..500)
                     /locus_tag="VQ862_002229"
     CDS             complement(21..500)
                     /locus_tag="VQ862_002229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000588926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HET3116483.1"
                     /translation="MIKELYEEVQGTVYKCRNEYYLHLWELSDWDQEGMLCLHELISR
                     EEGLVDDIPRLRKYFKTKFRNRILDYIRKQESQKRRYDKEPYEEVGEISHRISEGGLW
                     LDDYYLFHETLRDYRNKQSKEKQEELERVLSNERFRGRQRVLRDLRIVFKEFTIRTH"
BASE COUNT          160 a          139 c           78 g          222 t
ORIGIN      
        1 attttttttt gcatgactta ctagtgggta cggatagtaa actccttaaa cacaatgcgt
       61 aagtctctta atactctttg acgccctcga aatcgttcat tgcttaagac gcgttctagt
      121 tcttcttgtt tctctttact ttgtttgttt ctataatctc ttagtgtttc atgaaagaga
      181 taataatcat ctagccagag acccccctca cttatacgat gactgatctc tcccacttct
      241 tcatagggtt ctttatcgta tctacgcttc tgactttcct gcttacggat atagtctaaa
      301 attcgatttc gaaacttggt tttgaaatat ttccttaaac gtggaatatc gtctaccagt
      361 ccttcttctc tactaatcaa ttcatgtaag cagagcatgc cttcttggtc ccaatccgac
      421 aattcccata aatgaaggta atattcattt ctacacttat aaacagtccc ttggacttct
      481 tcatacaatt ctttaatcat aattttcccc tttctagata cagtctaaca gattagaaaa
      541 cacatttgtt ccattttctc cattctgttc cctttagctc ctaaactgca caaaaaaga
//
LOCUS       DAVBOD010000158          536 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 640-05
            SAMEA1012484-rid20186543.denovo.159, whole genome shotgun sequence.
ACCESSION   DAVBOD010000158 DAVBOD010000000
VERSION     DAVBOD010000158.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012484
            Sequence Read Archive: ERR059358
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 536)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 536)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979948.1
            Genome Coverage       :: 595x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:03:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,266
            CDSs (total)                      :: 2,219
            Genes (coding)                    :: 2,091
            CDSs (with protein)               :: 2,091
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 71 of 128
            Pseudo Genes (incomplete)         :: 50 of 128
            Pseudo Genes (internal stop)      :: 33 of 128
            Pseudo Genes (multiple problems)  :: 22 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..536
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012484-rid20186543.denovo.159"
                     /strain="NIG 640-05"
                     /db_xref="taxon:1313"
     gene            complement(<1..534)
                     /locus_tag="VQ862_002230"
     CDS             complement(<1..534)
                     /locus_tag="VQ862_002230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HET3116484.1"
                     /translation="MEQIKDGIIVSCQALPHEPLYTEAGGVIPLLVKAAEQGGAVGIR
                     ANSVRDIKEIKEVTKLPIIGIIKRDYPPQEPFITATMKEVDELAELDIEVIALDCTKR
                     ERYDGLEIQEFIRQVKEKYPNQLLMADTSIFEEGLAAVEAGIDFVGTTLSGYTSYSPK
                     VDGPDFELIKKLCDAGVD"
BASE COUNT          141 a          133 c          103 g          159 t
ORIGIN      
        1 atctacaccg gcatcacaga gtttcttaat caattcaaaa tctggaccgt ctacttttgg
       61 actgtaggat gtgtagcctg ataaggttgt tccgacaaag tcaattcctg cttctacagc
      121 tgctagccct tcttcgaaga tactagtatc agccatcaaa agctgattag gatatttctc
      181 cttaacctga cgaatgaact cttgaatttc caaaccatcg tagcgttcac gcttggtaca
      241 atccagagca atcacctcga tgtccagttc tgccaattca tcaacttctt tcatagtagc
      301 cgtgatgaag ggttcctgag gtggataatc acgtttgata atcccaatga ttggaagttt
      361 agtgacttcc ttaatttcct tgatatcgcg aacactgttt gctcggatac cgactgctcc
      421 accttgctca gccgctttga ccagcaaggg aatcacccct cccgcttctg tataaagcgg
      481 ttcatgagga agagcctgac aagaaacgat gattccatct ttgatttgct caatca
//
LOCUS       DAVBOD010000159          535 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 640-05
            SAMEA1012484-rid20186543.denovo.160, whole genome shotgun sequence.
ACCESSION   DAVBOD010000159 DAVBOD010000000
VERSION     DAVBOD010000159.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012484
            Sequence Read Archive: ERR059358
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 535)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 535)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979948.1
            Genome Coverage       :: 595x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:03:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,266
            CDSs (total)                      :: 2,219
            Genes (coding)                    :: 2,091
            CDSs (with protein)               :: 2,091
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 71 of 128
            Pseudo Genes (incomplete)         :: 50 of 128
            Pseudo Genes (internal stop)      :: 33 of 128
            Pseudo Genes (multiple problems)  :: 22 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..535
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012484-rid20186543.denovo.160"
                     /strain="NIG 640-05"
                     /db_xref="taxon:1313"
     gene            complement(<1..110)
                     /locus_tag="VQ862_002231"
     CDS             complement(<1..110)
                     /locus_tag="VQ862_002231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET3116485.1"
                     /translation="MVNCEPLEAYRQLAEAELVGCWAHVRRKFFEATPKQA"
     gene            complement(183..410)
                     /locus_tag="VQ862_002232"
     CDS             complement(183..410)
                     /locus_tag="VQ862_002232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001827253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET3116486.1"
                     /translation="MRERLLTQPLLHADETSYRVLESHSHLTYYWTFLSGKVENQAIT
                     LYHHDQSRSGSVVQEFLGDYSGYVHCDMLRQ"
BASE COUNT          155 a          125 c          108 g          147 t
ORIGIN      
        1 gcttgcttgg gggtcgcttc aaaaaatttc cttctcacat gcgcccaaca tccaacaagt
       61 tcagcttctg ccagttgacg ataagcttct agcggttcgc agtttaccaa gcttagcgtc
      121 gccttgctcc taaaccttgg actgctatcg cataggcaga actagaggac taaagtccta
      181 agttactgcc gcaacatatc acaatgaaca tagccagaat aatctcctag gaattcttgt
      241 actaccgaac cactccgact ctgatcatga tggtacagcg tgattgcttg attctcaact
      301 ttcccagaca aaaaggtcca atagtaggtc agatggctat gactctctag aacccgataa
      361 gaagtttcat ccgcatgaag taagggctga gtcaatagtc tctctcgcaa gaggttataa
      421 aggggcttta ggaataggag ctttcacaag cttatccaga tgattatctt ttactcgtta
      481 tggacaatgc tatatggcat aaatcaagta ccttaaagat tccgactaat attgg
//
LOCUS       DAVBOD010000160          516 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 640-05
            SAMEA1012484-rid20186543.denovo.161, whole genome shotgun sequence.
ACCESSION   DAVBOD010000160 DAVBOD010000000
VERSION     DAVBOD010000160.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012484
            Sequence Read Archive: ERR059358
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 516)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 516)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979948.1
            Genome Coverage       :: 595x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:03:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,266
            CDSs (total)                      :: 2,219
            Genes (coding)                    :: 2,091
            CDSs (with protein)               :: 2,091
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 71 of 128
            Pseudo Genes (incomplete)         :: 50 of 128
            Pseudo Genes (internal stop)      :: 33 of 128
            Pseudo Genes (multiple problems)  :: 22 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..516
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012484-rid20186543.denovo.161"
                     /strain="NIG 640-05"
                     /db_xref="taxon:1313"
     gene            1..516
                     /locus_tag="VQ862_002233"
                     /pseudo
     CDS             1..516
                     /locus_tag="VQ862_002233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; incomplete; missing N-terminus and
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="winged helix-turn-helix domain-containing
                     protein"
BASE COUNT          156 a          100 c          114 g          146 t
ORIGIN      
        1 aatatgagga gttcggactc gactctctcc ttcaagaaac acgtggtggt cgtaaccatg
       61 catatatgac agttgaggaa gagaaagcct ttcttgcccg ccatttgaag gctacagagg
      121 caggagaatt tgttacaatt gatgccttat ttcaggctta taaaaaggag ttaggtcatt
      181 cctacacacg tgatgccttc tatcaactgt tgaagcgcca tggttggcga aatattacgc
      241 cacgtccaga acatcctaag aaagcagacg ctcaaaccat tgttgcgtct aaaaataaaa
      301 tctcaattca agaagacaag aaagcgtttt aaatatagta gacgttttca taaggttcgc
      361 ttgatgtacc aagatgaggc tggtttcggt agaatcagta aactgggatc ttgttggtct
      421 ccaataggag taggtccaca tgtccatagt cactatatac gagaatttcg ctattattat
      481 ggagctgttg atgcctatac aggcgaatca tttttc
//
LOCUS       DAVBOD010000161          501 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 640-05
            SAMEA1012484-rid20186543.denovo.162, whole genome shotgun sequence.
ACCESSION   DAVBOD010000161 DAVBOD010000000
VERSION     DAVBOD010000161.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012484
            Sequence Read Archive: ERR059358
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 501)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 501)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979948.1
            Genome Coverage       :: 595x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:03:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,266
            CDSs (total)                      :: 2,219
            Genes (coding)                    :: 2,091
            CDSs (with protein)               :: 2,091
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 71 of 128
            Pseudo Genes (incomplete)         :: 50 of 128
            Pseudo Genes (internal stop)      :: 33 of 128
            Pseudo Genes (multiple problems)  :: 22 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..501
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012484-rid20186543.denovo.162"
                     /strain="NIG 640-05"
                     /db_xref="taxon:1313"
     gene            <1..>501
                     /locus_tag="VQ862_002234"
     CDS             <1..>501
                     /locus_tag="VQ862_002234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000756162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HET3116487.1"
                     /translation="FGENKIFESIDNLFDIIDGDRGKNYPKSDELFSEEYCLFLNTKN
                     VTKNGFSFDTKQFITKTKDKLLRKGKLERYDIVLTTRGTVGNVAYYDELIKYKHLRIN
                     SGMVILRPKTPNLNQKFIIHVLRNNNYSRVISGSAQPQLPITKLKKILLPLPPLALQN
                     EFADFVV"
BASE COUNT          191 a           75 c           83 g          152 t
ORIGIN      
        1 gtttggggaa aataaaatat ttgaaagcat tgataactta tttgatatta tagatggtga
       61 taggggcaaa aattatccta aatcagatga gttgtttagt gaggagtact gtttattttt
      121 aaatacaaag aatgttacta aaaacggatt ttcattcgat acaaagcaat ttatcactaa
      181 aacaaaggat aaattacttc gaaaaggcaa acttgagcgt tatgatatag tcttgacaac
      241 aagaggtact gttggaaatg tagcgtacta cgatgaatta ataaaatata aacatttacg
      301 tataaattca ggtatggtaa tattacgtcc caagacacca aatctaaatc agaaatttat
      361 tatccatgtt ttaaggaata ataattatag tcgagtgata tcaggaagtg ctcagcctca
      421 gttaccaatt acaaaattaa aaaaaatact tctccccctc cccccactag ccctccaaaa
      481 tgagttcgca gactttgtag t
//
LOCUS       DAVBOD010000162          496 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 640-05
            SAMEA1012484-rid20186543.denovo.163, whole genome shotgun sequence.
ACCESSION   DAVBOD010000162 DAVBOD010000000
VERSION     DAVBOD010000162.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012484
            Sequence Read Archive: ERR059358
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 496)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 496)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979948.1
            Genome Coverage       :: 595x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:03:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,266
            CDSs (total)                      :: 2,219
            Genes (coding)                    :: 2,091
            CDSs (with protein)               :: 2,091
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 71 of 128
            Pseudo Genes (incomplete)         :: 50 of 128
            Pseudo Genes (internal stop)      :: 33 of 128
            Pseudo Genes (multiple problems)  :: 22 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..496
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012484-rid20186543.denovo.163"
                     /strain="NIG 640-05"
                     /db_xref="taxon:1313"
     gene            <1..>496
                     /locus_tag="VQ862_002235"
     CDS             <1..>496
                     /locus_tag="VQ862_002235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
                     /protein_id="HET3116488.1"
                     /translation="FDPAQITSRTANGVAVPHGDHYHFIPYSQLSPLEEKLARIIPLR
                     YRSNHWVPDSRPEQPSPQPTPEPSPSPQPAPNPQPAPSNPIDEKLVKEAVRKVGDGYV
                     FEENGVPRYIPAKDLSAETAAGIDSKLAKQESLSHKLGAKKTDLPSSDREFYNKAYDL
                     LARI"
BASE COUNT          158 a          122 c           96 g          120 t
ORIGIN      
        1 ttttcgaccc agcgcaaatc acaagtcgaa ccgccaatgg tgttgctgta ccgcacggag
       61 accattatca ctttattcct tattcacaac tgtcaccttt ggaagaaaaa ttggctcgta
      121 ttattcccct tcgttatcgt tcaaaccatt gggtaccaga ttcaagacca gaacaaccaa
      181 gtccacaacc gactccggaa cctagtccaa gtccgcaacc tgcaccaaat cctcaaccag
      241 ctccaagcaa tccaattgat gagaaattgg tcaaagaagc tgttcgaaaa gtaggcgatg
      301 gttatgtctt tgaggagaat ggagttcctc gttatatccc agccaaggat ctttcagcag
      361 aaacagcagc aggcattgat agcaaactgg ccaagcagga aagtttatct cataagctag
      421 gagctaagaa aactgacctc ccatctagtg atagagaatt ttacaataag gcttatgact
      481 tactagcaag aattca
//
LOCUS       DAVBOD010000163          492 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 640-05
            SAMEA1012484-rid20186543.denovo.164, whole genome shotgun sequence.
ACCESSION   DAVBOD010000163 DAVBOD010000000
VERSION     DAVBOD010000163.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012484
            Sequence Read Archive: ERR059358
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 492)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 492)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979948.1
            Genome Coverage       :: 595x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:03:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,266
            CDSs (total)                      :: 2,219
            Genes (coding)                    :: 2,091
            CDSs (with protein)               :: 2,091
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 71 of 128
            Pseudo Genes (incomplete)         :: 50 of 128
            Pseudo Genes (internal stop)      :: 33 of 128
            Pseudo Genes (multiple problems)  :: 22 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..492
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012484-rid20186543.denovo.164"
                     /strain="NIG 640-05"
                     /db_xref="taxon:1313"
     gene            complement(<1..>492)
                     /locus_tag="VQ862_002236"
     CDS             complement(<1..>492)
                     /locus_tag="VQ862_002236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001854690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HET3116489.1"
                     /translation="HNLGQIPIIEYRNNHFAIGDYEQQISLIDAYNSLMGNRVNDKEQ
                     AVESILVLYGTQLADTPEDAKVAMKILSEEGLLELPGDSARAEFLKNTLDESATEILR
                     TALKEDIYTFSHVPNLTDENFAGNTSGVAMEFKLMGLEMITKTKEANYKRGLRQRIAI
                     FAH"
BASE COUNT          134 a          119 c           92 g          147 t
ORIGIN      
        1 taatgagcaa aaatcgcaat acgctgacgc aatcctcgct tatagttcgc ttccttggtc
       61 ttagtaatca tctcaaggcc catcagctta aattccatgg ctacgcctga tgtattccct
      121 gcgaaattct catcagtcaa attaggcaca tggctaaatg tgtagatgtc ctctttaaga
      181 gctgtacgca agatttcagt agcactttcg tccagcgtat tcttcaagaa ctcagccctt
      241 gcactatcgc ccggcaattc caaaagacct tcttcagaaa gaatcttcat tgctacctta
      301 gcgtcttctg gagtgtctgc taactgcgtg ccatacaaga caaggataga ctctacagcc
      361 tgttccttat cattgacacg attccccatc aaggaattat aagcgtctat caagctaatt
      421 tgttgctcat agtcaccaat tgcaaagtga ttgttgcgat attcgataat tgggatttga
      481 ccaaggttgt ga
//
LOCUS       DAVBOD010000164          476 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 640-05
            SAMEA1012484-rid20186543.denovo.165, whole genome shotgun sequence.
ACCESSION   DAVBOD010000164 DAVBOD010000000
VERSION     DAVBOD010000164.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012484
            Sequence Read Archive: ERR059358
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 476)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979948.1
            Genome Coverage       :: 595x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:03:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,266
            CDSs (total)                      :: 2,219
            Genes (coding)                    :: 2,091
            CDSs (with protein)               :: 2,091
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 71 of 128
            Pseudo Genes (incomplete)         :: 50 of 128
            Pseudo Genes (internal stop)      :: 33 of 128
            Pseudo Genes (multiple problems)  :: 22 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012484-rid20186543.denovo.165"
                     /strain="NIG 640-05"
                     /db_xref="taxon:1313"
     gene            complement(91..228)
                     /locus_tag="VQ862_002237"
     CDS             complement(91..228)
                     /locus_tag="VQ862_002237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001067591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3116490.1"
                     /translation="MNPDRAEEYFCRGCQGENPEDIEFYDEQLQAEKVEALNIRLEVK
                     N"
     gene            complement(372..446)
                     /locus_tag="VQ862_002238"
                     /pseudo
     CDS             complement(372..446)
                     /locus_tag="VQ862_002238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000410533.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="cell envelope"
BASE COUNT          170 a           79 c           69 g          158 t
ORIGIN      
        1 tatgtgcttc aagtatataa aaaggcgtaa aaatacgcct atagataatg gggttgaaat
       61 aggtttattg ttgatgagat tgtagataat tcaatttttt acttccaatc gaatattcaa
      121 agcctccacc ttttctgcct gtaattgttc atcataaaat tcaatatctt caggattttc
      181 cccttgacaa cctcggcaga aatattcttc cgctcgatca ggattcaaaa atcgacaagc
      241 acaaacaaaa cagtcgccat catcatttat tgagataata tagtagattg aaataagatg
      301 taaacaaatc gattaggaaa gttaaattaa tttctagaaa tttttagcag atgtagtgta
      361 ctattctagt ctcaatttac tatggcttca aatatatctt tcgaaaaaat atttacagat
      421 gtgtaatttt gaagcttgca aaagttagcc ccaattattc acccctaatc taaaaa
//
LOCUS       DAVBOD010000165          473 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 640-05
            SAMEA1012484-rid20186543.denovo.166, whole genome shotgun sequence.
ACCESSION   DAVBOD010000165 DAVBOD010000000
VERSION     DAVBOD010000165.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012484
            Sequence Read Archive: ERR059358
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 473)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 473)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979948.1
            Genome Coverage       :: 595x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:03:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,266
            CDSs (total)                      :: 2,219
            Genes (coding)                    :: 2,091
            CDSs (with protein)               :: 2,091
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 71 of 128
            Pseudo Genes (incomplete)         :: 50 of 128
            Pseudo Genes (internal stop)      :: 33 of 128
            Pseudo Genes (multiple problems)  :: 22 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..473
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012484-rid20186543.denovo.166"
                     /strain="NIG 640-05"
                     /db_xref="taxon:1313"
     gene            complement(<1..>473)
                     /locus_tag="VQ862_002239"
     CDS             complement(<1..>473)
                     /locus_tag="VQ862_002239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000795723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="minor capsid protein"
                     /protein_id="HET3116491.1"
                     /translation="TYSTNIWKNTGKLTSSIKDELLISLMTGRDTRETAQAIAERFNV
                     GQNDARRLVRTESAFFHNQMELLNYEEADIEKYIFVAVLDKRTSRICQEHDNQVYDRD
                     KAVPGVNCPPMHPWCRSTTVGYDEDADYSKLKRRARNPETGKVEYVPADMTYKEW"
BASE COUNT          108 a          122 c           94 g          149 t
ORIGIN      
        1 taccactctt tataagtcat atcggcaggc acgtactcaa ctttacctgt ctctggattc
       61 cttgctctgc gcttcaactt gctgtagtct gcgtcctcat cgtatccgac agtagtagac
      121 ctacaccaag ggtgcatagg cggacaattg acaccaggga cagccttatc cctatcatag
      181 acctgattgt catgctcctg acaaatgcgt gatgtacgct tgtctaagac ggccacaaag
      241 atatacttct ctatatccgc ttcctcatag ttgagtagct ccatttggtt atgaaaaaag
      301 gctgattctg tccgaaccaa acgccttgca tcgttctgcc ccacattgaa ccgctcagca
      361 attgcttgtg cagtttctcg tgtatctcgg cctgtcataa ggcttatgag taattcatct
      421 tttatgcttg atgtaagctt ccctgtattc ttccagatgt ttgttgagta cgt
//
LOCUS       DAVBOD010000166          447 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 640-05
            SAMEA1012484-rid20186543.denovo.167, whole genome shotgun sequence.
ACCESSION   DAVBOD010000166 DAVBOD010000000
VERSION     DAVBOD010000166.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012484
            Sequence Read Archive: ERR059358
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 447)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 447)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979948.1
            Genome Coverage       :: 595x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:03:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,266
            CDSs (total)                      :: 2,219
            Genes (coding)                    :: 2,091
            CDSs (with protein)               :: 2,091
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 71 of 128
            Pseudo Genes (incomplete)         :: 50 of 128
            Pseudo Genes (internal stop)      :: 33 of 128
            Pseudo Genes (multiple problems)  :: 22 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..447
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012484-rid20186543.denovo.167"
                     /strain="NIG 640-05"
                     /db_xref="taxon:1313"
     gene            1..447
                     /locus_tag="VQ862_002240"
                     /pseudo
     CDS             1..447
                     /locus_tag="VQ862_002240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="internal stop; incomplete; missing N-terminus and
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
BASE COUNT          174 a           72 c           87 g          114 t
ORIGIN      
        1 aaaaatcgtt actattctcc tgatttaaaa caagaaatga ttaataaagt ctgacatgaa
       61 ggctggacta aagatagagt ttctcttgaa tactgtctcc caagtcgtac gatacttctt
      121 aactggctag cacaatacag gaaaaacggg tatactattg ttgagaaaac aagagggaga
      181 gtacctgaga gcggaaaatg ccatcctaaa aaagttaaga gaactccgat tgaaggagga
      241 aaaagagaaa gaagaaagac agaaattgtt caagaattaa tgactgagtt ttcgttagat
      301 attcttctaa aagccattaa actagctcgt tcgacctact actatcactt gaaacagcta
      361 gataaaacag ataaggacca agagcttaaa gctgaaattc aatccatttt tatcgaacac
      421 aagggaaatt atggttatcg tcggatt
//
LOCUS       DAVBOD010000167          377 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 640-05
            SAMEA1012484-rid20186543.denovo.168, whole genome shotgun sequence.
ACCESSION   DAVBOD010000167 DAVBOD010000000
VERSION     DAVBOD010000167.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012484
            Sequence Read Archive: ERR059358
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 377)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 377)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979948.1
            Genome Coverage       :: 595x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:03:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,266
            CDSs (total)                      :: 2,219
            Genes (coding)                    :: 2,091
            CDSs (with protein)               :: 2,091
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 71 of 128
            Pseudo Genes (incomplete)         :: 50 of 128
            Pseudo Genes (internal stop)      :: 33 of 128
            Pseudo Genes (multiple problems)  :: 22 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..377
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012484-rid20186543.denovo.168"
                     /strain="NIG 640-05"
                     /db_xref="taxon:1313"
     gene            complement(1..377)
                     /locus_tag="VQ862_002241"
                     /pseudo
     CDS             complement(1..377)
                     /locus_tag="VQ862_002241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="frameshifted; incomplete; missing N-terminus and
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
BASE COUNT          100 a           67 c           71 g          139 t
ORIGIN      
        1 agtacttact ggaatggcaa attcagtcac atctgtgtag cactgttcca ttgttttaga
       61 gccttcaaat tggccttgaa tgagattctc tgccttcttg ccaacgtctc ctttaatgag
      121 aagaatattt tcgtttctgt cgcgttttag cttgtaaatt gagtactttc atcaagcctt
      181 gaactctttt atgatttacc agataagcac gatttcttag ttctaaatga atacagcgat
      241 aagcataatt tcccttgtgt tcgataaaaa tggattgaat ttcagcttta agctcttggt
      301 ccttatctgg tttgtctagc tgtttcaagt gatagtagta ggtccaacga gctagtttaa
      361 tagcttttag aagaaga
//
LOCUS       DAVBOD010000168          356 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 640-05
            SAMEA1012484-rid20186543.denovo.169, whole genome shotgun sequence.
ACCESSION   DAVBOD010000168 DAVBOD010000000
VERSION     DAVBOD010000168.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012484
            Sequence Read Archive: ERR059358
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 356)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 356)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979948.1
            Genome Coverage       :: 595x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:03:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,266
            CDSs (total)                      :: 2,219
            Genes (coding)                    :: 2,091
            CDSs (with protein)               :: 2,091
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 71 of 128
            Pseudo Genes (incomplete)         :: 50 of 128
            Pseudo Genes (internal stop)      :: 33 of 128
            Pseudo Genes (multiple problems)  :: 22 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..356
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012484-rid20186543.denovo.169"
                     /strain="NIG 640-05"
                     /db_xref="taxon:1313"
     gene            <1..>356
                     /locus_tag="VQ862_002242"
     CDS             <1..>356
                     /locus_tag="VQ862_002242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
                     /protein_id="HET3116492.1"
                     /translation="GRQVDFEALDNLLERLKDVSSDKVKLVEDILAFLAPIRHPERLG
                     KPNAQITYTDDEIQVAKLAGKYTTEDGYIFDPRDITSDEGDAYVTPHMTHSHWIKKDS
                     LSEAERAAAQAYAKEKG"
BASE COUNT          112 a           67 c           87 g           90 t
ORIGIN      
        1 ggtcgacaag ttgattttga ggctttggat aacctgttgg aacgactcaa ggatgtctca
       61 agtgataaag tcaagttagt ggaagatatt cttgccttct tagctccgat tcgtcatcca
      121 gaacgtttag gaaaaccaaa tgcgcaaatt acctacactg atgatgagat tcaagtagcc
      181 aagttggcag gcaagtacac aacagaagac ggttatatct ttgatcctcg tgatataacc
      241 agtgatgagg gggatgccta tgtaactcca catatgaccc atagccactg gattaaaaaa
      301 gatagtttgt ctgaagctga gagagcggca gcccaggctt atgctaaaga gaaagg
//
LOCUS       DAVBOD010000169          352 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 640-05
            SAMEA1012484-rid20186543.denovo.170, whole genome shotgun sequence.
ACCESSION   DAVBOD010000169 DAVBOD010000000
VERSION     DAVBOD010000169.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012484
            Sequence Read Archive: ERR059358
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 352)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 352)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979948.1
            Genome Coverage       :: 595x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:03:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,266
            CDSs (total)                      :: 2,219
            Genes (coding)                    :: 2,091
            CDSs (with protein)               :: 2,091
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 71 of 128
            Pseudo Genes (incomplete)         :: 50 of 128
            Pseudo Genes (internal stop)      :: 33 of 128
            Pseudo Genes (multiple problems)  :: 22 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..352
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012484-rid20186543.denovo.170"
                     /strain="NIG 640-05"
                     /db_xref="taxon:1313"
     gene            complement(<1..>352)
                     /locus_tag="VQ862_002243"
     CDS             complement(<1..>352)
                     /locus_tag="VQ862_002243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET3116493.1"
                     /translation="KTGQYYLIKLKKNTVLSRLGDLSLPCPQDEDLTILPHSAYSETL
                     YQAGSWSHKRRVCQFSERKEGNLFYDVISLVTNMTSGTSQDQFQLYRGRGQAENFIKE
                     MKEGFFGDKTDSSTL"
BASE COUNT           89 a           74 c           84 g          105 t
ORIGIN      
        1 ttaaggttga actatccgtt ttatcgccaa aaaatccctc cttcatctcc ttgatgaaat
       61 tctcggcttg accacgtcca cgataaagct gaaactggtc ttggcttgtt ccactcgtca
      121 tatttgtaac gagagaaata acatcgtaga acaagtttcc ttcttttcgt tcagagaact
      181 ggcagacacg acgcttgtgc gaccaagatc ctgcttgata gagagtttct gagtaggcgg
      241 agtggggcaa gatggttaag tcctcatcct gtgggcaagg gagggaaagg tctccaagac
      301 ggctcagaac agtatttttc ttgagtttta tgaggtagta ttgccctgtt tt
//
LOCUS       DAVBOD010000170          344 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 640-05
            SAMEA1012484-rid20186543.denovo.171, whole genome shotgun sequence.
ACCESSION   DAVBOD010000170 DAVBOD010000000
VERSION     DAVBOD010000170.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012484
            Sequence Read Archive: ERR059358
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 344)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 344)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979948.1
            Genome Coverage       :: 595x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:03:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,266
            CDSs (total)                      :: 2,219
            Genes (coding)                    :: 2,091
            CDSs (with protein)               :: 2,091
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 71 of 128
            Pseudo Genes (incomplete)         :: 50 of 128
            Pseudo Genes (internal stop)      :: 33 of 128
            Pseudo Genes (multiple problems)  :: 22 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..344
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012484-rid20186543.denovo.171"
                     /strain="NIG 640-05"
                     /db_xref="taxon:1313"
     gene            complement(<1..>344)
                     /locus_tag="VQ862_002244"
     CDS             complement(<1..>344)
                     /locus_tag="VQ862_002244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000212172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3116494.1"
                     /translation="LMAILEQATAKYGDTLSNSVNGRISLFKSLMKDAALNLGNSMLP
                     IINAIMPVLNSFAMVLKNVTAKLAEFIALMFNKKATVKDGVGGAVGDMGNAMKDAAGG
                     AGDLADAVDDAG"
BASE COUNT           92 a           92 c           67 g           93 t
ORIGIN      
        1 tctccagcgt cgtctactgc gtcagcaagg tctcctgctc cgcctgcagc gtctttcatg
       61 gcgttaccca tgtctccaac tgctccacca acaccatctt tcactgttgc tttcttgttg
      121 aacatcaaag cgataaactc agcgagttta gccgtcacgt tcttcaaaac catagcaaaa
      181 gagttcaaga caggcataat ggcattgata atcggtaaca tagagttacc aaggttcaat
      241 gctgcgtcct tcattagcga cttaaacagg ctgatacgac catttacaga attagacaag
      301 gtatctccat acttggctgt agcttgctcc aggatagcca taag
//
LOCUS       DAVBOD010000171          332 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 640-05
            SAMEA1012484-rid20186543.denovo.172, whole genome shotgun sequence.
ACCESSION   DAVBOD010000171 DAVBOD010000000
VERSION     DAVBOD010000171.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012484
            Sequence Read Archive: ERR059358
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 332)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 332)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979948.1
            Genome Coverage       :: 595x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:03:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,266
            CDSs (total)                      :: 2,219
            Genes (coding)                    :: 2,091
            CDSs (with protein)               :: 2,091
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 71 of 128
            Pseudo Genes (incomplete)         :: 50 of 128
            Pseudo Genes (internal stop)      :: 33 of 128
            Pseudo Genes (multiple problems)  :: 22 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..332
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012484-rid20186543.denovo.172"
                     /strain="NIG 640-05"
                     /db_xref="taxon:1313"
     gene            <1..>332
                     /locus_tag="VQ862_002245"
     CDS             <1..>332
                     /locus_tag="VQ862_002245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tail fiber domain-containing protein"
                     /protein_id="HET3116495.1"
                     /translation="KPKVSKGRLKSDWSPALEDTEGLITEAKATFERTAQGLRTDLSA
                     IQEYVNKDGQRQEALQRYTREESTRQATAVRELVNRDFVGKATYQEDVKGINQRIEAV
                     KTSANKDIA"
BASE COUNT          105 a           71 c           89 g           67 t
ORIGIN      
        1 aagcctaaag tctcgaaagg tcgcttaaaa agcgattgga gcccagctct ggaagacacc
       61 gaaggcctca tcactgaggc taaggcaacc tttgagcgga cagctcaggg cttgcgaacc
      121 gacttatcag ctattcagga atatgtaaat aaagacggtc agcgacagga agccctacag
      181 cgctatactc gtgaggagag cacgagacaa gcgacagcag tccgtgagct ggtcaatcgt
      241 gatttcgttg gtaaggctac ttatcaagaa gatgttaagg gtatcaatca gaggattgaa
      301 gctgttaaaa ctagtgcgaa taaagacatc gc
//
LOCUS       DAVBOD010000172          305 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 640-05
            SAMEA1012484-rid20186543.denovo.173, whole genome shotgun sequence.
ACCESSION   DAVBOD010000172 DAVBOD010000000
VERSION     DAVBOD010000172.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012484
            Sequence Read Archive: ERR059358
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 305)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 305)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979948.1
            Genome Coverage       :: 595x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:03:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,266
            CDSs (total)                      :: 2,219
            Genes (coding)                    :: 2,091
            CDSs (with protein)               :: 2,091
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 71 of 128
            Pseudo Genes (incomplete)         :: 50 of 128
            Pseudo Genes (internal stop)      :: 33 of 128
            Pseudo Genes (multiple problems)  :: 22 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..305
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012484-rid20186543.denovo.173"
                     /strain="NIG 640-05"
                     /db_xref="taxon:1313"
     gene            119..>305
                     /locus_tag="VQ862_002246"
     CDS             119..>305
                     /locus_tag="VQ862_002246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3116496.1"
                     /translation="MGRIYPETLIHLDISGYGNRVHSVHRFPGILLSVGESIQLKMLF
                     YKRLRNFTTDRFLTFRES"
BASE COUNT          100 a           49 c           64 g           92 t
ORIGIN      
        1 atattcagga agaagaaaaa aacaagaaac gccgtcgcca atattttctg cacgaccaat
       61 ttttgacgaa gttccaattg tagaagaagt taaggttgag ttcggagttg aagctagtat
      121 ggggcgcata tatccagaaa cgttaataca tttagatatt tctggatacg gaaatagagt
      181 gcattcagta catcgcttcc ccggtatttt actgagtgtt ggtgagtcaa tccaactaaa
      241 gatgcttttc tataaaagac ttagaaattt tactacagat cgtttcttga cgtttagaga
      301 atctg
//
LOCUS       DAVBOD010000173          304 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 640-05
            SAMEA1012484-rid20186543.denovo.174, whole genome shotgun sequence.
ACCESSION   DAVBOD010000173 DAVBOD010000000
VERSION     DAVBOD010000173.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012484
            Sequence Read Archive: ERR059358
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 304)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 304)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979948.1
            Genome Coverage       :: 595x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:03:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,266
            CDSs (total)                      :: 2,219
            Genes (coding)                    :: 2,091
            CDSs (with protein)               :: 2,091
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 71 of 128
            Pseudo Genes (incomplete)         :: 50 of 128
            Pseudo Genes (internal stop)      :: 33 of 128
            Pseudo Genes (multiple problems)  :: 22 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..304
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012484-rid20186543.denovo.174"
                     /strain="NIG 640-05"
                     /db_xref="taxon:1313"
     gene            <1..>304
                     /locus_tag="VQ862_002247"
     CDS             <1..>304
                     /locus_tag="VQ862_002247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002644521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3116497.1"
                     /translation="EIAKQAEALSRTKNELAGASTLLAQEAKRIELDSVARLEAFKSQ
                     TTSAQTALSGDLDVLKQTIANDIRPKQAQAEAEIAKQVEALSRTKNELAGVKSAQAT"
BASE COUNT           91 a           68 c           83 g           62 t
ORIGIN      
        1 ctgagattgc caagcaagct gaagcactta gccggactaa aaatgaactg gctggcgcaa
       61 gtaccctact tgcacaggaa gctaagcgga ttgagctgga ttctgttgct agacttgaag
      121 cgtttaagtc gcagactacg agcgctcaga cggctttgtc aggtgacttg gatgttctaa
      181 aacaaactat cgcaaacgat attcgaccga agcaagcaca ggctgaagct gagattgcca
      241 agcaagttga agcacttagc cggactaaga atgaactggc tggcgtgaag tcagcgcaag
      301 cgac
//
LOCUS       DAVBOD010000174          297 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 640-05
            SAMEA1012484-rid20186543.denovo.175, whole genome shotgun sequence.
ACCESSION   DAVBOD010000174 DAVBOD010000000
VERSION     DAVBOD010000174.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012484
            Sequence Read Archive: ERR059358
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 297)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 297)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979948.1
            Genome Coverage       :: 595x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:03:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,266
            CDSs (total)                      :: 2,219
            Genes (coding)                    :: 2,091
            CDSs (with protein)               :: 2,091
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 71 of 128
            Pseudo Genes (incomplete)         :: 50 of 128
            Pseudo Genes (internal stop)      :: 33 of 128
            Pseudo Genes (multiple problems)  :: 22 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..297
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012484-rid20186543.denovo.175"
                     /strain="NIG 640-05"
                     /db_xref="taxon:1313"
     gene            116..>297
                     /locus_tag="VQ862_002248"
     CDS             116..>297
                     /locus_tag="VQ862_002248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS1380 family transposase"
                     /protein_id="HET3116498.1"
                     /translation="MNSLPNHHFQNKSFYQLSFDGGHLTQYGGLIFFQELFSQLKLKE
                     RISKYLVTNDQRRYCR"
BASE COUNT           95 a           57 c           49 g           96 t
ORIGIN      
        1 cttagatcct ggatggtttc ttttttcacc caatgggtgt tttttactag acaaaaaaga
       61 gtttcccctt tatggtataa gtgtagaaaa aaacacaaaa agaaaggaaa ctcacatgaa
      121 cagtttacca aatcatcact tccaaaacaa gtctttttac caactatctt tcgatggagg
      181 tcatttaacc cagtatggtg gtcttatctt ttttcaggaa cttttttccc agttgaaact
      241 aaaagagcgg atttctaagt atttagtaac gaatgaccaa cgccgctact gtcgtta
//
LOCUS       DAVBOD010000175          288 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 640-05
            SAMEA1012484-rid20186543.denovo.176, whole genome shotgun sequence.
ACCESSION   DAVBOD010000175 DAVBOD010000000
VERSION     DAVBOD010000175.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012484
            Sequence Read Archive: ERR059358
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 288)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 288)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979948.1
            Genome Coverage       :: 595x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:03:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,266
            CDSs (total)                      :: 2,219
            Genes (coding)                    :: 2,091
            CDSs (with protein)               :: 2,091
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 71 of 128
            Pseudo Genes (incomplete)         :: 50 of 128
            Pseudo Genes (internal stop)      :: 33 of 128
            Pseudo Genes (multiple problems)  :: 22 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..288
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012484-rid20186543.denovo.176"
                     /strain="NIG 640-05"
                     /db_xref="taxon:1313"
     gene            complement(<1..285)
                     /locus_tag="VQ862_002249"
     CDS             complement(<1..285)
                     /locus_tag="VQ862_002249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004246694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3116499.1"
                     /translation="MPIEEAEKIAQSQVAWAILFILLFFIIIRYLIKTSDKREKKIMD
                     LHEQSKADSNRREERLMTHLEKTTTELTTITHTVGDIQKEMVRMNDRMEEI"
BASE COUNT           72 a           61 c           55 g          100 t
ORIGIN      
        1 gatttcttcc atgcggtcgt tcatgcgaac catttctttt tgaatgtctc cgaccgtgtg
       61 agtgattgtg gttaattctg tagtggtctt ttctaggtga gtcatcaaac gctcttctcg
      121 tctattagag tcggcctttg attgctcgtg caaatccata atcttcttct ctcgcttgtc
      181 cgaagtcttg ataagatatc gaatgataat aaaaaaaagc aagataaaca aaatcgccca
      241 agctacctga ctttgagcga ttttttcagc ttcttcaatt ggcataca
//
LOCUS       DAVBOD010000176          283 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 640-05
            SAMEA1012484-rid20186543.denovo.177, whole genome shotgun sequence.
ACCESSION   DAVBOD010000176 DAVBOD010000000
VERSION     DAVBOD010000176.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012484
            Sequence Read Archive: ERR059358
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 283)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 283)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979948.1
            Genome Coverage       :: 595x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:03:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,266
            CDSs (total)                      :: 2,219
            Genes (coding)                    :: 2,091
            CDSs (with protein)               :: 2,091
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 71 of 128
            Pseudo Genes (incomplete)         :: 50 of 128
            Pseudo Genes (internal stop)      :: 33 of 128
            Pseudo Genes (multiple problems)  :: 22 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..283
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012484-rid20186543.denovo.177"
                     /strain="NIG 640-05"
                     /db_xref="taxon:1313"
BASE COUNT           86 a           55 c           79 g           63 t
ORIGIN      
        1 ctgaggtgta agtcctcggt gggcacctgt taccggtgaa cccaatagcg attcccaagc
       61 ctgactatcg tgaggtagcg gattaaaacg gtctggggat agaccgtttt aaatctgacg
      121 ctggaaataa gaatcgtcag aggaagggat agcgaactcg tggctctacg aacaggaacg
      181 tgatagtaag gcgtatatag cggataaggg ggcctcaaac tctaaagttc aaaaaggtag
      241 tcgtaaccta tatgcgtaaa tcacgagagc aactgaattt gtc
//
LOCUS       DAVBOD010000177          269 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 640-05
            SAMEA1012484-rid20186543.denovo.178, whole genome shotgun sequence.
ACCESSION   DAVBOD010000177 DAVBOD010000000
VERSION     DAVBOD010000177.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012484
            Sequence Read Archive: ERR059358
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 269)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 269)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979948.1
            Genome Coverage       :: 595x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:03:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,266
            CDSs (total)                      :: 2,219
            Genes (coding)                    :: 2,091
            CDSs (with protein)               :: 2,091
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 71 of 128
            Pseudo Genes (incomplete)         :: 50 of 128
            Pseudo Genes (internal stop)      :: 33 of 128
            Pseudo Genes (multiple problems)  :: 22 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..269
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012484-rid20186543.denovo.178"
                     /strain="NIG 640-05"
                     /db_xref="taxon:1313"
     gene            <1..>269
                     /locus_tag="VQ862_002250"
     CDS             <1..>269
                     /locus_tag="VQ862_002250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001021764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1642 domain-containing protein"
                     /protein_id="HET3116500.1"
                     /translation="FVAEWIEEARKACKDVVELFEFDFTNDEVRKWFMQERPFDLVAR
                     AWLDGYEVEEEKRYLVTLKNRQPLVKSQSGSTLYFSQDITARNYKG"
BASE COUNT           90 a           31 c           71 g           77 t
ORIGIN      
        1 tttgtggctg aatggattga ggaagctaga aaagcttgta aagacgtggt agaattattc
       61 gaatttgatt tcacgaacga tgaagttaga aaatggttta tgcaagaaag accatttgat
      121 ttagtagcta gagcatggct tgatggctac gaggtcgagg aagagaagcg gtatttggtg
      181 actttaaaaa ataggcagcc tttggtcaaa tcgcaatcag ggagtactct ttattttagt
      241 caagatataa cagctaggaa ttataaagg
//
LOCUS       DAVBOD010000178          267 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 640-05
            SAMEA1012484-rid20186543.denovo.179, whole genome shotgun sequence.
ACCESSION   DAVBOD010000178 DAVBOD010000000
VERSION     DAVBOD010000178.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012484
            Sequence Read Archive: ERR059358
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 267)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 267)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979948.1
            Genome Coverage       :: 595x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:03:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,266
            CDSs (total)                      :: 2,219
            Genes (coding)                    :: 2,091
            CDSs (with protein)               :: 2,091
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 71 of 128
            Pseudo Genes (incomplete)         :: 50 of 128
            Pseudo Genes (internal stop)      :: 33 of 128
            Pseudo Genes (multiple problems)  :: 22 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..267
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012484-rid20186543.denovo.179"
                     /strain="NIG 640-05"
                     /db_xref="taxon:1313"
     gene            complement(<1..>267)
                     /locus_tag="VQ862_002251"
     CDS             complement(<1..>267)
                     /locus_tag="VQ862_002251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET3116501.1"
                     /translation="ELVEFFLQFHQLNQLIVDIDSTHFTTYGKQEGVAYNAHYRAHGY
                     HPLYAFEGKTGYCFNAQLRPGNRYCSEEADSFITPVLERFNQLL"
BASE COUNT           91 a           49 c           60 g           67 t
ORIGIN      
        1 aagagaagtt gattaaaccg ttctaaaaca ggtgtgataa agctgtctgc ctcttcagaa
       61 caataacgat taccaggacg aagctgggca ttgaaacaat aacctgtctt cccctcgaaa
      121 gcataaagag gatgatagcc atgagcacga tagtgggcgt tataagcaac accttcttgc
      181 ttgccataag ttgtgaaatg ggtagaatcg atatctacaa tgagttggtt tagctggtga
      241 aactgtaaaa agaattcgac caattca
//
LOCUS       DAVBOD010000179          254 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 640-05
            SAMEA1012484-rid20186543.denovo.180, whole genome shotgun sequence.
ACCESSION   DAVBOD010000179 DAVBOD010000000
VERSION     DAVBOD010000179.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012484
            Sequence Read Archive: ERR059358
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 254)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 254)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979948.1
            Genome Coverage       :: 595x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:03:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,266
            CDSs (total)                      :: 2,219
            Genes (coding)                    :: 2,091
            CDSs (with protein)               :: 2,091
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 71 of 128
            Pseudo Genes (incomplete)         :: 50 of 128
            Pseudo Genes (internal stop)      :: 33 of 128
            Pseudo Genes (multiple problems)  :: 22 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..254
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012484-rid20186543.denovo.180"
                     /strain="NIG 640-05"
                     /db_xref="taxon:1313"
     gene            <1..176
                     /locus_tag="VQ862_002252"
     CDS             <1..176
                     /locus_tag="VQ862_002252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000084419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="PBSX family phage terminase large subunit"
                     /protein_id="HET3116502.1"
                     /translation="KNIMDEFYSYCYQRDKEGNWLNKPEDKNNHLMDALRYSLQCIEG
                     GKATVRRRSDYGL"
BASE COUNT           87 a           43 c           60 g           64 t
ORIGIN      
        1 gtaaaaacat catggatgaa ttttatagtt actgctacca gcgagataaa gaaggcaact
       61 ggttgaataa accagaggat aaaaacaacc acttgatgga cgctttgcgt tacagccttc
      121 aatgtatcga aggtgggaaa gcaaccgtcc gcagacgttc tgattatggt ctatagagag
      181 gaaagacatg taccaatatt taacctatcc acgggatgga tatgatgagg gttctttgaa
      241 gaaagacctg attt
//
LOCUS       DAVBOD010000180          236 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 640-05
            SAMEA1012484-rid20186543.denovo.181, whole genome shotgun sequence.
ACCESSION   DAVBOD010000180 DAVBOD010000000
VERSION     DAVBOD010000180.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012484
            Sequence Read Archive: ERR059358
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 236)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 236)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979948.1
            Genome Coverage       :: 595x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:03:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,266
            CDSs (total)                      :: 2,219
            Genes (coding)                    :: 2,091
            CDSs (with protein)               :: 2,091
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 71 of 128
            Pseudo Genes (incomplete)         :: 50 of 128
            Pseudo Genes (internal stop)      :: 33 of 128
            Pseudo Genes (multiple problems)  :: 22 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..236
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012484-rid20186543.denovo.181"
                     /strain="NIG 640-05"
                     /db_xref="taxon:1313"
BASE COUNT           65 a           58 c           38 g           75 t
ORIGIN      
        1 ctatcatttc cctgatttca agcaccgtca aatcccaaaa atcaagaggc ttgcccccga
       61 tgtccaaaaa cataggataa agcctctcaa taatctgagt taccgttaag attacttgac
      121 tactgtcatt ttcttcttgg aagttttctt gtccttgctt cctcgtggag taaaacccga
      181 tacttcaaag agtggcatta aaacctctgt catgaatgtt gtttggtctc caccat
//
LOCUS       DAVBOD010000181          229 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 640-05
            SAMEA1012484-rid20186543.denovo.182, whole genome shotgun sequence.
ACCESSION   DAVBOD010000181 DAVBOD010000000
VERSION     DAVBOD010000181.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012484
            Sequence Read Archive: ERR059358
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 229)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 229)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979948.1
            Genome Coverage       :: 595x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:03:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,266
            CDSs (total)                      :: 2,219
            Genes (coding)                    :: 2,091
            CDSs (with protein)               :: 2,091
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 71 of 128
            Pseudo Genes (incomplete)         :: 50 of 128
            Pseudo Genes (internal stop)      :: 33 of 128
            Pseudo Genes (multiple problems)  :: 22 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..229
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012484-rid20186543.denovo.182"
                     /strain="NIG 640-05"
                     /db_xref="taxon:1313"
     gene            <1..>229
                     /locus_tag="VQ862_002253"
     CDS             <1..>229
                     /locus_tag="VQ862_002253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3116503.1"
                     /translation="GVISAGEYYFSADLYATDLGTHIKFGFYYHNSTGKLNFYAGRTK
                     IEVTEKGRWTRLGIDLKVNDDIDLTKKVQFY"
BASE COUNT           76 a           41 c           45 g           67 t
ORIGIN      
        1 tcggagtcat ctcagctgga gagtattact tttcagctga tttgtatgcg acagatttag
       61 gcactcatat caaatttgga ttttactatc acaactcgac tggcaaactc aatttttacg
      121 caggtcgaac aaaaattgaa gttactgaaa aaggccgttg gactaggcta ggaattgact
      181 taaaggtcaa tgatgacatt gacctgacaa aaaaagtcca attttacat
//
LOCUS       DAVBOD010000182          223 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 640-05
            SAMEA1012484-rid20186543.denovo.183, whole genome shotgun sequence.
ACCESSION   DAVBOD010000182 DAVBOD010000000
VERSION     DAVBOD010000182.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012484
            Sequence Read Archive: ERR059358
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 223)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 223)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979948.1
            Genome Coverage       :: 595x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:03:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,266
            CDSs (total)                      :: 2,219
            Genes (coding)                    :: 2,091
            CDSs (with protein)               :: 2,091
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 71 of 128
            Pseudo Genes (incomplete)         :: 50 of 128
            Pseudo Genes (internal stop)      :: 33 of 128
            Pseudo Genes (multiple problems)  :: 22 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..223
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012484-rid20186543.denovo.183"
                     /strain="NIG 640-05"
                     /db_xref="taxon:1313"
     gene            complement(<1..>223)
                     /locus_tag="VQ862_002254"
     CDS             complement(<1..>223)
                     /locus_tag="VQ862_002254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3116504.1"
                     /translation="LGRRAGESDGFTIVKKVVSSKKLSTSRCEDVSVTFNSGEMDNAY
                     IRFDNNGSSSGTADLYITEVDLYKGYKPRT"
BASE COUNT           62 a           49 c           36 g           76 t
ORIGIN      
        1 atgttctagg tttataacct ttgtacaagt caacttctgt aatatacaaa tcagctgttc
       61 ctgatgatga gccattgtta tcaaaacgaa tgtaagcatt atccatttct ccggaattaa
      121 aagttactga gacatcttcg catctagagg tagatagttt cttgctgcta acaactttct
      181 taacgattgt gaatccatcg ctctcgcctg ctcttcgtcc caa
//
LOCUS       DAVBOD010000183          217 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 640-05
            SAMEA1012484-rid20186543.denovo.184, whole genome shotgun sequence.
ACCESSION   DAVBOD010000183 DAVBOD010000000
VERSION     DAVBOD010000183.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012484
            Sequence Read Archive: ERR059358
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 217)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 217)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979948.1
            Genome Coverage       :: 595x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:03:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,266
            CDSs (total)                      :: 2,219
            Genes (coding)                    :: 2,091
            CDSs (with protein)               :: 2,091
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 71 of 128
            Pseudo Genes (incomplete)         :: 50 of 128
            Pseudo Genes (internal stop)      :: 33 of 128
            Pseudo Genes (multiple problems)  :: 22 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..217
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012484-rid20186543.denovo.184"
                     /strain="NIG 640-05"
                     /db_xref="taxon:1313"
BASE COUNT           68 a           47 c           24 g           78 t
ORIGIN      
        1 ggttcgtcta gttgtttgat tgtatctatg attctgtcta catcaataca attgataaat
       61 ctacttttac tttcttttaa aacgttacaa taatcaatca attcctgctt attcatctta
      121 gtttcctcca taaatcaaat aaactgcaat aactacctga gccatgcttg gcgaatagcc
      181 aatccaatca tcaaactcct tagattttgg caaccaa
//
LOCUS       DAVBOD010000184          216 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 640-05
            SAMEA1012484-rid20186543.denovo.185, whole genome shotgun sequence.
ACCESSION   DAVBOD010000184 DAVBOD010000000
VERSION     DAVBOD010000184.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012484
            Sequence Read Archive: ERR059358
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 216)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 216)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979948.1
            Genome Coverage       :: 595x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:03:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,266
            CDSs (total)                      :: 2,219
            Genes (coding)                    :: 2,091
            CDSs (with protein)               :: 2,091
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 71 of 128
            Pseudo Genes (incomplete)         :: 50 of 128
            Pseudo Genes (internal stop)      :: 33 of 128
            Pseudo Genes (multiple problems)  :: 22 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..216
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012484-rid20186543.denovo.185"
                     /strain="NIG 640-05"
                     /db_xref="taxon:1313"
     gene            complement(70..>216)
                     /locus_tag="VQ862_002255"
     CDS             complement(70..>216)
                     /locus_tag="VQ862_002255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000233204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3116505.1"
                     /translation="EIHLFVEFLKEQYGQGRPDYIEALNDLDGLVEVSYREAIERFLE
                     DEVR"
BASE COUNT           51 a           55 c           35 g           75 t
ORIGIN      
        1 ttcgaatact cgattatctt ctcttcgttt tgctcgatcg tgcgtttcag tccgtcaatc
       61 tcagcctgtt tatcgtactt catcttctaa aaatctttca atagcttctc tgtaggagac
      121 ttccaccaga ccgtctaagt cgttcagggc ttcaatatag tctggacgac cttgcccgta
      181 ctgctctttc aaaaattcaa caaagagatg aatttc
//
LOCUS       DAVBOD010000185         9424 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 640-05
            SAMEA1012484-rid20186543.guided.073, whole genome shotgun sequence.
ACCESSION   DAVBOD010000185 DAVBOD010000000
VERSION     DAVBOD010000185.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012484
            Sequence Read Archive: ERR059358
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9424)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9424)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979948.1
            Genome Coverage       :: 595x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:03:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,266
            CDSs (total)                      :: 2,219
            Genes (coding)                    :: 2,091
            CDSs (with protein)               :: 2,091
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 71 of 128
            Pseudo Genes (incomplete)         :: 50 of 128
            Pseudo Genes (internal stop)      :: 33 of 128
            Pseudo Genes (multiple problems)  :: 22 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9424
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012484-rid20186543.guided.073"
                     /strain="NIG 640-05"
                     /db_xref="taxon:1313"
     gene            30..1061
                     /locus_tag="VQ862_002256"
     CDS             30..1061
                     /locus_tag="VQ862_002256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HET3116506.1"
                     /translation="MTRAGITLIITTAFSISTMLYTLSAGYPFFLIAFLQIVTFAGIY
                     FKLGDLMSMFSLQSNDSQSVGSRVMRKPRMLMHAHMHRLQRKLGRSMTTLGAGSAIVT
                     GKKGQSGSGSSARTQADHSRPDGKEKSTLGKRIGQTIGTVADTKDRMVDTASGLKEQV
                     KDLPTNARYAVYQGKSKVKENVRDLTSSISQTKADRASGRKEQQEQRRKTIAKRRSEM
                     EQVKQKKQPASSVHERPTTRQEQYHDEQTSKQSNIQTSYKESQQAKQDRPAVKSDFSS
                     PKVERQGNTVQEKTVQKPATSTTTADRTSQRPITKERPSTVQRVPLQNTRSRPPIKTA
                     TIKKVGKKP"
     gene            1058..2059
                     /locus_tag="VQ862_002257"
     CDS             1058..2059
                     /locus_tag="VQ862_002257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018368130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysozyme/C40 family peptidase"
                     /protein_id="HET3116507.1"
                     /translation="MKLKTLVIGGSGLFLMVFSLLLFVAILFSDEQDSGISNIHYGGV
                     NVSAEVLAHKPMVEKYAKEYGVEEYVNILLAIIQVESGGTAEDVMQSSESLGLPPNSL
                     STEESIKQGVKYFSELLASSERLSVDLESVIQSYNYGGGFLGYVANRGNKYTFELAQS
                     FSKEYSGGEKVSYPNPIAIPINGGWRYNYGNMFYVQLVTQYLVTTEFDDDTVQAIMDE
                     ALKYEGWRYVYGGASPTTSFDCSGLTQWTYGKAGINLPRTAQQQYDVTQHIPLSEAQA
                     GDLVFFHSTYNAGSYITHVGIYLGNNRMFHAGDPIGYADLTSPYWQQHLVGAGRIKQ"
     gene            2056..2991
                     /locus_tag="VQ862_002258"
     CDS             2056..2991
                     /locus_tag="VQ862_002258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HET3116508.1"
                     /translation="MRKEDLMMKFRKNQNKEKQIPKEKKPRVYYKVNPHKKVVIALWV
                     LLGLSFSFAIFKHFTAIDTHTIHETTIIEKEYVDTHHVENFVENFAKVYYSWEQSDKS
                     IDNRMESLKGYLTDELQALNVDTVRKDIPVSSSVRGFQIWTVEPTGDNEFNVTYSVDQ
                     LITEGENTKTVHSAYIVSVYVDGSGNMVLVKNPTITNIPKKSSYKPKAIESEGTVDSI
                     TTNEINEFLTTFFKLYPTATASELSYYVNDGILKPIGKEYIFQELVNPIHNRKDNQVT
                     VSLTVEYIDQQTKATQVSQFDLVLEKNGSNWKIIE"
     gene            3236..3352
                     /locus_tag="VQ862_002259"
     CDS             3236..3352
                     /locus_tag="VQ862_002259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance determinant leader
                     peptide"
                     /protein_id="HET3116509.1"
                     /translation="MILKYPENICMLCMPMVMHKNPSDKSIYHWDFYALLGF"
     gene            3368..5287
                     /gene="tet(M)"
                     /locus_tag="VQ862_002260"
     CDS             3368..5287
                     /gene="tet(M)"
                     /locus_tag="VQ862_002260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011117014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance ribosomal protection
                     protein Tet(M)"
                     /protein_id="HET3116510.1"
                     /translation="MKIINIGVLAHVDAGKTTLTESLLYNSGAITELGSVDRGTTKTD
                     NTLLERQRGITIQTAITSFQWKNTKINIIDTPGHMDFLAEVYRSLSVLDGAILLISAK
                     DGVQAQTRILFHALRKIGIPTIFFINKIDQNGIDLSTVYQDIKEKLSAEIVIKQKVEL
                     HPNMRVMNFTESEQWDMVIEGNDYLLEKYTSGKLLEALELEQEESIRFHNCSLFPVYH
                     GSAKNNIGIDNLIEVITNKFYSSTHRGQSELCGKVFKIEYSEKRQRLAYIRLYSGVLH
                     LRDSVRISEKEKIKITEMYTSINGELCKIDKAYSGEIVILQNEFLKLNSVLGDTKLLP
                     QRERIENPLPLLQTTVEPSKPQQREMLLDALLEISDSDPLLRYYVDSATHEIILSFLG
                     KVQMEVTCALLQEKYHVEIEIKEPTVIYMERPLKKAEYTIHIEVPPNPFWASIGLSVA
                     PLPLGSGVQYESSVSLGYLNQSFQNAVMEGIRYGCEQGLYGWNVTDCKICFKYGLYYS
                     PVSTPADFRMLAPIVLEQVLKKAGTELLEPYLSFKIYAPQEYLSRAYNDAPKYCANIV
                     DTQLKNNEVILSGEIPARCIQEYRSDLTSFTNGRSVCLTELKGYHVTTGEPVCQPRRP
                     NSRIDKVRYMFNKIT"
     gene            5406..5573
                     /locus_tag="VQ862_002261"
     CDS             5406..5573
                     /locus_tag="VQ862_002261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine-rich KTR domain-containing protein"
                     /protein_id="HET3116511.1"
                     /translation="MCPVCGNKTRLKIREDTELKKFPLYCPKCRQENLIEIKQFKVTV
                     ITEPDAKTQSR"
     gene            complement(5633..5986)
                     /locus_tag="VQ862_002262"
     CDS             complement(5633..5986)
                     /locus_tag="VQ862_002262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HET3116512.1"
                     /translation="MRKKEDKYDFRAFGLAIKEARLKRSLTREQVGALIEIDPRYLTN
                     IENKGQHPSIQVLYDLVSLLHVSVDEFFLPANNLVKSTRRLQIEKYMDSFTDKELSLM
                     ESLASGINEARNIED"
     gene            6491..6913
                     /locus_tag="VQ862_002263"
     CDS             6491..6913
                     /locus_tag="VQ862_002263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006733729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HET3116513.1"
                     /translation="MKPSSFQTTIENQFDYICKRAMEDERKNYMLYLSRIAKREVSFS
                     DVGDYLVSQFATTDNYSTDFQIFTLNGLSVGVENDLLSEALRELPDKKREILLLFYFM
                     DMSDSEIADLLKLNRSTVYRHRTSGLALIKKFMEEFEE"
     gene            6910..7140
                     /locus_tag="VQ862_002264"
     CDS             6910..7140
                     /locus_tag="VQ862_002264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002411750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HET3116514.1"
                     /translation="MKTQYPMIPFPLIVKATDGDTEAINQILHHYRGYITKRSLRLMK
                     DEYGNQSMVVDEVLRGRMETRLITKILSFEIK"
     gene            7601..7804
                     /locus_tag="VQ862_002265"
     CDS             7601..7804
                     /locus_tag="VQ862_002265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006730246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excisionase"
                     /protein_id="HET3116515.1"
                     /translation="MKQTDIPIWERYTLTIEEASKYFRIGENKLRRLAEENKNANWLI
                     MNGNRIQIKRKQFEKIIDTLDAI"
     gene            7886..9103
                     /locus_tag="VQ862_002266"
     CDS             7886..9103
                     /locus_tag="VQ862_002266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020220015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HET3116516.1"
                     /translation="MSEKRRDNKGRILKTGESQRKDGRYLYKYIDSFGEPQFVYSWKL
                     VATDRVPAGKRDCISLREKIAELQKDIHDGIDVVGKKMTLCQLYAKQNAQRPKVRKNT
                     ETGRKYLMDILKKDKLGVRSIDSIKPSDAKEWAIRMSENGYAYQTINNYKRSLKASFY
                     IAIQDDCVRKNPFDFQLKAVLDDDTVPKTVLTEEQEEKLLAFAKADKTYSKNYDEILI
                     LLKTGLRISEFGGLTLPDLDFENRLVNIDHQLLRDTEIGYYIETPKTKSGERQVPMVE
                     EAYQAFKRVLANRKNDKRVEIDGYSDFLFLNRKNYPKVASDYNGMMKGLVKKYNKYNE
                     DKLPHITPHSLRHTFCTNYANAGMNPKALQYIMGHANIAMTLNYYAHATFDSAMAEMK
                     RLNKEKQQERLVA"
BASE COUNT         3211 a         1647 c         1902 g         2664 t
ORIGIN      
        1 gagccataac aaagctcttt aataccattt tgacacgagc tggaatcaca ttgattatta
       61 cgacagcatt tagtatttca accatgctct ataccttatc ggctggttat ccgttctttt
      121 tgattgcttt tctacagatt gtgacctttg caggaatcta cttcaagctg ggcgatttaa
      181 tgagtatgtt ttctctacag agtaacgatt ctcaaagtgt gggaagtcgt gtgatgagaa
      241 aacctcgtat gcttatgcac gctcacatgc accgtctaca gcggaaactt ggacgttcca
      301 tgactactct aggggctggg tctgccattg ttacaggtaa aaaaggacag tcgggttcgg
      361 ggagttctgc aaggacacaa gcagatcact cccgaccaga cggaaaggaa aaatcaacac
      421 ttggaaaacg tatcggtcaa accatcggta cagtagctga taccaaagac agaatggtag
      481 acactgctag tggtttgaaa gaacaggtta aagatttgcc gaccaatgca agatatgcag
      541 tatatcaagg aaaatccaaa gtaaaagaga atgtccgtga tttaaccagt agtatttctc
      601 aaaccaaagc ggacagagcc agtggacgca aggaacagca ggaacaaagg cgaaaaacca
      661 ttgcgaagcg tcgctctgaa atggaacagg tcaaacagaa aaaacagcct gcttcttctg
      721 ttcatgaaag accgactaca agacaagaac aatatcatga tgaacagacc tcaaaacagt
      781 ctaatattca gacttcatat aaggaatctc aacaagccaa acaagatcgt ccagcagtta
      841 agtccgattt ttcaagtcca aaagtggaac gccaaggcaa taccgttcaa gaaaaaaccg
      901 ttcaaaagcc agcaacttca accactacag cagatagaac ttcacaacgt ccaatcacaa
      961 aagaacgtcc gtctactgtt caaagagtac cactacaaaa tacaagaagt agaccaccaa
     1021 tcaaaaccgc caccattaag aaagtcggta agaaaccatg aagttgaaaa ctttagtgat
     1081 tggtggttct ggattattct tgatggtctt ctcactgctt ctgtttgttg ccattttatt
     1141 ttcagatgaa caggacagcg gaatttccaa tattcattat ggaggtgtga atgtttccgc
     1201 agaagtgctg gctcataagc ctatggtaga aaaatatgcc aaagaatatg gcgttgaaga
     1261 atatgtcaac atacttcttg cgattataca ggtggaatcg ggcggtactg cggaagatgt
     1321 tatgcagtcc tcggaatccc tcggtcttcc acctaattca ttgagtacag aagaatccat
     1381 taagcaaggt gtgaagtatt tcagtgaatt attagccagt agcgaaaggc tcagtgtaga
     1441 tttagaatcg gttatccagt cctacaatta tggtggtggt ttcttagggt atgtggctaa
     1501 tcgtggaaat aaatatacct ttgaactggc tcaaagtttc tcaaaagagt attcaggtgg
     1561 cgaaaaagtg tcttacccca atcccatagc catacctatc aatgggggct ggcgatacaa
     1621 ctatggcaat atgttttatg tgcaactggt aacgcagtat cttgtcacaa cagagtttga
     1681 tgatgatacg gtacaagcca tcatggacga agcactgaaa tatgagggct ggcgatacgt
     1741 ttacggtgga gcttccccga ctacttcttt tgattgtagc ggactgacac aatggacgta
     1801 tggaaaagct ggaattaact taccacgaac cgcacaacag caatatgatg tgacccagca
     1861 tatcccacta tcggaagcac aagctggcga tttggttttc tttcattcta cctataacgc
     1921 tggctcttat attactcatg ttgggatata ccttggcaat aaccgtatgt ttcatgcagg
     1981 cgacccaatc ggttatgccg acttaacaag cccctactgg caacagcatt tagtgggagc
     2041 aggacgaatc aaacaatgag aaaggaagat ttaatgatga aatttagaaa aaatcagaat
     2101 aaagaaaaac agataccaaa ggaaaagaaa cctcgtgtct actataaggt caatcctcat
     2161 aaaaaggttg tgattgcctt gtgggtactt ttagggctta gtttcagctt tgcgatattc
     2221 aagcacttta cagctataga tactcatact attcacgaaa caactatcat agaaaaggaa
     2281 tacgttgata ctcatcatgt agaaaatttt gtagagaact ttgcgaaagt ctactattca
     2341 tgggagcaat ccgataagtc cattgataat cgaatggaaa gtctaaaagg ctatctgaca
     2401 gatgaacttc aagctctcaa tgttgataca gtacgcaaag atattcctgt atcgtcttct
     2461 gtaagaggat ttcagatatg gacggtagag ccaactggcg acaatgagtt taatgtaacc
     2521 tacagtgtag accagctcat tacagaggga gaaaatacaa agaccgtcca ctctgcttat
     2581 atagtgagtg tctatgtaga tggttctgga aatatggtac tggttaagaa tccgaccatt
     2641 accaacatac ctaagaaatc aagttataaa ccaaaagcca ttgaaagtga ggggacggtt
     2701 gattccatta caaccaatga aatcaatgag tttttaacga cgttcttcaa gctctatcct
     2761 acagcgacag ccagtgaact ttcctactat gtgaatgacg ggatattaaa gccaatcgga
     2821 aaagagtaca tctttcaaga actggtaaat cctattcaca atcgtaagga taatcaagtc
     2881 acggtatcgc tgacagtgga gtatatcgac cagcagacca aagcaacgca ggtatctcaa
     2941 tttgatttgg tacttgaaaa gaacgggagt aattggaaga ttatagaata acaaatattg
     3001 gtacattatt acagctattt tgtaatcacg tactctcttt gataaaaaat tggagattcc
     3061 tttacaaata tgctcttatg tgctattatt taagtatcta tttaaaagga gttaataaat
     3121 atgcggcaag gtattcttaa ataaactgtc aatttgatag tggaaacaaa taattggatg
     3181 tcctttttta ggagggctta gttttttgta cccagtttaa gaataccttt atcatgtgat
     3241 tctaaagtat ccggagaata tctgtatgct ttgtatgcct atggttatgc ataaaaatcc
     3301 cagtgataag agtatttatc actgggattt ttatgccctt ttgggctttt gaatggagga
     3361 aaatcacatg aaaattatta atattggagt tttagctcat gttgatgcgg gaaaaactac
     3421 cttaacagaa agcttattat ataacagtgg agcgattaca gaattaggaa gcgtggacag
     3481 aggtacaacg aaaacggata atacgctttt agaacgtcag agaggaatta caattcagac
     3541 ggcgataacc tcttttcagt ggaaaaatac taagataaac atcatagaca cgccaggaca
     3601 tatggatttt ttagcagaag tatatcgttc attatcagta ttagatgggg caattctact
     3661 gatttctgca aaagatggcg tacaagcaca aactcgtata ttgtttcatg cacttaggaa
     3721 aataggtatt cccacaatct tttttatcaa taagattgac caaaatggaa ttgatttatc
     3781 aacggtttat caggatatta aagagaaact ttctgcggaa attgtaatca aacagaaggt
     3841 agaactgcat cctaatatgc gtgtaatgaa ctttaccgaa tctgaacaat gggatatggt
     3901 aatagaagga aatgattacc ttttggagaa atatacgtct gggaaattat tggaagcatt
     3961 agaactcgaa caagaggaaa gcataagatt tcataattgt tccctgttcc ctgtttatca
     4021 cggaagtgca aaaaacaata tagggattga taaccttata gaagtgatta cgaataaatt
     4081 ttattcatca acacatcgag gtcagtctga actttgcgga aaagttttca aaattgagta
     4141 ttcggaaaaa agacagcgtc ttgcatatat acgtctttat agtggcgtac tgcatttgcg
     4201 agattcggtt agaatatcgg aaaaggaaaa aataaaaatt acagaaatgt atacttcaat
     4261 aaatggtgaa ttatgtaaaa tcgataaggc ttattccggg gaaattgtta ttttgcagaa
     4321 tgagtttttg aagttaaata gtgttcttgg agatacaaag ctattgccac agagagagag
     4381 aattgaaaat cccctccctc tgctgcaaac gactgttgaa ccgagcaaac ctcaacaaag
     4441 ggaaatgtta cttgatgcac ttttagaaat ctccgacagt gacccgcttc tgcgatatta
     4501 tgtggattct gcgacacatg aaatcatact ttctttctta gggaaagtac aaatggaagt
     4561 gacttgtgct ctgctgcaag aaaagtatca tgtggagata gaaataaaag agcctacagt
     4621 catttatatg gaaagaccgt taaaaaaagc agagtatacc attcacatcg aagttccacc
     4681 gaatcctttc tgggcttcca ttggtctatc tgtagcaccg cttccattag ggagcggagt
     4741 acagtatgag agctcggttt ctcttggata cttaaatcaa tcgtttcaaa atgcagttat
     4801 ggaggggata cgctatggct gtgaacaagg attgtatggt tggaatgtga cggactgtaa
     4861 aatctgtttt aagtatggct tatactatag ccctgttagt accccagcag attttcggat
     4921 gcttgctcct attgtattgg aacaagtctt aaaaaaagct ggaacagaat tgttagagcc
     4981 atatcttagt tttaaaattt atgcgccaca ggaatatctt tcacgagcat acaacgatgc
     5041 tcctaaatat tgtgcgaaca tcgtagacac tcaattgaaa aataatgagg tcattcttag
     5101 tggagaaatc cctgctcggt gtattcaaga atatcgtagt gatttaactt cctttacaaa
     5161 tggacgtagt gtttgtttaa cagagttaaa agggtaccat gttactaccg gtgaacctgt
     5221 ttgccagccc cgtcgtccaa atagtcggat agataaagta cgatatatgt tcaataaaat
     5281 aacttagtgt attttatgtt gttatataaa tatggtttct tgttaaataa gatgaaatat
     5341 tttttaataa agatttgaat taaagtgtaa aggaggagat agttattata aactacaagt
     5401 ggatattgtg tcctgtatgt ggaaataaaa cacgattaaa gataagggaa gatactgaat
     5461 taaaaaaatt ccccctctat tgtccgaaat gcagacaaga aaatttaatt gaaataaagc
     5521 agttcaaagt aactgtgatt acagagccag acgcaaagac gcagagccga taaaatgaga
     5581 ttaatacaat ctcattttat cggctctttc cgttatgtat ggattctttt aattagtctt
     5641 cgatgtttct tgcttcgttg ataccgctgg ctaaagattc cattaaggat agttctttgt
     5701 ctgtaaagct atccatgtat ttctctatct gtaatcgtcg ggtgcttttt accaagttat
     5761 tagcaggtaa gaaaaattca tcaacggaaa catgaagtaa cgatacaagg tcataaagaa
     5821 cttgtatgct ggggtgttgc cctttatttt caatattagt taagtaccgt gggtcaattt
     5881 caatcaatgc tcccacttgt tcacgagtta aacttcgttt caatcgagct tctttaatgg
     5941 ctaaaccaaa ggctctaaaa tcatatttat cttctttttt acgcatagta gaccacctct
     6001 atacatttta ttgttcctac tgaattaaaa acaggtatag aaaaacgtgt tatatggttt
     6061 ataggtttat atttaataaa aagcactact aaacgccaat aaaaaaaacc gttatatggt
     6121 agtgctattt acgctgttaa aatattgtat attacttcca aatggcggtt tgttggaggt
     6181 caacgtcgcc atgaagtaca tcatatacaa taaatttcct tacattgggt tcttgtcaaa
     6241 aaaagtcgtc tatctgcaat agataagtac gtccaccaat gtggttttat aaatcatata
     6301 gatagaataa cagaagcatg taaacagaga aataaatctg tttatatgct tttttggcta
     6361 ttcagaactt ttttacaaag tttatttatc agtaatgcaa caaatccccc tttcacattg
     6421 ggactaagag tgaaaggaga taaacgagca aggctcactt cctttcctag acagaaaggg
     6481 ggtgagaaac atgaaaccat cttcttttca gaccacaata gaaaatcagt ttgactatat
     6541 ctgtaaacgt gctatggaag acgagcgaaa gaattatatg ctttatcttt caaggattgc
     6601 aaagcgtgag gtgtcctttt cggatgttgg cgattatctt gttagccagt ttgcgacaac
     6661 agataactat tcaactgact ttcagatttt tacactcaat gggttatcag taggcgttga
     6721 aaatgatttg ttgagtgaag cattacgtga gttgccagac aagaaacgtg aaattctact
     6781 gctgttttac tttatggaca tgagcgattc agaaattgca gacctgttga aattgaaccg
     6841 ttctactgtc tatcggcata gaaccagtgg actagcctta attaaaaagt ttatggagga
     6901 atttgaagaa tgaaaacaca atatcctatg attccctttc ctctcattgt aaaggcaaca
     6961 gatggcgata ccgaagcgat taaccagatt ctacatcatt acagagggta cataacgaag
     7021 cgttccctac gacttatgaa agatgaatat ggcaatcaaa gtatggtcgt tgatgaagtc
     7081 ttacgtggaa gaatggaaac cagactgatt acaaagattt tgtcatttga aattaagtaa
     7141 tatcctctct cctttcgtgg aagcgtgcta aaccattcca cgcttcccga acagggaggt
     7201 ttgttattcc accaaagcat attgagcttt caatgtgttt tgataggcta acgagccatt
     7261 gttctttgaa aactgaataa aagtaatcga atacgtttcg ataagaaaag agccaacgga
     7321 actaaccgcc atgacctatc ttataaagat agcgagcgat tcatgttagt gatccgagaa
     7381 gcaatcttta gcaggattgc ctgcaacgac attcttatcg tgataatgat actcccatac
     7441 agtcaatagt ccgagcgtga taaaaccgtc gcaggcaatg agtatggcta catgagaacc
     7501 atgcaggggt ggaactcccg tgagctttgc taaagctgtt cgattgctgg taaaacaact
     7561 tttatgaaat ccaaataagt gatttggaaa ggaggatttt atgaagcaga ctgacattcc
     7621 tatttgggaa cgttataccc taaccattga agaagcgtca aaatattttc gtattggcga
     7681 aaacaagcta cgacgcttgg cagaggaaaa taaaaatgca aattggctga ttatgaatgg
     7741 caatcgtatt cagattaaac gaaaacaatt tgaaaaaatt atagatacat tggacgcaat
     7801 ctagcgtcgc caaagggtct tgtatatgat aaaatagtat taagtcgtat caaggctctt
     7861 tccataaagg aaaggagcaa atgccatgtc agaaaaaaga cgtgacaata aaggtcgaat
     7921 cttaaagact ggagagagcc aacgaaaaga cggaagatac ttatacaaat atatagattc
     7981 atttggagaa ccgcaatttg tttactcgtg gaaacttgtg gctacagacc gagtaccagc
     8041 aggaaagcgt gattgtatct cacttagaga gaaaatcgca gagttacaga aagacattca
     8101 tgatggtatt gatgttgtag gaaagaaaat gacactctgc cagctttacg caaaacagaa
     8161 cgctcaaaga ccaaaggtta gaaaaaacac tgaaactgga cgcaaatatc ttatggatat
     8221 tttgaagaaa gacaagttag gtgtaagaag tattgacagt attaagccat cagacgctaa
     8281 agaatgggct attagaatga gtgaaaatgg ttatgcttat caaaccatca ataactacaa
     8341 acgttcttta aaggcttcat tctatattgc tatacaagat gattgtgttc ggaagaatcc
     8401 atttgacttt caactgaaag cagttcttga tgatgatact gtccctaaga ccgtactaac
     8461 agaagaacag gaagaaaaac tgttagcctt tgcaaaagct gataaaacct acagcaaaaa
     8521 ttatgatgaa attctgatac tcttaaaaac aggtcttcgt atttcagagt ttggtggttt
     8581 gacacttcca gatttagatt ttgagaatcg tcttgtcaat atagaccatc agctattgag
     8641 agatactgaa attgggtact acattgaaac accaaagacc aaaagtggcg aacgtcaagt
     8701 tcctatggtt gaagaagcct atcaagcatt taagcgagtg ttagcgaatc gaaagaatga
     8761 taagcgtgtt gagattgatg gatatagtga tttcctcttt cttaatagaa agaactatcc
     8821 aaaagtggca agtgattaca acggcatgat gaaaggtctt gttaagaaat acaataagta
     8881 taacgaggat aaattgccac acatcactcc acatagtttg cgacatacat tctgtaccaa
     8941 ctatgcaaat gcaggaatga atccaaaggc attacagtac attatgggac atgctaatat
     9001 agccatgacg ctgaactatt acgcacatgc aacattcgat tctgcaatgg cagaaatgaa
     9061 acgcttgaat aaagagaagc aacaggagcg tcttgttgct tagtagtaca aatgaattta
     9121 ctacttattt accacttctg acagctaaga catgaggaaa tatgcaaaga aacgtgaagt
     9181 atcttcctac agtaaaaata ctcgaaagca catagaataa ggctttacga gcatttaaga
     9241 aaatataaaa agataattag aaatttatac tttgttttta ttaaaaagca gcaaactata
     9301 aactagtagg ttccacacta aatgtagccc catactgccc cacaagtccg atttatagcg
     9361 taccatccct aaaaacattc ccaatgaaac atataaacac caagctagaa tggttcctgg
     9421 atga
//
